BLASTX 2.2.25 [Feb-01-2011]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= Scutellaria24_contig00009958
         (2138 letters)

Database: ./nr 
           23,641,837 sequences; 8,123,359,852 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

dbj|BAE06274.1| topoisomerase II [Scutellaria baicalensis]           1047   0.0  
ref|XP_002274267.1| PREDICTED: DNA topoisomerase 2-like [Vitis v...   576   e-162
gb|AAN85207.1| DNA topoisomerase II [Nicotiana tabacum] gi|26984...   549   e-153
ref|XP_004165384.1| PREDICTED: LOW QUALITY PROTEIN: DNA topoisom...   516   e-144
ref|XP_004149716.1| PREDICTED: DNA topoisomerase 2-like [Cucumis...   515   e-143

>dbj|BAE06274.1| topoisomerase II [Scutellaria baicalensis]
          Length = 1469

 Score = 1047 bits (2707), Expect = 0.0
 Identities = 554/647 (85%), Positives = 554/647 (85%)
 Frame = -3

Query: 2136 RFLFPKADDILLDYLNEDGQSIEPTWYVPIIPMVLVNGSEGIGTGWSSYVPNYNPVDIIA 1957
            RFLFPKADDILLDYLNEDGQSIEPTWYVPIIPMVLVNGSEGIGTGWSSYVPNYNPVDIIA
Sbjct: 807  RFLFPKADDILLDYLNEDGQSIEPTWYVPIIPMVLVNGSEGIGTGWSSYVPNYNPVDIIA 866

Query: 1956 NIRHLLNDEATEPMHPWYKGFLGSVEKTATKEAGASYTVSGIIEEVDDTTLCIKELPIRR 1777
            NIRHLLNDEATEPMHPWYKGFLGSVEKTATKEAGASYTVSGIIEEVDDTTLCIKELPIRR
Sbjct: 867  NIRHLLNDEATEPMHPWYKGFLGSVEKTATKEAGASYTVSGIIEEVDDTTLCIKELPIRR 926

Query: 1776 WTQDYKEFLESVSAENDKSKDPFIEGCRDYSGSELVNFLVGMKPEKLEAAKREGLLKKFK 1597
            WTQDYKEFLESVSAENDKSKDPFIEGCRDYSGSELVNFLVGMKPEKLEAAKREGLLKKFK
Sbjct: 927  WTQDYKEFLESVSAENDKSKDPFIEGCRDYSGSELVNFLVGMKPEKLEAAKREGLLKKFK 986

Query: 1596 LTTSISTCNMHLFDSKGVIKKYDTPEQILEEFFYIRLELYEKRKKVLLDILEHDMLKCDN 1417
            LTTSISTCNMHLFDSKGVIKKYDTPEQILEEFFYIRLELYEKRKKVLLDILEHDMLKCDN
Sbjct: 987  LTTSISTCNMHLFDSKGVIKKYDTPEQILEEFFYIRLELYEKRKKVLLDILEHDMLKCDN 1046

Query: 1416 KYRFIRCVVEGSIIVSNRKRTDVFRELKEKGFTPFPKKKNRAEVAIAGATDDGEETEENS 1237
            KYRFIRCVVEGSIIVSNRKRTDVFRELKEKGFTPFPKKKNRAEVAIAGATDDGEETEENS
Sbjct: 1047 KYRFIRCVVEGSIIVSNRKRTDVFRELKEKGFTPFPKKKNRAEVAIAGATDDGEETEENS 1106

Query: 1236 EVPIAPGVXXXXXXXXXXLAIGTLTTEKMQELRAERDKLMQEVEELKQSTARSLWNKDLD 1057
            EVPIAPGV          LAIGTLTTEKMQELRAERDKLMQEVEELKQSTARSLWNKDLD
Sbjct: 1107 EVPIAPGVSSSDYDYLLSLAIGTLTTEKMQELRAERDKLMQEVEELKQSTARSLWNKDLD 1166

Query: 1056 ALEDKLAEEQKIYEETWEKNKRKIHGKTDTLEIIQXXXXXXXXXXXKESAVEMEISENTT 877
            ALEDKLAEEQKIYEETWEKNKRKIHGKTDTLEIIQ           KESAVEMEISENTT
Sbjct: 1167 ALEDKLAEEQKIYEETWEKNKRKIHGKTDTLEIIQKNPRKNKKTTKKESAVEMEISENTT 1226

Query: 876  TETDVKIXXXXXXXXXXXXXXXXXXXXXXXXXEQEDDDGIADLRQRIAAYNFDSSPDHSE 697
            TETDVKI                         EQEDDDGIADLRQRIAAYNFDSSPDHSE
Sbjct: 1227 TETDVKIKKPRGKAAAKKKEPAAKVVTAAPVEEQEDDDGIADLRQRIAAYNFDSSPDHSE 1286

Query: 696  DMATEVAPVQTKNKQPARRGAAQKKTLSAVSETDEDDDAFEPEEXXXXXXXXXXXXXXXX 517
            DMATEVAPVQTKNKQPARRGAAQKKTLSA SETDEDDDAFEPEE                
Sbjct: 1287 DMATEVAPVQTKNKQPARRGAAQKKTLSAASETDEDDDAFEPEEKKKKGGRKPAAAKAPA 1346

Query: 516  XXXXXXXXXKQSSQLVGQKLITEVLKPAADDSPEKKVRRMRESPFNKKSSSILGKTINIX 337
                     KQSSQLVGQKLITEVLKPAADDSPEKKVRRMRESPFNKKSSSILGKTINI 
Sbjct: 1347 AAKKRGPSAKQSSQLVGQKLITEVLKPAADDSPEKKVRRMRESPFNKKSSSILGKTINID 1406

Query: 336  XXXXXETSGTSSMNEGXXXXXXXXXXXXXXXKYVISDSESDPTEILV 196
                 ETSGTSSMNEG               KYVISDSESDPTEILV
Sbjct: 1407 DDDEEETSGTSSMNEG-AAAARPKRANRGKAKYVISDSESDPTEILV 1452


>ref|XP_002274267.1| PREDICTED: DNA topoisomerase 2-like [Vitis vinifera]
          Length = 1489

 Score =  576 bits (1485), Expect = e-162
 Identities = 341/683 (49%), Positives = 421/683 (61%), Gaps = 39/683 (5%)
 Frame = -3

Query: 2136 RFLFPKADDILLDYLNEDGQSIEPTWYVPIIPMVLVNGSEGIGTGWSSYVPNYNPVDIIA 1957
            RFLFPK DDILLDYLNEDGQSIEPTWYVP IPMVLVNGSEGIGTGWSS +PNYNP DIIA
Sbjct: 798  RFLFPKDDDILLDYLNEDGQSIEPTWYVPTIPMVLVNGSEGIGTGWSSSIPNYNPRDIIA 857

Query: 1956 NIRHLLNDEATEPMHPWYKGFLGSVEKT-ATKEAGASYTVSGIIEEVDDTTLCIKELPIR 1780
            N+R LLN E  EPM PWY+GF G++EKT  TK+    YTV GIIEEV++TTL I ELP+R
Sbjct: 858  NVRRLLNGEMMEPMDPWYRGFRGTIEKTDPTKQESVGYTVKGIIEEVNETTLRISELPVR 917

Query: 1779 RWTQDYKEFLESVSAENDKSKDPFIEGCRDYSGSELVNFLVGMKPEKLEAAKREGLLKKF 1600
            +WTQDYKEFLES+   NDK KDPFI+  ++++    V+F V M  E L  AK+EGLL+KF
Sbjct: 918  KWTQDYKEFLESIMTGNDKIKDPFIKDYKEHNDDTTVHFEVIMSEENLLMAKQEGLLQKF 977

Query: 1599 KLTTSISTCNMHLFDSKGVIKKYDTPEQILEEFFYIRLELYEKRKKVLLDILEHDMLKCD 1420
            KLTT IST NMHLFDS G IKKY+TPEQILEEFF++RLE YEKRK+VLLD LE ++LK +
Sbjct: 978  KLTTKISTSNMHLFDSNGTIKKYETPEQILEEFFHLRLEFYEKRKRVLLDNLELELLKLE 1037

Query: 1419 NKYRFIRCVVEGSIIVSNRKRTDVFRELKEKGFTPFPKKKNRAEVAIAGATDDGEETEEN 1240
            NK RFI  VV G IIVSNRKR D+F EL +KGFTPFPKK    E+A+AGATDD EE EEN
Sbjct: 1038 NKVRFILGVVRGEIIVSNRKRADLFHELHQKGFTPFPKKSKSVEIAVAGATDDTEEAEEN 1097

Query: 1239 SEVPIAPGVXXXXXXXXXXLAIGTLTTEKMQELRAERDKLMQEVEELKQSTARSLWNKDL 1060
            ++     GV          +AIGTLT EK+QEL A+RDKL + V++LK++T ++LW  DL
Sbjct: 1098 TDAVSKGGVRATDYEYLLSMAIGTLTLEKVQELCADRDKLNKGVDDLKKATPKALWITDL 1157

Query: 1059 DALEDKLAEEQK---IYEETWEKNKRKI---HGKTDTLEIIQXXXXXXXXXXXKESAVE- 901
            DALE +L E+ K     EET ++ K ++    G   + +  +            E A E 
Sbjct: 1158 DALERELDEQDKNDARAEETRKQLKSRVMSEAGMKVSRQAPKNPRKNNKKANNAEPAAET 1217

Query: 900  MEISENTTTETD-VKIXXXXXXXXXXXXXXXXXXXXXXXXXEQEDDDGIADLRQRIAAYN 724
            M++S ++  E + V                           + EDDD + +L++R+AAYN
Sbjct: 1218 MDVSASSAMEMESVPEVVKPKGRAAPRKAPAKKKEMPTSVLKDEDDDEVHELKERLAAYN 1277

Query: 723  FDSSPDHSEDMATEVAPV-QTKNKQPARRGAAQKKTLSA---VSETDEDDDAFEPEE--- 565
             +SSPD S  M  EV  V   + K+P+RR AAQKK L++   +S+ DEDD+ FE EE   
Sbjct: 1278 LESSPDGSAAMEAEVPQVPAARKKEPSRRAAAQKKPLASFTEISDDDEDDEDFEVEEVSA 1337

Query: 564  ----------XXXXXXXXXXXXXXXXXXXXXXXXXKQSSQLVGQKLITEVLKPA--ADDS 421
                                               KQ  QL+GQ L+TE+ KPA     S
Sbjct: 1338 SDVKKKGGRKPAANAKAAAAKPAAAAAKNKRGAANKQQPQLLGQTLLTEIFKPAETLGIS 1397

Query: 420  PEKKVRRMRESPFNKKSSSILGKT----------INIXXXXXXETSGTSSMNEGXXXXXX 271
            PEKKVR+MR SPFNKKS S+LG T           N        +SG  S          
Sbjct: 1398 PEKKVRKMRASPFNKKSGSVLGSTGEEDETAETEENSGSASTSNSSGGESNEVVMPARTR 1457

Query: 270  XXXXXXXXXKYVISDSESD-PTE 205
                     +YV+SDSESD PT+
Sbjct: 1458 PQRENRVQTRYVVSDSESDQPTD 1480


>gb|AAN85207.1| DNA topoisomerase II [Nicotiana tabacum] gi|26984168|gb|AAN85208.1|
            DNA topoisomerase II [Nicotiana tabacum]
          Length = 1482

 Score =  549 bits (1415), Expect = e-153
 Identities = 310/619 (50%), Positives = 389/619 (62%), Gaps = 24/619 (3%)
 Frame = -3

Query: 2136 RFLFPKADDILLDYLNEDGQSIEPTWYVPIIPMVLVNGSEGIGTGWSSYVPNYNPVDIIA 1957
            RFLFPK DD + DYLNEDGQ IEPTWYVPI+PMVL+NGSEGIGTGWSSYVPNYNP D++A
Sbjct: 794  RFLFPKEDDTIHDYLNEDGQYIEPTWYVPIVPMVLINGSEGIGTGWSSYVPNYNPRDLVA 853

Query: 1956 NIRHLLNDEATEPMHPWYKGFLGSVEKTATKEAGASYTVSGIIEEVDDTTLCIKELPIRR 1777
            N+R LLNDE  EPM PWYKGF G++EKTATKEAGA+YTV+GIIEEV++TTL I ELP+RR
Sbjct: 854  NVRRLLNDEPMEPMDPWYKGFKGTIEKTATKEAGATYTVTGIIEEVNETTLRISELPVRR 913

Query: 1776 WTQDYKEFLESVSAENDKSKDPFIEGCRDYSGSELVNFLVGMKPEKLEAAKREGLLKKFK 1597
            WT+DYK+FLES++  NDK+KDPFI+  R Y     V F V M  E L  A++EGLLKKFK
Sbjct: 914  WTEDYKQFLESMTVSNDKAKDPFIKEVRAYGDENSVCFEVIMSEENLILAQQEGLLKKFK 973

Query: 1596 LTTSISTCNMHLFDSKGVIKKYDTPEQILEEFFYIRLELYEKRKKVLLDILEHDMLKCDN 1417
            L T+IST NMHLFDS G IKKYD PE ILEEF+++RLE YEKRKK LL+ILE ++L+ +N
Sbjct: 974  LATTISTSNMHLFDSNGKIKKYDNPEDILEEFYHVRLEYYEKRKKALLEILELELLRIEN 1033

Query: 1416 KYRFIRCVVEGSIIVSNRKRTDVFRELKEKGFTPFPKKKNRAEVAIAGATDDGEETEENS 1237
            K +FI  VV+  IIV+NRKR D+  ELKEKGFTPFPKKK   E  +A  +DD E++EE  
Sbjct: 1034 KVKFILGVVKVEIIVNNRKRADLLLELKEKGFTPFPKKK-AVEAVVADTSDDAEDSEEE- 1091

Query: 1236 EVPIAPGVXXXXXXXXXXLAIGTLTTEKMQELRAERDKLMQEVEELKQSTARSLWNKDLD 1057
               +  GV          + IGTLT EK+QEL AERD+L  EVE+++ +T + LW KDLD
Sbjct: 1092 ---LNRGVRAGDYDYLLSMPIGTLTLEKVQELCAERDQLNGEVEDMRNATPKLLWLKDLD 1148

Query: 1056 ALEDKLAEEQKI---YEETWEKNKRKIHGKTDTLEIIQXXXXXXXXXXXKESAVE---ME 895
             LE +L E+ KI    EE  EK K+K+                       ES  E     
Sbjct: 1149 VLEKQLDEQDKIDIQAEEAREKIKKKVMNAAGLKAPKPKPRKNVKKASVVESTAEPMDRV 1208

Query: 894  ISENTTTETDVKIXXXXXXXXXXXXXXXXXXXXXXXXXEQEDDDGIADLRQRIAAYNFDS 715
               N+   ++V                           E+E+DD +  L+ R+AAYN +S
Sbjct: 1209 SCFNSGNRSNVTEVVKPKARGGSKKAPAKAKPIAVEDEEEEEDDEVLALKDRLAAYNLNS 1268

Query: 714  SPDHSEDMATEVAPVQTKNKQPARRGAAQKKTLSAVSETDE--------DDDAFEPE--- 568
            SPDHS +     AP + + K P R+ AA+KKTL ++++  E        DDD  EPE   
Sbjct: 1269 SPDHSAEAMETEAP-KAQKKAPTRKAAAKKKTLPSIADVSEGEDEIEISDDDESEPEVAV 1327

Query: 567  ----EXXXXXXXXXXXXXXXXXXXXXXXXXKQSSQLVGQKLITEVLKPAA---DDSPEKK 409
                +                          + +  +GQKLIT +LKPA    + SPEKK
Sbjct: 1328 GGKKKGGRKPATAKAAPAAAKQPPKKRGPANKQAVGIGQKLITSILKPAENTDNSSPEKK 1387

Query: 408  VRRMRESPFNKKSSSILGK 352
            VR+MR SPFN+KS ++LGK
Sbjct: 1388 VRKMRASPFNEKSGAVLGK 1406


>ref|XP_004165384.1| PREDICTED: LOW QUALITY PROTEIN: DNA topoisomerase 2-like [Cucumis
            sativus]
          Length = 1460

 Score =  516 bits (1329), Expect = e-144
 Identities = 302/631 (47%), Positives = 390/631 (61%), Gaps = 34/631 (5%)
 Frame = -3

Query: 2136 RFLFPKADDILLDYLNEDGQSIEPTWYVPIIPMVLVNGSEGIGTGWSSYVPNYNPVDIIA 1957
            RFLFP+ DD LL+YLNEDGQSIEPTWY+PIIP VLVNGSEGIGTGWSSYVPNYNP DII 
Sbjct: 762  RFLFPRDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIR 821

Query: 1956 NIRHLLNDEATEPMHPWYKGFLGSVEKTATKEAGASYTVSGIIEEVDDTTLCIKELPIRR 1777
            N+R +L  E   PM PWY+GF G++EKTATKE G +YTVSGIIEEV DTTL I ELP+RR
Sbjct: 822  NVRRMLEGETMLPMDPWYRGFSGTIEKTATKEGGTTYTVSGIIEEVSDTTLRIVELPVRR 881

Query: 1776 WTQDYKEFLES---VSAENDK-----SKDPFIEGCRDYSGSELVNFLVGMKPEKLEAAKR 1621
            WT DYK+FL+S   V++++DK     +KDPFIE    +S  ++V+  V +  E +  A +
Sbjct: 882  WTSDYKDFLDSVTRVASKHDKDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENMLLAIQ 941

Query: 1620 EGLLKKFKLTTSISTCNMHLFDSKGVIKKYDTPEQILEEFFYIRLELYEKRKKVLLDILE 1441
            EGL KKFKLTT++ST NMHLFD+ GVIKKYDTPEQILEEFF +RLE YEKRK++LLD LE
Sbjct: 942  EGLKKKFKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRILLDNLE 1001

Query: 1440 HDMLKCDNKYRFIRCVVEGSIIVSNRKRTDVFRELKEKGFTPFPKKKNRAEVAIAGATDD 1261
             ++LK +NK RFI  VV   I VSNRK+ D+F EL+ KGFTPFPKK    E  IAGA+++
Sbjct: 1002 MELLKLENKVRFILAVVNEEIKVSNRKKVDLFHELQAKGFTPFPKKTKSVEPEIAGASNE 1061

Query: 1260 GEETEENSEVPIAPGVXXXXXXXXXXLAIGTLTTEKMQELRAERDKLMQEVEELKQSTAR 1081
             +E EE+ EV    G           L IGTLT EK+QEL ++RDKL  EV++L+++T +
Sbjct: 1062 TDEAEESPEV--VKGERISDYEYLLALPIGTLTIEKVQELCSDRDKLKGEVDDLRKATPK 1119

Query: 1080 SLWNKDLDALEDKLAEEQKIYEETWE-----KNKRKIHGKTDTLEIIQXXXXXXXXXXXK 916
            SLW  DLD LE +L E  +   +T E     + K  I  K                    
Sbjct: 1120 SLWLNDLDYLEKELDEMDRNDAQTMELRKQQREKANIDLKPKVSRNAPKAPRNSKKTSNV 1179

Query: 915  ESAVEMEISENTTTETDVK----IXXXXXXXXXXXXXXXXXXXXXXXXXEQEDDDGIADL 748
            E+  E   +  ++T T+V     +                         E ++DD + +L
Sbjct: 1180 ETVTESMDTTYSSTTTEVANNPVVKPKGKAAPRKAPAKKKGKAAVLDDDEDDEDDEVLEL 1239

Query: 747  RQRIAAYNFDSSPDHSE--DMATEVAPVQ---TKNKQPARRGAAQKKTLS-----AVSET 598
            + R+AAY  +SSP+ SE   M TEV  VQ    K K+P++R  A+KKT +     ++S+ 
Sbjct: 1240 KDRLAAYKIESSPEPSEVSAMETEVQEVQQQAAKKKEPSKRAPAKKKTTAKSAQISISDD 1299

Query: 597  DEDDD----AFEPEEXXXXXXXXXXXXXXXXXXXXXXXXXKQSSQLVGQKLITEVLKPAA 430
            D D D      +P                             +   +GQKLIT++L+PAA
Sbjct: 1300 DNDGDFEIKEVDPPAAKKGGGRGGGGGRKAAAGNSKTTKPPAAGAKLGQKLITQMLEPAA 1359

Query: 429  DD---SPEKKVRRMRESPFNKKSSSILGKTI 346
            ++   SPEKKVR++R SPFNKKS S+LG+TI
Sbjct: 1360 ENSGISPEKKVRKIRASPFNKKSGSLLGRTI 1390


>ref|XP_004149716.1| PREDICTED: DNA topoisomerase 2-like [Cucumis sativus]
          Length = 1459

 Score =  515 bits (1327), Expect = e-143
 Identities = 304/630 (48%), Positives = 393/630 (62%), Gaps = 33/630 (5%)
 Frame = -3

Query: 2136 RFLFPKADDILLDYLNEDGQSIEPTWYVPIIPMVLVNGSEGIGTGWSSYVPNYNPVDIIA 1957
            RFLFP+ DD LL+YLNEDGQSIEPTWY+PIIP VLVNGSEGIGTGWSSYVPNYNP DII 
Sbjct: 762  RFLFPRDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIR 821

Query: 1956 NIRHLLNDEATEPMHPWYKGFLGSVEKTATKEAGASYTVSGIIEEVDDTTLCIKELPIRR 1777
            N+R +L  E   PM PWY+GF G++EKTATKE G +YTVSGIIEEV DTTL I ELP+RR
Sbjct: 822  NVRRMLEGETMLPMDPWYRGFSGTIEKTATKEGGTTYTVSGIIEEVSDTTLRIVELPVRR 881

Query: 1776 WTQDYKEFLES---VSAENDK-----SKDPFIEGCRDYSGSELVNFLVGMKPEKLEAAKR 1621
            WT DYK+FL+S   V++++DK     +KDPFIE    +S  ++V+  V +  E +  A +
Sbjct: 882  WTSDYKDFLDSVTRVASKHDKDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENMLLAIQ 941

Query: 1620 EGLLKKFKLTTSISTCNMHLFDSKGVIKKYDTPEQILEEFFYIRLELYEKRKKVLLDILE 1441
            EGL KKFKLTT++ST NMHLFD+ GVIKKYDTPEQILEEFF +RLE YEKRK++LLD LE
Sbjct: 942  EGLKKKFKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRILLDNLE 1001

Query: 1440 HDMLKCDNKYRFIRCVVEGSIIVSNRKRTDVFRELKEKGFTPFPKKKNRAEVAIAGATDD 1261
             ++LK +NK RFI  VV   I VSNRK+ D+F EL+ KGFTPFPKK    E  IAGA+++
Sbjct: 1002 MELLKLENKVRFILAVVNEEIKVSNRKKVDLFHELQAKGFTPFPKKTKSVEPEIAGASNE 1061

Query: 1260 GEETEENSEVPIAPGVXXXXXXXXXXLAIGTLTTEKMQELRAERDKLMQEVEELKQSTAR 1081
             +E EE+ EV    G           L IGTLT EK+QEL ++RDKL  EV++L+++T +
Sbjct: 1062 TDEAEESPEV--VKGERISDYEYLLALPIGTLTIEKVQELCSDRDKLKGEVDDLRKATPK 1119

Query: 1080 SLWNKDLDALEDKLAEEQKIYEETWE-----KNKRKIHGKTDTLEIIQXXXXXXXXXXXK 916
            SLW  DLD LE +L E  +   +T E     + K  I  K                    
Sbjct: 1120 SLWLNDLDYLEKELDEMDRNDAQTMELRKQQREKANIDLKPKVSRNAPKAPRNSKKTSNV 1179

Query: 915  ESAVEMEISENTTTETDVK----IXXXXXXXXXXXXXXXXXXXXXXXXXEQEDDDGIADL 748
            E+  E   +  ++T T+V     +                         E ++DD + +L
Sbjct: 1180 ETVTESMDTTYSSTTTEVANNPVVKPKGKAAPRKAPAKKKGKAAVLDDDEDDEDDEVLEL 1239

Query: 747  RQRIAAYNFDSSPDHSE--DMATEVAPVQ---TKNKQPARRGAAQKKTL---SAVSETDE 592
            + R+AAY  +SSP+ SE   M TEV  VQ    K K+P++R  A+KKT    + +S +D+
Sbjct: 1240 KDRLAAYKIESSPEPSEVSAMETEVQEVQQQAAKKKEPSKRAPAKKKTTAKSAQISISDD 1299

Query: 591  DDDA-FEPEE----XXXXXXXXXXXXXXXXXXXXXXXXXKQSSQLVGQKLITEVLKPAAD 427
            D+D  FE +E                               +   +GQKLIT++L+PAA+
Sbjct: 1300 DNDGDFEIKEVDPPAAKKGGGRGGGGRKAAAGNSKTTKPPAAGAKLGQKLITQMLEPAAE 1359

Query: 426  D---SPEKKVRRMRESPFNKKSSSILGKTI 346
            +   SPEKKVR++R SPFNKKS S+LG+TI
Sbjct: 1360 NSGISPEKKVRKIRASPFNKKSGSLLGRTI 1389