BLASTX 2.2.26 [Sep-21-2011]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= Rehmannia29_contig00022985
         (2245 letters)

Database: All non-redundant GenBank CDS
translations+PDB+SwissProt+PIR+PRF excluding environmental samples
from WGS projects 
           149,584,005 sequences; 54,822,741,787 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

ref|XP_012849677.1| PREDICTED: DNA topoisomerase 2 [Erythranthe ...  1150   0.0  
ref|XP_011087923.1| DNA topoisomerase 2 isoform X2 [Sesamum indi...  1142   0.0  
ref|XP_011087914.1| DNA topoisomerase 2 isoform X1 [Sesamum indi...  1142   0.0  
dbj|BAE06274.1| topoisomerase II [Scutellaria baicalensis]           1068   0.0  
gb|KZV36276.1| DNA topoisomerase 2 [Dorcoceras hygrometricum]        1065   0.0  
gb|EPS67102.1| hypothetical protein M569_07672 [Genlisea aurea]       965   0.0  
gb|EPS73185.1| hypothetical protein M569_01571, partial [Genlise...   962   0.0  
ref|XP_002274267.1| PREDICTED: DNA topoisomerase 2 [Vitis vinifera]   958   0.0  
ref|XP_010241214.1| PREDICTED: DNA topoisomerase 2-like isoform ...   950   0.0  
emb|CDP07797.1| unnamed protein product [Coffea canephora]            947   0.0  
ref|XP_010241213.1| PREDICTED: DNA topoisomerase 2-like isoform ...   946   0.0  
ref|XP_022896608.1| DNA topoisomerase 2 [Olea europaea var. sylv...   937   0.0  
gb|OVA19386.1| DNA topoisomerase II [Macleaya cordata]                935   0.0  
ref|XP_015881654.1| PREDICTED: DNA topoisomerase 2 isoform X2 [Z...   931   0.0  
ref|XP_015881653.1| PREDICTED: DNA topoisomerase 2 isoform X1 [Z...   926   0.0  
gb|EOY18138.1| DNA topoisomerase 2 isoform 2 [Theobroma cacao]        924   0.0  
gb|EOY18137.1| DNA topoisomerase 2 isoform 1 [Theobroma cacao]        924   0.0  
ref|XP_007009327.2| PREDICTED: DNA topoisomerase 2 [Theobroma ca...   921   0.0  
ref|XP_008231458.1| PREDICTED: DNA topoisomerase 2 isoform X2 [P...   915   0.0  
ref|XP_010023678.1| PREDICTED: DNA topoisomerase 2 [Eucalyptus g...   916   0.0  

>ref|XP_012849677.1| PREDICTED: DNA topoisomerase 2 [Erythranthe guttata]
 gb|EYU27037.1| hypothetical protein MIMGU_mgv1a000169mg [Erythranthe guttata]
          Length = 1503

 Score = 1150 bits (2976), Expect = 0.0
 Identities = 569/723 (78%), Positives = 630/723 (87%), Gaps = 2/723 (0%)
 Frame = -3

Query: 2240 WKQNQGTDVKNWTIKYYKGLGTSTDQEAKEYFEALGRHKKDFVWVDEQDGDAIELAFSKK 2061
            WK++ G+D KNWTIKYYKGLGTSTD+E KEYFE LG+HKKDFVWVDEQDGDAIELAFSKK
Sbjct: 606  WKESIGSDAKNWTIKYYKGLGTSTDKEGKEYFEDLGKHKKDFVWVDEQDGDAIELAFSKK 665

Query: 2060 KIEARKNWLRQFEPGTYLCDLEEHIKYRDFVHKELILFSIADLQRSIPSMVDGLKPGQRK 1881
            KIEARK+WLRQFEPGTYL D + HIKYRDFVHKELILFSIADLQRSIPSMVDGLKPGQRK
Sbjct: 666  KIEARKSWLRQFEPGTYLDDRDSHIKYRDFVHKELILFSIADLQRSIPSMVDGLKPGQRK 725

Query: 1880 ILFCSFKRNFIKEAKVAQFSGYVSEHSAYHHGEQSLASTIIGMAQDYVGSNNINLLLPNG 1701
            IL+CSFKRNF+KEAKVAQFSGYVSEHSAYHHGEQSLASTIIGMAQDYVGSNNINLLLPNG
Sbjct: 726  ILYCSFKRNFVKEAKVAQFSGYVSEHSAYHHGEQSLASTIIGMAQDYVGSNNINLLLPNG 785

Query: 1700 QFGTRGQGGKDHASARYIYTQLSSITRFLFPKADDFLLNYLNEDGQSIEPTWYVPTIPMV 1521
            QFGTRGQGGKDHASARY+YTQLS +TRFLFPKADD LL+YLNEDGQ IEPTWYVP IP V
Sbjct: 786  QFGTRGQGGKDHASARYVYTQLSPVTRFLFPKADDILLDYLNEDGQMIEPTWYVPIIPTV 845

Query: 1520 LVNGSEGIGTGWSTFIPNYNPLDIIANVRHLLNDEPMEPMHPWYKGFIGLIEKTATKEAG 1341
            LVNGSEGIGTGWS+F+PNYNPLDIIANVRHLLN EPME MHPWYKGF G IEKTATKEAG
Sbjct: 846  LVNGSEGIGTGWSSFVPNYNPLDIIANVRHLLNGEPMEAMHPWYKGFKGTIEKTATKEAG 905

Query: 1340 NSYTVSGIIEEVDETSLRITELPIRKWTQDYKEFLESVSAENDKSKDPFIEGCRDNSGGE 1161
             SYTV+GIIEEVDET+L ITELPIR+WTQDYKEFLES+SAENDKSKDPFIEGCRDNSGGE
Sbjct: 906  FSYTVTGIIEEVDETTLTITELPIRRWTQDYKEFLESISAENDKSKDPFIEGCRDNSGGE 965

Query: 1160 IVHFSVYMSPNNLSEAKQEGLMKKFKLTTSISTSNMHLFDSKGVIKKYDTPEQIIEEFFH 981
            I+HF+VY+S  NL  AKQEGL+KKFKLTT++STSNMHLFDSKGVIKKYD+PEQI+EEFF+
Sbjct: 966  IIHFAVYLSETNLLVAKQEGLLKKFKLTTTMSTSNMHLFDSKGVIKKYDSPEQILEEFFY 1025

Query: 980  IRLEFYDKRKKALLANLENDMLKCDNKYRFIRGVVDGSIIVSNRKRADLFLELKEKGFTP 801
            IRLEFY+KRKKALLANLE DMLKCDNKYRFIRGVV+G+I+VSNRK+ADLFLELK KGFTP
Sbjct: 1026 IRLEFYEKRKKALLANLELDMLKCDNKYRFIRGVVEGTIVVSNRKKADLFLELKAKGFTP 1085

Query: 800  FPKKKTAAEIAIAGSTDDADESEENNDVAIGKGVSASDYDYLLSLAIGTLTAEKMKELRD 621
            FPKKK   E+A+AG+TDD +E+E+N +V I KGVSASDYDYLLSLAIGTLTAEK++ELRD
Sbjct: 1086 FPKKKNTPEVAVAGATDDTEETEDNTEVEIAKGVSASDYDYLLSLAIGTLTAEKLQELRD 1145

Query: 620  ERDKLMQEVEELKRATVKSLWMHDLDALESKFIEELNKSEKKWAENRQRIL-GEAKGTRP 444
            ER++L QEVE+LK++TVKSLW  DLDALE+K IE+L  SEKKW E+RQRI  GE K  RP
Sbjct: 1146 ERERLTQEVEDLKKSTVKSLWTKDLDALEAKIIEDLKNSEKKWEEDRQRIQGGETKIARP 1205

Query: 443  VQTKPRKNTKKA-SNKESVVEQMEVSDNTVTETDKVGEVXXXXXXXXXXXXXXXXXXXXX 267
            +   PRKNTKKA + KES  E M+VSDNTVTETDKV E+                     
Sbjct: 1206 LAKNPRKNTKKATTKKESTAEHMDVSDNTVTETDKVAEI-KKPRGKAAAAKKKAPVAKVV 1264

Query: 266  XXXXXXXXXXXXDLRHRLAAYNFDSSPDRSEDMETEQPQMPTKKKEPNRRTAAQKKPLST 87
                        +LR R+AAYNFDSSPDR+EDMETE PQ+ TKKKEP +R A +KK +S 
Sbjct: 1265 AEADEDDDDGVAELRQRIAAYNFDSSPDRAEDMETELPQLQTKKKEPTKRAAPRKKQVSI 1324

Query: 86   VSE 78
            VS+
Sbjct: 1325 VSD 1327


>ref|XP_011087923.1| DNA topoisomerase 2 isoform X2 [Sesamum indicum]
          Length = 1483

 Score = 1142 bits (2954), Expect = 0.0
 Identities = 576/723 (79%), Positives = 627/723 (86%), Gaps = 1/723 (0%)
 Frame = -3

Query: 2240 WKQNQGTDVKNWTIKYYKGLGTSTDQEAKEYFEALGRHKKDFVWVDEQDGDAIELAFSKK 2061
            WK+  G D KNW+IKYYKGLGTSTDQE KEYFE LG+HKKDFVWVDEQDG+AIELAFSKK
Sbjct: 604  WKEKLGADAKNWSIKYYKGLGTSTDQEGKEYFEDLGKHKKDFVWVDEQDGEAIELAFSKK 663

Query: 2060 KIEARKNWLRQFEPGTYLCDLEEHIKYRDFVHKELILFSIADLQRSIPSMVDGLKPGQRK 1881
            KIEARKNW+RQFEPGTYL + ++HIKYRDFVHKELILFSIADLQRSIPSMVDGLKPGQRK
Sbjct: 664  KIEARKNWIRQFEPGTYLSEQDKHIKYRDFVHKELILFSIADLQRSIPSMVDGLKPGQRK 723

Query: 1880 ILFCSFKRNFIKEAKVAQFSGYVSEHSAYHHGEQSLASTIIGMAQDYVGSNNINLLLPNG 1701
            ILFCSFKRNFIKEAKVAQFSGYVSEHSAYHHGEQSLASTIIGMAQDYVGSNNINLLLPNG
Sbjct: 724  ILFCSFKRNFIKEAKVAQFSGYVSEHSAYHHGEQSLASTIIGMAQDYVGSNNINLLLPNG 783

Query: 1700 QFGTRGQGGKDHASARYIYTQLSSITRFLFPKADDFLLNYLNEDGQSIEPTWYVPTIPMV 1521
            QFGTRGQGGKDHASARYI+TQLS ITR+LFPKADD LLNYLNEDGQSIEP+WYVP IPMV
Sbjct: 784  QFGTRGQGGKDHASARYIFTQLSPITRYLFPKADDILLNYLNEDGQSIEPSWYVPIIPMV 843

Query: 1520 LVNGSEGIGTGWSTFIPNYNPLDIIANVRHLLNDEPMEPMHPWYKGFIGLIEKTATKEAG 1341
            LVNGSEGIGTGWS+FIPNYNPLDIIAN+RHLLNDEPM PMHPWYKGF G IEKTATKEAG
Sbjct: 844  LVNGSEGIGTGWSSFIPNYNPLDIIANLRHLLNDEPMVPMHPWYKGFRGSIEKTATKEAG 903

Query: 1340 NSYTVSGIIEEVDETSLRITELPIRKWTQDYKEFLESVSAENDKSKDPFIEGCRDNSGGE 1161
            NSYTVSGIIEE+DE +L ITELP+RKWTQDYKEFLES+SAEN+KSKDPFIEGCRDNSGGE
Sbjct: 904  NSYTVSGIIEELDERTLSITELPVRKWTQDYKEFLESISAENEKSKDPFIEGCRDNSGGE 963

Query: 1160 IVHFSVYMSPNNLSEAKQEGLMKKFKLTTSISTSNMHLFDSKGVIKKYDTPEQIIEEFFH 981
            IV+F VY+S  NL  AKQEGL+KKFKLTTSISTSNMHLFD+KGVIKKYDTPEQI+EEFFH
Sbjct: 964  IVNFLVYLSAENLLIAKQEGLLKKFKLTTSISTSNMHLFDAKGVIKKYDTPEQILEEFFH 1023

Query: 980  IRLEFYDKRKKALLANLENDMLKCDNKYRFIRGVVDGSIIVSNRKRADLFLELKEKGFTP 801
            IRLEFY+KRK+ LLANLENDMLKC+NK RFI+ VV+ SIIVSNR+RADLFLELKEKGFTP
Sbjct: 1024 IRLEFYEKRKRVLLANLENDMLKCENKCRFIQCVVESSIIVSNRRRADLFLELKEKGFTP 1083

Query: 800  FPKKKTAAEIAIAGSTDDADESEENNDVAIGKGVSASDYDYLLSLAIGTLTAEKMKELRD 621
            FPKKKTAAE+AIAGS D+A+E+EEN         SASDYDYLLSLAIGTLTAEK++ELR 
Sbjct: 1084 FPKKKTAAEVAIAGSLDEAEETEEN--------TSASDYDYLLSLAIGTLTAEKIQELRA 1135

Query: 620  ERDKLMQEVEELKRATVKSLWMHDLDALESKFIEELNKSEKKWAENRQRILGEAKGTRPV 441
            ERDKLMQEVE LKRATVKSLWM+DLDALESKFIEE NKSEKKW + R++I G    +RPV
Sbjct: 1136 ERDKLMQEVENLKRATVKSLWMNDLDALESKFIEEQNKSEKKWEKEREKINGTVNISRPV 1195

Query: 440  QTKPRKNTKKASNKESVVEQMEVSDNTVTETDKVGEVXXXXXXXXXXXXXXXXXXXXXXX 261
            Q  PRKN KKA+NKES   QMEVS +TV E    G++                       
Sbjct: 1196 QKNPRKNNKKATNKES---QMEVSGDTVPEAGNAGDI--KKPKGRTAAKKKAPAEKVTSV 1250

Query: 260  XXXXXXXXXXDLRHRLAAYNFDSSPDRSEDMETEQ-PQMPTKKKEPNRRTAAQKKPLSTV 84
                      DLRHRLAAYNFDSSPDR ++METE+  Q+ TKKKEP+R+ AAQKKPL TV
Sbjct: 1251 ADENDDEEISDLRHRLAAYNFDSSPDRPQEMETEEVSQLQTKKKEPSRKAAAQKKPLPTV 1310

Query: 83   SET 75
            SE+
Sbjct: 1311 SES 1313


>ref|XP_011087914.1| DNA topoisomerase 2 isoform X1 [Sesamum indicum]
          Length = 1484

 Score = 1142 bits (2954), Expect = 0.0
 Identities = 576/723 (79%), Positives = 627/723 (86%), Gaps = 1/723 (0%)
 Frame = -3

Query: 2240 WKQNQGTDVKNWTIKYYKGLGTSTDQEAKEYFEALGRHKKDFVWVDEQDGDAIELAFSKK 2061
            WK+  G D KNW+IKYYKGLGTSTDQE KEYFE LG+HKKDFVWVDEQDG+AIELAFSKK
Sbjct: 604  WKEKLGADAKNWSIKYYKGLGTSTDQEGKEYFEDLGKHKKDFVWVDEQDGEAIELAFSKK 663

Query: 2060 KIEARKNWLRQFEPGTYLCDLEEHIKYRDFVHKELILFSIADLQRSIPSMVDGLKPGQRK 1881
            KIEARKNW+RQFEPGTYL + ++HIKYRDFVHKELILFSIADLQRSIPSMVDGLKPGQRK
Sbjct: 664  KIEARKNWIRQFEPGTYLSEQDKHIKYRDFVHKELILFSIADLQRSIPSMVDGLKPGQRK 723

Query: 1880 ILFCSFKRNFIKEAKVAQFSGYVSEHSAYHHGEQSLASTIIGMAQDYVGSNNINLLLPNG 1701
            ILFCSFKRNFIKEAKVAQFSGYVSEHSAYHHGEQSLASTIIGMAQDYVGSNNINLLLPNG
Sbjct: 724  ILFCSFKRNFIKEAKVAQFSGYVSEHSAYHHGEQSLASTIIGMAQDYVGSNNINLLLPNG 783

Query: 1700 QFGTRGQGGKDHASARYIYTQLSSITRFLFPKADDFLLNYLNEDGQSIEPTWYVPTIPMV 1521
            QFGTRGQGGKDHASARYI+TQLS ITR+LFPKADD LLNYLNEDGQSIEP+WYVP IPMV
Sbjct: 784  QFGTRGQGGKDHASARYIFTQLSPITRYLFPKADDILLNYLNEDGQSIEPSWYVPIIPMV 843

Query: 1520 LVNGSEGIGTGWSTFIPNYNPLDIIANVRHLLNDEPMEPMHPWYKGFIGLIEKTATKEAG 1341
            LVNGSEGIGTGWS+FIPNYNPLDIIAN+RHLLNDEPM PMHPWYKGF G IEKTATKEAG
Sbjct: 844  LVNGSEGIGTGWSSFIPNYNPLDIIANLRHLLNDEPMVPMHPWYKGFRGSIEKTATKEAG 903

Query: 1340 NSYTVSGIIEEVDETSLRITELPIRKWTQDYKEFLESVSAENDKSKDPFIEGCRDNSGGE 1161
            NSYTVSGIIEE+DE +L ITELP+RKWTQDYKEFLES+SAEN+KSKDPFIEGCRDNSGGE
Sbjct: 904  NSYTVSGIIEELDERTLSITELPVRKWTQDYKEFLESISAENEKSKDPFIEGCRDNSGGE 963

Query: 1160 IVHFSVYMSPNNLSEAKQEGLMKKFKLTTSISTSNMHLFDSKGVIKKYDTPEQIIEEFFH 981
            IV+F VY+S  NL  AKQEGL+KKFKLTTSISTSNMHLFD+KGVIKKYDTPEQI+EEFFH
Sbjct: 964  IVNFLVYLSAENLLIAKQEGLLKKFKLTTSISTSNMHLFDAKGVIKKYDTPEQILEEFFH 1023

Query: 980  IRLEFYDKRKKALLANLENDMLKCDNKYRFIRGVVDGSIIVSNRKRADLFLELKEKGFTP 801
            IRLEFY+KRK+ LLANLENDMLKC+NK RFI+ VV+ SIIVSNR+RADLFLELKEKGFTP
Sbjct: 1024 IRLEFYEKRKRVLLANLENDMLKCENKCRFIQCVVESSIIVSNRRRADLFLELKEKGFTP 1083

Query: 800  FPKKKTAAEIAIAGSTDDADESEENNDVAIGKGVSASDYDYLLSLAIGTLTAEKMKELRD 621
            FPKKKTAAE+AIAGS D+A+E+EEN         SASDYDYLLSLAIGTLTAEK++ELR 
Sbjct: 1084 FPKKKTAAEVAIAGSLDEAEETEEN--------TSASDYDYLLSLAIGTLTAEKIQELRA 1135

Query: 620  ERDKLMQEVEELKRATVKSLWMHDLDALESKFIEELNKSEKKWAENRQRILGEAKGTRPV 441
            ERDKLMQEVE LKRATVKSLWM+DLDALESKFIEE NKSEKKW + R++I G    +RPV
Sbjct: 1136 ERDKLMQEVENLKRATVKSLWMNDLDALESKFIEEQNKSEKKWEKEREKINGTVNISRPV 1195

Query: 440  QTKPRKNTKKASNKESVVEQMEVSDNTVTETDKVGEVXXXXXXXXXXXXXXXXXXXXXXX 261
            Q  PRKN KKA+NKES   QMEVS +TV E    G++                       
Sbjct: 1196 QKNPRKNNKKATNKES---QMEVSGDTVPEAGNAGDI-KKPKGRTAAKKKAPAEKQVTSV 1251

Query: 260  XXXXXXXXXXDLRHRLAAYNFDSSPDRSEDMETEQ-PQMPTKKKEPNRRTAAQKKPLSTV 84
                      DLRHRLAAYNFDSSPDR ++METE+  Q+ TKKKEP+R+ AAQKKPL TV
Sbjct: 1252 ADENDDEEISDLRHRLAAYNFDSSPDRPQEMETEEVSQLQTKKKEPSRKAAAQKKPLPTV 1311

Query: 83   SET 75
            SE+
Sbjct: 1312 SES 1314


>dbj|BAE06274.1| topoisomerase II [Scutellaria baicalensis]
          Length = 1469

 Score = 1068 bits (2761), Expect = 0.0
 Identities = 538/722 (74%), Positives = 598/722 (82%)
 Frame = -3

Query: 2240 WKQNQGTDVKNWTIKYYKGLGTSTDQEAKEYFEALGRHKKDFVWVDEQDGDAIELAFSKK 2061
            WK+ QGT+ KNWT+KYYKGLGTSTDQEA EYF  LG+H+KDFV+VD +D DAIELAFSKK
Sbjct: 601  WKEAQGTEAKNWTVKYYKGLGTSTDQEAMEYFSDLGKHEKDFVYVDGEDDDAIELAFSKK 660

Query: 2060 KIEARKNWLRQFEPGTYLCDLEEHIKYRDFVHKELILFSIADLQRSIPSMVDGLKPGQRK 1881
            KIEARK WLRQFEPGT+L D + HIKYRDFVHKELILFSIAD+QRSIPSMVDGLKPGQRK
Sbjct: 661  KIEARKGWLRQFEPGTFLDDRDSHIKYRDFVHKELILFSIADVQRSIPSMVDGLKPGQRK 720

Query: 1880 ILFCSFKRNFIKEAKVAQFSGYVSEHSAYHHGEQSLASTIIGMAQDYVGSNNINLLLPNG 1701
            ILFCSFKRNF++EAKVAQFSGYVSEHSAYHHGEQSLA TIIGMAQDYVGSNNINLLLP G
Sbjct: 721  ILFCSFKRNFVREAKVAQFSGYVSEHSAYHHGEQSLAGTIIGMAQDYVGSNNINLLLPIG 780

Query: 1700 QFGTRGQGGKDHASARYIYTQLSSITRFLFPKADDFLLNYLNEDGQSIEPTWYVPTIPMV 1521
            QFGTRGQGGKDHASARY++TQLS +TRFLFPKADD LL+YLNEDGQSIEPTWYVP IPMV
Sbjct: 781  QFGTRGQGGKDHASARYVFTQLSPVTRFLFPKADDILLDYLNEDGQSIEPTWYVPIIPMV 840

Query: 1520 LVNGSEGIGTGWSTFIPNYNPLDIIANVRHLLNDEPMEPMHPWYKGFIGLIEKTATKEAG 1341
            LVNGSEGIGTGWS+++PNYNP+DIIAN+RHLLNDE  EPMHPWYKGF+G +EKTATKEAG
Sbjct: 841  LVNGSEGIGTGWSSYVPNYNPVDIIANIRHLLNDEATEPMHPWYKGFLGSVEKTATKEAG 900

Query: 1340 NSYTVSGIIEEVDETSLRITELPIRKWTQDYKEFLESVSAENDKSKDPFIEGCRDNSGGE 1161
             SYTVSGIIEEVD+T+L I ELPIR+WTQDYKEFLESVSAENDKSKDPFIEGCRD SG E
Sbjct: 901  ASYTVSGIIEEVDDTTLCIKELPIRRWTQDYKEFLESVSAENDKSKDPFIEGCRDYSGSE 960

Query: 1160 IVHFSVYMSPNNLSEAKQEGLMKKFKLTTSISTSNMHLFDSKGVIKKYDTPEQIIEEFFH 981
            +V+F V M P  L  AK+EGL+KKFKLTTSIST NMHLFDSKGVIKKYDTPEQI+EEFF+
Sbjct: 961  LVNFLVGMKPEKLEAAKREGLLKKFKLTTSISTCNMHLFDSKGVIKKYDTPEQILEEFFY 1020

Query: 980  IRLEFYDKRKKALLANLENDMLKCDNKYRFIRGVVDGSIIVSNRKRADLFLELKEKGFTP 801
            IRLE Y+KRKK LL  LE+DMLKCDNKYRFIR VV+GSIIVSNRKR D+F ELKEKGFTP
Sbjct: 1021 IRLELYEKRKKVLLDILEHDMLKCDNKYRFIRCVVEGSIIVSNRKRTDVFRELKEKGFTP 1080

Query: 800  FPKKKTAAEIAIAGSTDDADESEENNDVAIGKGVSASDYDYLLSLAIGTLTAEKMKELRD 621
            FPKKK  AE+AIAG+TDD +E+EEN++V I  GVS+SDYDYLLSLAIGTLT EKM+ELR 
Sbjct: 1081 FPKKKNRAEVAIAGATDDGEETEENSEVPIAPGVSSSDYDYLLSLAIGTLTTEKMQELRA 1140

Query: 620  ERDKLMQEVEELKRATVKSLWMHDLDALESKFIEELNKSEKKWAENRQRILGEAKGTRPV 441
            ERDKLMQEVEELK++T +SLW  DLDALE K  EE    E+ W +N+++I G+      +
Sbjct: 1141 ERDKLMQEVEELKQSTARSLWNKDLDALEDKLAEEQKIYEETWEKNKRKIHGKTDTLEII 1200

Query: 440  QTKPRKNTKKASNKESVVEQMEVSDNTVTETDKVGEVXXXXXXXXXXXXXXXXXXXXXXX 261
            Q  PRKN KK + KES VE ME+S+NT TETD V                          
Sbjct: 1201 QKNPRKN-KKTTKKESAVE-MEISENTTTETD-VKIKKPRGKAAAKKKEPAAKVVTAAPV 1257

Query: 260  XXXXXXXXXXDLRHRLAAYNFDSSPDRSEDMETEQPQMPTKKKEPNRRTAAQKKPLSTVS 81
                      DLR R+AAYNFDSSPD SEDM TE   + TK K+P RR AAQKK LS  S
Sbjct: 1258 EEQEDDDGIADLRQRIAAYNFDSSPDHSEDMATEVAPVQTKNKQPARRGAAQKKTLSAAS 1317

Query: 80   ET 75
            ET
Sbjct: 1318 ET 1319


>gb|KZV36276.1| DNA topoisomerase 2 [Dorcoceras hygrometricum]
          Length = 1455

 Score = 1065 bits (2753), Expect = 0.0
 Identities = 539/724 (74%), Positives = 608/724 (83%), Gaps = 1/724 (0%)
 Frame = -3

Query: 2243 TWKQNQGTDVKNWTIKYYKGLGTSTDQEAKEYFEALGRHKKDFVWVDEQDGDAIELAFSK 2064
            +WK++ G + +NW+IKYYKGLGTST++EAKEYF  L  HKKDF+WVDEQDG+AIELAFSK
Sbjct: 572  SWKESLGENARNWSIKYYKGLGTSTNEEAKEYFGDLRMHKKDFLWVDEQDGEAIELAFSK 631

Query: 2063 KKIEARKNWLRQFEPGTYLCDLEEHIKYRDFVHKELILFSIADLQRSIPSMVDGLKPGQR 1884
            KKIEARK+WLRQFEPGTYL   E+ IKYRDFVHKELILFS+ADLQRSIPSMVDGLKPGQR
Sbjct: 632  KKIEARKSWLRQFEPGTYLDQREKLIKYRDFVHKELILFSMADLQRSIPSMVDGLKPGQR 691

Query: 1883 KILFCSFKRNFIKEAKVAQFSGYVSEHSAYHHGEQSLASTIIGMAQDYVGSNNINLLLPN 1704
            KILFCSFKRNFIKEAKV+QFSGYVSEHSAYHHGEQSLASTIIGMAQDYVGSNNINLL PN
Sbjct: 692  KILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDYVGSNNINLLKPN 751

Query: 1703 GQFGTRGQGGKDHASARYIYTQLSSITRFLFPKADDFLLNYLNEDGQSIEPTWYVPTIPM 1524
            GQFGTRGQGGKDHASARYI+TQLS +TRF+FPKADD LLNYLNEDGQ IEP+WYVP IPM
Sbjct: 752  GQFGTRGQGGKDHASARYIFTQLSPVTRFMFPKADDILLNYLNEDGQRIEPSWYVPIIPM 811

Query: 1523 VLVNGSEGIGTGWSTFIPNYNPLDIIANVRHLLNDEPMEPMHPWYKGFIGLIEKTATKEA 1344
            VLVNGSEGIGTGWS+F+PNYNP DIIANVRHLLNDE M+ MHPWY+GF G IEKTATKEA
Sbjct: 812  VLVNGSEGIGTGWSSFVPNYNPKDIIANVRHLLNDEKMDAMHPWYRGFRGTIEKTATKEA 871

Query: 1343 GN-SYTVSGIIEEVDETSLRITELPIRKWTQDYKEFLESVSAENDKSKDPFIEGCRDNSG 1167
            G  SYT+SGIIEEVD+ +LRITELPIRKWTQDYKEFLESV+AEN+KSKDPFIEGC D+S 
Sbjct: 872  GGVSYTISGIIEEVDDATLRITELPIRKWTQDYKEFLESVAAENEKSKDPFIEGCSDHST 931

Query: 1166 GEIVHFSVYMSPNNLSEAKQEGLMKKFKLTTSISTSNMHLFDSKGVIKKYDTPEQIIEEF 987
            G+IVHF V MS +NL +A+QEGL+KKFKLTTSISTSNMHLFDS G+IKKYDTPEQI+EEF
Sbjct: 932  GDIVHFLVCMSQDNLLQARQEGLLKKFKLTTSISTSNMHLFDSNGLIKKYDTPEQILEEF 991

Query: 986  FHIRLEFYDKRKKALLANLENDMLKCDNKYRFIRGVVDGSIIVSNRKRADLFLELKEKGF 807
            FHIRL+FY+KRKKALLANLEND+LKC+NKY+FIR VV+GSIIVSNRKRADLF ELKEKGF
Sbjct: 992  FHIRLDFYEKRKKALLANLENDLLKCENKYKFIRCVVEGSIIVSNRKRADLFRELKEKGF 1051

Query: 806  TPFPKKKTAAEIAIAGSTDDADESEENNDVAIGKGVSASDYDYLLSLAIGTLTAEKMKEL 627
            TPFPKKK++A++ IAGSTDDA+++ EN+  A G G S SDYDYLLS+AIGTLT EK++EL
Sbjct: 1052 TPFPKKKSSADVFIAGSTDDAEDTGENSPGATGSGDSTSDYDYLLSMAIGTLTLEKLQEL 1111

Query: 626  RDERDKLMQEVEELKRATVKSLWMHDLDALESKFIEELNKSEKKWAENRQRILGEAKGTR 447
            R ERDKL+QEVEELK +T+KSLW+ DLDALE K ++EL +SE+K    R++ILG+AK TR
Sbjct: 1112 RAERDKLLQEVEELKSSTIKSLWLSDLDALEGK-LDELEQSEEKIEVERKKILGKAKITR 1170

Query: 446  PVQTKPRKNTKKASNKESVVEQMEVSDNTVTETDKVGEVXXXXXXXXXXXXXXXXXXXXX 267
            PV   PRKN KK SNKES  E   +S N V ETD + E                      
Sbjct: 1171 PVLKNPRKNNKKTSNKES-AEPNGISVNPVPETDNIAE--NKKVKGKAPAKKKAPARKAA 1227

Query: 266  XXXXXXXXXXXXDLRHRLAAYNFDSSPDRSEDMETEQPQMPTKKKEPNRRTAAQKKPLST 87
                         LR RLA+YN DSSPD  EDMETE   +P K KEP++R AAQ K LS 
Sbjct: 1228 DSDDDDEYDGIAGLRQRLASYNLDSSPDHIEDMETE---VPKKNKEPSKRVAAQTKKLSA 1284

Query: 86   VSET 75
            VSET
Sbjct: 1285 VSET 1288


>gb|EPS67102.1| hypothetical protein M569_07672 [Genlisea aurea]
          Length = 1440

 Score =  965 bits (2495), Expect = 0.0
 Identities = 480/632 (75%), Positives = 539/632 (85%), Gaps = 3/632 (0%)
 Frame = -3

Query: 2240 WKQNQGTDVKNWTIKYYKGLGTSTDQEAKEYFEALGRHKKDFVWVDEQDGDAIELAFSKK 2061
            WKQN G D +NW+IKYYK   + TD E KEYFE L +HKKDFVWVDE+DGDAIELAFSKK
Sbjct: 602  WKQNLGPDSRNWSIKYYKA--SCTDAEGKEYFEDLSKHKKDFVWVDEEDGDAIELAFSKK 659

Query: 2060 KIEARKNWLRQFEPGTYLCDLEEHIKYRDFVHKELILFSIADLQRSIPSMVDGLKPGQRK 1881
            KIEARKNWLRQFEPGT+L   E+HIKYRDFVHKELILFS+ADLQRSIPSMVDGLKPGQRK
Sbjct: 660  KIEARKNWLRQFEPGTFLSQKEKHIKYRDFVHKELILFSVADLQRSIPSMVDGLKPGQRK 719

Query: 1880 ILFCSFKRNFIKEAKVAQFSGYVSEHSAYHHGEQSLASTIIGMAQDYVGSNNINLLLPNG 1701
            ILFCSFKRNF+KEAKVAQFSGYVSEHSAYHHGEQSLASTIIGMAQD+VGSNNINLLLPNG
Sbjct: 720  ILFCSFKRNFVKEAKVAQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNG 779

Query: 1700 QFGTRGQGGKDHASARYIYTQLSSITRFLFPKADDFLLNYLNEDGQSIEPTWYVPTIPMV 1521
            QFGTR QGGKDHASARYIYTQLS  TR+LFPKADD LL+YLNEDGQSIEP WY+P IPMV
Sbjct: 780  QFGTRDQGGKDHASARYIYTQLSPATRYLFPKADDVLLDYLNEDGQSIEPIWYMPIIPMV 839

Query: 1520 LVNGSEGIGTGWSTFIPNYNPLDIIANVRHLLNDEPMEPMHPWYKGFIGLIEKTATKEAG 1341
            LVNGSEGIGTGWSTFIPNYNP DIIANVRHLLNDE M+ M PWY+GF G IEK  TKEAG
Sbjct: 840  LVNGSEGIGTGWSTFIPNYNPRDIIANVRHLLNDEMMDSMQPWYRGFRGSIEKNTTKEAG 899

Query: 1340 NSYTVSGIIEEVDETSLRITELPIRKWTQDYKEFLESVSAENDKSKDPFIEGCRDNSGGE 1161
              Y VSGIIEE+DET+L++TELPIRKWTQDYKEFLESVS+ENDKSKDPFIEGC D S   
Sbjct: 900  TGYNVSGIIEEIDETTLKVTELPIRKWTQDYKEFLESVSSENDKSKDPFIEGCSDYSSPH 959

Query: 1160 IVHFSVYMSPNNLSEAKQEGLMKKFKLTTSISTSNMHLFDSKGVIKKYDTPEQIIEEFFH 981
            I  F VYMS   L   KQEGL+KKFK+TT+I T+NMHLFD KGVIKKYDTPEQI+EEF+H
Sbjct: 960  IPQFMVYMSAEKLLAVKQEGLLKKFKMTTNIGTTNMHLFDPKGVIKKYDTPEQILEEFYH 1019

Query: 980  IRLEFYDKRKKALLANLENDMLKCDNKYRFIRGVVDGSIIVSNRKRADLFLELKEKGFTP 801
            +RLE+Y+KRKKALLANLE D+LKC+NK+RFIR VVDGSI+VSNRKRADL LELK+KGFTP
Sbjct: 1020 LRLEYYEKRKKALLANLEVDLLKCENKWRFIRCVVDGSIVVSNRKRADLLLELKQKGFTP 1079

Query: 800  FPKKKTAAEIAIAGSTDDADESEENNDVAIGKGVSASDYDYLLSLAIGTLTAEKMKELRD 621
            FPKKK AAE+ +AGSTDD  E+EEN   A  +G    DYDYLLSL+IGTLT EKM+EL  
Sbjct: 1080 FPKKKLAAEVDVAGSTDDVYEAEENGATASHEG----DYDYLLSLSIGTLTVEKMRELEA 1135

Query: 620  ERDKLMQEVEELKRATVKSLWMHDLDALESKFIEELNKSEKKWAENRQRILGEAKGTRPV 441
            ERDKL+QE E+LKRA+VKSLWM DLDALE K ++EL K+ ++  ++R +++  AK  RPV
Sbjct: 1136 ERDKLLQEFEDLKRASVKSLWMKDLDALEGK-LDELEKNAEEQEKSRSKVMNNAKLKRPV 1194

Query: 440  QTKPRKNTKKASNK-ESVVEQM--EVSDNTVT 354
               PRKN + A+ K +S   Q+  ++SDN  T
Sbjct: 1195 LKNPRKNKEVANGKAKSAANQVTKQISDNADT 1226


>gb|EPS73185.1| hypothetical protein M569_01571, partial [Genlisea aurea]
          Length = 1258

 Score =  962 bits (2486), Expect = 0.0
 Identities = 472/636 (74%), Positives = 536/636 (84%)
 Frame = -3

Query: 2240 WKQNQGTDVKNWTIKYYKGLGTSTDQEAKEYFEALGRHKKDFVWVDEQDGDAIELAFSKK 2061
            WKQN G+D +NW+IKYYKGLGTSTD EAKEYFE LG+HKKDFVW +++DG+AIELAFSKK
Sbjct: 603  WKQNLGSDSRNWSIKYYKGLGTSTDAEAKEYFEDLGKHKKDFVWGNDEDGEAIELAFSKK 662

Query: 2060 KIEARKNWLRQFEPGTYLCDLEEHIKYRDFVHKELILFSIADLQRSIPSMVDGLKPGQRK 1881
            KIEARKNWLRQFEPGTYL  +E+ IKY DFVHKELILFS+ADLQRSIPSM+DGLKPGQRK
Sbjct: 663  KIEARKNWLRQFEPGTYLDQMEKKIKYSDFVHKELILFSVADLQRSIPSMIDGLKPGQRK 722

Query: 1880 ILFCSFKRNFIKEAKVAQFSGYVSEHSAYHHGEQSLASTIIGMAQDYVGSNNINLLLPNG 1701
            ILFCSFKRNF+KEAKVAQFSGYVSEHSAYHHGEQSLA TIIGMAQD+VGSNNINLLLPNG
Sbjct: 723  ILFCSFKRNFVKEAKVAQFSGYVSEHSAYHHGEQSLAGTIIGMAQDFVGSNNINLLLPNG 782

Query: 1700 QFGTRGQGGKDHASARYIYTQLSSITRFLFPKADDFLLNYLNEDGQSIEPTWYVPTIPMV 1521
            QFGTR QGGKDHASARYI+TQL+ +TRFLFPKADD LL+YLNEDGQSIEPTWY+P IPM 
Sbjct: 783  QFGTRDQGGKDHASARYIFTQLNPVTRFLFPKADDILLDYLNEDGQSIEPTWYMPIIPMA 842

Query: 1520 LVNGSEGIGTGWSTFIPNYNPLDIIANVRHLLNDEPMEPMHPWYKGFIGLIEKTATKEAG 1341
            LVNGS+GIGTGWST IPNYNP DIIANVRHLLNDE M+PM PWY+G+ G IEK+ATKE  
Sbjct: 843  LVNGSDGIGTGWSTSIPNYNPRDIIANVRHLLNDEMMDPMTPWYRGYRGSIEKSATKEL- 901

Query: 1340 NSYTVSGIIEEVDETSLRITELPIRKWTQDYKEFLESVSAENDKSKDPFIEGCRDNSGGE 1161
              YTV+GIIEEVDET+LRITELP+RKWTQDYKEFLESVSAENDKSKDPF++GC D+S  +
Sbjct: 902  -VYTVTGIIEEVDETTLRITELPVRKWTQDYKEFLESVSAENDKSKDPFVQGCSDHSSPQ 960

Query: 1160 IVHFSVYMSPNNLSEAKQEGLMKKFKLTTSISTSNMHLFDSKGVIKKYDTPEQIIEEFFH 981
              HF VYM+  NL  AKQE L+KKFKLT +I T+NMHLFD  G IKKYDTPEQI+EEFFH
Sbjct: 961  FAHFMVYMTAENLLAAKQENLLKKFKLTANICTTNMHLFDRNGAIKKYDTPEQILEEFFH 1020

Query: 980  IRLEFYDKRKKALLANLENDMLKCDNKYRFIRGVVDGSIIVSNRKRADLFLELKEKGFTP 801
            IRLE+Y+KRK  LLANLE D+LKC+NK+RFI+ VVDGSI+VSNRK+ADLFLELK KGFTP
Sbjct: 1021 IRLEYYEKRKATLLANLEIDLLKCENKWRFIKSVVDGSIVVSNRKKADLFLELKNKGFTP 1080

Query: 800  FPKKKTAAEIAIAGSTDDADESEENNDVAIGKGVSASDYDYLLSLAIGTLTAEKMKELRD 621
            FPKKK AAE+   GST+D DE+EEN+ V   +  S  DYDYLLSLAIGTLT EKM ELR 
Sbjct: 1081 FPKKKQAAEVDFVGSTEDLDENEENDGVKTSQEGSIGDYDYLLSLAIGTLTVEKMDELRS 1140

Query: 620  ERDKLMQEVEELKRATVKSLWMHDLDALESKFIEELNKSEKKWAENRQRILGEAKGTRPV 441
            ERDKL  + E+LKRATVKSLW+ DLDALE K ++EL K++ +  +NR   +G  K ++ V
Sbjct: 1141 ERDKLSSDFEDLKRATVKSLWIKDLDALEEK-LDELEKADVEKEKNRSNAVGNTKVSKLV 1199

Query: 440  QTKPRKNTKKASNKESVVEQMEVSDNTVTETDKVGE 333
               PRKN K A+     VE M    N   E + V +
Sbjct: 1200 LKNPRKNNKAANTNVESVENMRCFVNVKCERNVVSK 1235


>ref|XP_002274267.1| PREDICTED: DNA topoisomerase 2 [Vitis vinifera]
          Length = 1489

 Score =  958 bits (2477), Expect = 0.0
 Identities = 490/730 (67%), Positives = 574/730 (78%), Gaps = 8/730 (1%)
 Frame = -3

Query: 2243 TWKQNQGTDVKNWTIKYYKGLGTSTDQEAKEYFEALGRHKKDFVWVDEQDGDAIELAFSK 2064
            +WK++ G +   W+IKYYKGLGTST +E KEYF+ LG+HKKDF+WVDE+DGDAIELAFSK
Sbjct: 591  SWKESLGGNASGWSIKYYKGLGTSTSKEGKEYFKDLGKHKKDFMWVDEKDGDAIELAFSK 650

Query: 2063 KKIEARKNWLRQFEPGTYLCDLEEHIKYRDFVHKELILFSIADLQRSIPSMVDGLKPGQR 1884
            KKIE RKNWLRQF+PGTYL   E+ IKY DFV+KELILFS+ADLQRSIPSMVDGLKPGQR
Sbjct: 651  KKIEERKNWLRQFQPGTYLDQKEKLIKYSDFVNKELILFSMADLQRSIPSMVDGLKPGQR 710

Query: 1883 KILFCSFKRNFIKEAKVAQFSGYVSEHSAYHHGEQSLASTIIGMAQDYVGSNNINLLLPN 1704
            KILFCSFKRNFIKEAK+AQFSGYVSEHSAYHHGEQSLASTIIGMAQD+VGSNNINLLLPN
Sbjct: 711  KILFCSFKRNFIKEAKIAQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPN 770

Query: 1703 GQFGTRGQGGKDHASARYIYTQLSSITRFLFPKADDFLLNYLNEDGQSIEPTWYVPTIPM 1524
            GQFGTR QGGKDHASARYIYT+LS ITRFLFPK DD LL+YLNEDGQSIEPTWYVPTIPM
Sbjct: 771  GQFGTRHQGGKDHASARYIYTRLSPITRFLFPKDDDILLDYLNEDGQSIEPTWYVPTIPM 830

Query: 1523 VLVNGSEGIGTGWSTFIPNYNPLDIIANVRHLLNDEPMEPMHPWYKGFIGLIEKT-ATKE 1347
            VLVNGSEGIGTGWS+ IPNYNP DIIANVR LLN E MEPM PWY+GF G IEKT  TK+
Sbjct: 831  VLVNGSEGIGTGWSSSIPNYNPRDIIANVRRLLNGEMMEPMDPWYRGFRGTIEKTDPTKQ 890

Query: 1346 AGNSYTVSGIIEEVDETSLRITELPIRKWTQDYKEFLESVSAENDKSKDPFIEGCRDNSG 1167
                YTV GIIEEV+ET+LRI+ELP+RKWTQDYKEFLES+   NDK KDPFI+  ++++ 
Sbjct: 891  ESVGYTVKGIIEEVNETTLRISELPVRKWTQDYKEFLESIMTGNDKIKDPFIKDYKEHND 950

Query: 1166 GEIVHFSVYMSPNNLSEAKQEGLMKKFKLTTSISTSNMHLFDSKGVIKKYDTPEQIIEEF 987
               VHF V MS  NL  AKQEGL++KFKLTT ISTSNMHLFDS G IKKY+TPEQI+EEF
Sbjct: 951  DTTVHFEVIMSEENLLMAKQEGLLQKFKLTTKISTSNMHLFDSNGTIKKYETPEQILEEF 1010

Query: 986  FHIRLEFYDKRKKALLANLENDMLKCDNKYRFIRGVVDGSIIVSNRKRADLFLELKEKGF 807
            FH+RLEFY+KRK+ LL NLE ++LK +NK RFI GVV G IIVSNRKRADLF EL +KGF
Sbjct: 1011 FHLRLEFYEKRKRVLLDNLELELLKLENKVRFILGVVRGEIIVSNRKRADLFHELHQKGF 1070

Query: 806  TPFPKKKTAAEIAIAGSTDDADESEENNDVAIGKGVSASDYDYLLSLAIGTLTAEKMKEL 627
            TPFPKK  + EIA+AG+TDD +E+EEN D     GV A+DY+YLLS+AIGTLT EK++EL
Sbjct: 1071 TPFPKKSKSVEIAVAGATDDTEEAEENTDAVSKGGVRATDYEYLLSMAIGTLTLEKVQEL 1130

Query: 626  RDERDKLMQEVEELKRATVKSLWMHDLDALESKFIEELNKSEKKWAENRQ----RILGEA 459
              +RDKL + V++LK+AT K+LW+ DLDALE + ++E +K++ +  E R+    R++ EA
Sbjct: 1131 CADRDKLNKGVDDLKKATPKALWITDLDALERE-LDEQDKNDARAEETRKQLKSRVMSEA 1189

Query: 458  --KGTRPVQTKPRKNTKKASNKESVVEQMEVSDNTVTETDKVGEVXXXXXXXXXXXXXXX 285
              K +R     PRKN KKA+N E   E M+VS ++  E + V EV               
Sbjct: 1190 GMKVSRQAPKNPRKNNKKANNAEPAAETMDVSASSAMEMESVPEVVKPKGRAAPRKAPAK 1249

Query: 284  XXXXXXXXXXXXXXXXXXDLRHRLAAYNFDSSPDRSEDMETEQPQMP-TKKKEPNRRTAA 108
                              +L+ RLAAYN +SSPD S  ME E PQ+P  +KKEP+RR AA
Sbjct: 1250 KKEMPTSVLKDEDDDEVHELKERLAAYNLESSPDGSAAMEAEVPQVPAARKKEPSRRAAA 1309

Query: 107  QKKPLSTVSE 78
            QKKPL++ +E
Sbjct: 1310 QKKPLASFTE 1319


>ref|XP_010241214.1| PREDICTED: DNA topoisomerase 2-like isoform X2 [Nelumbo nucifera]
          Length = 1503

 Score =  950 bits (2456), Expect = 0.0
 Identities = 487/725 (67%), Positives = 569/725 (78%), Gaps = 7/725 (0%)
 Frame = -3

Query: 2243 TWKQNQGTDVKNWTIKYYKGLGTSTDQEAKEYFEALGRHKKDFVWVDEQDGDAIELAFSK 2064
            +WK   G +   W+IKYYKGLGTST +E KEYF+ L +HKKDF+WVD++DGDAIELAFSK
Sbjct: 595  SWKX-LGGNASGWSIKYYKGLGTSTSKEGKEYFKDLHKHKKDFLWVDDRDGDAIELAFSK 653

Query: 2063 KKIEARKNWLRQFEPGTYLCDLEEHIKYRDFVHKELILFSIADLQRSIPSMVDGLKPGQR 1884
            KKIEARKNWLRQFEPGT L   E+ IKY DFV+KELILFS+ADLQRSIPSMVDGLKPGQR
Sbjct: 654  KKIEARKNWLRQFEPGTCLDQKEKLIKYSDFVNKELILFSMADLQRSIPSMVDGLKPGQR 713

Query: 1883 KILFCSFKRNFIKEAKVAQFSGYVSEHSAYHHGEQSLASTIIGMAQDYVGSNNINLLLPN 1704
            KILFC+FKRN IKEAKVAQFSGYVSEHSAYHHGEQSL STIIGMAQDYVGSNNINL  PN
Sbjct: 714  KILFCAFKRNLIKEAKVAQFSGYVSEHSAYHHGEQSLMSTIIGMAQDYVGSNNINLFQPN 773

Query: 1703 GQFGTRGQGGKDHASARYIYTQLSSITRFLFPKADDFLLNYLNEDGQSIEPTWYVPTIPM 1524
            GQFGTR QGGKDHASARYIYT+LS ITRFLFPK DD LL+YLNEDGQSIEPTWY+P IP 
Sbjct: 774  GQFGTRHQGGKDHASARYIYTRLSPITRFLFPKGDDILLDYLNEDGQSIEPTWYMPIIPT 833

Query: 1523 VLVNGSEGIGTGWSTFIPNYNPLDIIANVRHLLNDEPMEPMHPWYKGFIGLIEKTATKEA 1344
            VLVNGSEGIGTGWS++IPNYNP DI+AN++ LLN EPMEPM PWYKGF GLIEKTATKEA
Sbjct: 834  VLVNGSEGIGTGWSSYIPNYNPRDIVANIKRLLNGEPMEPMDPWYKGFKGLIEKTATKEA 893

Query: 1343 GNSYTVSGIIEEVDETSLRITELPIRKWTQDYKEFLESVSAENDKSKDPFIEGCRDNSGG 1164
            G+SYTVSGIIEE++ET+LRITELPIR+WTQDYKEFLES+   NDK K+PFI+  ++++  
Sbjct: 894  GSSYTVSGIIEEINETTLRITELPIRRWTQDYKEFLESIMTGNDKIKEPFIKDYKEHNDD 953

Query: 1163 EIVHFSVYMSPNNLSEAKQEGLMKKFKLTTSISTSNMHLFDSKGVIKKYDTPEQIIEEFF 984
              VHF + +S  NL  AKQEGLMKKFKLTT+ISTSNMHLFD KG IKKYD PEQI+EEFF
Sbjct: 954  TTVHFEIILSEENLMMAKQEGLMKKFKLTTTISTSNMHLFDPKGTIKKYDNPEQILEEFF 1013

Query: 983  HIRLEFYDKRKKALLANLENDMLKCDNKYRFIRGVVDGSIIVSNRKRADLFLELKEKGFT 804
            H+RLEFY+KRKK  L NLE D+LK DNK RFI GVV G IIVSNRKR DLFLEL++KGFT
Sbjct: 1014 HLRLEFYEKRKKTQLDNLELDLLKLDNKVRFILGVVKGEIIVSNRKRVDLFLELQQKGFT 1073

Query: 803  PFPKKKTAAEIAIAGSTDDADESEENNDVAIGKGVSASDYDYLLSLAIGTLTAEKMKELR 624
            PFPKK  A E A+AG+ +D +E+EEN++V   +GV ASDY+YLLS+AIGTLT EK++EL 
Sbjct: 1074 PFPKKTKALEAAVAGANEDGEENEENSEVVSSRGVRASDYEYLLSMAIGTLTLEKVQELC 1133

Query: 623  DERDKLMQEVEELKRATVKSLWMHDLDALESKFIEELNKSEKKWAENRQ----RILGEA- 459
             +RDKL  EVEEL++AT  SLWM+DLDALE K ++E +K++ +  E R+    R++ EA 
Sbjct: 1134 SDRDKLNHEVEELRKATPNSLWMNDLDALE-KELDEQDKNDAQAEEARKELKNRVMSEAG 1192

Query: 458  -KGTRPVQTKPRK-NTKKASNKESVVEQMEVSDNTVTETDKVGEVXXXXXXXXXXXXXXX 285
             K +R     PRK N KK S  E+V E +  S +  +  + V EV               
Sbjct: 1193 MKASRQAPKNPRKTNAKKPSTSETVTESVAAS-SVGSAMETVPEVVKPKGRGGRPKKAPA 1251

Query: 284  XXXXXXXXXXXXXXXXXXDLRHRLAAYNFDSSPDRSEDMETEQPQMPTKKKEPNRRTAAQ 105
                              +L+ RLAAYN DSSP++S  METE  ++P KKKEP++R AAQ
Sbjct: 1252 KKDNMRLVDSDEDDVDVIELKERLAAYNLDSSPEQSAVMETEVAKVPAKKKEPSKRAAAQ 1311

Query: 104  KKPLS 90
            K+P S
Sbjct: 1312 KQPSS 1316


>emb|CDP07797.1| unnamed protein product [Coffea canephora]
          Length = 1486

 Score =  947 bits (2447), Expect = 0.0
 Identities = 487/731 (66%), Positives = 574/731 (78%), Gaps = 9/731 (1%)
 Frame = -3

Query: 2243 TWKQNQGTDVKNWTIKYYKGLGTSTDQEAKEYFEALGRHKKDFVWVDEQDGDAIELAFSK 2064
            +WK++   +   W+IKYYKGLGTST +E KEYF+ LG+HKKDF+WVD+ DG+AIELAFSK
Sbjct: 592  SWKESLSGNATGWSIKYYKGLGTSTSKEGKEYFKDLGKHKKDFIWVDDNDGEAIELAFSK 651

Query: 2063 KKIEARKNWLRQFEPGTYLCDLEEHIKYRDFVHKELILFSIADLQRSIPSMVDGLKPGQR 1884
            KKIEARKNWLRQFEPGTYL   E+ IKY DF++KELILFS+ADLQRSIPSMVDGLKPGQR
Sbjct: 652  KKIEARKNWLRQFEPGTYLDQKEKLIKYSDFINKELILFSLADLQRSIPSMVDGLKPGQR 711

Query: 1883 KILFCSFKRNFIKEAKVAQFSGYVSEHSAYHHGEQSLASTIIGMAQDYVGSNNINLLLPN 1704
            KILFCSFKRNF+KEAKVAQFSGYVSEHSAYHHGEQSLAS IIGMAQD+VGSNNINLL PN
Sbjct: 712  KILFCSFKRNFVKEAKVAQFSGYVSEHSAYHHGEQSLASAIIGMAQDFVGSNNINLLQPN 771

Query: 1703 GQFGTRGQGGKDHASARYIYTQLSSITRFLFPKADDFLLNYLNEDGQSIEPTWYVPTIPM 1524
            GQFGTR QGGKDHASARY+YT+LS ITR LFPK DD LL+YLNEDGQSIEPTWY+P IPM
Sbjct: 772  GQFGTRNQGGKDHASARYVYTRLSPITRSLFPKDDDILLDYLNEDGQSIEPTWYMPIIPM 831

Query: 1523 VLVNGSEGIGTGWSTFIPNYNPLDIIANVRHLLNDEPMEPMHPWYKGFIGLIEKTATKEA 1344
            VLVNGSEGIGTGWS++IPNYNP DII N+R LLN+EPMEPM PWYKGF G IEKTATKEA
Sbjct: 832  VLVNGSEGIGTGWSSYIPNYNPRDIIGNIRRLLNNEPMEPMEPWYKGFRGTIEKTATKEA 891

Query: 1343 GNSYTVSGIIEEVDETSLRITELPIRKWTQDYKEFLESVSAENDKSKDPFIEGCRDNSGG 1164
            G SYTVSGI+EEVDET++R+TELP+RKWTQDYKEFLES+   N+K KDPFI+  RD++  
Sbjct: 892  GASYTVSGIVEEVDETTIRVTELPVRKWTQDYKEFLESIMMGNEKVKDPFIKEFRDHTDD 951

Query: 1163 EIVHFSVYMSPNNLSEAKQEGLMKKFKLTTSISTSNMHLFDSKGVIKKYDTPEQIIEEFF 984
              V+  + MS  NL  AKQEGL+KKFKLTT+ISTSNMHLFDS+G+IKK+D PEQI+EEFF
Sbjct: 952  TTVYLDIIMSEENLLMAKQEGLLKKFKLTTTISTSNMHLFDSQGIIKKFDNPEQILEEFF 1011

Query: 983  HIRLEFYDKRKKALLANLENDMLKCDNKYRFIRGVVDGSIIVSNRKRADLFLELKEKGFT 804
            H+RLEFY+KRKK LL NL+ ++LK DNK RFI  VV+GSIIVSNRKRADLFLELKEKGFT
Sbjct: 1012 HLRLEFYEKRKKVLLDNLQLELLKLDNKVRFILAVVEGSIIVSNRKRADLFLELKEKGFT 1071

Query: 803  PFPKKKTAAEIAIAGSTDDADESEENNDVAIGKGVSASDYDYLLSLAIGTLTAEKMKELR 624
            PFPKKK + E A+AGS +DA+E+EE+++VA  KGV ASDY+YL+S+AIG+LT EK++EL 
Sbjct: 1072 PFPKKK-SVEAAVAGSIEDAEETEESSEVATSKGVRASDYEYLISMAIGSLTLEKVQELC 1130

Query: 623  DERDKLMQEVEELKRATVKSLWMHDLDALESKFIEELNKSEKKWAENRQRILGEA----- 459
             +RDKL  EV++L +AT KSLW  DLDALES+ ++E + S+ +    R+ +  +A     
Sbjct: 1131 ADRDKLKGEVDDLIKATPKSLWTKDLDALESQ-LDEQDISDAQAEAARKEMRSKAMKDDG 1189

Query: 458  -KGTRPVQTKPRKNTKKASNKESVVEQMEVSDNTVTETDKVGEV--XXXXXXXXXXXXXX 288
             K TR     PRK  KKASN E   E ME+S ++  ET+ V EV                
Sbjct: 1190 PKPTRQAPKNPRKYNKKASNTEPTTEPMEISSSSALETNNVVEVAKPKGKAGPKKAPARK 1249

Query: 287  XXXXXXXXXXXXXXXXXXXDLRHRLAAYNF-DSSPDRSEDMETEQPQMPTKKKEPNRRTA 111
                                L+ RLAAYN   SSPD+SE METE P     K+EP++R A
Sbjct: 1250 GKTFSVLRDEDDEDDDEVLALKDRLAAYNLGSSSPDQSETMETEIP-----KREPSKR-A 1303

Query: 110  AQKKPLSTVSE 78
              KKPL +V+E
Sbjct: 1304 TTKKPLVSVTE 1314


>ref|XP_010241213.1| PREDICTED: DNA topoisomerase 2-like isoform X1 [Nelumbo nucifera]
          Length = 1504

 Score =  946 bits (2444), Expect = 0.0
 Identities = 485/725 (66%), Positives = 564/725 (77%), Gaps = 7/725 (0%)
 Frame = -3

Query: 2243 TWKQNQGTDVKNWTIKYYKGLGTSTDQEAKEYFEALGRHKKDFVWVDEQDGDAIELAFSK 2064
            +WK   G +   W+IKYYKGLGTST +E KEYF+ L +HKKDF+WVD++DGDAIELAFSK
Sbjct: 595  SWKX-LGGNASGWSIKYYKGLGTSTSKEGKEYFKDLHKHKKDFLWVDDRDGDAIELAFSK 653

Query: 2063 KKIEARKNWLRQFEPGTYLCDLEEHIKYRDFVHKELILFSIADLQRSIPSMVDGLKPGQR 1884
            KKIEARKNWLRQFEPGT L   E+ IKY DFV+KELILFS+ADLQRSIPSMVDGLKPGQR
Sbjct: 654  KKIEARKNWLRQFEPGTCLDQKEKLIKYSDFVNKELILFSMADLQRSIPSMVDGLKPGQR 713

Query: 1883 KILFCSFKRNFIKEAKVAQFSGYVSEHSAYHHGEQSLASTIIGMAQDYVGSNNINLLLPN 1704
            KILFC+FKRN IKEAKVAQFSGYVSEHSAYHHGEQSL STIIGMAQDYVGSNNINL  PN
Sbjct: 714  KILFCAFKRNLIKEAKVAQFSGYVSEHSAYHHGEQSLMSTIIGMAQDYVGSNNINLFQPN 773

Query: 1703 GQFGTRGQGGKDHASARYIYTQLSSITRFLFPKADDFLLNYLNEDGQSIEPTWYVPTIPM 1524
            GQFGTR QGGKDHASARYIYT+LS ITRFLFPK DD LL+YLNEDGQSIEPTWY+P IP 
Sbjct: 774  GQFGTRHQGGKDHASARYIYTRLSPITRFLFPKGDDILLDYLNEDGQSIEPTWYMPIIPT 833

Query: 1523 VLVNGSEGIGTGWSTFIPNYNPLDIIANVRHLLNDEPMEPMHPWYKGFIGLIEKTATKEA 1344
            VLVNGSEGIGTGWS++IPNYNP DI+AN++ LLN EPMEPM PWYKGF GLIEKTATKEA
Sbjct: 834  VLVNGSEGIGTGWSSYIPNYNPRDIVANIKRLLNGEPMEPMDPWYKGFKGLIEKTATKEA 893

Query: 1343 GNSYTVSGIIEEVDETSLRITELPIRKWTQDYKEFLESVSAENDKSKDPFIEGCRDNSGG 1164
            G+SYTVSGIIEE++ET+LRITELPIR+WTQDYKEFLES+   NDK K+PFI+  ++++  
Sbjct: 894  GSSYTVSGIIEEINETTLRITELPIRRWTQDYKEFLESIMTGNDKIKEPFIKDYKEHNDD 953

Query: 1163 EIVHFSVYMSPNNLSEAKQEGLMKKFKLTTSISTSNMHLFDSKGVIKKYDTPEQIIEEFF 984
              VHF + +S  NL  AKQEGLMKKFKLTT+ISTSNMHLFD KG IKKYD PEQI+EEFF
Sbjct: 954  TTVHFEIILSEENLMMAKQEGLMKKFKLTTTISTSNMHLFDPKGTIKKYDNPEQILEEFF 1013

Query: 983  HIRLEFYDKRKKALLANLENDMLKCDNKYRFIRGVVDGSIIVSNRKRADLFLELKEKGFT 804
            H+RLEFY+KRKK  L NLE D+LK DNK RFI GVV G IIVSNRKR DLFLEL++KGFT
Sbjct: 1014 HLRLEFYEKRKKTQLDNLELDLLKLDNKVRFILGVVKGEIIVSNRKRVDLFLELQQKGFT 1073

Query: 803  PFPKKKTAAEIAIAGSTDDADESEENNDVAIGKGVSASDYDYLLSLAIGTLTAEKMKELR 624
            PFPKK  A E A+AG+ +D +E+EEN++V   +GV ASDY+YLLS+AIGTLT EK++EL 
Sbjct: 1074 PFPKKTKALEAAVAGANEDGEENEENSEVVSSRGVRASDYEYLLSMAIGTLTLEKVQELC 1133

Query: 623  DERDKLMQEVEELKRATVKSLWMHDLDALESKFIEELNKSEKKWAENRQ----RILGEA- 459
             +RDKL  EVEEL++AT  SLWM+DLDALE K ++E +K++ +  E R+    R++ EA 
Sbjct: 1134 SDRDKLNHEVEELRKATPNSLWMNDLDALE-KELDEQDKNDAQAEEARKELKNRVMSEAG 1192

Query: 458  -KGTRPVQTKPRK-NTKKASNKESVVEQMEVSDNTVTETDKVGEVXXXXXXXXXXXXXXX 285
             K +R     PRK N KK S  E+V E +  S            V               
Sbjct: 1193 MKASRQAPKNPRKTNAKKPSTSETVTESVAASSVGSAMETVPEVVKPKGRGGRPKKAPAK 1252

Query: 284  XXXXXXXXXXXXXXXXXXDLRHRLAAYNFDSSPDRSEDMETEQPQMPTKKKEPNRRTAAQ 105
                              +L+ RLAAYN DSSP++S  METE  ++P KKKEP++R AAQ
Sbjct: 1253 KQDNMRLVDSDEDDVDVIELKERLAAYNLDSSPEQSAVMETEVAKVPAKKKEPSKRAAAQ 1312

Query: 104  KKPLS 90
            K+P S
Sbjct: 1313 KQPSS 1317


>ref|XP_022896608.1| DNA topoisomerase 2 [Olea europaea var. sylvestris]
          Length = 1459

 Score =  937 bits (2421), Expect = 0.0
 Identities = 474/724 (65%), Positives = 562/724 (77%), Gaps = 2/724 (0%)
 Frame = -3

Query: 2243 TWKQNQGTDVKNWTIKYYKGLGTSTDQEAKEYFEALGRHKKDFVWVDEQDGDAIELAFSK 2064
            +WK++ G   KNW+IKYYKGLGTSTD+E KEYF+ L +HKKDFVW D+ DG+AIELAFSK
Sbjct: 587  SWKESLGDRAKNWSIKYYKGLGTSTDKEGKEYFKDLEKHKKDFVWGDDHDGEAIELAFSK 646

Query: 2063 KKIEARKNWLRQFEPGTYLCDLEEHIKYRDFVHKELILFSIADLQRSIPSMVDGLKPGQR 1884
            KKIEARKNWLRQFEPGTYL   E+ IKYRDFV+KELILFS+ADLQRSIPSMVDGLKPGQR
Sbjct: 647  KKIEARKNWLRQFEPGTYLDQEEKLIKYRDFVNKELILFSMADLQRSIPSMVDGLKPGQR 706

Query: 1883 KILFCSFKRNFIKEAKVAQFSGYVSEHSAYHHGEQSLASTIIGMAQDYVGSNNINLLLPN 1704
            KILFC+FKRNF+ EAKV QFSGYVSEHSAYHHGEQSLASTIIGMAQ YVGSNNIN+L PN
Sbjct: 707  KILFCAFKRNFVHEAKVGQFSGYVSEHSAYHHGEQSLASTIIGMAQKYVGSNNINILKPN 766

Query: 1703 GQFGTRGQGGKDHASARYIYTQLSSITRFLFPKADDFLLNYLNEDGQSIEPTWYVPTIPM 1524
            GQFGTR QGGKDHASARYI+TQLS+ITRFLFPK DD +L+Y NEDGQ+IEPTWYVP IPM
Sbjct: 767  GQFGTRNQGGKDHASARYIFTQLSAITRFLFPKDDDIILDYQNEDGQTIEPTWYVPIIPM 826

Query: 1523 VLVNGSEGIGTGWSTFIPNYNPLDIIANVRHLLNDEPMEPMHPWYKGFIGLIEKTATKEA 1344
            VLVNGSEGIGTGWS+F+PNYNP DIIANVRH+LNDEPMEPM PWYKGF G IEKTATKEA
Sbjct: 827  VLVNGSEGIGTGWSSFVPNYNPRDIIANVRHMLNDEPMEPMDPWYKGFSGTIEKTATKEA 886

Query: 1343 GNSYTVSGIIEEVDETSLRITELPIRKWTQDYKEFLESVSAENDKSKDPFIEGCRDNSGG 1164
            G +YT +GIIEEV +T+LRITELPIR+WTQDYK++LES+         PFIE  R+    
Sbjct: 887  GATYTATGIIEEVSDTTLRITELPIRRWTQDYKDYLESLY--------PFIEEVREYHTT 938

Query: 1163 EIVHFSVYMSPNNLSEAKQEGLMKKFKLTTSISTSNMHLFDSKGVIKKYDTPEQIIEEFF 984
            + V+F + +S  N+  AKQEGL+KKFKLTT+ISTSNMHLFDSKGVIKKYDTPE+I+E+F+
Sbjct: 939  DSVNFEIDLSEENMMIAKQEGLLKKFKLTTTISTSNMHLFDSKGVIKKYDTPEKILEDFY 998

Query: 983  HIRLEFYDKRKKALLANLENDMLKCDNKYRFIRGVVDGSIIVSNRKRADLFLELKEKGFT 804
             IR EFY+KRKK L+ NLE ++L  +NK RFI  VV+G IIVSNR+RADL LELK+KGFT
Sbjct: 999  SIRFEFYEKRKKVLMDNLERELLILENKVRFILNVVEGKIIVSNRRRADLVLELKDKGFT 1058

Query: 803  PFPKKKTAAEIAIAGSTDDADESEENNDVAIGKGVSASDYDYLLSLAIGTLTAEKMKELR 624
            PFPKK    E+++AGS+D  +E+EEN+D+A  +GV ASDYDYLLS++IG+LT EK++EL 
Sbjct: 1059 PFPKKTKTVEVSVAGSSDVPEETEENSDMANSQGVRASDYDYLLSMSIGSLTIEKVQELC 1118

Query: 623  DERDKLMQEVEELKRATVKSLWMHDLDALESKFIEELNKSEKKWAENRQRILGE--AKGT 450
            + RDKL+QEVEE+++AT+KSLW+ DLDALE++ ++E +K +    E+   I  +   K  
Sbjct: 1119 NNRDKLIQEVEEMRQATIKSLWIKDLDALETE-LDEQDKRDALAEEDELEIKPKRGRKAP 1177

Query: 449  RPVQTKPRKNTKKASNKESVVEQMEVSDNTVTETDKVGEVXXXXXXXXXXXXXXXXXXXX 270
            +P    PRKN KK    ESVVE ME+S N+  E D                         
Sbjct: 1178 KPAMKNPRKNNKKVGKTESVVEPMEISTNSEIEKDNA--------RVAVQKKAPRKGKSV 1229

Query: 269  XXXXXXXXXXXXXDLRHRLAAYNFDSSPDRSEDMETEQPQMPTKKKEPNRRTAAQKKPLS 90
                          L  R+AAYN DSSPD  E  E E  ++  KKK P +R AA KKPLS
Sbjct: 1230 AALKDEEDDDEILALNERIAAYNLDSSPDHEEVAEAEVSEVQIKKKGPTKRAAATKKPLS 1289

Query: 89   TVSE 78
            TV+E
Sbjct: 1290 TVTE 1293


>gb|OVA19386.1| DNA topoisomerase II [Macleaya cordata]
          Length = 1515

 Score =  935 bits (2416), Expect = 0.0
 Identities = 479/733 (65%), Positives = 568/733 (77%), Gaps = 12/733 (1%)
 Frame = -3

Query: 2240 WKQNQGTDVKNWTIKYYKGLGTSTDQEAKEYFEALGRHKKDFVWVDEQDGDAIELAFSKK 2061
            WK++ G +   W+IKYYKGLGTST +E KEYF+ L +H+KDF+WVDEQDGDAI+LAFSKK
Sbjct: 623  WKESLGGNASGWSIKYYKGLGTSTSKEGKEYFKDLEKHRKDFMWVDEQDGDAIDLAFSKK 682

Query: 2060 KIEARKNWLRQFEPGTYLCDLEEHIKYRDFVHKELILFSIADLQRSIPSMVDGLKPGQRK 1881
            KIEARKNWLRQFEPGTYL   E+ IKY DFV+KELILFS+ADLQRSIPSMVDGLKPGQRK
Sbjct: 683  KIEARKNWLRQFEPGTYLDQKEKLIKYSDFVNKELILFSMADLQRSIPSMVDGLKPGQRK 742

Query: 1880 ILFCSFKRNFIKEAKVAQFSGYVSEHSAYHHGEQSLASTIIGMAQDYVGSNNINLLLPNG 1701
            ILFCSFKRNF+KEAKVAQFSGYVSEHSAYHHGEQSLA TIIGMAQDYVGSNNINLL PNG
Sbjct: 743  ILFCSFKRNFVKEAKVAQFSGYVSEHSAYHHGEQSLAGTIIGMAQDYVGSNNINLLQPNG 802

Query: 1700 QFGTRGQGGKDHASARYIYTQLSSITRFLFPKADDFLLNYLNEDGQSIEPTWYVPTIPMV 1521
            QFGTR QGGKDHASARYIYT+LS ITRFLFPK DD LL+YLNEDGQSIEPTWYVP IP V
Sbjct: 803  QFGTRHQGGKDHASARYIYTRLSPITRFLFPKDDDILLDYLNEDGQSIEPTWYVPVIPTV 862

Query: 1520 LVNGSEGIGTGWSTFIPNYNPLDIIANVRHLLNDEPMEPMHPWYKGFIGLIEKTATKEAG 1341
            LVNGSEGIGTGWS +IPNYNP DI+ NV+ LLN EPMEPM PWYKGF G IEKTATKE G
Sbjct: 863  LVNGSEGIGTGWSCYIPNYNPRDIVENVKRLLNGEPMEPMDPWYKGFKGRIEKTATKEGG 922

Query: 1340 NSYTVSGIIEEVDETSLRITELPIRKWTQDYKEFLESVSAENDKSKDPFIEGCRDNSGGE 1161
             SYTVSGIIEEV+ET+LRI+ELP+R+WTQDYKEFLES+   NDK K+PFI+  R+++   
Sbjct: 923  VSYTVSGIIEEVNETTLRISELPVRRWTQDYKEFLESIMTGNDKIKEPFIKDYREHNDDT 982

Query: 1160 IVHFSVYMSPNNLSEAKQEGLMKKFKLTTSISTSNMHLFDSKGVIKKYDTPEQIIEEFFH 981
             VHF V +S  NL  AKQEGL+KKFKLTT++STSNMHLFD KGVIKKYD PEQI+EEFFH
Sbjct: 983  TVHFEVILSEENLVMAKQEGLLKKFKLTTTVSTSNMHLFDPKGVIKKYDNPEQILEEFFH 1042

Query: 980  IRLEFYDKRKKALLANLENDMLKCDNKYRFIRGVVDGSIIVSNRKRADLFLELKEKGFTP 801
            +RLEFY+KRK+ LL NLE ++LK DNK RFI GVV G IIVSNRKRADLFLEL++KGFTP
Sbjct: 1043 LRLEFYEKRKRVLLENLELELLKLDNKVRFILGVVKGEIIVSNRKRADLFLELQQKGFTP 1102

Query: 800  FPKKKTAAEIAIAGSTDDADESEENNDVAIGKGVSASDYDYLLSLAIGTLTAEKMKELRD 621
            FPKK    E  +AG+T+D +E+E+N++    +GV ASDY+YLLS+AIGTLT EK++EL +
Sbjct: 1103 FPKKTKLVEAVVAGATEDTEENEDNSEALSSRGVRASDYEYLLSMAIGTLTLEKVQELCN 1162

Query: 620  ERDKLMQEVEELKRATVKSLWMHDLDALESKFIEELNKSEKKWAENRQ----RILGEA-- 459
            ++ +L  EV+EL+RAT KSLW  DLDALE +F +E +K++ K  E R+    +++ EA  
Sbjct: 1163 DKQRLDGEVDELRRATSKSLWKKDLDALEKEF-DEQDKNDSKAEEARKVMKSKVMKEAGM 1221

Query: 458  KGTRPVQTKPRK-NTKKASNKESVVEQMEVSDNTVTETDKVGEVXXXXXXXXXXXXXXXX 282
            K ++PV   PRK NTKK +N  +V    +VS  +  E + + E                 
Sbjct: 1222 KDSKPVAKNPRKNNTKKVNNPAAVAASAQVS--STMEIENISEAAKPKGRGGPRKAPAKK 1279

Query: 281  XXXXXXXXXXXXXXXXXDLRHRLAAYNFDSSPDRSE-----DMETEQPQMPTKKKEPNRR 117
                             +L+ RLAAYN DSSP++S       METE   +  K KE ++ 
Sbjct: 1280 GKPALVDSDDEDDDEILELKERLAAYNLDSSPEQSSAGPVAAMETESGIVRAKNKETSKM 1339

Query: 116  TAAQKKPLSTVSE 78
             +AQKK  +T++E
Sbjct: 1340 VSAQKK--ATITE 1350


>ref|XP_015881654.1| PREDICTED: DNA topoisomerase 2 isoform X2 [Ziziphus jujuba]
          Length = 1486

 Score =  931 bits (2405), Expect = 0.0
 Identities = 478/730 (65%), Positives = 569/730 (77%), Gaps = 8/730 (1%)
 Frame = -3

Query: 2243 TWKQNQGTDVKNWTIKYYKGLGTSTDQEAKEYFEALGRHKKDFVWVDEQDGDAIELAFSK 2064
            +W+++   +   W+IKYYKGLGTST +E +EYF+ L +H+KDF+WVD+QDG AIELAFSK
Sbjct: 600  SWRESLRGNASGWSIKYYKGLGTSTSKEGREYFQNLDKHRKDFLWVDDQDGAAIELAFSK 659

Query: 2063 KKIEARKNWLRQFEPGTYLCDLEEHIKYRDFVHKELILFSIADLQRSIPSMVDGLKPGQR 1884
            KKIE RKNWLRQFEPGT+L   E+ IKY DFVHKELILFS+ADLQRSIPSMVDGLKPGQR
Sbjct: 660  KKIEERKNWLRQFEPGTHLDQKEKLIKYSDFVHKELILFSVADLQRSIPSMVDGLKPGQR 719

Query: 1883 KILFCSFKRNFIKEAKVAQFSGYVSEHSAYHHGEQSLASTIIGMAQDYVGSNNINLLLPN 1704
            KILFCSFKRNF KEAKVAQFSGYVSEHSAYHHGEQSLASTIIGMAQDYVGSNNINLL PN
Sbjct: 720  KILFCSFKRNFFKEAKVAQFSGYVSEHSAYHHGEQSLASTIIGMAQDYVGSNNINLLQPN 779

Query: 1703 GQFGTRGQGGKDHASARYIYTQLSSITRFLFPKADDFLLNYLNEDGQSIEPTWYVPTIPM 1524
            GQFGTR  GGKDHASARYI+T+LS ITRFLFPK DD LL+YLNEDGQ+IEPTWYVP IP 
Sbjct: 780  GQFGTRNLGGKDHASARYIFTRLSPITRFLFPKDDDKLLDYLNEDGQTIEPTWYVPIIPT 839

Query: 1523 VLVNGSEGIGTGWSTFIPNYNPLDIIANVRHLLNDEPMEPMHPWYKGFIGLIEKTATKEA 1344
            VLVNGSEGIGTGWS++IPNYNP DI+AN+R LLN   M PM PWY+GF G IEKT  KEA
Sbjct: 840  VLVNGSEGIGTGWSSYIPNYNPRDIVANIRRLLNGHSMVPMDPWYRGFKGTIEKT-VKEA 898

Query: 1343 GNSYTVSGIIEEVDETSLRITELPIRKWTQDYKEFLESVSAENDKSKDPFIEGCRDNSGG 1164
            G SYT+SGI+EEV+ET++RITELPIRKWTQDYKEFLES+S  NDK+KDPFIEG   +S  
Sbjct: 899  GVSYTISGILEEVNETTIRITELPIRKWTQDYKEFLESISQGNDKAKDPFIEGFTQHSDH 958

Query: 1163 EIVHFSVYMSPNNLSEAKQEGLMKKFKLTTSISTSNMHLFDSKGVIKKYDTPEQIIEEFF 984
              V   V+M   NL  AKQEGL+KKFKLTT+ISTSNMHLFD+KGVIKKYDTPEQI+EEFF
Sbjct: 959  ITVDILVHMPEENLVAAKQEGLLKKFKLTTTISTSNMHLFDAKGVIKKYDTPEQILEEFF 1018

Query: 983  HIRLEFYDKRKKALLANLENDMLKCDNKYRFIRGVVDGSIIVSNRKRADLFLELKEKGFT 804
            H+RLEFY+KRK+ LL NLE ++LK +NK RFI GVV+  IIVSNRKRADLFLEL++KGFT
Sbjct: 1019 HLRLEFYEKRKQVLLDNLEMELLKLENKVRFILGVVNEEIIVSNRKRADLFLELQQKGFT 1078

Query: 803  PFPKKKTAAEIAIAGSTDDADESEENNDVAIGKGVSASDYDYLLSLAIGTLTAEKMKELR 624
            PFPKK  + E  +AG+TD  +E+E+N++     GV  SDY+YLLS+AIGTLT EK++ L 
Sbjct: 1079 PFPKKAKSVEPEVAGATDYTEETEDNSN---PDGVRISDYEYLLSMAIGTLTLEKVQALC 1135

Query: 623  DERDKLMQEVEELKRATVKSLWMHDLDALESKFIEELNKSEKKWAENRQRI---LGEAKG 453
             ERDKL  EV++L++AT KSLW  DLDAL+ K ++EL+K++ +  + R+++   L  A  
Sbjct: 1136 AERDKLNGEVDDLRKATPKSLWEKDLDALD-KELDELDKNDAQAEDARKKLKSQLNPAAV 1194

Query: 452  TR--PVQTKPRKNTKKASNKESVVEQMEVSDNTVTETDKVGEVXXXXXXXXXXXXXXXXX 279
            T+       PRKN KKA+N E+VVE ME + ++  E +K  EV                 
Sbjct: 1195 TKFAKAPKNPRKNNKKANNAEAVVEMMETTSSSTMEMEKAPEVVKPKGRAVSRKAPTKKE 1254

Query: 278  XXXXXXXXXXXXXXXXDLRHRLAAYNFDSSPDRSEDMETEQPQMPTKKKEPNRRTAAQKK 99
                            +L+ RLAAYN +SSPDR  DME+E PQ+P +KKEP +R AAQKK
Sbjct: 1255 KPAVILDDDDDDDEVLELKERLAAYNLESSPDRPADMESEAPQVPVQKKEPTKRAAAQKK 1314

Query: 98   P---LSTVSE 78
                L+T+S+
Sbjct: 1315 ASVNLTTISD 1324


>ref|XP_015881653.1| PREDICTED: DNA topoisomerase 2 isoform X1 [Ziziphus jujuba]
          Length = 1487

 Score =  926 bits (2393), Expect = 0.0
 Identities = 478/731 (65%), Positives = 569/731 (77%), Gaps = 9/731 (1%)
 Frame = -3

Query: 2243 TWKQNQGTDVKNWTIKYYKGLGTSTDQEAKEYFEALGRHKKDFVWVDEQDGDAIELAFSK 2064
            +W+++   +   W+IKYYKGLGTST +E +EYF+ L +H+KDF+WVD+QDG AIELAFSK
Sbjct: 600  SWRESLRGNASGWSIKYYKGLGTSTSKEGREYFQNLDKHRKDFLWVDDQDGAAIELAFSK 659

Query: 2063 KKIEARKNWLRQFEPGTYLCDLEEHIKYRDFVHKELILFSIADLQRSIPSMVDGLKPGQR 1884
            KKIE RKNWLRQFEPGT+L   E+ IKY DFVHKELILFS+ADLQRSIPSMVDGLKPGQR
Sbjct: 660  KKIEERKNWLRQFEPGTHLDQKEKLIKYSDFVHKELILFSVADLQRSIPSMVDGLKPGQR 719

Query: 1883 KILFCSFKRNFIKEAKVAQFSGYVSEHSAYHHGEQSLASTIIGMAQDYVGSNNINLLLPN 1704
            KILFCSFKRNF KEAKVAQFSGYVSEHSAYHHGEQSLASTIIGMAQDYVGSNNINLL PN
Sbjct: 720  KILFCSFKRNFFKEAKVAQFSGYVSEHSAYHHGEQSLASTIIGMAQDYVGSNNINLLQPN 779

Query: 1703 GQFGTRGQGGKDHASARYIYTQLSSITRFLFPKADDFLLNYLNEDGQSIEPTWYVPTIPM 1524
            GQFGTR  GGKDHASARYI+T+LS ITRFLFPK DD LL+YLNEDGQ+IEPTWYVP IP 
Sbjct: 780  GQFGTRNLGGKDHASARYIFTRLSPITRFLFPKDDDKLLDYLNEDGQTIEPTWYVPIIPT 839

Query: 1523 VLVNGSEGIGTGWSTFIPNYNPLDIIANVRHLLNDEPMEPMHPWYKGFIGLIEKTATKEA 1344
            VLVNGSEGIGTGWS++IPNYNP DI+AN+R LLN   M PM PWY+GF G IEKT  KEA
Sbjct: 840  VLVNGSEGIGTGWSSYIPNYNPRDIVANIRRLLNGHSMVPMDPWYRGFKGTIEKT-VKEA 898

Query: 1343 GNSYTVSGIIEEVDETSLRITELPIRKWTQDYKEFLESVSAENDKSKDPFIEGCRDNSGG 1164
            G SYT+SGI+EEV+ET++RITELPIRKWTQDYKEFLES+S  NDK+KDPFIEG   +S  
Sbjct: 899  GVSYTISGILEEVNETTIRITELPIRKWTQDYKEFLESISQGNDKAKDPFIEGFTQHSDH 958

Query: 1163 EIVHFSVYMSPNNLSEAKQEGLMKKFKLTTSISTSNMHLFDSKGVIKKYDTPEQIIEEFF 984
              V   V+M   NL  AKQEGL+KKFKLTT+ISTSNMHLFD+KGVIKKYDTPEQI+EEFF
Sbjct: 959  ITVDILVHMPEENLVAAKQEGLLKKFKLTTTISTSNMHLFDAKGVIKKYDTPEQILEEFF 1018

Query: 983  HIRLEFYDKRKKALLANLENDMLKCDNKYRFIRGVVDGSIIVSNRKRADLFLELKEKGFT 804
            H+RLEFY+KRK+ LL NLE ++LK +NK RFI GVV+  IIVSNRKRADLFLEL++KGFT
Sbjct: 1019 HLRLEFYEKRKQVLLDNLEMELLKLENKVRFILGVVNEEIIVSNRKRADLFLELQQKGFT 1078

Query: 803  PFPKKKTAAEIAIAGSTDDADESEENNDVAIGKGVSASDYDYLLSLAIGTLTAEKMKELR 624
            PFPKK  + E  +AG+TD  +E+E+N++     GV  SDY+YLLS+AIGTLT EK++ L 
Sbjct: 1079 PFPKKAKSVEPEVAGATDYTEETEDNSN---PDGVRISDYEYLLSMAIGTLTLEKVQALC 1135

Query: 623  DERDKLMQEVEELKRATVKSLWMHDLDALESKFIEELNKSEKKWAENRQRI---LGEAKG 453
             ERDKL  EV++L++AT KSLW  DLDAL+ K ++EL+K++ +  + R+++   L  A  
Sbjct: 1136 AERDKLNGEVDDLRKATPKSLWEKDLDALD-KELDELDKNDAQAEDARKKLKSQLNPAAV 1194

Query: 452  TR--PVQTKPRKNTKKASNKESVVEQMEVSDNTVTETDKVGE-VXXXXXXXXXXXXXXXX 282
            T+       PRKN KKA+N E+VVE ME + ++  E +K  E V                
Sbjct: 1195 TKFAKAPKNPRKNNKKANNAEAVVEMMETTSSSTMEMEKAPEVVKPKGRAVSRKAPTKKQ 1254

Query: 281  XXXXXXXXXXXXXXXXXDLRHRLAAYNFDSSPDRSEDMETEQPQMPTKKKEPNRRTAAQK 102
                             +L+ RLAAYN +SSPDR  DME+E PQ+P +KKEP +R AAQK
Sbjct: 1255 EKPAVILDDDDDDDEVLELKERLAAYNLESSPDRPADMESEAPQVPVQKKEPTKRAAAQK 1314

Query: 101  KP---LSTVSE 78
            K    L+T+S+
Sbjct: 1315 KASVNLTTISD 1325


>gb|EOY18138.1| DNA topoisomerase 2 isoform 2 [Theobroma cacao]
          Length = 1285

 Score =  924 bits (2388), Expect = 0.0
 Identities = 471/724 (65%), Positives = 562/724 (77%), Gaps = 3/724 (0%)
 Frame = -3

Query: 2240 WKQNQGTDVKNWTIKYYKGLGTSTDQEAKEYFEALGRHKKDFVWVDEQDGDAIELAFSKK 2061
            WK++ G + K W+IKYYKGLGTST +E K+YF+ L +H+K+FVW DEQDG+AIELAFSKK
Sbjct: 400  WKESLGGNAKGWSIKYYKGLGTSTSKEGKDYFKNLDKHRKEFVWQDEQDGEAIELAFSKK 459

Query: 2060 KIEARKNWLRQFEPGTYLCDLEEHIKYRDFVHKELILFSIADLQRSIPSMVDGLKPGQRK 1881
            KIEARKNWLRQFEPGT+L   ++ IKY +F++KELILFS+ADLQRSIPSM+DGLKPGQRK
Sbjct: 460  KIEARKNWLRQFEPGTHLDQSQKLIKYSEFINKELILFSMADLQRSIPSMIDGLKPGQRK 519

Query: 1880 ILFCSFKRNFIKEAKVAQFSGYVSEHSAYHHGEQSLASTIIGMAQDYVGSNNINLLLPNG 1701
            ILFCSFKRNF+KEAKVAQFSGYVSEHSAYHHGEQSLASTI+GMAQD+VGSNNINLL P G
Sbjct: 520  ILFCSFKRNFVKEAKVAQFSGYVSEHSAYHHGEQSLASTIVGMAQDFVGSNNINLLNPGG 579

Query: 1700 QFGTRGQGGKDHASARYIYTQLSSITRFLFPKADDFLLNYLNEDGQSIEPTWYVPTIPMV 1521
            QFGTR QGGKD ASARYI+T LS ITR+LFPK DD LL+YLNEDGQSIEP WYVP IPMV
Sbjct: 580  QFGTRNQGGKDAASARYIFTNLSPITRYLFPKDDDGLLDYLNEDGQSIEPIWYVPIIPMV 639

Query: 1520 LVNGSEGIGTGWSTFIPNYNPLDIIANVRHLLNDEPMEPMHPWYKGFIGLIEKTATKEAG 1341
            LVNGSEGIGTGWS++IPNYNP DI+ANVR LLN E MEPMHPWY+GF G IEKTA+KEAG
Sbjct: 640  LVNGSEGIGTGWSSYIPNYNPRDIVANVRRLLNGEQMEPMHPWYRGFKGNIEKTASKEAG 699

Query: 1340 NSYTVSGIIEEVDETSLRITELPIRKWTQDYKEFLESVSAENDKSKDPFIEGCRDNSGGE 1161
             +YT++GIIEEVDET+LRITELP+R+WTQDY+EFLES+   N    DPFI+  R  S   
Sbjct: 700  VTYTITGIIEEVDETTLRITELPVRRWTQDYREFLESIITGN----DPFIKEFRQYSDDT 755

Query: 1160 IVHFSVYMSPNNLSEAKQEGLMKKFKLTTSISTSNMHLFDSKGVIKKYDTPEQIIEEFFH 981
             V F V ++  N+  AKQEGL+KKFKLTT+ISTSNMHLFDSKG+IKKYDTPEQI+EEFFH
Sbjct: 756  TVEFEVILTEENMMVAKQEGLLKKFKLTTTISTSNMHLFDSKGMIKKYDTPEQILEEFFH 815

Query: 980  IRLEFYDKRKKALLANLENDMLKCDNKYRFIRGVVDGSIIVSNRKRADLFLELKEKGFTP 801
            +R EFY+KRKK LL NLE ++LK +NK RFI GVV G IIV+NRKRADLFLEL+ KGFTP
Sbjct: 816  LRFEFYEKRKKLLLDNLEMELLKMENKVRFILGVVKGEIIVNNRKRADLFLELQTKGFTP 875

Query: 800  FPKKKTAAEIAIAGSTDDADESEENNDVAIGKGVSASDYDYLLSLAIGTLTAEKMKELRD 621
            FPKK    E+A+AG+TDD +E+EEN++V+  KG+ ASDYDYLLS+AIG+LT EK++EL  
Sbjct: 876  FPKKAKTVEVAVAGATDDTEETEENSEVS-AKGLQASDYDYLLSMAIGSLTLEKVQELCA 934

Query: 620  ERDKLMQEVEELKRATVKSLWMHDLDALESKFIEELNKSEKKWAENRQRILGEA--KGTR 447
            +RDKL QEVE+L++AT KSLW+ DLD LE +  E+   ++ + A    +  GEA  +  R
Sbjct: 935  DRDKLQQEVEDLRKATPKSLWLKDLDNLEIQLDEQDKAAQAEEAAKLVKGRGEAGKRAQR 994

Query: 446  PVQTKPRKNTKKASNKESVVEQMEVSDNTVTETDKVGEVXXXXXXXXXXXXXXXXXXXXX 267
                 PRK  KK  N E+V E  ++S ++  ET +                         
Sbjct: 995  QAPKIPRKINKKEKNAETVTETTDISSSSAMETAETAPA----AVKPKGRGGSRKAKKDD 1050

Query: 266  XXXXXXXXXXXXDLRHRLAAYNFDSSPDRSEDMETEQPQMPTKKKEPNRR-TAAQKKPLS 90
                        DLR RLA YN DSSPD S  METE PQ+P  KKEP++R  AA+KKP +
Sbjct: 1051 SDDDDDEDFGIPDLRERLAKYNLDSSPDHSAAMETEVPQVPAGKKEPSKRAAAARKKPAT 1110

Query: 89   TVSE 78
            ++SE
Sbjct: 1111 SLSE 1114


>gb|EOY18137.1| DNA topoisomerase 2 isoform 1 [Theobroma cacao]
          Length = 1473

 Score =  924 bits (2388), Expect = 0.0
 Identities = 471/724 (65%), Positives = 562/724 (77%), Gaps = 3/724 (0%)
 Frame = -3

Query: 2240 WKQNQGTDVKNWTIKYYKGLGTSTDQEAKEYFEALGRHKKDFVWVDEQDGDAIELAFSKK 2061
            WK++ G + K W+IKYYKGLGTST +E K+YF+ L +H+K+FVW DEQDG+AIELAFSKK
Sbjct: 589  WKESLGGNAKGWSIKYYKGLGTSTSKEGKDYFKNLDKHRKEFVWQDEQDGEAIELAFSKK 648

Query: 2060 KIEARKNWLRQFEPGTYLCDLEEHIKYRDFVHKELILFSIADLQRSIPSMVDGLKPGQRK 1881
            KIEARKNWLRQFEPGT+L   ++ IKY +F++KELILFS+ADLQRSIPSM+DGLKPGQRK
Sbjct: 649  KIEARKNWLRQFEPGTHLDQSQKLIKYSEFINKELILFSMADLQRSIPSMIDGLKPGQRK 708

Query: 1880 ILFCSFKRNFIKEAKVAQFSGYVSEHSAYHHGEQSLASTIIGMAQDYVGSNNINLLLPNG 1701
            ILFCSFKRNF+KEAKVAQFSGYVSEHSAYHHGEQSLASTI+GMAQD+VGSNNINLL P G
Sbjct: 709  ILFCSFKRNFVKEAKVAQFSGYVSEHSAYHHGEQSLASTIVGMAQDFVGSNNINLLNPGG 768

Query: 1700 QFGTRGQGGKDHASARYIYTQLSSITRFLFPKADDFLLNYLNEDGQSIEPTWYVPTIPMV 1521
            QFGTR QGGKD ASARYI+T LS ITR+LFPK DD LL+YLNEDGQSIEP WYVP IPMV
Sbjct: 769  QFGTRNQGGKDAASARYIFTNLSPITRYLFPKDDDGLLDYLNEDGQSIEPIWYVPIIPMV 828

Query: 1520 LVNGSEGIGTGWSTFIPNYNPLDIIANVRHLLNDEPMEPMHPWYKGFIGLIEKTATKEAG 1341
            LVNGSEGIGTGWS++IPNYNP DI+ANVR LLN E MEPMHPWY+GF G IEKTA+KEAG
Sbjct: 829  LVNGSEGIGTGWSSYIPNYNPRDIVANVRRLLNGEQMEPMHPWYRGFKGNIEKTASKEAG 888

Query: 1340 NSYTVSGIIEEVDETSLRITELPIRKWTQDYKEFLESVSAENDKSKDPFIEGCRDNSGGE 1161
             +YT++GIIEEVDET+LRITELP+R+WTQDY+EFLES+   N    DPFI+  R  S   
Sbjct: 889  VTYTITGIIEEVDETTLRITELPVRRWTQDYREFLESIITGN----DPFIKEFRQYSDDT 944

Query: 1160 IVHFSVYMSPNNLSEAKQEGLMKKFKLTTSISTSNMHLFDSKGVIKKYDTPEQIIEEFFH 981
             V F V ++  N+  AKQEGL+KKFKLTT+ISTSNMHLFDSKG+IKKYDTPEQI+EEFFH
Sbjct: 945  TVEFEVILTEENMMVAKQEGLLKKFKLTTTISTSNMHLFDSKGMIKKYDTPEQILEEFFH 1004

Query: 980  IRLEFYDKRKKALLANLENDMLKCDNKYRFIRGVVDGSIIVSNRKRADLFLELKEKGFTP 801
            +R EFY+KRKK LL NLE ++LK +NK RFI GVV G IIV+NRKRADLFLEL+ KGFTP
Sbjct: 1005 LRFEFYEKRKKLLLDNLEMELLKMENKVRFILGVVKGEIIVNNRKRADLFLELQTKGFTP 1064

Query: 800  FPKKKTAAEIAIAGSTDDADESEENNDVAIGKGVSASDYDYLLSLAIGTLTAEKMKELRD 621
            FPKK    E+A+AG+TDD +E+EEN++V+  KG+ ASDYDYLLS+AIG+LT EK++EL  
Sbjct: 1065 FPKKAKTVEVAVAGATDDTEETEENSEVS-AKGLQASDYDYLLSMAIGSLTLEKVQELCA 1123

Query: 620  ERDKLMQEVEELKRATVKSLWMHDLDALESKFIEELNKSEKKWAENRQRILGEA--KGTR 447
            +RDKL QEVE+L++AT KSLW+ DLD LE +  E+   ++ + A    +  GEA  +  R
Sbjct: 1124 DRDKLQQEVEDLRKATPKSLWLKDLDNLEIQLDEQDKAAQAEEAAKLVKGRGEAGKRAQR 1183

Query: 446  PVQTKPRKNTKKASNKESVVEQMEVSDNTVTETDKVGEVXXXXXXXXXXXXXXXXXXXXX 267
                 PRK  KK  N E+V E  ++S ++  ET+                          
Sbjct: 1184 QAPKIPRKINKKEKNAETVTETTDISSSSAMETETA-----PAAVKPKGRGGSRKAKKDD 1238

Query: 266  XXXXXXXXXXXXDLRHRLAAYNFDSSPDRSEDMETEQPQMPTKKKEPNRR-TAAQKKPLS 90
                        DLR RLA YN DSSPD S  METE PQ+P  KKEP++R  AA+KKP +
Sbjct: 1239 SDDDDDEDFGIPDLRERLAKYNLDSSPDHSAAMETEVPQVPAGKKEPSKRAAAARKKPAT 1298

Query: 89   TVSE 78
            ++SE
Sbjct: 1299 SLSE 1302


>ref|XP_007009327.2| PREDICTED: DNA topoisomerase 2 [Theobroma cacao]
          Length = 1473

 Score =  921 bits (2380), Expect = 0.0
 Identities = 470/724 (64%), Positives = 560/724 (77%), Gaps = 3/724 (0%)
 Frame = -3

Query: 2240 WKQNQGTDVKNWTIKYYKGLGTSTDQEAKEYFEALGRHKKDFVWVDEQDGDAIELAFSKK 2061
            WK++ G + K W+IKYYKGLGTST +E K+YF+ L +H+K+FVW DEQDG+AIELAFSKK
Sbjct: 589  WKESLGGNAKGWSIKYYKGLGTSTSKEGKDYFKNLDKHRKEFVWQDEQDGEAIELAFSKK 648

Query: 2060 KIEARKNWLRQFEPGTYLCDLEEHIKYRDFVHKELILFSIADLQRSIPSMVDGLKPGQRK 1881
            KIEARKNWLRQFEPGT+L   ++ IKY +F++KELILFS+ADLQRSIPSM+DGLKPGQRK
Sbjct: 649  KIEARKNWLRQFEPGTHLDQSQKLIKYSEFINKELILFSMADLQRSIPSMIDGLKPGQRK 708

Query: 1880 ILFCSFKRNFIKEAKVAQFSGYVSEHSAYHHGEQSLASTIIGMAQDYVGSNNINLLLPNG 1701
            ILFCSFKRNF+KEAKVAQFSGYVSEHSAYHHGEQSLASTI+GMAQD+VGSNNINLL P G
Sbjct: 709  ILFCSFKRNFVKEAKVAQFSGYVSEHSAYHHGEQSLASTIVGMAQDFVGSNNINLLHPGG 768

Query: 1700 QFGTRGQGGKDHASARYIYTQLSSITRFLFPKADDFLLNYLNEDGQSIEPTWYVPTIPMV 1521
            QFGTR QGGKD ASARYI+T LS ITR+LFPK DD LL+YLNEDGQSIEP WYVP IPMV
Sbjct: 769  QFGTRNQGGKDAASARYIFTNLSPITRYLFPKDDDGLLDYLNEDGQSIEPIWYVPIIPMV 828

Query: 1520 LVNGSEGIGTGWSTFIPNYNPLDIIANVRHLLNDEPMEPMHPWYKGFIGLIEKTATKEAG 1341
            LVNGSEGIGTGWS++IPNYNP DI+ANVR LLN E MEPMHPWY+GF G IEKTA+KEAG
Sbjct: 829  LVNGSEGIGTGWSSYIPNYNPRDIVANVRRLLNGEQMEPMHPWYRGFKGNIEKTASKEAG 888

Query: 1340 NSYTVSGIIEEVDETSLRITELPIRKWTQDYKEFLESVSAENDKSKDPFIEGCRDNSGGE 1161
             +YT++GIIEEVDET+LRITELP+R+WTQDY+EFLES+   N    DPFI+  R  S   
Sbjct: 889  VTYTITGIIEEVDETTLRITELPVRRWTQDYREFLESIITGN----DPFIKEFRQYSDDT 944

Query: 1160 IVHFSVYMSPNNLSEAKQEGLMKKFKLTTSISTSNMHLFDSKGVIKKYDTPEQIIEEFFH 981
             V F V ++  N+  AKQEGL+KKFKLTT+ISTSNMHLFDSKG+IKKYD PEQI+EEFFH
Sbjct: 945  TVEFEVILTEENMMMAKQEGLLKKFKLTTTISTSNMHLFDSKGMIKKYDAPEQILEEFFH 1004

Query: 980  IRLEFYDKRKKALLANLENDMLKCDNKYRFIRGVVDGSIIVSNRKRADLFLELKEKGFTP 801
            +R EFY+KRKK LL NLE ++LK +NK RFI GVV G IIV+NRKRADLFLEL+ KGFTP
Sbjct: 1005 LRFEFYEKRKKLLLDNLEMELLKMENKVRFILGVVKGEIIVNNRKRADLFLELQTKGFTP 1064

Query: 800  FPKKKTAAEIAIAGSTDDADESEENNDVAIGKGVSASDYDYLLSLAIGTLTAEKMKELRD 621
            FPKK    E+A+AG+TDD +E+EEN++V+  KGV ASDYDYLLS+AIG+LT EK++EL  
Sbjct: 1065 FPKKAKTVEVAVAGATDDTEETEENSEVS-AKGVQASDYDYLLSMAIGSLTLEKVQELCA 1123

Query: 620  ERDKLMQEVEELKRATVKSLWMHDLDALESKFIEELNKSEKKWAENRQRILGEA--KGTR 447
            +RDKL QEVE+L++AT  SLW+ DLD LE +  E+   ++ + A    +  GEA  +  R
Sbjct: 1124 DRDKLQQEVEDLRKATPMSLWLKDLDNLEIQLDEQDKAAQAEEAAKLVKGRGEAGKRAQR 1183

Query: 446  PVQTKPRKNTKKASNKESVVEQMEVSDNTVTETDKVGEVXXXXXXXXXXXXXXXXXXXXX 267
                 PRK  KK  N E+V E  ++S ++  ET+                          
Sbjct: 1184 QAPKIPRKINKKEKNAETVTETTDISSSSAMETETA-----PAAVKPKGRGGSRKAKKDD 1238

Query: 266  XXXXXXXXXXXXDLRHRLAAYNFDSSPDRSEDMETEQPQMPTKKKEPNRR-TAAQKKPLS 90
                        DLR RLA YN DSSPD S  METE PQ+P  KKEP++R  AA+KKP +
Sbjct: 1239 SDDDDDEDFGIPDLRERLAKYNLDSSPDHSAAMETEVPQVPAGKKEPSKRAAAARKKPAT 1298

Query: 89   TVSE 78
            ++SE
Sbjct: 1299 SLSE 1302


>ref|XP_008231458.1| PREDICTED: DNA topoisomerase 2 isoform X2 [Prunus mume]
          Length = 1470

 Score =  915 bits (2366), Expect = 0.0
 Identities = 463/714 (64%), Positives = 547/714 (76%), Gaps = 6/714 (0%)
 Frame = -3

Query: 2240 WKQNQGTDVKNWTIKYYKGLGTSTDQEAKEYFEALGRHKKDFVWVDEQDGDAIELAFSKK 2061
            WK++   +   W+IKYYKGLGTST +E ++YF+ L  HKKDF+W+DE+DG+AIELAFSKK
Sbjct: 595  WKESLRGNASGWSIKYYKGLGTSTSKEGRDYFQNLAMHKKDFIWIDERDGEAIELAFSKK 654

Query: 2060 KIEARKNWLRQFEPGTYLCDLEEHIKYRDFVHKELILFSIADLQRSIPSMVDGLKPGQRK 1881
            KIE RKNWLRQFEP  +L   E+ IKY DFVHKELI FS+ADLQRSIPSMVDGLKPGQRK
Sbjct: 655  KIEERKNWLRQFEPSVHLDQKEKLIKYSDFVHKELIQFSMADLQRSIPSMVDGLKPGQRK 714

Query: 1880 ILFCSFKRNFIKEAKVAQFSGYVSEHSAYHHGEQSLASTIIGMAQDYVGSNNINLLLPNG 1701
            ILFCSFKRNF+KEAKVAQFSGYVSEHSAYHHGEQSLASTIIGMAQDYVGSNNINLL PNG
Sbjct: 715  ILFCSFKRNFVKEAKVAQFSGYVSEHSAYHHGEQSLASTIIGMAQDYVGSNNINLLQPNG 774

Query: 1700 QFGTRGQGGKDHASARYIYTQLSSITRFLFPKADDFLLNYLNEDGQSIEPTWYVPTIPMV 1521
            QFGTR  GGKDHASARYIYT+LS ITRFLFPK DD LL+YLNEDGQSIEPTWYVP IP V
Sbjct: 775  QFGTRNLGGKDHASARYIYTRLSPITRFLFPKDDDRLLDYLNEDGQSIEPTWYVPIIPTV 834

Query: 1520 LVNGSEGIGTGWSTFIPNYNPLDIIANVRHLLNDEPMEPMHPWYKGFIGLIEKTATKEAG 1341
            LVNGSEGIGTGWS++IPNYNP DI+ANVR LLN E M PM PWY+GF G IEKT  KE+G
Sbjct: 835  LVNGSEGIGTGWSSYIPNYNPRDIVANVRRLLNGEAMVPMDPWYRGFAGTIEKT-VKESG 893

Query: 1340 NSYTVSGIIEEVDETSLRITELPIRKWTQDYKEFLESVSAENDKSKDPFIEGCRDNSGGE 1161
             SYTV G+IEE +ET++RI+ELPIR+WTQDYKEFLES+S  NDK+KDPFIEG   +S   
Sbjct: 894  VSYTVCGVIEEGNETTVRISELPIRRWTQDYKEFLESISQGNDKAKDPFIEGFTQHSDHS 953

Query: 1160 IVHFSVYMSPNNLSEAKQEGLMKKFKLTTSISTSNMHLFDSKGVIKKYDTPEQIIEEFFH 981
             V   V++   NL  A+QEGL+KKFKLTTSISTSNMHLFD KGVIKKYDTPEQI+EEFFH
Sbjct: 954  TVDIIVHLPEENLMAARQEGLLKKFKLTTSISTSNMHLFDPKGVIKKYDTPEQILEEFFH 1013

Query: 980  IRLEFYDKRKKALLANLENDMLKCDNKYRFIRGVVDGSIIVSNRKRADLFLELKEKGFTP 801
            +RLEFY+KRKK LL NLE ++LK +NK RFI  VV+G IIVSNR+RADLFLEL++KGFTP
Sbjct: 1014 LRLEFYEKRKKVLLDNLEMELLKLENKVRFILAVVNGEIIVSNRRRADLFLELQQKGFTP 1073

Query: 800  FPKKKTAAEIAIAGSTDDADESEENNDVAIGKGVSASDYDYLLSLAIGTLTAEKMKELRD 621
            FPKK  A E  +AG+ +D +E+EEN++ A G G   SDY+YL+S+AIGTLT E+++ L  
Sbjct: 1074 FPKKTKAQEPEVAGAIEDTEETEENSESASGNGARISDYEYLISMAIGTLTIERVQALCA 1133

Query: 620  ERDKLMQEVEELKRATVKSLWMHDLDALESKFIEELNKSE------KKWAENRQRILGEA 459
            +RDK+  EV EL+ +T +SLW+ DLDALE + + EL KSE      KK + N+ +    A
Sbjct: 1134 DRDKVNNEVAELRNSTPRSLWLKDLDALEME-LGELEKSEALAEEAKKKSRNQVKNAPAA 1192

Query: 458  KGTRPVQTKPRKNTKKASNKESVVEQMEVSDNTVTETDKVGEVXXXXXXXXXXXXXXXXX 279
            K ++P    PRKN KKA+N E+  E  E S + V E +K  E+                 
Sbjct: 1193 KVSKPAPKNPRKNNKKANNAEAAAESRETSSSFVFEMEKAPEIVKRKVGAVAKKAPAGKK 1252

Query: 278  XXXXXXXXXXXXXXXXDLRHRLAAYNFDSSPDRSEDMETEQPQMPTKKKEPNRR 117
                            +L+ RLAAYN DSSP+ S   ETE PQ P ++KEP++R
Sbjct: 1253 QAKSAVVLSDDDDEVLELKDRLAAYNLDSSPENSAGKETEVPQEPVQRKEPSKR 1306


>ref|XP_010023678.1| PREDICTED: DNA topoisomerase 2 [Eucalyptus grandis]
 gb|KCW60013.1| hypothetical protein EUGRSUZ_H02748 [Eucalyptus grandis]
          Length = 1496

 Score =  916 bits (2367), Expect = 0.0
 Identities = 473/728 (64%), Positives = 558/728 (76%), Gaps = 6/728 (0%)
 Frame = -3

Query: 2243 TWKQNQGTDVKNWTIKYYKGLGTSTDQEAKEYFEALGRHKKDFVWVDEQDGDAIELAFSK 2064
            +WK++ G     W+IKYYKGLGTST +E K+YF+ L  HKKDFVWVD+QDGDAIELAFSK
Sbjct: 608  SWKESLGGSGSGWSIKYYKGLGTSTSKEGKQYFQNLDMHKKDFVWVDDQDGDAIELAFSK 667

Query: 2063 KKIEARKNWLRQFEPGTYLCDLEEHIKYRDFVHKELILFSIADLQRSIPSMVDGLKPGQR 1884
            KKIEARK WLRQFEPGTYL   E+ IKY DFV+KELILFS+ADLQRSIPSMVDGLKPGQR
Sbjct: 668  KKIEARKTWLRQFEPGTYLDQKEKLIKYSDFVNKELILFSMADLQRSIPSMVDGLKPGQR 727

Query: 1883 KILFCSFKRNFIKEAKVAQFSGYVSEHSAYHHGEQSLASTIIGMAQDYVGSNNINLLLPN 1704
            KILFCSFKRNFIKEAKVAQFSGYVSEHSAYHHGEQSLASTIIGMAQDYVGSNNINLL+PN
Sbjct: 728  KILFCSFKRNFIKEAKVAQFSGYVSEHSAYHHGEQSLASTIIGMAQDYVGSNNINLLMPN 787

Query: 1703 GQFGTRGQGGKDHASARYIYTQLSSITRFLFPKADDFLLNYLNEDGQSIEPTWYVPTIPM 1524
            GQFGTR  GGKDHAS RY+YT+LS  TRFLFPK DD LL+YLNEDGQSIEPTWY+P +PM
Sbjct: 788  GQFGTRNMGGKDHASPRYVYTKLSPTTRFLFPKDDDNLLSYLNEDGQSIEPTWYMPILPM 847

Query: 1523 VLVNGSEGIGTGWSTFIPNYNPLDIIANVRHLLNDEPMEPMHPWYKGFIGLIEKTATKEA 1344
            VLVNGSEGIGTGWS++IPNYNP DIIAN+R LLN E MEPM PWY+GF G IEKTATKEA
Sbjct: 848  VLVNGSEGIGTGWSSYIPNYNPRDIIANLRRLLNGEMMEPMDPWYRGFRGTIEKTATKEA 907

Query: 1343 GNSYTVSGIIEEVDETSLRITELPIRKWTQDYKEFLESVS-AENDKSKDPFIEGCRDNSG 1167
            G +YTV GIIEEVD+T+LRITELPIR+WTQDY+EFLES+S  E DK+KDPF++  R  S 
Sbjct: 908  GVTYTVCGIIEEVDDTTLRITELPIRRWTQDYREFLESLSTGEKDKAKDPFVKEFRQYSD 967

Query: 1166 GEIVHFSVYMSPNNLSEAKQEGLMKKFKLTTSISTSNMHLFDSKGVIKKYDTPEQIIEEF 987
               VHF V ++  N+  AKQEGL+KKFKLT+SISTSNMHLFD  GVIKKYD+PEQI+EEF
Sbjct: 968  DVTVHFEVMLTEENMMIAKQEGLLKKFKLTSSISTSNMHLFDPNGVIKKYDSPEQILEEF 1027

Query: 986  FHIRLEFYDKRKKALLANLENDMLKCDNKYRFIRGVVDGSIIVSNRKRADLFLELKEKGF 807
            FH+RLE Y+KRKK LL NLE  ++  DNK RFI GVV G IIVSNRKRADLF EL+ KGF
Sbjct: 1028 FHLRLECYEKRKKILLENLELKLVMLDNKVRFILGVVHGEIIVSNRKRADLFQELQAKGF 1087

Query: 806  TPFPKKKTAAEIAIAGSTDDADESEENNDVAIGKGVSASDYDYLLSLAIGTLTAEKMKEL 627
            TPF K+    E A+AGSTDDA+E+EEN++    KGV ASDY+YLLS+AIG LT EK++EL
Sbjct: 1088 TPFRKETKTIETAVAGSTDDAEETEENSEPTT-KGVKASDYEYLLSMAIGALTLEKVQEL 1146

Query: 626  RDERDKLMQEVEELKRATVKSLWMHDLDALESKFIEELNKSEKKWAENRQRILGEAKG-- 453
              ++DKL+ EV+ L++AT ++LW+ DL ALE K ++E  K + + AE  ++   +A G  
Sbjct: 1147 CADKDKLVDEVDALRKATPENLWLEDLAALEEK-LDEQEKMDAQ-AEETRKARSKANGVG 1204

Query: 452  ---TRPVQTKPRKNTKKASNKESVVEQMEVSDNTVTETDKVGEVXXXXXXXXXXXXXXXX 282
               +R    KPRKN  KA+N E+  E  + S  T+ E     +V                
Sbjct: 1205 TKVSRQAPKKPRKNDTKANNPEAQAEVTQGSTVTL-EAGNAADVAKPKRGAGARKAPAPK 1263

Query: 281  XXXXXXXXXXXXXXXXXDLRHRLAAYNFDSSPDRSEDMETEQPQMPTKKKEPNRRTAAQK 102
                             DL+ RLAAYN +SSPD S  +E + P++P K+KEP++R A +K
Sbjct: 1264 PSKSASVSDDDEDFEMLDLKERLAAYNLESSPDNSSALEDKVPEIPVKEKEPSKRAATRK 1323

Query: 101  KPLSTVSE 78
            KP   +SE
Sbjct: 1324 KPSVILSE 1331