BLASTX 2.2.25 [Feb-01-2011]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= Ziziphus21_contig00044414
         (280 letters)

Database: ./nr 
           77,306,371 sequences; 28,104,191,420 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

ref|XP_007582823.1| putative gtp cyclohydrolase-2 protein [Neofu...   154   3e-35
gb|EKG20671.1| hypothetical protein MPH_02026 [Macrophomina phas...   150   5e-34
gb|KKY16062.1| putative gtp cyclohydrolase-2 [Diplodia seriata]       147   2e-33
gb|KNG45734.1| vacuolar protein sorting-associated protein 73 [S...   129   1e-27
ref|XP_014562315.1| hypothetical protein COCVIDRAFT_32754 [Bipol...   129   1e-27
ref|XP_007682336.1| hypothetical protein COCMIDRAFT_31581 [Bipol...   129   1e-27
ref|XP_007711008.1| hypothetical protein COCCADRAFT_35698 [Bipol...   129   1e-27
ref|XP_008027907.1| hypothetical protein SETTUDRAFT_132521 [Seto...   129   1e-27
ref|XP_014082921.1| hypothetical protein COCC4DRAFT_159242 [Bipo...   129   1e-27
gb|EMD90778.1| hypothetical protein COCHEDRAFT_1226156 [Bipolari...   129   1e-27
ref|XP_007705496.1| hypothetical protein COCSADRAFT_128912 [Bipo...   129   1e-27
ref|XP_003842033.1| similar to GTP cyclohydrolase II [Leptosphae...   129   1e-27
ref|XP_003298147.1| hypothetical protein PTT_08757 [Pyrenophora ...   127   4e-27
ref|XP_001940071.1| GTP cyclohydrolase-2 [Pyrenophora tritici-re...   127   4e-27
ref|XP_001806265.1| hypothetical protein SNOG_16138 [Parastagono...   125   1e-26
gb|KIW03595.1| GTP cyclohydrolase II [Verruconis gallopava]           123   5e-26
gb|KEQ59721.1| hypothetical protein M437DRAFT_56083 [Aureobasidi...   119   1e-24
ref|XP_013349350.1| hypothetical protein AUEXF2481DRAFT_162811 [...   118   2e-24
gb|KEQ87800.1| hypothetical protein M438DRAFT_266523 [Aureobasid...   118   2e-24
ref|XP_013427639.1| hypothetical protein M436DRAFT_63692 [Aureob...   118   2e-24

>ref|XP_007582823.1| putative gtp cyclohydrolase-2 protein [Neofusicoccum parvum UCRNP2]
           gi|485925028|gb|EOD49697.1| putative gtp
           cyclohydrolase-2 protein [Neofusicoccum parvum UCRNP2]
          Length = 382

 Score =  154 bits (388), Expect = 3e-35
 Identities = 80/93 (86%), Positives = 80/93 (86%)
 Frame = -2

Query: 279 ANLLLRHPADARSYGLATAMLVXXXXXXXXXXXXLTNNPDKVAAVEGPNREVVVTERVAM 100
           ANLLLRHPADARSYGLATAMLV            LTNNPDKVAAVEGPNREVVV ERVAM
Sbjct: 288 ANLLLRHPADARSYGLATAMLVDLGLGGDEGIRLLTNNPDKVAAVEGPNREVVVKERVAM 347

Query: 99  VPLAWKKGQKGSEEVEKYLSTKIEKFKHMLSPD 1
           VPLAWKKGQKGSEEVEKYLSTKIEKFKHMLSPD
Sbjct: 348 VPLAWKKGQKGSEEVEKYLSTKIEKFKHMLSPD 380


>gb|EKG20671.1| hypothetical protein MPH_02026 [Macrophomina phaseolina MS6]
          Length = 373

 Score =  150 bits (378), Expect = 5e-34
 Identities = 78/93 (83%), Positives = 79/93 (84%)
 Frame = -2

Query: 279 ANLLLRHPADARSYGLATAMLVXXXXXXXXXXXXLTNNPDKVAAVEGPNREVVVTERVAM 100
           ANLLLRHPADARSYGLATAMLV            LTNNPDKVAAVEGPNREVVV ERV M
Sbjct: 279 ANLLLRHPADARSYGLATAMLVDLGLGGHGGIRLLTNNPDKVAAVEGPNREVVVKERVPM 338

Query: 99  VPLAWKKGQKGSEEVEKYLSTKIEKFKHMLSPD 1
           VPLAWKKGQKGSEEVEKYLSTKIEKFKHMLSP+
Sbjct: 339 VPLAWKKGQKGSEEVEKYLSTKIEKFKHMLSPN 371


>gb|KKY16062.1| putative gtp cyclohydrolase-2 [Diplodia seriata]
          Length = 379

 Score =  147 bits (372), Expect = 2e-33
 Identities = 76/93 (81%), Positives = 79/93 (84%)
 Frame = -2

Query: 279 ANLLLRHPADARSYGLATAMLVXXXXXXXXXXXXLTNNPDKVAAVEGPNREVVVTERVAM 100
           ANLLLRHPADARSYGLATAMLV            LTNNPDKVAAVEGPNREVVV +RVAM
Sbjct: 285 ANLLLRHPADARSYGLATAMLVDLGLGGDAGIRLLTNNPDKVAAVEGPNREVVVKDRVAM 344

Query: 99  VPLAWKKGQKGSEEVEKYLSTKIEKFKHMLSPD 1
           VPLAWK+G KGS+EVEKYLSTKIEKFKHMLSPD
Sbjct: 345 VPLAWKQGTKGSDEVEKYLSTKIEKFKHMLSPD 377


>gb|KNG45734.1| vacuolar protein sorting-associated protein 73 [Stemphylium
            lycopersici]
          Length = 854

 Score =  129 bits (323), Expect = 1e-27
 Identities = 71/93 (76%), Positives = 74/93 (79%), Gaps = 3/93 (3%)
 Frame = -2

Query: 279  ANLLLRHPADARSYGLATAMLVXXXXXXXXXXXXLTNNPDKVAAVEGPNREVVVTERVAM 100
            AN++LRHPADARSYGLATAML+            LTNNPDKV AVEGPNREVVV ERVAM
Sbjct: 759  ANIMLRHPADARSYGLATAMLMDLGLDGDKGIRLLTNNPDKVQAVEGPNREVVVRERVAM 818

Query: 99   VPLAWKK-GQKG--SEEVEKYLSTKIEKFKHML 10
            VPLAWK  G KG  SEEVEKYLSTKIEKFKHML
Sbjct: 819  VPLAWKTGGMKGIKSEEVEKYLSTKIEKFKHML 851


>ref|XP_014562315.1| hypothetical protein COCVIDRAFT_32754 [Bipolaris victoriae FI3]
            gi|578495310|gb|EUN32692.1| hypothetical protein
            COCVIDRAFT_32754 [Bipolaris victoriae FI3]
          Length = 865

 Score =  129 bits (323), Expect = 1e-27
 Identities = 71/93 (76%), Positives = 74/93 (79%), Gaps = 3/93 (3%)
 Frame = -2

Query: 279  ANLLLRHPADARSYGLATAMLVXXXXXXXXXXXXLTNNPDKVAAVEGPNREVVVTERVAM 100
            AN++LRHPADARSYGLATAML+            LTNNPDKV AVEGPNREVVV ERVAM
Sbjct: 770  ANIMLRHPADARSYGLATAMLMDLGLDGDRGIRLLTNNPDKVRAVEGPNREVVVRERVAM 829

Query: 99   VPLAWKK-GQKG--SEEVEKYLSTKIEKFKHML 10
            VPLAWK  G KG  SEEVEKYLSTKIEKFKHML
Sbjct: 830  VPLAWKTGGMKGIKSEEVEKYLSTKIEKFKHML 862


>ref|XP_007682336.1| hypothetical protein COCMIDRAFT_31581 [Bipolaris oryzae ATCC 44560]
            gi|576937527|gb|EUC51014.1| hypothetical protein
            COCMIDRAFT_31581 [Bipolaris oryzae ATCC 44560]
          Length = 860

 Score =  129 bits (323), Expect = 1e-27
 Identities = 71/93 (76%), Positives = 74/93 (79%), Gaps = 3/93 (3%)
 Frame = -2

Query: 279  ANLLLRHPADARSYGLATAMLVXXXXXXXXXXXXLTNNPDKVAAVEGPNREVVVTERVAM 100
            AN++LRHPADARSYGLATAML+            LTNNPDKV AVEGPNREVVV ERVAM
Sbjct: 765  ANIMLRHPADARSYGLATAMLMDLGLDGDRGIRLLTNNPDKVRAVEGPNREVVVRERVAM 824

Query: 99   VPLAWKK-GQKG--SEEVEKYLSTKIEKFKHML 10
            VPLAWK  G KG  SEEVEKYLSTKIEKFKHML
Sbjct: 825  VPLAWKTGGMKGIKSEEVEKYLSTKIEKFKHML 857


>ref|XP_007711008.1| hypothetical protein COCCADRAFT_35698 [Bipolaris zeicola 26-R-13]
            gi|576920505|gb|EUC34660.1| hypothetical protein
            COCCADRAFT_35698 [Bipolaris zeicola 26-R-13]
          Length = 865

 Score =  129 bits (323), Expect = 1e-27
 Identities = 71/93 (76%), Positives = 74/93 (79%), Gaps = 3/93 (3%)
 Frame = -2

Query: 279  ANLLLRHPADARSYGLATAMLVXXXXXXXXXXXXLTNNPDKVAAVEGPNREVVVTERVAM 100
            AN++LRHPADARSYGLATAML+            LTNNPDKV AVEGPNREVVV ERVAM
Sbjct: 770  ANIMLRHPADARSYGLATAMLMDLGLDGDRGIRLLTNNPDKVRAVEGPNREVVVRERVAM 829

Query: 99   VPLAWKK-GQKG--SEEVEKYLSTKIEKFKHML 10
            VPLAWK  G KG  SEEVEKYLSTKIEKFKHML
Sbjct: 830  VPLAWKTGGMKGIKSEEVEKYLSTKIEKFKHML 862


>ref|XP_008027907.1| hypothetical protein SETTUDRAFT_132521 [Setosphaeria turcica Et28A]
            gi|482807549|gb|EOA84485.1| hypothetical protein
            SETTUDRAFT_132521 [Setosphaeria turcica Et28A]
          Length = 859

 Score =  129 bits (323), Expect = 1e-27
 Identities = 71/93 (76%), Positives = 74/93 (79%), Gaps = 3/93 (3%)
 Frame = -2

Query: 279  ANLLLRHPADARSYGLATAMLVXXXXXXXXXXXXLTNNPDKVAAVEGPNREVVVTERVAM 100
            AN++LRHPADARSYGLATAML+            LTNNPDKV AVEGPNREVVV ERVAM
Sbjct: 764  ANIMLRHPADARSYGLATAMLIDLGLDGDRGIRLLTNNPDKVRAVEGPNREVVVRERVAM 823

Query: 99   VPLAWKKGQ-KG--SEEVEKYLSTKIEKFKHML 10
            VPLAWK G  KG  SEEVEKYLSTKIEKFKHML
Sbjct: 824  VPLAWKTGGIKGIKSEEVEKYLSTKIEKFKHML 856


>ref|XP_014082921.1| hypothetical protein COCC4DRAFT_159242 [Bipolaris maydis ATCC 48331]
            gi|477591941|gb|ENI09012.1| hypothetical protein
            COCC4DRAFT_159242 [Bipolaris maydis ATCC 48331]
          Length = 865

 Score =  129 bits (323), Expect = 1e-27
 Identities = 71/93 (76%), Positives = 74/93 (79%), Gaps = 3/93 (3%)
 Frame = -2

Query: 279  ANLLLRHPADARSYGLATAMLVXXXXXXXXXXXXLTNNPDKVAAVEGPNREVVVTERVAM 100
            AN++LRHPADARSYGLATAML+            LTNNPDKV AVEGPNREVVV ERVAM
Sbjct: 770  ANIMLRHPADARSYGLATAMLMDLGLDGDRGIRLLTNNPDKVRAVEGPNREVVVRERVAM 829

Query: 99   VPLAWKK-GQKG--SEEVEKYLSTKIEKFKHML 10
            VPLAWK  G KG  SEEVEKYLSTKIEKFKHML
Sbjct: 830  VPLAWKTGGMKGIKSEEVEKYLSTKIEKFKHML 862


>gb|EMD90778.1| hypothetical protein COCHEDRAFT_1226156 [Bipolaris maydis C5]
          Length = 390

 Score =  129 bits (323), Expect = 1e-27
 Identities = 71/93 (76%), Positives = 74/93 (79%), Gaps = 3/93 (3%)
 Frame = -2

Query: 279 ANLLLRHPADARSYGLATAMLVXXXXXXXXXXXXLTNNPDKVAAVEGPNREVVVTERVAM 100
           AN++LRHPADARSYGLATAML+            LTNNPDKV AVEGPNREVVV ERVAM
Sbjct: 295 ANIMLRHPADARSYGLATAMLMDLGLDGDRGIRLLTNNPDKVRAVEGPNREVVVRERVAM 354

Query: 99  VPLAWKK-GQKG--SEEVEKYLSTKIEKFKHML 10
           VPLAWK  G KG  SEEVEKYLSTKIEKFKHML
Sbjct: 355 VPLAWKTGGMKGIKSEEVEKYLSTKIEKFKHML 387


>ref|XP_007705496.1| hypothetical protein COCSADRAFT_128912 [Bipolaris sorokiniana
           ND90Pr] gi|451845761|gb|EMD59073.1| hypothetical protein
           COCSADRAFT_128912 [Bipolaris sorokiniana ND90Pr]
          Length = 390

 Score =  129 bits (323), Expect = 1e-27
 Identities = 71/93 (76%), Positives = 74/93 (79%), Gaps = 3/93 (3%)
 Frame = -2

Query: 279 ANLLLRHPADARSYGLATAMLVXXXXXXXXXXXXLTNNPDKVAAVEGPNREVVVTERVAM 100
           AN++LRHPADARSYGLATAML+            LTNNPDKV AVEGPNREVVV ERVAM
Sbjct: 295 ANIMLRHPADARSYGLATAMLMDLGLDGDRGIRLLTNNPDKVRAVEGPNREVVVRERVAM 354

Query: 99  VPLAWKK-GQKG--SEEVEKYLSTKIEKFKHML 10
           VPLAWK  G KG  SEEVEKYLSTKIEKFKHML
Sbjct: 355 VPLAWKTGGMKGIKSEEVEKYLSTKIEKFKHML 387


>ref|XP_003842033.1| similar to GTP cyclohydrolase II [Leptosphaeria maculans JN3]
           gi|312218609|emb|CBX98554.1| similar to GTP
           cyclohydrolase II [Leptosphaeria maculans JN3]
          Length = 415

 Score =  129 bits (323), Expect = 1e-27
 Identities = 70/93 (75%), Positives = 75/93 (80%), Gaps = 3/93 (3%)
 Frame = -2

Query: 279 ANLLLRHPADARSYGLATAMLVXXXXXXXXXXXXLTNNPDKVAAVEGPNREVVVTERVAM 100
           AN+LLRHPADARSYGLATAML+            LTNNPDKV AVEGPNREVVV ERVAM
Sbjct: 320 ANILLRHPADARSYGLATAMLMDLGLDGDRGIRLLTNNPDKVHAVEGPNREVVVRERVAM 379

Query: 99  VPLAWKK-GQKG--SEEVEKYLSTKIEKFKHML 10
           +P+AWK  G+KG  SEEVEKYLSTKIEKFKHML
Sbjct: 380 IPIAWKTGGEKGIKSEEVEKYLSTKIEKFKHML 412


>ref|XP_003298147.1| hypothetical protein PTT_08757 [Pyrenophora teres f. teres 0-1]
            gi|311328831|gb|EFQ93755.1| hypothetical protein
            PTT_08757 [Pyrenophora teres f. teres 0-1]
          Length = 870

 Score =  127 bits (318), Expect = 4e-27
 Identities = 70/93 (75%), Positives = 74/93 (79%), Gaps = 3/93 (3%)
 Frame = -2

Query: 279  ANLLLRHPADARSYGLATAMLVXXXXXXXXXXXXLTNNPDKVAAVEGPNREVVVTERVAM 100
            AN++LRHPADARSYGLATAML+            LTNNPDKV AVEGPNREVVV ERVAM
Sbjct: 775  ANIMLRHPADARSYGLATAMLMDLGLDGDRGIRLLTNNPDKVHAVEGPNREVVVKERVAM 834

Query: 99   VPLAWKK-GQKG--SEEVEKYLSTKIEKFKHML 10
            VP+AWK  G KG  SEEVEKYLSTKIEKFKHML
Sbjct: 835  VPIAWKTGGLKGIKSEEVEKYLSTKIEKFKHML 867


>ref|XP_001940071.1| GTP cyclohydrolase-2 [Pyrenophora tritici-repentis Pt-1C-BFP]
           gi|187976164|gb|EDU42790.1| GTP cyclohydrolase-2
           [Pyrenophora tritici-repentis Pt-1C-BFP]
          Length = 390

 Score =  127 bits (318), Expect = 4e-27
 Identities = 70/93 (75%), Positives = 74/93 (79%), Gaps = 3/93 (3%)
 Frame = -2

Query: 279 ANLLLRHPADARSYGLATAMLVXXXXXXXXXXXXLTNNPDKVAAVEGPNREVVVTERVAM 100
           AN++LRHPADARSYGLATAML+            LTNNPDKV AVEGPNREVVV ERVAM
Sbjct: 295 ANIMLRHPADARSYGLATAMLMDLALDGDRGIRLLTNNPDKVHAVEGPNREVVVRERVAM 354

Query: 99  VPLAWKK-GQKG--SEEVEKYLSTKIEKFKHML 10
           VP+AWK  G KG  SEEVEKYLSTKIEKFKHML
Sbjct: 355 VPIAWKTGGLKGIKSEEVEKYLSTKIEKFKHML 387


>ref|XP_001806265.1| hypothetical protein SNOG_16138 [Parastagonospora nodorum SN15]
           gi|111055390|gb|EAT76510.1| hypothetical protein
           SNOG_16138 [Parastagonospora nodorum SN15]
          Length = 395

 Score =  125 bits (314), Expect = 1e-26
 Identities = 69/93 (74%), Positives = 74/93 (79%), Gaps = 3/93 (3%)
 Frame = -2

Query: 279 ANLLLRHPADARSYGLATAMLVXXXXXXXXXXXXLTNNPDKVAAVEGPNREVVVTERVAM 100
           AN+LLRHPADARSYGLATAML+            LTNNPDKV AVEGP REVVV ERVAM
Sbjct: 300 ANILLRHPADARSYGLATAMLMDLGLGGERGIRLLTNNPDKVHAVEGPGREVVVRERVAM 359

Query: 99  VPLAWKK-GQKG--SEEVEKYLSTKIEKFKHML 10
           VPLAWK  G++G  S+EVEKYLSTKIEKFKHML
Sbjct: 360 VPLAWKTGGERGIKSDEVEKYLSTKIEKFKHML 392


>gb|KIW03595.1| GTP cyclohydrolase II [Verruconis gallopava]
          Length = 360

 Score =  123 bits (309), Expect = 5e-26
 Identities = 69/93 (74%), Positives = 73/93 (78%), Gaps = 3/93 (3%)
 Frame = -2

Query: 279 ANLLLRHPADARSYGLATAMLVXXXXXXXXXXXXLTNNPDKVAAVEGPNREVVVTERVAM 100
           ANLLLRHPADARSYGLATAMLV             TNNPDKV AVEGPNRE+ V ERVAM
Sbjct: 270 ANLLLRHPADARSYGLATAMLVDLGLKDVRLL---TNNPDKVRAVEGPNREIRVRERVAM 326

Query: 99  VPLAWKK-GQKG--SEEVEKYLSTKIEKFKHML 10
           +PLAW+  GQKG  SEEVEKYLSTKIEKFKHM+
Sbjct: 327 IPLAWQTGGQKGIKSEEVEKYLSTKIEKFKHMI 359


>gb|KEQ59721.1| hypothetical protein M437DRAFT_56083 [Aureobasidium melanogenum CBS
           110374]
          Length = 407

 Score =  119 bits (297), Expect = 1e-24
 Identities = 63/95 (66%), Positives = 69/95 (72%), Gaps = 3/95 (3%)
 Frame = -2

Query: 279 ANLLLRHPADARSYGLATAMLVXXXXXXXXXXXXLTNNPDKVAAVEGPNREVVVTERVAM 100
           ANLLLRHPADARSYGLATAML+            LTNNP+KV AVEGP REVVV ERV M
Sbjct: 312 ANLLLRHPADARSYGLATAMLMDLGLGGERGIRLLTNNPEKVRAVEGPGREVVVKERVPM 371

Query: 99  VPLAWKKGQK---GSEEVEKYLSTKIEKFKHMLSP 4
           +PLAW+ G K      E+EKY+ TKIEKFKHM SP
Sbjct: 372 IPLAWQSGGKEGVQGPELEKYIGTKIEKFKHMFSP 406


>ref|XP_013349350.1| hypothetical protein AUEXF2481DRAFT_162811 [Aureobasidium
           subglaciale EXF-2481] gi|662543552|gb|KER00850.1|
           hypothetical protein AUEXF2481DRAFT_162811
           [Aureobasidium subglaciale EXF-2481]
          Length = 400

 Score =  118 bits (296), Expect = 2e-24
 Identities = 62/95 (65%), Positives = 69/95 (72%), Gaps = 3/95 (3%)
 Frame = -2

Query: 279 ANLLLRHPADARSYGLATAMLVXXXXXXXXXXXXLTNNPDKVAAVEGPNREVVVTERVAM 100
           ANLLLRHPADARSYGLATAML+            LTNNP+KV AVEGPN+EVVV +RV M
Sbjct: 305 ANLLLRHPADARSYGLATAMLMDLGLGGDRGIRLLTNNPEKVRAVEGPNKEVVVKQRVPM 364

Query: 99  VPLAWKKGQK---GSEEVEKYLSTKIEKFKHMLSP 4
           +PLAW  G K      E+EKY+ TKIEKFKHM SP
Sbjct: 365 IPLAWSSGGKEGVQGPELEKYIGTKIEKFKHMFSP 399


>gb|KEQ87800.1| hypothetical protein M438DRAFT_266523 [Aureobasidium pullulans
           EXF-150]
          Length = 399

 Score =  118 bits (296), Expect = 2e-24
 Identities = 63/95 (66%), Positives = 68/95 (71%), Gaps = 3/95 (3%)
 Frame = -2

Query: 279 ANLLLRHPADARSYGLATAMLVXXXXXXXXXXXXLTNNPDKVAAVEGPNREVVVTERVAM 100
           ANLLLRHPADARSYGLATAML+            LTNNP+KV AVEGP REVVV ERV M
Sbjct: 304 ANLLLRHPADARSYGLATAMLMDLGLGGDRGIRLLTNNPEKVRAVEGPGREVVVKERVPM 363

Query: 99  VPLAWKKGQK---GSEEVEKYLSTKIEKFKHMLSP 4
           +PLAW  G K      E+EKY+ TKIEKFKHM SP
Sbjct: 364 IPLAWSSGGKEGVQGPELEKYIGTKIEKFKHMFSP 398


>ref|XP_013427639.1| hypothetical protein M436DRAFT_63692 [Aureobasidium namibiae CBS
           147.97] gi|662515821|gb|KEQ73386.1| hypothetical protein
           M436DRAFT_63692 [Aureobasidium namibiae CBS 147.97]
          Length = 403

 Score =  118 bits (296), Expect = 2e-24
 Identities = 63/95 (66%), Positives = 68/95 (71%), Gaps = 3/95 (3%)
 Frame = -2

Query: 279 ANLLLRHPADARSYGLATAMLVXXXXXXXXXXXXLTNNPDKVAAVEGPNREVVVTERVAM 100
           ANLLLRHPADARSYGLATAML+            LTNNP+KV AVEGP REVVV ERV M
Sbjct: 308 ANLLLRHPADARSYGLATAMLMDLGLGGDRGIRLLTNNPEKVRAVEGPGREVVVKERVPM 367

Query: 99  VPLAWKKGQK---GSEEVEKYLSTKIEKFKHMLSP 4
           +PLAW  G K      E+EKY+ TKIEKFKHM SP
Sbjct: 368 IPLAWSSGGKEGVQGPELEKYIGTKIEKFKHMFSP 402