BLASTX 2.2.25 [Feb-01-2011]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= Scutellaria22_contig00007076
         (2253 letters)

Database: ./nr 
           23,641,837 sequences; 8,123,359,852 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

ref|XP_002519105.1| Protein ariadne-1, putative [Ricinus communi...   868   0.0  
ref|XP_002284665.1| PREDICTED: probable E3 ubiquitin-protein lig...   863   0.0  
ref|XP_004145339.1| PREDICTED: probable E3 ubiquitin-protein lig...   849   0.0  
ref|XP_002313070.1| predicted protein [Populus trichocarpa] gi|2...   836   0.0  
ref|XP_003631625.1| PREDICTED: probable E3 ubiquitin-protein lig...   822   0.0  

>ref|XP_002519105.1| Protein ariadne-1, putative [Ricinus communis]
            gi|223541768|gb|EEF43316.1| Protein ariadne-1, putative
            [Ricinus communis]
          Length = 592

 Score =  868 bits (2244), Expect = 0.0
 Identities = 407/571 (71%), Positives = 476/571 (83%), Gaps = 4/571 (0%)
 Frame = -1

Query: 1992 LDGLESKESDAHWGASKAPSCKVITKESLLAAQKEDLRRVMDLLSVGEHHARTLLIHYQW 1813
            LDG+E++ESD HW   K P+ K+ITKESLLAAQ+EDLRRVM+LLS+ EHHARTLLIHY+W
Sbjct: 21   LDGIENEESDFHWAPPKGPTTKIITKESLLAAQREDLRRVMELLSLREHHARTLLIHYRW 80

Query: 1812 DIEKLIALYVEKGKSCIFSEAGVTVAELVDLD-PDEPTSTVMCNICMDDAPANDVTLMDC 1636
            D+E+L A++VEKGK+ +F+EAGVT  E +D D P   +S +MC+IC++D P N  T MDC
Sbjct: 81   DVERLFAVFVEKGKTFLFTEAGVTGVEQLDRDAPLTSSSIIMCDICIEDVPGNRATRMDC 140

Query: 1635 GHCFCNSCWTEHFIVKINEGQSKRIRCMAHKCNAICDEAIVRKLVSKRYPDLVEKFDRFL 1456
             HCFCN CWTEHFIVKINEGQS+RI+CMAHKCNAICDEA+VR LVSKR+PDL E+FDRFL
Sbjct: 141  SHCFCNDCWTEHFIVKINEGQSRRIQCMAHKCNAICDEAVVRNLVSKRHPDLAERFDRFL 200

Query: 1455 LESYIEDNKMVKWCPSIPHCGNAIRVDHDEFCEVECSCGMQFCFSCVSEAHSPCSCVMWK 1276
            LESYIEDNKMVKWCPS PHCGNAIRV+ DE CEVECSCG+QFCFSC+SEAHSPCSC+MW+
Sbjct: 201  LESYIEDNKMVKWCPSAPHCGNAIRVEEDECCEVECSCGLQFCFSCLSEAHSPCSCLMWE 260

Query: 1275 LWTKKCHDESETVNWITVHTKPCPKCHKPVEKNGGCNLVSCICGQAFCWLCGGATGRDHT 1096
            LW+KKC DESETVNWITVHTKPCPKCHKPVEKNGGCNLVSCICGQAFCWLCGGATG+DHT
Sbjct: 261  LWSKKCRDESETVNWITVHTKPCPKCHKPVEKNGGCNLVSCICGQAFCWLCGGATGKDHT 320

Query: 1095 WSSITNHSCGRYXXXXXXXXXXXXXDLYRYMHYHNRYKAHTDSFKLESRLRETLKEKVAH 916
            WS I+ HSCGRY             DLYRYMHYHNRYKAHTDSFKLE++L+ET+ EKV+ 
Sbjct: 321  WSRISGHSCGRYKEDREKKTERAKRDLYRYMHYHNRYKAHTDSFKLETKLKETILEKVSI 380

Query: 915  LEARDSKLRDFSWATNGLYRLFRSRRALSYSYPFAFYMFGDDLFKDEMTEKEKEINQHLF 736
             E ++S+LRDFSW TNGL RLFRSRR LSYSYPFAFYMFGD+LF DEMT +E+EI Q+LF
Sbjct: 381  SEEKESRLRDFSWVTNGLCRLFRSRRVLSYSYPFAFYMFGDELFNDEMTVEEREIKQNLF 440

Query: 735  EDQQQQLESNVEKLSKFLEEPFDEYPEDQIMQIRMHVINLCVVIDKLCKKMYECIENELL 556
            EDQQQQLESNVEKLSKFLEEPF++Y +D++M+IRM VINLC + D LCKKMYECIEN+LL
Sbjct: 441  EDQQQQLESNVEKLSKFLEEPFEQYTDDKVMEIRMQVINLCAITDTLCKKMYECIENDLL 500

Query: 555  GSLQFTIHNIAPYQSKGIEKAEELTFGWSAQASSNGKRKEAN-QSNGGVVEADKASASGT 379
            GSLQ   HNIAPY+SKGIEKA EL+  WS + ++  K   ++  ++GG  E D+ S S +
Sbjct: 501  GSLQLGTHNIAPYKSKGIEKASELSSCWSNKVNATDKCLPSDGNTSGGSSEHDRPSGSRS 560

Query: 378  LGESLQYLRKRPRK--GGFADSSFDLNMPAD 292
              +S    RKR RK  GGF    FDLN+PA+
Sbjct: 561  SDDSGCSSRKRARKEGGGF----FDLNLPAE 587


>ref|XP_002284665.1| PREDICTED: probable E3 ubiquitin-protein ligase ARI1 isoform 1 [Vitis
            vinifera] gi|297741410|emb|CBI32541.3| unnamed protein
            product [Vitis vinifera]
          Length = 589

 Score =  863 bits (2229), Expect = 0.0
 Identities = 407/567 (71%), Positives = 468/567 (82%), Gaps = 1/567 (0%)
 Frame = -1

Query: 1989 DGLESKESDAHWGASKAPSCKVITKESLLAAQKEDLRRVMDLLSVGEHHARTLLIHYQWD 1810
            DGL ++ESD  W   KAPS +VITKESLL AQ++DLRRVMDLLS+ EHHARTLLIH++WD
Sbjct: 20   DGLVNEESDFQWVPPKAPSSQVITKESLLTAQRDDLRRVMDLLSLREHHARTLLIHHRWD 79

Query: 1809 IEKLIALYVEKGKSCIFSEAGVTVAELVDLDPDEPTSTVMCNICMDDAPANDVTLMDCGH 1630
            +EKL A+ VEKGK C+F+EAGV + E   +     +ST+MC+ICM+   + D T MDCGH
Sbjct: 80   VEKLFAVMVEKGKPCLFAEAGVPLMEHQIVPLPLSSSTLMCDICMEAVCSKDSTKMDCGH 139

Query: 1629 CFCNSCWTEHFIVKINEGQSKRIRCMAHKCNAICDEAIVRKLVSKRYPDLVEKFDRFLLE 1450
            CFCN+CWTEHF+V+INEGQS+RIRCMA+KCNAICDEAIVR LV +R+PDL EKFDRFLLE
Sbjct: 140  CFCNNCWTEHFVVRINEGQSRRIRCMAYKCNAICDEAIVRNLVGRRHPDLAEKFDRFLLE 199

Query: 1449 SYIEDNKMVKWCPSIPHCGNAIRVDHDEFCEVECSCGMQFCFSCVSEAHSPCSCVMWKLW 1270
            SYIEDNKMVKWCPS PHCGNAIRV+ DEFCEVECSCG+QFCFSC+SEAHSPCSC+MW+ W
Sbjct: 200  SYIEDNKMVKWCPSAPHCGNAIRVEDDEFCEVECSCGLQFCFSCLSEAHSPCSCLMWEFW 259

Query: 1269 TKKCHDESETVNWITVHTKPCPKCHKPVEKNGGCNLVSCICGQAFCWLCGGATGRDHTWS 1090
            TKKC DESETVNWITVHTKPCPKCHKPVEKNGGCNLVSCICGQAFCWLCGGATGRDHTWS
Sbjct: 260  TKKCRDESETVNWITVHTKPCPKCHKPVEKNGGCNLVSCICGQAFCWLCGGATGRDHTWS 319

Query: 1089 SITNHSCGRYXXXXXXXXXXXXXDLYRYMHYHNRYKAHTDSFKLESRLRETLKEKVAHLE 910
            SI+ HSCGRY             DLYRYMHYHNRYKAHTDSFKLES+L++T+K KV++ E
Sbjct: 320  SISGHSCGRYKEDREKKAERAKRDLYRYMHYHNRYKAHTDSFKLESKLKDTIKVKVSNSE 379

Query: 909  ARDSKLRDFSWATNGLYRLFRSRRALSYSYPFAFYMFGDDLFKDEMTEKEKEINQHLFED 730
             ++S LRDFSW TNGLYRLFRSRR LSYSYPFAFYMFGDDLF DEMT++E+EI QHLFED
Sbjct: 380  EKESTLRDFSWVTNGLYRLFRSRRVLSYSYPFAFYMFGDDLFNDEMTKEEREIKQHLFED 439

Query: 729  QQQQLESNVEKLSKFLEEPFDEYPEDQIMQIRMHVINLCVVIDKLCKKMYECIENELLGS 550
            QQQQLE+NVEKLSKF+EEPFD+Y ED++  IRM VINL V+ D LCKKMYECIEN+LLGS
Sbjct: 440  QQQQLEANVEKLSKFIEEPFDQYEEDKVRDIRMQVINLSVITDTLCKKMYECIENDLLGS 499

Query: 549  LQFTIHNIAPYQSKGIEKAEELTFGWSAQAS-SNGKRKEANQSNGGVVEADKASASGTLG 373
            LQ  IHNIAPY+SKGIE+A EL    S +AS ++      N ++GG  E D+ S SG+  
Sbjct: 500  LQHGIHNIAPYKSKGIERASELITCQSNKASNADNCPSSENGTDGGTAEFDRPSGSGSSY 559

Query: 372  ESLQYLRKRPRKGGFADSSFDLNMPAD 292
            ES    RKR RK G      DLN+PA+
Sbjct: 560  ESGYSSRKRARKEGL--GGIDLNLPAE 584


>ref|XP_004145339.1| PREDICTED: probable E3 ubiquitin-protein ligase ARI1-like [Cucumis
            sativus] gi|449471519|ref|XP_004153333.1| PREDICTED:
            probable E3 ubiquitin-protein ligase ARI1-like [Cucumis
            sativus] gi|449502370|ref|XP_004161621.1| PREDICTED:
            probable E3 ubiquitin-protein ligase ARI1-like [Cucumis
            sativus]
          Length = 589

 Score =  849 bits (2193), Expect = 0.0
 Identities = 401/568 (70%), Positives = 473/568 (83%), Gaps = 1/568 (0%)
 Frame = -1

Query: 1992 LDGLESKESDAHWGASKAPSCKVITKESLLAAQKEDLRRVMDLLSVGEHHARTLLIHYQW 1813
            L GLE+++S+      K PS KVITKESLLAAQKED+RRVMDLLS+ E+HARTLLIHY+W
Sbjct: 19   LHGLENEDSEIQ-RVPKTPSTKVITKESLLAAQKEDMRRVMDLLSLREYHARTLLIHYRW 77

Query: 1812 DIEKLIALYVEKGKSCIFSEAGVTVAELVDLDPDEPTSTVMCNICMDDAPANDVTLMDCG 1633
            D+EKL A+ VEKGK+ +F+ AGVT+ E       E +S VMC+ICM++   ND T +DCG
Sbjct: 78   DVEKLFAVLVEKGKNHLFATAGVTMIENRSNTSSEASSMVMCDICMEEVHGNDATRVDCG 137

Query: 1632 HCFCNSCWTEHFIVKINEGQSKRIRCMAHKCNAICDEAIVRKLVSKRYPDLVEKFDRFLL 1453
            HCFCN+CWTEHFIVKINEGQS+RIRCMAHKCNAICDEA+VR LVSKR+PDL  KFDRFLL
Sbjct: 138  HCFCNNCWTEHFIVKINEGQSRRIRCMAHKCNAICDEAVVRTLVSKRHPDLANKFDRFLL 197

Query: 1452 ESYIEDNKMVKWCPSIPHCGNAIRVDHDEFCEVECSCGMQFCFSCVSEAHSPCSCVMWKL 1273
            ESYIEDNK VKWCPS PHCGNAIRV+ DEFCEVECSCG+QFCFSC+SEAHSPCSC+MW+L
Sbjct: 198  ESYIEDNKRVKWCPSTPHCGNAIRVEDDEFCEVECSCGLQFCFSCLSEAHSPCSCLMWEL 257

Query: 1272 WTKKCHDESETVNWITVHTKPCPKCHKPVEKNGGCNLVSCICGQAFCWLCGGATGRDHTW 1093
            W KKC DESETVNWITVHTKPCPKCHKPVEKNGGCNLVSCICGQAFCWLCGGATGR+HTW
Sbjct: 258  WIKKCRDESETVNWITVHTKPCPKCHKPVEKNGGCNLVSCICGQAFCWLCGGATGREHTW 317

Query: 1092 SSITNHSCGRYXXXXXXXXXXXXXDLYRYMHYHNRYKAHTDSFKLESRLRETLKEKVAHL 913
            SSI+ HSCGRY             DLYRYMHYHNRYKAHTDSFKLES+L+E+++EK++  
Sbjct: 318  SSISGHSCGRYKEESEQKAERAKRDLYRYMHYHNRYKAHTDSFKLESKLKESIQEKISIS 377

Query: 912  EARDSKLRDFSWATNGLYRLFRSRRALSYSYPFAFYMFGDDLFKDEMTEKEKEINQHLFE 733
            E R+S LRDFSW  NGL RLFRSRR LSYSYPFAFYMFGD+LFKDEMTE E+EI QHLFE
Sbjct: 378  EERESMLRDFSWVNNGLSRLFRSRRVLSYSYPFAFYMFGDELFKDEMTEAEREIKQHLFE 437

Query: 732  DQQQQLESNVEKLSKFLEEPFDEYPEDQIMQIRMHVINLCVVIDKLCKKMYECIENELLG 553
            DQQQQLE+NVEKLSKFLEEPFD+Y +D++M+IRM VINL V+ D LCKKMY+CIEN+LLG
Sbjct: 438  DQQQQLEANVEKLSKFLEEPFDQYTKDKVMEIRMQVINLSVITDTLCKKMYDCIENDLLG 497

Query: 552  SLQFTIHNIAPYQSKGIEKAEELTFGWSAQASSNGKRKEAN-QSNGGVVEADKASASGTL 376
            SL+  IHNIAPY+SKGIEKA EL+  W+++A+++ K   ++  ++GG+ E ++ ++  + 
Sbjct: 498  SLELGIHNIAPYKSKGIEKALELSACWNSKANTSDKYPPSDCGTSGGLSECERLTSLNS- 556

Query: 375  GESLQYLRKRPRKGGFADSSFDLNMPAD 292
             E+    RKR R    A + FDLN+PA+
Sbjct: 557  EENGCSSRKRARAEVVAGNFFDLNLPAE 584


>ref|XP_002313070.1| predicted protein [Populus trichocarpa] gi|222849478|gb|EEE87025.1|
            predicted protein [Populus trichocarpa]
          Length = 591

 Score =  836 bits (2159), Expect = 0.0
 Identities = 397/596 (66%), Positives = 475/596 (79%), Gaps = 4/596 (0%)
 Frame = -1

Query: 2067 EEDYYMSGNXXXXXXXXXXXXXXXSLDGLESKESDA-HWGASKAPSCKVITKESLLAAQK 1891
            EEDYY + +                 DGL   +  A  W   K  + KVITKESLLAAQ+
Sbjct: 12   EEDYYYADDGDSH-------------DGLADNDDSALQWAPPKGSTTKVITKESLLAAQR 58

Query: 1890 EDLRRVMDLLSVGEHHARTLLIHYQWDIEKLIALYVEKGKSCIFSEAGVTVAELVDLD-P 1714
            EDLRRVMDLLS+ EHHARTLLIHY+WD+EKL+A+ VEKGKSC+F+EAGVTV E VD + P
Sbjct: 59   EDLRRVMDLLSLKEHHARTLLIHYRWDVEKLLAVLVEKGKSCLFTEAGVTVVENVDDEVP 118

Query: 1713 DEPTSTVMCNICMDDAPANDVTLMDCGHCFCNSCWTEHFIVKINEGQSKRIRCMAHKCNA 1534
               +ST+ C+IC++DA A++ T M+CGHCFCN+CWTEHFI+KINEGQS+RI+CMAH+C+A
Sbjct: 119  PSSSSTITCDICIEDATADNATRMECGHCFCNNCWTEHFIIKINEGQSRRIQCMAHRCSA 178

Query: 1533 ICDEAIVRKLVSKRYPDLVEKFDRFLLESYIEDNKMVKWCPSIPHCGNAIRVDHDEFCEV 1354
            ICDEAIVR LVS+R+P+L EKFDRFLLESYIEDNKMVKWCPSIPHCG AIRV+ DEFCEV
Sbjct: 179  ICDEAIVRNLVSRRHPNLAEKFDRFLLESYIEDNKMVKWCPSIPHCGKAIRVEEDEFCEV 238

Query: 1353 ECSCGMQFCFSCVSEAHSPCSCVMWKLWTKKCHDESETVNWITVHTKPCPKCHKPVEKNG 1174
            ECSCG+QFCFSC+SEAHSPCSC+MW+ W+KKCHDESETVNWITVHTKPCPKC+KPVEKNG
Sbjct: 239  ECSCGLQFCFSCLSEAHSPCSCLMWERWSKKCHDESETVNWITVHTKPCPKCYKPVEKNG 298

Query: 1173 GCNLVSCICGQAFCWLCGGATGRDHTWSSITNHSCGRYXXXXXXXXXXXXXDLYRYMHYH 994
            GCNLVSCICGQ+FCW+CGGATGRDHTWS I  HSCGRY             DLYRYMHYH
Sbjct: 299  GCNLVSCICGQSFCWVCGGATGRDHTWSRIAGHSCGRYKEDREKQTERAKRDLYRYMHYH 358

Query: 993  NRYKAHTDSFKLESRLRETLKEKVAHLEARDSKLRDFSWATNGLYRLFRSRRALSYSYPF 814
            NR+KAHTDSFKLES+L+E++ +KV+  E R+ +L+DFSW TNGL RLFRSRR LSYSYPF
Sbjct: 359  NRFKAHTDSFKLESKLKESILDKVSVAEERELRLKDFSWVTNGLNRLFRSRRVLSYSYPF 418

Query: 813  AFYMFGDDLFKDEMTEKEKEINQHLFEDQQQQLESNVEKLSKFLEEPFDEYPEDQIMQIR 634
            AFYMFG++ FKDEMT++E+EI ++LFEDQQQQLESNVEKLS FLEEPF ++ +D++M IR
Sbjct: 419  AFYMFGEEFFKDEMTDEEREIKKNLFEDQQQQLESNVEKLSMFLEEPFQQFSQDKVMDIR 478

Query: 633  MHVINLCVVIDKLCKKMYECIENELLGSLQFTIHNIAPYQSKGIEKAEELTFGWSAQASS 454
            M VINL V ID LC+KMYECIE++LLGSL    H+IAPY+SKGIE+A EL+  W+ +  S
Sbjct: 479  MRVINLSVTIDTLCQKMYECIESDLLGSLHLGTHHIAPYKSKGIERASELSSCWNTKLGS 538

Query: 453  NGKRKEANQSNGGVVEADKASASGTLGESLQYLRKRPRK--GGFADSSFDLNMPAD 292
                 +    +GG  E D+ S SG+  +S    RKR +K  GGF    FDLN+PA+
Sbjct: 539  T----DEYLPSGGTSEHDRPSGSGSSDDSGCSYRKRAKKEGGGF----FDLNLPAE 586


>ref|XP_003631625.1| PREDICTED: probable E3 ubiquitin-protein ligase ARI1 isoform 2 [Vitis
            vinifera]
          Length = 573

 Score =  822 bits (2123), Expect = 0.0
 Identities = 396/567 (69%), Positives = 456/567 (80%), Gaps = 1/567 (0%)
 Frame = -1

Query: 1989 DGLESKESDAHWGASKAPSCKVITKESLLAAQKEDLRRVMDLLSVGEHHARTLLIHYQWD 1810
            DGL ++ESD  W   KAPS +VITKESLL AQ++DLRRVMDLLS+ EHHARTLLIH++WD
Sbjct: 20   DGLVNEESDFQWVPPKAPSSQVITKESLLTAQRDDLRRVMDLLSLREHHARTLLIHHRWD 79

Query: 1809 IEKLIALYVEKGKSCIFSEAGVTVAELVDLDPDEPTSTVMCNICMDDAPANDVTLMDCGH 1630
            +EKL A+ VEKGK C+F+EAGV + E   +     +ST+MC+ICM+              
Sbjct: 80   VEKLFAVMVEKGKPCLFAEAGVPLMEHQIVPLPLSSSTLMCDICME-------------- 125

Query: 1629 CFCNSCWTEHFIVKINEGQSKRIRCMAHKCNAICDEAIVRKLVSKRYPDLVEKFDRFLLE 1450
              C+  WTEHF+V+INEGQS+RIRCMA+KCNAICDEAIVR LV +R+PDL EKFDRFLLE
Sbjct: 126  AVCS--WTEHFVVRINEGQSRRIRCMAYKCNAICDEAIVRNLVGRRHPDLAEKFDRFLLE 183

Query: 1449 SYIEDNKMVKWCPSIPHCGNAIRVDHDEFCEVECSCGMQFCFSCVSEAHSPCSCVMWKLW 1270
            SYIEDNKMVKWCPS PHCGNAIRV+ DEFCEVECSCG+QFCFSC+SEAHSPCSC+MW+ W
Sbjct: 184  SYIEDNKMVKWCPSAPHCGNAIRVEDDEFCEVECSCGLQFCFSCLSEAHSPCSCLMWEFW 243

Query: 1269 TKKCHDESETVNWITVHTKPCPKCHKPVEKNGGCNLVSCICGQAFCWLCGGATGRDHTWS 1090
            TKKC DESETVNWITVHTKPCPKCHKPVEKNGGCNLVSCICGQAFCWLCGGATGRDHTWS
Sbjct: 244  TKKCRDESETVNWITVHTKPCPKCHKPVEKNGGCNLVSCICGQAFCWLCGGATGRDHTWS 303

Query: 1089 SITNHSCGRYXXXXXXXXXXXXXDLYRYMHYHNRYKAHTDSFKLESRLRETLKEKVAHLE 910
            SI+ HSCGRY             DLYRYMHYHNRYKAHTDSFKLES+L++T+K KV++ E
Sbjct: 304  SISGHSCGRYKEDREKKAERAKRDLYRYMHYHNRYKAHTDSFKLESKLKDTIKVKVSNSE 363

Query: 909  ARDSKLRDFSWATNGLYRLFRSRRALSYSYPFAFYMFGDDLFKDEMTEKEKEINQHLFED 730
             ++S LRDFSW TNGLYRLFRSRR LSYSYPFAFYMFGDDLF DEMT++E+EI QHLFED
Sbjct: 364  EKESTLRDFSWVTNGLYRLFRSRRVLSYSYPFAFYMFGDDLFNDEMTKEEREIKQHLFED 423

Query: 729  QQQQLESNVEKLSKFLEEPFDEYPEDQIMQIRMHVINLCVVIDKLCKKMYECIENELLGS 550
            QQQQLE+NVEKLSKF+EEPFD+Y ED++  IRM VINL V+ D LCKKMYECIEN+LLGS
Sbjct: 424  QQQQLEANVEKLSKFIEEPFDQYEEDKVRDIRMQVINLSVITDTLCKKMYECIENDLLGS 483

Query: 549  LQFTIHNIAPYQSKGIEKAEELTFGWSAQAS-SNGKRKEANQSNGGVVEADKASASGTLG 373
            LQ  IHNIAPY+SKGIE+A EL    S +AS ++      N ++GG  E D+ S SG+  
Sbjct: 484  LQHGIHNIAPYKSKGIERASELITCQSNKASNADNCPSSENGTDGGTAEFDRPSGSGSSY 543

Query: 372  ESLQYLRKRPRKGGFADSSFDLNMPAD 292
            ES    RKR RK G      DLN+PA+
Sbjct: 544  ESGYSSRKRARKEGL--GGIDLNLPAE 568