BLASTX 2.2.25 [Feb-01-2011]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= Ziziphus21_contig00041021
         (1319 letters)

Database: ./nr 
           77,306,371 sequences; 28,104,191,420 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

ref|XP_014289471.1| PREDICTED: cathepsin B-like [Halyomorpha halys]   230   2e-57
ref|XP_014289457.1| PREDICTED: cathepsin B-like [Halyomorpha halys]   230   2e-57
ref|XP_002404474.1| cathepsin B endopeptidase, putative [Ixodes ...   225   8e-56
gb|ABU62925.1| cathepsin B [Fasciola hepatica]                        224   1e-55
gb|AAO73004.1| cathepsin B [Fasciola gigantica]                       224   2e-55
dbj|BAN21462.1| cathepsin B, partial [Riptortus pedestris]            222   5e-55
gb|ACG50796.1| cathepsin B1 [Trichobilharzia szidati]                 221   1e-54
gb|ACO14731.1| Cathepsin B precursor [Caligus clemensi]               219   3e-54
dbj|BAN20372.1| cathepsin B [Riptortus pedestris]                     219   4e-54
ref|XP_010993449.1| PREDICTED: cathepsin B [Camelus dromedarius]      219   5e-54
gb|AAO73003.1| cathepsin B [Fasciola gigantica]                       219   5e-54
ref|XP_010971493.1| PREDICTED: LOW QUALITY PROTEIN: cathepsin B ...   218   9e-54
gb|AAV65883.1| cathepsin B1 isotype 3 precursor [Trichobilharzia...   218   9e-54
gb|AAV65881.1| cathepsin B1 isotype 1 precursor [Trichobilharzia...   218   9e-54
gb|AID66461.1| cathepsin B [Micropterus salmoides]                    218   1e-53
ref|XP_006203342.1| PREDICTED: cathepsin B [Vicugna pacos]            218   1e-53
gb|ABO26563.1| cathepsin B-like cysteine protease form 1 [Ixodes...   218   1e-53
gb|KHJ99394.1| papain family cysteine protease [Oesophagostomum ...   217   2e-53
ref|XP_013297560.1| papain family cysteine protease [Necator ame...   217   2e-53
ref|XP_002635884.1| Hypothetical protein CBG01104 [Caenorhabditi...   217   2e-53

>ref|XP_014289471.1| PREDICTED: cathepsin B-like [Halyomorpha halys]
          Length = 334

 Score =  230 bits (587), Expect = 2e-57
 Identities = 119/262 (45%), Positives = 157/262 (59%), Gaps = 7/262 (2%)
 Frame = -3

Query: 900 TALPRSYDVRQRFSNSSSVSHIRDQSFCGSCWAVSAASVLSDRLYIHSKGRYNFELSSRY 721
           +++P S+D R  +S  +S+ HIRDQ  CGSCWAV+AA   +DRL I S   +   L+S  
Sbjct: 78  SSIPDSFDARDNWSQCASIRHIRDQGTCGSCWAVAAAGAFTDRLCIASNASFTLPLASEE 137

Query: 720 ILSXXXXXXXXXXGYLD-SVWDFLEREGTVTGGEFQTDEGCQPYPLHPCGW------PRK 562
           +L+          G    S WD+    G VTGG++Q++EGCQPY +  C        P  
Sbjct: 138 LLACCEECGDGCNGGDPYSAWDYFAENGLVTGGDYQSNEGCQPYEIQACEHHTTGKLPSC 197

Query: 561 LACPWYLTPKCLKTKCDNEWYKTPTELHMYKVRESYYVGDFFGLFNEYYIRDEIFRNGPV 382
            + P   TPKC + KC N  Y TP +   +KV+ +Y VGD     +   I+ EI  +GPV
Sbjct: 198 DSLPMSDTPKCQR-KCTNAAYTTPFKSDHHKVKRAYNVGD-----SVKEIQKEIMTHGPV 251

Query: 381 QAGFYVYADFLAYKSGIYYHKKRSKLLGGHAVKIIGWGEEKGVKYWIIANSWGEEWGENG 202
           +A F VYADFL YKSG+Y H    + L GHAVKIIGWG E G  YW+IAN W E WG+ G
Sbjct: 252 EAAFTVYADFLTYKSGVYQHVT-GEALAGHAVKIIGWGVENGTPYWLIANQWNESWGDKG 310

Query: 201 TFRMIRGKDNCGIEDEVYAGIP 136
            F+ +RGKD+CG+E E+ AGIP
Sbjct: 311 LFKFLRGKDHCGMESEIVAGIP 332


>ref|XP_014289457.1| PREDICTED: cathepsin B-like [Halyomorpha halys]
          Length = 333

 Score =  230 bits (587), Expect = 2e-57
 Identities = 119/264 (45%), Positives = 157/264 (59%), Gaps = 7/264 (2%)
 Frame = -3

Query: 900 TALPRSYDVRQRFSNSSSVSHIRDQSFCGSCWAVSAASVLSDRLYIHSKGRYNFELSSRY 721
           +++P S+D R+ +    S+ HIRDQ  CGSCWAV+AA   +DR+ I + G +   LSS  
Sbjct: 78  SSIPDSFDARENWPQCDSIRHIRDQGTCGSCWAVAAAGAFTDRVCIATNGTFTKPLSSEE 137

Query: 720 ILSXXXXXXXXXXG-YLDSVWDFLEREGTVTGGEFQTDEGCQPYPLHPCGW------PRK 562
           +L+          G Y  S W F    G VTGG++Q++EGCQPY +  C        P  
Sbjct: 138 LLACCSECGNGCNGGYPFSAWKFFAYNGLVTGGDYQSNEGCQPYEIQACEHHTTGKLPSC 197

Query: 561 LACPWYLTPKCLKTKCDNEWYKTPTELHMYKVRESYYVGDFFGLFNEYYIRDEIFRNGPV 382
            + P   TPKC + KC N  Y TP     +K+++ Y +           I+ EI  +GPV
Sbjct: 198 DSLPMSKTPKCQR-KCTNAAYSTPFSSDHHKIKQVYTIDGV------KEIQKEIMAHGPV 250

Query: 381 QAGFYVYADFLAYKSGIYYHKKRSKLLGGHAVKIIGWGEEKGVKYWIIANSWGEEWGENG 202
           +AG+ VYADF  YKSG+Y+H    K LGGHAVKIIGWG E G  YW+IAN W E WG+ G
Sbjct: 251 EAGYTVYADFPTYKSGVYHHVT-GKALGGHAVKIIGWGVEDGTPYWLIANQWNESWGDKG 309

Query: 201 TFRMIRGKDNCGIEDEVYAGIPAL 130
            F++IRGKD+CGIE E+ AGIP L
Sbjct: 310 LFKIIRGKDHCGIESEIVAGIPKL 333


>ref|XP_002404474.1| cathepsin B endopeptidase, putative [Ixodes scapularis]
           gi|215491571|gb|EEC01212.1| cathepsin B endopeptidase,
           putative [Ixodes scapularis]
          Length = 337

 Score =  225 bits (573), Expect = 8e-56
 Identities = 114/258 (44%), Positives = 163/258 (63%), Gaps = 5/258 (1%)
 Frame = -3

Query: 894 LPRSYDVRQRFSNSSSVSHIRDQSFCGSCWAVSAASVLSDRLYIHSKGRYNFELSSRYIL 715
           LP S+D R+++S+ +S+  IRDQS CGSCWA  AA  +SDR+ IHSKG+   ++S+  +L
Sbjct: 85  LPESFDAREKWSHCASIHLIRDQSTCGSCWAFGAAEAMSDRVCIHSKGKIQVDISAEDLL 144

Query: 714 SXXXXXXXXXXG-YLDSVWDFLEREGTVTGGEFQTDEGCQPYPLHPCGWPRKLACP---- 550
                      G Y  + W++ +  G VTGG + T +GC+PY L PC    K + P    
Sbjct: 145 DCCDSCGAGCNGGYPAAAWEYWKESGLVTGGLYGTSDGCKPYSLAPCEHHTKGSLPNCTG 204

Query: 549 WYLTPKCLKTKCDNEWYKTPTELHMYKVRESYYVGDFFGLFNEYYIRDEIFRNGPVQAGF 370
              TPKC+   C  + Y    +   +  R+ Y +       +E  I+ EIF+NGPV+A F
Sbjct: 205 TVPTPKCVHL-C-RKGYGKDYQDDKHFGRKVYSISS-----DEKQIQTEIFKNGPVEADF 257

Query: 369 YVYADFLAYKSGIYYHKKRSKLLGGHAVKIIGWGEEKGVKYWIIANSWGEEWGENGTFRM 190
            VYADFL+YKSG+Y H+    +LGGHA++I+GWG E G  YW++ANSW E+WG++G F++
Sbjct: 258 TVYADFLSYKSGVYQHQS-GDVLGGHAIRILGWGTENGTPYWLVANSWNEDWGDHGYFKI 316

Query: 189 IRGKDNCGIEDEVYAGIP 136
           +RGKD CGIED++ AGIP
Sbjct: 317 LRGKDECGIEDDINAGIP 334


>gb|ABU62925.1| cathepsin B [Fasciola hepatica]
          Length = 337

 Score =  224 bits (571), Expect = 1e-55
 Identities = 125/260 (48%), Positives = 156/260 (60%), Gaps = 7/260 (2%)
 Frame = -3

Query: 894 LPRSYDVRQRFSNSSSVSHIRDQSFCGSCWAVSAASVLSDRLYIHSKGRYNFELSSRYIL 715
           LP S+D RQ+++N  S+S IRDQS C SCWAVS+AS ++DR+ IHS G+    LS+  I+
Sbjct: 86  LPESFDARQKWANCPSISEIRDQSSCSSCWAVSSASAITDRICIHSNGQKKPRLSAIDIV 145

Query: 714 SXXXXXXXXXXGYLDSV-WDFLEREGTVTGGEFQTDEGCQPYPLHPCGW----PRKLACP 550
           S          G + ++ WD+  REG VTGG  +   GC PYP   C      P    CP
Sbjct: 146 SCCAYCGYGCNGGIPAMSWDYWTREGVVTGGTLENPTGCLPYPFPKCSHGVVTPGLPPCP 205

Query: 549 W--YLTPKCLKTKCDNEWYKTPTELHMYKVRESYYVGDFFGLFNEYYIRDEIFRNGPVQA 376
              Y TPKC K KC   + KT  E    K + SY VG       E  I  EI +NGPV  
Sbjct: 206 RDIYPTPKCEK-KCHAGYNKT-YEQDKVKGKSSYNVGG-----QETDIMMEIMKNGPVDG 258

Query: 375 GFYVYADFLAYKSGIYYHKKRSKLLGGHAVKIIGWGEEKGVKYWIIANSWGEEWGENGTF 196
            FY++ DFL YKSGIY H    +L+GGHA+++IGWG E GVKYW+IANSW E WGE G F
Sbjct: 259 IFYMFEDFLVYKSGIY-HYTTGRLVGGHAIRVIGWGVENGVKYWLIANSWNEGWGEKGYF 317

Query: 195 RMIRGKDNCGIEDEVYAGIP 136
           RM RG + CGIE  + AG+P
Sbjct: 318 RMRRGNNECGIEARINAGLP 337


>gb|AAO73004.1| cathepsin B [Fasciola gigantica]
          Length = 337

 Score =  224 bits (570), Expect = 2e-55
 Identities = 124/260 (47%), Positives = 156/260 (60%), Gaps = 7/260 (2%)
 Frame = -3

Query: 894 LPRSYDVRQRFSNSSSVSHIRDQSFCGSCWAVSAASVLSDRLYIHSKGRYNFELSSRYIL 715
           LP S+D RQ+++N  S+S IRDQS C SCWAVS+AS ++DR+ IHS G+    LS+  I+
Sbjct: 86  LPESFDARQKWANCPSISEIRDQSSCSSCWAVSSASAITDRICIHSNGQKKPRLSAIDIV 145

Query: 714 SXXXXXXXXXXGYLDSV-WDFLEREGTVTGGEFQTDEGCQPYPLHPCGW----PRKLACP 550
           S          G + ++ WD+  REG VTGG  +   GC PYP   C      P    CP
Sbjct: 146 SCCAYCGYGCNGGIPAMSWDYWTREGVVTGGTLENPTGCLPYPFPKCSHGVVTPGLPPCP 205

Query: 549 W--YLTPKCLKTKCDNEWYKTPTELHMYKVRESYYVGDFFGLFNEYYIRDEIFRNGPVQA 376
              Y TPKC K KC   + KT  E    K + SY VG+      E     EI +NGPV  
Sbjct: 206 RDIYPTPKCEK-KCHAGYNKT-YEQDKVKGKSSYNVGE-----QETDFMMEIMKNGPVDG 258

Query: 375 GFYVYADFLAYKSGIYYHKKRSKLLGGHAVKIIGWGEEKGVKYWIIANSWGEEWGENGTF 196
            FY++ DFL YKSGIY H    +L+GGHA+++IGWG E GVKYW+IANSW E WGE G F
Sbjct: 259 IFYMFEDFLVYKSGIY-HYTTGRLVGGHAIRVIGWGVENGVKYWLIANSWNEGWGEKGYF 317

Query: 195 RMIRGKDNCGIEDEVYAGIP 136
           RM RG + CGIE  + AG+P
Sbjct: 318 RMRRGNNECGIEARINAGLP 337


>dbj|BAN21462.1| cathepsin B, partial [Riptortus pedestris]
          Length = 332

 Score =  222 bits (566), Expect = 5e-55
 Identities = 134/354 (37%), Positives = 186/354 (52%), Gaps = 8/354 (2%)
 Frame = -3

Query: 1173 FIAIVFLISSVLANHHKKFEHEKINLREIAAEVNSDPRSLWKADAYGFDEVPVNEIXXXX 994
            F  ++F++++ +  H  K   E  NL +I   VNS   + WKA     ++V ++ I    
Sbjct: 3    FNFLIFILATSV--HGAKIHFE--NLNDIIDHVNS-LETTWKAGNNFENDVTLSSIKKLL 57

Query: 993  XXXXXXXGQSTSNKYSKSKFGAQNRPKLGV-GTALPRSYDVRQRFSNSSSVSHIRDQSFC 817
                            KS F    R    +  T +P  +D R+ + +  ++ H+RDQ  C
Sbjct: 58   GL-------------KKSDFQLPVRELHDIPDTDIPEEFDARKNWPDCPTIGHVRDQGNC 104

Query: 816  GSCWAVSAASVLSDRLYIHSKGRYNFELSSRYILSXXXXXXXXXXG-YLDSVWDFLEREG 640
            GSCWAV+AA   SDRL I S G +   LS   +LS          G Y D  WDF  R G
Sbjct: 105  GSCWAVAAAGAFSDRLCIASNGNFTLPLSDEELLSCCRRCGHGCNGGYDDEAWDFFARNG 164

Query: 639  TVTGGEFQTDEGCQPYPLHPCGWPRK------LACPWYLTPKCLKTKCDNEWYKTPTELH 478
             VTGG++Q++ GCQPY +  C    K         P   TPKC K +C N  Y  P    
Sbjct: 165  IVTGGDYQSNVGCQPYEVQACEHRTKGPLPPCSTLPDAQTPKC-KKECTNPSYNNPFNQD 223

Query: 477  MYKVRESYYVGDFFGLFNEYYIRDEIFRNGPVQAGFYVYADFLAYKSGIYYHKKRSKLLG 298
             +KV+ +Y +       N   I+ EI  +GPV+AGF VY+DF  YKSG+Y++   S+L G
Sbjct: 224  HHKVKSAYSLTRG----NVREIQKEIMAHGPVEAGFTVYSDFPTYKSGVYHYVGGSEL-G 278

Query: 297  GHAVKIIGWGEEKGVKYWIIANSWGEEWGENGTFRMIRGKDNCGIEDEVYAGIP 136
            GHAV+IIGWG + G  YW++ NSW   WG+NG F++ RG D CGIE E+ AG+P
Sbjct: 279  GHAVRIIGWGTDNGTPYWLVVNSWNTHWGDNGLFKIRRGIDECGIESEISAGVP 332


>gb|ACG50796.1| cathepsin B1 [Trichobilharzia szidati]
          Length = 342

 Score =  221 bits (562), Expect = 1e-54
 Identities = 123/263 (46%), Positives = 158/263 (60%), Gaps = 6/263 (2%)
 Frame = -3

Query: 906 VGTALPRSYDVRQRFSNSSSVSHIRDQSFCGSCWAVSAASVLSDRLYIHSKGRYNFELSS 727
           V   +P S+D R+++    S+S+IRDQS CG CWA +A   +SDR+ I SKG+ + ELS+
Sbjct: 86  VSLEIPSSFDSRKKWRQCKSISNIRDQSRCGPCWAFAAVEAMSDRICIQSKGKKSVELSA 145

Query: 726 RYILSXXXXXXXXXXG-YLDSVWDFLEREGTVTGGEFQTDEGCQPYPLHPCGWPRKLACP 550
             +LS          G +  + WD+   EG VTG   +   GCQPYP   C    K   P
Sbjct: 146 VDLLSCCTECGLGCQGGFPGAAWDYWVEEGIVTGSSKENHTGCQPYPFPKCEHHTKGKYP 205

Query: 549 W-----YLTPKCLKTKCDNEWYKTPTELHMYKVRESYYVGDFFGLFNEYYIRDEIFRNGP 385
                 Y TPKC + KC  + YKTP +   Y  + SY V     L  E  I+ EI  +GP
Sbjct: 206 ACGEKIYKTPKC-QQKCQ-KGYKTPYKKDKYYGKLSYNV-----LSKEDAIKKEIMMHGP 258

Query: 384 VQAGFYVYADFLAYKSGIYYHKKRSKLLGGHAVKIIGWGEEKGVKYWIIANSWGEEWGEN 205
           V+A F VY+DFL YKSGIY H K + ++GGHAV+IIGWG EK   YW+IANSW E+WGE 
Sbjct: 259 VEAAFTVYSDFLNYKSGIYKHMKGT-VIGGHAVRIIGWGVEKKTPYWLIANSWNEDWGEK 317

Query: 204 GTFRMIRGKDNCGIEDEVYAGIP 136
           G FR++RGKD CGIE  V AG+P
Sbjct: 318 GYFRILRGKDVCGIESAVTAGLP 340


>gb|ACO14731.1| Cathepsin B precursor [Caligus clemensi]
          Length = 331

 Score =  219 bits (559), Expect = 3e-54
 Identities = 121/290 (41%), Positives = 167/290 (57%), Gaps = 14/290 (4%)
 Frame = -3

Query: 963 TSNKYSKSKFGAQNR---------PKLGVGTALPRSYDVRQRFSNSSSVSHIRDQSFCGS 811
           TS+ Y +S  G             P L    ++P ++D R+ + N  S+  IRDQ  CGS
Sbjct: 50  TSSNYIRSLMGVLPNHRDYLPPPLPNLLGTESIPDTFDAREHWPNCPSIRLIRDQGSCGS 109

Query: 810 CWAVSAASVLSDRLYIHSKGRYNFELSSRYILSXXXXXXXXXXG-YLDSVWDFLEREGTV 634
           CWA  AA  +SDR+ IH+    N  +S+  +LS          G +  + W F E +G V
Sbjct: 110 CWAFGAAEAMSDRVCIHT--HKNVNISAENLLSCCYTCGFGCNGGFPGAAWRFWENKGLV 167

Query: 633 TGGEFQTDEGCQPYPLHPC----GWPRKLACPWYLTPKCLKTKCDNEWYKTPTELHMYKV 466
           +GG + + +GCQPY + PC       RK       TPKC KT CDN+ Y    E  +   
Sbjct: 168 SGGLYGSHKGCQPYLIEPCEHHVNGTRKPCAEGGRTPKCHKT-CDNKNYPISYEKDLSFG 226

Query: 465 RESYYVGDFFGLFNEYYIRDEIFRNGPVQAGFYVYADFLAYKSGIYYHKKRSKLLGGHAV 286
           R SY +       +   I+ +I  NGPV+A F VY+DF++YKSG+Y H K S LLGGHA+
Sbjct: 227 RSSYSIRS-----DPKQIQMDIMTNGPVEAAFSVYSDFMSYKSGVYRHVKGS-LLGGHAI 280

Query: 285 KIIGWGEEKGVKYWIIANSWGEEWGENGTFRMIRGKDNCGIEDEVYAGIP 136
           +I+GWG EKG  YW++ANSW  +WG+NGTF+++RG D+CGIED V AG+P
Sbjct: 281 RILGWGMEKGTPYWLVANSWNTDWGDNGTFKILRGSDHCGIEDSVVAGLP 330


>dbj|BAN20372.1| cathepsin B [Riptortus pedestris]
          Length = 332

 Score =  219 bits (558), Expect = 4e-54
 Identities = 124/331 (37%), Positives = 179/331 (54%), Gaps = 6/331 (1%)
 Frame = -3

Query: 1110 EKINLREIAAEVNSDPRSLWKADAYGFDEVPVNEIXXXXXXXXXXXGQSTSNKYSKSKFG 931
            E +N  +IA  VNS   + WKAD      +PV+ I             +T  +  +S+F 
Sbjct: 20   ESVNFEDIAERVNS-LNTTWKADPNFPSNLPVSSIQWLFGAKES---DATLPELDESEFD 75

Query: 930  AQNRPKLGVGTALPRSYDVRQRFSNSSSVSHIRDQSFCGSCWAVSAASVLSDRLYIHSKG 751
              +         +P  +D R+++    ++S I +QS CGSCWAV+AAS  SDRL I SKG
Sbjct: 76   TND--------VIPEEFDARKKWPECPTISDIPNQSKCGSCWAVAAASAFSDRLCIASKG 127

Query: 750  RYNFELSSRYILSXXXXXXXXXXG-YLDSVWDFLEREGTVTGGEFQTDEGCQPYPLHPCG 574
            ++   LS+  +LS          G +    W++ +  G VTGG + +  GCQPYP   CG
Sbjct: 128  KFKSALSANELLSCCTDCGYGCDGGFPVEAWEYFKEVGIVTGGGYNSSIGCQPYPFPRCG 187

Query: 573  -----WPRKLACPWYLTPKCLKTKCDNEWYKTPTELHMYKVRESYYVGDFFGLFNEYYIR 409
                  P     P Y TP+C + KC N  Y    +   +K++++Y       L N   I+
Sbjct: 188  SSSDPLPPCSTLPDYKTPEC-QEKCTNPEYSAEYKQDHHKIKKTY------SLRNIELIQ 240

Query: 408  DEIFRNGPVQAGFYVYADFLAYKSGIYYHKKRSKLLGGHAVKIIGWGEEKGVKYWIIANS 229
             +I +NGPV+A F  Y DF+ YKSG+Y+H   +K+  GHAV+IIGWG + G  YW++ANS
Sbjct: 241  RDIMKNGPVEASFTAYQDFMTYKSGVYHHTV-TKVAAGHAVRIIGWGTDNGTPYWLVANS 299

Query: 228  WGEEWGENGTFRMIRGKDNCGIEDEVYAGIP 136
            W + WGE G FR++RG +  GIE  + AGIP
Sbjct: 300  WDKYWGEEGLFRILRGSNESGIEGSIVAGIP 330


>ref|XP_010993449.1| PREDICTED: cathepsin B [Camelus dromedarius]
          Length = 335

 Score =  219 bits (557), Expect = 5e-54
 Identities = 110/268 (41%), Positives = 159/268 (59%), Gaps = 6/268 (2%)
 Frame = -3

Query: 921 RPKLGVGTALPRSYDVRQRFSNSSSVSHIRDQSFCGSCWAVSAASVLSDRLYIHSKGRYN 742
           R  L    ALP+S+D R+++ N  ++  IRDQ  CGSCWA  A   +SDR+ IHS GR N
Sbjct: 71  RVALAGNMALPKSFDAREQWPNCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHSNGRVN 130

Query: 741 FELSSRYILSXXXXXXXXXXG--YLDSVWDFLEREGTVTGGEFQTDEGCQPYPLHPC--- 577
            E+S+  +L+             +    W+F  ++G V+GG + +  GC+PY + PC   
Sbjct: 131 VEVSAEDMLTCCGLECGEGCNGGFPSGAWNFWTKQGLVSGGLYDSHVGCRPYSIPPCEHH 190

Query: 576 -GWPRKLACPWYLTPKCLKTKCDNEWYKTPTELHMYKVRESYYVGDFFGLFNEYYIRDEI 400
               R        TPKC K  C+  +  TP+    YK  + +    +    N+  I  EI
Sbjct: 191 VNGSRPPCTGEGATPKCRKN-CEPGY--TPS----YKDDKHFGCSSYSVPSNQEEIMAEI 243

Query: 399 FRNGPVQAGFYVYADFLAYKSGIYYHKKRSKLLGGHAVKIIGWGEEKGVKYWIIANSWGE 220
           ++NGPV+  F VY+DFL YKSG+Y H K  +++GGHA++I+GWGEE G  YW++ NSW  
Sbjct: 244 YKNGPVEGAFSVYSDFLLYKSGVYQHVK-GEMMGGHAIRILGWGEENGTPYWLVGNSWNT 302

Query: 219 EWGENGTFRMIRGKDNCGIEDEVYAGIP 136
           +WG+NG F+++RG+D+CGIE EV AGIP
Sbjct: 303 DWGDNGFFKILRGQDHCGIESEVVAGIP 330


>gb|AAO73003.1| cathepsin B [Fasciola gigantica]
          Length = 339

 Score =  219 bits (557), Expect = 5e-54
 Identities = 120/262 (45%), Positives = 157/262 (59%), Gaps = 7/262 (2%)
 Frame = -3

Query: 894 LPRSYDVRQRFSNSSSVSHIRDQSFCGSCWAVSAASVLSDRLYIHSKGRYNFELSSRYIL 715
           LP S+D R ++    ++S IRDQ+ CGSCWA +AAS +SDR+ IHS G+    L++   L
Sbjct: 86  LPESFDARSQWPQCWTISEIRDQASCGSCWATAAASAMSDRVCIHSNGQMRPRLAAADPL 145

Query: 714 SXXXXXXXXXXG-YLDSVWDFLEREGTVTGGEFQTDEGCQPYPLHPC---GWPRKLA-CP 550
           S          G Y    WD+  REG VTGG ++   GCQP+    C   G  RK + CP
Sbjct: 146 SCCTYCGQGCRGGYPPKAWDYWMREGIVTGGTWENRTGCQPWMFTKCDHVGDSRKYSRCP 205

Query: 549 WYL--TPKCLKTKCDNEWYKTPTELHMYKVRESYYVGDFFGLFNEYYIRDEIFRNGPVQA 376
            Y   TP C +  C   + KT  +   Y    SY VG+     +E YI  EI +NGPV+ 
Sbjct: 206 HYTYPTPPCARA-CQTGYNKTYEQDKFYG-NSSYNVGE-----HESYIMQEIMKNGPVEV 258

Query: 375 GFYVYADFLAYKSGIYYHKKRSKLLGGHAVKIIGWGEEKGVKYWIIANSWGEEWGENGTF 196
            F ++ DF  Y+SGIY+H    K +G HAV++IGWG E GV YW++ANSW EEWGENG F
Sbjct: 259 TFAIFQDFGVYRSGIYHHVA-GKFIGRHAVRMIGWGVENGVNYWLMANSWNEEWGENGYF 317

Query: 195 RMIRGKDNCGIEDEVYAGIPAL 130
           RM+RG++ CGIE EV AG+P L
Sbjct: 318 RMVRGRNECGIESEVVAGMPRL 339


>ref|XP_010971493.1| PREDICTED: LOW QUALITY PROTEIN: cathepsin B [Camelus bactrianus]
          Length = 335

 Score =  218 bits (555), Expect = 9e-54
 Identities = 110/268 (41%), Positives = 158/268 (58%), Gaps = 6/268 (2%)
 Frame = -3

Query: 921 RPKLGVGTALPRSYDVRQRFSNSSSVSHIRDQSFCGSCWAVSAASVLSDRLYIHSKGRYN 742
           R  L    ALP+S+D R+++ N  ++  IRDQ  CGSCWA  A   +SDR+ IHS GR N
Sbjct: 71  RVALAGNMALPKSFDAREQWPNCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHSNGRVN 130

Query: 741 FELSSRYILSXXXXXXXXXXG--YLDSVWDFLEREGTVTGGEFQTDEGCQPYPLHPC--- 577
            E+S+  +L+             +    W+F  ++G V+GG + +  GC+PY + PC   
Sbjct: 131 VEVSAEDMLTCCGLECGEGCNGGFPSGAWNFWTKQGLVSGGLYDSHVGCRPYSIPPCEHH 190

Query: 576 -GWPRKLACPWYLTPKCLKTKCDNEWYKTPTELHMYKVRESYYVGDFFGLFNEYYIRDEI 400
               R        TPKC K   + E   TP+    YK  + +    +    N+  I  EI
Sbjct: 191 VNGSRPPCTGEGATPKCRK---NXEPGYTPS----YKDDKHFGCSSYSVPSNQEEIMAEI 243

Query: 399 FRNGPVQAGFYVYADFLAYKSGIYYHKKRSKLLGGHAVKIIGWGEEKGVKYWIIANSWGE 220
           ++NGPV+  F VY+DFL YKSG+Y H K  +++GGHA++I+GWGEE G  YW++ NSW  
Sbjct: 244 YKNGPVEGAFSVYSDFLLYKSGVYQHVK-GEMMGGHAIRILGWGEENGTPYWLVGNSWNT 302

Query: 219 EWGENGTFRMIRGKDNCGIEDEVYAGIP 136
           +WG+NG F+++RG+D+CGIE EV AGIP
Sbjct: 303 DWGDNGFFKILRGQDHCGIESEVVAGIP 330


>gb|AAV65883.1| cathepsin B1 isotype 3 precursor [Trichobilharzia regenti]
          Length = 342

 Score =  218 bits (555), Expect = 9e-54
 Identities = 121/263 (46%), Positives = 159/263 (60%), Gaps = 6/263 (2%)
 Frame = -3

Query: 906 VGTALPRSYDVRQRFSNSSSVSHIRDQSFCGSCWAVSAASVLSDRLYIHSKGRYNFELSS 727
           V   +P S+D R+++    S+S+IRDQS CGSCWA +A   +SDR+ I SKG+ + ELS+
Sbjct: 86  VSLEIPSSFDSRKKWHQCKSISNIRDQSRCGSCWAFTAVEAMSDRICIESKGKKSVELSA 145

Query: 726 RYILSXXXXXXXXXXG-YLDSVWDFLEREGTVTGGEFQTDEGCQPYPLHPC-----GWPR 565
             +LS          G +  + WD+   +G VTG   +   GCQPYP   C     G   
Sbjct: 146 VDLLSCCTECGLGCQGGFPGAAWDYWVEDGIVTGSSKENHTGCQPYPFPKCEHHTTGKYP 205

Query: 564 KLACPWYLTPKCLKTKCDNEWYKTPTELHMYKVRESYYVGDFFGLFNEYYIRDEIFRNGP 385
           +     Y TPKC + KC  + YKTP +   Y  R SY V     L NE  I+ EI  +GP
Sbjct: 206 ECGEKIYKTPKCHQ-KCQ-KGYKTPYKKDKYYGRMSYNV-----LNNENAIKKEIMMHGP 258

Query: 384 VQAGFYVYADFLAYKSGIYYHKKRSKLLGGHAVKIIGWGEEKGVKYWIIANSWGEEWGEN 205
           V+A F V++DFL YKSGIY +   +++ GGHAV+IIGWG EK   YW+IANSW E+WGE 
Sbjct: 259 VEAAFTVHSDFLNYKSGIYKYMTGAEI-GGHAVRIIGWGVEKKTPYWLIANSWNEDWGEK 317

Query: 204 GTFRMIRGKDNCGIEDEVYAGIP 136
           G FR++RGKD CGIE EV  G+P
Sbjct: 318 GYFRILRGKDECGIESEVTGGLP 340


>gb|AAV65881.1| cathepsin B1 isotype 1 precursor [Trichobilharzia regenti]
          Length = 342

 Score =  218 bits (555), Expect = 9e-54
 Identities = 121/263 (46%), Positives = 159/263 (60%), Gaps = 6/263 (2%)
 Frame = -3

Query: 906 VGTALPRSYDVRQRFSNSSSVSHIRDQSFCGSCWAVSAASVLSDRLYIHSKGRYNFELSS 727
           V   +P S+D R+++    S+S+IRDQS CGSCWA +A   +SDR+ I SKG+ + ELS+
Sbjct: 86  VSLEIPSSFDSRKKWHQCKSISNIRDQSRCGSCWAFAAVEAMSDRICIESKGKKSVELSA 145

Query: 726 RYILSXXXXXXXXXXG-YLDSVWDFLEREGTVTGGEFQTDEGCQPYPLHPC-----GWPR 565
             +LS          G +  + WD+   +G VTG   +   GCQPYP   C     G   
Sbjct: 146 VDLLSCCTECGLGCQGGFPGAAWDYWVEDGIVTGSSKENHTGCQPYPFPKCEHHTTGKYP 205

Query: 564 KLACPWYLTPKCLKTKCDNEWYKTPTELHMYKVRESYYVGDFFGLFNEYYIRDEIFRNGP 385
           +     Y TPKC + KC  + YKTP +   Y  R SY V     L NE  I+ EI  +GP
Sbjct: 206 ECGEKIYKTPKCHQ-KCQ-KGYKTPYKKDKYYGRMSYNV-----LNNENAIKKEIMMHGP 258

Query: 384 VQAGFYVYADFLAYKSGIYYHKKRSKLLGGHAVKIIGWGEEKGVKYWIIANSWGEEWGEN 205
           V+A F V++DFL YKSGIY +   +++ GGHAV+IIGWG EK   YW+IANSW E+WGE 
Sbjct: 259 VEAAFTVHSDFLNYKSGIYKYMTGAEI-GGHAVRIIGWGVEKKTPYWLIANSWNEDWGEK 317

Query: 204 GTFRMIRGKDNCGIEDEVYAGIP 136
           G FR++RGKD CGIE EV  G+P
Sbjct: 318 GYFRILRGKDECGIESEVTGGLP 340


>gb|AID66461.1| cathepsin B [Micropterus salmoides]
          Length = 330

 Score =  218 bits (554), Expect = 1e-53
 Identities = 112/259 (43%), Positives = 157/259 (60%), Gaps = 6/259 (2%)
 Frame = -3

Query: 894 LPRSYDVRQRFSNSSSVSHIRDQSFCGSCWAVSAASVLSDRLYIHSKGRYNFELSSRYIL 715
           LP+ +D R+ + N  ++  IRDQ  CGSCWA  AA  +SDR+ IHS  + + E+SS  +L
Sbjct: 79  LPKQFDAREHWPNCPTLKEIRDQGSCGSCWAFGAAEAISDRVCIHSNAKVSVEISSEDLL 138

Query: 714 SXXXXXXXXXXG-YLDSVWDFLEREGTVTGGEFQTDEGCQPYPLHPCGWPRKLACPWYL- 541
           +          G Y  + WDF  +EG V+GG F +  GC+PY + PC      + P    
Sbjct: 139 TCCESCGFGCNGGYPSAAWDFWTKEGLVSGGLFDSHVGCRPYTIPPCEHHVNGSRPSCTG 198

Query: 540 ----TPKCLKTKCDNEWYKTPTELHMYKVRESYYVGDFFGLFNEYYIRDEIFRNGPVQAG 373
               TP+C+  +C+  +  TP+    YK  + +    +  L NE  I+ EI++NGPV+  
Sbjct: 199 EGGDTPQCIN-ECEAGY--TPS----YKQDKHFGKTSYSVLSNEQEIQSEIYKNGPVEGA 251

Query: 372 FYVYADFLAYKSGIYYHKKRSKLLGGHAVKIIGWGEEKGVKYWIIANSWGEEWGENGTFR 193
           F VY DFL YK+G+Y H   S + GGHA+KI+GWGEE GV YW+ ANSW  +WG+NG F+
Sbjct: 252 FSVYEDFLMYKTGVYQHVSGSAV-GGHAIKILGWGEENGVPYWLCANSWNTDWGDNGFFK 310

Query: 192 MIRGKDNCGIEDEVYAGIP 136
           ++RG D+CGIE EV AGIP
Sbjct: 311 ILRGSDHCGIESEVVAGIP 329


>ref|XP_006203342.1| PREDICTED: cathepsin B [Vicugna pacos]
          Length = 334

 Score =  218 bits (554), Expect = 1e-53
 Identities = 107/260 (41%), Positives = 157/260 (60%), Gaps = 6/260 (2%)
 Frame = -3

Query: 897 ALPRSYDVRQRFSNSSSVSHIRDQSFCGSCWAVSAASVLSDRLYIHSKGRYNFELSSRYI 718
           ALP+S+D R+++ N  ++  IRDQ  CGSCWA  A   +SDR+ IHS GR N E+S+  +
Sbjct: 78  ALPKSFDAREQWPNCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHSNGRVNVEVSAEDM 137

Query: 717 LSXXXXXXXXXXG--YLDSVWDFLEREGTVTGGEFQTDEGCQPYPLHPC----GWPRKLA 556
           L+             +    W+F  ++G V+GG + +  GC+PY + PC       R   
Sbjct: 138 LTCCGLECGEGCNGGFPSGAWNFWTKQGLVSGGLYDSHVGCRPYSIPPCEHHVNGSRPPC 197

Query: 555 CPWYLTPKCLKTKCDNEWYKTPTELHMYKVRESYYVGDFFGLFNEYYIRDEIFRNGPVQA 376
                TPKC K  C+  +  TP+    YK  + +    +    N+  I  EI++NGPV+ 
Sbjct: 198 TGEGATPKCRKN-CEPGY--TPS----YKDDKHFGCSSYSVPSNQEEIMAEIYKNGPVEG 250

Query: 375 GFYVYADFLAYKSGIYYHKKRSKLLGGHAVKIIGWGEEKGVKYWIIANSWGEEWGENGTF 196
            F VY+DFL YKSG+Y H K  +++GGHA++I+GWGEE G  YW++ NSW  +WG+NG F
Sbjct: 251 AFSVYSDFLLYKSGVYQHVK-GEMMGGHAIRILGWGEENGTPYWLVGNSWNTDWGDNGFF 309

Query: 195 RMIRGKDNCGIEDEVYAGIP 136
           +++RG+D+CGIE EV AG+P
Sbjct: 310 KILRGQDHCGIESEVVAGVP 329


>gb|ABO26563.1| cathepsin B-like cysteine protease form 1 [Ixodes ricinus]
          Length = 337

 Score =  218 bits (554), Expect = 1e-53
 Identities = 111/258 (43%), Positives = 160/258 (62%), Gaps = 5/258 (1%)
 Frame = -3

Query: 894 LPRSYDVRQRFSNSSSVSHIRDQSFCGSCWAVSAASVLSDRLYIHSKGRYNFELSSRYIL 715
           LP S+D R+++S+ +S++ IRDQS CGSCWA  AA  +SDR+ IHS+G     +S+  +L
Sbjct: 85  LPESFDAREKWSHCASINLIRDQSTCGSCWAFGAAEAMSDRVCIHSEGGIQVNISAEDLL 144

Query: 714 SXXXXXXXXXXG-YLDSVWDFLEREGTVTGGEFQTDEGCQPYPLHPCGWPRKLACP---- 550
                      G Y  + W++ +  G V+ G + T +GC+PY L PC    K + P    
Sbjct: 145 DCCDSCGAGCDGGYPAAAWEYWKESGLVSDGLYGTPDGCKPYSLAPCEHHTKGSLPNCTG 204

Query: 549 WYLTPKCLKTKCDNEWYKTPTELHMYKVRESYYVGDFFGLFNEYYIRDEIFRNGPVQAGF 370
              TPKC+   C  + Y    +   +  ++ Y +       NE  I+ EIF+NGPV+A F
Sbjct: 205 TVPTPKCVHL-C-RKGYGKDYQHDKHFGKKVYSISS-----NEKQIQTEIFKNGPVEADF 257

Query: 369 YVYADFLAYKSGIYYHKKRSKLLGGHAVKIIGWGEEKGVKYWIIANSWGEEWGENGTFRM 190
            VYADFL+YKSG+Y H     +LGGHA++I+GWG E G  YW++ANSW E+WG++G F++
Sbjct: 258 TVYADFLSYKSGVYQHHS-GDVLGGHAIRILGWGTENGTPYWLVANSWNEDWGDHGYFKI 316

Query: 189 IRGKDNCGIEDEVYAGIP 136
           +RGKD CGIED++ AGIP
Sbjct: 317 LRGKDECGIEDDINAGIP 334


>gb|KHJ99394.1| papain family cysteine protease [Oesophagostomum dentatum]
          Length = 287

 Score =  217 bits (553), Expect = 2e-53
 Identities = 120/269 (44%), Positives = 150/269 (55%), Gaps = 8/269 (2%)
 Frame = -3

Query: 921 RPKLGVGTALPRSYDVRQRFSNSSSVSHIRDQSFCGSCWAVSAASVLSDRLYIHSKGRYN 742
           R +L +   +P S+D R ++   +S+  IRDQS CGSCWAVS AS +SDRL + S G+  
Sbjct: 24  RTELNINAVIPTSFDARVKWPACTSIKTIRDQSACGSCWAVSGASAMSDRLCVQSNGKIK 83

Query: 741 FELSSRYILSXXXXXXXXXXG--YLDSVWDFLEREGTVTGGEFQTDEGCQPYPLHPCGW- 571
             +S   IL+             Y    W F    G  TGG +     C+PYP HPCG  
Sbjct: 84  KFVSDADILACCGSFCGYGCKGGYTIRAWQFATSTGACTGGAYAQKGVCKPYPFHPCGQH 143

Query: 570 ---PRKLACP--WYLTPKCLKTKCDNEWYKTPTELHMYKVRESYYVGDFFGLFNEYYIRD 406
              P    CP   Y TP C K KC +  Y TP      + + SYYV           I+ 
Sbjct: 144 KGQPYYGNCPSSGYPTPACEK-KCQSG-YTTPYASDKLRAKSSYYVTSTVEA-----IQK 196

Query: 405 EIFRNGPVQAGFYVYADFLAYKSGIYYHKKRSKLLGGHAVKIIGWGEEKGVKYWIIANSW 226
           EI  NGPVQA F VYADF +YKSGIY H   ++  GGHA+KIIGWG +K V YW+I+NSW
Sbjct: 197 EIMTNGPVQASFSVYADFYSYKSGIYVHTAGARK-GGHAIKIIGWGVDKNVPYWLISNSW 255

Query: 225 GEEWGENGTFRMIRGKDNCGIEDEVYAGI 139
             +WGENG FR+ RGK+ CGIE  V AG+
Sbjct: 256 NSDWGENGLFRIARGKNECGIESRVVAGM 284


>ref|XP_013297560.1| papain family cysteine protease [Necator americanus]
           gi|568286612|gb|ETN75333.1| papain family cysteine
           protease [Necator americanus]
          Length = 335

 Score =  217 bits (553), Expect = 2e-53
 Identities = 121/275 (44%), Positives = 155/275 (56%), Gaps = 12/275 (4%)
 Frame = -3

Query: 927 QNRPKLGVGTALPRSYDVRQRFSNSSSVSHIRDQSFCGSCWAVSAASVLSDRLYIHSKGR 748
           ++R ++ +    P  +D R ++ +  S+  IRDQSFCGSCWAVSAA V+SDRL I S GR
Sbjct: 69  KDRKEVELDEEPPERFDARDKWPDCVSIGTIRDQSFCGSCWAVSAAEVMSDRLCIQSGGR 128

Query: 747 YNFELSSRYILSXXXXXXXXXXG--YLDSVWDFLEREGTVTGGEFQTDEGCQPYPLHPCG 574
              ELS   IL+             Y    W ++  +G  TGG ++    C+PY  HPCG
Sbjct: 129 IKLELSDTDILACCGFQCGSGCEGGYPLQAWRYVMEKGVCTGGRYRQKGVCKPYSFHPCG 188

Query: 573 W----------PRKLACPWYLTPKCLKTKCDNEWYKTPTELHMYKVRESYYVGDFFGLFN 424
           +          PRK     + TPKC   K     Y  P E   Y    +Y + +     +
Sbjct: 189 FKPGQTYYGDCPRKT----WETPKC--DKFCRRGYVKPYEKDKYYAISAYVLPN-----D 237

Query: 423 EYYIRDEIFRNGPVQAGFYVYADFLAYKSGIYYHKKRSKLLGGHAVKIIGWGEEKGVKYW 244
           E  IR EI +NGPVQA ++ Y DF  Y  GIY  +K  K  GGHAVKIIGWGEEKGVKYW
Sbjct: 238 EKAIRREIMKNGPVQAAYFTYEDFKLYDGGIYV-QKAGKRTGGHAVKIIGWGEEKGVKYW 296

Query: 243 IIANSWGEEWGENGTFRMIRGKDNCGIEDEVYAGI 139
           +IANSW   WGE G FRMIRG +NC +E+ +YAG+
Sbjct: 297 LIANSWNVLWGEEGYFRMIRGTNNCSLEEMIYAGM 331


>ref|XP_002635884.1| Hypothetical protein CBG01104 [Caenorhabditis briggsae]
           gi|187038246|emb|CAP22410.1| Protein CBG01104
           [Caenorhabditis briggsae]
          Length = 337

 Score =  217 bits (552), Expect = 2e-53
 Identities = 119/265 (44%), Positives = 153/265 (57%), Gaps = 10/265 (3%)
 Frame = -3

Query: 894 LPRSYDVRQRFSNSSSVSHIRDQSFCGSCWAVSAASVLSDRLYIHSKGRYNFELSSRYIL 715
           +P SYDVR  +S   SV +IRDQS CGSCWAV+AA  +SDRL I S G  N  +S+  +L
Sbjct: 78  IPESYDVRDHWSKCISVDNIRDQSDCGSCWAVAAAETISDRLCIASNGSINTFVSAEDLL 137

Query: 714 SXXXXXXXXXXG-YLDSVWDFLEREGTVTGGEFQTDEGCQPYPLHPCG-------WPRKL 559
           S          G Y    W +  ++G V+GG +++  GC+PY + PCG       WP+  
Sbjct: 138 SCCTSCGDGCDGGYPLQAWRYWVKQGLVSGGSYESQYGCKPYSIAPCGQTVNGVTWPK-- 195

Query: 558 ACPWY--LTPKCLKTKCDNEWYKTPTELHMYKVRESYYVGDFFGLFNEYYIRDEIFRNGP 385
            CP     TP+C         Y    E   +    +Y VG       E  I+ EI ++GP
Sbjct: 196 -CPAQEEATPECASHCTSKSSYSVAYEKDKHYGLSAYPVGR-----KEAQIQTEILQHGP 249

Query: 384 VQAGFYVYADFLAYKSGIYYHKKRSKLLGGHAVKIIGWGEEKGVKYWIIANSWGEEWGEN 205
           V+AGF VY+DF  YKSGIY H    +L GGHAVKI+GWG E G KYW++ANSW   WGE 
Sbjct: 250 VEAGFLVYSDFYRYKSGIYTHVSGQEL-GGHAVKILGWGVENGTKYWLVANSWNINWGEK 308

Query: 204 GTFRMIRGKDNCGIEDEVYAGIPAL 130
           G FR++RG++ CGIE  V AGIP L
Sbjct: 309 GYFRILRGRNECGIESAVVAGIPDL 333