BLASTX 2.2.25 [Feb-01-2011]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= Sinomenium21_contig00030714
         (1050 letters)

Database: ./nr 
           38,876,450 sequences; 13,856,398,315 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gb|ACO90232.1| putative norcoclaurine 6-O-methyltransferase [Pap...   250   6e-64
sp|Q6WUC1.1|6OMT_PAPSO RecName: Full=(RS)-norcoclaurine 6-O-meth...   249   1e-63
gb|AAP45315.1| S-adenosyl-L-methionine:norcoclaurine 6-O-methylt...   247   7e-63
dbj|BAM37634.1| O-methyltransferase [Eschscholzia californica]        244   3e-62
gb|AAU20765.1| (S)-norcoclaurine 6-O-methyltransferase [Thalictr...   240   8e-61
sp|Q9LEL6.1|6OMT_COPJA RecName: Full=(RS)-norcoclaurine 6-O-meth...   234   3e-59
gb|ACO90250.1| norcoclaurine 6-O-methyltransferase-like protein ...   234   4e-59
gb|ACO90225.1| putative norcoclaurine 6-O-methyltransferase [Pap...   230   6e-58
gb|AFB74613.1| O-methyltransferase 3 [Papaver somniferum] gi|388...   221   5e-55
sp|Q8H9A8.1|COOMT_COPJA RecName: Full=Columbamine O-methyltransf...   219   1e-54
sp|Q9LEL5.1|4OMT_COPJA RecName: Full=3'-hydroxy-N-methyl-(S)-coc...   219   2e-54
gb|AAU20768.1| 3'-hydroxy-N-methyl-(S)-coclaurine 4'-O-methyltra...   218   3e-54
gb|ABY75613.1| S-adenosyl-L-methionine:3'-hydroxy-N-methylcoclau...   218   3e-54
ref|XP_006858228.1| hypothetical protein AMTR_s00062p00190100 [A...   216   1e-53
gb|ACN88562.1| norreticuline-7-O-methyltransferase [Papaver somn...   216   1e-53
ref|XP_002278127.1| PREDICTED: isoflavone-7-O-methyltransferase ...   213   8e-53
ref|XP_006368013.1| PREDICTED: trans-resveratrol di-O-methyltran...   212   2e-52
emb|CAN75970.1| hypothetical protein VITISV_009881 [Vitis vinifera]   212   2e-52
sp|Q6VMW0.1|Q8OMT_MENPI RecName: Full=8-hydroxyquercetin 8-O-met...   212   2e-52
gb|AAR09603.1| O-methyltransferase [Mentha x piperita]                211   3e-52

>gb|ACO90232.1| putative norcoclaurine 6-O-methyltransferase [Papaver bracteatum]
          Length = 346

 Score =  250 bits (639), Expect = 6e-64
 Identities = 128/282 (45%), Positives = 179/282 (63%), Gaps = 4/282 (1%)
 Frame = +3

Query: 216  DMKAQAQVWRYVYGFAESLTLKCAIQLGIPDILHQHGRPMTLSELADSLPLPT-VNQDRL 392
            D + QA++W+ +YGFAESL LKCA+QL I + LH + +PM+LSELA  LP+P  VN+DRL
Sbjct: 8    DQQNQAKIWKQIYGFAESLVLKCAVQLEIAETLHNNVKPMSLSELASKLPVPQPVNEDRL 67

Query: 393  FRIMRYLVHMGLFDLVDSDKKYALNPASNLLIKGQDKSLASFALLQYYEMD---AWHHLS 563
            FRIMRYLVHM LF +  + +KY+L P +  L++G +KS+   ++L   + D    WHHL 
Sbjct: 68   FRIMRYLVHMELFKIDATTQKYSLAPPAKYLLRGWEKSMVD-SILCINDKDFLAPWHHLG 126

Query: 564  AAVEGGVTPWEKCHGVDYREYFAKDSVANQLLSDAMTSHTSMVTEALVEGCKKAKXXXXX 743
              + G    +EK  G     Y +++   NQL + AM   T +VT AL   CK        
Sbjct: 127  DGLTGNCDAFEKALGKSIWVYMSENPEKNQLFNAAMACDTRLVTSALANECKSI-FSDGI 185

Query: 744  XXXXXXXXXXXXAARAVAKAFPGIKCAVFDLPHVIATAPECAEVERIEGDMFVSVPETDV 923
                        A + ++KAFP IKC ++DLPHVIA +PE   + +I GDMF S+P  D 
Sbjct: 186  KTLVDVGGGTGTAVKTISKAFPDIKCTIYDLPHVIADSPEIPNITKISGDMFKSIPSADA 245

Query: 924  VFMKSVLHDWGDEDCVKILKKCKEAIGGRKGGKVVILDIVLD 1049
            +FMK +LHDW DE+C++ILK+CKEA+   K GKV+I+D+V+D
Sbjct: 246  IFMKCILHDWNDEECIQILKRCKEAL--PKDGKVIIVDVVID 285


>sp|Q6WUC1.1|6OMT_PAPSO RecName: Full=(RS)-norcoclaurine 6-O-methyltransferase; Short=6OMT
            gi|33286374|gb|AAQ01669.1| (R,S)-norcoclaurine
            6-O-methyltransferase [Papaver somniferum]
            gi|571330878|gb|AHF27395.1| (R,S)-norcoclaurine
            6-O-methyltransferase [synthetic construct]
          Length = 346

 Score =  249 bits (636), Expect = 1e-63
 Identities = 128/282 (45%), Positives = 179/282 (63%), Gaps = 4/282 (1%)
 Frame = +3

Query: 216  DMKAQAQVWRYVYGFAESLTLKCAIQLGIPDILHQHGRPMTLSELADSLPLPT-VNQDRL 392
            D + QA++W+ +YGFAESL LKCA+QL I + LH + +PM+LSELA  LP+   VN+DRL
Sbjct: 8    DQQNQAKIWKQIYGFAESLVLKCAVQLEIAETLHNNVKPMSLSELASKLPVAQPVNEDRL 67

Query: 393  FRIMRYLVHMGLFDLVDSDKKYALNPASNLLIKGQDKSLASFALLQYYEMD---AWHHLS 563
            FRIMRYLVHM LF +  + +KY+L P +  L++G +KS+   ++L   + D    WHHL 
Sbjct: 68   FRIMRYLVHMELFKIDATTQKYSLAPPAKYLLRGWEKSMVD-SILCINDKDFLAPWHHLG 126

Query: 564  AAVEGGVTPWEKCHGVDYREYFAKDSVANQLLSDAMTSHTSMVTEALVEGCKKAKXXXXX 743
              + G    +EK  G     Y + +   NQL + AM   T +VT AL   CK        
Sbjct: 127  DGLTGNCDAFEKALGKSIWVYMSVNPEKNQLFNAAMACDTRLVTSALANECKSI-FSDGI 185

Query: 744  XXXXXXXXXXXXAARAVAKAFPGIKCAVFDLPHVIATAPECAEVERIEGDMFVSVPETDV 923
                        A +A++KAFP IKC ++DLPHVIA +PE   + +I GDMF S+P  D 
Sbjct: 186  STLVDVGGGTGTAVKAISKAFPDIKCTIYDLPHVIADSPEIPNITKISGDMFKSIPSADA 245

Query: 924  VFMKSVLHDWGDEDCVKILKKCKEAIGGRKGGKVVILDIVLD 1049
            +FMK +LHDW D++C++ILK+CKEA+   KGGKV+I+D+V+D
Sbjct: 246  IFMKCILHDWNDDECIQILKRCKEAL--PKGGKVIIVDVVID 285


>gb|AAP45315.1| S-adenosyl-L-methionine:norcoclaurine 6-O-methyltransferase [Papaver
            somniferum]
          Length = 346

 Score =  247 bits (630), Expect = 7e-63
 Identities = 127/282 (45%), Positives = 179/282 (63%), Gaps = 4/282 (1%)
 Frame = +3

Query: 216  DMKAQAQVWRYVYGFAESLTLKCAIQLGIPDILHQHGRPMTLSELADSLPLPT-VNQDRL 392
            D + QA++W+ +YGFAESL LKCA+QL I + LH + +PM+LSELA  LP+   VN+DRL
Sbjct: 8    DQQNQAKIWKQIYGFAESLVLKCAVQLEIAETLHNNVKPMSLSELASKLPVAQPVNEDRL 67

Query: 393  FRIMRYLVHMGLFDLVDSDKKYALNPASNLLIKGQDKSLASFALLQYYEMD---AWHHLS 563
            FRIMRYLVHM LF +  + +KY+L P +  L++G +KS+   ++L   + D    WHHL 
Sbjct: 68   FRIMRYLVHMELFKIDATTQKYSLAPPAKYLLRGWEKSMVD-SILCINDKDFLAPWHHLG 126

Query: 564  AAVEGGVTPWEKCHGVDYREYFAKDSVANQLLSDAMTSHTSMVTEALVEGCKKAKXXXXX 743
              + G    +EK  G     Y +++   NQL + AM   T +VT AL   CK        
Sbjct: 127  DGLTGNCDAFEKALGKSIWVYMSENPEKNQLFNAAMACDTRLVTSALANECKSI-FSDGI 185

Query: 744  XXXXXXXXXXXXAARAVAKAFPGIKCAVFDLPHVIATAPECAEVERIEGDMFVSVPETDV 923
                        A +A++KAFP IKC ++DLPHVIA +PE   + +I GDMF S+P  D 
Sbjct: 186  STLVDVGGGTGTAVKAISKAFPDIKCTIYDLPHVIADSPEIPNITKISGDMFKSIPSADA 245

Query: 924  VFMKSVLHDWGDEDCVKILKKCKEAIGGRKGGKVVILDIVLD 1049
            +FMK +LHDW D++C++ILK+CKEA+   K GKV+I+D+V+D
Sbjct: 246  IFMKCILHDWNDDECIQILKRCKEAL--PKVGKVIIVDVVID 285


>dbj|BAM37634.1| O-methyltransferase [Eschscholzia californica]
          Length = 351

 Score =  244 bits (624), Expect = 3e-62
 Identities = 124/284 (43%), Positives = 179/284 (63%), Gaps = 6/284 (2%)
 Frame = +3

Query: 216  DMKAQAQVWRYVYGFAESLTLKCAIQLGIPDILHQHGRPMTLSELADSLPLPTVNQDRLF 395
            D   QA++W+++YGFAESL LK A++L I D +H HG+PMTLSELA  LP+  V+ DRL+
Sbjct: 10   DQATQAKIWKHIYGFAESLILKSAVELEIADTIHNHGKPMTLSELASKLPVQPVDLDRLY 69

Query: 396  RIMRYLVHMGLF----DLVDSDKKYALNPASNLLIKGQDKSLASFALLQYYE--MDAWHH 557
            R+MRYLVHM LF    D  +   KY+L P +  LIKG +KS+ S  LL   +  M  WHH
Sbjct: 70   RVMRYLVHMKLFKKQEDEDEESIKYSLLPPAKFLIKGWEKSMVSAILLINDKDFMSPWHH 129

Query: 558  LSAAVEGGVTPWEKCHGVDYREYFAKDSVANQLLSDAMTSHTSMVTEALVEGCKKAKXXX 737
            L   +      ++K  G    +Y + +   N++ ++ M   + +V+ ALV  C       
Sbjct: 130  LKEGLVNNSNAFDKALGKSIWDYMSANPDKNKVFNEGMACDSRLVSSALVNEC--GNIFQ 187

Query: 738  XXXXXXXXXXXXXXAARAVAKAFPGIKCAVFDLPHVIATAPECAEVERIEGDMFVSVPET 917
                          A +AV+KAFP IKC+++DLPHVI+ +P+   + +IEG+MF S+P  
Sbjct: 188  GIQTLVDVGGGTGTAVKAVSKAFPHIKCSIYDLPHVISDSPDIPNIVKIEGEMFKSIPSA 247

Query: 918  DVVFMKSVLHDWGDEDCVKILKKCKEAIGGRKGGKVVILDIVLD 1049
            D + MK +LHDW D++C++ILKKCKEA+  ++GGKV+I+DIVLD
Sbjct: 248  DAILMKCILHDWNDDECIEILKKCKEAV-PKEGGKVIIVDIVLD 290


>gb|AAU20765.1| (S)-norcoclaurine 6-O-methyltransferase [Thalictrum flavum subsp.
            glaucum]
          Length = 350

 Score =  240 bits (612), Expect = 8e-61
 Identities = 124/288 (43%), Positives = 181/288 (62%), Gaps = 8/288 (2%)
 Frame = +3

Query: 210  EEDMKAQAQVWRYVYGFAESLTLKCAIQLGIPDILHQHGRPMTLSELADSLPLPTVNQDR 389
            +E++ +QA++W ++YGFA+SL LK A+QL + +I+H HG PMTLSEL+  LP   VNQD 
Sbjct: 6    KENLSSQAKLWNFIYGFADSLVLKSAVQLDLANIIHNHGSPMTLSELSLHLPSQPVNQDA 65

Query: 390  LFRIMRYLVHMGLF--DLVDSDKKYALNPASNLLIKGQDKSLASFALLQYYEMD---AWH 554
            L+R++RYLVHM LF    +D + +Y L P +  L+KG DK +   A+L   + D    WH
Sbjct: 66   LYRVLRYLVHMKLFTKSSIDGELRYGLAPPAKFLVKGWDKCMLG-AILTITDKDFMAPWH 124

Query: 555  HLSAAV--EGGV-TPWEKCHGVDYREYFAKDSVANQLLSDAMTSHTSMVTEALVEGCKKA 725
            +L   +  +G   T +EK  G +  +Y A+    NQL ++ M + T ++  ALV+ C  +
Sbjct: 125  YLKEGILNDGSTSTAFEKALGTNIWDYMAEHPEKNQLFNEGMANDTRLIMSALVKEC--S 182

Query: 726  KXXXXXXXXXXXXXXXXXAARAVAKAFPGIKCAVFDLPHVIATAPECAEVERIEGDMFVS 905
                              A R +AKAFP IKC V+DLPHVIA +P   E+  I+GDMF  
Sbjct: 183  SMFDGITTIVDVGGGTGTAVRNIAKAFPHIKCTVYDLPHVIADSPGYTEINSIQGDMFKY 242

Query: 906  VPETDVVFMKSVLHDWGDEDCVKILKKCKEAIGGRKGGKVVILDIVLD 1049
            +P  D + MK +LHDW D++C++ILK+CK+A+  R GGKV+I+DI+LD
Sbjct: 243  IPNADAIMMKCILHDWDDKECIEILKRCKDAV-PRDGGKVIIIDIILD 289


>sp|Q9LEL6.1|6OMT_COPJA RecName: Full=(RS)-norcoclaurine 6-O-methyltransferase; AltName:
            Full=S-adenosyl-L-methionine:norcoclaurine
            6-O-methyltransferase; Short=6-OMT
            gi|9711914|dbj|BAB08004.1|
            S-adenosyl-L-methionine:norcoclaurine
            6-O-methyltransferase [Coptis japonica]
          Length = 347

 Score =  234 bits (598), Expect = 3e-59
 Identities = 123/288 (42%), Positives = 177/288 (61%), Gaps = 5/288 (1%)
 Frame = +3

Query: 201  EKMEEDMKAQAQVWRYVYGFAESLTLKCAIQLGIPDILHQHGRPMTLSELADSLPLPTVN 380
            E  ++++ +QA++W ++YGFAESL LKCA+QL + +I+H  G  MTLSEL+  LP   VN
Sbjct: 2    EVKKDNLSSQAKLWNFIYGFAESLVLKCAVQLDLANIIHNSGTSMTLSELSSRLPSQPVN 61

Query: 381  QDRLFRIMRYLVHMGLFDL--VDSDKKYALNPASNLLIKGQDKSLAS--FALLQYYEMDA 548
            +D L+R+MRYLVHM LF    +D + +Y L P +  L+KG DK +     A+     M  
Sbjct: 62   EDALYRVMRYLVHMKLFTKASIDGELRYGLAPPAKYLVKGWDKCMVGSILAITDKDFMAP 121

Query: 549  WHHLSAAVEG-GVTPWEKCHGVDYREYFAKDSVANQLLSDAMTSHTSMVTEALVEGCKKA 725
            WH+L   + G   T +EK  G +   Y A+    NQL ++AM + + ++  ALV+ C   
Sbjct: 122  WHYLKDGLSGESGTAFEKALGTNIWGYMAEHPEKNQLFNEAMANDSRLIMSALVKEC--G 179

Query: 726  KXXXXXXXXXXXXXXXXXAARAVAKAFPGIKCAVFDLPHVIATAPECAEVERIEGDMFVS 905
                              A R +A AFP IKC V+DLPHVIA +P  +EV  + GDMF  
Sbjct: 180  NIFNGITTLVDVGGGTGTAVRNIANAFPHIKCTVYDLPHVIADSPGYSEVHCVAGDMFKF 239

Query: 906  VPETDVVFMKSVLHDWGDEDCVKILKKCKEAIGGRKGGKVVILDIVLD 1049
            +P+ D + MK +LHDW D++C++ILK+CKEA+   KGGKV+I+DIVL+
Sbjct: 240  IPKADAIMMKCILHDWDDKECIEILKRCKEAV-PVKGGKVIIVDIVLN 286


>gb|ACO90250.1| norcoclaurine 6-O-methyltransferase-like protein [Thalictrum flavum]
          Length = 346

 Score =  234 bits (597), Expect = 4e-59
 Identities = 119/286 (41%), Positives = 172/286 (60%), Gaps = 7/286 (2%)
 Frame = +3

Query: 213  EDMKAQAQVWRYVYGFAESLTLKCAIQLGIPDILHQHGRPMTLSELADSLPLPTVNQDRL 392
            ED+ +QA++W Y+YGFA+SL LKCA+QL + +I+H HG PMTLSEL+  LP   VNQD L
Sbjct: 2    EDLSSQAKLWNYIYGFADSLVLKCAVQLDLANIIHDHGTPMTLSELSSRLPSQPVNQDAL 61

Query: 393  FRIMRYLVHMGLF--DLVDSDKKYALNPASNLLIKGQDKSLASFALLQYYE--MDAWHHL 560
            +R+MRYLVH+ LF    +D + +Y L P +  L+KG D  +    LL      M  +H++
Sbjct: 62   YRVMRYLVHIKLFTKSSIDGELRYGLAPPAKFLVKGWDNCMIGSILLMVDTDFMAPYHYI 121

Query: 561  SAAV---EGGVTPWEKCHGVDYREYFAKDSVANQLLSDAMTSHTSMVTEALVEGCKKAKX 731
               +      +T +EK  G +  EY A+    NQL ++ M + + +    L++ C  +  
Sbjct: 122  KDEILNDGSSITAFEKASGTNIWEYLAEHPEKNQLFNEGMANESRLTMSGLMKDC--SST 179

Query: 732  XXXXXXXXXXXXXXXXAARAVAKAFPGIKCAVFDLPHVIATAPECAEVERIEGDMFVSVP 911
                              + +AKAFP IK  V+DLPHVIA AP   E+  +EGDMF  +P
Sbjct: 180  FEGLTTLVDVGGGTGTTVKYIAKAFPNIKYTVYDLPHVIADAPGDTEINFVEGDMFKYIP 239

Query: 912  ETDVVFMKSVLHDWGDEDCVKILKKCKEAIGGRKGGKVVILDIVLD 1049
              D + MK VLHDW D +C++ILK+CK+A+  R GGKV+I+D+VL+
Sbjct: 240  NADAILMKGVLHDWDDNECIEILKRCKDAV-PRDGGKVIIIDVVLN 284


>gb|ACO90225.1| putative norcoclaurine 6-O-methyltransferase [Papaver bracteatum]
          Length = 357

 Score =  230 bits (587), Expect = 6e-58
 Identities = 118/294 (40%), Positives = 177/294 (60%), Gaps = 14/294 (4%)
 Frame = +3

Query: 210  EEDMKAQAQVWRYVYGFAESLTLKCAIQLGIPDILHQHGRPMTLSELADSLPLPT-VNQD 386
            + D + QA +W+ +YGFAESL LKCA+QL I + +H HG+PM+LSELA  LP+   VN D
Sbjct: 6    QTDQENQAIIWKQIYGFAESLVLKCAVQLEIAETIHNHGKPMSLSELASKLPIDQPVNID 65

Query: 387  RLFRIMRYLVHMGLFDLVDS-----------DKKYALNPASNLLIKGQDKSLASFALLQY 533
            RL+R+MR+LVHM LF+  +            + KY+L P +  LI+G ++S+  + L   
Sbjct: 66   RLYRVMRFLVHMKLFNKENISILSGETAQVVEDKYSLAPPAKYLIRGSEQSMVPWVLGIT 125

Query: 534  YE--MDAWHHLSAAVEGGVTPWEKCHGVDYREYFAKDSVANQLLSDAMTSHTSMVTEALV 707
             E  +  WH L   + G    +EK  G  + +Y +++   NQ+ ++ M   + +VT ALV
Sbjct: 126  DEDLVAPWHWLKEGITGNCNVFEKVLGKSHADYMSENPKKNQMFNELMACDSRLVTSALV 185

Query: 708  EGCKKAKXXXXXXXXXXXXXXXXXAARAVAKAFPGIKCAVFDLPHVIATAPECAEVERIE 887
              C+                    A  A++KAFP I+C +FDLPHVI  +PE   V +  
Sbjct: 186  NECRSV-FSDGINTLVDVGGGTGTAVSAISKAFPNIQCTLFDLPHVIGDSPEIPNVTKTS 244

Query: 888  GDMFVSVPETDVVFMKSVLHDWGDEDCVKILKKCKEAIGGRKGGKVVILDIVLD 1049
            GDMF S+P  D +FMK++LHDW D++CV+ILK+CKE +    GGKV+++++V+D
Sbjct: 245  GDMFQSIPSADAIFMKNILHDWNDDECVQILKRCKEVVS--VGGKVILVEMVMD 296


>gb|AFB74613.1| O-methyltransferase 3 [Papaver somniferum]
            gi|388571230|gb|AFK73711.1| O-methyltransferase [Papaver
            somniferum]
          Length = 339

 Score =  221 bits (562), Expect = 5e-55
 Identities = 117/281 (41%), Positives = 170/281 (60%), Gaps = 3/281 (1%)
 Frame = +3

Query: 216  DMKAQAQVWRYVYGFAESLTLKCAIQLGIPDILHQHGRPMTLSELADSLPLPTVNQDRLF 395
            D + QA++W+ ++GFAESL LKCA+QL I + LH + +PM+LSELA  LP   VN+DRL+
Sbjct: 8    DQENQAKIWKQIFGFAESLVLKCAVQLEIAETLHNNVKPMSLSELASKLPAQPVNEDRLY 67

Query: 396  RIMRYLVHMGLFDLVDSDKKYALNPASNLLIKGQDKSLASFALLQYYEMD---AWHHLSA 566
            RI+ +LVHM LF+   + +KY+L P +  L+KG +KS+   ++L   + D    W+HL  
Sbjct: 68   RILHFLVHMKLFNKDATTQKYSLAPPAKYLLKGWEKSMVP-SILSVTDKDFTAPWNHLGD 126

Query: 567  AVEGGVTPWEKCHGVDYREYFAKDSVANQLLSDAMTSHTSMVTEALVEGCKKAKXXXXXX 746
             + G    +EK  G   R Y  ++   +QL ++ M   T +   ALV  CK         
Sbjct: 127  GLTGNCNAFEKALGKGIRVYMRENPEKDQLFNEGMACDTRLFASALVNECKSI-FSDGIN 185

Query: 747  XXXXXXXXXXXAARAVAKAFPGIKCAVFDLPHVIATAPECAEVERIEGDMFVSVPETDVV 926
                       A +A++KAFP IKC + DLP V       ++  +I  D+F SVP  D +
Sbjct: 186  TLAGVGRGTGTAVKAISKAFPDIKCTIHDLPEV------TSKNSKIPRDVFKSVPSADAI 239

Query: 927  FMKSVLHDWGDEDCVKILKKCKEAIGGRKGGKVVILDIVLD 1049
            FMKS+LH+W DE+C++ILK+CKEAI   KGGKV+I D+V+D
Sbjct: 240  FMKSILHEWNDEECIQILKRCKEAI--PKGGKVIIADVVID 278


>sp|Q8H9A8.1|COOMT_COPJA RecName: Full=Columbamine O-methyltransferase; Short=CoOMT; AltName:
            Full=Tetrahydrocolumbamine 2-O-methyltransferase
            gi|24210466|dbj|BAC22084.1| columbamine
            O-methyltransferase [Coptis japonica]
          Length = 351

 Score =  219 bits (558), Expect = 1e-54
 Identities = 115/286 (40%), Positives = 171/286 (59%), Gaps = 6/286 (2%)
 Frame = +3

Query: 210  EEDMKAQAQVWRYVYGFAESLTLKCAIQLGIPDILHQHGRPMTLSELADSLPLPTVNQDR 389
            ++++KAQAQVW++++GFAE++ L+  + LGIPDI+H +G P+TLS+L   LPL + + DR
Sbjct: 10   DDEIKAQAQVWKHMFGFAETIMLRSTVSLGIPDIIHNNG-PVTLSQLVTHLPLKSTSIDR 68

Query: 390  LFRIMRYLVHMGLF----DLVDSDKKYALNPASNLLIKGQDKSLASFALLQYY--EMDAW 551
                MRYLVHM LF    D +  + KY L PAS LL+ G  KSLA + +LQ +  E   W
Sbjct: 69   FHHFMRYLVHMQLFTISTDQITKEDKYELTPASKLLVHGHQKSLAPYVMLQTHPEEFSVW 128

Query: 552  HHLSAAVEGGVTPWEKCHGVDYREYFAKDSVANQLLSDAMTSHTSMVTEALVEGCKKAKX 731
             H+   ++G    WE  +     E    D   N++L+DAMTSH++ +  ALV G  K   
Sbjct: 129  SHVINVLDGKKPYWES-NDTSMYEKTEGDPEINEILNDAMTSHSTFMLPALVSGLMKENV 187

Query: 732  XXXXXXXXXXXXXXXXAARAVAKAFPGIKCAVFDLPHVIATAPECAEVERIEGDMFVSVP 911
                             A+ +  AFP +KC+V DL HVI    +  +++ + GDMF S+P
Sbjct: 188  LDGVASIVDVGGNSGVVAKGIVDAFPHVKCSVMDLNHVIERVIKNPKLDYVAGDMFTSIP 247

Query: 912  ETDVVFMKSVLHDWGDEDCVKILKKCKEAIGGRKGGKVVILDIVLD 1049
              D + +KS LH++ D+DC+KIL   KEA+    GGKV++++IV+D
Sbjct: 248  NADAILLKSTLHNYEDDDCIKILNIAKEALPS-TGGKVILVEIVVD 292


>sp|Q9LEL5.1|4OMT_COPJA RecName: Full=3'-hydroxy-N-methyl-(S)-coclaurine
            4'-O-methyltransferase; AltName:
            Full=S-adenosyl-L-methionine:3'-hydroxy-N-
            methylcoclaurine 4'-O-methyltransferase; Short=4'-OMT
            gi|9711916|dbj|BAB08005.1|
            S-adenosyl-L-methionine:3'-hydroxy-N-methylcocla urine
            4'-O-methyltransferase [Coptis japonica]
          Length = 350

 Score =  219 bits (557), Expect = 2e-54
 Identities = 115/283 (40%), Positives = 166/283 (58%), Gaps = 5/283 (1%)
 Frame = +3

Query: 216  DMKAQAQVWRYVYGFAESLTLKCAIQLGIPDILHQHGRPMTLSELADSLPLPTVNQDRLF 395
            D+KAQA VW+ +YGFA+SL L+CA++LGI DI+  + +PM L++LA  LP+  VN D L+
Sbjct: 11   DIKAQAHVWKIIYGFADSLVLRCAVELGIVDIIDNNNQPMALADLASKLPVSDVNCDNLY 70

Query: 396  RIMRYLVHMGLFDLVDSD---KKYALNPASNLLIKGQDKSLASFAL--LQYYEMDAWHHL 560
            RI+RYLV M +  +  SD   KKYAL P + LL +   +S+    L   Q   M  WH +
Sbjct: 71   RILRYLVKMEILRVEKSDDGQKKYALEPIATLLSRNAKRSMVPMILGMTQKDFMTPWHSM 130

Query: 561  SAAVEGGVTPWEKCHGVDYREYFAKDSVANQLLSDAMTSHTSMVTEALVEGCKKAKXXXX 740
               +    T +EK  G+   EY       +QL ++ M   T ++T +L+ G +       
Sbjct: 131  KDGLSDNGTAFEKAMGMTIWEYLEGHPDQSQLFNEGMAGETRLLTSSLISGSRDM--FQG 188

Query: 741  XXXXXXXXXXXXXAARAVAKAFPGIKCAVFDLPHVIATAPECAEVERIEGDMFVSVPETD 920
                           +A++ AFP IKC +FDLPHVIA + +   +ERI GDMF SVP   
Sbjct: 189  IDSLVDVGGGNGTTVKAISDAFPHIKCTLFDLPHVIANSYDLPNIERIGGDMFKSVPSAQ 248

Query: 921  VVFMKSVLHDWGDEDCVKILKKCKEAIGGRKGGKVVILDIVLD 1049
             + +K +LHDW DED +KILK+C+ A+  + GGKV+I+D+ LD
Sbjct: 249  AIILKLILHDWNDEDSIKILKQCRNAV-PKDGGKVIIVDVALD 290


>gb|AAU20768.1| 3'-hydroxy-N-methyl-(S)-coclaurine 4'-O-methyltransferase [Thalictrum
            flavum subsp. glaucum]
          Length = 348

 Score =  218 bits (556), Expect = 3e-54
 Identities = 114/281 (40%), Positives = 168/281 (59%), Gaps = 3/281 (1%)
 Frame = +3

Query: 216  DMKAQAQVWRYVYGFAESLTLKCAIQLGIPDILHQHGRPMTLSELADSLPLPTVNQDRLF 395
            D+KAQA VW+ +YGFA+SL L+CA++LGI DI+  + +P+ L++LA  LP+  VN D LF
Sbjct: 12   DIKAQAHVWKIIYGFADSLVLRCAVELGIFDIIDNNNQPIPLADLASKLPISNVNLDNLF 71

Query: 396  RIMRYLVHMGLFDLVDSDKKYALNPASNLLIKGQDKSLASFAL--LQYYEMDAWHHL-SA 566
            RI+RYLV M L     +D KYAL P + L+++ + +S+    L   Q   M  WH +   
Sbjct: 72   RILRYLVKMELLSYA-ADDKYALEPIAKLVLRNEKRSMVPMVLGMTQKDFMTPWHSMKDG 130

Query: 567  AVEGGVTPWEKCHGVDYREYFAKDSVANQLLSDAMTSHTSMVTEALVEGCKKAKXXXXXX 746
              + GVT +EK  G+   EY       +QL ++ M   T ++T +L+ G K         
Sbjct: 131  LTDNGVTAFEKAMGMTIWEYLEGHPDQSQLFNEGMAGETRLLTSSLISGSK--DMFQSID 188

Query: 747  XXXXXXXXXXXAARAVAKAFPGIKCAVFDLPHVIATAPECAEVERIEGDMFVSVPETDVV 926
                         +A++ AFP IKC +FDLPHVIA + +   +ERI GDMF  +P    +
Sbjct: 189  SLVDVGGGNGTTIKAISVAFPHIKCTLFDLPHVIANSYDHPNIERIGGDMFKGMPSAQAI 248

Query: 927  FMKSVLHDWGDEDCVKILKKCKEAIGGRKGGKVVILDIVLD 1049
             +K +LHDW DED +KILK+C++A+  + GGKV+I+D+ LD
Sbjct: 249  LLKLILHDWNDEDSIKILKQCRKAV-PKDGGKVIIVDVALD 288


>gb|ABY75613.1| S-adenosyl-L-methionine:3'-hydroxy-N-methylcoclaurine
            4'-O-methyltransferase [Coptis chinensis]
          Length = 350

 Score =  218 bits (555), Expect = 3e-54
 Identities = 115/283 (40%), Positives = 166/283 (58%), Gaps = 5/283 (1%)
 Frame = +3

Query: 216  DMKAQAQVWRYVYGFAESLTLKCAIQLGIPDILHQHGRPMTLSELADSLPLPTVNQDRLF 395
            D+KAQA VW+ +YGFA+SL L+CA++LGI DI+  + +PM L++LA  LP+  VN D L+
Sbjct: 11   DIKAQAHVWKIIYGFADSLVLRCAVELGIVDIVDNNNQPMALADLASKLPVSNVNCDNLY 70

Query: 396  RIMRYLVHMGLFDLVDSD---KKYALNPASNLLIKGQDKSLASFAL--LQYYEMDAWHHL 560
            RI+RYLV M +  +  SD   KKYAL P + LL +   +S+    L   Q   M  WH +
Sbjct: 71   RILRYLVKMEILRVEKSDDGEKKYALEPIATLLSRNAKRSMVPMILGMTQKDFMTPWHSM 130

Query: 561  SAAVEGGVTPWEKCHGVDYREYFAKDSVANQLLSDAMTSHTSMVTEALVEGCKKAKXXXX 740
               +    T +EK  G+   EY       +QL ++ M   T ++T +L+ G +       
Sbjct: 131  KDGLSDNGTAFEKAMGMTIWEYLEGHPDQSQLFNEGMAGETRLLTSSLISGSRDM--FQG 188

Query: 741  XXXXXXXXXXXXXAARAVAKAFPGIKCAVFDLPHVIATAPECAEVERIEGDMFVSVPETD 920
                           +A++ AFP IKC +FDLPHVIA + +   +ERI GDMF SVP   
Sbjct: 189  IDSLVDVGGGNGTTVKAISDAFPHIKCTLFDLPHVIANSYDHPNIERIGGDMFKSVPSAQ 248

Query: 921  VVFMKSVLHDWGDEDCVKILKKCKEAIGGRKGGKVVILDIVLD 1049
             + +K +LHDW DED +KILK+C+ A+  + GGKV+I+D+ LD
Sbjct: 249  AILLKLILHDWNDEDSIKILKQCRNAV-PKDGGKVIIVDVALD 290


>ref|XP_006858228.1| hypothetical protein AMTR_s00062p00190100 [Amborella trichopoda]
            gi|548862331|gb|ERN19695.1| hypothetical protein
            AMTR_s00062p00190100 [Amborella trichopoda]
          Length = 353

 Score =  216 bits (551), Expect = 1e-53
 Identities = 113/284 (39%), Positives = 177/284 (62%), Gaps = 5/284 (1%)
 Frame = +3

Query: 210  EEDMKAQAQVWRYVYGFAESLTLKCAIQLGIPDILHQHGRPMTLSELADSLPLPTVNQDR 389
            +E+++AQA +W +++G A+++ L CA++LG+ DI+H HGRP+TL  LA  LP+  VN DR
Sbjct: 13   KEEVEAQAVIWEHMFGMAKTMALNCAVRLGLADIIHAHGRPITLFHLASLLPIQPVNPDR 72

Query: 390  LFRIMRYLVHMGLF----DLVDSDKKYALNPASNLLIKGQDKSLASFALLQYYEMDAWHH 557
            L R+MR+LVH  LF     L   ++ Y L P+S LL++  +KS++ FA +    +  W  
Sbjct: 73   LHRLMRFLVHTHLFAKTTGLNGDEETYWLTPSSQLLLRHAEKSMSGFARVHEMTVSPWLS 132

Query: 558  LSAAVEGGV-TPWEKCHGVDYREYFAKDSVANQLLSDAMTSHTSMVTEALVEGCKKAKXX 734
            L   +E GV + +EK +G+   EY A     N+  ++AM     +V  A+V GC+  +  
Sbjct: 133  LGPCLEEGVASAFEKTYGMSRWEYSASHPDENRAFNEAMACLARLVMPAIVGGCE--RLL 190

Query: 735  XXXXXXXXXXXXXXXAARAVAKAFPGIKCAVFDLPHVIATAPECAEVERIEGDMFVSVPE 914
                           A  A+AKAFP +K  ++DLPHV+AT  E   V+ + GDMF ++P+
Sbjct: 191  QGARSVVDVGGGTGTAVGALAKAFPSVKFTLYDLPHVVATVGELNGVDTVGGDMFSAIPK 250

Query: 915  TDVVFMKSVLHDWGDEDCVKILKKCKEAIGGRKGGKVVILDIVL 1046
             DVVF+  +LHDWGD++C++ILK+ ++AI   + GKV+I+D+VL
Sbjct: 251  ADVVFLMRILHDWGDKECLEILKQIRKAI--PEEGKVIIVDVVL 292


>gb|ACN88562.1| norreticuline-7-O-methyltransferase [Papaver somniferum]
          Length = 357

 Score =  216 bits (551), Expect = 1e-53
 Identities = 114/291 (39%), Positives = 168/291 (57%), Gaps = 13/291 (4%)
 Frame = +3

Query: 216  DMKAQAQVWRYVYGFAESLTLKCAIQLGIPDILHQHGRPMTLSELADSLPLPT-VNQDRL 392
            D + QA +W+ +YGF+ESL LKCA+Q  I + +H HG PM++ ELA  LP+   VN DRL
Sbjct: 8    DQENQAIIWKQIYGFSESLLLKCAVQCEIAETIHNHGTPMSILELAAKLPIDQPVNIDRL 67

Query: 393  FRIMRYLVHMGLFD----------LVDSDKKYALNPASNLLIKGQDKSLASFAL--LQYY 536
            +R+MRYLVH  LF+           V   +KY L P +  LI+G  +S+    L  +   
Sbjct: 68   YRVMRYLVHQKLFNKEVISTLNGGTVQVTEKYWLAPPAKYLIRGSQQSMVPSVLGIIDED 127

Query: 537  EMDAWHHLSAAVEGGVTPWEKCHGVDYREYFAKDSVANQLLSDAMTSHTSMVTEALVEGC 716
                WH L  ++ G    +E   G     Y +++   NQ+ + AM   + +VT  LV  C
Sbjct: 128  MFAPWHILKDSLTGECNIFETALGKSISVYMSENPEMNQISNGAMAFDSGLVTSHLVNEC 187

Query: 717  KKAKXXXXXXXXXXXXXXXXXAARAVAKAFPGIKCAVFDLPHVIATAPECAEVERIEGDM 896
            K                    A RA++KAFP IKC +FDLPHVIA +PE   + ++ GDM
Sbjct: 188  KSV-FGDEIKTLVDVGGGTGTALRAISKAFPNIKCTLFDLPHVIADSPEIPTITKVSGDM 246

Query: 897  FVSVPETDVVFMKSVLHDWGDEDCVKILKKCKEAIGGRKGGKVVILDIVLD 1049
            F S+P  D +FMK++LHDW D++C++ILK+CK+ +    GGK++++++VLD
Sbjct: 247  FKSIPSADAIFMKNILHDWNDDECIQILKRCKDVVSA--GGKLIMVEMVLD 295


>ref|XP_002278127.1| PREDICTED: isoflavone-7-O-methyltransferase 9 [Vitis vinifera]
          Length = 354

 Score =  213 bits (543), Expect = 8e-53
 Identities = 115/285 (40%), Positives = 172/285 (60%), Gaps = 7/285 (2%)
 Frame = +3

Query: 213  EDMKAQAQVWRYVYGFAESLTLKCAIQLGIPDILHQHGRPMTLSELADSLPLPTVNQDRL 392
            E  +AQ+ ++++V+ F +S++LKCA+QLGIPD +H H +P+TL ELA ++ +P     RL
Sbjct: 11   ELFEAQSFIYKHVFSFMDSMSLKCAVQLGIPDAIHNHNQPITLPELASAIQVPPEKTSRL 70

Query: 393  FRIMRYLVHMGLFDLVDSDKK---YALNPASNLLIKGQDKSLASFAL--LQYYEMDAWHH 557
             ++MR LVH G F +   D+    Y L P S LL+KG   SLA   L  L    +  WH 
Sbjct: 71   HQLMRLLVHSGFFAMQKVDENQEGYVLTPPSRLLVKGNATSLAPIVLGMLDPVLVTPWHF 130

Query: 558  LSAAVEGG-VTPWEKCHGVDYREYFAKDSVANQLLSDAMTSHTSMVTEALVEGCKKAKXX 734
            L + ++G  +T +E  HG+D   Y  ++     L+ + M + + M++ A+ E CK+    
Sbjct: 131  LGSWLQGSSLTAFEAAHGMDLWNYGNQNPEFFSLIGEIMATDSRMMSLAIRE-CKEI--F 187

Query: 735  XXXXXXXXXXXXXXXAARAVAKAFPGIKCAVFDLPHVIATAPECAEVERIEGDMFVSVPE 914
                            AR + +AFP +KC V DLP V+A  P+   ++ + GDMF S+P 
Sbjct: 188  EGLSSLVDVGGGTGTMARGICEAFPHLKCTVLDLPQVVANLPKSENLDYVGGDMFQSIPS 247

Query: 915  TDVVFMKSVLHDWGDEDCVKILKKCKEAI-GGRKGGKVVILDIVL 1046
             D +F+KSVLH+WGDEDCVKILK+C+EAI    +GGKV+I+D+VL
Sbjct: 248  ADAIFIKSVLHNWGDEDCVKILKRCREAIPSSAEGGKVIIIDLVL 292


>ref|XP_006368013.1| PREDICTED: trans-resveratrol di-O-methyltransferase-like [Solanum
            tuberosum]
          Length = 353

 Score =  212 bits (540), Expect = 2e-52
 Identities = 114/288 (39%), Positives = 167/288 (57%), Gaps = 5/288 (1%)
 Frame = +3

Query: 201  EKMEEDMKAQAQVWRYVYGFAESLTLKCAIQLGIPDILHQHGRPMTLSELADSLPL-PTV 377
            ++  E + AQA +  +V  +  S++LKCAIQLGIPDI+H HGR MT S+L ++LP+  + 
Sbjct: 9    DETNEVLAAQAHILNHVLNYVNSMSLKCAIQLGIPDIIHSHGRAMTRSDLVNALPINKSK 68

Query: 378  NQDRLFRIMRYLVHMGLFDLVDSDKKYALNPASNLLIKGQDKSLASF--ALLQYYEMDAW 551
              + ++R+MR L+H G F  ++ ++ Y L P S LL+K +  +LA F  A L    MD W
Sbjct: 69   GHECIYRLMRILIHTGFF--IEGEEGYLLTPTSRLLLKNEPLNLAPFVQAHLDPILMDPW 126

Query: 552  HHLSA-AVEGGVTPWEKCHGVDYREYFAKDSVANQLLSDAMTSHTSMVTEALVEGCKKAK 728
            H L      G  TP+   HG    +Y   D   N++ ++AM S   ++   L++  K+  
Sbjct: 127  HSLGEWFANGDSTPFATAHGKPLFDYAGDDPRLNRIFNEAMESDARLIMSVLIKNGKRV- 185

Query: 729  XXXXXXXXXXXXXXXXXAARAVAKAFPGIKCAVFDLPHVIATAPECAEVERIEGDMFVSV 908
                              A+A++ AFP +KC+VFDLPHV+        +  I GDMF SV
Sbjct: 186  -FEGLTSLVDVGGGIGTVAKAISNAFPELKCSVFDLPHVVEGLEGGNNLSYITGDMFKSV 244

Query: 909  PETDVVFMKSVLHDWGDEDCVKILKKCKEAIGGRK-GGKVVILDIVLD 1049
            P  D + +K +LHDW DEDC KILKKCKEAI  ++ GGKV+++D V+D
Sbjct: 245  PSADAILLKWILHDWSDEDCAKILKKCKEAIPSKENGGKVIVIDTVID 292


>emb|CAN75970.1| hypothetical protein VITISV_009881 [Vitis vinifera]
          Length = 354

 Score =  212 bits (539), Expect = 2e-52
 Identities = 115/285 (40%), Positives = 172/285 (60%), Gaps = 7/285 (2%)
 Frame = +3

Query: 213  EDMKAQAQVWRYVYGFAESLTLKCAIQLGIPDILHQHGRPMTLSELADSLPLPTVNQDRL 392
            E  +AQ+ ++++V+ F +S++LKCA+QLGIPD +H H +P+TL ELA ++ +P     RL
Sbjct: 11   ELFEAQSFIYKHVFSFMDSMSLKCAVQLGIPDAIHNHNQPITLPELASAIQVPPEKTSRL 70

Query: 393  FRIMRYLVHMGLFDLVDSDKK---YALNPASNLLIKGQDKSLASFAL--LQYYEMDAWHH 557
             ++MR LVH G F +   D+    Y L P S LL+KG   SLA   L  L    +  WH 
Sbjct: 71   HQLMRLLVHSGFFAMQKVDENQEGYVLTPPSRLLVKGNATSLAPIVLGMLDPVLVTPWHF 130

Query: 558  LSAAVEGG-VTPWEKCHGVDYREYFAKDSVANQLLSDAMTSHTSMVTEALVEGCKKAKXX 734
            L + ++G  +T +E  HG+D   Y  ++      + + M + + M++ A+ E CK+    
Sbjct: 131  LGSWLQGSSLTAFEAAHGMDLWNYGNQNPEXFSXIGEIMATDSRMMSLAIRE-CKEI--F 187

Query: 735  XXXXXXXXXXXXXXXAARAVAKAFPGIKCAVFDLPHVIATAPECAEVERIEGDMFVSVPE 914
                            AR + +AFP +KC V DLP V+A  P+   ++ + GDMF S+P 
Sbjct: 188  EGXSSLVDVGGGTGTMARGICEAFPHLKCTVLDLPQVVANLPKSENLDYVGGDMFQSIPS 247

Query: 915  TDVVFMKSVLHDWGDEDCVKILKKCKEAI-GGRKGGKVVILDIVL 1046
             D +F+KSVLH+WGDEDCVKILK+C+EAI    +GGKV+I+D+VL
Sbjct: 248  ADAIFIKSVLHNWGDEDCVKILKRCREAIPSSAEGGKVIIIDLVL 292


>sp|Q6VMW0.1|Q8OMT_MENPI RecName: Full=8-hydroxyquercetin 8-O-methyltransferase; AltName:
            Full=Flavonol 8-O-methyltransferase
            gi|38047395|gb|AAR09600.1| flavonoid
            8-O-methyltransferase [Mentha x piperita]
          Length = 366

 Score =  212 bits (539), Expect = 2e-52
 Identities = 113/297 (38%), Positives = 165/297 (55%), Gaps = 17/297 (5%)
 Frame = +3

Query: 210  EEDMKAQAQVWRYVYGFAESLTLKCAIQLGIPDILHQHGRPMTLSELADSLPLPTVNQDR 389
            +E ++AQA VW ++Y +  S++LKCAIQLGIPD +H+HG P+TLS+LAD+L +       
Sbjct: 11   QELLEAQAHVWNHIYSYINSMSLKCAIQLGIPDAIHKHGNPITLSQLADALNINKAKSHG 70

Query: 390  LFRIMRYLVHMGLFDLV------------DSDKKYALNPASNLLIKGQDKSLASFALLQY 533
            LFR+MR LVH G FD V            + +  Y+L PAS LL++ +  S+A FAL   
Sbjct: 71   LFRLMRILVHSGFFDKVKVKVKVEGEDEEEEEDAYSLTPASRLLLRSEPLSVAPFALAMS 130

Query: 534  YEM--DAWHHLSAAVEG-GVTPWEKCHGVDYREYFAKDSVANQLLSDAMTSHTSMVTEAL 704
              +  + WHHLS       V  ++  +G+ + EY   D   N L ++AM      V   L
Sbjct: 131  DPVYTETWHHLSEWFRNDAVAAFDTKYGMTFPEYAVADDRLNVLFNEAMACDAGFVNSIL 190

Query: 705  VEGCKKAKXXXXXXXXXXXXXXXXXAARAVAKAFPGIKCAVFDLPHVIATAPECAEVERI 884
               C+  +                  A+ +A AFPG++C V DLP+V+        +  +
Sbjct: 191  TTECR--EIFDGLESMVDVGGGTGATAKGIAAAFPGMECTVLDLPNVVGGLKGSENLSFV 248

Query: 885  EGDMFVSVPETDVVFMKSVLHDWGDEDCVKILKKCKEAIGGRKGG--KVVILDIVLD 1049
             GDMF  +P  D +FMK +LHDW DE+CVKILKKCKEAI        K+++++IV++
Sbjct: 249  SGDMFDFIPHADAIFMKFILHDWNDEECVKILKKCKEAISRSNNSCRKIILVEIVME 305


>gb|AAR09603.1| O-methyltransferase [Mentha x piperita]
          Length = 361

 Score =  211 bits (538), Expect = 3e-52
 Identities = 117/291 (40%), Positives = 169/291 (58%), Gaps = 11/291 (3%)
 Frame = +3

Query: 207  MEEDMKAQAQVWRYVYGFAESLTLKCAIQLGIPDILHQHGRPMTLSELADSLPLPTVNQD 386
            +EE + A+A VW +++ +  S++LK A+QLGIPDI+H+HG P+TLS+LAD+L +     D
Sbjct: 11   VEELLDAEAHVWNHIFSYINSMSLKSALQLGIPDIIHKHGNPITLSQLADALNINKAKTD 70

Query: 387  RLFRIMRYLVHMGLFDLVD-----SDKKYALNPASNLLIKGQDKSLASF--ALLQYYEMD 545
             LFR+MR L H   FD V       ++ Y+L  AS LL++ +  SLA +  A+L    MD
Sbjct: 71   GLFRLMRLLEHSKFFDKVKVEGEGEEEAYSLTRASRLLLRDEPSSLAPYIRAMLDPNFMD 130

Query: 546  AWHHLSAAVEGGV-TPWEKCHGVDYREYFAKDSVANQLLSDAMTSHTSMVTEALVEGCKK 722
             +HHLS  +     +P+E  HG    EY   +   NQL + AM +   +VT  LV+ C+ 
Sbjct: 131  PFHHLSEWLGSECPSPFEFKHGRSLWEYAGIEERWNQLFNQAMANDAKLVTSILVKECRH 190

Query: 723  AKXXXXXXXXXXXXXXXXXAARAVAKAFPGIKCAVFDLPHVIATAPECAEVERIEGDMFV 902
                                A+ VA AFPG+K  V DLPHV+A       +  + GDMF 
Sbjct: 191  I--FQGLESLVDVGGGAGTVAKVVADAFPGLKAVVLDLPHVVADLATSENLRYVSGDMFE 248

Query: 903  SVPETDVVFMKSVLHDWGDEDCVKILKKCKEAIGGRK---GGKVVILDIVL 1046
             +P  D V +K +LH+W DE+C+KIL+KCKEAI   K   GGKV+++D++L
Sbjct: 249  DIPRADAVLLKWILHNWSDEECIKILEKCKEAITPSKNNNGGKVIVIDMIL 299