BLASTX 2.2.26 [Sep-21-2011]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= Rehmannia27_contig00017470
         (2463 letters)

Database: ./nr 
           84,704,028 sequences; 31,038,470,784 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

ref|XP_012857604.1| PREDICTED: DNA topoisomerase 3-alpha [Erythr...  1437   0.0  
ref|XP_011100133.1| PREDICTED: DNA topoisomerase 3-alpha [Sesamu...  1430   0.0  
ref|XP_006341743.1| PREDICTED: DNA topoisomerase 3-alpha [Solanu...  1349   0.0  
ref|XP_015074855.1| PREDICTED: DNA topoisomerase 3-alpha isoform...  1342   0.0  
ref|XP_009622049.1| PREDICTED: DNA topoisomerase 3-alpha isoform...  1338   0.0  
ref|XP_010320982.1| PREDICTED: DNA topoisomerase 3-alpha isoform...  1336   0.0  
ref|XP_010649354.1| PREDICTED: DNA topoisomerase 3-alpha isoform...  1301   0.0  
ref|XP_010649353.1| PREDICTED: DNA topoisomerase 3-alpha isoform...  1301   0.0  
ref|XP_009622050.1| PREDICTED: DNA topoisomerase 3-alpha isoform...  1300   0.0  
ref|XP_010270299.1| PREDICTED: DNA topoisomerase 3-alpha [Nelumb...  1298   0.0  
ref|XP_015074856.1| PREDICTED: DNA topoisomerase 3-alpha isoform...  1291   0.0  
ref|XP_010649355.1| PREDICTED: DNA topoisomerase 3-alpha isoform...  1290   0.0  
ref|XP_010674423.1| PREDICTED: DNA topoisomerase 3-alpha isoform...  1289   0.0  
ref|XP_010674422.1| PREDICTED: DNA topoisomerase 3-alpha isoform...  1289   0.0  
emb|CDP04613.1| unnamed protein product [Coffea canephora]           1289   0.0  
gb|KNA10476.1| hypothetical protein SOVF_143990 [Spinacia oleracea]  1286   0.0  
ref|XP_004502963.1| PREDICTED: DNA topoisomerase 3-alpha [Cicer ...  1278   0.0  
ref|XP_007048481.1| Topoisomerase 3alpha isoform 2, partial [The...  1276   0.0  
ref|XP_007048480.1| Topoisomerase 3alpha isoform 1 [Theobroma ca...  1276   0.0  
ref|XP_012489371.1| PREDICTED: DNA topoisomerase 3-alpha isoform...  1266   0.0  

>ref|XP_012857604.1| PREDICTED: DNA topoisomerase 3-alpha [Erythranthe guttata]
            gi|604300824|gb|EYU20574.1| hypothetical protein
            MIMGU_mgv1a000984mg [Erythranthe guttata]
          Length = 923

 Score = 1437 bits (3720), Expect = 0.0
 Identities = 688/757 (90%), Positives = 717/757 (94%)
 Frame = -1

Query: 2367 MAGGGGRPLRALNVAEKPSVAKAVSGILSKTPSSGGLRVRDGRSRYNRIFEFNYTIQNQQ 2188
            MAGGGGRPLRALNVAEKPSVAKAVSGILSK PSSGGLRVR+GRSRYN+IFEFNY IQNQQ
Sbjct: 1    MAGGGGRPLRALNVAEKPSVAKAVSGILSKNPSSGGLRVREGRSRYNKIFEFNYAIQNQQ 60

Query: 2187 VHMSFTSVTGHLMELDFEDRYRKWHSCDPVDLYHAPVKKYVPEDKSEIEKTLEEEARKCQ 2008
              MSFTSVTGHLMEL+FEDRYRKWHSCDPVDLYHAPV+K+VP+DKS+IEKTLEEEARKCQ
Sbjct: 61   FQMSFTSVTGHLMELEFEDRYRKWHSCDPVDLYHAPVRKHVPQDKSDIEKTLEEEARKCQ 120

Query: 2007 WLILWLDCDREGENIAFEVVEVCTRANRNLNIWRARFSALIDREIHYSVQHLVRPNQLFS 1828
            WLILWLDCDREGENIAFEVVE C R NRNLNIWRARFSALIDREIH +VQHLVRPNQLF+
Sbjct: 121  WLILWLDCDREGENIAFEVVEACLRTNRNLNIWRARFSALIDREIHDAVQHLVRPNQLFA 180

Query: 1827 DAVDARQEIDLRIGASFTRFQTMLLRDAFVLDFATDNTNVILSYGPCQFPTLGFIVERFW 1648
            DAVD RQEIDLRIGASFTRFQTMLL+DAFVLDFAT+  NVILSYGPCQFPTLGF+VERFW
Sbjct: 181  DAVDVRQEIDLRIGASFTRFQTMLLKDAFVLDFATEERNVILSYGPCQFPTLGFVVERFW 240

Query: 1647 EVQSHEPEEFWTINCTHNSEEGTATFNWMRGHLFDYTCAMIIYEMCVQEPTATVTNVRQQ 1468
            E+QSHEPEEFWTINCTHNSEEGTATF+WMRGHLFDYTCA IIYEMCV EP ATVTNVR Q
Sbjct: 241  EIQSHEPEEFWTINCTHNSEEGTATFSWMRGHLFDYTCATIIYEMCVLEPNATVTNVRNQ 300

Query: 1467 EKLKYPPHPLSTIELEKRASRYFRMSSEHTMKVAEDLYQAGFISYPRTETDCFSVRTDLH 1288
            EK +YPPHPLSTIELEKRASRYFRMSSE TMKVAEDLYQAGFISYPRTETD FSVRTDLH
Sbjct: 301  EKPRYPPHPLSTIELEKRASRYFRMSSEQTMKVAEDLYQAGFISYPRTETDSFSVRTDLH 360

Query: 1287 TIVQEQQGHPVWGSYAQRLLDPEASLWRNPSGGGHDDKAHPPIHPTKFSAGESGWSPDHH 1108
            TIVQEQQGHP WGSYAQRLLDPEA LWRNPS GGHDDKAHPPIHPTKFSAGESGWS DHH
Sbjct: 361  TIVQEQQGHPTWGSYAQRLLDPEAGLWRNPSSGGHDDKAHPPIHPTKFSAGESGWSQDHH 420

Query: 1107 KVYELVVRHFLACVSQPAIGAETTVEIDIACEQFSASGRVIIAKNYLDVYRFETWGGSMI 928
            KVYELVVRHFLACVSQPAIGA TTV+IDIA EQFSASG VI+AKNYLDVYRFETWGGSMI
Sbjct: 421  KVYELVVRHFLACVSQPAIGAVTTVDIDIAGEQFSASGTVILAKNYLDVYRFETWGGSMI 480

Query: 927  PTYNYGQQFTPTTLTLDAGVTRPPPLLSEADLLSCMDKAGIGTDATMHDHIKKLLDRFYA 748
            PTYNYGQQFTPTTLTLD+GVTRPPPLLSEADLLSCMD AGIGTDATMHDHIKKLLDRFYA
Sbjct: 481  PTYNYGQQFTPTTLTLDSGVTRPPPLLSEADLLSCMDNAGIGTDATMHDHIKKLLDRFYA 540

Query: 747  TKDSSMRFSPTKLGEALVMGYDDMGYELWKPYLRAMMESDMKAVSMGTKRKAEVLEACLQ 568
            TKDS+MRFSPTKLGEALV GYDDMGYELWKP LRAMMESDMKAVSMGTKRK+EVL++CLQ
Sbjct: 541  TKDSNMRFSPTKLGEALVKGYDDMGYELWKPNLRAMMESDMKAVSMGTKRKSEVLDSCLQ 600

Query: 567  QMKACFVDARLNKGKLFEAMAVFFERSNRSNSNEQHAIGEVVRKCGLCQESDMVLRKKPD 388
            QMKACFVDARLNK KLFEAM VFFERSNR+N NEQ AIGEVVRKCGLCQESDMVLRKKPD
Sbjct: 601  QMKACFVDARLNKEKLFEAMDVFFERSNRANGNEQQAIGEVVRKCGLCQESDMVLRKKPD 660

Query: 387  GNFMVGCLGFPQCRNVVWLPGSVSEAIVTTNICSTCSPGPVYLIQFKFRRLEIPPNYNVN 208
            GNFMVGCLG+PQCRNVVWLPGSVSEA VTT ICSTCSPGPVY+IQFKFRRLEIPPNYNV+
Sbjct: 661  GNFMVGCLGYPQCRNVVWLPGSVSEATVTTTICSTCSPGPVYMIQFKFRRLEIPPNYNVD 720

Query: 207  HLGCIGGCDDILRQLVEVCGTGSRNNSSVPGMYEMHS 97
            HLGCIGGCDD LRQLVE+CGTGSR  SSVPG  + H+
Sbjct: 721  HLGCIGGCDDTLRQLVEICGTGSRTTSSVPGRGQGHT 757


>ref|XP_011100133.1| PREDICTED: DNA topoisomerase 3-alpha [Sesamum indicum]
          Length = 906

 Score = 1430 bits (3702), Expect = 0.0
 Identities = 682/757 (90%), Positives = 719/757 (94%)
 Frame = -1

Query: 2367 MAGGGGRPLRALNVAEKPSVAKAVSGILSKTPSSGGLRVRDGRSRYNRIFEFNYTIQNQQ 2188
            MAGGGGRPLRALNVAEKPSVAKAVSGIL++ PSSGGLRVR+GRSRYN+IFEFNY IQNQQ
Sbjct: 1    MAGGGGRPLRALNVAEKPSVAKAVSGILARNPSSGGLRVREGRSRYNKIFEFNYAIQNQQ 60

Query: 2187 VHMSFTSVTGHLMELDFEDRYRKWHSCDPVDLYHAPVKKYVPEDKSEIEKTLEEEARKCQ 2008
             HM+FTSVTGHLME++FEDRYRKWHSCDPVDLYHAPVKK+VP DKS+IEKTLEEEARK Q
Sbjct: 61   FHMAFTSVTGHLMEVEFEDRYRKWHSCDPVDLYHAPVKKHVPHDKSDIEKTLEEEARKSQ 120

Query: 2007 WLILWLDCDREGENIAFEVVEVCTRANRNLNIWRARFSALIDREIHYSVQHLVRPNQLFS 1828
            WLILWLDCDREGENIAFEVVEVCTRANRNLNIWRARFSALIDREIHY+ QHL+RPNQLF+
Sbjct: 121  WLILWLDCDREGENIAFEVVEVCTRANRNLNIWRARFSALIDREIHYAAQHLIRPNQLFA 180

Query: 1827 DAVDARQEIDLRIGASFTRFQTMLLRDAFVLDFATDNTNVILSYGPCQFPTLGFIVERFW 1648
            DAVD RQEIDLRIGASFTRFQTMLLRDAFVLDF TD+ NVILSYGPCQF          W
Sbjct: 181  DAVDVRQEIDLRIGASFTRFQTMLLRDAFVLDFTTDDKNVILSYGPCQF----------W 230

Query: 1647 EVQSHEPEEFWTINCTHNSEEGTATFNWMRGHLFDYTCAMIIYEMCVQEPTATVTNVRQQ 1468
            E+QSHEPEEFWTINCTHNSEEGTATFNWMRGHLFDYTCA I+YEMCVQEPTATVTNVRQQ
Sbjct: 231  EIQSHEPEEFWTINCTHNSEEGTATFNWMRGHLFDYTCATILYEMCVQEPTATVTNVRQQ 290

Query: 1467 EKLKYPPHPLSTIELEKRASRYFRMSSEHTMKVAEDLYQAGFISYPRTETDCFSVRTDLH 1288
            EK KYPPHPLSTIELEKRASRYFRMSSE TMKVAEDLYQAGFISYPRTETDCFS RTDLH
Sbjct: 291  EKPKYPPHPLSTIELEKRASRYFRMSSEQTMKVAEDLYQAGFISYPRTETDCFSERTDLH 350

Query: 1287 TIVQEQQGHPVWGSYAQRLLDPEASLWRNPSGGGHDDKAHPPIHPTKFSAGESGWSPDHH 1108
             IVQ+QQ HP+WGSYAQRLLDPE+ LWRNPSGGGHDDKAHPPIHPTKFS+GESGWS DHH
Sbjct: 351  RIVQDQQAHPIWGSYAQRLLDPESGLWRNPSGGGHDDKAHPPIHPTKFSSGESGWSQDHH 410

Query: 1107 KVYELVVRHFLACVSQPAIGAETTVEIDIACEQFSASGRVIIAKNYLDVYRFETWGGSMI 928
            KVYELVVRHFLACVSQPAIGAETTVEIDIA EQFSASGRVIIAKNYLDVYRFETWGGS+I
Sbjct: 411  KVYELVVRHFLACVSQPAIGAETTVEIDIAGEQFSASGRVIIAKNYLDVYRFETWGGSVI 470

Query: 927  PTYNYGQQFTPTTLTLDAGVTRPPPLLSEADLLSCMDKAGIGTDATMHDHIKKLLDRFYA 748
            PTY YGQQFTPTTLTLD+GVTRPPPLLSEADLLSCMDKAGIGTDATMHDHIKKLLDRFYA
Sbjct: 471  PTYTYGQQFTPTTLTLDSGVTRPPPLLSEADLLSCMDKAGIGTDATMHDHIKKLLDRFYA 530

Query: 747  TKDSSMRFSPTKLGEALVMGYDDMGYELWKPYLRAMMESDMKAVSMGTKRKAEVLEACLQ 568
            TKDSSMRFSPTKLGEALVMGYDDMGYELWKPYLRA MESDMKAVSMGTK KAEVLEACLQ
Sbjct: 531  TKDSSMRFSPTKLGEALVMGYDDMGYELWKPYLRAAMESDMKAVSMGTKSKAEVLEACLQ 590

Query: 567  QMKACFVDARLNKGKLFEAMAVFFERSNRSNSNEQHAIGEVVRKCGLCQESDMVLRKKPD 388
            QMKACF+DARLNKGKLFEAMAVFFERSNRSN NE +AIG+V+R+CGLCQESDMVLR+KPD
Sbjct: 591  QMKACFLDARLNKGKLFEAMAVFFERSNRSNGNEPYAIGDVLRRCGLCQESDMVLRRKPD 650

Query: 387  GNFMVGCLGFPQCRNVVWLPGSVSEAIVTTNICSTCSPGPVYLIQFKFRRLEIPPNYNVN 208
            GNFMVGCLG+PQCRNVVWLPGSVSEA VT+NICSTCSPGPVY+IQFKFRRLEIPPNYNV+
Sbjct: 651  GNFMVGCLGYPQCRNVVWLPGSVSEAAVTSNICSTCSPGPVYMIQFKFRRLEIPPNYNVD 710

Query: 207  HLGCIGGCDDILRQLVEVCGTGSRNNSSVPGMYEMHS 97
            HLGCIGGCD+ LRQLVE+CGTGSRNNS++PG  + H+
Sbjct: 711  HLGCIGGCDNTLRQLVEICGTGSRNNSNMPGRGQGHT 747


>ref|XP_006341743.1| PREDICTED: DNA topoisomerase 3-alpha [Solanum tuberosum]
          Length = 915

 Score = 1349 bits (3491), Expect = 0.0
 Identities = 634/751 (84%), Positives = 695/751 (92%)
 Frame = -1

Query: 2367 MAGGGGRPLRALNVAEKPSVAKAVSGILSKTPSSGGLRVRDGRSRYNRIFEFNYTIQNQQ 2188
            MAGGGGR +R LNVAEKPSVAKAVSGILSK    GG+RVRDGRSRYN+IFEFNYTI+NQ 
Sbjct: 1    MAGGGGRVIRVLNVAEKPSVAKAVSGILSKN-QPGGMRVRDGRSRYNKIFEFNYTIRNQP 59

Query: 2187 VHMSFTSVTGHLMELDFEDRYRKWHSCDPVDLYHAPVKKYVPEDKSEIEKTLEEEARKCQ 2008
              M FTSVTGHLMEL+F++RYRKWHSCDP+DLY+APV+K+VPEDK +I++TLE EAR CQ
Sbjct: 60   CQMLFTSVTGHLMELEFDERYRKWHSCDPLDLYNAPVRKFVPEDKLDIKRTLEAEARSCQ 119

Query: 2007 WLILWLDCDREGENIAFEVVEVCTRANRNLNIWRARFSALIDREIHYSVQHLVRPNQLFS 1828
            W++LWLDCDREGENIAFEV++VC +AN NLN+WRARFSALIDREIH SVQ LV+PNQLFS
Sbjct: 120  WIVLWLDCDREGENIAFEVLDVCRQANHNLNVWRARFSALIDREIHQSVQTLVQPNQLFS 179

Query: 1827 DAVDARQEIDLRIGASFTRFQTMLLRDAFVLDFATDNTNVILSYGPCQFPTLGFIVERFW 1648
            DAVD RQEIDLRIGASFTRFQTMLLR AFVLDFATD+ N++LSYGPCQFPTLGF+VER+W
Sbjct: 180  DAVDVRQEIDLRIGASFTRFQTMLLRGAFVLDFATDDRNIVLSYGPCQFPTLGFVVERYW 239

Query: 1647 EVQSHEPEEFWTINCTHNSEEGTATFNWMRGHLFDYTCAMIIYEMCVQEPTATVTNVRQQ 1468
            E+Q+HEPEEFWTINCTHNS+EGTATFNWMRGHLFDYTC + IYEMC+QEP ATVT V+QQ
Sbjct: 240  EIQAHEPEEFWTINCTHNSDEGTATFNWMRGHLFDYTCGVTIYEMCIQEPIATVTKVKQQ 299

Query: 1467 EKLKYPPHPLSTIELEKRASRYFRMSSEHTMKVAEDLYQAGFISYPRTETDCFSVRTDLH 1288
            EKLKYPPHPLSTIELEKRASRYFRMSSE TMKVAEDLYQ GFISYPRTETD FS +TDL 
Sbjct: 300  EKLKYPPHPLSTIELEKRASRYFRMSSEQTMKVAEDLYQNGFISYPRTETDSFSEKTDLR 359

Query: 1287 TIVQEQQGHPVWGSYAQRLLDPEASLWRNPSGGGHDDKAHPPIHPTKFSAGESGWSPDHH 1108
            T+VQEQ+GHPVWG YAQRLLDP++ LWRNPSGGGHDDKAHPPIHPTKFSAGE+ WS DHH
Sbjct: 360  TMVQEQEGHPVWGIYAQRLLDPQSGLWRNPSGGGHDDKAHPPIHPTKFSAGETRWSQDHH 419

Query: 1107 KVYELVVRHFLACVSQPAIGAETTVEIDIACEQFSASGRVIIAKNYLDVYRFETWGGSMI 928
            +VYELVVRHFLACVSQPA+GAET VEIDIA E FSA GRVI+AKNYLDVYRFE+WGGS+I
Sbjct: 420  RVYELVVRHFLACVSQPAVGAETIVEIDIAGESFSACGRVILAKNYLDVYRFESWGGSVI 479

Query: 927  PTYNYGQQFTPTTLTLDAGVTRPPPLLSEADLLSCMDKAGIGTDATMHDHIKKLLDRFYA 748
            PTY++GQQFTPTTLTLD+GVTRPPPLLSEADLL CMDKAGIGTDATMHDHIKKLLDRFYA
Sbjct: 480  PTYSFGQQFTPTTLTLDSGVTRPPPLLSEADLLGCMDKAGIGTDATMHDHIKKLLDRFYA 539

Query: 747  TKDSSMRFSPTKLGEALVMGYDDMGYELWKPYLRAMMESDMKAVSMGTKRKAEVLEACLQ 568
             KDS+ RFSPTKLGEALVMGYDDMGYELWKPYLRAMME DMKAVS+GTKRKAEVLE CLQ
Sbjct: 540  IKDSNTRFSPTKLGEALVMGYDDMGYELWKPYLRAMMECDMKAVSIGTKRKAEVLETCLQ 599

Query: 567  QMKACFVDARLNKGKLFEAMAVFFERSNRSNSNEQHAIGEVVRKCGLCQESDMVLRKKPD 388
            QMKACF DAR NKGKL EAMA+FFERSNRS+  EQ A+G+VVR+CGLC ESDMVLR+KPD
Sbjct: 600  QMKACFSDARTNKGKLLEAMAIFFERSNRSSGGEQQAVGDVVRRCGLCLESDMVLRQKPD 659

Query: 387  GNFMVGCLGFPQCRNVVWLPGSVSEAIVTTNICSTCSPGPVYLIQFKFRRLEIPPNYNVN 208
            GNFMVGCLG+PQCRNVVWLPGSVSEA VT N C++CSPGPV+ IQFKFRRLEIPPNY+V 
Sbjct: 660  GNFMVGCLGYPQCRNVVWLPGSVSEASVTENTCTSCSPGPVFKIQFKFRRLEIPPNYSVQ 719

Query: 207  HLGCIGGCDDILRQLVEVCGTGSRNNSSVPG 115
            HLGCIGGCDDILRQLVE+CGTGSRNNS+  G
Sbjct: 720  HLGCIGGCDDILRQLVEICGTGSRNNSNTSG 750


>ref|XP_015074855.1| PREDICTED: DNA topoisomerase 3-alpha isoform X1 [Solanum pennellii]
          Length = 917

 Score = 1342 bits (3474), Expect = 0.0
 Identities = 632/751 (84%), Positives = 693/751 (92%)
 Frame = -1

Query: 2367 MAGGGGRPLRALNVAEKPSVAKAVSGILSKTPSSGGLRVRDGRSRYNRIFEFNYTIQNQQ 2188
            MAGGGGR +R LNVAEKPSVAKAVSGILSK    GG+RVRDGRSRYN+IFEFNYTI+NQ 
Sbjct: 1    MAGGGGRVIRVLNVAEKPSVAKAVSGILSKN-QPGGIRVRDGRSRYNKIFEFNYTIRNQP 59

Query: 2187 VHMSFTSVTGHLMELDFEDRYRKWHSCDPVDLYHAPVKKYVPEDKSEIEKTLEEEARKCQ 2008
              M FTSVTGHLME++F +RYRKWHSCDP+DLY+APV+K+VPEDK +I++TLE EAR CQ
Sbjct: 60   CQMLFTSVTGHLMEIEFHERYRKWHSCDPLDLYNAPVRKFVPEDKLDIKRTLEAEARSCQ 119

Query: 2007 WLILWLDCDREGENIAFEVVEVCTRANRNLNIWRARFSALIDREIHYSVQHLVRPNQLFS 1828
            W+ILWLDCDREGENIAFEV++VC +AN NL +WRARFSALIDREIH SVQ LV+PNQLFS
Sbjct: 120  WIILWLDCDREGENIAFEVLDVCRQANHNLTVWRARFSALIDREIHQSVQTLVQPNQLFS 179

Query: 1827 DAVDARQEIDLRIGASFTRFQTMLLRDAFVLDFATDNTNVILSYGPCQFPTLGFIVERFW 1648
            DAVD RQEIDLRIGASFTRFQTMLLR AFVLDFATD+ N++LSYGPCQFPTLGF+VER+W
Sbjct: 180  DAVDVRQEIDLRIGASFTRFQTMLLRGAFVLDFATDDRNLVLSYGPCQFPTLGFVVERYW 239

Query: 1647 EVQSHEPEEFWTINCTHNSEEGTATFNWMRGHLFDYTCAMIIYEMCVQEPTATVTNVRQQ 1468
            E+Q+HEPEEFWTINCTHNS+EGTATFNWMRGHLFDYTC ++IYEMC+QEP ATVT V+QQ
Sbjct: 240  EIQAHEPEEFWTINCTHNSDEGTATFNWMRGHLFDYTCGVMIYEMCIQEPIATVTKVKQQ 299

Query: 1467 EKLKYPPHPLSTIELEKRASRYFRMSSEHTMKVAEDLYQAGFISYPRTETDCFSVRTDLH 1288
            EKLKYPPHPLSTIELEKRASRYFRMSSE TMKVAEDLYQ GFISYPRTETDCFS +TDL 
Sbjct: 300  EKLKYPPHPLSTIELEKRASRYFRMSSEQTMKVAEDLYQNGFISYPRTETDCFSDKTDLR 359

Query: 1287 TIVQEQQGHPVWGSYAQRLLDPEASLWRNPSGGGHDDKAHPPIHPTKFSAGESGWSPDHH 1108
            T+VQEQ+GHPVWG+YAQRLLDP++ LWRNPSGGGHDDKAHPPIHPTKFSAGE+ WS DHH
Sbjct: 360  TMVQEQEGHPVWGTYAQRLLDPQSGLWRNPSGGGHDDKAHPPIHPTKFSAGETRWSQDHH 419

Query: 1107 KVYELVVRHFLACVSQPAIGAETTVEIDIACEQFSASGRVIIAKNYLDVYRFETWGGSMI 928
            +VYELVVRHFLACVSQPA+GAET VEIDIA E FSA GRVI+AKNYLDVYRFE+WGGS+I
Sbjct: 420  RVYELVVRHFLACVSQPAVGAETIVEIDIAGESFSACGRVILAKNYLDVYRFESWGGSVI 479

Query: 927  PTYNYGQQFTPTTLTLDAGVTRPPPLLSEADLLSCMDKAGIGTDATMHDHIKKLLDRFYA 748
            PTY++GQQFTPTTLTLD+GVTRPPPLLSEADLL CMDKAGIGTDATMHDHIKKLLDRFYA
Sbjct: 480  PTYSFGQQFTPTTLTLDSGVTRPPPLLSEADLLGCMDKAGIGTDATMHDHIKKLLDRFYA 539

Query: 747  TKDSSMRFSPTKLGEALVMGYDDMGYELWKPYLRAMMESDMKAVSMGTKRKAEVLEACLQ 568
             KDS+ RFSPTKLGEALVMGYDDMGYELWKPYLRAMME DMKAVS GTKRKAEVLE CLQ
Sbjct: 540  IKDSNTRFSPTKLGEALVMGYDDMGYELWKPYLRAMMECDMKAVSTGTKRKAEVLETCLQ 599

Query: 567  QMKACFVDARLNKGKLFEAMAVFFERSNRSNSNEQHAIGEVVRKCGLCQESDMVLRKKPD 388
            QMKACF DAR NKGKL EAMA+FFERSNRS+S EQ A+G VVR+CGLC ESDMVLR+KPD
Sbjct: 600  QMKACFSDARTNKGKLLEAMAIFFERSNRSSSGEQQAVGAVVRRCGLCLESDMVLRQKPD 659

Query: 387  GNFMVGCLGFPQCRNVVWLPGSVSEAIVTTNICSTCSPGPVYLIQFKFRRLEIPPNYNVN 208
            GNFMVGCLG+PQCRNVVWLPGSVSEA VT N C TCSPGPV+ IQFKFR+ EIPP+Y+V 
Sbjct: 660  GNFMVGCLGYPQCRNVVWLPGSVSEASVTENTCITCSPGPVFKIQFKFRQQEIPPDYSVQ 719

Query: 207  HLGCIGGCDDILRQLVEVCGTGSRNNSSVPG 115
            HLGCIGGCDDILRQLVE+CGTGSRN+S+  G
Sbjct: 720  HLGCIGGCDDILRQLVEICGTGSRNSSNTSG 750


>ref|XP_009622049.1| PREDICTED: DNA topoisomerase 3-alpha isoform X1 [Nicotiana
            tomentosiformis]
          Length = 913

 Score = 1338 bits (3462), Expect = 0.0
 Identities = 627/749 (83%), Positives = 691/749 (92%)
 Frame = -1

Query: 2361 GGGGRPLRALNVAEKPSVAKAVSGILSKTPSSGGLRVRDGRSRYNRIFEFNYTIQNQQVH 2182
            GGGGR +R LNVAEKPSVAKAVSGILS+    GG+RVRDGRSRYN+IFEFNYTI+NQ   
Sbjct: 5    GGGGRVIRVLNVAEKPSVAKAVSGILSRN-QGGGMRVRDGRSRYNKIFEFNYTIRNQPCQ 63

Query: 2181 MSFTSVTGHLMELDFEDRYRKWHSCDPVDLYHAPVKKYVPEDKSEIEKTLEEEARKCQWL 2002
            M FTSVTGHLMEL+F+DR+RKWHSCDP+ LY APV+KYVP+DK +I++TLEEEA +CQW+
Sbjct: 64   MLFTSVTGHLMELEFDDRFRKWHSCDPLHLYDAPVRKYVPQDKLDIKRTLEEEASRCQWI 123

Query: 2001 ILWLDCDREGENIAFEVVEVCTRANRNLNIWRARFSALIDREIHYSVQHLVRPNQLFSDA 1822
            ILWLDCDREGENIAFEV+EVC +AN NLN+WRARFSALIDREIH S Q LV+PNQLFSDA
Sbjct: 124  ILWLDCDREGENIAFEVLEVCRQANHNLNVWRARFSALIDREIHQSAQTLVQPNQLFSDA 183

Query: 1821 VDARQEIDLRIGASFTRFQTMLLRDAFVLDFATDNTNVILSYGPCQFPTLGFIVERFWEV 1642
            VD RQEIDLRIGASFTRFQTMLLRDAFVLDFATD+ N++LSYGPCQFPTLGF+VER+WE+
Sbjct: 184  VDVRQEIDLRIGASFTRFQTMLLRDAFVLDFATDDRNLVLSYGPCQFPTLGFVVERYWEI 243

Query: 1641 QSHEPEEFWTINCTHNSEEGTATFNWMRGHLFDYTCAMIIYEMCVQEPTATVTNVRQQEK 1462
            Q+HEPEEFWTINCTHN +EG+ATFNWMRGHLFDYTCA+ IYEMC+QEPTATV+ V+QQEK
Sbjct: 244  QAHEPEEFWTINCTHNFDEGSATFNWMRGHLFDYTCAVTIYEMCIQEPTATVSKVKQQEK 303

Query: 1461 LKYPPHPLSTIELEKRASRYFRMSSEHTMKVAEDLYQAGFISYPRTETDCFSVRTDLHTI 1282
            LKYPPHPLSTIELEKRASRYFRMSSE TMKVAEDLYQ GFISYPRTETDCFS +TDL T+
Sbjct: 304  LKYPPHPLSTIELEKRASRYFRMSSEQTMKVAEDLYQNGFISYPRTETDCFSEKTDLRTM 363

Query: 1281 VQEQQGHPVWGSYAQRLLDPEASLWRNPSGGGHDDKAHPPIHPTKFSAGESGWSPDHHKV 1102
            VQEQ GHPVWGSYAQRLLDP++ LWRNPSGGGHDDKAHPPIHPTKFSAGES WS DHH+V
Sbjct: 364  VQEQGGHPVWGSYAQRLLDPQSGLWRNPSGGGHDDKAHPPIHPTKFSAGESRWSQDHHRV 423

Query: 1101 YELVVRHFLACVSQPAIGAETTVEIDIACEQFSASGRVIIAKNYLDVYRFETWGGSMIPT 922
            YELVVRHFLACVS+PA+GAETTVEIDIA E F A GRVI+AKNYLDVYRFE+WGGS+IPT
Sbjct: 424  YELVVRHFLACVSKPAVGAETTVEIDIAGESFFACGRVILAKNYLDVYRFESWGGSVIPT 483

Query: 921  YNYGQQFTPTTLTLDAGVTRPPPLLSEADLLSCMDKAGIGTDATMHDHIKKLLDRFYATK 742
            Y +GQQF PT+LTLD+GVTRPPPLLSEADLL CMDKAGIGTDATMHDHIKKLLDRFYA K
Sbjct: 484  YTFGQQFIPTSLTLDSGVTRPPPLLSEADLLGCMDKAGIGTDATMHDHIKKLLDRFYAIK 543

Query: 741  DSSMRFSPTKLGEALVMGYDDMGYELWKPYLRAMMESDMKAVSMGTKRKAEVLEACLQQM 562
            DSS RFSPTKLGEALVMGYDDMGYELWKPYLRAMME DMKAVSMGTKRK EVLE CLQQM
Sbjct: 544  DSSTRFSPTKLGEALVMGYDDMGYELWKPYLRAMMECDMKAVSMGTKRKTEVLETCLQQM 603

Query: 561  KACFVDARLNKGKLFEAMAVFFERSNRSNSNEQHAIGEVVRKCGLCQESDMVLRKKPDGN 382
            KACF+DAR NKGKLFEAMA+FFERSNRS+  EQ A+G+VVR+CGLC ESDMVLR+KPDGN
Sbjct: 604  KACFLDARANKGKLFEAMAIFFERSNRSSGGEQQAVGDVVRRCGLCLESDMVLRQKPDGN 663

Query: 381  FMVGCLGFPQCRNVVWLPGSVSEAIVTTNICSTCSPGPVYLIQFKFRRLEIPPNYNVNHL 202
            FMVGCLG+PQCRNVVWLPGS+SEA VT N C++C PGPVY IQF+FRRLEIPPNY+  H+
Sbjct: 664  FMVGCLGYPQCRNVVWLPGSLSEASVTENTCTSCGPGPVYKIQFRFRRLEIPPNYSAQHI 723

Query: 201  GCIGGCDDILRQLVEVCGTGSRNNSSVPG 115
            GCIGGCDDILRQLVE+CGTGSR++S+  G
Sbjct: 724  GCIGGCDDILRQLVEICGTGSRSSSNTFG 752


>ref|XP_010320982.1| PREDICTED: DNA topoisomerase 3-alpha isoform X1 [Solanum
            lycopersicum]
          Length = 915

 Score = 1336 bits (3457), Expect = 0.0
 Identities = 629/751 (83%), Positives = 691/751 (92%)
 Frame = -1

Query: 2367 MAGGGGRPLRALNVAEKPSVAKAVSGILSKTPSSGGLRVRDGRSRYNRIFEFNYTIQNQQ 2188
            MAGGGGR +R LNVAEKPSVAKAVSGILSK    GG+RVRDGRSRYN+IFEFNYTI+NQ 
Sbjct: 1    MAGGGGRVIRVLNVAEKPSVAKAVSGILSKN-QPGGIRVRDGRSRYNKIFEFNYTIRNQP 59

Query: 2187 VHMSFTSVTGHLMELDFEDRYRKWHSCDPVDLYHAPVKKYVPEDKSEIEKTLEEEARKCQ 2008
              M FTSVTGHLME++F +RYRKWHSCDP+DLY+AP++K+VPEDK +I++TLE EAR CQ
Sbjct: 60   CQMLFTSVTGHLMEIEFHERYRKWHSCDPLDLYNAPIRKFVPEDKLDIKRTLEAEARSCQ 119

Query: 2007 WLILWLDCDREGENIAFEVVEVCTRANRNLNIWRARFSALIDREIHYSVQHLVRPNQLFS 1828
            W+ILWLDCDREGENIAFEV++VC +AN NL +WRARFSALIDREIH SVQ LV+PNQLFS
Sbjct: 120  WIILWLDCDREGENIAFEVLDVCRQANHNLTVWRARFSALIDREIHQSVQTLVQPNQLFS 179

Query: 1827 DAVDARQEIDLRIGASFTRFQTMLLRDAFVLDFATDNTNVILSYGPCQFPTLGFIVERFW 1648
            DAVD RQEIDLRIGASFTRFQTMLLR AFVLDFATD+ N++LSYGPCQFPTLGF+VER+W
Sbjct: 180  DAVDVRQEIDLRIGASFTRFQTMLLRGAFVLDFATDDRNLVLSYGPCQFPTLGFVVERYW 239

Query: 1647 EVQSHEPEEFWTINCTHNSEEGTATFNWMRGHLFDYTCAMIIYEMCVQEPTATVTNVRQQ 1468
            E+Q+HEPEEFWTINCTHNS+EGTATFNWMRGHLFDYTC ++IYEMC+QEP ATVT V+QQ
Sbjct: 240  EIQAHEPEEFWTINCTHNSDEGTATFNWMRGHLFDYTCGVMIYEMCIQEPIATVTKVKQQ 299

Query: 1467 EKLKYPPHPLSTIELEKRASRYFRMSSEHTMKVAEDLYQAGFISYPRTETDCFSVRTDLH 1288
            EKLKYPPHPLSTIELEKRASRYFRMSSE TMKVAEDLYQ GFISYPRTETDCFS +TDL 
Sbjct: 300  EKLKYPPHPLSTIELEKRASRYFRMSSEQTMKVAEDLYQNGFISYPRTETDCFSDKTDLR 359

Query: 1287 TIVQEQQGHPVWGSYAQRLLDPEASLWRNPSGGGHDDKAHPPIHPTKFSAGESGWSPDHH 1108
            T+VQEQ+GHPVWG+YAQRLLDP++ LWRNPSGGGHDDKAHPPIHPTKFSAGE+ WS DHH
Sbjct: 360  TMVQEQEGHPVWGTYAQRLLDPQSGLWRNPSGGGHDDKAHPPIHPTKFSAGETRWSQDHH 419

Query: 1107 KVYELVVRHFLACVSQPAIGAETTVEIDIACEQFSASGRVIIAKNYLDVYRFETWGGSMI 928
            +VYELVVRHFLACVSQPA+GAET VEIDIA E FSA GRVI+AKNYLDVYRFE+WGGS+I
Sbjct: 420  RVYELVVRHFLACVSQPAVGAETIVEIDIAGESFSACGRVILAKNYLDVYRFESWGGSVI 479

Query: 927  PTYNYGQQFTPTTLTLDAGVTRPPPLLSEADLLSCMDKAGIGTDATMHDHIKKLLDRFYA 748
            PTY++GQQFTPTTLTLD+GV RPPPLLSEADLL CMDKAGIGTDATMHDHIKKLLDRFYA
Sbjct: 480  PTYSFGQQFTPTTLTLDSGVIRPPPLLSEADLLGCMDKAGIGTDATMHDHIKKLLDRFYA 539

Query: 747  TKDSSMRFSPTKLGEALVMGYDDMGYELWKPYLRAMMESDMKAVSMGTKRKAEVLEACLQ 568
             KDS+ RFSPTKLGEALVMGYDDMGYELWKPYLRAMME DMKAVS GTKRKAEVLE CLQ
Sbjct: 540  IKDSNTRFSPTKLGEALVMGYDDMGYELWKPYLRAMMECDMKAVSTGTKRKAEVLETCLQ 599

Query: 567  QMKACFVDARLNKGKLFEAMAVFFERSNRSNSNEQHAIGEVVRKCGLCQESDMVLRKKPD 388
            QMKACF DAR NK KL EAMA+FFERSNRS+S EQ A+G VVR+CGLC ESDMVLR+KPD
Sbjct: 600  QMKACFSDARTNKEKLLEAMAIFFERSNRSSSGEQQAVGAVVRRCGLCLESDMVLRQKPD 659

Query: 387  GNFMVGCLGFPQCRNVVWLPGSVSEAIVTTNICSTCSPGPVYLIQFKFRRLEIPPNYNVN 208
            GNFMVGCLG+PQCRNVVWLPGSVSEA VT N C TCSPGPV+ IQFKFR+ EIPP+Y+V 
Sbjct: 660  GNFMVGCLGYPQCRNVVWLPGSVSEASVTENTCITCSPGPVFKIQFKFRQQEIPPDYSVQ 719

Query: 207  HLGCIGGCDDILRQLVEVCGTGSRNNSSVPG 115
            HLGCIGGCDDILRQLVE+CGTGSRN+S+  G
Sbjct: 720  HLGCIGGCDDILRQLVEICGTGSRNSSNPSG 750


>ref|XP_010649354.1| PREDICTED: DNA topoisomerase 3-alpha isoform X2 [Vitis vinifera]
          Length = 918

 Score = 1301 bits (3366), Expect = 0.0
 Identities = 610/742 (82%), Positives = 680/742 (91%)
 Frame = -1

Query: 2343 LRALNVAEKPSVAKAVSGILSKTPSSGGLRVRDGRSRYNRIFEFNYTIQNQQVHMSFTSV 2164
            ++ LNVAEKPSVAKAV+ ILS+     GLRVR+GRSRYN++FEFNY+I+ Q   M  TSV
Sbjct: 1    MKVLNVAEKPSVAKAVATILSRNQ---GLRVREGRSRYNKLFEFNYSIRGQHCQMVVTSV 57

Query: 2163 TGHLMELDFEDRYRKWHSCDPVDLYHAPVKKYVPEDKSEIEKTLEEEARKCQWLILWLDC 1984
             GHLMEL+FEDR+RKWHSCDP  LYHAPV+K+VPEDK +I++TLEEEARKCQWL+LWLDC
Sbjct: 58   IGHLMELEFEDRFRKWHSCDPAHLYHAPVRKFVPEDKLDIKRTLEEEARKCQWLVLWLDC 117

Query: 1983 DREGENIAFEVVEVCTRANRNLNIWRARFSALIDREIHYSVQHLVRPNQLFSDAVDARQE 1804
            DREGENIAFEV+EVC + NR++++WRARFSALIDREIH SVQ+LVRPNQLF+DAVD RQE
Sbjct: 118  DREGENIAFEVLEVCAQVNRHIDVWRARFSALIDREIHESVQNLVRPNQLFADAVDVRQE 177

Query: 1803 IDLRIGASFTRFQTMLLRDAFVLDFATDNTNVILSYGPCQFPTLGFIVERFWEVQSHEPE 1624
            IDLRIGASFTRFQTMLLRDAFVLDFA D+ N++LSYGPCQFPTLGF+VER+WE+QSHEPE
Sbjct: 178  IDLRIGASFTRFQTMLLRDAFVLDFAADDRNLVLSYGPCQFPTLGFVVERYWEIQSHEPE 237

Query: 1623 EFWTINCTHNSEEGTATFNWMRGHLFDYTCAMIIYEMCVQEPTATVTNVRQQEKLKYPPH 1444
            EFWTINC+H S+EGT+TFNWMR HLFDYTCA+IIYEMC+QEPTATVT VRQQEKLKYPPH
Sbjct: 238  EFWTINCSHKSDEGTSTFNWMRAHLFDYTCAVIIYEMCIQEPTATVTKVRQQEKLKYPPH 297

Query: 1443 PLSTIELEKRASRYFRMSSEHTMKVAEDLYQAGFISYPRTETDCFSVRTDLHTIVQEQQG 1264
            PL+TIELEKRASRYF MSSEHTMKVAEDLYQ GFISYPRTETD FS RTDLH IVQEQ G
Sbjct: 298  PLNTIELEKRASRYFHMSSEHTMKVAEDLYQTGFISYPRTETDYFSERTDLHGIVQEQLG 357

Query: 1263 HPVWGSYAQRLLDPEASLWRNPSGGGHDDKAHPPIHPTKFSAGESGWSPDHHKVYELVVR 1084
            HP+WGSYAQRLLDP A LWRNPS GGHDDKAHPPIHPTKFSAGESGWS DH ++YELVVR
Sbjct: 358  HPIWGSYAQRLLDPGAGLWRNPSNGGHDDKAHPPIHPTKFSAGESGWSQDHQRLYELVVR 417

Query: 1083 HFLACVSQPAIGAETTVEIDIACEQFSASGRVIIAKNYLDVYRFETWGGSMIPTYNYGQQ 904
            HFLACVSQPA+GAET VEIDIA E FS+SGRVIIAKNYLDVYRFE+WGGSMIPTY +GQQ
Sbjct: 418  HFLACVSQPAVGAETIVEIDIAGESFSSSGRVIIAKNYLDVYRFESWGGSMIPTYVFGQQ 477

Query: 903  FTPTTLTLDAGVTRPPPLLSEADLLSCMDKAGIGTDATMHDHIKKLLDRFYATKDSSMRF 724
            F PTTLTLD+GVTRPPPLLSEADLL+CMDKAGIGTDATMHDHIKKLLDRFYATKDS+ RF
Sbjct: 478  FIPTTLTLDSGVTRPPPLLSEADLLNCMDKAGIGTDATMHDHIKKLLDRFYATKDSNTRF 537

Query: 723  SPTKLGEALVMGYDDMGYELWKPYLRAMMESDMKAVSMGTKRKAEVLEACLQQMKACFVD 544
            SPT LGEALVMGYDDMGYELWKPYLR+MME DMKAVS+GTKR+ EVL  CL+QMKACF+D
Sbjct: 538  SPTNLGEALVMGYDDMGYELWKPYLRSMMECDMKAVSIGTKRRNEVLTTCLEQMKACFLD 597

Query: 543  ARLNKGKLFEAMAVFFERSNRSNSNEQHAIGEVVRKCGLCQESDMVLRKKPDGNFMVGCL 364
            ARLNK KL EAMA+FFERSNRS+ +EQH +G+VVR+C LCQESDMVLR+KPDGNFMVGCL
Sbjct: 598  ARLNKVKLLEAMALFFERSNRSSGDEQHEVGDVVRQCTLCQESDMVLRRKPDGNFMVGCL 657

Query: 363  GFPQCRNVVWLPGSVSEAIVTTNICSTCSPGPVYLIQFKFRRLEIPPNYNVNHLGCIGGC 184
            G+PQCRNVVWLPGS+SEA +TT  C+ C+PGPVY IQFKFRRLEIPPNYN++HLGC+ GC
Sbjct: 658  GYPQCRNVVWLPGSISEAAITTISCNHCTPGPVYKIQFKFRRLEIPPNYNIDHLGCVCGC 717

Query: 183  DDILRQLVEVCGTGSRNNSSVP 118
            D+ILRQL E+CGTGSR  S+VP
Sbjct: 718  DEILRQLTEICGTGSRICSTVP 739


>ref|XP_010649353.1| PREDICTED: DNA topoisomerase 3-alpha isoform X1 [Vitis vinifera]
          Length = 919

 Score = 1301 bits (3366), Expect = 0.0
 Identities = 610/742 (82%), Positives = 680/742 (91%)
 Frame = -1

Query: 2343 LRALNVAEKPSVAKAVSGILSKTPSSGGLRVRDGRSRYNRIFEFNYTIQNQQVHMSFTSV 2164
            ++ LNVAEKPSVAKAV+ ILS+     GLRVR+GRSRYN++FEFNY+I+ Q   M  TSV
Sbjct: 1    MKVLNVAEKPSVAKAVATILSRNQ---GLRVREGRSRYNKLFEFNYSIRGQHCQMVVTSV 57

Query: 2163 TGHLMELDFEDRYRKWHSCDPVDLYHAPVKKYVPEDKSEIEKTLEEEARKCQWLILWLDC 1984
             GHLMEL+FEDR+RKWHSCDP  LYHAPV+K+VPEDK +I++TLEEEARKCQWL+LWLDC
Sbjct: 58   IGHLMELEFEDRFRKWHSCDPAHLYHAPVRKFVPEDKLDIKRTLEEEARKCQWLVLWLDC 117

Query: 1983 DREGENIAFEVVEVCTRANRNLNIWRARFSALIDREIHYSVQHLVRPNQLFSDAVDARQE 1804
            DREGENIAFEV+EVC + NR++++WRARFSALIDREIH SVQ+LVRPNQLF+DAVD RQE
Sbjct: 118  DREGENIAFEVLEVCAQVNRHIDVWRARFSALIDREIHESVQNLVRPNQLFADAVDVRQE 177

Query: 1803 IDLRIGASFTRFQTMLLRDAFVLDFATDNTNVILSYGPCQFPTLGFIVERFWEVQSHEPE 1624
            IDLRIGASFTRFQTMLLRDAFVLDFA D+ N++LSYGPCQFPTLGF+VER+WE+QSHEPE
Sbjct: 178  IDLRIGASFTRFQTMLLRDAFVLDFAADDRNLVLSYGPCQFPTLGFVVERYWEIQSHEPE 237

Query: 1623 EFWTINCTHNSEEGTATFNWMRGHLFDYTCAMIIYEMCVQEPTATVTNVRQQEKLKYPPH 1444
            EFWTINC+H S+EGT+TFNWMR HLFDYTCA+IIYEMC+QEPTATVT VRQQEKLKYPPH
Sbjct: 238  EFWTINCSHKSDEGTSTFNWMRAHLFDYTCAVIIYEMCIQEPTATVTKVRQQEKLKYPPH 297

Query: 1443 PLSTIELEKRASRYFRMSSEHTMKVAEDLYQAGFISYPRTETDCFSVRTDLHTIVQEQQG 1264
            PL+TIELEKRASRYF MSSEHTMKVAEDLYQ GFISYPRTETD FS RTDLH IVQEQ G
Sbjct: 298  PLNTIELEKRASRYFHMSSEHTMKVAEDLYQTGFISYPRTETDYFSERTDLHGIVQEQLG 357

Query: 1263 HPVWGSYAQRLLDPEASLWRNPSGGGHDDKAHPPIHPTKFSAGESGWSPDHHKVYELVVR 1084
            HP+WGSYAQRLLDP A LWRNPS GGHDDKAHPPIHPTKFSAGESGWS DH ++YELVVR
Sbjct: 358  HPIWGSYAQRLLDPGAGLWRNPSNGGHDDKAHPPIHPTKFSAGESGWSQDHQRLYELVVR 417

Query: 1083 HFLACVSQPAIGAETTVEIDIACEQFSASGRVIIAKNYLDVYRFETWGGSMIPTYNYGQQ 904
            HFLACVSQPA+GAET VEIDIA E FS+SGRVIIAKNYLDVYRFE+WGGSMIPTY +GQQ
Sbjct: 418  HFLACVSQPAVGAETIVEIDIAGESFSSSGRVIIAKNYLDVYRFESWGGSMIPTYVFGQQ 477

Query: 903  FTPTTLTLDAGVTRPPPLLSEADLLSCMDKAGIGTDATMHDHIKKLLDRFYATKDSSMRF 724
            F PTTLTLD+GVTRPPPLLSEADLL+CMDKAGIGTDATMHDHIKKLLDRFYATKDS+ RF
Sbjct: 478  FIPTTLTLDSGVTRPPPLLSEADLLNCMDKAGIGTDATMHDHIKKLLDRFYATKDSNTRF 537

Query: 723  SPTKLGEALVMGYDDMGYELWKPYLRAMMESDMKAVSMGTKRKAEVLEACLQQMKACFVD 544
            SPT LGEALVMGYDDMGYELWKPYLR+MME DMKAVS+GTKR+ EVL  CL+QMKACF+D
Sbjct: 538  SPTNLGEALVMGYDDMGYELWKPYLRSMMECDMKAVSIGTKRRNEVLTTCLEQMKACFLD 597

Query: 543  ARLNKGKLFEAMAVFFERSNRSNSNEQHAIGEVVRKCGLCQESDMVLRKKPDGNFMVGCL 364
            ARLNK KL EAMA+FFERSNRS+ +EQH +G+VVR+C LCQESDMVLR+KPDGNFMVGCL
Sbjct: 598  ARLNKVKLLEAMALFFERSNRSSGDEQHEVGDVVRQCTLCQESDMVLRRKPDGNFMVGCL 657

Query: 363  GFPQCRNVVWLPGSVSEAIVTTNICSTCSPGPVYLIQFKFRRLEIPPNYNVNHLGCIGGC 184
            G+PQCRNVVWLPGS+SEA +TT  C+ C+PGPVY IQFKFRRLEIPPNYN++HLGC+ GC
Sbjct: 658  GYPQCRNVVWLPGSISEAAITTISCNHCTPGPVYKIQFKFRRLEIPPNYNIDHLGCVCGC 717

Query: 183  DDILRQLVEVCGTGSRNNSSVP 118
            D+ILRQL E+CGTGSR  S+VP
Sbjct: 718  DEILRQLTEICGTGSRICSTVP 739


>ref|XP_009622050.1| PREDICTED: DNA topoisomerase 3-alpha isoform X2 [Nicotiana
            tomentosiformis]
          Length = 900

 Score = 1300 bits (3365), Expect = 0.0
 Identities = 615/749 (82%), Positives = 678/749 (90%)
 Frame = -1

Query: 2361 GGGGRPLRALNVAEKPSVAKAVSGILSKTPSSGGLRVRDGRSRYNRIFEFNYTIQNQQVH 2182
            GGGGR +R LNVAEKPSVAKAVSGILS+    GG+RVRDGRSRYN+IFEFNYTI+NQ   
Sbjct: 5    GGGGRVIRVLNVAEKPSVAKAVSGILSRN-QGGGMRVRDGRSRYNKIFEFNYTIRNQPCQ 63

Query: 2181 MSFTSVTGHLMELDFEDRYRKWHSCDPVDLYHAPVKKYVPEDKSEIEKTLEEEARKCQWL 2002
            M FTSVTGHLMEL+F+DR+RKWHSCDP+ LY APV+KYVP+DK +I++TLEEEA +CQW+
Sbjct: 64   MLFTSVTGHLMELEFDDRFRKWHSCDPLHLYDAPVRKYVPQDKLDIKRTLEEEASRCQWI 123

Query: 2001 ILWLDCDREGENIAFEVVEVCTRANRNLNIWRARFSALIDREIHYSVQHLVRPNQLFSDA 1822
            ILWLDCDREGENIAFEV+EVC +AN NLN+WRARFSALIDREIH S Q LV+PNQLFSDA
Sbjct: 124  ILWLDCDREGENIAFEVLEVCRQANHNLNVWRARFSALIDREIHQSAQTLVQPNQLFSDA 183

Query: 1821 VDARQEIDLRIGASFTRFQTMLLRDAFVLDFATDNTNVILSYGPCQFPTLGFIVERFWEV 1642
            VD RQEIDLRIGASFTRFQTMLLRDAFVLDFATD+ N++LSYGPCQFPTLGF+VER+WE+
Sbjct: 184  VDVRQEIDLRIGASFTRFQTMLLRDAFVLDFATDDRNLVLSYGPCQFPTLGFVVERYWEI 243

Query: 1641 QSHEPEEFWTINCTHNSEEGTATFNWMRGHLFDYTCAMIIYEMCVQEPTATVTNVRQQEK 1462
            Q+HEPEEFWTINCTHN +EG+ATFNWMRGHLFDYTCA+ IYEMC+QEPTATV+ V+QQEK
Sbjct: 244  QAHEPEEFWTINCTHNFDEGSATFNWMRGHLFDYTCAVTIYEMCIQEPTATVSKVKQQEK 303

Query: 1461 LKYPPHPLSTIELEKRASRYFRMSSEHTMKVAEDLYQAGFISYPRTETDCFSVRTDLHTI 1282
            LKYPPHPLSTIELEKRASRYFRMSSE TMKVAEDLYQ GFISYPRTETDCFS +TDL T+
Sbjct: 304  LKYPPHPLSTIELEKRASRYFRMSSEQTMKVAEDLYQNGFISYPRTETDCFSEKTDLRTM 363

Query: 1281 VQEQQGHPVWGSYAQRLLDPEASLWRNPSGGGHDDKAHPPIHPTKFSAGESGWSPDHHKV 1102
            VQEQ GHPVWGSYAQRLLDP++ LWRNPSGGGHDDKAHPPIHPTKFSAGES WS DHH+V
Sbjct: 364  VQEQGGHPVWGSYAQRLLDPQSGLWRNPSGGGHDDKAHPPIHPTKFSAGESRWSQDHHRV 423

Query: 1101 YELVVRHFLACVSQPAIGAETTVEIDIACEQFSASGRVIIAKNYLDVYRFETWGGSMIPT 922
            YELVVRHFLACVS+PA+GAETTVEIDIA E F A GRVI+AKNYLDVYRFE+WGGS+IPT
Sbjct: 424  YELVVRHFLACVSKPAVGAETTVEIDIAGESFFACGRVILAKNYLDVYRFESWGGSVIPT 483

Query: 921  YNYGQQFTPTTLTLDAGVTRPPPLLSEADLLSCMDKAGIGTDATMHDHIKKLLDRFYATK 742
            Y +GQQF PT+LTLD+GVTRPPPLLSEADLL CMDKAGIGTDATMHDHIKKLLDRFYA K
Sbjct: 484  YTFGQQFIPTSLTLDSGVTRPPPLLSEADLLGCMDKAGIGTDATMHDHIKKLLDRFYAIK 543

Query: 741  DSSMRFSPTKLGEALVMGYDDMGYELWKPYLRAMMESDMKAVSMGTKRKAEVLEACLQQM 562
            DSS RFSPTKLGEALVMGYDDMGYELWKPYLRAMME DMKAVSMGTKRK EVLE CLQQM
Sbjct: 544  DSSTRFSPTKLGEALVMGYDDMGYELWKPYLRAMMECDMKAVSMGTKRKTEVLETCLQQM 603

Query: 561  KACFVDARLNKGKLFEAMAVFFERSNRSNSNEQHAIGEVVRKCGLCQESDMVLRKKPDGN 382
            KACF+DAR NKGKLFEAMA+FFERSNRS+  EQ A+G+VVR+CGLC ESDMVLR+KP   
Sbjct: 604  KACFLDARANKGKLFEAMAIFFERSNRSSGGEQQAVGDVVRRCGLCLESDMVLRQKP--- 660

Query: 381  FMVGCLGFPQCRNVVWLPGSVSEAIVTTNICSTCSPGPVYLIQFKFRRLEIPPNYNVNHL 202
                      CRNVVWLPGS+SEA VT N C++C PGPVY IQF+FRRLEIPPNY+  H+
Sbjct: 661  ----------CRNVVWLPGSLSEASVTENTCTSCGPGPVYKIQFRFRRLEIPPNYSAQHI 710

Query: 201  GCIGGCDDILRQLVEVCGTGSRNNSSVPG 115
            GCIGGCDDILRQLVE+CGTGSR++S+  G
Sbjct: 711  GCIGGCDDILRQLVEICGTGSRSSSNTFG 739


>ref|XP_010270299.1| PREDICTED: DNA topoisomerase 3-alpha [Nelumbo nucifera]
          Length = 921

 Score = 1298 bits (3358), Expect = 0.0
 Identities = 608/743 (81%), Positives = 679/743 (91%)
 Frame = -1

Query: 2352 GRPLRALNVAEKPSVAKAVSGILSKTPSSGGLRVRDGRSRYNRIFEFNYTIQNQQVHMSF 2173
            GR +R LNVAEKPSVAKAV+GILS+     GLRVR+GRSR+NRIFEF+Y+I+ Q  HM F
Sbjct: 4    GRTVRVLNVAEKPSVAKAVAGILSRNQ---GLRVRNGRSRFNRIFEFDYSIRGQHCHMLF 60

Query: 2172 TSVTGHLMELDFEDRYRKWHSCDPVDLYHAPVKKYVPEDKSEIEKTLEEEARKCQWLILW 1993
            TSVTGHLMEL+FE+RYRKWHSCDP DLYHAPV+K+VP+DK +I++TLEEEARKCQWL+LW
Sbjct: 61   TSVTGHLMELEFEERYRKWHSCDPADLYHAPVRKFVPQDKLDIKRTLEEEARKCQWLVLW 120

Query: 1992 LDCDREGENIAFEVVEVCTRANRNLNIWRARFSALIDREIHYSVQHLVRPNQLFSDAVDA 1813
            LDCDREGENIAFEVVE+C+ AN +LNIWRARFSALIDREIH SVQ+LVRPNQLF+DAVDA
Sbjct: 121  LDCDREGENIAFEVVEICSAANNHLNIWRARFSALIDREIHESVQNLVRPNQLFADAVDA 180

Query: 1812 RQEIDLRIGASFTRFQTMLLRDAFVLDFATDNTNVILSYGPCQFPTLGFIVERFWEVQSH 1633
            RQEIDLRIGASFTRFQTMLL+DAFV+DFATD+ N++LSYGPCQFPTLGF+VER+WE+Q+H
Sbjct: 181  RQEIDLRIGASFTRFQTMLLKDAFVIDFATDDRNLVLSYGPCQFPTLGFVVERYWEIQAH 240

Query: 1632 EPEEFWTINCTHNSEEGTATFNWMRGHLFDYTCAMIIYEMCVQEPTATVTNVRQQEKLKY 1453
            EPEEFWTINC+H  +EG ATFNWMRGH+FDYT A+IIYEMC  EPTATVT V+ QEKLKY
Sbjct: 241  EPEEFWTINCSHTLDEGIATFNWMRGHIFDYTYAVIIYEMCTLEPTATVTKVKNQEKLKY 300

Query: 1452 PPHPLSTIELEKRASRYFRMSSEHTMKVAEDLYQAGFISYPRTETDCFSVRTDLHTIVQE 1273
            PPHPL+TIELEKRASRYFRMSSEHTMKVAE+LYQ+GFISYPRTETDCFS RTDLH +VQE
Sbjct: 301  PPHPLNTIELEKRASRYFRMSSEHTMKVAEELYQSGFISYPRTETDCFSARTDLHAMVQE 360

Query: 1272 QQGHPVWGSYAQRLLDPEASLWRNPSGGGHDDKAHPPIHPTKFSAGESGWSPDHHKVYEL 1093
            QQGHP+WGSYAQRLLDPEA LWR+PS GGHDDKAHPPIHPTK+SAGESGWS DHH++YEL
Sbjct: 361  QQGHPLWGSYAQRLLDPEARLWRSPSNGGHDDKAHPPIHPTKYSAGESGWSQDHHRLYEL 420

Query: 1092 VVRHFLACVSQPAIGAETTVEIDIACEQFSASGRVIIAKNYLDVYRFETWGGSMIPTYNY 913
            VVRHFLACVSQPAIGAET VEIDIA EQFS SGRVI+ KNYLDVYRFE+WGGSMIPTY+ 
Sbjct: 421  VVRHFLACVSQPAIGAETIVEIDIAGEQFSVSGRVILQKNYLDVYRFESWGGSMIPTYSV 480

Query: 912  GQQFTPTTLTLDAGVTRPPPLLSEADLLSCMDKAGIGTDATMHDHIKKLLDRFYATKDSS 733
            GQQF PT LTLD+GVTRPPPLLSEADLL+CMDKAGIGTDATMHDHIKKLLDR YATKDS+
Sbjct: 481  GQQFIPTALTLDSGVTRPPPLLSEADLLNCMDKAGIGTDATMHDHIKKLLDRCYATKDSN 540

Query: 732  MRFSPTKLGEALVMGYDDMGYELWKPYLRAMMESDMKAVSMGTKRKAEVLEACLQQMKAC 553
             RFSPT LGEALVMGYDDMGYELWKPYLR+MME DMKAVS+GTKRKAEVLE CLQQMKAC
Sbjct: 541  TRFSPTNLGEALVMGYDDMGYELWKPYLRSMMECDMKAVSIGTKRKAEVLETCLQQMKAC 600

Query: 552  FVDARLNKGKLFEAMAVFFERSNRSNSNEQHAIGEVVRKCGLCQESDMVLRKKPDGNFMV 373
            F+DARLNK KL EAMA+FFER NR  +NEQ    ++VR C  CQES+MVL++KPDGNFMV
Sbjct: 601  FLDARLNKVKLLEAMAIFFERCNRPGTNEQQGAVDIVRPCSACQESNMVLKRKPDGNFMV 660

Query: 372  GCLGFPQCRNVVWLPGSVSEAIVTTNICSTCSPGPVYLIQFKFRRLEIPPNYNVNHLGCI 193
            GCLGFPQCRNVVWLPGS+S A VT +IC +CSPGPV+ IQFKFRRLEIP +Y+V+HLGCI
Sbjct: 661  GCLGFPQCRNVVWLPGSISTATVTNHICDSCSPGPVFKIQFKFRRLEIPSDYDVDHLGCI 720

Query: 192  GGCDDILRQLVEVCGTGSRNNSS 124
            GGCD+ L+QL E+CGTGSRN  S
Sbjct: 721  GGCDETLKQLTEICGTGSRNPPS 743


>ref|XP_015074856.1| PREDICTED: DNA topoisomerase 3-alpha isoform X2 [Solanum pennellii]
          Length = 746

 Score = 1291 bits (3342), Expect = 0.0
 Identities = 609/723 (84%), Positives = 667/723 (92%)
 Frame = -1

Query: 2367 MAGGGGRPLRALNVAEKPSVAKAVSGILSKTPSSGGLRVRDGRSRYNRIFEFNYTIQNQQ 2188
            MAGGGGR +R LNVAEKPSVAKAVSGILSK    GG+RVRDGRSRYN+IFEFNYTI+NQ 
Sbjct: 1    MAGGGGRVIRVLNVAEKPSVAKAVSGILSKN-QPGGIRVRDGRSRYNKIFEFNYTIRNQP 59

Query: 2187 VHMSFTSVTGHLMELDFEDRYRKWHSCDPVDLYHAPVKKYVPEDKSEIEKTLEEEARKCQ 2008
              M FTSVTGHLME++F +RYRKWHSCDP+DLY+APV+K+VPEDK +I++TLE EAR CQ
Sbjct: 60   CQMLFTSVTGHLMEIEFHERYRKWHSCDPLDLYNAPVRKFVPEDKLDIKRTLEAEARSCQ 119

Query: 2007 WLILWLDCDREGENIAFEVVEVCTRANRNLNIWRARFSALIDREIHYSVQHLVRPNQLFS 1828
            W+ILWLDCDREGENIAFEV++VC +AN NL +WRARFSALIDREIH SVQ LV+PNQLFS
Sbjct: 120  WIILWLDCDREGENIAFEVLDVCRQANHNLTVWRARFSALIDREIHQSVQTLVQPNQLFS 179

Query: 1827 DAVDARQEIDLRIGASFTRFQTMLLRDAFVLDFATDNTNVILSYGPCQFPTLGFIVERFW 1648
            DAVD RQEIDLRIGASFTRFQTMLLR AFVLDFATD+ N++LSYGPCQFPTLGF+VER+W
Sbjct: 180  DAVDVRQEIDLRIGASFTRFQTMLLRGAFVLDFATDDRNLVLSYGPCQFPTLGFVVERYW 239

Query: 1647 EVQSHEPEEFWTINCTHNSEEGTATFNWMRGHLFDYTCAMIIYEMCVQEPTATVTNVRQQ 1468
            E+Q+HEPEEFWTINCTHNS+EGTATFNWMRGHLFDYTC ++IYEMC+QEP ATVT V+QQ
Sbjct: 240  EIQAHEPEEFWTINCTHNSDEGTATFNWMRGHLFDYTCGVMIYEMCIQEPIATVTKVKQQ 299

Query: 1467 EKLKYPPHPLSTIELEKRASRYFRMSSEHTMKVAEDLYQAGFISYPRTETDCFSVRTDLH 1288
            EKLKYPPHPLSTIELEKRASRYFRMSSE TMKVAEDLYQ GFISYPRTETDCFS +TDL 
Sbjct: 300  EKLKYPPHPLSTIELEKRASRYFRMSSEQTMKVAEDLYQNGFISYPRTETDCFSDKTDLR 359

Query: 1287 TIVQEQQGHPVWGSYAQRLLDPEASLWRNPSGGGHDDKAHPPIHPTKFSAGESGWSPDHH 1108
            T+VQEQ+GHPVWG+YAQRLLDP++ LWRNPSGGGHDDKAHPPIHPTKFSAGE+ WS DHH
Sbjct: 360  TMVQEQEGHPVWGTYAQRLLDPQSGLWRNPSGGGHDDKAHPPIHPTKFSAGETRWSQDHH 419

Query: 1107 KVYELVVRHFLACVSQPAIGAETTVEIDIACEQFSASGRVIIAKNYLDVYRFETWGGSMI 928
            +VYELVVRHFLACVSQPA+GAET VEIDIA E FSA GRVI+AKNYLDVYRFE+WGGS+I
Sbjct: 420  RVYELVVRHFLACVSQPAVGAETIVEIDIAGESFSACGRVILAKNYLDVYRFESWGGSVI 479

Query: 927  PTYNYGQQFTPTTLTLDAGVTRPPPLLSEADLLSCMDKAGIGTDATMHDHIKKLLDRFYA 748
            PTY++GQQFTPTTLTLD+GVTRPPPLLSEADLL CMDKAGIGTDATMHDHIKKLLDRFYA
Sbjct: 480  PTYSFGQQFTPTTLTLDSGVTRPPPLLSEADLLGCMDKAGIGTDATMHDHIKKLLDRFYA 539

Query: 747  TKDSSMRFSPTKLGEALVMGYDDMGYELWKPYLRAMMESDMKAVSMGTKRKAEVLEACLQ 568
             KDS+ RFSPTKLGEALVMGYDDMGYELWKPYLRAMME DMKAVS GTKRKAEVLE CLQ
Sbjct: 540  IKDSNTRFSPTKLGEALVMGYDDMGYELWKPYLRAMMECDMKAVSTGTKRKAEVLETCLQ 599

Query: 567  QMKACFVDARLNKGKLFEAMAVFFERSNRSNSNEQHAIGEVVRKCGLCQESDMVLRKKPD 388
            QMKACF DAR NKGKL EAMA+FFERSNRS+S EQ A+G VVR+CGLC ESDMVLR+KPD
Sbjct: 600  QMKACFSDARTNKGKLLEAMAIFFERSNRSSSGEQQAVGAVVRRCGLCLESDMVLRQKPD 659

Query: 387  GNFMVGCLGFPQCRNVVWLPGSVSEAIVTTNICSTCSPGPVYLIQFKFRRLEIPPNYNVN 208
            GNFMVGCLG+PQCRNVVWLPGSVSEA VT N C TCSPGPV+ IQFKFR+ EIPP+Y+V 
Sbjct: 660  GNFMVGCLGYPQCRNVVWLPGSVSEASVTENTCITCSPGPVFKIQFKFRQQEIPPDYSVQ 719

Query: 207  HLG 199
            HLG
Sbjct: 720  HLG 722


>ref|XP_010649355.1| PREDICTED: DNA topoisomerase 3-alpha isoform X3 [Vitis vinifera]
          Length = 916

 Score = 1290 bits (3337), Expect = 0.0
 Identities = 607/742 (81%), Positives = 677/742 (91%)
 Frame = -1

Query: 2343 LRALNVAEKPSVAKAVSGILSKTPSSGGLRVRDGRSRYNRIFEFNYTIQNQQVHMSFTSV 2164
            ++ LNVAEKPSVAKAV+ ILS+     GLRVR+GRSRYN++FEFNY+I+ Q   M  TSV
Sbjct: 1    MKVLNVAEKPSVAKAVATILSRNQ---GLRVREGRSRYNKLFEFNYSIRGQHCQMVVTSV 57

Query: 2163 TGHLMELDFEDRYRKWHSCDPVDLYHAPVKKYVPEDKSEIEKTLEEEARKCQWLILWLDC 1984
             GHLMEL+FEDR+RKWHSCDP  LYHAPV+K+VPEDK +I++TLEEEARKCQWL+LWLDC
Sbjct: 58   IGHLMELEFEDRFRKWHSCDPAHLYHAPVRKFVPEDKLDIKRTLEEEARKCQWLVLWLDC 117

Query: 1983 DREGENIAFEVVEVCTRANRNLNIWRARFSALIDREIHYSVQHLVRPNQLFSDAVDARQE 1804
            DREGENIAFEV+EVC + NR++++WRARFSALIDREIH SVQ+LVRPNQLF+DAVD RQE
Sbjct: 118  DREGENIAFEVLEVCAQVNRHIDVWRARFSALIDREIHESVQNLVRPNQLFADAVDVRQE 177

Query: 1803 IDLRIGASFTRFQTMLLRDAFVLDFATDNTNVILSYGPCQFPTLGFIVERFWEVQSHEPE 1624
            IDLRIGASFTRFQTMLLRDAFVLDFA D+ N++LSYGPCQFPTLGF+VER+WE+QSHEPE
Sbjct: 178  IDLRIGASFTRFQTMLLRDAFVLDFAADDRNLVLSYGPCQFPTLGFVVERYWEIQSHEPE 237

Query: 1623 EFWTINCTHNSEEGTATFNWMRGHLFDYTCAMIIYEMCVQEPTATVTNVRQQEKLKYPPH 1444
            EFWTINC+H S+EGT+TFNWMR HLFDYTCA+IIYEMC+QEPTATVT VRQQEKLKYPPH
Sbjct: 238  EFWTINCSHKSDEGTSTFNWMRAHLFDYTCAVIIYEMCIQEPTATVTKVRQQEKLKYPPH 297

Query: 1443 PLSTIELEKRASRYFRMSSEHTMKVAEDLYQAGFISYPRTETDCFSVRTDLHTIVQEQQG 1264
            PL+TIELEKRASRYF MSSEHTMKVAEDLYQ GFISYPRTETD FS RTDLH IVQEQ G
Sbjct: 298  PLNTIELEKRASRYFHMSSEHTMKVAEDLYQTGFISYPRTETDYFSERTDLHGIVQEQLG 357

Query: 1263 HPVWGSYAQRLLDPEASLWRNPSGGGHDDKAHPPIHPTKFSAGESGWSPDHHKVYELVVR 1084
            HP+WGSYAQRLLDP A LWRNPS GGHDDKAHPPIHPTKFSAGESGWS DH ++YELVVR
Sbjct: 358  HPIWGSYAQRLLDPGAGLWRNPSNGGHDDKAHPPIHPTKFSAGESGWSQDHQRLYELVVR 417

Query: 1083 HFLACVSQPAIGAETTVEIDIACEQFSASGRVIIAKNYLDVYRFETWGGSMIPTYNYGQQ 904
            HFLACVSQPA+GAET VEIDIA E FS+SGRVIIAKNYLDVYRFE+WGGSMIPTY +GQQ
Sbjct: 418  HFLACVSQPAVGAETIVEIDIAGESFSSSGRVIIAKNYLDVYRFESWGGSMIPTYVFGQQ 477

Query: 903  FTPTTLTLDAGVTRPPPLLSEADLLSCMDKAGIGTDATMHDHIKKLLDRFYATKDSSMRF 724
            F PTTLTLD+GVTRPPPLLSEADLL+CMDKAGIGTDATMHDHIKKLLDRFYATKDS+ RF
Sbjct: 478  FIPTTLTLDSGVTRPPPLLSEADLLNCMDKAGIGTDATMHDHIKKLLDRFYATKDSNTRF 537

Query: 723  SPTKLGEALVMGYDDMGYELWKPYLRAMMESDMKAVSMGTKRKAEVLEACLQQMKACFVD 544
            SPT LGEALVMGYDDMGYELWKPYLR+MME DMKAVS+GTKR+ EVL  CL+QMKACF+D
Sbjct: 538  SPTNLGEALVMGYDDMGYELWKPYLRSMMECDMKAVSIGTKRRNEVLTTCLEQMKACFLD 597

Query: 543  ARLNKGKLFEAMAVFFERSNRSNSNEQHAIGEVVRKCGLCQESDMVLRKKPDGNFMVGCL 364
            ARLNK KL EAMA+FFE   RS+ +EQH +G+VVR+C LCQESDMVLR+KPDGNFMVGCL
Sbjct: 598  ARLNKVKLLEAMALFFE---RSSGDEQHEVGDVVRQCTLCQESDMVLRRKPDGNFMVGCL 654

Query: 363  GFPQCRNVVWLPGSVSEAIVTTNICSTCSPGPVYLIQFKFRRLEIPPNYNVNHLGCIGGC 184
            G+PQCRNVVWLPGS+SEA +TT  C+ C+PGPVY IQFKFRRLEIPPNYN++HLGC+ GC
Sbjct: 655  GYPQCRNVVWLPGSISEAAITTISCNHCTPGPVYKIQFKFRRLEIPPNYNIDHLGCVCGC 714

Query: 183  DDILRQLVEVCGTGSRNNSSVP 118
            D+ILRQL E+CGTGSR  S+VP
Sbjct: 715  DEILRQLTEICGTGSRICSTVP 736


>ref|XP_010674423.1| PREDICTED: DNA topoisomerase 3-alpha isoform X2 [Beta vulgaris subsp.
            vulgaris] gi|870862863|gb|KMT14051.1| hypothetical
            protein BVRB_4g078790 [Beta vulgaris subsp. vulgaris]
          Length = 918

 Score = 1289 bits (3335), Expect = 0.0
 Identities = 598/743 (80%), Positives = 680/743 (91%)
 Frame = -1

Query: 2355 GGRPLRALNVAEKPSVAKAVSGILSKTPSSGGLRVRDGRSRYNRIFEFNYTIQNQQVHMS 2176
            G RP+RALNVAEKPSVAKAVSGILS   +    RVR+GRSRYN+IFEF+YTI+ Q +HM 
Sbjct: 3    GNRPIRALNVAEKPSVAKAVSGILSGNQA----RVREGRSRYNKIFEFDYTIRGQPIHML 58

Query: 2175 FTSVTGHLMELDFEDRYRKWHSCDPVDLYHAPVKKYVPEDKSEIEKTLEEEARKCQWLIL 1996
            FTSVTGHLMEL+F+DRYRKWHSCDPV+LY APV+K VP+DKS+I++TL++E R CQWLIL
Sbjct: 59   FTSVTGHLMELEFDDRYRKWHSCDPVELYQAPVRKGVPQDKSDIKRTLQQEIRSCQWLIL 118

Query: 1995 WLDCDREGENIAFEVVEVCTRANRNLNIWRARFSALIDREIHYSVQHLVRPNQLFSDAVD 1816
            WLDCDREGENIAFEV+EVC   N NLN+WRARFSALIDREIH +VQ+L RPNQ F+DAVD
Sbjct: 119  WLDCDREGENIAFEVIEVCAEVNPNLNMWRARFSALIDREIHEAVQNLDRPNQSFADAVD 178

Query: 1815 ARQEIDLRIGASFTRFQTMLLRDAFVLDFATDNTNVILSYGPCQFPTLGFIVERFWEVQS 1636
            ARQEIDLRIGASFTRFQTMLL+DAF  +FATD+ +++LSYGPCQFPTLGF+VER+WE+Q+
Sbjct: 179  ARQEIDLRIGASFTRFQTMLLKDAFNFNFATDDRSLVLSYGPCQFPTLGFVVERYWEIQA 238

Query: 1635 HEPEEFWTINCTHNSEEGTATFNWMRGHLFDYTCAMIIYEMCVQEPTATVTNVRQQEKLK 1456
            HEPEEFWTINC+HNSEEGTA F+WMRGH+FDYTCA+ IYEMCV+EP ATVT VRQQEKLK
Sbjct: 239  HEPEEFWTINCSHNSEEGTANFSWMRGHIFDYTCAVSIYEMCVEEPIATVTMVRQQEKLK 298

Query: 1455 YPPHPLSTIELEKRASRYFRMSSEHTMKVAEDLYQAGFISYPRTETDCFSVRTDLHTIVQ 1276
            YPP+PLSTIELEKRASRYFRMSSE TMKVAE+LYQ+GFISYPRTETD FS RTDLHTIVQ
Sbjct: 299  YPPYPLSTIELEKRASRYFRMSSEQTMKVAEELYQSGFISYPRTETDSFSARTDLHTIVQ 358

Query: 1275 EQQGHPVWGSYAQRLLDPEASLWRNPSGGGHDDKAHPPIHPTKFSAGESGWSPDHHKVYE 1096
            EQQ HPVWGSYAQRLLDPEA+LW+NP  GGHDDKAHPPIHPTKFSAGES WS DHHKVYE
Sbjct: 359  EQQAHPVWGSYAQRLLDPEAALWKNPGSGGHDDKAHPPIHPTKFSAGESRWSQDHHKVYE 418

Query: 1095 LVVRHFLACVSQPAIGAETTVEIDIACEQFSASGRVIIAKNYLDVYRFETWGGSMIPTYN 916
            LVVRHFLACVSQPA+ AETTVEIDIA E FSASGRVI++KNYLD+YR+E+WGGS+IPTY 
Sbjct: 419  LVVRHFLACVSQPAVSAETTVEIDIAGELFSASGRVILSKNYLDIYRYESWGGSVIPTYM 478

Query: 915  YGQQFTPTTLTLDAGVTRPPPLLSEADLLSCMDKAGIGTDATMHDHIKKLLDRFYATKDS 736
            +GQQFTPTTLTLD+GVTRPPPLLSEADLL CMDKAGIGTDATMHDHIKKLLDRFYA KD+
Sbjct: 479  FGQQFTPTTLTLDSGVTRPPPLLSEADLLGCMDKAGIGTDATMHDHIKKLLDRFYAVKDA 538

Query: 735  SMRFSPTKLGEALVMGYDDMGYELWKPYLRAMMESDMKAVSMGTKRKAEVLEACLQQMKA 556
            + RFSPT LGEALVMGYDDMGYELWKPYLR+ ME DMKAVS+G KRK E+L +CLQ+MKA
Sbjct: 539  NTRFSPTNLGEALVMGYDDMGYELWKPYLRSKMEDDMKAVSLGIKRKIEILASCLQEMKA 598

Query: 555  CFVDARLNKGKLFEAMAVFFERSNRSNSNEQHAIGEVVRKCGLCQESDMVLRKKPDGNFM 376
            CF+DA+ NK KLFEAM +FF+R+NR    EQHAIGEVVR+CGLC+++DMVL++KPDG FM
Sbjct: 599  CFLDAKQNKVKLFEAMEIFFDRTNRPGVEEQHAIGEVVRRCGLCRQADMVLKRKPDGKFM 658

Query: 375  VGCLGFPQCRNVVWLPGSVSEAIVTTNICSTCSPGPVYLIQFKFRRLEIPPNYNVNHLGC 196
            VGCLGFPQCRNVVWLPGS+SEA+VT+N C++CSPGP+++IQFKFRRLEIPPNY+V+HLGC
Sbjct: 659  VGCLGFPQCRNVVWLPGSISEAVVTSNTCNSCSPGPIFMIQFKFRRLEIPPNYSVDHLGC 718

Query: 195  IGGCDDILRQLVEVCGTGSRNNS 127
            +GGCDD L+QL E+CGTG RN S
Sbjct: 719  VGGCDDTLKQLTEICGTGPRNLS 741


>ref|XP_010674422.1| PREDICTED: DNA topoisomerase 3-alpha isoform X1 [Beta vulgaris subsp.
            vulgaris]
          Length = 930

 Score = 1289 bits (3335), Expect = 0.0
 Identities = 598/743 (80%), Positives = 680/743 (91%)
 Frame = -1

Query: 2355 GGRPLRALNVAEKPSVAKAVSGILSKTPSSGGLRVRDGRSRYNRIFEFNYTIQNQQVHMS 2176
            G RP+RALNVAEKPSVAKAVSGILS   +    RVR+GRSRYN+IFEF+YTI+ Q +HM 
Sbjct: 3    GNRPIRALNVAEKPSVAKAVSGILSGNQA----RVREGRSRYNKIFEFDYTIRGQPIHML 58

Query: 2175 FTSVTGHLMELDFEDRYRKWHSCDPVDLYHAPVKKYVPEDKSEIEKTLEEEARKCQWLIL 1996
            FTSVTGHLMEL+F+DRYRKWHSCDPV+LY APV+K VP+DKS+I++TL++E R CQWLIL
Sbjct: 59   FTSVTGHLMELEFDDRYRKWHSCDPVELYQAPVRKGVPQDKSDIKRTLQQEIRSCQWLIL 118

Query: 1995 WLDCDREGENIAFEVVEVCTRANRNLNIWRARFSALIDREIHYSVQHLVRPNQLFSDAVD 1816
            WLDCDREGENIAFEV+EVC   N NLN+WRARFSALIDREIH +VQ+L RPNQ F+DAVD
Sbjct: 119  WLDCDREGENIAFEVIEVCAEVNPNLNMWRARFSALIDREIHEAVQNLDRPNQSFADAVD 178

Query: 1815 ARQEIDLRIGASFTRFQTMLLRDAFVLDFATDNTNVILSYGPCQFPTLGFIVERFWEVQS 1636
            ARQEIDLRIGASFTRFQTMLL+DAF  +FATD+ +++LSYGPCQFPTLGF+VER+WE+Q+
Sbjct: 179  ARQEIDLRIGASFTRFQTMLLKDAFNFNFATDDRSLVLSYGPCQFPTLGFVVERYWEIQA 238

Query: 1635 HEPEEFWTINCTHNSEEGTATFNWMRGHLFDYTCAMIIYEMCVQEPTATVTNVRQQEKLK 1456
            HEPEEFWTINC+HNSEEGTA F+WMRGH+FDYTCA+ IYEMCV+EP ATVT VRQQEKLK
Sbjct: 239  HEPEEFWTINCSHNSEEGTANFSWMRGHIFDYTCAVSIYEMCVEEPIATVTMVRQQEKLK 298

Query: 1455 YPPHPLSTIELEKRASRYFRMSSEHTMKVAEDLYQAGFISYPRTETDCFSVRTDLHTIVQ 1276
            YPP+PLSTIELEKRASRYFRMSSE TMKVAE+LYQ+GFISYPRTETD FS RTDLHTIVQ
Sbjct: 299  YPPYPLSTIELEKRASRYFRMSSEQTMKVAEELYQSGFISYPRTETDSFSARTDLHTIVQ 358

Query: 1275 EQQGHPVWGSYAQRLLDPEASLWRNPSGGGHDDKAHPPIHPTKFSAGESGWSPDHHKVYE 1096
            EQQ HPVWGSYAQRLLDPEA+LW+NP  GGHDDKAHPPIHPTKFSAGES WS DHHKVYE
Sbjct: 359  EQQAHPVWGSYAQRLLDPEAALWKNPGSGGHDDKAHPPIHPTKFSAGESRWSQDHHKVYE 418

Query: 1095 LVVRHFLACVSQPAIGAETTVEIDIACEQFSASGRVIIAKNYLDVYRFETWGGSMIPTYN 916
            LVVRHFLACVSQPA+ AETTVEIDIA E FSASGRVI++KNYLD+YR+E+WGGS+IPTY 
Sbjct: 419  LVVRHFLACVSQPAVSAETTVEIDIAGELFSASGRVILSKNYLDIYRYESWGGSVIPTYM 478

Query: 915  YGQQFTPTTLTLDAGVTRPPPLLSEADLLSCMDKAGIGTDATMHDHIKKLLDRFYATKDS 736
            +GQQFTPTTLTLD+GVTRPPPLLSEADLL CMDKAGIGTDATMHDHIKKLLDRFYA KD+
Sbjct: 479  FGQQFTPTTLTLDSGVTRPPPLLSEADLLGCMDKAGIGTDATMHDHIKKLLDRFYAVKDA 538

Query: 735  SMRFSPTKLGEALVMGYDDMGYELWKPYLRAMMESDMKAVSMGTKRKAEVLEACLQQMKA 556
            + RFSPT LGEALVMGYDDMGYELWKPYLR+ ME DMKAVS+G KRK E+L +CLQ+MKA
Sbjct: 539  NTRFSPTNLGEALVMGYDDMGYELWKPYLRSKMEDDMKAVSLGIKRKIEILASCLQEMKA 598

Query: 555  CFVDARLNKGKLFEAMAVFFERSNRSNSNEQHAIGEVVRKCGLCQESDMVLRKKPDGNFM 376
            CF+DA+ NK KLFEAM +FF+R+NR    EQHAIGEVVR+CGLC+++DMVL++KPDG FM
Sbjct: 599  CFLDAKQNKVKLFEAMEIFFDRTNRPGVEEQHAIGEVVRRCGLCRQADMVLKRKPDGKFM 658

Query: 375  VGCLGFPQCRNVVWLPGSVSEAIVTTNICSTCSPGPVYLIQFKFRRLEIPPNYNVNHLGC 196
            VGCLGFPQCRNVVWLPGS+SEA+VT+N C++CSPGP+++IQFKFRRLEIPPNY+V+HLGC
Sbjct: 659  VGCLGFPQCRNVVWLPGSISEAVVTSNTCNSCSPGPIFMIQFKFRRLEIPPNYSVDHLGC 718

Query: 195  IGGCDDILRQLVEVCGTGSRNNS 127
            +GGCDD L+QL E+CGTG RN S
Sbjct: 719  VGGCDDTLKQLTEICGTGPRNLS 741


>emb|CDP04613.1| unnamed protein product [Coffea canephora]
          Length = 925

 Score = 1289 bits (3335), Expect = 0.0
 Identities = 605/749 (80%), Positives = 673/749 (89%)
 Frame = -1

Query: 2361 GGGGRPLRALNVAEKPSVAKAVSGILSKTPSSGGLRVRDGRSRYNRIFEFNYTIQNQQVH 2182
            G GGR +R LNVAEKPSVAKAVSG LSK    GGLRVRDGRSRYN+IFEFN+T+  Q  H
Sbjct: 11   GSGGRAIRVLNVAEKPSVAKAVSGFLSKN-QQGGLRVRDGRSRYNKIFEFNHTVNGQPCH 69

Query: 2181 MSFTSVTGHLMELDFEDRYRKWHSCDPVDLYHAPVKKYVPEDKSEIEKTLEEEARKCQWL 2002
            MSFTSVTGHLMELDF+DR+R+WHSCDPVDLYHA V+K+VPEDKS+I +TLEEEARKCQWL
Sbjct: 70   MSFTSVTGHLMELDFDDRFRRWHSCDPVDLYHASVRKFVPEDKSDIRRTLEEEARKCQWL 129

Query: 2001 ILWLDCDREGENIAFEVVEVCTRANRNLNIWRARFSALIDREIHYSVQHLVRPNQLFSDA 1822
            ILWLDCDREGENIAFEV+EVCT+ANRNLN+WRARFSALI+REI  SVQ+LVRPNQLF+DA
Sbjct: 130  ILWLDCDREGENIAFEVIEVCTQANRNLNVWRARFSALIEREIQNSVQNLVRPNQLFADA 189

Query: 1821 VDARQEIDLRIGASFTRFQTMLLRDAFVLDFATDNTNVILSYGPCQFPTLGFIVERFWEV 1642
            VD RQEIDLRIGASFTRFQTM LRDAF+++ ATD+ N+++SYGPCQFPTLGF+VER+WE 
Sbjct: 190  VDLRQEIDLRIGASFTRFQTMFLRDAFMINLATDDRNLVISYGPCQFPTLGFVVERYWEN 249

Query: 1641 QSHEPEEFWTINCTHNSEEGTATFNWMRGHLFDYTCAMIIYEMCVQEPTATVTNVRQQEK 1462
            QSHE EEFWTINCTHN++EGTA F WMRGH FDYTCA I+YEMC+QEPT TVT +++QEK
Sbjct: 250  QSHEAEEFWTINCTHNTDEGTANFKWMRGHFFDYTCAAIVYEMCIQEPTVTVTEIKEQEK 309

Query: 1461 LKYPPHPLSTIELEKRASRYFRMSSEHTMKVAEDLYQAGFISYPRTETDCFSVRTDLHTI 1282
            LKYPP PLST+ELEKRASR+F MS  HTMKVAEDLYQAGFISYPRTETD FS +TDL  I
Sbjct: 310  LKYPPLPLSTLELEKRASRFFHMSPAHTMKVAEDLYQAGFISYPRTETDGFSEKTDLRAI 369

Query: 1281 VQEQQGHPVWGSYAQRLLDPEASLWRNPSGGGHDDKAHPPIHPTKFSAGESGWSPDHHKV 1102
            V EQQGHP+WGSYAQ LL+PEA LWRNPS G HDDKAHPPIHPT+FS GESGWS DHH++
Sbjct: 370  VFEQQGHPLWGSYAQLLLNPEAGLWRNPSSGRHDDKAHPPIHPTRFSPGESGWSRDHHRL 429

Query: 1101 YELVVRHFLACVSQPAIGAETTVEIDIACEQFSASGRVIIAKNYLDVYRFETWGGSMIPT 922
            YELVVRHFLACVSQPA  AET+VEIDIA E FS+SGRVI AKNYLDVY FE+WGGSMIPT
Sbjct: 430  YELVVRHFLACVSQPAKAAETSVEIDIAGEAFSSSGRVIHAKNYLDVYTFESWGGSMIPT 489

Query: 921  YNYGQQFTPTTLTLDAGVTRPPPLLSEADLLSCMDKAGIGTDATMHDHIKKLLDRFYATK 742
            Y  GQQF PTTLTLD+GVTRPPPLLSEADLL+CMDKAGIGTDATMH+HI+KLLDR YA K
Sbjct: 490  YTLGQQFMPTTLTLDSGVTRPPPLLSEADLLTCMDKAGIGTDATMHEHIQKLLDRHYAIK 549

Query: 741  DSSMRFSPTKLGEALVMGYDDMGYELWKPYLRAMMESDMKAVSMGTKRKAEVLEACLQQM 562
               +RFSPT LGEALVMGYDDMGYELWKPYLRAMMESDMKAVS+GTKRK EVLE CLQQM
Sbjct: 550  TPDIRFSPTNLGEALVMGYDDMGYELWKPYLRAMMESDMKAVSIGTKRKTEVLETCLQQM 609

Query: 561  KACFVDARLNKGKLFEAMAVFFERSNRSNSNEQHAIGEVVRKCGLCQESDMVLRKKPDGN 382
            KACF+DAR NKGKLFEAMA+FFERSNRSN N+ +  G+VVRKC +C ESD+VL++KPDG+
Sbjct: 610  KACFIDARANKGKLFEAMAIFFERSNRSNDNQHNTGGDVVRKCSICHESDLVLKQKPDGH 669

Query: 381  FMVGCLGFPQCRNVVWLPGSVSEAIVTTNICSTCSPGPVYLIQFKFRRLEIPPNYNVNHL 202
            FMVGCLGFPQCRNVVWLPGS+S+A VT +IC  C+PGPV+ IQFKFRRLEIPPNYNV+HL
Sbjct: 670  FMVGCLGFPQCRNVVWLPGSISQAAVTHDICGICTPGPVFKIQFKFRRLEIPPNYNVDHL 729

Query: 201  GCIGGCDDILRQLVEVCGTGSRNNSSVPG 115
            GCIGGCDD LRQLVE+CGTG+R  SSV G
Sbjct: 730  GCIGGCDDTLRQLVEICGTGARTASSVSG 758


>gb|KNA10476.1| hypothetical protein SOVF_143990 [Spinacia oleracea]
          Length = 941

 Score = 1286 bits (3327), Expect = 0.0
 Identities = 600/741 (80%), Positives = 674/741 (90%)
 Frame = -1

Query: 2355 GGRPLRALNVAEKPSVAKAVSGILSKTPSSGGLRVRDGRSRYNRIFEFNYTIQNQQVHMS 2176
            G R +RALNVAEKPSVAKAVSGILS+  +    RVR+GRSRYN+IFEF+YTI+ Q +HM 
Sbjct: 3    GNRQIRALNVAEKPSVAKAVSGILSRNQA----RVREGRSRYNKIFEFDYTIRGQPIHML 58

Query: 2175 FTSVTGHLMELDFEDRYRKWHSCDPVDLYHAPVKKYVPEDKSEIEKTLEEEARKCQWLIL 1996
            FTSVTGHLMEL+F+DRYRKWHSCDP +LY APV+K VP+DK +I++TL++EAR CQWLIL
Sbjct: 59   FTSVTGHLMELEFDDRYRKWHSCDPSELYQAPVRKTVPQDKLDIKRTLQQEARSCQWLIL 118

Query: 1995 WLDCDREGENIAFEVVEVCTRANRNLNIWRARFSALIDREIHYSVQHLVRPNQLFSDAVD 1816
            WLDCDREGENIA+EV+EVCT ANRN+N WRARFSALIDR+IH +VQ+L RPNQ FS+AVD
Sbjct: 119  WLDCDREGENIAYEVIEVCTEANRNMNTWRARFSALIDRDIHEAVQNLDRPNQSFSEAVD 178

Query: 1815 ARQEIDLRIGASFTRFQTMLLRDAFVLDFATDNTNVILSYGPCQFPTLGFIVERFWEVQS 1636
            ARQEIDLRIGASFTRFQTMLL+DAF  DFAT++ N+ILSYGPCQFPTLGFIVER+WE+Q+
Sbjct: 179  ARQEIDLRIGASFTRFQTMLLKDAFHFDFATEDRNLILSYGPCQFPTLGFIVERYWEIQA 238

Query: 1635 HEPEEFWTINCTHNSEEGTATFNWMRGHLFDYTCAMIIYEMCVQEPTATVTNVRQQEKLK 1456
            HEPEEFWTINC+HNSEEGTA F+WMRGH+FDYTCA+ IYEMCV+EPTATVT VRQQEKLK
Sbjct: 239  HEPEEFWTINCSHNSEEGTANFSWMRGHMFDYTCAVTIYEMCVEEPTATVTMVRQQEKLK 298

Query: 1455 YPPHPLSTIELEKRASRYFRMSSEHTMKVAEDLYQAGFISYPRTETDCFSVRTDLHTIVQ 1276
            YPP+PLSTIELEKRASRYFR+SSEHTMKVAE+LYQ+GFISYPRTETD FS RTDL  I Q
Sbjct: 299  YPPYPLSTIELEKRASRYFRLSSEHTMKVAEELYQSGFISYPRTETDSFSARTDLRAIAQ 358

Query: 1275 EQQGHPVWGSYAQRLLDPEASLWRNPSGGGHDDKAHPPIHPTKFSAGESGWSPDHHKVYE 1096
            EQQ HPVWG YAQRL+DPEA LWRNP  GGHDDKAHPPIHPTKFSAGESGWS DHHKVYE
Sbjct: 359  EQQAHPVWGPYAQRLMDPEADLWRNPGNGGHDDKAHPPIHPTKFSAGESGWSQDHHKVYE 418

Query: 1095 LVVRHFLACVSQPAIGAETTVEIDIACEQFSASGRVIIAKNYLDVYRFETWGGSMIPTYN 916
            LVVRHFLACVSQPA+ AETTVEIDIA E FSA GRVI+AKNYLDVYRF+TWGGS IPTY 
Sbjct: 419  LVVRHFLACVSQPAVSAETTVEIDIAGELFSACGRVILAKNYLDVYRFDTWGGSFIPTYM 478

Query: 915  YGQQFTPTTLTLDAGVTRPPPLLSEADLLSCMDKAGIGTDATMHDHIKKLLDRFYATKDS 736
             GQQF PTTLTLD+GVTRPPPLLSEADLLSCMDKAGIGTDATMHDHIKKLLDRFYATKD+
Sbjct: 479  LGQQFAPTTLTLDSGVTRPPPLLSEADLLSCMDKAGIGTDATMHDHIKKLLDRFYATKDA 538

Query: 735  SMRFSPTKLGEALVMGYDDMGYELWKPYLRAMMESDMKAVSMGTKRKAEVLEACLQQMKA 556
            + RFSPT LGE+LVMGYDDMGYELWKPYLR+ ME DMKAVS+GTKRKA++L +CLQ+MKA
Sbjct: 539  NTRFSPTNLGESLVMGYDDMGYELWKPYLRSKMEDDMKAVSLGTKRKADILASCLQEMKA 598

Query: 555  CFVDARLNKGKLFEAMAVFFERSNRSNSNEQHAIGEVVRKCGLCQESDMVLRKKPDGNFM 376
            CF+DARLNK KLFEAM +FF+R+NR+ + EQ  IG VVR+CGLCQ++DMVLR++ DG FM
Sbjct: 599  CFLDARLNKVKLFEAMGIFFDRTNRTGAEEQQTIGGVVRRCGLCQQADMVLRRRQDGKFM 658

Query: 375  VGCLGFPQCRNVVWLPGSVSEAIVTTNICSTCSPGPVYLIQFKFRRLEIPPNYNVNHLGC 196
            VGCLG+PQCR VVWLPGS+SEA VT+N C+ CSPGPV+LIQFKFRRLEIPPNY+V+HLGC
Sbjct: 659  VGCLGYPQCRKVVWLPGSISEAAVTSNTCNVCSPGPVFLIQFKFRRLEIPPNYSVDHLGC 718

Query: 195  IGGCDDILRQLVEVCGTGSRN 133
            IGGCDD LRQL E+CGTG RN
Sbjct: 719  IGGCDDTLRQLTEICGTGPRN 739


>ref|XP_004502963.1| PREDICTED: DNA topoisomerase 3-alpha [Cicer arietinum]
          Length = 920

 Score = 1278 bits (3308), Expect = 0.0
 Identities = 604/739 (81%), Positives = 667/739 (90%)
 Frame = -1

Query: 2352 GRPLRALNVAEKPSVAKAVSGILSKTPSSGGLRVRDGRSRYNRIFEFNYTIQNQQVHMSF 2173
            GR +  LNVAEKPSVAK+V+ ILS+     GLRVRDGRSRYNRIFEFNYTI+ Q  HM F
Sbjct: 3    GRGVTVLNVAEKPSVAKSVANILSRNQ---GLRVRDGRSRYNRIFEFNYTIRGQPCHMLF 59

Query: 2172 TSVTGHLMELDFEDRYRKWHSCDPVDLYHAPVKKYVPEDKSEIEKTLEEEARKCQWLILW 1993
            TSV GHLMEL+FEDRYRKWHSCDP DLYHAPV+K VPEDK +I++TLEEEAR+CQWL+LW
Sbjct: 60   TSVIGHLMELEFEDRYRKWHSCDPADLYHAPVRKSVPEDKKDIKRTLEEEARRCQWLVLW 119

Query: 1992 LDCDREGENIAFEVVEVCTRANRNLNIWRARFSALIDREIHYSVQHLVRPNQLFSDAVDA 1813
            LDCDREGENIAFEVV+VCT AN +L I RARFSALIDREIH +VQ+LV PN+ F+DAVDA
Sbjct: 120  LDCDREGENIAFEVVDVCTAANPHLTIKRARFSALIDREIHQAVQNLVEPNKWFADAVDA 179

Query: 1812 RQEIDLRIGASFTRFQTMLLRDAFVLDFATDNTNVILSYGPCQFPTLGFIVERFWEVQSH 1633
            RQEIDLRIGASFTRFQTML++DAF++D  TD+ N+ILSYGPCQFPTLGF+VER+WE+Q+H
Sbjct: 180  RQEIDLRIGASFTRFQTMLMKDAFIIDTITDDRNIILSYGPCQFPTLGFVVERYWEIQAH 239

Query: 1632 EPEEFWTINCTHNSEEGTATFNWMRGHLFDYTCAMIIYEMCVQEPTATVTNVRQQEKLKY 1453
            EPEEFW+INC+H S+EG A F+W RGHLFDYTCA+IIYEMC +EPTATVTNVRQQEKLKY
Sbjct: 240  EPEEFWSINCSHRSDEGVANFSWGRGHLFDYTCAVIIYEMCTEEPTATVTNVRQQEKLKY 299

Query: 1452 PPHPLSTIELEKRASRYFRMSSEHTMKVAEDLYQAGFISYPRTETDCFSVRTDLHTIVQE 1273
            PPHPLSTIELEKRASRYFRMSSEHTMKVAE+LYQ+GFISYPRTETD FS RTDLH IVQE
Sbjct: 300  PPHPLSTIELEKRASRYFRMSSEHTMKVAEELYQSGFISYPRTETDNFSSRTDLHAIVQE 359

Query: 1272 QQGHPVWGSYAQRLLDPEASLWRNPSGGGHDDKAHPPIHPTKFSAGESGWSPDHHKVYEL 1093
            QQGHP WG YAQRLLDPEA LWRNP GGGHDDKAHPPIHPTKFSAGESGWS DH K+YEL
Sbjct: 360  QQGHPQWGVYAQRLLDPEAGLWRNPRGGGHDDKAHPPIHPTKFSAGESGWSQDHRKLYEL 419

Query: 1092 VVRHFLACVSQPAIGAETTVEIDIACEQFSASGRVIIAKNYLDVYRFETWGGSMIPTYNY 913
            VVRHFLACVS+PA+GAETTVEIDIA E FSA GRVI+ KNYLDVY++E+WGGS+IPTY  
Sbjct: 420  VVRHFLACVSKPAVGAETTVEIDIAGELFSACGRVILEKNYLDVYQYESWGGSIIPTYTI 479

Query: 912  GQQFTPTTLTLDAGVTRPPPLLSEADLLSCMDKAGIGTDATMHDHIKKLLDRFYATKDSS 733
            GQQF PTTLTLD+GVTRPPP LSEADLLSCMDK GIGTDATMHDHIKKLLDRFYATKD+S
Sbjct: 480  GQQFIPTTLTLDSGVTRPPPPLSEADLLSCMDKEGIGTDATMHDHIKKLLDRFYATKDAS 539

Query: 732  MRFSPTKLGEALVMGYDDMGYELWKPYLRAMMESDMKAVSMGTKRKAEVLEACLQQMKAC 553
            MRF+PT LGEALVMGYDDMGY+LWKPYLRA+ME DMK+VS GTK K EVL+  LQQMKAC
Sbjct: 540  MRFTPTNLGEALVMGYDDMGYKLWKPYLRAVMERDMKSVSEGTKSKTEVLDTSLQQMKAC 599

Query: 552  FVDARLNKGKLFEAMAVFFERSNRSNSNEQHAIGEVVRKCGLCQESDMVLRKKPDGNFMV 373
            F+DARLNK KL EAM +FFERSNRS   EQ+AIGEVVR+CGLC+ESDMVL+K  DGNFMV
Sbjct: 600  FLDARLNKVKLLEAMGIFFERSNRSGGEEQNAIGEVVRRCGLCRESDMVLKKSRDGNFMV 659

Query: 372  GCLGFPQCRNVVWLPGSVSEAIVTTNICSTCSPGPVYLIQFKFRRLEIPPNYNVNHLGCI 193
            GCLGFPQCRN VWLPGSVSEA+VTTN CS C+PGPVY IQFKFR+LEIPPNY+VNHLGCI
Sbjct: 660  GCLGFPQCRNAVWLPGSVSEAVVTTNTCSNCTPGPVYRIQFKFRQLEIPPNYDVNHLGCI 719

Query: 192  GGCDDILRQLVEVCGTGSR 136
            GGCD+IL QL E+CGTG R
Sbjct: 720  GGCDEILTQLTEICGTGPR 738


>ref|XP_007048481.1| Topoisomerase 3alpha isoform 2, partial [Theobroma cacao]
            gi|508700742|gb|EOX92638.1| Topoisomerase 3alpha isoform
            2, partial [Theobroma cacao]
          Length = 845

 Score = 1276 bits (3302), Expect = 0.0
 Identities = 601/736 (81%), Positives = 663/736 (90%)
 Frame = -1

Query: 2343 LRALNVAEKPSVAKAVSGILSKTPSSGGLRVRDGRSRYNRIFEFNYTIQNQQVHMSFTSV 2164
            ++ LNVAEKPSVAK+VSGILS+     GLRVRDGRSR+NRIFEFNY+++ Q  HM FTSV
Sbjct: 5    IKVLNVAEKPSVAKSVSGILSRNQ---GLRVRDGRSRFNRIFEFNYSVRGQPCHMLFTSV 61

Query: 2163 TGHLMELDFEDRYRKWHSCDPVDLYHAPVKKYVPEDKSEIEKTLEEEARKCQWLILWLDC 1984
            TGHLMEL+FEDR+RKWHSCDP DLYHAPV+K+VPEDK +I++TLEEEAR+CQWL+LWLDC
Sbjct: 62   TGHLMELEFEDRFRKWHSCDPADLYHAPVRKHVPEDKMDIKRTLEEEARRCQWLVLWLDC 121

Query: 1983 DREGENIAFEVVEVCTRANRNLNIWRARFSALIDREIHYSVQHLVRPNQLFSDAVDARQE 1804
            DREGENIAFEV++VC   N +L I RARFSALI+REIH++ Q+LV PN  FSDAVDARQE
Sbjct: 122  DREGENIAFEVIDVCRAVNCHLTIRRARFSALIEREIHHATQNLVDPNPWFSDAVDARQE 181

Query: 1803 IDLRIGASFTRFQTMLLRDAFVLDFATDNTNVILSYGPCQFPTLGFIVERFWEVQSHEPE 1624
            IDLRIGASFTRFQTM+LRD FV+D ATD+ N++LSYGPCQFPTLGF+VER+WEVQSHEPE
Sbjct: 182  IDLRIGASFTRFQTMMLRDKFVIDSATDDRNLVLSYGPCQFPTLGFVVERYWEVQSHEPE 241

Query: 1623 EFWTINCTHNSEEGTATFNWMRGHLFDYTCAMIIYEMCVQEPTATVTNVRQQEKLKYPPH 1444
            EFWTINC+H  +EG ATFNWMRGHLFD+TCA+I+YEMCVQEP ATVT VR QEKLKYPP+
Sbjct: 242  EFWTINCSHKLDEGVATFNWMRGHLFDHTCAVIVYEMCVQEPNATVTKVRHQEKLKYPPY 301

Query: 1443 PLSTIELEKRASRYFRMSSEHTMKVAEDLYQAGFISYPRTETDCFSVRTDLHTIVQEQQG 1264
            PLSTIELEKRASRYFRMSSEHTMKVAEDLYQAGFISYPRTETDCFS RTDLH IVQEQQ 
Sbjct: 302  PLSTIELEKRASRYFRMSSEHTMKVAEDLYQAGFISYPRTETDCFSSRTDLHAIVQEQQD 361

Query: 1263 HPVWGSYAQRLLDPEASLWRNPSGGGHDDKAHPPIHPTKFSAGESGWSPDHHKVYELVVR 1084
            HP WGSYAQRLLDP  SLWRNPS GGHDDKAHPPIHPTKFSAGE  WS DH K+YELVVR
Sbjct: 362  HPEWGSYAQRLLDPGTSLWRNPSSGGHDDKAHPPIHPTKFSAGEHNWSQDHRKLYELVVR 421

Query: 1083 HFLACVSQPAIGAETTVEIDIACEQFSASGRVIIAKNYLDVYRFETWGGSMIPTYNYGQQ 904
            HFLACVSQPA+GAETTVEIDIA EQFS SGRVI+ +NYLDVYR+E+WGGSMIPTY  GQQ
Sbjct: 422  HFLACVSQPAVGAETTVEIDIADEQFSTSGRVILERNYLDVYRYESWGGSMIPTYTLGQQ 481

Query: 903  FTPTTLTLDAGVTRPPPLLSEADLLSCMDKAGIGTDATMHDHIKKLLDRFYATKDSSMRF 724
            F PT+LTLD GVTRPPPLLSEADLLSCMDKAGIGTDATMHDHIKKLLDRFYATKDS+ RF
Sbjct: 482  FIPTSLTLDTGVTRPPPLLSEADLLSCMDKAGIGTDATMHDHIKKLLDRFYATKDSNTRF 541

Query: 723  SPTKLGEALVMGYDDMGYELWKPYLRAMMESDMKAVSMGTKRKAEVLEACLQQMKACFVD 544
            SPTKLGEALVMGYDDMGYELWKP LR+MME DMK VS+G KRK EVL  CLQQMKACF+D
Sbjct: 542  SPTKLGEALVMGYDDMGYELWKPNLRSMMEFDMKEVSVGNKRKDEVLATCLQQMKACFLD 601

Query: 543  ARLNKGKLFEAMAVFFERSNRSNSNEQHAIGEVVRKCGLCQESDMVLRKKPDGNFMVGCL 364
            ARLNK KL EAMAVFFERSN+S  ++ H  GEVVR+CGLC+ES MVL+K  DGNFMVGCL
Sbjct: 602  ARLNKVKLLEAMAVFFERSNQSAGDDNHVAGEVVRQCGLCRESSMVLKKNRDGNFMVGCL 661

Query: 363  GFPQCRNVVWLPGSVSEAIVTTNICSTCSPGPVYLIQFKFRRLEIPPNYNVNHLGCIGGC 184
            GFPQCRN +WLPGSV EA VT+NIC +C+PGPVYLIQFKFR+LEIPP +N NHLGCIGGC
Sbjct: 662  GFPQCRNAIWLPGSVLEAAVTSNICGSCNPGPVYLIQFKFRQLEIPPGFNANHLGCIGGC 721

Query: 183  DDILRQLVEVCGTGSR 136
            DDILRQL+E+CGTGSR
Sbjct: 722  DDILRQLIEICGTGSR 737


>ref|XP_007048480.1| Topoisomerase 3alpha isoform 1 [Theobroma cacao]
            gi|508700741|gb|EOX92637.1| Topoisomerase 3alpha isoform
            1 [Theobroma cacao]
          Length = 914

 Score = 1276 bits (3302), Expect = 0.0
 Identities = 601/736 (81%), Positives = 663/736 (90%)
 Frame = -1

Query: 2343 LRALNVAEKPSVAKAVSGILSKTPSSGGLRVRDGRSRYNRIFEFNYTIQNQQVHMSFTSV 2164
            ++ LNVAEKPSVAK+VSGILS+     GLRVRDGRSR+NRIFEFNY+++ Q  HM FTSV
Sbjct: 5    IKVLNVAEKPSVAKSVSGILSRNQ---GLRVRDGRSRFNRIFEFNYSVRGQPCHMLFTSV 61

Query: 2163 TGHLMELDFEDRYRKWHSCDPVDLYHAPVKKYVPEDKSEIEKTLEEEARKCQWLILWLDC 1984
            TGHLMEL+FEDR+RKWHSCDP DLYHAPV+K+VPEDK +I++TLEEEAR+CQWL+LWLDC
Sbjct: 62   TGHLMELEFEDRFRKWHSCDPADLYHAPVRKHVPEDKMDIKRTLEEEARRCQWLVLWLDC 121

Query: 1983 DREGENIAFEVVEVCTRANRNLNIWRARFSALIDREIHYSVQHLVRPNQLFSDAVDARQE 1804
            DREGENIAFEV++VC   N +L I RARFSALI+REIH++ Q+LV PN  FSDAVDARQE
Sbjct: 122  DREGENIAFEVIDVCRAVNCHLTIRRARFSALIEREIHHATQNLVDPNPWFSDAVDARQE 181

Query: 1803 IDLRIGASFTRFQTMLLRDAFVLDFATDNTNVILSYGPCQFPTLGFIVERFWEVQSHEPE 1624
            IDLRIGASFTRFQTM+LRD FV+D ATD+ N++LSYGPCQFPTLGF+VER+WEVQSHEPE
Sbjct: 182  IDLRIGASFTRFQTMMLRDKFVIDSATDDRNLVLSYGPCQFPTLGFVVERYWEVQSHEPE 241

Query: 1623 EFWTINCTHNSEEGTATFNWMRGHLFDYTCAMIIYEMCVQEPTATVTNVRQQEKLKYPPH 1444
            EFWTINC+H  +EG ATFNWMRGHLFD+TCA+I+YEMCVQEP ATVT VR QEKLKYPP+
Sbjct: 242  EFWTINCSHKLDEGVATFNWMRGHLFDHTCAVIVYEMCVQEPNATVTKVRHQEKLKYPPY 301

Query: 1443 PLSTIELEKRASRYFRMSSEHTMKVAEDLYQAGFISYPRTETDCFSVRTDLHTIVQEQQG 1264
            PLSTIELEKRASRYFRMSSEHTMKVAEDLYQAGFISYPRTETDCFS RTDLH IVQEQQ 
Sbjct: 302  PLSTIELEKRASRYFRMSSEHTMKVAEDLYQAGFISYPRTETDCFSSRTDLHAIVQEQQD 361

Query: 1263 HPVWGSYAQRLLDPEASLWRNPSGGGHDDKAHPPIHPTKFSAGESGWSPDHHKVYELVVR 1084
            HP WGSYAQRLLDP  SLWRNPS GGHDDKAHPPIHPTKFSAGE  WS DH K+YELVVR
Sbjct: 362  HPEWGSYAQRLLDPGTSLWRNPSSGGHDDKAHPPIHPTKFSAGEHNWSQDHRKLYELVVR 421

Query: 1083 HFLACVSQPAIGAETTVEIDIACEQFSASGRVIIAKNYLDVYRFETWGGSMIPTYNYGQQ 904
            HFLACVSQPA+GAETTVEIDIA EQFS SGRVI+ +NYLDVYR+E+WGGSMIPTY  GQQ
Sbjct: 422  HFLACVSQPAVGAETTVEIDIADEQFSTSGRVILERNYLDVYRYESWGGSMIPTYTLGQQ 481

Query: 903  FTPTTLTLDAGVTRPPPLLSEADLLSCMDKAGIGTDATMHDHIKKLLDRFYATKDSSMRF 724
            F PT+LTLD GVTRPPPLLSEADLLSCMDKAGIGTDATMHDHIKKLLDRFYATKDS+ RF
Sbjct: 482  FIPTSLTLDTGVTRPPPLLSEADLLSCMDKAGIGTDATMHDHIKKLLDRFYATKDSNTRF 541

Query: 723  SPTKLGEALVMGYDDMGYELWKPYLRAMMESDMKAVSMGTKRKAEVLEACLQQMKACFVD 544
            SPTKLGEALVMGYDDMGYELWKP LR+MME DMK VS+G KRK EVL  CLQQMKACF+D
Sbjct: 542  SPTKLGEALVMGYDDMGYELWKPNLRSMMEFDMKEVSVGNKRKDEVLATCLQQMKACFLD 601

Query: 543  ARLNKGKLFEAMAVFFERSNRSNSNEQHAIGEVVRKCGLCQESDMVLRKKPDGNFMVGCL 364
            ARLNK KL EAMAVFFERSN+S  ++ H  GEVVR+CGLC+ES MVL+K  DGNFMVGCL
Sbjct: 602  ARLNKVKLLEAMAVFFERSNQSAGDDNHVAGEVVRQCGLCRESSMVLKKNRDGNFMVGCL 661

Query: 363  GFPQCRNVVWLPGSVSEAIVTTNICSTCSPGPVYLIQFKFRRLEIPPNYNVNHLGCIGGC 184
            GFPQCRN +WLPGSV EA VT+NIC +C+PGPVYLIQFKFR+LEIPP +N NHLGCIGGC
Sbjct: 662  GFPQCRNAIWLPGSVLEAAVTSNICGSCNPGPVYLIQFKFRQLEIPPGFNANHLGCIGGC 721

Query: 183  DDILRQLVEVCGTGSR 136
            DDILRQL+E+CGTGSR
Sbjct: 722  DDILRQLIEICGTGSR 737


>ref|XP_012489371.1| PREDICTED: DNA topoisomerase 3-alpha isoform X4 [Gossypium raimondii]
            gi|763773368|gb|KJB40491.1| hypothetical protein
            B456_007G066700 [Gossypium raimondii]
            gi|763773370|gb|KJB40493.1| hypothetical protein
            B456_007G066700 [Gossypium raimondii]
          Length = 909

 Score = 1266 bits (3277), Expect = 0.0
 Identities = 595/736 (80%), Positives = 659/736 (89%)
 Frame = -1

Query: 2343 LRALNVAEKPSVAKAVSGILSKTPSSGGLRVRDGRSRYNRIFEFNYTIQNQQVHMSFTSV 2164
            ++ LNVAEKPSVAK+VSG LS+  +   LRVRDGRSRYNRIFEFNY+I+ Q  HM FTSV
Sbjct: 5    IKVLNVAEKPSVAKSVSGFLSRNQA---LRVRDGRSRYNRIFEFNYSIRGQPCHMLFTSV 61

Query: 2163 TGHLMELDFEDRYRKWHSCDPVDLYHAPVKKYVPEDKSEIEKTLEEEARKCQWLILWLDC 1984
            TGHLMEL+FEDR+RKWHSCDP+DLYHAPV+K+VPEDK +I++TLEEEAR+CQWL+LWLDC
Sbjct: 62   TGHLMELEFEDRFRKWHSCDPLDLYHAPVRKFVPEDKLDIKRTLEEEARRCQWLVLWLDC 121

Query: 1983 DREGENIAFEVVEVCTRANRNLNIWRARFSALIDREIHYSVQHLVRPNQLFSDAVDARQE 1804
            DREGENIAFEV+ VC   NR+L I RARFSALIDREIH+++Q+L+ PN  FSDAVDARQE
Sbjct: 122  DREGENIAFEVINVCRAVNRHLTIRRARFSALIDREIHHAMQNLIDPNPWFSDAVDARQE 181

Query: 1803 IDLRIGASFTRFQTMLLRDAFVLDFATDNTNVILSYGPCQFPTLGFIVERFWEVQSHEPE 1624
            IDLRIGASFTRFQTMLLRD FV+D ATD+ N++LSYGPCQFPTLGF+VER+WEVQSHEPE
Sbjct: 182  IDLRIGASFTRFQTMLLRDKFVIDSATDDRNLVLSYGPCQFPTLGFVVERYWEVQSHEPE 241

Query: 1623 EFWTINCTHNSEEGTATFNWMRGHLFDYTCAMIIYEMCVQEPTATVTNVRQQEKLKYPPH 1444
            EFWTINC+H S+EG ATFNWMRGHLFDYTCA+I+YEMCVQEPTATVT V+ +EKLKYPP+
Sbjct: 242  EFWTINCSHRSDEGVATFNWMRGHLFDYTCAVIVYEMCVQEPTATVTKVQHKEKLKYPPY 301

Query: 1443 PLSTIELEKRASRYFRMSSEHTMKVAEDLYQAGFISYPRTETDCFSVRTDLHTIVQEQQG 1264
            PL+TIELEKRASRYFRMSSEHTMKVAE+LYQAGFISYPRTETDCFS RTDLH IVQEQQG
Sbjct: 302  PLNTIELEKRASRYFRMSSEHTMKVAEELYQAGFISYPRTETDCFSSRTDLHAIVQEQQG 361

Query: 1263 HPVWGSYAQRLLDPEASLWRNPSGGGHDDKAHPPIHPTKFSAGESGWSPDHHKVYELVVR 1084
            HP WGSYAQRLLDPE  LWRNP  GGHDDKAHPPIHPTKFS GE GWS DH  +YELVVR
Sbjct: 362  HPDWGSYAQRLLDPETGLWRNPGSGGHDDKAHPPIHPTKFSTGEHGWSQDHRTLYELVVR 421

Query: 1083 HFLACVSQPAIGAETTVEIDIACEQFSASGRVIIAKNYLDVYRFETWGGSMIPTYNYGQQ 904
            HFLACVSQPA+GAETTVEIDIA E FSASGRVI+ +NYLDVYR+E+WGGSMIPTY  GQQ
Sbjct: 422  HFLACVSQPAVGAETTVEIDIAGELFSASGRVILERNYLDVYRYESWGGSMIPTYTVGQQ 481

Query: 903  FTPTTLTLDAGVTRPPPLLSEADLLSCMDKAGIGTDATMHDHIKKLLDRFYATKDSSMRF 724
            F P +LTLD GVTRPPPLLSEADLLSCMDKAGIGTDATMHDHIKKLLDRFYATKDS+ RF
Sbjct: 482  FVPASLTLDTGVTRPPPLLSEADLLSCMDKAGIGTDATMHDHIKKLLDRFYATKDSNTRF 541

Query: 723  SPTKLGEALVMGYDDMGYELWKPYLRAMMESDMKAVSMGTKRKAEVLEACLQQMKACFVD 544
            SPT LGEALVMGYDDMGYELWKP LR+MME DMK VS+G K K EVL  CLQQMKACF D
Sbjct: 542  SPTNLGEALVMGYDDMGYELWKPNLRSMMEFDMKEVSVGNKSKDEVLATCLQQMKACFFD 601

Query: 543  ARLNKGKLFEAMAVFFERSNRSNSNEQHAIGEVVRKCGLCQESDMVLRKKPDGNFMVGCL 364
            ARLNK KL EAMAVFFERSNR+   + +A GEVVR+C LCQES MVL+K  DGNFMVGC 
Sbjct: 602  ARLNKVKLLEAMAVFFERSNRAVGGDNYAAGEVVRQCDLCQESSMVLKKNRDGNFMVGCS 661

Query: 363  GFPQCRNVVWLPGSVSEAIVTTNICSTCSPGPVYLIQFKFRRLEIPPNYNVNHLGCIGGC 184
            GFPQCRN +WLPGS+ EA VT+NICS+C+PGPVYLIQFKFR++EIPP +N NHLGCIGGC
Sbjct: 662  GFPQCRNAIWLPGSILEAAVTSNICSSCNPGPVYLIQFKFRQIEIPPGFNANHLGCIGGC 721

Query: 183  DDILRQLVEVCGTGSR 136
            DD LRQL+E+CGTGSR
Sbjct: 722  DDTLRQLIEICGTGSR 737