BLASTX 2.2.25 [Feb-01-2011]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= Zingiber24_contig00039413
         (346 letters)

Database: ./nr 
           37,332,560 sequences; 13,225,080,153 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gb|EXB89943.1| hypothetical protein L484_023595 [Morus notabilis]     150   1e-34
ref|XP_004980096.1| PREDICTED: laccase-22-like [Setaria italica]      150   2e-34
ref|XP_006429309.1| hypothetical protein CICLE_v10011400mg [Citr...   150   2e-34
ref|XP_004147923.1| PREDICTED: laccase-4-like [Cucumis sativus] ...   149   3e-34
ref|XP_004163861.1| PREDICTED: laccase-4-like [Cucumis sativus]       149   4e-34
ref|XP_004137913.1| PREDICTED: laccase-4-like [Cucumis sativus]       149   4e-34
ref|XP_002533894.1| laccase, putative [Ricinus communis] gi|2235...   148   6e-34
ref|XP_006663136.1| PREDICTED: laccase-22-like [Oryza brachyantha]    148   8e-34
gb|EMJ06209.1| hypothetical protein PRUPE_ppa003646mg [Prunus pe...   148   8e-34
ref|XP_006411009.1| hypothetical protein EUTSA_v10016460mg [Eutr...   147   1e-33
ref|XP_004249084.1| PREDICTED: laccase-4-like [Solanum lycopersi...   147   1e-33
sp|Q0IQU1.2|LAC22_ORYSJ RecName: Full=Laccase-22; AltName: Full=...   147   2e-33
ref|XP_002278638.1| PREDICTED: laccase-4 [Vitis vinifera] gi|297...   147   2e-33
ref|XP_006293932.1| hypothetical protein CARUB_v10022927mg [Caps...   146   3e-33
ref|XP_004302643.1| PREDICTED: laccase-4-like [Fragaria vesca su...   145   4e-33
ref|XP_004294236.1| PREDICTED: laccase-4-like [Fragaria vesca su...   145   4e-33
ref|XP_006349470.1| PREDICTED: laccase-4-like [Solanum tuberosum]     145   5e-33
gb|EOY07284.1| Laccase/Diphenol oxidase family protein isoform 2...   145   5e-33
gb|EOY07283.1| Laccase/Diphenol oxidase family protein isoform 1...   145   5e-33
ref|XP_002879726.1| IRX12/LAC4 [Arabidopsis lyrata subsp. lyrata...   145   5e-33

>gb|EXB89943.1| hypothetical protein L484_023595 [Morus notabilis]
          Length = 558

 Score =  150 bits (380), Expect = 1e-34
 Identities = 74/101 (73%), Positives = 88/101 (87%)
 Frame = +1

Query: 4   GFTLAVEKGKKYLLRVINAALNEDLFFKVAGHRMTVVEVDAAYTKPFSIDTILLAPGQTT 183
           GFTL V+ GK YLLR+INAALNE+LFFK+AGH++TVVEVDA Y KPFSIDTI++APGQTT
Sbjct: 208 GFTLPVQTGKTYLLRIINAALNEELFFKIAGHKLTVVEVDATYVKPFSIDTIVIAPGQTT 267

Query: 184 NVLLTADKTAGGRYLVTTSPFADSPLVAVDNRTATATLHYA 306
           N L+TAD+ + G+YLV  SPF D+P +AVDN TATATLHYA
Sbjct: 268 NALITADQNS-GKYLVAASPFMDAP-IAVDNATATATLHYA 306


>ref|XP_004980096.1| PREDICTED: laccase-22-like [Setaria italica]
          Length = 589

 Score =  150 bits (379), Expect = 2e-34
 Identities = 74/105 (70%), Positives = 88/105 (83%)
 Frame = +1

Query: 1   DGFTLAVEKGKKYLLRVINAALNEDLFFKVAGHRMTVVEVDAAYTKPFSIDTILLAPGQT 180
           DGF L VE GK Y+LR+INAALN+DLFFK+AGH+ TVVEVDA YTKPF   T+L+ PGQT
Sbjct: 239 DGFKLNVENGKTYMLRIINAALNDDLFFKIAGHKFTVVEVDAVYTKPFKTATLLITPGQT 298

Query: 181 TNVLLTADKTAGGRYLVTTSPFADSPLVAVDNRTATATLHYADIV 315
           TNVLLTAD+TA GRYL++ SPF D+P V VDN+T TATLHYA+ +
Sbjct: 299 TNVLLTADRTA-GRYLLSVSPFMDAP-VQVDNKTGTATLHYANTI 341


>ref|XP_006429309.1| hypothetical protein CICLE_v10011400mg [Citrus clementina]
           gi|568854725|ref|XP_006480970.1| PREDICTED:
           laccase-4-like [Citrus sinensis]
           gi|557531366|gb|ESR42549.1| hypothetical protein
           CICLE_v10011400mg [Citrus clementina]
          Length = 555

 Score =  150 bits (378), Expect = 2e-34
 Identities = 73/101 (72%), Positives = 88/101 (87%)
 Frame = +1

Query: 4   GFTLAVEKGKKYLLRVINAALNEDLFFKVAGHRMTVVEVDAAYTKPFSIDTILLAPGQTT 183
           GFTL V+ GK Y+LR+INAALNE+LFFK+AGH++TVVEVDA Y KPF  DTI++APGQTT
Sbjct: 206 GFTLPVDSGKTYMLRIINAALNEELFFKIAGHKLTVVEVDATYVKPFKTDTIVIAPGQTT 265

Query: 184 NVLLTADKTAGGRYLVTTSPFADSPLVAVDNRTATATLHYA 306
           NVLL+ADKT+ G+YLV  SPF D+P +AVDN TATATLHY+
Sbjct: 266 NVLLSADKTS-GKYLVAASPFMDAP-IAVDNATATATLHYS 304


>ref|XP_004147923.1| PREDICTED: laccase-4-like [Cucumis sativus]
           gi|449516581|ref|XP_004165325.1| PREDICTED:
           laccase-4-like [Cucumis sativus]
          Length = 556

 Score =  149 bits (377), Expect = 3e-34
 Identities = 74/101 (73%), Positives = 86/101 (85%)
 Frame = +1

Query: 4   GFTLAVEKGKKYLLRVINAALNEDLFFKVAGHRMTVVEVDAAYTKPFSIDTILLAPGQTT 183
           GFTL V+ G  YLLR+INAALNE+LFFK+AGH++TVVEVDA Y KPF  DTIL+APGQTT
Sbjct: 206 GFTLPVKSGHTYLLRIINAALNEELFFKIAGHKLTVVEVDATYVKPFKTDTILIAPGQTT 265

Query: 184 NVLLTADKTAGGRYLVTTSPFADSPLVAVDNRTATATLHYA 306
           N L+TAD+T+ G+YLV  SPF DSP +AVDN TATATLHYA
Sbjct: 266 NALITADQTS-GKYLVAASPFMDSP-IAVDNNTATATLHYA 304


>ref|XP_004163861.1| PREDICTED: laccase-4-like [Cucumis sativus]
          Length = 559

 Score =  149 bits (376), Expect = 4e-34
 Identities = 73/100 (73%), Positives = 88/100 (88%)
 Frame = +1

Query: 4   GFTLAVEKGKKYLLRVINAALNEDLFFKVAGHRMTVVEVDAAYTKPFSIDTILLAPGQTT 183
           GFTL V+KGK YLLR+INAALNE+LFFKVAGH++TVVEVDA Y KPF  DT+L+APGQTT
Sbjct: 209 GFTLPVQKGKTYLLRIINAALNEELFFKVAGHKLTVVEVDATYVKPFKTDTVLIAPGQTT 268

Query: 184 NVLLTADKTAGGRYLVTTSPFADSPLVAVDNRTATATLHY 303
           NVLLTA++ + G+Y+V  SPF D+P VAVDN+TATAT+HY
Sbjct: 269 NVLLTANQNS-GKYMVAVSPFMDAP-VAVDNKTATATVHY 306


>ref|XP_004137913.1| PREDICTED: laccase-4-like [Cucumis sativus]
          Length = 559

 Score =  149 bits (376), Expect = 4e-34
 Identities = 73/100 (73%), Positives = 88/100 (88%)
 Frame = +1

Query: 4   GFTLAVEKGKKYLLRVINAALNEDLFFKVAGHRMTVVEVDAAYTKPFSIDTILLAPGQTT 183
           GFTL V+KGK YLLR+INAALNE+LFFKVAGH++TVVEVDA Y KPF  DT+L+APGQTT
Sbjct: 209 GFTLPVQKGKTYLLRIINAALNEELFFKVAGHKLTVVEVDATYVKPFKTDTVLIAPGQTT 268

Query: 184 NVLLTADKTAGGRYLVTTSPFADSPLVAVDNRTATATLHY 303
           NVLLTA++ + G+Y+V  SPF D+P VAVDN+TATAT+HY
Sbjct: 269 NVLLTANQNS-GKYMVAVSPFMDAP-VAVDNKTATATVHY 306


>ref|XP_002533894.1| laccase, putative [Ricinus communis] gi|223526158|gb|EEF28494.1|
           laccase, putative [Ricinus communis]
          Length = 556

 Score =  148 bits (374), Expect = 6e-34
 Identities = 74/101 (73%), Positives = 87/101 (86%)
 Frame = +1

Query: 4   GFTLAVEKGKKYLLRVINAALNEDLFFKVAGHRMTVVEVDAAYTKPFSIDTILLAPGQTT 183
           GF L VE GK YLLR+INAALNE+LFFK+AGH++TVVE+DA Y KP   DT+LLAPGQTT
Sbjct: 206 GFRLPVESGKAYLLRLINAALNEELFFKIAGHQLTVVEIDACYVKPLKTDTVLLAPGQTT 265

Query: 184 NVLLTADKTAGGRYLVTTSPFADSPLVAVDNRTATATLHYA 306
           NVL+TA+K + G+YLVT SPF D+P VAVDNRTATATLHY+
Sbjct: 266 NVLVTANKNS-GKYLVTASPFMDAP-VAVDNRTATATLHYS 304


>ref|XP_006663136.1| PREDICTED: laccase-22-like [Oryza brachyantha]
          Length = 566

 Score =  148 bits (373), Expect = 8e-34
 Identities = 74/105 (70%), Positives = 89/105 (84%)
 Frame = +1

Query: 1   DGFTLAVEKGKKYLLRVINAALNEDLFFKVAGHRMTVVEVDAAYTKPFSIDTILLAPGQT 180
           DGF L VE GK Y+LR+INAALN+DLFFKVAGH +TVVEVDA YTKPF+ DT+L+ PGQT
Sbjct: 214 DGFKLKVENGKTYMLRIINAALNDDLFFKVAGHELTVVEVDAVYTKPFTTDTLLITPGQT 273

Query: 181 TNVLLTADKTAGGRYLVTTSPFADSPLVAVDNRTATATLHYADIV 315
           T+VLL A+++A GRYL++ SPF DSPL  VDN+T TATLHYA+ V
Sbjct: 274 TSVLLRANQSA-GRYLLSVSPFMDSPL-QVDNKTGTATLHYANTV 316


>gb|EMJ06209.1| hypothetical protein PRUPE_ppa003646mg [Prunus persica]
          Length = 559

 Score =  148 bits (373), Expect = 8e-34
 Identities = 72/101 (71%), Positives = 87/101 (86%)
 Frame = +1

Query: 4   GFTLAVEKGKKYLLRVINAALNEDLFFKVAGHRMTVVEVDAAYTKPFSIDTILLAPGQTT 183
           GFTL VEKGK YLLR+INAALNE+LFFK+AGH++T+VEVDA Y KPF  DTI++APGQTT
Sbjct: 207 GFTLPVEKGKTYLLRIINAALNEELFFKIAGHKLTIVEVDATYVKPFKTDTIVIAPGQTT 266

Query: 184 NVLLTADKTAGGRYLVTTSPFADSPLVAVDNRTATATLHYA 306
           N L+TA++ + G+YLV  SPF DSP +AVDN TATATLHY+
Sbjct: 267 NALITANQNS-GKYLVAASPFMDSP-IAVDNLTATATLHYS 305


>ref|XP_006411009.1| hypothetical protein EUTSA_v10016460mg [Eutrema salsugineum]
           gi|557112178|gb|ESQ52462.1| hypothetical protein
           EUTSA_v10016460mg [Eutrema salsugineum]
          Length = 557

 Score =  147 bits (372), Expect = 1e-33
 Identities = 75/101 (74%), Positives = 87/101 (86%)
 Frame = +1

Query: 4   GFTLAVEKGKKYLLRVINAALNEDLFFKVAGHRMTVVEVDAAYTKPFSIDTILLAPGQTT 183
           G+ L+VE GK YLLR++NAALNE+LFFKVAGH  TVVEVDA Y KPF IDT+L+APGQTT
Sbjct: 207 GYKLSVENGKTYLLRLVNAALNEELFFKVAGHIFTVVEVDAVYVKPFKIDTVLIAPGQTT 266

Query: 184 NVLLTADKTAGGRYLVTTSPFADSPLVAVDNRTATATLHYA 306
           NVLLTA K+A G+YLVT SPF D+P VAVDN TATAT+HY+
Sbjct: 267 NVLLTASKSA-GKYLVTASPFMDAP-VAVDNVTATATVHYS 305


>ref|XP_004249084.1| PREDICTED: laccase-4-like [Solanum lycopersicum]
          Length = 556

 Score =  147 bits (371), Expect = 1e-33
 Identities = 71/101 (70%), Positives = 87/101 (86%)
 Frame = +1

Query: 4   GFTLAVEKGKKYLLRVINAALNEDLFFKVAGHRMTVVEVDAAYTKPFSIDTILLAPGQTT 183
           G+TL+V+ GK Y+LRVINAALNE+LFFK+AGH+MTVVEVDA Y KPF  DTI++APGQTT
Sbjct: 206 GYTLSVDPGKSYMLRVINAALNEELFFKIAGHKMTVVEVDATYVKPFKTDTIIIAPGQTT 265

Query: 184 NVLLTADKTAGGRYLVTTSPFADSPLVAVDNRTATATLHYA 306
           NV++TADK   G+Y+V  SPF D+P +AVDN TATATLHY+
Sbjct: 266 NVIVTADK-GSGKYMVAASPFMDAP-IAVDNVTATATLHYS 304


>sp|Q0IQU1.2|LAC22_ORYSJ RecName: Full=Laccase-22; AltName: Full=Benzenediol:oxygen
           oxidoreductase 22; AltName: Full=Diphenol oxidase 22;
           AltName: Full=Urishiol oxidase 22; Flags: Precursor
           gi|62733306|gb|AAX95423.1| laccase (EC 1.10.3.2)
           precursor - common tobacco [Oryza sativa Japonica Group]
           gi|77552735|gb|ABA95532.1| Multicopper oxidase family
           protein, expressed [Oryza sativa Japonica Group]
           gi|125578117|gb|EAZ19339.1| hypothetical protein
           OsJ_34890 [Oryza sativa Japonica Group]
          Length = 564

 Score =  147 bits (370), Expect = 2e-33
 Identities = 73/105 (69%), Positives = 88/105 (83%)
 Frame = +1

Query: 1   DGFTLAVEKGKKYLLRVINAALNEDLFFKVAGHRMTVVEVDAAYTKPFSIDTILLAPGQT 180
           DGF L+VE GK Y+LR+INAALN+DLFFKVAGH +TVVEVDA YTKPF  DT+L+ PGQT
Sbjct: 213 DGFKLSVENGKTYMLRIINAALNDDLFFKVAGHELTVVEVDAVYTKPFKTDTLLITPGQT 272

Query: 181 TNVLLTADKTAGGRYLVTTSPFADSPLVAVDNRTATATLHYADIV 315
           TNVL+ A++ A GRYL++ SPF D+P V VDN+T TATLHYA+ V
Sbjct: 273 TNVLVRANQGA-GRYLLSVSPFMDAP-VQVDNKTGTATLHYANTV 315


>ref|XP_002278638.1| PREDICTED: laccase-4 [Vitis vinifera] gi|297740241|emb|CBI30423.3|
           unnamed protein product [Vitis vinifera]
          Length = 556

 Score =  147 bits (370), Expect = 2e-33
 Identities = 71/101 (70%), Positives = 89/101 (88%)
 Frame = +1

Query: 4   GFTLAVEKGKKYLLRVINAALNEDLFFKVAGHRMTVVEVDAAYTKPFSIDTILLAPGQTT 183
           GF+L VE GK YLLR+INAALNE+LFFK+AGH+++VVEVDA YTKPF IDT+++APGQTT
Sbjct: 207 GFSLQVEAGKTYLLRIINAALNEELFFKIAGHQLSVVEVDAVYTKPFKIDTLVIAPGQTT 266

Query: 184 NVLLTADKTAGGRYLVTTSPFADSPLVAVDNRTATATLHYA 306
           N L+TAD+++ G+YL+  SPF DSP +AVDN TATATLHY+
Sbjct: 267 NALITADQSS-GKYLMAASPFMDSP-IAVDNLTATATLHYS 305


>ref|XP_006293932.1| hypothetical protein CARUB_v10022927mg [Capsella rubella]
           gi|482562640|gb|EOA26830.1| hypothetical protein
           CARUB_v10022927mg [Capsella rubella]
          Length = 558

 Score =  146 bits (368), Expect = 3e-33
 Identities = 74/101 (73%), Positives = 87/101 (86%)
 Frame = +1

Query: 4   GFTLAVEKGKKYLLRVINAALNEDLFFKVAGHRMTVVEVDAAYTKPFSIDTILLAPGQTT 183
           G+ L+VE GK YLLR+INAALNE+LFFKVAGH  TVVEVDA Y KPF IDT+L+APGQTT
Sbjct: 208 GYKLSVENGKTYLLRLINAALNEELFFKVAGHIFTVVEVDAVYVKPFKIDTVLIAPGQTT 267

Query: 184 NVLLTADKTAGGRYLVTTSPFADSPLVAVDNRTATATLHYA 306
           NVLLTA K+A G++LVT SPF D+P +AVDN TATAT+HY+
Sbjct: 268 NVLLTASKSA-GKFLVTASPFMDAP-IAVDNVTATATVHYS 306


>ref|XP_004302643.1| PREDICTED: laccase-4-like [Fragaria vesca subsp. vesca]
          Length = 561

 Score =  145 bits (367), Expect = 4e-33
 Identities = 68/101 (67%), Positives = 87/101 (86%)
 Frame = +1

Query: 4   GFTLAVEKGKKYLLRVINAALNEDLFFKVAGHRMTVVEVDAAYTKPFSIDTILLAPGQTT 183
           GF L+VE GK YLLR+INAALNE+LFFK+AGH++T+VEVDA Y KPF  DTI++APGQTT
Sbjct: 208 GFKLSVESGKTYLLRIINAALNEELFFKIAGHKLTIVEVDATYVKPFKTDTIVIAPGQTT 267

Query: 184 NVLLTADKTAGGRYLVTTSPFADSPLVAVDNRTATATLHYA 306
           N L+TA++ + G+YLVT SPF D+P +AVDN T+TAT+HY+
Sbjct: 268 NALITANQKS-GKYLVTASPFLDTPGIAVDNLTSTATVHYS 307


>ref|XP_004294236.1| PREDICTED: laccase-4-like [Fragaria vesca subsp. vesca]
          Length = 561

 Score =  145 bits (367), Expect = 4e-33
 Identities = 71/100 (71%), Positives = 84/100 (84%)
 Frame = +1

Query: 4   GFTLAVEKGKKYLLRVINAALNEDLFFKVAGHRMTVVEVDAAYTKPFSIDTILLAPGQTT 183
           G+ L V+ G  YLLR+INAALN++LFFKVA H++TVVEVDA YTKPF   TIL+APGQTT
Sbjct: 211 GYKLPVQPGHTYLLRIINAALNDELFFKVANHKLTVVEVDAVYTKPFETTTILIAPGQTT 270

Query: 184 NVLLTADKTAGGRYLVTTSPFADSPLVAVDNRTATATLHY 303
           NVLLTAD++  G+YLV  SPF D+P VAVDN+TATATLHY
Sbjct: 271 NVLLTADRST-GKYLVAASPFMDNPTVAVDNKTATATLHY 309


>ref|XP_006349470.1| PREDICTED: laccase-4-like [Solanum tuberosum]
          Length = 556

 Score =  145 bits (366), Expect = 5e-33
 Identities = 70/101 (69%), Positives = 87/101 (86%)
 Frame = +1

Query: 4   GFTLAVEKGKKYLLRVINAALNEDLFFKVAGHRMTVVEVDAAYTKPFSIDTILLAPGQTT 183
           G+TL+V+ GK Y+LRVINAALNE+LFFK+AGH+MTVVEVDA Y KPF  DTI++APGQTT
Sbjct: 206 GYTLSVDPGKSYMLRVINAALNEELFFKIAGHKMTVVEVDATYVKPFKTDTIIIAPGQTT 265

Query: 184 NVLLTADKTAGGRYLVTTSPFADSPLVAVDNRTATATLHYA 306
           NV++TA+K   G+Y+V  SPF D+P +AVDN TATATLHY+
Sbjct: 266 NVIVTANK-GSGKYMVAASPFMDAP-IAVDNVTATATLHYS 304


>gb|EOY07284.1| Laccase/Diphenol oxidase family protein isoform 2 [Theobroma cacao]
          Length = 490

 Score =  145 bits (366), Expect = 5e-33
 Identities = 71/101 (70%), Positives = 87/101 (86%)
 Frame = +1

Query: 4   GFTLAVEKGKKYLLRVINAALNEDLFFKVAGHRMTVVEVDAAYTKPFSIDTILLAPGQTT 183
           GFTL VE GK YLLR+INAALNE+LFFK+AGH++TVVEVDA Y KPF   T+++APGQTT
Sbjct: 140 GFTLPVENGKTYLLRLINAALNEELFFKIAGHKLTVVEVDATYVKPFKTKTVIIAPGQTT 199

Query: 184 NVLLTADKTAGGRYLVTTSPFADSPLVAVDNRTATATLHYA 306
           NVL++ADK++ G+YLV  SPF D+P +AVDN TATATLHY+
Sbjct: 200 NVLVSADKSS-GKYLVAASPFMDAP-IAVDNLTATATLHYS 238


>gb|EOY07283.1| Laccase/Diphenol oxidase family protein isoform 1 [Theobroma cacao]
          Length = 556

 Score =  145 bits (366), Expect = 5e-33
 Identities = 71/101 (70%), Positives = 87/101 (86%)
 Frame = +1

Query: 4   GFTLAVEKGKKYLLRVINAALNEDLFFKVAGHRMTVVEVDAAYTKPFSIDTILLAPGQTT 183
           GFTL VE GK YLLR+INAALNE+LFFK+AGH++TVVEVDA Y KPF   T+++APGQTT
Sbjct: 206 GFTLPVENGKTYLLRLINAALNEELFFKIAGHKLTVVEVDATYVKPFKTKTVIIAPGQTT 265

Query: 184 NVLLTADKTAGGRYLVTTSPFADSPLVAVDNRTATATLHYA 306
           NVL++ADK++ G+YLV  SPF D+P +AVDN TATATLHY+
Sbjct: 266 NVLVSADKSS-GKYLVAASPFMDAP-IAVDNLTATATLHYS 304


>ref|XP_002879726.1| IRX12/LAC4 [Arabidopsis lyrata subsp. lyrata]
           gi|297325565|gb|EFH55985.1| IRX12/LAC4 [Arabidopsis
           lyrata subsp. lyrata]
          Length = 557

 Score =  145 bits (366), Expect = 5e-33
 Identities = 73/101 (72%), Positives = 86/101 (85%)
 Frame = +1

Query: 4   GFTLAVEKGKKYLLRVINAALNEDLFFKVAGHRMTVVEVDAAYTKPFSIDTILLAPGQTT 183
           G+ L+VE GK YLLR++NAALNE+LFFKVAGH  TVVEVDA Y KPF  DT+L+APGQTT
Sbjct: 207 GYKLSVENGKTYLLRLVNAALNEELFFKVAGHIFTVVEVDAVYVKPFKTDTVLIAPGQTT 266

Query: 184 NVLLTADKTAGGRYLVTTSPFADSPLVAVDNRTATATLHYA 306
           NVLLTA K+A G+YLVT SPF D+P +AVDN TATAT+HY+
Sbjct: 267 NVLLTASKSA-GKYLVTASPFMDAP-IAVDNVTATATVHYS 305