BLASTX 2.2.25 [Feb-01-2011]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= Rehmannia23_contig00024278
         (2033 letters)

Database: ./nr 
           37,332,560 sequences; 13,225,080,153 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

ref|XP_002274267.1| PREDICTED: DNA topoisomerase 2-like [Vitis v...   348   5e-93
emb|CBI24922.3| unnamed protein product [Vitis vinifera]              339   2e-90
ref|XP_002517802.1| DNA topoisomerase II, putative [Ricinus comm...   333   2e-88
gb|EOY18137.1| DNA topoisomerase 2 isoform 1 [Theobroma cacao]        332   5e-88
gb|EOY18138.1| DNA topoisomerase 2 isoform 2 [Theobroma cacao]        330   1e-87
ref|XP_006345427.1| PREDICTED: DNA topoisomerase 2-like [Solanum...   327   9e-87
ref|XP_006439078.1| hypothetical protein CICLE_v10030505mg [Citr...   325   4e-86
ref|XP_002298421.2| DNA topoisomerase family protein [Populus tr...   325   4e-86
gb|AAN85207.1| DNA topoisomerase II [Nicotiana tabacum] gi|26984...   324   8e-86
ref|XP_006439079.1| hypothetical protein CICLE_v10030505mg [Citr...   321   9e-85
ref|XP_006482851.1| PREDICTED: DNA topoisomerase 2-like [Citrus ...   320   1e-84
ref|XP_004229644.1| PREDICTED: DNA topoisomerase 2-like [Solanum...   320   2e-84
gb|EMJ21781.1| hypothetical protein PRUPE_ppa000202mg [Prunus pe...   312   3e-82
gb|EOY18139.1| Topoisomerase II isoform 3 [Theobroma cacao]           310   1e-81
ref|XP_002314046.2| DNA topoisomerase family protein [Populus tr...   309   3e-81
gb|EXB68160.1| DNA topoisomerase 2 [Morus notabilis]                  303   2e-79
ref|XP_004308680.1| PREDICTED: DNA topoisomerase 2-like [Fragari...   291   7e-76
ref|XP_001758663.1| predicted protein [Physcomitrella patens] gi...   291   7e-76
ref|XP_001769043.1| predicted protein [Physcomitrella patens] gi...   291   1e-75
ref|XP_006838283.1| hypothetical protein AMTR_s00103p00101630 [A...   289   3e-75

>ref|XP_002274267.1| PREDICTED: DNA topoisomerase 2-like [Vitis vinifera]
          Length = 1489

 Score =  348 bits (893), Expect = 5e-93
 Identities = 233/587 (39%), Positives = 317/587 (54%), Gaps = 39/587 (6%)
 Frame = +2

Query: 2    MIPWYKGFKGTIESTN-TKDAGKSYVVKGIIEEVNKTTVRITELPVRKSTEEYKQFLDKL 178
            M PWY+GF+GTIE T+ TK     Y VKGIIEEVN+TT+RI+ELPVRK T++YK+FL+ +
Sbjct: 871  MDPWYRGFRGTIEKTDPTKQESVGYTVKGIIEEVNETTLRISELPVRKWTQDYKEFLESI 930

Query: 179  ISKGGRNKEQFIKDFREFNDDKTVHFEIYMSEKNLAMAKEEGLIEKFKLSTTISTSNMHL 358
            ++   + K+ FIKD++E NDD TVHFE+ MSE+NL MAK+EGL++KFKL+T ISTSNMHL
Sbjct: 931  MTGNDKIKDPFIKDYKEHNDDTTVHFEVIMSEENLLMAKQEGLLQKFKLTTKISTSNMHL 990

Query: 359  FNPKRVLAKYSSPEKIIEEFCDLRLEFYEKRKIFMLSMXXXXXXXXXNKVRFIDEVIQGK 538
            F+    + KY +PE+I+EEF  LRLEFYEKRK  +L           NKVRFI  V++G+
Sbjct: 991  FDSNGTIKKYETPEQILEEFFHLRLEFYEKRKRVLLDNLELELLKLENKVRFILGVVRGE 1050

Query: 539  IILMNRKRSDLLDELKQKNFTPFPRNA--------------------XXXXXXXXXXXXX 658
            II+ NRKR+DL  EL QK FTPFP+ +                                 
Sbjct: 1051 IIVSNRKRADLFHELHQKGFTPFPKKSKSVEIAVAGATDDTEEAEENTDAVSKGGVRATD 1110

Query: 659  YEYLLSMPIGTLTMEKVQELCAQRKKLNVEVDGLRHATPKSLWLKDLDSLEQKLNLQSKI 838
            YEYLLSM IGTLT+EKVQELCA R KLN  VD L+ ATPK+LW+ DLD+LE++L+ Q K 
Sbjct: 1111 YEYLLSMAIGTLTLEKVQELCADRDKLNKGVDDLKKATPKALWITDLDALERELDEQDKN 1170

Query: 839  YDMPEK-----RLEVNAEISKRPKRTMRKKQESSEKKANNKDGLAEKHTVPSDCT---GK 994
                E+     +  V +E   +  R   K    + KKANN +  AE   V +        
Sbjct: 1171 DARAEETRKQLKSRVMSEAGMKVSRQAPKNPRKNNKKANNAEPAAETMDVSASSAMEMES 1230

Query: 995  VPEAVELEGITTGR------DEISTPNPPSLDVNEDRGPKQKEEQPKQSSSPDTSREPKM 1156
            VPE V+ +G    R       E+ T      D +E    K++       SSPD S   + 
Sbjct: 1231 VPEVVKPKGRAAPRKAPAKKKEMPTSVLKDEDDDEVHELKERLAAYNLESSPDGSAAMEA 1290

Query: 1157 SVLQVP---PEDNTRRNSADNLN-APIIEISDTEVDCENKQQTAETVIEISDSEVVCEDE 1324
             V QVP    ++ +RR +A     A   EISD + D E+ +     V E+S S+V  +  
Sbjct: 1291 EVPQVPAARKKEPSRRAAAQKKPLASFTEISDDDEDDEDFE-----VEEVSASDVKKKGG 1345

Query: 1325 VPNTRINNPSGDEKLEDQIASTVESGMTSVDKTSQENKNRHVMITRKRANMSRQNGATSL 1504
                    P+ + K     A+   +   + +K    NK +  ++           G T L
Sbjct: 1346 ------RKPAANAK----AAAAKPAAAAAKNKRGAANKQQPQLL-----------GQTLL 1384

Query: 1505 ANGSSGSVLKAVENIMVSPEKKLRRTSSFPFRKKKNYSPTKNGQNKE 1645
                   + K  E + +SPEKK+R+  + PF KK        G+  E
Sbjct: 1385 T-----EIFKPAETLGISPEKKVRKMRASPFNKKSGSVLGSTGEEDE 1426


>emb|CBI24922.3| unnamed protein product [Vitis vinifera]
          Length = 1452

 Score =  339 bits (870), Expect = 2e-90
 Identities = 228/567 (40%), Positives = 310/567 (54%), Gaps = 19/567 (3%)
 Frame = +2

Query: 2    MIPWYKGFKGTIESTN-TKDAGKSYVVKGIIEEVNKTTVRITELPVRKSTEEYKQFLDKL 178
            M PWY+GF+GTIE T+ TK     Y VKGIIEEVN+TT+RI+ELPVRK T++YK+FL+ +
Sbjct: 871  MDPWYRGFRGTIEKTDPTKQESVGYTVKGIIEEVNETTLRISELPVRKWTQDYKEFLESI 930

Query: 179  ISKGGRNKEQFIKDFREFNDDKTVHFEIYMSEKNLAMAKEEGLIEKFKLSTTISTSNMHL 358
            ++   + K+ FIKD++E NDD TVHFE+ MSE+NL MAK+EGL++KFKL+T ISTSNMHL
Sbjct: 931  MTGNDKIKDPFIKDYKEHNDDTTVHFEVIMSEENLLMAKQEGLLQKFKLTTKISTSNMHL 990

Query: 359  FNPKRVLAKYSSPEKIIEEFCDLRLEFYEKRKIFMLSMXXXXXXXXXNKVRFIDEVIQGK 538
            F+    + KY +PE+I+EEF  LRLEFYEKRK  +L           NKVRFI  V++G+
Sbjct: 991  FDSNGTIKKYETPEQILEEFFHLRLEFYEKRKRVLLDNLELELLKLENKVRFILGVVRGE 1050

Query: 539  IILMNRKRSDLLDELKQKNFTPFPRNAXXXXXXXXXXXXXYEYLLSMPIGTLTMEKVQEL 718
            II+ NRKR+DL  EL QK                      YEYLLSM IGTLT+EKVQEL
Sbjct: 1051 IIVSNRKRADLFHELHQK-----------------VRATDYEYLLSMAIGTLTLEKVQEL 1093

Query: 719  CAQRKKLNVEVDGLRHATPKSLWLKDLDSLEQKLNLQSKIYDMPEK-----RLEVNAEIS 883
            CA R KLN  VD L+ ATPK+LW+ DLD+LE++L+ Q K     E+     +  V +E  
Sbjct: 1094 CADRDKLNKGVDDLKKATPKALWITDLDALERELDEQDKNDARAEETRKQLKSRVMSEAG 1153

Query: 884  KRPKRTMRKKQESSEKKANNKDGLAEKHTVPSDCT---GKVPEAVELEGITTGR------ 1036
             +  R   K    + KKANN +  AE   V +        VPE V+ +G    R      
Sbjct: 1154 MKVSRQAPKNPRKNNKKANNAEPAAETMDVSASSAMEMESVPEVVKPKGRAAPRKAPAKK 1213

Query: 1037 DEISTPNPPSLDVNEDRGPKQKEEQPKQSSSPDTSREPKMSVLQVP---PEDNTRRNSAD 1207
             E+ T      D +E    K++       SSPD S   +  V QVP    ++ +RR +A 
Sbjct: 1214 KEMPTSVLKDEDDDEVHELKERLAAYNLESSPDGSAAMEAEVPQVPAARKKEPSRRAAAQ 1273

Query: 1208 NLN-APIIEISDTEVDCENKQQTAETVIEISDSEVVCEDEVPNTRINNPSGDEKLEDQIA 1384
                A   EISD + D E+ +     V E+S S+V  +          P+ + K     A
Sbjct: 1274 KKPLASFTEISDDDEDDEDFE-----VEEVSASDVKKKGG------RKPAANAK----AA 1318

Query: 1385 STVESGMTSVDKTSQENKNRHVMITRKRANMSRQNGATSLANGSSGSVLKAVENIMVSPE 1564
            +   +   + +K    NK +  ++           G T L       + K  E + +SPE
Sbjct: 1319 AAKPAAAAAKNKRGAANKQQPQLL-----------GQTLLT-----EIFKPAETLGISPE 1362

Query: 1565 KKLRRTSSFPFRKKKNYSPTKNGQNKE 1645
            KK+R+  + PF KK        G+  E
Sbjct: 1363 KKVRKMRASPFNKKSGSVLGSTGEEDE 1389


>ref|XP_002517802.1| DNA topoisomerase II, putative [Ricinus communis]
            gi|223543074|gb|EEF44609.1| DNA topoisomerase II,
            putative [Ricinus communis]
          Length = 1212

 Score =  333 bits (854), Expect = 2e-88
 Identities = 226/580 (38%), Positives = 310/580 (53%), Gaps = 45/580 (7%)
 Frame = +2

Query: 2    MIPWYKGFKGTIESTNTKDAGKSYVVKGIIEEVNKTTVRITELPVRKSTEEYKQFLDKLI 181
            M PWYKGFKGTIE + +K+ G SY V GIIEEVN+TTVRITELP+R+ T+EYK FL+ +I
Sbjct: 586  MHPWYKGFKGTIEKSASKEGGGSYAVNGIIEEVNETTVRITELPIRRWTDEYKDFLNSVI 645

Query: 182  S-----KGGRNKEQFIKDFREFNDDKTVHFEIYMSEKNLAMAKEEGLIEKFKLSTTISTS 346
                  KG   K+ FIKDFR++ DD +V FE+ +SE+ +   K+EGL++KFKL+TTISTS
Sbjct: 646  ENVRDEKGNLPKDAFIKDFRKYGDDVSVCFEVLLSEEKMKQVKDEGLLKKFKLATTISTS 705

Query: 347  NMHLFNPKRVLAKYSSPEKIIEEFCDLRLEFYEKRKIFMLSMXXXXXXXXXNKVRFIDEV 526
            NMHLF+PK V+ KY SPE+I+EEF  LR E YEKRK F L+          NKVRFI  V
Sbjct: 706  NMHLFDPKGVIKKYDSPEEILEEFVHLRFELYEKRKNFKLASLEMEALILENKVRFILGV 765

Query: 527  IQGKIILMNRKRSDLLDELKQKNFTPFPRNA---------------------XXXXXXXX 643
            + G+II+ NRKR++LL EL+QK FTPFP+N                              
Sbjct: 766  VTGEIIVNNRKRAELLLELRQKGFTPFPKNKPVEAVVAGAADDTEESESTEDVEENSKTG 825

Query: 644  XXXXXYEYLLSMPIGTLTMEKVQELCAQRKKLNVEVDGLRHATPKSLWLKDLDSLEQKLN 823
                 YEYLLSM IGTLT+EKVQ+LCA + K++ EV+ LR   PK LWLKDL++ E +L+
Sbjct: 826  VQATDYEYLLSMSIGTLTLEKVQKLCADKDKISEEVENLRRTAPKDLWLKDLEAFESQLD 885

Query: 824  LQSKIYDMPEKRLEV-------NAEISKRPKRTMRKKQESSEKKANNKDGLAEKHTVPSD 982
             +    D  E++  V         ++S++P +  RK    + K A N +  AE     S+
Sbjct: 886  -KLDAEDALERQKSVKDTNGQGGFKVSRQPPKNPRK----NNKTAKNTEAAAEIMGQTSN 940

Query: 983  C---TGKVPEAVELEGITTGR----DEISTPNPPSLDVNED-RGPKQKEEQPKQSSSPDT 1138
                T  V E V+ +G    +     +   P P S D +++    K + +  +  SSP+ 
Sbjct: 941  SAMETESVSEEVKPKGRAASKKAPAKKQEKPTPISDDEDDEVEALKDRLKAYRLDSSPEQ 1000

Query: 1139 SREPKMSVLQVPPEDNTRRNSADNLN--APIIEISDT--EVDCENKQQTAETVIEISDSE 1306
            S   +  + QVP    T + +A      A I E+S++  EVD +++          SD E
Sbjct: 1001 STTMETDMPQVPARKETSKRAAAQKKPVATISELSESEDEVDLDDE----------SDVE 1050

Query: 1307 VVCEDEVPNTRINNPSGDEKLEDQIASTVESGMTSVDKTSQENKNRHVMITRKRANMSRQ 1486
            VV   E        P+ + +     A T + G T   K SQ                   
Sbjct: 1051 VVPVPEAKKKGGRKPAANSRAAKPPAGTKKRGPTK--KESQ------------------- 1089

Query: 1487 NGATSLANGSSGSVLKAVENIMVSPEKKLRRTSSFPFRKK 1606
                 L       +LK  EN  +SPEKK+R+  + PF KK
Sbjct: 1090 ----GLGQKLLTEMLKPAENPGISPEKKVRKMRASPFNKK 1125


>gb|EOY18137.1| DNA topoisomerase 2 isoform 1 [Theobroma cacao]
          Length = 1473

 Score =  332 bits (850), Expect = 5e-88
 Identities = 221/576 (38%), Positives = 307/576 (53%), Gaps = 27/576 (4%)
 Frame = +2

Query: 2    MIPWYKGFKGTIESTNTKDAGKSYVVKGIIEEVNKTTVRITELPVRKSTEEYKQFLDKLI 181
            M PWY+GFKG IE T +K+AG +Y + GIIEEV++TT+RITELPVR+ T++Y++FL+ +I
Sbjct: 868  MHPWYRGFKGNIEKTASKEAGVTYTITGIIEEVDETTLRITELPVRRWTQDYREFLESII 927

Query: 182  SKGGRNKEQFIKDFREFNDDKTVHFEIYMSEKNLAMAKEEGLIEKFKLSTTISTSNMHLF 361
            +      + FIK+FR+++DD TV FE+ ++E+N+ +AK+EGL++KFKL+TTISTSNMHLF
Sbjct: 928  T----GNDPFIKEFRQYSDDTTVEFEVILTEENMMVAKQEGLLKKFKLTTTISTSNMHLF 983

Query: 362  NPKRVLAKYSSPEKIIEEFCDLRLEFYEKRKIFMLSMXXXXXXXXXNKVRFIDEVIQGKI 541
            + K ++ KY +PE+I+EEF  LR EFYEKRK  +L           NKVRFI  V++G+I
Sbjct: 984  DSKGMIKKYDTPEQILEEFFHLRFEFYEKRKKLLLDNLEMELLKMENKVRFILGVVKGEI 1043

Query: 542  ILMNRKRSDLLDELKQKNFTPFPRNA-------------------XXXXXXXXXXXXXYE 664
            I+ NRKR+DL  EL+ K FTPFP+ A                                Y+
Sbjct: 1044 IVNNRKRADLFLELQTKGFTPFPKKAKTVEVAVAGATDDTEETEENSEVSAKGLQASDYD 1103

Query: 665  YLLSMPIGTLTMEKVQELCAQRKKLNVEVDGLRHATPKSLWLKDLDSLEQKLNLQSKIYD 844
            YLLSM IG+LT+EKVQELCA R KL  EV+ LR ATPKSLWLKDLD+LE +L+ Q K   
Sbjct: 1104 YLLSMAIGSLTLEKVQELCADRDKLQQEVEDLRKATPKSLWLKDLDNLEIQLDEQDKAAQ 1163

Query: 845  MPE--KRLEVNAEISKRPKRTMRKKQESSEKKANNKDGLAEKHTVPSDC---TGKVPEAV 1009
              E  K ++   E  KR +R   K      KK  N + + E   + S     T   P AV
Sbjct: 1164 AEEAAKLVKGRGEAGKRAQRQAPKIPRKINKKEKNAETVTETTDISSSSAMETETAPAAV 1223

Query: 1010 ELEGITTGRDEISTPNPPSLDVNEDRG-PKQKEEQPKQS--SSPDTSREPKMSVLQVPPE 1180
            + +G   G    +  +    D +ED G P  +E   K +  SSPD S   +  V QVP  
Sbjct: 1224 KPKG--RGGSRKAKKDDSDDDDDEDFGIPDLRERLAKYNLDSSPDHSAAMETEVPQVP-- 1279

Query: 1181 DNTRRNSADNLNAPIIEISDTEVDCENKQQTAETVIEISDSEVVCEDEVPNTRINNPSGD 1360
                        A   E S        K  T+ + I  S  E+   DE           D
Sbjct: 1280 ------------AGKKEPSKRAAAARKKPATSLSEISESIGEIDINDE-----------D 1316

Query: 1361 EKLEDQIASTVESGMTSVDKTSQENKNRHVMITRKRANMSRQNGATSLANGSSGSVLKAV 1540
             ++ +  A+   +G     K +  +K         +       G  S        +LK  
Sbjct: 1317 LEVVEVAAAAAPAGKKGGRKPAANSKAAAKPPAAAKKRGPAAAGKKSQQQKLLTEMLKPA 1376

Query: 1541 ENIMVSPEKKLRRTSSFPFRKKKNYSPTKNGQNKEN 1648
            E+  +SPEKK+R+  + PF KK      + G+  E+
Sbjct: 1377 EDSGISPEKKVRKMRASPFNKKSGSVLGRVGKELES 1412


>gb|EOY18138.1| DNA topoisomerase 2 isoform 2 [Theobroma cacao]
          Length = 1285

 Score =  330 bits (846), Expect = 1e-87
 Identities = 220/577 (38%), Positives = 307/577 (53%), Gaps = 28/577 (4%)
 Frame = +2

Query: 2    MIPWYKGFKGTIESTNTKDAGKSYVVKGIIEEVNKTTVRITELPVRKSTEEYKQFLDKLI 181
            M PWY+GFKG IE T +K+AG +Y + GIIEEV++TT+RITELPVR+ T++Y++FL+ +I
Sbjct: 679  MHPWYRGFKGNIEKTASKEAGVTYTITGIIEEVDETTLRITELPVRRWTQDYREFLESII 738

Query: 182  SKGGRNKEQFIKDFREFNDDKTVHFEIYMSEKNLAMAKEEGLIEKFKLSTTISTSNMHLF 361
            +      + FIK+FR+++DD TV FE+ ++E+N+ +AK+EGL++KFKL+TTISTSNMHLF
Sbjct: 739  T----GNDPFIKEFRQYSDDTTVEFEVILTEENMMVAKQEGLLKKFKLTTTISTSNMHLF 794

Query: 362  NPKRVLAKYSSPEKIIEEFCDLRLEFYEKRKIFMLSMXXXXXXXXXNKVRFIDEVIQGKI 541
            + K ++ KY +PE+I+EEF  LR EFYEKRK  +L           NKVRFI  V++G+I
Sbjct: 795  DSKGMIKKYDTPEQILEEFFHLRFEFYEKRKKLLLDNLEMELLKMENKVRFILGVVKGEI 854

Query: 542  ILMNRKRSDLLDELKQKNFTPFPRNA-------------------XXXXXXXXXXXXXYE 664
            I+ NRKR+DL  EL+ K FTPFP+ A                                Y+
Sbjct: 855  IVNNRKRADLFLELQTKGFTPFPKKAKTVEVAVAGATDDTEETEENSEVSAKGLQASDYD 914

Query: 665  YLLSMPIGTLTMEKVQELCAQRKKLNVEVDGLRHATPKSLWLKDLDSLEQKLNLQSKIYD 844
            YLLSM IG+LT+EKVQELCA R KL  EV+ LR ATPKSLWLKDLD+LE +L+ Q K   
Sbjct: 915  YLLSMAIGSLTLEKVQELCADRDKLQQEVEDLRKATPKSLWLKDLDNLEIQLDEQDKAAQ 974

Query: 845  MPE--KRLEVNAEISKRPKRTMRKKQESSEKKANNKDGLAEKHTVPS----DCTGKVPEA 1006
              E  K ++   E  KR +R   K      KK  N + + E   + S    +     P A
Sbjct: 975  AEEAAKLVKGRGEAGKRAQRQAPKIPRKINKKEKNAETVTETTDISSSSAMETAETAPAA 1034

Query: 1007 VELEGITTGRDEISTPNPPSLDVNEDRG-PKQKEEQPKQS--SSPDTSREPKMSVLQVPP 1177
            V+ +G   G    +  +    D +ED G P  +E   K +  SSPD S   +  V QVP 
Sbjct: 1035 VKPKG--RGGSRKAKKDDSDDDDDEDFGIPDLRERLAKYNLDSSPDHSAAMETEVPQVP- 1091

Query: 1178 EDNTRRNSADNLNAPIIEISDTEVDCENKQQTAETVIEISDSEVVCEDEVPNTRINNPSG 1357
                         A   E S        K  T+ + I  S  E+   DE           
Sbjct: 1092 -------------AGKKEPSKRAAAARKKPATSLSEISESIGEIDINDE----------- 1127

Query: 1358 DEKLEDQIASTVESGMTSVDKTSQENKNRHVMITRKRANMSRQNGATSLANGSSGSVLKA 1537
            D ++ +  A+   +G     K +  +K         +       G  S        +LK 
Sbjct: 1128 DLEVVEVAAAAAPAGKKGGRKPAANSKAAAKPPAAAKKRGPAAAGKKSQQQKLLTEMLKP 1187

Query: 1538 VENIMVSPEKKLRRTSSFPFRKKKNYSPTKNGQNKEN 1648
             E+  +SPEKK+R+  + PF KK      + G+  E+
Sbjct: 1188 AEDSGISPEKKVRKMRASPFNKKSGSVLGRVGKELES 1224


>ref|XP_006345427.1| PREDICTED: DNA topoisomerase 2-like [Solanum tuberosum]
          Length = 1485

 Score =  327 bits (839), Expect = 9e-87
 Identities = 218/592 (36%), Positives = 312/592 (52%), Gaps = 23/592 (3%)
 Frame = +2

Query: 2    MIPWYKGFKGTIESTNTKDAGKSYVVKGIIEEVNKTTVRITELPVRKSTEEYKQFLDKLI 181
            M PWYKGFKGTIE T TK+ G +Y V GIIEE ++TT+RI+ELPVR+ TE+YKQFL+ + 
Sbjct: 868  MDPWYKGFKGTIEKTATKETGATYTVTGIIEEFSETTLRISELPVRRWTEDYKQFLESMT 927

Query: 182  SKGGRNKEQFIKDFREFNDDKTVHFEIYMSEKNLAMAKEEGLIEKFKLSTTISTSNMHLF 361
                ++K+ FIK+ R + D+ +V FE+ MSE+NL +A++EGL++KFKL+TTISTSNMHLF
Sbjct: 928  VSTDKSKDAFIKEVRAYGDENSVCFEVIMSEENLLLAQQEGLLKKFKLTTTISTSNMHLF 987

Query: 362  NPKRVLAKYSSPEKIIEEFCDLRLEFYEKRKIFMLSMXXXXXXXXXNKVRFIDEVIQGKI 541
            + K  + KY +PE+I+EEF  +RLE+YEKRK  +L +         NKVRFI  V++G+I
Sbjct: 988  DSKGKIKKYDAPEEILEEFYHVRLEYYEKRKKTLLEILELELLRIENKVRFILGVVKGEI 1047

Query: 542  ILMNRKRSDLLDELKQKNFTPFPR------------------NAXXXXXXXXXXXXXYEY 667
            I+ NRKR+DLL ELK K FTPFP+                                 Y+Y
Sbjct: 1048 IVNNRKRADLLLELKNKGFTPFPKKKPVEAVVADSTDDAEDSEESPEESNKGVRASDYDY 1107

Query: 668  LLSMPIGTLTMEKVQELCAQRKKLNVEVDGLRHATPKSLWLKDLDSLEQKLNLQSKIYDM 847
            LLSM IGTLT+EKVQELCA R KLN EV+ +R+ATPK LW+KDLD L+++L+ Q K+   
Sbjct: 1108 LLSMAIGTLTLEKVQELCADRDKLNAEVEDMRNATPKDLWMKDLDVLDKQLDEQDKLDIQ 1167

Query: 848  PEKRLEVNAEISKRPKRTMRKKQESSEKKANNKDGLAEKHTVPSDCTGKVPEAVELEGIT 1027
             E   E   ++ K+      K  +   +K   K  + E    P D +  V    E   +T
Sbjct: 1168 TE---EAREKLKKKVMNAAGKAPKPKPRKTTKKAAVVESTAEPMDVS--VGSMAETANVT 1222

Query: 1028 TGRDEISTPNPPSLDVNEDRGPKQKEEQPKQSSSPDTSREPKMSVLQVPPEDNTRRNSAD 1207
                E++ P           G K+   + K     D   E ++  L+        R +A 
Sbjct: 1223 ----EVAKPK------GRGGGSKKAPAKAKPVVVEDEEEEDEVLALK-------DRLAAY 1265

Query: 1208 NLNAPIIEISDTEVDCENKQQTAETVIEISDSEVVCEDEVPNTRINNPSGDE-KLEDQIA 1384
            NLN+       TE +    Q  A      +  +      +P+T   +   DE ++ D   
Sbjct: 1266 NLNSSPDRSEVTETEAPKAQTKAPAKRAAAQKKA-----LPSTPDVSEGEDEIEISDDNE 1320

Query: 1385 STVESGMTSVDKTSQENKNRHVMIT----RKRANMSRQNGATSLANGSSGSVLKAVENIM 1552
               E  +    K  ++             +KRA  ++Q  + S+       VLK  E+  
Sbjct: 1321 FAPEVAVGGKKKGGRKPAAAKAAAAPKPPKKRAPANKQ--SQSVGQRLITQVLKPAEDAG 1378

Query: 1553 VSPEKKLRRTSSFPFRKKKNYSPTKNGQNKENYPSRCKESNLRNTV*LIASL 1708
            VSP++K+R+    PF KK   S    G+N  +  S   ES +   +  + SL
Sbjct: 1379 VSPDRKVRKMRESPFNKK---SGAVMGRNTSSSSSTSHESEVSPPIPSLGSL 1427


>ref|XP_006439078.1| hypothetical protein CICLE_v10030505mg [Citrus clementina]
            gi|557541274|gb|ESR52318.1| hypothetical protein
            CICLE_v10030505mg [Citrus clementina]
          Length = 1455

 Score =  325 bits (834), Expect = 4e-86
 Identities = 214/568 (37%), Positives = 306/568 (53%), Gaps = 33/568 (5%)
 Frame = +2

Query: 2    MIPWYKGFKGTIESTNTKDAGKSYVVKGIIEEVNKTTVRITELPVRKSTEEYKQFLDKLI 181
            M PWY+GF+GTIE T +K+AG +Y V GIIEEVN+TT+RI ELP+R+ T++Y++FL+ +I
Sbjct: 867  MHPWYRGFRGTIEKTASKEAGVTYTVTGIIEEVNETTLRIKELPIRRWTQDYREFLESII 926

Query: 182  SKGGRNKEQFIKDFREFNDDKTVHFEIYMSEKNLAMAKEEGLIEKFKLSTTISTSNMHLF 361
             +     + FI+ FR+++DD TV FE+++SE+++   K+EGL++KFKL+TTISTSNMHLF
Sbjct: 927  DQN----DSFIRGFRQYSDDTTVDFEVFLSEESMMRTKQEGLLKKFKLTTTISTSNMHLF 982

Query: 362  NPKRVLAKYSSPEKIIEEFCDLRLEFYEKRKIFMLSMXXXXXXXXXNKVRFIDEVIQGKI 541
            + K V+ KY +PE+I+EEF  +RLEFYEKRK   L           NKVRFI  V+ G+I
Sbjct: 983  DSKGVIKKYDTPEQILEEFFHIRLEFYEKRKKVQLENLELELLKLENKVRFILGVVNGEI 1042

Query: 542  ILMNRKRSDLLDELKQKNFTPFPRNA------------------XXXXXXXXXXXXXYEY 667
            ++ NRKR+DLL EL+QK FTPFP+N+                               Y+Y
Sbjct: 1043 VVNNRKRTDLLLELRQKGFTPFPKNSKSIEAVVAGATDETEESEENPEVVNGVQSIDYDY 1102

Query: 668  LLSMPIGTLTMEKVQELCAQRKKLNVEVDGLRHATPKSLWLKDLDSLEQKLNLQSKIYDM 847
            LLSM IGTLT+EKVQ L A R KLN EVD LR ATP+SLW+KDLD+L+ +L+L       
Sbjct: 1103 LLSMAIGTLTLEKVQGLLADRDKLNEEVDDLRKATPESLWVKDLDALDMQLDLDKSDARA 1162

Query: 848  PEKRLEV--NAEISKRPK---RTMRKKQESSEKKANN---KDGLAEKHTV-----PSDCT 988
             E+R+++  N      PK   +   K    ++KK+NN    + + E   V     P    
Sbjct: 1163 EEERMKIKGNGNSDAGPKIVAKRAPKNARKNDKKSNNARATEAMGEMDNVTKVVKPKGRA 1222

Query: 989  G-KVPEAVELEGITTGRDEISTPNPPSLDVNEDRGPKQKEEQPKQSSSPDTSREPKMSVL 1165
            G K   A +L+      DE+         +NE     + E  P QS   +T +      +
Sbjct: 1223 GLKKAPAEKLD--DEEEDEVPDLKQRLAKLNEQLASTKLEPSPDQSGVMETEK------V 1274

Query: 1166 QVP-PEDNTRRNSADNLNAPIIEISDTEVDCENKQQTAETVIEISDSEVVCEDEVPNTRI 1342
            QVP  +    + +A    A  +E SD+E                 D  ++ +DE     I
Sbjct: 1275 QVPAKKKEPSKRTAAQKKAVTVETSDSE-----------------DEIIIDDDEA--FEI 1315

Query: 1343 NNPSGDEKLEDQIASTVESGMTSVDKTSQENKNRHVMITRKRANMSRQNGATSLANGSSG 1522
              P   +K   + A   ++   +V+             T+KR    +Q    SL      
Sbjct: 1316 AAPEAGKKGGRKAAGNTKAAKPAVE-------------TKKRGPAKKQQPEASLGQRLLT 1362

Query: 1523 SVLKAVENIMVSPEKKLRRTSSFPFRKK 1606
             +LK  E+   SPEKK+R+  + PF KK
Sbjct: 1363 EMLKPTES---SPEKKVRKMRASPFNKK 1387


>ref|XP_002298421.2| DNA topoisomerase family protein [Populus trichocarpa]
            gi|550348289|gb|EEE83226.2| DNA topoisomerase family
            protein [Populus trichocarpa]
          Length = 1485

 Score =  325 bits (834), Expect = 4e-86
 Identities = 214/563 (38%), Positives = 301/563 (53%), Gaps = 28/563 (4%)
 Frame = +2

Query: 2    MIPWYKGFKGTIESTNTKDAGKSYVVKGIIEEVNKTTVRITELPVRKSTEEYKQFLDKLI 181
            M PWY+GFKGTIE   +K+AG SY V G+I EVN+TT+RITELP+R+ T++YK FL+  +
Sbjct: 885  MNPWYRGFKGTIEKGASKEAGCSYTVNGVINEVNETTLRITELPIRRWTDDYKAFLNS-V 943

Query: 182  SKGGRN------KEQFIKDFREFNDDKTVHFEIYMSEKNLAMAKEEGLIEKFKLSTTIST 343
            ++G R+      K+ FIKDFR++ DD TV FE+ +SE+N+ +AK+EGL++KFKL+TTIST
Sbjct: 944  TEGNRDENGNLPKDPFIKDFRKYGDDATVVFEVLLSEENMMIAKQEGLLKKFKLTTTIST 1003

Query: 344  SNMHLFNPKRVLAKYSSPEKIIEEFCDLRLEFYEKRKIFMLSMXXXXXXXXXNKVRFIDE 523
            SNMHLF+   V+ KY +PE+I+EEF  LRLE+YE+RK  +L           NKVRFI  
Sbjct: 1004 SNMHLFDSAGVIKKYDNPEQILEEFFHLRLEYYERRKKVLLENLEFELLKLENKVRFILG 1063

Query: 524  VIQGKIILMNRKRSDLLDELKQKNFTPFPR--------------NAXXXXXXXXXXXXXY 661
            V++G+II+ NRKR+DL  EL QK FTP P+               A             Y
Sbjct: 1064 VVRGEIIVNNRKRADLFLELHQKGFTPIPKKSKAVVAGATDDKDEAEDSLEVSGVRASDY 1123

Query: 662  EYLLSMPIGTLTMEKVQELCAQRKKLNVEVDGLRHATPKSLWLKDLDSLEQKLNLQSKIY 841
            +YLLSM IGTLT+EKVQ+LCA   KLN EVD LR  TP  LW+KDL++LE +L++  K Y
Sbjct: 1124 DYLLSMAIGTLTLEKVQQLCADHDKLNGEVDNLRKTTPIVLWVKDLEALEMQLDVLDK-Y 1182

Query: 842  DM----PEKRL--EVNAEISKRPKRTMRKKQESSEKKANNKDGLAEKHTVPSDCTGKVPE 1003
            D       K+L  + N E   +  +   K      KKA N++   E     S    +   
Sbjct: 1183 DAEAEEARKKLKGDANGEAGFKVSKQAPKNPRKYTKKAINEEVSVETMGKASSSAMETEN 1242

Query: 1004 AVELEGITTGRDEISTPNPPSLDVNEDRGPKQKEEQPKQSSSPDTSREPKMSVLQVPPED 1183
            A E+               P       + P +K+E+P   S  D   E     L+    D
Sbjct: 1243 AAEVV-------------KPKGRAGSRKAPAKKQEKPSPISDEDDEIESLKDRLKAYRLD 1289

Query: 1184 NTRRNSADNLNAPIIEISDTEVDCENKQQTAETVIEISDSEVVCEDEVPNTRINNPSGDE 1363
            ++   SAD +   ++ +         K   A +V  ISDSE            + P  D+
Sbjct: 1290 SSPEQSAD-METEVLRVPAGRKAARKKPLAAVSV--ISDSE------------DEPDLDD 1334

Query: 1364 KLEDQIASTVESGMTSVDKTSQENKN--RHVMITRKRANMSRQNGATSLANGSSGSVLKA 1537
              + Q+ +  E+      K +  N    +    T++R   S+Q  +  L       +LK 
Sbjct: 1335 DFDVQVKAVPETKKKGGRKAAAANDKAAKPPAATKRRGPASKQ--SQGLGQQLLTEMLKP 1392

Query: 1538 VENIMVSPEKKLRRTSSFPFRKK 1606
             E   +SPEKK+R+  + PF KK
Sbjct: 1393 AEESGISPEKKVRKMRASPFNKK 1415


>gb|AAN85207.1| DNA topoisomerase II [Nicotiana tabacum] gi|26984168|gb|AAN85208.1|
            DNA topoisomerase II [Nicotiana tabacum]
          Length = 1482

 Score =  324 bits (831), Expect = 8e-86
 Identities = 215/571 (37%), Positives = 306/571 (53%), Gaps = 28/571 (4%)
 Frame = +2

Query: 2    MIPWYKGFKGTIESTNTKDAGKSYVVKGIIEEVNKTTVRITELPVRKSTEEYKQFLDKLI 181
            M PWYKGFKGTIE T TK+AG +Y V GIIEEVN+TT+RI+ELPVR+ TE+YKQFL+ + 
Sbjct: 867  MDPWYKGFKGTIEKTATKEAGATYTVTGIIEEVNETTLRISELPVRRWTEDYKQFLESMT 926

Query: 182  SKGGRNKEQFIKDFREFNDDKTVHFEIYMSEKNLAMAKEEGLIEKFKLSTTISTSNMHLF 361
                + K+ FIK+ R + D+ +V FE+ MSE+NL +A++EGL++KFKL+TTISTSNMHLF
Sbjct: 927  VSNDKAKDPFIKEVRAYGDENSVCFEVIMSEENLILAQQEGLLKKFKLATTISTSNMHLF 986

Query: 362  NPKRVLAKYSSPEKIIEEFCDLRLEFYEKRKIFMLSMXXXXXXXXXNKVRFIDEVIQGKI 541
            +    + KY +PE I+EEF  +RLE+YEKRK  +L +         NKV+FI  V++ +I
Sbjct: 987  DSNGKIKKYDNPEDILEEFYHVRLEYYEKRKKALLEILELELLRIENKVKFILGVVKVEI 1046

Query: 542  ILMNRKRSDLLDELKQKNFTPFPRNA---------------XXXXXXXXXXXXXYEYLLS 676
            I+ NRKR+DLL ELK+K FTPFP+                              Y+YLLS
Sbjct: 1047 IVNNRKRADLLLELKEKGFTPFPKKKAVEAVVADTSDDAEDSEEELNRGVRAGDYDYLLS 1106

Query: 677  MPIGTLTMEKVQELCAQRKKLNVEVDGLRHATPKSLWLKDLDSLEQKLNLQSKIYDMPE- 853
            MPIGTLT+EKVQELCA+R +LN EV+ +R+ATPK LWLKDLD LE++L+ Q KI    E 
Sbjct: 1107 MPIGTLTLEKVQELCAERDQLNGEVEDMRNATPKLLWLKDLDVLEKQLDEQDKIDIQAEE 1166

Query: 854  -----KRLEVNAEISKRPKRTMRKKQESSEKKANNKDGLAEKHTVPSDCTGKVPEAVELE 1018
                 K+  +NA   K PK   RK  + +    +  + +       S     V E V+ +
Sbjct: 1167 AREKIKKKVMNAAGLKAPKPKPRKNVKKASVVESTAEPMDRVSCFNSGNRSNVTEVVKPK 1226

Query: 1019 GITTGRDEISTPNPPSLDVNEDR------GPKQKEEQPKQSSSPDTSREPKMSVLQVPPE 1180
                 +   +   P +++  E+         K +      +SSPD S E           
Sbjct: 1227 ARGGSKKAPAKAKPIAVEDEEEEEDDEVLALKDRLAAYNLNSSPDHSAE----------- 1275

Query: 1181 DNTRRNSADNLNAPIIEISDTEVDCENKQQTAETVIEISDSEVVCEDEVPNTRINNPSGD 1360
                   A    AP  +          K++T  ++ ++S+     EDE+        S D
Sbjct: 1276 -------AMETEAPKAQKKAPTRKAAAKKKTLPSIADVSEG----EDEI------EISDD 1318

Query: 1361 EKLEDQIASTVESGMTSVDKTSQENKNRHVMITRKRANMSRQNGATSLANGSSGSVLKAV 1540
            ++ E ++A   +        T++          +KR   ++Q  A  +      S+LK  
Sbjct: 1319 DESEPEVAVGGKKKGGRKPATAKAAPAAAKQPPKKRGPANKQ--AVGIGQKLITSILKPA 1376

Query: 1541 ENI-MVSPEKKLRRTSSFPFRKKKNYSPTKN 1630
            EN    SPEKK+R+  + PF +K      KN
Sbjct: 1377 ENTDNSSPEKKVRKMRASPFNEKSGAVLGKN 1407


>ref|XP_006439079.1| hypothetical protein CICLE_v10030505mg [Citrus clementina]
            gi|557541275|gb|ESR52319.1| hypothetical protein
            CICLE_v10030505mg [Citrus clementina]
          Length = 1456

 Score =  321 bits (822), Expect = 9e-85
 Identities = 214/569 (37%), Positives = 306/569 (53%), Gaps = 34/569 (5%)
 Frame = +2

Query: 2    MIPWYKGFKGTIESTNTKDAGKSYVVKGIIEEVNKTTVRITELPVRKSTEEYKQFLDKLI 181
            M PWY+GF+GTIE T +K+AG +Y V GIIEEVN+TT+RI ELP+R+ T++Y++FL+ +I
Sbjct: 867  MHPWYRGFRGTIEKTASKEAGVTYTVTGIIEEVNETTLRIKELPIRRWTQDYREFLESII 926

Query: 182  SKGGRNKEQFIKDFREFNDDKTVHFEIYMSEKNLAMAKEEGLIEKFKLSTTISTSNMHLF 361
             +     + FI+ FR+++DD TV FE+++SE+++   K+EGL++KFKL+TTISTSNMHLF
Sbjct: 927  DQN----DSFIRGFRQYSDDTTVDFEVFLSEESMMRTKQEGLLKKFKLTTTISTSNMHLF 982

Query: 362  NPKRVLAKYSSPEKIIEEFCDLRLEFYEKRKIFMLSMXXXXXXXXXNKVRFIDEVIQGKI 541
            + K V+ KY +PE+I+EEF  +RLEFYEKRK   L           NKVRFI  V+ G+I
Sbjct: 983  DSKGVIKKYDTPEQILEEFFHIRLEFYEKRKKVQLENLELELLKLENKVRFILGVVNGEI 1042

Query: 542  ILMNRKRSDLLDELKQKNFTPFPRNA------------------XXXXXXXXXXXXXYEY 667
            ++ NRKR+DLL EL+QK FTPFP+N+                               Y+Y
Sbjct: 1043 VVNNRKRTDLLLELRQKGFTPFPKNSKSIEAVVAGATDETEESEENPEVVNGVQSIDYDY 1102

Query: 668  LLSMPIGTLTMEKVQELCAQRKKLNVEVDGLRHATPKSLWLKDLDSLEQKLN-LQSKIYD 844
            LLSM IGTLT+EKVQ L A R KLN EVD LR ATP+SLW+KDLD+L+ +L+ L      
Sbjct: 1103 LLSMAIGTLTLEKVQGLLADRDKLNEEVDDLRKATPESLWVKDLDALDMQLDELDKSDAR 1162

Query: 845  MPEKRLEV--NAEISKRPK---RTMRKKQESSEKKANN---KDGLAEKHTV-----PSDC 985
              E+R+++  N      PK   +   K    ++KK+NN    + + E   V     P   
Sbjct: 1163 AEEERMKIKGNGNSDAGPKIVAKRAPKNARKNDKKSNNARATEAMGEMDNVTKVVKPKGR 1222

Query: 986  TG-KVPEAVELEGITTGRDEISTPNPPSLDVNEDRGPKQKEEQPKQSSSPDTSREPKMSV 1162
             G K   A +L+      DE+         +NE     + E  P QS   +T +      
Sbjct: 1223 AGLKKAPAEKLD--DEEEDEVPDLKQRLAKLNEQLASTKLEPSPDQSGVMETEK------ 1274

Query: 1163 LQVP-PEDNTRRNSADNLNAPIIEISDTEVDCENKQQTAETVIEISDSEVVCEDEVPNTR 1339
            +QVP  +    + +A    A  +E SD+E                 D  ++ +DE     
Sbjct: 1275 VQVPAKKKEPSKRTAAQKKAVTVETSDSE-----------------DEIIIDDDEA--FE 1315

Query: 1340 INNPSGDEKLEDQIASTVESGMTSVDKTSQENKNRHVMITRKRANMSRQNGATSLANGSS 1519
            I  P   +K   + A   ++   +V+             T+KR    +Q    SL     
Sbjct: 1316 IAAPEAGKKGGRKAAGNTKAAKPAVE-------------TKKRGPAKKQQPEASLGQRLL 1362

Query: 1520 GSVLKAVENIMVSPEKKLRRTSSFPFRKK 1606
              +LK  E+   SPEKK+R+  + PF KK
Sbjct: 1363 TEMLKPTES---SPEKKVRKMRASPFNKK 1388


>ref|XP_006482851.1| PREDICTED: DNA topoisomerase 2-like [Citrus sinensis]
          Length = 1456

 Score =  320 bits (821), Expect = 1e-84
 Identities = 216/569 (37%), Positives = 305/569 (53%), Gaps = 34/569 (5%)
 Frame = +2

Query: 2    MIPWYKGFKGTIESTNTKDAGKSYVVKGIIEEVNKTTVRITELPVRKSTEEYKQFLDKLI 181
            M PWY+GF+GTIE T +K+AG +Y V GIIEEVN+TT+RI ELP+R+ T++Y++FL+ +I
Sbjct: 867  MHPWYRGFRGTIEKTASKEAGVTYTVTGIIEEVNETTLRIKELPIRRWTQDYREFLESII 926

Query: 182  SKGGRNKEQFIKDFREFNDDKTVHFEIYMSEKNLAMAKEEGLIEKFKLSTTISTSNMHLF 361
             +     + FI+ FR+++DD TV FE+++SE+++   K+EGL++KFKL+TTISTSNMHLF
Sbjct: 927  DQN----DSFIRGFRQYSDDTTVDFEVFLSEESMMRTKQEGLLKKFKLTTTISTSNMHLF 982

Query: 362  NPKRVLAKYSSPEKIIEEFCDLRLEFYEKRKIFMLSMXXXXXXXXXNKVRFIDEVIQGKI 541
            + K V+ KY +PE+I+EEF  +RLEFYEKRK   L           NKVRFI  V+ G+I
Sbjct: 983  DSKGVIKKYDTPEQILEEFFHIRLEFYEKRKKVQLENLELELLKLENKVRFILGVVNGEI 1042

Query: 542  ILMNRKRSDLLDELKQKNFTPFPRNA------------------XXXXXXXXXXXXXYEY 667
            ++ NRKR+DLL EL+QK FTPFP+N+                               Y+Y
Sbjct: 1043 VVNNRKRTDLLLELRQKGFTPFPKNSKSIEAVVAGATDETEESEENPEVVNGVQSIDYDY 1102

Query: 668  LLSMPIGTLTMEKVQELCAQRKKLNVEVDGLRHATPKSLWLKDLDSLEQKLN-LQSKIYD 844
            LLSM IGTLT+EKVQ L A R KLN EVD LR ATP+SLW+KDLD+L+ +L+ L      
Sbjct: 1103 LLSMAIGTLTLEKVQGLLADRDKLNEEVDDLRKATPESLWVKDLDALDMQLDELDKSDAR 1162

Query: 845  MPEKRLEV--NAEISKRPK---RTMRKKQESSEKKANN---KDGLAEKHTV-----PSDC 985
              E+R+++  N      PK   +   K    ++KK+NN    + + E   V     P   
Sbjct: 1163 AEEERMKIKGNGNSDAGPKIVAKRAPKNARKNDKKSNNARATEAMGEMDNVTKVVKPKGR 1222

Query: 986  TG-KVPEAVELEGITTGRDEISTPNPPSLDVNEDRGPKQKEEQPKQSSSPDTSREPKMSV 1162
             G K   A +L+      DE+         +NE     + E  P QS   +T +      
Sbjct: 1223 AGLKKAPAEKLD--DEEEDEVPDLKQRLAKLNEQLASTKLEPSPDQSGVMETEK------ 1274

Query: 1163 LQVP-PEDNTRRNSADNLNAPIIEISDTEVDCENKQQTAETVIEISDSEVVCEDEVPNTR 1339
            +QVP  +    + +A    A  +E SD+E                 D  ++ +DE     
Sbjct: 1275 VQVPAKKKEPSKRTAAQKKAVTVETSDSE-----------------DEIIIDDDEA--FE 1315

Query: 1340 INNPSGDEKLEDQIASTVESGMTSVDKTSQENKNRHVMITRKRANMSRQNGATSLANGSS 1519
            I  P   +K          +G T   K + E        T+KR    +Q    SL     
Sbjct: 1316 IAAPEAGKK-----GGRKAAGNTKAAKPAAE--------TKKRGPAKKQQPEASLGQRLL 1362

Query: 1520 GSVLKAVENIMVSPEKKLRRTSSFPFRKK 1606
              +LK  E+   SPEKK+R+  + PF KK
Sbjct: 1363 TEMLKPTES---SPEKKVRKMRASPFNKK 1388


>ref|XP_004229644.1| PREDICTED: DNA topoisomerase 2-like [Solanum lycopersicum]
          Length = 1477

 Score =  320 bits (819), Expect = 2e-84
 Identities = 219/574 (38%), Positives = 299/574 (52%), Gaps = 31/574 (5%)
 Frame = +2

Query: 2    MIPWYKGFKGTIESTNTKDAGKSYVVKGIIEEVNKTTVRITELPVRKSTEEYKQFLDKLI 181
            M PWYKGFKG IE T TK+ G +Y V GIIEEV++TT+RI+ELPVR+ TE+YKQFL+ + 
Sbjct: 868  MDPWYKGFKGKIEKTATKETGATYTVTGIIEEVSETTLRISELPVRRWTEDYKQFLESMT 927

Query: 182  SKGGRNKEQFIKDFREFNDDKTVHFEIYMSEKNLAMAKEEGLIEKFKLSTTISTSNMHLF 361
                + K+ FIK+ R + D+ +V FE+ MSE NL +A++EGL++KFKL+TTISTSNMHLF
Sbjct: 928  VSTDKAKDSFIKEVRAYGDENSVCFEVIMSEDNLLLAQQEGLLKKFKLTTTISTSNMHLF 987

Query: 362  NPKRVLAKYSSPEKIIEEFCDLRLEFYEKRKIFMLSMXXXXXXXXXNKVRFIDEVIQGKI 541
            + K  + KY +PE+I+EEF  +RLE+YEKRK  +L +         NKV+FI  V++G+I
Sbjct: 988  DSKGKIKKYDAPEEILEEFYHVRLEYYEKRKKALLEILELELLRIENKVKFILGVVKGEI 1047

Query: 542  ILMNRKRSDLLDELKQKNFTPFPR------------------NAXXXXXXXXXXXXXYEY 667
            I+ NRKR++LL ELK K FTPFP+                                 Y+Y
Sbjct: 1048 IVNNRKRAELLLELKNKGFTPFPKKKPVEAVVADSTDDADDSEESPEESSRGVRASDYDY 1107

Query: 668  LLSMPIGTLTMEKVQELCAQRKKLNVEVDGLRHATPKSLWLKDLDSLEQKLNLQSKIYDM 847
            LLSM IGTLT+EKVQELCA R KLN EV+ +R+ATPK LW+KDLD L+++L+ Q KI   
Sbjct: 1108 LLSMAIGTLTLEKVQELCADRDKLNAEVEDMRNATPKHLWMKDLDVLDKQLDEQDKIDIQ 1167

Query: 848  PE------KRLEVNAEISKRPKRTMRKKQESSEKKANNKD----GLAEKHTVPSDCTGKV 997
             E      K+  +NA     PK   RK  + +E  A + D      AE        T  V
Sbjct: 1168 TEEAREKLKKKVMNAAGKAAPKPKPRKTNKKAESTAESMDVSFGSTAE--------TANV 1219

Query: 998  PEAVELEGITTGRDEISTPNPPSLDVNEDR--GPKQKEEQPKQSSSPDTSREPKMSVLQV 1171
             E V+ +G   GR   + P     +  ED     K +      +SSPD S   +  V + 
Sbjct: 1220 SEVVKPKG--RGRPAKAKPIVVEDEEEEDEVLALKDRLAAYNLNSSPDRSEVTETEVPKA 1277

Query: 1172 PPEDNTRRNSADNLNAPII-EISDTEVDCENKQQTAETVIEISDSEVVCEDEVPNTRINN 1348
              +   +R +A     P   ++SD            E  IEI D E      V   +   
Sbjct: 1278 QTKAPAKRAAAQKKALPSTPDVSD-----------GEDAIEIDDDEFEPAAAVGGKK--- 1323

Query: 1349 PSGDEKLEDQIASTVESGMTSVDKTSQENKNRHVMITRKRANMSRQNGATSLANGSSGSV 1528
              G  K     A+   +      K +  N                 N + S+       V
Sbjct: 1324 -KGGRK---PAAAKAAAAPKPPGKKAPAN-----------------NQSQSVGQRLITQV 1362

Query: 1529 LKAVENIMVSPEKKLRRTSSFPFRKKKNYSPTKN 1630
            LK  E+  VSP++K+R+  + PF KK      KN
Sbjct: 1363 LKPAEDAGVSPDRKVRKMRASPFNKKSGAVMGKN 1396


>gb|EMJ21781.1| hypothetical protein PRUPE_ppa000202mg [Prunus persica]
          Length = 1471

 Score =  312 bits (800), Expect = 3e-82
 Identities = 209/565 (36%), Positives = 293/565 (51%), Gaps = 28/565 (4%)
 Frame = +2

Query: 2    MIPWYKGFKGTIESTNTKDAGKSYVVKGIIEEVNKTTVRITELPVRKSTEEYKQFLDKLI 181
            M PWY+GF GTIE T  K++G SY V G+IEE N+TTVRI+ELP+R+ T++YK+FL+ + 
Sbjct: 874  MDPWYRGFSGTIEKT-VKESGVSYTVCGVIEEGNETTVRISELPIRRWTQDYKEFLESIS 932

Query: 182  SKGGRNKEQFIKDFREFNDDKTVHFEIYMSEKNLAMAKEEGLIEKFKLSTTISTSNMHLF 361
                + K+ FI+ F + +D  TV   +++ E+NL  A++EGL++KFKL+T+ISTSNMHLF
Sbjct: 933  QGNDKAKDPFIEGFTQHSDHSTVDIIVHLPEENLMAARQEGLLKKFKLTTSISTSNMHLF 992

Query: 362  NPKRVLAKYSSPEKIIEEFCDLRLEFYEKRKIFMLSMXXXXXXXXXNKVRFIDEVIQGKI 541
            +PK V+ KY +PE+I+EEF  LRLEFYEKRK  +L           NKVRFI  V+ G+I
Sbjct: 993  DPKGVIKKYDTPEQILEEFFHLRLEFYEKRKKVLLDNLEMELLKLENKVRFILAVVNGEI 1052

Query: 542  ILMNRKRSDLLDELKQKNFTPFPRNA--------------------XXXXXXXXXXXXXY 661
            I+ NR+R+DL  EL+QK FTPFP+                                   Y
Sbjct: 1053 IVSNRRRADLFLELQQKGFTPFPKKTKAQEPEVAGAIEDTEETEENSESASGNGARISDY 1112

Query: 662  EYLLSMPIGTLTMEKVQELCAQRKKLNVEVDGLRHATPKSLWLKDLDSLEQKLNLQSKIY 841
            EYL+SM IGTLT+E+VQ LCA R K+N EV  LR++TP+SLWLKDLD+LE +L    K  
Sbjct: 1113 EYLISMAIGTLTIERVQALCADRDKVNNEVAELRNSTPRSLWLKDLDALEMELGELEKSE 1172

Query: 842  DMPEK-----RLEVNAEISKRPKRTMRKKQESSEKKANNKDGLAEKHTVPSDCTGKVPEA 1006
             + E+     R +V    + +  R   K    + KKANN +  AE     S    ++ +A
Sbjct: 1173 ALAEEAKKKSRNQVKNAPAAKVSRPAPKNPRKNNKKANNAEAAAESRETSSSFVFEMEKA 1232

Query: 1007 VELEGITTGRDEISTPNPPSLDVNEDRGPKQKEEQPKQSSSPDTSREPKMSVLQVPPEDN 1186
             E+     G      P           G KQ +     S   D   E K   L     D+
Sbjct: 1233 PEIVKRKVGAVAKKAP----------AGKKQAKSAVVLSDDDDEVLELK-DRLAAYNLDS 1281

Query: 1187 TRRNSADNLNAPIIEISDTEVDCENKQQTAETVIEISDSEVVCEDEVPNTRINNPSGDEK 1366
            +  NSA           +TEV  E  Q+                 + P+ R      DE 
Sbjct: 1282 SPENSAG---------KETEVPQEPVQR-----------------KEPSKRAMQIDDDED 1315

Query: 1367 LEDQIASTVESGMTSVDKTSQENK-NRHVMITRKRANMSRQNGATSLANGSS--GSVLKA 1537
             E +IA+   +G     K +   K ++     +KR   + +    S ++G      +LK 
Sbjct: 1316 FEVEIAAAPAAGKKGGRKAAGTTKASKPPAAAKKRGAAANKQSQASSSSGQKLLTDMLKP 1375

Query: 1538 VENIMVSPEKKLRRTSSFPFRKKKN 1612
            VE   VSPE K+R+  + PF KK +
Sbjct: 1376 VETSGVSPEPKVRKMRASPFNKKSS 1400


>gb|EOY18139.1| Topoisomerase II isoform 3 [Theobroma cacao]
          Length = 1244

 Score =  310 bits (795), Expect = 1e-81
 Identities = 172/364 (47%), Positives = 232/364 (63%), Gaps = 24/364 (6%)
 Frame = +2

Query: 2    MIPWYKGFKGTIESTNTKDAGKSYVVKGIIEEVNKTTVRITELPVRKSTEEYKQFLDKLI 181
            M PWY+GFKG IE T +K+AG +Y + GIIEEV++TT+RITELPVR+ T++Y++FL+ +I
Sbjct: 868  MHPWYRGFKGNIEKTASKEAGVTYTITGIIEEVDETTLRITELPVRRWTQDYREFLESII 927

Query: 182  SKGGRNKEQFIKDFREFNDDKTVHFEIYMSEKNLAMAKEEGLIEKFKLSTTISTSNMHLF 361
            +      + FIK+FR+++DD TV FE+ ++E+N+ +AK+EGL++KFKL+TTISTSNMHLF
Sbjct: 928  T----GNDPFIKEFRQYSDDTTVEFEVILTEENMMVAKQEGLLKKFKLTTTISTSNMHLF 983

Query: 362  NPKRVLAKYSSPEKIIEEFCDLRLEFYEKRKIFMLSMXXXXXXXXXNKVRFIDEVIQGKI 541
            + K ++ KY +PE+I+EEF  LR EFYEKRK  +L           NKVRFI  V++G+I
Sbjct: 984  DSKGMIKKYDTPEQILEEFFHLRFEFYEKRKKLLLDNLEMELLKMENKVRFILGVVKGEI 1043

Query: 542  ILMNRKRSDLLDELKQKNFTPFPRNA-------------------XXXXXXXXXXXXXYE 664
            I+ NRKR+DL  EL+ K FTPFP+ A                                Y+
Sbjct: 1044 IVNNRKRADLFLELQTKGFTPFPKKAKTVEVAVAGATDDTEETEENSEVSAKGLQASDYD 1103

Query: 665  YLLSMPIGTLTMEKVQELCAQRKKLNVEVDGLRHATPKSLWLKDLDSLEQKLNLQSKIYD 844
            YLLSM IG+LT+EKVQELCA R KL  EV+ LR ATPKSLWLKDLD+LE +L+ Q K   
Sbjct: 1104 YLLSMAIGSLTLEKVQELCADRDKLQQEVEDLRKATPKSLWLKDLDNLEIQLDEQDKAAQ 1163

Query: 845  MPE--KRLEVNAEISKRPKRTMRKKQESSEKKANNKDGLAEKHTVPSDC---TGKVPEAV 1009
              E  K ++   E  KR +R   K      KK  N + + E   + S     T   P AV
Sbjct: 1164 AEEAAKLVKGRGEAGKRAQRQAPKIPRKINKKEKNAETVTETTDISSSSAMETETAPAAV 1223

Query: 1010 ELEG 1021
            + +G
Sbjct: 1224 KPKG 1227


>ref|XP_002314046.2| DNA topoisomerase family protein [Populus trichocarpa]
            gi|550331162|gb|EEE88001.2| DNA topoisomerase family
            protein [Populus trichocarpa]
          Length = 1482

 Score =  309 bits (792), Expect = 3e-81
 Identities = 209/577 (36%), Positives = 301/577 (52%), Gaps = 42/577 (7%)
 Frame = +2

Query: 2    MIPWYKGFKGTIESTNTKDAG-KSYVVKGIIEEVNKTTVRITELPVRKSTEEYKQFLDKL 178
            M PWY+GFKGTIE   +K+ G  SY V G+I EVN+TT+RITELP+R+ T++YK FL+ +
Sbjct: 871  MNPWYRGFKGTIEKGASKEGGCSSYTVNGVINEVNETTLRITELPIRRWTDDYKAFLNSV 930

Query: 179  IS-----KGGRNKEQFIKDFREFNDDKTVHFEIYMSEKNLAMAKEEGLIEKFKLSTTIST 343
                    G   K+ F+KDFR++ DD  VHFE+ +SE+N+ +AK+EGL++KFKL+TTIST
Sbjct: 931  TEGTRDENGNLPKDPFVKDFRKYGDDAAVHFEVQLSEENMLVAKQEGLLKKFKLTTTIST 990

Query: 344  SNMHLFNPKRVLAKYSSPEKIIEEFCDLRLEFYEKRKIFMLSMXXXXXXXXXNKVRFIDE 523
            SNMHLF+   V+ KY +PE+I+E F  LRLE+YE RK  +L           NKVRFI  
Sbjct: 991  SNMHLFDSAGVIKKYDNPEQILENFFHLRLEYYETRKKVLLENLEFELLKLENKVRFILG 1050

Query: 524  VIQGKIILMNRKRSDLLDELKQKNFTPFPR--------------NAXXXXXXXXXXXXXY 661
            V++G+II+ NRKR+DLL EL QK F   P+               A             Y
Sbjct: 1051 VVRGEIIVNNRKRADLLLELHQKGFNAIPKKSKAVVAGATDDTEEAEDSPDVSGVRASDY 1110

Query: 662  EYLLSMPIGTLTMEKVQELCAQRKKLNVEVDGLRHATPKSLWLKDLDSLEQKLNLQSKIY 841
            +YLLSM IGTLT+E+VQ+LCA R KLN EVD LR  TPK LW+KDL++LE +L++  + Y
Sbjct: 1111 DYLLSMAIGTLTLERVQQLCADRDKLNGEVDSLRKTTPKVLWVKDLEALEMQLDMLDE-Y 1169

Query: 842  DMP---------------EKRLEVNAEISKRPKRTMRK--KQESSEKKANNKDGLAEKHT 970
            D                 E   +V+ +  K P++  +K   +E S +        A + T
Sbjct: 1170 DAEAEEARRKLKGGGAKGEAGFKVSKQAPKYPRKNTKKAINEEVSVETTGTSSSFAIE-T 1228

Query: 971  VPSDCTGKVPEAVELEGITTGRDEISTPNPPSLDVNED---RGPKQKEEQPKQSSSPDTS 1141
              S+    V +     G      ++   +P   D +ED      K +    +  SSP+ S
Sbjct: 1229 ASSENAAAVVKPKGRAGSKKAPAKMEKLSPVLDDFDEDDEIESLKDRLNAYRLDSSPEQS 1288

Query: 1142 REPKMSVLQVPPEDNTRRNSADNLNAPIIEISDTEVDCENKQQTAETVIEISDSEVVCED 1321
             + +  VLQVP     RR +A                   +++    V  ISDSE     
Sbjct: 1289 ADMETDVLQVP----ARRGAA-------------------RKKPLANVSVISDSE----- 1320

Query: 1322 EVPNTRINNPSGDEKLEDQIASTVESGMTSVDKTSQENKN--RHVMITRKRANMSRQNGA 1495
                   + P+ D+  + ++ +  E+      K +  N    +    T++R   S+Q  +
Sbjct: 1321 -------DEPNLDDDADVEVKALPETKKKGGRKAAAANDKAAKPPAATKRRGPASQQ--S 1371

Query: 1496 TSLANGSSGSVLKAVENIMVSPEKKLRRTSSFPFRKK 1606
              L       +LK  E   +SPEKK+R+  + PF KK
Sbjct: 1372 QGLGQKLLTEMLKPAEGAGISPEKKVRKVRASPFNKK 1408


>gb|EXB68160.1| DNA topoisomerase 2 [Morus notabilis]
          Length = 1451

 Score =  303 bits (775), Expect = 2e-79
 Identities = 208/571 (36%), Positives = 299/571 (52%), Gaps = 36/571 (6%)
 Frame = +2

Query: 2    MIPWYKGFKGTIESTNTKDAGKSYVVKGIIEEVNKTTVRITELPVRKSTEEYKQFLDKLI 181
            MIPWY+GFKGTIE ++ K+A  S+ V G++EEVN+TTVRITELP+R+ T++YK+FLD + 
Sbjct: 836  MIPWYRGFKGTIEKSS-KEA--SFFVSGLMEEVNETTVRITELPIRRWTQDYKEFLDSIC 892

Query: 182  SKGGRNKEQFIKDFREFNDDKTVHFEIYMSEKNLAMAKEEGLIEKFKLSTTISTSNMHLF 361
                + K+ FI+DF + +D  TV   ++++E+ L   K+EGL++K KL+T+IST+NMHLF
Sbjct: 893  YGNDKAKDPFIEDFTQHSDHSTVDILVHLAEETLIAVKQEGLLKKLKLTTSISTANMHLF 952

Query: 362  NPKRVLAKYSSPEKIIEEFCDLRLEFYEKRKIFMLSMXXXXXXXXXNKVRFIDEVIQGKI 541
            +   V+ KY +PE+I+EEF  LRLEFYEKRK  +L           NKVRFI  V+ G+I
Sbjct: 953  DANGVIKKYDTPEQILEEFYHLRLEFYEKRKKALLDNLELELLKLANKVRFILGVVTGEI 1012

Query: 542  ILMNRKRSDLLDELKQKNFTPFPR---------------------NAXXXXXXXXXXXXX 658
            ++ NRKR+DL  EL++K FTPFP+                     N+             
Sbjct: 1013 VVSNRKRADLFVELQRKGFTPFPKKTKAVEPEVAGVTEDAEDTEENSNAEAISTEARISD 1072

Query: 659  YEYLLSMPIGTLTMEKVQELCAQRKKLNVEVDGLRHATPKSLWLKDLDSLEQKLNLQSKI 838
            YEYLLSM IGTLT+EKVQ LC ++ KLN EV+ LR ATPKSLW+KDLD+LE +L+  +K 
Sbjct: 1073 YEYLLSMAIGTLTLEKVQALCGEKDKLNNEVEELRKATPKSLWVKDLDALETQLDELNKS 1132

Query: 839  YDMPE------KRLEVNAEISKRPKRTMRKKQESSEKKANNKDGLAE--KHTVPSDCTGK 994
                E      K    NA +SK   R   K    + KKA+N + +A+  ++   +    K
Sbjct: 1133 DAQAEEARKKSKGQVKNAAVSK-VSRQAPKVPRKNTKKASNAEAIADITENFDSAMEFEK 1191

Query: 995  VPEAVELEGITTGRDEISTPNPPSLDVNEDR--GPKQKEEQPKQSSSPDTSREPKMSVLQ 1168
             PE  + +G    +   S       D ++D     K +       SSPD S E      Q
Sbjct: 1192 APEVAKPKGRAGPKKAASKVVVEDDDDDDDEVLALKDRLAAYNLDSSPDKSSEMDTEAPQ 1251

Query: 1169 VPPEDNTRRNSADNLNAPIIEISDTEVDCENKQQTAETVIEISDSEVVCEDEVPNTRINN 1348
            VP         A      +  +S+T              + + D +   +DE+       
Sbjct: 1252 VPVPKKAPTKRAAAQKKTLATVSET--------------VNLDDDD---DDEI------- 1287

Query: 1349 PSGDEKLEDQI-----ASTVESGMTSVDKTSQENKNRHVMITRKRANMSRQNGATSLANG 1513
              GDE  E +      A+  + G      T   +K      T++R   +++     L   
Sbjct: 1288 -DGDEDFELESTAPAKAAAKKGGKKPAVSTKAVSKAPAAAATKRRGAANKE--PQVLGQK 1344

Query: 1514 SSGSVLKAVENIMVSPEKKLRRTSSFPFRKK 1606
                +LK  EN  +SPEKK+R+  + PF KK
Sbjct: 1345 LLTDMLKPAENSGLSPEKKVRKMRASPFNKK 1375


>ref|XP_004308680.1| PREDICTED: DNA topoisomerase 2-like [Fragaria vesca subsp. vesca]
          Length = 1469

 Score =  291 bits (745), Expect = 7e-76
 Identities = 199/570 (34%), Positives = 292/570 (51%), Gaps = 35/570 (6%)
 Frame = +2

Query: 2    MIPWYKGFKGTIESTNTKDAGKSYVVKGIIEEVNKTTVRITELPVRKSTEEYKQFLDKLI 181
            M PWY+GF G IE T  K+ G SY   GIIEEVN+TT+RI+ELP+R+ T++YK+FL+ + 
Sbjct: 871  MDPWYRGFTGFIEKT-VKETGTSYTACGIIEEVNETTLRISELPIRRWTQDYKEFLESIS 929

Query: 182  SKGGRNKEQFIKDFREFNDDKTVHFEIYMSEKNLAMAKEEGLIEKFKLSTTISTSNMHLF 361
                + K+ FI+ F + +D  TV   +++ E+NL  A++EGL++KF+L+T+I+T+NMHLF
Sbjct: 930  QGNDKAKDPFIEGFTQHSDHSTVEILVHLPEENLMAARKEGLLKKFRLTTSIATTNMHLF 989

Query: 362  NPKRVLAKYSSPEKIIEEFCDLRLEFYEKRKIFMLSMXXXXXXXXXNKVRFIDEVIQGKI 541
            +PK V+ KY + E+I+EEF  LRLEFYEKRK  +L           NKVRFI  V+ G+I
Sbjct: 990  DPKGVIKKYDTAEQILEEFFPLRLEFYEKRKKVLLDNLELELLKMENKVRFILGVVNGEI 1049

Query: 542  ILMNRKRSDLLDELKQKNFTPFPRNA--------------------XXXXXXXXXXXXXY 661
            I+ NRKR+DL  EL+QK FTPFP+                                   Y
Sbjct: 1050 IVSNRKRADLFLELQQKGFTPFPKKTKSVEPEVAGATEDTEETEENSETVISNGVRISDY 1109

Query: 662  EYLLSMPIGTLTMEKVQELCAQRKKLNVEVDGLRHATPKSLWLKDLDSLEQKLNLQSKIY 841
            EYL+SM IGTLT+E+V+ L A R K+N +V+ LR +TPKSLWLKDLD LE +LN   K  
Sbjct: 1110 EYLISMAIGTLTIERVEALLADRDKVNEQVNDLRGSTPKSLWLKDLDVLEAELNELEKSE 1169

Query: 842  DMPE--KRLEVNAEISKRPKRTMRK---KQESSEKKANNKDGLAEKHTVPSDCT---GKV 997
             + +  KR   N +I   P   + K   K   + KK NN + + E     S       K 
Sbjct: 1170 ALADEAKRKSRNNQIKNAPVGKVSKQAPKPRKNTKKVNNAEAIPESRETSSSSAMEIEKP 1229

Query: 998  PEAVELEGITTGRDEISTPNPPSLDVNEDRGPKQKEEQPKQSSSPDTSREPKMSVLQVPP 1177
            PE ++  G+  G                 + P +K+ +     S D   E  +       
Sbjct: 1230 PEVMKRRGVAAG---------------SKKAPAKKQVKSTVVLSDDDDDEEML------- 1267

Query: 1178 EDNTRRNSADNLNAPIIEISDTEVDCENKQQTAETVIEISDSEVVCEDEVPNTRINNPSG 1357
             D   R +A NL++      +TEV  +  Q+      E S    + +DE           
Sbjct: 1268 -DLKDRLAAYNLDSS--PDKETEVPLKPAQKK-----EASKKATLKDDE--------DDD 1311

Query: 1358 DEKLEDQI----ASTVESGMTSVDKTSQENKNRHVMITRKRANMSRQNGATSLANGS--- 1516
            D+  E +I    A+  + G             +  +  +KR   ++++  TS ++G    
Sbjct: 1312 DDDFEVEIAAAPAAVKKGGRKPAGAAKAAAAAKPPVAAKKRGAAAKKDTQTSSSSGQKLL 1371

Query: 1517 SGSVLKAVENIMVSPEKKLRRTSSFPFRKK 1606
            +  +  A E+  VSP+ K+R+    PF KK
Sbjct: 1372 TDMLKPAAESSGVSPDPKVRKMRESPFNKK 1401


>ref|XP_001758663.1| predicted protein [Physcomitrella patens] gi|162690273|gb|EDQ76641.1|
            predicted protein [Physcomitrella patens]
          Length = 1238

 Score =  291 bits (745), Expect = 7e-76
 Identities = 162/356 (45%), Positives = 218/356 (61%), Gaps = 23/356 (6%)
 Frame = +2

Query: 2    MIPWYKGFKGTIESTNTKDAGKSYVVKGIIEEVNKTTVRITELPVRKSTEEYKQFLDKLI 181
            M PWYK F GTIE + TKD G +Y + G IE++++TT++I ELPVRK T++YK+FLD L+
Sbjct: 872  MHPWYKSFMGTIECSATKDIGLTYTITGTIEQIDETTIKILELPVRKWTQDYKEFLDALM 931

Query: 182  SKGGRNKEQFIKDFREFNDDKTVHFEIYMSEKNLAMAKEEGLIEKFKLSTTISTSNMHLF 361
            +   +NKE FIKDFRE N D  VHFE+ +SE+N+A+A  EGL++KFKL+TTISTSNMHLF
Sbjct: 932  TPSDKNKEPFIKDFREHNTDTKVHFELTLSEENMAIALAEGLVKKFKLTTTISTSNMHLF 991

Query: 362  NPKRVLAKYSSPEKIIEEFCDLRLEFYEKRKIFMLSMXXXXXXXXXNKVRFIDEVIQGKI 541
            + K ++ KY +PE+I+EEF  +RL+ Y KRK   L           NKVRFI  V++G+I
Sbjct: 992  DAKGIIKKYDTPEQILEEFFHIRLDLYVKRKAVQLQNLQYELVKVDNKVRFILGVVKGEI 1051

Query: 542  ILMNRKRSDLLDELKQKNFTPFPRNAXXXXXXXXXXXXX-----------------YEYL 670
            I+ NRKR DLL EL+ K F PFP+ A                              Y+YL
Sbjct: 1052 IVNNRKRIDLLSELQHKGFAPFPKKAKSPDPPVVGADPLPEDNEQDEKVKGVKVADYDYL 1111

Query: 671  LSMPIGTLTMEKVQELCAQRKKLNVEVDGLRHATPKSLWLKDLDSLEQKLNLQSK----- 835
            LSMPIG+LT EKVQ+L  QR K+  EV+ L+ ATP++LW+KDLD    KL+ Q +     
Sbjct: 1112 LSMPIGSLTYEKVQQLRGQRDKMEEEVEELKRATPEALWIKDLDEFLVKLDAQEEQEAID 1171

Query: 836  -IYDMPEKRLEVNAEISKRPKRTMRKKQESSEKKANNKDGLAEKHTVPSDCTGKVP 1000
             +Y+      E N +  K+P    RK+     KK  + D   E +  P+     VP
Sbjct: 1172 AVYEAKHSAKEGN-QTFKKP--APRKQAAPKVKKVESVD---EDYDAPAAAAPVVP 1221


>ref|XP_001769043.1| predicted protein [Physcomitrella patens] gi|162679677|gb|EDQ66121.1|
            predicted protein [Physcomitrella patens]
          Length = 1172

 Score =  291 bits (744), Expect = 1e-75
 Identities = 147/294 (50%), Positives = 203/294 (69%), Gaps = 17/294 (5%)
 Frame = +2

Query: 2    MIPWYKGFKGTIESTNTKDAGKSYVVKGIIEEVNKTTVRITELPVRKSTEEYKQFLDKLI 181
            M PWYKGFKG+IE + TKD+G +Y + G I+++++TT++I+ELPVRK T++YK+FLD ++
Sbjct: 871  MHPWYKGFKGSIECSATKDSGFTYTITGAIDQIDETTIKISELPVRKWTQDYKEFLDVMM 930

Query: 182  SKGGRNKEQFIKDFREFNDDKTVHFEIYMSEKNLAMAKEEGLIEKFKLSTTISTSNMHLF 361
            +   +NKE FIKDFRE N D  VHFE+ +SE+N+A+A  EGL++KFKL+TTISTSNMHLF
Sbjct: 931  TPSDKNKEPFIKDFREHNTDTKVHFELSLSEENMAIALAEGLVKKFKLTTTISTSNMHLF 990

Query: 362  NPKRVLAKYSSPEKIIEEFCDLRLEFYEKRKIFMLSMXXXXXXXXXNKVRFIDEVIQGKI 541
            + K ++ KY +PE+I+EEF  +RL+ Y KRK   L           NKVRFI  V++G+I
Sbjct: 991  DNKGIIKKYDTPEQILEEFFHIRLDMYVKRKAVQLQNLEYELHKVDNKVRFILGVVKGEI 1050

Query: 542  ILMNRKRSDLLDELKQKNFTPFPRNAXXXXXXXXXXXXX-----------------YEYL 670
            I+ NRKR+DLL +L++K FTPFP+ +                              YEYL
Sbjct: 1051 IVNNRKRADLLADLQKKGFTPFPKKSKSSDPPVVGADPLPEDDEQDEKVKGIRAADYEYL 1110

Query: 671  LSMPIGTLTMEKVQELCAQRKKLNVEVDGLRHATPKSLWLKDLDSLEQKLNLQS 832
            LSMPIGTLT EKVQ+L  QR K+  EV+ L+ ATP++LW+KDLD    KL++ +
Sbjct: 1111 LSMPIGTLTFEKVQQLRGQRDKMEGEVEELKKATPEALWIKDLDEFLVKLDVSN 1164


>ref|XP_006838283.1| hypothetical protein AMTR_s00103p00101630 [Amborella trichopoda]
            gi|548840751|gb|ERN00852.1| hypothetical protein
            AMTR_s00103p00101630 [Amborella trichopoda]
          Length = 1505

 Score =  289 bits (740), Expect = 3e-75
 Identities = 192/574 (33%), Positives = 291/574 (50%), Gaps = 39/574 (6%)
 Frame = +2

Query: 2    MIPWYKGFKGTIESTNTKDAGKSYVVKGIIEEVNKTTVRITELPVRKSTEEYKQFLDKLI 181
            M PWYKGFKGTIE + TK+ G  Y V GI+EE+N+TT+RITELP+R+ TE+YK +L+ L 
Sbjct: 880  MEPWYKGFKGTIEKSATKEGGVGYTVSGIVEEINETTLRITELPIRRWTEDYKVYLESLR 939

Query: 182  SKGGRNKEQFIKDFREFNDDKTVHFEIYMSEKNLAMAKEEGLIEKFKLSTTISTSNMHLF 361
            +   + KE FI D++E N D  VHF++ + E+N+ ++++EGL++ FKL+TTISTSNMHLF
Sbjct: 940  TGSEKTKEPFIVDYKEHNTDTRVHFDVLLPEENMKISQQEGLMKMFKLTTTISTSNMHLF 999

Query: 362  NPKRVLAKYSSPEKIIEEFCDLRLEFYEKRKIFMLSMXXXXXXXXXNKVRFIDEVIQGKI 541
            N K V+ KY +PE+I+EEF  LRL++Y KRK  +L           NK RFI  V+ G+I
Sbjct: 1000 NAKGVIKKYDTPEQILEEFFHLRLDYYGKRKKVLLDNLELELLKLDNKARFILGVVNGEI 1059

Query: 542  ILMNRKRSDLLDELKQKNFTPFPRNA-------------------XXXXXXXXXXXXXYE 664
            ++  RKR+DL+ EL+ K FTPFP+ +                                Y+
Sbjct: 1060 VVSKRKRADLVLELRDKGFTPFPKKSKNVEAALAGATPVDEEGEESPEVDDRGINASDYD 1119

Query: 665  YLLSMPIGTLTMEKVQELCAQRKKLNVEVDGLRHATPKSLWLKDLDSLEQKLNLQSKIYD 844
            YLLSM IGTLT+EKVQELCA++ KL  +V  LR  TPK+LW+KDLD+   +L+ ++ + +
Sbjct: 1120 YLLSMAIGTLTIEKVQELCAEKDKLEHDVKELRGLTPKALWIKDLDAFLAQLDAEA-VQE 1178

Query: 845  MPEKRLEVNAEISKRPKRTMRKKQESSEKKANNKDGLAEKH--TVPSDCTGKVPEAVELE 1018
              +   E+N  +S   K     +Q     + N K     +H  T  SD T       E+ 
Sbjct: 1179 AKDDEYELNNMVSDAAKIF---RQVGKNPRKNTKKPAPAEHVDTDASDTT-----TTEVA 1230

Query: 1019 GITTGRDEISTPNPPSLDVNEDRGPKQKEEQPKQSS-SPDTSREPKMSVLQVPPEDNTRR 1195
                 R     P    +DV +       +   + +  + ++S E       +P      +
Sbjct: 1231 AKPKKRAPKKAPTKKKVDVEDMEDDLLLDLNARLAKYNIESSPEHADMETDLPERREPSK 1290

Query: 1196 NSADNLNAPIIEISDTEVDCENKQQTAETVIEISDSEVVCEDEVP--NTRINNPSGDEKL 1369
             +         +ISD E       +  E + E  + E   ED  P    +   P   EK 
Sbjct: 1291 RAVSKPQQVYADISDDE------SEHLEEIEEEKEEEQEDEDPKPAKGKKKQAPKPKEKK 1344

Query: 1370 EDQIASTVESGMTSVD------KTSQENKNRHVMITRKRANMSRQNGATSLANGSSGS-- 1525
            +   +S  E  ++  D      +T            +  +N  +     +   G++ S  
Sbjct: 1345 KMDGSSDEEFVISDEDLSVFDIETEDAPPKPKGRAKKPLSNKPKAPTGAAKKRGAASSKQ 1404

Query: 1526 -------VLKAVENIMVSPEKKLRRTSSFPFRKK 1606
                   + + ++ + VSPEKK+R+  + PF KK
Sbjct: 1405 PILNQKLITEVLKPVGVSPEKKVRKMRASPFNKK 1438