BLASTX 2.2.26 [Sep-21-2011]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= Rehmannia29_contig00017266
         (1936 letters)

Database: All non-redundant GenBank CDS
translations+PDB+SwissProt+PIR+PRF excluding environmental samples
from WGS projects 
           149,584,005 sequences; 54,822,741,787 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

ref|XP_011074562.1| putative bifunctional dihydrofolate reductas...  1017   0.0  
ref|XP_011074564.1| putative bifunctional dihydrofolate reductas...   987   0.0  
ref|XP_012843023.1| PREDICTED: bifunctional dihydrofolate reduct...   982   0.0  
ref|XP_020548650.1| putative bifunctional dihydrofolate reductas...   980   0.0  
ref|XP_012843024.1| PREDICTED: bifunctional dihydrofolate reduct...   931   0.0  
ref|XP_022884764.1| putative bifunctional dihydrofolate reductas...   894   0.0  
ref|XP_010254750.1| PREDICTED: putative bifunctional dihydrofola...   872   0.0  
ref|XP_010254749.1| PREDICTED: putative bifunctional dihydrofola...   872   0.0  
ref|XP_010254751.1| PREDICTED: putative bifunctional dihydrofola...   864   0.0  
ref|XP_021653888.1| bifunctional dihydrofolate reductase-thymidy...   858   0.0  
ref|XP_021662680.1| bifunctional dihydrofolate reductase-thymidy...   858   0.0  
gb|OVA18766.1| Thymidylate synthase [Macleaya cordata]                859   0.0  
ref|XP_021658747.1| bifunctional dihydrofolate reductase-thymidy...   856   0.0  
ref|XP_010664716.1| PREDICTED: putative bifunctional dihydrofola...   852   0.0  
ref|XP_021628142.1| bifunctional dihydrofolate reductase-thymidy...   849   0.0  
ref|XP_020533467.1| bifunctional dihydrofolate reductase-thymidy...   849   0.0  
ref|XP_004289633.1| PREDICTED: bifunctional dihydrofolate reduct...   848   0.0  
ref|XP_010664720.1| PREDICTED: putative bifunctional dihydrofola...   848   0.0  
ref|XP_024166629.1| bifunctional dihydrofolate reductase-thymidy...   845   0.0  
ref|XP_011037491.1| PREDICTED: bifunctional dihydrofolate reduct...   845   0.0  

>ref|XP_011074562.1| putative bifunctional dihydrofolate reductase-thymidylate synthase
            isoform X1 [Sesamum indicum]
 ref|XP_011074563.1| putative bifunctional dihydrofolate reductase-thymidylate synthase
            isoform X1 [Sesamum indicum]
          Length = 584

 Score = 1017 bits (2630), Expect = 0.0
 Identities = 496/568 (87%), Positives = 522/568 (91%), Gaps = 1/568 (0%)
 Frame = -1

Query: 1936 VVLGSFLRGIFGLSSVSSFVCSFETLKPFVAQRFCRRYLVMGGDSIEFFSNGNTNTQPIP 1757
            V LGSF   I      SS   + ETLK F  QRFCRRYLVMGGD+IE FSNGNT T+PI 
Sbjct: 18   VTLGSFGSNILSAWG-SSLPQAPETLKAFNTQRFCRRYLVMGGDAIECFSNGNTTTEPIS 76

Query: 1756 QRTYQVVVAATPDMGIGKDGKLPWRLPGDLKFFKEITASTSDPNKKNVVMMGRKTWESIP 1577
            QRTYQVVVAATPDMGIGKDGKLPWRLPGDLKFFKEITA+TSDPNKKN VMMGR+TWESIP
Sbjct: 77   QRTYQVVVAATPDMGIGKDGKLPWRLPGDLKFFKEITATTSDPNKKNAVMMGRRTWESIP 136

Query: 1576 PQFRPLPGRLNVILTRSGSSDVPAAENVIFCGSLPSALKLLEEPPYSFSIEKVFLIGGGQ 1397
            PQFRPLPGRLNV+LTRS SSDV AAENVI C S+ SALKLL EPPYS S+EKVFLIGGGQ
Sbjct: 137  PQFRPLPGRLNVVLTRSASSDVAAAENVISCRSMSSALKLLAEPPYSLSVEKVFLIGGGQ 196

Query: 1396 ILREALNAPECDAIHITEIKTYIDCDTFIPPIDMSLYQPWYSSSLIEENGVPYCFVTYVR 1217
            ILREALNA ECDAIHITEIKT ++CDTFIPPIDMS+YQPWYSS+ +EENG+ YCF TYVR
Sbjct: 197  ILREALNAAECDAIHITEIKTSVECDTFIPPIDMSIYQPWYSSTPVEENGIQYCFATYVR 256

Query: 1216 LNTN-GGHLDSGHGISCNGSTSRPKGLKLSDFTFLPKFIFEKHEEFLYLRLVQDIISNGN 1040
            L T+  G ++SGH +SCNGSTSR K  KLSDFT+LPKFIFEKHEEF YLRLVQDIISNGN
Sbjct: 257  LRTSTSGPVNSGHELSCNGSTSRSKRPKLSDFTYLPKFIFEKHEEFQYLRLVQDIISNGN 316

Query: 1039 NKDDRTGTGTLSKFGCQMRFNLRKSFPLLTTKRVFWRGVVEELLWFISGSTNAKILQEKG 860
            +KDDRTGTGTLS FGCQM FNLRKSFPLLTTKRVFWRGVVEELLWFISGSTNAKILQEKG
Sbjct: 317  SKDDRTGTGTLSNFGCQMHFNLRKSFPLLTTKRVFWRGVVEELLWFISGSTNAKILQEKG 376

Query: 859  IHIWDGNASREFLDSIGLTDREEGDLGPVYGFQWRHFGARYTNMHADYTGQGFDQLLDVI 680
            IHIWDGNASREFLDSIGLTDREEGDLGP+YGFQWRHFGARYTNMHADYTGQGFDQLLDVI
Sbjct: 377  IHIWDGNASREFLDSIGLTDREEGDLGPIYGFQWRHFGARYTNMHADYTGQGFDQLLDVI 436

Query: 679  DKIKNKPDDRRIILSAWNPSDLKLMALPPCHMFAQFYVANGELSCQMYQRSADMGLGVPF 500
            DKIKNKPDDRRIILSAWNPSDLKLMALPPCHMFAQFYVANGELSCQMYQRSADMGLGVPF
Sbjct: 437  DKIKNKPDDRRIILSAWNPSDLKLMALPPCHMFAQFYVANGELSCQMYQRSADMGLGVPF 496

Query: 499  NIASYSLLTCMIAHVCGLVPGDFVHVIGDAHVYKTHVSPLQEQLKKLPRPFPILKINPHK 320
            NIASY+LLTCMIAHVCGL+PG+FVHVIGDAHVYKTH+SPLQEQLKKLPRPFPILKINP K
Sbjct: 497  NIASYALLTCMIAHVCGLIPGEFVHVIGDAHVYKTHISPLQEQLKKLPRPFPILKINPEK 556

Query: 319  KDIDSFVAADFELKNYEPHPKLEMKMAV 236
            KDIDSFVAADFEL+NYEPH KLEMKMAV
Sbjct: 557  KDIDSFVAADFELRNYEPHQKLEMKMAV 584


>ref|XP_011074564.1| putative bifunctional dihydrofolate reductase-thymidylate synthase
            isoform X3 [Sesamum indicum]
 ref|XP_011074566.1| putative bifunctional dihydrofolate reductase-thymidylate synthase
            isoform X3 [Sesamum indicum]
 ref|XP_020548651.1| putative bifunctional dihydrofolate reductase-thymidylate synthase
            isoform X3 [Sesamum indicum]
 ref|XP_020548652.1| putative bifunctional dihydrofolate reductase-thymidylate synthase
            isoform X3 [Sesamum indicum]
 ref|XP_020548653.1| putative bifunctional dihydrofolate reductase-thymidylate synthase
            isoform X3 [Sesamum indicum]
          Length = 528

 Score =  987 bits (2552), Expect = 0.0
 Identities = 474/528 (89%), Positives = 499/528 (94%), Gaps = 1/528 (0%)
 Frame = -1

Query: 1816 MGGDSIEFFSNGNTNTQPIPQRTYQVVVAATPDMGIGKDGKLPWRLPGDLKFFKEITAST 1637
            MGGD+IE FSNGNT T+PI QRTYQVVVAATPDMGIGKDGKLPWRLPGDLKFFKEITA+T
Sbjct: 1    MGGDAIECFSNGNTTTEPISQRTYQVVVAATPDMGIGKDGKLPWRLPGDLKFFKEITATT 60

Query: 1636 SDPNKKNVVMMGRKTWESIPPQFRPLPGRLNVILTRSGSSDVPAAENVIFCGSLPSALKL 1457
            SDPNKKN VMMGR+TWESIPPQFRPLPGRLNV+LTRS SSDV AAENVI C S+ SALKL
Sbjct: 61   SDPNKKNAVMMGRRTWESIPPQFRPLPGRLNVVLTRSASSDVAAAENVISCRSMSSALKL 120

Query: 1456 LEEPPYSFSIEKVFLIGGGQILREALNAPECDAIHITEIKTYIDCDTFIPPIDMSLYQPW 1277
            L EPPYS S+EKVFLIGGGQILREALNA ECDAIHITEIKT ++CDTFIPPIDMS+YQPW
Sbjct: 121  LAEPPYSLSVEKVFLIGGGQILREALNAAECDAIHITEIKTSVECDTFIPPIDMSIYQPW 180

Query: 1276 YSSSLIEENGVPYCFVTYVRLNTN-GGHLDSGHGISCNGSTSRPKGLKLSDFTFLPKFIF 1100
            YSS+ +EENG+ YCF TYVRL T+  G ++SGH +SCNGSTSR K  KLSDFT+LPKFIF
Sbjct: 181  YSSTPVEENGIQYCFATYVRLRTSTSGPVNSGHELSCNGSTSRSKRPKLSDFTYLPKFIF 240

Query: 1099 EKHEEFLYLRLVQDIISNGNNKDDRTGTGTLSKFGCQMRFNLRKSFPLLTTKRVFWRGVV 920
            EKHEEF YLRLVQDIISNGN+KDDRTGTGTLS FGCQM FNLRKSFPLLTTKRVFWRGVV
Sbjct: 241  EKHEEFQYLRLVQDIISNGNSKDDRTGTGTLSNFGCQMHFNLRKSFPLLTTKRVFWRGVV 300

Query: 919  EELLWFISGSTNAKILQEKGIHIWDGNASREFLDSIGLTDREEGDLGPVYGFQWRHFGAR 740
            EELLWFISGSTNAKILQEKGIHIWDGNASREFLDSIGLTDREEGDLGP+YGFQWRHFGAR
Sbjct: 301  EELLWFISGSTNAKILQEKGIHIWDGNASREFLDSIGLTDREEGDLGPIYGFQWRHFGAR 360

Query: 739  YTNMHADYTGQGFDQLLDVIDKIKNKPDDRRIILSAWNPSDLKLMALPPCHMFAQFYVAN 560
            YTNMHADYTGQGFDQLLDVIDKIKNKPDDRRIILSAWNPSDLKLMALPPCHMFAQFYVAN
Sbjct: 361  YTNMHADYTGQGFDQLLDVIDKIKNKPDDRRIILSAWNPSDLKLMALPPCHMFAQFYVAN 420

Query: 559  GELSCQMYQRSADMGLGVPFNIASYSLLTCMIAHVCGLVPGDFVHVIGDAHVYKTHVSPL 380
            GELSCQMYQRSADMGLGVPFNIASY+LLTCMIAHVCGL+PG+FVHVIGDAHVYKTH+SPL
Sbjct: 421  GELSCQMYQRSADMGLGVPFNIASYALLTCMIAHVCGLIPGEFVHVIGDAHVYKTHISPL 480

Query: 379  QEQLKKLPRPFPILKINPHKKDIDSFVAADFELKNYEPHPKLEMKMAV 236
            QEQLKKLPRPFPILKINP KKDIDSFVAADFEL+NYEPH KLEMKMAV
Sbjct: 481  QEQLKKLPRPFPILKINPEKKDIDSFVAADFELRNYEPHQKLEMKMAV 528


>ref|XP_012843023.1| PREDICTED: bifunctional dihydrofolate reductase-thymidylate synthase
            1-like isoform X1 [Erythranthe guttata]
          Length = 584

 Score =  982 bits (2539), Expect = 0.0
 Identities = 477/567 (84%), Positives = 509/567 (89%)
 Frame = -1

Query: 1936 VVLGSFLRGIFGLSSVSSFVCSFETLKPFVAQRFCRRYLVMGGDSIEFFSNGNTNTQPIP 1757
            V LGSF   IF  SS SSF+ SF++LKPF AQRFCRRYL M  DSI+  SNGN N Q IP
Sbjct: 27   VTLGSFRNSIFRASSQSSFILSFKSLKPFAAQRFCRRYLSMASDSIQCVSNGNDNAQSIP 86

Query: 1756 QRTYQVVVAATPDMGIGKDGKLPWRLPGDLKFFKEITASTSDPNKKNVVMMGRKTWESIP 1577
            +R+YQVVVAATPDMGIGK+GKLPWRLPGDLKFFKEITA+TSDPNKKN V+MGRKTWESIP
Sbjct: 87   ERSYQVVVAATPDMGIGKEGKLPWRLPGDLKFFKEITATTSDPNKKNAVLMGRKTWESIP 146

Query: 1576 PQFRPLPGRLNVILTRSGSSDVPAAENVIFCGSLPSALKLLEEPPYSFSIEKVFLIGGGQ 1397
            PQFRPLPGRLNV+LTRSGSSD  + E+V+FCGS+ SALKLL  PPYSF+IEKVFLIGGGQ
Sbjct: 147  PQFRPLPGRLNVVLTRSGSSDSNSDESVVFCGSMSSALKLLAGPPYSFNIEKVFLIGGGQ 206

Query: 1396 ILREALNAPECDAIHITEIKTYIDCDTFIPPIDMSLYQPWYSSSLIEENGVPYCFVTYVR 1217
            ILREA NA +CDAIHITE+K++I+CDTFIPPIDMS+YQPWYSSS+IEENG+ YCF TYVR
Sbjct: 207  ILREAFNALQCDAIHITELKSFIECDTFIPPIDMSVYQPWYSSSVIEENGIKYCFATYVR 266

Query: 1216 LNTNGGHLDSGHGISCNGSTSRPKGLKLSDFTFLPKFIFEKHEEFLYLRLVQDIISNGNN 1037
            L  +         I    STS    LKLSDFTFLPK IF+KHEEFLYLRLVQDIISNGNN
Sbjct: 267  LKNS---------IKGPVSTSHSNRLKLSDFTFLPKHIFDKHEEFLYLRLVQDIISNGNN 317

Query: 1036 KDDRTGTGTLSKFGCQMRFNLRKSFPLLTTKRVFWRGVVEELLWFISGSTNAKILQEKGI 857
            KDDRTGTGTLSKFGCQ+RFNLRKSFPLLTTKRVFWRGVVEELLWFISGSTNAKILQEKGI
Sbjct: 318  KDDRTGTGTLSKFGCQIRFNLRKSFPLLTTKRVFWRGVVEELLWFISGSTNAKILQEKGI 377

Query: 856  HIWDGNASREFLDSIGLTDREEGDLGPVYGFQWRHFGARYTNMHADYTGQGFDQLLDVID 677
            HIWDGNASR+FLDSIGLT+REEGDLGPVYGFQWRHFGARYTNMH DYTGQG DQL+DVID
Sbjct: 378  HIWDGNASRDFLDSIGLTEREEGDLGPVYGFQWRHFGARYTNMHDDYTGQGIDQLMDVID 437

Query: 676  KIKNKPDDRRIILSAWNPSDLKLMALPPCHMFAQFYVANGELSCQMYQRSADMGLGVPFN 497
            KIKNKPDDRRIILSAWNPSDLKLMALPPCHM AQFYVANGELSCQMYQRSADMGLGVPFN
Sbjct: 438  KIKNKPDDRRIILSAWNPSDLKLMALPPCHMSAQFYVANGELSCQMYQRSADMGLGVPFN 497

Query: 496  IASYSLLTCMIAHVCGLVPGDFVHVIGDAHVYKTHVSPLQEQLKKLPRPFPILKINPHKK 317
            IASY+LLTCMIAHVCGLVPGDF+HV GDAHVYKTHV PLQEQLKKLPRPFPIL+IN  KK
Sbjct: 498  IASYALLTCMIAHVCGLVPGDFIHVFGDAHVYKTHVGPLQEQLKKLPRPFPILRINTEKK 557

Query: 316  DIDSFVAADFELKNYEPHPKLEMKMAV 236
            DIDSFVA DFEL NYEPH KLEMKMAV
Sbjct: 558  DIDSFVAGDFELVNYEPHQKLEMKMAV 584


>ref|XP_020548650.1| putative bifunctional dihydrofolate reductase-thymidylate synthase
            isoform X2 [Sesamum indicum]
          Length = 569

 Score =  980 bits (2533), Expect = 0.0
 Identities = 482/568 (84%), Positives = 508/568 (89%), Gaps = 1/568 (0%)
 Frame = -1

Query: 1936 VVLGSFLRGIFGLSSVSSFVCSFETLKPFVAQRFCRRYLVMGGDSIEFFSNGNTNTQPIP 1757
            V LGSF   I      SS   + ETLK F  QRFCRRYLVMGGD+IE FSNGNT T+PI 
Sbjct: 18   VTLGSFGSNILSAWG-SSLPQAPETLKAFNTQRFCRRYLVMGGDAIECFSNGNTTTEPIS 76

Query: 1756 QRTYQVVVAATPDMGIGKDGKLPWRLPGDLKFFKEITASTSDPNKKNVVMMGRKTWESIP 1577
            QRTYQVVVAATPDMGIGKDGKLPWRLPGDLKFFKEITA+TSDPNKKN VMMGR+TWESIP
Sbjct: 77   QRTYQVVVAATPDMGIGKDGKLPWRLPGDLKFFKEITATTSDPNKKNAVMMGRRTWESIP 136

Query: 1576 PQFRPLPGRLNVILTRSGSSDVPAAENVIFCGSLPSALKLLEEPPYSFSIEKVFLIGGGQ 1397
            PQFRPLPGRLNV+LTRS SSDV AAENVI C S+ SALKLL EPPYS S+EKVFLIGGGQ
Sbjct: 137  PQFRPLPGRLNVVLTRSASSDVAAAENVISCRSMSSALKLLAEPPYSLSVEKVFLIGGGQ 196

Query: 1396 ILREALNAPECDAIHITEIKTYIDCDTFIPPIDMSLYQPWYSSSLIEENGVPYCFVTYVR 1217
            ILREALNA ECDAIHITEIKT ++CDTFIPPIDMS+YQPWYSS+ +EENG+ YCF TYVR
Sbjct: 197  ILREALNAAECDAIHITEIKTSVECDTFIPPIDMSIYQPWYSSTPVEENGIQYCFATYVR 256

Query: 1216 LNTN-GGHLDSGHGISCNGSTSRPKGLKLSDFTFLPKFIFEKHEEFLYLRLVQDIISNGN 1040
            L T+  G ++SGH +SCNGSTSR K  KLSDFT+LPKFIFEKHEEF YLRLVQDIISNGN
Sbjct: 257  LRTSTSGPVNSGHELSCNGSTSRSKRPKLSDFTYLPKFIFEKHEEFQYLRLVQDIISNGN 316

Query: 1039 NKDDRTGTGTLSKFGCQMRFNLRKSFPLLTTKRVFWRGVVEELLWFISGSTNAKILQEKG 860
            +KDDRTGTGTLS FGCQ               RVFWRGVVEELLWFISGSTNAKILQEKG
Sbjct: 317  SKDDRTGTGTLSNFGCQ---------------RVFWRGVVEELLWFISGSTNAKILQEKG 361

Query: 859  IHIWDGNASREFLDSIGLTDREEGDLGPVYGFQWRHFGARYTNMHADYTGQGFDQLLDVI 680
            IHIWDGNASREFLDSIGLTDREEGDLGP+YGFQWRHFGARYTNMHADYTGQGFDQLLDVI
Sbjct: 362  IHIWDGNASREFLDSIGLTDREEGDLGPIYGFQWRHFGARYTNMHADYTGQGFDQLLDVI 421

Query: 679  DKIKNKPDDRRIILSAWNPSDLKLMALPPCHMFAQFYVANGELSCQMYQRSADMGLGVPF 500
            DKIKNKPDDRRIILSAWNPSDLKLMALPPCHMFAQFYVANGELSCQMYQRSADMGLGVPF
Sbjct: 422  DKIKNKPDDRRIILSAWNPSDLKLMALPPCHMFAQFYVANGELSCQMYQRSADMGLGVPF 481

Query: 499  NIASYSLLTCMIAHVCGLVPGDFVHVIGDAHVYKTHVSPLQEQLKKLPRPFPILKINPHK 320
            NIASY+LLTCMIAHVCGL+PG+FVHVIGDAHVYKTH+SPLQEQLKKLPRPFPILKINP K
Sbjct: 482  NIASYALLTCMIAHVCGLIPGEFVHVIGDAHVYKTHISPLQEQLKKLPRPFPILKINPEK 541

Query: 319  KDIDSFVAADFELKNYEPHPKLEMKMAV 236
            KDIDSFVAADFEL+NYEPH KLEMKMAV
Sbjct: 542  KDIDSFVAADFELRNYEPHQKLEMKMAV 569


>ref|XP_012843024.1| PREDICTED: bifunctional dihydrofolate reductase-thymidylate synthase
            1-like isoform X2 [Erythranthe guttata]
 ref|XP_012843025.1| PREDICTED: bifunctional dihydrofolate reductase-thymidylate synthase
            1-like isoform X2 [Erythranthe guttata]
 gb|EYU32770.1| hypothetical protein MIMGU_mgv1a004601mg [Erythranthe guttata]
          Length = 518

 Score =  931 bits (2406), Expect = 0.0
 Identities = 450/527 (85%), Positives = 479/527 (90%)
 Frame = -1

Query: 1816 MGGDSIEFFSNGNTNTQPIPQRTYQVVVAATPDMGIGKDGKLPWRLPGDLKFFKEITAST 1637
            M  DSI+  SNGN N Q IP+R+YQVVVAATPDMGIGK+GKLPWRLPGDLKFFKEITA+T
Sbjct: 1    MASDSIQCVSNGNDNAQSIPERSYQVVVAATPDMGIGKEGKLPWRLPGDLKFFKEITATT 60

Query: 1636 SDPNKKNVVMMGRKTWESIPPQFRPLPGRLNVILTRSGSSDVPAAENVIFCGSLPSALKL 1457
            SDPNKKN V+MGRKTWESIPPQFRPLPGRLNV+LTRSGSSD  + E+V+FCGS+ SALKL
Sbjct: 61   SDPNKKNAVLMGRKTWESIPPQFRPLPGRLNVVLTRSGSSDSNSDESVVFCGSMSSALKL 120

Query: 1456 LEEPPYSFSIEKVFLIGGGQILREALNAPECDAIHITEIKTYIDCDTFIPPIDMSLYQPW 1277
            L  PPYSF+IEKVFLIGGGQILREA NA +CDAIHITE+K++I+CDTFIPPIDMS+YQPW
Sbjct: 121  LAGPPYSFNIEKVFLIGGGQILREAFNALQCDAIHITELKSFIECDTFIPPIDMSVYQPW 180

Query: 1276 YSSSLIEENGVPYCFVTYVRLNTNGGHLDSGHGISCNGSTSRPKGLKLSDFTFLPKFIFE 1097
            YSSS+IEENG+ YCF TYVRL  +         I    STS    LKLSDFTFLPK IF+
Sbjct: 181  YSSSVIEENGIKYCFATYVRLKNS---------IKGPVSTSHSNRLKLSDFTFLPKHIFD 231

Query: 1096 KHEEFLYLRLVQDIISNGNNKDDRTGTGTLSKFGCQMRFNLRKSFPLLTTKRVFWRGVVE 917
            KHEEFLYLRLVQDIISNGNNKDDRTGTGTLSKFGCQ+RFNLRKSFPLLTTKRVFWRGVVE
Sbjct: 232  KHEEFLYLRLVQDIISNGNNKDDRTGTGTLSKFGCQIRFNLRKSFPLLTTKRVFWRGVVE 291

Query: 916  ELLWFISGSTNAKILQEKGIHIWDGNASREFLDSIGLTDREEGDLGPVYGFQWRHFGARY 737
            ELLWFISGSTNAKILQEKGIHIWDGNASR+FLDSIGLT+REEGDLGPVYGFQWRHFGARY
Sbjct: 292  ELLWFISGSTNAKILQEKGIHIWDGNASRDFLDSIGLTEREEGDLGPVYGFQWRHFGARY 351

Query: 736  TNMHADYTGQGFDQLLDVIDKIKNKPDDRRIILSAWNPSDLKLMALPPCHMFAQFYVANG 557
            TNMH DYTGQG DQL+DVIDKIKNKPDDRRIILSAWNPSDLKLMALPPCHM AQFYVANG
Sbjct: 352  TNMHDDYTGQGIDQLMDVIDKIKNKPDDRRIILSAWNPSDLKLMALPPCHMSAQFYVANG 411

Query: 556  ELSCQMYQRSADMGLGVPFNIASYSLLTCMIAHVCGLVPGDFVHVIGDAHVYKTHVSPLQ 377
            ELSCQMYQRSADMGLGVPFNIASY+LLTCMIAHVCGLVPGDF+HV GDAHVYKTHV PLQ
Sbjct: 412  ELSCQMYQRSADMGLGVPFNIASYALLTCMIAHVCGLVPGDFIHVFGDAHVYKTHVGPLQ 471

Query: 376  EQLKKLPRPFPILKINPHKKDIDSFVAADFELKNYEPHPKLEMKMAV 236
            EQLKKLPRPFPIL+IN  KKDIDSFVA DFEL NYEPH KLEMKMAV
Sbjct: 472  EQLKKLPRPFPILRINTEKKDIDSFVAGDFELVNYEPHQKLEMKMAV 518


>ref|XP_022884764.1| putative bifunctional dihydrofolate reductase-thymidylate synthase
            isoform X3 [Olea europaea var. sylvestris]
          Length = 597

 Score =  894 bits (2310), Expect = 0.0
 Identities = 438/566 (77%), Positives = 483/566 (85%), Gaps = 1/566 (0%)
 Frame = -1

Query: 1930 LGSFLRGIFGLSSVSSFVCSFETLKPFVAQRFCRRYLVMGGDSIEFFSNGNTNTQPIPQR 1751
            L S     F  +SV+SF  SF     F  QR    Y VM  +SI   S+GNTNTQ    R
Sbjct: 32   LSSCHSNFFSSASVTSFTRSFRVPNVFTKQRSYCEYSVMSENSIACHSDGNTNTQQPLHR 91

Query: 1750 TYQVVVAATPDMGIGKDGKLPWRLPGDLKFFKEITASTSDPNKKNVVMMGRKTWESIPPQ 1571
            TYQVVVAAT DMGIGKDGKLPW+LP DLKFFKE+T +TSD  KKN V+MGRKTWESIPPQ
Sbjct: 92   TYQVVVAATCDMGIGKDGKLPWKLPSDLKFFKELTMTTSDQEKKNAVIMGRKTWESIPPQ 151

Query: 1570 FRPLPGRLNVILTRSGSSDVPAAENVIFCGSLPSALKLLEEPPYSFSIEKVFLIGGGQIL 1391
            FRPLPGRLNVILTRSGS D+  AENVI CGS+PSALKLL E PY+  IEKVF+IGGGQIL
Sbjct: 152  FRPLPGRLNVILTRSGSFDIATAENVIICGSIPSALKLLAESPYNILIEKVFMIGGGQIL 211

Query: 1390 REALNAPECDAIHITEIKTYIDCDTFIPPIDMSLYQPWYSSSLIEENGVPYCFVTYVRLN 1211
             EALNAPECDAIH+TEI+++++CDTFIP +D+S+YQPWY SS + EN + Y FVT+VRL 
Sbjct: 212  GEALNAPECDAIHMTEIESHVECDTFIPAVDLSVYQPWYMSSPVVENSIRYFFVTFVRLK 271

Query: 1210 TNG-GHLDSGHGISCNGSTSRPKGLKLSDFTFLPKFIFEKHEEFLYLRLVQDIISNGNNK 1034
            T+  G  +S   +S  GS    K  K S+FTFLPK IFEKHEEFLYL+LVQDIISNGN+K
Sbjct: 272  TSTMGPTNSSLEVSYTGSVLDYKKFKYSNFTFLPKTIFEKHEEFLYLKLVQDIISNGNDK 331

Query: 1033 DDRTGTGTLSKFGCQMRFNLRKSFPLLTTKRVFWRGVVEELLWFISGSTNAKILQEKGIH 854
             D+ GTGTLSKFGCQMRFNLRKSFPLLTTK +FWRGVVEELLWF+SGSTNAK+LQEK I+
Sbjct: 332  GDQMGTGTLSKFGCQMRFNLRKSFPLLTTKSIFWRGVVEELLWFLSGSTNAKVLQEKAIN 391

Query: 853  IWDGNASREFLDSIGLTDREEGDLGPVYGFQWRHFGARYTNMHADYTGQGFDQLLDVIDK 674
            IWDGNAS E+LDSIGLTDREEGDLGPVYGFQWRHFGARYTNMH DYTGQGFDQLLDVIDK
Sbjct: 392  IWDGNASSEYLDSIGLTDREEGDLGPVYGFQWRHFGARYTNMHTDYTGQGFDQLLDVIDK 451

Query: 673  IKNKPDDRRIILSAWNPSDLKLMALPPCHMFAQFYVANGELSCQMYQRSADMGLGVPFNI 494
            IKN+P+DRRIILSAWNPSDLKLMALPPCHMFAQFYVANGELSCQMYQ SA+MGLGVPFNI
Sbjct: 452  IKNEPNDRRIILSAWNPSDLKLMALPPCHMFAQFYVANGELSCQMYQHSANMGLGVPFNI 511

Query: 493  ASYSLLTCMIAHVCGLVPGDFVHVIGDAHVYKTHVSPLQEQLKKLPRPFPILKINPHKKD 314
            ASYSLLTCMIAHVCGLVPGD +HVIGDAHVYKTH+SPLQEQLK++P+PFPILKINP  KD
Sbjct: 512  ASYSLLTCMIAHVCGLVPGDLIHVIGDAHVYKTHISPLQEQLKQIPKPFPILKINPQTKD 571

Query: 313  IDSFVAADFELKNYEPHPKLEMKMAV 236
            IDSFVAADFEL NYEPH KLEMK+AV
Sbjct: 572  IDSFVAADFELINYEPHSKLEMKLAV 597


>ref|XP_010254750.1| PREDICTED: putative bifunctional dihydrofolate reductase-thymidylate
            synthase isoform X2 [Nelumbo nucifera]
          Length = 569

 Score =  872 bits (2253), Expect = 0.0
 Identities = 419/558 (75%), Positives = 477/558 (85%), Gaps = 7/558 (1%)
 Frame = -1

Query: 1888 SSFVCSFETLKPFVA------QRFCRRYLVMGGDSIEFFSNGNTNTQPIPQRTYQVVVAA 1727
            SSFV    + + F A       R C ++ VM G++I    NGN + QP P+RT+QVVVAA
Sbjct: 13   SSFVSDLSSSQLFGALYSIANYRSCLKFSVMAGETIMNVPNGNASIQPDPKRTFQVVVAA 72

Query: 1726 TPDMGIGKDGKLPWRLPGDLKFFKEITASTSDPNKKNVVMMGRKTWESIPPQFRPLPGRL 1547
            T  MGIGKDGKLPWRLP DLKFF+E+T  TSDP KKN V+MGRKTWE IPP+ RPLPGRL
Sbjct: 73   TKSMGIGKDGKLPWRLPSDLKFFREVTMGTSDPAKKNAVIMGRKTWEGIPPEHRPLPGRL 132

Query: 1546 NVILTRSGSSDVPAAENVIFCGSLPSALKLLEEPPYSFSIEKVFLIGGGQILREALNAPE 1367
            NV+LTRSGS D+  AENV+ CGS+ SAL+LL   PY  SIEKVF+IGGGQILRE+LNAPE
Sbjct: 133  NVVLTRSGSFDIATAENVVICGSMSSALELLASSPYCLSIEKVFVIGGGQILRESLNAPE 192

Query: 1366 CDAIHITEIKTYIDCDTFIPPIDMSLYQPWYSSSLIEENGVPYCFVTYVRLNTNGG-HLD 1190
            CDAIHITEI+T  +CDTFIPPI++S++QPWYSS  + EN +   FVTYVR+  +   +L 
Sbjct: 193  CDAIHITEIETSFECDTFIPPIELSVFQPWYSSFPLIENNIRCSFVTYVRVRRSAAEYLY 252

Query: 1189 SGHGISCNGSTSRPKGLKLSDFTFLPKFIFEKHEEFLYLRLVQDIISNGNNKDDRTGTGT 1010
              +G   +G+++  K  ++  F+FLPK IFE+HEE++YLRLV+DIISNGN KDDRTGTGT
Sbjct: 253  QDNGGMFDGNSNNTK-FEIEKFSFLPKMIFERHEEYMYLRLVEDIISNGNQKDDRTGTGT 311

Query: 1009 LSKFGCQMRFNLRKSFPLLTTKRVFWRGVVEELLWFISGSTNAKILQEKGIHIWDGNASR 830
            LSKFGCQM FNLRKSFPLLTTK+VFWRGVVEELLWFISGSTNAK+LQEKGIHIWDGNASR
Sbjct: 312  LSKFGCQMHFNLRKSFPLLTTKKVFWRGVVEELLWFISGSTNAKVLQEKGIHIWDGNASR 371

Query: 829  EFLDSIGLTDREEGDLGPVYGFQWRHFGARYTNMHADYTGQGFDQLLDVIDKIKNKPDDR 650
            ++LDSIGLTDREEGDLGP+YGFQWRH GARYTNMHADY+GQGFDQLLDVIDKIKNKPDDR
Sbjct: 372  DYLDSIGLTDREEGDLGPIYGFQWRHHGARYTNMHADYSGQGFDQLLDVIDKIKNKPDDR 431

Query: 649  RIILSAWNPSDLKLMALPPCHMFAQFYVANGELSCQMYQRSADMGLGVPFNIASYSLLTC 470
            RIILSAWNPSDLKLMALPPCHMFAQFYV NGELSCQMYQRSADMGLGVPFNIASY+LLTC
Sbjct: 432  RIILSAWNPSDLKLMALPPCHMFAQFYVVNGELSCQMYQRSADMGLGVPFNIASYALLTC 491

Query: 469  MIAHVCGLVPGDFVHVIGDAHVYKTHVSPLQEQLKKLPRPFPILKINPHKKDIDSFVAAD 290
            MIAHVC L+PGDF+HVIGDAHVY+THV PLQEQL+KLP+PFPILKINPHKKDIDSFVA D
Sbjct: 492  MIAHVCDLIPGDFIHVIGDAHVYRTHVRPLQEQLQKLPKPFPILKINPHKKDIDSFVATD 551

Query: 289  FELKNYEPHPKLEMKMAV 236
            F+L  Y+PH K+EMKMAV
Sbjct: 552  FKLVGYDPHQKIEMKMAV 569


>ref|XP_010254749.1| PREDICTED: putative bifunctional dihydrofolate reductase-thymidylate
            synthase isoform X1 [Nelumbo nucifera]
          Length = 578

 Score =  872 bits (2253), Expect = 0.0
 Identities = 419/558 (75%), Positives = 477/558 (85%), Gaps = 7/558 (1%)
 Frame = -1

Query: 1888 SSFVCSFETLKPFVA------QRFCRRYLVMGGDSIEFFSNGNTNTQPIPQRTYQVVVAA 1727
            SSFV    + + F A       R C ++ VM G++I    NGN + QP P+RT+QVVVAA
Sbjct: 22   SSFVSDLSSSQLFGALYSIANYRSCLKFSVMAGETIMNVPNGNASIQPDPKRTFQVVVAA 81

Query: 1726 TPDMGIGKDGKLPWRLPGDLKFFKEITASTSDPNKKNVVMMGRKTWESIPPQFRPLPGRL 1547
            T  MGIGKDGKLPWRLP DLKFF+E+T  TSDP KKN V+MGRKTWE IPP+ RPLPGRL
Sbjct: 82   TKSMGIGKDGKLPWRLPSDLKFFREVTMGTSDPAKKNAVIMGRKTWEGIPPEHRPLPGRL 141

Query: 1546 NVILTRSGSSDVPAAENVIFCGSLPSALKLLEEPPYSFSIEKVFLIGGGQILREALNAPE 1367
            NV+LTRSGS D+  AENV+ CGS+ SAL+LL   PY  SIEKVF+IGGGQILRE+LNAPE
Sbjct: 142  NVVLTRSGSFDIATAENVVICGSMSSALELLASSPYCLSIEKVFVIGGGQILRESLNAPE 201

Query: 1366 CDAIHITEIKTYIDCDTFIPPIDMSLYQPWYSSSLIEENGVPYCFVTYVRLNTNGG-HLD 1190
            CDAIHITEI+T  +CDTFIPPI++S++QPWYSS  + EN +   FVTYVR+  +   +L 
Sbjct: 202  CDAIHITEIETSFECDTFIPPIELSVFQPWYSSFPLIENNIRCSFVTYVRVRRSAAEYLY 261

Query: 1189 SGHGISCNGSTSRPKGLKLSDFTFLPKFIFEKHEEFLYLRLVQDIISNGNNKDDRTGTGT 1010
              +G   +G+++  K  ++  F+FLPK IFE+HEE++YLRLV+DIISNGN KDDRTGTGT
Sbjct: 262  QDNGGMFDGNSNNTK-FEIEKFSFLPKMIFERHEEYMYLRLVEDIISNGNQKDDRTGTGT 320

Query: 1009 LSKFGCQMRFNLRKSFPLLTTKRVFWRGVVEELLWFISGSTNAKILQEKGIHIWDGNASR 830
            LSKFGCQM FNLRKSFPLLTTK+VFWRGVVEELLWFISGSTNAK+LQEKGIHIWDGNASR
Sbjct: 321  LSKFGCQMHFNLRKSFPLLTTKKVFWRGVVEELLWFISGSTNAKVLQEKGIHIWDGNASR 380

Query: 829  EFLDSIGLTDREEGDLGPVYGFQWRHFGARYTNMHADYTGQGFDQLLDVIDKIKNKPDDR 650
            ++LDSIGLTDREEGDLGP+YGFQWRH GARYTNMHADY+GQGFDQLLDVIDKIKNKPDDR
Sbjct: 381  DYLDSIGLTDREEGDLGPIYGFQWRHHGARYTNMHADYSGQGFDQLLDVIDKIKNKPDDR 440

Query: 649  RIILSAWNPSDLKLMALPPCHMFAQFYVANGELSCQMYQRSADMGLGVPFNIASYSLLTC 470
            RIILSAWNPSDLKLMALPPCHMFAQFYV NGELSCQMYQRSADMGLGVPFNIASY+LLTC
Sbjct: 441  RIILSAWNPSDLKLMALPPCHMFAQFYVVNGELSCQMYQRSADMGLGVPFNIASYALLTC 500

Query: 469  MIAHVCGLVPGDFVHVIGDAHVYKTHVSPLQEQLKKLPRPFPILKINPHKKDIDSFVAAD 290
            MIAHVC L+PGDF+HVIGDAHVY+THV PLQEQL+KLP+PFPILKINPHKKDIDSFVA D
Sbjct: 501  MIAHVCDLIPGDFIHVIGDAHVYRTHVRPLQEQLQKLPKPFPILKINPHKKDIDSFVATD 560

Query: 289  FELKNYEPHPKLEMKMAV 236
            F+L  Y+PH K+EMKMAV
Sbjct: 561  FKLVGYDPHQKIEMKMAV 578


>ref|XP_010254751.1| PREDICTED: putative bifunctional dihydrofolate reductase-thymidylate
            synthase isoform X3 [Nelumbo nucifera]
 ref|XP_010254752.1| PREDICTED: putative bifunctional dihydrofolate reductase-thymidylate
            synthase isoform X3 [Nelumbo nucifera]
          Length = 527

 Score =  864 bits (2233), Expect = 0.0
 Identities = 410/528 (77%), Positives = 464/528 (87%), Gaps = 1/528 (0%)
 Frame = -1

Query: 1816 MGGDSIEFFSNGNTNTQPIPQRTYQVVVAATPDMGIGKDGKLPWRLPGDLKFFKEITAST 1637
            M G++I    NGN + QP P+RT+QVVVAAT  MGIGKDGKLPWRLP DLKFF+E+T  T
Sbjct: 1    MAGETIMNVPNGNASIQPDPKRTFQVVVAATKSMGIGKDGKLPWRLPSDLKFFREVTMGT 60

Query: 1636 SDPNKKNVVMMGRKTWESIPPQFRPLPGRLNVILTRSGSSDVPAAENVIFCGSLPSALKL 1457
            SDP KKN V+MGRKTWE IPP+ RPLPGRLNV+LTRSGS D+  AENV+ CGS+ SAL+L
Sbjct: 61   SDPAKKNAVIMGRKTWEGIPPEHRPLPGRLNVVLTRSGSFDIATAENVVICGSMSSALEL 120

Query: 1456 LEEPPYSFSIEKVFLIGGGQILREALNAPECDAIHITEIKTYIDCDTFIPPIDMSLYQPW 1277
            L   PY  SIEKVF+IGGGQILRE+LNAPECDAIHITEI+T  +CDTFIPPI++S++QPW
Sbjct: 121  LASSPYCLSIEKVFVIGGGQILRESLNAPECDAIHITEIETSFECDTFIPPIELSVFQPW 180

Query: 1276 YSSSLIEENGVPYCFVTYVRLNTNGG-HLDSGHGISCNGSTSRPKGLKLSDFTFLPKFIF 1100
            YSS  + EN +   FVTYVR+  +   +L   +G   +G+++  K  ++  F+FLPK IF
Sbjct: 181  YSSFPLIENNIRCSFVTYVRVRRSAAEYLYQDNGGMFDGNSNNTK-FEIEKFSFLPKMIF 239

Query: 1099 EKHEEFLYLRLVQDIISNGNNKDDRTGTGTLSKFGCQMRFNLRKSFPLLTTKRVFWRGVV 920
            E+HEE++YLRLV+DIISNGN KDDRTGTGTLSKFGCQM FNLRKSFPLLTTK+VFWRGVV
Sbjct: 240  ERHEEYMYLRLVEDIISNGNQKDDRTGTGTLSKFGCQMHFNLRKSFPLLTTKKVFWRGVV 299

Query: 919  EELLWFISGSTNAKILQEKGIHIWDGNASREFLDSIGLTDREEGDLGPVYGFQWRHFGAR 740
            EELLWFISGSTNAK+LQEKGIHIWDGNASR++LDSIGLTDREEGDLGP+YGFQWRH GAR
Sbjct: 300  EELLWFISGSTNAKVLQEKGIHIWDGNASRDYLDSIGLTDREEGDLGPIYGFQWRHHGAR 359

Query: 739  YTNMHADYTGQGFDQLLDVIDKIKNKPDDRRIILSAWNPSDLKLMALPPCHMFAQFYVAN 560
            YTNMHADY+GQGFDQLLDVIDKIKNKPDDRRIILSAWNPSDLKLMALPPCHMFAQFYV N
Sbjct: 360  YTNMHADYSGQGFDQLLDVIDKIKNKPDDRRIILSAWNPSDLKLMALPPCHMFAQFYVVN 419

Query: 559  GELSCQMYQRSADMGLGVPFNIASYSLLTCMIAHVCGLVPGDFVHVIGDAHVYKTHVSPL 380
            GELSCQMYQRSADMGLGVPFNIASY+LLTCMIAHVC L+PGDF+HVIGDAHVY+THV PL
Sbjct: 420  GELSCQMYQRSADMGLGVPFNIASYALLTCMIAHVCDLIPGDFIHVIGDAHVYRTHVRPL 479

Query: 379  QEQLKKLPRPFPILKINPHKKDIDSFVAADFELKNYEPHPKLEMKMAV 236
            QEQL+KLP+PFPILKINPHKKDIDSFVA DF+L  Y+PH K+EMKMAV
Sbjct: 480  QEQLQKLPKPFPILKINPHKKDIDSFVATDFKLVGYDPHQKIEMKMAV 527


>ref|XP_021653888.1| bifunctional dihydrofolate reductase-thymidylate synthase-like [Hevea
            brasiliensis]
          Length = 527

 Score =  858 bits (2217), Expect = 0.0
 Identities = 415/529 (78%), Positives = 460/529 (86%), Gaps = 2/529 (0%)
 Frame = -1

Query: 1816 MGGDSIEFFSNGNTNTQPIPQRTYQVVVAATPDMGIGKDGKLPWRLPGDLKFFKEITAST 1637
            M G+S    SNGN N QP PQRTYQVVVAAT DMGIGKDGKLPWRLP DLKFFK++T +T
Sbjct: 1    MAGESKANLSNGNANIQPAPQRTYQVVVAATRDMGIGKDGKLPWRLPSDLKFFKDVTLTT 60

Query: 1636 SDPNKKNVVMMGRKTWESIPPQFRPLPGRLNVILTRSGSSDVPAAENVIFCGSLPSALKL 1457
            SD  KKN V+MGRKTWESIP + RPLPGRLNV+LTRSGS D+  AENV+ CGSL SAL+L
Sbjct: 61   SDSGKKNAVIMGRKTWESIPLEHRPLPGRLNVVLTRSGSFDIATAENVVMCGSLSSALEL 120

Query: 1456 LEEPPYSFSIEKVFLIGGGQILREALNAPECDAIHITEIKTYIDCDTFIPPIDMSLYQPW 1277
            L   PY  SIEKVF+IGGGQILREALNAP CDAIHITEI+T IDCDTFIP ID +++QPW
Sbjct: 121  LAASPYCLSIEKVFVIGGGQILREALNAPGCDAIHITEIETNIDCDTFIPTIDSTVFQPW 180

Query: 1276 YSSSLIEENGVPYCFVTYVRLNTNG--GHLDSGHGISCNGSTSRPKGLKLSDFTFLPKFI 1103
            YSS  + EN + Y F TYVR+ ++    H    +G+S +  +   K L++  F+FLPK +
Sbjct: 181  YSSFPMVENSIRYSFATYVRVRSSAIESH-GQNNGLSPDSGSENSK-LEVKKFSFLPKMV 238

Query: 1102 FEKHEEFLYLRLVQDIISNGNNKDDRTGTGTLSKFGCQMRFNLRKSFPLLTTKRVFWRGV 923
            FE+HEE LYLRLVQDIIS+GN KDDRTGTGTLSKFGCQMRFNLRK+FPLLTTK+VFWRGV
Sbjct: 239  FERHEELLYLRLVQDIISDGNLKDDRTGTGTLSKFGCQMRFNLRKTFPLLTTKKVFWRGV 298

Query: 922  VEELLWFISGSTNAKILQEKGIHIWDGNASREFLDSIGLTDREEGDLGPVYGFQWRHFGA 743
            VEELLWFISGSTNAK+LQ+KGIHIWDGNASR++LD+IGL DREEGDLGPVYGFQWRHFGA
Sbjct: 299  VEELLWFISGSTNAKVLQDKGIHIWDGNASRDYLDNIGLKDREEGDLGPVYGFQWRHFGA 358

Query: 742  RYTNMHADYTGQGFDQLLDVIDKIKNKPDDRRIILSAWNPSDLKLMALPPCHMFAQFYVA 563
            RYTNMHADYTGQGFDQLLDVIDKIKN PDDRRIILSAWNPSDLKLMALPPCHMFAQFYVA
Sbjct: 359  RYTNMHADYTGQGFDQLLDVIDKIKNNPDDRRIILSAWNPSDLKLMALPPCHMFAQFYVA 418

Query: 562  NGELSCQMYQRSADMGLGVPFNIASYSLLTCMIAHVCGLVPGDFVHVIGDAHVYKTHVSP 383
            NGELSCQMYQRSADMGLGVPFNIASY+LLTCMIAHVC L PGDFVHV GDAHVY THV P
Sbjct: 419  NGELSCQMYQRSADMGLGVPFNIASYALLTCMIAHVCNLAPGDFVHVFGDAHVYSTHVRP 478

Query: 382  LQEQLKKLPRPFPILKINPHKKDIDSFVAADFELKNYEPHPKLEMKMAV 236
            LQEQL+KLP+PFPILKINP KK+IDSF+AADF+L  Y+PH K+EMKMAV
Sbjct: 479  LQEQLQKLPKPFPILKINPEKKNIDSFMAADFKLIGYDPHHKIEMKMAV 527


>ref|XP_021662680.1| bifunctional dihydrofolate reductase-thymidylate synthase 1-like
            [Hevea brasiliensis]
          Length = 550

 Score =  858 bits (2218), Expect = 0.0
 Identities = 416/539 (77%), Positives = 464/539 (86%), Gaps = 2/539 (0%)
 Frame = -1

Query: 1846 AQRFCRRYL-VMGGDSIEFFSNGNTNTQPIPQRTYQVVVAATPDMGIGKDGKLPWRLPGD 1670
            ++ FC  +  +M GDS    SNGN N QP PQRTYQVVVAAT DMGIGKDGKLPWRLP D
Sbjct: 13   SRNFCWAFFSIMAGDSKANLSNGNANIQPAPQRTYQVVVAATGDMGIGKDGKLPWRLPSD 72

Query: 1669 LKFFKEITASTSDPNKKNVVMMGRKTWESIPPQFRPLPGRLNVILTRSGSSDVPAAENVI 1490
            LKFFK++T +TSD  KKN V+MGRKTWESIP + RPLPGRLNV+LTRSGS D+  AENV+
Sbjct: 73   LKFFKDVTMTTSDSGKKNAVIMGRKTWESIPLEHRPLPGRLNVVLTRSGSFDIATAENVV 132

Query: 1489 FCGSLPSALKLLEEPPYSFSIEKVFLIGGGQILREALNAPECDAIHITEIKTYIDCDTFI 1310
             CGSL SAL+LL   PY  SIEK ++IGGGQILREALNAP CDAIHITEI+T IDCDTFI
Sbjct: 133  MCGSLSSALELLAASPYCLSIEKAYVIGGGQILREALNAPGCDAIHITEIETNIDCDTFI 192

Query: 1309 PPIDMSLYQPWYSSSLIEENGVPYCFVTYVRLNTNGGHLDS-GHGISCNGSTSRPKGLKL 1133
            P ID S++QPWYSS  + EN + YCF TYVR+ +     +   +G+S +  +   K  ++
Sbjct: 193  PTIDSSVFQPWYSSFPMVENNIRYCFATYVRVRSTAVESNGQNNGLSSDVGSENSK-FEV 251

Query: 1132 SDFTFLPKFIFEKHEEFLYLRLVQDIISNGNNKDDRTGTGTLSKFGCQMRFNLRKSFPLL 953
              F+FLPK +FE+HEEF YLRLVQDIIS+G  KDDRTGTGTLSKFGCQMRFNLRK+FPLL
Sbjct: 252  KKFSFLPKMVFERHEEFFYLRLVQDIISDGILKDDRTGTGTLSKFGCQMRFNLRKTFPLL 311

Query: 952  TTKRVFWRGVVEELLWFISGSTNAKILQEKGIHIWDGNASREFLDSIGLTDREEGDLGPV 773
            TTK+VFWRGVVEELLWFISGSTNAK+LQEKGIHIWDGNASR++LDSIGL DREEGDLGPV
Sbjct: 312  TTKKVFWRGVVEELLWFISGSTNAKVLQEKGIHIWDGNASRDYLDSIGLKDREEGDLGPV 371

Query: 772  YGFQWRHFGARYTNMHADYTGQGFDQLLDVIDKIKNKPDDRRIILSAWNPSDLKLMALPP 593
            YGFQWRHFGARY++MHADYTGQGFDQLLDVIDKIKN PDDRRIILSAWNPSDLKLMALPP
Sbjct: 372  YGFQWRHFGARYSDMHADYTGQGFDQLLDVIDKIKNNPDDRRIILSAWNPSDLKLMALPP 431

Query: 592  CHMFAQFYVANGELSCQMYQRSADMGLGVPFNIASYSLLTCMIAHVCGLVPGDFVHVIGD 413
            CHMFAQFYVA+GELSCQMYQRSADMGLGVPFNIASY+LLTCMIAHVC LVPGDFVHV GD
Sbjct: 432  CHMFAQFYVAHGELSCQMYQRSADMGLGVPFNIASYALLTCMIAHVCNLVPGDFVHVFGD 491

Query: 412  AHVYKTHVSPLQEQLKKLPRPFPILKINPHKKDIDSFVAADFELKNYEPHPKLEMKMAV 236
            AHVY THV PLQEQL+KLP+PFPILKINP KK+IDSFVAADF+L  Y+PH K+EMKMAV
Sbjct: 492  AHVYCTHVRPLQEQLQKLPKPFPILKINPDKKNIDSFVAADFKLIGYDPHNKIEMKMAV 550


>gb|OVA18766.1| Thymidylate synthase [Macleaya cordata]
          Length = 581

 Score =  859 bits (2219), Expect = 0.0
 Identities = 418/560 (74%), Positives = 473/560 (84%), Gaps = 2/560 (0%)
 Frame = -1

Query: 1909 IFGLSSVSSFVCSFETLKPFVAQRFCRRYLVMGGDSIEFFSNGNTNTQPIPQRTYQVVVA 1730
            + G+   SS    F  L      R C R+ VM G+S+   SNG+      P RTYQVVVA
Sbjct: 22   LLGVGFKSSSSQRFGALNAVAEYRSCLRFSVMAGNSVMNPSNGDAKIHTNPLRTYQVVVA 81

Query: 1729 ATPDMGIGKDGKLPWRLPGDLKFFKEITASTSDPNKKNVVMMGRKTWESIPPQFRPLPGR 1550
            AT +MGIGKDGKLPWRLP DLKFFKEITA TSDP+KKN V+MGRKTWESIP ++RPLPGR
Sbjct: 82   ATRNMGIGKDGKLPWRLPSDLKFFKEITAVTSDPSKKNAVIMGRKTWESIPLEYRPLPGR 141

Query: 1549 LNVILTRSGSSDVPAAENVIFCGSLPSALKLLEEPPYSFSIEKVFLIGGGQILREALNAP 1370
            LNV+LTRSGS D+  AENV+ CGS+ SAL+LL   PY  SIEKVF+IGGGQ+LREALNAP
Sbjct: 142  LNVVLTRSGSFDIATAENVLICGSMVSALELLAASPYCISIEKVFVIGGGQVLREALNAP 201

Query: 1369 ECDAIHITEIKTYIDCDTFIPPIDMSLYQPWYSSSLIEENGVPYCFVTYVRLNTNGGH-L 1193
            ECDAIH TEI+  I+CDTFIPPID +LY+PWYSS    EN + + F+TYVR+ T+    +
Sbjct: 202  ECDAIHFTEIEANIECDTFIPPIDSALYKPWYSSFPRVENNIRHSFMTYVRVRTSVEESV 261

Query: 1192 DSGHGISCNG-STSRPKGLKLSDFTFLPKFIFEKHEEFLYLRLVQDIISNGNNKDDRTGT 1016
               +G++ +  S+   K  ++  ++FLPK IFEKHEE++YLRLVQDIIS+G  KDDRTGT
Sbjct: 262  AFNNGVTVDSCSSDSNKSDEVKKYSFLPKMIFEKHEEYIYLRLVQDIISDGITKDDRTGT 321

Query: 1015 GTLSKFGCQMRFNLRKSFPLLTTKRVFWRGVVEELLWFISGSTNAKILQEKGIHIWDGNA 836
            GTLSKFGCQMRFNLRKSFPLLTTK+VFWRGVVEELLWFISGSTNAK+LQEKGIHIWDGNA
Sbjct: 322  GTLSKFGCQMRFNLRKSFPLLTTKKVFWRGVVEELLWFISGSTNAKVLQEKGIHIWDGNA 381

Query: 835  SREFLDSIGLTDREEGDLGPVYGFQWRHFGARYTNMHADYTGQGFDQLLDVIDKIKNKPD 656
            SR++LDSIGLTDREEGDLGP+YGFQWRHFGARYTNMHA+Y+GQGFDQLLDVIDKIKNKPD
Sbjct: 382  SRDYLDSIGLTDREEGDLGPIYGFQWRHFGARYTNMHANYSGQGFDQLLDVIDKIKNKPD 441

Query: 655  DRRIILSAWNPSDLKLMALPPCHMFAQFYVANGELSCQMYQRSADMGLGVPFNIASYSLL 476
            DRRI+LSAWNPSDL LMALPPCHMFAQFYVANGELSCQMYQRSADMGLGVPFNIASYSLL
Sbjct: 442  DRRIVLSAWNPSDLCLMALPPCHMFAQFYVANGELSCQMYQRSADMGLGVPFNIASYSLL 501

Query: 475  TCMIAHVCGLVPGDFVHVIGDAHVYKTHVSPLQEQLKKLPRPFPILKINPHKKDIDSFVA 296
            TCMIAHVC LVPGDFVHVIGDAHVY+THV PLQ+QL+KLPRPFP LKINP KKDIDSF  
Sbjct: 502  TCMIAHVCDLVPGDFVHVIGDAHVYRTHVRPLQKQLQKLPRPFPTLKINPEKKDIDSFAV 561

Query: 295  ADFELKNYEPHPKLEMKMAV 236
             DF+L +Y+PH K+EMKMAV
Sbjct: 562  TDFQLMDYDPHQKIEMKMAV 581


>ref|XP_021658747.1| bifunctional dihydrofolate reductase-thymidylate synthase-like [Hevea
            brasiliensis]
          Length = 550

 Score =  856 bits (2212), Expect = 0.0
 Identities = 414/539 (76%), Positives = 463/539 (85%), Gaps = 2/539 (0%)
 Frame = -1

Query: 1846 AQRFCRRYL-VMGGDSIEFFSNGNTNTQPIPQRTYQVVVAATPDMGIGKDGKLPWRLPGD 1670
            ++ FC  +  +M GDS    SNGN N QP PQRTYQVVVAAT DMGIGKDGKLPWRLP D
Sbjct: 13   SRNFCWAFFSIMAGDSKANLSNGNANIQPAPQRTYQVVVAATGDMGIGKDGKLPWRLPSD 72

Query: 1669 LKFFKEITASTSDPNKKNVVMMGRKTWESIPPQFRPLPGRLNVILTRSGSSDVPAAENVI 1490
            LKFFK++T +TSD  KKN V+MGRKTWESIP + RPLPGRLNV+LTRSGS D+  AENV+
Sbjct: 73   LKFFKDVTMTTSDSGKKNAVIMGRKTWESIPLEHRPLPGRLNVVLTRSGSFDIATAENVV 132

Query: 1489 FCGSLPSALKLLEEPPYSFSIEKVFLIGGGQILREALNAPECDAIHITEIKTYIDCDTFI 1310
             CGSL SAL+LL   PY  SIEK ++IGGGQILREALNAP CDAIHITEI+  IDCDTFI
Sbjct: 133  MCGSLSSALELLAASPYCLSIEKAYVIGGGQILREALNAPGCDAIHITEIEANIDCDTFI 192

Query: 1309 PPIDMSLYQPWYSSSLIEENGVPYCFVTYVRLNTNGGHLDS-GHGISCNGSTSRPKGLKL 1133
            P ID S++QPWYSS  + EN + YCF TYVR+ +     +   +G+S +  +   K  ++
Sbjct: 193  PTIDSSVFQPWYSSFPMVENNIRYCFATYVRVRSTAVESNGQNNGLSADVGSENSK-FEV 251

Query: 1132 SDFTFLPKFIFEKHEEFLYLRLVQDIISNGNNKDDRTGTGTLSKFGCQMRFNLRKSFPLL 953
              F+FLPK +FE+HEEF YLRLVQDIIS+G  KDDRTGTGTLSKFGCQMRFNLRK+FPLL
Sbjct: 252  KKFSFLPKMVFERHEEFFYLRLVQDIISDGILKDDRTGTGTLSKFGCQMRFNLRKTFPLL 311

Query: 952  TTKRVFWRGVVEELLWFISGSTNAKILQEKGIHIWDGNASREFLDSIGLTDREEGDLGPV 773
            TTK+VFWRGVVEELLWFISGSTNAK+LQEKGIHIWDGNASR++LDSIGL DREEGDLGPV
Sbjct: 312  TTKKVFWRGVVEELLWFISGSTNAKVLQEKGIHIWDGNASRDYLDSIGLKDREEGDLGPV 371

Query: 772  YGFQWRHFGARYTNMHADYTGQGFDQLLDVIDKIKNKPDDRRIILSAWNPSDLKLMALPP 593
            YGFQWRHFGARY++MHADYTGQGFDQLLDVIDKIKN PDDRRIILSAWNPSDLKLMALPP
Sbjct: 372  YGFQWRHFGARYSDMHADYTGQGFDQLLDVIDKIKNNPDDRRIILSAWNPSDLKLMALPP 431

Query: 592  CHMFAQFYVANGELSCQMYQRSADMGLGVPFNIASYSLLTCMIAHVCGLVPGDFVHVIGD 413
            CHMFAQFYVA+GELSCQMYQRSADMGLGVPFNIASY+LLTCMIAHVC LVPGDFVHV GD
Sbjct: 432  CHMFAQFYVAHGELSCQMYQRSADMGLGVPFNIASYALLTCMIAHVCNLVPGDFVHVFGD 491

Query: 412  AHVYKTHVSPLQEQLKKLPRPFPILKINPHKKDIDSFVAADFELKNYEPHPKLEMKMAV 236
            AHVY THV PLQEQL+KLP+PFPILKINP KK+IDSFVAADF+L  Y+PH K++MKMAV
Sbjct: 492  AHVYCTHVRPLQEQLQKLPKPFPILKINPEKKNIDSFVAADFKLIGYDPHNKIDMKMAV 550


>ref|XP_010664716.1| PREDICTED: putative bifunctional dihydrofolate reductase-thymidylate
            synthase isoform X1 [Vitis vinifera]
 ref|XP_010664717.1| PREDICTED: putative bifunctional dihydrofolate reductase-thymidylate
            synthase isoform X1 [Vitis vinifera]
 ref|XP_010664718.1| PREDICTED: putative bifunctional dihydrofolate reductase-thymidylate
            synthase isoform X1 [Vitis vinifera]
 ref|XP_019072178.1| PREDICTED: putative bifunctional dihydrofolate reductase-thymidylate
            synthase isoform X1 [Vitis vinifera]
 ref|XP_019072179.1| PREDICTED: putative bifunctional dihydrofolate reductase-thymidylate
            synthase isoform X1 [Vitis vinifera]
 ref|XP_019072180.1| PREDICTED: putative bifunctional dihydrofolate reductase-thymidylate
            synthase isoform X1 [Vitis vinifera]
 ref|XP_019072181.1| PREDICTED: putative bifunctional dihydrofolate reductase-thymidylate
            synthase isoform X1 [Vitis vinifera]
 ref|XP_019072182.1| PREDICTED: putative bifunctional dihydrofolate reductase-thymidylate
            synthase isoform X1 [Vitis vinifera]
 ref|XP_019072183.1| PREDICTED: putative bifunctional dihydrofolate reductase-thymidylate
            synthase isoform X1 [Vitis vinifera]
 ref|XP_019072184.1| PREDICTED: putative bifunctional dihydrofolate reductase-thymidylate
            synthase isoform X1 [Vitis vinifera]
 ref|XP_019072185.1| PREDICTED: putative bifunctional dihydrofolate reductase-thymidylate
            synthase isoform X1 [Vitis vinifera]
 ref|XP_019072186.1| PREDICTED: putative bifunctional dihydrofolate reductase-thymidylate
            synthase isoform X1 [Vitis vinifera]
 ref|XP_019072187.1| PREDICTED: putative bifunctional dihydrofolate reductase-thymidylate
            synthase isoform X1 [Vitis vinifera]
          Length = 570

 Score =  852 bits (2200), Expect = 0.0
 Identities = 411/556 (73%), Positives = 469/556 (84%), Gaps = 3/556 (0%)
 Frame = -1

Query: 1894 SVSSFVCSFETLKPFVAQRFCRRYLVMGGDSIEFFSNGNTNTQPIPQRTYQVVVAATPDM 1715
            S S+    F  L     +R    Y V+ GDS   + NG+    P+PQRTYQVVVAAT  M
Sbjct: 18   SASALSRLFTVLNVIAKRRVQTSYSVLSGDSAMSYPNGDARVHPVPQRTYQVVVAATHKM 77

Query: 1714 GIGKDGKLPWRLPGDLKFFKEITASTSDPNKKNVVMMGRKTWESIPPQFRPLPGRLNVIL 1535
            GIGKDGKLPW LP DLKFFKE+T +TSDP KKN V+MGRKTWESIP  +RPLPGRLNV+L
Sbjct: 78   GIGKDGKLPWNLPSDLKFFKELTMTTSDPGKKNAVVMGRKTWESIPLNYRPLPGRLNVVL 137

Query: 1534 TRSGSSDVPAAENVIFCGSLPSALKLLEEPPYSFSIEKVFLIGGGQILREALNAPECDAI 1355
            TRSGS D    ENV+ CGS+PSALKLL E PY  SI+KVF+IGGGQILREALNAP CDAI
Sbjct: 138  TRSGSFDNATVENVVICGSMPSALKLLAESPYCLSIDKVFVIGGGQILREALNAPGCDAI 197

Query: 1354 HITEIKTYIDCDTFIPPIDMSLYQPWYSSSLIEENGVPYCFVTYVRLNTNGGHLDS---G 1184
            HIT+I+T I+CDTFIP ID S++ PWYSS  + EN + Y FVTYVR+ ++   L+S    
Sbjct: 198  HITKIETSIECDTFIPTIDTSVFHPWYSSVPLLENNILYSFVTYVRVRSSA--LESFALS 255

Query: 1183 HGISCNGSTSRPKGLKLSDFTFLPKFIFEKHEEFLYLRLVQDIISNGNNKDDRTGTGTLS 1004
             G++ NG  S P  LK+  FTFLPK IFE+H+EF+YLR +++IIS+G +K D+TGTGT+S
Sbjct: 256  SGVNFNGG-SVPNKLKIQGFTFLPKMIFERHDEFMYLRQLKEIISSGAHKADKTGTGTVS 314

Query: 1003 KFGCQMRFNLRKSFPLLTTKRVFWRGVVEELLWFISGSTNAKILQEKGIHIWDGNASREF 824
            KFGCQMRFNLR SFPLLTTKRVFWRGVVEELLWFISGSTNAK+LQ+K IHIWDGNASRE+
Sbjct: 315  KFGCQMRFNLRLSFPLLTTKRVFWRGVVEELLWFISGSTNAKVLQKKDIHIWDGNASREY 374

Query: 823  LDSIGLTDREEGDLGPVYGFQWRHFGARYTNMHADYTGQGFDQLLDVIDKIKNKPDDRRI 644
            LDSIGLTDREEGDLGP+YGFQWRHFGARYTNMHADY G+GFDQLLDVIDKIKNKPDDRRI
Sbjct: 375  LDSIGLTDREEGDLGPIYGFQWRHFGARYTNMHADYMGKGFDQLLDVIDKIKNKPDDRRI 434

Query: 643  ILSAWNPSDLKLMALPPCHMFAQFYVANGELSCQMYQRSADMGLGVPFNIASYSLLTCMI 464
            ILS+WNPSDLKLMALPPCHMFAQFYVANGELSCQMYQRSADMGLGVPFNIASY+LLTCMI
Sbjct: 435  ILSSWNPSDLKLMALPPCHMFAQFYVANGELSCQMYQRSADMGLGVPFNIASYALLTCMI 494

Query: 463  AHVCGLVPGDFVHVIGDAHVYKTHVSPLQEQLKKLPRPFPILKINPHKKDIDSFVAADFE 284
            AHVCG++PGDF+ +IGDAH+YKTH+ PL+EQL+KLP+PFPILKINP KKDI+SFVAADFE
Sbjct: 495  AHVCGILPGDFILIIGDAHIYKTHIRPLEEQLQKLPKPFPILKINPQKKDIESFVAADFE 554

Query: 283  LKNYEPHPKLEMKMAV 236
            L  Y PH K+EMKM+V
Sbjct: 555  LIGYNPHQKIEMKMSV 570


>ref|XP_021628142.1| bifunctional dihydrofolate reductase-thymidylate synthase-like
            isoform X1 [Manihot esculenta]
 gb|OAY37221.1| hypothetical protein MANES_11G084400 [Manihot esculenta]
          Length = 527

 Score =  849 bits (2194), Expect = 0.0
 Identities = 408/527 (77%), Positives = 454/527 (86%)
 Frame = -1

Query: 1816 MGGDSIEFFSNGNTNTQPIPQRTYQVVVAATPDMGIGKDGKLPWRLPGDLKFFKEITAST 1637
            M G+     SNGN N QP  QRTYQVVVAAT DMGIGKDGKLPWRLP DLKFFK++T +T
Sbjct: 1    MAGEFKANLSNGNANVQPAAQRTYQVVVAATRDMGIGKDGKLPWRLPSDLKFFKDVTMTT 60

Query: 1636 SDPNKKNVVMMGRKTWESIPPQFRPLPGRLNVILTRSGSSDVPAAENVIFCGSLPSALKL 1457
            SD  KKN V+MGRKTWESIP + RPLPGRLNV+LTRSGS D+  AENV+ CGSL SAL+L
Sbjct: 61   SDSGKKNAVIMGRKTWESIPLEHRPLPGRLNVVLTRSGSFDIATAENVVMCGSLNSALEL 120

Query: 1456 LEEPPYSFSIEKVFLIGGGQILREALNAPECDAIHITEIKTYIDCDTFIPPIDMSLYQPW 1277
            L   PY  SIEK F+IGGGQILREALNAP CDAIH+TEI+T IDCDTFIP +D S++QPW
Sbjct: 121  LAASPYCLSIEKAFVIGGGQILREALNAPGCDAIHMTEIETNIDCDTFIPTVDSSVFQPW 180

Query: 1276 YSSSLIEENGVPYCFVTYVRLNTNGGHLDSGHGISCNGSTSRPKGLKLSDFTFLPKFIFE 1097
            YSS  + EN + YCF TYVR+ ++    +  +    + S S     ++  F+FLPK +FE
Sbjct: 181  YSSFPMVENSIRYCFATYVRVRSSVVESNGENNGLSSDSGSENSKFEVKKFSFLPKMVFE 240

Query: 1096 KHEEFLYLRLVQDIISNGNNKDDRTGTGTLSKFGCQMRFNLRKSFPLLTTKRVFWRGVVE 917
            +HEEFLYLRLVQDIIS+G  KDDRTGTGTLSKFGCQMRFNLRK+FPLLTTK+VFWRGVVE
Sbjct: 241  RHEEFLYLRLVQDIISDGVLKDDRTGTGTLSKFGCQMRFNLRKTFPLLTTKKVFWRGVVE 300

Query: 916  ELLWFISGSTNAKILQEKGIHIWDGNASREFLDSIGLTDREEGDLGPVYGFQWRHFGARY 737
            ELLWFISGSTNAK+LQEKGIHIWDGNASR++LDSIGL DREEGDLGPVYGFQWRHFGARY
Sbjct: 301  ELLWFISGSTNAKVLQEKGIHIWDGNASRDYLDSIGLKDREEGDLGPVYGFQWRHFGARY 360

Query: 736  TNMHADYTGQGFDQLLDVIDKIKNKPDDRRIILSAWNPSDLKLMALPPCHMFAQFYVANG 557
            T+MHADYTGQGFDQLLDVIDKIK+ PDDRRIILSAWNPSDLKLMALPPCHMFAQFYVANG
Sbjct: 361  TDMHADYTGQGFDQLLDVIDKIKSNPDDRRIILSAWNPSDLKLMALPPCHMFAQFYVANG 420

Query: 556  ELSCQMYQRSADMGLGVPFNIASYSLLTCMIAHVCGLVPGDFVHVIGDAHVYKTHVSPLQ 377
            ELSCQMYQRSADMGLGVPFNIASY+LLTCMIAHVC LVPGDF+HV GDAHVY +HV PLQ
Sbjct: 421  ELSCQMYQRSADMGLGVPFNIASYALLTCMIAHVCNLVPGDFIHVFGDAHVYSSHVRPLQ 480

Query: 376  EQLKKLPRPFPILKINPHKKDIDSFVAADFELKNYEPHPKLEMKMAV 236
            EQL+KLP+PFPIL INP KK+IDSFVAADF+L  Y+PH K+EMKMAV
Sbjct: 481  EQLQKLPKPFPILMINPEKKNIDSFVAADFKLIGYDPHHKIEMKMAV 527


>ref|XP_020533467.1| bifunctional dihydrofolate reductase-thymidylate synthase 1 [Jatropha
            curcas]
 gb|KDP41765.1| hypothetical protein JCGZ_26783 [Jatropha curcas]
          Length = 525

 Score =  849 bits (2193), Expect = 0.0
 Identities = 411/529 (77%), Positives = 457/529 (86%), Gaps = 2/529 (0%)
 Frame = -1

Query: 1816 MGGDSIEFFSNGNTNTQPIPQRTYQVVVAATPDMGIGKDGKLPWRLPGDLKFFKEITAST 1637
            M GDS    SNG  N Q  P+RTYQVVVAAT DMGIGK+GKLPWRLP DLKFFK++T +T
Sbjct: 1    MAGDSKASLSNGTANIQSDPRRTYQVVVAATRDMGIGKEGKLPWRLPSDLKFFKDVTLTT 60

Query: 1636 SDPNKKNVVMMGRKTWESIPPQFRPLPGRLNVILTRSGSSDVPAAENVIFCGSLPSALKL 1457
            SD  +KN V+MGRKTWESIP + RPLPGRLNV+LTRSGS D+  AENV+ CGSL SAL+L
Sbjct: 61   SDSGRKNAVIMGRKTWESIPLEHRPLPGRLNVVLTRSGSFDIATAENVVICGSLTSALEL 120

Query: 1456 LEEPPYSFSIEKVFLIGGGQILREALNAPECDAIHITEIKTYIDCDTFIPPIDMSLYQPW 1277
            L   PY  SIEKVF+IGGGQILRE+LNAP CDAIHITEI+T IDCDTFIP ID S++QPW
Sbjct: 121  LAASPYCLSIEKVFIIGGGQILRESLNAPGCDAIHITEIETSIDCDTFIPKIDSSVFQPW 180

Query: 1276 YSSSLIEENGVPYCFVTYVRLNTNGGHLDSGHGISCNGSTSRPKGLK--LSDFTFLPKFI 1103
            YSS  I EN V YCF TYVR+  +       HG   NG +S    +K  +  F+FLPK +
Sbjct: 181  YSSFPIVENNVRYCFATYVRVRVSAVE---SHGQD-NGLSSDNSYIKFEVKKFSFLPKMV 236

Query: 1102 FEKHEEFLYLRLVQDIISNGNNKDDRTGTGTLSKFGCQMRFNLRKSFPLLTTKRVFWRGV 923
            FE+HEEFLYLRLVQDIIS+GN KDDRTGTGTLSKFGCQMRFNLR++FPLLTTK+VFWRGV
Sbjct: 237  FERHEEFLYLRLVQDIISDGNLKDDRTGTGTLSKFGCQMRFNLRRTFPLLTTKKVFWRGV 296

Query: 922  VEELLWFISGSTNAKILQEKGIHIWDGNASREFLDSIGLTDREEGDLGPVYGFQWRHFGA 743
            VEELLWFISGSTN K+LQEKGIHIWDGNASR++LD IGL DREEGDLGPVYGFQWRHFGA
Sbjct: 297  VEELLWFISGSTNCKVLQEKGIHIWDGNASRDYLDGIGLKDREEGDLGPVYGFQWRHFGA 356

Query: 742  RYTNMHADYTGQGFDQLLDVIDKIKNKPDDRRIILSAWNPSDLKLMALPPCHMFAQFYVA 563
            RYT+MHADYTGQGFDQLLDVIDKIKN PDDRRIILSAWNPSDLKLMALPPCHMFAQFYVA
Sbjct: 357  RYTDMHADYTGQGFDQLLDVIDKIKNNPDDRRIILSAWNPSDLKLMALPPCHMFAQFYVA 416

Query: 562  NGELSCQMYQRSADMGLGVPFNIASYSLLTCMIAHVCGLVPGDFVHVIGDAHVYKTHVSP 383
            NGELSCQMYQRSADMGLGVPFNIASY+LLTC+++HVC LVPGDFVHV+GDAHVY+THV P
Sbjct: 417  NGELSCQMYQRSADMGLGVPFNIASYALLTCIVSHVCDLVPGDFVHVLGDAHVYRTHVRP 476

Query: 382  LQEQLKKLPRPFPILKINPHKKDIDSFVAADFELKNYEPHPKLEMKMAV 236
            LQEQL+K P+PFPILKINP KK+IDSFVAADF+L  Y+PH K+EMKMA+
Sbjct: 477  LQEQLQKPPKPFPILKINPEKKNIDSFVAADFKLIGYDPHQKIEMKMAI 525


>ref|XP_004289633.1| PREDICTED: bifunctional dihydrofolate reductase-thymidylate
            synthase-like [Fragaria vesca subsp. vesca]
 ref|XP_011457700.1| PREDICTED: bifunctional dihydrofolate reductase-thymidylate
            synthase-like [Fragaria vesca subsp. vesca]
          Length = 528

 Score =  848 bits (2192), Expect = 0.0
 Identities = 406/518 (78%), Positives = 454/518 (87%), Gaps = 1/518 (0%)
 Frame = -1

Query: 1786 NGNTNTQPIPQRTYQVVVAATPDMGIGKDGKLPWRLPGDLKFFKEITASTSDPNKKNVVM 1607
            NGN NTQ  PQRTYQVVVAAT  MGIGKDGKLPWRLP DLKFFKE+T +TSDP KKN ++
Sbjct: 13   NGNGNTQLNPQRTYQVVVAATRQMGIGKDGKLPWRLPSDLKFFKEVTVTTSDPGKKNAII 72

Query: 1606 MGRKTWESIPPQFRPLPGRLNVILTRSGSSDVPAAENVIFCGSLPSALKLLEEPPYSFSI 1427
            MGRKTWESIPP+ RPLPGRLNV+LTRSGS D+  AENV+ CGS+ SAL+LL   PY  SI
Sbjct: 73   MGRKTWESIPPEHRPLPGRLNVVLTRSGSFDIATAENVVICGSIASALELLAASPYCLSI 132

Query: 1426 EKVFLIGGGQILREALNAPECDAIHITEIKTYIDCDTFIPPIDMSLYQPWYSSSLIEENG 1247
            +KVFLIGGGQILREALN P CDAIHITEI+T I+CDT IP ID +++QPWYSS    EN 
Sbjct: 133  DKVFLIGGGQILREALNGPGCDAIHITEIETNIECDTCIPAIDSAVFQPWYSSFPKVENS 192

Query: 1246 VPYCFVTYVRLNTNG-GHLDSGHGISCNGSTSRPKGLKLSDFTFLPKFIFEKHEEFLYLR 1070
            + + F TYVR+ ++  G L   + ++CN  +   K +K   F FLPK IFEKHEE++YL 
Sbjct: 193  IRHSFTTYVRVRSSEVGSLCENNDLNCNSRSDSIKEVK--KFPFLPKMIFEKHEEYMYLN 250

Query: 1069 LVQDIISNGNNKDDRTGTGTLSKFGCQMRFNLRKSFPLLTTKRVFWRGVVEELLWFISGS 890
            LVQ+IIS+G +KDDRTGTGTLSKFGCQMRFNLR++FPLLTTK+VFWRGVVEELLWF+SGS
Sbjct: 251  LVQEIISDGTSKDDRTGTGTLSKFGCQMRFNLRRTFPLLTTKKVFWRGVVEELLWFLSGS 310

Query: 889  TNAKILQEKGIHIWDGNASREFLDSIGLTDREEGDLGPVYGFQWRHFGARYTNMHADYTG 710
            TNAK+LQEKGIHIWDGNASR++LDSIGLT REEGDLGPVYGFQWRHFGARYT+MHADYTG
Sbjct: 311  TNAKVLQEKGIHIWDGNASRDYLDSIGLTGREEGDLGPVYGFQWRHFGARYTDMHADYTG 370

Query: 709  QGFDQLLDVIDKIKNKPDDRRIILSAWNPSDLKLMALPPCHMFAQFYVANGELSCQMYQR 530
            QGFDQLLDVIDKIKN PDDRRIILSAWNPSDLKLMALPPCHMFAQFYVA GELSCQMYQR
Sbjct: 371  QGFDQLLDVIDKIKNNPDDRRIILSAWNPSDLKLMALPPCHMFAQFYVAKGELSCQMYQR 430

Query: 529  SADMGLGVPFNIASYSLLTCMIAHVCGLVPGDFVHVIGDAHVYKTHVSPLQEQLKKLPRP 350
            SADMGLGVPFNIASY+LLTCMIAHVC LVPGDFVHV+GDAHVY+TH+ PL+EQLKKLP+P
Sbjct: 431  SADMGLGVPFNIASYALLTCMIAHVCDLVPGDFVHVLGDAHVYRTHIRPLEEQLKKLPKP 490

Query: 349  FPILKINPHKKDIDSFVAADFELKNYEPHPKLEMKMAV 236
            FPILKINP KK+IDSFVAADFEL  Y+PH K+EMKMAV
Sbjct: 491  FPILKINPEKKNIDSFVAADFELSGYDPHEKIEMKMAV 528


>ref|XP_010664720.1| PREDICTED: putative bifunctional dihydrofolate reductase-thymidylate
            synthase isoform X5 [Vitis vinifera]
          Length = 549

 Score =  848 bits (2192), Expect = 0.0
 Identities = 406/533 (76%), Positives = 462/533 (86%), Gaps = 3/533 (0%)
 Frame = -1

Query: 1825 YLVMGGDSIEFFSNGNTNTQPIPQRTYQVVVAATPDMGIGKDGKLPWRLPGDLKFFKEIT 1646
            Y V+ GDS   + NG+    P+PQRTYQVVVAAT  MGIGKDGKLPW LP DLKFFKE+T
Sbjct: 20   YSVLSGDSAMSYPNGDARVHPVPQRTYQVVVAATHKMGIGKDGKLPWNLPSDLKFFKELT 79

Query: 1645 ASTSDPNKKNVVMMGRKTWESIPPQFRPLPGRLNVILTRSGSSDVPAAENVIFCGSLPSA 1466
             +TSDP KKN V+MGRKTWESIP  +RPLPGRLNV+LTRSGS D    ENV+ CGS+PSA
Sbjct: 80   MTTSDPGKKNAVVMGRKTWESIPLNYRPLPGRLNVVLTRSGSFDNATVENVVICGSMPSA 139

Query: 1465 LKLLEEPPYSFSIEKVFLIGGGQILREALNAPECDAIHITEIKTYIDCDTFIPPIDMSLY 1286
            LKLL E PY  SI+KVF+IGGGQILREALNAP CDAIHIT+I+T I+CDTFIP ID S++
Sbjct: 140  LKLLAESPYCLSIDKVFVIGGGQILREALNAPGCDAIHITKIETSIECDTFIPTIDTSVF 199

Query: 1285 QPWYSSSLIEENGVPYCFVTYVRLNTNGGHLDS---GHGISCNGSTSRPKGLKLSDFTFL 1115
             PWYSS  + EN + Y FVTYVR+ ++   L+S     G++ NG  S P  LK+  FTFL
Sbjct: 200  HPWYSSVPLLENNILYSFVTYVRVRSSA--LESFALSSGVNFNGG-SVPNKLKIQGFTFL 256

Query: 1114 PKFIFEKHEEFLYLRLVQDIISNGNNKDDRTGTGTLSKFGCQMRFNLRKSFPLLTTKRVF 935
            PK IFE+H+EF+YLR +++IIS+G +K D+TGTGT+SKFGCQMRFNLR SFPLLTTKRVF
Sbjct: 257  PKMIFERHDEFMYLRQLKEIISSGAHKADKTGTGTVSKFGCQMRFNLRLSFPLLTTKRVF 316

Query: 934  WRGVVEELLWFISGSTNAKILQEKGIHIWDGNASREFLDSIGLTDREEGDLGPVYGFQWR 755
            WRGVVEELLWFISGSTNAK+LQ+K IHIWDGNASRE+LDSIGLTDREEGDLGP+YGFQWR
Sbjct: 317  WRGVVEELLWFISGSTNAKVLQKKDIHIWDGNASREYLDSIGLTDREEGDLGPIYGFQWR 376

Query: 754  HFGARYTNMHADYTGQGFDQLLDVIDKIKNKPDDRRIILSAWNPSDLKLMALPPCHMFAQ 575
            HFGARYTNMHADY G+GFDQLLDVIDKIKNKPDDRRIILS+WNPSDLKLMALPPCHMFAQ
Sbjct: 377  HFGARYTNMHADYMGKGFDQLLDVIDKIKNKPDDRRIILSSWNPSDLKLMALPPCHMFAQ 436

Query: 574  FYVANGELSCQMYQRSADMGLGVPFNIASYSLLTCMIAHVCGLVPGDFVHVIGDAHVYKT 395
            FYVANGELSCQMYQRSADMGLGVPFNIASY+LLTCMIAHVCG++PGDF+ +IGDAH+YKT
Sbjct: 437  FYVANGELSCQMYQRSADMGLGVPFNIASYALLTCMIAHVCGILPGDFILIIGDAHIYKT 496

Query: 394  HVSPLQEQLKKLPRPFPILKINPHKKDIDSFVAADFELKNYEPHPKLEMKMAV 236
            H+ PL+EQL+KLP+PFPILKINP KKDI+SFVAADFEL  Y PH K+EMKM+V
Sbjct: 497  HIRPLEEQLQKLPKPFPILKINPQKKDIESFVAADFELIGYNPHQKIEMKMSV 549


>ref|XP_024166629.1| bifunctional dihydrofolate reductase-thymidylate synthase-like [Rosa
            chinensis]
 gb|PRQ23823.1| putative dihydrofolate reductase, Thymidylate synthase [Rosa
            chinensis]
          Length = 529

 Score =  845 bits (2184), Expect = 0.0
 Identities = 403/518 (77%), Positives = 454/518 (87%), Gaps = 1/518 (0%)
 Frame = -1

Query: 1786 NGNTNTQPIPQRTYQVVVAATPDMGIGKDGKLPWRLPGDLKFFKEITASTSDPNKKNVVM 1607
            NGN NTQ  PQRTYQVVVAAT +MGIGKDGKLPW+LP DLKFFK++T +TSDP KKN ++
Sbjct: 13   NGNGNTQLNPQRTYQVVVAATREMGIGKDGKLPWKLPSDLKFFKDVTVTTSDPGKKNAII 72

Query: 1606 MGRKTWESIPPQFRPLPGRLNVILTRSGSSDVPAAENVIFCGSLPSALKLLEEPPYSFSI 1427
            MGRKTWESIPP+ RPLPGRLNV+LTRSGS D+  AENV+ CGS+ SAL+LL   PY  SI
Sbjct: 73   MGRKTWESIPPEHRPLPGRLNVVLTRSGSFDIATAENVVICGSMTSALELLAASPYCLSI 132

Query: 1426 EKVFLIGGGQILREALNAPECDAIHITEIKTYIDCDTFIPPIDMSLYQPWYSSSLIEENG 1247
            +KVFLIGGGQILREALN P CDAIHITEI+T I+CDTFIP ID +++QPWYSS    EN 
Sbjct: 133  DKVFLIGGGQILREALNGPGCDAIHITEIETNIECDTFIPAIDSTVFQPWYSSFPKVENS 192

Query: 1246 VPYCFVTYVRLNTNG-GHLDSGHGISCNGSTSRPKGLKLSDFTFLPKFIFEKHEEFLYLR 1070
            + Y F TYVR+ ++  G L   + ++CN  +   K  ++  F+FLPK IFEKHEE++YL 
Sbjct: 193  IRYSFTTYVRVRSSEVGSLCENNDLNCNSRSDSIK-CEVKKFSFLPKMIFEKHEEYMYLN 251

Query: 1069 LVQDIISNGNNKDDRTGTGTLSKFGCQMRFNLRKSFPLLTTKRVFWRGVVEELLWFISGS 890
            LVQDI+S+G +KDDRTGTGTLSKFGCQMRFNLR+SFPLLTTK+VFWRGVVEELLWF+SGS
Sbjct: 252  LVQDILSDGTSKDDRTGTGTLSKFGCQMRFNLRRSFPLLTTKKVFWRGVVEELLWFLSGS 311

Query: 889  TNAKILQEKGIHIWDGNASREFLDSIGLTDREEGDLGPVYGFQWRHFGARYTNMHADYTG 710
            TNAK+LQEKGI IWDGNASR++LDSIGLT REEGDLGPVYGFQWRHFGARYT+MHADYTG
Sbjct: 312  TNAKVLQEKGIRIWDGNASRDYLDSIGLTGREEGDLGPVYGFQWRHFGARYTDMHADYTG 371

Query: 709  QGFDQLLDVIDKIKNKPDDRRIILSAWNPSDLKLMALPPCHMFAQFYVANGELSCQMYQR 530
            QGFDQLLDVIDKIKN PDDRRIILSAWNPSDLKLMALPPCHMFAQFYVA GELSCQMYQR
Sbjct: 372  QGFDQLLDVIDKIKNNPDDRRIILSAWNPSDLKLMALPPCHMFAQFYVAKGELSCQMYQR 431

Query: 529  SADMGLGVPFNIASYSLLTCMIAHVCGLVPGDFVHVIGDAHVYKTHVSPLQEQLKKLPRP 350
            SADMGLGVPFNIASY+LLTCMIAHVC LVPGDFVHV+GDAH+Y+TH+ PLQEQL+KLP+P
Sbjct: 432  SADMGLGVPFNIASYALLTCMIAHVCDLVPGDFVHVLGDAHIYRTHIRPLQEQLQKLPKP 491

Query: 349  FPILKINPHKKDIDSFVAADFELKNYEPHPKLEMKMAV 236
             PILKINP KK+IDSFVAADFEL  Y PH K+EMKMAV
Sbjct: 492  LPILKINPDKKNIDSFVAADFELIGYNPHEKIEMKMAV 529


>ref|XP_011037491.1| PREDICTED: bifunctional dihydrofolate reductase-thymidylate synthase
            1-like [Populus euphratica]
 ref|XP_011037492.1| PREDICTED: bifunctional dihydrofolate reductase-thymidylate synthase
            1-like [Populus euphratica]
          Length = 528

 Score =  845 bits (2183), Expect = 0.0
 Identities = 406/529 (76%), Positives = 461/529 (87%), Gaps = 2/529 (0%)
 Frame = -1

Query: 1816 MGGDSIEFFSNGNTNTQ-PIPQRTYQVVVAATPDMGIGKDGKLPWRLPGDLKFFKEITAS 1640
            M GDS+   SNGN NTQ P PQ+TYQVVVAAT DMGIGKDGKLPW+LP DLKFFK++T +
Sbjct: 1    MSGDSVANLSNGNANTQQPAPQKTYQVVVAATKDMGIGKDGKLPWKLPSDLKFFKDLTLT 60

Query: 1639 TSDPNKKNVVMMGRKTWESIPPQFRPLPGRLNVILTRSGSSDVPAAENVIFCGSLPSALK 1460
            T D  KKN V+MGRKTWESIP + RPLPGRLNV+LTRSGS D+  AENV+ CGS+ SAL+
Sbjct: 61   TMDSGKKNAVIMGRKTWESIPLEHRPLPGRLNVVLTRSGSFDIATAENVVICGSMSSALE 120

Query: 1459 LLEEPPYSFSIEKVFLIGGGQILREALNAPECDAIHITEIKTYIDCDTFIPPIDMSLYQP 1280
            LL   PY  SIEKVF+IGGGQILRE+LNAP CDAIHITEI+   DCDTFIP ID S++QP
Sbjct: 121  LLAASPYCLSIEKVFVIGGGQILRESLNAPGCDAIHITEIEMDFDCDTFIPAIDTSVFQP 180

Query: 1279 WYSSSLIEENGVPYCFVTYVRLNTNGGHLDS-GHGISCNGSTSRPKGLKLSDFTFLPKFI 1103
            WYSS    EN + +CF TYVR+ ++     S  +G + +G++   K  ++  F+FLPK +
Sbjct: 181  WYSSFPNVENDIRHCFTTYVRVRSSTIESHSQNNGENSDGNSENSK-FEVMKFSFLPKMV 239

Query: 1102 FEKHEEFLYLRLVQDIISNGNNKDDRTGTGTLSKFGCQMRFNLRKSFPLLTTKRVFWRGV 923
            FE+HEE+LYLR+VQDIIS+GN KDDRTGTGTLSKFGCQMRFNLRK+FPLLTTK+VFWRGV
Sbjct: 240  FERHEEYLYLRMVQDIISDGNLKDDRTGTGTLSKFGCQMRFNLRKNFPLLTTKKVFWRGV 299

Query: 922  VEELLWFISGSTNAKILQEKGIHIWDGNASREFLDSIGLTDREEGDLGPVYGFQWRHFGA 743
            VEELLWFISGST+AK+LQEKGIHIWDGNASR++LDSIGL DREEGDLGPVYGFQWRHFGA
Sbjct: 300  VEELLWFISGSTSAKVLQEKGIHIWDGNASRDYLDSIGLKDREEGDLGPVYGFQWRHFGA 359

Query: 742  RYTNMHADYTGQGFDQLLDVIDKIKNKPDDRRIILSAWNPSDLKLMALPPCHMFAQFYVA 563
            RYT+MHADYTGQGFDQLLDVIDKIKN P+DRRII+SAWNPSDLKLMALPPCHMFAQFYVA
Sbjct: 360  RYTDMHADYTGQGFDQLLDVIDKIKNNPNDRRIIISAWNPSDLKLMALPPCHMFAQFYVA 419

Query: 562  NGELSCQMYQRSADMGLGVPFNIASYSLLTCMIAHVCGLVPGDFVHVIGDAHVYKTHVSP 383
            NGELSCQMYQRSADMGLGVPFNIASY+LLTC+IAHVC L+PGDFVHVIGDAHVY TH+ P
Sbjct: 420  NGELSCQMYQRSADMGLGVPFNIASYALLTCIIAHVCDLIPGDFVHVIGDAHVYHTHIRP 479

Query: 382  LQEQLKKLPRPFPILKINPHKKDIDSFVAADFELKNYEPHPKLEMKMAV 236
            LQEQL+KLP+PFPILKIN  KKDID+FVAADF+L  Y+PH K+EMKMAV
Sbjct: 480  LQEQLRKLPKPFPILKINSEKKDIDTFVAADFKLIGYDPHQKIEMKMAV 528