BLASTX 2.2.26 [Sep-21-2011]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= Rehmannia29_contig00005084
         (3029 letters)

Database: All non-redundant GenBank CDS
translations+PDB+SwissProt+PIR+PRF excluding environmental samples
from WGS projects 
           149,584,005 sequences; 54,822,741,787 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

ref|XP_011093631.1| DNA topoisomerase 1 [Sesamum indicum] >gi|11...  1288   0.0  
gb|PIN13662.1| DNA topoisomerase I [Handroanthus impetiginosus]      1235   0.0  
ref|XP_012845487.1| PREDICTED: DNA topoisomerase 1-like [Erythra...  1071   0.0  
gb|EYU30724.1| hypothetical protein MIMGU_mgv1a001121mg [Erythra...  1071   0.0  
gb|KZV21640.1| DNA topoisomerase 1-like [Dorcoceras hygrometricum]   1060   0.0  
emb|CDP13767.1| unnamed protein product [Coffea canephora]           1024   0.0  
dbj|BAG31376.1| topoisomerase I [Camptotheca acuminata]              1008   0.0  
dbj|BAG31377.1| topoisomerase I [Catharanthus roseus]                 991   0.0  
dbj|BAK32958.1| topoisomerase I [Ophiorrhiza pedunculata]             990   0.0  
ref|XP_022846035.1| DNA topoisomerase 1 beta-like [Olea europaea...   989   0.0  
dbj|BAK32962.1| topoisomerase I [Ophiorrhiza trichocarpon var. g...   988   0.0  
dbj|BAG31375.1| topoisomerase I [Ophiorrhiza japonica]                983   0.0  
dbj|BAK32960.1| topoisomerase I [Ophiorrhiza pseudofasciculata]       983   0.0  
ref|XP_010266803.1| PREDICTED: DNA topoisomerase 1 alpha-like [N...   932   0.0  
ref|XP_023553297.1| DNA topoisomerase 1 beta-like [Cucurbita pep...   927   0.0  
gb|KVI01089.1| DNA breaking-rejoining enzyme, catalytic core [Cy...   926   0.0  
ref|XP_023007686.1| DNA topoisomerase 1 beta-like [Cucurbita max...   920   0.0  
ref|XP_022932254.1| DNA topoisomerase 1 beta-like [Cucurbita mos...   918   0.0  
gb|PON81509.1| DNA topoisomerase I [Trema orientalis]                 903   0.0  
ref|XP_017215919.1| PREDICTED: DNA topoisomerase 1-like [Daucus ...   877   0.0  

>ref|XP_011093631.1| DNA topoisomerase 1 [Sesamum indicum]
 ref|XP_020553411.1| DNA topoisomerase 1 [Sesamum indicum]
          Length = 893

 Score = 1288 bits (3333), Expect = 0.0
 Identities = 655/822 (79%), Positives = 690/822 (83%)
 Frame = -2

Query: 2467 MAVEACDKQKLXXXXXXXXEPLVFKRXXXXXXXXXXXSEAKKSLSQKHDRQLGRPAPDVR 2288
            MA+E+C+ QKL        EPLVFKR           SE K+ LSQKHDR L RP+PDVR
Sbjct: 1    MAIESCNDQKLMDDMDEDDEPLVFKRSSSSAKQSQGNSETKRPLSQKHDRPLNRPSPDVR 60

Query: 2287 SQNGQSTIVKKSKTVPLSKTPPVKYPLTSPKSSNTSGKALALKSPEVDSKPSTSVTDKSN 2108
             QNGQST+++KSKTVP S+TPP++ PL SPKSSN+S KALA++  EVD +PSTSVTD+SN
Sbjct: 61   PQNGQSTMIQKSKTVPSSRTPPLRSPLASPKSSNSSAKALAVRPREVDPRPSTSVTDESN 120

Query: 2107 SVKHQIKDEKLSTEATGEPNEDSQDSEDDKPLSARLPAGLSKVNSNHAKKSPNTSTLSQK 1928
            SVKHQIKDEK ST+ATG  NEDS+DSEDDKPLSARLPAGLSKVNSNHA K PN  T  QK
Sbjct: 121  SVKHQIKDEKPSTKATGGLNEDSEDSEDDKPLSARLPAGLSKVNSNHANKGPNALTSVQK 180

Query: 1927 RRIPIPEDSDDEIPLSSKFQVKSNAGESINRSSNSGERKPLLSKYDQNGSASTERKPSTN 1748
             +IP PEDSDDEIPLSSKFQVKSNAGES NR S SGERKPLL+KYDQNGSAS ERKPST 
Sbjct: 181  TKIPKPEDSDDEIPLSSKFQVKSNAGESTNRPSISGERKPLLAKYDQNGSASAERKPSTI 240

Query: 1747 LKKRPGDGVKTTDESYLKKPKLSEAATPHKNKEASIKAEMREEDDEDHVPISHRMXXXXX 1568
            LKKRP DGVK+  ESYLKKPKLS+A+TP+K KE SIK EM++EDDEDHVPIS R+     
Sbjct: 241  LKKRPADGVKSAGESYLKKPKLSDASTPNKTKETSIKDEMKDEDDEDHVPISQRIKQQTS 300

Query: 1567 XXXXXXXXKNITKPIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSGEGQKWTTLVHNGVI 1388
                    KN+TKPI                             SGEGQKWTTLVHNGVI
Sbjct: 301  SDKKSSSAKNMTKPISASAKKTSKKPKKVMKNSKYSKSSKVPPSSGEGQKWTTLVHNGVI 360

Query: 1387 FPPPYKPHGVKMLYKGKPVDLTPEQEEVATMYAVMLETDYMNKPKFKENFMADWRKILGK 1208
            FPPPYKPHGVKMLYKGKPVDLTPEQEEVATMYAVML+TDYMNKPKFKENFMADWRKILGK
Sbjct: 361  FPPPYKPHGVKMLYKGKPVDLTPEQEEVATMYAVMLDTDYMNKPKFKENFMADWRKILGK 420

Query: 1207 NHTIQSLEHCDFTPIYEWHXXXXXXXXXXXXXXXXXXXXXXXXXXXKYMWAIVNGVKEKV 1028
            NH IQSLEHCDFTPIYEWH                           KYMWAIVNGVKEKV
Sbjct: 421  NHVIQSLEHCDFTPIYEWHQKEKEKKKQMTAEEKKALKEEKLKQEEKYMWAIVNGVKEKV 480

Query: 1027 GNFRVEPPGLFRGRGEHPKMGKLKKRIRPSDITINIGKDAPIPECPIPGESWKEIRHDNT 848
            GNFRVEPPGLFRGRGEHPKMGKLKKRIRPSDITINIGKDAPIPECPIPGESWKEIRHDNT
Sbjct: 481  GNFRVEPPGLFRGRGEHPKMGKLKKRIRPSDITINIGKDAPIPECPIPGESWKEIRHDNT 540

Query: 847  VTWLAYWNDPINPKEFKYVFLAASSTLKGQSDKEKYEKARLLKDYILGIRAAYTKDFTSK 668
            VTWLAYWNDPINPKEFKYVFLAASSTLKGQSDKEKYEKARLLKDYI GIRAAYTKDFT+K
Sbjct: 541  VTWLAYWNDPINPKEFKYVFLAASSTLKGQSDKEKYEKARLLKDYIHGIRAAYTKDFTNK 600

Query: 667  DPAKRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVEPVPPNTLKFDFLGKDS 488
            DP K+QIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVEPVPPN LKFDFLGKDS
Sbjct: 601  DPTKKQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVEPVPPNILKFDFLGKDS 660

Query: 487  IRYQNEVEVETAVFKAIQQFRSGKKGGDDLFDRLDTSKLNAHLKELMPGLTAKVFRTYNA 308
            IRYQNEVEVET VFKAIQQFRSGKKG DD+FDRLDTSKLNAHLKELMPGLTAKVFRTYNA
Sbjct: 661  IRYQNEVEVETPVFKAIQQFRSGKKGSDDMFDRLDTSKLNAHLKELMPGLTAKVFRTYNA 720

Query: 307  SITLDDMLSRETRGGDVAEKVVVYQHANKEVAIICNHQRTVSKSHSAQMLRLNEKIEELK 128
            SITLDD LSRET+GGDVAEKVVVYQHANKEVAIICNHQRTVSKSHSAQM RLNEKIEELK
Sbjct: 721  SITLDDKLSRETKGGDVAEKVVVYQHANKEVAIICNHQRTVSKSHSAQMTRLNEKIEELK 780

Query: 127  GVVEELQTDLARAKKGKPPLKSADGKPKRNLNPDALERKIAQ 2
            GV+EELQTDLARAKKGKPPLKSADGKPKRNLNPDALE+KIAQ
Sbjct: 781  GVLEELQTDLARAKKGKPPLKSADGKPKRNLNPDALEKKIAQ 822


>gb|PIN13662.1| DNA topoisomerase I [Handroanthus impetiginosus]
          Length = 895

 Score = 1235 bits (3195), Expect = 0.0
 Identities = 631/824 (76%), Positives = 677/824 (82%), Gaps = 2/824 (0%)
 Frame = -2

Query: 2467 MAVEACDKQKLXXXXXXXXEPLVFKRXXXXXXXXXXXSEAKKSLSQKHDRQLGRPAPDVR 2288
            MAVEACDKQKL        EPLVFKR           SE KKSLSQKHDRQLG+PAPD+R
Sbjct: 1    MAVEACDKQKLMDDMDDDDEPLVFKRSSSAAKQNQSVSETKKSLSQKHDRQLGKPAPDIR 60

Query: 2287 SQNGQSTIVKKSKTVPLSKTPPVKYPLTSPKSSNTSGKALALKSPEVDSKPSTSVTDKSN 2108
            SQNGQST+V+KSK    SKTPPV+ PL SPKSSN+S K+ A+KS  V+SKPSTSV D+SN
Sbjct: 61   SQNGQSTMVEKSKMASSSKTPPVRSPLASPKSSNSSAKSFAVKSSGVNSKPSTSVADESN 120

Query: 2107 SVKHQIKDEKLSTEATGEPNEDSQDSEDDKPLSARLPAGLSKVNSNHAKKSPNTSTLSQK 1928
            SVK Q +D++  TEAT E NE+S+DS+DDKPL+ARL AG SK+NSNHA K PN S L QK
Sbjct: 121  SVKQQSRDKRPLTEATAELNEESEDSDDDKPLTARLSAGFSKINSNHANKGPNASILGQK 180

Query: 1927 RRIPIPEDSDDEIPLSSKFQVKSNAGESINRSSNSGERKPLLSKYDQNGSASTERKPSTN 1748
             +IP  EDSDDEIPLSSKFQVKSNAG+S  +S  SG RKPL +K D NG  S ERKPS++
Sbjct: 181  PKIPKSEDSDDEIPLSSKFQVKSNAGDSSKKSPTSGGRKPLSAKCDHNGLGSPERKPSSS 240

Query: 1747 --LKKRPGDGVKTTDESYLKKPKLSEAATPHKNKEASIKAEMREEDDEDHVPISHRMXXX 1574
              LKKRP DGVK+  ES+LK+PKLS+A+  +KNKE SIKAE++EEDDEDHVPIS RM   
Sbjct: 241  TILKKRPADGVKSAGESHLKRPKLSDASASNKNKETSIKAELKEEDDEDHVPISARMKKS 300

Query: 1573 XXXXXXXXXXKNITKPIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSGEGQKWTTLVHNG 1394
                      KNITKP+                             SGEGQKWTTLVHNG
Sbjct: 301  TSSDKKPSSSKNITKPVSSLSKKINKKSKKVTKKSEYSKSSKVPPGSGEGQKWTTLVHNG 360

Query: 1393 VIFPPPYKPHGVKMLYKGKPVDLTPEQEEVATMYAVMLETDYMNKPKFKENFMADWRKIL 1214
            VIFPPPYKPHGVKMLYKGKPVDLTPEQEEVATM+AVML+TDYMNKPKFKENFM DWRKIL
Sbjct: 361  VIFPPPYKPHGVKMLYKGKPVDLTPEQEEVATMFAVMLDTDYMNKPKFKENFMDDWRKIL 420

Query: 1213 GKNHTIQSLEHCDFTPIYEWHXXXXXXXXXXXXXXXXXXXXXXXXXXXKYMWAIVNGVKE 1034
            GKNH IQSLEHC+FTPIYEWH                           KYMWAIV+GVKE
Sbjct: 421  GKNHVIQSLEHCNFTPIYEWHQKEKEKKKQMSADEKKALKEEKLKQEDKYMWAIVDGVKE 480

Query: 1033 KVGNFRVEPPGLFRGRGEHPKMGKLKKRIRPSDITINIGKDAPIPECPIPGESWKEIRHD 854
            KVGNFRVEPPGLFRGRGEHPKMGKLKKRIRPSDI INIGKDAPIPECPIPGESWKE+RHD
Sbjct: 481  KVGNFRVEPPGLFRGRGEHPKMGKLKKRIRPSDIVINIGKDAPIPECPIPGESWKEVRHD 540

Query: 853  NTVTWLAYWNDPINPKEFKYVFLAASSTLKGQSDKEKYEKARLLKDYILGIRAAYTKDFT 674
            NTVTWLAYWNDPINPKEFKYVFLAASS LKGQSDKEKYEKARLLKDYI  IRA YTK+FT
Sbjct: 541  NTVTWLAYWNDPINPKEFKYVFLAASSALKGQSDKEKYEKARLLKDYIQDIRATYTKNFT 600

Query: 673  SKDPAKRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVEPVPPNTLKFDFLGK 494
            SKDP K+QIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVEPVPPN LKFDFLGK
Sbjct: 601  SKDPTKKQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVEPVPPNILKFDFLGK 660

Query: 493  DSIRYQNEVEVETAVFKAIQQFRSGKKGGDDLFDRLDTSKLNAHLKELMPGLTAKVFRTY 314
            DSIRYQNEVEVETAVF+AIQ+FR GKKGGDDLFD+LDTSKLNAHLKELMPGLTAKVFRTY
Sbjct: 661  DSIRYQNEVEVETAVFRAIQEFRRGKKGGDDLFDKLDTSKLNAHLKELMPGLTAKVFRTY 720

Query: 313  NASITLDDMLSRETRGGDVAEKVVVYQHANKEVAIICNHQRTVSKSHSAQMLRLNEKIEE 134
            NASITLDDMLSRET+GGDVAEKVVVYQ ANKEVAIICNHQRTVSKSHSAQMLRLNEKIEE
Sbjct: 721  NASITLDDMLSRETKGGDVAEKVVVYQLANKEVAIICNHQRTVSKSHSAQMLRLNEKIEE 780

Query: 133  LKGVVEELQTDLARAKKGKPPLKSADGKPKRNLNPDALERKIAQ 2
            LKGV+EELQTDLARAKKGKPPLK+ADGKPKRNLNPDALERKIAQ
Sbjct: 781  LKGVLEELQTDLARAKKGKPPLKNADGKPKRNLNPDALERKIAQ 824


>ref|XP_012845487.1| PREDICTED: DNA topoisomerase 1-like [Erythranthe guttata]
          Length = 894

 Score = 1072 bits (2771), Expect = 0.0
 Identities = 568/838 (67%), Positives = 632/838 (75%), Gaps = 16/838 (1%)
 Frame = -2

Query: 2467 MAVEAC-DKQKLXXXXXXXXEPLVFKRXXXXXXXXXXXSEAKKSLSQKHDRQLGRPAPDV 2291
            M VEA  DK  +         PLVFKR            E K S SQKH+ Q+GR + DV
Sbjct: 1    MTVEAREDKNMMEDMDDDDDAPLVFKRSGSSSKPKQSEPENKLS-SQKHNAQVGRQSSDV 59

Query: 2290 RSQNGQSTIVKKSKTVPLSKT--PPVKYPLTSPKSSNTSGKALALKSPEVDSKPSTSVTD 2117
            R QNG +   +K K+V  S +  PPV+  L SPKSSN+S KA  +KSP+V+SKPSTSV  
Sbjct: 60   RPQNGTNANAQKGKSVTSSSSMKPPVRPSLVSPKSSNSSVKASPIKSPDVNSKPSTSVVG 119

Query: 2116 KSNSVKHQIKDEKLSTEATGEPNEDSQDSEDDKPLSARLPAGLSKVNSNHAKKSPNTSTL 1937
            +S SVK  IK+E            +S+DSEDDKPLSAR  AG SK N N   K PN   L
Sbjct: 120  ESKSVKSTIKEE------------NSEDSEDDKPLSARQVAGSSKNNPNQTNK-PNAPNL 166

Query: 1936 SQKRRIPIPEDSDDEIPLSSKFQVKSNAGESINRSSNSGERKPLLS-KYDQNGSASTERK 1760
             +K  +P PEDSDDEIPLS+KFQ KSNAG S +RSS+S E+KPL++ K D+NGSASTERK
Sbjct: 167  GKKSNVPKPEDSDDEIPLSAKFQGKSNAGASTSRSSHSEEKKPLVARKPDKNGSASTERK 226

Query: 1759 PSTNLKKRPGDGVKTTDESYLKKPKLSEAATPHKNKEASIKAEMREEDDEDHVPISHRMX 1580
            PST L+KRP DGV +  +S LKKPKLS++    K+K+AS+K E++ EDDED VP+S R  
Sbjct: 227  PSTVLQKRPADGVASAGQSNLKKPKLSDSLAS-KDKKASVKPEVKAEDDEDLVPLSQRTK 285

Query: 1579 XXXXXXXXXXXXKNITKPIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXS----------- 1433
                          +TK                               +           
Sbjct: 286  KSTTPEKKPSPALKVTKSTASISKKTNNKTNSKTNSKTNKKSKQVSKDNNYSKSSKLPPS 345

Query: 1432 -GEGQKWTTLVHNGVIFPPPYKPHGVKMLYKGKPVDLTPEQEEVATMYAVMLETDYMNKP 1256
             G+GQKWTTLVHNGVIFPPPYKPHGVKMLYKGKPV+LTPEQEEVATMYAVMLETDY+ KP
Sbjct: 346  SGDGQKWTTLVHNGVIFPPPYKPHGVKMLYKGKPVNLTPEQEEVATMYAVMLETDYLKKP 405

Query: 1255 KFKENFMADWRKILGKNHTIQSLEHCDFTPIYEWHXXXXXXXXXXXXXXXXXXXXXXXXX 1076
            +FKENFM DW+KILGKNH IQSLEHCDFTPIYEWH                         
Sbjct: 406  QFKENFMTDWKKILGKNHVIQSLEHCDFTPIYEWHQREKEKKKQMSTDEKKALKEEKLKL 465

Query: 1075 XXKYMWAIVNGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIRPSDITINIGKDAPIPE 896
              KYMWA+++GV+EKVGNFRVEPPGLFRGRGEHPKMGKLK+RIRPSDITINIG+DAPIPE
Sbjct: 466  EEKYMWAVLDGVREKVGNFRVEPPGLFRGRGEHPKMGKLKRRIRPSDITINIGRDAPIPE 525

Query: 895  CPIPGESWKEIRHDNTVTWLAYWNDPINPKEFKYVFLAASSTLKGQSDKEKYEKARLLKD 716
            CPI GE WKEIRHDNTVTWLAYW+DPIN KEFKYVFLAASSTLKGQSDKEKYEKARLLKD
Sbjct: 526  CPIEGERWKEIRHDNTVTWLAYWSDPINGKEFKYVFLAASSTLKGQSDKEKYEKARLLKD 585

Query: 715  YILGIRAAYTKDFTSKDPAKRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVE 536
            YI GIR AYT+DF SKDPAK+QIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVE
Sbjct: 586  YIQGIRTAYTRDFVSKDPAKKQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVE 645

Query: 535  PVPPNTLKFDFLGKDSIRYQNEVEVETAVFKAIQQFRSGKKGGDDLFDRLDTSKLNAHLK 356
            PVPPN LKFDFLGKDSIRYQNEVEVETAVFKAIQQFRSGKKGGDDLFD+LDTSKLNAHLK
Sbjct: 646  PVPPNILKFDFLGKDSIRYQNEVEVETAVFKAIQQFRSGKKGGDDLFDKLDTSKLNAHLK 705

Query: 355  ELMPGLTAKVFRTYNASITLDDMLSRETRGGDVAEKVVVYQHANKEVAIICNHQRTVSKS 176
            ELMPGLTAKVFRTYNASITLDD LSRET+GGD+AEKVV Y HANKEVAIICNHQRTVSK+
Sbjct: 706  ELMPGLTAKVFRTYNASITLDDKLSRETKGGDLAEKVVTYNHANKEVAIICNHQRTVSKT 765

Query: 175  HSAQMLRLNEKIEELKGVVEELQTDLARAKKGKPPLKSADGKPKRNLNPDALERKIAQ 2
            HSAQMLRL+EKI+ELKGV+EEL+TDL RA+KGKP L  ADGK KRN+NP+ALERKIAQ
Sbjct: 766  HSAQMLRLDEKIDELKGVLEELKTDLGRARKGKPLLAGADGKAKRNINPEALERKIAQ 823


>gb|EYU30724.1| hypothetical protein MIMGU_mgv1a001121mg [Erythranthe guttata]
          Length = 883

 Score = 1072 bits (2771), Expect = 0.0
 Identities = 568/827 (68%), Positives = 630/827 (76%), Gaps = 5/827 (0%)
 Frame = -2

Query: 2467 MAVEAC-DKQKLXXXXXXXXEPLVFKRXXXXXXXXXXXSEAKKSLSQKHDRQLGRPAPDV 2291
            M VEA  DK  +         PLVFKR            E K S SQKH+ Q+GR + DV
Sbjct: 1    MTVEAREDKNMMEDMDDDDDAPLVFKRSGSSSKPKQSEPENKLS-SQKHNAQVGRQSSDV 59

Query: 2290 RSQNGQSTIVKKSKTVPLSKT--PPVKYPLTSPKSSNTSGKALALKSPEVDSKPSTSVTD 2117
            R QNG +   +K K+V  S +  PPV+  L SPKSSN+S KA  +KSP+V+SKPSTSV  
Sbjct: 60   RPQNGTNANAQKGKSVTSSSSMKPPVRPSLVSPKSSNSSVKASPIKSPDVNSKPSTSVVG 119

Query: 2116 KSNSVKHQIKDEKLSTEATGEPNEDSQDSEDDKPLSARLPAGLSKVNSNHAKKSPNTSTL 1937
            +S SVK  IK+E            +S+DSEDDKPLSAR  AG SK N N   K PN   L
Sbjct: 120  ESKSVKSTIKEE------------NSEDSEDDKPLSARQVAGSSKNNPNQTNK-PNAPNL 166

Query: 1936 SQKRRIPIPEDSDDEIPLSSKFQVKSNAGESINRSSNSGERKPLLS-KYDQNGSASTERK 1760
             +K  +P PEDSDDEIPLS+KFQ KSNAG S +RSS+S E+KPL++ K D+NGSASTERK
Sbjct: 167  GKKSNVPKPEDSDDEIPLSAKFQGKSNAGASTSRSSHSEEKKPLVARKPDKNGSASTERK 226

Query: 1759 PSTNLKKRPGDGVKTTDESYLKKPKLSEAATPHKNKEASIKAEMREEDDEDHVPISHRMX 1580
            PST L+KRP DGV +  +S LKKPKLS++    K+K+AS+K E++ EDDED VP+S R  
Sbjct: 227  PSTVLQKRPADGVASAGQSNLKKPKLSDSLAS-KDKKASVKPEVKAEDDEDLVPLSQRTK 285

Query: 1579 XXXXXXXXXXXXKNIT-KPIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSGEGQKWTTLV 1403
                             K                               SG+GQKWTTLV
Sbjct: 286  KSTTPEKKPSPALKTNNKTNSKTNSKTNKKSKQVSKDNNYSKSSKLPPSSGDGQKWTTLV 345

Query: 1402 HNGVIFPPPYKPHGVKMLYKGKPVDLTPEQEEVATMYAVMLETDYMNKPKFKENFMADWR 1223
            HNGVIFPPPYKPHGVKMLYKGKPV+LTPEQEEVATMYAVMLETDY+ KP+FKENFM DW+
Sbjct: 346  HNGVIFPPPYKPHGVKMLYKGKPVNLTPEQEEVATMYAVMLETDYLKKPQFKENFMTDWK 405

Query: 1222 KILGKNHTIQSLEHCDFTPIYEWHXXXXXXXXXXXXXXXXXXXXXXXXXXXKYMWAIVNG 1043
            KILGKNH IQSLEHCDFTPIYEWH                           KYMWA+++G
Sbjct: 406  KILGKNHVIQSLEHCDFTPIYEWHQREKEKKKQMSTDEKKALKEEKLKLEEKYMWAVLDG 465

Query: 1042 VKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIRPSDITINIGKDAPIPECPIPGESWKEI 863
            V+EKVGNFRVEPPGLFRGRGEHPKMGKLK+RIRPSDITINIG+DAPIPECPI GE WKEI
Sbjct: 466  VREKVGNFRVEPPGLFRGRGEHPKMGKLKRRIRPSDITINIGRDAPIPECPIEGERWKEI 525

Query: 862  RHDNTVTWLAYWNDPINPKEFKYVFLAASSTLKGQSDKEKYEKARLLKDYILGIRAAYTK 683
            RHDNTVTWLAYW+DPIN KEFKYVFLAASSTLKGQSDKEKYEKARLLKDYI GIR AYT+
Sbjct: 526  RHDNTVTWLAYWSDPINGKEFKYVFLAASSTLKGQSDKEKYEKARLLKDYIQGIRTAYTR 585

Query: 682  DFTSKDPAKRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVEPVPPNTLKFDF 503
            DF SKDPAK+QIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVEPVPPN LKFDF
Sbjct: 586  DFVSKDPAKKQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVEPVPPNILKFDF 645

Query: 502  LGKDSIRYQNEVEVETAVFKAIQQFRSGKKGGDDLFDRLDTSKLNAHLKELMPGLTAKVF 323
            LGKDSIRYQNEVEVETAVFKAIQQFRSGKKGGDDLFD+LDTSKLNAHLKELMPGLTAKVF
Sbjct: 646  LGKDSIRYQNEVEVETAVFKAIQQFRSGKKGGDDLFDKLDTSKLNAHLKELMPGLTAKVF 705

Query: 322  RTYNASITLDDMLSRETRGGDVAEKVVVYQHANKEVAIICNHQRTVSKSHSAQMLRLNEK 143
            RTYNASITLDD LSRET+GGD+AEKVV Y HANKEVAIICNHQRTVSK+HSAQMLRL+EK
Sbjct: 706  RTYNASITLDDKLSRETKGGDLAEKVVTYNHANKEVAIICNHQRTVSKTHSAQMLRLDEK 765

Query: 142  IEELKGVVEELQTDLARAKKGKPPLKSADGKPKRNLNPDALERKIAQ 2
            I+ELKGV+EEL+TDL RA+KGKP L  ADGK KRN+NP+ALERKIAQ
Sbjct: 766  IDELKGVLEELKTDLGRARKGKPLLAGADGKAKRNINPEALERKIAQ 812


>gb|KZV21640.1| DNA topoisomerase 1-like [Dorcoceras hygrometricum]
          Length = 870

 Score = 1060 bits (2741), Expect = 0.0
 Identities = 565/827 (68%), Positives = 632/827 (76%), Gaps = 5/827 (0%)
 Frame = -2

Query: 2467 MAVEACDKQK-LXXXXXXXXEPLVFKRXXXXXXXXXXXSEAKKSLSQKHDRQLGRPAPDV 2291
            MAV+A D++K L        +PLVFKR                S S KH+ + G+     
Sbjct: 1    MAVDAFDEKKSLDDVDDDDDQPLVFKR---------------SSSSSKHNLKNGQ----- 40

Query: 2290 RSQNGQSTIVKKSKTVP-LSKTPPVKYPLTSPKSSNTSGKALALKSPEVDSKPSTSVTDK 2114
            +S+NG+S+ V+K   VP  SK PP+K PLTSPKSS+++ K   +KS   +SK   S TDK
Sbjct: 41   QSRNGESSSVQKGTLVPPSSKAPPIKSPLTSPKSSSSAAKESPVKSSAANSKRPMSETDK 100

Query: 2113 SNSVKHQIKDEKLSTEATGEPNEDSQDSEDDKPLSARLPAGLSKVNSNHAKKSPNTSTLS 1934
             NSVK Q+K+E+   +A  E + D +DS DD PLSARL A  SK NSNHAK+ PN   L 
Sbjct: 101  PNSVKQQVKEEQPFAQAADETH-DLEDSGDDTPLSARLLASSSKGNSNHAKQRPNALALV 159

Query: 1933 QKRRIPIPEDSDDEIPLSSKFQVKSNAGESINRSSNSGERKPLLSKYDQNGSASTE---R 1763
            QK  IP  EDSDDE+PLSSKFQVKS+   S +RS+NS ERKP+L+K DQNGS+ST+   +
Sbjct: 160  QKNSIPKKEDSDDEMPLSSKFQVKSDVRVSTSRSNNSDERKPILNKADQNGSSSTDHSQK 219

Query: 1762 KPSTNLKKRPGDGVKTTDESYLKKPKLSEAATPHKNKEASIKAEMREEDDEDHVPISHRM 1583
            KPS  +K RP + VK    S  KKPKLS A++      A  +A+ + EDD+DHVPIS RM
Sbjct: 220  KPSIAMK-RPPNPVKVECRSPEKKPKLSNASS------AIPRAKPKAEDDDDHVPISQRM 272

Query: 1582 XXXXXXXXXXXXXKNITKPIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSGEGQKWTTLV 1403
                         K +TK +                             SGEGQKWTTLV
Sbjct: 273  KNQSSSEKKSLSVKKVTKSVSAVATKTNKISKKIVKNTKYSISSKVLPNSGEGQKWTTLV 332

Query: 1402 HNGVIFPPPYKPHGVKMLYKGKPVDLTPEQEEVATMYAVMLETDYMNKPKFKENFMADWR 1223
            HNGVIFPPPYKPHGVKMLYKGKPV LTPEQEEVATM+AVML+TDYMNKPKFKENFM DWR
Sbjct: 333  HNGVIFPPPYKPHGVKMLYKGKPVVLTPEQEEVATMFAVMLDTDYMNKPKFKENFMTDWR 392

Query: 1222 KILGKNHTIQSLEHCDFTPIYEWHXXXXXXXXXXXXXXXXXXXXXXXXXXXKYMWAIVNG 1043
            KILGKNHTIQ LE CDFTPIYEWH                           KYMWAI++G
Sbjct: 393  KILGKNHTIQKLEDCDFTPIYEWHQKEKEKKKQMSTEEKKALKEEKLKQEEKYMWAILDG 452

Query: 1042 VKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIRPSDITINIGKDAPIPECPIPGESWKEI 863
            VKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRI+PSDI INIGKDA IPECPIPGESWKEI
Sbjct: 453  VKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIQPSDIIINIGKDAAIPECPIPGESWKEI 512

Query: 862  RHDNTVTWLAYWNDPINPKEFKYVFLAASSTLKGQSDKEKYEKARLLKDYILGIRAAYTK 683
            RHDNTVTWLAYWNDPIN KEFKYVFLAASSTLKGQSDKEKYEKARLLK+YI GIRAAYTK
Sbjct: 513  RHDNTVTWLAYWNDPINQKEFKYVFLAASSTLKGQSDKEKYEKARLLKNYIQGIRAAYTK 572

Query: 682  DFTSKDPAKRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVEPVPPNTLKFDF 503
            DF+SKDP ++QIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVEPVPPN LKFDF
Sbjct: 573  DFSSKDPTRKQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVEPVPPNILKFDF 632

Query: 502  LGKDSIRYQNEVEVETAVFKAIQQFRSGKKGGDDLFDRLDTSKLNAHLKELMPGLTAKVF 323
            LGKDSIRYQNEV VETAVFKAIQQFR+GKKGGDDLFD+LDTSKLNAHLKELMPGLTAKVF
Sbjct: 633  LGKDSIRYQNEVVVETAVFKAIQQFRNGKKGGDDLFDKLDTSKLNAHLKELMPGLTAKVF 692

Query: 322  RTYNASITLDDMLSRETRGGDVAEKVVVYQHANKEVAIICNHQRTVSKSHSAQMLRLNEK 143
            RTYNASITLDDML+RET+GG+VAEK+VVYQHANKEVAIICNHQRTVSKSHSAQMLRL+EK
Sbjct: 693  RTYNASITLDDMLNRETKGGEVAEKIVVYQHANKEVAIICNHQRTVSKSHSAQMLRLDEK 752

Query: 142  IEELKGVVEELQTDLARAKKGKPPLKSADGKPKRNLNPDALERKIAQ 2
            I+ELKG +EEL+ DL+RAKKGKPPLKSADGKPKRN+NP+ALE+KIAQ
Sbjct: 753  IDELKGAMEELREDLSRAKKGKPPLKSADGKPKRNMNPEALEKKIAQ 799


>emb|CDP13767.1| unnamed protein product [Coffea canephora]
          Length = 926

 Score = 1024 bits (2647), Expect = 0.0
 Identities = 545/856 (63%), Positives = 613/856 (71%), Gaps = 34/856 (3%)
 Frame = -2

Query: 2467 MAVEACDKQKLXXXXXXXXEPLVFKRXXXXXXXXXXXSEAKKSLSQKHDRQLGRPAPDVR 2288
            MAVEAC    L         PLVFKR           SE KK  SQK D Q  R + DV 
Sbjct: 1    MAVEACSTPSLLEDSDEENAPLVFKRTSSSSKQNLSNSETKKLSSQKRDGQSSRNSSDVC 60

Query: 2287 SQNGQSTIVKKSKTVPLSKTPPVKYPLTSPKSSNTSGKALALKSPEVDSKPSTSVTDKSN 2108
              NGQS+  +  + V  +KTPP K PL+SPK++N S K   + SP  +SKPS+S +    
Sbjct: 61   PVNGQSSSAQTGRVVSSAKTPPAKSPLSSPKAANISAKTSLITSPGANSKPSSSTSATVK 120

Query: 2107 SVKHQ-----IKDEKLSTEATGEPNEDSQDSEDDKPLSARLPAGLSKVNSNHAKKSPNTS 1943
             +++      +K  K S  A  + +   +DS+DDKPL A+LP+G S+   NH  K  + S
Sbjct: 121  QLENHKNSPVVKLPKRSVSAA-KLSSTPEDSDDDKPLMAKLPSGSSRAIVNHGNKDGDGS 179

Query: 1942 TLSQKRRIPIPEDSDDEIPLSSKFQVKSNAGESINRSSNSGERKPLLSKYDQNGSASTER 1763
            +L QK  +   EDSDDE PLSS++  KSN  ESI++S N GE+K L +K  QNGSA  + 
Sbjct: 180  SLVQKPGVEEDEDSDDEKPLSSRYLSKSNLVESISKSRNPGEKKSLPAKVQQNGSALRDG 239

Query: 1762 ---KPSTNLKKRPGDGVKTTDESYLKKPKLSEAATPHKNKEASIKAEMREEDDED----- 1607
               K S+   KRP   VK++DES +KKPKLS        K+A++KAE + EDD+D     
Sbjct: 240  PVGKSSSLSNKRPPGEVKSSDESAVKKPKLSGPTAAINKKQATLKAEPKVEDDDDDILIS 299

Query: 1606 ---------------------HVPISHRMXXXXXXXXXXXXXKNITKPIXXXXXXXXXXX 1490
                                 HVPI+ RM             K + K +           
Sbjct: 300  QTAKKMFASASKPKSNDDDDDHVPITQRMKKSTTSVSQSSSVKKVAKVVSSSLKKTNKKS 359

Query: 1489 XXXXXXXXXXXXXXXXXXSGEGQKWTTLVHNGVIFPPPYKPHGVKMLYKGKPVDLTPEQE 1310
                              SGEGQKWTTLVHNGVIFPPPYKPHGVKMLYKG+PV LTPEQE
Sbjct: 360  KKIIKKSKYSKSSKVPPGSGEGQKWTTLVHNGVIFPPPYKPHGVKMLYKGQPVTLTPEQE 419

Query: 1309 EVATMYAVMLETDYMNKPKFKENFMADWRKILGKNHTIQSLEHCDFTPIYEWHXXXXXXX 1130
            EVATM+AVML+TDYM+KP+FKENF +DW++ILGKNHTIQ+LE CDF PIYEWH       
Sbjct: 420  EVATMFAVMLDTDYMSKPQFKENFFSDWKRILGKNHTIQNLEDCDFRPIYEWHQKEKEKK 479

Query: 1129 XXXXXXXXXXXXXXXXXXXXKYMWAIVNGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKR 950
                                KYMWAIV+GVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKR
Sbjct: 480  KQMTTEEKKSLKEEKLKQEEKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKR 539

Query: 949  IRPSDITINIGKDAPIPECPIPGESWKEIRHDNTVTWLAYWNDPINPKEFKYVFLAASST 770
            IRP DITINIGKDAPIPECPIPGE WKEIRHDNTVTWLA+WNDPINPKEFKYVFLAASST
Sbjct: 540  IRPRDITINIGKDAPIPECPIPGERWKEIRHDNTVTWLAFWNDPINPKEFKYVFLAASST 599

Query: 769  LKGQSDKEKYEKARLLKDYILGIRAAYTKDFTSKDPAKRQIAVATYLIDKLALRAGNEKD 590
            LKGQSDKEKYEKARLLKDYI GIR AYTKDF SKDP K+QIAVATYLIDKLALRAGNEKD
Sbjct: 600  LKGQSDKEKYEKARLLKDYIHGIRTAYTKDFASKDPMKKQIAVATYLIDKLALRAGNEKD 659

Query: 589  DDEADTVGCCTLKVENVEPVPPNTLKFDFLGKDSIRYQNEVEVETAVFKAIQQFRSGKKG 410
            DDEADTVGCCTLKVENVEPVPPN LKFDFLGKDSIRYQNEVEVE+ VFKAIQQFRSGK+G
Sbjct: 660  DDEADTVGCCTLKVENVEPVPPNILKFDFLGKDSIRYQNEVEVESGVFKAIQQFRSGKEG 719

Query: 409  GDDLFDRLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSRETRGGDVAEKVVVYQH 230
             +DLFD+LDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSR+T GGDV EKVVVYQ 
Sbjct: 720  SEDLFDKLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSRKTNGGDVLEKVVVYQQ 779

Query: 229  ANKEVAIICNHQRTVSKSHSAQMLRLNEKIEELKGVVEELQTDLARAKKGKPPLKSADGK 50
            ANKEVAIICNHQRTVSK+HSAQM RLNEKIEELKGV+EEL+TDL+RAKKGKPPLK+ADGK
Sbjct: 780  ANKEVAIICNHQRTVSKTHSAQMSRLNEKIEELKGVLEELKTDLSRAKKGKPPLKNADGK 839

Query: 49   PKRNLNPDALERKIAQ 2
            PKRNLNP+ALERKIAQ
Sbjct: 840  PKRNLNPEALERKIAQ 855


>dbj|BAG31376.1| topoisomerase I [Camptotheca acuminata]
          Length = 894

 Score = 1008 bits (2607), Expect = 0.0
 Identities = 541/832 (65%), Positives = 612/832 (73%), Gaps = 10/832 (1%)
 Frame = -2

Query: 2467 MAVEACDKQKLXXXXXXXXEPLVFKRXXXXXXXXXXXSEAKKSLSQKHDRQLGRPAPDVR 2288
            MAV+AC K+K+        EPLVFKR           S+ KKS SQ++D Q GR   DV 
Sbjct: 1    MAVQACVKEKMMDEIDEDDEPLVFKRSNATSKHNQLNSDTKKS-SQRYDGQSGRQVSDVP 59

Query: 2287 SQNGQSTIVKKSKTVPLSKTPPVKYPLTSPKSSNTSGKALALKSPEVDSKPSTSVTDKSN 2108
            S NGQS+   K KT  LS    +K P+ SPK+S +  KA  + +P+V S  S+    K +
Sbjct: 60   STNGQSSSASKGKTTKLSS---MKSPIASPKASTSFAKASPVANPKVSS--SSDDRSKHS 114

Query: 2107 SVKHQIKDEKLSTEATGEPNEDSQDSEDDKPLSARLPAGLSKVNSNHAKKSPNTSTLSQK 1928
            S ++ I   K   E      E   DSED+KPLSARL  GL+K +SN+A K    S+ +  
Sbjct: 115  SKQNTINVVKEEKELVNPAAEPYGDSEDEKPLSARLFTGLTKGSSNNANKGLINSSPAS- 173

Query: 1927 RRIPIP--------EDSDDEIPLSSKFQVKSNAGESINRSSNSGERKPLLSKYDQNGSAS 1772
              +P+P        +DSDDEIPLSSKF++K+NAG S  +S  S + K L+S + QNGS +
Sbjct: 174  --LPVPKPEINRYSDDSDDEIPLSSKFRLKANAGTSTVKSYESDDNKTLVSNFQQNGSIN 231

Query: 1771 TERKPSTNLKKRPGDGVKTTDESYLKKPKLSEAATPHKNKEASIKAEMREED-DEDHVPI 1595
               K S  + KRP   VK++ +S +KKPKLS+A+TP  NK+AS KAE + +D D+DHVPI
Sbjct: 232  RGSKSSIKVNKRPLGEVKSSVQSSVKKPKLSDASTPVNNKQASKKAEPKADDSDDDHVPI 291

Query: 1594 SHRMXXXXXXXXXXXXXKN-ITKPIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSGEGQK 1418
            S RM             K  +TK +                             SGEG+K
Sbjct: 292  SQRMKKSATSGNKSSTAKQKVTKVVSSSMKKASKKFKKVVKKSKYSKSSKVPPSSGEGKK 351

Query: 1417 WTTLVHNGVIFPPPYKPHGVKMLYKGKPVDLTPEQEEVATMYAVMLETDYMNKPKFKENF 1238
            W TLVHNGVIFPPPYKPHGVKMLYKGKPVDLTPEQEEVATM+AVML+TDYM K KFKENF
Sbjct: 352  WNTLVHNGVIFPPPYKPHGVKMLYKGKPVDLTPEQEEVATMFAVMLDTDYMTKSKFKENF 411

Query: 1237 MADWRKILGKNHTIQSLEHCDFTPIYEWHXXXXXXXXXXXXXXXXXXXXXXXXXXXKYMW 1058
            M DWRKILGKNH IQ+LE CDFTPIYEWH                           KYMW
Sbjct: 412  MDDWRKILGKNHVIQNLEDCDFTPIYEWHQREKEKKKKMTAEEKKVLKEERLKQEEKYMW 471

Query: 1057 AIVNGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIRPSDITINIGKDAPIPECPIPGE 878
            AIVNGVKEKVGNFRVEPP LFRGRGEHPKMGKLKK IRPSDITINIGKDAPIPECPIPGE
Sbjct: 472  AIVNGVKEKVGNFRVEPPSLFRGRGEHPKMGKLKKCIRPSDITINIGKDAPIPECPIPGE 531

Query: 877  SWKEIRHDNTVTWLAYWNDPINPKEFKYVFLAASSTLKGQSDKEKYEKARLLKDYILGIR 698
            SWKEIRHDNTVTWLA+WNDPI P+EFKYVFLAASS+LKGQSDKEKYEKARLLKD+I GIR
Sbjct: 532  SWKEIRHDNTVTWLAFWNDPIKPREFKYVFLAASSSLKGQSDKEKYEKARLLKDFIQGIR 591

Query: 697  AAYTKDFTSKDPAKRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVEPVPPNT 518
            AAYTKDF SKD  KRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVEP PP+ 
Sbjct: 592  AAYTKDFASKDITKRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVEPKPPSI 651

Query: 517  LKFDFLGKDSIRYQNEVEVETAVFKAIQQFRSGKKGGDDLFDRLDTSKLNAHLKELMPGL 338
            LKFDFLGKDSIRYQNEVEVE  V+KAIQQFR+GK+GGDDLFD+LDTSKLNAHLK LMPGL
Sbjct: 652  LKFDFLGKDSIRYQNEVEVELPVYKAIQQFRTGKRGGDDLFDKLDTSKLNAHLKGLMPGL 711

Query: 337  TAKVFRTYNASITLDDMLSRETRGGDVAEKVVVYQHANKEVAIICNHQRTVSKSHSAQML 158
            TAKVFRTYNASITLD+MLSRET+GG+VAEK+VVYQHANKEVAIICNHQRTVSKSH AQM 
Sbjct: 712  TAKVFRTYNASITLDEMLSRETKGGNVAEKIVVYQHANKEVAIICNHQRTVSKSHPAQMT 771

Query: 157  RLNEKIEELKGVVEELQTDLARAKKGKPPLKSADGKPKRNLNPDALERKIAQ 2
            RLN KI+ELKG+++ LQTDLARAKKGKPPL+ ADGKPKRNL P+ALERKI Q
Sbjct: 772  RLNGKIDELKGILDGLQTDLARAKKGKPPLEDADGKPKRNLTPEALERKIGQ 823


>dbj|BAG31377.1| topoisomerase I [Catharanthus roseus]
          Length = 910

 Score =  991 bits (2563), Expect = 0.0
 Identities = 537/848 (63%), Positives = 599/848 (70%), Gaps = 26/848 (3%)
 Frame = -2

Query: 2467 MAVEACDKQKLXXXXXXXXEPLVFKRXXXXXXXXXXXSEAKKSLSQKHDRQLGRPAPDVR 2288
            MAVEAC    L        EP+VFKR           SE +K  SQK D Q  R   D R
Sbjct: 1    MAVEACPTPNLRDDMDEDDEPIVFKRNNSASKQSQTNSETRKVSSQKRDGQSVRQIYDSR 60

Query: 2287 SQNGQSTIVKKSKTVPLSK---------TPP-----VKYPLTSPKSSNTSGKALALKSPE 2150
              NG+S+  +K + VP SK         +PP     VK PL+SPK S +S K   + S  
Sbjct: 61   PANGESSSGQKGRMVPPSKPSQVKSPLSSPPSKPSQVKSPLSSPKVSTSSAKKSPVSSLP 120

Query: 2149 VDSKPSTSVTDKSNSVKHQ-----IKDEKLST-EATGEPNEDSQDSEDDKPLSARLPAGL 1988
             +SKPSTS + K            IK+EK S          DS+DS+D KPLS R  A  
Sbjct: 121  ANSKPSTSGSFKVKPFNQHKSATVIKEEKSSPLRLASAIINDSEDSDDGKPLSLRHSASS 180

Query: 1987 SKVNSNHAKKSPNTSTLSQKRRIPIPEDSDDEIPLSSKFQVKSNAGESINRSSNSGERKP 1808
            SK N+N   K  +          P  EDSDDE PLSS+F +KS  GES +++ +S + KP
Sbjct: 181  SKGNTNQVSKEGSK---------PENEDSDDEKPLSSRFPLKSGVGESTSKAYDSDDDKP 231

Query: 1807 LLSKYDQNGSASTERKP---STNLKKRPGDGVKTTDESYLKKPKLSEAATPHKNKEASIK 1637
            L  K   NGSA  + +P   S    KRP   +K++++  +KKPKLS    P   K+AS+K
Sbjct: 232  LAKKLQHNGSAMRDGQPNKYSNMSNKRPPGDIKSSNQLSVKKPKLSSVTAPTNKKQASVK 291

Query: 1636 AEMR-EEDDEDHVPISHRMXXXXXXXXXXXXXKNITKPIXXXXXXXXXXXXXXXXXXXXX 1460
             E + E+DD+DH+PIS R+             K  TK +                     
Sbjct: 292  PEPKAEDDDDDHLPISQRIKKSPTSESKSSSIKKTTKVVSSSVKKVNKKSKKVMKNSKYS 351

Query: 1459 XXXXXXXXSGEGQKWTTLVHNGVIFPPPYKPHGVKMLYKGKPVDLTPEQEEVATMYAVML 1280
                    SGEG+KW  L HNGVIFPPPYKPHG+KMLYKGKPVDLTPEQEEVATM+AVML
Sbjct: 352  KSSKVPPSSGEGKKWNKLEHNGVIFPPPYKPHGIKMLYKGKPVDLTPEQEEVATMFAVML 411

Query: 1279 ETDYMNKPKFKENFMADWRKILGKNHTIQSLEHCDFTPIYEWHXXXXXXXXXXXXXXXXX 1100
            +TDYMNKP+FKENF  DW+KILGKNH IQ+LE+CDF+PIYEWH                 
Sbjct: 412  DTDYMNKPRFKENFFGDWKKILGKNHVIQNLENCDFSPIYEWHQSEKEKKKQMTTEEKKA 471

Query: 1099 XXXXXXXXXXKYMWAIVNGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIRPSDITINI 920
                      KYMWA V+G KEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIRP DITINI
Sbjct: 472  LKEEKLKQEEKYMWAWVDGKKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIRPCDITINI 531

Query: 919  GKDAPIPECPIPGESWKEIRHDNTVTWLAYWNDPINPKEFKYVFLAASSTLKGQSDKEKY 740
            GKDAPIPECP+PGE WKE+RHDNTVTWLA+WNDPINPKEFKYVFLAASSTLKG SDKEKY
Sbjct: 532  GKDAPIPECPVPGERWKEVRHDNTVTWLAFWNDPINPKEFKYVFLAASSTLKGLSDKEKY 591

Query: 739  EKARLLKDYILGIRAAYTKDFTSKDPAKRQIAVATYLIDKLALRAGNEKDDDEADTVGCC 560
            EKARLLKDYI GIRAAYTKDF SKDP K+QIAVATYLIDKLALRAGNEKDDDEADTVGCC
Sbjct: 592  EKARLLKDYIQGIRAAYTKDFASKDPTKKQIAVATYLIDKLALRAGNEKDDDEADTVGCC 651

Query: 559  TLKVENVEPVPPNTLKFDFLGKDSIRYQNEVEVETAVFKAIQQFRSGKKGGDDLFDRLDT 380
            TLKVENVEPVPPN LKFDFLGKDSIRYQNEVEVE AVFKAIQQFRSGK+G  DLFD LDT
Sbjct: 652  TLKVENVEPVPPNILKFDFLGKDSIRYQNEVEVEAAVFKAIQQFRSGKEGSSDLFDLLDT 711

Query: 379  SKLNAHLKELMPGLTAKVFRTYNASITLDDMLSRETRGGDVAEKVVVYQHANKEVAIICN 200
            SKLNAHLKELMPGLTAKVFRTYNASITLDDMLSRET+GGDVAEKVVVYQHANKEVAIICN
Sbjct: 712  SKLNAHLKELMPGLTAKVFRTYNASITLDDMLSRETKGGDVAEKVVVYQHANKEVAIICN 771

Query: 199  HQRTVSKSHSAQMLRLNEKIEELKGVVEELQTDLARAKKGKPPLKS--ADGKPKRNLNPD 26
            HQRTVSKSHSAQMLRLNEKIEELK VVEEL++DL+R KKGKPPLKS  ADGKPKRNLNP+
Sbjct: 772  HQRTVSKSHSAQMLRLNEKIEELKAVVEELKSDLSRVKKGKPPLKSKNADGKPKRNLNPE 831

Query: 25   ALERKIAQ 2
            +LE+KIAQ
Sbjct: 832  SLEKKIAQ 839


>dbj|BAK32958.1| topoisomerase I [Ophiorrhiza pedunculata]
          Length = 920

 Score =  990 bits (2560), Expect = 0.0
 Identities = 531/855 (62%), Positives = 601/855 (70%), Gaps = 33/855 (3%)
 Frame = -2

Query: 2467 MAVEACDKQKLXXXXXXXXEPLVFKRXXXXXXXXXXXSEAKKSLSQKHDRQLGRPAPDVR 2288
            MAVEAC    L         P++FKR           SE KK   QKH  Q      DVR
Sbjct: 1    MAVEACTTTNLMEDMEDDEGPVIFKRSNPASKQNQANSEKKKLSLQKHVGQSAVHTSDVR 60

Query: 2287 SQNGQSTIVKKSKTVPLSKTPPVKYPLTSPKSSNTSGKALALKSPEVDSKPSTSVTDKSN 2108
              NG+++  +K +  P +KTPPVK PL+SPK+SN+S KA  + SP  +SKPS S T  + 
Sbjct: 61   PANGENSSAQKGRIQPSAKTPPVKSPLSSPKASNSSAKASPITSPGANSKPSASATSTAK 120

Query: 2107 SVKHQIKD----EKLSTEATGEPNEDSQDSEDDKPLSARLPAGLSKVNSNHAKKSPNTST 1940
               H        E   +    + N +S+ S+D+KPLSAR     SK  SNHA K    S 
Sbjct: 121  QQNHHKSSAAFIEPKPSVPAAKANSNSESSDDEKPLSARTFGCSSKGKSNHANKEGGDSC 180

Query: 1939 LSQKRRIPIPEDSDDEIPLSSKFQVKSNAGESINRSSNSGERKPLLSKYDQNGSASTE-- 1766
              ++  I   EDS+DE PLS +F  KS+ GES ++S +S E+KPL +K   NGSAS +  
Sbjct: 181  SIRRPVIEESEDSEDEKPLSRRFTSKSSLGESTSKSYDSDEKKPLAAKVQPNGSASRDSP 240

Query: 1765 -RKPSTNLKKRPGDGVKTTDESYLKKPKLSEAATPHKNKEASIKAEMREEDDE------- 1610
              K ++   KRP   VK+ ++S LKKPKLS   T   NK+A++K E + EDD+       
Sbjct: 241  MNKSASLSNKRPPGEVKSLNQSSLKKPKLSSPITSISNKQAAVKPEPKAEDDDDNIPLSQ 300

Query: 1609 -----------------DHVPISHRMXXXXXXXXXXXXXKN-ITKPIXXXXXXXXXXXXX 1484
                             D+VPIS R+                 +  +             
Sbjct: 301  RGKKSQTATSKPKDEDDDNVPISQRIKKSPASVSKSSAPVKKASTVVSPSLKKVNKKSKK 360

Query: 1483 XXXXXXXXXXXXXXXXSGEGQKWTTLVHNGVIFPPPYKPHGVKMLYKGKPVDLTPEQEEV 1304
                            SGEGQKWTTLVHNGVIFPPPYKPHGVKMLYK +P+ LTPEQEEV
Sbjct: 361  VIKKTAYTKSSKVPPGSGEGQKWTTLVHNGVIFPPPYKPHGVKMLYKRQPITLTPEQEEV 420

Query: 1303 ATMYAVMLETDYMNKPKFKENFMADWRKILGKNHTIQSLEHCDFTPIYEWHXXXXXXXXX 1124
            ATM+AVML+TDYMNKP+FKENF +DW+K+LGKNHTIQ+LE CDF PIYEWH         
Sbjct: 421  ATMFAVMLDTDYMNKPRFKENFFSDWKKMLGKNHTIQNLEDCDFGPIYEWHQQEKEKKKQ 480

Query: 1123 XXXXXXXXXXXXXXXXXXKYMWAIVNGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIR 944
                              KYMWAIV+GVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIR
Sbjct: 481  MTTEEKKALKEEKLQQEEKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIR 540

Query: 943  PSDITINIGKDAPIPECPIPGESWKEIRHDNTVTWLAYWNDPINPKEFKYVFLAASSTLK 764
            P DITINIGKDAPIPECPIPGE WKE+R+DNTVTWLAYWNDPIN KEFKYVFLAASSTLK
Sbjct: 541  PRDITINIGKDAPIPECPIPGERWKEVRNDNTVTWLAYWNDPINQKEFKYVFLAASSTLK 600

Query: 763  GQSDKEKYEKARLLKDYILGIRAAYTKDFTS-KDPAKRQIAVATYLIDKLALRAGNEKDD 587
            GQSDKEKYEKARLLKDYI GIRAAYTKDFT+ KDP K+QIAVATYLIDKLALRAGNEKDD
Sbjct: 601  GQSDKEKYEKARLLKDYIHGIRAAYTKDFTNNKDPMKKQIAVATYLIDKLALRAGNEKDD 660

Query: 586  DEADTVGCCTLKVENVEPVPPNTLKFDFLGKDSIRYQNEVEVETAVFKAIQQFRSGKKGG 407
            DEADTVGCCTLKVENVEPVPPN LKFDFLGKDSIRYQNEV+VE AVFKAI QFRSGK+G 
Sbjct: 661  DEADTVGCCTLKVENVEPVPPNILKFDFLGKDSIRYQNEVQVEPAVFKAIHQFRSGKEGS 720

Query: 406  DDLFDRLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSRETRGGDVAEKVVVYQHA 227
            +DLFDRLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLS++T GG+VAEKVVVYQHA
Sbjct: 721  EDLFDRLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSKKTNGGEVAEKVVVYQHA 780

Query: 226  NKEVAIICNHQRTVSKSHSAQMLRLNEKIEELKGVVEELQTDLARAKKGKPPLKSADGKP 47
            NKEVAIICNHQRTVSKSHSAQM RLNEKI+ELK  +EEL+TDL+RAKKGKP  K ADGKP
Sbjct: 781  NKEVAIICNHQRTVSKSHSAQMSRLNEKIDELKTALEELKTDLSRAKKGKPLSKGADGKP 840

Query: 46   KRNLNPDALERKIAQ 2
            KRNLNP+ALERKIAQ
Sbjct: 841  KRNLNPEALERKIAQ 855


>ref|XP_022846035.1| DNA topoisomerase 1 beta-like [Olea europaea var. sylvestris]
          Length = 771

 Score =  989 bits (2557), Expect = 0.0
 Identities = 508/701 (72%), Positives = 556/701 (79%), Gaps = 4/701 (0%)
 Frame = -2

Query: 2092 IKDEKLSTEATGEPNEDSQDSEDDKPLSARLPAGLSKVNSNHAKKSPNTSTLSQKRRIPI 1913
            +K EK ST    EPN DS+DSEDDKPLSARL   LSK NSN+A K  N S L QK  IP 
Sbjct: 1    MKVEKPSTGPAAEPN-DSEDSEDDKPLSARLSTSLSKNNSNNASKGSNASRLGQKPSIPK 59

Query: 1912 PEDSDDEIPLSSKFQVKSNAGESINRSSNSGERKPLLSKYDQNGSA---STERKPSTNLK 1742
             EDSDDE PLS K Q+KSN G S  +S +S E+  L +K +QNGS    S  +KPST L 
Sbjct: 60   QEDSDDEKPLSHKVQLKSNVGSSTRKSYDSDEKMHLAAKNNQNGSPLQDSGSKKPSTILS 119

Query: 1741 KRPGDGVKTTDESYLKKPKLSEAATPHKNKEASIKAEMR-EEDDEDHVPISHRMXXXXXX 1565
            KRP   V +  +S +KK K+S A+    NK+AS+KAE + E+DD+DH+PIS RM      
Sbjct: 120  KRPASEVNSAGQSSIKKHKISNASVLINNKQASVKAEPKVEDDDDDHIPISQRMKKPAAS 179

Query: 1564 XXXXXXXKNITKPIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSGEGQKWTTLVHNGVIF 1385
                   K +TK +                             SGEGQKWTTL+HNGVIF
Sbjct: 180  DKKISAIKKVTKVVSSSLNKTNKNSKKVVKKSQYSKSSKVPPGSGEGQKWTTLIHNGVIF 239

Query: 1384 PPPYKPHGVKMLYKGKPVDLTPEQEEVATMYAVMLETDYMNKPKFKENFMADWRKILGKN 1205
            PPPY+ HGVKMLYKGKPV+LTPEQEEVATM+AVML+T+YMNKPKFKENFM+DWRKILGKN
Sbjct: 240  PPPYQSHGVKMLYKGKPVNLTPEQEEVATMFAVMLDTEYMNKPKFKENFMSDWRKILGKN 299

Query: 1204 HTIQSLEHCDFTPIYEWHXXXXXXXXXXXXXXXXXXXXXXXXXXXKYMWAIVNGVKEKVG 1025
            H IQ+LE CDFTPIYEWH                           KYMWAIV+GVKEKVG
Sbjct: 300  HIIQNLEDCDFTPIYEWHQKEKEKKKQMTTEEKKVIKEEKMKQEEKYMWAIVDGVKEKVG 359

Query: 1024 NFRVEPPGLFRGRGEHPKMGKLKKRIRPSDITINIGKDAPIPECPIPGESWKEIRHDNTV 845
            NFRVEPPGLFRGRGEHPKMGKLK+RIRPSDITINIGKDAPIPECPIPGESWKEIRHDNTV
Sbjct: 360  NFRVEPPGLFRGRGEHPKMGKLKRRIRPSDITINIGKDAPIPECPIPGESWKEIRHDNTV 419

Query: 844  TWLAYWNDPINPKEFKYVFLAASSTLKGQSDKEKYEKARLLKDYILGIRAAYTKDFTSKD 665
            TWLA+WNDPINPKE KYVFLAASSTLKGQSDKEKYEK+RLLKDYI GIRA+YTKDF SKD
Sbjct: 420  TWLAFWNDPINPKEIKYVFLAASSTLKGQSDKEKYEKSRLLKDYIQGIRASYTKDFASKD 479

Query: 664  PAKRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVEPVPPNTLKFDFLGKDSI 485
            P K+QIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVEP+PPN LKFDFLGKDSI
Sbjct: 480  PTKKQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVEPMPPNILKFDFLGKDSI 539

Query: 484  RYQNEVEVETAVFKAIQQFRSGKKGGDDLFDRLDTSKLNAHLKELMPGLTAKVFRTYNAS 305
            RYQNEVEVE+AVFKAIQQFRSGKK  DDLFD+LDTSKLNAHLKELMPGLTAKVFRTYNAS
Sbjct: 540  RYQNEVEVESAVFKAIQQFRSGKKAADDLFDKLDTSKLNAHLKELMPGLTAKVFRTYNAS 599

Query: 304  ITLDDMLSRETRGGDVAEKVVVYQHANKEVAIICNHQRTVSKSHSAQMLRLNEKIEELKG 125
            ITLD+MLS++T+ GDVAE +VVYQHANKEVAIICNHQRTVSKSHSAQMLRLNEKIEELK 
Sbjct: 600  ITLDEMLSKDTKAGDVAENIVVYQHANKEVAIICNHQRTVSKSHSAQMLRLNEKIEELKV 659

Query: 124  VVEELQTDLARAKKGKPPLKSADGKPKRNLNPDALERKIAQ 2
            V+EEL TDL RAKKGKPPLKSADGK KRNLNP+ALE+KIAQ
Sbjct: 660  VLEELTTDLVRAKKGKPPLKSADGKTKRNLNPEALEKKIAQ 700


>dbj|BAK32962.1| topoisomerase I [Ophiorrhiza trichocarpon var. glabra]
          Length = 920

 Score =  988 bits (2554), Expect = 0.0
 Identities = 530/855 (61%), Positives = 601/855 (70%), Gaps = 33/855 (3%)
 Frame = -2

Query: 2467 MAVEACDKQKLXXXXXXXXEPLVFKRXXXXXXXXXXXSEAKKSLSQKHDRQLGRPAPDVR 2288
            MAVEAC    L         P++FKR           SE KK   Q+H  Q      DVR
Sbjct: 1    MAVEACTTTNLMEDMEDDEGPVIFKRSNPASKQNQANSEKKKLSLQRHVGQSAVHTSDVR 60

Query: 2287 SQNGQSTIVKKSKTVPLSKTPPVKYPLTSPKSSNTSGKALALKSPEVDSKPSTSVTDKSN 2108
              NG+++  +K +  P +KTPPVK PL+SPK+SN+S KA  + S   +SKPS S T  + 
Sbjct: 61   PANGENSSAQKGRIQPSAKTPPVKSPLSSPKASNSSAKASPITSAGANSKPSASATSTAK 120

Query: 2107 SVKHQIKD----EKLSTEATGEPNEDSQDSEDDKPLSARLPAGLSKVNSNHAKKSPNTST 1940
               H        E   +    + N +S+ S+D+KPLSAR     SK  SNHA K    S 
Sbjct: 121  QQNHHKSSAAFIEPKPSVPAAKANSNSESSDDEKPLSARTFGCSSKGKSNHANKEGGDSC 180

Query: 1939 LSQKRRIPIPEDSDDEIPLSSKFQVKSNAGESINRSSNSGERKPLLSKYDQNGSASTE-- 1766
              ++  I   EDS+DE PLS +F  KS+ GES ++S +S E+KPL +K   NGSAS +  
Sbjct: 181  SIRRPVIEESEDSEDEKPLSRRFTSKSSLGESTSKSYDSDEKKPLAAKVQPNGSASRDSP 240

Query: 1765 -RKPSTNLKKRPGDGVKTTDESYLKKPKLSEAATPHKNKEASIKAEMREEDDE------- 1610
              K ++   KRP   VK+ ++S LKKPKLS   T   NK+A++K E + EDD+       
Sbjct: 241  MNKSASLSNKRPPGEVKSLNQSSLKKPKLSSPITSISNKQAAVKPEPKAEDDDDNIPLSQ 300

Query: 1609 -----------------DHVPISHRMXXXXXXXXXXXXXKN-ITKPIXXXXXXXXXXXXX 1484
                             D+VPIS R+                 +  +             
Sbjct: 301  RGKKSQTATSKPKDEDDDNVPISQRIKKSPASVSKSSAPVKKASTVVSPSLKKVNKKSKK 360

Query: 1483 XXXXXXXXXXXXXXXXSGEGQKWTTLVHNGVIFPPPYKPHGVKMLYKGKPVDLTPEQEEV 1304
                            SGEGQKWTTLVHNGVIFPPPYKPHGVKMLYK +P+ LTPEQEEV
Sbjct: 361  VIKKTAYTKSSKVPPGSGEGQKWTTLVHNGVIFPPPYKPHGVKMLYKRQPITLTPEQEEV 420

Query: 1303 ATMYAVMLETDYMNKPKFKENFMADWRKILGKNHTIQSLEHCDFTPIYEWHXXXXXXXXX 1124
            ATM+AVML+TDYMNKP+FKENF +DW+K+LGKNHTIQ+LE CDF PIYEWH         
Sbjct: 421  ATMFAVMLDTDYMNKPRFKENFFSDWKKMLGKNHTIQNLEDCDFGPIYEWHQQEKEKKKQ 480

Query: 1123 XXXXXXXXXXXXXXXXXXKYMWAIVNGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIR 944
                              KYMWAIV+GVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIR
Sbjct: 481  MTTEEKKALKEEKLQQEEKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIR 540

Query: 943  PSDITINIGKDAPIPECPIPGESWKEIRHDNTVTWLAYWNDPINPKEFKYVFLAASSTLK 764
            P DITINIGKDAPIPECPIPGE WKE+R+DNTVTWLAYWNDPIN KEFKYVFLAASSTLK
Sbjct: 541  PRDITINIGKDAPIPECPIPGERWKEVRNDNTVTWLAYWNDPINQKEFKYVFLAASSTLK 600

Query: 763  GQSDKEKYEKARLLKDYILGIRAAYTKDFTS-KDPAKRQIAVATYLIDKLALRAGNEKDD 587
            GQSDKEKYEKARLLKDYI GIRAAYTKDFT+ KDP K+QIAVATYLIDKLALRAGNEKDD
Sbjct: 601  GQSDKEKYEKARLLKDYIHGIRAAYTKDFTNNKDPMKKQIAVATYLIDKLALRAGNEKDD 660

Query: 586  DEADTVGCCTLKVENVEPVPPNTLKFDFLGKDSIRYQNEVEVETAVFKAIQQFRSGKKGG 407
            DEADTVGCCTLKVENVEPVPPN LKFDFLGKDSIRYQNEV+VE AVFKAIQQFRSGK+G 
Sbjct: 661  DEADTVGCCTLKVENVEPVPPNILKFDFLGKDSIRYQNEVQVEPAVFKAIQQFRSGKEGS 720

Query: 406  DDLFDRLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSRETRGGDVAEKVVVYQHA 227
            +DLFDRLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLS++T GG+VAEKVVVYQHA
Sbjct: 721  EDLFDRLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSKKTNGGEVAEKVVVYQHA 780

Query: 226  NKEVAIICNHQRTVSKSHSAQMLRLNEKIEELKGVVEELQTDLARAKKGKPPLKSADGKP 47
            NKEVAIICNHQRTVSKSHSAQM RLNEKI+ELK  +EEL+TDL+RAKKGKP  K ADGKP
Sbjct: 781  NKEVAIICNHQRTVSKSHSAQMSRLNEKIDELKTALEELKTDLSRAKKGKPLSKGADGKP 840

Query: 46   KRNLNPDALERKIAQ 2
            KRNLNP+ALERKIAQ
Sbjct: 841  KRNLNPEALERKIAQ 855


>dbj|BAG31375.1| topoisomerase I [Ophiorrhiza japonica]
          Length = 927

 Score =  983 bits (2542), Expect = 0.0
 Identities = 527/857 (61%), Positives = 602/857 (70%), Gaps = 35/857 (4%)
 Frame = -2

Query: 2467 MAVEACDKQKLXXXXXXXXEPLVFKRXXXXXXXXXXXSEAKKSLSQKHDRQLGRPAPDVR 2288
            MAVEAC    L         P++FKR           SE KK   QKH  Q      DVR
Sbjct: 1    MAVEACTPN-LMEDMEDDEGPVIFKRSNPASKQNQANSEKKKLSLQKHVGQSAVHTSDVR 59

Query: 2287 SQNGQSTIVKKSKTVPLSKTPPVKYPLTSPKSSNTSGKALALKSPEVDSKPSTSVTDKSN 2108
              NG+S+  +K +  P +KTPPVK PL+SPK+SN+S KA  + SP  +SKPS S T  + 
Sbjct: 60   PANGESSSAQKGRIQPSAKTPPVKSPLSSPKASNSSAKASPITSPGANSKPSASATSTAK 119

Query: 2107 SVKHQIKD----EKLSTEATGEPNEDSQDSEDDKPLSARLPAGLSKVNSNHAKKSPNTST 1940
               H        E   +    + N +S+ S+D+KPLSAR     SK  SNHA K    S 
Sbjct: 120  QQNHHKSSAAFIEPKPSVPAAKANSNSESSDDEKPLSARTFGCSSKGKSNHANKEGGDSC 179

Query: 1939 LSQKRRIPIPEDSDDEIPLSSKFQVKSNAGESINRSSNSGERKPLLSKYDQNGSASTE-- 1766
              ++R I   EDS+DE PLS +F  KS+ GES ++S +S E+KPL +K  QNGS S +  
Sbjct: 180  SIRRRVIEESEDSEDEKPLSRRFTSKSSLGESTSKSYDSDEKKPLAAKVQQNGSVSRDGP 239

Query: 1765 -RKPSTNLKKRPGDGVKTTDESYLKKPKLSEAATPHKNKEASIKAEMR------------ 1625
              K ++   KRP   VK+ ++S +KKPKLS   T   NK+A++K E              
Sbjct: 240  MNKSASLSNKRPPGEVKSLNQSSVKKPKLSSPITSISNKQAAVKPEPEPKAEDDDDNIPL 299

Query: 1624 --------------EEDDEDHVPISHRMXXXXXXXXXXXXXKN-ITKPIXXXXXXXXXXX 1490
                          +++D+D+VPI+ R+                 +  +           
Sbjct: 300  SQRGKKSQAATSKPKDEDDDNVPIAQRIKKSPASVSKSSAPVKKASTVVSPSLKKVNKNS 359

Query: 1489 XXXXXXXXXXXXXXXXXXSGEGQKWTTLVHNGVIFPPPYKPHGVKMLYKGKPVDLTPEQE 1310
                              SGEGQKWTTLVHNGVIFPPPY PHGVKMLYK +P+ LTPEQE
Sbjct: 360  KKVIKKTAYTKSSKVPPGSGEGQKWTTLVHNGVIFPPPYNPHGVKMLYKRQPITLTPEQE 419

Query: 1309 EVATMYAVMLETDYMNKPKFKENFMADWRKILGKNHTIQSLEHCDFTPIYEWHXXXXXXX 1130
            EVATM+AVML+TDYMNKP+FKENF +DW+K+LGKNHTIQ+LE CDF PIYEWH       
Sbjct: 420  EVATMFAVMLDTDYMNKPRFKENFFSDWKKMLGKNHTIQNLEDCDFGPIYEWHQQEKEKK 479

Query: 1129 XXXXXXXXXXXXXXXXXXXXKYMWAIVNGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKR 950
                                KYMWAIV+GVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKR
Sbjct: 480  KQMTTEEKKALKEDKLQQEEKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKR 539

Query: 949  IRPSDITINIGKDAPIPECPIPGESWKEIRHDNTVTWLAYWNDPINPKEFKYVFLAASST 770
            IRP DITINIGKDAPIPECPIPGE WKE+R+DNTVTWLA+W DPIN KEFKYVFLAASST
Sbjct: 540  IRPRDITINIGKDAPIPECPIPGERWKEVRNDNTVTWLAFWIDPINQKEFKYVFLAASST 599

Query: 769  LKGQSDKEKYEKARLLKDYILGIRAAYTKDFTS-KDPAKRQIAVATYLIDKLALRAGNEK 593
            LKGQSDKEKYEKARLLKDYI GIRAAYTKDFT+ KDP K+QIAVATYLIDKLALRAGNEK
Sbjct: 600  LKGQSDKEKYEKARLLKDYIHGIRAAYTKDFTNNKDPMKKQIAVATYLIDKLALRAGNEK 659

Query: 592  DDDEADTVGCCTLKVENVEPVPPNTLKFDFLGKDSIRYQNEVEVETAVFKAIQQFRSGKK 413
            DDDEADTVGCCTLKVENVEPVPPN LKFDFLGKDSIRYQNEV+VE AVFKAIQQFRSGK+
Sbjct: 660  DDDEADTVGCCTLKVENVEPVPPNILKFDFLGKDSIRYQNEVQVEPAVFKAIQQFRSGKE 719

Query: 412  GGDDLFDRLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSRETRGGDVAEKVVVYQ 233
            G +DLFDRLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLS+ET+GG+VAEKVVVYQ
Sbjct: 720  GSEDLFDRLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSKETKGGEVAEKVVVYQ 779

Query: 232  HANKEVAIICNHQRTVSKSHSAQMLRLNEKIEELKGVVEELQTDLARAKKGKPPLKSADG 53
            HANKEVAIICNHQRTVSKSHSAQM RLNEKI+ELK  +EEL+TDL+R KKGKPP K ADG
Sbjct: 780  HANKEVAIICNHQRTVSKSHSAQMSRLNEKIDELKTAMEELKTDLSRVKKGKPPSKGADG 839

Query: 52   KPKRNLNPDALERKIAQ 2
            KPKRNLNP+ALERK+AQ
Sbjct: 840  KPKRNLNPEALERKMAQ 856


>dbj|BAK32960.1| topoisomerase I [Ophiorrhiza pseudofasciculata]
          Length = 925

 Score =  983 bits (2542), Expect = 0.0
 Identities = 530/855 (61%), Positives = 598/855 (69%), Gaps = 33/855 (3%)
 Frame = -2

Query: 2467 MAVEACDKQKLXXXXXXXXEPLVFKRXXXXXXXXXXXSEAKKSLSQKHDRQLGRPAPDVR 2288
            MAVEAC    L         P++FKR           SE KK   QK D Q      DVR
Sbjct: 1    MAVEACTTN-LMEDMEDDGGPVIFKRSKPAPKQNQANSEKKKLSLQKQDGQSAVHTSDVR 59

Query: 2287 SQNGQSTIVKKSKTVPLSKTPPVKYPLTSPKSSNTSGKALALKSPEVDSKPSTSVTDKSN 2108
              NG+S+  +K +  P +KTPPVK PL+SPK+SN+S KA  + SP  +SKPS S T  + 
Sbjct: 60   PANGESSSAQKGRIQPSAKTPPVKSPLSSPKASNSSAKASPITSPGANSKPSASATSTAK 119

Query: 2107 SVKHQIKD----EKLSTEATGEPNEDSQDSEDDKPLSARLPAGLSKVNSNHAKKSPNTST 1940
               H        E   +    + N +S+ S+D+KPLSAR     SK  SNHA K    S 
Sbjct: 120  QQNHHKSSAAFIEPKPSVPAAKANSNSESSDDEKPLSARTFGCSSKGKSNHANKEGGDSC 179

Query: 1939 LSQKRRIPIPEDSDDEIPLSSKFQVKSNAGESINRSSNSGERKPLLSKYDQNGSASTE-- 1766
              ++  I   EDS+DE PLS +F  KS+ GES ++S +S E+KPL +K  QNGSAS +  
Sbjct: 180  SIRRPVIEESEDSEDEKPLSCRFTSKSSLGESTSKSYDSDEKKPLAAKVQQNGSASRDGP 239

Query: 1765 -RKPSTNLKKRPGDGVKTTDESYLKKPKLSEAATPHKNKEASIKAEMREEDDE------- 1610
              K ++   KRP    K+ ++S +KKPKLS   T   NK+A++K E + EDD+       
Sbjct: 240  MNKSASLSNKRPPGEAKSLNQSSVKKPKLSSPITSISNKQAAVKPEPKAEDDDDNIPLSQ 299

Query: 1609 -----------------DHVPISHRMXXXXXXXXXXXXXKN-ITKPIXXXXXXXXXXXXX 1484
                             D+VPIS R+                 +  +             
Sbjct: 300  RGKKSQSATSKPKDDDDDNVPISQRIKKSPASVSKSSVPVKKASTVVSSSLKKVNKNSKK 359

Query: 1483 XXXXXXXXXXXXXXXXSGEGQKWTTLVHNGVIFPPPYKPHGVKMLYKGKPVDLTPEQEEV 1304
                            SGEGQKWTTLVHNGVIFPPPYKPHGVKMLYK +P+ LTPEQEEV
Sbjct: 360  VIKKTAYTKSSKVPPGSGEGQKWTTLVHNGVIFPPPYKPHGVKMLYKRQPITLTPEQEEV 419

Query: 1303 ATMYAVMLETDYMNKPKFKENFMADWRKILGKNHTIQSLEHCDFTPIYEWHXXXXXXXXX 1124
            ATM+AVML+TDYMNKP FKENF +DW+KILGKNH IQ+LE CDF PIYEWH         
Sbjct: 420  ATMFAVMLDTDYMNKPCFKENFFSDWKKILGKNHMIQNLEDCDFGPIYEWHQQEKEKKKQ 479

Query: 1123 XXXXXXXXXXXXXXXXXXKYMWAIVNGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIR 944
                              KYMWAIV+GVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIR
Sbjct: 480  MTTEEKKALKEEKLQQEEKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIR 539

Query: 943  PSDITINIGKDAPIPECPIPGESWKEIRHDNTVTWLAYWNDPINPKEFKYVFLAASSTLK 764
            P DITINIGKDAPIPECPIPGE WKE+R+ NTVTWLAYWNDPIN KEFKYVFLAASSTLK
Sbjct: 540  PRDITINIGKDAPIPECPIPGERWKEVRNGNTVTWLAYWNDPINQKEFKYVFLAASSTLK 599

Query: 763  GQSDKEKYEKARLLKDYILGIRAAYTKDFTS-KDPAKRQIAVATYLIDKLALRAGNEKDD 587
            GQSDKEKYEKARLLKDYI GIRAAYTKDFT+ KDP K+QIAVATYLIDKLALRAGNEKDD
Sbjct: 600  GQSDKEKYEKARLLKDYIHGIRAAYTKDFTNNKDPMKKQIAVATYLIDKLALRAGNEKDD 659

Query: 586  DEADTVGCCTLKVENVEPVPPNTLKFDFLGKDSIRYQNEVEVETAVFKAIQQFRSGKKGG 407
            DEADTVGCCTLKVENVEPVPPN LKFDFLGKDSIRYQNEV+VE AVFKAIQQFRSGK+G 
Sbjct: 660  DEADTVGCCTLKVENVEPVPPNILKFDFLGKDSIRYQNEVQVEPAVFKAIQQFRSGKEGS 719

Query: 406  DDLFDRLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSRETRGGDVAEKVVVYQHA 227
            +DLFDRLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLS+ET+GG+VAE VVVYQHA
Sbjct: 720  EDLFDRLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSKETKGGEVAENVVVYQHA 779

Query: 226  NKEVAIICNHQRTVSKSHSAQMLRLNEKIEELKGVVEELQTDLARAKKGKPPLKSADGKP 47
            NKEVAIICNHQRTVSKSHSAQM RLNEKI+ELK  +EEL+TDL+RAKKGKPP K ADGK 
Sbjct: 780  NKEVAIICNHQRTVSKSHSAQMSRLNEKIDELKTALEELKTDLSRAKKGKPPTKGADGKA 839

Query: 46   KRNLNPDALERKIAQ 2
            KRNLNP+ALERKI Q
Sbjct: 840  KRNLNPEALERKITQ 854


>ref|XP_010266803.1| PREDICTED: DNA topoisomerase 1 alpha-like [Nelumbo nucifera]
          Length = 890

 Score =  932 bits (2408), Expect = 0.0
 Identities = 507/839 (60%), Positives = 582/839 (69%), Gaps = 16/839 (1%)
 Frame = -2

Query: 2470 LMAVEACDKQKLXXXXXXXXEPLVFKRXXXXXXXXXXXSEAKKSLSQKHDRQLGRPAPDV 2291
            +MAV+AC K K          P++FKR            E KK  S+K D   G+   D 
Sbjct: 1    MMAVDACIKPKFFDDGDDDEGPIIFKRNNASSKKNQLNKELKKVSSRKRDGSSGKCVSDS 60

Query: 2290 RSQNGQSTIVKKSKTVPLSKTPPVKYPLTSPKSSNTSGKALALKSPEVDSKPSTSVTDK- 2114
             S NGQ++ ++K K V                    S KA   KS E  SK STS+TDK 
Sbjct: 61   FSPNGQNSSLQKGKAVQ-------------------SSKASTGKSTETSSKASTSITDKL 101

Query: 2113 -SNSVKHQIKD--EKLSTEATGEPNEDSQDSEDDKPLSARLP--AGLSKVNSNHAKKSPN 1949
              +  K+   D  EK   +   EP  DS DS+DDKPLS RLP  A L K  S+   K  +
Sbjct: 102  KCSPQKNSSIDNMEKQLKKPCNEPYTDSVDSDDDKPLSIRLPTSASLLKCKSSPVSKGLS 161

Query: 1948 T----STLSQKRRIP---IPEDSDDEIPLSSKFQVKSNAGESINRSSNSGERKPLLSKYD 1790
            +    S+ S+K  +      EDS+DE+PLS K ++K + G S  +  +SGE KPL+SK  
Sbjct: 162  SPVASSSQSEKTNVTNKKSSEDSEDELPLSLKLKLKPSVGLSGKKFYDSGEEKPLVSKLQ 221

Query: 1789 QNGSASTERKP---STNLKKRPGDGVKTTDESYLKKPKLSEAATPHKNKEASIKAEMREE 1619
            QNGS+  + +P     NL KRP  G  ++ +S +KK K+SE + P K K+ SIK+E +EE
Sbjct: 222  QNGSSKRDNEPLKSPKNLNKRPLSGANSSGQSLVKKLKVSEVSVPTKVKQTSIKSEPKEE 281

Query: 1618 DDEDHVPISHRMXXXXXXXXXXXXXKNITKPIXXXXXXXXXXXXXXXXXXXXXXXXXXXX 1439
            D++D +PIS R+             K  TK +                            
Sbjct: 282  DEDD-IPISQRLKKSASSDDKSLSLKKTTKVVSSSFKKTTNKLKKAAKNSKYSKSTKMPP 340

Query: 1438 XSGEGQKWTTLVHNGVIFPPPYKPHGVKMLYKGKPVDLTPEQEEVATMYAVMLETDYMNK 1259
             SGEGQKWTTL HNGVIFPP YKPHGVKMLY GKPVDLTPEQEEVATM+AVM +TDY  K
Sbjct: 341  SSGEGQKWTTLEHNGVIFPPLYKPHGVKMLYNGKPVDLTPEQEEVATMFAVMKDTDYATK 400

Query: 1258 PKFKENFMADWRKILGKNHTIQSLEHCDFTPIYEWHXXXXXXXXXXXXXXXXXXXXXXXX 1079
             +F ENFM DWR ILGKNH I+  E CDFTPIYEWH                        
Sbjct: 401  SRFIENFMNDWRTILGKNHVIKKFELCDFTPIYEWHQREKEKKKQMSAEEKKALKEEKLK 460

Query: 1078 XXXKYMWAIVNGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIRPSDITINIGKDAPIP 899
               KYMWAIV+GVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRI PSDITINIGK APIP
Sbjct: 461  QEEKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIHPSDITINIGKGAPIP 520

Query: 898  ECPIPGESWKEIRHDNTVTWLAYWNDPINPKEFKYVFLAASSTLKGQSDKEKYEKARLLK 719
            ECPIPGE WKE+RHDNTVTWLA+WNDPINPKEFKYVFLAASS+LKGQSDKEKYEKARLLK
Sbjct: 521  ECPIPGERWKEVRHDNTVTWLAFWNDPINPKEFKYVFLAASSSLKGQSDKEKYEKARLLK 580

Query: 718  DYILGIRAAYTKDFTSKDPAKRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENV 539
            DYI  IRA YT+DF SKD  KRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENV
Sbjct: 581  DYIKDIRANYTRDFVSKDITKRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENV 640

Query: 538  EPVPPNTLKFDFLGKDSIRYQNEVEVETAVFKAIQQFRSGKKGGDDLFDRLDTSKLNAHL 359
            E VPPN L+FDFLGKDSIRY N VEVE AV+KAI QF++GK+ G+DLFD LDTSKLNAHL
Sbjct: 641  ELVPPNKLQFDFLGKDSIRYFNTVEVELAVYKAIGQFKNGKEDGEDLFDSLDTSKLNAHL 700

Query: 358  KELMPGLTAKVFRTYNASITLDDMLSRETRGGDVAEKVVVYQHANKEVAIICNHQRTVSK 179
            KELMPGLTAKVFRTYNASITLD+ML+RE++GGDVAEK+ VYQHANKEVAIICNHQR+VSK
Sbjct: 701  KELMPGLTAKVFRTYNASITLDEMLNRESKGGDVAEKIAVYQHANKEVAIICNHQRSVSK 760

Query: 178  SHSAQMLRLNEKIEELKGVVEELQTDLARAKKGKPPLKSADGKPKRNLNPDALERKIAQ 2
            SHSAQM RL++KI+ELK  ++EL+TDLARAKKGKPPLK ADGKPKRNL P+ALE+KIAQ
Sbjct: 761  SHSAQMHRLDDKIKELKDALDELKTDLARAKKGKPPLKGADGKPKRNLTPEALEKKIAQ 819


>ref|XP_023553297.1| DNA topoisomerase 1 beta-like [Cucurbita pepo subsp. pepo]
          Length = 887

 Score =  927 bits (2395), Expect = 0.0
 Identities = 498/829 (60%), Positives = 582/829 (70%), Gaps = 7/829 (0%)
 Frame = -2

Query: 2467 MAVEACDKQKLXXXXXXXXEPLVFKRXXXXXXXXXXXSEAKKSLSQKHDRQLGRPAPDVR 2288
            MAVE   K  +         P+VFKR            E K S SQ+ ++  GRP  D  
Sbjct: 1    MAVETFGKAPMFDDDDEDNMPIVFKRSSASRQNQLNS-EVKHSQSQRLNQLSGRPGSDAC 59

Query: 2287 SQNGQSTIVKKSKTVPLSKTPPVKYPLTSPKSSNTSGKALALKSPEVDSKPST-SVTDKS 2111
            S NGQS+  +K  T  L KT P++  + S K+S +S     ++ P V S  +T  V+D  
Sbjct: 60   SANGQSSNAQKRMT-SLPKTSPMRPEIGSQKASKSS-----IQEPLVKSLGTTLKVSDSM 113

Query: 2110 NSVKHQIKDEKLSTEATG-EPNEDSQDSEDDKPLSARLPAGLSKVNSNHAKKSPNTSTLS 1934
            +S   Q+ +  +  E     P +D+ DSEDDKPLS RL     K NSNH  K P   T+ 
Sbjct: 114  DSRPKQLANAAVKEENDSIHPTQDNSDSEDDKPLSIRL-----KGNSNHPSKGP-IPTVQ 167

Query: 1933 QKRRIPIPEDSDDEIPLSSKFQVKSNAGESINRSSNSGERKPLLSKYDQNGSASTER--K 1760
            + +     EDSDDE+PLSSKFQ+KS +G    R     E+KPL SK  QNGS S ++  K
Sbjct: 168  KNKIKKSSEDSDDEVPLSSKFQMKSASGVLGGRQHGFDEKKPLDSKVHQNGSTSRDKLQK 227

Query: 1759 PSTNLKKRPGDGVKTTDESYL--KKPKLSEAATPHKNKEASIKAEMREEDDEDHVPISHR 1586
            P+    KRP     +   S +  KKPKLS+++TP      S+KA+    DD+DH+PIS R
Sbjct: 228  PAVVSSKRPLPNADSHSSSQISSKKPKLSDSSTPLSTNTVSLKAKQEVADDDDHIPISQR 287

Query: 1585 MXXXXXXXXXXXXXKNITKPIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSGEGQK-WTT 1409
            M             K ++K                               SG+GQK WTT
Sbjct: 288  MKMSAAVNKSSGSKKTVSKVASSSIKKTLKKSKKPVKKSKYVKSTKLLPSSGDGQKKWTT 347

Query: 1408 LVHNGVIFPPPYKPHGVKMLYKGKPVDLTPEQEEVATMYAVMLETDYMNKPKFKENFMAD 1229
            LVHNGVIFPPPY+ HGVK+L+KGKPVDLTPEQEEVATM+AVM +TDYM KPKFKENF  D
Sbjct: 348  LVHNGVIFPPPYQTHGVKILHKGKPVDLTPEQEEVATMFAVMKDTDYMQKPKFKENFWND 407

Query: 1228 WRKILGKNHTIQSLEHCDFTPIYEWHXXXXXXXXXXXXXXXXXXXXXXXXXXXKYMWAIV 1049
            WRK+LGKNH IQ+L+ CDFTPIY+W+                           KYMWAI+
Sbjct: 408  WRKLLGKNHVIQNLDDCDFTPIYDWYQTEKEKKKQMTTEEKKALKEEKLKQEEKYMWAIL 467

Query: 1048 NGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIRPSDITINIGKDAPIPECPIPGESWK 869
            +GVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIRPSDITINIGKDAPIPECPIPG+ WK
Sbjct: 468  DGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIRPSDITINIGKDAPIPECPIPGQRWK 527

Query: 868  EIRHDNTVTWLAYWNDPINPKEFKYVFLAASSTLKGQSDKEKYEKARLLKDYILGIRAAY 689
            E+RHDNTVTWLA+WNDPINPKEFKYVFLAASS+LKGQSDKEKYEKAR+LKDYI  IR +Y
Sbjct: 528  EVRHDNTVTWLAFWNDPINPKEFKYVFLAASSSLKGQSDKEKYEKARMLKDYIKNIRNSY 587

Query: 688  TKDFTSKDPAKRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVEPVPPNTLKF 509
            TKDFTSKDP +RQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENV+ VPPN L+F
Sbjct: 588  TKDFTSKDPTRRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVKAVPPNLLEF 647

Query: 508  DFLGKDSIRYQNEVEVETAVFKAIQQFRSGKKGGDDLFDRLDTSKLNAHLKELMPGLTAK 329
            +FLGKDSI+Y+N VEVE  VFKAI QF+SGK G DDLFD+LDTSKLNAHLK+LMPGLTAK
Sbjct: 648  NFLGKDSIKYENTVEVELPVFKAITQFQSGKSGSDDLFDKLDTSKLNAHLKDLMPGLTAK 707

Query: 328  VFRTYNASITLDDMLSRETRGGDVAEKVVVYQHANKEVAIICNHQRTVSKSHSAQMLRLN 149
            VFRTYNASITLDDML+R T+ G+V+EK+V YQHANKEVAIICNHQRTVSKSH AQM RLN
Sbjct: 708  VFRTYNASITLDDMLNRGTKDGEVSEKIVTYQHANKEVAIICNHQRTVSKSHGAQMTRLN 767

Query: 148  EKIEELKGVVEELQTDLARAKKGKPPLKSADGKPKRNLNPDALERKIAQ 2
            EKI EL+ +V+EL+ DL RAKKGKPPLK +DGK KRNL P+ALE+KI+Q
Sbjct: 768  EKISELRDIVKELKIDLDRAKKGKPPLKGSDGKQKRNLTPEALEKKISQ 816


>gb|KVI01089.1| DNA breaking-rejoining enzyme, catalytic core [Cynara cardunculus
            var. scolymus]
          Length = 778

 Score =  926 bits (2392), Expect = 0.0
 Identities = 485/721 (67%), Positives = 542/721 (75%), Gaps = 2/721 (0%)
 Frame = -2

Query: 2158 SPEVDSKPSTSVTDKSNSVKHQIKDEKLSTEATGEPNEDSQDSEDDKPLSARLPAGLSKV 1979
            S + D KP   +  + +S   ++K    S   + +P+ D  DSEDDKPLS RL   +SK 
Sbjct: 4    SSDEDDKP---LVFRRSSKADKVKCSSQSLRPSPKPSNDLTDSEDDKPLSFRLST-VSKG 59

Query: 1978 NSNHAKKSPNTSTLSQKRRIPIPEDSDDEIPLSSKFQVKSNAGESINRSSNSGERKPLLS 1799
            N+NHAKK    +     +     EDSDDE PLSSK+  K N   SI++ S S   K L S
Sbjct: 60   NTNHAKKGSCMNVSPLPKPQVKDEDSDDEKPLSSKYISKPNVVSSISKHSGSNNDKTLTS 119

Query: 1798 KYDQNGSASTERKP-STNLKKRPGDGVKTTDESYLKKPKLSEAATPHKNKEASIKAEMRE 1622
            K  QNGSAS + +  ST   KRP D  +++ +S  KKPKLSE++TP   K+  +KAE   
Sbjct: 120  KVHQNGSASRDNQSRSTGSIKRPLDEERSSSQSLAKKPKLSESSTPINRKQVPLKAETES 179

Query: 1621 EDDE-DHVPISHRMXXXXXXXXXXXXXKNITKPIXXXXXXXXXXXXXXXXXXXXXXXXXX 1445
            +DDE D VPIS R+             K+                               
Sbjct: 180  DDDEEDDVPISQRIKNHAPSGSKSSSVKHKVTKKNSSLKETNKKSKKVVKNSKYSKPSKV 239

Query: 1444 XXXSGEGQKWTTLVHNGVIFPPPYKPHGVKMLYKGKPVDLTPEQEEVATMYAVMLETDYM 1265
               SGEGQKWT+LVH+GVIFPP YKPHGVK+LYKGKPVDLTPEQEEVATM+AVML+TDYM
Sbjct: 240  PPGSGEGQKWTSLVHSGVIFPPAYKPHGVKILYKGKPVDLTPEQEEVATMFAVMLDTDYM 299

Query: 1264 NKPKFKENFMADWRKILGKNHTIQSLEHCDFTPIYEWHXXXXXXXXXXXXXXXXXXXXXX 1085
             KPKFKENF  DWRKILG+NHTIQ+L+ CDF PIYEWH                      
Sbjct: 300  TKPKFKENFWDDWRKILGRNHTIQNLDDCDFKPIYEWHQTEKEKKKQMSTEEKKALKEEK 359

Query: 1084 XXXXXKYMWAIVNGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIRPSDITINIGKDAP 905
                 KYMWAIV+GVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRI PSDITINIGKDAP
Sbjct: 360  MKLEEKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIHPSDITINIGKDAP 419

Query: 904  IPECPIPGESWKEIRHDNTVTWLAYWNDPINPKEFKYVFLAASSTLKGQSDKEKYEKARL 725
            IPECPIPGESWKEIRHDNTVTWLAYWNDPIN KEFKYVFLAASS+LKGQSDKEKYEKAR+
Sbjct: 420  IPECPIPGESWKEIRHDNTVTWLAYWNDPINSKEFKYVFLAASSSLKGQSDKEKYEKARM 479

Query: 724  LKDYILGIRAAYTKDFTSKDPAKRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVE 545
            LK YI GIR AYT+DF +KD  KRQ+AVATYLIDKLALRAGNEKDDDEADTVGCCTLKVE
Sbjct: 480  LKGYIQGIRNAYTRDFGNKDLTKRQVAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVE 539

Query: 544  NVEPVPPNTLKFDFLGKDSIRYQNEVEVETAVFKAIQQFRSGKKGGDDLFDRLDTSKLNA 365
            NVEP PPN LKFDFLGKDSIRYQNEVEVE  VFKAIQQFR+GK+G DDLFD+LDTSKLNA
Sbjct: 540  NVEPKPPNILKFDFLGKDSIRYQNEVEVELPVFKAIQQFRTGKQGTDDLFDKLDTSKLNA 599

Query: 364  HLKELMPGLTAKVFRTYNASITLDDMLSRETRGGDVAEKVVVYQHANKEVAIICNHQRTV 185
            HLKELMPGLTAKVFRTYNASITLDDMLSRET+GGDVA+ +VVYQHANKEVAIICNHQRTV
Sbjct: 600  HLKELMPGLTAKVFRTYNASITLDDMLSRETKGGDVAQNLVVYQHANKEVAIICNHQRTV 659

Query: 184  SKSHSAQMLRLNEKIEELKGVVEELQTDLARAKKGKPPLKSADGKPKRNLNPDALERKIA 5
            SKSHSAQM RLNEKI+ELKGV++EL+TDL RAKKGKPPLK++DGKPKRNLNP+AL +KIA
Sbjct: 660  SKSHSAQMTRLNEKIDELKGVIKELETDLVRAKKGKPPLKNSDGKPKRNLNPEALAKKIA 719

Query: 4    Q 2
            Q
Sbjct: 720  Q 720


>ref|XP_023007686.1| DNA topoisomerase 1 beta-like [Cucurbita maxima]
 ref|XP_023007687.1| DNA topoisomerase 1 beta-like [Cucurbita maxima]
 ref|XP_023007688.1| DNA topoisomerase 1 beta-like [Cucurbita maxima]
 ref|XP_023007689.1| DNA topoisomerase 1 beta-like [Cucurbita maxima]
          Length = 887

 Score =  920 bits (2379), Expect = 0.0
 Identities = 494/828 (59%), Positives = 581/828 (70%), Gaps = 6/828 (0%)
 Frame = -2

Query: 2467 MAVEACDKQKLXXXXXXXXEPLVFKRXXXXXXXXXXXSEAKKSLSQKHDRQLGRPAPDVR 2288
            MAVE   K  +         P+VFKR            E K S SQ+ ++  GRP  D  
Sbjct: 1    MAVETFGKATMFDDDDEDNMPIVFKRSSASRQNQLNS-EVKHSQSQRLNQLSGRPGSDAC 59

Query: 2287 SQNGQSTIVKKSKTVPLSKTPPVKYPLTSPKSSNTSGKALALKSPEVDSKPSTSVTDKSN 2108
            S NGQS+  +K  T  L KT P++  + S K+S +S +   +KS     K S S+  +  
Sbjct: 60   STNGQSSNAQKRMT-SLPKTSPMRPEIGSQKASKSSIQEPLVKSLGTTLKVSDSMDSRPK 118

Query: 2107 S-VKHQIKDEKLSTEATGEPNEDSQDSEDDKPLSARLPAGLSKVNSNHAKKSPNTSTLSQ 1931
              V   +K+E  S      P +++ DSEDDKPLS RL     K NSNH  K P   T+ +
Sbjct: 119  QLVNAAVKEENDSIH----PAQENSDSEDDKPLSIRL-----KGNSNHPSKGP-IPTVQK 168

Query: 1930 KRRIPIPEDSDDEIPLSSKFQVKSNAGESINRSSNSGERKPLLSKYDQNGSASTER--KP 1757
             +     EDSDDE+PLSSKF++KS +G    +     E+KPL SK  QNGS S+++  KP
Sbjct: 169  NKIKKSSEDSDDEVPLSSKFRMKSASGVLGGKQHGFDEKKPLDSKVHQNGSTSSDKLQKP 228

Query: 1756 STNLKKRPGDGVKTTDESYL--KKPKLSEAATPHKNKEASIKAEMREEDDEDHVPISHRM 1583
            +    KRP     +   S +  KKPKLS+++TP      S+KA+    DD+DH+PIS RM
Sbjct: 229  AVVSSKRPLPNADSHSSSQISSKKPKLSDSSTPLSTHTVSLKAKQEVVDDDDHIPISQRM 288

Query: 1582 XXXXXXXXXXXXXKNITKPIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSGEGQK-WTTL 1406
                         K ++K                               SG+GQK WTTL
Sbjct: 289  KMSAAVNKSSGSKKTVSKVASSSIKKTLKKSKKPVKKSKYVKSTKLLPSSGDGQKKWTTL 348

Query: 1405 VHNGVIFPPPYKPHGVKMLYKGKPVDLTPEQEEVATMYAVMLETDYMNKPKFKENFMADW 1226
            VHNGVIFPPPY+ HGVK+L+KGKPVDLTPEQEEVATM+AVM +TDYM KPKFKENF  DW
Sbjct: 349  VHNGVIFPPPYQTHGVKILHKGKPVDLTPEQEEVATMFAVMKDTDYMQKPKFKENFWNDW 408

Query: 1225 RKILGKNHTIQSLEHCDFTPIYEWHXXXXXXXXXXXXXXXXXXXXXXXXXXXKYMWAIVN 1046
            RK+LGKNH IQ+L+ CDFTPIY+W+                           KYMWAI++
Sbjct: 409  RKLLGKNHVIQNLDDCDFTPIYDWYQTEKEKKKQMTTEEKKALKEEKLKQEEKYMWAILD 468

Query: 1045 GVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIRPSDITINIGKDAPIPECPIPGESWKE 866
            GVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIRPSDITINIGKDAPIPECPIPG+ WKE
Sbjct: 469  GVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIRPSDITINIGKDAPIPECPIPGQRWKE 528

Query: 865  IRHDNTVTWLAYWNDPINPKEFKYVFLAASSTLKGQSDKEKYEKARLLKDYILGIRAAYT 686
            +RHDNTVTWLA+WNDPINPKEFKYVFLAASS+LKGQSDKEKYEKAR+LKDYI  IR +YT
Sbjct: 529  VRHDNTVTWLAFWNDPINPKEFKYVFLAASSSLKGQSDKEKYEKARMLKDYIKNIRNSYT 588

Query: 685  KDFTSKDPAKRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVEPVPPNTLKFD 506
            KDFTSKDP +RQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENV+ VPPN L+F+
Sbjct: 589  KDFTSKDPTRRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVKAVPPNLLEFN 648

Query: 505  FLGKDSIRYQNEVEVETAVFKAIQQFRSGKKGGDDLFDRLDTSKLNAHLKELMPGLTAKV 326
            FLGKDSI+Y+N VEVE  VFKAI QF+SGK G DDLFD+LDTSKLNAHLK+LMPGLTAKV
Sbjct: 649  FLGKDSIKYENTVEVELPVFKAITQFQSGKSGSDDLFDKLDTSKLNAHLKDLMPGLTAKV 708

Query: 325  FRTYNASITLDDMLSRETRGGDVAEKVVVYQHANKEVAIICNHQRTVSKSHSAQMLRLNE 146
            FRTYNASITLDDML+R T+ G+V+EK+V YQHANKEVAIICNHQRTVSKSH AQM RLNE
Sbjct: 709  FRTYNASITLDDMLNRGTKDGEVSEKIVTYQHANKEVAIICNHQRTVSKSHGAQMTRLNE 768

Query: 145  KIEELKGVVEELQTDLARAKKGKPPLKSADGKPKRNLNPDALERKIAQ 2
            KI EL+ +++EL+ DL RAKKGKPPLK +DGK KRNL P+ALE+KI+Q
Sbjct: 769  KISELRDILKELKIDLDRAKKGKPPLKGSDGKQKRNLTPEALEKKISQ 816


>ref|XP_022932254.1| DNA topoisomerase 1 beta-like [Cucurbita moschata]
 ref|XP_022932255.1| DNA topoisomerase 1 beta-like [Cucurbita moschata]
 ref|XP_022932256.1| DNA topoisomerase 1 beta-like [Cucurbita moschata]
 ref|XP_022932257.1| DNA topoisomerase 1 beta-like [Cucurbita moschata]
          Length = 887

 Score =  918 bits (2372), Expect = 0.0
 Identities = 493/829 (59%), Positives = 581/829 (70%), Gaps = 7/829 (0%)
 Frame = -2

Query: 2467 MAVEACDKQKLXXXXXXXXEPLVFKRXXXXXXXXXXXSEAKKSLSQKHDRQLGRPAPDVR 2288
            MAVE   K  +         P+VFKR            E K S SQ+ ++  GRP  D  
Sbjct: 1    MAVETFGKAPMFDDDDEDNMPIVFKRSSASRQNQLNS-EVKHSQSQRLNQLSGRPGSDAC 59

Query: 2287 SQNGQSTIVKKSKTVPLSKTPPVKYPLTSPKSSNTSGKALALKSPEVDSKPST-SVTDKS 2111
            S NGQS+  +K  T  L KT P++  + S K++ +S     ++ P V S  +T  V+D  
Sbjct: 60   SANGQSSNAQKRMT-SLPKTSPMRPEIGSQKAAKSS-----IQEPLVKSLGTTLKVSDSM 113

Query: 2110 NSVKHQIKDEKLSTEATG-EPNEDSQDSEDDKPLSARLPAGLSKVNSNHAKKSPNTSTLS 1934
            +S   Q+ +  +  E     P +++ DSEDDKPLS RL     K NSNH  K P   T+ 
Sbjct: 114  DSRPKQLANAAVKEENDSIHPTQENSDSEDDKPLSIRL-----KGNSNHPSKGP-IPTVQ 167

Query: 1933 QKRRIPIPEDSDDEIPLSSKFQVKSNAGESINRSSNSGERKPLLSKYDQNGSASTER--K 1760
            + +     EDSDDE+PLSSKFQ+KS +G    +     E+KPL SK  QNGS S ++  K
Sbjct: 168  KNKIKKSSEDSDDEVPLSSKFQMKSASGVLGGKQHGFHEKKPLDSKVHQNGSTSRDKLQK 227

Query: 1759 PSTNLKKRPGDGVKTTDESYL--KKPKLSEAATPHKNKEASIKAEMREEDDEDHVPISHR 1586
            P+    KRP     +   S +  KKPKLS+++TP      S+KA+    DD+DH+PIS R
Sbjct: 228  PAVVSSKRPLPNADSHSSSQISSKKPKLSDSSTPLSTNTVSLKAKQEVVDDDDHIPISQR 287

Query: 1585 MXXXXXXXXXXXXXKNITKPIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSGEGQK-WTT 1409
            M             K ++K                               SG+GQK WTT
Sbjct: 288  MKMSAAVNKSSGSKKTVSKVASSSIKKTLKKSKKPVKKSKYVKSTKLLPSSGDGQKKWTT 347

Query: 1408 LVHNGVIFPPPYKPHGVKMLYKGKPVDLTPEQEEVATMYAVMLETDYMNKPKFKENFMAD 1229
            LVHNGVIFPPPY+ HGVK+L+KGKPVDLT EQEEVATM+AVM +TDYM KPKFKENF  D
Sbjct: 348  LVHNGVIFPPPYQTHGVKILHKGKPVDLTTEQEEVATMFAVMKDTDYMQKPKFKENFWND 407

Query: 1228 WRKILGKNHTIQSLEHCDFTPIYEWHXXXXXXXXXXXXXXXXXXXXXXXXXXXKYMWAIV 1049
            WRK+LGKNH IQ+L+ CDFTPIY+W+                           KYMWAI+
Sbjct: 408  WRKLLGKNHVIQNLDDCDFTPIYDWYQTEKEKKKQMTTEEKKALKEEKLKQEEKYMWAIL 467

Query: 1048 NGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIRPSDITINIGKDAPIPECPIPGESWK 869
            +GVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIRPSDITINIGKDAPIPECPIPG+ WK
Sbjct: 468  DGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIRPSDITINIGKDAPIPECPIPGQRWK 527

Query: 868  EIRHDNTVTWLAYWNDPINPKEFKYVFLAASSTLKGQSDKEKYEKARLLKDYILGIRAAY 689
            E+RHDNTVTWLA+WNDPINPKEFKYVFLAASS+LKGQSDKEKYEKAR+LKDYI  IR +Y
Sbjct: 528  EVRHDNTVTWLAFWNDPINPKEFKYVFLAASSSLKGQSDKEKYEKARMLKDYIKNIRNSY 587

Query: 688  TKDFTSKDPAKRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVEPVPPNTLKF 509
            TKDFTSKDP +RQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENV+ VPPN L+F
Sbjct: 588  TKDFTSKDPTRRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVKAVPPNLLEF 647

Query: 508  DFLGKDSIRYQNEVEVETAVFKAIQQFRSGKKGGDDLFDRLDTSKLNAHLKELMPGLTAK 329
            +FLGKDSI+Y+N VEVE  VFKAI QF+SGK G DDLFD+LDTSKLNAHLK+LMPGLTAK
Sbjct: 648  NFLGKDSIKYENTVEVELPVFKAITQFQSGKSGSDDLFDKLDTSKLNAHLKDLMPGLTAK 707

Query: 328  VFRTYNASITLDDMLSRETRGGDVAEKVVVYQHANKEVAIICNHQRTVSKSHSAQMLRLN 149
            VFRTYNASITLDDML+R T+ G+V+EK+V YQHANKEVAIICNHQRTVSKSH AQM RLN
Sbjct: 708  VFRTYNASITLDDMLNRGTKDGEVSEKIVTYQHANKEVAIICNHQRTVSKSHGAQMTRLN 767

Query: 148  EKIEELKGVVEELQTDLARAKKGKPPLKSADGKPKRNLNPDALERKIAQ 2
            EKI EL+ +++EL+ DL RAKKGKPPLK +DGK KRNL P+ALE+KI+Q
Sbjct: 768  EKISELRDILKELKIDLDRAKKGKPPLKGSDGKQKRNLTPEALEKKISQ 816


>gb|PON81509.1| DNA topoisomerase I [Trema orientalis]
          Length = 897

 Score =  903 bits (2333), Expect = 0.0
 Identities = 491/830 (59%), Positives = 576/830 (69%), Gaps = 8/830 (0%)
 Frame = -2

Query: 2467 MAVEACDKQKLXXXXXXXXEPLVFKRXXXXXXXXXXXSEAKKSLSQKHDRQLGRPAPDVR 2288
            MAV+A  K  L         P+VFKR           SE KK LSQK D Q GR   D  
Sbjct: 1    MAVQAPAKPNLVDDYDEDE-PIVFKRTNPISKQNQLNSEVKKPLSQKPDGQSGRQISDRV 59

Query: 2287 SQNGQSTIVKKSKTVPLSKTPPVKYPLTSPKSSNTSGKALALKSPEVDSKPSTSVTDKSN 2108
            S N  ++  +K K V  ++   VK  + SPK+S +S K   LKSP  +SK STS+  +S 
Sbjct: 60   SLNDLNSSSQKGKVVQSNRALVVKSSVASPKASASSAKTSPLKSPITNSKTSTSLDGQSK 119

Query: 2107 SVKHQ-----IKDEKLSTEATGEPNEDSQDSEDDKPLSARLPAGLSKVNSNHAKKSPNTS 1943
                +     +K+EK S +     +  S+DSEDD PLSARL    S+  S    K    S
Sbjct: 120  FSLEKNKSSIVKEEKSSIKQPIRSDSHSEDSEDDIPLSARLKGSTSQ-GSKGLVKPTTAS 178

Query: 1942 TLSQKRRIPIPEDSDDEIPLSSKFQVKSNAGESINRSSNSGERKPLLSKYDQNGSASTE- 1766
             L    +  + ED  D  PLSS+FQ+K N G S ++ ++  ++KPLLS   QNGS  T+ 
Sbjct: 179  KLPPVTKSVVKEDDSDNEPLSSRFQMKPNVGTSGSKPNDFNDKKPLLSINKQNGSTVTDV 238

Query: 1765 RKPSTNLKKRPGDGVKTTDESYLKKPKLSEAATPHKNKEASIKAEMREEDDEDHVPISHR 1586
            +KP     KRP D  K+ D+S +K+PKLS++    KNK+ S+KAE + +DD DHVPIS R
Sbjct: 239  KKPLNTNTKRPLDREKS-DQSSVKRPKLSDSPALLKNKQVSVKAESKVDDD-DHVPISQR 296

Query: 1585 MXXXXXXXXXXXXXKN-ITKPIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSGEGQK-WT 1412
            +             K  +TKP+                             SG+GQK WT
Sbjct: 297  IKKSPASNNKSSTTKQKVTKPVSSSFKKTTKKFKKGAKNSKYSKSTKLSPSSGDGQKKWT 356

Query: 1411 TLVHNGVIFPPPYKPHGVKMLYKGKPVDLTPEQEEVATMYAVMLETDYMNKPKFKENFMA 1232
            TL+HNGVIFPPPY+PHGVK+ Y GKPVDLTP QEEVATM+AVM +TDY  K  F+ENF  
Sbjct: 357  TLIHNGVIFPPPYQPHGVKLFYNGKPVDLTPVQEEVATMFAVMKDTDYAEKKTFRENFWN 416

Query: 1231 DWRKILGKNHTIQSLEHCDFTPIYEWHXXXXXXXXXXXXXXXXXXXXXXXXXXXKYMWAI 1052
            DWRK+LGKNH IQ L+ CDFTPIY+W+                           KYMWAI
Sbjct: 417  DWRKLLGKNHVIQKLDLCDFTPIYDWYQNEKEKKKQMSADEKKALKEEKLKQEEKYMWAI 476

Query: 1051 VNGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIRPSDITINIGKDAPIPECPIPGESW 872
            V+GVKEKVGNFRVEPPGLFRGRGEHPK GKLK+RIRPSD+TINIGKDAP+PECPIPGE W
Sbjct: 477  VDGVKEKVGNFRVEPPGLFRGRGEHPKSGKLKRRIRPSDVTINIGKDAPVPECPIPGERW 536

Query: 871  KEIRHDNTVTWLAYWNDPINPKEFKYVFLAASSTLKGQSDKEKYEKARLLKDYILGIRAA 692
            KE+RHDNTVTWLA+WNDPINPKEFKYVFLAASS+LKGQSDKEKYEKAR+LKDYI  IRAA
Sbjct: 537  KEVRHDNTVTWLAFWNDPINPKEFKYVFLAASSSLKGQSDKEKYEKARMLKDYIHNIRAA 596

Query: 691  YTKDFTSKDPAKRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVEPVPPNTLK 512
            YTKDFTSKD  KRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENV+ + PN L+
Sbjct: 597  YTKDFTSKDVTKRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVKAIAPNKLE 656

Query: 511  FDFLGKDSIRYQNEVEVETAVFKAIQQFRSGKKGGDDLFDRLDTSKLNAHLKELMPGLTA 332
            F+FLGKDSIRY+N VEVE  V+KAI QF+SGKKG DDLFD LDTSKLNAHLKELMPGLTA
Sbjct: 657  FNFLGKDSIRYENTVEVELPVYKAIIQFQSGKKGNDDLFDLLDTSKLNAHLKELMPGLTA 716

Query: 331  KVFRTYNASITLDDMLSRETRGGDVAEKVVVYQHANKEVAIICNHQRTVSKSHSAQMLRL 152
            KVFRTYNASITLDDML++ET+ GD+ EK  VY  ANK+VAIICNHQRT+SKSH AQM +L
Sbjct: 717  KVFRTYNASITLDDMLNQETKDGDLEEKKTVYNTANKQVAIICNHQRTISKSHEAQMSKL 776

Query: 151  NEKIEELKGVVEELQTDLARAKKGKPPLKSADGKPKRNLNPDALERKIAQ 2
             EKI EL+ VV+EL+ DL RA+KGKPPLK ADGK KRNL+P+AL +KI Q
Sbjct: 777  MEKIRELEDVVKELEVDLERARKGKPPLKDADGKTKRNLSPEALGKKINQ 826


>ref|XP_017215919.1| PREDICTED: DNA topoisomerase 1-like [Daucus carota subsp. sativus]
 ref|XP_017215920.1| PREDICTED: DNA topoisomerase 1-like [Daucus carota subsp. sativus]
          Length = 789

 Score =  877 bits (2265), Expect = 0.0
 Identities = 472/722 (65%), Positives = 529/722 (73%), Gaps = 7/722 (0%)
 Frame = -2

Query: 2146 DSKPSTSVTDK--SNSVKHQIKDEKLSTEATGEPNEDSQDSEDDKPLSARLPAGLSKVNS 1973
            +S P  ++  +  SN ++  +K+E       G+   +S+DS+DDKPLS +L +G    NS
Sbjct: 25   ESNPEITIIKQNASNVMEKTLKEE-------GQSRSNSEDSDDDKPLSVKLSSGALNGNS 77

Query: 1972 NHAKKSPNTS-----TLSQKRRIPIPEDSDDEIPLSSKFQVKSNAGESINRSSNSGERKP 1808
            +H +   N S     T  + R I  PED   E+ LSS+ Q+  NAG S   SS+S E KP
Sbjct: 78   HHIRMGSNLSCPSPYTSPKPRIIKGPED---EMLLSSELQL--NAGASNAESSDSDESKP 132

Query: 1807 LLSKYDQNGSASTERKPSTNLKKRPGDGVKTTDESYLKKPKLSEAATPHKNKEASIKAEM 1628
            L S+ ++         PS++L KRP    K +D S  KK KLSE + P   K    KAE 
Sbjct: 133  LASELEE---------PSSSLNKRPLIQPKISDPSPSKKAKLSEPSAPTNRKRKQPKAEE 183

Query: 1627 REEDDEDHVPISHRMXXXXXXXXXXXXXKNITKPIXXXXXXXXXXXXXXXXXXXXXXXXX 1448
               DD+  +PIS+R                  K                           
Sbjct: 184  AAADDD--LPISNRNKKSTTPASKVSD-----KKKRPDVSASLNKVNKQSNKADFSKSLK 236

Query: 1447 XXXXSGEGQKWTTLVHNGVIFPPPYKPHGVKMLYKGKPVDLTPEQEEVATMYAVMLETDY 1268
                SGEGQKWTTLVHNGVIFPP YKPHGVKMLYKG PVDLTPEQEEVATM+AVMLET+Y
Sbjct: 237  VPPGSGEGQKWTTLVHNGVIFPPLYKPHGVKMLYKGNPVDLTPEQEEVATMFAVMLETEY 296

Query: 1267 MNKPKFKENFMADWRKILGKNHTIQSLEHCDFTPIYEWHXXXXXXXXXXXXXXXXXXXXX 1088
            M KPKF+ENFM+DWRKILG+ H IQ+LE CDFTPIYEWH                     
Sbjct: 297  MTKPKFRENFMSDWRKILGEKHIIQNLEDCDFTPIYEWHQREKEKKKQMSTDEKKAIKEE 356

Query: 1087 XXXXXXKYMWAIVNGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIRPSDITINIGKDA 908
                  KY WA+V+GVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRI P+DITINIGKDA
Sbjct: 357  KMKQEEKYTWAVVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIFPNDITINIGKDA 416

Query: 907  PIPECPIPGESWKEIRHDNTVTWLAYWNDPINPKEFKYVFLAASSTLKGQSDKEKYEKAR 728
            PIPE PIPGE WKEIRHDNTVTWLA+WNDPINPKEFKYVFLAASS+LKGQSDKEKYEK+R
Sbjct: 417  PIPEPPIPGERWKEIRHDNTVTWLAFWNDPINPKEFKYVFLAASSSLKGQSDKEKYEKSR 476

Query: 727  LLKDYILGIRAAYTKDFTSKDPAKRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKV 548
             LKDYI GIRAAYTKDF SKD  +RQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKV
Sbjct: 477  KLKDYIEGIRAAYTKDFASKDSKRRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKV 536

Query: 547  ENVEPVPPNTLKFDFLGKDSIRYQNEVEVETAVFKAIQQFRSGKKGGDDLFDRLDTSKLN 368
            ENVE   PN LKFDFLGKDSIRYQNEVEVE  VF AI+QFRSGK+GGDDLFD+LDTSKLN
Sbjct: 537  ENVETKRPNILKFDFLGKDSIRYQNEVEVEPRVFSAIEQFRSGKEGGDDLFDQLDTSKLN 596

Query: 367  AHLKELMPGLTAKVFRTYNASITLDDMLSRETRGGDVAEKVVVYQHANKEVAIICNHQRT 188
            AHLKELMPGLTAKVFRTYNASITLD+MLSRET+GGDVAEKVVVYQHANKEVAIICNHQRT
Sbjct: 597  AHLKELMPGLTAKVFRTYNASITLDEMLSRETKGGDVAEKVVVYQHANKEVAIICNHQRT 656

Query: 187  VSKSHSAQMLRLNEKIEELKGVVEELQTDLARAKKGKPPLKSADGKPKRNLNPDALERKI 8
            VSKSHSAQM+RLNEKIEELKG+++ELQ DL R  KGKPPLK++DGKPKRNLNP+AL+RKI
Sbjct: 657  VSKSHSAQMVRLNEKIEELKGLLKELQEDLTRVNKGKPPLKNSDGKPKRNLNPEALQRKI 716

Query: 7    AQ 2
            AQ
Sbjct: 717  AQ 718