BLASTX nr result
ID: Zingiber24_contig00026427
seq
BLASTX 2.2.25 [Feb-01-2011]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Zingiber24_contig00026427
(358 letters)
Database: ./nr
37,332,560 sequences; 13,225,080,153 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gb|EOY25692.1| FAD-binding Berberine family protein, putative [T... 125 8e-27
gb|EMJ23683.1| hypothetical protein PRUPE_ppa004103mg [Prunus pe... 125 8e-27
gb|EMJ14197.1| hypothetical protein PRUPE_ppa022785mg [Prunus pe... 125 8e-27
gb|EMJ14108.1| hypothetical protein PRUPE_ppa022216mg [Prunus pe... 125 8e-27
gb|EMJ13590.1| hypothetical protein PRUPE_ppa016294mg [Prunus pe... 125 8e-27
gb|EOY19471.1| FAD-binding Berberine family protein [Theobroma c... 122 4e-26
gb|EMJ14555.1| hypothetical protein PRUPE_ppa027050mg [Prunus pe... 122 4e-26
gb|ADY15026.1| (S)-tetrahydroprotoberberine oxidase [Berberis wi... 122 4e-26
ref|XP_006490201.1| PREDICTED: tetrahydrocannabinolic acid synth... 122 6e-26
gb|ESW19445.1| hypothetical protein PHAVU_006G125800g [Phaseolus... 121 1e-25
gb|AGL44332.1| FAD-dependent oxidoreductase, partial [Papaver so... 121 1e-25
ref|XP_003546280.1| PREDICTED: inactive tetrahydrocannabinolic a... 121 1e-25
ref|XP_003535119.1| PREDICTED: cannabidiolic acid synthase-like ... 121 1e-25
ref|XP_004134554.1| PREDICTED: reticuline oxidase-like protein-l... 120 2e-25
ref|XP_006468345.1| PREDICTED: reticuline oxidase-like protein-l... 119 3e-25
ref|XP_006448862.1| hypothetical protein CICLE_v10014829mg [Citr... 119 3e-25
gb|EMJ13559.1| hypothetical protein PRUPE_ppa014683mg [Prunus pe... 119 3e-25
ref|XP_003531073.1| PREDICTED: tetrahydrocannabinolic acid synth... 119 3e-25
ref|XP_003524780.1| PREDICTED: tetrahydrocannabinolic acid synth... 119 3e-25
ref|XP_003531072.2| PREDICTED: reticuline oxidase-like protein-l... 119 5e-25
>gb|EOY25692.1| FAD-binding Berberine family protein, putative [Theobroma cacao]
Length = 538
Score = 125 bits (313), Expect = 8e-27
Identities = 63/119 (52%), Positives = 79/119 (66%)
Frame = -2
Query: 357 FPAGICSTVXXXXXXXXXXXXSLQRKYGVSADNIVDAKLVNAEGELLTRETMEEDLFWAI 178
FPAGICS++ +L RK+G++ADNIVDA LVNA+G +L R M EDLFWAI
Sbjct: 172 FPAGICSSIGVGGHLSGGGQGTLMRKFGLAADNIVDAILVNADGNILDRRAMGEDLFWAI 231
Query: 177 RXXXXXXXXXXXAYKLRLVPVPPKVTVFSVTRTLGQGATRLLHSWQSIAPRLADDLWLR 1
R +K++LVPVPPKVT F+V TL QGAT L+H WQ IA RL +DL++R
Sbjct: 232 RGGGAASFGVIVEWKVKLVPVPPKVTAFNVPITLQQGATSLIHRWQQIATRLPEDLFIR 290
>gb|EMJ23683.1| hypothetical protein PRUPE_ppa004103mg [Prunus persica]
Length = 530
Score = 125 bits (313), Expect = 8e-27
Identities = 61/119 (51%), Positives = 81/119 (68%)
Frame = -2
Query: 357 FPAGICSTVXXXXXXXXXXXXSLQRKYGVSADNIVDAKLVNAEGELLTRETMEEDLFWAI 178
FPAGIC TV L RKYG+S DNIVDA+LV A G +L R++M EDLFWAI
Sbjct: 170 FPAGICPTVGAGGHFSGGGYGFLMRKYGLSVDNIVDARLVTANGRILDRKSMGEDLFWAI 229
Query: 177 RXXXXXXXXXXXAYKLRLVPVPPKVTVFSVTRTLGQGATRLLHSWQSIAPRLADDLWLR 1
R ++KL+LVPVPPKVTVF++T+T+ +G T L++ WQ++AP+L D++LR
Sbjct: 230 RGGGGASFGVILSWKLKLVPVPPKVTVFNLTKTIEEGVTDLVYKWQTLAPQLPKDVFLR 288
>gb|EMJ14197.1| hypothetical protein PRUPE_ppa022785mg [Prunus persica]
Length = 527
Score = 125 bits (313), Expect = 8e-27
Identities = 59/119 (49%), Positives = 82/119 (68%)
Frame = -2
Query: 357 FPAGICSTVXXXXXXXXXXXXSLQRKYGVSADNIVDAKLVNAEGELLTRETMEEDLFWAI 178
FPAG+C TV + RKYG+S DN+VDAK+V +G++L R++M EDLFWAI
Sbjct: 167 FPAGLCPTVGAGGHISGGGYGVMMRKYGLSVDNVVDAKIVTVKGQILDRKSMGEDLFWAI 226
Query: 177 RXXXXXXXXXXXAYKLRLVPVPPKVTVFSVTRTLGQGATRLLHSWQSIAPRLADDLWLR 1
R ++KL+LVPVP KVTVF+VT+T+ +GAT L++ WQ++AP L +DL+LR
Sbjct: 227 RGGGGASFGVILSWKLKLVPVPSKVTVFNVTKTIEEGATDLVYKWQTVAPELPEDLFLR 285
>gb|EMJ14108.1| hypothetical protein PRUPE_ppa022216mg [Prunus persica]
Length = 530
Score = 125 bits (313), Expect = 8e-27
Identities = 61/119 (51%), Positives = 81/119 (68%)
Frame = -2
Query: 357 FPAGICSTVXXXXXXXXXXXXSLQRKYGVSADNIVDAKLVNAEGELLTRETMEEDLFWAI 178
FPAGIC TV L RKYG+S DNIVDA+LV A G +L R++M EDLFWAI
Sbjct: 170 FPAGICPTVGAGGHFSGGGYGFLMRKYGLSVDNIVDARLVTANGRILDRKSMGEDLFWAI 229
Query: 177 RXXXXXXXXXXXAYKLRLVPVPPKVTVFSVTRTLGQGATRLLHSWQSIAPRLADDLWLR 1
R ++KL+LVPVPPKVTVF++T+T+ +G T L++ WQ++AP+L D++LR
Sbjct: 230 RGGGGASFGVILSWKLKLVPVPPKVTVFNLTKTIEEGVTDLVYKWQTLAPQLPKDVFLR 288
>gb|EMJ13590.1| hypothetical protein PRUPE_ppa016294mg [Prunus persica]
Length = 530
Score = 125 bits (313), Expect = 8e-27
Identities = 61/119 (51%), Positives = 81/119 (68%)
Frame = -2
Query: 357 FPAGICSTVXXXXXXXXXXXXSLQRKYGVSADNIVDAKLVNAEGELLTRETMEEDLFWAI 178
FPAGIC TV L RKYG+S DNIVDA+LV A G +L R++M EDLFWAI
Sbjct: 170 FPAGICPTVGAGGHFSGGGYGFLMRKYGLSVDNIVDARLVTANGRILDRKSMGEDLFWAI 229
Query: 177 RXXXXXXXXXXXAYKLRLVPVPPKVTVFSVTRTLGQGATRLLHSWQSIAPRLADDLWLR 1
R ++KL+LVPVPPKVTVF++T+T+ +G T L++ WQ++AP+L D++LR
Sbjct: 230 RGGGGASFGVILSWKLKLVPVPPKVTVFNLTKTIEEGVTDLVYKWQTLAPQLPKDVFLR 288
>gb|EOY19471.1| FAD-binding Berberine family protein [Theobroma cacao]
Length = 576
Score = 122 bits (307), Expect = 4e-26
Identities = 61/118 (51%), Positives = 79/118 (66%)
Frame = -2
Query: 357 FPAGICSTVXXXXXXXXXXXXSLQRKYGVSADNIVDAKLVNAEGELLTRETMEEDLFWAI 178
FPAGIC TV L RKYG++ADNI+DA+L++A G +L R++M EDLFWAI
Sbjct: 212 FPAGICHTVGVGGHFSGGGYGGLFRKYGLAADNIIDAQLIDANGRILDRQSMGEDLFWAI 271
Query: 177 RXXXXXXXXXXXAYKLRLVPVPPKVTVFSVTRTLGQGATRLLHSWQSIAPRLADDLWL 4
R A+KL+LVPVP VTVFS+T+TL Q AT L+H WQ +A +L DD++L
Sbjct: 272 RGGGGGSYGIVLAWKLKLVPVPATVTVFSITKTLEQNATELIHRWQDVAHKLPDDIFL 329
>gb|EMJ14555.1| hypothetical protein PRUPE_ppa027050mg [Prunus persica]
Length = 519
Score = 122 bits (307), Expect = 4e-26
Identities = 60/119 (50%), Positives = 81/119 (68%)
Frame = -2
Query: 357 FPAGICSTVXXXXXXXXXXXXSLQRKYGVSADNIVDAKLVNAEGELLTRETMEEDLFWAI 178
FPAGIC TV + RKYG+S DNIVDAK+V +G +L R++M EDLFWAI
Sbjct: 170 FPAGICPTVGAGGHFGGGGYGFMMRKYGLSVDNIVDAKIVTVKGTILDRKSMGEDLFWAI 229
Query: 177 RXXXXXXXXXXXAYKLRLVPVPPKVTVFSVTRTLGQGATRLLHSWQSIAPRLADDLWLR 1
R ++KL+LVPVP KVTVF+VT+T+ +GAT L++ WQ++AP+L +L+LR
Sbjct: 230 RGGGGASFGVILSWKLQLVPVPAKVTVFNVTKTIEEGATDLVYKWQTVAPKLPKELFLR 288
>gb|ADY15026.1| (S)-tetrahydroprotoberberine oxidase [Berberis wilsonae]
Length = 530
Score = 122 bits (307), Expect = 4e-26
Identities = 60/118 (50%), Positives = 78/118 (66%)
Frame = -2
Query: 357 FPAGICSTVXXXXXXXXXXXXSLQRKYGVSADNIVDAKLVNAEGELLTRETMEEDLFWAI 178
FPAG+C TV L RKYGVSAD+++DA++VN +GE+L RE+M EDLFWAI
Sbjct: 166 FPAGLCPTVGVGGHISGAGYGVLMRKYGVSADHVIDARIVNVDGEILDRESMGEDLFWAI 225
Query: 177 RXXXXXXXXXXXAYKLRLVPVPPKVTVFSVTRTLGQGATRLLHSWQSIAPRLADDLWL 4
R A+K+RLVPVPP VT+F V +TL +GAT LLH WQ I + +DL++
Sbjct: 226 RGGGGASFGVILAWKIRLVPVPPTVTIFIVPKTLEEGATALLHKWQFIGDNVHEDLFI 283
>ref|XP_006490201.1| PREDICTED: tetrahydrocannabinolic acid synthase-like [Citrus
sinensis]
Length = 536
Score = 122 bits (305), Expect = 6e-26
Identities = 59/119 (49%), Positives = 81/119 (68%)
Frame = -2
Query: 357 FPAGICSTVXXXXXXXXXXXXSLQRKYGVSADNIVDAKLVNAEGELLTRETMEEDLFWAI 178
FPAG+C+++ S+ RKYG+ ADN+VDA++V+A G +L RE M ED FWAI
Sbjct: 169 FPAGLCTSLGVGGHITGGAYGSMMRKYGLGADNVVDARIVDASGRILDREAMGEDFFWAI 228
Query: 177 RXXXXXXXXXXXAYKLRLVPVPPKVTVFSVTRTLGQGATRLLHSWQSIAPRLADDLWLR 1
R A+K++LVPVP VTVF+VT+TL QGAT+LLH WQ +A +L +DL++R
Sbjct: 229 RGGGGASFGVILAWKIKLVPVPATVTVFTVTKTLEQGATKLLHRWQEVADKLDEDLFIR 287
>gb|ESW19445.1| hypothetical protein PHAVU_006G125800g [Phaseolus vulgaris]
Length = 543
Score = 121 bits (303), Expect = 1e-25
Identities = 57/119 (47%), Positives = 81/119 (68%)
Frame = -2
Query: 357 FPAGICSTVXXXXXXXXXXXXSLQRKYGVSADNIVDAKLVNAEGELLTRETMEEDLFWAI 178
FPAG+C+++ S+ RKYG+ ADN++DAKLV+A G++L RE M EDLFWAI
Sbjct: 168 FPAGLCTSLGVGGHITGGAYGSMMRKYGLGADNVLDAKLVDANGQILDREAMGEDLFWAI 227
Query: 177 RXXXXXXXXXXXAYKLRLVPVPPKVTVFSVTRTLGQGATRLLHSWQSIAPRLADDLWLR 1
R +K++LVPVP VTVF+VTR+L Q AT+++H WQ +AP + +DL++R
Sbjct: 228 RGGGGASFGILLWWKIKLVPVPENVTVFTVTRSLEQDATKIVHRWQEVAPYIDEDLFIR 286
>gb|AGL44332.1| FAD-dependent oxidoreductase, partial [Papaver somniferum]
Length = 535
Score = 121 bits (303), Expect = 1e-25
Identities = 54/119 (45%), Positives = 82/119 (68%)
Frame = -2
Query: 357 FPAGICSTVXXXXXXXXXXXXSLQRKYGVSADNIVDAKLVNAEGELLTRETMEEDLFWAI 178
FPA +C+TV SL RKYGV+ DN++D ++V+A G++L ++TM EDLFWAI
Sbjct: 167 FPAAVCTTVGVGGQFSGGGYGSLLRKYGVAGDNVIDVRIVDAHGQILNKDTMGEDLFWAI 226
Query: 177 RXXXXXXXXXXXAYKLRLVPVPPKVTVFSVTRTLGQGATRLLHSWQSIAPRLADDLWLR 1
R ++K++LVPVPP VT+F++T+TL +GAT L+H WQ +AP+ ++L++R
Sbjct: 227 RGGGGGSFGVVLSWKIKLVPVPPTVTMFTITKTLEEGATGLVHKWQEVAPKFPNELFMR 285
>ref|XP_003546280.1| PREDICTED: inactive tetrahydrocannabinolic acid synthase-like
[Glycine max]
Length = 543
Score = 121 bits (303), Expect = 1e-25
Identities = 57/119 (47%), Positives = 81/119 (68%)
Frame = -2
Query: 357 FPAGICSTVXXXXXXXXXXXXSLQRKYGVSADNIVDAKLVNAEGELLTRETMEEDLFWAI 178
FPAG+C+++ S+ RKYG+ ADN++DA++V+A G++L RE M EDLFWAI
Sbjct: 168 FPAGLCTSLGVGGHITGGAYGSMMRKYGLGADNVLDARIVDANGQILDREAMGEDLFWAI 227
Query: 177 RXXXXXXXXXXXAYKLRLVPVPPKVTVFSVTRTLGQGATRLLHSWQSIAPRLADDLWLR 1
R +K++LVPVP VTVF+VTR+L Q ATR+LH WQ +AP + +DL++R
Sbjct: 228 RGGGGASFGILLWWKIKLVPVPETVTVFTVTRSLEQDATRILHRWQEVAPYIDEDLFIR 286
>ref|XP_003535119.1| PREDICTED: cannabidiolic acid synthase-like 1-like isoform 1
[Glycine max]
Length = 543
Score = 121 bits (303), Expect = 1e-25
Identities = 57/119 (47%), Positives = 81/119 (68%)
Frame = -2
Query: 357 FPAGICSTVXXXXXXXXXXXXSLQRKYGVSADNIVDAKLVNAEGELLTRETMEEDLFWAI 178
FPAG+C+++ S+ RKYG+ ADN+VDA++V+A G++L RE M EDLFWAI
Sbjct: 168 FPAGLCTSLGVGGHITGGAYGSMMRKYGLGADNVVDARIVDANGQILDREAMGEDLFWAI 227
Query: 177 RXXXXXXXXXXXAYKLRLVPVPPKVTVFSVTRTLGQGATRLLHSWQSIAPRLADDLWLR 1
R +K++LVPVP VTVF+VTR+L Q AT++LH WQ +AP + +DL++R
Sbjct: 228 RGGGGASFGILLWWKIKLVPVPETVTVFTVTRSLEQDATKILHRWQEVAPYIDEDLFIR 286
>ref|XP_004134554.1| PREDICTED: reticuline oxidase-like protein-like [Cucumis sativus]
Length = 549
Score = 120 bits (300), Expect = 2e-25
Identities = 58/119 (48%), Positives = 78/119 (65%)
Frame = -2
Query: 357 FPAGICSTVXXXXXXXXXXXXSLQRKYGVSADNIVDAKLVNAEGELLTRETMEEDLFWAI 178
FPAG+C ++ S+ RKYG+ ADN+VDA++V+A G +L RE M EDLFWAI
Sbjct: 175 FPAGLCPSLGVGGHITGGAYGSMMRKYGLGADNVVDARIVDANGRILNREAMGEDLFWAI 234
Query: 177 RXXXXXXXXXXXAYKLRLVPVPPKVTVFSVTRTLGQGATRLLHSWQSIAPRLADDLWLR 1
R +KL LVPVP VTVF+V +TL QGAT++L+ WQ +A +L DDL++R
Sbjct: 235 RGGGGGSFGIILWWKLNLVPVPSTVTVFTVAKTLEQGATKILYKWQQVADKLDDDLFIR 293
>ref|XP_006468345.1| PREDICTED: reticuline oxidase-like protein-like [Citrus sinensis]
Length = 535
Score = 119 bits (299), Expect = 3e-25
Identities = 56/119 (47%), Positives = 83/119 (69%)
Frame = -2
Query: 357 FPAGICSTVXXXXXXXXXXXXSLQRKYGVSADNIVDAKLVNAEGELLTRETMEEDLFWAI 178
FPAG+C+++ S+ RKYG+ ADN++DA++V+A G++L RE M EDLFWAI
Sbjct: 170 FPAGLCTSLGVGGHITGGAYGSMMRKYGLGADNVLDARIVDANGKILDREAMGEDLFWAI 229
Query: 177 RXXXXXXXXXXXAYKLRLVPVPPKVTVFSVTRTLGQGATRLLHSWQSIAPRLADDLWLR 1
R ++K++LVPVP VTVF+VT+TL QGAT++L+ WQ +A +L +DL++R
Sbjct: 230 RGGGGASFGIILSWKIKLVPVPETVTVFTVTKTLEQGATKILYRWQQVADKLDEDLFIR 288
>ref|XP_006448862.1| hypothetical protein CICLE_v10014829mg [Citrus clementina]
gi|557551473|gb|ESR62102.1| hypothetical protein
CICLE_v10014829mg [Citrus clementina]
Length = 542
Score = 119 bits (299), Expect = 3e-25
Identities = 56/119 (47%), Positives = 83/119 (69%)
Frame = -2
Query: 357 FPAGICSTVXXXXXXXXXXXXSLQRKYGVSADNIVDAKLVNAEGELLTRETMEEDLFWAI 178
FPAG+C+++ S+ RKYG+ ADN++DA++V+A G++L RE M EDLFWAI
Sbjct: 177 FPAGLCTSLGVGGHITGGAYGSMMRKYGLGADNVLDARIVDANGKILDREAMGEDLFWAI 236
Query: 177 RXXXXXXXXXXXAYKLRLVPVPPKVTVFSVTRTLGQGATRLLHSWQSIAPRLADDLWLR 1
R ++K++LVPVP VTVF+VT+TL QGAT++L+ WQ +A +L +DL++R
Sbjct: 237 RGGGGASFGIILSWKIKLVPVPETVTVFTVTKTLEQGATKILYRWQQVADKLDEDLFIR 295
>gb|EMJ13559.1| hypothetical protein PRUPE_ppa014683mg [Prunus persica]
Length = 476
Score = 119 bits (299), Expect = 3e-25
Identities = 61/119 (51%), Positives = 79/119 (66%)
Frame = -2
Query: 357 FPAGICSTVXXXXXXXXXXXXSLQRKYGVSADNIVDAKLVNAEGELLTRETMEEDLFWAI 178
FPAG+C TV +L RKYG+S DNIVDAKLV+A G +L R++M ED+FWA+
Sbjct: 116 FPAGVCPTVGAGGHISGGGYGNLMRKYGLSIDNIVDAKLVDANGRILDRKSMGEDIFWAL 175
Query: 177 RXXXXXXXXXXXAYKLRLVPVPPKVTVFSVTRTLGQGATRLLHSWQSIAPRLADDLWLR 1
R ++KL+LV VP KVTVF+VT+TL QG T +L+ WQ +AP L DL+LR
Sbjct: 176 RGGGGASFGVILSWKLKLVRVPEKVTVFNVTKTLEQGVTDVLYKWQFVAPVLPKDLFLR 234
>ref|XP_003531073.1| PREDICTED: tetrahydrocannabinolic acid synthase-like [Glycine max]
Length = 523
Score = 119 bits (299), Expect = 3e-25
Identities = 58/119 (48%), Positives = 80/119 (67%)
Frame = -2
Query: 357 FPAGICSTVXXXXXXXXXXXXSLQRKYGVSADNIVDAKLVNAEGELLTRETMEEDLFWAI 178
FPAG C+++ S+ RKYG+ ADN++DAK+V+A G +L R+ M EDLFWAI
Sbjct: 168 FPAGTCTSLGIGGHITGGAYGSMVRKYGLGADNVLDAKIVDANGRILDRKAMGEDLFWAI 227
Query: 177 RXXXXXXXXXXXAYKLRLVPVPPKVTVFSVTRTLGQGATRLLHSWQSIAPRLADDLWLR 1
R +K++LVPVPP VTVF+V +TL QGAT+LLH WQ +AP L ++L++R
Sbjct: 228 RGGGGGSFGILLWWKVKLVPVPPTVTVFTVKKTLEQGATKLLHRWQEVAPFLDENLFIR 286
>ref|XP_003524780.1| PREDICTED: tetrahydrocannabinolic acid synthase-like [Glycine max]
Length = 531
Score = 119 bits (299), Expect = 3e-25
Identities = 54/119 (45%), Positives = 81/119 (68%)
Frame = -2
Query: 357 FPAGICSTVXXXXXXXXXXXXSLQRKYGVSADNIVDAKLVNAEGELLTRETMEEDLFWAI 178
FPAG+C+++ ++ RKYG+ DN++DA++V+A G +L RE M EDLFWAI
Sbjct: 169 FPAGLCTSLGIGGHITGGAYGTMMRKYGLGVDNVLDAQIVDANGRVLDREAMGEDLFWAI 228
Query: 177 RXXXXXXXXXXXAYKLRLVPVPPKVTVFSVTRTLGQGATRLLHSWQSIAPRLADDLWLR 1
R +K++LVPVPP VTVF+VT++L QGAT++LH WQ +AP + ++L++R
Sbjct: 229 RGGGGGSFGILLWWKIKLVPVPPTVTVFTVTKSLEQGATKILHRWQEVAPYIDENLFIR 287
>ref|XP_003531072.2| PREDICTED: reticuline oxidase-like protein-like [Glycine max]
Length = 593
Score = 119 bits (297), Expect = 5e-25
Identities = 55/119 (46%), Positives = 81/119 (68%)
Frame = -2
Query: 357 FPAGICSTVXXXXXXXXXXXXSLQRKYGVSADNIVDAKLVNAEGELLTRETMEEDLFWAI 178
FPAG+C+T+ S+ RKYG+ ADN++DA++V+A G++L R+ M EDLFWAI
Sbjct: 228 FPAGLCTTLGIGGHITGGAYGSMMRKYGLGADNVLDARIVDANGKVLDRKAMGEDLFWAI 287
Query: 177 RXXXXXXXXXXXAYKLRLVPVPPKVTVFSVTRTLGQGATRLLHSWQSIAPRLADDLWLR 1
R +K++LVPVP VTVF+VT+TL QG ++LLH WQ +AP + ++L++R
Sbjct: 288 RGGGGGSFGVILWWKIKLVPVPQTVTVFTVTKTLEQGGSKLLHRWQQVAPHIDENLFIR 346