BLASTX 2.2.26 [Sep-21-2011]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= Rehmannia28_contig00007431
         (3690 letters)

Database: ./nr 
           84,704,028 sequences; 31,038,470,784 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

ref|XP_011093631.1| PREDICTED: DNA topoisomerase 1-like [Sesamum...  1427   0.0  
ref|XP_012845487.1| PREDICTED: DNA topoisomerase 1-like [Erythra...  1209   0.0  
gb|EYU30724.1| hypothetical protein MIMGU_mgv1a001121mg [Erythra...  1209   0.0  
emb|CDP13767.1| unnamed protein product [Coffea canephora]           1162   0.0  
dbj|BAG31376.1| topoisomerase I [Camptotheca acuminata]              1141   0.0  
dbj|BAG31377.1| topoisomerase I [Catharanthus roseus]                1129   0.0  
dbj|BAK32960.1| topoisomerase I [Ophiorrhiza pseudofasciculata]      1122   0.0  
dbj|BAG31375.1| topoisomerase I [Ophiorrhiza japonica]               1119   0.0  
dbj|BAK32958.1| topoisomerase I [Ophiorrhiza pedunculata]            1115   0.0  
dbj|BAK32962.1| topoisomerase I [Ophiorrhiza trichocarpon var. g...  1112   0.0  
ref|XP_006364175.2| PREDICTED: DNA topoisomerase 1-like [Solanum...  1104   0.0  
dbj|BAK32961.1| topoisomerase I [Ophiorrhiza ridleyana]              1099   0.0  
dbj|BAG31373.1| topoisomerase I [Ophiorrhiza pumila]                 1098   0.0  
dbj|BAK32956.1| topoisomerase I [Ophiorrhiza fucosa]                 1097   0.0  
dbj|BAG31374.1| topoisomerase I [Ophiorrhiza liukiuensis]            1096   0.0  
ref|XP_009619726.1| PREDICTED: LOW QUALITY PROTEIN: DNA topoisom...  1095   0.0  
ref|XP_009790344.1| PREDICTED: LOW QUALITY PROTEIN: DNA topoisom...  1082   0.0  
dbj|BAK32959.1| topoisomerase I [Ophiorrhiza plumbea]                1082   0.0  
dbj|BAK32963.1| topoisomerase I [Ophiorrhiza sp. 35]                 1082   0.0  
ref|XP_010266803.1| PREDICTED: DNA topoisomerase 1-like [Nelumbo...  1064   0.0  

>ref|XP_011093631.1| PREDICTED: DNA topoisomerase 1-like [Sesamum indicum]
          Length = 893

 Score = 1427 bits (3695), Expect = 0.0
 Identities = 719/893 (80%), Positives = 754/893 (84%)
 Frame = +2

Query: 530  MAVEACDKQKLXXXXXXXXXPLVFKRXXXXXXXXXXXXEAKKSLSQKHDRQLGRPAPDVR 709
            MA+E+C+ QKL         PLVFKR            E K+ LSQKHDR L RP+PDVR
Sbjct: 1    MAIESCNDQKLMDDMDEDDEPLVFKRSSSSAKQSQGNSETKRPLSQKHDRPLNRPSPDVR 60

Query: 710  SQNGQSTIVKKSKTVPLSKTPPVKYPLTSPKSSNTSGKALALKSPEVDSKPSTSVTDKSN 889
             QNGQST+++KSKTVP S+TPP++ PL SPKSSN+S KALA++  EVD +PSTSVTD+SN
Sbjct: 61   PQNGQSTMIQKSKTVPSSRTPPLRSPLASPKSSNSSAKALAVRPREVDPRPSTSVTDESN 120

Query: 890  SVKHQIKDEKLSTEATGEPNEDSQDSEDDKPLSARLPAGLSKVNSNHAKKSPNTSTLSQK 1069
            SVKHQIKDEK ST+ATG  NEDS+DSEDDKPLSARLPAGLSKVNSNHA K PN  T  QK
Sbjct: 121  SVKHQIKDEKPSTKATGGLNEDSEDSEDDKPLSARLPAGLSKVNSNHANKGPNALTSVQK 180

Query: 1070 RRIPIPEDSDDEIPLSSKFQVKSNAGESINRSSNSGERKPLLSKYDQNGSASTERKPSTN 1249
             +IP PEDSDDEIPLSSKFQVKSNAGES NR S SGERKPLL+KYDQNGSAS ERKPST 
Sbjct: 181  TKIPKPEDSDDEIPLSSKFQVKSNAGESTNRPSISGERKPLLAKYDQNGSASAERKPSTI 240

Query: 1250 LKKRPGDGVKTTDESYLKKPKLSEAATPHKNKEASIKAEMREEDDEDHVPISHRMXXXXX 1429
            LKKRP DGVK+  ESYLKKPKLS+A+TP+K KE SIK EM++EDDEDHVPIS R+     
Sbjct: 241  LKKRPADGVKSAGESYLKKPKLSDASTPNKTKETSIKDEMKDEDDEDHVPISQRIKQQTS 300

Query: 1430 XXXXXXXXXNITKPIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXGEGQKWTTLVHNGVI 1609
                     N+TKPI                              GEGQKWTTLVHNGVI
Sbjct: 301  SDKKSSSAKNMTKPISASAKKTSKKPKKVMKNSKYSKSSKVPPSSGEGQKWTTLVHNGVI 360

Query: 1610 FPPPYKPHGVKMLYKGKPVDLTPEQEEVATMYAVMLETDYMNKPKFKENFMADWRKILGK 1789
            FPPPYKPHGVKMLYKGKPVDLTPEQEEVATMYAVML+TDYMNKPKFKENFMADWRKILGK
Sbjct: 361  FPPPYKPHGVKMLYKGKPVDLTPEQEEVATMYAVMLDTDYMNKPKFKENFMADWRKILGK 420

Query: 1790 NHTIQSLEHCDFTPIYEWHXXXXXXXXXXXXXXXXXXXXXXXXXXXXYMWAIVNGVKEKV 1969
            NH IQSLEHCDFTPIYEWH                            YMWAIVNGVKEKV
Sbjct: 421  NHVIQSLEHCDFTPIYEWHQKEKEKKKQMTAEEKKALKEEKLKQEEKYMWAIVNGVKEKV 480

Query: 1970 GNFRVEPPGLFRGRGEHPKMGKLKKRIRPSDITINIGKDAPIPECPIPGESWKEIRHDNT 2149
            GNFRVEPPGLFRGRGEHPKMGKLKKRIRPSDITINIGKDAPIPECPIPGESWKEIRHDNT
Sbjct: 481  GNFRVEPPGLFRGRGEHPKMGKLKKRIRPSDITINIGKDAPIPECPIPGESWKEIRHDNT 540

Query: 2150 VTWLAYWNDPINPKEFKYVFLAASSTLKGQSDKEKYEKARLLKDYILGIRAAYTKDFTSK 2329
            VTWLAYWNDPINPKEFKYVFLAASSTLKGQSDKEKYEKARLLKDYI GIRAAYTKDFT+K
Sbjct: 541  VTWLAYWNDPINPKEFKYVFLAASSTLKGQSDKEKYEKARLLKDYIHGIRAAYTKDFTNK 600

Query: 2330 DPAKRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVEPVPPNTLKFDFLGKDS 2509
            DP K+QIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVEPVPPN LKFDFLGKDS
Sbjct: 601  DPTKKQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVEPVPPNILKFDFLGKDS 660

Query: 2510 IRYQNEVEVETAVFKAIQQFRSGKKGGDDLFDRLDTSKLNAHLKELMPGLTAKVFRTYNA 2689
            IRYQNEVEVET VFKAIQQFRSGKKG DD+FDRLDTSKLNAHLKELMPGLTAKVFRTYNA
Sbjct: 661  IRYQNEVEVETPVFKAIQQFRSGKKGSDDMFDRLDTSKLNAHLKELMPGLTAKVFRTYNA 720

Query: 2690 SITLDDMLSRETRGGDVAEKVVVYQHANKEVAIICNHQRTVSKSHSAQMLRLNEKIEELK 2869
            SITLDD LSRET+GGDVAEKVVVYQHANKEVAIICNHQRTVSKSHSAQM RLNEKIEELK
Sbjct: 721  SITLDDKLSRETKGGDVAEKVVVYQHANKEVAIICNHQRTVSKSHSAQMTRLNEKIEELK 780

Query: 2870 GVVEELQTDLARAKKGKPPLKSADGKPKRNLNPDALERKIAQTTAKIEKMERDKETKEDL 3049
            GV+EELQTDLARAKKGKPPLKSADGKPKRNLNPDALE+KIAQT AKIEKMERDKETKEDL
Sbjct: 781  GVLEELQTDLARAKKGKPPLKSADGKPKRNLNPDALEKKIAQTNAKIEKMERDKETKEDL 840

Query: 3050 KTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFAWAMDVDPGFRF 3208
            KTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFAWAMDVDP FRF
Sbjct: 841  KTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFAWAMDVDPSFRF 893


>ref|XP_012845487.1| PREDICTED: DNA topoisomerase 1-like [Erythranthe guttata]
          Length = 894

 Score = 1209 bits (3127), Expect = 0.0
 Identities = 634/909 (69%), Positives = 699/909 (76%), Gaps = 16/909 (1%)
 Frame = +2

Query: 530  MAVEAC-DKQKLXXXXXXXXXPLVFKRXXXXXXXXXXXXEAKKSLSQKHDRQLGRPAPDV 706
            M VEA  DK  +         PLVFKR            E K S SQKH+ Q+GR + DV
Sbjct: 1    MTVEAREDKNMMEDMDDDDDAPLVFKRSGSSSKPKQSEPENKLS-SQKHNAQVGRQSSDV 59

Query: 707  RSQNGQSTIVKKSKTVPLSKT--PPVKYPLTSPKSSNTSGKALALKSPEVDSKPSTSVTD 880
            R QNG +   +K K+V  S +  PPV+  L SPKSSN+S KA  +KSP+V+SKPSTSV  
Sbjct: 60   RPQNGTNANAQKGKSVTSSSSMKPPVRPSLVSPKSSNSSVKASPIKSPDVNSKPSTSVVG 119

Query: 881  KSNSVKHQIKDEKLSTEATGEPNEDSQDSEDDKPLSARLPAGLSKVNSNHAKKSPNTSTL 1060
            +S SVK  IK+E            +S+DSEDDKPLSAR  AG SK N N   K PN   L
Sbjct: 120  ESKSVKSTIKEE------------NSEDSEDDKPLSARQVAGSSKNNPNQTNK-PNAPNL 166

Query: 1061 SQKRRIPIPEDSDDEIPLSSKFQVKSNAGESINRSSNSGERKPLLS-KYDQNGSASTERK 1237
             +K  +P PEDSDDEIPLS+KFQ KSNAG S +RSS+S E+KPL++ K D+NGSASTERK
Sbjct: 167  GKKSNVPKPEDSDDEIPLSAKFQGKSNAGASTSRSSHSEEKKPLVARKPDKNGSASTERK 226

Query: 1238 PSTNLKKRPGDGVKTTDESYLKKPKLSEAATPHKNKEASIKAEMREEDDEDHVPISHRMX 1417
            PST L+KRP DGV +  +S LKKPKLS++    K+K+AS+K E++ EDDED VP+S R  
Sbjct: 227  PSTVLQKRPADGVASAGQSNLKKPKLSDSLAS-KDKKASVKPEVKAEDDEDLVPLSQRTK 285

Query: 1418 XXXXXXXXXXXXXNITKPIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----------- 1564
                          +TK                                           
Sbjct: 286  KSTTPEKKPSPALKVTKSTASISKKTNNKTNSKTNSKTNKKSKQVSKDNNYSKSSKLPPS 345

Query: 1565 -GEGQKWTTLVHNGVIFPPPYKPHGVKMLYKGKPVDLTPEQEEVATMYAVMLETDYMNKP 1741
             G+GQKWTTLVHNGVIFPPPYKPHGVKMLYKGKPV+LTPEQEEVATMYAVMLETDY+ KP
Sbjct: 346  SGDGQKWTTLVHNGVIFPPPYKPHGVKMLYKGKPVNLTPEQEEVATMYAVMLETDYLKKP 405

Query: 1742 KFKENFMADWRKILGKNHTIQSLEHCDFTPIYEWHXXXXXXXXXXXXXXXXXXXXXXXXX 1921
            +FKENFM DW+KILGKNH IQSLEHCDFTPIYEWH                         
Sbjct: 406  QFKENFMTDWKKILGKNHVIQSLEHCDFTPIYEWHQREKEKKKQMSTDEKKALKEEKLKL 465

Query: 1922 XXXYMWAIVNGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIRPSDITINIGKDAPIPE 2101
               YMWA+++GV+EKVGNFRVEPPGLFRGRGEHPKMGKLK+RIRPSDITINIG+DAPIPE
Sbjct: 466  EEKYMWAVLDGVREKVGNFRVEPPGLFRGRGEHPKMGKLKRRIRPSDITINIGRDAPIPE 525

Query: 2102 CPIPGESWKEIRHDNTVTWLAYWNDPINPKEFKYVFLAASSTLKGQSDKEKYEKARLLKD 2281
            CPI GE WKEIRHDNTVTWLAYW+DPIN KEFKYVFLAASSTLKGQSDKEKYEKARLLKD
Sbjct: 526  CPIEGERWKEIRHDNTVTWLAYWSDPINGKEFKYVFLAASSTLKGQSDKEKYEKARLLKD 585

Query: 2282 YILGIRAAYTKDFTSKDPAKRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVE 2461
            YI GIR AYT+DF SKDPAK+QIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVE
Sbjct: 586  YIQGIRTAYTRDFVSKDPAKKQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVE 645

Query: 2462 PVPPNTLKFDFLGKDSIRYQNEVEVETAVFKAIQQFRSGKKGGDDLFDRLDTSKLNAHLK 2641
            PVPPN LKFDFLGKDSIRYQNEVEVETAVFKAIQQFRSGKKGGDDLFD+LDTSKLNAHLK
Sbjct: 646  PVPPNILKFDFLGKDSIRYQNEVEVETAVFKAIQQFRSGKKGGDDLFDKLDTSKLNAHLK 705

Query: 2642 ELMPGLTAKVFRTYNASITLDDMLSRETRGGDVAEKVVVYQHANKEVAIICNHQRTVSKS 2821
            ELMPGLTAKVFRTYNASITLDD LSRET+GGD+AEKVV Y HANKEVAIICNHQRTVSK+
Sbjct: 706  ELMPGLTAKVFRTYNASITLDDKLSRETKGGDLAEKVVTYNHANKEVAIICNHQRTVSKT 765

Query: 2822 HSAQMLRLNEKIEELKGVVEELQTDLARAKKGKPPLKSADGKPKRNLNPDALERKIAQTT 3001
            HSAQMLRL+EKI+ELKGV+EEL+TDL RA+KGKP L  ADGK KRN+NP+ALERKIAQTT
Sbjct: 766  HSAQMLRLDEKIDELKGVLEELKTDLGRARKGKPLLAGADGKAKRNINPEALERKIAQTT 825

Query: 3002 AKIEKMERDKETKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFAWA 3181
            AKIEKMERDKETKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEK+FNKSLL KF+WA
Sbjct: 826  AKIEKMERDKETKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKMFNKSLLEKFSWA 885

Query: 3182 MDVDPGFRF 3208
            MDVDP FRF
Sbjct: 886  MDVDPSFRF 894


>gb|EYU30724.1| hypothetical protein MIMGU_mgv1a001121mg [Erythranthe guttata]
          Length = 883

 Score = 1209 bits (3127), Expect = 0.0
 Identities = 633/898 (70%), Positives = 697/898 (77%), Gaps = 5/898 (0%)
 Frame = +2

Query: 530  MAVEAC-DKQKLXXXXXXXXXPLVFKRXXXXXXXXXXXXEAKKSLSQKHDRQLGRPAPDV 706
            M VEA  DK  +         PLVFKR            E K S SQKH+ Q+GR + DV
Sbjct: 1    MTVEAREDKNMMEDMDDDDDAPLVFKRSGSSSKPKQSEPENKLS-SQKHNAQVGRQSSDV 59

Query: 707  RSQNGQSTIVKKSKTVPLSKT--PPVKYPLTSPKSSNTSGKALALKSPEVDSKPSTSVTD 880
            R QNG +   +K K+V  S +  PPV+  L SPKSSN+S KA  +KSP+V+SKPSTSV  
Sbjct: 60   RPQNGTNANAQKGKSVTSSSSMKPPVRPSLVSPKSSNSSVKASPIKSPDVNSKPSTSVVG 119

Query: 881  KSNSVKHQIKDEKLSTEATGEPNEDSQDSEDDKPLSARLPAGLSKVNSNHAKKSPNTSTL 1060
            +S SVK  IK+E            +S+DSEDDKPLSAR  AG SK N N   K PN   L
Sbjct: 120  ESKSVKSTIKEE------------NSEDSEDDKPLSARQVAGSSKNNPNQTNK-PNAPNL 166

Query: 1061 SQKRRIPIPEDSDDEIPLSSKFQVKSNAGESINRSSNSGERKPLLS-KYDQNGSASTERK 1237
             +K  +P PEDSDDEIPLS+KFQ KSNAG S +RSS+S E+KPL++ K D+NGSASTERK
Sbjct: 167  GKKSNVPKPEDSDDEIPLSAKFQGKSNAGASTSRSSHSEEKKPLVARKPDKNGSASTERK 226

Query: 1238 PSTNLKKRPGDGVKTTDESYLKKPKLSEAATPHKNKEASIKAEMREEDDEDHVPISHRMX 1417
            PST L+KRP DGV +  +S LKKPKLS++    K+K+AS+K E++ EDDED VP+S R  
Sbjct: 227  PSTVLQKRPADGVASAGQSNLKKPKLSDSLAS-KDKKASVKPEVKAEDDEDLVPLSQRTK 285

Query: 1418 XXXXXXXXXXXXXNIT-KPIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXGEGQKWTTLV 1594
                             K                                G+GQKWTTLV
Sbjct: 286  KSTTPEKKPSPALKTNNKTNSKTNSKTNKKSKQVSKDNNYSKSSKLPPSSGDGQKWTTLV 345

Query: 1595 HNGVIFPPPYKPHGVKMLYKGKPVDLTPEQEEVATMYAVMLETDYMNKPKFKENFMADWR 1774
            HNGVIFPPPYKPHGVKMLYKGKPV+LTPEQEEVATMYAVMLETDY+ KP+FKENFM DW+
Sbjct: 346  HNGVIFPPPYKPHGVKMLYKGKPVNLTPEQEEVATMYAVMLETDYLKKPQFKENFMTDWK 405

Query: 1775 KILGKNHTIQSLEHCDFTPIYEWHXXXXXXXXXXXXXXXXXXXXXXXXXXXXYMWAIVNG 1954
            KILGKNH IQSLEHCDFTPIYEWH                            YMWA+++G
Sbjct: 406  KILGKNHVIQSLEHCDFTPIYEWHQREKEKKKQMSTDEKKALKEEKLKLEEKYMWAVLDG 465

Query: 1955 VKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIRPSDITINIGKDAPIPECPIPGESWKEI 2134
            V+EKVGNFRVEPPGLFRGRGEHPKMGKLK+RIRPSDITINIG+DAPIPECPI GE WKEI
Sbjct: 466  VREKVGNFRVEPPGLFRGRGEHPKMGKLKRRIRPSDITINIGRDAPIPECPIEGERWKEI 525

Query: 2135 RHDNTVTWLAYWNDPINPKEFKYVFLAASSTLKGQSDKEKYEKARLLKDYILGIRAAYTK 2314
            RHDNTVTWLAYW+DPIN KEFKYVFLAASSTLKGQSDKEKYEKARLLKDYI GIR AYT+
Sbjct: 526  RHDNTVTWLAYWSDPINGKEFKYVFLAASSTLKGQSDKEKYEKARLLKDYIQGIRTAYTR 585

Query: 2315 DFTSKDPAKRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVEPVPPNTLKFDF 2494
            DF SKDPAK+QIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVEPVPPN LKFDF
Sbjct: 586  DFVSKDPAKKQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVEPVPPNILKFDF 645

Query: 2495 LGKDSIRYQNEVEVETAVFKAIQQFRSGKKGGDDLFDRLDTSKLNAHLKELMPGLTAKVF 2674
            LGKDSIRYQNEVEVETAVFKAIQQFRSGKKGGDDLFD+LDTSKLNAHLKELMPGLTAKVF
Sbjct: 646  LGKDSIRYQNEVEVETAVFKAIQQFRSGKKGGDDLFDKLDTSKLNAHLKELMPGLTAKVF 705

Query: 2675 RTYNASITLDDMLSRETRGGDVAEKVVVYQHANKEVAIICNHQRTVSKSHSAQMLRLNEK 2854
            RTYNASITLDD LSRET+GGD+AEKVV Y HANKEVAIICNHQRTVSK+HSAQMLRL+EK
Sbjct: 706  RTYNASITLDDKLSRETKGGDLAEKVVTYNHANKEVAIICNHQRTVSKTHSAQMLRLDEK 765

Query: 2855 IEELKGVVEELQTDLARAKKGKPPLKSADGKPKRNLNPDALERKIAQTTAKIEKMERDKE 3034
            I+ELKGV+EEL+TDL RA+KGKP L  ADGK KRN+NP+ALERKIAQTTAKIEKMERDKE
Sbjct: 766  IDELKGVLEELKTDLGRARKGKPLLAGADGKAKRNINPEALERKIAQTTAKIEKMERDKE 825

Query: 3035 TKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFAWAMDVDPGFRF 3208
            TKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEK+FNKSLL KF+WAMDVDP FRF
Sbjct: 826  TKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKMFNKSLLEKFSWAMDVDPSFRF 883


>emb|CDP13767.1| unnamed protein product [Coffea canephora]
          Length = 926

 Score = 1162 bits (3006), Expect = 0.0
 Identities = 609/927 (65%), Positives = 678/927 (73%), Gaps = 34/927 (3%)
 Frame = +2

Query: 530  MAVEACDKQKLXXXXXXXXXPLVFKRXXXXXXXXXXXXEAKKSLSQKHDRQLGRPAPDVR 709
            MAVEAC    L         PLVFKR            E KK  SQK D Q  R + DV 
Sbjct: 1    MAVEACSTPSLLEDSDEENAPLVFKRTSSSSKQNLSNSETKKLSSQKRDGQSSRNSSDVC 60

Query: 710  SQNGQSTIVKKSKTVPLSKTPPVKYPLTSPKSSNTSGKALALKSPEVDSKPSTSVTDKSN 889
              NGQS+  +  + V  +KTPP K PL+SPK++N S K   + SP  +SKPS+S +    
Sbjct: 61   PVNGQSSSAQTGRVVSSAKTPPAKSPLSSPKAANISAKTSLITSPGANSKPSSSTSATVK 120

Query: 890  SVKHQ-----IKDEKLSTEATGEPNEDSQDSEDDKPLSARLPAGLSKVNSNHAKKSPNTS 1054
             +++      +K  K S  A  + +   +DS+DDKPL A+LP+G S+   NH  K  + S
Sbjct: 121  QLENHKNSPVVKLPKRSVSAA-KLSSTPEDSDDDKPLMAKLPSGSSRAIVNHGNKDGDGS 179

Query: 1055 TLSQKRRIPIPEDSDDEIPLSSKFQVKSNAGESINRSSNSGERKPLLSKYDQNGSASTER 1234
            +L QK  +   EDSDDE PLSS++  KSN  ESI++S N GE+K L +K  QNGSA  + 
Sbjct: 180  SLVQKPGVEEDEDSDDEKPLSSRYLSKSNLVESISKSRNPGEKKSLPAKVQQNGSALRDG 239

Query: 1235 ---KPSTNLKKRPGDGVKTTDESYLKKPKLSEAATPHKNKEASIKAEMREEDDED----- 1390
               K S+   KRP   VK++DES +KKPKLS        K+A++KAE + EDD+D     
Sbjct: 240  PVGKSSSLSNKRPPGEVKSSDESAVKKPKLSGPTAAINKKQATLKAEPKVEDDDDDILIS 299

Query: 1391 ---------------------HVPISHRMXXXXXXXXXXXXXXNITKPIXXXXXXXXXXX 1507
                                 HVPI+ RM               + K +           
Sbjct: 300  QTAKKMFASASKPKSNDDDDDHVPITQRMKKSTTSVSQSSSVKKVAKVVSSSLKKTNKKS 359

Query: 1508 XXXXXXXXXXXXXXXXXXXGEGQKWTTLVHNGVIFPPPYKPHGVKMLYKGKPVDLTPEQE 1687
                               GEGQKWTTLVHNGVIFPPPYKPHGVKMLYKG+PV LTPEQE
Sbjct: 360  KKIIKKSKYSKSSKVPPGSGEGQKWTTLVHNGVIFPPPYKPHGVKMLYKGQPVTLTPEQE 419

Query: 1688 EVATMYAVMLETDYMNKPKFKENFMADWRKILGKNHTIQSLEHCDFTPIYEWHXXXXXXX 1867
            EVATM+AVML+TDYM+KP+FKENF +DW++ILGKNHTIQ+LE CDF PIYEWH       
Sbjct: 420  EVATMFAVMLDTDYMSKPQFKENFFSDWKRILGKNHTIQNLEDCDFRPIYEWHQKEKEKK 479

Query: 1868 XXXXXXXXXXXXXXXXXXXXXYMWAIVNGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKR 2047
                                 YMWAIV+GVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKR
Sbjct: 480  KQMTTEEKKSLKEEKLKQEEKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKR 539

Query: 2048 IRPSDITINIGKDAPIPECPIPGESWKEIRHDNTVTWLAYWNDPINPKEFKYVFLAASST 2227
            IRP DITINIGKDAPIPECPIPGE WKEIRHDNTVTWLA+WNDPINPKEFKYVFLAASST
Sbjct: 540  IRPRDITINIGKDAPIPECPIPGERWKEIRHDNTVTWLAFWNDPINPKEFKYVFLAASST 599

Query: 2228 LKGQSDKEKYEKARLLKDYILGIRAAYTKDFTSKDPAKRQIAVATYLIDKLALRAGNEKD 2407
            LKGQSDKEKYEKARLLKDYI GIR AYTKDF SKDP K+QIAVATYLIDKLALRAGNEKD
Sbjct: 600  LKGQSDKEKYEKARLLKDYIHGIRTAYTKDFASKDPMKKQIAVATYLIDKLALRAGNEKD 659

Query: 2408 DDEADTVGCCTLKVENVEPVPPNTLKFDFLGKDSIRYQNEVEVETAVFKAIQQFRSGKKG 2587
            DDEADTVGCCTLKVENVEPVPPN LKFDFLGKDSIRYQNEVEVE+ VFKAIQQFRSGK+G
Sbjct: 660  DDEADTVGCCTLKVENVEPVPPNILKFDFLGKDSIRYQNEVEVESGVFKAIQQFRSGKEG 719

Query: 2588 GDDLFDRLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSRETRGGDVAEKVVVYQH 2767
             +DLFD+LDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSR+T GGDV EKVVVYQ 
Sbjct: 720  SEDLFDKLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSRKTNGGDVLEKVVVYQQ 779

Query: 2768 ANKEVAIICNHQRTVSKSHSAQMLRLNEKIEELKGVVEELQTDLARAKKGKPPLKSADGK 2947
            ANKEVAIICNHQRTVSK+HSAQM RLNEKIEELKGV+EEL+TDL+RAKKGKPPLK+ADGK
Sbjct: 780  ANKEVAIICNHQRTVSKTHSAQMSRLNEKIEELKGVLEELKTDLSRAKKGKPPLKNADGK 839

Query: 2948 PKRNLNPDALERKIAQTTAKIEKMERDKETKEDLKTVALGTSKINYLDPRITVAWCKRHE 3127
            PKRNLNP+ALERKIAQT AKIEKMERDKETKEDLKTVALGTSKINYLDPRITVAWCKRHE
Sbjct: 840  PKRNLNPEALERKIAQTNAKIEKMERDKETKEDLKTVALGTSKINYLDPRITVAWCKRHE 899

Query: 3128 VPIEKIFNKSLLAKFAWAMDVDPGFRF 3208
            VPIEKIFNKSLLAKFAW+MDVDP FRF
Sbjct: 900  VPIEKIFNKSLLAKFAWSMDVDPSFRF 926


>dbj|BAG31376.1| topoisomerase I [Camptotheca acuminata]
          Length = 894

 Score = 1141 bits (2952), Expect = 0.0
 Identities = 600/903 (66%), Positives = 675/903 (74%), Gaps = 10/903 (1%)
 Frame = +2

Query: 530  MAVEACDKQKLXXXXXXXXXPLVFKRXXXXXXXXXXXXEAKKSLSQKHDRQLGRPAPDVR 709
            MAV+AC K+K+         PLVFKR            + KKS SQ++D Q GR   DV 
Sbjct: 1    MAVQACVKEKMMDEIDEDDEPLVFKRSNATSKHNQLNSDTKKS-SQRYDGQSGRQVSDVP 59

Query: 710  SQNGQSTIVKKSKTVPLSKTPPVKYPLTSPKSSNTSGKALALKSPEVDSKPSTSVTDKSN 889
            S NGQS+   K KT  LS    +K P+ SPK+S +  KA  + +P+V S  S+    K +
Sbjct: 60   STNGQSSSASKGKTTKLSS---MKSPIASPKASTSFAKASPVANPKVSS--SSDDRSKHS 114

Query: 890  SVKHQIKDEKLSTEATGEPNEDSQDSEDDKPLSARLPAGLSKVNSNHAKKSPNTSTLSQK 1069
            S ++ I   K   E      E   DSED+KPLSARL  GL+K +SN+A K    S+ +  
Sbjct: 115  SKQNTINVVKEEKELVNPAAEPYGDSEDEKPLSARLFTGLTKGSSNNANKGLINSSPAS- 173

Query: 1070 RRIPIP--------EDSDDEIPLSSKFQVKSNAGESINRSSNSGERKPLLSKYDQNGSAS 1225
              +P+P        +DSDDEIPLSSKF++K+NAG S  +S  S + K L+S + QNGS +
Sbjct: 174  --LPVPKPEINRYSDDSDDEIPLSSKFRLKANAGTSTVKSYESDDNKTLVSNFQQNGSIN 231

Query: 1226 TERKPSTNLKKRPGDGVKTTDESYLKKPKLSEAATPHKNKEASIKAEMREED-DEDHVPI 1402
               K S  + KRP   VK++ +S +KKPKLS+A+TP  NK+AS KAE + +D D+DHVPI
Sbjct: 232  RGSKSSIKVNKRPLGEVKSSVQSSVKKPKLSDASTPVNNKQASKKAEPKADDSDDDHVPI 291

Query: 1403 SHRMXXXXXXXXXXXXXXN-ITKPIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXGEGQK 1579
            S RM                +TK +                              GEG+K
Sbjct: 292  SQRMKKSATSGNKSSTAKQKVTKVVSSSMKKASKKFKKVVKKSKYSKSSKVPPSSGEGKK 351

Query: 1580 WTTLVHNGVIFPPPYKPHGVKMLYKGKPVDLTPEQEEVATMYAVMLETDYMNKPKFKENF 1759
            W TLVHNGVIFPPPYKPHGVKMLYKGKPVDLTPEQEEVATM+AVML+TDYM K KFKENF
Sbjct: 352  WNTLVHNGVIFPPPYKPHGVKMLYKGKPVDLTPEQEEVATMFAVMLDTDYMTKSKFKENF 411

Query: 1760 MADWRKILGKNHTIQSLEHCDFTPIYEWHXXXXXXXXXXXXXXXXXXXXXXXXXXXXYMW 1939
            M DWRKILGKNH IQ+LE CDFTPIYEWH                            YMW
Sbjct: 412  MDDWRKILGKNHVIQNLEDCDFTPIYEWHQREKEKKKKMTAEEKKVLKEERLKQEEKYMW 471

Query: 1940 AIVNGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIRPSDITINIGKDAPIPECPIPGE 2119
            AIVNGVKEKVGNFRVEPP LFRGRGEHPKMGKLKK IRPSDITINIGKDAPIPECPIPGE
Sbjct: 472  AIVNGVKEKVGNFRVEPPSLFRGRGEHPKMGKLKKCIRPSDITINIGKDAPIPECPIPGE 531

Query: 2120 SWKEIRHDNTVTWLAYWNDPINPKEFKYVFLAASSTLKGQSDKEKYEKARLLKDYILGIR 2299
            SWKEIRHDNTVTWLA+WNDPI P+EFKYVFLAASS+LKGQSDKEKYEKARLLKD+I GIR
Sbjct: 532  SWKEIRHDNTVTWLAFWNDPIKPREFKYVFLAASSSLKGQSDKEKYEKARLLKDFIQGIR 591

Query: 2300 AAYTKDFTSKDPAKRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVEPVPPNT 2479
            AAYTKDF SKD  KRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVEP PP+ 
Sbjct: 592  AAYTKDFASKDITKRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVEPKPPSI 651

Query: 2480 LKFDFLGKDSIRYQNEVEVETAVFKAIQQFRSGKKGGDDLFDRLDTSKLNAHLKELMPGL 2659
            LKFDFLGKDSIRYQNEVEVE  V+KAIQQFR+GK+GGDDLFD+LDTSKLNAHLK LMPGL
Sbjct: 652  LKFDFLGKDSIRYQNEVEVELPVYKAIQQFRTGKRGGDDLFDKLDTSKLNAHLKGLMPGL 711

Query: 2660 TAKVFRTYNASITLDDMLSRETRGGDVAEKVVVYQHANKEVAIICNHQRTVSKSHSAQML 2839
            TAKVFRTYNASITLD+MLSRET+GG+VAEK+VVYQHANKEVAIICNHQRTVSKSH AQM 
Sbjct: 712  TAKVFRTYNASITLDEMLSRETKGGNVAEKIVVYQHANKEVAIICNHQRTVSKSHPAQMT 771

Query: 2840 RLNEKIEELKGVVEELQTDLARAKKGKPPLKSADGKPKRNLNPDALERKIAQTTAKIEKM 3019
            RLN KI+ELKG+++ LQTDLARAKKGKPPL+ ADGKPKRNL P+ALERKI QT AKIEKM
Sbjct: 772  RLNGKIDELKGILDGLQTDLARAKKGKPPLEDADGKPKRNLTPEALERKIGQTNAKIEKM 831

Query: 3020 ERDKETKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFAWAMDVDPG 3199
            ERDKETKE LKT+ALGTSKI+YLDPRITVAWCKRHEVPIEK+FNKSLLAKFAW+MDVDP 
Sbjct: 832  ERDKETKEGLKTIALGTSKISYLDPRITVAWCKRHEVPIEKVFNKSLLAKFAWSMDVDPS 891

Query: 3200 FRF 3208
            FRF
Sbjct: 892  FRF 894


>dbj|BAG31377.1| topoisomerase I [Catharanthus roseus]
          Length = 910

 Score = 1129 bits (2921), Expect = 0.0
 Identities = 600/919 (65%), Positives = 662/919 (72%), Gaps = 26/919 (2%)
 Frame = +2

Query: 530  MAVEACDKQKLXXXXXXXXXPLVFKRXXXXXXXXXXXXEAKKSLSQKHDRQLGRPAPDVR 709
            MAVEAC    L         P+VFKR            E +K  SQK D Q  R   D R
Sbjct: 1    MAVEACPTPNLRDDMDEDDEPIVFKRNNSASKQSQTNSETRKVSSQKRDGQSVRQIYDSR 60

Query: 710  SQNGQSTIVKKSKTVPLSK---------TPP-----VKYPLTSPKSSNTSGKALALKSPE 847
              NG+S+  +K + VP SK         +PP     VK PL+SPK S +S K   + S  
Sbjct: 61   PANGESSSGQKGRMVPPSKPSQVKSPLSSPPSKPSQVKSPLSSPKVSTSSAKKSPVSSLP 120

Query: 848  VDSKPSTSVTDKSNSVKHQ-----IKDEKLST-EATGEPNEDSQDSEDDKPLSARLPAGL 1009
             +SKPSTS + K            IK+EK S          DS+DS+D KPLS R  A  
Sbjct: 121  ANSKPSTSGSFKVKPFNQHKSATVIKEEKSSPLRLASAIINDSEDSDDGKPLSLRHSASS 180

Query: 1010 SKVNSNHAKKSPNTSTLSQKRRIPIPEDSDDEIPLSSKFQVKSNAGESINRSSNSGERKP 1189
            SK N+N   K  +          P  EDSDDE PLSS+F +KS  GES +++ +S + KP
Sbjct: 181  SKGNTNQVSKEGSK---------PENEDSDDEKPLSSRFPLKSGVGESTSKAYDSDDDKP 231

Query: 1190 LLSKYDQNGSASTERKP---STNLKKRPGDGVKTTDESYLKKPKLSEAATPHKNKEASIK 1360
            L  K   NGSA  + +P   S    KRP   +K++++  +KKPKLS    P   K+AS+K
Sbjct: 232  LAKKLQHNGSAMRDGQPNKYSNMSNKRPPGDIKSSNQLSVKKPKLSSVTAPTNKKQASVK 291

Query: 1361 AEMR-EEDDEDHVPISHRMXXXXXXXXXXXXXXNITKPIXXXXXXXXXXXXXXXXXXXXX 1537
             E + E+DD+DH+PIS R+                TK +                     
Sbjct: 292  PEPKAEDDDDDHLPISQRIKKSPTSESKSSSIKKTTKVVSSSVKKVNKKSKKVMKNSKYS 351

Query: 1538 XXXXXXXXXGEGQKWTTLVHNGVIFPPPYKPHGVKMLYKGKPVDLTPEQEEVATMYAVML 1717
                     GEG+KW  L HNGVIFPPPYKPHG+KMLYKGKPVDLTPEQEEVATM+AVML
Sbjct: 352  KSSKVPPSSGEGKKWNKLEHNGVIFPPPYKPHGIKMLYKGKPVDLTPEQEEVATMFAVML 411

Query: 1718 ETDYMNKPKFKENFMADWRKILGKNHTIQSLEHCDFTPIYEWHXXXXXXXXXXXXXXXXX 1897
            +TDYMNKP+FKENF  DW+KILGKNH IQ+LE+CDF+PIYEWH                 
Sbjct: 412  DTDYMNKPRFKENFFGDWKKILGKNHVIQNLENCDFSPIYEWHQSEKEKKKQMTTEEKKA 471

Query: 1898 XXXXXXXXXXXYMWAIVNGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIRPSDITINI 2077
                       YMWA V+G KEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIRP DITINI
Sbjct: 472  LKEEKLKQEEKYMWAWVDGKKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIRPCDITINI 531

Query: 2078 GKDAPIPECPIPGESWKEIRHDNTVTWLAYWNDPINPKEFKYVFLAASSTLKGQSDKEKY 2257
            GKDAPIPECP+PGE WKE+RHDNTVTWLA+WNDPINPKEFKYVFLAASSTLKG SDKEKY
Sbjct: 532  GKDAPIPECPVPGERWKEVRHDNTVTWLAFWNDPINPKEFKYVFLAASSTLKGLSDKEKY 591

Query: 2258 EKARLLKDYILGIRAAYTKDFTSKDPAKRQIAVATYLIDKLALRAGNEKDDDEADTVGCC 2437
            EKARLLKDYI GIRAAYTKDF SKDP K+QIAVATYLIDKLALRAGNEKDDDEADTVGCC
Sbjct: 592  EKARLLKDYIQGIRAAYTKDFASKDPTKKQIAVATYLIDKLALRAGNEKDDDEADTVGCC 651

Query: 2438 TLKVENVEPVPPNTLKFDFLGKDSIRYQNEVEVETAVFKAIQQFRSGKKGGDDLFDRLDT 2617
            TLKVENVEPVPPN LKFDFLGKDSIRYQNEVEVE AVFKAIQQFRSGK+G  DLFD LDT
Sbjct: 652  TLKVENVEPVPPNILKFDFLGKDSIRYQNEVEVEAAVFKAIQQFRSGKEGSSDLFDLLDT 711

Query: 2618 SKLNAHLKELMPGLTAKVFRTYNASITLDDMLSRETRGGDVAEKVVVYQHANKEVAIICN 2797
            SKLNAHLKELMPGLTAKVFRTYNASITLDDMLSRET+GGDVAEKVVVYQHANKEVAIICN
Sbjct: 712  SKLNAHLKELMPGLTAKVFRTYNASITLDDMLSRETKGGDVAEKVVVYQHANKEVAIICN 771

Query: 2798 HQRTVSKSHSAQMLRLNEKIEELKGVVEELQTDLARAKKGKPPLKS--ADGKPKRNLNPD 2971
            HQRTVSKSHSAQMLRLNEKIEELK VVEEL++DL+R KKGKPPLKS  ADGKPKRNLNP+
Sbjct: 772  HQRTVSKSHSAQMLRLNEKIEELKAVVEELKSDLSRVKKGKPPLKSKNADGKPKRNLNPE 831

Query: 2972 ALERKIAQTTAKIEKMERDKETKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFN 3151
            +LE+KIAQT AKIEKMERDKETKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFN
Sbjct: 832  SLEKKIAQTNAKIEKMERDKETKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFN 891

Query: 3152 KSLLAKFAWAMDVDPGFRF 3208
            KSLLAKF WAMDVDP FRF
Sbjct: 892  KSLLAKFTWAMDVDPSFRF 910


>dbj|BAK32960.1| topoisomerase I [Ophiorrhiza pseudofasciculata]
          Length = 925

 Score = 1122 bits (2901), Expect = 0.0
 Identities = 595/926 (64%), Positives = 664/926 (71%), Gaps = 33/926 (3%)
 Frame = +2

Query: 530  MAVEACDKQKLXXXXXXXXXPLVFKRXXXXXXXXXXXXEAKKSLSQKHDRQLGRPAPDVR 709
            MAVEAC    L         P++FKR            E KK   QK D Q      DVR
Sbjct: 1    MAVEACTTN-LMEDMEDDGGPVIFKRSKPAPKQNQANSEKKKLSLQKQDGQSAVHTSDVR 59

Query: 710  SQNGQSTIVKKSKTVPLSKTPPVKYPLTSPKSSNTSGKALALKSPEVDSKPSTSVTDKSN 889
              NG+S+  +K +  P +KTPPVK PL+SPK+SN+S KA  + SP  +SKPS S T  + 
Sbjct: 60   PANGESSSAQKGRIQPSAKTPPVKSPLSSPKASNSSAKASPITSPGANSKPSASATSTAK 119

Query: 890  SVKHQIKD----EKLSTEATGEPNEDSQDSEDDKPLSARLPAGLSKVNSNHAKKSPNTST 1057
               H        E   +    + N +S+ S+D+KPLSAR     SK  SNHA K    S 
Sbjct: 120  QQNHHKSSAAFIEPKPSVPAAKANSNSESSDDEKPLSARTFGCSSKGKSNHANKEGGDSC 179

Query: 1058 LSQKRRIPIPEDSDDEIPLSSKFQVKSNAGESINRSSNSGERKPLLSKYDQNGSASTE-- 1231
              ++  I   EDS+DE PLS +F  KS+ GES ++S +S E+KPL +K  QNGSAS +  
Sbjct: 180  SIRRPVIEESEDSEDEKPLSCRFTSKSSLGESTSKSYDSDEKKPLAAKVQQNGSASRDGP 239

Query: 1232 -RKPSTNLKKRPGDGVKTTDESYLKKPKLSEAATPHKNKEASIKAEMREEDDE------- 1387
              K ++   KRP    K+ ++S +KKPKLS   T   NK+A++K E + EDD+       
Sbjct: 240  MNKSASLSNKRPPGEAKSLNQSSVKKPKLSSPITSISNKQAAVKPEPKAEDDDDNIPLSQ 299

Query: 1388 -----------------DHVPISHRMXXXXXXXXXXXXXXN-ITKPIXXXXXXXXXXXXX 1513
                             D+VPIS R+                 +  +             
Sbjct: 300  RGKKSQSATSKPKDDDDDNVPISQRIKKSPASVSKSSVPVKKASTVVSSSLKKVNKNSKK 359

Query: 1514 XXXXXXXXXXXXXXXXXGEGQKWTTLVHNGVIFPPPYKPHGVKMLYKGKPVDLTPEQEEV 1693
                             GEGQKWTTLVHNGVIFPPPYKPHGVKMLYK +P+ LTPEQEEV
Sbjct: 360  VIKKTAYTKSSKVPPGSGEGQKWTTLVHNGVIFPPPYKPHGVKMLYKRQPITLTPEQEEV 419

Query: 1694 ATMYAVMLETDYMNKPKFKENFMADWRKILGKNHTIQSLEHCDFTPIYEWHXXXXXXXXX 1873
            ATM+AVML+TDYMNKP FKENF +DW+KILGKNH IQ+LE CDF PIYEWH         
Sbjct: 420  ATMFAVMLDTDYMNKPCFKENFFSDWKKILGKNHMIQNLEDCDFGPIYEWHQQEKEKKKQ 479

Query: 1874 XXXXXXXXXXXXXXXXXXXYMWAIVNGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIR 2053
                               YMWAIV+GVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIR
Sbjct: 480  MTTEEKKALKEEKLQQEEKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIR 539

Query: 2054 PSDITINIGKDAPIPECPIPGESWKEIRHDNTVTWLAYWNDPINPKEFKYVFLAASSTLK 2233
            P DITINIGKDAPIPECPIPGE WKE+R+ NTVTWLAYWNDPIN KEFKYVFLAASSTLK
Sbjct: 540  PRDITINIGKDAPIPECPIPGERWKEVRNGNTVTWLAYWNDPINQKEFKYVFLAASSTLK 599

Query: 2234 GQSDKEKYEKARLLKDYILGIRAAYTKDFTS-KDPAKRQIAVATYLIDKLALRAGNEKDD 2410
            GQSDKEKYEKARLLKDYI GIRAAYTKDFT+ KDP K+QIAVATYLIDKLALRAGNEKDD
Sbjct: 600  GQSDKEKYEKARLLKDYIHGIRAAYTKDFTNNKDPMKKQIAVATYLIDKLALRAGNEKDD 659

Query: 2411 DEADTVGCCTLKVENVEPVPPNTLKFDFLGKDSIRYQNEVEVETAVFKAIQQFRSGKKGG 2590
            DEADTVGCCTLKVENVEPVPPN LKFDFLGKDSIRYQNEV+VE AVFKAIQQFRSGK+G 
Sbjct: 660  DEADTVGCCTLKVENVEPVPPNILKFDFLGKDSIRYQNEVQVEPAVFKAIQQFRSGKEGS 719

Query: 2591 DDLFDRLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSRETRGGDVAEKVVVYQHA 2770
            +DLFDRLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLS+ET+GG+VAE VVVYQHA
Sbjct: 720  EDLFDRLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSKETKGGEVAENVVVYQHA 779

Query: 2771 NKEVAIICNHQRTVSKSHSAQMLRLNEKIEELKGVVEELQTDLARAKKGKPPLKSADGKP 2950
            NKEVAIICNHQRTVSKSHSAQM RLNEKI+ELK  +EEL+TDL+RAKKGKPP K ADGK 
Sbjct: 780  NKEVAIICNHQRTVSKSHSAQMSRLNEKIDELKTALEELKTDLSRAKKGKPPTKGADGKA 839

Query: 2951 KRNLNPDALERKIAQTTAKIEKMERDKETKEDLKTVALGTSKINYLDPRITVAWCKRHEV 3130
            KRNLNP+ALERKI QT AKIEKMERDKETKEDLKTVALGTSKINYLDPRITVAWCKRHEV
Sbjct: 840  KRNLNPEALERKITQTNAKIEKMERDKETKEDLKTVALGTSKINYLDPRITVAWCKRHEV 899

Query: 3131 PIEKIFNKSLLAKFAWAMDVDPGFRF 3208
            PIEKIFNKSLLAKFAW+MDVDP FRF
Sbjct: 900  PIEKIFNKSLLAKFAWSMDVDPSFRF 925


>dbj|BAG31375.1| topoisomerase I [Ophiorrhiza japonica]
          Length = 927

 Score = 1119 bits (2895), Expect = 0.0
 Identities = 591/928 (63%), Positives = 667/928 (71%), Gaps = 35/928 (3%)
 Frame = +2

Query: 530  MAVEACDKQKLXXXXXXXXXPLVFKRXXXXXXXXXXXXEAKKSLSQKHDRQLGRPAPDVR 709
            MAVEAC    L         P++FKR            E KK   QKH  Q      DVR
Sbjct: 1    MAVEACTPN-LMEDMEDDEGPVIFKRSNPASKQNQANSEKKKLSLQKHVGQSAVHTSDVR 59

Query: 710  SQNGQSTIVKKSKTVPLSKTPPVKYPLTSPKSSNTSGKALALKSPEVDSKPSTSVTDKSN 889
              NG+S+  +K +  P +KTPPVK PL+SPK+SN+S KA  + SP  +SKPS S T  + 
Sbjct: 60   PANGESSSAQKGRIQPSAKTPPVKSPLSSPKASNSSAKASPITSPGANSKPSASATSTAK 119

Query: 890  SVKHQIKD----EKLSTEATGEPNEDSQDSEDDKPLSARLPAGLSKVNSNHAKKSPNTST 1057
               H        E   +    + N +S+ S+D+KPLSAR     SK  SNHA K    S 
Sbjct: 120  QQNHHKSSAAFIEPKPSVPAAKANSNSESSDDEKPLSARTFGCSSKGKSNHANKEGGDSC 179

Query: 1058 LSQKRRIPIPEDSDDEIPLSSKFQVKSNAGESINRSSNSGERKPLLSKYDQNGSASTE-- 1231
              ++R I   EDS+DE PLS +F  KS+ GES ++S +S E+KPL +K  QNGS S +  
Sbjct: 180  SIRRRVIEESEDSEDEKPLSRRFTSKSSLGESTSKSYDSDEKKPLAAKVQQNGSVSRDGP 239

Query: 1232 -RKPSTNLKKRPGDGVKTTDESYLKKPKLSEAATPHKNKEASIKAEMR------------ 1372
              K ++   KRP   VK+ ++S +KKPKLS   T   NK+A++K E              
Sbjct: 240  MNKSASLSNKRPPGEVKSLNQSSVKKPKLSSPITSISNKQAAVKPEPEPKAEDDDDNIPL 299

Query: 1373 --------------EEDDEDHVPISHRMXXXXXXXXXXXXXXN-ITKPIXXXXXXXXXXX 1507
                          +++D+D+VPI+ R+                 +  +           
Sbjct: 300  SQRGKKSQAATSKPKDEDDDNVPIAQRIKKSPASVSKSSAPVKKASTVVSPSLKKVNKNS 359

Query: 1508 XXXXXXXXXXXXXXXXXXXGEGQKWTTLVHNGVIFPPPYKPHGVKMLYKGKPVDLTPEQE 1687
                               GEGQKWTTLVHNGVIFPPPY PHGVKMLYK +P+ LTPEQE
Sbjct: 360  KKVIKKTAYTKSSKVPPGSGEGQKWTTLVHNGVIFPPPYNPHGVKMLYKRQPITLTPEQE 419

Query: 1688 EVATMYAVMLETDYMNKPKFKENFMADWRKILGKNHTIQSLEHCDFTPIYEWHXXXXXXX 1867
            EVATM+AVML+TDYMNKP+FKENF +DW+K+LGKNHTIQ+LE CDF PIYEWH       
Sbjct: 420  EVATMFAVMLDTDYMNKPRFKENFFSDWKKMLGKNHTIQNLEDCDFGPIYEWHQQEKEKK 479

Query: 1868 XXXXXXXXXXXXXXXXXXXXXYMWAIVNGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKR 2047
                                 YMWAIV+GVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKR
Sbjct: 480  KQMTTEEKKALKEDKLQQEEKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKR 539

Query: 2048 IRPSDITINIGKDAPIPECPIPGESWKEIRHDNTVTWLAYWNDPINPKEFKYVFLAASST 2227
            IRP DITINIGKDAPIPECPIPGE WKE+R+DNTVTWLA+W DPIN KEFKYVFLAASST
Sbjct: 540  IRPRDITINIGKDAPIPECPIPGERWKEVRNDNTVTWLAFWIDPINQKEFKYVFLAASST 599

Query: 2228 LKGQSDKEKYEKARLLKDYILGIRAAYTKDFTS-KDPAKRQIAVATYLIDKLALRAGNEK 2404
            LKGQSDKEKYEKARLLKDYI GIRAAYTKDFT+ KDP K+QIAVATYLIDKLALRAGNEK
Sbjct: 600  LKGQSDKEKYEKARLLKDYIHGIRAAYTKDFTNNKDPMKKQIAVATYLIDKLALRAGNEK 659

Query: 2405 DDDEADTVGCCTLKVENVEPVPPNTLKFDFLGKDSIRYQNEVEVETAVFKAIQQFRSGKK 2584
            DDDEADTVGCCTLKVENVEPVPPN LKFDFLGKDSIRYQNEV+VE AVFKAIQQFRSGK+
Sbjct: 660  DDDEADTVGCCTLKVENVEPVPPNILKFDFLGKDSIRYQNEVQVEPAVFKAIQQFRSGKE 719

Query: 2585 GGDDLFDRLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSRETRGGDVAEKVVVYQ 2764
            G +DLFDRLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLS+ET+GG+VAEKVVVYQ
Sbjct: 720  GSEDLFDRLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSKETKGGEVAEKVVVYQ 779

Query: 2765 HANKEVAIICNHQRTVSKSHSAQMLRLNEKIEELKGVVEELQTDLARAKKGKPPLKSADG 2944
            HANKEVAIICNHQRTVSKSHSAQM RLNEKI+ELK  +EEL+TDL+R KKGKPP K ADG
Sbjct: 780  HANKEVAIICNHQRTVSKSHSAQMSRLNEKIDELKTAMEELKTDLSRVKKGKPPSKGADG 839

Query: 2945 KPKRNLNPDALERKIAQTTAKIEKMERDKETKEDLKTVALGTSKINYLDPRITVAWCKRH 3124
            KPKRNLNP+ALERK+AQ  AKIEKMERDKETKEDLKTVALGTSKINYLDPRITVAWCKRH
Sbjct: 840  KPKRNLNPEALERKMAQINAKIEKMERDKETKEDLKTVALGTSKINYLDPRITVAWCKRH 899

Query: 3125 EVPIEKIFNKSLLAKFAWAMDVDPGFRF 3208
            EVPIEKIFNKSLLAKFAW+MDVDP FRF
Sbjct: 900  EVPIEKIFNKSLLAKFAWSMDVDPSFRF 927


>dbj|BAK32958.1| topoisomerase I [Ophiorrhiza pedunculata]
          Length = 920

 Score = 1115 bits (2883), Expect = 0.0
 Identities = 590/919 (64%), Positives = 661/919 (71%), Gaps = 33/919 (3%)
 Frame = +2

Query: 530  MAVEACDKQKLXXXXXXXXXPLVFKRXXXXXXXXXXXXEAKKSLSQKHDRQLGRPAPDVR 709
            MAVEAC    L         P++FKR            E KK   QKH  Q      DVR
Sbjct: 1    MAVEACTTTNLMEDMEDDEGPVIFKRSNPASKQNQANSEKKKLSLQKHVGQSAVHTSDVR 60

Query: 710  SQNGQSTIVKKSKTVPLSKTPPVKYPLTSPKSSNTSGKALALKSPEVDSKPSTSVTDKSN 889
              NG+++  +K +  P +KTPPVK PL+SPK+SN+S KA  + SP  +SKPS S T  + 
Sbjct: 61   PANGENSSAQKGRIQPSAKTPPVKSPLSSPKASNSSAKASPITSPGANSKPSASATSTAK 120

Query: 890  SVKHQIKD----EKLSTEATGEPNEDSQDSEDDKPLSARLPAGLSKVNSNHAKKSPNTST 1057
               H        E   +    + N +S+ S+D+KPLSAR     SK  SNHA K    S 
Sbjct: 121  QQNHHKSSAAFIEPKPSVPAAKANSNSESSDDEKPLSARTFGCSSKGKSNHANKEGGDSC 180

Query: 1058 LSQKRRIPIPEDSDDEIPLSSKFQVKSNAGESINRSSNSGERKPLLSKYDQNGSASTE-- 1231
              ++  I   EDS+DE PLS +F  KS+ GES ++S +S E+KPL +K   NGSAS +  
Sbjct: 181  SIRRPVIEESEDSEDEKPLSRRFTSKSSLGESTSKSYDSDEKKPLAAKVQPNGSASRDSP 240

Query: 1232 -RKPSTNLKKRPGDGVKTTDESYLKKPKLSEAATPHKNKEASIKAEMREEDDE------- 1387
              K ++   KRP   VK+ ++S LKKPKLS   T   NK+A++K E + EDD+       
Sbjct: 241  MNKSASLSNKRPPGEVKSLNQSSLKKPKLSSPITSISNKQAAVKPEPKAEDDDDNIPLSQ 300

Query: 1388 -----------------DHVPISHRMXXXXXXXXXXXXXXN-ITKPIXXXXXXXXXXXXX 1513
                             D+VPIS R+                 +  +             
Sbjct: 301  RGKKSQTATSKPKDEDDDNVPISQRIKKSPASVSKSSAPVKKASTVVSPSLKKVNKKSKK 360

Query: 1514 XXXXXXXXXXXXXXXXXGEGQKWTTLVHNGVIFPPPYKPHGVKMLYKGKPVDLTPEQEEV 1693
                             GEGQKWTTLVHNGVIFPPPYKPHGVKMLYK +P+ LTPEQEEV
Sbjct: 361  VIKKTAYTKSSKVPPGSGEGQKWTTLVHNGVIFPPPYKPHGVKMLYKRQPITLTPEQEEV 420

Query: 1694 ATMYAVMLETDYMNKPKFKENFMADWRKILGKNHTIQSLEHCDFTPIYEWHXXXXXXXXX 1873
            ATM+AVML+TDYMNKP+FKENF +DW+K+LGKNHTIQ+LE CDF PIYEWH         
Sbjct: 421  ATMFAVMLDTDYMNKPRFKENFFSDWKKMLGKNHTIQNLEDCDFGPIYEWHQQEKEKKKQ 480

Query: 1874 XXXXXXXXXXXXXXXXXXXYMWAIVNGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIR 2053
                               YMWAIV+GVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIR
Sbjct: 481  MTTEEKKALKEEKLQQEEKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIR 540

Query: 2054 PSDITINIGKDAPIPECPIPGESWKEIRHDNTVTWLAYWNDPINPKEFKYVFLAASSTLK 2233
            P DITINIGKDAPIPECPIPGE WKE+R+DNTVTWLAYWNDPIN KEFKYVFLAASSTLK
Sbjct: 541  PRDITINIGKDAPIPECPIPGERWKEVRNDNTVTWLAYWNDPINQKEFKYVFLAASSTLK 600

Query: 2234 GQSDKEKYEKARLLKDYILGIRAAYTKDFTS-KDPAKRQIAVATYLIDKLALRAGNEKDD 2410
            GQSDKEKYEKARLLKDYI GIRAAYTKDFT+ KDP K+QIAVATYLIDKLALRAGNEKDD
Sbjct: 601  GQSDKEKYEKARLLKDYIHGIRAAYTKDFTNNKDPMKKQIAVATYLIDKLALRAGNEKDD 660

Query: 2411 DEADTVGCCTLKVENVEPVPPNTLKFDFLGKDSIRYQNEVEVETAVFKAIQQFRSGKKGG 2590
            DEADTVGCCTLKVENVEPVPPN LKFDFLGKDSIRYQNEV+VE AVFKAI QFRSGK+G 
Sbjct: 661  DEADTVGCCTLKVENVEPVPPNILKFDFLGKDSIRYQNEVQVEPAVFKAIHQFRSGKEGS 720

Query: 2591 DDLFDRLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSRETRGGDVAEKVVVYQHA 2770
            +DLFDRLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLS++T GG+VAEKVVVYQHA
Sbjct: 721  EDLFDRLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSKKTNGGEVAEKVVVYQHA 780

Query: 2771 NKEVAIICNHQRTVSKSHSAQMLRLNEKIEELKGVVEELQTDLARAKKGKPPLKSADGKP 2950
            NKEVAIICNHQRTVSKSHSAQM RLNEKI+ELK  +EEL+TDL+RAKKGKP  K ADGKP
Sbjct: 781  NKEVAIICNHQRTVSKSHSAQMSRLNEKIDELKTALEELKTDLSRAKKGKPLSKGADGKP 840

Query: 2951 KRNLNPDALERKIAQTTAKIEKMERDKETKEDLKTVALGTSKINYLDPRITVAWCKRHEV 3130
            KRNLNP+ALERKIAQT AKIEKMERDKETKEDLKTVALGTSKINYLDPRITVAWCKRHEV
Sbjct: 841  KRNLNPEALERKIAQTNAKIEKMERDKETKEDLKTVALGTSKINYLDPRITVAWCKRHEV 900

Query: 3131 PIEKIFNKSLLAKFAWAMD 3187
            PIEKIFNKSLLAKFAWAM+
Sbjct: 901  PIEKIFNKSLLAKFAWAMN 919


>dbj|BAK32962.1| topoisomerase I [Ophiorrhiza trichocarpon var. glabra]
          Length = 920

 Score = 1112 bits (2877), Expect = 0.0
 Identities = 589/919 (64%), Positives = 661/919 (71%), Gaps = 33/919 (3%)
 Frame = +2

Query: 530  MAVEACDKQKLXXXXXXXXXPLVFKRXXXXXXXXXXXXEAKKSLSQKHDRQLGRPAPDVR 709
            MAVEAC    L         P++FKR            E KK   Q+H  Q      DVR
Sbjct: 1    MAVEACTTTNLMEDMEDDEGPVIFKRSNPASKQNQANSEKKKLSLQRHVGQSAVHTSDVR 60

Query: 710  SQNGQSTIVKKSKTVPLSKTPPVKYPLTSPKSSNTSGKALALKSPEVDSKPSTSVTDKSN 889
              NG+++  +K +  P +KTPPVK PL+SPK+SN+S KA  + S   +SKPS S T  + 
Sbjct: 61   PANGENSSAQKGRIQPSAKTPPVKSPLSSPKASNSSAKASPITSAGANSKPSASATSTAK 120

Query: 890  SVKHQIKD----EKLSTEATGEPNEDSQDSEDDKPLSARLPAGLSKVNSNHAKKSPNTST 1057
               H        E   +    + N +S+ S+D+KPLSAR     SK  SNHA K    S 
Sbjct: 121  QQNHHKSSAAFIEPKPSVPAAKANSNSESSDDEKPLSARTFGCSSKGKSNHANKEGGDSC 180

Query: 1058 LSQKRRIPIPEDSDDEIPLSSKFQVKSNAGESINRSSNSGERKPLLSKYDQNGSASTE-- 1231
              ++  I   EDS+DE PLS +F  KS+ GES ++S +S E+KPL +K   NGSAS +  
Sbjct: 181  SIRRPVIEESEDSEDEKPLSRRFTSKSSLGESTSKSYDSDEKKPLAAKVQPNGSASRDSP 240

Query: 1232 -RKPSTNLKKRPGDGVKTTDESYLKKPKLSEAATPHKNKEASIKAEMREEDDE------- 1387
              K ++   KRP   VK+ ++S LKKPKLS   T   NK+A++K E + EDD+       
Sbjct: 241  MNKSASLSNKRPPGEVKSLNQSSLKKPKLSSPITSISNKQAAVKPEPKAEDDDDNIPLSQ 300

Query: 1388 -----------------DHVPISHRMXXXXXXXXXXXXXXN-ITKPIXXXXXXXXXXXXX 1513
                             D+VPIS R+                 +  +             
Sbjct: 301  RGKKSQTATSKPKDEDDDNVPISQRIKKSPASVSKSSAPVKKASTVVSPSLKKVNKKSKK 360

Query: 1514 XXXXXXXXXXXXXXXXXGEGQKWTTLVHNGVIFPPPYKPHGVKMLYKGKPVDLTPEQEEV 1693
                             GEGQKWTTLVHNGVIFPPPYKPHGVKMLYK +P+ LTPEQEEV
Sbjct: 361  VIKKTAYTKSSKVPPGSGEGQKWTTLVHNGVIFPPPYKPHGVKMLYKRQPITLTPEQEEV 420

Query: 1694 ATMYAVMLETDYMNKPKFKENFMADWRKILGKNHTIQSLEHCDFTPIYEWHXXXXXXXXX 1873
            ATM+AVML+TDYMNKP+FKENF +DW+K+LGKNHTIQ+LE CDF PIYEWH         
Sbjct: 421  ATMFAVMLDTDYMNKPRFKENFFSDWKKMLGKNHTIQNLEDCDFGPIYEWHQQEKEKKKQ 480

Query: 1874 XXXXXXXXXXXXXXXXXXXYMWAIVNGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIR 2053
                               YMWAIV+GVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIR
Sbjct: 481  MTTEEKKALKEEKLQQEEKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIR 540

Query: 2054 PSDITINIGKDAPIPECPIPGESWKEIRHDNTVTWLAYWNDPINPKEFKYVFLAASSTLK 2233
            P DITINIGKDAPIPECPIPGE WKE+R+DNTVTWLAYWNDPIN KEFKYVFLAASSTLK
Sbjct: 541  PRDITINIGKDAPIPECPIPGERWKEVRNDNTVTWLAYWNDPINQKEFKYVFLAASSTLK 600

Query: 2234 GQSDKEKYEKARLLKDYILGIRAAYTKDFTS-KDPAKRQIAVATYLIDKLALRAGNEKDD 2410
            GQSDKEKYEKARLLKDYI GIRAAYTKDFT+ KDP K+QIAVATYLIDKLALRAGNEKDD
Sbjct: 601  GQSDKEKYEKARLLKDYIHGIRAAYTKDFTNNKDPMKKQIAVATYLIDKLALRAGNEKDD 660

Query: 2411 DEADTVGCCTLKVENVEPVPPNTLKFDFLGKDSIRYQNEVEVETAVFKAIQQFRSGKKGG 2590
            DEADTVGCCTLKVENVEPVPPN LKFDFLGKDSIRYQNEV+VE AVFKAIQQFRSGK+G 
Sbjct: 661  DEADTVGCCTLKVENVEPVPPNILKFDFLGKDSIRYQNEVQVEPAVFKAIQQFRSGKEGS 720

Query: 2591 DDLFDRLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSRETRGGDVAEKVVVYQHA 2770
            +DLFDRLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLS++T GG+VAEKVVVYQHA
Sbjct: 721  EDLFDRLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSKKTNGGEVAEKVVVYQHA 780

Query: 2771 NKEVAIICNHQRTVSKSHSAQMLRLNEKIEELKGVVEELQTDLARAKKGKPPLKSADGKP 2950
            NKEVAIICNHQRTVSKSHSAQM RLNEKI+ELK  +EEL+TDL+RAKKGKP  K ADGKP
Sbjct: 781  NKEVAIICNHQRTVSKSHSAQMSRLNEKIDELKTALEELKTDLSRAKKGKPLSKGADGKP 840

Query: 2951 KRNLNPDALERKIAQTTAKIEKMERDKETKEDLKTVALGTSKINYLDPRITVAWCKRHEV 3130
            KRNLNP+ALERKIAQT AKIEKMERDKETKEDLKTVALGTSKINYLDPRITVAWCKRHEV
Sbjct: 841  KRNLNPEALERKIAQTNAKIEKMERDKETKEDLKTVALGTSKINYLDPRITVAWCKRHEV 900

Query: 3131 PIEKIFNKSLLAKFAWAMD 3187
            PIEKIFNKSLLAKFAWAM+
Sbjct: 901  PIEKIFNKSLLAKFAWAMN 919


>ref|XP_006364175.2| PREDICTED: DNA topoisomerase 1-like [Solanum tuberosum]
          Length = 905

 Score = 1104 bits (2856), Expect = 0.0
 Identities = 579/918 (63%), Positives = 661/918 (72%), Gaps = 25/918 (2%)
 Frame = +2

Query: 530  MAVEACDKQKLXXXXXXXXX-PLVFKRXXXXXXXXXXXXEAKKSLSQKHDRQLGRPAPDV 706
            MAVEA  K  L          PLVFKR                S SQK D + GR  PDV
Sbjct: 1    MAVEAFAKTNLMEDIDDDDDMPLVFKRSSTTSKQ-----NQSNSSSQKQDGRSGRQVPDV 55

Query: 707  RSQNGQSTIVKKSKTVPLSKTPPVKYPLTSPKSSNTSGKAL------------------- 829
            RS NGQS+   K KT   SK  P   PLTSPK++  S +                     
Sbjct: 56   RSPNGQSSSTHKVKTAASSKASPAVSPLTSPKAAPLSSRTSPAPNFRTSPAPNSRTPPAP 115

Query: 830  -ALKSPEVDSKPSTSVTDKSNSVKHQI----KDEKLSTEATGEPNEDSQDSEDDKPLSAR 994
             +  SP  +S+PS+S  +++ +V  Q     K+ K + E   EPN++++DSEDDKPLSAR
Sbjct: 116  NSRTSPAPNSRPSSSAGNQAKNVNQQSNIAPKESKQAIEPKSEPNDEAEDSEDDKPLSAR 175

Query: 995  LPAGLSKVNSNHAKKSPNTSTLSQKRRIPIPEDSDDEIPLSSKFQVKSNAGESINRSSNS 1174
            +P+GLSK NS HA     TST  QK R P  EDSDDEIPL+S+FQ+KS+AG S ++ S+S
Sbjct: 176  VPSGLSKSNSIHANNVLGTSTSVQKSRPPKKEDSDDEIPLASRFQMKSSAGASTSKFSSS 235

Query: 1175 GERKPLLSKYDQNGSASTERKPSTNLKKRPGDGVKTTDESYLKKPKLSEAATPHKNKEAS 1354
             E KP   K  QNG  S     +T L KRP   VK+  ++ +KKP+LS+A+TP  +K+ S
Sbjct: 236  EEVKP---KIRQNGLPS-----ATVLSKRPPGEVKSAAQASVKKPRLSDASTPVSSKQPS 287

Query: 1355 IKAEMREEDDEDHVPISHRMXXXXXXXXXXXXXXNITKPIXXXXXXXXXXXXXXXXXXXX 1534
            +K E + EDD+D VP+S R+              +  K                      
Sbjct: 288  VKTEKKTEDDDDEVPLSQRIKKAVASASASASKVSSVKKATKVVSSSMKKTKKKLKKPKY 347

Query: 1535 XXXXXXXXXXGEGQKWTTLVHNGVIFPPPYKPHGVKMLYKGKPVDLTPEQEEVATMYAVM 1714
                      G+GQKWTTL HNGVIFPPPYKPHGVKMLYKGKPVDLTPEQEEVATMYAVM
Sbjct: 348  SKSSKLQPSSGDGQKWTTLEHNGVIFPPPYKPHGVKMLYKGKPVDLTPEQEEVATMYAVM 407

Query: 1715 LETDYMNKPKFKENFMADWRKILGKNHTIQSLEHCDFTPIYEWHXXXXXXXXXXXXXXXX 1894
            L+T+Y+ K +FKENFM DWRKILGKNH IQ LE C+FTPIYEWH                
Sbjct: 408  LDTEYLTKQQFKENFMNDWRKILGKNHVIQKLEECNFTPIYEWHQSEKEKKKQMSSEEKK 467

Query: 1895 XXXXXXXXXXXXYMWAIVNGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIRPSDITIN 2074
                        YMWAIV+GVKEKVGNFRVEPPGLFRGRGEHPKMGKLK+RIRP+DITIN
Sbjct: 468  ALREEKLKQEEKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKRRIRPNDITIN 527

Query: 2075 IGKDAPIPECPIPGESWKEIRHDNTVTWLAYWNDPINPKEFKYVFLAASSTLKGQSDKEK 2254
            IGK  P+PECPIPG+ WKE+RHDNTVTWLA+WNDPINP+EFKYVFLAASS+LKGQSDKEK
Sbjct: 528  IGKGVPVPECPIPGQRWKEVRHDNTVTWLAFWNDPINPREFKYVFLAASSSLKGQSDKEK 587

Query: 2255 YEKARLLKDYILGIRAAYTKDFTSKDPAKRQIAVATYLIDKLALRAGNEKDDDEADTVGC 2434
            YEKAR LKDYI GIR+AYTKDFTSKDP KRQIAVATYLIDKLALRAGNEKDDDEADTVGC
Sbjct: 588  YEKARRLKDYIEGIRSAYTKDFTSKDPVKRQIAVATYLIDKLALRAGNEKDDDEADTVGC 647

Query: 2435 CTLKVENVEPVPPNTLKFDFLGKDSIRYQNEVEVETAVFKAIQQFRSGKKGGDDLFDRLD 2614
            CTLKVENVEPVPPN LKFDFLGKDSIRYQNEV V   VFKAIQQFRSGKKGGDDLFD+LD
Sbjct: 648  CTLKVENVEPVPPNILKFDFLGKDSIRYQNEVAVYEPVFKAIQQFRSGKKGGDDLFDKLD 707

Query: 2615 TSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSRETRGGDVAEKVVVYQHANKEVAIIC 2794
            TSKLNAHLKELMPGLTAKVFRTYNAS TL+  L++ T+GG++A+KV VY  ANKEVAIIC
Sbjct: 708  TSKLNAHLKELMPGLTAKVFRTYNASFTLEQQLTKLTQGGELADKVAVYNVANKEVAIIC 767

Query: 2795 NHQRTVSKSHSAQMLRLNEKIEELKGVVEELQTDLARAKKGKPPLKSADGKPKRNLNPDA 2974
            NHQRTVSKSHS Q+ RLNEKI+ELK ++EE + DLARAKKGKPP+K ADGK KRNL P+A
Sbjct: 768  NHQRTVSKSHSVQISRLNEKIDELKAILEEFKVDLARAKKGKPPVKGADGKAKRNLTPEA 827

Query: 2975 LERKIAQTTAKIEKMERDKETKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNK 3154
            L++KI QT  KI+ +ER  ETKE+LKTVALGTSKINYLDPRITVAWCKRHEVPIEK+FNK
Sbjct: 828  LQKKIDQTNVKIDNIERQIETKEELKTVALGTSKINYLDPRITVAWCKRHEVPIEKMFNK 887

Query: 3155 SLLAKFAWAMDVDPGFRF 3208
            SLLAKFAWAMDV+P F F
Sbjct: 888  SLLAKFAWAMDVEPSFTF 905


>dbj|BAK32961.1| topoisomerase I [Ophiorrhiza ridleyana]
          Length = 926

 Score = 1099 bits (2842), Expect = 0.0
 Identities = 581/927 (62%), Positives = 660/927 (71%), Gaps = 34/927 (3%)
 Frame = +2

Query: 530  MAVEACDKQKLXXXXXXXXXPLVFKRXXXXXXXXXXXXEAKKSLSQKHDRQLGRPAPDVR 709
            MAVEAC    L         P++FKR            E KK   QKH  Q      DVR
Sbjct: 1    MAVEACTTTNLMEDMEDDEGPVIFKRSNPTSKQNQANAEKKKLSLQKHVGQSAVHTSDVR 60

Query: 710  SQNGQSTIVKKSKTVPLSKTPPVKYPLTSPKSSNTSGKALALKSPEVDSKPSTSVTDKSN 889
              NG+S+  +K +  P ++TPPVK PL+SPK+SN+S KA  + SP  +SK S S T  + 
Sbjct: 61   PANGESSSAQKGRIQPSAETPPVKSPLSSPKASNSSAKASPITSPGANSKLSASATSTAK 120

Query: 890  SVKHQIKD----EKLSTEATGEPNEDSQDSEDDKPLSARLPAGLSKVNSNHAKKSPNTST 1057
               H        E   +    + N +S+ S+D+KPL AR     S   SNHA K    S 
Sbjct: 121  QQNHHKSSAAFIEPKPSVPAAKANSNSESSDDEKPLIARTSGCSSMGKSNHANKEGGDSC 180

Query: 1058 LSQKRRIPIPEDSDDEIPLSSKFQVKSNAGESINRSSNSGERKPLLSKYDQNGSASTE-- 1231
              ++  I   EDS+DE PLS +F  KS+ GES ++S +S E+KPL +K  QNGSAS E  
Sbjct: 181  SIRRPVIEESEDSEDEKPLSRRFPSKSSLGESTSKSYDSDEKKPLAAKVQQNGSASPEGP 240

Query: 1232 --RKPSTNLKKRPGDGVKTTDESYLKKPKLSEAATPHKNKEASIKAEMREEDDED----- 1390
              +  S + K+ PG+ VK+ ++S LKKPKLS   T   NK+A++K E + EDD+D     
Sbjct: 241  MNKSASLSNKRAPGE-VKSLNQSSLKKPKLSSPITSISNKQAAVKPEPKAEDDDDNIPLS 299

Query: 1391 -------------------HVPISHRMXXXXXXXXXXXXXXN-ITKPIXXXXXXXXXXXX 1510
                               H PIS R+                 +  +            
Sbjct: 300  QRGKKSQTAASKPKDEDDDHAPISQRIKKSPVSVSKSSAPVKKASTVVSTSLKKVNKKSK 359

Query: 1511 XXXXXXXXXXXXXXXXXXGEGQKWTTLVHNGVIFPPPYKPHGVKMLYKGKPVDLTPEQEE 1690
                              GEGQKWTTLVHNGV+FPPPYKPHGVKMLYK +P+ LTPEQEE
Sbjct: 360  KVIRKTAYTKSSKVPPGSGEGQKWTTLVHNGVMFPPPYKPHGVKMLYKRQPLTLTPEQEE 419

Query: 1691 VATMYAVMLETDYMNKPKFKENFMADWRKILGKNHTIQSLEHCDFTPIYEWHXXXXXXXX 1870
            VATM+AVML+TDYMNKP+FKENF +DW+KILGKNHTIQ+LE CDF PIYEWH        
Sbjct: 420  VATMFAVMLDTDYMNKPRFKENFFSDWKKILGKNHTIQNLEDCDFGPIYEWHQQEKEKKK 479

Query: 1871 XXXXXXXXXXXXXXXXXXXXYMWAIVNGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRI 2050
                                YMWAIV+GVKEKVGNFRVEPPGLFRGRGEHPK+GKLKKRI
Sbjct: 480  QMTTEEKKALKEERLQQEEKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKVGKLKKRI 539

Query: 2051 RPSDITINIGKDAPIPECPIPGESWKEIRHDNTVTWLAYWNDPINPKEFKYVFLAASSTL 2230
            RP DITINIGKDAPIPECPIPGE WKE+R+DNTVTWLAYWNDP+N KE KYVFLAASSTL
Sbjct: 540  RPRDITINIGKDAPIPECPIPGERWKEVRNDNTVTWLAYWNDPVNIKECKYVFLAASSTL 599

Query: 2231 KGQSDKEKYEKARLLKDYILGIRAAYTKDFTS-KDPAKRQIAVATYLIDKLALRAGNEKD 2407
            KGQS KEKYEKAR+LKDYI GIRAAYTK FT+ KDP K+QIAVATYLIDKLALRAGNEKD
Sbjct: 600  KGQSVKEKYEKARVLKDYIHGIRAAYTKGFTNNKDPMKKQIAVATYLIDKLALRAGNEKD 659

Query: 2408 DDEADTVGCCTLKVENVEPVPPNTLKFDFLGKDSIRYQNEVEVETAVFKAIQQFRSGKKG 2587
            DDEADTVGCCTLKVENVEPVPPN LK DF+GKDSIRYQNEV+VE AVFKAIQQFRSGK+G
Sbjct: 660  DDEADTVGCCTLKVENVEPVPPNILKIDFIGKDSIRYQNEVQVEPAVFKAIQQFRSGKEG 719

Query: 2588 GDDLFDRLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSRETRGGDVAEKVVVYQH 2767
             +DLFDRLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLS+ET+GG +AEKV VYQH
Sbjct: 720  SEDLFDRLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSKETKGGKIAEKVAVYQH 779

Query: 2768 ANKEVAIICNHQRTVSKSHSAQMLRLNEKIEELKGVVEELQTDLARAKKGKPPLKSADGK 2947
            ANKEVAIICNHQRTVSKSHSAQM RLNEKI+ELK  +EEL+TDL+RAKKGKPP K ADG+
Sbjct: 780  ANKEVAIICNHQRTVSKSHSAQMSRLNEKIDELKTALEELKTDLSRAKKGKPPSKDADGE 839

Query: 2948 PKRNLNPDALERKIAQTTAKIEKMERDKETKEDLKTVALGTSKINYLDPRITVAWCKRHE 3127
            PKRNLNP++LERKIAQT AKIEKMERDK+TKEDLK VAL TSKI+YLDPRITVAWCKR E
Sbjct: 840  PKRNLNPESLERKIAQTNAKIEKMERDKKTKEDLKAVALSTSKISYLDPRITVAWCKRQE 899

Query: 3128 VPIEKIFNKSLLAKFAWAMDVDPGFRF 3208
            VPIEK+FNKSLLAKFAWAMDVDP FRF
Sbjct: 900  VPIEKMFNKSLLAKFAWAMDVDPSFRF 926


>dbj|BAG31373.1| topoisomerase I [Ophiorrhiza pumila]
          Length = 926

 Score = 1098 bits (2841), Expect = 0.0
 Identities = 581/927 (62%), Positives = 660/927 (71%), Gaps = 34/927 (3%)
 Frame = +2

Query: 530  MAVEACDKQKLXXXXXXXXXPLVFKRXXXXXXXXXXXXEAKKSLSQKHDRQLGRPAPDVR 709
            MAVEAC    L         P++FKR            E KK   QKH  Q      DVR
Sbjct: 1    MAVEACTTPNLMEDMEDDEGPVIFKRSNPASKQNQANSEKKKLSLQKHVGQSAVHTSDVR 60

Query: 710  SQNGQSTIVKKSKTVPLSKTPPVKYPLTSPKSSNTSGKALALKSPEVDSKPSTSVTDKSN 889
              NG+S+  +K +  P ++TPPVK PL+SPK+SN+S KA  + SP  +SK S S T  + 
Sbjct: 61   PANGESSSAQKGRIQPSAETPPVKSPLSSPKASNSSAKASPITSPGANSKLSASATSTAK 120

Query: 890  SVKHQIKD----EKLSTEATGEPNEDSQDSEDDKPLSARLPAGLSKVNSNHAKKSPNTST 1057
               H        E   +    + N +S+ S+D+KPL AR     SK  SNHA K    S 
Sbjct: 121  QQNHHKSSAAFIEPKPSVPAAKANSNSESSDDEKPLIARTSGCSSKGKSNHANKEGGDSC 180

Query: 1058 LSQKRRIPIPEDSDDEIPLSSKFQVKSNAGESINRSSNSGERKPLLSKYDQNGSASTE-- 1231
              ++  I   EDS+DE PLS +F  KS+ GES ++S +S E+KPL +K  QNGSAS +  
Sbjct: 181  SIRRPVIEESEDSEDEKPLSRRFPSKSSLGESTSKSHDSDEKKPLAAKVQQNGSASRDGP 240

Query: 1232 --RKPSTNLKKRPGDGVKTTDESYLKKPKLSEAATPHKNKEASIKAEMREEDDE------ 1387
              +  S + K+ PG+ VK+ ++S LKKPKLS   T   NK+A++K E + EDD+      
Sbjct: 241  MNKSASLSNKRAPGE-VKSLNQSSLKKPKLSSTITSISNKQAAVKPEPKAEDDDDNIPLS 299

Query: 1388 ------------------DHVPISHRMXXXXXXXXXXXXXXN-ITKPIXXXXXXXXXXXX 1510
                              D+ PIS R+                 +  +            
Sbjct: 300  QRGKKSQTAASKPKDEDDDNAPISQRIKKSPASVSKSSAPVKKASTVVSPSLKKVNKKSK 359

Query: 1511 XXXXXXXXXXXXXXXXXXGEGQKWTTLVHNGVIFPPPYKPHGVKMLYKGKPVDLTPEQEE 1690
                              GEGQKWTTLVHNGV+FPPPYKPHGVKMLYK +P+ LTPEQEE
Sbjct: 360  KVIKKTAYTKSSKVPPGSGEGQKWTTLVHNGVMFPPPYKPHGVKMLYKRQPLTLTPEQEE 419

Query: 1691 VATMYAVMLETDYMNKPKFKENFMADWRKILGKNHTIQSLEHCDFTPIYEWHXXXXXXXX 1870
            VATM+A ML+TDYMNKP+FKENF +DW+KILGKNHTIQ+LE CDF PIYEWH        
Sbjct: 420  VATMFAAMLDTDYMNKPRFKENFFSDWKKILGKNHTIQNLEDCDFGPIYEWHQQEKEKKK 479

Query: 1871 XXXXXXXXXXXXXXXXXXXXYMWAIVNGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRI 2050
                                YMWAIV+GVKEKVGNFRVEPPGLFRGRGEHPK+GKLKKRI
Sbjct: 480  QMTTEEKKALKEERLQLEEKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKVGKLKKRI 539

Query: 2051 RPSDITINIGKDAPIPECPIPGESWKEIRHDNTVTWLAYWNDPINPKEFKYVFLAASSTL 2230
            RP DITINIGKDAPIPECPIPGE WKE+R+DNTVTWLAYWNDP+N KE KYVFLAASSTL
Sbjct: 540  RPRDITINIGKDAPIPECPIPGERWKEVRNDNTVTWLAYWNDPVNLKECKYVFLAASSTL 599

Query: 2231 KGQSDKEKYEKARLLKDYILGIRAAYTKDFTS-KDPAKRQIAVATYLIDKLALRAGNEKD 2407
            KGQSDKEKYEKARLLKDYI GIRAAYTKDFT+ KDP K+Q+AVATYLIDKLALRAGNEKD
Sbjct: 600  KGQSDKEKYEKARLLKDYIHGIRAAYTKDFTNNKDPMKKQVAVATYLIDKLALRAGNEKD 659

Query: 2408 DDEADTVGCCTLKVENVEPVPPNTLKFDFLGKDSIRYQNEVEVETAVFKAIQQFRSGKKG 2587
            DDEADTVGCCTLKVENVEPVPPN LK DF+GKDSIRYQNEV+VE AVFKAIQQFRSGK+G
Sbjct: 660  DDEADTVGCCTLKVENVEPVPPNILKIDFIGKDSIRYQNEVQVEPAVFKAIQQFRSGKEG 719

Query: 2588 GDDLFDRLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSRETRGGDVAEKVVVYQH 2767
             +DLFDRLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLS+ET+GG VAEKV VYQ 
Sbjct: 720  SEDLFDRLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSKETKGGKVAEKVGVYQR 779

Query: 2768 ANKEVAIICNHQRTVSKSHSAQMLRLNEKIEELKGVVEELQTDLARAKKGKPPLKSADGK 2947
            ANKEVAIICNHQRTVSKSHSAQM RLNEKI+ELK  +EEL+TDL+RAKKGKPP K  DG+
Sbjct: 780  ANKEVAIICNHQRTVSKSHSAQMSRLNEKIDELKTALEELKTDLSRAKKGKPPSKGDDGE 839

Query: 2948 PKRNLNPDALERKIAQTTAKIEKMERDKETKEDLKTVALGTSKINYLDPRITVAWCKRHE 3127
            PKRNLNP+ALERKIAQT AKIEKMERDK+TKEDLK VAL TSKI+YLDPRITVAWCKR E
Sbjct: 840  PKRNLNPEALERKIAQTNAKIEKMERDKKTKEDLKAVALSTSKISYLDPRITVAWCKRQE 899

Query: 3128 VPIEKIFNKSLLAKFAWAMDVDPGFRF 3208
            VPIEK+FNKSLLAKFAWAMDVDP FRF
Sbjct: 900  VPIEKMFNKSLLAKFAWAMDVDPSFRF 926


>dbj|BAK32956.1| topoisomerase I [Ophiorrhiza fucosa]
          Length = 926

 Score = 1097 bits (2836), Expect = 0.0
 Identities = 580/927 (62%), Positives = 659/927 (71%), Gaps = 34/927 (3%)
 Frame = +2

Query: 530  MAVEACDKQKLXXXXXXXXXPLVFKRXXXXXXXXXXXXEAKKSLSQKHDRQLGRPAPDVR 709
            MAVEAC    L         P++FKR            E KK   QKH  Q      DVR
Sbjct: 1    MAVEACTTTNLMEDMEDDEGPVIFKRSNPASKQNQANSEKKKLSLQKHVGQSAVHTSDVR 60

Query: 710  SQNGQSTIVKKSKTVPLSKTPPVKYPLTSPKSSNTSGKALALKSPEVDSKPSTSVTDKSN 889
              NG+S+  +K +  P ++TPPVK PL+SPK+SN+S KA  + SP  +SK S S T  + 
Sbjct: 61   PANGESSSAQKGRIQPSAETPPVKSPLSSPKASNSSAKASPITSPGANSKLSASATSTAK 120

Query: 890  SVKHQIKD----EKLSTEATGEPNEDSQDSEDDKPLSARLPAGLSKVNSNHAKKSPNTST 1057
               H        E   +    + N +S+ S+D+KPL AR     SK  SNHA K    S 
Sbjct: 121  QQNHHKSSAAFIEPKPSVPPAKANSNSESSDDEKPLIARTSGCSSKGKSNHANKEGGDSC 180

Query: 1058 LSQKRRIPIPEDSDDEIPLSSKFQVKSNAGESINRSSNSGERKPLLSKYDQNGSASTE-- 1231
              ++  +   EDS+DE PLS +F  KS+ GES ++S +S E+KPL +K  QNGSAS +  
Sbjct: 181  SIRRPVVEESEDSEDEKPLSRRFPSKSSLGESTSKSYDSDEKKPLAAKVQQNGSASRDGP 240

Query: 1232 --RKPSTNLKKRPGDGVKTTDESYLKKPKLSEAATPHKNKEASIKAEMREEDDE------ 1387
              +  S + K+ PG+ VK+ ++S LKKPKLS   T   NK+A++K E + EDD+      
Sbjct: 241  MNKSASLSNKRAPGE-VKSLNQSSLKKPKLSSPITSISNKQAAVKPEPKAEDDDDNIPLS 299

Query: 1388 ------------------DHVPISHRMXXXXXXXXXXXXXXN-ITKPIXXXXXXXXXXXX 1510
                              D+ PIS R+                 +  +            
Sbjct: 300  QRGKKSQTAASKPKDEDDDNAPISQRIKKSPASVSKSSAPVKKASTVVSPSLKKVNKKSK 359

Query: 1511 XXXXXXXXXXXXXXXXXXGEGQKWTTLVHNGVIFPPPYKPHGVKMLYKGKPVDLTPEQEE 1690
                              GEGQKWTTLVHNGV+FPPPYKPHGVKMLYK +P+ LTPEQEE
Sbjct: 360  KVIKKTAYTKSSKVPPGSGEGQKWTTLVHNGVMFPPPYKPHGVKMLYKRQPLTLTPEQEE 419

Query: 1691 VATMYAVMLETDYMNKPKFKENFMADWRKILGKNHTIQSLEHCDFTPIYEWHXXXXXXXX 1870
            VATM+A ML+TDYMNKP+FKENF +DW+KILGKNHTIQ+LE CDF PIYEWH        
Sbjct: 420  VATMFAAMLDTDYMNKPRFKENFFSDWKKILGKNHTIQNLEDCDFGPIYEWHQQEREKKK 479

Query: 1871 XXXXXXXXXXXXXXXXXXXXYMWAIVNGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRI 2050
                                YMWAIV+GVKEKVGNFRVEPPGLFRGRGEHPK+GKLKKRI
Sbjct: 480  QMTTEEKKALKDERLQLEEKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKVGKLKKRI 539

Query: 2051 RPSDITINIGKDAPIPECPIPGESWKEIRHDNTVTWLAYWNDPINPKEFKYVFLAASSTL 2230
             P DITINIGKDAPIPECPIPGE WKE+R+DNTVTWLAYWNDP+N KE KYVFLA SSTL
Sbjct: 540  HPRDITINIGKDAPIPECPIPGERWKEVRNDNTVTWLAYWNDPVNLKECKYVFLAPSSTL 599

Query: 2231 KGQSDKEKYEKARLLKDYILGIRAAYTKDFTS-KDPAKRQIAVATYLIDKLALRAGNEKD 2407
            KGQSDKEKYEKARLLKDYI GIRAAYTKDFT+ KDP K+QIAVATYLIDKLALRAGNEKD
Sbjct: 600  KGQSDKEKYEKARLLKDYIHGIRAAYTKDFTNNKDPMKKQIAVATYLIDKLALRAGNEKD 659

Query: 2408 DDEADTVGCCTLKVENVEPVPPNTLKFDFLGKDSIRYQNEVEVETAVFKAIQQFRSGKKG 2587
            DDEADTVGCCTLKVENVEPVPPN LK DF+GKDSIRYQNEV+VE AVFKAIQQFRSGK+G
Sbjct: 660  DDEADTVGCCTLKVENVEPVPPNILKIDFIGKDSIRYQNEVQVEPAVFKAIQQFRSGKEG 719

Query: 2588 GDDLFDRLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSRETRGGDVAEKVVVYQH 2767
             +DLFDRLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLS+ET+GG VAEKV VYQH
Sbjct: 720  SEDLFDRLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSKETKGGKVAEKVGVYQH 779

Query: 2768 ANKEVAIICNHQRTVSKSHSAQMLRLNEKIEELKGVVEELQTDLARAKKGKPPLKSADGK 2947
            ANKEVAIICNHQRTVSKSHSAQM RLNEKI+ELK  +EEL+TDL+RAKKGKPP K  DG+
Sbjct: 780  ANKEVAIICNHQRTVSKSHSAQMSRLNEKIDELKTALEELKTDLSRAKKGKPPSKGDDGE 839

Query: 2948 PKRNLNPDALERKIAQTTAKIEKMERDKETKEDLKTVALGTSKINYLDPRITVAWCKRHE 3127
            PKRNLNP+ALERKIAQT AKIEKMERDK+TKEDLK VAL TSKI+YLDPRITVAWCKR E
Sbjct: 840  PKRNLNPEALERKIAQTNAKIEKMERDKKTKEDLKAVALSTSKISYLDPRITVAWCKRQE 899

Query: 3128 VPIEKIFNKSLLAKFAWAMDVDPGFRF 3208
            VPIEK+FNKSLLAKFAWAMDVDP FRF
Sbjct: 900  VPIEKMFNKSLLAKFAWAMDVDPSFRF 926


>dbj|BAG31374.1| topoisomerase I [Ophiorrhiza liukiuensis]
          Length = 926

 Score = 1096 bits (2834), Expect = 0.0
 Identities = 581/926 (62%), Positives = 658/926 (71%), Gaps = 33/926 (3%)
 Frame = +2

Query: 530  MAVEACDKQKLXXXXXXXXXPLVFKRXXXXXXXXXXXXEAKKSLSQKHDRQLGRPAPDVR 709
            MAVEAC    L         P++FKR            E KK   QKH  Q      DVR
Sbjct: 1    MAVEACTTPNLMEDMEDDEGPVIFKRSNPASKQNQANSEKKKLSLQKHVGQSAVHTSDVR 60

Query: 710  SQNGQSTIVKKSKTVPLSKTPPVKYPLTSPKSSNTSGKALALKSPEVDSKPSTSVTDKSN 889
              NG+S+  +K +  P ++TPPVK PL+SPK+SN+S KA  + SP  +SK S S T  + 
Sbjct: 61   PANGESSSAQKGRIQPSAETPPVKSPLSSPKASNSSAKASPITSPGANSKLSASATSTAK 120

Query: 890  SVKHQIKD----EKLSTEATGEPNEDSQDSEDDKPLSARLPAGLSKVNSNHAKKSPNTST 1057
               H        E   +    + N +S+ S+D+KPL AR     SK  SNHA K    S 
Sbjct: 121  QQNHHKSSAAFIEPKPSVPAAKANSNSESSDDEKPLIARTSGCSSKGKSNHANKEGGDSC 180

Query: 1058 LSQKRRIPIPEDSDDEIPLSSKFQVKSNAGESINRSSNSGERKPLLSKYDQNGSASTE-- 1231
              ++  I   EDS+DE PLS +F  KS+ GES ++S +S E+KPL +K  QNGSAS +  
Sbjct: 181  SIRRPVIEESEDSEDEKPLSRRFPSKSSLGESTSKSYDSDEKKPLATKVQQNGSASRDGP 240

Query: 1232 -RKPSTNLKKRPGDGVKTTDESYLKKPKLSEAATPHKNKEASIKAEMREEDDE------- 1387
              K ++ L KR    VK+ ++S LKK KLS   T   NK+A++K E + EDD+       
Sbjct: 241  MNKSASLLNKRAPGEVKSLNQSSLKKAKLSSPITSISNKQAAVKPEPKAEDDDDNIPLSQ 300

Query: 1388 -----------------DHVPISHRMXXXXXXXXXXXXXXN-ITKPIXXXXXXXXXXXXX 1513
                             D+ PIS R+                 +  +             
Sbjct: 301  RGKKSQTAASKPKDEDDDNAPISQRIKKSPASVSKSSAPVKKASTVVSPSLKKVNKKSKK 360

Query: 1514 XXXXXXXXXXXXXXXXXGEGQKWTTLVHNGVIFPPPYKPHGVKMLYKGKPVDLTPEQEEV 1693
                             GEGQKWTTLVHNGV+F PPYKPHGVKMLYK +P+ LTPEQEEV
Sbjct: 361  VIKKTAYTKSSKVPPGSGEGQKWTTLVHNGVMFLPPYKPHGVKMLYKXQPLTLTPEQEEV 420

Query: 1694 ATMYAVMLETDYMNKPKFKENFMADWRKILGKNHTIQSLEHCDFTPIYEWHXXXXXXXXX 1873
            ATM+AVML+TDYM KP+FKENF +DW+K+LGKNHT+Q+LE CDF PIYEWH         
Sbjct: 421  ATMFAVMLDTDYMTKPRFKENFFSDWKKMLGKNHTVQNLEDCDFGPIYEWHQQEKEKRKQ 480

Query: 1874 XXXXXXXXXXXXXXXXXXXYMWAIVNGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIR 2053
                               YMWAIV+GVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIR
Sbjct: 481  MTTEEKKALKEERLQQEEKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIR 540

Query: 2054 PSDITINIGKDAPIPECPIPGESWKEIRHDNTVTWLAYWNDPINPKEFKYVFLAASSTLK 2233
            P DITINIGKDAPIPECPIPGE WKE+R+DNTVTWLA+WNDPIN KE KYVFLAASSTLK
Sbjct: 541  PRDITINIGKDAPIPECPIPGERWKEVRNDNTVTWLAFWNDPINQKECKYVFLAASSTLK 600

Query: 2234 GQSDKEKYEKARLLKDYILGIRAAYTKDFTS-KDPAKRQIAVATYLIDKLALRAGNEKDD 2410
            GQSDKEKYEKARLLKDYI GIRAAYTKDFT+ KDP K+QIAVATYLIDKLALRAGNEKDD
Sbjct: 601  GQSDKEKYEKARLLKDYIHGIRAAYTKDFTNNKDPMKKQIAVATYLIDKLALRAGNEKDD 660

Query: 2411 DEADTVGCCTLKVENVEPVPPNTLKFDFLGKDSIRYQNEVEVETAVFKAIQQFRSGKKGG 2590
            DEADTVGCCTLKVENVEPVPPN LK DF+GKDSIRYQNEV+VE AVFKAIQQFRSGK+G 
Sbjct: 661  DEADTVGCCTLKVENVEPVPPNILKIDFIGKDSIRYQNEVQVEPAVFKAIQQFRSGKEGC 720

Query: 2591 DDLFDRLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSRETRGGDVAEKVVVYQHA 2770
             DLFDRLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLS+ET+GG VAEKV VYQHA
Sbjct: 721  ADLFDRLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSKETKGGKVAEKVGVYQHA 780

Query: 2771 NKEVAIICNHQRTVSKSHSAQMLRLNEKIEELKGVVEELQTDLARAKKGKPPLKSADGKP 2950
            NKEVAIICNHQRTVSKSHSAQM RLNEKI+ELK  +EEL+TDL+RAKKGKPP K ADG+P
Sbjct: 781  NKEVAIICNHQRTVSKSHSAQMSRLNEKIDELKTALEELKTDLSRAKKGKPPAKGADGEP 840

Query: 2951 KRNLNPDALERKIAQTTAKIEKMERDKETKEDLKTVALGTSKINYLDPRITVAWCKRHEV 3130
            KRNLNP++LERKIAQT AKIEKMERDK+TKEDLK VAL TSKI+YLDPRITVAWCKRHEV
Sbjct: 841  KRNLNPESLERKIAQTNAKIEKMERDKKTKEDLKAVALSTSKISYLDPRITVAWCKRHEV 900

Query: 3131 PIEKIFNKSLLAKFAWAMDVDPGFRF 3208
            PIEKIFNKSLLAKFAW+MDVDP FRF
Sbjct: 901  PIEKIFNKSLLAKFAWSMDVDPSFRF 926


>ref|XP_009619726.1| PREDICTED: LOW QUALITY PROTEIN: DNA topoisomerase 1-like [Nicotiana
            tomentosiformis]
          Length = 877

 Score = 1095 bits (2832), Expect = 0.0
 Identities = 585/899 (65%), Positives = 650/899 (72%), Gaps = 6/899 (0%)
 Frame = +2

Query: 530  MAVEACDKQKLXXXXXXXXX--PLVFKRXXXXXXXXXXXXEAKKSLSQKHDRQLGRPAPD 703
            MAVEA  K KL           PLVFKR                S SQK D + GR A D
Sbjct: 1    MAVEAFSKTKLMAEVDDDDDDMPLVFKRSSTTSKQ-----NQSNSSSQKQDGRSGRQASD 55

Query: 704  VRSQNGQSTIVKKSKTVPLSKTPPVKYPLTSPKSSNTSGKALALKSPEVDSKPSTSVTDK 883
            VRS NGQS+  +K K    SK      P TSPK+S +SG+     SP  +S+PS S  ++
Sbjct: 56   VRSPNGQSSSAQKVKAGTSSKASRAVSPFTSPKASPSSGRT----SPAPNSRPSASAGNQ 111

Query: 884  SNSVKHQIK----DEKLSTEATGEPNEDSQDSEDDKPLSARLPAGLSKVNSNHAKKSPNT 1051
            +  V  Q K    + K + E   EPN++++DSEDDKPLSARL +GLSK NS+HA K   T
Sbjct: 112  AKDVNQQSKIVPNEPKQAVEPKSEPNDEAEDSEDDKPLSARLSSGLSKSNSSHANKVLGT 171

Query: 1052 STLSQKRRIPIPEDSDDEIPLSSKFQVKSNAGESINRSSNSGERKPLLSKYDQNGSASTE 1231
            S   QK R P  EDSDDEIPL+S+FQ+KSNAG S ++SSNS E KP   K  QNG  ST 
Sbjct: 172  SASVQKSRPPKKEDSDDEIPLASRFQLKSNAGASTSKSSNSEEVKP---KIRQNGLPST- 227

Query: 1232 RKPSTNLKKRPGDGVKTTDESYLKKPKLSEAATPHKNKEASIKAEMREEDDEDHVPISHR 1411
                T L KRP   V       LK           +   AS+K E + EDD+D VPIS R
Sbjct: 228  ----TVLSKRPPGDVSLLLRLQLKSLGFLMHLHLFRVSXASVKPEKKTEDDDDDVPISQR 283

Query: 1412 MXXXXXXXXXXXXXXNITKPIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXGEGQKWTTL 1591
            +                TK +                              GEGQKWTTL
Sbjct: 284  IKKSVASASKLSSAKKATKVVSSSMKTKKKLKKSKYSKSSKLQPSS-----GEGQKWTTL 338

Query: 1592 VHNGVIFPPPYKPHGVKMLYKGKPVDLTPEQEEVATMYAVMLETDYMNKPKFKENFMADW 1771
            VHNGVIFPPPYKPHGVKMLYKGKPVDLTPEQEEVATMYAVML+TDYM+K +FKENFM DW
Sbjct: 339  VHNGVIFPPPYKPHGVKMLYKGKPVDLTPEQEEVATMYAVMLDTDYMSKLQFKENFMNDW 398

Query: 1772 RKILGKNHTIQSLEHCDFTPIYEWHXXXXXXXXXXXXXXXXXXXXXXXXXXXXYMWAIVN 1951
            RKILGKNH IQ+L+ CDFTPIYEWH                            YMWAIV+
Sbjct: 399  RKILGKNHVIQNLDDCDFTPIYEWHQSEKEKKKQMSTEEKKALREEKLKQEEKYMWAIVD 458

Query: 1952 GVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIRPSDITINIGKDAPIPECPIPGESWKE 2131
            GVKEKVGNFRVEPPGLFRGRGEHPKMGKLK+RIRP+DITINIGK APIPECPIPGE WKE
Sbjct: 459  GVKEKVGNFRVEPPGLFRGRGEHPKMGKLKRRIRPNDITINIGKGAPIPECPIPGERWKE 518

Query: 2132 IRHDNTVTWLAYWNDPINPKEFKYVFLAASSTLKGQSDKEKYEKARLLKDYILGIRAAYT 2311
            +RHDNTVTWLA+WNDPINP+EFKYVFLAASS+LKGQSDKEKYEKAR LKDYI GIR+AYT
Sbjct: 519  VRHDNTVTWLAFWNDPINPREFKYVFLAASSSLKGQSDKEKYEKARRLKDYIEGIRSAYT 578

Query: 2312 KDFTSKDPAKRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVEPVPPNTLKFD 2491
            KDFTSKDP KRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVEPVPPN LKFD
Sbjct: 579  KDFTSKDPVKRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVEPVPPNILKFD 638

Query: 2492 FLGKDSIRYQNEVEVETAVFKAIQQFRSGKKGGDDLFDRLDTSKLNAHLKELMPGLTAKV 2671
            FLGKDSIRYQNEV V   VFKAIQ FRSGKKGGDDLFD+LDTSKLNAHLKELMPGLTAKV
Sbjct: 639  FLGKDSIRYQNEVAVYEPVFKAIQLFRSGKKGGDDLFDKLDTSKLNAHLKELMPGLTAKV 698

Query: 2672 FRTYNASITLDDMLSRETRGGDVAEKVVVYQHANKEVAIICNHQRTVSKSHSAQMLRLNE 2851
            FRTYNAS+TL+  L++ T+GG++AEKV VY  ANKEVAIICNHQR+VSKSHS Q+ +LNE
Sbjct: 699  FRTYNASVTLEQQLTKLTQGGELAEKVAVYNLANKEVAIICNHQRSVSKSHSVQISKLNE 758

Query: 2852 KIEELKGVVEELQTDLARAKKGKPPLKSADGKPKRNLNPDALERKIAQTTAKIEKMERDK 3031
            KI+ELK ++EE + DLARAKKGKPPLK ADGK KRNL P+AL++KI QT  KIE +ER  
Sbjct: 759  KIDELKALLEEFKVDLARAKKGKPPLKGADGKAKRNLAPEALQKKIDQTNVKIENIERQI 818

Query: 3032 ETKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFAWAMDVDPGFRF 3208
            ETKE+LKTVALGTSKINYLDPRITVAWCKRHEVPIEK+FNKSLLAKFAWAMDV+P F F
Sbjct: 819  ETKEELKTVALGTSKINYLDPRITVAWCKRHEVPIEKMFNKSLLAKFAWAMDVEPSFTF 877


>ref|XP_009790344.1| PREDICTED: LOW QUALITY PROTEIN: DNA topoisomerase 1-like [Nicotiana
            sylvestris]
          Length = 876

 Score = 1082 bits (2799), Expect = 0.0
 Identities = 576/899 (64%), Positives = 649/899 (72%), Gaps = 6/899 (0%)
 Frame = +2

Query: 530  MAVEACDKQKLXXXXXXXXX--PLVFKRXXXXXXXXXXXXEAKKSLSQKHDRQLGRPAPD 703
            MAVEA  K KL           PLVFKR                S SQK D + GR   D
Sbjct: 1    MAVEAFSKTKLMAEVDDDDDDMPLVFKRSTTSKQ------NQSNSSSQKQDGRSGRQVSD 54

Query: 704  VRSQNGQSTIVKKSKTVPLSKTPPVKYPLTSPKSSNTSGKALALKSPEVDSKPSTSVTDK 883
            VRS NGQ++  +K K    SK  P   P TSPK+S +S +     SP  +S+PS S  ++
Sbjct: 55   VRSPNGQNSSAQKVKAGTSSKASPAVSPFTSPKASPSSSRI----SPAPNSRPSASAGNQ 110

Query: 884  SNSVKHQIK----DEKLSTEATGEPNEDSQDSEDDKPLSARLPAGLSKVNSNHAKKSPNT 1051
            + +V  Q K    + K + E    PN++++DSEDDKPLSARL +GLSK  S+HA K   T
Sbjct: 111  AKNVNQQSKIVPNEPKQAVEPKSGPNDEAEDSEDDKPLSARLSSGLSKSISSHANKVLGT 170

Query: 1052 STLSQKRRIPIPEDSDDEIPLSSKFQVKSNAGESINRSSNSGERKPLLSKYDQNGSASTE 1231
            S   QK + P  EDSDDEIPL+S+FQ+KSNAG S ++SSNS E KP   K  QNG  ST 
Sbjct: 171  SASVQKSKPPKKEDSDDEIPLASRFQLKSNAGASTSKSSNSEEVKP---KIRQNGLPST- 226

Query: 1232 RKPSTNLKKRPGDGVKTTDESYLKKPKLSEAATPHKNKEASIKAEMREEDDEDHVPISHR 1411
                T L KRP   V       LK           +   AS+K E + EDD+D VPIS R
Sbjct: 227  ----TVLSKRPPGDVSLLLRLQLKSLGFLMHLHLFRLSXASVKPEKKTEDDDDDVPISQR 282

Query: 1412 MXXXXXXXXXXXXXXNITKPIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXGEGQKWTTL 1591
            +                TK +                              GEGQKWTTL
Sbjct: 283  IKKSVASASKVSSTKKATKVVSSSMKTKKKLKKSKYSKSSKLQPSS-----GEGQKWTTL 337

Query: 1592 VHNGVIFPPPYKPHGVKMLYKGKPVDLTPEQEEVATMYAVMLETDYMNKPKFKENFMADW 1771
            VHNGVIFPP YKPHGVKMLYKGKP++LTPEQEEVATMYAVML+T+YM+KP+FKENFM DW
Sbjct: 338  VHNGVIFPPSYKPHGVKMLYKGKPINLTPEQEEVATMYAVMLDTEYMSKPQFKENFMNDW 397

Query: 1772 RKILGKNHTIQSLEHCDFTPIYEWHXXXXXXXXXXXXXXXXXXXXXXXXXXXXYMWAIVN 1951
            RKILGKNH IQ+L+ CDFTPIYEWH                            YMWAIV+
Sbjct: 398  RKILGKNHVIQNLDDCDFTPIYEWHQSEKEKKKQMSTEEKKALREEKLKQEEKYMWAIVD 457

Query: 1952 GVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIRPSDITINIGKDAPIPECPIPGESWKE 2131
            GVKEKVGNFRVEPPGLFRGRGEHPKMGKLK+RIRP+DITINIGK APIPECPIPGE WKE
Sbjct: 458  GVKEKVGNFRVEPPGLFRGRGEHPKMGKLKRRIRPNDITINIGKGAPIPECPIPGERWKE 517

Query: 2132 IRHDNTVTWLAYWNDPINPKEFKYVFLAASSTLKGQSDKEKYEKARLLKDYILGIRAAYT 2311
            +RHDNTVTWLA+WNDPINP+EFKYVFLAASS+LKGQSDKEKYEKAR LKDYI GIR+AYT
Sbjct: 518  VRHDNTVTWLAFWNDPINPREFKYVFLAASSSLKGQSDKEKYEKARRLKDYIEGIRSAYT 577

Query: 2312 KDFTSKDPAKRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVEPVPPNTLKFD 2491
            KDFTSKDP KRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVEPVPPN LKFD
Sbjct: 578  KDFTSKDPVKRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVEPVPPNILKFD 637

Query: 2492 FLGKDSIRYQNEVEVETAVFKAIQQFRSGKKGGDDLFDRLDTSKLNAHLKELMPGLTAKV 2671
            FLGKDSIRYQNEV V   VFKAIQ FRSGKKGGDDLFD+LDTSKLNAHLKELMPGLTAKV
Sbjct: 638  FLGKDSIRYQNEVAVYEPVFKAIQLFRSGKKGGDDLFDKLDTSKLNAHLKELMPGLTAKV 697

Query: 2672 FRTYNASITLDDMLSRETRGGDVAEKVVVYQHANKEVAIICNHQRTVSKSHSAQMLRLNE 2851
            FRTYNAS+TL+  L++ T+GG++AEKV VY  ANKEVAIICNHQR+VSKSHS Q+ +LNE
Sbjct: 698  FRTYNASVTLEQQLTKLTQGGELAEKVAVYNLANKEVAIICNHQRSVSKSHSVQISKLNE 757

Query: 2852 KIEELKGVVEELQTDLARAKKGKPPLKSADGKPKRNLNPDALERKIAQTTAKIEKMERDK 3031
            KI+ELK ++EE + DLARAKKGKPPLK ADGK KRNL P+AL++K+ QT AKIE +E+  
Sbjct: 758  KIDELKALLEEFKVDLARAKKGKPPLKGADGKAKRNLAPEALQKKMDQTNAKIENIEKQI 817

Query: 3032 ETKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFAWAMDVDPGFRF 3208
            ETKE+LKTVALGTSKINYLDPRITVAWCKRHEVPIEK+FNKSLLAKFAWAMDV+P F F
Sbjct: 818  ETKEELKTVALGTSKINYLDPRITVAWCKRHEVPIEKMFNKSLLAKFAWAMDVEPSFTF 876


>dbj|BAK32959.1| topoisomerase I [Ophiorrhiza plumbea]
          Length = 920

 Score = 1082 bits (2799), Expect = 0.0
 Identities = 575/920 (62%), Positives = 652/920 (70%), Gaps = 34/920 (3%)
 Frame = +2

Query: 530  MAVEACDKQKLXXXXXXXXXPLVFKRXXXXXXXXXXXXEAKKSLSQKHDRQLGRPAPDVR 709
            MAVEAC    L         P++FKR            E KK   QKH  Q      DVR
Sbjct: 1    MAVEACTTPNLMEDMEDDEGPVIFKRSNPASKQNQANSEKKKLSLQKHVGQSAVHTSDVR 60

Query: 710  SQNGQSTIVKKSKTVPLSKTPPVKYPLTSPKSSNTSGKALALKSPEVDSKPSTSVTDKSN 889
              NG+S+  +K +  P ++TPPVK PL+SPK+SN+S KA  + SP  +SK S S T  + 
Sbjct: 61   PANGESSSAQKGRIQPSAETPPVKSPLSSPKASNSSAKASPITSPGANSKLSASATSTAK 120

Query: 890  SVKHQIKD----EKLSTEATGEPNEDSQDSEDDKPLSARLPAGLSKVNSNHAKKSPNTST 1057
               H        E   +    + N +S+ S+D+KPL AR     SK  SNHA K    S 
Sbjct: 121  QQNHHKSSAAFIEPKPSVPAAKANSNSESSDDEKPLIARTSGCSSKGKSNHANKEGGDSC 180

Query: 1058 LSQKRRIPIPEDSDDEIPLSSKFQVKSNAGESINRSSNSGERKPLLSKYDQNGSASTE-- 1231
              ++  I   EDS+DE PLS +F  KS+ GES ++S +S E+KPL +K   NGSAS +  
Sbjct: 181  SIRRPVIEESEDSEDEKPLSRRFPSKSSLGESTSKSYDSDEKKPLAAKVQPNGSASRDGP 240

Query: 1232 --RKPSTNLKKRPGDGVKTTDESYLKKPKLSEAATPHKNKEASIKAEMREEDDE------ 1387
              +  S + K+ PG+ VK+ ++S LKKPKLS   T   NK+A++K E + EDD+      
Sbjct: 241  MNKSASLSNKRAPGE-VKSLNQSSLKKPKLSSPITSISNKQAAVKPEPKAEDDDDNIPLS 299

Query: 1388 ------------------DHVPISHRMXXXXXXXXXXXXXXN-ITKPIXXXXXXXXXXXX 1510
                              D+ PIS R+                 +  +            
Sbjct: 300  QRGKKSQTAASKPKDEDDDNAPISQRIKKSPASVSKSSAPVKKASTVVSPSLKKVNKKSK 359

Query: 1511 XXXXXXXXXXXXXXXXXXGEGQKWTTLVHNGVIFPPPYKPHGVKMLYKGKPVDLTPEQEE 1690
                              GEGQKWTTLVHNGVIFPPPYKPHGVKMLYK +P+ LTPEQEE
Sbjct: 360  KVIKKTAYTKSSKVPPGSGEGQKWTTLVHNGVIFPPPYKPHGVKMLYKRQPITLTPEQEE 419

Query: 1691 VATMYAVMLETDYMNKPKFKENFMADWRKILGKNHTIQSLEHCDFTPIYEWHXXXXXXXX 1870
            VATM+AVML+TDYMNKP+FKENF +DW+K+LGKNHTIQ+LE CDF PIYEWH        
Sbjct: 420  VATMFAVMLDTDYMNKPRFKENFFSDWKKMLGKNHTIQNLEDCDFGPIYEWHQQEKEKKK 479

Query: 1871 XXXXXXXXXXXXXXXXXXXXYMWAIVNGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRI 2050
                                YMW IV+GVKEKVGNFRVEPPGLFRGRGEHPK+GKLKKRI
Sbjct: 480  QMTTEEKKALKEERLQQEEKYMWVIVDGVKEKVGNFRVEPPGLFRGRGEHPKVGKLKKRI 539

Query: 2051 RPSDITINIGKDAPIPECPIPGESWKEIRHDNTVTWLAYWNDPINPKEFKYVFLAASSTL 2230
            RP DITINIGKDAPIPECPIPGE WKE+R+DNTVTWLAYWNDPIN KE KYVFL ASSTL
Sbjct: 540  RPRDITINIGKDAPIPECPIPGERWKEVRNDNTVTWLAYWNDPINQKERKYVFLGASSTL 599

Query: 2231 KGQSDKEKYEKARLLKDYILGIRAAYTKDFTS-KDPAKRQIAVATYLIDKLALRAGNEKD 2407
            KGQSDKEKYEKARLLKDYI GIRAAYTKDFT+ KDP K+QIAVATYLIDKLALRAGNEKD
Sbjct: 600  KGQSDKEKYEKARLLKDYIHGIRAAYTKDFTNNKDPMKKQIAVATYLIDKLALRAGNEKD 659

Query: 2408 DDEADTVGCCTLKVENVEPVPPNTLKFDFLGKDSIRYQNEVEVETAVFKAIQQFRSGKKG 2587
            DDEADTVGCCTLKVENVEPVPPN LK DF+GKDSIRYQNEV+VE AVFKAIQQFRSGK+G
Sbjct: 660  DDEADTVGCCTLKVENVEPVPPNILKIDFIGKDSIRYQNEVQVEPAVFKAIQQFRSGKEG 719

Query: 2588 GDDLFDRLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSRETRGGDVAEKVVVYQH 2767
              DLFDRLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLS+ET+GG VAEKV VYQH
Sbjct: 720  SADLFDRLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSKETKGGKVAEKVGVYQH 779

Query: 2768 ANKEVAIICNHQRTVSKSHSAQMLRLNEKIEELKGVVEELQTDLARAKKGKPPLKSADGK 2947
            ANKEVAIICNHQRTVSKSHSAQM RLNEKI+ELK  +EEL+TDL+RAKKGKPP K ADG+
Sbjct: 780  ANKEVAIICNHQRTVSKSHSAQMSRLNEKIDELKTALEELKTDLSRAKKGKPPSKGADGE 839

Query: 2948 PKRNLNPDALERKIAQTTAKIEKMERDKETKEDLKTVALGTSKINYLDPRITVAWCKRHE 3127
            PKRNLNP+ALERKIAQT AKIEKME DK+TKEDLK VAL TSKI+YL PRITVAWCKRHE
Sbjct: 840  PKRNLNPEALERKIAQTNAKIEKMEGDKKTKEDLKAVALSTSKISYLGPRITVAWCKRHE 899

Query: 3128 VPIEKIFNKSLLAKFAWAMD 3187
            VPIEK+FNKSLLAKFAWAM+
Sbjct: 900  VPIEKMFNKSLLAKFAWAMN 919


>dbj|BAK32963.1| topoisomerase I [Ophiorrhiza sp. 35]
          Length = 920

 Score = 1082 bits (2798), Expect = 0.0
 Identities = 573/920 (62%), Positives = 654/920 (71%), Gaps = 34/920 (3%)
 Frame = +2

Query: 530  MAVEACDKQKLXXXXXXXXXPLVFKRXXXXXXXXXXXXEAKKSLSQKHDRQLGRPAPDVR 709
            MAVEAC    L         P++FKR            E KK   QKH  Q      DVR
Sbjct: 1    MAVEACTTTNLMEDMEDDEGPVIFKRSNPASKQNQANSEKKKLSLQKHVGQSAVHTSDVR 60

Query: 710  SQNGQSTIVKKSKTVPLSKTPPVKYPLTSPKSSNTSGKALALKSPEVDSKPSTSVTDKSN 889
              NG+S+  +K +  P ++TPPVK PL+SPK+SN+S KA  + SP  +SK S S T  + 
Sbjct: 61   PANGESSSAQKGRIQPSAETPPVKSPLSSPKASNSSAKASPITSPGANSKLSASATSTAK 120

Query: 890  SVKHQIKD----EKLSTEATGEPNEDSQDSEDDKPLSARLPAGLSKVNSNHAKKSPNTST 1057
               H        E   +    + N +S+ S+D+KPL AR     SK  SNHA K    S 
Sbjct: 121  QQNHHKSSAAFIEPKPSVPPAKANSNSESSDDEKPLIARTSGCSSKGKSNHANKEGGDSC 180

Query: 1058 LSQKRRIPIPEDSDDEIPLSSKFQVKSNAGESINRSSNSGERKPLLSKYDQNGSASTE-- 1231
              ++  +   EDS+DE PLS +F  KS+ GES ++S +S E+KPL +K  QNGSAS +  
Sbjct: 181  SIRRPVVEESEDSEDEKPLSRRFPSKSSLGESTSKSYDSDEKKPLAAKVQQNGSASRDGP 240

Query: 1232 --RKPSTNLKKRPGDGVKTTDESYLKKPKLSEAATPHKNKEASIKAEMREEDDE------ 1387
              +  S + K+ PG+ VK+ ++S LKKPKLS   T   NK+A++K E + EDD+      
Sbjct: 241  MNKSASLSNKRAPGE-VKSLNQSSLKKPKLSSPITSISNKQAAVKPEPKAEDDDDNIPLS 299

Query: 1388 ------------------DHVPISHRMXXXXXXXXXXXXXXN-ITKPIXXXXXXXXXXXX 1510
                              D+ PIS R+                 +  +            
Sbjct: 300  QRGKKSQTAASKPKDEDDDNAPISQRIKKSPASVSKSSAPVKKASTVVSPSLKKVNKKSK 359

Query: 1511 XXXXXXXXXXXXXXXXXXGEGQKWTTLVHNGVIFPPPYKPHGVKMLYKGKPVDLTPEQEE 1690
                              GEGQKWTTLVHNGVIFPPPYKPHGVKMLYK +P+ LTPEQEE
Sbjct: 360  KVIKKTAYTKSSKVPPGSGEGQKWTTLVHNGVIFPPPYKPHGVKMLYKRQPLTLTPEQEE 419

Query: 1691 VATMYAVMLETDYMNKPKFKENFMADWRKILGKNHTIQSLEHCDFTPIYEWHXXXXXXXX 1870
            VATM+AVML+TDYMNKP+FKENF +DW+K+LGKNHTIQ+LE CDF PIYEWH        
Sbjct: 420  VATMFAVMLDTDYMNKPRFKENFFSDWKKMLGKNHTIQNLEDCDFGPIYEWHQQEREKKK 479

Query: 1871 XXXXXXXXXXXXXXXXXXXXYMWAIVNGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRI 2050
                                YMWAIV+GVKEKVGNFRVEPPGLFRGRGEHPK+GKLKKRI
Sbjct: 480  QMTTEEKKALKDERLQQEEKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKVGKLKKRI 539

Query: 2051 RPSDITINIGKDAPIPECPIPGESWKEIRHDNTVTWLAYWNDPINPKEFKYVFLAASSTL 2230
             P DITINIGKDAPIPECPIPGE WKE+R+DNTVTWLAYWNDP+N KE KYVFLA SSTL
Sbjct: 540  HPRDITINIGKDAPIPECPIPGERWKEVRNDNTVTWLAYWNDPVNLKECKYVFLAPSSTL 599

Query: 2231 KGQSDKEKYEKARLLKDYILGIRAAYTKDFTS-KDPAKRQIAVATYLIDKLALRAGNEKD 2407
            KGQSDKEKYEKARLLKDYI GIRAAYTKDFT+ KDP K+QIAVATYLIDKLALRAGNEKD
Sbjct: 600  KGQSDKEKYEKARLLKDYIHGIRAAYTKDFTNNKDPMKKQIAVATYLIDKLALRAGNEKD 659

Query: 2408 DDEADTVGCCTLKVENVEPVPPNTLKFDFLGKDSIRYQNEVEVETAVFKAIQQFRSGKKG 2587
            DDEADTVGCCTL+VENVEPVPPN LK DF+GKDSIRYQNEV+VE AVFKAIQQFRSGK+G
Sbjct: 660  DDEADTVGCCTLRVENVEPVPPNILKIDFIGKDSIRYQNEVQVEPAVFKAIQQFRSGKEG 719

Query: 2588 GDDLFDRLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSRETRGGDVAEKVVVYQH 2767
             +DLFDRLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLS+ET+GG VAEKV VYQH
Sbjct: 720  SEDLFDRLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSKETKGGKVAEKVGVYQH 779

Query: 2768 ANKEVAIICNHQRTVSKSHSAQMLRLNEKIEELKGVVEELQTDLARAKKGKPPLKSADGK 2947
            ANKEVAIICNHQRTVSKSHSAQM RLNEKI+ELK  +EEL+TDL+RAKKGKPP K  DG+
Sbjct: 780  ANKEVAIICNHQRTVSKSHSAQMSRLNEKIDELKTALEELKTDLSRAKKGKPPSKGDDGE 839

Query: 2948 PKRNLNPDALERKIAQTTAKIEKMERDKETKEDLKTVALGTSKINYLDPRITVAWCKRHE 3127
            PKRNLNP+ALERKIAQT AKIEKMERDK+TKEDLK VAL TSKI+YLDPRITVAWCKR E
Sbjct: 840  PKRNLNPEALERKIAQTNAKIEKMERDKKTKEDLKAVALSTSKISYLDPRITVAWCKRQE 899

Query: 3128 VPIEKIFNKSLLAKFAWAMD 3187
            VPIEK+FNKSLLAKFAWAM+
Sbjct: 900  VPIEKMFNKSLLAKFAWAMN 919


>ref|XP_010266803.1| PREDICTED: DNA topoisomerase 1-like [Nelumbo nucifera]
          Length = 890

 Score = 1064 bits (2751), Expect = 0.0
 Identities = 569/910 (62%), Positives = 646/910 (70%), Gaps = 16/910 (1%)
 Frame = +2

Query: 527  LMAVEACDKQKLXXXXXXXXXPLVFKRXXXXXXXXXXXXEAKKSLSQKHDRQLGRPAPDV 706
            +MAV+AC K K          P++FKR            E KK  S+K D   G+   D 
Sbjct: 1    MMAVDACIKPKFFDDGDDDEGPIIFKRNNASSKKNQLNKELKKVSSRKRDGSSGKCVSDS 60

Query: 707  RSQNGQSTIVKKSKTVPLSKTPPVKYPLTSPKSSNTSGKALALKSPEVDSKPSTSVTDK- 883
             S NGQ++ ++K K V                    S KA   KS E  SK STS+TDK 
Sbjct: 61   FSPNGQNSSLQKGKAVQ-------------------SSKASTGKSTETSSKASTSITDKL 101

Query: 884  -SNSVKHQIKD--EKLSTEATGEPNEDSQDSEDDKPLSARLP--AGLSKVNSNHAKKSPN 1048
              +  K+   D  EK   +   EP  DS DS+DDKPLS RLP  A L K  S+   K  +
Sbjct: 102  KCSPQKNSSIDNMEKQLKKPCNEPYTDSVDSDDDKPLSIRLPTSASLLKCKSSPVSKGLS 161

Query: 1049 T----STLSQKRRIP---IPEDSDDEIPLSSKFQVKSNAGESINRSSNSGERKPLLSKYD 1207
            +    S+ S+K  +      EDS+DE+PLS K ++K + G S  +  +SGE KPL+SK  
Sbjct: 162  SPVASSSQSEKTNVTNKKSSEDSEDELPLSLKLKLKPSVGLSGKKFYDSGEEKPLVSKLQ 221

Query: 1208 QNGSASTERKP---STNLKKRPGDGVKTTDESYLKKPKLSEAATPHKNKEASIKAEMREE 1378
            QNGS+  + +P     NL KRP  G  ++ +S +KK K+SE + P K K+ SIK+E +EE
Sbjct: 222  QNGSSKRDNEPLKSPKNLNKRPLSGANSSGQSLVKKLKVSEVSVPTKVKQTSIKSEPKEE 281

Query: 1379 DDEDHVPISHRMXXXXXXXXXXXXXXNITKPIXXXXXXXXXXXXXXXXXXXXXXXXXXXX 1558
            D++D +PIS R+                TK +                            
Sbjct: 282  DEDD-IPISQRLKKSASSDDKSLSLKKTTKVVSSSFKKTTNKLKKAAKNSKYSKSTKMPP 340

Query: 1559 XXGEGQKWTTLVHNGVIFPPPYKPHGVKMLYKGKPVDLTPEQEEVATMYAVMLETDYMNK 1738
              GEGQKWTTL HNGVIFPP YKPHGVKMLY GKPVDLTPEQEEVATM+AVM +TDY  K
Sbjct: 341  SSGEGQKWTTLEHNGVIFPPLYKPHGVKMLYNGKPVDLTPEQEEVATMFAVMKDTDYATK 400

Query: 1739 PKFKENFMADWRKILGKNHTIQSLEHCDFTPIYEWHXXXXXXXXXXXXXXXXXXXXXXXX 1918
             +F ENFM DWR ILGKNH I+  E CDFTPIYEWH                        
Sbjct: 401  SRFIENFMNDWRTILGKNHVIKKFELCDFTPIYEWHQREKEKKKQMSAEEKKALKEEKLK 460

Query: 1919 XXXXYMWAIVNGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIRPSDITINIGKDAPIP 2098
                YMWAIV+GVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRI PSDITINIGK APIP
Sbjct: 461  QEEKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIHPSDITINIGKGAPIP 520

Query: 2099 ECPIPGESWKEIRHDNTVTWLAYWNDPINPKEFKYVFLAASSTLKGQSDKEKYEKARLLK 2278
            ECPIPGE WKE+RHDNTVTWLA+WNDPINPKEFKYVFLAASS+LKGQSDKEKYEKARLLK
Sbjct: 521  ECPIPGERWKEVRHDNTVTWLAFWNDPINPKEFKYVFLAASSSLKGQSDKEKYEKARLLK 580

Query: 2279 DYILGIRAAYTKDFTSKDPAKRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENV 2458
            DYI  IRA YT+DF SKD  KRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENV
Sbjct: 581  DYIKDIRANYTRDFVSKDITKRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENV 640

Query: 2459 EPVPPNTLKFDFLGKDSIRYQNEVEVETAVFKAIQQFRSGKKGGDDLFDRLDTSKLNAHL 2638
            E VPPN L+FDFLGKDSIRY N VEVE AV+KAI QF++GK+ G+DLFD LDTSKLNAHL
Sbjct: 641  ELVPPNKLQFDFLGKDSIRYFNTVEVELAVYKAIGQFKNGKEDGEDLFDSLDTSKLNAHL 700

Query: 2639 KELMPGLTAKVFRTYNASITLDDMLSRETRGGDVAEKVVVYQHANKEVAIICNHQRTVSK 2818
            KELMPGLTAKVFRTYNASITLD+ML+RE++GGDVAEK+ VYQHANKEVAIICNHQR+VSK
Sbjct: 701  KELMPGLTAKVFRTYNASITLDEMLNRESKGGDVAEKIAVYQHANKEVAIICNHQRSVSK 760

Query: 2819 SHSAQMLRLNEKIEELKGVVEELQTDLARAKKGKPPLKSADGKPKRNLNPDALERKIAQT 2998
            SHSAQM RL++KI+ELK  ++EL+TDLARAKKGKPPLK ADGKPKRNL P+ALE+KIAQ 
Sbjct: 761  SHSAQMHRLDDKIKELKDALDELKTDLARAKKGKPPLKGADGKPKRNLTPEALEKKIAQA 820

Query: 2999 TAKIEKMERDKETKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFAW 3178
             AKIEKMERDK+ KEDLKTVALGTSKINYLDPRI+VAWCKRHEVPIEKIFNKSLLAKFAW
Sbjct: 821  NAKIEKMERDKQIKEDLKTVALGTSKINYLDPRISVAWCKRHEVPIEKIFNKSLLAKFAW 880

Query: 3179 AMDVDPGFRF 3208
            AMDVDP FRF
Sbjct: 881  AMDVDPDFRF 890