BLASTX 2.2.25 [Feb-01-2011]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= Sinomenium21_contig00025043
         (2270 letters)

Database: ./nr 
           38,876,450 sequences; 13,856,398,315 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

ref|XP_002264336.1| PREDICTED: reticuline oxidase-like [Vitis vi...   498   e-138
ref|XP_003555533.1| PREDICTED: reticuline oxidase-like [Glycine ...   496   e-137
dbj|BAM44344.1| berberine bridge enzyme [Coptis japonica]             494   e-137
gb|AAD17487.1| berberine bridge enzyme [Berberis stolonifera]         493   e-136
gb|AAU20769.1| berberine bridge enzyme [Thalictrum flavum subsp....   487   e-134
ref|XP_003634619.1| PREDICTED: LOW QUALITY PROTEIN: reticuline o...   486   e-134
gb|ACJ76783.1| berberine bridge enzyme 1 [Argemone mexicana]          486   e-134
ref|XP_007099511.1| FAD-binding Berberine family protein [Theobr...   485   e-134
ref|XP_003535410.1| PREDICTED: reticuline oxidase-like [Glycine ...   484   e-134
ref|XP_002533924.1| d-lactate dehydrogenase, putative [Ricinus c...   484   e-134
ref|XP_006371334.1| hypothetical protein POPTR_0019s09180g [Popu...   483   e-133
sp|P30986.1|RETO_ESCCA RecName: Full=Reticuline oxidase; AltName...   479   e-132
pdb|4EC3|A Chain A, Structure Of Berberine Bridge Enzyme, H174a ...   479   e-132
pdb|3GSY|A Chain A, Structure Of Berberine Bridge Enzyme In Comp...   479   e-132
pdb|3FW9|A Chain A, Structure Of Berberine Bridge Enzyme In Comp...   479   e-132
pdb|3D2D|A Chain A, Structure Of Berberine Bridge Enzyme In Comp...   479   e-132
gb|ACJ76784.1| berberine bridge enzyme 2 [Argemone mexicana]          476   e-131
pdb|3FWA|A Chain A, Structure Of Berberine Bridge Enzyme, C166a ...   476   e-131
pdb|3FW8|A Chain A, Structure Of Berberine Bridge Enzyme, C166a ...   476   e-131
ref|XP_006478292.1| PREDICTED: reticuline oxidase-like [Citrus s...   476   e-131

>ref|XP_002264336.1| PREDICTED: reticuline oxidase-like [Vitis vinifera]
          Length = 540

 Score =  498 bits (1281), Expect = e-138
 Identities = 255/504 (50%), Positives = 342/504 (67%), Gaps = 11/504 (2%)
 Frame = -3

Query: 1755 SCISTEGVNYTT--PYAQE----YHHSFGLAAYNLRVTSAYA-RPIAIILPETKERLAAT 1597
            SC++   VN  T  P+ Q     Y+     +  NLR     A +P+AI+LP+++E+L  T
Sbjct: 33   SCLTRHNVNNFTVLPHKQNESPAYYRLLNFSIQNLRYAVPTAPKPVAIVLPQSREQLVNT 92

Query: 1596 IVCCRKTSWAFTFRSGGHSLEGLSYSAGNDHPFVMIDLMKLNQVVVDLESKTAWVEGGAT 1417
            + CCR+  +    R GGHS EG S    + +PFV+ID+M LNQV+VDLES+TAWVEGGAT
Sbjct: 93   VSCCREGLFEIRVRCGGHSYEGTSSVVLDGNPFVIIDMMSLNQVLVDLESETAWVEGGAT 152

Query: 1416 LGEVYHAVGTLSNRLGFPAGYCPAVXXXXXXXXXXXGFMSRKYGLASDNVVDAILINADG 1237
            LGE Y+AV   SN  GF AG CP V           G +SRKYGLA+DNVVDA+LI+ADG
Sbjct: 153  LGETYYAVAEASNVHGFSAGSCPTVGVGGHISGGGFGLLSRKYGLAADNVVDALLIDADG 212

Query: 1236 QFLDRKSMGEDVFWAIRGGGAGSWGAVYSWKIRLVDVPETVTALRVTRHGSRSEAVKLLN 1057
            + +DR++MGEDVFWAIRGGG G WG VY+W+I+L+ VPE VT+  ++R G++    +L++
Sbjct: 213  RLVDREAMGEDVFWAIRGGGGGVWGIVYAWRIKLLKVPEIVTSCIMSRTGTKLHVAELVH 272

Query: 1056 KWQWVAPDLEDEFTLM----ASVIAESETSILTIFQGLYLGLKSSAVASITQVFPELEVV 889
            KWQ++AP LE  F L     A ++   ET +   F+G YLG +S A++ + QVFPEL + 
Sbjct: 273  KWQFIAPRLEPSFYLSVFVGAGLLGGKETGVSASFKGFYLGSRSKAMSILNQVFPELGIE 332

Query: 888  ASESKEMKWVESTAFFPDFTERFTVDDLKDRFATSDQKAYFKWKGDYVRNNISIEGIEGM 709
              E +EM W+ES A+F D  E  ++ +L++R+  +  K YFK K DYVR  IS++G+   
Sbjct: 333  IEECREMSWIESIAYFGDLAEGSSISELRNRYLQA--KLYFKAKSDYVRTPISMKGLRTA 390

Query: 708  LDMLMKEPHGQLQLMPYGGMMARTRSDATPYPHREGNLYSIGYLVTWNEDDNKRSDIYMD 529
            LD L KEP G + L PYGG M R  SDA  +PHR+GNL++I Y+V W E+D+  S  Y+D
Sbjct: 391  LDTLEKEPKGYVILDPYGGEMERIGSDAIAFPHRKGNLFAIQYMVAW-EEDSLMSYKYID 449

Query: 528  WVHGIHEYMTPFVSKGPRAAYVNELDLDLGVMDWGNHNISANELIELGRSWGEKYFLLNY 349
            W+ G ++ MTP VS GPRAAYVN +DLDLGVM+  N + S+ + +E+ R+WGEKYFL NY
Sbjct: 450  WIRGFYKSMTPHVSWGPRAAYVNYMDLDLGVMEMVNSSFSSGDPVEIARAWGEKYFLNNY 509

Query: 348  ERLVRAKTEIDPNNVFRHQQSIPP 277
            ERLVR KT IDPNNVF +QQ IPP
Sbjct: 510  ERLVRVKTLIDPNNVFNNQQGIPP 533


>ref|XP_003555533.1| PREDICTED: reticuline oxidase-like [Glycine max]
          Length = 550

 Score =  496 bits (1276), Expect = e-137
 Identities = 252/519 (48%), Positives = 334/519 (64%), Gaps = 23/519 (4%)
 Frame = -3

Query: 1764 NFFSCISTEGV----------NYTT-PYAQEYHHS-------FGLAAYNLRVTS-AYARP 1642
            + FSC S  G+          N+TT PY +  H S          +  NLR       +P
Sbjct: 21   SLFSCASLRGLASCLDNHNIKNFTTFPYKEHDHSSAYSYFKILNFSIQNLRFAEPVIPKP 80

Query: 1641 IAIILPETKERLAATIVCCRKTSWAFTFRSGGHSLEGLSYSAGNDHPFVMIDLMKLNQVV 1462
            IAI+LPE+ E+L  ++ CCR+ S     R GGHS EG SY A +  PFV+ID+M LN V 
Sbjct: 81   IAIVLPESLEQLQKSVACCREGSMEIRVRCGGHSYEGTSYVADDGTPFVIIDMMNLNHVW 140

Query: 1461 VDLESKTAWVEGGATLGEVYHAVGTLSNRLGFPAGYCPAVXXXXXXXXXXXGFMSRKYGL 1282
            VD+E++TAWVEGGATLGE Y+A+   SN  GF  G CP V           G +SRKYGL
Sbjct: 141  VDMETETAWVEGGATLGETYYAISQESNEHGFSGGSCPTVGVGGHIGGGGFGLLSRKYGL 200

Query: 1281 ASDNVVDAILINADGQFLDRKSMGEDVFWAIRGGGAGSWGAVYSWKIRLVDVPETVTALR 1102
            A+DNVVDA+L++A+G+  DR++MGEDVFWAIRGGG G WG +Y+WKI+++ VP+ VT+  
Sbjct: 201  AADNVVDALLVDANGKLFDRETMGEDVFWAIRGGGGGLWGIIYAWKIQVLKVPQVVTSFT 260

Query: 1101 VTRHGSRSEAVKLLNKWQWVAPDLEDEFTLMASVIA----ESETSILTIFQGLYLGLKSS 934
            V+R G++S    L++KWQ+VAP+LED+F L   V A       T + T F G YLG ++S
Sbjct: 261  VSRTGTKSHVANLVHKWQYVAPNLEDDFYLSCLVGAGLPQAKTTGLSTTFNGFYLGPRAS 320

Query: 933  AVASITQVFPELEVVASESKEMKWVESTAFFPDFTERFTVDDLKDRFATSDQKAYFKWKG 754
            A + + Q FPEL +   E  EM W++S  FF   ++  +V DLK+R+    +K YFK K 
Sbjct: 321  ATSILNQAFPELSIAEEECIEMSWIQSIVFFSGLSDGASVSDLKNRYL--QEKEYFKAKS 378

Query: 753  DYVRNNISIEGIEGMLDMLMKEPHGQLQLMPYGGMMARTRSDATPYPHREGNLYSIGYLV 574
            DYV+ N+ + GIE  LD+L KEP G + L PYGGMM    S++  +PHR GNL++I YL+
Sbjct: 379  DYVKKNVPLVGIETALDILEKEPKGYVVLDPYGGMMHNISSESIAFPHRRGNLFTIQYLI 438

Query: 573  TWNEDDNKRSDIYMDWVHGIHEYMTPFVSKGPRAAYVNELDLDLGVMDWGNHNISANELI 394
             W E DN +S  Y+DW+ G +  MTPFVS GPRAAY+N +D DLGVM+   +  +  + +
Sbjct: 439  YWKEADNDKSSDYVDWIRGFYAAMTPFVSWGPRAAYINYMDFDLGVMEGIGNGANMKDAV 498

Query: 393  ELGRSWGEKYFLLNYERLVRAKTEIDPNNVFRHQQSIPP 277
            E  R WGEKYFL NY+RLVRAKT IDPNNVF + Q IPP
Sbjct: 499  EHARVWGEKYFLSNYDRLVRAKTLIDPNNVFTNDQGIPP 537


>dbj|BAM44344.1| berberine bridge enzyme [Coptis japonica]
          Length = 533

 Score =  494 bits (1271), Expect = e-137
 Identities = 264/505 (52%), Positives = 335/505 (66%), Gaps = 5/505 (0%)
 Frame = -3

Query: 1776 EDDFNFFSCISTEGV-NYTTPYAQ--EYHHSFGLAAYNLRVT-SAYARPIAIILPETKER 1609
            EDD    SC+   GV NYTTP+    +Y     ++  N   T S + RP  IILPE+K++
Sbjct: 25   EDDLP--SCLILHGVSNYTTPFISNSDYDRLLYVSMQNQIFTRSTFPRPSVIILPESKDQ 82

Query: 1608 LAATIVCCRKTSWAFTFRSGGHSLEGLSYSAGNDHPFVMIDLMKLNQVVVDLESKTAWVE 1429
            L  TI CCR+ SW    RSGGHS EGLS++A  D PFV+ID+M LN V +DL+++TAW E
Sbjct: 83   LVNTISCCRRGSWTIRLRSGGHSYEGLSHTA--DSPFVIIDMMNLNGVSIDLDTQTAWAE 140

Query: 1428 GGATLGEVYHAVGTLSNRLGFPAGYCPAVXXXXXXXXXXXGFMSRKYGLASDNVVDAILI 1249
             GATLGE+YHA+G  S+ LGF AGYCP V           G MSRKYGLA+DNVVDAILI
Sbjct: 141  SGATLGEIYHAIGVSSDVLGFSAGYCPTVGSGGHISGGGFGMMSRKYGLAADNVVDAILI 200

Query: 1248 NADGQFLDRKSMGEDVFWAIRGGGAGSWGAVYSWKIRLVDVPETVTALRVTRHGSR-SEA 1072
            +A+G   DRKSMGEDVFWAIRGGG G WG VY+WK++L+ VP+ VT  ++T+H S   EA
Sbjct: 201  SANGALYDRKSMGEDVFWAIRGGGGGVWGVVYAWKLQLLPVPKHVTVFKLTKHTSEIDEA 260

Query: 1071 VKLLNKWQWVAPDLEDEFTLMASVIAESETSILTIFQGLYLGLKSSAVASITQVFPELEV 892
             KLL KWQ VAP+L+D+F+L     AE +   LT F GLYLG K  AV+S+ Q FPEL +
Sbjct: 261  SKLLYKWQLVAPNLDDDFSLAVLNGAEKDGFWLT-FLGLYLGPKEVAVSSMHQKFPELNL 319

Query: 891  VASESKEMKWVESTAFFPDFTERFTVDDLKDRFATSDQKAYFKWKGDYVRNNISIEGIEG 712
            ++ E KE+ WVE+ A      E   VD+L +RF   D +A FK K D+    I +EGI G
Sbjct: 320  LSEECKEVSWVEAFAQLAGLKE---VDELNNRFLKYDDRA-FKTKVDFAEVPIPLEGING 375

Query: 711  MLDMLMKEPHGQLQLMPYGGMMARTRSDATPYPHREGNLYSIGYLVTWNEDDNKRSDIYM 532
             L +L KE  G + +   GGMM R   D+ P+PHR G L  I Y+V W+ D++  S  Y+
Sbjct: 376  ALQILKKEQRGFMVMNGQGGMMGRISRDSIPFPHRSGMLSMIEYIVAWDMDEDFNSHEYI 435

Query: 531  DWVHGIHEYMTPFVSKGPRAAYVNELDLDLGVMDWGNHNISANELIELGRSWGEKYFLLN 352
            +W+H  ++YM  FV   PR  YVN +D D G +DW N +ISA++ IE+ R+WGEKYFL N
Sbjct: 436  NWLHQFYDYMGQFVGNNPRVGYVNHVDFDFGTIDWTNSSISASKAIEIARTWGEKYFLSN 495

Query: 351  YERLVRAKTEIDPNNVFRHQQSIPP 277
            Y+RLV AKT IDPNNVF H QSIPP
Sbjct: 496  YDRLVGAKTLIDPNNVFSHPQSIPP 520


>gb|AAD17487.1| berberine bridge enzyme [Berberis stolonifera]
          Length = 536

 Score =  493 bits (1270), Expect = e-136
 Identities = 262/514 (50%), Positives = 345/514 (67%), Gaps = 7/514 (1%)
 Frame = -3

Query: 1791 SITGREDDFNFFSCISTEGV-NYT---TPYAQEYHHSFGLAAYNLRVTSA-YARPIAIIL 1627
            +IT    D N  SC+++ GV N+T   T    +YH    ++  N   T   Y RP  IIL
Sbjct: 13   TITCTLGDVNLSSCLTSNGVSNFTALSTSSDSDYHRLLYVSMQNQIFTRPKYPRPSMIIL 72

Query: 1626 PETKERLAATIVCCRKTSWAFTFRSGGHSLEGLSYSAGNDHPFVMIDLMKLNQVVVDLES 1447
            P++KE LAA++VC  +  W    RSGGHS EGLSY A  D PFV+IDLM LN++ +DLES
Sbjct: 73   PQSKEELAASVVCSNRGLWTIRLRSGGHSYEGLSYVA--DTPFVVIDLMNLNRISIDLES 130

Query: 1446 KTAWVEGGATLGEVYHAVGTLSNRLGFPAGYCPAVXXXXXXXXXXXGFMSRKYGLASDNV 1267
            KTAWVE GATLGE+Y A+   S+ LGF  GYCP V           G MSRKYGLA+DNV
Sbjct: 131  KTAWVESGATLGEIYCAISEASDTLGFSGGYCPTVGSGGHISGGGFGMMSRKYGLAADNV 190

Query: 1266 VDAILINADGQFLDRKSMGEDVFWAIRGGGAGSWGAVYSWKIRLVDVPETVTALRVTRH- 1090
            +DA++++A+G  LDR SMGEDVFWAIRGGG G WGA+Y+WK++L+ VP+ VT  ++ ++ 
Sbjct: 191  IDALIVDANGAVLDRSSMGEDVFWAIRGGGGGVWGAIYAWKLQLLPVPKQVTVFKLMKNF 250

Query: 1089 GSRSEAVKLLNKWQWVAPDLEDEFTLMASVIAESETS-ILTIFQGLYLGLKSSAVASITQ 913
             +  EA K+L+KWQ VAP LED+FTL  SV+A ++T+ I   F GLYLG K  A++S+ Q
Sbjct: 251  DNIEEASKMLHKWQVVAPALEDDFTL--SVLAGADTNGIWFSFLGLYLGPKELAISSVDQ 308

Query: 912  VFPELEVVASESKEMKWVESTAFFPDFTERFTVDDLKDRFATSDQKAYFKWKGDYVRNNI 733
             FPEL +V  + KEM WVES A         +V+++ +RF   D +A FK K D+V+  I
Sbjct: 309  NFPELNLVMEDCKEMSWVESFAHLAGLN---SVEEMNNRFLKYDDRA-FKTKVDFVKEPI 364

Query: 732  SIEGIEGMLDMLMKEPHGQLQLMPYGGMMARTRSDATPYPHREGNLYSIGYLVTWNEDDN 553
             +EGI+G L ML KE  G +     GG+M+R  SD+TP+PHR+G L  + Y+V W+ D++
Sbjct: 365  PLEGIKGALTMLTKELRGFMAFNGQGGLMSRISSDSTPFPHRKGTLMMMEYIVAWDRDED 424

Query: 552  KRSDIYMDWVHGIHEYMTPFVSKGPRAAYVNELDLDLGVMDWGNHNISANELIELGRSWG 373
             +S  ++ W+HG + YM  F+   PR AYVN +DLDLG +DW N  I++N  IE+ R+WG
Sbjct: 425  AKSYEFIGWLHGFYNYMGQFLPSDPRIAYVNHVDLDLGRLDWTNSTIASN-AIEIARTWG 483

Query: 372  EKYFLLNYERLVRAKTEIDPNNVFRHQQSIPPKP 271
            EKYFL NYERLVRAKT IDP NVF H QSIPP P
Sbjct: 484  EKYFLSNYERLVRAKTLIDPKNVFHHPQSIPPMP 517


>gb|AAU20769.1| berberine bridge enzyme [Thalictrum flavum subsp. glaucum]
          Length = 535

 Score =  487 bits (1253), Expect = e-134
 Identities = 250/499 (50%), Positives = 331/499 (66%), Gaps = 6/499 (1%)
 Frame = -3

Query: 1755 SCISTEGV-NYTTPYAQE----YHHSFGLAAYNLRVT-SAYARPIAIILPETKERLAATI 1594
            SC++  GV NYTT  +      YH    ++  N   T S + +P  IILPE+ ++LA  I
Sbjct: 25   SCLTIHGVHNYTTHQSTSNSDAYHRLLYVSMQNQIFTRSTFPQPRVIILPESMDQLANVI 84

Query: 1593 VCCRKTSWAFTFRSGGHSLEGLSYSAGNDHPFVMIDLMKLNQVVVDLESKTAWVEGGATL 1414
             CC + SW    RSGGHS EGLS+ A  D+PFV+IDLM LN + +DL+++TAWVE GATL
Sbjct: 85   SCCTRGSWTIRLRSGGHSYEGLSHIA--DNPFVIIDLMNLNGISIDLDTQTAWVESGATL 142

Query: 1413 GEVYHAVGTLSNRLGFPAGYCPAVXXXXXXXXXXXGFMSRKYGLASDNVVDAILINADGQ 1234
            GE+YHA+G  S  + F AGYCP             G MSRKYGLA+DNVVDA+L++A+G 
Sbjct: 143  GEIYHAIGKSSGTMAFSAGYCPTGGSGGHIAPGGFGMMSRKYGLAADNVVDALLVDANGV 202

Query: 1233 FLDRKSMGEDVFWAIRGGGAGSWGAVYSWKIRLVDVPETVTALRVTRHGSRSEAVKLLNK 1054
             LDR+SMGEDVFWAIRGGG G WGAVY+WK++LV VP+ VT  R+ +H    +A KLL+K
Sbjct: 203  VLDRESMGEDVFWAIRGGGGGVWGAVYAWKLQLVPVPKNVTIFRLMKHSEVEDASKLLHK 262

Query: 1053 WQWVAPDLEDEFTLMASVIAESETSILTIFQGLYLGLKSSAVASITQVFPELEVVASESK 874
            WQ VAP LED+F+L        ++SI   F GLYLG K  A +S+ + FPEL ++  +  
Sbjct: 263  WQLVAPKLEDDFSLAVLAGTNKDSSIWLTFLGLYLGPKELASSSMHKKFPELNLLLEDCM 322

Query: 873  EMKWVESTAFFPDFTERFTVDDLKDRFATSDQKAYFKWKGDYVRNNISIEGIEGMLDMLM 694
            EM WVE+TA   +     +V +LKDRF   D +A FK K D+ +  I +EGI+G L++L 
Sbjct: 323  EMSWVEATA---ELAGLKSVSELKDRFLRYDDRA-FKTKVDFPKEAIPLEGIQGALEILK 378

Query: 693  KEPHGQLQLMPYGGMMARTRSDATPYPHREGNLYSIGYLVTWNEDDNKRSDIYMDWVHGI 514
            KE  G + +   GGMM R  +DA+P+PHR G L  + Y+V W++ ++  S+ ++ W+H +
Sbjct: 379  KEQRGFMVMNGQGGMMDRISTDASPFPHRSGTLSMVEYIVAWDKHEDLHSNEFIHWLHQL 438

Query: 513  HEYMTPFVSKGPRAAYVNELDLDLGVMDWGNHNISANELIELGRSWGEKYFLLNYERLVR 334
             +YM  FVS  PR  YVN +DLDLG +DW N  IS+   IE+ R+WGEKYF+ NY+RLVR
Sbjct: 439  FDYMGKFVSNNPRVGYVNHVDLDLGRIDWVNKTISSGRAIEIARTWGEKYFMSNYDRLVR 498

Query: 333  AKTEIDPNNVFRHQQSIPP 277
            AKT IDP NVF H QSIPP
Sbjct: 499  AKTMIDPKNVFNHPQSIPP 517


>ref|XP_003634619.1| PREDICTED: LOW QUALITY PROTEIN: reticuline oxidase-like [Vitis
            vinifera]
          Length = 712

 Score =  486 bits (1250), Expect = e-134
 Identities = 243/485 (50%), Positives = 330/485 (68%), Gaps = 6/485 (1%)
 Frame = -3

Query: 1707 EYHHSFGLAAYNLRVTSAYA-RPIAIILPETKERLAATIVCCRKTSWAFTFRSGGHSLEG 1531
            +Y+     +  NLR     A +P+AI +P++ ++L  ++ CCR+  + F  R GGHS EG
Sbjct: 175  DYYRLLNFSLQNLRYAVPTAPKPVAIAIPQSLKQLVNSMRCCREGWYEFRVRCGGHSYEG 234

Query: 1530 LSYSAGNDHPFVMIDLMKLNQVVVDLESKTAWVEGGATLGEVYHAVGTLSNRLGFPAGYC 1351
            +S    + +PFV+ID+M LNQV VD+ES+TAWVEGGATLGE Y+AV   SN  GF AG C
Sbjct: 235  ISSVVPDGNPFVIIDMMSLNQVSVDVESETAWVEGGATLGETYYAVAEASNVHGFSAGSC 294

Query: 1350 PAVXXXXXXXXXXXGFMSRKYGLASDNVVDAILINADGQFLDRKSMGEDVFWAIRGGGAG 1171
            P V           G +SRKYGLA+DNVVDA+LI+ADG+ LDRK+MGEDVFWAIRGGG G
Sbjct: 295  PTVGVGGHIAGGGFGLLSRKYGLAADNVVDALLIDADGRVLDRKAMGEDVFWAIRGGGGG 354

Query: 1170 SWGAVYSWKIRLVDVPETVTALRVTRHGSRSEAVKLLNKWQWVAPDLEDEFTLMASVIA- 994
             WG VY+WKI+L+ VPETVT+  ++R  ++    +L++KWQ++AP LE  F L   V A 
Sbjct: 355  DWGIVYAWKIKLLKVPETVTSCIMSRTRTKLHVAELVHKWQFIAPRLEPSFYLSVFVGAG 414

Query: 993  ----ESETSILTIFQGLYLGLKSSAVASITQVFPELEVVASESKEMKWVESTAFFPDFTE 826
                + ET +   F+G YLG ++ A++ + +VFPEL V   + +EM W+ES  +F     
Sbjct: 415  LQGVDEETGVSASFKGFYLGSRNEAMSILNRVFPELGVEKEDCREMSWIESILYFSGLPN 474

Query: 825  RFTVDDLKDRFATSDQKAYFKWKGDYVRNNISIEGIEGMLDMLMKEPHGQLQLMPYGGMM 646
              ++ +L++R+   + K YFK K DYVR  IS+EG+   LD+L  EP G + L PYGG M
Sbjct: 475  GSSISELRNRYL--EDKLYFKAKSDYVRTPISMEGLVTALDILEMEPKGSVVLDPYGGEM 532

Query: 645  ARTRSDATPYPHREGNLYSIGYLVTWNEDDNKRSDIYMDWVHGIHEYMTPFVSKGPRAAY 466
             +  SDA P+PHR+GNL+SI Y+V W ED    S+ Y+DW+ G +++M P+VS+GPRAAY
Sbjct: 533  EKISSDALPFPHRKGNLFSIQYMVAWEEDSTAMSNKYIDWIRGFYKWMMPYVSQGPRAAY 592

Query: 465  VNELDLDLGVMDWGNHNISANELIELGRSWGEKYFLLNYERLVRAKTEIDPNNVFRHQQS 286
            VN +DLDLG M   N +IS+N+ +E  R WGEKYFL NY+RLV+ KT IDP+NVF +QQ 
Sbjct: 593  VNYMDLDLGQM---NSSISSNDPVEAARDWGEKYFLNNYDRLVKVKTCIDPDNVFNNQQG 649

Query: 285  IPPKP 271
            IPP P
Sbjct: 650  IPPMP 654


>gb|ACJ76783.1| berberine bridge enzyme 1 [Argemone mexicana]
          Length = 554

 Score =  486 bits (1250), Expect = e-134
 Identities = 247/502 (49%), Positives = 340/502 (67%), Gaps = 6/502 (1%)
 Frame = -3

Query: 1764 NFFSCISTEGV-NYTTPYAQ---EYHHSFGLAAYN-LRVTSAYARPIAIILPETKERLAA 1600
            +  SC+++ GV NYTTP +    +Y   + L+  N L   S  ++P  I+LP  KE L+ 
Sbjct: 38   DILSCLTSNGVHNYTTPSSDSNSDYLRLYHLSIQNPLFEKSTISKPSLIVLPRNKEELSN 97

Query: 1599 TIVCCRKTSWAFTFRSGGHSLEGLSYSAGNDHPFVMIDLMKLNQVVVDLESKTAWVEGGA 1420
            T+ CC + SW    RSGGHS EGLSY+A  D PFV+IDLM LN++ +D++S+TAWVE GA
Sbjct: 98   TVRCCTRGSWTIRLRSGGHSYEGLSYTA--DTPFVLIDLMNLNRISIDIDSETAWVESGA 155

Query: 1419 TLGEVYHAVGTLSNRLGFPAGYCPAVXXXXXXXXXXXGFMSRKYGLASDNVVDAILINAD 1240
            TLGE+Y+A+  L++ LGF AG+CP V           G MSRKYGLA+DNV D ILI++ 
Sbjct: 156  TLGELYYAITELTDSLGFTAGWCPTVGSGGHISGGGFGMMSRKYGLAADNVEDVILIDSK 215

Query: 1239 GQFLDRKSMGEDVFWAIRGGGAGSWGAVYSWKIRLVDVPETVTALRVTRHGSRSEAVKLL 1060
            G  LDRK MGEDVFWA+RGGG G WGA+Y+WKI+L+ VP+ VT  RVT++ +  EA  L+
Sbjct: 216  GAILDRKLMGEDVFWAVRGGGGGVWGAIYAWKIKLLPVPKKVTVFRVTKNVNIEEASFLI 275

Query: 1059 NKWQWVAPDLEDEFTLMASVIAESE-TSILTIFQGLYLGLKSSAVASITQVFPELEVVAS 883
            +KWQ+VA +L+D+FT+  S++  +    +  IF GL+LG K+ A + I + FPEL ++  
Sbjct: 276  HKWQYVADELDDDFTV--SILGGANGNEVWVIFLGLHLGCKTVAKSIIDKKFPELGLIEE 333

Query: 882  ESKEMKWVESTAFFPDFTERFTVDDLKDRFATSDQKAYFKWKGDYVRNNISIEGIEGMLD 703
            E  EM W ES A+        TV +L +RF   D +A FK K D+ +  + +E I+G+L+
Sbjct: 334  EFLEMNWGESFAYLSGLK---TVKELNNRFLKFDDRA-FKTKVDFTKETLPLEAIDGLLE 389

Query: 702  MLMKEPHGQLQLMPYGGMMARTRSDATPYPHREGNLYSIGYLVTWNEDDNKRSDIYMDWV 523
            +L KEP G + L  +GG M++  +D TP+PHR+G    + Y+V W++D+  +SD + DW+
Sbjct: 390  ILSKEPRGFIALNGFGGKMSKISNDFTPFPHRKGTKLMVEYIVAWSKDEESKSDEFFDWL 449

Query: 522  HGIHEYMTPFVSKGPRAAYVNELDLDLGVMDWGNHNISANELIELGRSWGEKYFLLNYER 343
              I++YM  FVSK PR  YVN +DLDLG +DW + N S+N  IE+ R+WGEKYFL NYER
Sbjct: 450  RNIYDYMEMFVSKNPRVGYVNHIDLDLGGIDWSDKN-SSNNAIEIARNWGEKYFLSNYER 508

Query: 342  LVRAKTEIDPNNVFRHQQSIPP 277
            L+RAKT IDPNNVF H QSIPP
Sbjct: 509  LIRAKTLIDPNNVFNHPQSIPP 530


>ref|XP_007099511.1| FAD-binding Berberine family protein [Theobroma cacao]
            gi|508728622|gb|EOY20519.1| FAD-binding Berberine family
            protein [Theobroma cacao]
          Length = 875

 Score =  485 bits (1248), Expect = e-134
 Identities = 250/534 (46%), Positives = 342/534 (64%), Gaps = 12/534 (2%)
 Frame = -3

Query: 1755 SCISTEGVNYTTPYAQE-------YHHSFGLAAYNLRVTSAY-ARPIAIILPETKERLAA 1600
            SC++   +N  T ++         Y++    +  NLR   A   +PIAIILPE+KE+L  
Sbjct: 73   SCLNRHNINNYTTFSNLENNESSLYYNLLNFSIQNLRFAEATNPKPIAIILPESKEQLIN 132

Query: 1599 TIVCCRKTSWAFTFRSGGHSLEGLSYSAGNDHPFVMIDLMKLNQVVVDLESKTAWVEGGA 1420
            +++CC    W    R GGH+ EG S  A +  PFV+ID+M LN V VDLES+TAWVEGGA
Sbjct: 133  SVLCCIAGPWEIRVRCGGHNYEGTSSVASDGAPFVIIDMMNLNLVSVDLESETAWVEGGA 192

Query: 1419 TLGEVYHAVGTLSNRLGFPAGYCPAVXXXXXXXXXXXGFMSRKYGLASDNVVDAILINAD 1240
            TLGE YHA+   S    F AG CP V           GF+SRKYGLA+DNV+DA+L+NAD
Sbjct: 193  TLGETYHAIAESSRIHAFSAGSCPTVGAGGHIGGGGFGFLSRKYGLAADNVIDALLLNAD 252

Query: 1239 GQFLDRKSMGEDVFWAIRGGGAGSWGAVYSWKIRLVDVPETVTALRVTRHGSRSEAVKLL 1060
            G+ LDR++MGEDVFWAIRGGG G WG VY+WK+ L+ VP+TVT+  V+R G++++  KL+
Sbjct: 253  GEILDRQAMGEDVFWAIRGGGGGFWGIVYAWKVNLLKVPQTVTSFIVSRPGTKAQVAKLV 312

Query: 1059 NKWQWVAPDLEDEFTLMASVIAE-SETSILTI---FQGLYLGLKSSAVASITQVFPELEV 892
            NKWQ VAP+ E +  L   V A   ET  + +   F+G +LG +  A++ + + FP+L V
Sbjct: 313  NKWQHVAPNFEGDLYLSCFVGAGLPETKAMGLSATFKGFFLGPRREALSILRRSFPQLGV 372

Query: 891  VASESKEMKWVESTAFFPDFTERFTVDDLKDRFATSDQKAYFKWKGDYVRNNISIEGIEG 712
               + KE  W++S  FF    +  TV DLK+R+     K YFK K DYVRN IS+ GI  
Sbjct: 373  AEEDCKETSWIDSVLFFSGLADGATVSDLKNRYL--QDKHYFKAKSDYVRNPISLTGIRA 430

Query: 711  MLDMLMKEPHGQLQLMPYGGMMARTRSDATPYPHREGNLYSIGYLVTWNEDDNKRSDIYM 532
             LD+L KEP G + L PYGG+M    SD+  +PHR+GNLY+I YLV W+E D  + + Y+
Sbjct: 431  ALDILDKEPKGYVVLDPYGGIMNNISSDSIAFPHRQGNLYTIQYLVEWHEVDGNKGNEYI 490

Query: 531  DWVHGIHEYMTPFVSKGPRAAYVNELDLDLGVMDWGNHNISANELIELGRSWGEKYFLLN 352
            +W+ G +  M  +VS GPRAAY+N +D D+GVM+  N ++ + + +E+ R WGEKYFL N
Sbjct: 491  EWIRGFYTAMAGYVSWGPRAAYINYMDFDIGVMELINTSVPSYDTVEIARVWGEKYFLNN 550

Query: 351  YERLVRAKTEIDPNNVFRHQQSIPPKPLQGSCPAEGINQFRRS*RLAFLPIAIL 190
            Y+RLV+AKT IDPNN+F++QQ IPP     S P +      R+ R +   + IL
Sbjct: 551  YDRLVKAKTLIDPNNIFKNQQGIPPATSVVSPPIKARKLHPRTNRQSASKVCIL 604


>ref|XP_003535410.1| PREDICTED: reticuline oxidase-like [Glycine max]
          Length = 550

 Score =  484 bits (1246), Expect = e-134
 Identities = 244/507 (48%), Positives = 332/507 (65%), Gaps = 14/507 (2%)
 Frame = -3

Query: 1755 SCISTEGV-NYTTPYAQEYHHSFGLAAY--------NLRVTS-AYARPIAIILPETKERL 1606
            SC+    + N+TT   +E+ HS     Y        NLR       +PIAI+LPE+ E+L
Sbjct: 33   SCLDNHDIKNFTTLPYKEHDHSSAYNYYKILNFSIQNLRFAEPVIPKPIAIVLPESLEQL 92

Query: 1605 AATIVCCRKTSWAFTFRSGGHSLEGLSYSAGNDHPFVMIDLMKLNQVVVDLESKTAWVEG 1426
              ++ CCR+       R GGHS EG SY A +  PFV+ID+M LN V VD+E++TAWVEG
Sbjct: 93   QKSVACCREGFMEIRVRCGGHSYEGTSYVADDGTPFVIIDMMNLNHVWVDMETETAWVEG 152

Query: 1425 GATLGEVYHAVGTLSNRLGFPAGYCPAVXXXXXXXXXXXGFMSRKYGLASDNVVDAILIN 1246
            GATLGE Y+A+   SN  GF  G CP V           G +SRKYGLA+DNVVDA+L+N
Sbjct: 153  GATLGETYYAISQASNEHGFSGGSCPTVGVGGHIGGGGFGILSRKYGLAADNVVDALLVN 212

Query: 1245 ADGQFLDRKSMGEDVFWAIRGGGAGSWGAVYSWKIRLVDVPETVTALRVTRHGSRSEAVK 1066
            ADG+  DR++MGEDVFWAIRGGG G WG +Y+WKI+++ +P+ VT+  V+R G++     
Sbjct: 213  ADGKLFDRETMGEDVFWAIRGGGGGLWGIIYAWKIKVLKLPQVVTSFTVSRTGTKRHVAN 272

Query: 1065 LLNKWQWVAPDLEDEFTLMASV---IAESET-SILTIFQGLYLGLKSSAVASITQVFPEL 898
            L++KWQ VAP+LED+F L   V   + +++T  + T F G YLG ++ A++ +   FPEL
Sbjct: 273  LVHKWQNVAPNLEDDFYLSCFVGAGLPQAKTKGLSTTFNGFYLGPRAGAISILDHAFPEL 332

Query: 897  EVVASESKEMKWVESTAFFPDFTERFTVDDLKDRFATSDQKAYFKWKGDYVRNNISIEGI 718
             +V  E  EM W++ST FF   ++  +V DL +R+    +K YFK K DYV+ ++ + GI
Sbjct: 333  GIVEEECIEMSWIQSTVFFSGLSDGASVSDLNNRYL--QEKQYFKAKSDYVKKHVPLVGI 390

Query: 717  EGMLDMLMKEPHGQLQLMPYGGMMARTRSDATPYPHREGNLYSIGYLVTWNEDDNKRSDI 538
            E  LD+L KEP G + L PYGG M    S++  +PHR GNL++I YL+ W E DN ++  
Sbjct: 391  ETALDILEKEPKGYVILDPYGGKMHNISSESIAFPHRRGNLFTIQYLIYWKEADNDKNSD 450

Query: 537  YMDWVHGIHEYMTPFVSKGPRAAYVNELDLDLGVMDWGNHNISANELIELGRSWGEKYFL 358
            Y+DW+ G +  MTPFVS GPRAAYVN +D DLGVM+  ++  +  +++E  R WGEKYFL
Sbjct: 451  YVDWIRGFYAAMTPFVSWGPRAAYVNYMDFDLGVMERISNGANMKDVVEHARVWGEKYFL 510

Query: 357  LNYERLVRAKTEIDPNNVFRHQQSIPP 277
             NY+RLVRAKT IDPNNVF + Q IPP
Sbjct: 511  SNYDRLVRAKTLIDPNNVFTNDQGIPP 537


>ref|XP_002533924.1| d-lactate dehydrogenase, putative [Ricinus communis]
            gi|223526119|gb|EEF28466.1| d-lactate dehydrogenase,
            putative [Ricinus communis]
          Length = 546

 Score =  484 bits (1246), Expect = e-134
 Identities = 247/510 (48%), Positives = 329/510 (64%), Gaps = 11/510 (2%)
 Frame = -3

Query: 1761 FFSCISTEGVNYTTPY------AQEYHHSFGLAAYNLRVTSA-YARPIAIILPETKERLA 1603
            F SC++   ++  T +      + +Y++    +  NLR       +P+AI++PET E L 
Sbjct: 31   FTSCLTQNLISNFTTFPSSKNDSTDYYNLLEFSIQNLRFADLEMPKPLAIVIPETVEELV 90

Query: 1602 ATIVCCRKTSWAFTFRSGGHSLEGLSYSAGNDHPFVMIDLMKLNQVVVDLESKTAWVEGG 1423
             T+ CCR+       R GGHS EG SY A +   FV+ID+M LN+V VDLE+K A VEGG
Sbjct: 91   KTVTCCREAFLEIRVRCGGHSYEGTSYVASDGATFVVIDMMNLNKVSVDLEAKMAVVEGG 150

Query: 1422 ATLGEVYHAVGTLSNRLGFPAGYCPAVXXXXXXXXXXXGFMSRKYGLASDNVVDAILINA 1243
            ATLGE Y A+   S   GF AG CP V           G +SRKYGLA+DNVVDA+L++A
Sbjct: 151  ATLGETYAAIAEASGVHGFSAGSCPTVGVGGHIGGGGFGLLSRKYGLAADNVVDALLVDA 210

Query: 1242 DGQFLDRKSMGEDVFWAIRGGGAGSWGAVYSWKIRLVDVPETVTALRVTRHGSRSEAVKL 1063
            +G+ LDRK MGEDVFWAIRGGG G WG +Y+WKI+L+ VP  VT   V+R G++    KL
Sbjct: 211  NGRLLDRKEMGEDVFWAIRGGGGGVWGILYAWKIKLLKVPRVVTGFIVSRPGTKGHVAKL 270

Query: 1062 LNKWQWVAPDLEDEFTLMASVIA----ESETSILTIFQGLYLGLKSSAVASITQVFPELE 895
            +NKWQ VAP L+D+F L   V A       T I   F+G YLG +S AV+ + + FPEL 
Sbjct: 271  VNKWQHVAPGLDDDFYLSCFVGAGLPEAKTTGISATFKGFYLGPRSEAVSILNKNFPELG 330

Query: 894  VVASESKEMKWVESTAFFPDFTERFTVDDLKDRFATSDQKAYFKWKGDYVRNNISIEGIE 715
            +V  + KEM W+ES  FF   +   TV DLK+R      K+YFK K DYV++ IS  GI+
Sbjct: 331  IVEEDCKEMSWIESVLFFSGLSNGSTVSDLKNRHLQG--KSYFKAKSDYVKSEISSAGIK 388

Query: 714  GMLDMLMKEPHGQLQLMPYGGMMARTRSDATPYPHREGNLYSIGYLVTWNEDDNKRSDIY 535
              LD+L KEP G + L PYGG+M    S+A  +PHR GNL++I YLV W E D  +S++Y
Sbjct: 389  IALDILQKEPKGYVILDPYGGVMHNISSEAIAFPHRNGNLFTIQYLVEWKEKDKNKSNVY 448

Query: 534  MDWVHGIHEYMTPFVSKGPRAAYVNELDLDLGVMDWGNHNISANELIELGRSWGEKYFLL 355
            +DW+   +  MTPFVS+GPRAAY+N +D D+G M     ++ + + +E+ R WGEKYFL 
Sbjct: 449  IDWIREFYYLMTPFVSRGPRAAYINYMDFDIGAMGMIKKSVPSEDAVEIARVWGEKYFLR 508

Query: 354  NYERLVRAKTEIDPNNVFRHQQSIPPKPLQ 265
            N++RLVRAKT IDP+NVF ++QSIPP PL+
Sbjct: 509  NFDRLVRAKTLIDPDNVFNNEQSIPPLPLE 538


>ref|XP_006371334.1| hypothetical protein POPTR_0019s09180g [Populus trichocarpa]
            gi|550317087|gb|ERP49131.1| hypothetical protein
            POPTR_0019s09180g [Populus trichocarpa]
          Length = 551

 Score =  483 bits (1242), Expect = e-133
 Identities = 253/521 (48%), Positives = 336/521 (64%), Gaps = 16/521 (3%)
 Frame = -3

Query: 1791 SITGREDDFNFFSCISTEGVNYTTPY--------AQEYHHSFGLAAYNLRVTS-AYARPI 1639
            S+   ED     SC++T  +N  T          ++ Y+     +  NLR T    A+P+
Sbjct: 23   SLCAPEDQIT--SCLTTHDINNFTTLPSTKKDDDSKTYYKILDFSIQNLRFTEPTIAKPL 80

Query: 1638 AIILPETKERLAATIVCCRKTSWAFTFRSGGHSLEGLSYSAGNDHPFVMIDLMKLNQVVV 1459
            AIILPE+ + L  +++CCR+       R GGHS EG S  A +  PFV+ID+M LN+V V
Sbjct: 81   AIILPESLDELVKSVMCCREGLLEIRVRCGGHSYEGTSSVANDGAPFVIIDMMNLNKVSV 140

Query: 1458 DLESKTAWVEGGATLGEVYHAVGTLSNRLGFPAGYCPAVXXXXXXXXXXXGFMSRKYGLA 1279
             LE++TAWVEGGATLGE Y A+   S+  GF AG CP V           G +SRKYGLA
Sbjct: 141  HLETETAWVEGGATLGETYSAISEASSIHGFSAGSCPTVGVGGHIGGGGFGLLSRKYGLA 200

Query: 1278 SDNVVDAILINADGQFLDRKSMGEDVFWAIRGGGAGSWGAVYSWKIRLVDVPETVTALRV 1099
            +DNVVDA+LI+A+G+ LDRK+M EDVFWAIRGGG G+WG +Y+WKIRL+ VPE VT   V
Sbjct: 201  ADNVVDALLIDANGRLLDRKAMEEDVFWAIRGGGGGAWGIIYAWKIRLLKVPEVVTGFIV 260

Query: 1098 TRHGSRSEAVKLLNKWQWVAPDLEDEFTLM----ASVIAESETSILTIFQGLYLGLKSSA 931
            +R G++ +  +L+N WQ VAP ++ +F L     A +       I   F+G YLG ++ A
Sbjct: 261  SRPGTKYQVAELVNGWQGVAPSMDGDFYLSCFVGAGLPGTKTRGISATFKGFYLGPRNEA 320

Query: 930  VASITQVFPELEVVASESKEMKWVESTAFFPDFTERFTVDDLKDRFATSDQKAYFKWKGD 751
            V+ + QVFPEL +   + KEM W+ES  FF   ++   V DLK+R+  +++K YFK K D
Sbjct: 321  VSILNQVFPELGIETEDCKEMTWIESILFFSGLSDGSLVSDLKNRY--TEEKNYFKAKSD 378

Query: 750  YVRNNISIEGIEGMLDMLMKEPHGQLQLMPYGGMMARTRSDATPYPHREGNLYSIGYLVT 571
            YVR NIS EGI   LD+L KEP G + L PYGG+M    SDA  +PHREGNL++I YLV 
Sbjct: 379  YVRRNISFEGIRTALDILEKEPKGYVILDPYGGIMQNISSDAIAFPHREGNLFTIQYLVE 438

Query: 570  WNEDDNKRSDIYMDWVHGIHEYMTPFVSKGPRAAYVNELDLDLGVMDWGNHNIS---ANE 400
            W E D+ +S+ Y++W+   +  MTPFVS GPRAAY+N +D DLGVM+  +   S   A +
Sbjct: 439  WKERDDNKSNDYINWIRKFYNAMTPFVSFGPRAAYINYMDFDLGVMELLHDKTSMVPARD 498

Query: 399  LIELGRSWGEKYFLLNYERLVRAKTEIDPNNVFRHQQSIPP 277
             +E+ R WGEKYFL NY+RLV  KT IDP+NVF +QQSIPP
Sbjct: 499  AVEVARVWGEKYFLRNYDRLVEVKTYIDPDNVFSNQQSIPP 539


>sp|P30986.1|RETO_ESCCA RecName: Full=Reticuline oxidase; AltName: Full=Berberine
            bridge-forming enzyme; Short=BBE; AltName:
            Full=Tetrahydroprotoberberine synthase; Flags: Precursor
            gi|239110|gb|AAB20352.1| (S)-reticuline:oxygen
            oxidoreductase (methylene-bridge-forming) [Eschscholzia
            californica] gi|2897944|gb|AAC39358.1| berberine bridge
            enzyme [Eschscholzia californica]
          Length = 538

 Score =  479 bits (1234), Expect = e-132
 Identities = 249/501 (49%), Positives = 332/501 (66%), Gaps = 5/501 (0%)
 Frame = -3

Query: 1764 NFFSCISTEGVNYTTPYAQEYHHSFG----LAAYN-LRVTSAYARPIAIILPETKERLAA 1600
            +  SC++  GV   T ++ +    F     L+  N L   S  ++P AIILP +KE L+ 
Sbjct: 26   DLLSCLTFNGVRNHTVFSADSDSDFNRFLHLSIQNPLFQNSLISKPSAIILPGSKEELSN 85

Query: 1599 TIVCCRKTSWAFTFRSGGHSLEGLSYSAGNDHPFVMIDLMKLNQVVVDLESKTAWVEGGA 1420
            TI C RK SW    RSGGHS EGLSY++  D PF++IDLM LN+V +DLES+TAWVE G+
Sbjct: 86   TIRCIRKGSWTIRLRSGGHSYEGLSYTS--DTPFILIDLMNLNRVSIDLESETAWVESGS 143

Query: 1419 TLGEVYHAVGTLSNRLGFPAGYCPAVXXXXXXXXXXXGFMSRKYGLASDNVVDAILINAD 1240
            TLGE+Y+A+   S++LGF AG+CP V           G MSRKYGLA+DNVVDAILI+A+
Sbjct: 144  TLGELYYAITESSSKLGFTAGWCPTVGTGGHISGGGFGMMSRKYGLAADNVVDAILIDAN 203

Query: 1239 GQFLDRKSMGEDVFWAIRGGGAGSWGAVYSWKIRLVDVPETVTALRVTRHGSRSEAVKLL 1060
            G  LDR++MGEDVFWAIRGGG G WGA+Y+WKI+L+ VPE VT  RVT++ +  EA  LL
Sbjct: 204  GAILDRQAMGEDVFWAIRGGGGGVWGAIYAWKIKLLPVPEKVTVFRVTKNVAIDEATSLL 263

Query: 1059 NKWQWVAPDLEDEFTLMASVIAESETSILTIFQGLYLGLKSSAVASITQVFPELEVVASE 880
            +KWQ+VA +LE++FTL     A+ +   LT+  G + GLK+ A ++   +FPEL +V  +
Sbjct: 264  HKWQFVAEELEEDFTLSVLGGADEKQVWLTML-GFHFGLKTVAKSTFDLLFPELGLVEED 322

Query: 879  SKEMKWVESTAFFPDFTERFTVDDLKDRFATSDQKAYFKWKGDYVRNNISIEGIEGMLDM 700
              EM W ES A+        TV  L +RF   D++A FK K D  +  +  +   G+L+ 
Sbjct: 323  YLEMSWGESFAYLAGLE---TVSQLNNRFLKFDERA-FKTKVDLTKEPLPSKAFYGLLER 378

Query: 699  LMKEPHGQLQLMPYGGMMARTRSDATPYPHREGNLYSIGYLVTWNEDDNKRSDIYMDWVH 520
            L KEP+G + L  +GG M++  SD TP+PHR G    + Y+V WN+ + K+   ++DW+ 
Sbjct: 379  LSKEPNGFIALNGFGGQMSKISSDFTPFPHRSGTRLMVEYIVAWNQSEQKKKTEFLDWLE 438

Query: 519  GIHEYMTPFVSKGPRAAYVNELDLDLGVMDWGNHNISANELIELGRSWGEKYFLLNYERL 340
             ++E+M PFVSK PR  YVN +DLDLG +DWGN  +  N  IE+ RSWGE YFL NYERL
Sbjct: 439  KVYEFMKPFVSKNPRLGYVNHIDLDLGGIDWGNKTV-VNNAIEISRSWGESYFLSNYERL 497

Query: 339  VRAKTEIDPNNVFRHQQSIPP 277
            +RAKT IDPNNVF H QSIPP
Sbjct: 498  IRAKTLIDPNNVFNHPQSIPP 518


>pdb|4EC3|A Chain A, Structure Of Berberine Bridge Enzyme, H174a Variant In
            Complex With (S)-Reticuline
          Length = 519

 Score =  479 bits (1234), Expect = e-132
 Identities = 249/501 (49%), Positives = 332/501 (66%), Gaps = 5/501 (0%)
 Frame = -3

Query: 1764 NFFSCISTEGVNYTTPYAQEYHHSFG----LAAYN-LRVTSAYARPIAIILPETKERLAA 1600
            +  SC++  GV   T ++ +    F     L+  N L   S  ++P AIILP +KE L+ 
Sbjct: 7    DLLSCLTFNGVRNHTVFSADSDSDFNRFLHLSIQNPLFQNSLISKPSAIILPGSKEELSN 66

Query: 1599 TIVCCRKTSWAFTFRSGGHSLEGLSYSAGNDHPFVMIDLMKLNQVVVDLESKTAWVEGGA 1420
            TI C RK SW    RSGGHS EGLSY++  D PF++IDLM LN+V +DLES+TAWVE G+
Sbjct: 67   TIRCIRKGSWTIRLRSGGHSYEGLSYTS--DTPFILIDLMNLNRVSIDLESETAWVESGS 124

Query: 1419 TLGEVYHAVGTLSNRLGFPAGYCPAVXXXXXXXXXXXGFMSRKYGLASDNVVDAILINAD 1240
            TLGE+Y+A+   S++LGF AG+CP V           G MSRKYGLA+DNVVDAILI+A+
Sbjct: 125  TLGELYYAITESSSKLGFTAGWCPTVGTGGAISGGGFGMMSRKYGLAADNVVDAILIDAN 184

Query: 1239 GQFLDRKSMGEDVFWAIRGGGAGSWGAVYSWKIRLVDVPETVTALRVTRHGSRSEAVKLL 1060
            G  LDR++MGEDVFWAIRGGG G WGA+Y+WKI+L+ VPE VT  RVT++ +  EA  LL
Sbjct: 185  GAILDRQAMGEDVFWAIRGGGGGVWGAIYAWKIKLLPVPEKVTVFRVTKNVAIDEATSLL 244

Query: 1059 NKWQWVAPDLEDEFTLMASVIAESETSILTIFQGLYLGLKSSAVASITQVFPELEVVASE 880
            +KWQ+VA +LE++FTL     A+ +   LT+  G + GLK+ A ++   +FPEL +V  +
Sbjct: 245  HKWQFVAEELEEDFTLSVLGGADEKQVWLTML-GFHFGLKTVAKSTFDLLFPELGLVEED 303

Query: 879  SKEMKWVESTAFFPDFTERFTVDDLKDRFATSDQKAYFKWKGDYVRNNISIEGIEGMLDM 700
              EM W ES A+        TV  L +RF   D++A FK K D  +  +  +   G+L+ 
Sbjct: 304  YLEMSWGESFAYLAGLE---TVSQLNNRFLKFDERA-FKTKVDLTKEPLPSKAFYGLLER 359

Query: 699  LMKEPHGQLQLMPYGGMMARTRSDATPYPHREGNLYSIGYLVTWNEDDNKRSDIYMDWVH 520
            L KEP+G + L  +GG M++  SD TP+PHR G    + Y+V WN+ + K+   ++DW+ 
Sbjct: 360  LSKEPNGFIALNGFGGQMSKISSDFTPFPHRSGTRLMVEYIVAWNQSEQKKKTEFLDWLE 419

Query: 519  GIHEYMTPFVSKGPRAAYVNELDLDLGVMDWGNHNISANELIELGRSWGEKYFLLNYERL 340
             ++E+M PFVSK PR  YVN +DLDLG +DWGN  +  N  IE+ RSWGE YFL NYERL
Sbjct: 420  KVYEFMKPFVSKNPRLGYVNHIDLDLGGIDWGNKTV-VNNAIEISRSWGESYFLSNYERL 478

Query: 339  VRAKTEIDPNNVFRHQQSIPP 277
            +RAKT IDPNNVF H QSIPP
Sbjct: 479  IRAKTLIDPNNVFNHPQSIPP 499


>pdb|3GSY|A Chain A, Structure Of Berberine Bridge Enzyme In Complex With
            Dehydroscoulerine
          Length = 519

 Score =  479 bits (1234), Expect = e-132
 Identities = 249/501 (49%), Positives = 332/501 (66%), Gaps = 5/501 (0%)
 Frame = -3

Query: 1764 NFFSCISTEGVNYTTPYAQEYHHSFG----LAAYN-LRVTSAYARPIAIILPETKERLAA 1600
            +  SC++  GV   T ++ +    F     L+  N L   S  ++P AIILP +KE L+ 
Sbjct: 7    DLLSCLTFNGVRNHTVFSADSDSDFNRFLHLSIQNPLFQNSLISKPSAIILPGSKEELSN 66

Query: 1599 TIVCCRKTSWAFTFRSGGHSLEGLSYSAGNDHPFVMIDLMKLNQVVVDLESKTAWVEGGA 1420
            TI C RK SW    RSGGHS EGLSY++  D PF++IDLM LN+V +DLES+TAWVE G+
Sbjct: 67   TIRCIRKGSWTIRLRSGGHSYEGLSYTS--DTPFILIDLMNLNRVSIDLESETAWVESGS 124

Query: 1419 TLGEVYHAVGTLSNRLGFPAGYCPAVXXXXXXXXXXXGFMSRKYGLASDNVVDAILINAD 1240
            TLGE+Y+A+   S++LGF AG+CP V           G MSRKYGLA+DNVVDAILI+A+
Sbjct: 125  TLGELYYAITESSSKLGFTAGWCPTVGTGGHISGGGFGMMSRKYGLAADNVVDAILIDAN 184

Query: 1239 GQFLDRKSMGEDVFWAIRGGGAGSWGAVYSWKIRLVDVPETVTALRVTRHGSRSEAVKLL 1060
            G  LDR++MGEDVFWAIRGGG G WGA+Y+WKI+L+ VPE VT  RVT++ +  EA  LL
Sbjct: 185  GAILDRQAMGEDVFWAIRGGGGGVWGAIYAWKIKLLPVPEKVTVFRVTKNVAIDEATSLL 244

Query: 1059 NKWQWVAPDLEDEFTLMASVIAESETSILTIFQGLYLGLKSSAVASITQVFPELEVVASE 880
            +KWQ+VA +LE++FTL     A+ +   LT+  G + GLK+ A ++   +FPEL +V  +
Sbjct: 245  HKWQFVAEELEEDFTLSVLGGADEKQVWLTML-GFHFGLKTVAKSTFDLLFPELGLVEED 303

Query: 879  SKEMKWVESTAFFPDFTERFTVDDLKDRFATSDQKAYFKWKGDYVRNNISIEGIEGMLDM 700
              EM W ES A+        TV  L +RF   D++A FK K D  +  +  +   G+L+ 
Sbjct: 304  YLEMSWGESFAYLAGLE---TVSQLNNRFLKFDERA-FKTKVDLTKEPLPSKAFYGLLER 359

Query: 699  LMKEPHGQLQLMPYGGMMARTRSDATPYPHREGNLYSIGYLVTWNEDDNKRSDIYMDWVH 520
            L KEP+G + L  +GG M++  SD TP+PHR G    + Y+V WN+ + K+   ++DW+ 
Sbjct: 360  LSKEPNGFIALNGFGGQMSKISSDFTPFPHRSGTRLMVEYIVAWNQSEQKKKTEFLDWLE 419

Query: 519  GIHEYMTPFVSKGPRAAYVNELDLDLGVMDWGNHNISANELIELGRSWGEKYFLLNYERL 340
             ++E+M PFVSK PR  YVN +DLDLG +DWGN  +  N  IE+ RSWGE YFL NYERL
Sbjct: 420  KVYEFMKPFVSKNPRLGYVNHIDLDLGGIDWGNKTV-VNNAIEISRSWGESYFLSNYERL 478

Query: 339  VRAKTEIDPNNVFRHQQSIPP 277
            +RAKT IDPNNVF H QSIPP
Sbjct: 479  IRAKTLIDPNNVFNHPQSIPP 499


>pdb|3FW9|A Chain A, Structure Of Berberine Bridge Enzyme In Complex With
            (S)-Scoulerine
          Length = 495

 Score =  479 bits (1234), Expect = e-132
 Identities = 249/501 (49%), Positives = 332/501 (66%), Gaps = 5/501 (0%)
 Frame = -3

Query: 1764 NFFSCISTEGVNYTTPYAQEYHHSFG----LAAYN-LRVTSAYARPIAIILPETKERLAA 1600
            +  SC++  GV   T ++ +    F     L+  N L   S  ++P AIILP +KE L+ 
Sbjct: 1    DLLSCLTFNGVRNHTVFSADSDSDFNRFLHLSIQNPLFQNSLISKPSAIILPGSKEELSN 60

Query: 1599 TIVCCRKTSWAFTFRSGGHSLEGLSYSAGNDHPFVMIDLMKLNQVVVDLESKTAWVEGGA 1420
            TI C RK SW    RSGGHS EGLSY++  D PF++IDLM LN+V +DLES+TAWVE G+
Sbjct: 61   TIRCIRKGSWTIRLRSGGHSYEGLSYTS--DTPFILIDLMNLNRVSIDLESETAWVESGS 118

Query: 1419 TLGEVYHAVGTLSNRLGFPAGYCPAVXXXXXXXXXXXGFMSRKYGLASDNVVDAILINAD 1240
            TLGE+Y+A+   S++LGF AG+CP V           G MSRKYGLA+DNVVDAILI+A+
Sbjct: 119  TLGELYYAITESSSKLGFTAGWCPTVGTGGHISGGGFGMMSRKYGLAADNVVDAILIDAN 178

Query: 1239 GQFLDRKSMGEDVFWAIRGGGAGSWGAVYSWKIRLVDVPETVTALRVTRHGSRSEAVKLL 1060
            G  LDR++MGEDVFWAIRGGG G WGA+Y+WKI+L+ VPE VT  RVT++ +  EA  LL
Sbjct: 179  GAILDRQAMGEDVFWAIRGGGGGVWGAIYAWKIKLLPVPEKVTVFRVTKNVAIDEATSLL 238

Query: 1059 NKWQWVAPDLEDEFTLMASVIAESETSILTIFQGLYLGLKSSAVASITQVFPELEVVASE 880
            +KWQ+VA +LE++FTL     A+ +   LT+  G + GLK+ A ++   +FPEL +V  +
Sbjct: 239  HKWQFVAEELEEDFTLSVLGGADEKQVWLTML-GFHFGLKTVAKSTFDLLFPELGLVEED 297

Query: 879  SKEMKWVESTAFFPDFTERFTVDDLKDRFATSDQKAYFKWKGDYVRNNISIEGIEGMLDM 700
              EM W ES A+        TV  L +RF   D++A FK K D  +  +  +   G+L+ 
Sbjct: 298  YLEMSWGESFAYLAGLE---TVSQLNNRFLKFDERA-FKTKVDLTKEPLPSKAFYGLLER 353

Query: 699  LMKEPHGQLQLMPYGGMMARTRSDATPYPHREGNLYSIGYLVTWNEDDNKRSDIYMDWVH 520
            L KEP+G + L  +GG M++  SD TP+PHR G    + Y+V WN+ + K+   ++DW+ 
Sbjct: 354  LSKEPNGFIALNGFGGQMSKISSDFTPFPHRSGTRLMVEYIVAWNQSEQKKKTEFLDWLE 413

Query: 519  GIHEYMTPFVSKGPRAAYVNELDLDLGVMDWGNHNISANELIELGRSWGEKYFLLNYERL 340
             ++E+M PFVSK PR  YVN +DLDLG +DWGN  +  N  IE+ RSWGE YFL NYERL
Sbjct: 414  KVYEFMKPFVSKNPRLGYVNHIDLDLGGIDWGNKTV-VNNAIEISRSWGESYFLSNYERL 472

Query: 339  VRAKTEIDPNNVFRHQQSIPP 277
            +RAKT IDPNNVF H QSIPP
Sbjct: 473  IRAKTLIDPNNVFNHPQSIPP 493


>pdb|3D2D|A Chain A, Structure Of Berberine Bridge Enzyme In Complex With
            (S)-Reticuline gi|210060956|pdb|3D2H|A Chain A, Structure
            Of Berberine Bridge Enzyme From Eschscholzia Californica,
            Monoclinic Crystal Form gi|210060957|pdb|3D2J|A Chain A,
            Structure Of Berberine Bridge Enzyme From Eschscholzia
            Californica, Tetragonal Crystal Form
          Length = 538

 Score =  479 bits (1234), Expect = e-132
 Identities = 249/501 (49%), Positives = 332/501 (66%), Gaps = 5/501 (0%)
 Frame = -3

Query: 1764 NFFSCISTEGVNYTTPYAQEYHHSFG----LAAYN-LRVTSAYARPIAIILPETKERLAA 1600
            +  SC++  GV   T ++ +    F     L+  N L   S  ++P AIILP +KE L+ 
Sbjct: 26   DLLSCLTFNGVRNHTVFSADSDSDFNRFLHLSIQNPLFQNSLISKPSAIILPGSKEELSN 85

Query: 1599 TIVCCRKTSWAFTFRSGGHSLEGLSYSAGNDHPFVMIDLMKLNQVVVDLESKTAWVEGGA 1420
            TI C RK SW    RSGGHS EGLSY++  D PF++IDLM LN+V +DLES+TAWVE G+
Sbjct: 86   TIRCIRKGSWTIRLRSGGHSYEGLSYTS--DTPFILIDLMNLNRVSIDLESETAWVESGS 143

Query: 1419 TLGEVYHAVGTLSNRLGFPAGYCPAVXXXXXXXXXXXGFMSRKYGLASDNVVDAILINAD 1240
            TLGE+Y+A+   S++LGF AG+CP V           G MSRKYGLA+DNVVDAILI+A+
Sbjct: 144  TLGELYYAITESSSKLGFTAGWCPTVGTGGHISGGGFGMMSRKYGLAADNVVDAILIDAN 203

Query: 1239 GQFLDRKSMGEDVFWAIRGGGAGSWGAVYSWKIRLVDVPETVTALRVTRHGSRSEAVKLL 1060
            G  LDR++MGEDVFWAIRGGG G WGA+Y+WKI+L+ VPE VT  RVT++ +  EA  LL
Sbjct: 204  GAILDRQAMGEDVFWAIRGGGGGVWGAIYAWKIKLLPVPEKVTVFRVTKNVAIDEATSLL 263

Query: 1059 NKWQWVAPDLEDEFTLMASVIAESETSILTIFQGLYLGLKSSAVASITQVFPELEVVASE 880
            +KWQ+VA +LE++FTL     A+ +   LT+  G + GLK+ A ++   +FPEL +V  +
Sbjct: 264  HKWQFVAEELEEDFTLSVLGGADEKQVWLTML-GFHFGLKTVAKSTFDLLFPELGLVEED 322

Query: 879  SKEMKWVESTAFFPDFTERFTVDDLKDRFATSDQKAYFKWKGDYVRNNISIEGIEGMLDM 700
              EM W ES A+        TV  L +RF   D++A FK K D  +  +  +   G+L+ 
Sbjct: 323  YLEMSWGESFAYLAGLE---TVSQLNNRFLKFDERA-FKTKVDLTKEPLPSKAFYGLLER 378

Query: 699  LMKEPHGQLQLMPYGGMMARTRSDATPYPHREGNLYSIGYLVTWNEDDNKRSDIYMDWVH 520
            L KEP+G + L  +GG M++  SD TP+PHR G    + Y+V WN+ + K+   ++DW+ 
Sbjct: 379  LSKEPNGFIALNGFGGQMSKISSDFTPFPHRSGTRLMVEYIVAWNQSEQKKKTEFLDWLE 438

Query: 519  GIHEYMTPFVSKGPRAAYVNELDLDLGVMDWGNHNISANELIELGRSWGEKYFLLNYERL 340
             ++E+M PFVSK PR  YVN +DLDLG +DWGN  +  N  IE+ RSWGE YFL NYERL
Sbjct: 439  KVYEFMKPFVSKNPRLGYVNHIDLDLGGIDWGNKTV-VNNAIEISRSWGESYFLSNYERL 497

Query: 339  VRAKTEIDPNNVFRHQQSIPP 277
            +RAKT IDPNNVF H QSIPP
Sbjct: 498  IRAKTLIDPNNVFNHPQSIPP 518


>gb|ACJ76784.1| berberine bridge enzyme 2 [Argemone mexicana]
          Length = 536

 Score =  476 bits (1226), Expect = e-131
 Identities = 243/501 (48%), Positives = 335/501 (66%), Gaps = 5/501 (0%)
 Frame = -3

Query: 1764 NFFSCISTEGV-NYTTPYAQ---EYHHSFGLAAYN-LRVTSAYARPIAIILPETKERLAA 1600
            +  SC+++ GV NYTTP +    +Y   F L+  N L   S  ++P  I+LP  KE L+ 
Sbjct: 33   DILSCLTSNGVHNYTTPSSDSNSDYLRLFHLSIQNPLFKKSTISKPSLIVLPGNKEELSN 92

Query: 1599 TIVCCRKTSWAFTFRSGGHSLEGLSYSAGNDHPFVMIDLMKLNQVVVDLESKTAWVEGGA 1420
            T+ CC + SW    RSGGHS EGLSY+A  D PFV+IDLM LN++ +D++S+TAWVE GA
Sbjct: 93   TVRCCTRGSWTIRLRSGGHSYEGLSYTA--DTPFVLIDLMNLNRISIDMDSETAWVESGA 150

Query: 1419 TLGEVYHAVGTLSNRLGFPAGYCPAVXXXXXXXXXXXGFMSRKYGLASDNVVDAILINAD 1240
            T+GE+Y+A+   ++  GF AG+CP V           G MSRKYGLA+DNV D ILI+++
Sbjct: 151  TVGELYYAISESTDSFGFTAGWCPTVGTGGHISGGGFGMMSRKYGLAADNVEDVILIDSN 210

Query: 1239 GQFLDRKSMGEDVFWAIRGGGAGSWGAVYSWKIRLVDVPETVTALRVTRHGSRSEAVKLL 1060
            G  LDRK MGEDVFWA+RGGG G WGA+Y+WKI+L+ VP+ VT  RV ++ +  EA  L+
Sbjct: 211  GAILDRKLMGEDVFWAVRGGGGGVWGAIYAWKIKLLPVPKKVTVFRVMKNVNIEEASFLI 270

Query: 1059 NKWQWVAPDLEDEFTLMASVIAESETSILTIFQGLYLGLKSSAVASITQVFPELEVVASE 880
            +KWQ+VA +L+D+FT+     A    + L +F GL+LG K+ A + + ++FPEL ++  E
Sbjct: 271  HKWQYVADELDDDFTVTILGGANGNGAWL-VFLGLHLGCKTVAKSIMDKMFPELGLIEEE 329

Query: 879  SKEMKWVESTAFFPDFTERFTVDDLKDRFATSDQKAYFKWKGDYVRNNISIEGIEGMLDM 700
              EM W ES A+        TV +L +RF   D KA FK K D+ +  + ++ I G+L++
Sbjct: 330  FLEMNWGESFAYLSGLK---TVKELNNRFLKLDDKA-FKTKVDFTKETLPLKVINGVLEI 385

Query: 699  LMKEPHGQLQLMPYGGMMARTRSDATPYPHREGNLYSIGYLVTWNEDDNKRSDIYMDWVH 520
            L KEP G + L   GG M++  +D TP+PHR G    + Y+V+W++D+  +SD + DW+ 
Sbjct: 386  LSKEPRGFILLNSLGGKMSKISNDFTPFPHRNGTKLMVEYIVSWSKDEESKSDEFFDWLR 445

Query: 519  GIHEYMTPFVSKGPRAAYVNELDLDLGVMDWGNHNISANELIELGRSWGEKYFLLNYERL 340
             I++YM  FVSK PR  YVN +DLDLG +DW N N S+N  IE+ R+WGEKYFL NYERL
Sbjct: 446  NIYDYMEEFVSKNPRVGYVNNIDLDLGGIDWSNKN-SSNNAIEIARNWGEKYFLSNYERL 504

Query: 339  VRAKTEIDPNNVFRHQQSIPP 277
            +RAKT IDPNN+F H QSIPP
Sbjct: 505  IRAKTLIDPNNIFNHPQSIPP 525


>pdb|3FWA|A Chain A, Structure Of Berberine Bridge Enzyme, C166a Variant In
            Complex With (S)-Reticuline
          Length = 497

 Score =  476 bits (1225), Expect = e-131
 Identities = 248/501 (49%), Positives = 331/501 (66%), Gaps = 5/501 (0%)
 Frame = -3

Query: 1764 NFFSCISTEGVNYTTPYAQEYHHSFG----LAAYN-LRVTSAYARPIAIILPETKERLAA 1600
            +  SC++  GV   T ++ +    F     L+  N L   S  ++P AIILP +KE L+ 
Sbjct: 1    DLLSCLTFNGVRNHTVFSADSDSDFNRFLHLSIQNPLFQNSLISKPSAIILPGSKEELSN 60

Query: 1599 TIVCCRKTSWAFTFRSGGHSLEGLSYSAGNDHPFVMIDLMKLNQVVVDLESKTAWVEGGA 1420
            TI C RK SW    RSGGHS EGLSY++  D PF++IDLM LN+V +DLES+TAWVE G+
Sbjct: 61   TIRCIRKGSWTIRLRSGGHSYEGLSYTS--DTPFILIDLMNLNRVSIDLESETAWVESGS 118

Query: 1419 TLGEVYHAVGTLSNRLGFPAGYCPAVXXXXXXXXXXXGFMSRKYGLASDNVVDAILINAD 1240
            TLGE+Y+A+   S++LGF AG+ P V           G MSRKYGLA+DNVVDAILI+A+
Sbjct: 119  TLGELYYAITESSSKLGFTAGWAPTVGTGGHISGGGFGMMSRKYGLAADNVVDAILIDAN 178

Query: 1239 GQFLDRKSMGEDVFWAIRGGGAGSWGAVYSWKIRLVDVPETVTALRVTRHGSRSEAVKLL 1060
            G  LDR++MGEDVFWAIRGGG G WGA+Y+WKI+L+ VPE VT  RVT++ +  EA  LL
Sbjct: 179  GAILDRQAMGEDVFWAIRGGGGGVWGAIYAWKIKLLPVPEKVTVFRVTKNVAIDEATSLL 238

Query: 1059 NKWQWVAPDLEDEFTLMASVIAESETSILTIFQGLYLGLKSSAVASITQVFPELEVVASE 880
            +KWQ+VA +LE++FTL     A+ +   LT+  G + GLK+ A ++   +FPEL +V  +
Sbjct: 239  HKWQFVAEELEEDFTLSVLGGADEKQVWLTML-GFHFGLKTVAKSTFDLLFPELGLVEED 297

Query: 879  SKEMKWVESTAFFPDFTERFTVDDLKDRFATSDQKAYFKWKGDYVRNNISIEGIEGMLDM 700
              EM W ES A+        TV  L +RF   D++A FK K D  +  +  +   G+L+ 
Sbjct: 298  YLEMSWGESFAYLAGLE---TVSQLNNRFLKFDERA-FKTKVDLTKEPLPSKAFYGLLER 353

Query: 699  LMKEPHGQLQLMPYGGMMARTRSDATPYPHREGNLYSIGYLVTWNEDDNKRSDIYMDWVH 520
            L KEP+G + L  +GG M++  SD TP+PHR G    + Y+V WN+ + K+   ++DW+ 
Sbjct: 354  LSKEPNGFIALNGFGGQMSKISSDFTPFPHRSGTRLMVEYIVAWNQSEQKKKTEFLDWLE 413

Query: 519  GIHEYMTPFVSKGPRAAYVNELDLDLGVMDWGNHNISANELIELGRSWGEKYFLLNYERL 340
             ++E+M PFVSK PR  YVN +DLDLG +DWGN  +  N  IE+ RSWGE YFL NYERL
Sbjct: 414  KVYEFMKPFVSKNPRLGYVNHIDLDLGGIDWGNKTV-VNNAIEISRSWGESYFLSNYERL 472

Query: 339  VRAKTEIDPNNVFRHQQSIPP 277
            +RAKT IDPNNVF H QSIPP
Sbjct: 473  IRAKTLIDPNNVFNHPQSIPP 493


>pdb|3FW8|A Chain A, Structure Of Berberine Bridge Enzyme, C166a Variant
          Length = 495

 Score =  476 bits (1225), Expect = e-131
 Identities = 248/501 (49%), Positives = 331/501 (66%), Gaps = 5/501 (0%)
 Frame = -3

Query: 1764 NFFSCISTEGVNYTTPYAQEYHHSFG----LAAYN-LRVTSAYARPIAIILPETKERLAA 1600
            +  SC++  GV   T ++ +    F     L+  N L   S  ++P AIILP +KE L+ 
Sbjct: 1    DLLSCLTFNGVRNHTVFSADSDSDFNRFLHLSIQNPLFQNSLISKPSAIILPGSKEELSN 60

Query: 1599 TIVCCRKTSWAFTFRSGGHSLEGLSYSAGNDHPFVMIDLMKLNQVVVDLESKTAWVEGGA 1420
            TI C RK SW    RSGGHS EGLSY++  D PF++IDLM LN+V +DLES+TAWVE G+
Sbjct: 61   TIRCIRKGSWTIRLRSGGHSYEGLSYTS--DTPFILIDLMNLNRVSIDLESETAWVESGS 118

Query: 1419 TLGEVYHAVGTLSNRLGFPAGYCPAVXXXXXXXXXXXGFMSRKYGLASDNVVDAILINAD 1240
            TLGE+Y+A+   S++LGF AG+ P V           G MSRKYGLA+DNVVDAILI+A+
Sbjct: 119  TLGELYYAITESSSKLGFTAGWAPTVGTGGHISGGGFGMMSRKYGLAADNVVDAILIDAN 178

Query: 1239 GQFLDRKSMGEDVFWAIRGGGAGSWGAVYSWKIRLVDVPETVTALRVTRHGSRSEAVKLL 1060
            G  LDR++MGEDVFWAIRGGG G WGA+Y+WKI+L+ VPE VT  RVT++ +  EA  LL
Sbjct: 179  GAILDRQAMGEDVFWAIRGGGGGVWGAIYAWKIKLLPVPEKVTVFRVTKNVAIDEATSLL 238

Query: 1059 NKWQWVAPDLEDEFTLMASVIAESETSILTIFQGLYLGLKSSAVASITQVFPELEVVASE 880
            +KWQ+VA +LE++FTL     A+ +   LT+  G + GLK+ A ++   +FPEL +V  +
Sbjct: 239  HKWQFVAEELEEDFTLSVLGGADEKQVWLTML-GFHFGLKTVAKSTFDLLFPELGLVEED 297

Query: 879  SKEMKWVESTAFFPDFTERFTVDDLKDRFATSDQKAYFKWKGDYVRNNISIEGIEGMLDM 700
              EM W ES A+        TV  L +RF   D++A FK K D  +  +  +   G+L+ 
Sbjct: 298  YLEMSWGESFAYLAGLE---TVSQLNNRFLKFDERA-FKTKVDLTKEPLPSKAFYGLLER 353

Query: 699  LMKEPHGQLQLMPYGGMMARTRSDATPYPHREGNLYSIGYLVTWNEDDNKRSDIYMDWVH 520
            L KEP+G + L  +GG M++  SD TP+PHR G    + Y+V WN+ + K+   ++DW+ 
Sbjct: 354  LSKEPNGFIALNGFGGQMSKISSDFTPFPHRSGTRLMVEYIVAWNQSEQKKKTEFLDWLE 413

Query: 519  GIHEYMTPFVSKGPRAAYVNELDLDLGVMDWGNHNISANELIELGRSWGEKYFLLNYERL 340
             ++E+M PFVSK PR  YVN +DLDLG +DWGN  +  N  IE+ RSWGE YFL NYERL
Sbjct: 414  KVYEFMKPFVSKNPRLGYVNHIDLDLGGIDWGNKTV-VNNAIEISRSWGESYFLSNYERL 472

Query: 339  VRAKTEIDPNNVFRHQQSIPP 277
            +RAKT IDPNNVF H QSIPP
Sbjct: 473  IRAKTLIDPNNVFNHPQSIPP 493


>ref|XP_006478292.1| PREDICTED: reticuline oxidase-like [Citrus sinensis]
          Length = 551

 Score =  476 bits (1224), Expect = e-131
 Identities = 240/512 (46%), Positives = 325/512 (63%), Gaps = 16/512 (3%)
 Frame = -3

Query: 1764 NFFSCISTEGVNYTTPYAQ-----------EYHHSFGLAAYNLRVT-SAYARPIAIILPE 1621
            NF  C++   VN  T +              Y+     +  NLR T S+  +P+AIILPE
Sbjct: 30   NFIYCLNRYNVNNFTLFPNIQNDHSEEANYNYYELLNFSIQNLRFTDSSVPKPVAIILPE 89

Query: 1620 TKERLAATIVCCRKTSWAFTFRSGGHSLEGLSYSAGNDHPFVMIDLMKLNQVVVDLESKT 1441
            + ++LA +++CCR  S     R GGHS EG S  + +   FV++D+  LN++ VDLES+T
Sbjct: 90   SIDQLANSVLCCRNESMELRVRCGGHSYEGTSSFSSDGASFVILDMSNLNKISVDLESET 149

Query: 1440 AWVEGGATLGEVYHAVGTLSNRLGFPAGYCPAVXXXXXXXXXXXGFMSRKYGLASDNVVD 1261
            AWV+GGATLGE Y A+   SN  GF AG CP V           G +SRKYGLA+DNVVD
Sbjct: 150  AWVQGGATLGETYSAISEASNTHGFSAGSCPTVGVGGHIGGGGFGLLSRKYGLAADNVVD 209

Query: 1260 AILINADGQFLDRKSMGEDVFWAIRGGGAGSWGAVYSWKIRLVDVPETVTALRVTRHGSR 1081
            A+L++A+G+ L+R++MGEDVFWAIRGGG G WG VY+WKI+L+ VP  V+   ++R GS+
Sbjct: 210  ALLMDANGRLLNREAMGEDVFWAIRGGGGGVWGIVYAWKIKLLQVPRVVSGFVLSRPGSK 269

Query: 1080 SEAVKLLNKWQWVAPDLEDEFTLM----ASVIAESETSILTIFQGLYLGLKSSAVASITQ 913
                KL+NKWQ VAP+L D+F L     A +       +   F+G YLG K  A+  +  
Sbjct: 270  QHVAKLVNKWQHVAPNLTDDFYLSCFIGAGLPETKSIGLSATFKGFYLGPKHEALTILNN 329

Query: 912  VFPELEVVASESKEMKWVESTAFFPDFTERFTVDDLKDRFATSDQKAYFKWKGDYVRNNI 733
             FPEL V   + KEM W+ES  FF   +   T+ DLK R+  +  K YFK K DYVR  I
Sbjct: 330  FFPELRVSEKDGKEMSWIESILFFSGLSNGSTISDLKKRY--NQDKNYFKAKSDYVRTPI 387

Query: 732  SIEGIEGMLDMLMKEPHGQLQLMPYGGMMARTRSDATPYPHREGNLYSIGYLVTWNEDDN 553
            S+ GI   L++L KEP G +   PYGG+M +  S+   +PHR GNL++I Y+V W E+DN
Sbjct: 388  SVTGIRTALEILDKEPKGYVIFDPYGGIMHKIGSEEIAFPHRNGNLFTIQYIVAWYEEDN 447

Query: 552  KRSDIYMDWVHGIHEYMTPFVSKGPRAAYVNELDLDLGVMDWGNHNISANELIELGRSWG 373
             +S+ Y+DW+   +  MTPFVS GPRAAY+N +D+DLG M+  N +  + + +E+ R WG
Sbjct: 448  DKSNGYIDWIRAFYNAMTPFVSWGPRAAYINYMDIDLGEMELINSSFPSKDAVEIARVWG 507

Query: 372  EKYFLLNYERLVRAKTEIDPNNVFRHQQSIPP 277
            EKYFL NY+RLV+AKT IDPNN+F +QQ IPP
Sbjct: 508  EKYFLKNYDRLVKAKTIIDPNNIFSNQQGIPP 539