BLASTX 2.2.26 [Sep-21-2011]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= Rehmannia30_contig00006137
         (4686 letters)

Database: All non-redundant GenBank CDS
translations+PDB+SwissProt+PIR+PRF excluding environmental samples
from WGS projects 
           149,584,005 sequences; 54,822,741,787 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

ref|XP_011087923.1| DNA topoisomerase 2 isoform X2 [Sesamum indi...  2382   0.0  
ref|XP_011087914.1| DNA topoisomerase 2 isoform X1 [Sesamum indi...  2382   0.0  
ref|XP_012849677.1| PREDICTED: DNA topoisomerase 2 [Erythranthe ...  2329   0.0  
dbj|BAE06274.1| topoisomerase II [Scutellaria baicalensis]           2225   0.0  
gb|KZV36276.1| DNA topoisomerase 2 [Dorcoceras hygrometricum]        2162   0.0  
gb|EPS67102.1| hypothetical protein M569_07672 [Genlisea aurea]      2029   0.0  
gb|EPS73185.1| hypothetical protein M569_01571, partial [Genlise...  2009   0.0  
gb|PIN08559.1| DNA topoisomerase type II [Handroanthus impetigin...  1947   0.0  
ref|XP_010241214.1| PREDICTED: DNA topoisomerase 2-like isoform ...  1937   0.0  
ref|XP_010241213.1| PREDICTED: DNA topoisomerase 2-like isoform ...  1932   0.0  
emb|CDP07797.1| unnamed protein product [Coffea canephora]           1932   0.0  
ref|XP_022896608.1| DNA topoisomerase 2 [Olea europaea var. sylv...  1928   0.0  
ref|XP_002274267.1| PREDICTED: DNA topoisomerase 2 [Vitis vinifera]  1922   0.0  
gb|OVA19386.1| DNA topoisomerase II [Macleaya cordata]               1903   0.0  
ref|XP_015881654.1| PREDICTED: DNA topoisomerase 2 isoform X2 [Z...  1885   0.0  
ref|XP_015881653.1| PREDICTED: DNA topoisomerase 2 isoform X1 [Z...  1881   0.0  
gb|EOY18137.1| DNA topoisomerase 2 isoform 1 [Theobroma cacao]       1878   0.0  
ref|XP_007009327.2| PREDICTED: DNA topoisomerase 2 [Theobroma ca...  1875   0.0  
gb|OWM78385.1| hypothetical protein CDL15_Pgr016109 [Punica gran...  1872   0.0  
ref|XP_021295966.1| DNA topoisomerase 2 [Herrania umbratica]         1871   0.0  

>ref|XP_011087923.1| DNA topoisomerase 2 isoform X2 [Sesamum indicum]
          Length = 1483

 Score = 2382 bits (6174), Expect = 0.0
 Identities = 1214/1470 (82%), Positives = 1283/1470 (87%), Gaps = 6/1470 (0%)
 Frame = +1

Query: 67   MAGAKKAPLTTSNNANIPPSETVTAAGG--KKTIEQTYQKKTQLEHILLRPDTYIGSIEK 240
            MAGAKKAPLTTSNNANIPP ET  A GG  KKTIEQTYQKKTQLEHILLRPDTYIGSIEK
Sbjct: 1    MAGAKKAPLTTSNNANIPPPETTIAGGGAGKKTIEQTYQKKTQLEHILLRPDTYIGSIEK 60

Query: 241  HTQTLWVYENEQMVQKSITFVPGLYKIFDEILVNAADNKQRDPKMDSVKVTIDVESSCIS 420
            HTQTLWVYE+EQMVQKSIT+VPGLYKIFDEILVNAADNKQRDPKMDSVKVTIDVES+ IS
Sbjct: 61   HTQTLWVYEDEQMVQKSITYVPGLYKIFDEILVNAADNKQRDPKMDSVKVTIDVESNSIS 120

Query: 421  VYNNGDGVPVEIHQEEGVYVPELIFGHLLTSSNYDDNEKKTTGGRNGYGAKLTNIFSTEF 600
            VYNNGDGVPVEIHQEEGVYVPELIFGHLLTSSNYDDNEKKTTGGRNGYGAKLTNIFSTEF
Sbjct: 121  VYNNGDGVPVEIHQEEGVYVPELIFGHLLTSSNYDDNEKKTTGGRNGYGAKLTNIFSTEF 180

Query: 601  VIETADGKRQRKYKQVFSNNMGTKTEPIISKCKAGENWTRITFKPDLVKFSMSYLEEDVV 780
            VIETADGKRQRKYKQVFSNNMGTK+EPIISKCKAGENWT+ITFKPDL KFSMSYLEEDVV
Sbjct: 181  VIETADGKRQRKYKQVFSNNMGTKSEPIISKCKAGENWTKITFKPDLAKFSMSYLEEDVV 240

Query: 781  ALMKKRVIDVAGCLGKTVKVELNGQLFHFKSFSNYCDLYMKSTSVSTLDPLPRFEEEVHD 960
            ALMKKRVIDVAGCLGKTVKVELNG+LFHFKSFSNYCDLY+K  S S+ DPLPRFEEEVHD
Sbjct: 241  ALMKKRVIDVAGCLGKTVKVELNGRLFHFKSFSNYCDLYLKPASASSSDPLPRFEEEVHD 300

Query: 961  RWQVCISRSEGQFQQVSFVNGIATVKGGTHVDYVTNKITSHLVSVIXXXXXXXXXFDLKP 1140
            RWQ+CISRSEGQFQQVSFVNGIATVKGGTHVDYVTNKITSHLV+VI         FDLKP
Sbjct: 301  RWQICISRSEGQFQQVSFVNGIATVKGGTHVDYVTNKITSHLVTVIKNKNKKNKKFDLKP 360

Query: 1141 HTVKNHLWVFVNALIDNPAFDSQTKETLTLRAASFGSSWDFSSKFLDKVAKSDIMKNIEE 1320
            H VKNHLWVFVNALIDNPAFDSQTKETLTLRAASFGSSWDFSSKFLDKVAKSDIMKNIEE
Sbjct: 361  HAVKNHLWVFVNALIDNPAFDSQTKETLTLRAASFGSSWDFSSKFLDKVAKSDIMKNIEE 420

Query: 1321 WAEFKQKKDLKKTDGSKDRRIYGLAKLADANEAGGKNSEKCTLILTEGDSAKALAIAGLS 1500
            WAEFKQKKDLKKTDGSKDRRIYGL KLADANEAGGKNSEKCTLILTEGDSAKALAIAGLS
Sbjct: 421  WAEFKQKKDLKKTDGSKDRRIYGLTKLADANEAGGKNSEKCTLILTEGDSAKALAIAGLS 480

Query: 1501 VVGRDHYGVFPLRGKLLNVREASHNQLMQNVEIQHIKQILGLQHGKQYDSVKPLRYGHLM 1680
            VVGRDHYGVFPLRGKLLNVREASHNQLMQNVEIQHIKQILGLQHGKQYDSVK LRYGHLM
Sbjct: 481  VVGRDHYGVFPLRGKLLNVREASHNQLMQNVEIQHIKQILGLQHGKQYDSVKSLRYGHLM 540

Query: 1681 IMTDQDHDGSHIKGLLINFIHSFWPSLLKVPTFLLEFITPIVKATHRDGKRKESFYTMPQ 1860
            IMTDQDHDGSHIKGLLINFIHSFWPSLLKVPTFLLEFITPIVKA+ +DGK+KESFYTMPQ
Sbjct: 541  IMTDQDHDGSHIKGLLINFIHSFWPSLLKVPTFLLEFITPIVKASRKDGKKKESFYTMPQ 600

Query: 1861 YETWKQNQGTDVKNWTIKYYKGLGTSTDQEAKEYFEALGRHKKDFVWVDEQDGDAIELAF 2040
            YE WK+  G D KNW+IKYYKGLGTSTDQE KEYFE LG+HKKDFVWVDEQDG+AIELAF
Sbjct: 601  YEAWKEKLGADAKNWSIKYYKGLGTSTDQEGKEYFEDLGKHKKDFVWVDEQDGEAIELAF 660

Query: 2041 SKKKIEARKNWLRQFEPGTYLCDLEEHIKYRDFVHKELILFSIADLQRSIPSMVDGLKPG 2220
            SKKKIEARKNW+RQFEPGTYL + ++HIKYRDFVHKELILFSIADLQRSIPSMVDGLKPG
Sbjct: 661  SKKKIEARKNWIRQFEPGTYLSEQDKHIKYRDFVHKELILFSIADLQRSIPSMVDGLKPG 720

Query: 2221 QRKILFCSFKRNFIKEAKVAQFSGYVSEHSAYHHGEQSLASTIIGMAQDYVGSNNINLLL 2400
            QRKILFCSFKRNFIKEAKVAQFSGYVSEHSAYHHGEQSLASTIIGMAQDYVGSNNINLLL
Sbjct: 721  QRKILFCSFKRNFIKEAKVAQFSGYVSEHSAYHHGEQSLASTIIGMAQDYVGSNNINLLL 780

Query: 2401 PNGQFGTRGQGGKDHASARYIYTQLSSITRFLFPKADDFLLNYLNEDGQSIEPTWYVPTI 2580
            PNGQFGTRGQGGKDHASARYI+TQLS ITR+LFPKADD LLNYLNEDGQSIEP+WYVP I
Sbjct: 781  PNGQFGTRGQGGKDHASARYIFTQLSPITRYLFPKADDILLNYLNEDGQSIEPSWYVPII 840

Query: 2581 PMVLVNGSEGIGTGWSTFIPNYNPLDIIANVRHLLNDEPMEPMHPWYKGFIGSIEKTATK 2760
            PMVLVNGSEGIGTGWS+FIPNYNPLDIIAN+RHLLNDEPM PMHPWYKGF GSIEKTATK
Sbjct: 841  PMVLVNGSEGIGTGWSSFIPNYNPLDIIANLRHLLNDEPMVPMHPWYKGFRGSIEKTATK 900

Query: 2761 EAGNSYTVSGIIEEVDETSLRITELPIRKWTQDYKEFLESVSAENDKSKDPFIEGCRDNS 2940
            EAGNSYTVSGIIEE+DE +L ITELP+RKWTQDYKEFLES+SAEN+KSKDPFIEGCRDNS
Sbjct: 901  EAGNSYTVSGIIEELDERTLSITELPVRKWTQDYKEFLESISAENEKSKDPFIEGCRDNS 960

Query: 2941 GGEIVHFSVYMSPNNLSEAKQEGLMKKFKLTTSISTSNMHLFDSKGVIKKYDTPEQIIEE 3120
            GGEIV+F VY+S  NL  AKQEGL+KKFKLTTSISTSNMHLFD+KGVIKKYDTPEQI+EE
Sbjct: 961  GGEIVNFLVYLSAENLLIAKQEGLLKKFKLTTSISTSNMHLFDAKGVIKKYDTPEQILEE 1020

Query: 3121 FFHIRLEFYDKRKKALLANLENDMLKCDNKYRFIRGVVDGSIIVSNRKRADLFLELKEKG 3300
            FFHIRLEFY+KRK+ LLANLENDMLKC+NK RFI+ VV+ SIIVSNR+RADLFLELKEKG
Sbjct: 1021 FFHIRLEFYEKRKRVLLANLENDMLKCENKCRFIQCVVESSIIVSNRRRADLFLELKEKG 1080

Query: 3301 FTPFPKKKTAAEIAIAGSTDDADESEENNDVAIGKGVSASDYDYLLSLAIGTLTAEKMKE 3480
            FTPFPKKKTAAE+AIAGS D+A+E+EEN         SASDYDYLLSLAIGTLTAEK++E
Sbjct: 1081 FTPFPKKKTAAEVAIAGSLDEAEETEEN--------TSASDYDYLLSLAIGTLTAEKIQE 1132

Query: 3481 LRDERDKLMQEVEELKRATVKSLWMHDLDALESKFIEELNKSEKKWAENRQRILGEAKGT 3660
            LR ERDKLMQEVE LKRATVKSLWM+DLDALESKFIEE NKSEKKW + R++I G    +
Sbjct: 1133 LRAERDKLMQEVENLKRATVKSLWMNDLDALESKFIEEQNKSEKKWEKEREKINGTVNIS 1192

Query: 3661 RPVQTKPRKNTKKASNKESVVEQMEVSDNTVTETDKVGEVXXXXXXXXXXXXXXXXXXXX 3840
            RPVQ  PRKN KKA+NKES   QMEVS +TV E    G++                    
Sbjct: 1193 RPVQKNPRKNNKKATNKES---QMEVSGDTVPEAGNAGDI--KKPKGRTAAKKKAPAEKV 1247

Query: 3841 XXXXXXXXXXXXXXLRHRLAAYNFDSSPDRSEDMETEQ-PQMPTKKKEPNRRTAAQKKPL 4017
                          LRHRLAAYNFDSSPDR ++METE+  Q+ TKKKEP+R+ AAQKKPL
Sbjct: 1248 TSVADENDDEEISDLRHRLAAYNFDSSPDRPQEMETEEVSQLQTKKKEPSRKAAAQKKPL 1307

Query: 4018 STVSETXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXTKPPLAGTKKRGQQANKQQT 4197
             TVSE+                                   KPP   TKKRG  A+KQ  
Sbjct: 1308 PTVSES-HDDDDIQIIDDDDDFVPDEKKKKGGRKPGNAKAAKPP--STKKRGPAASKQSQ 1364

Query: 4198 ---QKLITEVLKPAENSPEKKVRKMRASPFNKKSSSILGRTISVDXXXXXXXXXXXXNSV 4368
               QKLITEVLKPAENSPEKKVRK+RASPFNKKS SILGRTI+V+            +S 
Sbjct: 1365 TLGQKLITEVLKPAENSPEKKVRKVRASPFNKKSGSILGRTINVEEEEEGSTSAEQADST 1424

Query: 4369 STLGSVTEDVSQAVAPKARPQRGTRGNARY 4458
            STLGSVT DV QAVAPKARPQR  RG A Y
Sbjct: 1425 STLGSVT-DVGQAVAPKARPQRANRGKATY 1453


>ref|XP_011087914.1| DNA topoisomerase 2 isoform X1 [Sesamum indicum]
          Length = 1484

 Score = 2382 bits (6174), Expect = 0.0
 Identities = 1214/1470 (82%), Positives = 1283/1470 (87%), Gaps = 6/1470 (0%)
 Frame = +1

Query: 67   MAGAKKAPLTTSNNANIPPSETVTAAGG--KKTIEQTYQKKTQLEHILLRPDTYIGSIEK 240
            MAGAKKAPLTTSNNANIPP ET  A GG  KKTIEQTYQKKTQLEHILLRPDTYIGSIEK
Sbjct: 1    MAGAKKAPLTTSNNANIPPPETTIAGGGAGKKTIEQTYQKKTQLEHILLRPDTYIGSIEK 60

Query: 241  HTQTLWVYENEQMVQKSITFVPGLYKIFDEILVNAADNKQRDPKMDSVKVTIDVESSCIS 420
            HTQTLWVYE+EQMVQKSIT+VPGLYKIFDEILVNAADNKQRDPKMDSVKVTIDVES+ IS
Sbjct: 61   HTQTLWVYEDEQMVQKSITYVPGLYKIFDEILVNAADNKQRDPKMDSVKVTIDVESNSIS 120

Query: 421  VYNNGDGVPVEIHQEEGVYVPELIFGHLLTSSNYDDNEKKTTGGRNGYGAKLTNIFSTEF 600
            VYNNGDGVPVEIHQEEGVYVPELIFGHLLTSSNYDDNEKKTTGGRNGYGAKLTNIFSTEF
Sbjct: 121  VYNNGDGVPVEIHQEEGVYVPELIFGHLLTSSNYDDNEKKTTGGRNGYGAKLTNIFSTEF 180

Query: 601  VIETADGKRQRKYKQVFSNNMGTKTEPIISKCKAGENWTRITFKPDLVKFSMSYLEEDVV 780
            VIETADGKRQRKYKQVFSNNMGTK+EPIISKCKAGENWT+ITFKPDL KFSMSYLEEDVV
Sbjct: 181  VIETADGKRQRKYKQVFSNNMGTKSEPIISKCKAGENWTKITFKPDLAKFSMSYLEEDVV 240

Query: 781  ALMKKRVIDVAGCLGKTVKVELNGQLFHFKSFSNYCDLYMKSTSVSTLDPLPRFEEEVHD 960
            ALMKKRVIDVAGCLGKTVKVELNG+LFHFKSFSNYCDLY+K  S S+ DPLPRFEEEVHD
Sbjct: 241  ALMKKRVIDVAGCLGKTVKVELNGRLFHFKSFSNYCDLYLKPASASSSDPLPRFEEEVHD 300

Query: 961  RWQVCISRSEGQFQQVSFVNGIATVKGGTHVDYVTNKITSHLVSVIXXXXXXXXXFDLKP 1140
            RWQ+CISRSEGQFQQVSFVNGIATVKGGTHVDYVTNKITSHLV+VI         FDLKP
Sbjct: 301  RWQICISRSEGQFQQVSFVNGIATVKGGTHVDYVTNKITSHLVTVIKNKNKKNKKFDLKP 360

Query: 1141 HTVKNHLWVFVNALIDNPAFDSQTKETLTLRAASFGSSWDFSSKFLDKVAKSDIMKNIEE 1320
            H VKNHLWVFVNALIDNPAFDSQTKETLTLRAASFGSSWDFSSKFLDKVAKSDIMKNIEE
Sbjct: 361  HAVKNHLWVFVNALIDNPAFDSQTKETLTLRAASFGSSWDFSSKFLDKVAKSDIMKNIEE 420

Query: 1321 WAEFKQKKDLKKTDGSKDRRIYGLAKLADANEAGGKNSEKCTLILTEGDSAKALAIAGLS 1500
            WAEFKQKKDLKKTDGSKDRRIYGL KLADANEAGGKNSEKCTLILTEGDSAKALAIAGLS
Sbjct: 421  WAEFKQKKDLKKTDGSKDRRIYGLTKLADANEAGGKNSEKCTLILTEGDSAKALAIAGLS 480

Query: 1501 VVGRDHYGVFPLRGKLLNVREASHNQLMQNVEIQHIKQILGLQHGKQYDSVKPLRYGHLM 1680
            VVGRDHYGVFPLRGKLLNVREASHNQLMQNVEIQHIKQILGLQHGKQYDSVK LRYGHLM
Sbjct: 481  VVGRDHYGVFPLRGKLLNVREASHNQLMQNVEIQHIKQILGLQHGKQYDSVKSLRYGHLM 540

Query: 1681 IMTDQDHDGSHIKGLLINFIHSFWPSLLKVPTFLLEFITPIVKATHRDGKRKESFYTMPQ 1860
            IMTDQDHDGSHIKGLLINFIHSFWPSLLKVPTFLLEFITPIVKA+ +DGK+KESFYTMPQ
Sbjct: 541  IMTDQDHDGSHIKGLLINFIHSFWPSLLKVPTFLLEFITPIVKASRKDGKKKESFYTMPQ 600

Query: 1861 YETWKQNQGTDVKNWTIKYYKGLGTSTDQEAKEYFEALGRHKKDFVWVDEQDGDAIELAF 2040
            YE WK+  G D KNW+IKYYKGLGTSTDQE KEYFE LG+HKKDFVWVDEQDG+AIELAF
Sbjct: 601  YEAWKEKLGADAKNWSIKYYKGLGTSTDQEGKEYFEDLGKHKKDFVWVDEQDGEAIELAF 660

Query: 2041 SKKKIEARKNWLRQFEPGTYLCDLEEHIKYRDFVHKELILFSIADLQRSIPSMVDGLKPG 2220
            SKKKIEARKNW+RQFEPGTYL + ++HIKYRDFVHKELILFSIADLQRSIPSMVDGLKPG
Sbjct: 661  SKKKIEARKNWIRQFEPGTYLSEQDKHIKYRDFVHKELILFSIADLQRSIPSMVDGLKPG 720

Query: 2221 QRKILFCSFKRNFIKEAKVAQFSGYVSEHSAYHHGEQSLASTIIGMAQDYVGSNNINLLL 2400
            QRKILFCSFKRNFIKEAKVAQFSGYVSEHSAYHHGEQSLASTIIGMAQDYVGSNNINLLL
Sbjct: 721  QRKILFCSFKRNFIKEAKVAQFSGYVSEHSAYHHGEQSLASTIIGMAQDYVGSNNINLLL 780

Query: 2401 PNGQFGTRGQGGKDHASARYIYTQLSSITRFLFPKADDFLLNYLNEDGQSIEPTWYVPTI 2580
            PNGQFGTRGQGGKDHASARYI+TQLS ITR+LFPKADD LLNYLNEDGQSIEP+WYVP I
Sbjct: 781  PNGQFGTRGQGGKDHASARYIFTQLSPITRYLFPKADDILLNYLNEDGQSIEPSWYVPII 840

Query: 2581 PMVLVNGSEGIGTGWSTFIPNYNPLDIIANVRHLLNDEPMEPMHPWYKGFIGSIEKTATK 2760
            PMVLVNGSEGIGTGWS+FIPNYNPLDIIAN+RHLLNDEPM PMHPWYKGF GSIEKTATK
Sbjct: 841  PMVLVNGSEGIGTGWSSFIPNYNPLDIIANLRHLLNDEPMVPMHPWYKGFRGSIEKTATK 900

Query: 2761 EAGNSYTVSGIIEEVDETSLRITELPIRKWTQDYKEFLESVSAENDKSKDPFIEGCRDNS 2940
            EAGNSYTVSGIIEE+DE +L ITELP+RKWTQDYKEFLES+SAEN+KSKDPFIEGCRDNS
Sbjct: 901  EAGNSYTVSGIIEELDERTLSITELPVRKWTQDYKEFLESISAENEKSKDPFIEGCRDNS 960

Query: 2941 GGEIVHFSVYMSPNNLSEAKQEGLMKKFKLTTSISTSNMHLFDSKGVIKKYDTPEQIIEE 3120
            GGEIV+F VY+S  NL  AKQEGL+KKFKLTTSISTSNMHLFD+KGVIKKYDTPEQI+EE
Sbjct: 961  GGEIVNFLVYLSAENLLIAKQEGLLKKFKLTTSISTSNMHLFDAKGVIKKYDTPEQILEE 1020

Query: 3121 FFHIRLEFYDKRKKALLANLENDMLKCDNKYRFIRGVVDGSIIVSNRKRADLFLELKEKG 3300
            FFHIRLEFY+KRK+ LLANLENDMLKC+NK RFI+ VV+ SIIVSNR+RADLFLELKEKG
Sbjct: 1021 FFHIRLEFYEKRKRVLLANLENDMLKCENKCRFIQCVVESSIIVSNRRRADLFLELKEKG 1080

Query: 3301 FTPFPKKKTAAEIAIAGSTDDADESEENNDVAIGKGVSASDYDYLLSLAIGTLTAEKMKE 3480
            FTPFPKKKTAAE+AIAGS D+A+E+EEN         SASDYDYLLSLAIGTLTAEK++E
Sbjct: 1081 FTPFPKKKTAAEVAIAGSLDEAEETEEN--------TSASDYDYLLSLAIGTLTAEKIQE 1132

Query: 3481 LRDERDKLMQEVEELKRATVKSLWMHDLDALESKFIEELNKSEKKWAENRQRILGEAKGT 3660
            LR ERDKLMQEVE LKRATVKSLWM+DLDALESKFIEE NKSEKKW + R++I G    +
Sbjct: 1133 LRAERDKLMQEVENLKRATVKSLWMNDLDALESKFIEEQNKSEKKWEKEREKINGTVNIS 1192

Query: 3661 RPVQTKPRKNTKKASNKESVVEQMEVSDNTVTETDKVGEVXXXXXXXXXXXXXXXXXXXX 3840
            RPVQ  PRKN KKA+NKES   QMEVS +TV E    G++                    
Sbjct: 1193 RPVQKNPRKNNKKATNKES---QMEVSGDTVPEAGNAGDI-KKPKGRTAAKKKAPAEKQV 1248

Query: 3841 XXXXXXXXXXXXXXLRHRLAAYNFDSSPDRSEDMETEQ-PQMPTKKKEPNRRTAAQKKPL 4017
                          LRHRLAAYNFDSSPDR ++METE+  Q+ TKKKEP+R+ AAQKKPL
Sbjct: 1249 TSVADENDDEEISDLRHRLAAYNFDSSPDRPQEMETEEVSQLQTKKKEPSRKAAAQKKPL 1308

Query: 4018 STVSETXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXTKPPLAGTKKRGQQANKQQT 4197
             TVSE+                                   KPP   TKKRG  A+KQ  
Sbjct: 1309 PTVSES-HDDDDIQIIDDDDDFVPDEKKKKGGRKPGNAKAAKPP--STKKRGPAASKQSQ 1365

Query: 4198 ---QKLITEVLKPAENSPEKKVRKMRASPFNKKSSSILGRTISVDXXXXXXXXXXXXNSV 4368
               QKLITEVLKPAENSPEKKVRK+RASPFNKKS SILGRTI+V+            +S 
Sbjct: 1366 TLGQKLITEVLKPAENSPEKKVRKVRASPFNKKSGSILGRTINVEEEEEGSTSAEQADST 1425

Query: 4369 STLGSVTEDVSQAVAPKARPQRGTRGNARY 4458
            STLGSVT DV QAVAPKARPQR  RG A Y
Sbjct: 1426 STLGSVT-DVGQAVAPKARPQRANRGKATY 1454


>ref|XP_012849677.1| PREDICTED: DNA topoisomerase 2 [Erythranthe guttata]
 gb|EYU27037.1| hypothetical protein MIMGU_mgv1a000169mg [Erythranthe guttata]
          Length = 1503

 Score = 2329 bits (6036), Expect = 0.0
 Identities = 1176/1477 (79%), Positives = 1276/1477 (86%), Gaps = 13/1477 (0%)
 Frame = +1

Query: 67   MAGAKKAPLTTSNNANIPPSETVTAA----GGKKTIEQTYQKKTQLEHILLRPDTYIGSI 234
            MAGAKK PLTTSNNANIPPSET  AA    GGKKTIEQTYQKKTQLEHILLRPDTYIGSI
Sbjct: 1    MAGAKKPPLTTSNNANIPPSETTAAAAAAGGGKKTIEQTYQKKTQLEHILLRPDTYIGSI 60

Query: 235  EKHTQTLWVYENEQMVQKSITFVPGLYKIFDEILVNAADNKQRDPKMDSVKVTIDVESSC 414
            EKHTQTLW+YENE MVQKSIT+VPGLYKIFDEILVNAADNKQRDP+MDSVKVTIDVES+ 
Sbjct: 61   EKHTQTLWIYENENMVQKSITYVPGLYKIFDEILVNAADNKQRDPRMDSVKVTIDVESNY 120

Query: 415  ISVYNNGDGVPVEIHQEEGVYVPELIFGHLLTSSNYDDNEKKTTGGRNGYGAKLTNIFST 594
            ISVYNNGDGVPVEIHQEEGVYVPELIFGHLLTSSNYDDNEKKTTGGRNGYGAKLTNIFST
Sbjct: 121  ISVYNNGDGVPVEIHQEEGVYVPELIFGHLLTSSNYDDNEKKTTGGRNGYGAKLTNIFST 180

Query: 595  EFVIETADGKRQRKYKQVFSNNMGTKTEPIISKCKAGENWTRITFKPDLVKFSMSYLEED 774
            EFVIETADGKR +KYKQVFSNNMGTK+EP+ISKCK+GENWT+ITFKPDL KFSMS LEED
Sbjct: 181  EFVIETADGKRLKKYKQVFSNNMGTKSEPVISKCKSGENWTKITFKPDLTKFSMSCLEED 240

Query: 775  VVALMKKRVIDVAGCLGKTVKVELNGQLFHFKSFSNYCDLYMKSTSVSTLDPLPRFEEEV 954
            VVALMKKRVID+AGCLGKTVKVELNGQ FHFKSFSNYCDLY+KS S+++ +PLPRFEEEV
Sbjct: 241  VVALMKKRVIDIAGCLGKTVKVELNGQQFHFKSFSNYCDLYLKSASLASSEPLPRFEEEV 300

Query: 955  HDRWQVCISRSEGQFQQVSFVNGIATVKGGTHVDYVTNKITSHLVSVIXXXXXXXXXFDL 1134
            HDRWQVC+SRSEGQFQQVSFVNGIAT+KGGTHVDYVTNKITSHLV+VI         FDL
Sbjct: 301  HDRWQVCVSRSEGQFQQVSFVNGIATIKGGTHVDYVTNKITSHLVAVIKNKNKKNKKFDL 360

Query: 1135 KPHTVKNHLWVFVNALIDNPAFDSQTKETLTLRAASFGSSWDFSSKFLDKVAKSDIMKNI 1314
            KPHTVKNHLWVFVNALIDNPAFDSQTKETLTLRA SFGSSWDFSSKFLDKV+KSDIMKNI
Sbjct: 361  KPHTVKNHLWVFVNALIDNPAFDSQTKETLTLRAGSFGSSWDFSSKFLDKVSKSDIMKNI 420

Query: 1315 EEWAEFKQKKDLKKTDGSKDRRIYGLAKLADANEAGGKNSEKCTLILTEGDSAKALAIAG 1494
            EEWAEFKQKKDLKKTDG+KDRRIYGL KLADANEAGGKNSEKCTLILTEGDSAKALAIAG
Sbjct: 421  EEWAEFKQKKDLKKTDGAKDRRIYGLTKLADANEAGGKNSEKCTLILTEGDSAKALAIAG 480

Query: 1495 LSVVGRDHYGVFPLRGKLLNVREASHNQLMQNVEIQHIKQILGLQHGKQYDSVKPLRYGH 1674
            +SVVGRDHYGVFPLRGKLLNVREASH QLMQNVEIQHIKQILGLQHGKQYDSVK LRYGH
Sbjct: 481  ISVVGRDHYGVFPLRGKLLNVREASHTQLMQNVEIQHIKQILGLQHGKQYDSVKSLRYGH 540

Query: 1675 LMIMTDQDHDGSHIKGLLINFIHSFWPSLLKVPTFLLEFITPIVKATHRDGKRKESFYTM 1854
            LMIMTDQDHDGSHIKGLLINFIHSFWPSLLKVP+F+LEFITPIVKAT++ GK K+SFYTM
Sbjct: 541  LMIMTDQDHDGSHIKGLLINFIHSFWPSLLKVPSFMLEFITPIVKATNKYGKNKKSFYTM 600

Query: 1855 PQYETWKQNQGTDVKNWTIKYYKGLGTSTDQEAKEYFEALGRHKKDFVWVDEQDGDAIEL 2034
            PQYE WK++ G+D KNWTIKYYKGLGTSTD+E KEYFE LG+HKKDFVWVDEQDGDAIEL
Sbjct: 601  PQYEAWKESIGSDAKNWTIKYYKGLGTSTDKEGKEYFEDLGKHKKDFVWVDEQDGDAIEL 660

Query: 2035 AFSKKKIEARKNWLRQFEPGTYLCDLEEHIKYRDFVHKELILFSIADLQRSIPSMVDGLK 2214
            AFSKKKIEARK+WLRQFEPGTYL D + HIKYRDFVHKELILFSIADLQRSIPSMVDGLK
Sbjct: 661  AFSKKKIEARKSWLRQFEPGTYLDDRDSHIKYRDFVHKELILFSIADLQRSIPSMVDGLK 720

Query: 2215 PGQRKILFCSFKRNFIKEAKVAQFSGYVSEHSAYHHGEQSLASTIIGMAQDYVGSNNINL 2394
            PGQRKIL+CSFKRNF+KEAKVAQFSGYVSEHSAYHHGEQSLASTIIGMAQDYVGSNNINL
Sbjct: 721  PGQRKILYCSFKRNFVKEAKVAQFSGYVSEHSAYHHGEQSLASTIIGMAQDYVGSNNINL 780

Query: 2395 LLPNGQFGTRGQGGKDHASARYIYTQLSSITRFLFPKADDFLLNYLNEDGQSIEPTWYVP 2574
            LLPNGQFGTRGQGGKDHASARY+YTQLS +TRFLFPKADD LL+YLNEDGQ IEPTWYVP
Sbjct: 781  LLPNGQFGTRGQGGKDHASARYVYTQLSPVTRFLFPKADDILLDYLNEDGQMIEPTWYVP 840

Query: 2575 TIPMVLVNGSEGIGTGWSTFIPNYNPLDIIANVRHLLNDEPMEPMHPWYKGFIGSIEKTA 2754
             IP VLVNGSEGIGTGWS+F+PNYNPLDIIANVRHLLN EPME MHPWYKGF G+IEKTA
Sbjct: 841  IIPTVLVNGSEGIGTGWSSFVPNYNPLDIIANVRHLLNGEPMEAMHPWYKGFKGTIEKTA 900

Query: 2755 TKEAGNSYTVSGIIEEVDETSLRITELPIRKWTQDYKEFLESVSAENDKSKDPFIEGCRD 2934
            TKEAG SYTV+GIIEEVDET+L ITELPIR+WTQDYKEFLES+SAENDKSKDPFIEGCRD
Sbjct: 901  TKEAGFSYTVTGIIEEVDETTLTITELPIRRWTQDYKEFLESISAENDKSKDPFIEGCRD 960

Query: 2935 NSGGEIVHFSVYMSPNNLSEAKQEGLMKKFKLTTSISTSNMHLFDSKGVIKKYDTPEQII 3114
            NSGGEI+HF+VY+S  NL  AKQEGL+KKFKLTT++STSNMHLFDSKGVIKKYD+PEQI+
Sbjct: 961  NSGGEIIHFAVYLSETNLLVAKQEGLLKKFKLTTTMSTSNMHLFDSKGVIKKYDSPEQIL 1020

Query: 3115 EEFFHIRLEFYDKRKKALLANLENDMLKCDNKYRFIRGVVDGSIIVSNRKRADLFLELKE 3294
            EEFF+IRLEFY+KRKKALLANLE DMLKCDNKYRFIRGVV+G+I+VSNRK+ADLFLELK 
Sbjct: 1021 EEFFYIRLEFYEKRKKALLANLELDMLKCDNKYRFIRGVVEGTIVVSNRKKADLFLELKA 1080

Query: 3295 KGFTPFPKKKTAAEIAIAGSTDDADESEENNDVAIGKGVSASDYDYLLSLAIGTLTAEKM 3474
            KGFTPFPKKK   E+A+AG+TDD +E+E+N +V I KGVSASDYDYLLSLAIGTLTAEK+
Sbjct: 1081 KGFTPFPKKKNTPEVAVAGATDDTEETEDNTEVEIAKGVSASDYDYLLSLAIGTLTAEKL 1140

Query: 3475 KELRDERDKLMQEVEELKRATVKSLWMHDLDALESKFIEELNKSEKKWAENRQRIL-GEA 3651
            +ELRDER++L QEVE+LK++TVKSLW  DLDALE+K IE+L  SEKKW E+RQRI  GE 
Sbjct: 1141 QELRDERERLTQEVEDLKKSTVKSLWTKDLDALEAKIIEDLKNSEKKWEEDRQRIQGGET 1200

Query: 3652 KGTRPVQTKPRKNTKKA-SNKESVVEQMEVSDNTVTETDKVGEVXXXXXXXXXXXXXXXX 3828
            K  RP+   PRKNTKKA + KES  E M+VSDNTVTETDKV E+                
Sbjct: 1201 KIARPLAKNPRKNTKKATTKKESTAEHMDVSDNTVTETDKVAEI-KKPRGKAAAAKKKAP 1259

Query: 3829 XXXXXXXXXXXXXXXXXXLRHRLAAYNFDSSPDRSEDMETEQPQMPTKKKEPNRRTAAQK 4008
                              LR R+AAYNFDSSPDR+EDMETE PQ+ TKKKEP +R A +K
Sbjct: 1260 VAKVVAEADEDDDDGVAELRQRIAAYNFDSSPDRAEDMETELPQLQTKKKEPTKRAAPRK 1319

Query: 4009 KPLSTVSETXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXTKPPLAGTKKRGQQANK 4188
            K +S VS+                                    KPP AG KKRG  + +
Sbjct: 1320 KQVSIVSDDEEDDDIEIIDDDDFEPEDKKKKGGRKPANPKAAAAKPP-AGAKKRGPASKQ 1378

Query: 4189 QQT--QKLITEVLKP---AENSPEKKVRKMRASPFNKKSSSILGR-TISVDXXXXXXXXX 4350
             Q   QKLITEVLKP   A++SPEKKVR+MRASPFNKKSSSILGR  I+VD         
Sbjct: 1379 SQLVGQKLITEVLKPTAAADDSPEKKVRRMRASPFNKKSSSILGRGAINVD--DDEDKEI 1436

Query: 4351 XXXNSVSTLGSVTEDVSQAVAPK-ARPQRGTRGNARY 4458
               ++     SV++DVS+ V P  +RP+R  R    Y
Sbjct: 1437 GETSNEQERSSVSDDVSKGVGPAVSRPKRVNRRQTSY 1473


>dbj|BAE06274.1| topoisomerase II [Scutellaria baicalensis]
          Length = 1469

 Score = 2225 bits (5765), Expect = 0.0
 Identities = 1131/1468 (77%), Positives = 1236/1468 (84%), Gaps = 4/1468 (0%)
 Frame = +1

Query: 67   MAGAKKAPLTTSNNANIPPSETVTAAGGKKTIEQTYQKKTQLEHILLRPDTYIGSIEKHT 246
            MAG KK PLTTSNNANIPP +     G KKTIEQ YQKKTQLEHILLRPDTYIGSIE+HT
Sbjct: 1    MAGGKKGPLTTSNNANIPPPDAA-GGGSKKTIEQAYQKKTQLEHILLRPDTYIGSIERHT 59

Query: 247  QTLWVYENEQMVQKSITFVPGLYKIFDEILVNAADNKQRDPKMDSVKVTIDVESSCISVY 426
            QTLWVYENEQMVQKSIT+VPGLYKIFDEILVNAADNKQRDPKM+SVKVTIDVES+CISVY
Sbjct: 60   QTLWVYENEQMVQKSITYVPGLYKIFDEILVNAADNKQRDPKMNSVKVTIDVESNCISVY 119

Query: 427  NNGDGVPVEIHQEEGVYVPELIFGHLLTSSNYDDNEKKTTGGRNGYGAKLTNIFSTEFVI 606
            NNGDGVPVEIHQEEGVYVPELIFGHLLTSSNYDDNEKKTTGGRNGYGAKLTNIFSTEFVI
Sbjct: 120  NNGDGVPVEIHQEEGVYVPELIFGHLLTSSNYDDNEKKTTGGRNGYGAKLTNIFSTEFVI 179

Query: 607  ETADGKRQRKYKQVFSNNMGTKTEPIISKCKAGENWTRITFKPDLVKFSMSYLEEDVVAL 786
            ETADGKR++KYKQVFSNNMGTK+EPIISK +AG++WT+ITFKPDL KF+M+ LE+D VAL
Sbjct: 180  ETADGKREKKYKQVFSNNMGTKSEPIISKRQAGDDWTKITFKPDLAKFNMTCLEDDTVAL 239

Query: 787  MKKRVIDVAGCLGKTVKVELNGQLFHFKSFSNYCDLYMKSTSVSTLDPLPRFEEEVHDRW 966
            MKKRVID+AGCLGKTVKVELNGQ FHFKSFS+YCDLYMKSTSVS+LDPLPRFEEEVH+RW
Sbjct: 240  MKKRVIDIAGCLGKTVKVELNGQKFHFKSFSSYCDLYMKSTSVSSLDPLPRFEEEVHERW 299

Query: 967  QVCISRSEGQFQQVSFVNGIATVKGGTHVDYVTNKITSHLVSVIXXXXXXXXXFDLKPHT 1146
            Q+ +SRSEGQFQQVSFVNGIAT+KGGTHVDYVTNKITSHLV+VI         FDLKPHT
Sbjct: 300  QIFVSRSEGQFQQVSFVNGIATIKGGTHVDYVTNKITSHLVNVIKNKNKKNKKFDLKPHT 359

Query: 1147 VKNHLWVFVNALIDNPAFDSQTKETLTLRAASFGSSWDFSSKFLDKVAKSDIMKNIEEWA 1326
            VKNHLWVFVNALIDNPAFDSQTKETLTLRAASFGSSWDFSS FLD+VAKSDIMKNIEEWA
Sbjct: 360  VKNHLWVFVNALIDNPAFDSQTKETLTLRAASFGSSWDFSSNFLDRVAKSDIMKNIEEWA 419

Query: 1327 EFKQKKDLKKTDGSKDRRIYGLAKLADANEAGGKNSEKCTLILTEGDSAKALAIAGLSVV 1506
            EFKQKKDLKKTDGSKDRRIYGLAKL+DANEAGG+NS+KCTLILTEGDSAKALAIAGLSVV
Sbjct: 420  EFKQKKDLKKTDGSKDRRIYGLAKLSDANEAGGRNSDKCTLILTEGDSAKALAIAGLSVV 479

Query: 1507 GRDHYGVFPLRGKLLNVREASHNQLMQNVEIQHIKQILGLQHGKQYDSVKPLRYGHLMIM 1686
            GRDHYGVFPLRGKLLNVREASHNQLM N+EIQHIKQILGLQHGKQY+SVKPLRYGHLMIM
Sbjct: 480  GRDHYGVFPLRGKLLNVREASHNQLMHNLEIQHIKQILGLQHGKQYESVKPLRYGHLMIM 539

Query: 1687 TDQDHDGSHIKGLLINFIHSFWPSLLKVPTFLLEFITPIVKATHRDGKRKESFYTMPQYE 1866
            TDQDHDGSHIKGLLINFIHSFWPSLLK+P+FLL FITPIVKA H+DGKRK SFYTMPQYE
Sbjct: 540  TDQDHDGSHIKGLLINFIHSFWPSLLKIPSFLLGFITPIVKARHKDGKRKLSFYTMPQYE 599

Query: 1867 TWKQNQGTDVKNWTIKYYKGLGTSTDQEAKEYFEALGRHKKDFVWVDEQDGDAIELAFSK 2046
             WK+ QGT+ KNWT+KYYKGLGTSTDQEA EYF  LG+H+KDFV+VD +D DAIELAFSK
Sbjct: 600  AWKEAQGTEAKNWTVKYYKGLGTSTDQEAMEYFSDLGKHEKDFVYVDGEDDDAIELAFSK 659

Query: 2047 KKIEARKNWLRQFEPGTYLCDLEEHIKYRDFVHKELILFSIADLQRSIPSMVDGLKPGQR 2226
            KKIEARK WLRQFEPGT+L D + HIKYRDFVHKELILFSIAD+QRSIPSMVDGLKPGQR
Sbjct: 660  KKIEARKGWLRQFEPGTFLDDRDSHIKYRDFVHKELILFSIADVQRSIPSMVDGLKPGQR 719

Query: 2227 KILFCSFKRNFIKEAKVAQFSGYVSEHSAYHHGEQSLASTIIGMAQDYVGSNNINLLLPN 2406
            KILFCSFKRNF++EAKVAQFSGYVSEHSAYHHGEQSLA TIIGMAQDYVGSNNINLLLP 
Sbjct: 720  KILFCSFKRNFVREAKVAQFSGYVSEHSAYHHGEQSLAGTIIGMAQDYVGSNNINLLLPI 779

Query: 2407 GQFGTRGQGGKDHASARYIYTQLSSITRFLFPKADDFLLNYLNEDGQSIEPTWYVPTIPM 2586
            GQFGTRGQGGKDHASARY++TQLS +TRFLFPKADD LL+YLNEDGQSIEPTWYVP IPM
Sbjct: 780  GQFGTRGQGGKDHASARYVFTQLSPVTRFLFPKADDILLDYLNEDGQSIEPTWYVPIIPM 839

Query: 2587 VLVNGSEGIGTGWSTFIPNYNPLDIIANVRHLLNDEPMEPMHPWYKGFIGSIEKTATKEA 2766
            VLVNGSEGIGTGWS+++PNYNP+DIIAN+RHLLNDE  EPMHPWYKGF+GS+EKTATKEA
Sbjct: 840  VLVNGSEGIGTGWSSYVPNYNPVDIIANIRHLLNDEATEPMHPWYKGFLGSVEKTATKEA 899

Query: 2767 GNSYTVSGIIEEVDETSLRITELPIRKWTQDYKEFLESVSAENDKSKDPFIEGCRDNSGG 2946
            G SYTVSGIIEEVD+T+L I ELPIR+WTQDYKEFLESVSAENDKSKDPFIEGCRD SG 
Sbjct: 900  GASYTVSGIIEEVDDTTLCIKELPIRRWTQDYKEFLESVSAENDKSKDPFIEGCRDYSGS 959

Query: 2947 EIVHFSVYMSPNNLSEAKQEGLMKKFKLTTSISTSNMHLFDSKGVIKKYDTPEQIIEEFF 3126
            E+V+F V M P  L  AK+EGL+KKFKLTTSIST NMHLFDSKGVIKKYDTPEQI+EEFF
Sbjct: 960  ELVNFLVGMKPEKLEAAKREGLLKKFKLTTSISTCNMHLFDSKGVIKKYDTPEQILEEFF 1019

Query: 3127 HIRLEFYDKRKKALLANLENDMLKCDNKYRFIRGVVDGSIIVSNRKRADLFLELKEKGFT 3306
            +IRLE Y+KRKK LL  LE+DMLKCDNKYRFIR VV+GSIIVSNRKR D+F ELKEKGFT
Sbjct: 1020 YIRLELYEKRKKVLLDILEHDMLKCDNKYRFIRCVVEGSIIVSNRKRTDVFRELKEKGFT 1079

Query: 3307 PFPKKKTAAEIAIAGSTDDADESEENNDVAIGKGVSASDYDYLLSLAIGTLTAEKMKELR 3486
            PFPKKK  AE+AIAG+TDD +E+EEN++V I  GVS+SDYDYLLSLAIGTLT EKM+ELR
Sbjct: 1080 PFPKKKNRAEVAIAGATDDGEETEENSEVPIAPGVSSSDYDYLLSLAIGTLTTEKMQELR 1139

Query: 3487 DERDKLMQEVEELKRATVKSLWMHDLDALESKFIEELNKSEKKWAENRQRILGEAKGTRP 3666
             ERDKLMQEVEELK++T +SLW  DLDALE K  EE    E+ W +N+++I G+      
Sbjct: 1140 AERDKLMQEVEELKQSTARSLWNKDLDALEDKLAEEQKIYEETWEKNKRKIHGKTDTLEI 1199

Query: 3667 VQTKPRKNTKKASNKESVVEQMEVSDNTVTETDKVGEVXXXXXXXXXXXXXXXXXXXXXX 3846
            +Q  PRKN KK + KES VE ME+S+NT TETD V                         
Sbjct: 1200 IQKNPRKN-KKTTKKESAVE-MEISENTTTETD-VKIKKPRGKAAAKKKEPAAKVVTAAP 1256

Query: 3847 XXXXXXXXXXXXLRHRLAAYNFDSSPDRSEDMETEQPQMPTKKKEPNRRTAAQKKPLSTV 4026
                        LR R+AAYNFDSSPD SEDM TE   + TK K+P RR AAQKK LS  
Sbjct: 1257 VEEQEDDDGIADLRQRIAAYNFDSSPDHSEDMATEVAPVQTKNKQPARRGAAQKKTLSAA 1316

Query: 4027 SETXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXTKPPLAGTKKRG---QQANKQQT 4197
            SET                                   K P A  KKRG   +Q+++   
Sbjct: 1317 SET------------DEDDDAFEPEEKKKKGGRKPAAAKAP-AAAKKRGPSAKQSSQLVG 1363

Query: 4198 QKLITEVLKP-AENSPEKKVRKMRASPFNKKSSSILGRTISVDXXXXXXXXXXXXNSVST 4374
            QKLITEVLKP A++SPEKKVR+MR SPFNKKSSSILG+TI++D               S 
Sbjct: 1364 QKLITEVLKPAADDSPEKKVRRMRESPFNKKSSSILGKTINID--------DDDEEETSG 1415

Query: 4375 LGSVTEDVSQAVAPKARPQRGTRGNARY 4458
              S+ E      A  ARP+R  RG A+Y
Sbjct: 1416 TSSMNEG-----AAAARPKRANRGKAKY 1438


>gb|KZV36276.1| DNA topoisomerase 2 [Dorcoceras hygrometricum]
          Length = 1455

 Score = 2162 bits (5603), Expect = 0.0
 Identities = 1102/1467 (75%), Positives = 1225/1467 (83%), Gaps = 3/1467 (0%)
 Frame = +1

Query: 67   MAGAKKAPLTTSNNANIPPSETVTAAGGKKTIEQTYQKKTQLEHILLRPDTYIGSIEKHT 246
            MA A+K PLTTSNN+NIPP     AA GKKTIE+TYQKKTQLEHIL+RPDTYIGSIEKH 
Sbjct: 1    MAAARKVPLTTSNNSNIPPQ---VAAAGKKTIEETYQKKTQLEHILIRPDTYIGSIEKHN 57

Query: 247  QTLWVYENEQMVQKSITFVPGLYKIFDEILVNAADNKQRDPKMDSVKVTIDVESSCISVY 426
            QTLWVYENEQMVQ+SI++VPGLYKIFDEILVNAADNKQRDPKMDSVK             
Sbjct: 58   QTLWVYENEQMVQRSISYVPGLYKIFDEILVNAADNKQRDPKMDSVK------------- 104

Query: 427  NNGDGVPVEIHQEEGVYVPELIFGHLLTSSNYDDNEKKTTGGRNGYGAKLTNIFSTEFVI 606
                        EEGVYVPELIFGHLLTSSNYDDNEKKTTGGRNGYGAKLTNIFSTEFVI
Sbjct: 105  ------------EEGVYVPELIFGHLLTSSNYDDNEKKTTGGRNGYGAKLTNIFSTEFVI 152

Query: 607  ETADGKRQRKYKQVFSNNMGTKTEPIISKCKAGENWTRITFKPDLVKFSMSYLEEDVVAL 786
            ETADGK Q+KYKQVFS+NMG K+EP+I+KCK+ ENWT+++FKPDL KFSM+YLEEDVVAL
Sbjct: 153  ETADGKSQKKYKQVFSDNMGKKSEPVITKCKSNENWTKVSFKPDLAKFSMTYLEEDVVAL 212

Query: 787  MKKRVIDVAGCLGKTVKVELNGQLFHFKSFSNYCDLYMKSTSVSTLDPLPRFEEEVHDRW 966
            MKKRVIDVAGCLGKTVKVELNG+LF+FKSFS+YC+LY+KS SVS+ D LPRFEEEVH+RW
Sbjct: 213  MKKRVIDVAGCLGKTVKVELNGKLFNFKSFSSYCELYLKSPSVSSSDLLPRFEEEVHERW 272

Query: 967  QVCISRSEGQFQQVSFVNGIATVKGGTHVDYVTNKITSHLVSVIXXXXXXXXXFDLKPHT 1146
            Q+C+SRSEGQFQQVSFVNGIATVKGGTHVDYVTNKIT HL++V+         FDLKPHT
Sbjct: 273  QICVSRSEGQFQQVSFVNGIATVKGGTHVDYVTNKITGHLINVLKNKNKKSKTFDLKPHT 332

Query: 1147 VKNHLWVFVNALIDNPAFDSQTKETLTLRAASFGSSWDFSSKFLDKVAKSDIMKNIEEWA 1326
            VKNHLW+FVNALIDNPAFDSQTKETLTLRA SFGSSW+F++KFLDKVAKSDIMKNIEEWA
Sbjct: 333  VKNHLWIFVNALIDNPAFDSQTKETLTLRAGSFGSSWEFTTKFLDKVAKSDIMKNIEEWA 392

Query: 1327 EFKQKKDLKKTDGSKDRRIYGLAKLADANEAGGKNSEKCTLILTEGDSAKALAIAGLSVV 1506
            EFKQKKDLKKTDGSKDRRIYGLAKLADANEAGGKNSEKCTLILTEGDSAKALAIAGL+VV
Sbjct: 393  EFKQKKDLKKTDGSKDRRIYGLAKLADANEAGGKNSEKCTLILTEGDSAKALAIAGLAVV 452

Query: 1507 GRDHYGVFPLRGKLLNVREASHNQLMQNVEIQHIKQILGLQHGKQYDSVKPLRYGHLMIM 1686
            GRDHYGVFPLRGKLLNVREASHNQLMQN+EIQ+IKQILGLQHGKQYDSVK LRYGHLMIM
Sbjct: 453  GRDHYGVFPLRGKLLNVREASHNQLMQNLEIQNIKQILGLQHGKQYDSVKSLRYGHLMIM 512

Query: 1687 TDQDHDGSHIKGLLINFIHSFWPSLLKVPTFLLEFITPIVKATHRDGKRKESFYTMPQYE 1866
            TDQDHDGSHIKGLLINFIHSFWPSLLKVP+F+LEFITPIVKAT R+G++K SFYTMPQYE
Sbjct: 513  TDQDHDGSHIKGLLINFIHSFWPSLLKVPSFMLEFITPIVKATQRNGEKK-SFYTMPQYE 571

Query: 1867 TWKQNQGTDVKNWTIKYYKGLGTSTDQEAKEYFEALGRHKKDFVWVDEQDGDAIELAFSK 2046
            +WK++ G + +NW+IKYYKGLGTST++EAKEYF  L  HKKDF+WVDEQDG+AIELAFSK
Sbjct: 572  SWKESLGENARNWSIKYYKGLGTSTNEEAKEYFGDLRMHKKDFLWVDEQDGEAIELAFSK 631

Query: 2047 KKIEARKNWLRQFEPGTYLCDLEEHIKYRDFVHKELILFSIADLQRSIPSMVDGLKPGQR 2226
            KKIEARK+WLRQFEPGTYL   E+ IKYRDFVHKELILFS+ADLQRSIPSMVDGLKPGQR
Sbjct: 632  KKIEARKSWLRQFEPGTYLDQREKLIKYRDFVHKELILFSMADLQRSIPSMVDGLKPGQR 691

Query: 2227 KILFCSFKRNFIKEAKVAQFSGYVSEHSAYHHGEQSLASTIIGMAQDYVGSNNINLLLPN 2406
            KILFCSFKRNFIKEAKV+QFSGYVSEHSAYHHGEQSLASTIIGMAQDYVGSNNINLL PN
Sbjct: 692  KILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDYVGSNNINLLKPN 751

Query: 2407 GQFGTRGQGGKDHASARYIYTQLSSITRFLFPKADDFLLNYLNEDGQSIEPTWYVPTIPM 2586
            GQFGTRGQGGKDHASARYI+TQLS +TRF+FPKADD LLNYLNEDGQ IEP+WYVP IPM
Sbjct: 752  GQFGTRGQGGKDHASARYIFTQLSPVTRFMFPKADDILLNYLNEDGQRIEPSWYVPIIPM 811

Query: 2587 VLVNGSEGIGTGWSTFIPNYNPLDIIANVRHLLNDEPMEPMHPWYKGFIGSIEKTATKEA 2766
            VLVNGSEGIGTGWS+F+PNYNP DIIANVRHLLNDE M+ MHPWY+GF G+IEKTATKEA
Sbjct: 812  VLVNGSEGIGTGWSSFVPNYNPKDIIANVRHLLNDEKMDAMHPWYRGFRGTIEKTATKEA 871

Query: 2767 GN-SYTVSGIIEEVDETSLRITELPIRKWTQDYKEFLESVSAENDKSKDPFIEGCRDNSG 2943
            G  SYT+SGIIEEVD+ +LRITELPIRKWTQDYKEFLESV+AEN+KSKDPFIEGC D+S 
Sbjct: 872  GGVSYTISGIIEEVDDATLRITELPIRKWTQDYKEFLESVAAENEKSKDPFIEGCSDHST 931

Query: 2944 GEIVHFSVYMSPNNLSEAKQEGLMKKFKLTTSISTSNMHLFDSKGVIKKYDTPEQIIEEF 3123
            G+IVHF V MS +NL +A+QEGL+KKFKLTTSISTSNMHLFDS G+IKKYDTPEQI+EEF
Sbjct: 932  GDIVHFLVCMSQDNLLQARQEGLLKKFKLTTSISTSNMHLFDSNGLIKKYDTPEQILEEF 991

Query: 3124 FHIRLEFYDKRKKALLANLENDMLKCDNKYRFIRGVVDGSIIVSNRKRADLFLELKEKGF 3303
            FHIRL+FY+KRKKALLANLEND+LKC+NKY+FIR VV+GSIIVSNRKRADLF ELKEKGF
Sbjct: 992  FHIRLDFYEKRKKALLANLENDLLKCENKYKFIRCVVEGSIIVSNRKRADLFRELKEKGF 1051

Query: 3304 TPFPKKKTAAEIAIAGSTDDADESEENNDVAIGKGVSASDYDYLLSLAIGTLTAEKMKEL 3483
            TPFPKKK++A++ IAGSTDDA+++ EN+  A G G S SDYDYLLS+AIGTLT EK++EL
Sbjct: 1052 TPFPKKKSSADVFIAGSTDDAEDTGENSPGATGSGDSTSDYDYLLSMAIGTLTLEKLQEL 1111

Query: 3484 RDERDKLMQEVEELKRATVKSLWMHDLDALESKFIEELNKSEKKWAENRQRILGEAKGTR 3663
            R ERDKL+QEVEELK +T+KSLW+ DLDALE K ++EL +SE+K    R++ILG+AK TR
Sbjct: 1112 RAERDKLLQEVEELKSSTIKSLWLSDLDALEGK-LDELEQSEEKIEVERKKILGKAKITR 1170

Query: 3664 PVQTKPRKNTKKASNKESVVEQMEVSDNTVTETDKVGEVXXXXXXXXXXXXXXXXXXXXX 3843
            PV   PRKN KK SNKES  E   +S N V ETD + E                      
Sbjct: 1171 PVLKNPRKNNKKTSNKES-AEPNGISVNPVPETDNIAE--NKKVKGKAPAKKKAPARKAA 1227

Query: 3844 XXXXXXXXXXXXXLRHRLAAYNFDSSPDRSEDMETEQPQMPTKKKEPNRRTAAQKKPLST 4023
                         LR RLA+YN DSSPD  EDMETE   +P K KEP++R AAQ K LS 
Sbjct: 1228 DSDDDDEYDGIAGLRQRLASYNLDSSPDHIEDMETE---VPKKNKEPSKRVAAQTKKLSA 1284

Query: 4024 VSETXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXTKPPLAGTKKRGQQANKQQT-- 4197
            VSET                                   KPP AGTKKRG  + + Q   
Sbjct: 1285 VSETLDDEDEILTIEDDDFEPEGKKTKAGKKPANGKATAKPP-AGTKKRGPISKQSQVLG 1343

Query: 4198 QKLITEVLKPAENSPEKKVRKMRASPFNKKSSSILGRTISVDXXXXXXXXXXXXNSVSTL 4377
            QKLIT+VLKP ENSP+KKVRKMRASPFNKKSSS+LGR I+++            NS S+L
Sbjct: 1344 QKLITDVLKPTENSPDKKVRKMRASPFNKKSSSVLGREITME---LEETSPEHENSSSSL 1400

Query: 4378 GSVTEDVSQAVAPKARPQRGTRGNARY 4458
                 D ++AV P+ RPQR  R    Y
Sbjct: 1401 TGNLGDNAEAVVPRTRPQRANRRQQTY 1427


>gb|EPS67102.1| hypothetical protein M569_07672 [Genlisea aurea]
          Length = 1440

 Score = 2029 bits (5258), Expect = 0.0
 Identities = 1035/1415 (73%), Positives = 1151/1415 (81%), Gaps = 5/1415 (0%)
 Frame = +1

Query: 67   MAGAKKAPLTTSNNANIPPSETVTAAGGKKTIEQTYQKKTQLEHILLRPDTYIGSIEKHT 246
            MAG KK     SN A +P  +     GGKKTIEQTYQKKTQ+EHILLRPDTYIGSIEKHT
Sbjct: 1    MAGGKKPLPDASNIAGLPYPDVAGVGGGKKTIEQTYQKKTQIEHILLRPDTYIGSIEKHT 60

Query: 247  QTLWVYENEQMVQKSITFVPGLYKIFDEILVNAADNKQRDPKMDSVKVTIDVESSCISVY 426
            QTLWVY+N+ MV K+I +VPGLYKIFDEILVNAADNKQRDPKM+SVKVTIDVES+CIS+Y
Sbjct: 61   QTLWVYQNDAMVLKTINYVPGLYKIFDEILVNAADNKQRDPKMNSVKVTIDVESNCISIY 120

Query: 427  NNGDGVPVEIHQEEGVYVPELIFGHLLTSSNYDDNEKKTTGGRNGYGAKLTNIFSTEFVI 606
            NNGDGVPVEIHQ+EGVYVPELIFGHLLTSSNYDD+EKKTTGGRNGYGAKLTNIFSTEFV+
Sbjct: 121  NNGDGVPVEIHQDEGVYVPELIFGHLLTSSNYDDDEKKTTGGRNGYGAKLTNIFSTEFVV 180

Query: 607  ETADGKRQRKYKQVFSNNMGTKTEPIISKCKAGENWTRITFKPDLVKFSMSYLEEDVVAL 786
            ETADGKRQ+KYKQVFS+NM TK++P I+KC+A ENWT+ITFKPDL KFSM++LEEDVV+L
Sbjct: 181  ETADGKRQKKYKQVFSDNMATKSKPSITKCRASENWTKITFKPDLAKFSMTFLEEDVVSL 240

Query: 787  MKKRVIDVAGCLGKTVKVELNGQLFHFKSFSNYCDLYMKSTSVSTLDPLPRFEEEVHDRW 966
            MKKRVID+AGCLGKTVKVELNGQLF+FKSFSNYCDLY++S +V +  PLPRFEEEVH+RW
Sbjct: 241  MKKRVIDLAGCLGKTVKVELNGQLFNFKSFSNYCDLYLRSNAVPSNAPLPRFEEEVHERW 300

Query: 967  QVCISRSEGQFQQVSFVNGIATVKGGTHVDYVTNKITSHLVSVIXXXXXXXXXFDLKPHT 1146
            QVCISRSEGQFQQVSFVN IATVKGGTHVDYVTNKITSHL++V+          DLKPHT
Sbjct: 301  QVCISRSEGQFQQVSFVNSIATVKGGTHVDYVTNKITSHLITVMKNKNKKNKKIDLKPHT 360

Query: 1147 VKNHLWVFVNALIDNPAFDSQTKETLTLRAASFGSSWDFSSKFLDKVAKSDIMKNIEEWA 1326
            VKNHLWVFVNALIDNPAFDSQTKETLTLR +SFGSSWDFSSKFLDKVAKSDIMKNIEEWA
Sbjct: 361  VKNHLWVFVNALIDNPAFDSQTKETLTLRVSSFGSSWDFSSKFLDKVAKSDIMKNIEEWA 420

Query: 1327 EFKQKKDLKKTDGSKDRRIYGLAKLADANEAGGKNSEKCTLILTEGDSAKALAIAGLSVV 1506
            EFKQKKDLKKTDGSKDRRIYGL KL+DANEAGG+NSEKCTLILTEGDSAKALAIAGLSVV
Sbjct: 421  EFKQKKDLKKTDGSKDRRIYGLTKLSDANEAGGRNSEKCTLILTEGDSAKALAIAGLSVV 480

Query: 1507 GRDHYGVFPLRGKLLNVREASHNQLMQNVEIQHIKQILGLQHGKQYDSVKPLRYGHLMIM 1686
            GRDHYGVFPLRGKLLNVREASH QLM N EIQHIKQILGLQHGK YDSVK LRYGHLMIM
Sbjct: 481  GRDHYGVFPLRGKLLNVREASHTQLMNNAEIQHIKQILGLQHGKNYDSVKSLRYGHLMIM 540

Query: 1687 TDQDHDGSHIKGLLINFIHSFWPSLLKVPTFLLEFITPIVKATHRDGKRKESFYTMPQYE 1866
            TDQDHDGSHIKGLLINFIHSFWPSLLKVP+F+LEFITPIVKATH+  K +++FYTMP+YE
Sbjct: 541  TDQDHDGSHIKGLLINFIHSFWPSLLKVPSFMLEFITPIVKATHKITKIRKAFYTMPEYE 600

Query: 1867 TWKQNQGTDVKNWTIKYYKGLGTSTDQEAKEYFEALGRHKKDFVWVDEQDGDAIELAFSK 2046
             WKQN G D +NW+IKYYK   + TD E KEYFE L +HKKDFVWVDE+DGDAIELAFSK
Sbjct: 601  GWKQNLGPDSRNWSIKYYK--ASCTDAEGKEYFEDLSKHKKDFVWVDEEDGDAIELAFSK 658

Query: 2047 KKIEARKNWLRQFEPGTYLCDLEEHIKYRDFVHKELILFSIADLQRSIPSMVDGLKPGQR 2226
            KKIEARKNWLRQFEPGT+L   E+HIKYRDFVHKELILFS+ADLQRSIPSMVDGLKPGQR
Sbjct: 659  KKIEARKNWLRQFEPGTFLSQKEKHIKYRDFVHKELILFSVADLQRSIPSMVDGLKPGQR 718

Query: 2227 KILFCSFKRNFIKEAKVAQFSGYVSEHSAYHHGEQSLASTIIGMAQDYVGSNNINLLLPN 2406
            KILFCSFKRNF+KEAKVAQFSGYVSEHSAYHHGEQSLASTIIGMAQD+VGSNNINLLLPN
Sbjct: 719  KILFCSFKRNFVKEAKVAQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPN 778

Query: 2407 GQFGTRGQGGKDHASARYIYTQLSSITRFLFPKADDFLLNYLNEDGQSIEPTWYVPTIPM 2586
            GQFGTR QGGKDHASARYIYTQLS  TR+LFPKADD LL+YLNEDGQSIEP WY+P IPM
Sbjct: 779  GQFGTRDQGGKDHASARYIYTQLSPATRYLFPKADDVLLDYLNEDGQSIEPIWYMPIIPM 838

Query: 2587 VLVNGSEGIGTGWSTFIPNYNPLDIIANVRHLLNDEPMEPMHPWYKGFIGSIEKTATKEA 2766
            VLVNGSEGIGTGWSTFIPNYNP DIIANVRHLLNDE M+ M PWY+GF GSIEK  TKEA
Sbjct: 839  VLVNGSEGIGTGWSTFIPNYNPRDIIANVRHLLNDEMMDSMQPWYRGFRGSIEKNTTKEA 898

Query: 2767 GNSYTVSGIIEEVDETSLRITELPIRKWTQDYKEFLESVSAENDKSKDPFIEGCRDNSGG 2946
            G  Y VSGIIEE+DET+L++TELPIRKWTQDYKEFLESVS+ENDKSKDPFIEGC D S  
Sbjct: 899  GTGYNVSGIIEEIDETTLKVTELPIRKWTQDYKEFLESVSSENDKSKDPFIEGCSDYSSP 958

Query: 2947 EIVHFSVYMSPNNLSEAKQEGLMKKFKLTTSISTSNMHLFDSKGVIKKYDTPEQIIEEFF 3126
             I  F VYMS   L   KQEGL+KKFK+TT+I T+NMHLFD KGVIKKYDTPEQI+EEF+
Sbjct: 959  HIPQFMVYMSAEKLLAVKQEGLLKKFKMTTNIGTTNMHLFDPKGVIKKYDTPEQILEEFY 1018

Query: 3127 HIRLEFYDKRKKALLANLENDMLKCDNKYRFIRGVVDGSIIVSNRKRADLFLELKEKGFT 3306
            H+RLE+Y+KRKKALLANLE D+LKC+NK+RFIR VVDGSI+VSNRKRADL LELK+KGFT
Sbjct: 1019 HLRLEYYEKRKKALLANLEVDLLKCENKWRFIRCVVDGSIVVSNRKRADLLLELKQKGFT 1078

Query: 3307 PFPKKKTAAEIAIAGSTDDADESEENNDVAIGKGVSASDYDYLLSLAIGTLTAEKMKELR 3486
            PFPKKK AAE+ +AGSTDD  E+EEN   A  +G    DYDYLLSL+IGTLT EKM+EL 
Sbjct: 1079 PFPKKKLAAEVDVAGSTDDVYEAEENGATASHEG----DYDYLLSLSIGTLTVEKMRELE 1134

Query: 3487 DERDKLMQEVEELKRATVKSLWMHDLDALESKFIEELNKSEKKWAENRQRILGEAKGTRP 3666
             ERDKL+QE E+LKRA+VKSLWM DLDALE K ++EL K+ ++  ++R +++  AK  RP
Sbjct: 1135 AERDKLLQEFEDLKRASVKSLWMKDLDALEGK-LDELEKNAEEQEKSRSKVMNNAKLKRP 1193

Query: 3667 VQTKPRKNTKKASNK-ESVVEQM--EVSDNTVTETDKVGEVXXXXXXXXXXXXXXXXXXX 3837
            V   PRKN + A+ K +S   Q+  ++SDN   +T K  E                    
Sbjct: 1194 VLKNPRKNKEVANGKAKSAANQVTKQISDN--ADTFKKAEA---KASASKTSDLLHVIVL 1248

Query: 3838 XXXXXXXXXXXXXXXLRHRLAAYNFDSSPDRSEDMETEQPQMPTKKKEPNRRTAAQKKPL 4017
                           +  R+ AYN DSS       E        K  + N   A +K+  
Sbjct: 1249 TAYLQATVGDESGDEIVDRIPAYNVDSSHGVEAGTE--------KNDQSNGGGAVKKRKA 1300

Query: 4018 STVSETXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXTKPPLAGTKKRGQQANKQQT 4197
            S V E                                    K   +GTKKRG  +  QQ 
Sbjct: 1301 SDVVE-------------RVEKKRKKGSSSSSNTERPANANKEASSGTKKRGPSSGMQQL 1347

Query: 4198 --QKLITEVLKPAENSPEKKVRKMRASPFNKKSSS 4296
              QKLIT+VL+     PEKKVRK+  SPF K +++
Sbjct: 1348 RGQKLITDVLQ-----PEKKVRKLSESPFEKSNAA 1377


>gb|EPS73185.1| hypothetical protein M569_01571, partial [Genlisea aurea]
          Length = 1258

 Score = 2009 bits (5206), Expect = 0.0
 Identities = 980/1239 (79%), Positives = 1094/1239 (88%), Gaps = 2/1239 (0%)
 Frame = +1

Query: 67   MAGAKKAPLTTSNNANIPPSETVTAAGGKKTIEQTYQKKTQLEHILLRPDTYIGSIEKHT 246
            MAGAKK PLT+ NNANIPP ET  A G KKTIEQTYQKKTQLEHILLRPDTYIGS+EKHT
Sbjct: 1    MAGAKKIPLTSGNNANIPPPET-DAVGAKKTIEQTYQKKTQLEHILLRPDTYIGSVEKHT 59

Query: 247  QTLWVYENEQMVQKSITFVPGLYKIFDEILVNAADNKQRDPKMDSVKVTIDVESSCISVY 426
            QTLW+YEN  M  K+I++VPGLYKIFDEILVNAADNKQRDPKMDSVKVTIDVE++ IS+Y
Sbjct: 60   QTLWIYENNSMTLKNISYVPGLYKIFDEILVNAADNKQRDPKMDSVKVTIDVENNMISIY 119

Query: 427  NNGDGVPVEIHQEEGVYVPELIFGHLLTSSNYDDNEKKTTGGRNGYGAKLTNIFSTEFVI 606
            NNGDGVPVEIHQEEGVYVPE+IFGHLLTSSNYDDNEKKTTGGRNGYGAKLTNIFSTEF++
Sbjct: 120  NNGDGVPVEIHQEEGVYVPEMIFGHLLTSSNYDDNEKKTTGGRNGYGAKLTNIFSTEFIV 179

Query: 607  ETADGKRQRKYKQVFSNNMGTKTEPIISKCKAGENWTRITFKPDLVKFSMSYLEEDVVAL 786
            ETADG+RQ+ YKQVFSNNM TK+EP+ISKCKA ENWT+I FKPDL KFSMS LE+DVV+L
Sbjct: 180  ETADGRRQKSYKQVFSNNMSTKSEPVISKCKASENWTKIIFKPDLAKFSMSCLEDDVVSL 239

Query: 787  MKKRVIDVAGCLGKTVKVELNGQLFHFKSFSNYCDLYMKST--SVSTLDPLPRFEEEVHD 960
            MKKRVID+AGCLGKTV VELNG+LF+FK+FS+YC+LY+K++  S S+ +PLPRFEEEVH+
Sbjct: 240  MKKRVIDIAGCLGKTVNVELNGELFNFKTFSSYCELYLKTSMMSPSSSEPLPRFEEEVHE 299

Query: 961  RWQVCISRSEGQFQQVSFVNGIATVKGGTHVDYVTNKITSHLVSVIXXXXXXXXXFDLKP 1140
            RWQ+CISRSEGQFQQVSFVN I+TVKGGTHVDYVTNKIT+HL++VI         FD+KP
Sbjct: 300  RWQICISRSEGQFQQVSFVNSISTVKGGTHVDYVTNKITNHLLAVIKNKHKKNKKFDIKP 359

Query: 1141 HTVKNHLWVFVNALIDNPAFDSQTKETLTLRAASFGSSWDFSSKFLDKVAKSDIMKNIEE 1320
            H VKNHLWVFVNALIDNPAFDSQTKETLTLRA SFGSSWDFSSKFLD+VAKSDIM+NIE+
Sbjct: 360  HAVKNHLWVFVNALIDNPAFDSQTKETLTLRATSFGSSWDFSSKFLDRVAKSDIMRNIED 419

Query: 1321 WAEFKQKKDLKKTDGSKDRRIYGLAKLADANEAGGKNSEKCTLILTEGDSAKALAIAGLS 1500
            WA+FKQKKDLKKTDGSKDRRIYGL KLADANEAGGKNSEKCTLILTEGDSAKALA+AGLS
Sbjct: 420  WADFKQKKDLKKTDGSKDRRIYGLTKLADANEAGGKNSEKCTLILTEGDSAKALAMAGLS 479

Query: 1501 VVGRDHYGVFPLRGKLLNVREASHNQLMQNVEIQHIKQILGLQHGKQYDSVKPLRYGHLM 1680
            VVGRDHYGVFPLRGKLLNVREASH QLM N EIQHIKQILGLQHGK YDS K LRYGHLM
Sbjct: 480  VVGRDHYGVFPLRGKLLNVREASHTQLMNNAEIQHIKQILGLQHGKNYDSAKSLRYGHLM 539

Query: 1681 IMTDQDHDGSHIKGLLINFIHSFWPSLLKVPTFLLEFITPIVKATHRDGKRKESFYTMPQ 1860
            IMTDQDHDGSHIKGLLINFIHSFWPSLLK+P+F+LEFITPIVKATH+  K +++FYTMP+
Sbjct: 540  IMTDQDHDGSHIKGLLINFIHSFWPSLLKIPSFMLEFITPIVKATHKPTKTRKAFYTMPE 599

Query: 1861 YETWKQNQGTDVKNWTIKYYKGLGTSTDQEAKEYFEALGRHKKDFVWVDEQDGDAIELAF 2040
            YE WKQN G+D +NW+IKYYKGLGTSTD EAKEYFE LG+HKKDFVW +++DG+AIELAF
Sbjct: 600  YEEWKQNLGSDSRNWSIKYYKGLGTSTDAEAKEYFEDLGKHKKDFVWGNDEDGEAIELAF 659

Query: 2041 SKKKIEARKNWLRQFEPGTYLCDLEEHIKYRDFVHKELILFSIADLQRSIPSMVDGLKPG 2220
            SKKKIEARKNWLRQFEPGTYL  +E+ IKY DFVHKELILFS+ADLQRSIPSM+DGLKPG
Sbjct: 660  SKKKIEARKNWLRQFEPGTYLDQMEKKIKYSDFVHKELILFSVADLQRSIPSMIDGLKPG 719

Query: 2221 QRKILFCSFKRNFIKEAKVAQFSGYVSEHSAYHHGEQSLASTIIGMAQDYVGSNNINLLL 2400
            QRKILFCSFKRNF+KEAKVAQFSGYVSEHSAYHHGEQSLA TIIGMAQD+VGSNNINLLL
Sbjct: 720  QRKILFCSFKRNFVKEAKVAQFSGYVSEHSAYHHGEQSLAGTIIGMAQDFVGSNNINLLL 779

Query: 2401 PNGQFGTRGQGGKDHASARYIYTQLSSITRFLFPKADDFLLNYLNEDGQSIEPTWYVPTI 2580
            PNGQFGTR QGGKDHASARYI+TQL+ +TRFLFPKADD LL+YLNEDGQSIEPTWY+P I
Sbjct: 780  PNGQFGTRDQGGKDHASARYIFTQLNPVTRFLFPKADDILLDYLNEDGQSIEPTWYMPII 839

Query: 2581 PMVLVNGSEGIGTGWSTFIPNYNPLDIIANVRHLLNDEPMEPMHPWYKGFIGSIEKTATK 2760
            PM LVNGS+GIGTGWST IPNYNP DIIANVRHLLNDE M+PM PWY+G+ GSIEK+ATK
Sbjct: 840  PMALVNGSDGIGTGWSTSIPNYNPRDIIANVRHLLNDEMMDPMTPWYRGYRGSIEKSATK 899

Query: 2761 EAGNSYTVSGIIEEVDETSLRITELPIRKWTQDYKEFLESVSAENDKSKDPFIEGCRDNS 2940
            E    YTV+GIIEEVDET+LRITELP+RKWTQDYKEFLESVSAENDKSKDPF++GC D+S
Sbjct: 900  EL--VYTVTGIIEEVDETTLRITELPVRKWTQDYKEFLESVSAENDKSKDPFVQGCSDHS 957

Query: 2941 GGEIVHFSVYMSPNNLSEAKQEGLMKKFKLTTSISTSNMHLFDSKGVIKKYDTPEQIIEE 3120
              +  HF VYM+  NL  AKQE L+KKFKLT +I T+NMHLFD  G IKKYDTPEQI+EE
Sbjct: 958  SPQFAHFMVYMTAENLLAAKQENLLKKFKLTANICTTNMHLFDRNGAIKKYDTPEQILEE 1017

Query: 3121 FFHIRLEFYDKRKKALLANLENDMLKCDNKYRFIRGVVDGSIIVSNRKRADLFLELKEKG 3300
            FFHIRLE+Y+KRK  LLANLE D+LKC+NK+RFI+ VVDGSI+VSNRK+ADLFLELK KG
Sbjct: 1018 FFHIRLEYYEKRKATLLANLEIDLLKCENKWRFIKSVVDGSIVVSNRKKADLFLELKNKG 1077

Query: 3301 FTPFPKKKTAAEIAIAGSTDDADESEENNDVAIGKGVSASDYDYLLSLAIGTLTAEKMKE 3480
            FTPFPKKK AAE+   GST+D DE+EEN+ V   +  S  DYDYLLSLAIGTLT EKM E
Sbjct: 1078 FTPFPKKKQAAEVDFVGSTEDLDENEENDGVKTSQEGSIGDYDYLLSLAIGTLTVEKMDE 1137

Query: 3481 LRDERDKLMQEVEELKRATVKSLWMHDLDALESKFIEELNKSEKKWAENRQRILGEAKGT 3660
            LR ERDKL  + E+LKRATVKSLW+ DLDALE K ++EL K++ +  +NR   +G  K +
Sbjct: 1138 LRSERDKLSSDFEDLKRATVKSLWIKDLDALEEK-LDELEKADVEKEKNRSNAVGNTKVS 1196

Query: 3661 RPVQTKPRKNTKKASNKESVVEQMEVSDNTVTETDKVGE 3777
            + V   PRKN K A+     VE M    N   E + V +
Sbjct: 1197 KLVLKNPRKNNKAANTNVESVENMRCFVNVKCERNVVSK 1235


>gb|PIN08559.1| DNA topoisomerase type II [Handroanthus impetiginosus]
          Length = 1032

 Score = 1947 bits (5045), Expect = 0.0
 Identities = 956/1032 (92%), Positives = 988/1032 (95%), Gaps = 1/1032 (0%)
 Frame = +1

Query: 67   MAGAKKAPLTTSNNANIPPSETVTA-AGGKKTIEQTYQKKTQLEHILLRPDTYIGSIEKH 243
            MAGAKKAPLTTSNNANI P E  TA   GKKTIEQTYQKKTQLEHILLRPDTYIGSIEKH
Sbjct: 1    MAGAKKAPLTTSNNANIQPPEAATAPVAGKKTIEQTYQKKTQLEHILLRPDTYIGSIEKH 60

Query: 244  TQTLWVYENEQMVQKSITFVPGLYKIFDEILVNAADNKQRDPKMDSVKVTIDVESSCISV 423
            TQTLWVYENEQMVQ+SIT+VPGLYKIFDEILVNAADNKQRDPKMDSVKVTIDVES+CISV
Sbjct: 61   TQTLWVYENEQMVQRSITYVPGLYKIFDEILVNAADNKQRDPKMDSVKVTIDVESNCISV 120

Query: 424  YNNGDGVPVEIHQEEGVYVPELIFGHLLTSSNYDDNEKKTTGGRNGYGAKLTNIFSTEFV 603
            YNNGDGVPVEIH+EEGVYVPELIFGHLLTSSNYDDNEKKTTGGRNGYGAKLTNIFSTEFV
Sbjct: 121  YNNGDGVPVEIHEEEGVYVPELIFGHLLTSSNYDDNEKKTTGGRNGYGAKLTNIFSTEFV 180

Query: 604  IETADGKRQRKYKQVFSNNMGTKTEPIISKCKAGENWTRITFKPDLVKFSMSYLEEDVVA 783
            IETADGKR RKYKQVFSNNMGTK+EP+ISKCKAGENWT+ITFKPDL KFSM+YLEEDVVA
Sbjct: 181  IETADGKRHRKYKQVFSNNMGTKSEPVISKCKAGENWTKITFKPDLAKFSMTYLEEDVVA 240

Query: 784  LMKKRVIDVAGCLGKTVKVELNGQLFHFKSFSNYCDLYMKSTSVSTLDPLPRFEEEVHDR 963
            LMKKRVIDVAGCLGKTVKVELNGQLF FKSFSNYCDLY+KSTSVS+LDPLPRFEEEVH+R
Sbjct: 241  LMKKRVIDVAGCLGKTVKVELNGQLFQFKSFSNYCDLYLKSTSVSSLDPLPRFEEEVHER 300

Query: 964  WQVCISRSEGQFQQVSFVNGIATVKGGTHVDYVTNKITSHLVSVIXXXXXXXXXFDLKPH 1143
            WQ+CISRSEGQFQQVSFVNGIAT+KGGTHVDYVTNKITSHLV+VI         FDLKPH
Sbjct: 301  WQICISRSEGQFQQVSFVNGIATIKGGTHVDYVTNKITSHLVNVIKNKNKKNKKFDLKPH 360

Query: 1144 TVKNHLWVFVNALIDNPAFDSQTKETLTLRAASFGSSWDFSSKFLDKVAKSDIMKNIEEW 1323
            TVKNHLWVFVNALIDNPAFDSQTKETLTLRAASFGSSWDFS+KFLDKVAKSDIMKNIEEW
Sbjct: 361  TVKNHLWVFVNALIDNPAFDSQTKETLTLRAASFGSSWDFSTKFLDKVAKSDIMKNIEEW 420

Query: 1324 AEFKQKKDLKKTDGSKDRRIYGLAKLADANEAGGKNSEKCTLILTEGDSAKALAIAGLSV 1503
            AEFKQKKDLKKTDGSKDRRIYGLAKLADANEAGG+NSEKCTLILTEGDSAKALAIAGLSV
Sbjct: 421  AEFKQKKDLKKTDGSKDRRIYGLAKLADANEAGGRNSEKCTLILTEGDSAKALAIAGLSV 480

Query: 1504 VGRDHYGVFPLRGKLLNVREASHNQLMQNVEIQHIKQILGLQHGKQYDSVKPLRYGHLMI 1683
            VGRDHYGVFPL GKLLNVREASHNQLMQNVEIQHIKQILGLQHGKQYDS+K LRYGHLMI
Sbjct: 481  VGRDHYGVFPLSGKLLNVREASHNQLMQNVEIQHIKQILGLQHGKQYDSIKSLRYGHLMI 540

Query: 1684 MTDQDHDGSHIKGLLINFIHSFWPSLLKVPTFLLEFITPIVKATHRDGKRKESFYTMPQY 1863
            MTDQDHDGSHIKGLLINFIHSFWPSLLKVP+FLLEFITPIVKATH+DGKRK SFYTMPQY
Sbjct: 541  MTDQDHDGSHIKGLLINFIHSFWPSLLKVPSFLLEFITPIVKATHKDGKRKISFYTMPQY 600

Query: 1864 ETWKQNQGTDVKNWTIKYYKGLGTSTDQEAKEYFEALGRHKKDFVWVDEQDGDAIELAFS 2043
            E WKQNQGT+ KNWTIKYYKGLGTSTDQE KEYF+ LG+HKKDFVWVDEQDG+AIELAFS
Sbjct: 601  EEWKQNQGTEAKNWTIKYYKGLGTSTDQEGKEYFQDLGKHKKDFVWVDEQDGEAIELAFS 660

Query: 2044 KKKIEARKNWLRQFEPGTYLCDLEEHIKYRDFVHKELILFSIADLQRSIPSMVDGLKPGQ 2223
            KKKIEARK WLRQFEPGTYL D E HIKYRDFVHKELILFSIADLQRSIPSMVDGLKPGQ
Sbjct: 661  KKKIEARKTWLRQFEPGTYLDDQETHIKYRDFVHKELILFSIADLQRSIPSMVDGLKPGQ 720

Query: 2224 RKILFCSFKRNFIKEAKVAQFSGYVSEHSAYHHGEQSLASTIIGMAQDYVGSNNINLLLP 2403
            RKILFCSFKRNFIKEAKVAQFSGYVSEHSAYHHGEQSLASTIIGMAQDYVGSNNINLLLP
Sbjct: 721  RKILFCSFKRNFIKEAKVAQFSGYVSEHSAYHHGEQSLASTIIGMAQDYVGSNNINLLLP 780

Query: 2404 NGQFGTRGQGGKDHASARYIYTQLSSITRFLFPKADDFLLNYLNEDGQSIEPTWYVPTIP 2583
            NGQFGTRGQGGKDHASARYIYTQLS ITRFLFPKADD LLNYLNEDGQ IEPTWYVP IP
Sbjct: 781  NGQFGTRGQGGKDHASARYIYTQLSPITRFLFPKADDILLNYLNEDGQMIEPTWYVPIIP 840

Query: 2584 MVLVNGSEGIGTGWSTFIPNYNPLDIIANVRHLLNDEPMEPMHPWYKGFIGSIEKTATKE 2763
            MVLVNGSEGIGTGWS++IPNYNPLDIIANVRHLLNDEPMEPMHPWY+GF GSIEKTA KE
Sbjct: 841  MVLVNGSEGIGTGWSSYIPNYNPLDIIANVRHLLNDEPMEPMHPWYRGFRGSIEKTAGKE 900

Query: 2764 AGNSYTVSGIIEEVDETSLRITELPIRKWTQDYKEFLESVSAENDKSKDPFIEGCRDNSG 2943
            AGNSYTVSG I EVDET+LRITELPIRKWTQDYKEFLESVSAENDKSKDPFIE CR+NSG
Sbjct: 901  AGNSYTVSGNIGEVDETTLRITELPIRKWTQDYKEFLESVSAENDKSKDPFIESCRENSG 960

Query: 2944 GEIVHFSVYMSPNNLSEAKQEGLMKKFKLTTSISTSNMHLFDSKGVIKKYDTPEQIIEEF 3123
            GEIVHF VYM+  NL  AKQEGL+KKFKLTTSISTSNMHLFDSKGVIKKYDTPEQI+EEF
Sbjct: 961  GEIVHFVVYMTAENLLIAKQEGLLKKFKLTTSISTSNMHLFDSKGVIKKYDTPEQILEEF 1020

Query: 3124 FHIRLEFYDKRK 3159
            FHIRLEFY+KRK
Sbjct: 1021 FHIRLEFYEKRK 1032


>ref|XP_010241214.1| PREDICTED: DNA topoisomerase 2-like isoform X2 [Nelumbo nucifera]
          Length = 1503

 Score = 1937 bits (5018), Expect = 0.0
 Identities = 994/1487 (66%), Positives = 1161/1487 (78%), Gaps = 23/1487 (1%)
 Frame = +1

Query: 67   MAGAKKAPLTTSNNANIPPSETVTAAGGKKTIEQTYQKKTQLEHILLRPDTYIGSIEKHT 246
            MA  +K PL TSN AN+P S  +  +G  KTIE+TYQKK+QLEHILLRPDTY+GSIEKHT
Sbjct: 1    MALERKLPLQTSNIANVPSSRPLVGSG--KTIEETYQKKSQLEHILLRPDTYVGSIEKHT 58

Query: 247  QTLWVYENEQMVQKSITFVPGLYKIFDEILVNAADNKQRDPKMDSVKVTIDVESSCISVY 426
            QTLWVY+  +MV + +T+VPGLYKIFDEILVNAADNKQRDP MDSVKV ID E +CISVY
Sbjct: 59   QTLWVYDGGEMVHRPVTYVPGLYKIFDEILVNAADNKQRDPSMDSVKVVIDAEQNCISVY 118

Query: 427  NNGDGVPVEIHQEEGVYVPELIFGHLLTSSNYDDNEKKTTGGRNGYGAKLTNIFSTEFVI 606
            NNGDGVPVEIHQEEGVYVPELIFGHLLTSSNYDD  KKTTGGRNGYGAKLTNIFSTEF+I
Sbjct: 119  NNGDGVPVEIHQEEGVYVPELIFGHLLTSSNYDDTVKKTTGGRNGYGAKLTNIFSTEFII 178

Query: 607  ETADGKRQRKYKQVFSNNMGTKTEPIISKCKAGENWTRITFKPDLVKFSMSYLEEDVVAL 786
            ETADGKRQ+KYKQVFSNNMG K+EP I+KCK  ENWT++TFKPDL KF++++LE+DVVAL
Sbjct: 179  ETADGKRQKKYKQVFSNNMGKKSEPAITKCKGSENWTKVTFKPDLAKFNLTHLEDDVVAL 238

Query: 787  MKKRVIDVAGCLGKTVKVELNGQLFHFKSFSNYCDLYMKSTSVSTLDPLPRFEEEVHDRW 966
            MKKRVID+AGCLGKTVKVELNGQ    KSF +Y +LY++S S S  +PLPR  E+V +RW
Sbjct: 239  MKKRVIDLAGCLGKTVKVELNGQRVPVKSFLDYVNLYLQSASKSRPEPLPRITEKVSERW 298

Query: 967  QVCISRSEGQFQQVSFVNGIATVKGGTHVDYVTNKITSHLVSVIXXXXXXXXXFDLKPHT 1146
            +VC+S SEGQFQQVSFVNGIAT+KGGTHVDYVTN+IT+H+++++          +LK HT
Sbjct: 299  EVCVSLSEGQFQQVSFVNGIATIKGGTHVDYVTNQITNHVMTIVNKKNKNA---NLKAHT 355

Query: 1147 VKNHLWVFVNALIDNPAFDSQTKETLTLRAASFGSSWDFSSKFLDKVAKSDIMKNIEEWA 1326
            VKNHLWVFVN+LIDNPAFDSQTKETLT R +SFGS  + S +FL KVAKS +++N+  WA
Sbjct: 356  VKNHLWVFVNSLIDNPAFDSQTKETLTTRQSSFGSKCELSQEFLKKVAKSGVVENLLSWA 415

Query: 1327 EFKQKKDLKKTDGSKDRRIYGLAKLADANEAGGKNSEKCTLILTEGDSAKALAIAGLSVV 1506
            +FKQ KDLKKTDG+K +RI G+ KL DAN+AGG+NSEKCTLILTEGDSAKALA+AG+SVV
Sbjct: 416  DFKQSKDLKKTDGAKRQRITGITKLEDANDAGGRNSEKCTLILTEGDSAKALAMAGISVV 475

Query: 1507 GRDHYGVFPLRGKLLNVREASHNQLMQNVEIQHIKQILGLQHGKQYDSVKPLRYGHLMIM 1686
            GR++YGVFPLRGKLLNVREA+H Q+M N EIQ+IKQILGLQHGK+YDSVK LRYGHLMIM
Sbjct: 476  GRNNYGVFPLRGKLLNVREATHKQIMDNAEIQNIKQILGLQHGKEYDSVKSLRYGHLMIM 535

Query: 1687 TDQDHDGSHIKGLLINFIHSFWPSLLKVPTFLLEFITPIVKATHRDGKRKESFYTMPQYE 1866
            TDQDHDGSHIKGLLINFIHSFWPSLLK+P+FL+EFITPIVKATH++GK   SFY+MP+YE
Sbjct: 536  TDQDHDGSHIKGLLINFIHSFWPSLLKIPSFLVEFITPIVKATHKNGKVL-SFYSMPEYE 594

Query: 1867 TWKQNQGTDVKNWTIKYYKGLGTSTDQEAKEYFEALGRHKKDFVWVDEQDGDAIELAFSK 2046
            +WK   G +   W+IKYYKGLGTST +E KEYF+ L +HKKDF+WVD++DGDAIELAFSK
Sbjct: 595  SWKX-LGGNASGWSIKYYKGLGTSTSKEGKEYFKDLHKHKKDFLWVDDRDGDAIELAFSK 653

Query: 2047 KKIEARKNWLRQFEPGTYLCDLEEHIKYRDFVHKELILFSIADLQRSIPSMVDGLKPGQR 2226
            KKIEARKNWLRQFEPGT L   E+ IKY DFV+KELILFS+ADLQRSIPSMVDGLKPGQR
Sbjct: 654  KKIEARKNWLRQFEPGTCLDQKEKLIKYSDFVNKELILFSMADLQRSIPSMVDGLKPGQR 713

Query: 2227 KILFCSFKRNFIKEAKVAQFSGYVSEHSAYHHGEQSLASTIIGMAQDYVGSNNINLLLPN 2406
            KILFC+FKRN IKEAKVAQFSGYVSEHSAYHHGEQSL STIIGMAQDYVGSNNINL  PN
Sbjct: 714  KILFCAFKRNLIKEAKVAQFSGYVSEHSAYHHGEQSLMSTIIGMAQDYVGSNNINLFQPN 773

Query: 2407 GQFGTRGQGGKDHASARYIYTQLSSITRFLFPKADDFLLNYLNEDGQSIEPTWYVPTIPM 2586
            GQFGTR QGGKDHASARYIYT+LS ITRFLFPK DD LL+YLNEDGQSIEPTWY+P IP 
Sbjct: 774  GQFGTRHQGGKDHASARYIYTRLSPITRFLFPKGDDILLDYLNEDGQSIEPTWYMPIIPT 833

Query: 2587 VLVNGSEGIGTGWSTFIPNYNPLDIIANVRHLLNDEPMEPMHPWYKGFIGSIEKTATKEA 2766
            VLVNGSEGIGTGWS++IPNYNP DI+AN++ LLN EPMEPM PWYKGF G IEKTATKEA
Sbjct: 834  VLVNGSEGIGTGWSSYIPNYNPRDIVANIKRLLNGEPMEPMDPWYKGFKGLIEKTATKEA 893

Query: 2767 GNSYTVSGIIEEVDETSLRITELPIRKWTQDYKEFLESVSAENDKSKDPFIEGCRDNSGG 2946
            G+SYTVSGIIEE++ET+LRITELPIR+WTQDYKEFLES+   NDK K+PFI+  ++++  
Sbjct: 894  GSSYTVSGIIEEINETTLRITELPIRRWTQDYKEFLESIMTGNDKIKEPFIKDYKEHNDD 953

Query: 2947 EIVHFSVYMSPNNLSEAKQEGLMKKFKLTTSISTSNMHLFDSKGVIKKYDTPEQIIEEFF 3126
              VHF + +S  NL  AKQEGLMKKFKLTT+ISTSNMHLFD KG IKKYD PEQI+EEFF
Sbjct: 954  TTVHFEIILSEENLMMAKQEGLMKKFKLTTTISTSNMHLFDPKGTIKKYDNPEQILEEFF 1013

Query: 3127 HIRLEFYDKRKKALLANLENDMLKCDNKYRFIRGVVDGSIIVSNRKRADLFLELKEKGFT 3306
            H+RLEFY+KRKK  L NLE D+LK DNK RFI GVV G IIVSNRKR DLFLEL++KGFT
Sbjct: 1014 HLRLEFYEKRKKTQLDNLELDLLKLDNKVRFILGVVKGEIIVSNRKRVDLFLELQQKGFT 1073

Query: 3307 PFPKKKTAAEIAIAGSTDDADESEENNDVAIGKGVSASDYDYLLSLAIGTLTAEKMKELR 3486
            PFPKK  A E A+AG+ +D +E+EEN++V   +GV ASDY+YLLS+AIGTLT EK++EL 
Sbjct: 1074 PFPKKTKALEAAVAGANEDGEENEENSEVVSSRGVRASDYEYLLSMAIGTLTLEKVQELC 1133

Query: 3487 DERDKLMQEVEELKRATVKSLWMHDLDALESKFIEELNKSEKKWAENRQ----RILGEA- 3651
             +RDKL  EVEEL++AT  SLWM+DLDALE K ++E +K++ +  E R+    R++ EA 
Sbjct: 1134 SDRDKLNHEVEELRKATPNSLWMNDLDALE-KELDEQDKNDAQAEEARKELKNRVMSEAG 1192

Query: 3652 -KGTRPVQTKPRK-NTKKASNKESVVEQMEVSDNTVTETDKVGEVXXXXXXXXXXXXXXX 3825
             K +R     PRK N KK S  E+V E +  S +  +  + V EV               
Sbjct: 1193 MKASRQAPKNPRKTNAKKPSTSETVTESVAAS-SVGSAMETVPEVVKPKGRGGRPKKAPA 1251

Query: 3826 XXXXXXXXXXXXXXXXXXXLRHRLAAYNFDSSPDRSEDMETEQPQMPTKKKEPNRRTAAQ 4005
                               L+ RLAAYN DSSP++S  METE  ++P KKKEP++R AAQ
Sbjct: 1252 KKDNMRLVDSDEDDVDVIELKERLAAYNLDSSPEQSAVMETEVAKVPAKKKEPSKRAAAQ 1311

Query: 4006 KKPLSTVS----------ETXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXTKPPLA 4155
            K+P S             +T                                       A
Sbjct: 1312 KQPSSYTEISDDDDGMDVQTIREESIGEIVSDEDFEPEVEEAPKGGRGGRKPAANGKAAA 1371

Query: 4156 GTKKRGQQANKQQT---QKLITEVLKPAEN---SPEKKVRKMRASPFNKKSSSILGRTIS 4317
             TKKRG  ANKQ +   QK IT++LKPAEN   SPEKKVRKMRASPFNKKS S+LGR   
Sbjct: 1372 STKKRG-AANKQTSVLGQKKITDLLKPAENAGVSPEKKVRKMRASPFNKKSGSVLGRVGG 1430

Query: 4318 VDXXXXXXXXXXXXNSVSTLGSVTEDVSQAVAPKARPQRGTRGNARY 4458
            +                S+  + + ++S+ V  + RPQR  RG A+Y
Sbjct: 1431 MVGDISPMGSEEQQTGTSSASTDSAELSEVVPARPRPQRVNRGKAKY 1477


>ref|XP_010241213.1| PREDICTED: DNA topoisomerase 2-like isoform X1 [Nelumbo nucifera]
          Length = 1504

 Score = 1932 bits (5006), Expect = 0.0
 Identities = 992/1487 (66%), Positives = 1156/1487 (77%), Gaps = 23/1487 (1%)
 Frame = +1

Query: 67   MAGAKKAPLTTSNNANIPPSETVTAAGGKKTIEQTYQKKTQLEHILLRPDTYIGSIEKHT 246
            MA  +K PL TSN AN+P S  +  +G  KTIE+TYQKK+QLEHILLRPDTY+GSIEKHT
Sbjct: 1    MALERKLPLQTSNIANVPSSRPLVGSG--KTIEETYQKKSQLEHILLRPDTYVGSIEKHT 58

Query: 247  QTLWVYENEQMVQKSITFVPGLYKIFDEILVNAADNKQRDPKMDSVKVTIDVESSCISVY 426
            QTLWVY+  +MV + +T+VPGLYKIFDEILVNAADNKQRDP MDSVKV ID E +CISVY
Sbjct: 59   QTLWVYDGGEMVHRPVTYVPGLYKIFDEILVNAADNKQRDPSMDSVKVVIDAEQNCISVY 118

Query: 427  NNGDGVPVEIHQEEGVYVPELIFGHLLTSSNYDDNEKKTTGGRNGYGAKLTNIFSTEFVI 606
            NNGDGVPVEIHQEEGVYVPELIFGHLLTSSNYDD  KKTTGGRNGYGAKLTNIFSTEF+I
Sbjct: 119  NNGDGVPVEIHQEEGVYVPELIFGHLLTSSNYDDTVKKTTGGRNGYGAKLTNIFSTEFII 178

Query: 607  ETADGKRQRKYKQVFSNNMGTKTEPIISKCKAGENWTRITFKPDLVKFSMSYLEEDVVAL 786
            ETADGKRQ+KYKQVFSNNMG K+EP I+KCK  ENWT++TFKPDL KF++++LE+DVVAL
Sbjct: 179  ETADGKRQKKYKQVFSNNMGKKSEPAITKCKGSENWTKVTFKPDLAKFNLTHLEDDVVAL 238

Query: 787  MKKRVIDVAGCLGKTVKVELNGQLFHFKSFSNYCDLYMKSTSVSTLDPLPRFEEEVHDRW 966
            MKKRVID+AGCLGKTVKVELNGQ    KSF +Y +LY++S S S  +PLPR  E+V +RW
Sbjct: 239  MKKRVIDLAGCLGKTVKVELNGQRVPVKSFLDYVNLYLQSASKSRPEPLPRITEKVSERW 298

Query: 967  QVCISRSEGQFQQVSFVNGIATVKGGTHVDYVTNKITSHLVSVIXXXXXXXXXFDLKPHT 1146
            +VC+S SEGQFQQVSFVNGIAT+KGGTHVDYVTN+IT+H+++++          +LK HT
Sbjct: 299  EVCVSLSEGQFQQVSFVNGIATIKGGTHVDYVTNQITNHVMTIVNKKNKNA---NLKAHT 355

Query: 1147 VKNHLWVFVNALIDNPAFDSQTKETLTLRAASFGSSWDFSSKFLDKVAKSDIMKNIEEWA 1326
            VKNHLWVFVN+LIDNPAFDSQTKETLT R +SFGS  + S +FL KVAKS +++N+  WA
Sbjct: 356  VKNHLWVFVNSLIDNPAFDSQTKETLTTRQSSFGSKCELSQEFLKKVAKSGVVENLLSWA 415

Query: 1327 EFKQKKDLKKTDGSKDRRIYGLAKLADANEAGGKNSEKCTLILTEGDSAKALAIAGLSVV 1506
            +FKQ KDLKKTDG+K +RI G+ KL DAN+AGG+NSEKCTLILTEGDSAKALA+AG+SVV
Sbjct: 416  DFKQSKDLKKTDGAKRQRITGITKLEDANDAGGRNSEKCTLILTEGDSAKALAMAGISVV 475

Query: 1507 GRDHYGVFPLRGKLLNVREASHNQLMQNVEIQHIKQILGLQHGKQYDSVKPLRYGHLMIM 1686
            GR++YGVFPLRGKLLNVREA+H Q+M N EIQ+IKQILGLQHGK+YDSVK LRYGHLMIM
Sbjct: 476  GRNNYGVFPLRGKLLNVREATHKQIMDNAEIQNIKQILGLQHGKEYDSVKSLRYGHLMIM 535

Query: 1687 TDQDHDGSHIKGLLINFIHSFWPSLLKVPTFLLEFITPIVKATHRDGKRKESFYTMPQYE 1866
            TDQDHDGSHIKGLLINFIHSFWPSLLK+P+FL+EFITPIVKATH++GK   SFY+MP+YE
Sbjct: 536  TDQDHDGSHIKGLLINFIHSFWPSLLKIPSFLVEFITPIVKATHKNGKVL-SFYSMPEYE 594

Query: 1867 TWKQNQGTDVKNWTIKYYKGLGTSTDQEAKEYFEALGRHKKDFVWVDEQDGDAIELAFSK 2046
            +WK   G +   W+IKYYKGLGTST +E KEYF+ L +HKKDF+WVD++DGDAIELAFSK
Sbjct: 595  SWKX-LGGNASGWSIKYYKGLGTSTSKEGKEYFKDLHKHKKDFLWVDDRDGDAIELAFSK 653

Query: 2047 KKIEARKNWLRQFEPGTYLCDLEEHIKYRDFVHKELILFSIADLQRSIPSMVDGLKPGQR 2226
            KKIEARKNWLRQFEPGT L   E+ IKY DFV+KELILFS+ADLQRSIPSMVDGLKPGQR
Sbjct: 654  KKIEARKNWLRQFEPGTCLDQKEKLIKYSDFVNKELILFSMADLQRSIPSMVDGLKPGQR 713

Query: 2227 KILFCSFKRNFIKEAKVAQFSGYVSEHSAYHHGEQSLASTIIGMAQDYVGSNNINLLLPN 2406
            KILFC+FKRN IKEAKVAQFSGYVSEHSAYHHGEQSL STIIGMAQDYVGSNNINL  PN
Sbjct: 714  KILFCAFKRNLIKEAKVAQFSGYVSEHSAYHHGEQSLMSTIIGMAQDYVGSNNINLFQPN 773

Query: 2407 GQFGTRGQGGKDHASARYIYTQLSSITRFLFPKADDFLLNYLNEDGQSIEPTWYVPTIPM 2586
            GQFGTR QGGKDHASARYIYT+LS ITRFLFPK DD LL+YLNEDGQSIEPTWY+P IP 
Sbjct: 774  GQFGTRHQGGKDHASARYIYTRLSPITRFLFPKGDDILLDYLNEDGQSIEPTWYMPIIPT 833

Query: 2587 VLVNGSEGIGTGWSTFIPNYNPLDIIANVRHLLNDEPMEPMHPWYKGFIGSIEKTATKEA 2766
            VLVNGSEGIGTGWS++IPNYNP DI+AN++ LLN EPMEPM PWYKGF G IEKTATKEA
Sbjct: 834  VLVNGSEGIGTGWSSYIPNYNPRDIVANIKRLLNGEPMEPMDPWYKGFKGLIEKTATKEA 893

Query: 2767 GNSYTVSGIIEEVDETSLRITELPIRKWTQDYKEFLESVSAENDKSKDPFIEGCRDNSGG 2946
            G+SYTVSGIIEE++ET+LRITELPIR+WTQDYKEFLES+   NDK K+PFI+  ++++  
Sbjct: 894  GSSYTVSGIIEEINETTLRITELPIRRWTQDYKEFLESIMTGNDKIKEPFIKDYKEHNDD 953

Query: 2947 EIVHFSVYMSPNNLSEAKQEGLMKKFKLTTSISTSNMHLFDSKGVIKKYDTPEQIIEEFF 3126
              VHF + +S  NL  AKQEGLMKKFKLTT+ISTSNMHLFD KG IKKYD PEQI+EEFF
Sbjct: 954  TTVHFEIILSEENLMMAKQEGLMKKFKLTTTISTSNMHLFDPKGTIKKYDNPEQILEEFF 1013

Query: 3127 HIRLEFYDKRKKALLANLENDMLKCDNKYRFIRGVVDGSIIVSNRKRADLFLELKEKGFT 3306
            H+RLEFY+KRKK  L NLE D+LK DNK RFI GVV G IIVSNRKR DLFLEL++KGFT
Sbjct: 1014 HLRLEFYEKRKKTQLDNLELDLLKLDNKVRFILGVVKGEIIVSNRKRVDLFLELQQKGFT 1073

Query: 3307 PFPKKKTAAEIAIAGSTDDADESEENNDVAIGKGVSASDYDYLLSLAIGTLTAEKMKELR 3486
            PFPKK  A E A+AG+ +D +E+EEN++V   +GV ASDY+YLLS+AIGTLT EK++EL 
Sbjct: 1074 PFPKKTKALEAAVAGANEDGEENEENSEVVSSRGVRASDYEYLLSMAIGTLTLEKVQELC 1133

Query: 3487 DERDKLMQEVEELKRATVKSLWMHDLDALESKFIEELNKSEKKWAENRQ----RILGEA- 3651
             +RDKL  EVEEL++AT  SLWM+DLDALE K ++E +K++ +  E R+    R++ EA 
Sbjct: 1134 SDRDKLNHEVEELRKATPNSLWMNDLDALE-KELDEQDKNDAQAEEARKELKNRVMSEAG 1192

Query: 3652 -KGTRPVQTKPRK-NTKKASNKESVVEQMEVSDNTVTETDKVGEVXXXXXXXXXXXXXXX 3825
             K +R     PRK N KK S  E+V E +  S            V               
Sbjct: 1193 MKASRQAPKNPRKTNAKKPSTSETVTESVAASSVGSAMETVPEVVKPKGRGGRPKKAPAK 1252

Query: 3826 XXXXXXXXXXXXXXXXXXXLRHRLAAYNFDSSPDRSEDMETEQPQMPTKKKEPNRRTAAQ 4005
                               L+ RLAAYN DSSP++S  METE  ++P KKKEP++R AAQ
Sbjct: 1253 KQDNMRLVDSDEDDVDVIELKERLAAYNLDSSPEQSAVMETEVAKVPAKKKEPSKRAAAQ 1312

Query: 4006 KKPLSTVS----------ETXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXTKPPLA 4155
            K+P S             +T                                       A
Sbjct: 1313 KQPSSYTEISDDDDGMDVQTIREESIGEIVSDEDFEPEVEEAPKGGRGGRKPAANGKAAA 1372

Query: 4156 GTKKRGQQANKQQT---QKLITEVLKPAEN---SPEKKVRKMRASPFNKKSSSILGRTIS 4317
             TKKRG  ANKQ +   QK IT++LKPAEN   SPEKKVRKMRASPFNKKS S+LGR   
Sbjct: 1373 STKKRG-AANKQTSVLGQKKITDLLKPAENAGVSPEKKVRKMRASPFNKKSGSVLGRVGG 1431

Query: 4318 VDXXXXXXXXXXXXNSVSTLGSVTEDVSQAVAPKARPQRGTRGNARY 4458
            +                S+  + + ++S+ V  + RPQR  RG A+Y
Sbjct: 1432 MVGDISPMGSEEQQTGTSSASTDSAELSEVVPARPRPQRVNRGKAKY 1478


>emb|CDP07797.1| unnamed protein product [Coffea canephora]
          Length = 1486

 Score = 1932 bits (5005), Expect = 0.0
 Identities = 1000/1485 (67%), Positives = 1170/1485 (78%), Gaps = 21/1485 (1%)
 Frame = +1

Query: 67   MAGAK--KAPLTTSNNANIPPSETVTAAGGKKTIEQTYQKKTQLEHILLRPDTYIGSIEK 240
            MA +K  K PL +SNNANI     V   G  KTIE+TYQKK+QLEHILLRPDTYIGSIEK
Sbjct: 1    MANSKTAKLPLQSSNNANI-----VLPTG--KTIEETYQKKSQLEHILLRPDTYIGSIEK 53

Query: 241  HTQTLWVYENEQMVQKSITFVPGLYKIFDEILVNAADNKQRDPKMDSVKVTIDVESSCIS 420
            H+QTLWV+EN+ MV + I++VPGLYKIFDEILVNAADNKQRDP+MDSVK+ I+VE + IS
Sbjct: 54   HSQTLWVFENDAMVHRQISYVPGLYKIFDEILVNAADNKQRDPRMDSVKIVINVEENFIS 113

Query: 421  VYNNGDGVPVEIHQEEGVYVPELIFGHLLTSSNYDDNEKKTTGGRNGYGAKLTNIFSTEF 600
            VYNNGDGVPVE+HQEEGVYVPELIFGHLLTSSNYDD  KKTTGGRNGYGAKLTNIFSTEF
Sbjct: 114  VYNNGDGVPVEVHQEEGVYVPELIFGHLLTSSNYDDTVKKTTGGRNGYGAKLTNIFSTEF 173

Query: 601  VIETADGKRQRKYKQVFSNNMGTKTEPIISKCKAGENWTRITFKPDLVKFSMSYLEEDVV 780
            VIE+ADG+RQ+KYKQVFSNNMG K++PIISKCK  ENWT++T+KPDL KF+M++LE+DVV
Sbjct: 174  VIESADGRRQKKYKQVFSNNMGNKSQPIISKCKESENWTKVTYKPDLAKFNMTHLEDDVV 233

Query: 781  ALMKKRVIDVAGCLGKTVKVELNGQLFHFKSFSNYCDLYMKSTSVSTLDPLPRFEEEVHD 960
            ALMKKRV+D+AGCLGKTVKVELNGQ    KSFS+YCDLY++S + +  DPLPR  E+V++
Sbjct: 234  ALMKKRVVDLAGCLGKTVKVELNGQRVPVKSFSDYCDLYLQSAAKTRPDPLPRIVEKVNE 293

Query: 961  RWQVCISRSEGQFQQVSFVNGIATVKGGTHVDYVTNKITSHLVSVIXXXXXXXXXFDLKP 1140
            RW+VC S SEGQFQQVSFVNGIAT+KGGTHVDYVTN+IT+H++ ++          +LK 
Sbjct: 294  RWEVCASLSEGQFQQVSFVNGIATIKGGTHVDYVTNQITNHIIGIVNKKNKNA---NLKA 350

Query: 1141 HTVKNHLWVFVNALIDNPAFDSQTKETLTLRAASFGSSWDFSSKFLDKVAKSDIMKNIEE 1320
            H+VKNHLWVFVNALIDNPAFDSQTKETLTLR +SFGS  + S +FL KVAKS +++N+  
Sbjct: 351  HSVKNHLWVFVNALIDNPAFDSQTKETLTLRQSSFGSKCELSQEFLKKVAKSGVVENLLS 410

Query: 1321 WAEFKQKKDLKKTDGSKDRRIYGLAKLADANEAGGKNSEKCTLILTEGDSAKALAIAGLS 1500
            WA+FKQ KDLKKTDG+K +RI G+ KL DAN+AGGKNS++CTLILTEGDSAKALA+AG+S
Sbjct: 411  WADFKQSKDLKKTDGTKRQRITGITKLEDANDAGGKNSDRCTLILTEGDSAKALAMAGIS 470

Query: 1501 VVGRDHYGVFPLRGKLLNVREASHNQLMQNVEIQHIKQILGLQHGKQYDSVKPLRYGHLM 1680
            VVGR+ YGVFPLRGKLLNVREASH Q+M N EIQ+IKQILGLQHGK YDSVK LRYGHLM
Sbjct: 471  VVGRNFYGVFPLRGKLLNVREASHKQIMDNAEIQYIKQILGLQHGKVYDSVKSLRYGHLM 530

Query: 1681 IMTDQDHDGSHIKGLLINFIHSFWPSLLKVPTFLLEFITPIVKATHRDGKRKESFYTMPQ 1860
            IMTDQDHDGSHIKGLLINFIHSFWPSLLK+P+FL+EFITPIVKATH++G R  SFYTMP+
Sbjct: 531  IMTDQDHDGSHIKGLLINFIHSFWPSLLKIPSFLVEFITPIVKATHKNG-RVLSFYTMPE 589

Query: 1861 YETWKQNQGTDVKNWTIKYYKGLGTSTDQEAKEYFEALGRHKKDFVWVDEQDGDAIELAF 2040
            YE+WK++   +   W+IKYYKGLGTST +E KEYF+ LG+HKKDF+WVD+ DG+AIELAF
Sbjct: 590  YESWKESLSGNATGWSIKYYKGLGTSTSKEGKEYFKDLGKHKKDFIWVDDNDGEAIELAF 649

Query: 2041 SKKKIEARKNWLRQFEPGTYLCDLEEHIKYRDFVHKELILFSIADLQRSIPSMVDGLKPG 2220
            SKKKIEARKNWLRQFEPGTYL   E+ IKY DF++KELILFS+ADLQRSIPSMVDGLKPG
Sbjct: 650  SKKKIEARKNWLRQFEPGTYLDQKEKLIKYSDFINKELILFSLADLQRSIPSMVDGLKPG 709

Query: 2221 QRKILFCSFKRNFIKEAKVAQFSGYVSEHSAYHHGEQSLASTIIGMAQDYVGSNNINLLL 2400
            QRKILFCSFKRNF+KEAKVAQFSGYVSEHSAYHHGEQSLAS IIGMAQD+VGSNNINLL 
Sbjct: 710  QRKILFCSFKRNFVKEAKVAQFSGYVSEHSAYHHGEQSLASAIIGMAQDFVGSNNINLLQ 769

Query: 2401 PNGQFGTRGQGGKDHASARYIYTQLSSITRFLFPKADDFLLNYLNEDGQSIEPTWYVPTI 2580
            PNGQFGTR QGGKDHASARY+YT+LS ITR LFPK DD LL+YLNEDGQSIEPTWY+P I
Sbjct: 770  PNGQFGTRNQGGKDHASARYVYTRLSPITRSLFPKDDDILLDYLNEDGQSIEPTWYMPII 829

Query: 2581 PMVLVNGSEGIGTGWSTFIPNYNPLDIIANVRHLLNDEPMEPMHPWYKGFIGSIEKTATK 2760
            PMVLVNGSEGIGTGWS++IPNYNP DII N+R LLN+EPMEPM PWYKGF G+IEKTATK
Sbjct: 830  PMVLVNGSEGIGTGWSSYIPNYNPRDIIGNIRRLLNNEPMEPMEPWYKGFRGTIEKTATK 889

Query: 2761 EAGNSYTVSGIIEEVDETSLRITELPIRKWTQDYKEFLESVSAENDKSKDPFIEGCRDNS 2940
            EAG SYTVSGI+EEVDET++R+TELP+RKWTQDYKEFLES+   N+K KDPFI+  RD++
Sbjct: 890  EAGASYTVSGIVEEVDETTIRVTELPVRKWTQDYKEFLESIMMGNEKVKDPFIKEFRDHT 949

Query: 2941 GGEIVHFSVYMSPNNLSEAKQEGLMKKFKLTTSISTSNMHLFDSKGVIKKYDTPEQIIEE 3120
                V+  + MS  NL  AKQEGL+KKFKLTT+ISTSNMHLFDS+G+IKK+D PEQI+EE
Sbjct: 950  DDTTVYLDIIMSEENLLMAKQEGLLKKFKLTTTISTSNMHLFDSQGIIKKFDNPEQILEE 1009

Query: 3121 FFHIRLEFYDKRKKALLANLENDMLKCDNKYRFIRGVVDGSIIVSNRKRADLFLELKEKG 3300
            FFH+RLEFY+KRKK LL NL+ ++LK DNK RFI  VV+GSIIVSNRKRADLFLELKEKG
Sbjct: 1010 FFHLRLEFYEKRKKVLLDNLQLELLKLDNKVRFILAVVEGSIIVSNRKRADLFLELKEKG 1069

Query: 3301 FTPFPKKKTAAEIAIAGSTDDADESEENNDVAIGKGVSASDYDYLLSLAIGTLTAEKMKE 3480
            FTPFPKKK + E A+AGS +DA+E+EE+++VA  KGV ASDY+YL+S+AIG+LT EK++E
Sbjct: 1070 FTPFPKKK-SVEAAVAGSIEDAEETEESSEVATSKGVRASDYEYLISMAIGSLTLEKVQE 1128

Query: 3481 LRDERDKLMQEVEELKRATVKSLWMHDLDALESKFIEELNKSEKKWAENRQRILGEA--- 3651
            L  +RDKL  EV++L +AT KSLW  DLDALES+ ++E + S+ +    R+ +  +A   
Sbjct: 1129 LCADRDKLKGEVDDLIKATPKSLWTKDLDALESQ-LDEQDISDAQAEAARKEMRSKAMKD 1187

Query: 3652 ---KGTRPVQTKPRKNTKKASNKESVVEQMEVSDNTVTETDKVGEV--XXXXXXXXXXXX 3816
               K TR     PRK  KKASN E   E ME+S ++  ET+ V EV              
Sbjct: 1188 DGPKPTRQAPKNPRKYNKKASNTEPTTEPMEISSSSALETNNVVEVAKPKGKAGPKKAPA 1247

Query: 3817 XXXXXXXXXXXXXXXXXXXXXXLRHRLAAYNF-DSSPDRSEDMETEQPQMPTKKKEPNRR 3993
                                  L+ RLAAYN   SSPD+SE METE P     K+EP++R
Sbjct: 1248 RKGKTFSVLRDEDDEDDDEVLALKDRLAAYNLGSSSPDQSETMETEIP-----KREPSKR 1302

Query: 3994 TAAQKKPLSTVSETXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXTK--PPLAGTKK 4167
             A  KKPL +V+E                                   +K   P A  KK
Sbjct: 1303 -ATTKKPLVSVTEISDDDDDQIEISDDEDFELEVEAAPKEKGRKKTANSKAAKPTAAPKK 1361

Query: 4168 RGQQANKQQT---QKLITEVLKPAE---NSPEKKVRKMRASPFNKKSSSILGRTISVDXX 4329
            RG QANK      QKLITEVLKPA+    SPEKKVR+MR SPFNKKS S+L R    +  
Sbjct: 1362 RG-QANKTSQLVGQKLITEVLKPADVSKISPEKKVRRMRPSPFNKKSGSVLERLSQQETD 1420

Query: 4330 XXXXXXXXXXNS-VSTLGSVTEDVSQAVAPKARPQR-GTRGNARY 4458
                       S  S     TE+ +Q V P+ARP+R G RG A+Y
Sbjct: 1421 KISPESEEQEESPASNASGSTEESAQVVVPRARPRRGGNRGKAKY 1465


>ref|XP_022896608.1| DNA topoisomerase 2 [Olea europaea var. sylvestris]
          Length = 1459

 Score = 1928 bits (4995), Expect = 0.0
 Identities = 988/1464 (67%), Positives = 1143/1464 (78%), Gaps = 4/1464 (0%)
 Frame = +1

Query: 79   KKAPLTTSNNANIPPSETVTAAGGKKTIEQTYQKKTQLEHILLRPDTYIGSIEKHTQTLW 258
            KKAPLTTSNNANI P  T  A    KTIEQTYQKKTQLEHILLRPDTYIGSIEKH+QTLW
Sbjct: 4    KKAPLTTSNNANIVPPNTTGAGVAGKTIEQTYQKKTQLEHILLRPDTYIGSIEKHSQTLW 63

Query: 259  VYENEQMVQKSITFVPGLYKIFDEILVNAADNKQRDPKMDSVKVTIDVESSCISVYNNGD 438
            VYE+ QMVQK I++VPGLYKIFDEILVNAADNKQRDPKM+S+KV+ID E++CISVYNNGD
Sbjct: 64   VYEDNQMVQKPISYVPGLYKIFDEILVNAADNKQRDPKMNSLKVSIDAEANCISVYNNGD 123

Query: 439  GVPVEIHQEEGVYVPELIFGHLLTSSNYDDNEKKTTGGRNGYGAKLTNIFSTEFVIETAD 618
            GVPVEIHQEEGVYVPELIFGHLLTSSNYDD EKKTTGGRNGYGAKLTNIFSTEF+IETAD
Sbjct: 124  GVPVEIHQEEGVYVPELIFGHLLTSSNYDDQEKKTTGGRNGYGAKLTNIFSTEFIIETAD 183

Query: 619  GKRQRKYKQVFSNNMGTKTEPIISKCKAGENWTRITFKPDLVKFSMSYLEEDVVALMKKR 798
            G+RQRKYKQVFS NMG K++P+ISKCK GENWT++TFKPDL KF+M++LE+DV+ALMKKR
Sbjct: 184  GRRQRKYKQVFSCNMGNKSQPLISKCKEGENWTKVTFKPDLAKFNMTHLEDDVLALMKKR 243

Query: 799  VIDVAGCLGKTVKVELNGQLFHFKSFSNYCDLYMKSTSVSTLDPLPRFEEEVHDRWQVCI 978
            VID+AGCLGKTVKVELNG+    KSF  YC+LY+KS          R EE+V DRW+VC+
Sbjct: 244  VIDMAGCLGKTVKVELNGEDIRVKSFGEYCNLYLKSAF--------RMEEKV-DRWEVCV 294

Query: 979  SRSEGQFQQVSFVNGIATVKGGTHVDYVTNKITSHLVSVIXXXXXXXXXFDLKPHTVKNH 1158
            S SEGQFQQVSFVN I+T+KGGTHVDYVTN+I +HL   +          +LK H+VKNH
Sbjct: 295  SLSEGQFQQVSFVNSISTIKGGTHVDYVTNQIANHLAEYVNKKKKNA---NLKAHSVKNH 351

Query: 1159 LWVFVNALIDNPAFDSQTKETLTLRAASFGSSWDFSSKFLDKVAKSDIMKNIEEWAEFKQ 1338
            LWVFVN LIDNPAFDSQTKETLTLR  SFGS    S KFL KVA S+I+ NI EWA+FK+
Sbjct: 352  LWVFVNCLIDNPAFDSQTKETLTLRQKSFGSECRLSDKFLSKVANSEIVNNIMEWADFKE 411

Query: 1339 KKDLKKTDGSKDRRIYGLAKLADANEAGGKNSEKCTLILTEGDSAKALAIAGLSVVGRDH 1518
            KKDLKKTDG+K +RI GL KLADAN AGGKNSEKCTLILTEGDSA  LAIAGLS+VGRDH
Sbjct: 412  KKDLKKTDGTKSKRITGLTKLADANAAGGKNSEKCTLILTEGDSAATLAIAGLSIVGRDH 471

Query: 1519 YGVFPLRGKLLNVREASHNQLMQNVEIQHIKQILGLQHGKQYDSVKPLRYGHLMIMTDQD 1698
            YGVFPLRGKLLNVR+AS  Q+ +N EIQ+IK+ILGLQHGKQYDS+K LRYGH+MIMTDQD
Sbjct: 472  YGVFPLRGKLLNVRDASTKQINENAEIQNIKKILGLQHGKQYDSIKSLRYGHMMIMTDQD 531

Query: 1699 HDGSHIKGLLINFIHSFWPSLLKVPTFLLEFITPIVKATHRDGKRKESFYTMPQYETWKQ 1878
            HDGSHIKGLLINFIHSFWPSLLK+P+FL+EFITPIVKATH++G+ K +FYTMP+YE+WK+
Sbjct: 532  HDGSHIKGLLINFIHSFWPSLLKIPSFLVEFITPIVKATHKNGE-KRAFYTMPEYESWKE 590

Query: 1879 NQGTDVKNWTIKYYKGLGTSTDQEAKEYFEALGRHKKDFVWVDEQDGDAIELAFSKKKIE 2058
            + G   KNW+IKYYKGLGTSTD+E KEYF+ L +HKKDFVW D+ DG+AIELAFSKKKIE
Sbjct: 591  SLGDRAKNWSIKYYKGLGTSTDKEGKEYFKDLEKHKKDFVWGDDHDGEAIELAFSKKKIE 650

Query: 2059 ARKNWLRQFEPGTYLCDLEEHIKYRDFVHKELILFSIADLQRSIPSMVDGLKPGQRKILF 2238
            ARKNWLRQFEPGTYL   E+ IKYRDFV+KELILFS+ADLQRSIPSMVDGLKPGQRKILF
Sbjct: 651  ARKNWLRQFEPGTYLDQEEKLIKYRDFVNKELILFSMADLQRSIPSMVDGLKPGQRKILF 710

Query: 2239 CSFKRNFIKEAKVAQFSGYVSEHSAYHHGEQSLASTIIGMAQDYVGSNNINLLLPNGQFG 2418
            C+FKRNF+ EAKV QFSGYVSEHSAYHHGEQSLASTIIGMAQ YVGSNNIN+L PNGQFG
Sbjct: 711  CAFKRNFVHEAKVGQFSGYVSEHSAYHHGEQSLASTIIGMAQKYVGSNNINILKPNGQFG 770

Query: 2419 TRGQGGKDHASARYIYTQLSSITRFLFPKADDFLLNYLNEDGQSIEPTWYVPTIPMVLVN 2598
            TR QGGKDHASARYI+TQLS+ITRFLFPK DD +L+Y NEDGQ+IEPTWYVP IPMVLVN
Sbjct: 771  TRNQGGKDHASARYIFTQLSAITRFLFPKDDDIILDYQNEDGQTIEPTWYVPIIPMVLVN 830

Query: 2599 GSEGIGTGWSTFIPNYNPLDIIANVRHLLNDEPMEPMHPWYKGFIGSIEKTATKEAGNSY 2778
            GSEGIGTGWS+F+PNYNP DIIANVRH+LNDEPMEPM PWYKGF G+IEKTATKEAG +Y
Sbjct: 831  GSEGIGTGWSSFVPNYNPRDIIANVRHMLNDEPMEPMDPWYKGFSGTIEKTATKEAGATY 890

Query: 2779 TVSGIIEEVDETSLRITELPIRKWTQDYKEFLESVSAENDKSKDPFIEGCRDNSGGEIVH 2958
            T +GIIEEV +T+LRITELPIR+WTQDYK++LES+         PFIE  R+    + V+
Sbjct: 891  TATGIIEEVSDTTLRITELPIRRWTQDYKDYLESLY--------PFIEEVREYHTTDSVN 942

Query: 2959 FSVYMSPNNLSEAKQEGLMKKFKLTTSISTSNMHLFDSKGVIKKYDTPEQIIEEFFHIRL 3138
            F + +S  N+  AKQEGL+KKFKLTT+ISTSNMHLFDSKGVIKKYDTPE+I+E+F+ IR 
Sbjct: 943  FEIDLSEENMMIAKQEGLLKKFKLTTTISTSNMHLFDSKGVIKKYDTPEKILEDFYSIRF 1002

Query: 3139 EFYDKRKKALLANLENDMLKCDNKYRFIRGVVDGSIIVSNRKRADLFLELKEKGFTPFPK 3318
            EFY+KRKK L+ NLE ++L  +NK RFI  VV+G IIVSNR+RADL LELK+KGFTPFPK
Sbjct: 1003 EFYEKRKKVLMDNLERELLILENKVRFILNVVEGKIIVSNRRRADLVLELKDKGFTPFPK 1062

Query: 3319 KKTAAEIAIAGSTDDADESEENNDVAIGKGVSASDYDYLLSLAIGTLTAEKMKELRDERD 3498
            K    E+++AGS+D  +E+EEN+D+A  +GV ASDYDYLLS++IG+LT EK++EL + RD
Sbjct: 1063 KTKTVEVSVAGSSDVPEETEENSDMANSQGVRASDYDYLLSMSIGSLTIEKVQELCNNRD 1122

Query: 3499 KLMQEVEELKRATVKSLWMHDLDALESKFIEELNKSEKKWAENRQRILGE--AKGTRPVQ 3672
            KL+QEVEE+++AT+KSLW+ DLDALE++ ++E +K +    E+   I  +   K  +P  
Sbjct: 1123 KLIQEVEEMRQATIKSLWIKDLDALETE-LDEQDKRDALAEEDELEIKPKRGRKAPKPAM 1181

Query: 3673 TKPRKNTKKASNKESVVEQMEVSDNTVTETDKVGEVXXXXXXXXXXXXXXXXXXXXXXXX 3852
              PRKN KK    ESVVE ME+S N+  E D                             
Sbjct: 1182 KNPRKNNKKVGKTESVVEPMEISTNSEIEKDNA--------RVAVQKKAPRKGKSVAALK 1233

Query: 3853 XXXXXXXXXXLRHRLAAYNFDSSPDRSEDMETEQPQMPTKKKEPNRRTAAQKKPLSTVSE 4032
                      L  R+AAYN DSSPD  E  E E  ++  KKK P +R AA KKPLSTV+E
Sbjct: 1234 DEEDDDEILALNERIAAYNLDSSPDHEEVAEAEVSEVQIKKKGPTKRAAATKKPLSTVTE 1293

Query: 4033 TXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXTKPPLAGTKKRGQQANKQQT--QKL 4206
                                                KPP     KRG  A + Q   QKL
Sbjct: 1294 --ISDDEDDQDFDLEGGMPAEEKKKAGRKPAAAKTAKPPPG--MKRGPAAKQSQLMGQKL 1349

Query: 4207 ITEVLKPAENSPEKKVRKMRASPFNKKSSSILGRTISVDXXXXXXXXXXXXNSVSTLGSV 4386
            ITEVL+ A +SPEKKVRKMR SPFNKKS S+LGR  ++                S   + 
Sbjct: 1350 ITEVLQGAVDSPEKKVRKMRISPFNKKSGSVLGRMATM------------GEDESPTSAG 1397

Query: 4387 TEDVSQAVAPKARPQRGTRGNARY 4458
            TED +Q V P+ARPQR     A Y
Sbjct: 1398 TEDSTQVVVPRARPQRANSRKATY 1421


>ref|XP_002274267.1| PREDICTED: DNA topoisomerase 2 [Vitis vinifera]
          Length = 1489

 Score = 1922 bits (4979), Expect = 0.0
 Identities = 984/1482 (66%), Positives = 1159/1482 (78%), Gaps = 18/1482 (1%)
 Frame = +1

Query: 67   MAGAKKAPLTTSNNANIPPSETVTAAGGKKTIEQTYQKKTQLEHILLRPDTYIGSIEKHT 246
            MA   K PL +SNNAN+P      A    KTIE+TYQKK+QLEHILLRPDTYIGSIEKHT
Sbjct: 1    MAVDNKLPLQSSNNANMP------AKPAGKTIEETYQKKSQLEHILLRPDTYIGSIEKHT 54

Query: 247  QTLWVYENEQMVQKSITFVPGLYKIFDEILVNAADNKQRDPKMDSVKVTIDVESSCISVY 426
            Q LWV+EN +MV +S+++VPGLYKIFDEILVNAADNKQRDP MDSVKV IDVE +CISVY
Sbjct: 55   QALWVFENNEMVHRSVSYVPGLYKIFDEILVNAADNKQRDPSMDSVKVVIDVEKNCISVY 114

Query: 427  NNGDGVPVEIHQEEGVYVPELIFGHLLTSSNYDDNEKKTTGGRNGYGAKLTNIFSTEFVI 606
            NNGDGVPVEIHQEEGVYVPE+IFGHLLTSSNYDD+ KKTTGGRNGYGAKLTNIFSTEFVI
Sbjct: 115  NNGDGVPVEIHQEEGVYVPEMIFGHLLTSSNYDDDVKKTTGGRNGYGAKLTNIFSTEFVI 174

Query: 607  ETADGKRQRKYKQVFSNNMGTKTEPIISKCKAGENWTRITFKPDLVKFSMSYLEEDVVAL 786
            ETADG+RQ+KYKQVFSNNMG K+EP+I+KCK  ENWT+++FKPDL KF+M++LE+DVVAL
Sbjct: 175  ETADGRRQKKYKQVFSNNMGKKSEPVITKCKERENWTKVSFKPDLAKFNMTHLEDDVVAL 234

Query: 787  MKKRVIDVAGCLGKTVKVELNGQLFHFKSFSNYCDLYMKSTSVSTLDPLPRFEEEVHDRW 966
            MKKRV+D+AGCLGKTVKVELNGQ    KSF++Y +LY++S + S  + LPR  E+V++RW
Sbjct: 235  MKKRVVDIAGCLGKTVKVELNGQRIPVKSFNDYVNLYLQSAAKSRPESLPRIAEKVNERW 294

Query: 967  QVCISRSEGQFQQVSFVNGIATVKGGTHVDYVTNKITSHLVSVIXXXXXXXXXFDLKPHT 1146
            ++C+S SEGQFQQVSFVN IAT+KGGTHVDYVTN+I + ++S++          ++K HT
Sbjct: 295  EICVSLSEGQFQQVSFVNSIATIKGGTHVDYVTNQIANFVMSIVNKKNKNA---NIKAHT 351

Query: 1147 VKNHLWVFVNALIDNPAFDSQTKETLTLRAASFGSSWDFSSKFLDKVAKSDIMKNIEEWA 1326
            VKNHLWVFVNALIDNPAFDSQTKETLT+R +SFGS  + S +FL KV+KS +++++  WA
Sbjct: 352  VKNHLWVFVNALIDNPAFDSQTKETLTIRQSSFGSKCELSQEFLKKVSKSGVVESLLSWA 411

Query: 1327 EFKQKKDLKKTDGSKDRRIYGLAKLADANEAGGKNSEKCTLILTEGDSAKALAIAGLSVV 1506
            ++KQ KDLKKTDG+K +R+ G+ KL DAN+AGG+NSEKCTLILTEGDSAKALA+AG+SVV
Sbjct: 412  DYKQNKDLKKTDGTKRQRLTGITKLEDANDAGGRNSEKCTLILTEGDSAKALAMAGISVV 471

Query: 1507 GRDHYGVFPLRGKLLNVREASHNQLMQNVEIQHIKQILGLQHGKQYDSVKPLRYGHLMIM 1686
            GR+HYGVFPLRGKLLNVR+A   Q+++N EIQ+IKQILGLQ GK+YDS+K LRYGHLMIM
Sbjct: 472  GRNHYGVFPLRGKLLNVRDAQKKQILENAEIQNIKQILGLQQGKEYDSIKSLRYGHLMIM 531

Query: 1687 TDQDHDGSHIKGLLINFIHSFWPSLLKVPTFLLEFITPIVKATHRDGKRKESFYTMPQYE 1866
            TDQDHDGSHIKGLLINFIHSFWPSLLK+P+FL+EFITPIVKATHR+G R  SFY+MP+YE
Sbjct: 532  TDQDHDGSHIKGLLINFIHSFWPSLLKIPSFLVEFITPIVKATHRNG-RVLSFYSMPEYE 590

Query: 1867 TWKQNQGTDVKNWTIKYYKGLGTSTDQEAKEYFEALGRHKKDFVWVDEQDGDAIELAFSK 2046
            +WK++ G +   W+IKYYKGLGTST +E KEYF+ LG+HKKDF+WVDE+DGDAIELAFSK
Sbjct: 591  SWKESLGGNASGWSIKYYKGLGTSTSKEGKEYFKDLGKHKKDFMWVDEKDGDAIELAFSK 650

Query: 2047 KKIEARKNWLRQFEPGTYLCDLEEHIKYRDFVHKELILFSIADLQRSIPSMVDGLKPGQR 2226
            KKIE RKNWLRQF+PGTYL   E+ IKY DFV+KELILFS+ADLQRSIPSMVDGLKPGQR
Sbjct: 651  KKIEERKNWLRQFQPGTYLDQKEKLIKYSDFVNKELILFSMADLQRSIPSMVDGLKPGQR 710

Query: 2227 KILFCSFKRNFIKEAKVAQFSGYVSEHSAYHHGEQSLASTIIGMAQDYVGSNNINLLLPN 2406
            KILFCSFKRNFIKEAK+AQFSGYVSEHSAYHHGEQSLASTIIGMAQD+VGSNNINLLLPN
Sbjct: 711  KILFCSFKRNFIKEAKIAQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPN 770

Query: 2407 GQFGTRGQGGKDHASARYIYTQLSSITRFLFPKADDFLLNYLNEDGQSIEPTWYVPTIPM 2586
            GQFGTR QGGKDHASARYIYT+LS ITRFLFPK DD LL+YLNEDGQSIEPTWYVPTIPM
Sbjct: 771  GQFGTRHQGGKDHASARYIYTRLSPITRFLFPKDDDILLDYLNEDGQSIEPTWYVPTIPM 830

Query: 2587 VLVNGSEGIGTGWSTFIPNYNPLDIIANVRHLLNDEPMEPMHPWYKGFIGSIEKT-ATKE 2763
            VLVNGSEGIGTGWS+ IPNYNP DIIANVR LLN E MEPM PWY+GF G+IEKT  TK+
Sbjct: 831  VLVNGSEGIGTGWSSSIPNYNPRDIIANVRRLLNGEMMEPMDPWYRGFRGTIEKTDPTKQ 890

Query: 2764 AGNSYTVSGIIEEVDETSLRITELPIRKWTQDYKEFLESVSAENDKSKDPFIEGCRDNSG 2943
                YTV GIIEEV+ET+LRI+ELP+RKWTQDYKEFLES+   NDK KDPFI+  ++++ 
Sbjct: 891  ESVGYTVKGIIEEVNETTLRISELPVRKWTQDYKEFLESIMTGNDKIKDPFIKDYKEHND 950

Query: 2944 GEIVHFSVYMSPNNLSEAKQEGLMKKFKLTTSISTSNMHLFDSKGVIKKYDTPEQIIEEF 3123
               VHF V MS  NL  AKQEGL++KFKLTT ISTSNMHLFDS G IKKY+TPEQI+EEF
Sbjct: 951  DTTVHFEVIMSEENLLMAKQEGLLQKFKLTTKISTSNMHLFDSNGTIKKYETPEQILEEF 1010

Query: 3124 FHIRLEFYDKRKKALLANLENDMLKCDNKYRFIRGVVDGSIIVSNRKRADLFLELKEKGF 3303
            FH+RLEFY+KRK+ LL NLE ++LK +NK RFI GVV G IIVSNRKRADLF EL +KGF
Sbjct: 1011 FHLRLEFYEKRKRVLLDNLELELLKLENKVRFILGVVRGEIIVSNRKRADLFHELHQKGF 1070

Query: 3304 TPFPKKKTAAEIAIAGSTDDADESEENNDVAIGKGVSASDYDYLLSLAIGTLTAEKMKEL 3483
            TPFPKK  + EIA+AG+TDD +E+EEN D     GV A+DY+YLLS+AIGTLT EK++EL
Sbjct: 1071 TPFPKKSKSVEIAVAGATDDTEEAEENTDAVSKGGVRATDYEYLLSMAIGTLTLEKVQEL 1130

Query: 3484 RDERDKLMQEVEELKRATVKSLWMHDLDALESKFIEELNKSEKKWAENRQ----RILGEA 3651
              +RDKL + V++LK+AT K+LW+ DLDALE + ++E +K++ +  E R+    R++ EA
Sbjct: 1131 CADRDKLNKGVDDLKKATPKALWITDLDALERE-LDEQDKNDARAEETRKQLKSRVMSEA 1189

Query: 3652 --KGTRPVQTKPRKNTKKASNKESVVEQMEVSDNTVTETDKVGEVXXXXXXXXXXXXXXX 3825
              K +R     PRKN KKA+N E   E M+VS ++  E + V EV               
Sbjct: 1190 GMKVSRQAPKNPRKNNKKANNAEPAAETMDVSASSAMEMESVPEVVKPKGRAAPRKAPAK 1249

Query: 3826 XXXXXXXXXXXXXXXXXXXLRHRLAAYNFDSSPDRSEDMETEQPQMP-TKKKEPNRRTAA 4002
                               L+ RLAAYN +SSPD S  ME E PQ+P  +KKEP+RR AA
Sbjct: 1250 KKEMPTSVLKDEDDDEVHELKERLAAYNLESSPDGSAAMEAEVPQVPAARKKEPSRRAAA 1309

Query: 4003 QKKPLSTVSE--TXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXTKPPLAGTKKRGQ 4176
            QKKPL++ +E                                      KP  A  K +  
Sbjct: 1310 QKKPLASFTEISDDDEDDEDFEVEEVSASDVKKKGGRKPAANAKAAAAKPAAAAAKNKRG 1369

Query: 4177 QANKQQT----QKLITEVLKPAEN---SPEKKVRKMRASPFNKKSSSILGRTISVDXXXX 4335
             ANKQQ     Q L+TE+ KPAE    SPEKKVRKMRASPFNKKS S+LG T   D    
Sbjct: 1370 AANKQQPQLLGQTLLTEIFKPAETLGISPEKKVRKMRASPFNKKSGSVLGSTGEED---E 1426

Query: 4336 XXXXXXXXNSVSTLGSVTEDVSQAVAP-KARPQRGTRGNARY 4458
                     S ST  S   + ++ V P + RPQR  R   RY
Sbjct: 1427 TAETEENSGSASTSNSSGGESNEVVMPARTRPQRENRVQTRY 1468


>gb|OVA19386.1| DNA topoisomerase II [Macleaya cordata]
          Length = 1515

 Score = 1903 bits (4929), Expect = 0.0
 Identities = 986/1518 (64%), Positives = 1153/1518 (75%), Gaps = 54/1518 (3%)
 Frame = +1

Query: 67   MAGAKKAPLTTSNNANIPPSETVTAAGGKKTIEQTYQKKTQLEHILLRPDTYIGSIEKHT 246
            M   KK PL TSNN N+  S T    G  KTIE+TYQKKTQLEHILLRPDTY+GSIEKHT
Sbjct: 1    MTVEKKLPLQTSNNVNVAGSRTQNPPG--KTIEETYQKKTQLEHILLRPDTYVGSIEKHT 58

Query: 247  QTLWVYENEQMVQKSITFVPGLYKIFDEILVNAADNKQRDPKMDSVKVTIDVESSCISVY 426
            Q LWVYE  +MV + +++VPGLYKIFDEILVNAADNKQRDP MDSVKV IDVE +CISVY
Sbjct: 59   QNLWVYEGGEMVYRPVSYVPGLYKIFDEILVNAADNKQRDPSMDSVKVDIDVEQNCISVY 118

Query: 427  NNGDGVPVEIHQEEGVYVPELIFGHLLTSSNYDDNEKKTTGGRNGYGAKLTNIFSTEFVI 606
            NNGDGVPVEIHQEEGVYVPELIFGHLLTSSNYDD  KKTTGGRNGYGAKLTNIFSTEFVI
Sbjct: 119  NNGDGVPVEIHQEEGVYVPELIFGHLLTSSNYDDTVKKTTGGRNGYGAKLTNIFSTEFVI 178

Query: 607  ETADGKRQRKYKQVFSNNMGTKTEPIISKCKAGENWTRITFKPDLVKFSMSYLEEDVVAL 786
            +TADGKRQ+KYKQVF+NNMGTK+EP I+KCK  ENWT+++FKPDL KF+M++LE+DVVAL
Sbjct: 179  QTADGKRQKKYKQVFTNNMGTKSEPNITKCKESENWTKVSFKPDLAKFNMTHLEDDVVAL 238

Query: 787  MKKRVIDVAGCLGKTVKVELNGQLFHFKSFSNYCDLYMKSTSVSTLDPLPRF-------- 942
            MKKRVID+AGCLGKTVKVELNGQ    KSF +Y +LY++S S +  D LPRF        
Sbjct: 239  MKKRVIDMAGCLGKTVKVELNGQRVPVKSFLDYVNLYVQSASKNRPDSLPRFVSDKFEST 298

Query: 943  -------------------EEEVHDRWQVCISRSEGQFQQVSFVNGIATVKGGTHVDYVT 1065
                                E+V+DRW++C+S SEGQFQQVSFVNGIAT+KGGTHVDYVT
Sbjct: 299  HSNLFPFRILKQFDFSNRITEKVNDRWEICVSLSEGQFQQVSFVNGIATIKGGTHVDYVT 358

Query: 1066 NKITSHLVSVIXXXXXXXXXFDLKPHTVKNHLWVFVNALIDNPAFDSQTKETLTLRAASF 1245
            N+IT+H+++++          +LK HTVKNHLWVFVNALIDNPAFDSQTKETLT R  SF
Sbjct: 359  NQITNHVMTIVNKKNKNA---NLKAHTVKNHLWVFVNALIDNPAFDSQTKETLTTRQGSF 415

Query: 1246 GSSWDFSSKFLDKVAKSDIMKNIEEWAEFKQKKDLKKTDGSKDRRIYGLAKLADANEAGG 1425
            G+  + S +FL KVAKS +++++  WA+FKQ KDLKKTDG+K +RI G+ KL DAN+AGG
Sbjct: 416  GTKCELSQEFLKKVAKSGVVESLLSWADFKQSKDLKKTDGAKRQRITGITKLEDANDAGG 475

Query: 1426 KNSEKCTLILTEGDSAKALAIAGLSVVGRDHYGVFPLRGKLLNVREASHNQLMQNVEIQH 1605
            +NS+KCTLILTEGDSAKALA+AG+SVVGR++YGVFPLRGKLLNVREASH Q+M+N EIQ 
Sbjct: 476  RNSDKCTLILTEGDSAKALAMAGISVVGRNYYGVFPLRGKLLNVREASHKQIMENAEIQS 535

Query: 1606 IKQILGLQHGKQYDSVKPLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKVPTFLL 1785
            IKQILGLQHGK+YDSVK LRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLK+P+FL+
Sbjct: 536  IKQILGLQHGKEYDSVKSLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKIPSFLI 595

Query: 1786 EFITPIVKATHRDGKRKESFYTMPQYETWKQNQGTDVKNWTIKYYKGLGTSTDQEAKEYF 1965
            EFITPIVKATH++GK   SFY+MP+YE WK++ G +   W+IKYYKGLGTST +E KEYF
Sbjct: 596  EFITPIVKATHKNGKVM-SFYSMPEYEQWKESLGGNASGWSIKYYKGLGTSTSKEGKEYF 654

Query: 1966 EALGRHKKDFVWVDEQDGDAIELAFSKKKIEARKNWLRQFEPGTYLCDLEEHIKYRDFVH 2145
            + L +H+KDF+WVDEQDGDAI+LAFSKKKIEARKNWLRQFEPGTYL   E+ IKY DFV+
Sbjct: 655  KDLEKHRKDFMWVDEQDGDAIDLAFSKKKIEARKNWLRQFEPGTYLDQKEKLIKYSDFVN 714

Query: 2146 KELILFSIADLQRSIPSMVDGLKPGQRKILFCSFKRNFIKEAKVAQFSGYVSEHSAYHHG 2325
            KELILFS+ADLQRSIPSMVDGLKPGQRKILFCSFKRNF+KEAKVAQFSGYVSEHSAYHHG
Sbjct: 715  KELILFSMADLQRSIPSMVDGLKPGQRKILFCSFKRNFVKEAKVAQFSGYVSEHSAYHHG 774

Query: 2326 EQSLASTIIGMAQDYVGSNNINLLLPNGQFGTRGQGGKDHASARYIYTQLSSITRFLFPK 2505
            EQSLA TIIGMAQDYVGSNNINLL PNGQFGTR QGGKDHASARYIYT+LS ITRFLFPK
Sbjct: 775  EQSLAGTIIGMAQDYVGSNNINLLQPNGQFGTRHQGGKDHASARYIYTRLSPITRFLFPK 834

Query: 2506 ADDFLLNYLNEDGQSIEPTWYVPTIPMVLVNGSEGIGTGWSTFIPNYNPLDIIANVRHLL 2685
             DD LL+YLNEDGQSIEPTWYVP IP VLVNGSEGIGTGWS +IPNYNP DI+ NV+ LL
Sbjct: 835  DDDILLDYLNEDGQSIEPTWYVPVIPTVLVNGSEGIGTGWSCYIPNYNPRDIVENVKRLL 894

Query: 2686 NDEPMEPMHPWYKGFIGSIEKTATKEAGNSYTVSGIIEEVDETSLRITELPIRKWTQDYK 2865
            N EPMEPM PWYKGF G IEKTATKE G SYTVSGIIEEV+ET+LRI+ELP+R+WTQDYK
Sbjct: 895  NGEPMEPMDPWYKGFKGRIEKTATKEGGVSYTVSGIIEEVNETTLRISELPVRRWTQDYK 954

Query: 2866 EFLESVSAENDKSKDPFIEGCRDNSGGEIVHFSVYMSPNNLSEAKQEGLMKKFKLTTSIS 3045
            EFLES+   NDK K+PFI+  R+++    VHF V +S  NL  AKQEGL+KKFKLTT++S
Sbjct: 955  EFLESIMTGNDKIKEPFIKDYREHNDDTTVHFEVILSEENLVMAKQEGLLKKFKLTTTVS 1014

Query: 3046 TSNMHLFDSKGVIKKYDTPEQIIEEFFHIRLEFYDKRKKALLANLENDMLKCDNKYRFIR 3225
            TSNMHLFD KGVIKKYD PEQI+EEFFH+RLEFY+KRK+ LL NLE ++LK DNK RFI 
Sbjct: 1015 TSNMHLFDPKGVIKKYDNPEQILEEFFHLRLEFYEKRKRVLLENLELELLKLDNKVRFIL 1074

Query: 3226 GVVDGSIIVSNRKRADLFLELKEKGFTPFPKKKTAAEIAIAGSTDDADESEENNDVAIGK 3405
            GVV G IIVSNRKRADLFLEL++KGFTPFPKK    E  +AG+T+D +E+E+N++    +
Sbjct: 1075 GVVKGEIIVSNRKRADLFLELQQKGFTPFPKKTKLVEAVVAGATEDTEENEDNSEALSSR 1134

Query: 3406 GVSASDYDYLLSLAIGTLTAEKMKELRDERDKLMQEVEELKRATVKSLWMHDLDALESKF 3585
            GV ASDY+YLLS+AIGTLT EK++EL +++ +L  EV+EL+RAT KSLW  DLDALE +F
Sbjct: 1135 GVRASDYEYLLSMAIGTLTLEKVQELCNDKQRLDGEVDELRRATSKSLWKKDLDALEKEF 1194

Query: 3586 IEELNKSEKKWAENRQ----RILGEA--KGTRPVQTKPRK-NTKKASNKESVVEQMEVSD 3744
             +E +K++ K  E R+    +++ EA  K ++PV   PRK NTKK +N  +V    +VS 
Sbjct: 1195 -DEQDKNDSKAEEARKVMKSKVMKEAGMKDSKPVAKNPRKNNTKKVNNPAAVAASAQVS- 1252

Query: 3745 NTVTETDKVGEVXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXLRHRLAAYNFDSSP 3924
             +  E + + E                                   L+ RLAAYN DSSP
Sbjct: 1253 -STMEIENISEAAKPKGRGGPRKAPAKKGKPALVDSDDEDDDEILELKERLAAYNLDSSP 1311

Query: 3925 DRSE-----DMETEQPQMPTKKKEPNRRTAAQKKPLST--VSETXXXXXXXXXXXXXXXX 4083
            ++S       METE   +  K KE ++  +AQKK   T    +                 
Sbjct: 1312 EQSSAGPVAAMETESGIVRAKNKETSKMVSAQKKATITEISDDEDNRNDEQMKTIMENED 1371

Query: 4084 XXXXXXXXXXXXXXXXXXTKP--------PLAGTKKRGQQANKQQTQKLITEVLKPAEN- 4236
                              TKP        P+   +KRG    +   Q LIT++LKPAEN 
Sbjct: 1372 FEPEVVVPAGRKGGKRGQTKPAANPKAAKPVTVARKRGPTKKQLLNQTLITDILKPAENV 1431

Query: 4237 --SPEKKVRKMRASPFNKKSSSILGRTISVDXXXXXXXXXXXXNSVSTLGSVTEDVS--Q 4404
              SPEKKVRKMRASPFNKKS S+LGR    D               S +GS  +  S  +
Sbjct: 1432 GVSPEKKVRKMRASPFNKKSGSLLGRVAKED------------EEESPMGSEQQSGSSGE 1479

Query: 4405 AVAPKARPQRGTRGNARY 4458
             VA +ARPQR  R  A+Y
Sbjct: 1480 VVATRARPQRANRTVAKY 1497


>ref|XP_015881654.1| PREDICTED: DNA topoisomerase 2 isoform X2 [Ziziphus jujuba]
          Length = 1486

 Score = 1885 bits (4884), Expect = 0.0
 Identities = 972/1478 (65%), Positives = 1145/1478 (77%), Gaps = 14/1478 (0%)
 Frame = +1

Query: 67   MAGAKKAPLTTSNNANIPPSETVTAAGGK---KTIEQTYQKKTQLEHILLRPDTYIGSIE 237
            MA  KK PL +SNN N+ P    T  GG    KTIE+ YQKK+QLEHILLRPDTYIGSIE
Sbjct: 1    MAVDKKRPLQSSNNVNMAPPPLATTGGGNGPAKTIEEMYQKKSQLEHILLRPDTYIGSIE 60

Query: 238  KHTQTLWVYENEQMVQKSITFVPGLYKIFDEILVNAADNKQRDPKMDSVKVTIDVESSCI 417
            KHTQTLWVY+N++MV +S+T+VPGLYKIFDEILVNAADNKQRDP MDS+KV IDVE +CI
Sbjct: 61   KHTQTLWVYQNDEMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMDSLKVIIDVEQNCI 120

Query: 418  SVYNNGDGVPVEIHQEEGVYVPELIFGHLLTSSNYDDNEKKTTGGRNGYGAKLTNIFSTE 597
            SVYNNGDGVPVEIHQEE VYVPELIFGHLLTSSNYDD  KKTTGGRNGYGAKLTNIFSTE
Sbjct: 121  SVYNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTVKKTTGGRNGYGAKLTNIFSTE 180

Query: 598  FVIETADGKRQRKYKQVFSNNMGTKTEPIISKCKAGENWTRITFKPDLVKFSMSYLEEDV 777
            F+IETADGKRQ+KYKQVFS+NMG K+EP+I+KCK GENWT++TFKPDL KF+M++LE+DV
Sbjct: 181  FLIETADGKRQKKYKQVFSDNMGKKSEPVITKCKEGENWTKVTFKPDLGKFNMTHLEDDV 240

Query: 778  VALMKKRVIDVAGCLGKTVKVELNGQLFHFKSFSNYCDLYMKSTSVSTLDPLPRFEEEVH 957
            VALMKKRVID+AGCLGKTVKVELNG+    K+F +Y DLY++S   S    LPR  E V+
Sbjct: 241  VALMKKRVIDMAGCLGKTVKVELNGRRVPVKTFLDYVDLYLQSARKSRDVTLPRITERVN 300

Query: 958  DRWQVCISRSEGQFQQVSFVNGIATVKGGTHVDYVTNKITSHLVSVIXXXXXXXXXFDLK 1137
            DRW++C+S S+GQFQQVSFVN IAT+KGGTHVDY+TN+IT+H+++V+          ++K
Sbjct: 301  DRWEICVSLSDGQFQQVSFVNSIATIKGGTHVDYITNQITNHVMNVVNKKNKNA---NVK 357

Query: 1138 PHTVKNHLWVFVNALIDNPAFDSQTKETLTLRAASFGSSWDFSSKFLDKVAKSDIMKNIE 1317
             H VKN+LWVFV+ALIDNPAFDSQTKETLT+R +SFGS  +   +FL KVAKS I+ ++ 
Sbjct: 358  AHNVKNYLWVFVSALIDNPAFDSQTKETLTIRPSSFGSKCELPPEFLKKVAKSGIVDSLL 417

Query: 1318 EWAEFKQKKDLKKTDGSKDRRIYGLAKLADANEAGGKNSEKCTLILTEGDSAKALAIAGL 1497
             WA FK  KDLKKTDG+K  R++ + KL DANEAGG+NS+KCTLILTEGDSAKALA+AGL
Sbjct: 418  SWANFKNNKDLKKTDGTKTERVHNINKLEDANEAGGRNSDKCTLILTEGDSAKALAMAGL 477

Query: 1498 SVVGRDHYGVFPLRGKLLNVREASHNQLMQNVEIQHIKQILGLQHGKQYDSVKPLRYGHL 1677
            SVVGRD YGVFPLRGKLLNVREAS NQ+  N EI++IK+ILGLQ  K+Y +VK LRYGHL
Sbjct: 478  SVVGRDRYGVFPLRGKLLNVREASSNQVRDNEEIKNIKRILGLQQDKEYTNVKSLRYGHL 537

Query: 1678 MIMTDQDHDGSHIKGLLINFIHSFWPSLLKVPTFLLEFITPIVKATHRDGKRKESFYTMP 1857
            MIMTDQDHDGSHIKGLLINFIHSFWPSLLKVP+FL+EFITPIVKATH++GK   +FYTMP
Sbjct: 538  MIMTDQDHDGSHIKGLLINFIHSFWPSLLKVPSFLVEFITPIVKATHKNGKEL-AFYTMP 596

Query: 1858 QYETWKQNQGTDVKNWTIKYYKGLGTSTDQEAKEYFEALGRHKKDFVWVDEQDGDAIELA 2037
            QYE+W+++   +   W+IKYYKGLGTST +E +EYF+ L +H+KDF+WVD+QDG AIELA
Sbjct: 597  QYESWRESLRGNASGWSIKYYKGLGTSTSKEGREYFQNLDKHRKDFLWVDDQDGAAIELA 656

Query: 2038 FSKKKIEARKNWLRQFEPGTYLCDLEEHIKYRDFVHKELILFSIADLQRSIPSMVDGLKP 2217
            FSKKKIE RKNWLRQFEPGT+L   E+ IKY DFVHKELILFS+ADLQRSIPSMVDGLKP
Sbjct: 657  FSKKKIEERKNWLRQFEPGTHLDQKEKLIKYSDFVHKELILFSVADLQRSIPSMVDGLKP 716

Query: 2218 GQRKILFCSFKRNFIKEAKVAQFSGYVSEHSAYHHGEQSLASTIIGMAQDYVGSNNINLL 2397
            GQRKILFCSFKRNF KEAKVAQFSGYVSEHSAYHHGEQSLASTIIGMAQDYVGSNNINLL
Sbjct: 717  GQRKILFCSFKRNFFKEAKVAQFSGYVSEHSAYHHGEQSLASTIIGMAQDYVGSNNINLL 776

Query: 2398 LPNGQFGTRGQGGKDHASARYIYTQLSSITRFLFPKADDFLLNYLNEDGQSIEPTWYVPT 2577
             PNGQFGTR  GGKDHASARYI+T+LS ITRFLFPK DD LL+YLNEDGQ+IEPTWYVP 
Sbjct: 777  QPNGQFGTRNLGGKDHASARYIFTRLSPITRFLFPKDDDKLLDYLNEDGQTIEPTWYVPI 836

Query: 2578 IPMVLVNGSEGIGTGWSTFIPNYNPLDIIANVRHLLNDEPMEPMHPWYKGFIGSIEKTAT 2757
            IP VLVNGSEGIGTGWS++IPNYNP DI+AN+R LLN   M PM PWY+GF G+IEKT  
Sbjct: 837  IPTVLVNGSEGIGTGWSSYIPNYNPRDIVANIRRLLNGHSMVPMDPWYRGFKGTIEKTV- 895

Query: 2758 KEAGNSYTVSGIIEEVDETSLRITELPIRKWTQDYKEFLESVSAENDKSKDPFIEGCRDN 2937
            KEAG SYT+SGI+EEV+ET++RITELPIRKWTQDYKEFLES+S  NDK+KDPFIEG   +
Sbjct: 896  KEAGVSYTISGILEEVNETTIRITELPIRKWTQDYKEFLESISQGNDKAKDPFIEGFTQH 955

Query: 2938 SGGEIVHFSVYMSPNNLSEAKQEGLMKKFKLTTSISTSNMHLFDSKGVIKKYDTPEQIIE 3117
            S    V   V+M   NL  AKQEGL+KKFKLTT+ISTSNMHLFD+KGVIKKYDTPEQI+E
Sbjct: 956  SDHITVDILVHMPEENLVAAKQEGLLKKFKLTTTISTSNMHLFDAKGVIKKYDTPEQILE 1015

Query: 3118 EFFHIRLEFYDKRKKALLANLENDMLKCDNKYRFIRGVVDGSIIVSNRKRADLFLELKEK 3297
            EFFH+RLEFY+KRK+ LL NLE ++LK +NK RFI GVV+  IIVSNRKRADLFLEL++K
Sbjct: 1016 EFFHLRLEFYEKRKQVLLDNLEMELLKLENKVRFILGVVNEEIIVSNRKRADLFLELQQK 1075

Query: 3298 GFTPFPKKKTAAEIAIAGSTDDADESEENNDVAIGKGVSASDYDYLLSLAIGTLTAEKMK 3477
            GFTPFPKK  + E  +AG+TD  +E+E+N++     GV  SDY+YLLS+AIGTLT EK++
Sbjct: 1076 GFTPFPKKAKSVEPEVAGATDYTEETEDNSNP---DGVRISDYEYLLSMAIGTLTLEKVQ 1132

Query: 3478 ELRDERDKLMQEVEELKRATVKSLWMHDLDALESKFIEELNKSEKKWAENRQRI---LGE 3648
             L  ERDKL  EV++L++AT KSLW  DLDAL+ K ++EL+K++ +  + R+++   L  
Sbjct: 1133 ALCAERDKLNGEVDDLRKATPKSLWEKDLDALD-KELDELDKNDAQAEDARKKLKSQLNP 1191

Query: 3649 AKGTRPVQT--KPRKNTKKASNKESVVEQMEVSDNTVTETDKVGEVXXXXXXXXXXXXXX 3822
            A  T+  +    PRKN KKA+N E+VVE ME + ++  E +K  EV              
Sbjct: 1192 AAVTKFAKAPKNPRKNNKKANNAEAVVEMMETTSSSTMEMEKAPEVVKPKGRAVSRKAPT 1251

Query: 3823 XXXXXXXXXXXXXXXXXXXXLRHRLAAYNFDSSPDRSEDMETEQPQMPTKKKEPNRRTAA 4002
                                L+ RLAAYN +SSPDR  DME+E PQ+P +KKEP +R AA
Sbjct: 1252 KKEKPAVILDDDDDDDEVLELKERLAAYNLESSPDRPADMESEAPQVPVQKKEPTKRAAA 1311

Query: 4003 QKKPLSTVSETXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXTKPPLAGTKKRGQQA 4182
            QKK    ++                                    +KP  A  K+    A
Sbjct: 1312 QKKASVNLTTISDDEDESFDEDFELETEAAAKKKGGRKAAANTKASKPNAAAAKRGA--A 1369

Query: 4183 NKQQT---QKLITEVLKPAENS---PEKKVRKMRASPFNKKSSSILGRTISVDXXXXXXX 4344
            NKQ     Q+L+TE+LKPAE S   PEKKVRKMRASPFNKKSSS+LGR  + D       
Sbjct: 1370 NKQPRTLGQRLVTEMLKPAETSGISPEKKVRKMRASPFNKKSSSMLGRVANEDDEATGSE 1429

Query: 4345 XXXXXNSVSTLGSVTEDVSQAVAPKARPQRGTRGNARY 4458
                  S       TE+  +  A +ARPQR  R  ARY
Sbjct: 1430 DMSV--SPPPTFDDTEEGMEVPATRARPQRANRTQARY 1465


>ref|XP_015881653.1| PREDICTED: DNA topoisomerase 2 isoform X1 [Ziziphus jujuba]
          Length = 1487

 Score = 1881 bits (4872), Expect = 0.0
 Identities = 976/1482 (65%), Positives = 1148/1482 (77%), Gaps = 18/1482 (1%)
 Frame = +1

Query: 67   MAGAKKAPLTTSNNANIPPSETVTAAGGK---KTIEQTYQKKTQLEHILLRPDTYIGSIE 237
            MA  KK PL +SNN N+ P    T  GG    KTIE+ YQKK+QLEHILLRPDTYIGSIE
Sbjct: 1    MAVDKKRPLQSSNNVNMAPPPLATTGGGNGPAKTIEEMYQKKSQLEHILLRPDTYIGSIE 60

Query: 238  KHTQTLWVYENEQMVQKSITFVPGLYKIFDEILVNAADNKQRDPKMDSVKVTIDVESSCI 417
            KHTQTLWVY+N++MV +S+T+VPGLYKIFDEILVNAADNKQRDP MDS+KV IDVE +CI
Sbjct: 61   KHTQTLWVYQNDEMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMDSLKVIIDVEQNCI 120

Query: 418  SVYNNGDGVPVEIHQEEGVYVPELIFGHLLTSSNYDDNEKKTTGGRNGYGAKLTNIFSTE 597
            SVYNNGDGVPVEIHQEE VYVPELIFGHLLTSSNYDD  KKTTGGRNGYGAKLTNIFSTE
Sbjct: 121  SVYNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTVKKTTGGRNGYGAKLTNIFSTE 180

Query: 598  FVIETADGKRQRKYKQVFSNNMGTKTEPIISKCKAGENWTRITFKPDLVKFSMSYLEEDV 777
            F+IETADGKRQ+KYKQVFS+NMG K+EP+I+KCK GENWT++TFKPDL KF+M++LE+DV
Sbjct: 181  FLIETADGKRQKKYKQVFSDNMGKKSEPVITKCKEGENWTKVTFKPDLGKFNMTHLEDDV 240

Query: 778  VALMKKRVIDVAGCLGKTVKVELNGQLFHFKSFSNYCDLYMKSTSVSTLDPLPRFEEEVH 957
            VALMKKRVID+AGCLGKTVKVELNG+    K+F +Y DLY++S   S    LPR  E V+
Sbjct: 241  VALMKKRVIDMAGCLGKTVKVELNGRRVPVKTFLDYVDLYLQSARKSRDVTLPRITERVN 300

Query: 958  DRWQVCISRSEGQFQQVSFVNGIATVKGGTHVDYVTNKITSHLVSVIXXXXXXXXXFDLK 1137
            DRW++C+S S+GQFQQVSFVN IAT+KGGTHVDY+TN+IT+H+++V+          ++K
Sbjct: 301  DRWEICVSLSDGQFQQVSFVNSIATIKGGTHVDYITNQITNHVMNVVNKKNKNA---NVK 357

Query: 1138 PHTVKNHLWVFVNALIDNPAFDSQTKETLTLRAASFGSSWDFSSKFLDKVAKSDIMKNIE 1317
             H VKN+LWVFV+ALIDNPAFDSQTKETLT+R +SFGS  +   +FL KVAKS I+ ++ 
Sbjct: 358  AHNVKNYLWVFVSALIDNPAFDSQTKETLTIRPSSFGSKCELPPEFLKKVAKSGIVDSLL 417

Query: 1318 EWAEFKQKKDLKKTDGSKDRRIYGLAKLADANEAGGKNSEKCTLILTEGDSAKALAIAGL 1497
             WA FK  KDLKKTDG+K  R++ + KL DANEAGG+NS+KCTLILTEGDSAKALA+AGL
Sbjct: 418  SWANFKNNKDLKKTDGTKTERVHNINKLEDANEAGGRNSDKCTLILTEGDSAKALAMAGL 477

Query: 1498 SVVGRDHYGVFPLRGKLLNVREASHNQLMQNVEIQHIKQILGLQHGKQYDSVKPLRYGHL 1677
            SVVGRD YGVFPLRGKLLNVREAS NQ+  N EI++IK+ILGLQ  K+Y +VK LRYGHL
Sbjct: 478  SVVGRDRYGVFPLRGKLLNVREASSNQVRDNEEIKNIKRILGLQQDKEYTNVKSLRYGHL 537

Query: 1678 MIMTDQDHDGSHIKGLLINFIHSFWPSLLKVPTFLLEFITPIVKATHRDGKRKESFYTMP 1857
            MIMTDQDHDGSHIKGLLINFIHSFWPSLLKVP+FL+EFITPIVKATH++GK + +FYTMP
Sbjct: 538  MIMTDQDHDGSHIKGLLINFIHSFWPSLLKVPSFLVEFITPIVKATHKNGK-ELAFYTMP 596

Query: 1858 QYETWKQNQGTDVKNWTIKYYKGLGTSTDQEAKEYFEALGRHKKDFVWVDEQDGDAIELA 2037
            QYE+W+++   +   W+IKYYKGLGTST +E +EYF+ L +H+KDF+WVD+QDG AIELA
Sbjct: 597  QYESWRESLRGNASGWSIKYYKGLGTSTSKEGREYFQNLDKHRKDFLWVDDQDGAAIELA 656

Query: 2038 FSKKKIEARKNWLRQFEPGTYLCDLEEHIKYRDFVHKELILFSIADLQRSIPSMVDGLKP 2217
            FSKKKIE RKNWLRQFEPGT+L   E+ IKY DFVHKELILFS+ADLQRSIPSMVDGLKP
Sbjct: 657  FSKKKIEERKNWLRQFEPGTHLDQKEKLIKYSDFVHKELILFSVADLQRSIPSMVDGLKP 716

Query: 2218 GQRKILFCSFKRNFIKEAKVAQFSGYVSEHSAYHHGEQSLASTIIGMAQDYVGSNNINLL 2397
            GQRKILFCSFKRNF KEAKVAQFSGYVSEHSAYHHGEQSLASTIIGMAQDYVGSNNINLL
Sbjct: 717  GQRKILFCSFKRNFFKEAKVAQFSGYVSEHSAYHHGEQSLASTIIGMAQDYVGSNNINLL 776

Query: 2398 LPNGQFGTRGQGGKDHASARYIYTQLSSITRFLFPKADDFLLNYLNEDGQSIEPTWYVPT 2577
             PNGQFGTR  GGKDHASARYI+T+LS ITRFLFPK DD LL+YLNEDGQ+IEPTWYVP 
Sbjct: 777  QPNGQFGTRNLGGKDHASARYIFTRLSPITRFLFPKDDDKLLDYLNEDGQTIEPTWYVPI 836

Query: 2578 IPMVLVNGSEGIGTGWSTFIPNYNPLDIIANVRHLLNDEPMEPMHPWYKGFIGSIEKTAT 2757
            IP VLVNGSEGIGTGWS++IPNYNP DI+AN+R LLN   M PM PWY+GF G+IEKT  
Sbjct: 837  IPTVLVNGSEGIGTGWSSYIPNYNPRDIVANIRRLLNGHSMVPMDPWYRGFKGTIEKT-V 895

Query: 2758 KEAGNSYTVSGIIEEVDETSLRITELPIRKWTQDYKEFLESVSAENDKSKDPFIEGCRDN 2937
            KEAG SYT+SGI+EEV+ET++RITELPIRKWTQDYKEFLES+S  NDK+KDPFIEG   +
Sbjct: 896  KEAGVSYTISGILEEVNETTIRITELPIRKWTQDYKEFLESISQGNDKAKDPFIEGFTQH 955

Query: 2938 SGGEIVHFSVYMSPNNLSEAKQEGLMKKFKLTTSISTSNMHLFDSKGVIKKYDTPEQIIE 3117
            S    V   V+M   NL  AKQEGL+KKFKLTT+ISTSNMHLFD+KGVIKKYDTPEQI+E
Sbjct: 956  SDHITVDILVHMPEENLVAAKQEGLLKKFKLTTTISTSNMHLFDAKGVIKKYDTPEQILE 1015

Query: 3118 EFFHIRLEFYDKRKKALLANLENDMLKCDNKYRFIRGVVDGSIIVSNRKRADLFLELKEK 3297
            EFFH+RLEFY+KRK+ LL NLE ++LK +NK RFI GVV+  IIVSNRKRADLFLEL++K
Sbjct: 1016 EFFHLRLEFYEKRKQVLLDNLEMELLKLENKVRFILGVVNEEIIVSNRKRADLFLELQQK 1075

Query: 3298 GFTPFPKKKTAAEIAIAGSTDDADESEENNDVAIGKGVSASDYDYLLSLAIGTLTAEKMK 3477
            GFTPFPKK  + E  +AG+TD  +E+E+N++     GV  SDY+YLLS+AIGTLT EK++
Sbjct: 1076 GFTPFPKKAKSVEPEVAGATDYTEETEDNSN---PDGVRISDYEYLLSMAIGTLTLEKVQ 1132

Query: 3478 ELRDERDKLMQEVEELKRATVKSLWMHDLDALESKFIEELNKSEKKWAENRQRI---LGE 3648
             L  ERDKL  EV++L++AT KSLW  DLDAL+ K ++EL+K++ +  + R+++   L  
Sbjct: 1133 ALCAERDKLNGEVDDLRKATPKSLWEKDLDALD-KELDELDKNDAQAEDARKKLKSQLNP 1191

Query: 3649 AKGTR--PVQTKPRKNTKKASNKESVVEQMEVSDNTVTETDKVGE-VXXXXXXXXXXXXX 3819
            A  T+       PRKN KKA+N E+VVE ME + ++  E +K  E V             
Sbjct: 1192 AAVTKFAKAPKNPRKNNKKANNAEAVVEMMETTSSSTMEMEKAPEVVKPKGRAVSRKAPT 1251

Query: 3820 XXXXXXXXXXXXXXXXXXXXXLRHRLAAYNFDSSPDRSEDMETEQPQMPTKKKEPNRRTA 3999
                                 L+ RLAAYN +SSPDR  DME+E PQ+P +KKEP +R A
Sbjct: 1252 KKQEKPAVILDDDDDDDEVLELKERLAAYNLESSPDRPADMESEAPQVPVQKKEPTKRAA 1311

Query: 4000 AQKKP---LSTVSETXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXTKPPLAGTKKR 4170
            AQKK    L+T+S+                                      P A   KR
Sbjct: 1312 AQKKASVNLTTISD----DEDESFDEDFELETEAAAKKKGGRKAAANTKASKPNAAAAKR 1367

Query: 4171 GQQANKQQT---QKLITEVLKPAEN---SPEKKVRKMRASPFNKKSSSILGRTISVDXXX 4332
            G  ANKQ     Q+L+TE+LKPAE    SPEKKVRKMRASPFNKKSSS+LGR  + D   
Sbjct: 1368 G-AANKQPRTLGQRLVTEMLKPAETSGISPEKKVRKMRASPFNKKSSSMLGRVANEDDEA 1426

Query: 4333 XXXXXXXXXNSVSTLGSVTEDVSQAVAPKARPQRGTRGNARY 4458
                      S       TE+  +  A +ARPQR  R  ARY
Sbjct: 1427 TGSEDMSV--SPPPTFDDTEEGMEVPATRARPQRANRTQARY 1466


>gb|EOY18137.1| DNA topoisomerase 2 isoform 1 [Theobroma cacao]
          Length = 1473

 Score = 1878 bits (4864), Expect = 0.0
 Identities = 968/1478 (65%), Positives = 1137/1478 (76%), Gaps = 14/1478 (0%)
 Frame = +1

Query: 67   MAGAKKAPLTTSNNANIPPSETVTAAGGKKTIEQTYQKKTQLEHILLRPDTYIGSIEKHT 246
            M    K PL +SNNAN+  S         KTIE+TYQKKTQLEHILLRPDTYIGSIE+HT
Sbjct: 1    MVADSKLPLQSSNNANMKAS---------KTIEETYQKKTQLEHILLRPDTYIGSIEQHT 51

Query: 247  QTLWVYENEQMVQKSITFVPGLYKIFDEILVNAADNKQRDPKMDSVKVTIDVESSCISVY 426
            Q LWVYEN++MV + I +VPGLYKIFDEILVNAADNKQRDP MDSVKV ID E + ISVY
Sbjct: 52   QRLWVYENDEMVHRDIKYVPGLYKIFDEILVNAADNKQRDPSMDSVKVVIDAEQNLISVY 111

Query: 427  NNGDGVPVEIHQEEGVYVPELIFGHLLTSSNYDDNEKKTTGGRNGYGAKLTNIFSTEFVI 606
            NNGDGVPVE+HQEEGVYVPELIFGHLLTSSNYDD  KKTTGGRNGYGAKLTNIFSTEF+I
Sbjct: 112  NNGDGVPVEVHQEEGVYVPELIFGHLLTSSNYDDTVKKTTGGRNGYGAKLTNIFSTEFII 171

Query: 607  ETADGKRQRKYKQVFSNNMGTKTEPIISKCKAGENWTRITFKPDLVKFSMSYLEEDVVAL 786
            ETADGKRQ+KYKQVFSNNMG K+EP+ISKCK  ENWT++TFKPDL KF+M++LEEDVVAL
Sbjct: 172  ETADGKRQKKYKQVFSNNMGKKSEPVISKCKEAENWTKVTFKPDLAKFNMTHLEEDVVAL 231

Query: 787  MKKRVIDVAGCLGKTVKVELNGQLFHFKSFSNYCDLYMKSTSVSTLDPLPRFEEEVHDRW 966
            MKKRV DVAGCLGKTVKVELNG+    KSF +Y  LY+ + S +  +PLPR  E+V++RW
Sbjct: 232  MKKRVFDVAGCLGKTVKVELNGKRVPVKSFLDYVSLYLSAASKTKTEPLPRLLEKVNERW 291

Query: 967  QVCISRSEGQFQQVSFVNGIATVKGGTHVDYVTNKITSHLVSVIXXXXXXXXXFDLKPHT 1146
            +V +S S+GQFQQVSFVNGIAT+KGGTHVDYVTN+I++++++++          ++K H 
Sbjct: 292  EVGVSLSDGQFQQVSFVNGIATIKGGTHVDYVTNQISNYVMNIVNKKNKNA---NVKAHN 348

Query: 1147 VKNHLWVFVNALIDNPAFDSQTKETLTLRAASFGSSWDFSSKFLDKVAKSDIMKNIEEWA 1326
            VKNHLWVFVNALIDNPAFDSQTKETLTLR +SFGS  + S  FL KVAK  ++ N+  WA
Sbjct: 349  VKNHLWVFVNALIDNPAFDSQTKETLTLRQSSFGSKCELSEDFLKKVAKCGVVDNLLSWA 408

Query: 1327 EFKQKKDLKKTDGSKDRRIYGLAKLADANEAGGKNSEKCTLILTEGDSAKALAIAGLSVV 1506
            EFK  KDLKKTDG+K   I G+ KL DANEAGG+NS+KCTLILTEGDSAKALA+AGL+VV
Sbjct: 409  EFKHSKDLKKTDGAKTGSIRGIPKLDDANEAGGRNSDKCTLILTEGDSAKALAVAGLAVV 468

Query: 1507 GRDHYGVFPLRGKLLNVREASHNQLMQNVEIQHIKQILGLQHGKQYDSVKPLRYGHLMIM 1686
            GR+HYGVFPLRGKLLNVREASH QLM N EIQ++K+ILGLQ GK+Y +VK LRYGHLMIM
Sbjct: 469  GRNHYGVFPLRGKLLNVREASHKQLMDNAEIQNLKRILGLQQGKEYSNVKSLRYGHLMIM 528

Query: 1687 TDQDHDGSHIKGLLINFIHSFWPSLLKVPTFLLEFITPIVKATHRDGKRKESFYTMPQYE 1866
            TDQDHDGSHIKGLLINFIHSFWPSLLKVP+F++EFITPIVKATH+  K   SFY+MP+YE
Sbjct: 529  TDQDHDGSHIKGLLINFIHSFWPSLLKVPSFMVEFITPIVKATHKT-KGVLSFYSMPEYE 587

Query: 1867 TWKQNQGTDVKNWTIKYYKGLGTSTDQEAKEYFEALGRHKKDFVWVDEQDGDAIELAFSK 2046
             WK++ G + K W+IKYYKGLGTST +E K+YF+ L +H+K+FVW DEQDG+AIELAFSK
Sbjct: 588  FWKESLGGNAKGWSIKYYKGLGTSTSKEGKDYFKNLDKHRKEFVWQDEQDGEAIELAFSK 647

Query: 2047 KKIEARKNWLRQFEPGTYLCDLEEHIKYRDFVHKELILFSIADLQRSIPSMVDGLKPGQR 2226
            KKIEARKNWLRQFEPGT+L   ++ IKY +F++KELILFS+ADLQRSIPSM+DGLKPGQR
Sbjct: 648  KKIEARKNWLRQFEPGTHLDQSQKLIKYSEFINKELILFSMADLQRSIPSMIDGLKPGQR 707

Query: 2227 KILFCSFKRNFIKEAKVAQFSGYVSEHSAYHHGEQSLASTIIGMAQDYVGSNNINLLLPN 2406
            KILFCSFKRNF+KEAKVAQFSGYVSEHSAYHHGEQSLASTI+GMAQD+VGSNNINLL P 
Sbjct: 708  KILFCSFKRNFVKEAKVAQFSGYVSEHSAYHHGEQSLASTIVGMAQDFVGSNNINLLNPG 767

Query: 2407 GQFGTRGQGGKDHASARYIYTQLSSITRFLFPKADDFLLNYLNEDGQSIEPTWYVPTIPM 2586
            GQFGTR QGGKD ASARYI+T LS ITR+LFPK DD LL+YLNEDGQSIEP WYVP IPM
Sbjct: 768  GQFGTRNQGGKDAASARYIFTNLSPITRYLFPKDDDGLLDYLNEDGQSIEPIWYVPIIPM 827

Query: 2587 VLVNGSEGIGTGWSTFIPNYNPLDIIANVRHLLNDEPMEPMHPWYKGFIGSIEKTATKEA 2766
            VLVNGSEGIGTGWS++IPNYNP DI+ANVR LLN E MEPMHPWY+GF G+IEKTA+KEA
Sbjct: 828  VLVNGSEGIGTGWSSYIPNYNPRDIVANVRRLLNGEQMEPMHPWYRGFKGNIEKTASKEA 887

Query: 2767 GNSYTVSGIIEEVDETSLRITELPIRKWTQDYKEFLESVSAENDKSKDPFIEGCRDNSGG 2946
            G +YT++GIIEEVDET+LRITELP+R+WTQDY+EFLES+   N    DPFI+  R  S  
Sbjct: 888  GVTYTITGIIEEVDETTLRITELPVRRWTQDYREFLESIITGN----DPFIKEFRQYSDD 943

Query: 2947 EIVHFSVYMSPNNLSEAKQEGLMKKFKLTTSISTSNMHLFDSKGVIKKYDTPEQIIEEFF 3126
              V F V ++  N+  AKQEGL+KKFKLTT+ISTSNMHLFDSKG+IKKYDTPEQI+EEFF
Sbjct: 944  TTVEFEVILTEENMMVAKQEGLLKKFKLTTTISTSNMHLFDSKGMIKKYDTPEQILEEFF 1003

Query: 3127 HIRLEFYDKRKKALLANLENDMLKCDNKYRFIRGVVDGSIIVSNRKRADLFLELKEKGFT 3306
            H+R EFY+KRKK LL NLE ++LK +NK RFI GVV G IIV+NRKRADLFLEL+ KGFT
Sbjct: 1004 HLRFEFYEKRKKLLLDNLEMELLKMENKVRFILGVVKGEIIVNNRKRADLFLELQTKGFT 1063

Query: 3307 PFPKKKTAAEIAIAGSTDDADESEENNDVAIGKGVSASDYDYLLSLAIGTLTAEKMKELR 3486
            PFPKK    E+A+AG+TDD +E+EEN++V+  KG+ ASDYDYLLS+AIG+LT EK++EL 
Sbjct: 1064 PFPKKAKTVEVAVAGATDDTEETEENSEVS-AKGLQASDYDYLLSMAIGSLTLEKVQELC 1122

Query: 3487 DERDKLMQEVEELKRATVKSLWMHDLDALESKFIEELNKSEKKWAENRQRILGEA--KGT 3660
             +RDKL QEVE+L++AT KSLW+ DLD LE +  E+   ++ + A    +  GEA  +  
Sbjct: 1123 ADRDKLQQEVEDLRKATPKSLWLKDLDNLEIQLDEQDKAAQAEEAAKLVKGRGEAGKRAQ 1182

Query: 3661 RPVQTKPRKNTKKASNKESVVEQMEVSDNTVTETDKVGEVXXXXXXXXXXXXXXXXXXXX 3840
            R     PRK  KK  N E+V E  ++S ++  ET+                         
Sbjct: 1183 RQAPKIPRKINKKEKNAETVTETTDISSSSAMETETA-----PAAVKPKGRGGSRKAKKD 1237

Query: 3841 XXXXXXXXXXXXXXLRHRLAAYNFDSSPDRSEDMETEQPQMPTKKKEPNRR-TAAQKKP- 4014
                          LR RLA YN DSSPD S  METE PQ+P  KKEP++R  AA+KKP 
Sbjct: 1238 DSDDDDDEDFGIPDLRERLAKYNLDSSPDHSAAMETEVPQVPAGKKEPSKRAAAARKKPA 1297

Query: 4015 --LSTVSETXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXTK---PPLAGTKKRGQQ 4179
              LS +SE+                                  +K    P A  KKRG  
Sbjct: 1298 TSLSEISESIGEIDINDEDLEVVEVAAAAAPAGKKGGRKPAANSKAAAKPPAAAKKRGPA 1357

Query: 4180 A--NKQQTQKLITEVLKPAEN---SPEKKVRKMRASPFNKKSSSILGRTISVDXXXXXXX 4344
            A   K Q QKL+TE+LKPAE+   SPEKKVRKMRASPFNKKS S+LGR   V        
Sbjct: 1358 AAGKKSQQQKLLTEMLKPAEDSGISPEKKVRKMRASPFNKKSGSVLGR---VGKELESTT 1414

Query: 4345 XXXXXNSVSTLGSVTEDVSQAVAPKARPQRGTRGNARY 4458
                    S++ + TE+V++ V  + RPQR  R    Y
Sbjct: 1415 DSEETFGSSSMSADTEEVTEIVPARPRPQRTNRKQTTY 1452


>ref|XP_007009327.2| PREDICTED: DNA topoisomerase 2 [Theobroma cacao]
          Length = 1473

 Score = 1875 bits (4856), Expect = 0.0
 Identities = 967/1478 (65%), Positives = 1135/1478 (76%), Gaps = 14/1478 (0%)
 Frame = +1

Query: 67   MAGAKKAPLTTSNNANIPPSETVTAAGGKKTIEQTYQKKTQLEHILLRPDTYIGSIEKHT 246
            M    K PL +SNNAN+  S         KTIE+TYQKKTQLEHILLRPDTYIGSIE+HT
Sbjct: 1    MVADSKLPLQSSNNANMKAS---------KTIEETYQKKTQLEHILLRPDTYIGSIEQHT 51

Query: 247  QTLWVYENEQMVQKSITFVPGLYKIFDEILVNAADNKQRDPKMDSVKVTIDVESSCISVY 426
            Q LWVYEN++MV + I +VPGLYKIFDEILVNAADNKQRDP MDSVKV ID E + ISVY
Sbjct: 52   QRLWVYENDEMVHRDIKYVPGLYKIFDEILVNAADNKQRDPSMDSVKVVIDAEQNLISVY 111

Query: 427  NNGDGVPVEIHQEEGVYVPELIFGHLLTSSNYDDNEKKTTGGRNGYGAKLTNIFSTEFVI 606
            NNGDGVPVE+HQEEGVYVPELIFGHLLTSSNYDD  KKTTGGRNGYGAKLTNIFSTEF+I
Sbjct: 112  NNGDGVPVEVHQEEGVYVPELIFGHLLTSSNYDDTVKKTTGGRNGYGAKLTNIFSTEFII 171

Query: 607  ETADGKRQRKYKQVFSNNMGTKTEPIISKCKAGENWTRITFKPDLVKFSMSYLEEDVVAL 786
            ETADGKRQ+KYKQVFSNNMG K+EP+ISKCK  ENWT++TFKPDL KF+M++LEEDVVAL
Sbjct: 172  ETADGKRQKKYKQVFSNNMGKKSEPVISKCKEAENWTKVTFKPDLAKFNMTHLEEDVVAL 231

Query: 787  MKKRVIDVAGCLGKTVKVELNGQLFHFKSFSNYCDLYMKSTSVSTLDPLPRFEEEVHDRW 966
            MKKRV DVAGCLGKTVKVELNG+    KSF +Y  LY+ + S +  +PLPR  E+V++RW
Sbjct: 232  MKKRVFDVAGCLGKTVKVELNGKRVPVKSFLDYVSLYLSAASKTKTEPLPRLLEKVNERW 291

Query: 967  QVCISRSEGQFQQVSFVNGIATVKGGTHVDYVTNKITSHLVSVIXXXXXXXXXFDLKPHT 1146
            +V +S S+GQFQQVSFVNGIAT+KGGTHVDYVTN+I++++++++          ++K H 
Sbjct: 292  EVGVSLSDGQFQQVSFVNGIATIKGGTHVDYVTNQISNYVMNIVNKKNKNA---NVKAHN 348

Query: 1147 VKNHLWVFVNALIDNPAFDSQTKETLTLRAASFGSSWDFSSKFLDKVAKSDIMKNIEEWA 1326
            VKNHLWVFVNALIDNPAFDSQTKETLTLR +SFGS  + S  FL KVAK  ++ N+  WA
Sbjct: 349  VKNHLWVFVNALIDNPAFDSQTKETLTLRQSSFGSKCELSEDFLKKVAKCGVVDNLLSWA 408

Query: 1327 EFKQKKDLKKTDGSKDRRIYGLAKLADANEAGGKNSEKCTLILTEGDSAKALAIAGLSVV 1506
            EFK  KDLKKTDG+K   I G+ KL DANEAGG+NS+KCTLILTEGDSAKALA+AGL+VV
Sbjct: 409  EFKHSKDLKKTDGAKTGSIRGIPKLDDANEAGGRNSDKCTLILTEGDSAKALAVAGLAVV 468

Query: 1507 GRDHYGVFPLRGKLLNVREASHNQLMQNVEIQHIKQILGLQHGKQYDSVKPLRYGHLMIM 1686
            GR+HYGVFPLRGKLLNVREASH QLM N EIQ++K+ILGLQ GK+Y +VK LRYGHLMIM
Sbjct: 469  GRNHYGVFPLRGKLLNVREASHKQLMDNAEIQNLKRILGLQQGKEYSNVKSLRYGHLMIM 528

Query: 1687 TDQDHDGSHIKGLLINFIHSFWPSLLKVPTFLLEFITPIVKATHRDGKRKESFYTMPQYE 1866
            TDQDHDGSHIKGLLINFIHSFWPSLLKVP+F++EFITPIVKATH+  K   SFY+MP+YE
Sbjct: 529  TDQDHDGSHIKGLLINFIHSFWPSLLKVPSFMVEFITPIVKATHKT-KGVLSFYSMPEYE 587

Query: 1867 TWKQNQGTDVKNWTIKYYKGLGTSTDQEAKEYFEALGRHKKDFVWVDEQDGDAIELAFSK 2046
             WK++ G + K W+IKYYKGLGTST +E K+YF+ L +H+K+FVW DEQDG+AIELAFSK
Sbjct: 588  FWKESLGGNAKGWSIKYYKGLGTSTSKEGKDYFKNLDKHRKEFVWQDEQDGEAIELAFSK 647

Query: 2047 KKIEARKNWLRQFEPGTYLCDLEEHIKYRDFVHKELILFSIADLQRSIPSMVDGLKPGQR 2226
            KKIEARKNWLRQFEPGT+L   ++ IKY +F++KELILFS+ADLQRSIPSM+DGLKPGQR
Sbjct: 648  KKIEARKNWLRQFEPGTHLDQSQKLIKYSEFINKELILFSMADLQRSIPSMIDGLKPGQR 707

Query: 2227 KILFCSFKRNFIKEAKVAQFSGYVSEHSAYHHGEQSLASTIIGMAQDYVGSNNINLLLPN 2406
            KILFCSFKRNF+KEAKVAQFSGYVSEHSAYHHGEQSLASTI+GMAQD+VGSNNINLL P 
Sbjct: 708  KILFCSFKRNFVKEAKVAQFSGYVSEHSAYHHGEQSLASTIVGMAQDFVGSNNINLLHPG 767

Query: 2407 GQFGTRGQGGKDHASARYIYTQLSSITRFLFPKADDFLLNYLNEDGQSIEPTWYVPTIPM 2586
            GQFGTR QGGKD ASARYI+T LS ITR+LFPK DD LL+YLNEDGQSIEP WYVP IPM
Sbjct: 768  GQFGTRNQGGKDAASARYIFTNLSPITRYLFPKDDDGLLDYLNEDGQSIEPIWYVPIIPM 827

Query: 2587 VLVNGSEGIGTGWSTFIPNYNPLDIIANVRHLLNDEPMEPMHPWYKGFIGSIEKTATKEA 2766
            VLVNGSEGIGTGWS++IPNYNP DI+ANVR LLN E MEPMHPWY+GF G+IEKTA+KEA
Sbjct: 828  VLVNGSEGIGTGWSSYIPNYNPRDIVANVRRLLNGEQMEPMHPWYRGFKGNIEKTASKEA 887

Query: 2767 GNSYTVSGIIEEVDETSLRITELPIRKWTQDYKEFLESVSAENDKSKDPFIEGCRDNSGG 2946
            G +YT++GIIEEVDET+LRITELP+R+WTQDY+EFLES+   N    DPFI+  R  S  
Sbjct: 888  GVTYTITGIIEEVDETTLRITELPVRRWTQDYREFLESIITGN----DPFIKEFRQYSDD 943

Query: 2947 EIVHFSVYMSPNNLSEAKQEGLMKKFKLTTSISTSNMHLFDSKGVIKKYDTPEQIIEEFF 3126
              V F V ++  N+  AKQEGL+KKFKLTT+ISTSNMHLFDSKG+IKKYD PEQI+EEFF
Sbjct: 944  TTVEFEVILTEENMMMAKQEGLLKKFKLTTTISTSNMHLFDSKGMIKKYDAPEQILEEFF 1003

Query: 3127 HIRLEFYDKRKKALLANLENDMLKCDNKYRFIRGVVDGSIIVSNRKRADLFLELKEKGFT 3306
            H+R EFY+KRKK LL NLE ++LK +NK RFI GVV G IIV+NRKRADLFLEL+ KGFT
Sbjct: 1004 HLRFEFYEKRKKLLLDNLEMELLKMENKVRFILGVVKGEIIVNNRKRADLFLELQTKGFT 1063

Query: 3307 PFPKKKTAAEIAIAGSTDDADESEENNDVAIGKGVSASDYDYLLSLAIGTLTAEKMKELR 3486
            PFPKK    E+A+AG+TDD +E+EEN++V+  KGV ASDYDYLLS+AIG+LT EK++EL 
Sbjct: 1064 PFPKKAKTVEVAVAGATDDTEETEENSEVS-AKGVQASDYDYLLSMAIGSLTLEKVQELC 1122

Query: 3487 DERDKLMQEVEELKRATVKSLWMHDLDALESKFIEELNKSEKKWAENRQRILGEA--KGT 3660
             +RDKL QEVE+L++AT  SLW+ DLD LE +  E+   ++ + A    +  GEA  +  
Sbjct: 1123 ADRDKLQQEVEDLRKATPMSLWLKDLDNLEIQLDEQDKAAQAEEAAKLVKGRGEAGKRAQ 1182

Query: 3661 RPVQTKPRKNTKKASNKESVVEQMEVSDNTVTETDKVGEVXXXXXXXXXXXXXXXXXXXX 3840
            R     PRK  KK  N E+V E  ++S ++  ET+                         
Sbjct: 1183 RQAPKIPRKINKKEKNAETVTETTDISSSSAMETETA-----PAAVKPKGRGGSRKAKKD 1237

Query: 3841 XXXXXXXXXXXXXXLRHRLAAYNFDSSPDRSEDMETEQPQMPTKKKEPNRR-TAAQKKP- 4014
                          LR RLA YN DSSPD S  METE PQ+P  KKEP++R  AA+KKP 
Sbjct: 1238 DSDDDDDEDFGIPDLRERLAKYNLDSSPDHSAAMETEVPQVPAGKKEPSKRAAAARKKPA 1297

Query: 4015 --LSTVSETXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXTK---PPLAGTKKRGQQ 4179
              LS +SE+                                  +K    P A  KKRG  
Sbjct: 1298 TSLSEISESIGEIDINDEDLEVVEVAAAAAPAGKKGGRKPAANSKAAAKPPAAAKKRGPA 1357

Query: 4180 A--NKQQTQKLITEVLKPAEN---SPEKKVRKMRASPFNKKSSSILGRTISVDXXXXXXX 4344
            A   K Q QKL+TE+LKPAE+   SPEKKVRKMRASPFNKKS S+LGR   V        
Sbjct: 1358 AAGKKSQQQKLLTEMLKPAEDSGISPEKKVRKMRASPFNKKSGSVLGR---VGKELESTT 1414

Query: 4345 XXXXXNSVSTLGSVTEDVSQAVAPKARPQRGTRGNARY 4458
                    S++ + TE+V++ V  + RPQR  R    Y
Sbjct: 1415 DSEEAFGSSSMSADTEEVTEIVPARPRPQRTNRKQTTY 1452


>gb|OWM78385.1| hypothetical protein CDL15_Pgr016109 [Punica granatum]
 gb|PKI31894.1| hypothetical protein CRG98_047704 [Punica granatum]
          Length = 1473

 Score = 1872 bits (4848), Expect = 0.0
 Identities = 975/1482 (65%), Positives = 1140/1482 (76%), Gaps = 18/1482 (1%)
 Frame = +1

Query: 67   MAGAKKAPLTTSNNANIPPSETVTAAGGKKTIEQTYQKKTQLEHILLRPDTYIGSIEKHT 246
            MA AKK PL  SN  NI P+         KTIE+TYQKK+QLEHILLRPDTYIGSIEKHT
Sbjct: 1    MAAAKKLPLQNSNTVNIAPA---VPRAPHKTIEETYQKKSQLEHILLRPDTYIGSIEKHT 57

Query: 247  QTLWVYENEQMVQKSITFVPGLYKIFDEILVNAADNKQRDPKMDSVKVTIDVESSCISVY 426
            QT+WVYENE+MV + +T+VPGLYKIFDEILVNAADNKQRDP+MDSVKVTIDVE + ISVY
Sbjct: 58   QTMWVYENEEMVHRPVTYVPGLYKIFDEILVNAADNKQRDPRMDSVKVTIDVEHNLISVY 117

Query: 427  NNGDGVPVEIHQEEGVYVPELIFGHLLTSSNYDDNEKKTTGGRNGYGAKLTNIFSTEFVI 606
            NNGDGVPVEIHQEE VYVPELIFGHLLTSSNYDD+ KKTTGGRNGYGAKLTNIFSTEFVI
Sbjct: 118  NNGDGVPVEIHQEEQVYVPELIFGHLLTSSNYDDSVKKTTGGRNGYGAKLTNIFSTEFVI 177

Query: 607  ETADGKRQRKYKQVFSNNMGTKTEPIISKCKAGENWTRITFKPDLVKFSMSYLEEDVVAL 786
            ETADGKRQRKYKQVFSNNMG + EP I KCK G+NWT+++FKPDL KF+M++LE+DVVAL
Sbjct: 178  ETADGKRQRKYKQVFSNNMGKRNEPTIVKCKEGDNWTKVSFKPDLSKFNMTHLEDDVVAL 237

Query: 787  MKKRVIDVAGCLGKTVKVELNGQLFHFKSFSNYCDLYMKSTSVSTLDP-LPRFEEEVHDR 963
            MKKRV+D+AGCLGKTVKVELNG+    K+F  Y  LY+ S S +  +  LPR EE V+DR
Sbjct: 238  MKKRVVDLAGCLGKTVKVELNGKRVPVKTFGEYVGLYLASASKNRPESSLPRIEEAVNDR 297

Query: 964  WQVCISRSEGQFQQVSFVNGIATVKGGTHVDYVTNKITSHLVSVIXXXXXXXXXFDLKPH 1143
            W+VC+S SEGQFQQVSFVN IAT+KGGTHVDYVTN+I +H++SV+          +LK H
Sbjct: 298  WEVCVSLSEGQFQQVSFVNSIATIKGGTHVDYVTNQIANHVMSVVNKKNKNA---NLKAH 354

Query: 1144 TVKNHLWVFVNALIDNPAFDSQTKETLTLRAASFGSSWDFSSKFLDKVAKSDIMKNIEEW 1323
             VKNHLWVFVNALIDNPAFDSQTKETLTLR +SFGS  + S KFL KVAKS I++ +  W
Sbjct: 355  NVKNHLWVFVNALIDNPAFDSQTKETLTLRQSSFGSKCELSDKFLQKVAKSGIVETLLSW 414

Query: 1324 AEFKQKKDLKKTDGSKDRRIYGLAKLADANEAGGKNSEKCTLILTEGDSAKALAIAGLSV 1503
            A FK  KDLKKTDGSK   + G+ KL DAN+AGG+NS+KCTLILTEGDSAKALA+AGLSV
Sbjct: 415  ATFKLSKDLKKTDGSKKENLRGIPKLEDANDAGGRNSDKCTLILTEGDSAKALAMAGLSV 474

Query: 1504 VGRDHYGVFPLRGKLLNVREASHNQLMQNVEIQHIKQILGLQHGKQYDSVKPLRYGHLMI 1683
            VGRDHYGVFPLRGKLLNVREASH+Q+M N EIQHIKQILGLQ  K YDSVK LRYGHLMI
Sbjct: 475  VGRDHYGVFPLRGKLLNVREASHSQIMDNKEIQHIKQILGLQQNKDYDSVKSLRYGHLMI 534

Query: 1684 MTDQDHDGSHIKGLLINFIHSFWPSLLKVPTFLLEFITPIVKATHRDGKRKESFYTMPQY 1863
            MTDQDHDGSHIKGLLINFIHSFWPSLLKVP+F++EFITPIVKATH++G R+  FYTMP+Y
Sbjct: 535  MTDQDHDGSHIKGLLINFIHSFWPSLLKVPSFMVEFITPIVKATHKNG-RELCFYTMPEY 593

Query: 1864 ETWKQNQGTDVKNWTIKYYKGLGTSTDQEAKEYFEALGRHKKDFVWVDEQDGDAIELAFS 2043
            E+WK++   +   W+IKYYKGLGTST +E K+YF+AL +HKKDF+W DE+DG+AIELAFS
Sbjct: 594  ESWKESLSGNASGWSIKYYKGLGTSTSKEGKQYFQALNKHKKDFIWADEKDGEAIELAFS 653

Query: 2044 KKKIEARKNWLRQFEPGTYLCDLEEHIKYRDFVHKELILFSIADLQRSIPSMVDGLKPGQ 2223
            KKKIEARKNWLRQFEPGT+L   E+ IKY DFV+KELILFS+ADLQRSIPSM+DGLKPGQ
Sbjct: 654  KKKIEARKNWLRQFEPGTFLDQKEKLIKYSDFVNKELILFSMADLQRSIPSMLDGLKPGQ 713

Query: 2224 RKILFCSFKRNFIKEAKVAQFSGYVSEHSAYHHGEQSLASTIIGMAQDYVGSNNINLLLP 2403
            RKILFCSFKRNF+KEAKVAQFSGYVSEHSAYHHGEQSLA TIIGMAQD+VGSNNINLL+P
Sbjct: 714  RKILFCSFKRNFVKEAKVAQFSGYVSEHSAYHHGEQSLAGTIIGMAQDFVGSNNINLLVP 773

Query: 2404 NGQFGTRGQGGKDHASARYIYTQLSSITRFLFPKADDFLLNYLNEDGQSIEPTWYVPTIP 2583
            +GQFGTR  GGKDHAS RYIYT+LS ITRFLFPK DD LL+YLNEDG SIEPTW+VP IP
Sbjct: 774  SGQFGTRNMGGKDHASPRYIYTRLSPITRFLFPKDDDNLLDYLNEDGVSIEPTWFVPIIP 833

Query: 2584 MVLVNGSEGIGTGWSTFIPNYNPLDIIANVRHLLNDEPMEPMHPWYKGFIGSIEKTATKE 2763
             VLVNGSEGIGTGWS++IPNYNP DII NVR LLN E MEPM PWY+GF G+IEKTATKE
Sbjct: 834  TVLVNGSEGIGTGWSSYIPNYNPRDIINNVRRLLNGEMMEPMDPWYRGFKGTIEKTATKE 893

Query: 2764 AGNSYTVSGIIEEVDETSLRITELPIRKWTQDYKEFLES-VSAENDKSKDPFIEGCRDNS 2940
            AG+SYTV GI+EE++ET+LRITELPIR+WTQDY+EFLES V  + DK+K+PFI+  +  S
Sbjct: 894  AGDSYTVHGIMEEINETTLRITELPIRRWTQDYREFLESLVVGDKDKNKEPFIKEFKQYS 953

Query: 2941 GGEIVHFSVYMSPNNLSEAKQEGLMKKFKLTTSISTSNMHLFDSKGVIKKYDTPEQIIEE 3120
                VHF V +S  N+  AKQEGLMKKFKLT++ISTSNMHLFD+KG+IKKYDTPEQI+EE
Sbjct: 954  DDISVHFEVALSEENMIIAKQEGLMKKFKLTSTISTSNMHLFDAKGIIKKYDTPEQILEE 1013

Query: 3121 FFHIRLEFYDKRKKALLANLENDMLKCDNKYRFIRGVVDGSIIVSNRKRADLFLELKEKG 3300
            FF +RL FY+KRKK LL NLE ++LK DNK RFI GVV+G IIV+NRKRA+LF+EL+EKG
Sbjct: 1014 FFPLRLGFYEKRKKFLLDNLEMELLKLDNKVRFILGVVNGEIIVNNRKRAELFIELQEKG 1073

Query: 3301 FTPFPKKKTAAEIAIAGSTDDADESEENNDVAIGKGVSASDYDYLLSLAIGTLTAEKMKE 3480
            FTPFPKK  + E AIAG+++D++E+E+N++    K V ASDY+YLLS+AIG+LT EK++E
Sbjct: 1074 FTPFPKKTKSIEAAIAGASEDSEETEDNSESTGSKEVKASDYEYLLSMAIGSLTREKVQE 1133

Query: 3481 LRDERDKLMQEVEELKRATVKSLWMHDLDALESKFIEELNKSE------KKWAENRQRIL 3642
            L  ERDKL+ EVE LK +T   LW+ DL+ LE + ++EL+K++      +K ++ R    
Sbjct: 1134 LCAERDKLLDEVEGLKSSTPMDLWLKDLEDLERE-LDELDKNDAEADAARKVSQARATSA 1192

Query: 3643 GEAKGTRPVQTKPRKNTKKASNKESVVEQMEV----SDNTVTETDKVGEVXXXXXXXXXX 3810
              AKG+R     PRKNTKKA+N E+V E  E+    S + VT+                 
Sbjct: 1193 AGAKGSRQAPKNPRKNTKKATNLEAVGENSEMPSTNSSSVVTDNAAPVAKPKGRGGAKKA 1252

Query: 3811 XXXXXXXXXXXXXXXXXXXXXXXXLRHRLAAYNFDSSPDRSEDMETEQPQMPTKKKEPNR 3990
                                    L+ RLA YN DSSP+ S   E E PQ+P  KKEP +
Sbjct: 1253 PAATKQNRSAAVLEDEDDDEELLDLKERLARYNLDSSPENSAATENEGPQVPATKKEPTK 1312

Query: 3991 RTAAQKKPLSTVSETXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXTKPPLAGTKKR 4170
            R AA KK + T+ E+                                   KP  A T+KR
Sbjct: 1313 RAAAAKKTVITLLES------SDEESGKDKAGDEDLDIEVEPPKGKKGGKKPSAAATRKR 1366

Query: 4171 GQQANK--QQTQKLITEVLKPAEN---SPEKKVRKMRASPFNKKSSSILGRTISVDXXXX 4335
            G  ANK     QKL+T++LKP+EN   SPEKKVR+MRASPFN+KSS     TIS +    
Sbjct: 1367 G-PANKTIAAGQKLLTDMLKPSENSDISPEKKVRRMRASPFNRKSSI---PTISEE---- 1418

Query: 4336 XXXXXXXXNSVSTLGSVTEDVSQAVAP-KARPQRGTRGNARY 4458
                        +LGS   D    V P +ARPQR  R   +Y
Sbjct: 1419 ------------SLGSNERDEEAPVLPSRARPQRANRQQKKY 1448


>ref|XP_021295966.1| DNA topoisomerase 2 [Herrania umbratica]
          Length = 1475

 Score = 1871 bits (4847), Expect = 0.0
 Identities = 963/1476 (65%), Positives = 1134/1476 (76%), Gaps = 17/1476 (1%)
 Frame = +1

Query: 82   KAPLTTSNNANIPPSETVTAAGGKKTIEQTYQKKTQLEHILLRPDTYIGSIEKHTQTLWV 261
            K PL +SNNAN+  S         KTIE+TYQKKTQLEHILLRPDTYIGSIE+HTQ LWV
Sbjct: 6    KLPLQSSNNANMKAS---------KTIEETYQKKTQLEHILLRPDTYIGSIEQHTQRLWV 56

Query: 262  YENEQMVQKSITFVPGLYKIFDEILVNAADNKQRDPKMDSVKVTIDVESSCISVYNNGDG 441
            YEN++MV + I +VPGLYKIFDEILVNAADNKQRDP MDSVKV ID E + ISVYN+GDG
Sbjct: 57   YENDEMVHRDIKYVPGLYKIFDEILVNAADNKQRDPSMDSVKVVIDEEQNLISVYNSGDG 116

Query: 442  VPVEIHQEEGVYVPELIFGHLLTSSNYDDNEKKTTGGRNGYGAKLTNIFSTEFVIETADG 621
            VPVE+HQEEGVYVPELIFGHLLTSSNYDD  KKTTGGRNGYGAKLTNIFSTEFVIETADG
Sbjct: 117  VPVEVHQEEGVYVPELIFGHLLTSSNYDDTVKKTTGGRNGYGAKLTNIFSTEFVIETADG 176

Query: 622  KRQRKYKQVFSNNMGTKTEPIISKCKAGENWTRITFKPDLVKFSMSYLEEDVVALMKKRV 801
            KRQ+KYKQVFSNNMG K+EP+ISKCK  ENWT++TFKPDL KF+M++LEEDVVALMKKRV
Sbjct: 177  KRQKKYKQVFSNNMGEKSEPVISKCKEAENWTKVTFKPDLAKFNMTHLEEDVVALMKKRV 236

Query: 802  IDVAGCLGKTVKVELNGQLFHFKSFSNYCDLYMKSTSVSTLDPLPRFEEEVHDRWQVCIS 981
             D+AGCLGKTVKVELNG+    KSF +Y  LY+ + S +  +PLPR  E+V++RW+VC+S
Sbjct: 237  FDLAGCLGKTVKVELNGKRVPVKSFLDYVSLYLSAASKTKTEPLPRLLEKVNERWEVCVS 296

Query: 982  RSEGQFQQVSFVNGIATVKGGTHVDYVTNKITSHLVSVIXXXXXXXXXFDLKPHTVKNHL 1161
             S+GQFQQVSFVNGIAT+KGGTHVDYVTN+I++++++++          ++K H VKNHL
Sbjct: 297  LSDGQFQQVSFVNGIATIKGGTHVDYVTNQISNYVMNIVNKKNKNA---NVKAHNVKNHL 353

Query: 1162 WVFVNALIDNPAFDSQTKETLTLRAASFGSSWDFSSKFLDKVAKSDIMKNIEEWAEFKQK 1341
            WVFVNALIDNPAFDSQTKETLTLR +SFGS  + S  FL KVAK  ++ N+  WAEFK  
Sbjct: 354  WVFVNALIDNPAFDSQTKETLTLRQSSFGSKCELSEDFLKKVAKCGVVDNLLSWAEFKHS 413

Query: 1342 KDLKKTDGSKDRRIYGLAKLADANEAGGKNSEKCTLILTEGDSAKALAIAGLSVVGRDHY 1521
            KDLKKTDG+K   I G+ KL DANEAGG+NS+KCTLILTEGDSAKALA+AGL+VVGR+HY
Sbjct: 414  KDLKKTDGAKTGSIRGIPKLDDANEAGGRNSDKCTLILTEGDSAKALAVAGLAVVGRNHY 473

Query: 1522 GVFPLRGKLLNVREASHNQLMQNVEIQHIKQILGLQHGKQYDSVKPLRYGHLMIMTDQDH 1701
            GVFPLRGKLLNVREASH QLM N EIQ++K+ILGLQ GK+Y +VK LRYGHLMIMTDQDH
Sbjct: 474  GVFPLRGKLLNVREASHKQLMDNAEIQNLKRILGLQQGKEYTNVKSLRYGHLMIMTDQDH 533

Query: 1702 DGSHIKGLLINFIHSFWPSLLKVPTFLLEFITPIVKATHRDGKRKESFYTMPQYETWKQN 1881
            DGSHIKGLLINFIHSFWPSLLKVP+F++EFITPIVKATH+  K   SFY+MP+YE+WK+ 
Sbjct: 534  DGSHIKGLLINFIHSFWPSLLKVPSFMVEFITPIVKATHKT-KGVLSFYSMPEYESWKER 592

Query: 1882 QGTDVKNWTIKYYKGLGTSTDQEAKEYFEALGRHKKDFVWVDEQDGDAIELAFSKKKIEA 2061
             G + K W+IKYYKGLGTST +E K+YF+ L +HKK+FVW  +QDG+AIELAFSKKKIEA
Sbjct: 593  LGGNAKGWSIKYYKGLGTSTSKEGKDYFKNLDKHKKEFVWQGDQDGEAIELAFSKKKIEA 652

Query: 2062 RKNWLRQFEPGTYLCDLEEHIKYRDFVHKELILFSIADLQRSIPSMVDGLKPGQRKILFC 2241
            RKNWLRQFEPGT+L   ++ IKY +F++KELILFS+ADLQRSIPSM+DGLKPGQRKILFC
Sbjct: 653  RKNWLRQFEPGTHLDQSQKLIKYSEFINKELILFSMADLQRSIPSMIDGLKPGQRKILFC 712

Query: 2242 SFKRNFIKEAKVAQFSGYVSEHSAYHHGEQSLASTIIGMAQDYVGSNNINLLLPNGQFGT 2421
            SFKRNF+KEAKVAQFSGYVSEHSAYHHGEQSLASTI+GMAQD+VGSNNINLL P GQFGT
Sbjct: 713  SFKRNFVKEAKVAQFSGYVSEHSAYHHGEQSLASTIVGMAQDFVGSNNINLLHPGGQFGT 772

Query: 2422 RGQGGKDHASARYIYTQLSSITRFLFPKADDFLLNYLNEDGQSIEPTWYVPTIPMVLVNG 2601
            R QGGKD ASARYI+T LS ITR+LFPK DD +L+YLNEDGQSIEP WYVP IPMVLVNG
Sbjct: 773  RNQGGKDAASARYIFTNLSPITRYLFPKDDDGVLDYLNEDGQSIEPIWYVPIIPMVLVNG 832

Query: 2602 SEGIGTGWSTFIPNYNPLDIIANVRHLLNDEPMEPMHPWYKGFIGSIEKTATKEAGNSYT 2781
            SEGIGTGWS++IPNYNP DI+ANVR LLNDE MEPMHPWY+GF G+IEKTA+KEAG +YT
Sbjct: 833  SEGIGTGWSSYIPNYNPRDIVANVRRLLNDEQMEPMHPWYRGFKGNIEKTASKEAGVTYT 892

Query: 2782 VSGIIEEVDETSLRITELPIRKWTQDYKEFLESVSAENDKSKDPFIEGCRDNSGGEIVHF 2961
            ++G+IEEVDE +LRITELP+R+WTQDY+EFLES+   N    DPFI+  R  S    V F
Sbjct: 893  ITGVIEEVDEATLRITELPVRRWTQDYREFLESIITGN----DPFIKEFRQYSDDTTVEF 948

Query: 2962 SVYMSPNNLSEAKQEGLMKKFKLTTSISTSNMHLFDSKGVIKKYDTPEQIIEEFFHIRLE 3141
             V ++  N+  AKQEGL+KKFKLTT+ISTSNMHLFDSKG+IKKYDTPEQI+EEFFH+R E
Sbjct: 949  EVILTEENMMMAKQEGLLKKFKLTTTISTSNMHLFDSKGMIKKYDTPEQILEEFFHLRFE 1008

Query: 3142 FYDKRKKALLANLENDMLKCDNKYRFIRGVVDGSIIVSNRKRADLFLELKEKGFTPFPKK 3321
            FY+KRKK LL NLE ++LK +NK RFI GVV G IIV+NRKRADLFLEL+ KGFTPFPKK
Sbjct: 1009 FYEKRKKLLLDNLEMELLKMENKVRFILGVVKGEIIVNNRKRADLFLELQTKGFTPFPKK 1068

Query: 3322 KTAAEIAIAGSTDDADESEENNDVAIGKGVSASDYDYLLSLAIGTLTAEKMKELRDERDK 3501
                E+A+AG+TDD +E+EEN++V+  KGV ASDYDYLLS+AIG+LT EK++EL  +RDK
Sbjct: 1069 AKTVEVAVAGATDDTEETEENSEVS-AKGVQASDYDYLLSMAIGSLTLEKVQELCADRDK 1127

Query: 3502 LMQEVEELKRATVKSLWMHDLDALESKFIEELNKSEKKWAENRQRILGEA--KGTRPVQT 3675
            L QEVE+L++AT KSLW+ DLD LE +  E+   ++ + A    +   EA  +  R    
Sbjct: 1128 LQQEVEDLRKATPKSLWLKDLDNLEIQLDEQDKAAQAEEAAKLVKGRAEAGKRAQRQAPK 1187

Query: 3676 KPRKNTKKASNKESVVEQMEVSDNTVTETDKVGEVXXXXXXXXXXXXXXXXXXXXXXXXX 3855
             PRK  KK  N E+V E  ++S ++  ET+                              
Sbjct: 1188 IPRKINKKEKNAETVTETSDISSSSAMETENA-----PAAVKPKGRGGSRKAKKDDSDDD 1242

Query: 3856 XXXXXXXXXLRHRLAAYNFDSSPDRSEDMETEQPQMPTKKKEPNRRTAA-QKKPLSTVSE 4032
                     LR RLA YN DSSPD S  METE P +P  KKEP++R AA +KKP S++SE
Sbjct: 1243 DDEDFGIPDLRERLAKYNLDSSPDHSAAMETEVPLVPAGKKEPSKRAAATRKKPASSLSE 1302

Query: 4033 ---------TXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXTKPPLAGTKKRGQQAN 4185
                                                         KPP A  KKRG  A+
Sbjct: 1303 ISESIGEIDINDEDLDVVEVEVAAAAAPAGKKGGRKPAANSKAAAKPP-AAAKKRGPAAS 1361

Query: 4186 --KQQTQKLITEVLKPAEN---SPEKKVRKMRASPFNKKSSSILGRTISVDXXXXXXXXX 4350
              K Q QKL+TE+LKPAE+   SPEKKVRKMRASPFNKKS S+LGR   V          
Sbjct: 1362 GKKSQQQKLLTEMLKPAEDSGISPEKKVRKMRASPFNKKSGSVLGR---VGKEQESTTDS 1418

Query: 4351 XXXNSVSTLGSVTEDVSQAVAPKARPQRGTRGNARY 4458
                  S++ + TE+V++ V  + RPQR  R    Y
Sbjct: 1419 EETFGSSSMSADTEEVTEIVPARPRPQRTNRKQTTY 1454