BLASTX 2.2.26 [Sep-21-2011]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= Rehmannia29_contig00001172
         (2538 letters)

Database: All non-redundant GenBank CDS
translations+PDB+SwissProt+PIR+PRF excluding environmental samples
from WGS projects 
           149,584,005 sequences; 54,822,741,787 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

ref|XP_012838234.1| PREDICTED: nicastrin [Erythranthe guttata] >...  1109   0.0  
ref|XP_011085876.1| nicastrin [Sesamum indicum]                      1034   0.0  
gb|PIN06941.1| Transmembrane glycoprotein nicastrin [Handroanthu...  1008   0.0  
gb|KZV53792.1| nicastrin [Dorcoceras hygrometricum]                   959   0.0  
ref|XP_022884594.1| nicastrin isoform X2 [Olea europaea var. syl...   958   0.0  
ref|XP_022884593.1| nicastrin isoform X1 [Olea europaea var. syl...   950   0.0  
ref|XP_009758540.1| PREDICTED: nicastrin isoform X2 [Nicotiana s...   913   0.0  
ref|XP_019223514.1| PREDICTED: nicastrin isoform X2 [Nicotiana a...   909   0.0  
ref|XP_009758539.1| PREDICTED: nicastrin isoform X1 [Nicotiana s...   909   0.0  
ref|XP_009626875.1| PREDICTED: nicastrin isoform X2 [Nicotiana t...   907   0.0  
ref|XP_016488669.1| PREDICTED: nicastrin-like isoform X2 [Nicoti...   907   0.0  
ref|XP_019223513.1| PREDICTED: nicastrin isoform X1 [Nicotiana a...   905   0.0  
ref|XP_009626874.1| PREDICTED: nicastrin isoform X1 [Nicotiana t...   903   0.0  
ref|XP_016488668.1| PREDICTED: nicastrin-like isoform X1 [Nicoti...   902   0.0  
ref|XP_006352434.1| PREDICTED: nicastrin isoform X2 [Solanum tub...   894   0.0  
ref|XP_006352433.1| PREDICTED: nicastrin isoform X1 [Solanum tub...   890   0.0  
ref|XP_016551191.1| PREDICTED: nicastrin isoform X2 [Capsicum an...   888   0.0  
ref|XP_004250204.1| PREDICTED: nicastrin isoform X2 [Solanum lyc...   885   0.0  
ref|XP_015058798.1| PREDICTED: nicastrin isoform X2 [Solanum pen...   885   0.0  
ref|XP_002264144.1| PREDICTED: nicastrin [Vitis vinifera] >gi|29...   884   0.0  

>ref|XP_012838234.1| PREDICTED: nicastrin [Erythranthe guttata]
 gb|EYU45769.1| hypothetical protein MIMGU_mgv1a002472mg [Erythranthe guttata]
          Length = 669

 Score = 1109 bits (2869), Expect = 0.0
 Identities = 559/671 (83%), Positives = 601/671 (89%)
 Frame = -1

Query: 2115 MGSKXXXXXXXLCFVTRLGFSFSASGKTNSFESVPDLEKSMYTQIDGFPCVRLLNLSGEI 1936
            M SK       LC + RL  SFSASG+T SFESVPDLEKSMYT+I+GFPCVRLLNLSGEI
Sbjct: 1    MDSKLSLLFSLLCLIARLRLSFSASGETKSFESVPDLEKSMYTEIEGFPCVRLLNLSGEI 60

Query: 1935 GCSNPGRGNVVAPIVRFKNANEFVGPAAILVSLDEFESLLSRVSNDPDFARKVAGILVES 1756
            GCSNPGRGNVVAPIVRFKNA E +G A ILVS+DEFESLLSRVS D +FA KV GILVES
Sbjct: 61   GCSNPGRGNVVAPIVRFKNAKELIGSATILVSVDEFESLLSRVSKDSEFAEKVVGILVES 120

Query: 1755 TTQVQNGIKGFSPDVKFPQAGFAPYRSNNFEWNPAGSGIMWKAYNFPVFLLSKNSSSILQ 1576
             TQVQNG+ GFSPDVKFPQA FAPY+SNNFEWNPAGSGIMWK YNFPVFLLS+ S+SILQ
Sbjct: 121  GTQVQNGLSGFSPDVKFPQAAFAPYQSNNFEWNPAGSGIMWKPYNFPVFLLSQTSTSILQ 180

Query: 1575 EVALMNEKTKKAYTKVVSEFDLVMQTTKSGTHDSDSCLKEGTCLPLGGYSVWSALPPINI 1396
            EVAL NE++K +Y KVVSEFDLVMQTTKSGT DS+SCLKEGTCLPLGGYSVWSALPPINI
Sbjct: 181  EVALRNEESKSSYPKVVSEFDLVMQTTKSGTRDSNSCLKEGTCLPLGGYSVWSALPPINI 240

Query: 1395 SSPLKAKPVVLTMTSMDSASFFRDKNLGAESPISGLIALLAVVDSLSRLGGLEELNKQLV 1216
            SSP+KAKP+VLTMTSMDSASFFRDKNLGAE+PISGLIALLAVVD+LS   GL++LNKQLV
Sbjct: 241  SSPVKAKPIVLTMTSMDSASFFRDKNLGAETPISGLIALLAVVDALSHFDGLKDLNKQLV 300

Query: 1215 FVVLTGEAWGYLGSRRFFLESDQQSDTMKGLDLAMIETVVEIGSVGKSYPQGTKTFFAHT 1036
            FVV TGEAWGYLGSRRFFLES+QQSDT+KGLDLAMIETV+EIGSVGKS+P+ +KTFFAHT
Sbjct: 301  FVVFTGEAWGYLGSRRFFLESEQQSDTIKGLDLAMIETVMEIGSVGKSFPESSKTFFAHT 360

Query: 1035 AGATSSVNGTLNALQHAQDSLITESIMVKTASTSNPGVPPSSLMTFLRKKPQISGLVLED 856
            AGA SS+NGTLNALQ AQ+SL TESI+VKTASTSNPGVPPSSLMTFLRKKPQISGLVLED
Sbjct: 361  AGAKSSLNGTLNALQSAQESLKTESIIVKTASTSNPGVPPSSLMTFLRKKPQISGLVLED 420

Query: 855  FDSAFSNEFYHSHLDDLSNINSTSIVAAASLVARTLYILAGGKDPSAINNIKINSSFVEE 676
            FDSAFSNEFYHSHLDDLSNINSTSIVAAASLVAR+LYILAGGKDPSAI++IKIN+S V+E
Sbjct: 421  FDSAFSNEFYHSHLDDLSNINSTSIVAAASLVARSLYILAGGKDPSAISSIKINASLVDE 480

Query: 675  LLGCLLDCEPGLSCGLVKHYISPSTTCPSHYVGVILGEPSSKPYPAYAGDISRFVWNFLA 496
            LLGCLL+CEPGLSCGLVK YISPSTTCP+HYVGVILGEPSS+PYPAYAGDISRFVWNFLA
Sbjct: 481  LLGCLLNCEPGLSCGLVKRYISPSTTCPNHYVGVILGEPSSEPYPAYAGDISRFVWNFLA 540

Query: 495  DKTSIPSKNLSSSCSKDCNGDNELCIREEADGKGVCVISTTRFVPAYSTRLKYDDESGSW 316
            DKTSIPSKN+SSSC KDC GD ELCIREEADGKGVCV+STTRFVPAYSTRLKY  ES SW
Sbjct: 541  DKTSIPSKNVSSSCPKDCKGDGELCIREEADGKGVCVVSTTRFVPAYSTRLKY--ESESW 598

Query: 315  TVLPSNSSDIMGVEDPVWTESNWDVINVRVYTVQTAAYDHXXXXXXXXXXXXXXXXXXIA 136
            TVLP NS+DIMGVEDPVWTESNWD I VRVYTVQ  A+D                   IA
Sbjct: 599  TVLPLNSTDIMGVEDPVWTESNWDTIKVRVYTVQNTAFDRLILLLGIIVTLLAYLLIVIA 658

Query: 135  RTVIRKALKQD 103
            RTVIRKALKQD
Sbjct: 659  RTVIRKALKQD 669


>ref|XP_011085876.1| nicastrin [Sesamum indicum]
          Length = 668

 Score = 1034 bits (2674), Expect = 0.0
 Identities = 522/659 (79%), Positives = 575/659 (87%)
 Frame = -1

Query: 2079 CFVTRLGFSFSASGKTNSFESVPDLEKSMYTQIDGFPCVRLLNLSGEIGCSNPGRGNVVA 1900
            CF+     S SASG+T SFESVPDLEKSMY +I+GFPCVRLLNLSGEIGCSNPGR  VVA
Sbjct: 13   CFLALFRLSSSASGETKSFESVPDLEKSMYKEIEGFPCVRLLNLSGEIGCSNPGREKVVA 72

Query: 1899 PIVRFKNANEFVGPAAILVSLDEFESLLSRVSNDPDFARKVAGILVESTTQVQNGIKGFS 1720
            PIVRF+NA EFVG AAILVS+DEFESLLSRV  D  F+ KVAGILVES+T VQN   GFS
Sbjct: 73   PIVRFQNAKEFVGSAAILVSIDEFESLLSRVLKDSAFSSKVAGILVESSTPVQNARMGFS 132

Query: 1719 PDVKFPQAGFAPYRSNNFEWNPAGSGIMWKAYNFPVFLLSKNSSSILQEVALMNEKTKKA 1540
            PDVKFPQA FAPY+SNNFEWNP G+G+MWK YNFPVFLLS+ S+SILQE ALMNEK++ +
Sbjct: 133  PDVKFPQAEFAPYQSNNFEWNPDGTGVMWKNYNFPVFLLSETSTSILQEAALMNEKSEMS 192

Query: 1539 YTKVVSEFDLVMQTTKSGTHDSDSCLKEGTCLPLGGYSVWSALPPINISSPLKAKPVVLT 1360
            YT+ V+EFDLVMQTTKS THDS+SCLKEGTCLPLGGYSVWSALPPINISS LKAKP++L 
Sbjct: 193  YTENVAEFDLVMQTTKSSTHDSESCLKEGTCLPLGGYSVWSALPPINISSSLKAKPIILA 252

Query: 1359 MTSMDSASFFRDKNLGAESPISGLIALLAVVDSLSRLGGLEELNKQLVFVVLTGEAWGYL 1180
            MTSMDSASFFRD++LGAESPISGLIALLAVVD+LS L GLEELNKQLVFVVLTGE+WGYL
Sbjct: 253  MTSMDSASFFRDRSLGAESPISGLIALLAVVDALSHLDGLEELNKQLVFVVLTGESWGYL 312

Query: 1179 GSRRFFLESDQQSDTMKGLDLAMIETVVEIGSVGKSYPQGTKTFFAHTAGATSSVNGTLN 1000
            GSRRFFLESD+QSD MKGLDLAM+E V+EIGSVGKS+ QG KTFFAHTAGA SSVNGT N
Sbjct: 313  GSRRFFLESDKQSDAMKGLDLAMLEMVLEIGSVGKSFSQGNKTFFAHTAGAASSVNGTFN 372

Query: 999  ALQHAQDSLITESIMVKTASTSNPGVPPSSLMTFLRKKPQISGLVLEDFDSAFSNEFYHS 820
             LQ AQDSL+TESIMVK AST+NPGVPPSSLMTFLRKKPQISG VLEDFDS FSN+FYHS
Sbjct: 373  VLQRAQDSLVTESIMVKRASTTNPGVPPSSLMTFLRKKPQISGFVLEDFDSTFSNKFYHS 432

Query: 819  HLDDLSNINSTSIVAAASLVARTLYILAGGKDPSAINNIKINSSFVEELLGCLLDCEPGL 640
            HLD+LSNI+ +SIVAAASLVARTLYILAGGKD SAIN IK+N+S VEELLGCLL CEPGL
Sbjct: 433  HLDELSNISPSSIVAAASLVARTLYILAGGKD-SAINTIKVNASLVEELLGCLLACEPGL 491

Query: 639  SCGLVKHYISPSTTCPSHYVGVILGEPSSKPYPAYAGDISRFVWNFLADKTSIPSKNLSS 460
            SCGLVKHYISPSTTCPSHYVGVILGEPSS  YPAYAGD+SRFVWNFLADKTSI  +N+ S
Sbjct: 492  SCGLVKHYISPSTTCPSHYVGVILGEPSSALYPAYAGDVSRFVWNFLADKTSISLRNVGS 551

Query: 459  SCSKDCNGDNELCIREEADGKGVCVISTTRFVPAYSTRLKYDDESGSWTVLPSNSSDIMG 280
            SC+K C+G  ELCIR EADGKGVCVISTTR+VPAYSTRLKY  ESGSW VLP+NSSD M 
Sbjct: 552  SCAKACSGVGELCIRGEADGKGVCVISTTRYVPAYSTRLKY--ESGSWIVLPNNSSDNMD 609

Query: 279  VEDPVWTESNWDVINVRVYTVQTAAYDHXXXXXXXXXXXXXXXXXXIARTVIRKALKQD 103
            V+DPVWTESNWD+I VR+Y VQ ++YD+                  IA++VIRKALKQ+
Sbjct: 610  VDDPVWTESNWDIIKVRMYRVQNSSYDYLILLLGIIVTLLAYILIEIAKSVIRKALKQE 668


>gb|PIN06941.1| Transmembrane glycoprotein nicastrin [Handroanthus impetiginosus]
          Length = 595

 Score = 1008 bits (2605), Expect = 0.0
 Identities = 500/597 (83%), Positives = 546/597 (91%)
 Frame = -1

Query: 1995 MYTQIDGFPCVRLLNLSGEIGCSNPGRGNVVAPIVRFKNANEFVGPAAILVSLDEFESLL 1816
            MYTQ++GFPCVRLLNLSGEIGCSNPGRG VVAPIVRF+NA E VG AAILVS+DEFESLL
Sbjct: 1    MYTQVEGFPCVRLLNLSGEIGCSNPGRGKVVAPIVRFENAKELVGSAAILVSVDEFESLL 60

Query: 1815 SRVSNDPDFARKVAGILVESTTQVQNGIKGFSPDVKFPQAGFAPYRSNNFEWNPAGSGIM 1636
            SR+S D +F RKVAGILVES+TQV N +KGFSPDVKFPQA FAPY+SNNFEWNP+GSGIM
Sbjct: 61   SRLSKDSEFVRKVAGILVESSTQVSNDLKGFSPDVKFPQAEFAPYQSNNFEWNPSGSGIM 120

Query: 1635 WKAYNFPVFLLSKNSSSILQEVALMNEKTKKAYTKVVSEFDLVMQTTKSGTHDSDSCLKE 1456
            WKAYNFPVFLLS+ S+SILQE AL N K KK+Y + V+EFDLVMQTTKSGTH+SDSCLKE
Sbjct: 121  WKAYNFPVFLLSQTSTSILQEAALRNVKNKKSYIETVAEFDLVMQTTKSGTHNSDSCLKE 180

Query: 1455 GTCLPLGGYSVWSALPPINISSPLKAKPVVLTMTSMDSASFFRDKNLGAESPISGLIALL 1276
            G+CLPLGGYSVWSALPPINIS   KAKP+VLTMTSMDSASFFRDKNLGA+SPISGLIALL
Sbjct: 181  GSCLPLGGYSVWSALPPINISYSPKAKPIVLTMTSMDSASFFRDKNLGAQSPISGLIALL 240

Query: 1275 AVVDSLSRLGGLEELNKQLVFVVLTGEAWGYLGSRRFFLESDQQSDTMKGLDLAMIETVV 1096
            AVVD+LSRL GL+EL+KQLVF+VLTGEAWGY+GSRR FLE DQQSD+MKGLDLA I+TV+
Sbjct: 241  AVVDALSRLDGLQELHKQLVFMVLTGEAWGYIGSRRLFLEFDQQSDSMKGLDLATIDTVL 300

Query: 1095 EIGSVGKSYPQGTKTFFAHTAGATSSVNGTLNALQHAQDSLITESIMVKTASTSNPGVPP 916
            EIGSVGK  PQG  TFFAH +GATSSVNGTL+AL+ AQD+L  ESI+VKTASTSNPGVPP
Sbjct: 301  EIGSVGKGSPQGINTFFAHASGATSSVNGTLDALKRAQDALRNESIIVKTASTSNPGVPP 360

Query: 915  SSLMTFLRKKPQISGLVLEDFDSAFSNEFYHSHLDDLSNINSTSIVAAASLVARTLYILA 736
            SSLMTFLRKKP+ISGLVLEDFDSAFSN+FYHSHLDDLSNINS+SIVAAASLV+RTLY LA
Sbjct: 361  SSLMTFLRKKPKISGLVLEDFDSAFSNKFYHSHLDDLSNINSSSIVAAASLVSRTLYTLA 420

Query: 735  GGKDPSAINNIKINSSFVEELLGCLLDCEPGLSCGLVKHYISPSTTCPSHYVGVILGEPS 556
            GGKD S +NNIKINSS VEELLGCLLDCEPGLSCGLVKHYISP+TTCPSHYVGVILGEPS
Sbjct: 421  GGKDSSVMNNIKINSSLVEELLGCLLDCEPGLSCGLVKHYISPATTCPSHYVGVILGEPS 480

Query: 555  SKPYPAYAGDISRFVWNFLADKTSIPSKNLSSSCSKDCNGDNELCIREEADGKGVCVIST 376
            S+PYP YAGDISRFVWNFLADKTSI S+N SSSC KDC+GD ELCIR+EADGKGVCVIST
Sbjct: 481  SEPYPPYAGDISRFVWNFLADKTSIQSRNGSSSCPKDCSGDGELCIRQEADGKGVCVIST 540

Query: 375  TRFVPAYSTRLKYDDESGSWTVLPSNSSDIMGVEDPVWTESNWDVINVRVYTVQTAA 205
            TR+VPAYS RLKY  ES SWTVLPSN+S+ +  EDPVWTESNWD I VRVYTVQ AA
Sbjct: 541  TRYVPAYSARLKY--ESDSWTVLPSNTSETVDAEDPVWTESNWDTIKVRVYTVQNAA 595


>gb|KZV53792.1| nicastrin [Dorcoceras hygrometricum]
          Length = 669

 Score =  959 bits (2478), Expect = 0.0
 Identities = 478/671 (71%), Positives = 554/671 (82%)
 Frame = -1

Query: 2115 MGSKXXXXXXXLCFVTRLGFSFSASGKTNSFESVPDLEKSMYTQIDGFPCVRLLNLSGEI 1936
            M SK       L FV     S SA GKT+SFESVPDLEKSMY QIDG+PCVRLLN+SGEI
Sbjct: 1    MKSKLPVFLPLLFFVALFHPSISAPGKTSSFESVPDLEKSMYKQIDGYPCVRLLNISGEI 60

Query: 1935 GCSNPGRGNVVAPIVRFKNANEFVGPAAILVSLDEFESLLSRVSNDPDFARKVAGILVES 1756
            GCSNPGRG VVAPIV+FKNAN  +   AILVS+++FESLLSRVS DPDF+R VAG+LVE+
Sbjct: 61   GCSNPGRGKVVAPIVQFKNANVLIRSTAILVSVNDFESLLSRVSKDPDFSRNVAGVLVEA 120

Query: 1755 TTQVQNGIKGFSPDVKFPQAGFAPYRSNNFEWNPAGSGIMWKAYNFPVFLLSKNSSSILQ 1576
            +TQVQNG+   SPDVKFPQA FAPY+SNNFEWNPAGSGIMWKA+NFPVFLLS++S+ ILQ
Sbjct: 121  STQVQNGLNRNSPDVKFPQAEFAPYKSNNFEWNPAGSGIMWKAFNFPVFLLSESSTPILQ 180

Query: 1575 EVALMNEKTKKAYTKVVSEFDLVMQTTKSGTHDSDSCLKEGTCLPLGGYSVWSALPPINI 1396
            E  L N+K K +YT+ V EFDLVM TTKSG  DSD+CL++G CLPLGGYSVWSALPP++I
Sbjct: 181  EAVLANDKRKTSYTEDVVEFDLVMDTTKSGNLDSDACLRDGACLPLGGYSVWSALPPVSI 240

Query: 1395 SSPLKAKPVVLTMTSMDSASFFRDKNLGAESPISGLIALLAVVDSLSRLGGLEELNKQLV 1216
            SS  K KP+VLT+TSMDSASFFRDK+LGA+SPISGLI LLA VD++S +  L+EL+KQLV
Sbjct: 241  SSSPKTKPLVLTVTSMDSASFFRDKSLGADSPISGLITLLAAVDAISHVQKLDELDKQLV 300

Query: 1215 FVVLTGEAWGYLGSRRFFLESDQQSDTMKGLDLAMIETVVEIGSVGKSYPQGTKTFFAHT 1036
            F+VLTGEAWGYLGSRRF LESDQ SD +KGLD+AM+E V+EIGSVGKS+ QG KT + HT
Sbjct: 301  FLVLTGEAWGYLGSRRFLLESDQHSDAIKGLDMAMVEMVLEIGSVGKSFSQGMKTLYTHT 360

Query: 1035 AGATSSVNGTLNALQHAQDSLITESIMVKTASTSNPGVPPSSLMTFLRKKPQISGLVLED 856
            +G TSSV+GTLNA+Q AQDS  T+ I+VK ASTSNPGVPPSSLMTFLRK  QISG+VLED
Sbjct: 361  SGDTSSVHGTLNAIQRAQDSFKTDGIVVKRASTSNPGVPPSSLMTFLRKNHQISGVVLED 420

Query: 855  FDSAFSNEFYHSHLDDLSNINSTSIVAAASLVARTLYILAGGKDPSAINNIKINSSFVEE 676
            FDSAF+N+FYHSHLDDLSN+NS++IV+AA+LVARTLYI AGG + S +++I +N+S VEE
Sbjct: 421  FDSAFTNKFYHSHLDDLSNVNSSAIVSAAALVARTLYIAAGGNNDSVMSSINVNASMVEE 480

Query: 675  LLGCLLDCEPGLSCGLVKHYISPSTTCPSHYVGVILGEPSSKPYPAYAGDISRFVWNFLA 496
            LL CLL CEPGLSC LVKHYISPS+TCPSHYVGV+LGEPSS P PAY GD+SRFVWNFLA
Sbjct: 481  LLSCLLKCEPGLSCDLVKHYISPSSTCPSHYVGVVLGEPSSAPNPAYVGDVSRFVWNFLA 540

Query: 495  DKTSIPSKNLSSSCSKDCNGDNELCIREEADGKGVCVISTTRFVPAYSTRLKYDDESGSW 316
            DKTS PSK+ SS+C  DC    ELCI+ E DGKGVCV+STTR+VPAYSTRLKY  ESG W
Sbjct: 541  DKTSTPSKSTSSACPNDCKDVGELCIKTENDGKGVCVVSTTRYVPAYSTRLKY--ESGGW 598

Query: 315  TVLPSNSSDIMGVEDPVWTESNWDVINVRVYTVQTAAYDHXXXXXXXXXXXXXXXXXXIA 136
            T+LP NSSD M +EDPVWTESNWD I ++VY+VQ A YD                   I 
Sbjct: 599  TLLPYNSSDTMSMEDPVWTESNWDTIGLKVYSVQDATYDCLILALGILITLLAYLLILIV 658

Query: 135  RTVIRKALKQD 103
            RT+IRKALKQ+
Sbjct: 659  RTLIRKALKQE 669


>ref|XP_022884594.1| nicastrin isoform X2 [Olea europaea var. sylvestris]
          Length = 667

 Score =  958 bits (2477), Expect = 0.0
 Identities = 479/653 (73%), Positives = 545/653 (83%)
 Frame = -1

Query: 2061 GFSFSASGKTNSFESVPDLEKSMYTQIDGFPCVRLLNLSGEIGCSNPGRGNVVAPIVRFK 1882
            G SFS SG+ NSFESVPDLEKSMY  +DG+PCVR+LNLSGEIGCSNP R  VVAPIVR+K
Sbjct: 17   GLSFSDSGQENSFESVPDLEKSMYMHVDGYPCVRVLNLSGEIGCSNPSREKVVAPIVRYK 76

Query: 1881 NANEFVGPAAILVSLDEFESLLSRVSNDPDFARKVAGILVESTTQVQNGIKGFSPDVKFP 1702
            +A+E +  AA+LVS+DEFE LLSR+S D DFA KVAGILVES T+V NG+KGFSPD KFP
Sbjct: 77   SADELLKSAAVLVSIDEFEILLSRLSKDLDFAGKVAGILVESRTEVSNGLKGFSPDGKFP 136

Query: 1701 QAGFAPYRSNNFEWNPAGSGIMWKAYNFPVFLLSKNSSSILQEVALMNEKTKKAYTKVVS 1522
            QA FAPY+SNNF WNP GSGIMWKAYNFPVFLLS+ S+ ILQEV + NEKTKK+ T+ V+
Sbjct: 137  QAEFAPYQSNNFTWNPPGSGIMWKAYNFPVFLLSRTSTLILQEVVMKNEKTKKSNTENVA 196

Query: 1521 EFDLVMQTTKSGTHDSDSCLKEGTCLPLGGYSVWSALPPINISSPLKAKPVVLTMTSMDS 1342
            EF++VMQTTKSGTHDSDSCLKE TCLPLGGYSVWSALPPINISS  K+KPV++TMTSMDS
Sbjct: 197  EFNVVMQTTKSGTHDSDSCLKEETCLPLGGYSVWSALPPINISSSQKSKPVIVTMTSMDS 256

Query: 1341 ASFFRDKNLGAESPISGLIALLAVVDSLSRLGGLEELNKQLVFVVLTGEAWGYLGSRRFF 1162
            ASFFRDK+LGA+SPISGLI LLA VD+LS L GL+ELNKQLVFVVLTGE+WGYLGSRRF 
Sbjct: 257  ASFFRDKSLGADSPISGLITLLAAVDALSYLDGLDELNKQLVFVVLTGESWGYLGSRRFV 316

Query: 1161 LESDQQSDTMKGLDLAMIETVVEIGSVGKSYPQGTKTFFAHTAGATSSVNGTLNALQHAQ 982
            LE+DQ SD+++GLD AMIETV+EIGSVGK    G KTF++HT+G T + N T  AL  AQ
Sbjct: 317  LEADQHSDSVRGLDFAMIETVMEIGSVGKGLSNGVKTFYSHTSGDTLATNETFQALLRAQ 376

Query: 981  DSLITESIMVKTASTSNPGVPPSSLMTFLRKKPQISGLVLEDFDSAFSNEFYHSHLDDLS 802
            DSL TESI +  ASTSNPGVPPSSLMTFLRKK QISG+VLEDFD++F+N+FYHSHLDDLS
Sbjct: 377  DSLKTESIKISMASTSNPGVPPSSLMTFLRKKSQISGVVLEDFDTSFTNKFYHSHLDDLS 436

Query: 801  NINSTSIVAAASLVARTLYILAGGKDPSAINNIKINSSFVEELLGCLLDCEPGLSCGLVK 622
            N+NS++IV AASLVARTLY+LA  ++ SAIN I +N+S VEELLGCLL+C+PG SC L+K
Sbjct: 437  NVNSSAIVTAASLVARTLYLLANDQNASAINAINVNASLVEELLGCLLNCKPGSSCELMK 496

Query: 621  HYISPSTTCPSHYVGVILGEPSSKPYPAYAGDISRFVWNFLADKTSIPSKNLSSSCSKDC 442
            HYISPS TCPSHYVGVILGEPSS PYPAY  D+SRFVWNFLA KTSI S+N++S+C  DC
Sbjct: 497  HYISPSATCPSHYVGVILGEPSSVPYPAYVSDVSRFVWNFLASKTSIFSRNITSACPNDC 556

Query: 441  NGDNELCIREEADGKGVCVISTTRFVPAYSTRLKYDDESGSWTVLPSNSSDIMGVEDPVW 262
            NG  ELCIREEADGKG+CVISTTR+VPAYSTRLKY  ESGSWTVLP NSS+ M   DPVW
Sbjct: 557  NGVGELCIREEADGKGICVISTTRYVPAYSTRLKY--ESGSWTVLPYNSSEEMSAADPVW 614

Query: 261  TESNWDVINVRVYTVQTAAYDHXXXXXXXXXXXXXXXXXXIARTVIRKALKQD 103
            TESNWD I++RVY VQ  AYD                   I R  IRKALK D
Sbjct: 615  TESNWDTISLRVYKVQNTAYDGLILLSGIVVTVLTYLLILITRAFIRKALKWD 667


>ref|XP_022884593.1| nicastrin isoform X1 [Olea europaea var. sylvestris]
          Length = 678

 Score =  950 bits (2455), Expect = 0.0
 Identities = 479/664 (72%), Positives = 545/664 (82%), Gaps = 11/664 (1%)
 Frame = -1

Query: 2061 GFSFSASGKTNSFESVPDLEKSMYTQIDGFPCVRLLNLSGEIGCSNPGRGNVVAPIVRFK 1882
            G SFS SG+ NSFESVPDLEKSMY  +DG+PCVR+LNLSGEIGCSNP R  VVAPIVR+K
Sbjct: 17   GLSFSDSGQENSFESVPDLEKSMYMHVDGYPCVRVLNLSGEIGCSNPSREKVVAPIVRYK 76

Query: 1881 NANEFVGPAAILVSLDEFESLLSRVSNDPDFARKVAGILVESTTQVQNGIKGFSPDVKFP 1702
            +A+E +  AA+LVS+DEFE LLSR+S D DFA KVAGILVES T+V NG+KGFSPD KFP
Sbjct: 77   SADELLKSAAVLVSIDEFEILLSRLSKDLDFAGKVAGILVESRTEVSNGLKGFSPDGKFP 136

Query: 1701 QAGFAPYRSNNFEWNPAGSGIMWKAYNFPVFLLSKNSSSILQEVALMNEKTKKAYTKVVS 1522
            QA FAPY+SNNF WNP GSGIMWKAYNFPVFLLS+ S+ ILQEV + NEKTKK+ T+ V+
Sbjct: 137  QAEFAPYQSNNFTWNPPGSGIMWKAYNFPVFLLSRTSTLILQEVVMKNEKTKKSNTENVA 196

Query: 1521 EFDLVMQTTKSGTHDSDSCLKEGTCLPLGGYSVWSALPPINISSPLKAKPVVLTMTSMDS 1342
            EF++VMQTTKSGTHDSDSCLKE TCLPLGGYSVWSALPPINISS  K+KPV++TMTSMDS
Sbjct: 197  EFNVVMQTTKSGTHDSDSCLKEETCLPLGGYSVWSALPPINISSSQKSKPVIVTMTSMDS 256

Query: 1341 ASFFRDKNLGAESPISGLIALLAVVDSLSRLGGLEELNKQLVFVVLTGEAWGYLGSRRFF 1162
            ASFFRDK+LGA+SPISGLI LLA VD+LS L GL+ELNKQLVFVVLTGE+WGYLGSRRF 
Sbjct: 257  ASFFRDKSLGADSPISGLITLLAAVDALSYLDGLDELNKQLVFVVLTGESWGYLGSRRFV 316

Query: 1161 LESDQQSDTMKGLDLAMIETVVEIGSVGKSYPQGTKTFFAHTAGATSSVNGTLNALQHAQ 982
            LE+DQ SD+++GLD AMIETV+EIGSVGK    G KTF++HT+G T + N T  AL  AQ
Sbjct: 317  LEADQHSDSVRGLDFAMIETVMEIGSVGKGLSNGVKTFYSHTSGDTLATNETFQALLRAQ 376

Query: 981  DSLITESIMVKTASTSNPGVPPSSLMTFLRKKPQISGLVLEDFDSAFSNEFYHSHLDDLS 802
            DSL TESI +  ASTSNPGVPPSSLMTFLRKK QISG+VLEDFD++F+N+FYHSHLDDLS
Sbjct: 377  DSLKTESIKISMASTSNPGVPPSSLMTFLRKKSQISGVVLEDFDTSFTNKFYHSHLDDLS 436

Query: 801  NINSTSIVAAASLVARTLYILAGGKDPSAINNIKINSSFVEELLGCLLDCEPGLSCGLVK 622
            N+NS++IV AASLVARTLY+LA  ++ SAIN I +N+S VEELLGCLL+C+PG SC L+K
Sbjct: 437  NVNSSAIVTAASLVARTLYLLANDQNASAINAINVNASLVEELLGCLLNCKPGSSCELMK 496

Query: 621  HYISPSTTCPSHYVGVILGEPSSKPYPAYAGDISRFVWNFLADKTSIPSKNLSSSCSKDC 442
            HYISPS TCPSHYVGVILGEPSS PYPAY  D+SRFVWNFLA KTSI S+N++S+C  DC
Sbjct: 497  HYISPSATCPSHYVGVILGEPSSVPYPAYVSDVSRFVWNFLASKTSIFSRNITSACPNDC 556

Query: 441  NGDNELCIREEADGKGVCVIST-----------TRFVPAYSTRLKYDDESGSWTVLPSNS 295
            NG  ELCIREEADGKG+CVIST           TR+VPAYSTRLKY  ESGSWTVLP NS
Sbjct: 557  NGVGELCIREEADGKGICVISTTRCLFLPFFYFTRYVPAYSTRLKY--ESGSWTVLPYNS 614

Query: 294  SDIMGVEDPVWTESNWDVINVRVYTVQTAAYDHXXXXXXXXXXXXXXXXXXIARTVIRKA 115
            S+ M   DPVWTESNWD I++RVY VQ  AYD                   I R  IRKA
Sbjct: 615  SEEMSAADPVWTESNWDTISLRVYKVQNTAYDGLILLSGIVVTVLTYLLILITRAFIRKA 674

Query: 114  LKQD 103
            LK D
Sbjct: 675  LKWD 678


>ref|XP_009758540.1| PREDICTED: nicastrin isoform X2 [Nicotiana sylvestris]
 ref|XP_016500129.1| PREDICTED: nicastrin-like isoform X2 [Nicotiana tabacum]
          Length = 670

 Score =  913 bits (2360), Expect = 0.0
 Identities = 448/662 (67%), Positives = 537/662 (81%), Gaps = 3/662 (0%)
 Frame = -1

Query: 2079 CFVTRLGFSFSASGKTNSFESVPDLEKSMYTQIDGFPCVRLLNLSGEIGCSNPGRGNVVA 1900
            CF+ +   S SAS + NSF+SVPDLEKSMY  IDG+PCVRLLNLSGEIGCSNPGR N+VA
Sbjct: 12   CFIAQFCLSISASDQVNSFQSVPDLEKSMYMAIDGYPCVRLLNLSGEIGCSNPGRANIVA 71

Query: 1899 PIVRFKNANEFVGPAAILVSLDEFESLLSRVSNDPDFARKVAGILVESTTQVQNGIKGFS 1720
            P+ RFK AN+   P+A++VS+D+FE L  R+SND +F+R V G+LVES +Q+QNG+KGFS
Sbjct: 72   PVARFKTANKLAEPSALVVSIDQFEELFGRLSNDAEFSRHVVGVLVESGSQLQNGLKGFS 131

Query: 1719 PDVKFPQAGFAPYRSNNFEWNPAGSGIMWKAYNFPVFLLSKNSSSILQEVALMNEKTKKA 1540
            PD KFPQA FAPYRS +FEWNP GSG+MWKAYNFPVFLLS +S+S LQE+AL NEK KK+
Sbjct: 132  PDKKFPQAEFAPYRSGSFEWNPIGSGLMWKAYNFPVFLLSNSSTSALQEIALRNEKRKKS 191

Query: 1539 YTKVVSEFDLVMQTTKSGTHDSDSCLKEGTCLPLGGYSVWSALPPINISSPLKAKPVVLT 1360
            YT  V++F+LVMQTTKSGT DS+SCL+E TCLPLGGYSVWSALPP+ ISS  KAKPV+L 
Sbjct: 192  YTVDVADFNLVMQTTKSGTRDSESCLREQTCLPLGGYSVWSALPPMAISSSEKAKPVILV 251

Query: 1359 MTSMDSASFFRDKNLGAESPISGLIALLAVVDSLSRLGGLEELNKQLVFVVLTGEAWGYL 1180
            + SMD+ASFFRDK++GA+SPISGLI+LL VVD+LSR+ GL++L+KQLVF V TGEAWGYL
Sbjct: 252  VASMDAASFFRDKSIGADSPISGLISLLTVVDALSRVDGLKDLDKQLVFAVFTGEAWGYL 311

Query: 1179 GSRRFFLESDQQSDTMKGLDLAMIETVVEIGSVGKSYPQGTKTFFAHTAGATSSVNGTLN 1000
            GSRRF LE DQ SD + GLDLA+IETV+EIGSVGK + Q  KTFFAH+   T++ NGTL+
Sbjct: 312  GSRRFLLELDQHSDAVSGLDLALIETVLEIGSVGKGFAQDDKTFFAHSTSETAT-NGTLS 370

Query: 999  ALQHAQDSLITESIMVKTASTSNPGVPPSSLMTFLRKKPQISGLVLEDFDSAFSNEFYHS 820
            A+Q A  SL T+SI +  AS SNPG+PPSSLM+FL+K P+ SG+VLEDFD+AF+N+FYHS
Sbjct: 371  AIQDALGSLRTQSIKISRASKSNPGLPPSSLMSFLKKNPKTSGVVLEDFDTAFTNKFYHS 430

Query: 819  HLDDLSNINSTSIVAAASLVARTLYILAGGK---DPSAINNIKINSSFVEELLGCLLDCE 649
            HLDDL NINS++IVAAAS+VAR+LYILA  K     SA+N I IN+S VEELLGCLL CE
Sbjct: 431  HLDDLLNINSSAIVAAASVVARSLYILASNKKEIKTSALNTININASLVEELLGCLLSCE 490

Query: 648  PGLSCGLVKHYISPSTTCPSHYVGVILGEPSSKPYPAYAGDISRFVWNFLADKTSIPSKN 469
            PGLSC LV  YI+PST+CPSHYVGV+LGEPSS+PYP   GD+ RFVWNFLADKT+IPSKN
Sbjct: 491  PGLSCELVNRYIAPSTSCPSHYVGVVLGEPSSQPYPGNVGDVPRFVWNFLADKTAIPSKN 550

Query: 468  LSSSCSKDCNGDNELCIREEADGKGVCVISTTRFVPAYSTRLKYDDESGSWTVLPSNSSD 289
            LSS+C K C+G  E+C++ E DGKGVCVISTTR++PAYSTRLKY  ES +W VLP NSSD
Sbjct: 551  LSSTCPKGCSGKGEMCVKAETDGKGVCVISTTRYIPAYSTRLKY--ESDTWEVLPHNSSD 608

Query: 288  IMGVEDPVWTESNWDVINVRVYTVQTAAYDHXXXXXXXXXXXXXXXXXXIARTVIRKALK 109
            IMG  DPVWTESNW+ I +RVYTVQ   +D                   +A+  I KALK
Sbjct: 609  IMGEADPVWTESNWETIKLRVYTVQDTRFDTWILLLGIAVTVLSYIITVMAKAFITKALK 668

Query: 108  QD 103
            +D
Sbjct: 669  RD 670


>ref|XP_019223514.1| PREDICTED: nicastrin isoform X2 [Nicotiana attenuata]
          Length = 670

 Score =  909 bits (2349), Expect = 0.0
 Identities = 445/662 (67%), Positives = 538/662 (81%), Gaps = 3/662 (0%)
 Frame = -1

Query: 2079 CFVTRLGFSFSASGKTNSFESVPDLEKSMYTQIDGFPCVRLLNLSGEIGCSNPGRGNVVA 1900
            CF+ +   S SAS + NSF+SVPDLEKSMY  IDG+PCVRLLNLSGEIGCSNPGR N+VA
Sbjct: 12   CFIAQFCLSISASDQVNSFQSVPDLEKSMYMAIDGYPCVRLLNLSGEIGCSNPGRANIVA 71

Query: 1899 PIVRFKNANEFVGPAAILVSLDEFESLLSRVSNDPDFARKVAGILVESTTQVQNGIKGFS 1720
            P+ RFK AN+   P+A++VS+++FE L  R+SND +F+R V G+LVES +Q+QNG+KGFS
Sbjct: 72   PVARFKTANKLAEPSALMVSIEQFEELFGRLSNDAEFSRHVVGVLVESGSQLQNGLKGFS 131

Query: 1719 PDVKFPQAGFAPYRSNNFEWNPAGSGIMWKAYNFPVFLLSKNSSSILQEVALMNEKTKKA 1540
            PD KFPQA FAPY+S +FEWNP GSG+MWKAYNFPVFLLS +S+S LQE+AL NEK KK+
Sbjct: 132  PDKKFPQAEFAPYQSGHFEWNPIGSGLMWKAYNFPVFLLSNSSTSALQEIALRNEKRKKS 191

Query: 1539 YTKVVSEFDLVMQTTKSGTHDSDSCLKEGTCLPLGGYSVWSALPPINISSPLKAKPVVLT 1360
            YT  V++F+LVMQTTKSGT DS+SCL+E TCLPLGGYSVWSALPP+ ISS  KAKPV+L 
Sbjct: 192  YTVDVADFNLVMQTTKSGTRDSESCLREQTCLPLGGYSVWSALPPMAISSSEKAKPVILV 251

Query: 1359 MTSMDSASFFRDKNLGAESPISGLIALLAVVDSLSRLGGLEELNKQLVFVVLTGEAWGYL 1180
            + SMD+ASFFRDK++GA+SPISGLI+LLAVVD+LSR+ GL++L+KQLVF V TGEAWGYL
Sbjct: 252  VASMDAASFFRDKSIGADSPISGLISLLAVVDALSRVDGLKDLDKQLVFAVFTGEAWGYL 311

Query: 1179 GSRRFFLESDQQSDTMKGLDLAMIETVVEIGSVGKSYPQGTKTFFAHTAGATSSVNGTLN 1000
            GSRRF LE DQ SD + GLDLA+IETV+EIGSVGK + +  KTFFAH+   T++ NGTL+
Sbjct: 312  GSRRFLLELDQHSDAVSGLDLALIETVLEIGSVGKGFARDDKTFFAHSTSETAT-NGTLS 370

Query: 999  ALQHAQDSLITESIMVKTASTSNPGVPPSSLMTFLRKKPQISGLVLEDFDSAFSNEFYHS 820
            A+Q A  SL T+S  +  AS SNPG+PPSSLM+FL+K P+ SG+VLEDFD+AF+N+FYHS
Sbjct: 371  AIQDAVGSLKTQSTKISRASKSNPGLPPSSLMSFLKKNPKTSGVVLEDFDTAFTNKFYHS 430

Query: 819  HLDDLSNINSTSIVAAASLVARTLYILAGGK---DPSAINNIKINSSFVEELLGCLLDCE 649
            HLDDL NINS++IVAAAS+VAR+LYILA  K     SA+N I IN+S VEELLGCLL CE
Sbjct: 431  HLDDLLNINSSAIVAAASVVARSLYILASDKKEIKTSALNTININASLVEELLGCLLSCE 490

Query: 648  PGLSCGLVKHYISPSTTCPSHYVGVILGEPSSKPYPAYAGDISRFVWNFLADKTSIPSKN 469
            PGLSC LV  YI+PST+CPSHYVGV+LGEPSS+PYP   GD+ RFVWNFLADKT+IPSKN
Sbjct: 491  PGLSCELVNRYIAPSTSCPSHYVGVVLGEPSSQPYPGNVGDVPRFVWNFLADKTAIPSKN 550

Query: 468  LSSSCSKDCNGDNELCIREEADGKGVCVISTTRFVPAYSTRLKYDDESGSWTVLPSNSSD 289
            LSS+C K C+G+ E+C++ E DGKGVCVISTTR++PAYSTRLKY  ES +W VLP NSSD
Sbjct: 551  LSSTCPKGCSGNGEMCVKAETDGKGVCVISTTRYIPAYSTRLKY--ESDTWEVLPHNSSD 608

Query: 288  IMGVEDPVWTESNWDVINVRVYTVQTAAYDHXXXXXXXXXXXXXXXXXXIARTVIRKALK 109
            IMG  DPVWTESNW+ I +RVYTVQ   +D                   +A+  I KALK
Sbjct: 609  IMGEADPVWTESNWETIKLRVYTVQDTRFDTWILLLGIAVTVLSYIITVMAKAFITKALK 668

Query: 108  QD 103
            +D
Sbjct: 669  RD 670


>ref|XP_009758539.1| PREDICTED: nicastrin isoform X1 [Nicotiana sylvestris]
 ref|XP_016500128.1| PREDICTED: nicastrin-like isoform X1 [Nicotiana tabacum]
          Length = 671

 Score =  909 bits (2349), Expect = 0.0
 Identities = 448/663 (67%), Positives = 537/663 (80%), Gaps = 4/663 (0%)
 Frame = -1

Query: 2079 CFVTRLGFSFSASGKTNSFESVPDLEKSMYTQIDGFPCVRLLNLSGEIGCSNPGRGNVVA 1900
            CF+ +   S SAS + NSF+SVPDLEKSMY  IDG+PCVRLLNLSGEIGCSNPGR N+VA
Sbjct: 12   CFIAQFCLSISASDQVNSFQSVPDLEKSMYMAIDGYPCVRLLNLSGEIGCSNPGRANIVA 71

Query: 1899 PIVRFKNANEFVGPAAILVSLDEFESLLSRVSNDPDFARKVAGILVESTTQVQNGIKGFS 1720
            P+ RFK AN+   P+A++VS+D+FE L  R+SND +F+R V G+LVES +Q+QNG+KGFS
Sbjct: 72   PVARFKTANKLAEPSALVVSIDQFEELFGRLSNDAEFSRHVVGVLVESGSQLQNGLKGFS 131

Query: 1719 PDVKFPQAGFAPYRSNNFEWNPAGSGIMWKAYNFPVFLLSKNSSSILQEVALMNEKTKKA 1540
            PD KFPQA FAPYRS +FEWNP GSG+MWKAYNFPVFLLS +S+S LQE+AL NEK KK+
Sbjct: 132  PDKKFPQAEFAPYRSGSFEWNPIGSGLMWKAYNFPVFLLSNSSTSALQEIALRNEKRKKS 191

Query: 1539 YTKVVSEFDLVMQTTKSGTHDSDSCLKEGTCLPLGGYSVWSALPPINISSPLKAKPVVLT 1360
            YT  V++F+LVMQTTKSGT DS+SCL+E TCLPLGGYSVWSALPP+ ISS  KAKPV+L 
Sbjct: 192  YTVDVADFNLVMQTTKSGTRDSESCLREQTCLPLGGYSVWSALPPMAISSSEKAKPVILV 251

Query: 1359 MTSMDSASFFRDKNLGAESPISGLIALLAVVDSLSRLGGLEELNKQLVFVVLTGEAWGYL 1180
            + SMD+ASFFRDK++GA+SPISGLI+LL VVD+LSR+ GL++L+KQLVF V TGEAWGYL
Sbjct: 252  VASMDAASFFRDKSIGADSPISGLISLLTVVDALSRVDGLKDLDKQLVFAVFTGEAWGYL 311

Query: 1179 GSRRFFLESDQQSDTMKGLDLAMIETVVEIGSVGKSYPQGTKTFFAHTAGATSSVNGTLN 1000
            GSRRF LE DQ SD + GLDLA+IETV+EIGSVGK + Q  KTFFAH+   T++ NGTL+
Sbjct: 312  GSRRFLLELDQHSDAVSGLDLALIETVLEIGSVGKGFAQDDKTFFAHSTSETAT-NGTLS 370

Query: 999  ALQHAQDSLITESIMVKTASTSNPGVPPSSLMTFLRKKPQISGLVLEDFDSAFSNEFYHS 820
            A+Q A  SL T+SI +  AS SNPG+PPSSLM+FL+K P+ SG+VLEDFD+AF+N+FYHS
Sbjct: 371  AIQDALGSLRTQSIKISRASKSNPGLPPSSLMSFLKKNPKTSGVVLEDFDTAFTNKFYHS 430

Query: 819  HLDDLS-NINSTSIVAAASLVARTLYILAGGK---DPSAINNIKINSSFVEELLGCLLDC 652
            HLDDL  NINS++IVAAAS+VAR+LYILA  K     SA+N I IN+S VEELLGCLL C
Sbjct: 431  HLDDLPVNINSSAIVAAASVVARSLYILASNKKEIKTSALNTININASLVEELLGCLLSC 490

Query: 651  EPGLSCGLVKHYISPSTTCPSHYVGVILGEPSSKPYPAYAGDISRFVWNFLADKTSIPSK 472
            EPGLSC LV  YI+PST+CPSHYVGV+LGEPSS+PYP   GD+ RFVWNFLADKT+IPSK
Sbjct: 491  EPGLSCELVNRYIAPSTSCPSHYVGVVLGEPSSQPYPGNVGDVPRFVWNFLADKTAIPSK 550

Query: 471  NLSSSCSKDCNGDNELCIREEADGKGVCVISTTRFVPAYSTRLKYDDESGSWTVLPSNSS 292
            NLSS+C K C+G  E+C++ E DGKGVCVISTTR++PAYSTRLKY  ES +W VLP NSS
Sbjct: 551  NLSSTCPKGCSGKGEMCVKAETDGKGVCVISTTRYIPAYSTRLKY--ESDTWEVLPHNSS 608

Query: 291  DIMGVEDPVWTESNWDVINVRVYTVQTAAYDHXXXXXXXXXXXXXXXXXXIARTVIRKAL 112
            DIMG  DPVWTESNW+ I +RVYTVQ   +D                   +A+  I KAL
Sbjct: 609  DIMGEADPVWTESNWETIKLRVYTVQDTRFDTWILLLGIAVTVLSYIITVMAKAFITKAL 668

Query: 111  KQD 103
            K+D
Sbjct: 669  KRD 671


>ref|XP_009626875.1| PREDICTED: nicastrin isoform X2 [Nicotiana tomentosiformis]
          Length = 670

 Score =  907 bits (2344), Expect = 0.0
 Identities = 449/662 (67%), Positives = 533/662 (80%), Gaps = 3/662 (0%)
 Frame = -1

Query: 2079 CFVTRLGFSFSASGKTNSFESVPDLEKSMYTQIDGFPCVRLLNLSGEIGCSNPGRGNVVA 1900
            CF+ +   S SAS + NSF+SVPDLEKSMY  IDG+PCVRLLNLSGEIGCSNPGR N+VA
Sbjct: 12   CFIAQFCLSISASDQVNSFQSVPDLEKSMYMAIDGYPCVRLLNLSGEIGCSNPGRANIVA 71

Query: 1899 PIVRFKNANEFVGPAAILVSLDEFESLLSRVSNDPDFARKVAGILVESTTQVQNGIKGFS 1720
            P+ RFK AN+ V P+A++VS+D+FE L  R+SND DF+R V GILVES +Q+QNG+KGFS
Sbjct: 72   PVARFKTANKLVEPSALMVSIDQFEELFGRLSNDADFSRHVVGILVESGSQLQNGLKGFS 131

Query: 1719 PDVKFPQAGFAPYRSNNFEWNPAGSGIMWKAYNFPVFLLSKNSSSILQEVALMNEKTKKA 1540
            PD KFPQA FAPYRS +FEWNP GSG+MWKAYNFPVFLLS +S+S LQE+AL NEK KK+
Sbjct: 132  PDKKFPQAEFAPYRSGSFEWNPTGSGLMWKAYNFPVFLLSNSSTSALQEIALRNEKRKKS 191

Query: 1539 YTKVVSEFDLVMQTTKSGTHDSDSCLKEGTCLPLGGYSVWSALPPINISSPLKAKPVVLT 1360
            YT  V++F+LVMQTTKSGT DS+SCL+E TCLPLGGYSVWSALPPI ISS  KAKPV+L 
Sbjct: 192  YTVDVADFNLVMQTTKSGTRDSESCLREQTCLPLGGYSVWSALPPIAISSSEKAKPVILI 251

Query: 1359 MTSMDSASFFRDKNLGAESPISGLIALLAVVDSLSRLGGLEELNKQLVFVVLTGEAWGYL 1180
            + SMD+ASFFRDK++GA+SPISGLI+LLAVVD+LSR  G++ L+KQLVF V TGEAWGYL
Sbjct: 252  VASMDTASFFRDKSIGADSPISGLISLLAVVDALSRADGVKGLDKQLVFAVFTGEAWGYL 311

Query: 1179 GSRRFFLESDQQSDTMKGLDLAMIETVVEIGSVGKSYPQGTKTFFAHTAGATSSVNGTLN 1000
            GSRRF LE DQ SD + GLDLA+IETV+EIGSVGK + Q  KTFFAH+   T++ NG L+
Sbjct: 312  GSRRFLLELDQHSDAVSGLDLALIETVLEIGSVGKGFAQDDKTFFAHSTSETAT-NGMLS 370

Query: 999  ALQHAQDSLITESIMVKTASTSNPGVPPSSLMTFLRKKPQISGLVLEDFDSAFSNEFYHS 820
            A+Q A  SL  +SI V  AS SNPG+PPSSLM+FL+K P+ SG+VLEDFD+AF+N+FYHS
Sbjct: 371  AIQDALGSLNNQSIKVSRASKSNPGLPPSSLMSFLKKNPKTSGVVLEDFDTAFTNKFYHS 430

Query: 819  HLDDLSNINSTSIVAAASLVARTLYILAGGK---DPSAINNIKINSSFVEELLGCLLDCE 649
            HLDDL NINS++IVAAAS+VAR+LYILA  K     SA+N I IN+S VEELLGCLL CE
Sbjct: 431  HLDDLLNINSSAIVAAASVVARSLYILASDKKEIKTSALNTININASLVEELLGCLLSCE 490

Query: 648  PGLSCGLVKHYISPSTTCPSHYVGVILGEPSSKPYPAYAGDISRFVWNFLADKTSIPSKN 469
            PGLSC LV  YI+PS +CPSHYVGV+LGEPSS+PYP   GD+ RFVWNFLADKT+IPSKN
Sbjct: 491  PGLSCELVNRYIAPSASCPSHYVGVVLGEPSSQPYPGNVGDVPRFVWNFLADKTAIPSKN 550

Query: 468  LSSSCSKDCNGDNELCIREEADGKGVCVISTTRFVPAYSTRLKYDDESGSWTVLPSNSSD 289
            +SS+C K C+G  E+C++ E DGKGVCVISTTR+VPAYSTRLKY  ES +W VLP NSSD
Sbjct: 551  MSSACPKGCSGTGEVCVKAETDGKGVCVISTTRYVPAYSTRLKY--ESDTWGVLPHNSSD 608

Query: 288  IMGVEDPVWTESNWDVINVRVYTVQTAAYDHXXXXXXXXXXXXXXXXXXIARTVIRKALK 109
             MG  DPVWTESNW+ I +RVYTVQ   +D                   +A+  I KALK
Sbjct: 609  TMGEADPVWTESNWETIKLRVYTVQDTRFDTWVLLLGITVTVLSYIITAMAKAFITKALK 668

Query: 108  QD 103
            +D
Sbjct: 669  RD 670


>ref|XP_016488669.1| PREDICTED: nicastrin-like isoform X2 [Nicotiana tabacum]
          Length = 670

 Score =  907 bits (2343), Expect = 0.0
 Identities = 448/662 (67%), Positives = 533/662 (80%), Gaps = 3/662 (0%)
 Frame = -1

Query: 2079 CFVTRLGFSFSASGKTNSFESVPDLEKSMYTQIDGFPCVRLLNLSGEIGCSNPGRGNVVA 1900
            CF+ +   S SAS + NSF+SVPDLEKSMY  IDG+PCVRLLNLSGEIGCSNPGR N+VA
Sbjct: 12   CFIAQFCLSISASDQVNSFQSVPDLEKSMYMAIDGYPCVRLLNLSGEIGCSNPGRANIVA 71

Query: 1899 PIVRFKNANEFVGPAAILVSLDEFESLLSRVSNDPDFARKVAGILVESTTQVQNGIKGFS 1720
            P+ RFK AN+ V P+A++VS+D+FE L  R+SND DF+R V G+LVES +Q+QNG+KGFS
Sbjct: 72   PVARFKTANKLVEPSALMVSIDQFEELFGRLSNDADFSRHVVGVLVESGSQLQNGLKGFS 131

Query: 1719 PDVKFPQAGFAPYRSNNFEWNPAGSGIMWKAYNFPVFLLSKNSSSILQEVALMNEKTKKA 1540
            PD KFPQA FAPYRS +FEWNP GSG+MWKAYNFPVFLLS +S+S LQE+AL NEK KK+
Sbjct: 132  PDKKFPQAEFAPYRSGSFEWNPTGSGLMWKAYNFPVFLLSNSSTSALQEIALRNEKRKKS 191

Query: 1539 YTKVVSEFDLVMQTTKSGTHDSDSCLKEGTCLPLGGYSVWSALPPINISSPLKAKPVVLT 1360
            YT  V++F+LVMQTTKSGT DS+SCL+E TCLPLGGYSVWSALPPI ISS  KAKPV+L 
Sbjct: 192  YTVDVADFNLVMQTTKSGTRDSESCLREQTCLPLGGYSVWSALPPIAISSSEKAKPVILI 251

Query: 1359 MTSMDSASFFRDKNLGAESPISGLIALLAVVDSLSRLGGLEELNKQLVFVVLTGEAWGYL 1180
            + SMD+ASFFRDK++GA+SPISGLI+LLAVVD+LSR  G++ L+KQLVF V TGEAWGYL
Sbjct: 252  VASMDTASFFRDKSIGADSPISGLISLLAVVDALSRADGVKGLDKQLVFAVFTGEAWGYL 311

Query: 1179 GSRRFFLESDQQSDTMKGLDLAMIETVVEIGSVGKSYPQGTKTFFAHTAGATSSVNGTLN 1000
            GSRRF LE DQ SD + GLDLA+IETV+EIGSVGK + Q  KTFFAH+   T++ NG L+
Sbjct: 312  GSRRFLLELDQHSDAVSGLDLALIETVLEIGSVGKGFAQDDKTFFAHSTSETAT-NGMLS 370

Query: 999  ALQHAQDSLITESIMVKTASTSNPGVPPSSLMTFLRKKPQISGLVLEDFDSAFSNEFYHS 820
            A+Q A  SL  +SI V  AS SNPG+PPSSLM+FL+K P+ SG+VLEDFD+AF+N+FYHS
Sbjct: 371  AIQDALGSLNNQSIKVSRASKSNPGLPPSSLMSFLKKNPKTSGVVLEDFDTAFTNKFYHS 430

Query: 819  HLDDLSNINSTSIVAAASLVARTLYILAGGK---DPSAINNIKINSSFVEELLGCLLDCE 649
            HLDDL NINS++IVAAAS+VAR+LYILA  K     SA+N I IN+S VEELLGCLL CE
Sbjct: 431  HLDDLLNINSSAIVAAASVVARSLYILASDKKEIKTSALNTININASLVEELLGCLLSCE 490

Query: 648  PGLSCGLVKHYISPSTTCPSHYVGVILGEPSSKPYPAYAGDISRFVWNFLADKTSIPSKN 469
            PGLSC LV  YI+PS +CPSHYVGV+LGEPSS+PYP   GD+ RFVWNFLADKT+IPSKN
Sbjct: 491  PGLSCELVNRYIAPSASCPSHYVGVVLGEPSSQPYPGNVGDVPRFVWNFLADKTAIPSKN 550

Query: 468  LSSSCSKDCNGDNELCIREEADGKGVCVISTTRFVPAYSTRLKYDDESGSWTVLPSNSSD 289
            +SS+C K C+G  E+C++ E DGKGVCVISTTR+VPAYSTRLKY  ES +W VLP NSSD
Sbjct: 551  MSSACPKGCSGTGEVCVKAETDGKGVCVISTTRYVPAYSTRLKY--ESDTWGVLPHNSSD 608

Query: 288  IMGVEDPVWTESNWDVINVRVYTVQTAAYDHXXXXXXXXXXXXXXXXXXIARTVIRKALK 109
             MG  DPVWTESNW+ I +RVYTVQ   +D                   +A+  I KALK
Sbjct: 609  TMGEADPVWTESNWETIKLRVYTVQDTRFDTWVLLLGITVTVLSYIITAMAKAFITKALK 668

Query: 108  QD 103
            +D
Sbjct: 669  RD 670


>ref|XP_019223513.1| PREDICTED: nicastrin isoform X1 [Nicotiana attenuata]
 gb|OIT34003.1| nicastrin [Nicotiana attenuata]
          Length = 671

 Score =  905 bits (2338), Expect = 0.0
 Identities = 445/663 (67%), Positives = 538/663 (81%), Gaps = 4/663 (0%)
 Frame = -1

Query: 2079 CFVTRLGFSFSASGKTNSFESVPDLEKSMYTQIDGFPCVRLLNLSGEIGCSNPGRGNVVA 1900
            CF+ +   S SAS + NSF+SVPDLEKSMY  IDG+PCVRLLNLSGEIGCSNPGR N+VA
Sbjct: 12   CFIAQFCLSISASDQVNSFQSVPDLEKSMYMAIDGYPCVRLLNLSGEIGCSNPGRANIVA 71

Query: 1899 PIVRFKNANEFVGPAAILVSLDEFESLLSRVSNDPDFARKVAGILVESTTQVQNGIKGFS 1720
            P+ RFK AN+   P+A++VS+++FE L  R+SND +F+R V G+LVES +Q+QNG+KGFS
Sbjct: 72   PVARFKTANKLAEPSALMVSIEQFEELFGRLSNDAEFSRHVVGVLVESGSQLQNGLKGFS 131

Query: 1719 PDVKFPQAGFAPYRSNNFEWNPAGSGIMWKAYNFPVFLLSKNSSSILQEVALMNEKTKKA 1540
            PD KFPQA FAPY+S +FEWNP GSG+MWKAYNFPVFLLS +S+S LQE+AL NEK KK+
Sbjct: 132  PDKKFPQAEFAPYQSGHFEWNPIGSGLMWKAYNFPVFLLSNSSTSALQEIALRNEKRKKS 191

Query: 1539 YTKVVSEFDLVMQTTKSGTHDSDSCLKEGTCLPLGGYSVWSALPPINISSPLKAKPVVLT 1360
            YT  V++F+LVMQTTKSGT DS+SCL+E TCLPLGGYSVWSALPP+ ISS  KAKPV+L 
Sbjct: 192  YTVDVADFNLVMQTTKSGTRDSESCLREQTCLPLGGYSVWSALPPMAISSSEKAKPVILV 251

Query: 1359 MTSMDSASFFRDKNLGAESPISGLIALLAVVDSLSRLGGLEELNKQLVFVVLTGEAWGYL 1180
            + SMD+ASFFRDK++GA+SPISGLI+LLAVVD+LSR+ GL++L+KQLVF V TGEAWGYL
Sbjct: 252  VASMDAASFFRDKSIGADSPISGLISLLAVVDALSRVDGLKDLDKQLVFAVFTGEAWGYL 311

Query: 1179 GSRRFFLESDQQSDTMKGLDLAMIETVVEIGSVGKSYPQGTKTFFAHTAGATSSVNGTLN 1000
            GSRRF LE DQ SD + GLDLA+IETV+EIGSVGK + +  KTFFAH+   T++ NGTL+
Sbjct: 312  GSRRFLLELDQHSDAVSGLDLALIETVLEIGSVGKGFARDDKTFFAHSTSETAT-NGTLS 370

Query: 999  ALQHAQDSLITESIMVKTASTSNPGVPPSSLMTFLRKKPQISGLVLEDFDSAFSNEFYHS 820
            A+Q A  SL T+S  +  AS SNPG+PPSSLM+FL+K P+ SG+VLEDFD+AF+N+FYHS
Sbjct: 371  AIQDAVGSLKTQSTKISRASKSNPGLPPSSLMSFLKKNPKTSGVVLEDFDTAFTNKFYHS 430

Query: 819  HLDDLS-NINSTSIVAAASLVARTLYILAGGK---DPSAINNIKINSSFVEELLGCLLDC 652
            HLDDL  NINS++IVAAAS+VAR+LYILA  K     SA+N I IN+S VEELLGCLL C
Sbjct: 431  HLDDLPVNINSSAIVAAASVVARSLYILASDKKEIKTSALNTININASLVEELLGCLLSC 490

Query: 651  EPGLSCGLVKHYISPSTTCPSHYVGVILGEPSSKPYPAYAGDISRFVWNFLADKTSIPSK 472
            EPGLSC LV  YI+PST+CPSHYVGV+LGEPSS+PYP   GD+ RFVWNFLADKT+IPSK
Sbjct: 491  EPGLSCELVNRYIAPSTSCPSHYVGVVLGEPSSQPYPGNVGDVPRFVWNFLADKTAIPSK 550

Query: 471  NLSSSCSKDCNGDNELCIREEADGKGVCVISTTRFVPAYSTRLKYDDESGSWTVLPSNSS 292
            NLSS+C K C+G+ E+C++ E DGKGVCVISTTR++PAYSTRLKY  ES +W VLP NSS
Sbjct: 551  NLSSTCPKGCSGNGEMCVKAETDGKGVCVISTTRYIPAYSTRLKY--ESDTWEVLPHNSS 608

Query: 291  DIMGVEDPVWTESNWDVINVRVYTVQTAAYDHXXXXXXXXXXXXXXXXXXIARTVIRKAL 112
            DIMG  DPVWTESNW+ I +RVYTVQ   +D                   +A+  I KAL
Sbjct: 609  DIMGEADPVWTESNWETIKLRVYTVQDTRFDTWILLLGIAVTVLSYIITVMAKAFITKAL 668

Query: 111  KQD 103
            K+D
Sbjct: 669  KRD 671


>ref|XP_009626874.1| PREDICTED: nicastrin isoform X1 [Nicotiana tomentosiformis]
          Length = 671

 Score =  903 bits (2333), Expect = 0.0
 Identities = 449/663 (67%), Positives = 533/663 (80%), Gaps = 4/663 (0%)
 Frame = -1

Query: 2079 CFVTRLGFSFSASGKTNSFESVPDLEKSMYTQIDGFPCVRLLNLSGEIGCSNPGRGNVVA 1900
            CF+ +   S SAS + NSF+SVPDLEKSMY  IDG+PCVRLLNLSGEIGCSNPGR N+VA
Sbjct: 12   CFIAQFCLSISASDQVNSFQSVPDLEKSMYMAIDGYPCVRLLNLSGEIGCSNPGRANIVA 71

Query: 1899 PIVRFKNANEFVGPAAILVSLDEFESLLSRVSNDPDFARKVAGILVESTTQVQNGIKGFS 1720
            P+ RFK AN+ V P+A++VS+D+FE L  R+SND DF+R V GILVES +Q+QNG+KGFS
Sbjct: 72   PVARFKTANKLVEPSALMVSIDQFEELFGRLSNDADFSRHVVGILVESGSQLQNGLKGFS 131

Query: 1719 PDVKFPQAGFAPYRSNNFEWNPAGSGIMWKAYNFPVFLLSKNSSSILQEVALMNEKTKKA 1540
            PD KFPQA FAPYRS +FEWNP GSG+MWKAYNFPVFLLS +S+S LQE+AL NEK KK+
Sbjct: 132  PDKKFPQAEFAPYRSGSFEWNPTGSGLMWKAYNFPVFLLSNSSTSALQEIALRNEKRKKS 191

Query: 1539 YTKVVSEFDLVMQTTKSGTHDSDSCLKEGTCLPLGGYSVWSALPPINISSPLKAKPVVLT 1360
            YT  V++F+LVMQTTKSGT DS+SCL+E TCLPLGGYSVWSALPPI ISS  KAKPV+L 
Sbjct: 192  YTVDVADFNLVMQTTKSGTRDSESCLREQTCLPLGGYSVWSALPPIAISSSEKAKPVILI 251

Query: 1359 MTSMDSASFFRDKNLGAESPISGLIALLAVVDSLSRLGGLEELNKQLVFVVLTGEAWGYL 1180
            + SMD+ASFFRDK++GA+SPISGLI+LLAVVD+LSR  G++ L+KQLVF V TGEAWGYL
Sbjct: 252  VASMDTASFFRDKSIGADSPISGLISLLAVVDALSRADGVKGLDKQLVFAVFTGEAWGYL 311

Query: 1179 GSRRFFLESDQQSDTMKGLDLAMIETVVEIGSVGKSYPQGTKTFFAHTAGATSSVNGTLN 1000
            GSRRF LE DQ SD + GLDLA+IETV+EIGSVGK + Q  KTFFAH+   T++ NG L+
Sbjct: 312  GSRRFLLELDQHSDAVSGLDLALIETVLEIGSVGKGFAQDDKTFFAHSTSETAT-NGMLS 370

Query: 999  ALQHAQDSLITESIMVKTASTSNPGVPPSSLMTFLRKKPQISGLVLEDFDSAFSNEFYHS 820
            A+Q A  SL  +SI V  AS SNPG+PPSSLM+FL+K P+ SG+VLEDFD+AF+N+FYHS
Sbjct: 371  AIQDALGSLNNQSIKVSRASKSNPGLPPSSLMSFLKKNPKTSGVVLEDFDTAFTNKFYHS 430

Query: 819  HLDDLS-NINSTSIVAAASLVARTLYILAGGK---DPSAINNIKINSSFVEELLGCLLDC 652
            HLDDL  NINS++IVAAAS+VAR+LYILA  K     SA+N I IN+S VEELLGCLL C
Sbjct: 431  HLDDLPVNINSSAIVAAASVVARSLYILASDKKEIKTSALNTININASLVEELLGCLLSC 490

Query: 651  EPGLSCGLVKHYISPSTTCPSHYVGVILGEPSSKPYPAYAGDISRFVWNFLADKTSIPSK 472
            EPGLSC LV  YI+PS +CPSHYVGV+LGEPSS+PYP   GD+ RFVWNFLADKT+IPSK
Sbjct: 491  EPGLSCELVNRYIAPSASCPSHYVGVVLGEPSSQPYPGNVGDVPRFVWNFLADKTAIPSK 550

Query: 471  NLSSSCSKDCNGDNELCIREEADGKGVCVISTTRFVPAYSTRLKYDDESGSWTVLPSNSS 292
            N+SS+C K C+G  E+C++ E DGKGVCVISTTR+VPAYSTRLKY  ES +W VLP NSS
Sbjct: 551  NMSSACPKGCSGTGEVCVKAETDGKGVCVISTTRYVPAYSTRLKY--ESDTWGVLPHNSS 608

Query: 291  DIMGVEDPVWTESNWDVINVRVYTVQTAAYDHXXXXXXXXXXXXXXXXXXIARTVIRKAL 112
            D MG  DPVWTESNW+ I +RVYTVQ   +D                   +A+  I KAL
Sbjct: 609  DTMGEADPVWTESNWETIKLRVYTVQDTRFDTWVLLLGITVTVLSYIITAMAKAFITKAL 668

Query: 111  KQD 103
            K+D
Sbjct: 669  KRD 671


>ref|XP_016488668.1| PREDICTED: nicastrin-like isoform X1 [Nicotiana tabacum]
          Length = 671

 Score =  902 bits (2332), Expect = 0.0
 Identities = 448/663 (67%), Positives = 533/663 (80%), Gaps = 4/663 (0%)
 Frame = -1

Query: 2079 CFVTRLGFSFSASGKTNSFESVPDLEKSMYTQIDGFPCVRLLNLSGEIGCSNPGRGNVVA 1900
            CF+ +   S SAS + NSF+SVPDLEKSMY  IDG+PCVRLLNLSGEIGCSNPGR N+VA
Sbjct: 12   CFIAQFCLSISASDQVNSFQSVPDLEKSMYMAIDGYPCVRLLNLSGEIGCSNPGRANIVA 71

Query: 1899 PIVRFKNANEFVGPAAILVSLDEFESLLSRVSNDPDFARKVAGILVESTTQVQNGIKGFS 1720
            P+ RFK AN+ V P+A++VS+D+FE L  R+SND DF+R V G+LVES +Q+QNG+KGFS
Sbjct: 72   PVARFKTANKLVEPSALMVSIDQFEELFGRLSNDADFSRHVVGVLVESGSQLQNGLKGFS 131

Query: 1719 PDVKFPQAGFAPYRSNNFEWNPAGSGIMWKAYNFPVFLLSKNSSSILQEVALMNEKTKKA 1540
            PD KFPQA FAPYRS +FEWNP GSG+MWKAYNFPVFLLS +S+S LQE+AL NEK KK+
Sbjct: 132  PDKKFPQAEFAPYRSGSFEWNPTGSGLMWKAYNFPVFLLSNSSTSALQEIALRNEKRKKS 191

Query: 1539 YTKVVSEFDLVMQTTKSGTHDSDSCLKEGTCLPLGGYSVWSALPPINISSPLKAKPVVLT 1360
            YT  V++F+LVMQTTKSGT DS+SCL+E TCLPLGGYSVWSALPPI ISS  KAKPV+L 
Sbjct: 192  YTVDVADFNLVMQTTKSGTRDSESCLREQTCLPLGGYSVWSALPPIAISSSEKAKPVILI 251

Query: 1359 MTSMDSASFFRDKNLGAESPISGLIALLAVVDSLSRLGGLEELNKQLVFVVLTGEAWGYL 1180
            + SMD+ASFFRDK++GA+SPISGLI+LLAVVD+LSR  G++ L+KQLVF V TGEAWGYL
Sbjct: 252  VASMDTASFFRDKSIGADSPISGLISLLAVVDALSRADGVKGLDKQLVFAVFTGEAWGYL 311

Query: 1179 GSRRFFLESDQQSDTMKGLDLAMIETVVEIGSVGKSYPQGTKTFFAHTAGATSSVNGTLN 1000
            GSRRF LE DQ SD + GLDLA+IETV+EIGSVGK + Q  KTFFAH+   T++ NG L+
Sbjct: 312  GSRRFLLELDQHSDAVSGLDLALIETVLEIGSVGKGFAQDDKTFFAHSTSETAT-NGMLS 370

Query: 999  ALQHAQDSLITESIMVKTASTSNPGVPPSSLMTFLRKKPQISGLVLEDFDSAFSNEFYHS 820
            A+Q A  SL  +SI V  AS SNPG+PPSSLM+FL+K P+ SG+VLEDFD+AF+N+FYHS
Sbjct: 371  AIQDALGSLNNQSIKVSRASKSNPGLPPSSLMSFLKKNPKTSGVVLEDFDTAFTNKFYHS 430

Query: 819  HLDDLS-NINSTSIVAAASLVARTLYILAGGK---DPSAINNIKINSSFVEELLGCLLDC 652
            HLDDL  NINS++IVAAAS+VAR+LYILA  K     SA+N I IN+S VEELLGCLL C
Sbjct: 431  HLDDLPVNINSSAIVAAASVVARSLYILASDKKEIKTSALNTININASLVEELLGCLLSC 490

Query: 651  EPGLSCGLVKHYISPSTTCPSHYVGVILGEPSSKPYPAYAGDISRFVWNFLADKTSIPSK 472
            EPGLSC LV  YI+PS +CPSHYVGV+LGEPSS+PYP   GD+ RFVWNFLADKT+IPSK
Sbjct: 491  EPGLSCELVNRYIAPSASCPSHYVGVVLGEPSSQPYPGNVGDVPRFVWNFLADKTAIPSK 550

Query: 471  NLSSSCSKDCNGDNELCIREEADGKGVCVISTTRFVPAYSTRLKYDDESGSWTVLPSNSS 292
            N+SS+C K C+G  E+C++ E DGKGVCVISTTR+VPAYSTRLKY  ES +W VLP NSS
Sbjct: 551  NMSSACPKGCSGTGEVCVKAETDGKGVCVISTTRYVPAYSTRLKY--ESDTWGVLPHNSS 608

Query: 291  DIMGVEDPVWTESNWDVINVRVYTVQTAAYDHXXXXXXXXXXXXXXXXXXIARTVIRKAL 112
            D MG  DPVWTESNW+ I +RVYTVQ   +D                   +A+  I KAL
Sbjct: 609  DTMGEADPVWTESNWETIKLRVYTVQDTRFDTWVLLLGITVTVLSYIITAMAKAFITKAL 668

Query: 111  KQD 103
            K+D
Sbjct: 669  KRD 671


>ref|XP_006352434.1| PREDICTED: nicastrin isoform X2 [Solanum tuberosum]
          Length = 670

 Score =  894 bits (2311), Expect = 0.0
 Identities = 443/662 (66%), Positives = 528/662 (79%), Gaps = 3/662 (0%)
 Frame = -1

Query: 2079 CFVTRLGFSFSASGKTNSFESVPDLEKSMYTQIDGFPCVRLLNLSGEIGCSNPGRGNVVA 1900
            C + +   SFSAS +  SFESVPDLEKSMY  IDG+PCVRLLNLSGEIGCSNPGR N+VA
Sbjct: 12   CLLAQFFLSFSASDQVKSFESVPDLEKSMYMAIDGYPCVRLLNLSGEIGCSNPGRANIVA 71

Query: 1899 PIVRFKNANEFVGPAAILVSLDEFESLLSRVSNDPDFARKVAGILVESTTQVQNGIKGFS 1720
            P+ RFK  N+   P+A+LVS+D+FE L +R+S D DF+R V G+LVES++Q+QNG+KGFS
Sbjct: 72   PVTRFKTENKLAEPSALLVSMDQFEDLFARLSIDADFSRHVVGVLVESSSQLQNGLKGFS 131

Query: 1719 PDVKFPQAGFAPYRSNNFEWNPAGSGIMWKAYNFPVFLLSKNSSSILQEVALMNEKTKKA 1540
            PD KFPQA F PY+S  FEWNP GSG+MWKAYNFPVFLLS +S+  LQEVAL NEK KK+
Sbjct: 132  PDKKFPQAEFTPYQSGKFEWNPTGSGLMWKAYNFPVFLLSNSSTLALQEVALRNEKRKKS 191

Query: 1539 YTKVVSEFDLVMQTTKSGTHDSDSCLKEGTCLPLGGYSVWSALPPINISSPLKAKPVVLT 1360
             T  V++FDLVMQTTKSGT DS+SCL+E TCLPLGGYSVWSALPPI +SS  KAKPV+LT
Sbjct: 192  STVDVADFDLVMQTTKSGTRDSESCLREQTCLPLGGYSVWSALPPIIVSSSKKAKPVILT 251

Query: 1359 MTSMDSASFFRDKNLGAESPISGLIALLAVVDSLSRLGGLEELNKQLVFVVLTGEAWGYL 1180
            + SMD+AS FRD ++GA+SPISGLI+LLAVVD+LSR+ GL +L+KQLVF V TGEAWGYL
Sbjct: 252  VASMDAASLFRDVSIGADSPISGLISLLAVVDALSRVDGLGDLDKQLVFAVFTGEAWGYL 311

Query: 1179 GSRRFFLESDQQSDTMKGLDLAMIETVVEIGSVGKSYPQGTKTFFAHTAGATSSVNGTLN 1000
            GSRRF LE DQ SD + GLDLA+IETV+EIGSVGK + Q   TFFAH+    S+ NGTL+
Sbjct: 312  GSRRFLLELDQHSDAVSGLDLALIETVLEIGSVGKGFTQDDNTFFAHST-TESATNGTLS 370

Query: 999  ALQHAQDSLITESIMVKTASTSNPGVPPSSLMTFLRKKPQISGLVLEDFDSAFSNEFYHS 820
            AL+ A  SL T+SI +  AS SNPG+PPSSLM+FL+K P+ SG+VLEDFD+AF+N+FYHS
Sbjct: 371  ALKDALGSLKTQSIKISRASKSNPGLPPSSLMSFLKKNPETSGVVLEDFDAAFTNKFYHS 430

Query: 819  HLDDLSNINSTSIVAAASLVARTLYILAGGKDP---SAINNIKINSSFVEELLGCLLDCE 649
            HLDDLSNINS++IVAAAS+VAR+LYILA  K     S +N I IN+S VEELLGCLL CE
Sbjct: 431  HLDDLSNINSSAIVAAASIVARSLYILASDKKEIKNSVLNTININASLVEELLGCLLSCE 490

Query: 648  PGLSCGLVKHYISPSTTCPSHYVGVILGEPSSKPYPAYAGDISRFVWNFLADKTSIPSKN 469
            PG +C LV HYI+PST CPSHYVGV++GEPSS+PY    GD+SRFVWNFLADKT+IPSKN
Sbjct: 491  PGYTCELVNHYIAPSTRCPSHYVGVVMGEPSSQPYLGNVGDVSRFVWNFLADKTAIPSKN 550

Query: 468  LSSSCSKDCNGDNELCIREEADGKGVCVISTTRFVPAYSTRLKYDDESGSWTVLPSNSSD 289
            +SS+C K C+G+ E+C++ E DGKGVCVISTTR+VPAYSTRLKY  ES +W VLP NSSD
Sbjct: 551  MSSTCPKGCSGNGEMCVKAETDGKGVCVISTTRYVPAYSTRLKY--ESETWEVLPHNSSD 608

Query: 288  IMGVEDPVWTESNWDVINVRVYTVQTAAYDHXXXXXXXXXXXXXXXXXXIARTVIRKALK 109
             MG  DPVWTESNWD I +RVYTVQ   +D                   I++  I KALK
Sbjct: 609  TMGEADPVWTESNWDTIRLRVYTVQDTGFDLLVLLLGITVTVLSYIIIVISKAFITKALK 668

Query: 108  QD 103
            +D
Sbjct: 669  RD 670


>ref|XP_006352433.1| PREDICTED: nicastrin isoform X1 [Solanum tuberosum]
          Length = 671

 Score =  890 bits (2299), Expect = 0.0
 Identities = 443/663 (66%), Positives = 528/663 (79%), Gaps = 4/663 (0%)
 Frame = -1

Query: 2079 CFVTRLGFSFSASGKTNSFESVPDLEKSMYTQIDGFPCVRLLNLSGEIGCSNPGRGNVVA 1900
            C + +   SFSAS +  SFESVPDLEKSMY  IDG+PCVRLLNLSGEIGCSNPGR N+VA
Sbjct: 12   CLLAQFFLSFSASDQVKSFESVPDLEKSMYMAIDGYPCVRLLNLSGEIGCSNPGRANIVA 71

Query: 1899 PIVRFKNANEFVGPAAILVSLDEFESLLSRVSNDPDFARKVAGILVESTTQVQNGIKGFS 1720
            P+ RFK  N+   P+A+LVS+D+FE L +R+S D DF+R V G+LVES++Q+QNG+KGFS
Sbjct: 72   PVTRFKTENKLAEPSALLVSMDQFEDLFARLSIDADFSRHVVGVLVESSSQLQNGLKGFS 131

Query: 1719 PDVKFPQAGFAPYRSNNFEWNPAGSGIMWKAYNFPVFLLSKNSSSILQEVALMNEKTKKA 1540
            PD KFPQA F PY+S  FEWNP GSG+MWKAYNFPVFLLS +S+  LQEVAL NEK KK+
Sbjct: 132  PDKKFPQAEFTPYQSGKFEWNPTGSGLMWKAYNFPVFLLSNSSTLALQEVALRNEKRKKS 191

Query: 1539 YTKVVSEFDLVMQTTKSGTHDSDSCLKEGTCLPLGGYSVWSALPPINISSPLKAKPVVLT 1360
             T  V++FDLVMQTTKSGT DS+SCL+E TCLPLGGYSVWSALPPI +SS  KAKPV+LT
Sbjct: 192  STVDVADFDLVMQTTKSGTRDSESCLREQTCLPLGGYSVWSALPPIIVSSSKKAKPVILT 251

Query: 1359 MTSMDSASFFRDKNLGAESPISGLIALLAVVDSLSRLGGLEELNKQLVFVVLTGEAWGYL 1180
            + SMD+AS FRD ++GA+SPISGLI+LLAVVD+LSR+ GL +L+KQLVF V TGEAWGYL
Sbjct: 252  VASMDAASLFRDVSIGADSPISGLISLLAVVDALSRVDGLGDLDKQLVFAVFTGEAWGYL 311

Query: 1179 GSRRFFLESDQQSDTMKGLDLAMIETVVEIGSVGKSYPQGTKTFFAHTAGATSSVNGTLN 1000
            GSRRF LE DQ SD + GLDLA+IETV+EIGSVGK + Q   TFFAH+    S+ NGTL+
Sbjct: 312  GSRRFLLELDQHSDAVSGLDLALIETVLEIGSVGKGFTQDDNTFFAHST-TESATNGTLS 370

Query: 999  ALQHAQDSLITESIMVKTASTSNPGVPPSSLMTFLRKKPQISGLVLEDFDSAFSNEFYHS 820
            AL+ A  SL T+SI +  AS SNPG+PPSSLM+FL+K P+ SG+VLEDFD+AF+N+FYHS
Sbjct: 371  ALKDALGSLKTQSIKISRASKSNPGLPPSSLMSFLKKNPETSGVVLEDFDAAFTNKFYHS 430

Query: 819  HLDDLS-NINSTSIVAAASLVARTLYILAGGKDP---SAINNIKINSSFVEELLGCLLDC 652
            HLDDLS NINS++IVAAAS+VAR+LYILA  K     S +N I IN+S VEELLGCLL C
Sbjct: 431  HLDDLSANINSSAIVAAASIVARSLYILASDKKEIKNSVLNTININASLVEELLGCLLSC 490

Query: 651  EPGLSCGLVKHYISPSTTCPSHYVGVILGEPSSKPYPAYAGDISRFVWNFLADKTSIPSK 472
            EPG +C LV HYI+PST CPSHYVGV++GEPSS+PY    GD+SRFVWNFLADKT+IPSK
Sbjct: 491  EPGYTCELVNHYIAPSTRCPSHYVGVVMGEPSSQPYLGNVGDVSRFVWNFLADKTAIPSK 550

Query: 471  NLSSSCSKDCNGDNELCIREEADGKGVCVISTTRFVPAYSTRLKYDDESGSWTVLPSNSS 292
            N+SS+C K C+G+ E+C++ E DGKGVCVISTTR+VPAYSTRLKY  ES +W VLP NSS
Sbjct: 551  NMSSTCPKGCSGNGEMCVKAETDGKGVCVISTTRYVPAYSTRLKY--ESETWEVLPHNSS 608

Query: 291  DIMGVEDPVWTESNWDVINVRVYTVQTAAYDHXXXXXXXXXXXXXXXXXXIARTVIRKAL 112
            D MG  DPVWTESNWD I +RVYTVQ   +D                   I++  I KAL
Sbjct: 609  DTMGEADPVWTESNWDTIRLRVYTVQDTGFDLLVLLLGITVTVLSYIIIVISKAFITKAL 668

Query: 111  KQD 103
            K+D
Sbjct: 669  KRD 671


>ref|XP_016551191.1| PREDICTED: nicastrin isoform X2 [Capsicum annuum]
          Length = 670

 Score =  888 bits (2295), Expect = 0.0
 Identities = 440/662 (66%), Positives = 527/662 (79%), Gaps = 3/662 (0%)
 Frame = -1

Query: 2079 CFVTRLGFSFSASGKTNSFESVPDLEKSMYTQIDGFPCVRLLNLSGEIGCSNPGRGNVVA 1900
            C + +  FSFS S + NSF+SVPDLEKSMY  IDG+PCVRLLNLSGEIGCSNPGR N+VA
Sbjct: 12   CLIAQFCFSFSVSDQVNSFQSVPDLEKSMYIAIDGYPCVRLLNLSGEIGCSNPGRANIVA 71

Query: 1899 PIVRFKNANEFVGPAAILVSLDEFESLLSRVSNDPDFARKVAGILVESTTQVQNGIKGFS 1720
            P+ RFK AN+   P+A+LVS+D+FE L +R+SND DF+  V G+LVES +Q+QN +KGFS
Sbjct: 72   PVARFKIANKLAEPSALLVSMDQFEDLFARLSNDADFSMHVVGVLVESGSQLQNSLKGFS 131

Query: 1719 PDVKFPQAGFAPYRSNNFEWNPAGSGIMWKAYNFPVFLLSKNSSSILQEVALMNEKTKKA 1540
            PD KFPQA FA Y+S NFEWNP GSG+MWKAYNFPVFLLS +S+  LQEVAL NEK  K+
Sbjct: 132  PDRKFPQAEFASYKSGNFEWNPTGSGLMWKAYNFPVFLLSNSSTLALQEVALRNEKRTKS 191

Query: 1539 YTKVVSEFDLVMQTTKSGTHDSDSCLKEGTCLPLGGYSVWSALPPINISSPLKAKPVVLT 1360
            YT  V++FDLVMQTTKSGT DS+SCL+E TCLPLGGYSVWSALPPI  SS  KAKP +LT
Sbjct: 192  YTVDVADFDLVMQTTKSGTRDSESCLREQTCLPLGGYSVWSALPPIITSSSKKAKPTILT 251

Query: 1359 MTSMDSASFFRDKNLGAESPISGLIALLAVVDSLSRLGGLEELNKQLVFVVLTGEAWGYL 1180
            + SMD+ SFFRDK++GA+SPISGLI+LLAVVDSLSR+ GL +L+KQLVF V TGEAWGYL
Sbjct: 252  VASMDATSFFRDKSVGADSPISGLISLLAVVDSLSRVDGLGDLDKQLVFAVFTGEAWGYL 311

Query: 1179 GSRRFFLESDQQSDTMKGLDLAMIETVVEIGSVGKSYPQGTKTFFAHTAGATSSVNGTLN 1000
            GSRRF LE DQ SD + GLDLA+IE V+EIGSVGK       TFFAH+    S+ +GTLN
Sbjct: 312  GSRRFLLELDQHSDAVSGLDLALIEKVLEIGSVGKGSAPDDNTFFAHST-RESATSGTLN 370

Query: 999  ALQHAQDSLITESIMVKTASTSNPGVPPSSLMTFLRKKPQISGLVLEDFDSAFSNEFYHS 820
            AL+ A  SL T+SI +  AS SNPG+PPSSLMTFL+K P+ SG+VLEDFD+ F+N+FYHS
Sbjct: 371  ALKDALGSLKTQSIKISRASKSNPGLPPSSLMTFLKKNPETSGVVLEDFDAVFTNKFYHS 430

Query: 819  HLDDLSNINSTSIVAAASLVARTLYILAGGK---DPSAINNIKINSSFVEELLGCLLDCE 649
            HLDDLSNINS++IVAAAS+VAR+LYILA  K     S +N+I IN+S VEEL+ CLL CE
Sbjct: 431  HLDDLSNINSSAIVAAASVVARSLYILASDKKEISNSVLNSININASLVEELVSCLLSCE 490

Query: 648  PGLSCGLVKHYISPSTTCPSHYVGVILGEPSSKPYPAYAGDISRFVWNFLADKTSIPSKN 469
            PGL+C LV  YI+PST+CP++YVGV+LGEPSS+PY    GD+SRFVWNFLADKT+IPSK+
Sbjct: 491  PGLTCELVNRYIAPSTSCPNNYVGVVLGEPSSQPYLGNVGDVSRFVWNFLADKTAIPSKD 550

Query: 468  LSSSCSKDCNGDNELCIREEADGKGVCVISTTRFVPAYSTRLKYDDESGSWTVLPSNSSD 289
            +SS+C K C+G+ E+C++ E DGKGVCVISTTR+VPAYSTRLKYD +  +W VLP NSSD
Sbjct: 551  VSSACPKGCSGNGEMCVKAETDGKGVCVISTTRYVPAYSTRLKYDTD--TWEVLPHNSSD 608

Query: 288  IMGVEDPVWTESNWDVINVRVYTVQTAAYDHXXXXXXXXXXXXXXXXXXIARTVIRKALK 109
             MG  DPVWTESNWD I +RVYTVQ + YDH                  I++  I KALK
Sbjct: 609  TMGEADPVWTESNWDTIRLRVYTVQDSRYDHLILLLGITITLLSYIIIVISKAFITKALK 668

Query: 108  QD 103
            +D
Sbjct: 669  RD 670


>ref|XP_004250204.1| PREDICTED: nicastrin isoform X2 [Solanum lycopersicum]
          Length = 670

 Score =  885 bits (2288), Expect = 0.0
 Identities = 438/662 (66%), Positives = 529/662 (79%), Gaps = 3/662 (0%)
 Frame = -1

Query: 2079 CFVTRLGFSFSASGKTNSFESVPDLEKSMYTQIDGFPCVRLLNLSGEIGCSNPGRGNVVA 1900
            C + +   SFSAS + NSFESVPDLEKSMY  IDG+PCVRLLNLSGEIGCSNPGR N+VA
Sbjct: 12   CLLAQFFLSFSASDQVNSFESVPDLEKSMYMAIDGYPCVRLLNLSGEIGCSNPGRANIVA 71

Query: 1899 PIVRFKNANEFVGPAAILVSLDEFESLLSRVSNDPDFARKVAGILVESTTQVQNGIKGFS 1720
            P+ RFK  N+   P+A+L+S+D+FE L +R+S D DF+R V G+LVES +Q+QNG+KGFS
Sbjct: 72   PVTRFKTENKLAEPSALLLSMDQFEDLFARLSIDADFSRHVVGVLVESGSQLQNGLKGFS 131

Query: 1719 PDVKFPQAGFAPYRSNNFEWNPAGSGIMWKAYNFPVFLLSKNSSSILQEVALMNEKTKKA 1540
            PD KFPQA FAPY+S  FEWNP G+G+MWKAYNFPVFLLS +S+  LQE+AL NEK KK+
Sbjct: 132  PDKKFPQAEFAPYQSGKFEWNPTGTGLMWKAYNFPVFLLSNSSTLALQEIALRNEKRKKS 191

Query: 1539 YTKVVSEFDLVMQTTKSGTHDSDSCLKEGTCLPLGGYSVWSALPPINISSPLKAKPVVLT 1360
             T  V++FDLVMQTTK+GT DS+SCL+E TCLPLGGYSVWSALPPIN SS  KAKP++LT
Sbjct: 192  STVDVADFDLVMQTTKTGTRDSESCLREQTCLPLGGYSVWSALPPINTSSSKKAKPMILT 251

Query: 1359 MTSMDSASFFRDKNLGAESPISGLIALLAVVDSLSRLGGLEELNKQLVFVVLTGEAWGYL 1180
            + SMD+ASFFRD ++GA+SPISGLI+LLAVVD+LSR+ GL +L+KQLVF V TGEAWGYL
Sbjct: 252  VASMDAASFFRDVSIGADSPISGLISLLAVVDALSRVDGLGDLDKQLVFAVFTGEAWGYL 311

Query: 1179 GSRRFFLESDQQSDTMKGLDLAMIETVVEIGSVGKSYPQGTKTFFAHTAGATSSVNGTLN 1000
            GSRRF LE DQ SD + GLDLA+IETV+EIGSVGK + Q   TFFAH+    S+ NGT +
Sbjct: 312  GSRRFILELDQHSDAVSGLDLALIETVLEIGSVGKGFTQDDNTFFAHST-MESATNGTFS 370

Query: 999  ALQHAQDSLITESIMVKTASTSNPGVPPSSLMTFLRKKPQISGLVLEDFDSAFSNEFYHS 820
            AL+ A  SL T+SI +  AS SNPG+PPSSLM+FL+K P+ SG+VLEDFD+AF+N+FYHS
Sbjct: 371  ALKDALGSLKTQSIKISRASKSNPGLPPSSLMSFLKKNPETSGVVLEDFDAAFTNKFYHS 430

Query: 819  HLDDLSNINSTSIVAAASLVARTLYILAGGKDP---SAINNIKINSSFVEELLGCLLDCE 649
            HLDDLSNINS++IVAAAS+VAR+LYILA  K     S +N I IN+S VEELLGCLL CE
Sbjct: 431  HLDDLSNINSSAIVAAASIVARSLYILASDKKEIKNSVLNTININASLVEELLGCLLSCE 490

Query: 648  PGLSCGLVKHYISPSTTCPSHYVGVILGEPSSKPYPAYAGDISRFVWNFLADKTSIPSKN 469
            PGL+C LV  YI+ ST+CPSHYVGV++GEPSS+PY    GD+SRFVWNFLADKT+IPSKN
Sbjct: 491  PGLTCELVNRYIASSTSCPSHYVGVVMGEPSSQPYLGNVGDVSRFVWNFLADKTAIPSKN 550

Query: 468  LSSSCSKDCNGDNELCIREEADGKGVCVISTTRFVPAYSTRLKYDDESGSWTVLPSNSSD 289
            +SS+C K C+G+ E+C++ E DGKGVCVISTTR+VPAYSTRLKY+ E  +W VLP NSSD
Sbjct: 551  MSSTCPKGCSGNGEMCVKVETDGKGVCVISTTRYVPAYSTRLKYEYE--TWEVLPHNSSD 608

Query: 288  IMGVEDPVWTESNWDVINVRVYTVQTAAYDHXXXXXXXXXXXXXXXXXXIARTVIRKALK 109
             M   DPVWTESNWD I +RVYTVQ + +D                   I++  I KALK
Sbjct: 609  TMEEADPVWTESNWDRIRLRVYTVQDSGFDLLVLLLGITVTVLSYIVIVISKAFITKALK 668

Query: 108  QD 103
            +D
Sbjct: 669  RD 670


>ref|XP_015058798.1| PREDICTED: nicastrin isoform X2 [Solanum pennellii]
          Length = 670

 Score =  885 bits (2287), Expect = 0.0
 Identities = 438/662 (66%), Positives = 528/662 (79%), Gaps = 3/662 (0%)
 Frame = -1

Query: 2079 CFVTRLGFSFSASGKTNSFESVPDLEKSMYTQIDGFPCVRLLNLSGEIGCSNPGRGNVVA 1900
            C + +   SFSAS + NSFESVPDLEKSMY  IDG+PCVRLLNLSGEIGCSNPGR N+VA
Sbjct: 12   CLLAQFFLSFSASDQVNSFESVPDLEKSMYMAIDGYPCVRLLNLSGEIGCSNPGRANIVA 71

Query: 1899 PIVRFKNANEFVGPAAILVSLDEFESLLSRVSNDPDFARKVAGILVESTTQVQNGIKGFS 1720
            P+ RFK  N+   P+A+LVS+D+FE L +R+S D DF+R V G+LVES +Q+QNG+KGFS
Sbjct: 72   PVTRFKTENKLAEPSALLVSMDQFEDLFARLSIDADFSRHVVGVLVESGSQLQNGLKGFS 131

Query: 1719 PDVKFPQAGFAPYRSNNFEWNPAGSGIMWKAYNFPVFLLSKNSSSILQEVALMNEKTKKA 1540
            PD KFPQA FAPY+S  FEWNP G+G+MWKAYNFPVFLLS +S+  LQE+AL NEK KK+
Sbjct: 132  PDKKFPQAEFAPYQSGKFEWNPTGTGLMWKAYNFPVFLLSNSSTLALQEIALRNEKRKKS 191

Query: 1539 YTKVVSEFDLVMQTTKSGTHDSDSCLKEGTCLPLGGYSVWSALPPINISSPLKAKPVVLT 1360
             T  V++FDLVMQTTK+GT DS+SCL+E TCLPLGGYSVWSALPPIN SS  KAKP++LT
Sbjct: 192  STVDVADFDLVMQTTKTGTRDSESCLREQTCLPLGGYSVWSALPPINTSSSKKAKPMILT 251

Query: 1359 MTSMDSASFFRDKNLGAESPISGLIALLAVVDSLSRLGGLEELNKQLVFVVLTGEAWGYL 1180
            + SMD+ASFFRD ++GA+SPISGLI+LLAVVD+LSR+ GL +L+KQLVF V TGEAWGYL
Sbjct: 252  VASMDAASFFRDVSIGADSPISGLISLLAVVDALSRVDGLGDLDKQLVFAVFTGEAWGYL 311

Query: 1179 GSRRFFLESDQQSDTMKGLDLAMIETVVEIGSVGKSYPQGTKTFFAHTAGATSSVNGTLN 1000
            GSRRF LE DQ SD + GLDLA+IETV+EIGSVGK + Q   TFFAH+    S+ NGT +
Sbjct: 312  GSRRFILELDQHSDAVSGLDLALIETVLEIGSVGKGFTQDDNTFFAHST-TESATNGTFS 370

Query: 999  ALQHAQDSLITESIMVKTASTSNPGVPPSSLMTFLRKKPQISGLVLEDFDSAFSNEFYHS 820
            AL+ A  SL T SI +  AS SNPG+PPSSLM+FL+K P+ SG+VLEDFD+AF+N+FYHS
Sbjct: 371  ALKDALGSLKTRSIKISRASKSNPGLPPSSLMSFLKKNPETSGVVLEDFDAAFTNKFYHS 430

Query: 819  HLDDLSNINSTSIVAAASLVARTLYILAGGKDP---SAINNIKINSSFVEELLGCLLDCE 649
            HLDDLSNINS++IVAAAS+VAR+LYILA  K     S +N I IN+S VEELLGCLL CE
Sbjct: 431  HLDDLSNINSSAIVAAASIVARSLYILASDKKEIKNSVLNTININASLVEELLGCLLSCE 490

Query: 648  PGLSCGLVKHYISPSTTCPSHYVGVILGEPSSKPYPAYAGDISRFVWNFLADKTSIPSKN 469
            PGL+C LV  YI+ ST+CPSHYVGV++GEPSS+PY    GD+SRFVWNFLADKT+IPS+N
Sbjct: 491  PGLTCELVNRYIASSTSCPSHYVGVVMGEPSSQPYLGNVGDVSRFVWNFLADKTAIPSQN 550

Query: 468  LSSSCSKDCNGDNELCIREEADGKGVCVISTTRFVPAYSTRLKYDDESGSWTVLPSNSSD 289
            +SS+C K C+G+ E+C++ E DGKGVCVISTTR+VPAYSTRLKY+ E  +W VLP NSSD
Sbjct: 551  MSSTCPKGCSGNGEMCVKAETDGKGVCVISTTRYVPAYSTRLKYEYE--TWEVLPHNSSD 608

Query: 288  IMGVEDPVWTESNWDVINVRVYTVQTAAYDHXXXXXXXXXXXXXXXXXXIARTVIRKALK 109
             M   DPVWTESNWD I +RVYTVQ + +D                   I++  I KALK
Sbjct: 609  TMEEADPVWTESNWDRIRLRVYTVQDSGFDLLVLLLGITVTVLSYIIIVISKAFITKALK 668

Query: 108  QD 103
            +D
Sbjct: 669  RD 670


>ref|XP_002264144.1| PREDICTED: nicastrin [Vitis vinifera]
 emb|CBI33472.3| unnamed protein product, partial [Vitis vinifera]
          Length = 671

 Score =  884 bits (2284), Expect = 0.0
 Identities = 443/661 (67%), Positives = 523/661 (79%), Gaps = 3/661 (0%)
 Frame = -1

Query: 2076 FVTRLGFSFSASGKTNSFESVPDLEKSMYTQIDGFPCVRLLNLSGEIGCSNPGRGNVVAP 1897
            FV +L     A     S ESVPDLEKSMY  +DG+PCVRLLNLSGEIGCSNPGR  VVAP
Sbjct: 13   FVAQLHPPLLAEEAMRSLESVPDLEKSMYMVVDGYPCVRLLNLSGEIGCSNPGREKVVAP 72

Query: 1896 IVRFKNANEFVGPAAILVSLDEFESLLSRVSNDPDFARKVAGILVESTTQVQNGIKGFSP 1717
            IVRFKN N     +AILVSLDE +S  +R+S+D +FAR V G+LVES +  QN +KGFSP
Sbjct: 73   IVRFKNVNVLAQSSAILVSLDEIQSFFTRLSHDSNFARNVGGVLVESVSASQNKLKGFSP 132

Query: 1716 DVKFPQAGFAPYRSNNFEWNPAGSGIMWKAYNFPVFLLSKNSSSILQEVALMNEKTKKAY 1537
              KFPQA FAPY+S N+EWNP GSGIMW  YNFP+FLLS++S+  LQEVA+ NEK KKAY
Sbjct: 133  VEKFPQAEFAPYQSINYEWNPIGSGIMWNTYNFPMFLLSQSSTLTLQEVAIKNEKNKKAY 192

Query: 1536 TKVVSEFDLVMQTTKSGTHDSDSCLKEGTCLPLGGYSVWSALPPINISSPLKAKPVVLTM 1357
            T  V+EFDLVMQTTKSGTHDS+SCLKE TCLPLGGYSVWS+LPPIN+SS  ++KPV+LT+
Sbjct: 193  TADVAEFDLVMQTTKSGTHDSESCLKEETCLPLGGYSVWSSLPPINVSSSDQSKPVILTV 252

Query: 1356 TSMDSASFFRDKNLGAESPISGLIALLAVVDSLSRLGGLEELNKQLVFVVLTGEAWGYLG 1177
             SMDSASFFRDK+LGA+SPISGLI+L+A VD+LS L GL +L+KQLVF+V TGEAWGYLG
Sbjct: 253  ASMDSASFFRDKSLGADSPISGLISLMAAVDALSHLDGLNDLSKQLVFLVFTGEAWGYLG 312

Query: 1176 SRRFFLESDQQSDTMKGLDLAMIETVVEIGSVGKSYPQGTKTFFAHTAGATSSVNGTLNA 997
            SRRF LE D  SD +KG+D  +IE V+EIGSVGK + QG KTFFAH A  +S  N TLNA
Sbjct: 313  SRRFLLELDLHSDFVKGIDSTLIEMVMEIGSVGKGFSQGVKTFFAHVAEVSSVTNETLNA 372

Query: 996  LQHAQDSLITESIMVKTASTSNPGVPPSSLMTFLRKKPQISGLVLEDFDSAFSNEFYHSH 817
            LQ A+DSL +ESIM+ TA++SNPG+PPSSLM+FLRK    SG+VLEDFD+ F+N+FYHSH
Sbjct: 373  LQQAKDSLKSESIMISTANSSNPGIPPSSLMSFLRKNSSTSGIVLEDFDATFANQFYHSH 432

Query: 816  LDDLSNINSTSIVAAASLVARTLYILAG-GKD--PSAINNIKINSSFVEELLGCLLDCEP 646
            LDDLSN+NS++IVAAASLVARTLYILA   KD   SA++ I +N+S VE LLGCLL+C+P
Sbjct: 433  LDDLSNVNSSAIVAAASLVARTLYILASDDKDLSTSALSAINVNASLVEALLGCLLNCDP 492

Query: 645  GLSCGLVKHYISPSTTCPSHYVGVILGEPSSKPYPAYAGDISRFVWNFLADKTSIPSKNL 466
            GLSC LVK YI+P T CPS+YVGV+LGEPS+  YP Y  D+SRF+WNFLAD+TSIP +N 
Sbjct: 493  GLSCDLVKKYIAPRTNCPSNYVGVLLGEPSATLYPGYVSDVSRFIWNFLADRTSIPRENA 552

Query: 465  SSSCSKDCNGDNELCIREEADGKGVCVISTTRFVPAYSTRLKYDDESGSWTVLPSNSSDI 286
            +S+C KDC+ + E+CI EE DGKGVCVISTTR+VPAYSTRL +  ESG W V+P NSS+ 
Sbjct: 553  TSACPKDCSNEGEVCIGEELDGKGVCVISTTRYVPAYSTRLMF--ESGIWKVMPLNSSNS 610

Query: 285  MGVEDPVWTESNWDVINVRVYTVQTAAYDHXXXXXXXXXXXXXXXXXXIARTVIRKALKQ 106
            MG EDPVWTESNWD I +RVYTVQ AAYD                   +AR  I KALKQ
Sbjct: 611  MGTEDPVWTESNWDAIGLRVYTVQNAAYDRLVLLAGLVVTVLAYLAIVVARAFITKALKQ 670

Query: 105  D 103
            D
Sbjct: 671  D 671