BLASTX 2.2.25 [Feb-01-2011]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= Zingiber24_contig00014813
         (2329 letters)

Database: ./nr 
           37,332,560 sequences; 13,225,080,153 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

ref|XP_002272383.2| PREDICTED: niemann-Pick C1 protein-like [Vit...   945   0.0  
ref|XP_006855752.1| hypothetical protein AMTR_s00044p00170650 [A...   932   0.0  
emb|CBI40718.3| unnamed protein product [Vitis vinifera]              932   0.0  
ref|XP_006342140.1| PREDICTED: niemann-Pick C1 protein-like [Sol...   931   0.0  
ref|XP_004238435.1| PREDICTED: niemann-Pick C1 protein-like [Sol...   931   0.0  
ref|XP_006386142.1| patched family protein [Populus trichocarpa]...   930   0.0  
ref|XP_006386141.1| hypothetical protein POPTR_0002s01050g [Popu...   930   0.0  
ref|XP_006386140.1| hypothetical protein POPTR_0002s01050g [Popu...   930   0.0  
gb|EXB56311.1| Niemann-Pick C1 protein [Morus notabilis]              930   0.0  
ref|XP_002307793.2| patched family protein [Populus trichocarpa]...   926   0.0  
ref|XP_006383771.1| hypothetical protein POPTR_0005s27320g [Popu...   926   0.0  
ref|XP_006473797.1| PREDICTED: niemann-Pick C1 protein-like isof...   926   0.0  
ref|XP_006435367.1| hypothetical protein CICLE_v10000039mg [Citr...   925   0.0  
ref|XP_004976504.1| PREDICTED: niemann-Pick C1 protein-like [Set...   921   0.0  
ref|XP_002510680.1| hedgehog receptor, putative [Ricinus communi...   917   0.0  
ref|XP_006486599.1| PREDICTED: niemann-Pick C1 protein-like [Cit...   915   0.0  
ref|XP_006383769.1| hypothetical protein POPTR_0005s27320g [Popu...   914   0.0  
gb|EXC31541.1| Niemann-Pick C1 protein [Morus notabilis]              914   0.0  
gb|EOX97440.1| Hedgehog receptor, putative isoform 4 [Theobroma ...   914   0.0  
gb|EOX97439.1| Hedgehog receptor, putative isoform 3 [Theobroma ...   914   0.0  

>ref|XP_002272383.2| PREDICTED: niemann-Pick C1 protein-like [Vitis vinifera]
          Length = 1309

 Score =  945 bits (2443), Expect = 0.0
 Identities = 467/730 (63%), Positives = 569/730 (77%), Gaps = 6/730 (0%)
 Frame = -1

Query: 2173 AQERYAKGYCSMYGICGQRSDGKALNCPNYTRSIKPDELLSSKIQSLCPTITGNVCCTAE 1994
            A ER+++ YC+MY ICG+RSDGK LNCP  + S+KPD+LLSSKIQS+CPTI+GNVCCT  
Sbjct: 57   ASERHSEEYCAMYDICGKRSDGKVLNCPYGSPSVKPDDLLSSKIQSMCPTISGNVCCTEA 116

Query: 1993 QFETLREQVQQAVPLLVGCPACLRNFLNLFCELSCSPDQSLFINVTSAKQVNGSMTVDSI 1814
            QF+TLR QVQQA+P LVGCPACLRNFLNLFCEL+CSP+QSLFINVTS  +VN ++TVD I
Sbjct: 117  QFDTLRTQVQQAIPFLVGCPACLRNFLNLFCELTCSPNQSLFINVTSVSKVNNNLTVDGI 176

Query: 1813 DFFVTHQFGEQLFNSCKDVKFGTMNTRSMDFVGAGAQNYSEWFTFLGRQANLNEPGSPYP 1634
            +F +T  FGE L+NSCKDVKFGTMNTR++DF+GAGA+ + EWF F+G +A  + PGSPY 
Sbjct: 177  EFIITDAFGEGLYNSCKDVKFGTMNTRAIDFIGAGAKTFKEWFAFIGTRAAPSVPGSPYA 236

Query: 1633 ITFTSYISGLSGIKPMNATTYSCGDSSMGFSCGDCPSSAVCIDSLSPAPHVKQSCSIKLI 1454
            I F   I+  SG+KPMN +TYSCGD+S+G SCGDCPS++VC     P+ H + SCS+++ 
Sbjct: 237  INFQPSIAESSGMKPMNVSTYSCGDNSLGCSCGDCPSASVCSGYAPPSLHKEGSCSVRIG 296

Query: 1453 SLKVKCLDFSLVIIYLFIVCAFLVWNFVYIKKKEGPF-RTKPLLNVKGES-----SNDKQ 1292
            SLK KC++FSL I+Y+ +V  F  W   +  ++  P  R KP+LNV   S     +  K 
Sbjct: 297  SLKAKCIEFSLAILYIILVTIFFGWGLFHRTRERNPAPRMKPMLNVMDGSELHSMNRPKD 356

Query: 1291 ETHVSQTTAMVPSGLKAHDPSVIQLYMSNFFRKYGTFVSKNPTXXXXXXXXXXXXXXXXX 1112
            E   SQ    VP        S++Q YMSNF+R+YGT+V+++PT                 
Sbjct: 357  ENLSSQMLEDVPQIRNGVQLSIVQGYMSNFYRRYGTWVARHPTIMLCSSLAIVLVLCLGL 416

Query: 1111 IHFKVETRPEKLWVGPGSRAAKEKQYFDSHLAPFYRIEQILLASVSPSVGERPPSIVTEQ 932
            I FKVETRPEKLWVGPGS+AA+EKQ+FDSHLAPFYRIEQ++LA++ P      PSIVTE 
Sbjct: 417  IRFKVETRPEKLWVGPGSKAAEEKQFFDSHLAPFYRIEQLVLATI-PDANGISPSIVTEN 475

Query: 931  NLKLLFEIQKKVDNLHANYSGSMVSLSDICLKPLGNDCATQSVLQYFQMDLQNYDTYGGL 752
            N+KLLFEIQKKVD L AN+SGSM+SL+DIC+KPLG DCATQSVLQYF+MD +NYD YGG+
Sbjct: 476  NIKLLFEIQKKVDGLRANFSGSMISLTDICMKPLGQDCATQSVLQYFKMDSRNYDDYGGV 535

Query: 751  THAEYCFEHFSSDQTCLSAFTAPLDPSTALGGFSGNNYSEASAFVITYPVNNVLDETSIE 572
             H EYCF+H++S  TC+SAF APLDPSTALGGFSGNNYSEASAF++TYPVNN +D+   E
Sbjct: 536  QHVEYCFQHYTSADTCMSAFKAPLDPSTALGGFSGNNYSEASAFIVTYPVNNAIDKEGNE 595

Query: 571  FRNAVAWEKAFIQLIKDEIVPMVQAQNLTLAFSSESSIQEELKRESTADVITILVSYLVM 392
               AVAWEKAFIQ++KD+++PM+Q++NLTL+FSSESSI+EELKRESTAD ITI +SYLVM
Sbjct: 596  TGKAVAWEKAFIQIVKDDLLPMMQSKNLTLSFSSESSIEEELKRESTADAITISISYLVM 655

Query: 391  FAYISITLGEKHQLSSIFXXXXXXXXXXXXXXXXXXXXXSIGFYSSIGVKSTLIIMEVIP 212
            FAYIS+TLG+  +LSS +                     S+GF+S+IGVKSTLIIMEVIP
Sbjct: 656  FAYISLTLGDTPRLSSFYISSKIFLGLAGVMLVMLSVLGSVGFFSAIGVKSTLIIMEVIP 715

Query: 211  FLVLAVGVDNMCILVHAINRQPLELLLEERISNALTEVGPSITLASLSEVLAFAVGSFIP 32
            FLVLAVGVDNMCILVHA+ RQPLEL LE RISNAL EVGPSITLASL+EVLAFAVG+FIP
Sbjct: 716  FLVLAVGVDNMCILVHAVKRQPLELPLEGRISNALVEVGPSITLASLAEVLAFAVGTFIP 775

Query: 31   MPACRVFSMF 2
            MPACRVFSMF
Sbjct: 776  MPACRVFSMF 785


>ref|XP_006855752.1| hypothetical protein AMTR_s00044p00170650 [Amborella trichopoda]
            gi|548859539|gb|ERN17219.1| hypothetical protein
            AMTR_s00044p00170650 [Amborella trichopoda]
          Length = 1297

 Score =  932 bits (2410), Expect = 0.0
 Identities = 465/729 (63%), Positives = 570/729 (78%), Gaps = 9/729 (1%)
 Frame = -1

Query: 2161 YAKGYCSMYGICGQRSDGKALNCPNYTRSIKPDELLSSKIQSLCPTITGNVCCTAEQFET 1982
            +AK YC+MYGICGQR DGK LNCP  + ++KPDEL SSKIQSLC TITGNVCCT +QFET
Sbjct: 50   HAKDYCAMYGICGQRKDGKVLNCPYGSPAVKPDELFSSKIQSLCSTITGNVCCTEDQFET 109

Query: 1981 LREQVQQAVPLLVGCPACLRNFLNLFCELSCSPDQSLFINVTSAKQVNGSMTVDSIDFFV 1802
            LR QVQQAVP LVGCPACLRNFLNLFCELSCSP+QSLFINVTS  +VN ++TVD IDF+V
Sbjct: 110  LRGQVQQAVPFLVGCPACLRNFLNLFCELSCSPNQSLFINVTSISKVNNTLTVDGIDFYV 169

Query: 1801 THQFGEQLFNSCKDVKFGTMNTRSMDFVGAGAQNYSEWFTFLGRQANLNEPGSPYPITFT 1622
            T  +GE+L+NSCKDVKFGTMNTR+MDF+GAGA++Y +WF F+G +A ++ PGSPY I F 
Sbjct: 170  TGSYGEELYNSCKDVKFGTMNTRAMDFIGAGAKSYKDWFAFIGHRAEMDVPGSPYAINFQ 229

Query: 1621 SYISGLSGIKPMNATTYSCGDSSMGFSCGDCPSSAVCIDSLSPAPHVKQSCSIKLISLKV 1442
            S IS   G++PMN + YSCGD+S+G SCGDCPSS  C  S  P+P  + SCSI   S KV
Sbjct: 230  SKISESFGMEPMNTSVYSCGDTSLGCSCGDCPSSPSCSGSAPPSPPKRHSCSITFPSFKV 289

Query: 1441 KCLDFSLVIIYLFIVCAFLVWNFV---YIKKKEGPFRTKPLLNVKGES---SNDKQETHV 1280
            +C+DF+L IIY+ ++  F  W  +    ++    P R +PLLN + E+   S DKQE  +
Sbjct: 290  RCVDFTLTIIYIVLISTFFGWGILRRTRVRSSHSP-RMRPLLNAEDENQLRSADKQEKEI 348

Query: 1279 --SQTTAMVPSGLKAHDPSVIQLYMSNFFRKYGTFVSKNPTXXXXXXXXXXXXXXXXXIH 1106
              +Q +   P  LK     +IQ Y+S+F+R+YGT+V++NPT                 I 
Sbjct: 349  RPAQMSDDGPQMLKELHLPLIQQYISSFYRRYGTWVARNPTLVLCSSVAIALLLSIGLIR 408

Query: 1105 FKVETRPEKLWVGPGSRAAKEKQYFDSHLAPFYRIEQILLASVSPSVGE-RPPSIVTEQN 929
            FKVE+RPEKLWVGPGS+AA+EKQ+FDSHLAPFYRIEQ++LA+V P +G+   PSIVTE+N
Sbjct: 409  FKVESRPEKLWVGPGSKAAEEKQFFDSHLAPFYRIEQLILATV-PDLGQGNTPSIVTEEN 467

Query: 928  LKLLFEIQKKVDNLHANYSGSMVSLSDICLKPLGNDCATQSVLQYFQMDLQNYDTYGGLT 749
            ++LLFEIQKKVD + ANYSGS++SL+DIC+KPLG DCATQSVLQYF+MD  NY++YGG+ 
Sbjct: 468  IQLLFEIQKKVDGIRANYSGSLISLTDICMKPLGADCATQSVLQYFKMDPDNYESYGGVQ 527

Query: 748  HAEYCFEHFSSDQTCLSAFTAPLDPSTALGGFSGNNYSEASAFVITYPVNNVLDETSIEF 569
            H EYCF+H++S +TCLSAF AP+DPS ALGGFSG+N+S+A+AFVITYPV N +DET  E 
Sbjct: 528  HVEYCFQHYTSAETCLSAFQAPVDPSVALGGFSGSNFSQATAFVITYPVRNAVDETGKEN 587

Query: 568  RNAVAWEKAFIQLIKDEIVPMVQAQNLTLAFSSESSIQEELKRESTADVITILVSYLVMF 389
              AVAWEKAFI + K+E+ PM Q++NLTL+FSSESSIQ+EL+RESTADV+TIL+SYLVMF
Sbjct: 588  WEAVAWEKAFINVAKEELRPMAQSRNLTLSFSSESSIQKELERESTADVLTILISYLVMF 647

Query: 388  AYISITLGEKHQLSSIFXXXXXXXXXXXXXXXXXXXXXSIGFYSSIGVKSTLIIMEVIPF 209
            AYIS+TLG+    SS +                     S+GF+S+IGVKSTLIIMEVIPF
Sbjct: 648  AYISVTLGDAPHFSSFYISSKVLLGLSGVVLVMLSVLGSVGFFSAIGVKSTLIIMEVIPF 707

Query: 208  LVLAVGVDNMCILVHAINRQPLELLLEERISNALTEVGPSITLASLSEVLAFAVGSFIPM 29
            LVLAVGVDNMCILVHA+ RQ +EL L+ER+SNAL EVGPSITLASLSEV+AFAVGSFIPM
Sbjct: 708  LVLAVGVDNMCILVHAVKRQSMELPLDERVSNALVEVGPSITLASLSEVVAFAVGSFIPM 767

Query: 28   PACRVFSMF 2
            PACRVFSMF
Sbjct: 768  PACRVFSMF 776


>emb|CBI40718.3| unnamed protein product [Vitis vinifera]
          Length = 1242

 Score =  932 bits (2410), Expect = 0.0
 Identities = 462/719 (64%), Positives = 560/719 (77%), Gaps = 6/719 (0%)
 Frame = -1

Query: 2140 MYGICGQRSDGKALNCPNYTRSIKPDELLSSKIQSLCPTITGNVCCTAEQFETLREQVQQ 1961
            MY ICG+RSDGK LNCP  + S+KPD+LLSSKIQS+CPTI+GNVCCT  QF+TLR QVQQ
Sbjct: 1    MYDICGKRSDGKVLNCPYGSPSVKPDDLLSSKIQSMCPTISGNVCCTEAQFDTLRTQVQQ 60

Query: 1960 AVPLLVGCPACLRNFLNLFCELSCSPDQSLFINVTSAKQVNGSMTVDSIDFFVTHQFGEQ 1781
            A+P LVGCPACLRNFLNLFCEL+CSP+QSLFINVTS  +VN ++TVD I+F +T  FGE 
Sbjct: 61   AIPFLVGCPACLRNFLNLFCELTCSPNQSLFINVTSVSKVNNNLTVDGIEFIITDAFGEG 120

Query: 1780 LFNSCKDVKFGTMNTRSMDFVGAGAQNYSEWFTFLGRQANLNEPGSPYPITFTSYISGLS 1601
            L+NSCKDVKFGTMNTR++DF+GAGA+ + EWF F+G +A  + PGSPY I F   I+  S
Sbjct: 121  LYNSCKDVKFGTMNTRAIDFIGAGAKTFKEWFAFIGTRAAPSVPGSPYAINFQPSIAESS 180

Query: 1600 GIKPMNATTYSCGDSSMGFSCGDCPSSAVCIDSLSPAPHVKQSCSIKLISLKVKCLDFSL 1421
            G+KPMN +TYSCGD+S+G SCGDCPS++VC     P+ H + SCS+++ SLK KC++FSL
Sbjct: 181  GMKPMNVSTYSCGDNSLGCSCGDCPSASVCSGYAPPSLHKEGSCSVRIGSLKAKCIEFSL 240

Query: 1420 VIIYLFIVCAFLVWNFVYIKKKEGPF-RTKPLLNVKGES-----SNDKQETHVSQTTAMV 1259
             I+Y+ +V  F  W   +  ++  P  R KP+LNV   S     +  K E   SQ    V
Sbjct: 241  AILYIILVTIFFGWGLFHRTRERNPAPRMKPMLNVMDGSELHSMNRPKDENLSSQMLEDV 300

Query: 1258 PSGLKAHDPSVIQLYMSNFFRKYGTFVSKNPTXXXXXXXXXXXXXXXXXIHFKVETRPEK 1079
            P        S++Q YMSNF+R+YGT+V+++PT                 I FKVETRPEK
Sbjct: 301  PQIRNGVQLSIVQGYMSNFYRRYGTWVARHPTIMLCSSLAIVLVLCLGLIRFKVETRPEK 360

Query: 1078 LWVGPGSRAAKEKQYFDSHLAPFYRIEQILLASVSPSVGERPPSIVTEQNLKLLFEIQKK 899
            LWVGPGS+AA+EKQ+FDSHLAPFYRIEQ++LA++ P      PSIVTE N+KLLFEIQKK
Sbjct: 361  LWVGPGSKAAEEKQFFDSHLAPFYRIEQLVLATI-PDANGISPSIVTENNIKLLFEIQKK 419

Query: 898  VDNLHANYSGSMVSLSDICLKPLGNDCATQSVLQYFQMDLQNYDTYGGLTHAEYCFEHFS 719
            VD L AN+SGSM+SL+DIC+KPLG DCATQSVLQYF+MD +NYD YGG+ H EYCF+H++
Sbjct: 420  VDGLRANFSGSMISLTDICMKPLGQDCATQSVLQYFKMDSRNYDDYGGVQHVEYCFQHYT 479

Query: 718  SDQTCLSAFTAPLDPSTALGGFSGNNYSEASAFVITYPVNNVLDETSIEFRNAVAWEKAF 539
            S  TC+SAF APLDPSTALGGFSGNNYSEASAF++TYPVNN +D+   E   AVAWEKAF
Sbjct: 480  SADTCMSAFKAPLDPSTALGGFSGNNYSEASAFIVTYPVNNAIDKEGNETGKAVAWEKAF 539

Query: 538  IQLIKDEIVPMVQAQNLTLAFSSESSIQEELKRESTADVITILVSYLVMFAYISITLGEK 359
            IQ++KD+++PM+Q++NLTL+FSSESSI+EELKRESTAD ITI +SYLVMFAYIS+TLG+ 
Sbjct: 540  IQIVKDDLLPMMQSKNLTLSFSSESSIEEELKRESTADAITISISYLVMFAYISLTLGDT 599

Query: 358  HQLSSIFXXXXXXXXXXXXXXXXXXXXXSIGFYSSIGVKSTLIIMEVIPFLVLAVGVDNM 179
             +LSS +                     S+GF+S+IGVKSTLIIMEVIPFLVLAVGVDNM
Sbjct: 600  PRLSSFYISSKIFLGLAGVMLVMLSVLGSVGFFSAIGVKSTLIIMEVIPFLVLAVGVDNM 659

Query: 178  CILVHAINRQPLELLLEERISNALTEVGPSITLASLSEVLAFAVGSFIPMPACRVFSMF 2
            CILVHA+ RQPLEL LE RISNAL EVGPSITLASL+EVLAFAVG+FIPMPACRVFSMF
Sbjct: 660  CILVHAVKRQPLELPLEGRISNALVEVGPSITLASLAEVLAFAVGTFIPMPACRVFSMF 718


>ref|XP_006342140.1| PREDICTED: niemann-Pick C1 protein-like [Solanum tuberosum]
          Length = 1300

 Score =  931 bits (2407), Expect = 0.0
 Identities = 459/728 (63%), Positives = 559/728 (76%), Gaps = 6/728 (0%)
 Frame = -1

Query: 2167 ERYAKGYCSMYGICGQRSDGKALNCPNYTRSIKPDELLSSKIQSLCPTITGNVCCTAEQF 1988
            ER+A+GYC+MY ICG RSDGK LNCP  + S+KP ELLSSKIQSLCPTITGNVCCT  QF
Sbjct: 49   ERHAEGYCAMYDICGARSDGKVLNCPFGSPSVKPGELLSSKIQSLCPTITGNVCCTETQF 108

Query: 1987 ETLREQVQQAVPLLVGCPACLRNFLNLFCELSCSPDQSLFINVTSAKQVNGSMTVDSIDF 1808
            +TLR QVQQA+P LVGCPACLRNFLNLFCEL+CSP+QS FINVTS  +V  + TVD IDF
Sbjct: 109  DTLRSQVQQAIPFLVGCPACLRNFLNLFCELTCSPNQSQFINVTSISKVKKNSTVDGIDF 168

Query: 1807 FVTHQFGEQLFNSCKDVKFGTMNTRSMDFVGAGAQNYSEWFTFLGRQANLNEPGSPYPIT 1628
            F+T  FGE L+ SCKDVKFGTMNTR+++F+GAGA+N+ EW+ F+GR A    PGSPY I 
Sbjct: 169  FITDAFGEGLYESCKDVKFGTMNTRAIEFIGAGAKNFREWYAFIGRLAPPGVPGSPYAIN 228

Query: 1627 FTSYISGLSGIKPMNATTYSCGDSSMGFSCGDCPSSAVCIDSLSPAPHVKQSCSIKLISL 1448
            F++     SG+KPMN +TYSC D+S+G SCGDCPS++VC  S  P    + SCS++  SL
Sbjct: 229  FSATAPESSGMKPMNVSTYSCSDTSLGCSCGDCPSASVCSSSAPPPAQTEGSCSVRFGSL 288

Query: 1447 KVKCLDFSLVIIYLFIVCAFLVWNFVYIKKKEGPF-RTKPLLNVKG-----ESSNDKQET 1286
            KVKC++ ++ I+Y+ +V  FL W F++ K++E P  RTKPL++  G     +SS  K E 
Sbjct: 289  KVKCIEVAVTILYVVLVSIFLGWGFLHKKREETPVPRTKPLISASGNGVIRQSSRQKDEN 348

Query: 1285 HVSQTTAMVPSGLKAHDPSVIQLYMSNFFRKYGTFVSKNPTXXXXXXXXXXXXXXXXXIH 1106
               Q    VP        S++Q YMS F+R+YGT+V++NP                    
Sbjct: 349  IPMQMLEDVPQISSGVQLSIVQGYMSKFYRRYGTWVARNPILVLCSSLFIVLVLCLGLFR 408

Query: 1105 FKVETRPEKLWVGPGSRAAKEKQYFDSHLAPFYRIEQILLASVSPSVGERPPSIVTEQNL 926
            FKVETRPEKLWVG GSRAA+EK +FDSHLAPFYRIEQ+++ ++S +   + P IVTE N+
Sbjct: 409  FKVETRPEKLWVGHGSRAAEEKLFFDSHLAPFYRIEQLIIGTISDADNGKSPPIVTEDNM 468

Query: 925  KLLFEIQKKVDNLHANYSGSMVSLSDICLKPLGNDCATQSVLQYFQMDLQNYDTYGGLTH 746
            KLLF+IQKK+D + ANYSGSMVSL DIC+KPLG +CATQS+LQYF+MD  N+D  GG+ H
Sbjct: 469  KLLFDIQKKIDAIQANYSGSMVSLPDICMKPLGTECATQSILQYFKMDRSNFDNLGGIEH 528

Query: 745  AEYCFEHFSSDQTCLSAFTAPLDPSTALGGFSGNNYSEASAFVITYPVNNVLDETSIEFR 566
             EYC +H++S ++CLSAF APLDPSTALGGFSGNNYSEASAF++TYPVNN +D+     +
Sbjct: 529  VEYCLQHYTSAESCLSAFKAPLDPSTALGGFSGNNYSEASAFIVTYPVNNAIDKEGNYSK 588

Query: 565  NAVAWEKAFIQLIKDEIVPMVQAQNLTLAFSSESSIQEELKRESTADVITILVSYLVMFA 386
             AVAWEKAFIQL+KDEI+PMV+A+NLTLAFSSESS++EELKRESTAD ITIL+SYLVMFA
Sbjct: 589  KAVAWEKAFIQLVKDEILPMVEAKNLTLAFSSESSVEEELKRESTADAITILISYLVMFA 648

Query: 385  YISITLGEKHQLSSIFXXXXXXXXXXXXXXXXXXXXXSIGFYSSIGVKSTLIIMEVIPFL 206
            YIS+TLGE  + SS +                     S+GF+S++GVKSTLIIMEVIPFL
Sbjct: 649  YISLTLGETPRFSSCYISSKVLLGLSGVILVMLSVLGSVGFFSAVGVKSTLIIMEVIPFL 708

Query: 205  VLAVGVDNMCILVHAINRQPLELLLEERISNALTEVGPSITLASLSEVLAFAVGSFIPMP 26
            VLAVGVDNMCILV+A+ RQP+EL LE R+SNAL EVGPSITLASLSEVLAFAVGSFIPMP
Sbjct: 709  VLAVGVDNMCILVNAVKRQPMELPLEGRVSNALVEVGPSITLASLSEVLAFAVGSFIPMP 768

Query: 25   ACRVFSMF 2
            ACRVFSMF
Sbjct: 769  ACRVFSMF 776


>ref|XP_004238435.1| PREDICTED: niemann-Pick C1 protein-like [Solanum lycopersicum]
          Length = 1294

 Score =  931 bits (2407), Expect = 0.0
 Identities = 459/728 (63%), Positives = 559/728 (76%), Gaps = 6/728 (0%)
 Frame = -1

Query: 2167 ERYAKGYCSMYGICGQRSDGKALNCPNYTRSIKPDELLSSKIQSLCPTITGNVCCTAEQF 1988
            ER+A+GYCSMY ICG RSDGK LNCP  + S+KP ELLSSKIQSLCPTITGNVCCT  QF
Sbjct: 43   ERHAEGYCSMYDICGARSDGKVLNCPFGSPSVKPGELLSSKIQSLCPTITGNVCCTETQF 102

Query: 1987 ETLREQVQQAVPLLVGCPACLRNFLNLFCELSCSPDQSLFINVTSAKQVNGSMTVDSIDF 1808
            +TLR QVQQA+P LVGCPACLRNFLNLFCEL+CSP+QS FINVTS  +V  + TV+ IDF
Sbjct: 103  DTLRSQVQQAIPFLVGCPACLRNFLNLFCELTCSPNQSQFINVTSISKVKKNSTVNGIDF 162

Query: 1807 FVTHQFGEQLFNSCKDVKFGTMNTRSMDFVGAGAQNYSEWFTFLGRQANLNEPGSPYPIT 1628
            F+T  FGE LF SCKDVKFGTMNTR+++F+GAGA+N+ EW+ F+GR A    PGSPY I 
Sbjct: 163  FITDTFGEGLFESCKDVKFGTMNTRAIEFIGAGAKNFREWYAFIGRLAPPGVPGSPYAIN 222

Query: 1627 FTSYISGLSGIKPMNATTYSCGDSSMGFSCGDCPSSAVCIDSLSPAPHVKQSCSIKLISL 1448
            F S     SG+KPMN +TYSC D+S+G SCGDCPS++VC  S  P    + SCS++  SL
Sbjct: 223  FNSTAPESSGMKPMNVSTYSCSDTSLGCSCGDCPSASVCSSSAPPPAQTEGSCSVRFGSL 282

Query: 1447 KVKCLDFSLVIIYLFIVCAFLVWNFVYIKKKEGPF-RTKPLLNVKG-----ESSNDKQET 1286
            KVKC++ ++ I+Y+ +V  FL W F++ K++E P  RTKPL++  G     +SS  K E 
Sbjct: 283  KVKCIEVAVTILYVVLVSVFLGWGFLHKKREETPVSRTKPLISATGNGVIRQSSRQKDEN 342

Query: 1285 HVSQTTAMVPSGLKAHDPSVIQLYMSNFFRKYGTFVSKNPTXXXXXXXXXXXXXXXXXIH 1106
               Q    VP        S++Q YMS F+R+YGT+V++NP                    
Sbjct: 343  IPMQMLEDVPQISSGVQLSIVQGYMSKFYRRYGTWVARNPILVLCSSLFIVLVLCLGLFR 402

Query: 1105 FKVETRPEKLWVGPGSRAAKEKQYFDSHLAPFYRIEQILLASVSPSVGERPPSIVTEQNL 926
            FKVETRPEKLWVG GSRAA+EK +FDSHLAPFYRIEQ+++ ++S +   + P IVTE N+
Sbjct: 403  FKVETRPEKLWVGHGSRAAEEKLFFDSHLAPFYRIEQLIIGTISDADNGKAPPIVTEDNM 462

Query: 925  KLLFEIQKKVDNLHANYSGSMVSLSDICLKPLGNDCATQSVLQYFQMDLQNYDTYGGLTH 746
            KLLF+IQKK+D + ANYSG+MVSL DIC+KPLG +CATQS+LQYF+MD  N+D  GG+ H
Sbjct: 463  KLLFDIQKKIDAIQANYSGAMVSLPDICMKPLGTECATQSILQYFKMDRSNFDNLGGIEH 522

Query: 745  AEYCFEHFSSDQTCLSAFTAPLDPSTALGGFSGNNYSEASAFVITYPVNNVLDETSIEFR 566
             EYCF+H++S ++CLSAF APLDP+TALGGFSGNNYSEASAF++TYPVNN +D+     +
Sbjct: 523  VEYCFQHYTSAESCLSAFKAPLDPNTALGGFSGNNYSEASAFIVTYPVNNAIDKEGNYSK 582

Query: 565  NAVAWEKAFIQLIKDEIVPMVQAQNLTLAFSSESSIQEELKRESTADVITILVSYLVMFA 386
             AVAWEKAFIQL+KDEI+PMV+A+NLTLAFSSESS++EELKRESTAD ITIL+SYLVMFA
Sbjct: 583  KAVAWEKAFIQLVKDEILPMVEAKNLTLAFSSESSVEEELKRESTADAITILISYLVMFA 642

Query: 385  YISITLGEKHQLSSIFXXXXXXXXXXXXXXXXXXXXXSIGFYSSIGVKSTLIIMEVIPFL 206
            YIS+TLG+  + SS +                     S+GF+S++GVKSTLIIMEVIPFL
Sbjct: 643  YISLTLGDTPRFSSCYISSKVLLGLSGVILVMLSVLGSVGFFSAVGVKSTLIIMEVIPFL 702

Query: 205  VLAVGVDNMCILVHAINRQPLELLLEERISNALTEVGPSITLASLSEVLAFAVGSFIPMP 26
            VLAVGVDNMCILV+A+ RQP+EL LE R+SNAL EVGPSITLASLSEVLAFAVGSFIPMP
Sbjct: 703  VLAVGVDNMCILVNAVKRQPMELPLEGRVSNALVEVGPSITLASLSEVLAFAVGSFIPMP 762

Query: 25   ACRVFSMF 2
            ACRVFSMF
Sbjct: 763  ACRVFSMF 770


>ref|XP_006386142.1| patched family protein [Populus trichocarpa]
            gi|550344030|gb|ERP63939.1| patched family protein
            [Populus trichocarpa]
          Length = 1294

 Score =  930 bits (2404), Expect = 0.0
 Identities = 463/725 (63%), Positives = 556/725 (76%), Gaps = 3/725 (0%)
 Frame = -1

Query: 2167 ERYAKGYCSMYGICGQRSDGKALNCPNYTRSIKPDELLSSKIQSLCPTITGNVCCTAEQF 1988
            ER+++ YC+MY ICG R DGK +NCP  + S+KPD+LLS KIQSLCPTITGNVCC+  QF
Sbjct: 46   ERHSEEYCAMYDICGAREDGKVVNCPFGSPSVKPDDLLSQKIQSLCPTITGNVCCSEAQF 105

Query: 1987 ETLREQVQQAVPLLVGCPACLRNFLNLFCELSCSPDQSLFINVTSAKQVNGSMTVDSIDF 1808
            ETLR QVQQA+P LVGCPACLRNFLNLFCEL+CSP QS+FINVTS  +V G++TV  IDF
Sbjct: 106  ETLRSQVQQAIPFLVGCPACLRNFLNLFCELTCSPHQSMFINVTSTDKVEGNLTVSGIDF 165

Query: 1807 FVTHQFGEQLFNSCKDVKFGTMNTRSMDFVGAGAQNYSEWFTFLGRQANLNEPGSPYPIT 1628
            +V   FGE L+ SCKDVKFGTMN+R+++F+GAGA+N++EW+ F+GR+A LN PGSPY +T
Sbjct: 166  YVYDSFGEGLYESCKDVKFGTMNSRALNFIGAGAKNFTEWYAFIGRRAPLNVPGSPYAMT 225

Query: 1627 FTSYISGLSGIKPMNATTYSCGDSSMGFSCGDCPSSAVCIDSLSPAPHVKQSCSIKLISL 1448
            F       SG+KPMN +TYSCGD S+G SCGDCP S VC ++  P  H   SC++++ SL
Sbjct: 226  FKPSAPESSGMKPMNVSTYSCGDISLGCSCGDCPQSPVCANTDPPPHHEGASCAVRIGSL 285

Query: 1447 KVKCLDFSLVIIYLFIVCAFLVWNFVYIKK-KEGPFRTKPLLNVK--GESSNDKQETHVS 1277
            K KC+DF L I+Y+ +V  FL W   + K+ ++   R  P+ N+K  GE +  K E    
Sbjct: 286  KAKCVDFILTILYVILVSIFLGWGLFHRKRERDQSSRMNPVSNIKDSGEVTGKKDENLPM 345

Query: 1276 QTTAMVPSGLKAHDPSVIQLYMSNFFRKYGTFVSKNPTXXXXXXXXXXXXXXXXXIHFKV 1097
            Q     P        S++Q YMS F+R YGT+V++NP                  I FKV
Sbjct: 346  QMLEDSPQTGSRVQLSIVQGYMSKFYRCYGTWVARNPILVLSLSLAVILLLCLGLIRFKV 405

Query: 1096 ETRPEKLWVGPGSRAAKEKQYFDSHLAPFYRIEQILLASVSPSVGERPPSIVTEQNLKLL 917
            ETRPEKLWVGPGS+ A+EK++FD+HLAPFYRIEQ++LA+V  +  ++ PSIVTE N+KLL
Sbjct: 406  ETRPEKLWVGPGSKVAEEKRFFDTHLAPFYRIEQLILATVPEAGAQKRPSIVTENNIKLL 465

Query: 916  FEIQKKVDNLHANYSGSMVSLSDICLKPLGNDCATQSVLQYFQMDLQNYDTYGGLTHAEY 737
            FEIQKKVD +HANYSG+MVSL DICLKPL  DCATQSVLQYFQMD QN D YGG+ H  Y
Sbjct: 466  FEIQKKVDGIHANYSGTMVSLPDICLKPLDKDCATQSVLQYFQMDPQNLDNYGGVEHVNY 525

Query: 736  CFEHFSSDQTCLSAFTAPLDPSTALGGFSGNNYSEASAFVITYPVNNVLDETSIEFRNAV 557
            C +H+SS  TC SAF APLDPSTALGGFSGNNYSEASAF++TYPVNNV+D+   E   AV
Sbjct: 526  CLQHYSSADTCRSAFKAPLDPSTALGGFSGNNYSEASAFIVTYPVNNVIDKEGNETDKAV 585

Query: 556  AWEKAFIQLIKDEIVPMVQAQNLTLAFSSESSIQEELKRESTADVITILVSYLVMFAYIS 377
            AWEKAFIQL+K+E++PMVQ++NLTL+FSSESSI+EELKRESTADVITIL+SYLVMFAYIS
Sbjct: 586  AWEKAFIQLVKNELLPMVQSKNLTLSFSSESSIEEELKRESTADVITILISYLVMFAYIS 645

Query: 376  ITLGEKHQLSSIFXXXXXXXXXXXXXXXXXXXXXSIGFYSSIGVKSTLIIMEVIPFLVLA 197
            +TLG+   LSS +                     S+GF+S+IGVKSTLIIMEVIPFLVLA
Sbjct: 646  LTLGDTPHLSSFYISSKVLLGLSGVLLVMLSVLGSVGFFSAIGVKSTLIIMEVIPFLVLA 705

Query: 196  VGVDNMCILVHAINRQPLELLLEERISNALTEVGPSITLASLSEVLAFAVGSFIPMPACR 17
            VGVDNMCILVHA+ RQP+EL LE RISNAL EVGPSITLASLSEVLAFAVGSFIPMPACR
Sbjct: 706  VGVDNMCILVHAVKRQPMELPLEGRISNALVEVGPSITLASLSEVLAFAVGSFIPMPACR 765

Query: 16   VFSMF 2
            VFSMF
Sbjct: 766  VFSMF 770


>ref|XP_006386141.1| hypothetical protein POPTR_0002s01050g [Populus trichocarpa]
            gi|550344029|gb|ERP63938.1| hypothetical protein
            POPTR_0002s01050g [Populus trichocarpa]
          Length = 1131

 Score =  930 bits (2404), Expect = 0.0
 Identities = 463/725 (63%), Positives = 556/725 (76%), Gaps = 3/725 (0%)
 Frame = -1

Query: 2167 ERYAKGYCSMYGICGQRSDGKALNCPNYTRSIKPDELLSSKIQSLCPTITGNVCCTAEQF 1988
            ER+++ YC+MY ICG R DGK +NCP  + S+KPD+LLS KIQSLCPTITGNVCC+  QF
Sbjct: 46   ERHSEEYCAMYDICGAREDGKVVNCPFGSPSVKPDDLLSQKIQSLCPTITGNVCCSEAQF 105

Query: 1987 ETLREQVQQAVPLLVGCPACLRNFLNLFCELSCSPDQSLFINVTSAKQVNGSMTVDSIDF 1808
            ETLR QVQQA+P LVGCPACLRNFLNLFCEL+CSP QS+FINVTS  +V G++TV  IDF
Sbjct: 106  ETLRSQVQQAIPFLVGCPACLRNFLNLFCELTCSPHQSMFINVTSTDKVEGNLTVSGIDF 165

Query: 1807 FVTHQFGEQLFNSCKDVKFGTMNTRSMDFVGAGAQNYSEWFTFLGRQANLNEPGSPYPIT 1628
            +V   FGE L+ SCKDVKFGTMN+R+++F+GAGA+N++EW+ F+GR+A LN PGSPY +T
Sbjct: 166  YVYDSFGEGLYESCKDVKFGTMNSRALNFIGAGAKNFTEWYAFIGRRAPLNVPGSPYAMT 225

Query: 1627 FTSYISGLSGIKPMNATTYSCGDSSMGFSCGDCPSSAVCIDSLSPAPHVKQSCSIKLISL 1448
            F       SG+KPMN +TYSCGD S+G SCGDCP S VC ++  P  H   SC++++ SL
Sbjct: 226  FKPSAPESSGMKPMNVSTYSCGDISLGCSCGDCPQSPVCANTDPPPHHEGASCAVRIGSL 285

Query: 1447 KVKCLDFSLVIIYLFIVCAFLVWNFVYIKK-KEGPFRTKPLLNVK--GESSNDKQETHVS 1277
            K KC+DF L I+Y+ +V  FL W   + K+ ++   R  P+ N+K  GE +  K E    
Sbjct: 286  KAKCVDFILTILYVILVSIFLGWGLFHRKRERDQSSRMNPVSNIKDSGEVTGKKDENLPM 345

Query: 1276 QTTAMVPSGLKAHDPSVIQLYMSNFFRKYGTFVSKNPTXXXXXXXXXXXXXXXXXIHFKV 1097
            Q     P        S++Q YMS F+R YGT+V++NP                  I FKV
Sbjct: 346  QMLEDSPQTGSRVQLSIVQGYMSKFYRCYGTWVARNPILVLSLSLAVILLLCLGLIRFKV 405

Query: 1096 ETRPEKLWVGPGSRAAKEKQYFDSHLAPFYRIEQILLASVSPSVGERPPSIVTEQNLKLL 917
            ETRPEKLWVGPGS+ A+EK++FD+HLAPFYRIEQ++LA+V  +  ++ PSIVTE N+KLL
Sbjct: 406  ETRPEKLWVGPGSKVAEEKRFFDTHLAPFYRIEQLILATVPEAGAQKRPSIVTENNIKLL 465

Query: 916  FEIQKKVDNLHANYSGSMVSLSDICLKPLGNDCATQSVLQYFQMDLQNYDTYGGLTHAEY 737
            FEIQKKVD +HANYSG+MVSL DICLKPL  DCATQSVLQYFQMD QN D YGG+ H  Y
Sbjct: 466  FEIQKKVDGIHANYSGTMVSLPDICLKPLDKDCATQSVLQYFQMDPQNLDNYGGVEHVNY 525

Query: 736  CFEHFSSDQTCLSAFTAPLDPSTALGGFSGNNYSEASAFVITYPVNNVLDETSIEFRNAV 557
            C +H+SS  TC SAF APLDPSTALGGFSGNNYSEASAF++TYPVNNV+D+   E   AV
Sbjct: 526  CLQHYSSADTCRSAFKAPLDPSTALGGFSGNNYSEASAFIVTYPVNNVIDKEGNETDKAV 585

Query: 556  AWEKAFIQLIKDEIVPMVQAQNLTLAFSSESSIQEELKRESTADVITILVSYLVMFAYIS 377
            AWEKAFIQL+K+E++PMVQ++NLTL+FSSESSI+EELKRESTADVITIL+SYLVMFAYIS
Sbjct: 586  AWEKAFIQLVKNELLPMVQSKNLTLSFSSESSIEEELKRESTADVITILISYLVMFAYIS 645

Query: 376  ITLGEKHQLSSIFXXXXXXXXXXXXXXXXXXXXXSIGFYSSIGVKSTLIIMEVIPFLVLA 197
            +TLG+   LSS +                     S+GF+S+IGVKSTLIIMEVIPFLVLA
Sbjct: 646  LTLGDTPHLSSFYISSKVLLGLSGVLLVMLSVLGSVGFFSAIGVKSTLIIMEVIPFLVLA 705

Query: 196  VGVDNMCILVHAINRQPLELLLEERISNALTEVGPSITLASLSEVLAFAVGSFIPMPACR 17
            VGVDNMCILVHA+ RQP+EL LE RISNAL EVGPSITLASLSEVLAFAVGSFIPMPACR
Sbjct: 706  VGVDNMCILVHAVKRQPMELPLEGRISNALVEVGPSITLASLSEVLAFAVGSFIPMPACR 765

Query: 16   VFSMF 2
            VFSMF
Sbjct: 766  VFSMF 770


>ref|XP_006386140.1| hypothetical protein POPTR_0002s01050g [Populus trichocarpa]
            gi|550344028|gb|ERP63937.1| hypothetical protein
            POPTR_0002s01050g [Populus trichocarpa]
          Length = 987

 Score =  930 bits (2404), Expect = 0.0
 Identities = 463/725 (63%), Positives = 556/725 (76%), Gaps = 3/725 (0%)
 Frame = -1

Query: 2167 ERYAKGYCSMYGICGQRSDGKALNCPNYTRSIKPDELLSSKIQSLCPTITGNVCCTAEQF 1988
            ER+++ YC+MY ICG R DGK +NCP  + S+KPD+LLS KIQSLCPTITGNVCC+  QF
Sbjct: 46   ERHSEEYCAMYDICGAREDGKVVNCPFGSPSVKPDDLLSQKIQSLCPTITGNVCCSEAQF 105

Query: 1987 ETLREQVQQAVPLLVGCPACLRNFLNLFCELSCSPDQSLFINVTSAKQVNGSMTVDSIDF 1808
            ETLR QVQQA+P LVGCPACLRNFLNLFCEL+CSP QS+FINVTS  +V G++TV  IDF
Sbjct: 106  ETLRSQVQQAIPFLVGCPACLRNFLNLFCELTCSPHQSMFINVTSTDKVEGNLTVSGIDF 165

Query: 1807 FVTHQFGEQLFNSCKDVKFGTMNTRSMDFVGAGAQNYSEWFTFLGRQANLNEPGSPYPIT 1628
            +V   FGE L+ SCKDVKFGTMN+R+++F+GAGA+N++EW+ F+GR+A LN PGSPY +T
Sbjct: 166  YVYDSFGEGLYESCKDVKFGTMNSRALNFIGAGAKNFTEWYAFIGRRAPLNVPGSPYAMT 225

Query: 1627 FTSYISGLSGIKPMNATTYSCGDSSMGFSCGDCPSSAVCIDSLSPAPHVKQSCSIKLISL 1448
            F       SG+KPMN +TYSCGD S+G SCGDCP S VC ++  P  H   SC++++ SL
Sbjct: 226  FKPSAPESSGMKPMNVSTYSCGDISLGCSCGDCPQSPVCANTDPPPHHEGASCAVRIGSL 285

Query: 1447 KVKCLDFSLVIIYLFIVCAFLVWNFVYIKK-KEGPFRTKPLLNVK--GESSNDKQETHVS 1277
            K KC+DF L I+Y+ +V  FL W   + K+ ++   R  P+ N+K  GE +  K E    
Sbjct: 286  KAKCVDFILTILYVILVSIFLGWGLFHRKRERDQSSRMNPVSNIKDSGEVTGKKDENLPM 345

Query: 1276 QTTAMVPSGLKAHDPSVIQLYMSNFFRKYGTFVSKNPTXXXXXXXXXXXXXXXXXIHFKV 1097
            Q     P        S++Q YMS F+R YGT+V++NP                  I FKV
Sbjct: 346  QMLEDSPQTGSRVQLSIVQGYMSKFYRCYGTWVARNPILVLSLSLAVILLLCLGLIRFKV 405

Query: 1096 ETRPEKLWVGPGSRAAKEKQYFDSHLAPFYRIEQILLASVSPSVGERPPSIVTEQNLKLL 917
            ETRPEKLWVGPGS+ A+EK++FD+HLAPFYRIEQ++LA+V  +  ++ PSIVTE N+KLL
Sbjct: 406  ETRPEKLWVGPGSKVAEEKRFFDTHLAPFYRIEQLILATVPEAGAQKRPSIVTENNIKLL 465

Query: 916  FEIQKKVDNLHANYSGSMVSLSDICLKPLGNDCATQSVLQYFQMDLQNYDTYGGLTHAEY 737
            FEIQKKVD +HANYSG+MVSL DICLKPL  DCATQSVLQYFQMD QN D YGG+ H  Y
Sbjct: 466  FEIQKKVDGIHANYSGTMVSLPDICLKPLDKDCATQSVLQYFQMDPQNLDNYGGVEHVNY 525

Query: 736  CFEHFSSDQTCLSAFTAPLDPSTALGGFSGNNYSEASAFVITYPVNNVLDETSIEFRNAV 557
            C +H+SS  TC SAF APLDPSTALGGFSGNNYSEASAF++TYPVNNV+D+   E   AV
Sbjct: 526  CLQHYSSADTCRSAFKAPLDPSTALGGFSGNNYSEASAFIVTYPVNNVIDKEGNETDKAV 585

Query: 556  AWEKAFIQLIKDEIVPMVQAQNLTLAFSSESSIQEELKRESTADVITILVSYLVMFAYIS 377
            AWEKAFIQL+K+E++PMVQ++NLTL+FSSESSI+EELKRESTADVITIL+SYLVMFAYIS
Sbjct: 586  AWEKAFIQLVKNELLPMVQSKNLTLSFSSESSIEEELKRESTADVITILISYLVMFAYIS 645

Query: 376  ITLGEKHQLSSIFXXXXXXXXXXXXXXXXXXXXXSIGFYSSIGVKSTLIIMEVIPFLVLA 197
            +TLG+   LSS +                     S+GF+S+IGVKSTLIIMEVIPFLVLA
Sbjct: 646  LTLGDTPHLSSFYISSKVLLGLSGVLLVMLSVLGSVGFFSAIGVKSTLIIMEVIPFLVLA 705

Query: 196  VGVDNMCILVHAINRQPLELLLEERISNALTEVGPSITLASLSEVLAFAVGSFIPMPACR 17
            VGVDNMCILVHA+ RQP+EL LE RISNAL EVGPSITLASLSEVLAFAVGSFIPMPACR
Sbjct: 706  VGVDNMCILVHAVKRQPMELPLEGRISNALVEVGPSITLASLSEVLAFAVGSFIPMPACR 765

Query: 16   VFSMF 2
            VFSMF
Sbjct: 766  VFSMF 770


>gb|EXB56311.1| Niemann-Pick C1 protein [Morus notabilis]
          Length = 1455

 Score =  930 bits (2403), Expect = 0.0
 Identities = 467/723 (64%), Positives = 564/723 (78%), Gaps = 10/723 (1%)
 Frame = -1

Query: 2140 MYGICGQRSDGKALNCPNYTRSIKPDELLSSKIQSLCPTITGNVCCTAEQFETLREQVQQ 1961
            MY ICG+R+DGK LNCP  + S+KPD+LLSSKIQSLCPTITGNVCCT  QF+TLR QVQQ
Sbjct: 1    MYDICGKRTDGKVLNCPRGSPSVKPDDLLSSKIQSLCPTITGNVCCTEAQFDTLRTQVQQ 60

Query: 1960 AVPLLVGCPACLRNFLNLFCELSCSPDQSLFINVTSAKQVNGSMTVDSIDFFVTHQFGEQ 1781
            A+P LVGCPACLRNFLNLFCEL+CSP+QSLFINV+S  QVN +MTV+ IDF++   FGE 
Sbjct: 61   AIPFLVGCPACLRNFLNLFCELTCSPNQSLFINVSSVLQVNKNMTVNGIDFYINDAFGEG 120

Query: 1780 LFNSCKDVKFGTMNTRSMDFVGAGAQNYSEWFTFLGRQANLNEPGSPYPITFTSYISGLS 1601
            L++SCKDVKFGTMN+R+++F+GAGA+N+ EWF F+GR+A LN PGSPY ITF S I   S
Sbjct: 121  LYDSCKDVKFGTMNSRALEFIGAGAKNFREWFAFIGRRAPLNVPGSPYAITFRSSIPETS 180

Query: 1600 GIKPMNATTYSCGDSSMGFSCGDCPSSAVCIDSLSPAPHVKQSCSIKLISLKVKCLDFSL 1421
            G+KPMN +TYSCGD S+G SCGDCP S VC +S+SP  +   SCS+++ SLK KC+D ++
Sbjct: 181  GVKPMNVSTYSCGDISLGCSCGDCPLSPVCANSVSPPSNEGGSCSVRIGSLKAKCIDIAV 240

Query: 1420 VIIYLFIVCAFLVWNFVYI--KKKEGPFRTKPLLNVK--GE--SSNDKQETHVS----QT 1271
             I+Y+ +V AFL W   Y+  +K+  P R KP  +    GE  S N ++E ++S    Q 
Sbjct: 241  AILYIVLVSAFLGWRLFYLNRQKENVPSRAKPFWHAMEGGELHSVNQQKEENLSIQMLQD 300

Query: 1270 TAMVPSGLKAHDPSVIQLYMSNFFRKYGTFVSKNPTXXXXXXXXXXXXXXXXXIHFKVET 1091
               + +G++    S++Q YMSNF+R YG +V+KNP                  I FKVET
Sbjct: 301  APQIRNGVQL---SIVQGYMSNFYRMYGIWVAKNPILVLCSSLAIVFVLCLGLIRFKVET 357

Query: 1090 RPEKLWVGPGSRAAKEKQYFDSHLAPFYRIEQILLASVSPSVGERPPSIVTEQNLKLLFE 911
            RPEKLWVGPGS+AA EKQ+FD+HLAPFYRIEQ++LA++ P V  + PSIVTE N+KLLFE
Sbjct: 358  RPEKLWVGPGSKAAGEKQFFDNHLAPFYRIEQLVLATI-PDVDGKSPSIVTENNIKLLFE 416

Query: 910  IQKKVDNLHANYSGSMVSLSDICLKPLGNDCATQSVLQYFQMDLQNYDTYGGLTHAEYCF 731
            IQKKVD +HANYSGS+VSL+DIC+KPL  DCATQSVLQYF+MD  NYD YGG+ H +YCF
Sbjct: 417  IQKKVDGIHANYSGSVVSLADICMKPLDQDCATQSVLQYFKMDPDNYDNYGGVEHLKYCF 476

Query: 730  EHFSSDQTCLSAFTAPLDPSTALGGFSGNNYSEASAFVITYPVNNVLDETSIEFRNAVAW 551
            EH+SS   C+SAF APLDPSTALGGFSGNNYSEASAF+ITYPVNN +D+       AVAW
Sbjct: 477  EHYSSAAKCMSAFKAPLDPSTALGGFSGNNYSEASAFIITYPVNNAVDKRGNASEKAVAW 536

Query: 550  EKAFIQLIKDEIVPMVQAQNLTLAFSSESSIQEELKRESTADVITILVSYLVMFAYISIT 371
            EKAFIQ+ KDE++ +VQ++NLTL+FSSESSI+EELKREST D ITIL+SYLVMFAYIS+T
Sbjct: 537  EKAFIQMSKDELLQLVQSKNLTLSFSSESSIEEELKRESTTDAITILISYLVMFAYISLT 596

Query: 370  LGEKHQLSSIFXXXXXXXXXXXXXXXXXXXXXSIGFYSSIGVKSTLIIMEVIPFLVLAVG 191
            LG+   LSS +                     S+GF+S++GVKSTLIIMEVIPFLVLAVG
Sbjct: 597  LGDTPHLSSFYISSKVLLGLSGVVLVMLSVLGSVGFFSALGVKSTLIIMEVIPFLVLAVG 656

Query: 190  VDNMCILVHAINRQPLELLLEERISNALTEVGPSITLASLSEVLAFAVGSFIPMPACRVF 11
            VDNMCILVHA+ RQP+EL LEERISNAL EVGPSITLASLSEVLAFAVG+FIPMPACRVF
Sbjct: 657  VDNMCILVHAVKRQPMELPLEERISNALVEVGPSITLASLSEVLAFAVGTFIPMPACRVF 716

Query: 10   SMF 2
            SMF
Sbjct: 717  SMF 719


>ref|XP_002307793.2| patched family protein [Populus trichocarpa]
            gi|550339849|gb|EEE94789.2| patched family protein
            [Populus trichocarpa]
          Length = 1299

 Score =  926 bits (2394), Expect = 0.0
 Identities = 458/727 (62%), Positives = 557/727 (76%), Gaps = 3/727 (0%)
 Frame = -1

Query: 2173 AQERYAKGYCSMYGICGQRSDGKALNCPNYTRSIKPDELLSSKIQSLCPTITGNVCCTAE 1994
            ++ER+++ YC+MY ICG R DGK LNCP  + S+KPD+LLS KIQSLCPTITGNVCC+  
Sbjct: 49   SRERHSEEYCAMYDICGAREDGKVLNCPYGSPSVKPDDLLSQKIQSLCPTITGNVCCSEA 108

Query: 1993 QFETLREQVQQAVPLLVGCPACLRNFLNLFCELSCSPDQSLFINVTSAKQVNGSMTVDSI 1814
            QF+TLR QVQQA+P LVGCPACLRNFLNLFCEL+CSP QS FINVT+  +V G++TV  I
Sbjct: 109  QFDTLRSQVQQAIPFLVGCPACLRNFLNLFCELTCSPHQSTFINVTTTAKVKGNLTVSGI 168

Query: 1813 DFFVTHQFGEQLFNSCKDVKFGTMNTRSMDFVGAGAQNYSEWFTFLGRQANLNEPGSPYP 1634
            DF+ +  FGE L+ SCKDVKFGTMNTR+++F+GAGAQN++EW+ F+GR+A L+ PGSPY 
Sbjct: 169  DFYASDAFGEGLYESCKDVKFGTMNTRALNFIGAGAQNFTEWYAFIGRRAPLDVPGSPYA 228

Query: 1633 ITFTSYISGLSGIKPMNATTYSCGDSSMGFSCGDCPSSAVCIDSLSPAPHVKQSCSIKLI 1454
            +TF       SGIKPMN +TYSCGD S+G SCGDCP S VC ++  P  H   SC++++ 
Sbjct: 229  MTFKPTAPESSGIKPMNVSTYSCGDISLGCSCGDCPQSPVCANTAPPPHHEGGSCAVRIG 288

Query: 1453 SLKVKCLDFSLVIIYLFIVCAFLVWNFVYIKKKEGPF-RTKPLLNVK--GESSNDKQETH 1283
            SLK KC+DF+L I+Y+ ++  FL W   + K++     R  PL ++K  GE    K E  
Sbjct: 289  SLKAKCVDFALTILYIILISMFLGWGLFHRKRERNQTSRMNPLSDIKDSGEVIRKKDENL 348

Query: 1282 VSQTTAMVPSGLKAHDPSVIQLYMSNFFRKYGTFVSKNPTXXXXXXXXXXXXXXXXXIHF 1103
             +Q     P        S++Q YMS F+R+YGT+V++NP                  I F
Sbjct: 349  PAQMVEDSPQTGSRVQLSIVQGYMSKFYRRYGTWVARNPILVLSLSLAVILLLCVGLIRF 408

Query: 1102 KVETRPEKLWVGPGSRAAKEKQYFDSHLAPFYRIEQILLASVSPSVGERPPSIVTEQNLK 923
            KVETRPEKLWVGPGS+ A+EK++FD+HLAPFYRIEQ++LA+V  +  ++ PSIVTE N+K
Sbjct: 409  KVETRPEKLWVGPGSKVAEEKRFFDTHLAPFYRIEQLILATVPDAGAQKLPSIVTEDNIK 468

Query: 922  LLFEIQKKVDNLHANYSGSMVSLSDICLKPLGNDCATQSVLQYFQMDLQNYDTYGGLTHA 743
            LLFEIQKKVD + ANYSGSMVSL+DIC+KPL  DCATQSVLQYFQMD QN + YGG+ H 
Sbjct: 469  LLFEIQKKVDGIRANYSGSMVSLTDICMKPLDKDCATQSVLQYFQMDPQNLENYGGVEHV 528

Query: 742  EYCFEHFSSDQTCLSAFTAPLDPSTALGGFSGNNYSEASAFVITYPVNNVLDETSIEFRN 563
             YC +H++S  TC SAF APLDPST+LGGFSGNNYSEASAF++TYPVNNV+D+   E   
Sbjct: 529  NYCLQHYTSADTCRSAFKAPLDPSTSLGGFSGNNYSEASAFIVTYPVNNVIDKEGNETDK 588

Query: 562  AVAWEKAFIQLIKDEIVPMVQAQNLTLAFSSESSIQEELKRESTADVITILVSYLVMFAY 383
            AVAWEKAFIQL+K+E++PMVQ++NLTL+FSSESSI+EELKRESTADVITIL+SYLVMFAY
Sbjct: 589  AVAWEKAFIQLVKNELLPMVQSKNLTLSFSSESSIEEELKRESTADVITILISYLVMFAY 648

Query: 382  ISITLGEKHQLSSIFXXXXXXXXXXXXXXXXXXXXXSIGFYSSIGVKSTLIIMEVIPFLV 203
            IS+TLG+   LSS +                     S+GF+S+IGVKSTLIIMEVIPFLV
Sbjct: 649  ISLTLGDAPHLSSFYISSKVLLGLSGVMLVMLSVLGSVGFFSAIGVKSTLIIMEVIPFLV 708

Query: 202  LAVGVDNMCILVHAINRQPLELLLEERISNALTEVGPSITLASLSEVLAFAVGSFIPMPA 23
            LAVGVDNMCILVHA+ RQPLEL LE RISNAL EVGPSITLASLSEVLAFA GSFIPMPA
Sbjct: 709  LAVGVDNMCILVHAVKRQPLELPLEGRISNALVEVGPSITLASLSEVLAFAAGSFIPMPA 768

Query: 22   CRVFSMF 2
            CRVFSMF
Sbjct: 769  CRVFSMF 775


>ref|XP_006383771.1| hypothetical protein POPTR_0005s27320g [Populus trichocarpa]
            gi|566173518|ref|XP_006383772.1| hypothetical protein
            POPTR_0005s27320g [Populus trichocarpa]
            gi|550339847|gb|ERP61568.1| hypothetical protein
            POPTR_0005s27320g [Populus trichocarpa]
            gi|550339848|gb|ERP61569.1| hypothetical protein
            POPTR_0005s27320g [Populus trichocarpa]
          Length = 1287

 Score =  926 bits (2394), Expect = 0.0
 Identities = 458/727 (62%), Positives = 557/727 (76%), Gaps = 3/727 (0%)
 Frame = -1

Query: 2173 AQERYAKGYCSMYGICGQRSDGKALNCPNYTRSIKPDELLSSKIQSLCPTITGNVCCTAE 1994
            ++ER+++ YC+MY ICG R DGK LNCP  + S+KPD+LLS KIQSLCPTITGNVCC+  
Sbjct: 49   SRERHSEEYCAMYDICGAREDGKVLNCPYGSPSVKPDDLLSQKIQSLCPTITGNVCCSEA 108

Query: 1993 QFETLREQVQQAVPLLVGCPACLRNFLNLFCELSCSPDQSLFINVTSAKQVNGSMTVDSI 1814
            QF+TLR QVQQA+P LVGCPACLRNFLNLFCEL+CSP QS FINVT+  +V G++TV  I
Sbjct: 109  QFDTLRSQVQQAIPFLVGCPACLRNFLNLFCELTCSPHQSTFINVTTTAKVKGNLTVSGI 168

Query: 1813 DFFVTHQFGEQLFNSCKDVKFGTMNTRSMDFVGAGAQNYSEWFTFLGRQANLNEPGSPYP 1634
            DF+ +  FGE L+ SCKDVKFGTMNTR+++F+GAGAQN++EW+ F+GR+A L+ PGSPY 
Sbjct: 169  DFYASDAFGEGLYESCKDVKFGTMNTRALNFIGAGAQNFTEWYAFIGRRAPLDVPGSPYA 228

Query: 1633 ITFTSYISGLSGIKPMNATTYSCGDSSMGFSCGDCPSSAVCIDSLSPAPHVKQSCSIKLI 1454
            +TF       SGIKPMN +TYSCGD S+G SCGDCP S VC ++  P  H   SC++++ 
Sbjct: 229  MTFKPTAPESSGIKPMNVSTYSCGDISLGCSCGDCPQSPVCANTAPPPHHEGGSCAVRIG 288

Query: 1453 SLKVKCLDFSLVIIYLFIVCAFLVWNFVYIKKKEGPF-RTKPLLNVK--GESSNDKQETH 1283
            SLK KC+DF+L I+Y+ ++  FL W   + K++     R  PL ++K  GE    K E  
Sbjct: 289  SLKAKCVDFALTILYIILISMFLGWGLFHRKRERNQTSRMNPLSDIKDSGEVIRKKDENL 348

Query: 1282 VSQTTAMVPSGLKAHDPSVIQLYMSNFFRKYGTFVSKNPTXXXXXXXXXXXXXXXXXIHF 1103
             +Q     P        S++Q YMS F+R+YGT+V++NP                  I F
Sbjct: 349  PAQMVEDSPQTGSRVQLSIVQGYMSKFYRRYGTWVARNPILVLSLSLAVILLLCVGLIRF 408

Query: 1102 KVETRPEKLWVGPGSRAAKEKQYFDSHLAPFYRIEQILLASVSPSVGERPPSIVTEQNLK 923
            KVETRPEKLWVGPGS+ A+EK++FD+HLAPFYRIEQ++LA+V  +  ++ PSIVTE N+K
Sbjct: 409  KVETRPEKLWVGPGSKVAEEKRFFDTHLAPFYRIEQLILATVPDAGAQKLPSIVTEDNIK 468

Query: 922  LLFEIQKKVDNLHANYSGSMVSLSDICLKPLGNDCATQSVLQYFQMDLQNYDTYGGLTHA 743
            LLFEIQKKVD + ANYSGSMVSL+DIC+KPL  DCATQSVLQYFQMD QN + YGG+ H 
Sbjct: 469  LLFEIQKKVDGIRANYSGSMVSLTDICMKPLDKDCATQSVLQYFQMDPQNLENYGGVEHV 528

Query: 742  EYCFEHFSSDQTCLSAFTAPLDPSTALGGFSGNNYSEASAFVITYPVNNVLDETSIEFRN 563
             YC +H++S  TC SAF APLDPST+LGGFSGNNYSEASAF++TYPVNNV+D+   E   
Sbjct: 529  NYCLQHYTSADTCRSAFKAPLDPSTSLGGFSGNNYSEASAFIVTYPVNNVIDKEGNETDK 588

Query: 562  AVAWEKAFIQLIKDEIVPMVQAQNLTLAFSSESSIQEELKRESTADVITILVSYLVMFAY 383
            AVAWEKAFIQL+K+E++PMVQ++NLTL+FSSESSI+EELKRESTADVITIL+SYLVMFAY
Sbjct: 589  AVAWEKAFIQLVKNELLPMVQSKNLTLSFSSESSIEEELKRESTADVITILISYLVMFAY 648

Query: 382  ISITLGEKHQLSSIFXXXXXXXXXXXXXXXXXXXXXSIGFYSSIGVKSTLIIMEVIPFLV 203
            IS+TLG+   LSS +                     S+GF+S+IGVKSTLIIMEVIPFLV
Sbjct: 649  ISLTLGDAPHLSSFYISSKVLLGLSGVMLVMLSVLGSVGFFSAIGVKSTLIIMEVIPFLV 708

Query: 202  LAVGVDNMCILVHAINRQPLELLLEERISNALTEVGPSITLASLSEVLAFAVGSFIPMPA 23
            LAVGVDNMCILVHA+ RQPLEL LE RISNAL EVGPSITLASLSEVLAFA GSFIPMPA
Sbjct: 709  LAVGVDNMCILVHAVKRQPLELPLEGRISNALVEVGPSITLASLSEVLAFAAGSFIPMPA 768

Query: 22   CRVFSMF 2
            CRVFSMF
Sbjct: 769  CRVFSMF 775


>ref|XP_006473797.1| PREDICTED: niemann-Pick C1 protein-like isoform X2 [Citrus sinensis]
          Length = 1294

 Score =  926 bits (2392), Expect = 0.0
 Identities = 457/726 (62%), Positives = 552/726 (76%), Gaps = 5/726 (0%)
 Frame = -1

Query: 2164 RYAKGYCSMYGICGQRSDGKALNCPNYTRSIKPDELLSSKIQSLCPTITGNVCCTAEQFE 1985
            ++ + +C+MY ICG RSD K LNCP    S+KPD+LLSSK+QSLCPTITGNVCCT +QF+
Sbjct: 47   KHVEEFCAMYDICGARSDRKVLNCPYNIPSVKPDDLLSSKVQSLCPTITGNVCCTEDQFD 106

Query: 1984 TLREQVQQAVPLLVGCPACLRNFLNLFCELSCSPDQSLFINVTSAKQVNGSMTVDSIDFF 1805
            TLR QVQQA+P LVGCPACLRNFLNLFCEL+CSP+QSLFINVTS  +V+ ++TVD ID++
Sbjct: 107  TLRTQVQQAIPFLVGCPACLRNFLNLFCELTCSPNQSLFINVTSVSKVSNNLTVDGIDYY 166

Query: 1804 VTHQFGEQLFNSCKDVKFGTMNTRSMDFVGAGAQNYSEWFTFLGRQANLNEPGSPYPITF 1625
            +T  FG+ L+ SCKDVKFGTMNTR++DF+G GAQN+ +WF F+GR+A  N PGSPY I F
Sbjct: 167  ITDTFGQGLYESCKDVKFGTMNTRALDFIGGGAQNFKDWFAFIGRRAAANLPGSPYTIKF 226

Query: 1624 TSYISGLSGIKPMNATTYSCGDSSMGFSCGDCPSSAVCIDSLSPAPHVKQSCSIKLISLK 1445
                  LSG+ PMN + YSC D S+G SCGDC SS VC  S +P PH   SCS+K+ SL 
Sbjct: 227  WPSAPELSGMIPMNVSAYSCADGSLGCSCGDCTSSPVC-SSTAPPPHKSSSCSVKMGSLN 285

Query: 1444 VKCLDFSLVIIYLFIVCAFLVWNFVYIKKKEG-PFRTKPLLNVKGESSNDKQETHVSQTT 1268
             KC+DF+L I+Y+ +V  F  W F + K++    FR KPL+N    S     E    +  
Sbjct: 286  AKCVDFALAILYIILVSLFFGWGFFHRKRERSRSFRMKPLVNAMDGSELHSVERQKEENL 345

Query: 1267 AM----VPSGLKAHDPSVIQLYMSNFFRKYGTFVSKNPTXXXXXXXXXXXXXXXXXIHFK 1100
             M     P        S++Q YMSNF+RKYG +V++NPT                 I F+
Sbjct: 346  PMQMLGTPRTRNRIQLSIVQGYMSNFYRKYGKWVARNPTLVLSLSMALVLLLCLGLIRFE 405

Query: 1099 VETRPEKLWVGPGSRAAKEKQYFDSHLAPFYRIEQILLASVSPSVGERPPSIVTEQNLKL 920
            VETRPEKLWVGPGSRAA+EK +FDSHLAPFYRIE+++LA++  +     PSIVTE N+KL
Sbjct: 406  VETRPEKLWVGPGSRAAEEKLFFDSHLAPFYRIEELILATIPDTTHGNLPSIVTESNIKL 465

Query: 919  LFEIQKKVDNLHANYSGSMVSLSDICLKPLGNDCATQSVLQYFQMDLQNYDTYGGLTHAE 740
            LFEIQKK+D L ANYSGSM+SL+DIC+KPLG DCATQSVLQYF+MD +N+D +GG+ H +
Sbjct: 466  LFEIQKKIDGLRANYSGSMISLTDICMKPLGQDCATQSVLQYFKMDPKNFDDFGGVEHVK 525

Query: 739  YCFEHFSSDQTCLSAFTAPLDPSTALGGFSGNNYSEASAFVITYPVNNVLDETSIEFRNA 560
            YCF+H++S ++C+SAF  PLDPSTALGGFSGNNYSEASAFV+TYPVNN +D    E + A
Sbjct: 526  YCFQHYTSTESCMSAFKGPLDPSTALGGFSGNNYSEASAFVVTYPVNNAVDREGNETKKA 585

Query: 559  VAWEKAFIQLIKDEIVPMVQAQNLTLAFSSESSIQEELKRESTADVITILVSYLVMFAYI 380
            VAWEKAF+QL KDE++PMVQ++NLTLAFSSESSI+EELKRESTAD ITI++SYLVMFAYI
Sbjct: 586  VAWEKAFVQLAKDELLPMVQSKNLTLAFSSESSIEEELKRESTADAITIVISYLVMFAYI 645

Query: 379  SITLGEKHQLSSIFXXXXXXXXXXXXXXXXXXXXXSIGFYSSIGVKSTLIIMEVIPFLVL 200
            S+TLG+   LSS +                     S+GF+S+IGVKSTLIIMEVIPFLVL
Sbjct: 646  SLTLGDTPHLSSFYISSKVLLGLSGVVLVMLSVLGSVGFFSAIGVKSTLIIMEVIPFLVL 705

Query: 199  AVGVDNMCILVHAINRQPLELLLEERISNALTEVGPSITLASLSEVLAFAVGSFIPMPAC 20
            AVGVDNMCILVHA+ RQ LEL LE RISNAL EVGPSITLASLSEVLAFAVGSFIPMPAC
Sbjct: 706  AVGVDNMCILVHAVKRQQLELPLETRISNALVEVGPSITLASLSEVLAFAVGSFIPMPAC 765

Query: 19   RVFSMF 2
            RVFSMF
Sbjct: 766  RVFSMF 771


>ref|XP_006435367.1| hypothetical protein CICLE_v10000039mg [Citrus clementina]
            gi|568839657|ref|XP_006473796.1| PREDICTED: niemann-Pick
            C1 protein-like isoform X1 [Citrus sinensis]
            gi|557537489|gb|ESR48607.1| hypothetical protein
            CICLE_v10000039mg [Citrus clementina]
          Length = 1296

 Score =  925 bits (2390), Expect = 0.0
 Identities = 457/728 (62%), Positives = 552/728 (75%), Gaps = 7/728 (0%)
 Frame = -1

Query: 2164 RYAKGYCSMYGICGQRSDGKALNCPNYTRSIKPDELLSSKIQSLCPTITGNVCCTAEQFE 1985
            ++ + +C+MY ICG RSD K LNCP    S+KPD+LLSSK+QSLCPTITGNVCCT +QF+
Sbjct: 47   KHVEEFCAMYDICGARSDRKVLNCPYNIPSVKPDDLLSSKVQSLCPTITGNVCCTEDQFD 106

Query: 1984 TLREQVQQAVPLLVGCPACLRNFLNLFCELSCSPDQSLFINVTSAKQVNGSMTVDSIDFF 1805
            TLR QVQQA+P LVGCPACLRNFLNLFCEL+CSP+QSLFINVTS  +V+ ++TVD ID++
Sbjct: 107  TLRTQVQQAIPFLVGCPACLRNFLNLFCELTCSPNQSLFINVTSVSKVSNNLTVDGIDYY 166

Query: 1804 VTHQFGEQLFNSCKDVKFGTMNTRSMDFVGAGAQNYSEWFTFLGRQANLNEPGSPYPITF 1625
            +T  FG+ L+ SCKDVKFGTMNTR++DF+G GAQN+ +WF F+GR+A  N PGSPY I F
Sbjct: 167  ITDTFGQGLYESCKDVKFGTMNTRALDFIGGGAQNFKDWFAFIGRRAAANLPGSPYTIKF 226

Query: 1624 TSYISGLSGIKPMNATTYSCGDSSMGFSCGDCPSSAVCIDSLSPAPHVKQSCSIKLISLK 1445
                  LSG+ PMN + YSC D S+G SCGDC SS VC  S +P PH   SCS+K+ SL 
Sbjct: 227  WPSAPELSGMIPMNVSAYSCADGSLGCSCGDCTSSPVC-SSTAPPPHKSSSCSVKMGSLN 285

Query: 1444 VKCLDFSLVIIYLFIVCAFLVWNFVYIKKKEG-PFRTKPLLNVKGESSNDKQETHVSQTT 1268
             KC+DF+L I+Y+ +V  F  W F + K++    FR KPL+N    S     E    +  
Sbjct: 286  AKCVDFALAILYIILVSLFFGWGFFHRKRERSRSFRMKPLVNAMDGSELHSVERQKEENL 345

Query: 1267 AM------VPSGLKAHDPSVIQLYMSNFFRKYGTFVSKNPTXXXXXXXXXXXXXXXXXIH 1106
             M       P        S++Q YMSNF+RKYG +V++NPT                 I 
Sbjct: 346  PMQVQMLGTPRTRNRIQLSIVQGYMSNFYRKYGKWVARNPTLVLSLSMALVLLLCLGLIR 405

Query: 1105 FKVETRPEKLWVGPGSRAAKEKQYFDSHLAPFYRIEQILLASVSPSVGERPPSIVTEQNL 926
            F+VETRPEKLWVGPGSRAA+EK +FDSHLAPFYRIE+++LA++  +     PSIVTE N+
Sbjct: 406  FEVETRPEKLWVGPGSRAAEEKLFFDSHLAPFYRIEELILATIPDTTHGNLPSIVTESNI 465

Query: 925  KLLFEIQKKVDNLHANYSGSMVSLSDICLKPLGNDCATQSVLQYFQMDLQNYDTYGGLTH 746
            KLLFEIQKK+D L ANYSGSM+SL+DIC+KPLG DCATQSVLQYF+MD +N+D +GG+ H
Sbjct: 466  KLLFEIQKKIDGLRANYSGSMISLTDICMKPLGQDCATQSVLQYFKMDPKNFDDFGGVEH 525

Query: 745  AEYCFEHFSSDQTCLSAFTAPLDPSTALGGFSGNNYSEASAFVITYPVNNVLDETSIEFR 566
             +YCF+H++S ++C+SAF  PLDPSTALGGFSGNNYSEASAFV+TYPVNN +D    E +
Sbjct: 526  VKYCFQHYTSTESCMSAFKGPLDPSTALGGFSGNNYSEASAFVVTYPVNNAVDREGNETK 585

Query: 565  NAVAWEKAFIQLIKDEIVPMVQAQNLTLAFSSESSIQEELKRESTADVITILVSYLVMFA 386
             AVAWEKAF+QL KDE++PMVQ++NLTLAFSSESSI+EELKRESTAD ITI++SYLVMFA
Sbjct: 586  KAVAWEKAFVQLAKDELLPMVQSKNLTLAFSSESSIEEELKRESTADAITIVISYLVMFA 645

Query: 385  YISITLGEKHQLSSIFXXXXXXXXXXXXXXXXXXXXXSIGFYSSIGVKSTLIIMEVIPFL 206
            YIS+TLG+   LSS +                     S+GF+S+IGVKSTLIIMEVIPFL
Sbjct: 646  YISLTLGDTPHLSSFYISSKVLLGLSGVVLVMLSVLGSVGFFSAIGVKSTLIIMEVIPFL 705

Query: 205  VLAVGVDNMCILVHAINRQPLELLLEERISNALTEVGPSITLASLSEVLAFAVGSFIPMP 26
            VLAVGVDNMCILVHA+ RQ LEL LE RISNAL EVGPSITLASLSEVLAFAVGSFIPMP
Sbjct: 706  VLAVGVDNMCILVHAVKRQQLELPLETRISNALVEVGPSITLASLSEVLAFAVGSFIPMP 765

Query: 25   ACRVFSMF 2
            ACRVFSMF
Sbjct: 766  ACRVFSMF 773


>ref|XP_004976504.1| PREDICTED: niemann-Pick C1 protein-like [Setaria italica]
          Length = 1272

 Score =  921 bits (2381), Expect = 0.0
 Identities = 468/747 (62%), Positives = 571/747 (76%), Gaps = 7/747 (0%)
 Frame = -1

Query: 2221 IQVTLIFFSGNFQPSYAQERY-AKGYCSMYGICGQRSDGKALNCPNYTRSIKPDELLSSK 2045
            +Q++L+ F  + Q S       A+GYCSMYGIC QRSDGK LNC N T+++KPD L SS+
Sbjct: 2    MQISLLAFPISAQQSNGSRVVPAEGYCSMYGICAQRSDGKVLNCANATKAVKPDTLFSSR 61

Query: 2044 IQSLCPTITGNVCCTAEQFETLREQVQQAVPLLVGCPACLRNFLNLFCELSCSPDQSLFI 1865
            IQSLCPTITGNVCCTA+QF+TL +QVQQAVP LVGCPACLRNFLNLFCE+SCSP+QSLFI
Sbjct: 62   IQSLCPTITGNVCCTADQFDTLHQQVQQAVPFLVGCPACLRNFLNLFCEMSCSPNQSLFI 121

Query: 1864 NVTSAKQVNGSMTVDSIDFFVTHQFGEQLFNSCKDVKFGTMNTRSMDFVGAGAQNYSEWF 1685
            NVTS KQ+N +MTVD ID++VT  +GE+L+NSCKDVKFGT+NTR+MDF+G GA+ Y EW 
Sbjct: 122  NVTSVKQINSTMTVDGIDYYVTTNYGEELYNSCKDVKFGTLNTRAMDFLGGGAKTYKEWL 181

Query: 1684 TFLGRQANLNEPGSPYPITFTSYISGLSGIKPMNATTYSCGDSSMGFSCGDCPSSAVCID 1505
             F+GRQAN NEPGSPY ITF S  S  SG+KP+N+T YSCGD S+G SCGDCPSS+VC  
Sbjct: 182  AFIGRQANPNEPGSPYLITFRSDFSDSSGVKPLNSTIYSCGDPSLGCSCGDCPSSSVCTG 241

Query: 1504 SLSPAPHVKQSCSIKLISLKVKCLDFSLVIIYLFIVCAFLVWNFVYIK--KKEGPFRTKP 1331
            SL P  +   SCS+K+ SLK KCLDFSLV+IYL ++CAFL+W  ++    +     +TKP
Sbjct: 242  SLLPQLNTDTSCSVKMGSLKAKCLDFSLVVIYLALLCAFLLWGLLHRARGRTASSLQTKP 301

Query: 1330 LLNV--KGESSNDKQETHVS-QTTAMVPSGLKAHDPSVIQLYMSNFFRKYGTFVSKNPTX 1160
            L N   K +S+ + +  H S Q +    S +K   PS++Q YMS FFRK+G FV+++P  
Sbjct: 302  LKNSDDKSDSNQNGKSPHNSVQVSEAASSTVKPSYPSIVQTYMSIFFRKHGIFVARHPLL 361

Query: 1159 XXXXXXXXXXXXXXXXIHFKVETRPEKLWVGPGSRAAKEKQYFDSHLAPFYRIEQILLAS 980
                            + FKVET+PEKLWV PGSRAA EK YFDSHLAPFYRIEQ++LA+
Sbjct: 362  VLCVSLLIPLLLCIGLLRFKVETQPEKLWVSPGSRAADEKNYFDSHLAPFYRIEQLVLAT 421

Query: 979  VSPSVGERPPSIVTEQNLKLLFEIQKKVDNLHANYSGSMVSLSDICLKPLGNDCATQSVL 800
             S S G   PSIV + N+KLLF+IQKKVD+L A+YSGS V+L+DICLKPL  DCATQSVL
Sbjct: 422  -SASSGSAAPSIVNDNNMKLLFQIQKKVDDLRASYSGSTVALADICLKPLSTDCATQSVL 480

Query: 799  QYFQMDLQNYDTYGGLTHAEYCFEHFSSDQTCLSAFTAPLDPSTALGGFSGNNYSEASAF 620
            QYFQ+D + YD   G+ HA++CF+H++S++TCLS F +P+DPST LGGFSGNN++EASAF
Sbjct: 481  QYFQLDPKKYDD-SGIDHAKFCFQHYTSEETCLSTFQSPIDPSTILGGFSGNNFTEASAF 539

Query: 619  VITYPVNNVLDETSIEFRNAVAWEKAFIQLIKDEIVPMVQAQNLTLAFSSESSIQEELKR 440
            VITYPVNN ++ T  E   AVAWE+AFI L+K+EI+PMV AQNLTL+FSSESSIQ+EL R
Sbjct: 540  VITYPVNNKVETTGQENGKAVAWERAFINLVKEEILPMVLAQNLTLSFSSESSIQDELNR 599

Query: 439  ESTADVITILVSYLVMFAYISITLGEK-HQLSSIFXXXXXXXXXXXXXXXXXXXXXSIGF 263
            ESTAD ITI++SY+VMFAYIS TLG++  +  S+F                     S+GF
Sbjct: 600  ESTADAITIVISYIVMFAYISFTLGDRPSRWLSLFVSSKVLLGLSGVVLVMLSVLGSMGF 659

Query: 262  YSSIGVKSTLIIMEVIPFLVLAVGVDNMCILVHAINRQPLELLLEERISNALTEVGPSIT 83
            +S+IGVKSTLIIMEVIPFLVLAVGVDNMCILVHA+ RQP +  LEERIS AL EVGPSIT
Sbjct: 660  FSAIGVKSTLIIMEVIPFLVLAVGVDNMCILVHAVKRQPDQSNLEERISEALVEVGPSIT 719

Query: 82   LASLSEVLAFAVGSFIPMPACRVFSMF 2
            LAS +EVLAFAV +  PMPA RVFSMF
Sbjct: 720  LASFAEVLAFAVSAINPMPATRVFSMF 746


>ref|XP_002510680.1| hedgehog receptor, putative [Ricinus communis]
            gi|223551381|gb|EEF52867.1| hedgehog receptor, putative
            [Ricinus communis]
          Length = 1235

 Score =  917 bits (2369), Expect = 0.0
 Identities = 456/724 (62%), Positives = 553/724 (76%), Gaps = 11/724 (1%)
 Frame = -1

Query: 2140 MYGICGQRSDGKALNCPNYTRSIKPDELLSSKIQSLCPTITGNVCCTAEQFETLREQVQQ 1961
            MY ICG R DGK LNCP  + S+KPDELLS KIQSLCPTITGNVCCTA QF TLR QVQQ
Sbjct: 1    MYDICGARDDGKVLNCPRGSPSVKPDELLSQKIQSLCPTITGNVCCTAAQFATLRSQVQQ 60

Query: 1960 AVPLLVGCPACLRNFLNLFCELSCSPDQSLFINVTSAKQVNGSMTVDSIDFFVTHQFGEQ 1781
            A+P LVGCPACLRNFLNLFCEL+CSP QSLFINVTS  +V  ++TVD IDF++T  FGE 
Sbjct: 61   AIPFLVGCPACLRNFLNLFCELTCSPHQSLFINVTSISKVKNNLTVDGIDFYITDAFGEG 120

Query: 1780 LFNSCKDVKFGTMNTRSMDFVGAGAQNYSEWFTFLGRQANLNEPGSPYPITFTSYISGLS 1601
            L++SCKDVKFGTMNTR+++F+GAGAQN+ EWFTF+GR+A  N PGSPY ITF S     S
Sbjct: 121  LYDSCKDVKFGTMNTRALNFIGAGAQNFREWFTFIGRRAAPNLPGSPYAITFKSAAPASS 180

Query: 1600 GIKPMNATTYSCGDSSMGFSCGDCPSSAVCIDSLSPAPHVKQSCSIKLISLKVKCLDFSL 1421
            G+KPMN +TYSCGD S+G SCGDCP++ +C ++   + H + SCS++  SLK KC+DF+L
Sbjct: 181  GMKPMNVSTYSCGDVSLGCSCGDCPTAPICANTAPHSQHERASCSVRFGSLKAKCIDFAL 240

Query: 1420 VIIYLFIVCAFLVWNFVYIKKKEGPFRT-KPLLNVKGESSNDKQETH--VSQTTAMVPSG 1250
             I+Y+ +V   L W   + K++     T KPL NV      D  E H  + +    +P  
Sbjct: 241  TILYILLVSMLLGWGLFHRKRERDQTSTMKPLPNVM-----DGGEIHSVIRRKDENLPMQ 295

Query: 1249 LKAHDP--------SVIQLYMSNFFRKYGTFVSKNPTXXXXXXXXXXXXXXXXXIHFKVE 1094
            +  + P        S++Q YM+ F+R+YGT+V+++P                  I FKVE
Sbjct: 296  MGEYSPQTGNRVQLSIVQGYMAKFYRRYGTWVARHPILVLSVSVALVLLLCLGLIRFKVE 355

Query: 1093 TRPEKLWVGPGSRAAKEKQYFDSHLAPFYRIEQILLASVSPSVGERPPSIVTEQNLKLLF 914
            TRPEKLWVGPGSRAA+EK++FDSHLAPFYRIEQ+++A+   +   + P+IVTE N+KLLF
Sbjct: 356  TRPEKLWVGPGSRAAEEKRFFDSHLAPFYRIEQLIIATTPKAEDGKLPNIVTENNIKLLF 415

Query: 913  EIQKKVDNLHANYSGSMVSLSDICLKPLGNDCATQSVLQYFQMDLQNYDTYGGLTHAEYC 734
            E+QKKVD + ANYSGSM++L+DIC+KPL  DCATQSVLQYFQMD QNY+  GG+ H  YC
Sbjct: 416  ELQKKVDGIRANYSGSMIALNDICMKPLDQDCATQSVLQYFQMDPQNYENSGGVDHINYC 475

Query: 733  FEHFSSDQTCLSAFTAPLDPSTALGGFSGNNYSEASAFVITYPVNNVLDETSIEFRNAVA 554
            F+H++S  TC+SAF APLDPSTALGGFSG+NYSEASAF++TYPVNN +D+   E + AVA
Sbjct: 476  FQHYTSADTCMSAFKAPLDPSTALGGFSGSNYSEASAFIVTYPVNNAIDKEGNETKKAVA 535

Query: 553  WEKAFIQLIKDEIVPMVQAQNLTLAFSSESSIQEELKRESTADVITILVSYLVMFAYISI 374
            WEKAFIQL+KDE++PMVQA+NLTL+FSSESSI+EELKRESTAD ITIL+SYLVMFAYIS+
Sbjct: 536  WEKAFIQLVKDELLPMVQAKNLTLSFSSESSIEEELKRESTADAITILISYLVMFAYISL 595

Query: 373  TLGEKHQLSSIFXXXXXXXXXXXXXXXXXXXXXSIGFYSSIGVKSTLIIMEVIPFLVLAV 194
            TLG+  + S  +                     S+GF+S++GVKSTLIIMEVIPFLVLAV
Sbjct: 596  TLGDTPRFSFFYFSSKVLLGLSGVMLVVLSVLGSVGFFSAVGVKSTLIIMEVIPFLVLAV 655

Query: 193  GVDNMCILVHAINRQPLELLLEERISNALTEVGPSITLASLSEVLAFAVGSFIPMPACRV 14
            GVDNMCILVHA+ RQPLEL LE RISNAL EVGPSITLASLSEVLAFAVGSFIPMPACRV
Sbjct: 656  GVDNMCILVHAVKRQPLELPLEGRISNALVEVGPSITLASLSEVLAFAVGSFIPMPACRV 715

Query: 13   FSMF 2
            FSMF
Sbjct: 716  FSMF 719


>ref|XP_006486599.1| PREDICTED: niemann-Pick C1 protein-like [Citrus sinensis]
          Length = 1287

 Score =  915 bits (2366), Expect = 0.0
 Identities = 454/726 (62%), Positives = 556/726 (76%), Gaps = 2/726 (0%)
 Frame = -1

Query: 2173 AQERYAKGYCSMYGICGQRSDGKALNCPNYTRSIKPDELLSSKIQSLCPTITGNVCCTAE 1994
            + ER++K YC+MY ICG+RSDGK LNCP  + S+KPDEL S+KI+SLCP+I+GNVCCT  
Sbjct: 38   SSERHSKEYCAMYDICGERSDGKVLNCPYGSPSVKPDELFSAKIESLCPSISGNVCCTET 97

Query: 1993 QFETLREQVQQAVPLLVGCPACLRNFLNLFCELSCSPDQSLFINVTSAKQVNGSMTVDSI 1814
            QFETLR QVQQA+P LVGCPACLRNFLNLFCELSCSP+QS FINVTS  +VNG++TVD I
Sbjct: 98   QFETLRAQVQQAIPFLVGCPACLRNFLNLFCELSCSPNQSQFINVTSVSEVNGNLTVDGI 157

Query: 1813 DFFVTHQFGEQLFNSCKDVKFGTMNTRSMDFVGAGAQNYSEWFTFLGRQANLNEPGSPYP 1634
            D++VT  FGE+L+NSCKDVKFGTMNTR++DF+GAGA+++ EWF F+G++A    PGSPY 
Sbjct: 158  DYYVTSTFGEELYNSCKDVKFGTMNTRAIDFIGAGAKSFKEWFAFIGQKAPPGFPGSPYA 217

Query: 1633 ITFTSYISGLSGIKPMNATTYSCGDSSMGFSCGDCPSSAVCIDSLSPAPHVKQSCSIKLI 1454
            I F   I   SG++ MN +TYSCGD+S+G SCGDCP S +C  S  P+P  K++C+I++ 
Sbjct: 218  INFKLSIPESSGLELMNVSTYSCGDTSLGCSCGDCPLSPMCSSSEPPSPPRKEACTIRIG 277

Query: 1453 SLKVKCLDFSLVIIYLFIVCAFLVWNFVYIKKKEG--PFRTKPLLNVKGESSNDKQETHV 1280
            SLKVKC++ SLVI Y+ ++  F  W      ++    P   +PL+    +S  D      
Sbjct: 278  SLKVKCVELSLVIAYVVLISTFFGWALFQRTRERRIPPSSVEPLIKSTSDSGPDSGIMEE 337

Query: 1279 SQTTAMVPSGLKAHDPSVIQLYMSNFFRKYGTFVSKNPTXXXXXXXXXXXXXXXXXIHFK 1100
                 ++P+  +    SV+Q YM +F+R YG +V+ NP                  I FK
Sbjct: 338  VNARDLLPT--EGGGLSVVQGYMLSFYRTYGRWVAANPAFVLCMSLAIGFVLCLGVIRFK 395

Query: 1099 VETRPEKLWVGPGSRAAKEKQYFDSHLAPFYRIEQILLASVSPSVGERPPSIVTEQNLKL 920
            VETRPEKLWVGPGSRAA EKQ+FDSHLAPFYRIEQ++LA++      + PSI+TE N +L
Sbjct: 396  VETRPEKLWVGPGSRAAGEKQFFDSHLAPFYRIEQLILATLPDPKNGKQPSIITEDNFQL 455

Query: 919  LFEIQKKVDNLHANYSGSMVSLSDICLKPLGNDCATQSVLQYFQMDLQNYDTYGGLTHAE 740
            LFE+QKKVD + AN S S+VS++DICLKPLG DCA+QSVLQYF+MD +NYD+YGG+ HAE
Sbjct: 456  LFEMQKKVDGVRANDSASLVSITDICLKPLGEDCASQSVLQYFKMDPENYDSYGGIEHAE 515

Query: 739  YCFEHFSSDQTCLSAFTAPLDPSTALGGFSGNNYSEASAFVITYPVNNVLDETSIEFRNA 560
            YCF+H++S  TCLSAF APLDPST LGGFSGNNYSEASAF+ITYPVNN +DETS E R A
Sbjct: 516  YCFQHYASSDTCLSAFKAPLDPSTVLGGFSGNNYSEASAFIITYPVNNAIDETSKENRKA 575

Query: 559  VAWEKAFIQLIKDEIVPMVQAQNLTLAFSSESSIQEELKRESTADVITILVSYLVMFAYI 380
            VAWEKAFIQL K+E++PMVQ+ NLTL+FSSESS++EELKRESTADV+TI+ SYLVMFAYI
Sbjct: 576  VAWEKAFIQLAKEELLPMVQSSNLTLSFSSESSLEEELKRESTADVVTIVASYLVMFAYI 635

Query: 379  SITLGEKHQLSSIFXXXXXXXXXXXXXXXXXXXXXSIGFYSSIGVKSTLIIMEVIPFLVL 200
            S+ LG+  + SS +                     S+GF+S+IGVKSTLIIMEVIPFLVL
Sbjct: 636  SVALGDTPRFSSFYVSSKVLLGLSGVILVMLSVLGSVGFFSAIGVKSTLIIMEVIPFLVL 695

Query: 199  AVGVDNMCILVHAINRQPLELLLEERISNALTEVGPSITLASLSEVLAFAVGSFIPMPAC 20
            AVGVDNMCILV+A+ RQP EL+LE RISNAL EVGPSITLASLSE LAFAVGSFIPMPAC
Sbjct: 696  AVGVDNMCILVNAVKRQPTELVLETRISNALVEVGPSITLASLSEFLAFAVGSFIPMPAC 755

Query: 19   RVFSMF 2
            RVFSMF
Sbjct: 756  RVFSMF 761


>ref|XP_006383769.1| hypothetical protein POPTR_0005s27320g [Populus trichocarpa]
            gi|550339845|gb|ERP61566.1| hypothetical protein
            POPTR_0005s27320g [Populus trichocarpa]
          Length = 1228

 Score =  914 bits (2363), Expect = 0.0
 Identities = 454/716 (63%), Positives = 547/716 (76%), Gaps = 3/716 (0%)
 Frame = -1

Query: 2140 MYGICGQRSDGKALNCPNYTRSIKPDELLSSKIQSLCPTITGNVCCTAEQFETLREQVQQ 1961
            MY ICG R DGK LNCP  + S+KPD+LLS KIQSLCPTITGNVCC+  QF+TLR QVQQ
Sbjct: 1    MYDICGAREDGKVLNCPYGSPSVKPDDLLSQKIQSLCPTITGNVCCSEAQFDTLRSQVQQ 60

Query: 1960 AVPLLVGCPACLRNFLNLFCELSCSPDQSLFINVTSAKQVNGSMTVDSIDFFVTHQFGEQ 1781
            A+P LVGCPACLRNFLNLFCEL+CSP QS FINVT+  +V G++TV  IDF+ +  FGE 
Sbjct: 61   AIPFLVGCPACLRNFLNLFCELTCSPHQSTFINVTTTAKVKGNLTVSGIDFYASDAFGEG 120

Query: 1780 LFNSCKDVKFGTMNTRSMDFVGAGAQNYSEWFTFLGRQANLNEPGSPYPITFTSYISGLS 1601
            L+ SCKDVKFGTMNTR+++F+GAGAQN++EW+ F+GR+A L+ PGSPY +TF       S
Sbjct: 121  LYESCKDVKFGTMNTRALNFIGAGAQNFTEWYAFIGRRAPLDVPGSPYAMTFKPTAPESS 180

Query: 1600 GIKPMNATTYSCGDSSMGFSCGDCPSSAVCIDSLSPAPHVKQSCSIKLISLKVKCLDFSL 1421
            GIKPMN +TYSCGD S+G SCGDCP S VC ++  P  H   SC++++ SLK KC+DF+L
Sbjct: 181  GIKPMNVSTYSCGDISLGCSCGDCPQSPVCANTAPPPHHEGGSCAVRIGSLKAKCVDFAL 240

Query: 1420 VIIYLFIVCAFLVWNFVYIKKKEGPF-RTKPLLNVK--GESSNDKQETHVSQTTAMVPSG 1250
             I+Y+ ++  FL W   + K++     R  PL ++K  GE    K E   +Q     P  
Sbjct: 241  TILYIILISMFLGWGLFHRKRERNQTSRMNPLSDIKDSGEVIRKKDENLPAQMVEDSPQT 300

Query: 1249 LKAHDPSVIQLYMSNFFRKYGTFVSKNPTXXXXXXXXXXXXXXXXXIHFKVETRPEKLWV 1070
                  S++Q YMS F+R+YGT+V++NP                  I FKVETRPEKLWV
Sbjct: 301  GSRVQLSIVQGYMSKFYRRYGTWVARNPILVLSLSLAVILLLCVGLIRFKVETRPEKLWV 360

Query: 1069 GPGSRAAKEKQYFDSHLAPFYRIEQILLASVSPSVGERPPSIVTEQNLKLLFEIQKKVDN 890
            GPGS+ A+EK++FD+HLAPFYRIEQ++LA+V  +  ++ PSIVTE N+KLLFEIQKKVD 
Sbjct: 361  GPGSKVAEEKRFFDTHLAPFYRIEQLILATVPDAGAQKLPSIVTEDNIKLLFEIQKKVDG 420

Query: 889  LHANYSGSMVSLSDICLKPLGNDCATQSVLQYFQMDLQNYDTYGGLTHAEYCFEHFSSDQ 710
            + ANYSGSMVSL+DIC+KPL  DCATQSVLQYFQMD QN + YGG+ H  YC +H++S  
Sbjct: 421  IRANYSGSMVSLTDICMKPLDKDCATQSVLQYFQMDPQNLENYGGVEHVNYCLQHYTSAD 480

Query: 709  TCLSAFTAPLDPSTALGGFSGNNYSEASAFVITYPVNNVLDETSIEFRNAVAWEKAFIQL 530
            TC SAF APLDPST+LGGFSGNNYSEASAF++TYPVNNV+D+   E   AVAWEKAFIQL
Sbjct: 481  TCRSAFKAPLDPSTSLGGFSGNNYSEASAFIVTYPVNNVIDKEGNETDKAVAWEKAFIQL 540

Query: 529  IKDEIVPMVQAQNLTLAFSSESSIQEELKRESTADVITILVSYLVMFAYISITLGEKHQL 350
            +K+E++PMVQ++NLTL+FSSESSI+EELKRESTADVITIL+SYLVMFAYIS+TLG+   L
Sbjct: 541  VKNELLPMVQSKNLTLSFSSESSIEEELKRESTADVITILISYLVMFAYISLTLGDAPHL 600

Query: 349  SSIFXXXXXXXXXXXXXXXXXXXXXSIGFYSSIGVKSTLIIMEVIPFLVLAVGVDNMCIL 170
            SS +                     S+GF+S+IGVKSTLIIMEVIPFLVLAVGVDNMCIL
Sbjct: 601  SSFYISSKVLLGLSGVMLVMLSVLGSVGFFSAIGVKSTLIIMEVIPFLVLAVGVDNMCIL 660

Query: 169  VHAINRQPLELLLEERISNALTEVGPSITLASLSEVLAFAVGSFIPMPACRVFSMF 2
            VHA+ RQPLEL LE RISNAL EVGPSITLASLSEVLAFA GSFIPMPACRVFSMF
Sbjct: 661  VHAVKRQPLELPLEGRISNALVEVGPSITLASLSEVLAFAAGSFIPMPACRVFSMF 716


>gb|EXC31541.1| Niemann-Pick C1 protein [Morus notabilis]
          Length = 1294

 Score =  914 bits (2362), Expect = 0.0
 Identities = 467/763 (61%), Positives = 575/763 (75%), Gaps = 23/763 (3%)
 Frame = -1

Query: 2221 IQVTLIFFSGNFQPSYAQERYAKGYCSMYGICGQRSDGKALNCPNYTRSIKPDELLSSKI 2042
            +QV  I    + + S+A E++ + YC+MY ICG+RSDGK LNCP  + S+KPDEL S+KI
Sbjct: 14   LQVIFIASLLSAEKSFASEKHHEEYCAMYDICGERSDGKVLNCPYGSSSVKPDELFSAKI 73

Query: 2041 QSLCPTITGNVCCTAEQFETLREQVQQAVPLLVGCPACLRNFLNLFCELSCSPDQSLFIN 1862
            QSLCP+I+GNVCCT  QF+TLR QVQQA+P LVGCPACLRNFLNLFCELSCSP+QS FIN
Sbjct: 74   QSLCPSISGNVCCTETQFDTLRGQVQQAIPFLVGCPACLRNFLNLFCELSCSPNQSKFIN 133

Query: 1861 VTSAKQV----------------NGSMTVDSIDFFVTHQFGEQLFNSCKDVKFGTMNTRS 1730
            VTS  +V                NG++TVDSID++V+  FGE L++SCKDVKFGTMNTR+
Sbjct: 134  VTSTSEVRHTSSAIYFYGDPVPVNGNLTVDSIDYYVSDNFGEALYDSCKDVKFGTMNTRA 193

Query: 1729 MDFVGAGAQNYSEWFTFLGRQANLNEPGSPYPITFTSYISGLSGIKPMNATTYSCGDSSM 1550
            ++F+GAGA+N+ EWF F+G +A    PGSPY I F S +S  SG++PMN + YSC D+S+
Sbjct: 194  IEFIGAGAKNFKEWFAFIGAKAAPGIPGSPYSINFKSNVSESSGMEPMNVSVYSCADTSL 253

Query: 1549 GFSCGDCPSSAVCIDSLSPAPHVKQSCSIKLISLKVKCLDFSLVIIYLFIVCAFLVWN-F 1373
            G SCGDCP S  C  S  PAP ++++CSI++ SLKV+C++ S+ I+Y+  V AFL W  F
Sbjct: 254  GCSCGDCPLSTSCSSSEPPAPSIEEACSIRIGSLKVRCIELSVAILYILFVSAFLGWGVF 313

Query: 1372 VYIKKKEGPFR-TKPLLNV-KGESSNDKQETHVSQTTA---MVPSGLKAHDPSVIQLYMS 1208
               +++  P    +PLLNV   E  + K + + S T     M P        S IQ Y+S
Sbjct: 314  RRTRERRTPSSGMEPLLNVLHDELDSVKMQNNESNTAVVDGMFPQVTNKVQLSTIQGYVS 373

Query: 1207 NFFRKYGTFVSKNPTXXXXXXXXXXXXXXXXXIHFKVETRPEKLWVGPGSRAAKEKQYFD 1028
            +FFR YGT+V++NPT                   FKVETRPEKLWVG GSRAA+EK++FD
Sbjct: 374  SFFRVYGTWVARNPTLVLCSSLAIVLIFCIGLARFKVETRPEKLWVGHGSRAAEEKEFFD 433

Query: 1027 SHLAPFYRIEQILLASVS-PSVGERPPSIVTEQNLKLLFEIQKKVDNLHANYSGSMVSLS 851
            + LAPFYRIEQ+++A++S P +G+R PSIVTE N++LLF+IQ KVD + ANYSGSMVSL+
Sbjct: 434  NRLAPFYRIEQLIIATISDPHLGKR-PSIVTEDNIQLLFDIQMKVDGIRANYSGSMVSLT 492

Query: 850  DICLKPLGNDCATQSVLQYFQMDLQNYDTYGGLTHAEYCFEHFSSDQTCLSAFTAPLDPS 671
            DICLKPLG DCATQS+LQY++MD +NYDTYGG+ HAEYCF+H++S  TCLSAF APLDPS
Sbjct: 493  DICLKPLGQDCATQSILQYYKMDPENYDTYGGVEHAEYCFQHYTSADTCLSAFKAPLDPS 552

Query: 670  TALGGFSGNNYSEASAFVITYPVNNVLDETSIEFRNAVAWEKAFIQLIKDEIVPMVQAQN 491
            TALGGF GNNYSEASAFV+TYPVNN +DE       A+AWEKAFI+L K+E++ +VQ+ N
Sbjct: 553  TALGGFPGNNYSEASAFVVTYPVNNAVDELGDGNGRALAWEKAFIKLAKEELLSLVQSSN 612

Query: 490  LTLAFSSESSIQEELKRESTADVITILVSYLVMFAYISITLGEKHQLSSIFXXXXXXXXX 311
            LTL+FSSESSI+EELKRESTADVITILVSYLVMFAYIS+TLG+  QLSS +         
Sbjct: 613  LTLSFSSESSIEEELKRESTADVITILVSYLVMFAYISVTLGDTPQLSSFYLSSKALLGL 672

Query: 310  XXXXXXXXXXXXSIGFYSSIGVKSTLIIMEVIPFLVLAVGVDNMCILVHAINRQPLELLL 131
                        S+G +S++GVKSTLIIMEVIPFLVLAVGVDNMCILVHA+ RQP+EL L
Sbjct: 673  SGVVLVMLSVLGSVGLFSALGVKSTLIIMEVIPFLVLAVGVDNMCILVHAVKRQPVELPL 732

Query: 130  EERISNALTEVGPSITLASLSEVLAFAVGSFIPMPACRVFSMF 2
            E+RISNAL EVGPSITLASLSEVLAFAVGS IPMPACRVFSMF
Sbjct: 733  EQRISNALVEVGPSITLASLSEVLAFAVGSIIPMPACRVFSMF 775


>gb|EOX97440.1| Hedgehog receptor, putative isoform 4 [Theobroma cacao]
          Length = 1121

 Score =  914 bits (2361), Expect = 0.0
 Identities = 459/740 (62%), Positives = 557/740 (75%), Gaps = 8/740 (1%)
 Frame = -1

Query: 2197 SGNFQPSY--AQERYAKGYCSMYGICGQRSDGKALNCPNYTRSIKPDELLSSKIQSLCPT 2024
            SG    SY  A ER++K YC+MY ICGQRSDGK LNCP  T S+KPDEL S+KIQSLCP+
Sbjct: 30   SGGLSVSYLAAGERHSKEYCAMYDICGQRSDGKVLNCPYGTPSVKPDELFSAKIQSLCPS 89

Query: 2023 ITGNVCCTAEQFETLREQVQQAVPLLVGCPACLRNFLNLFCELSCSPDQSLFINVTSAKQ 1844
            I+GNVCCT +QF+TLR QVQQA+P LVGCPACLRNFLNLFCELSCSP+QSLFINVTS  +
Sbjct: 90   ISGNVCCTEDQFDTLRAQVQQAIPFLVGCPACLRNFLNLFCELSCSPNQSLFINVTSVSE 149

Query: 1843 VNGSMTVDSIDFFVTHQFGEQLFNSCKDVKFGTMNTRSMDFVGAGAQNYSEWFTFLGRQA 1664
            VNG++TVD IDF+++  FGE L++SCK+VKFGTMNTR+++F+GAGA N+ EWF F+G++A
Sbjct: 150  VNGNLTVDGIDFYISDAFGEGLYDSCKEVKFGTMNTRAIEFIGAGATNFKEWFEFIGQKA 209

Query: 1663 NLNEPGSPYPITFTSYISGLSGIKPMNATTYSCGDSSMGFSCGDCPSSAVCIDSLSPAPH 1484
                PGSPY I F S +  LSG++ MN + YSCGD+S+G SCGDCPSS  C +S  P+P 
Sbjct: 210  PPGFPGSPYAIDFKSSVPDLSGMELMNVSAYSCGDTSLGCSCGDCPSSPQCSNSEPPSPP 269

Query: 1483 VKQSCSIKLISLKVKCLDFSLVIIYLFIVCAFLVWNFVYIKKKEGPFRTK-PLLNVKGES 1307
             K  CSI +  +KVKC++F+L I Y+ +V   L W   +  ++      + PLL    E 
Sbjct: 270  KKDQCSIDIGPVKVKCIEFALAIAYIVLVFGLLGWALFHRPRERRDVSDREPLLKSMDEG 329

Query: 1306 SNDKQETHVSQTTAMVPSGLKAH-----DPSVIQLYMSNFFRKYGTFVSKNPTXXXXXXX 1142
              +  E       A+    +          SVIQ YMS F+R YG +V++NPT       
Sbjct: 330  EVNSAEMQHDDNLALKGREVALQLTNGAQLSVIQGYMSRFYRSYGAWVTRNPTLVLCSSL 389

Query: 1141 XXXXXXXXXXIHFKVETRPEKLWVGPGSRAAKEKQYFDSHLAPFYRIEQILLASVSPSVG 962
                      I F+VETRPEKLWVG GS+AA+EKQ+FDSHLAPFYRIEQ++LA++     
Sbjct: 390  AVVIVLCFGLIRFEVETRPEKLWVGHGSKAAEEKQFFDSHLAPFYRIEQLILATLPDKTH 449

Query: 961  ERPPSIVTEQNLKLLFEIQKKVDNLHANYSGSMVSLSDICLKPLGNDCATQSVLQYFQMD 782
             + PSIVTE N++LLFEIQ+KVD + ANYSGS VSL+DICL PLG  CATQSVLQYF+MD
Sbjct: 450  GKLPSIVTEDNIQLLFEIQEKVDRIRANYSGSTVSLTDICLNPLGQACATQSVLQYFKMD 509

Query: 781  LQNYDTYGGLTHAEYCFEHFSSDQTCLSAFTAPLDPSTALGGFSGNNYSEASAFVITYPV 602
             +NYD YGG+THAEYCF+H++S  +CLSAF APLDPSTALGGFSGNNYSEASAFV+TYPV
Sbjct: 510  RENYDYYGGVTHAEYCFQHYTSSDSCLSAFEAPLDPSTALGGFSGNNYSEASAFVVTYPV 569

Query: 601  NNVLDETSIEFRNAVAWEKAFIQLIKDEIVPMVQAQNLTLAFSSESSIQEELKRESTADV 422
            NN +DE       AVAWEKAFIQL+K+E++PMVQ++NLTL+FSSESSI+EELKRESTAD+
Sbjct: 570  NNAIDEAGNGNGKAVAWEKAFIQLVKEELLPMVQSRNLTLSFSSESSIEEELKRESTADI 629

Query: 421  ITILVSYLVMFAYISITLGEKHQLSSIFXXXXXXXXXXXXXXXXXXXXXSIGFYSSIGVK 242
            +TI+VSYLVMF YIS+TLG+   LS+ +                     S+G +S+ GVK
Sbjct: 630  VTIVVSYLVMFVYISVTLGDAPHLSTFYISSKVLLGLSGVILVMLSVLGSVGVFSAFGVK 689

Query: 241  STLIIMEVIPFLVLAVGVDNMCILVHAINRQPLELLLEERISNALTEVGPSITLASLSEV 62
            STLIIMEVIPFLVLAVGVDNMCILVHA+ RQPLEL LEERISNAL EVGPSITLASLSE+
Sbjct: 690  STLIIMEVIPFLVLAVGVDNMCILVHAVKRQPLELPLEERISNALVEVGPSITLASLSEI 749

Query: 61   LAFAVGSFIPMPACRVFSMF 2
            LAFAVG FIPMPACRVFS+F
Sbjct: 750  LAFAVGGFIPMPACRVFSLF 769


>gb|EOX97439.1| Hedgehog receptor, putative isoform 3 [Theobroma cacao]
          Length = 1287

 Score =  914 bits (2361), Expect = 0.0
 Identities = 459/740 (62%), Positives = 557/740 (75%), Gaps = 8/740 (1%)
 Frame = -1

Query: 2197 SGNFQPSY--AQERYAKGYCSMYGICGQRSDGKALNCPNYTRSIKPDELLSSKIQSLCPT 2024
            SG    SY  A ER++K YC+MY ICGQRSDGK LNCP  T S+KPDEL S+KIQSLCP+
Sbjct: 75   SGGLSVSYLAAGERHSKEYCAMYDICGQRSDGKVLNCPYGTPSVKPDELFSAKIQSLCPS 134

Query: 2023 ITGNVCCTAEQFETLREQVQQAVPLLVGCPACLRNFLNLFCELSCSPDQSLFINVTSAKQ 1844
            I+GNVCCT +QF+TLR QVQQA+P LVGCPACLRNFLNLFCELSCSP+QSLFINVTS  +
Sbjct: 135  ISGNVCCTEDQFDTLRAQVQQAIPFLVGCPACLRNFLNLFCELSCSPNQSLFINVTSVSE 194

Query: 1843 VNGSMTVDSIDFFVTHQFGEQLFNSCKDVKFGTMNTRSMDFVGAGAQNYSEWFTFLGRQA 1664
            VNG++TVD IDF+++  FGE L++SCK+VKFGTMNTR+++F+GAGA N+ EWF F+G++A
Sbjct: 195  VNGNLTVDGIDFYISDAFGEGLYDSCKEVKFGTMNTRAIEFIGAGATNFKEWFEFIGQKA 254

Query: 1663 NLNEPGSPYPITFTSYISGLSGIKPMNATTYSCGDSSMGFSCGDCPSSAVCIDSLSPAPH 1484
                PGSPY I F S +  LSG++ MN + YSCGD+S+G SCGDCPSS  C +S  P+P 
Sbjct: 255  PPGFPGSPYAIDFKSSVPDLSGMELMNVSAYSCGDTSLGCSCGDCPSSPQCSNSEPPSPP 314

Query: 1483 VKQSCSIKLISLKVKCLDFSLVIIYLFIVCAFLVWNFVYIKKKEGPFRTK-PLLNVKGES 1307
             K  CSI +  +KVKC++F+L I Y+ +V   L W   +  ++      + PLL    E 
Sbjct: 315  KKDQCSIDIGPVKVKCIEFALAIAYIVLVFGLLGWALFHRPRERRDVSDREPLLKSMDEG 374

Query: 1306 SNDKQETHVSQTTAMVPSGLKAH-----DPSVIQLYMSNFFRKYGTFVSKNPTXXXXXXX 1142
              +  E       A+    +          SVIQ YMS F+R YG +V++NPT       
Sbjct: 375  EVNSAEMQHDDNLALKGREVALQLTNGAQLSVIQGYMSRFYRSYGAWVTRNPTLVLCSSL 434

Query: 1141 XXXXXXXXXXIHFKVETRPEKLWVGPGSRAAKEKQYFDSHLAPFYRIEQILLASVSPSVG 962
                      I F+VETRPEKLWVG GS+AA+EKQ+FDSHLAPFYRIEQ++LA++     
Sbjct: 435  AVVIVLCFGLIRFEVETRPEKLWVGHGSKAAEEKQFFDSHLAPFYRIEQLILATLPDKTH 494

Query: 961  ERPPSIVTEQNLKLLFEIQKKVDNLHANYSGSMVSLSDICLKPLGNDCATQSVLQYFQMD 782
             + PSIVTE N++LLFEIQ+KVD + ANYSGS VSL+DICL PLG  CATQSVLQYF+MD
Sbjct: 495  GKLPSIVTEDNIQLLFEIQEKVDRIRANYSGSTVSLTDICLNPLGQACATQSVLQYFKMD 554

Query: 781  LQNYDTYGGLTHAEYCFEHFSSDQTCLSAFTAPLDPSTALGGFSGNNYSEASAFVITYPV 602
             +NYD YGG+THAEYCF+H++S  +CLSAF APLDPSTALGGFSGNNYSEASAFV+TYPV
Sbjct: 555  RENYDYYGGVTHAEYCFQHYTSSDSCLSAFEAPLDPSTALGGFSGNNYSEASAFVVTYPV 614

Query: 601  NNVLDETSIEFRNAVAWEKAFIQLIKDEIVPMVQAQNLTLAFSSESSIQEELKRESTADV 422
            NN +DE       AVAWEKAFIQL+K+E++PMVQ++NLTL+FSSESSI+EELKRESTAD+
Sbjct: 615  NNAIDEAGNGNGKAVAWEKAFIQLVKEELLPMVQSRNLTLSFSSESSIEEELKRESTADI 674

Query: 421  ITILVSYLVMFAYISITLGEKHQLSSIFXXXXXXXXXXXXXXXXXXXXXSIGFYSSIGVK 242
            +TI+VSYLVMF YIS+TLG+   LS+ +                     S+G +S+ GVK
Sbjct: 675  VTIVVSYLVMFVYISVTLGDAPHLSTFYISSKVLLGLSGVILVMLSVLGSVGVFSAFGVK 734

Query: 241  STLIIMEVIPFLVLAVGVDNMCILVHAINRQPLELLLEERISNALTEVGPSITLASLSEV 62
            STLIIMEVIPFLVLAVGVDNMCILVHA+ RQPLEL LEERISNAL EVGPSITLASLSE+
Sbjct: 735  STLIIMEVIPFLVLAVGVDNMCILVHAVKRQPLELPLEERISNALVEVGPSITLASLSEI 794

Query: 61   LAFAVGSFIPMPACRVFSMF 2
            LAFAVG FIPMPACRVFS+F
Sbjct: 795  LAFAVGGFIPMPACRVFSLF 814