BLASTX 2.2.25 [Feb-01-2011]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= Rehmannia23_contig00006955
         (3437 letters)

Database: ./nr 
           37,332,560 sequences; 13,225,080,153 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

dbj|BAG31376.1| topoisomerase I [Camptotheca acuminata]              1141   0.0  
dbj|BAG31377.1| topoisomerase I [Catharanthus roseus]                1129   0.0  
dbj|BAK32960.1| topoisomerase I [Ophiorrhiza pseudofasciculata]      1122   0.0  
dbj|BAG31375.1| topoisomerase I [Ophiorrhiza japonica]               1119   0.0  
dbj|BAK32958.1| topoisomerase I [Ophiorrhiza pedunculata]            1115   0.0  
dbj|BAK32962.1| topoisomerase I [Ophiorrhiza trichocarpon var. g...  1112   0.0  
dbj|BAK32961.1| topoisomerase I [Ophiorrhiza ridleyana]              1099   0.0  
dbj|BAG31373.1| topoisomerase I [Ophiorrhiza pumila]                 1098   0.0  
dbj|BAK32956.1| topoisomerase I [Ophiorrhiza fucosa]                 1097   0.0  
dbj|BAG31374.1| topoisomerase I [Ophiorrhiza liukiuensis]            1096   0.0  
gb|EOY12189.1| DNA topoisomerase I alpha isoform 1 [Theobroma ca...  1087   0.0  
dbj|BAK32959.1| topoisomerase I [Ophiorrhiza plumbea]                1082   0.0  
dbj|BAK32963.1| topoisomerase I [Ophiorrhiza sp. 35]                 1082   0.0  
ref|XP_006364175.1| PREDICTED: LOW QUALITY PROTEIN: DNA topoisom...  1074   0.0  
dbj|BAK32957.1| topoisomerase I [Ophiorrhiza harrisiana]             1070   0.0  
gb|AAD08711.1| topoisomerase I [Nicotiana tabacum] gi|14626487|g...  1038   0.0  
ref|XP_004149585.1| PREDICTED: DNA topoisomerase 1-like [Cucumis...  1025   0.0  
ref|XP_006474977.1| PREDICTED: DNA topoisomerase 1-like isoform ...  1016   0.0  
ref|XP_006452479.1| hypothetical protein CICLE_v10007398mg [Citr...  1015   0.0  
ref|XP_002300344.1| DNA topoisomerase family protein [Populus tr...  1006   0.0  

>dbj|BAG31376.1| topoisomerase I [Camptotheca acuminata]
          Length = 894

 Score = 1141 bits (2952), Expect = 0.0
 Identities = 605/903 (66%), Positives = 680/903 (75%), Gaps = 10/903 (1%)
 Frame = -3

Query: 3162 MAVEACDKQKLXXXXXXXXEPLVFKRXXXXXXXXXXXSEAKKSLSQKHDRQLGRPAPDVR 2983
            MAV+AC K+K+        EPLVFKR           S+ KKS SQ++D Q GR   DV 
Sbjct: 1    MAVQACVKEKMMDEIDEDDEPLVFKRSNATSKHNQLNSDTKKS-SQRYDGQSGRQVSDVP 59

Query: 2982 SQNGQSTIVKKSKTVPLSKTPPVKYPLTSPKSSNTSGKALALKSPEVDSKPSTSVTDKSN 2803
            S NGQS+   K KT  LS    +K P+ SPK+S +  KA  + +P+V S  S+    K +
Sbjct: 60   STNGQSSSASKGKTTKLSS---MKSPIASPKASTSFAKASPVANPKVSS--SSDDRSKHS 114

Query: 2802 SVKHQIKDEKLSTEATGEPNEDSQDSEDDKPLSARLPAGLSKVNSNHAKKSPNTSTLSQK 2623
            S ++ I   K   E      E   DSED+KPLSARL  GL+K +SN+A K    S+ +  
Sbjct: 115  SKQNTINVVKEEKELVNPAAEPYGDSEDEKPLSARLFTGLTKGSSNNANKGLINSSPAS- 173

Query: 2622 RRIPIP--------EDSDDEIPLSSKFQVKSNAGESINRSSNSGERKPLLSKYDQNGSAS 2467
              +P+P        +DSDDEIPLSSKF++K+NAG S  +S  S + K L+S + QNGS +
Sbjct: 174  --LPVPKPEINRYSDDSDDEIPLSSKFRLKANAGTSTVKSYESDDNKTLVSNFQQNGSIN 231

Query: 2466 TERKPSTNLKKRPGDGVKTTDESYLKKPKLSEAATPHKNKEASIKAEMREED-DEDHVPI 2290
               K S  + KRP   VK++ +S +KKPKLS+A+TP  NK+AS KAE + +D D+DHVPI
Sbjct: 232  RGSKSSIKVNKRPLGEVKSSVQSSVKKPKLSDASTPVNNKQASKKAEPKADDSDDDHVPI 291

Query: 2289 SHRMXXXXXXXXXXXXXKN-ITKPIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSGEGQK 2113
            S RM             K  +TK +                             SGEG+K
Sbjct: 292  SQRMKKSATSGNKSSTAKQKVTKVVSSSMKKASKKFKKVVKKSKYSKSSKVPPSSGEGKK 351

Query: 2112 WTTLVHNGVIFPPPYKPHGVKMLYKGKPVDLTPEQEEVATMYAVMLETDYMNKPKFKENF 1933
            W TLVHNGVIFPPPYKPHGVKMLYKGKPVDLTPEQEEVATM+AVML+TDYM K KFKENF
Sbjct: 352  WNTLVHNGVIFPPPYKPHGVKMLYKGKPVDLTPEQEEVATMFAVMLDTDYMTKSKFKENF 411

Query: 1932 MADWRKILGKNHTIQSLEHCDFTPIYEWHXXXXXXXXXXXXXXXXXXXXXXXXXXXKYMW 1753
            M DWRKILGKNH IQ+LE CDFTPIYEWH                           KYMW
Sbjct: 412  MDDWRKILGKNHVIQNLEDCDFTPIYEWHQREKEKKKKMTAEEKKVLKEERLKQEEKYMW 471

Query: 1752 AIVNGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIRPSDITINIGKDAPIPECPIPGE 1573
            AIVNGVKEKVGNFRVEPP LFRGRGEHPKMGKLKK IRPSDITINIGKDAPIPECPIPGE
Sbjct: 472  AIVNGVKEKVGNFRVEPPSLFRGRGEHPKMGKLKKCIRPSDITINIGKDAPIPECPIPGE 531

Query: 1572 SWKEIRHDNTVTWLAYWNDPINPKEFKYVFLAASSTLKGQSDKEKYEKARLLKDYILGIR 1393
            SWKEIRHDNTVTWLA+WNDPI P+EFKYVFLAASS+LKGQSDKEKYEKARLLKD+I GIR
Sbjct: 532  SWKEIRHDNTVTWLAFWNDPIKPREFKYVFLAASSSLKGQSDKEKYEKARLLKDFIQGIR 591

Query: 1392 AAYTKDFTSKDPAKRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVEPVPPNT 1213
            AAYTKDF SKD  KRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVEP PP+ 
Sbjct: 592  AAYTKDFASKDITKRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVEPKPPSI 651

Query: 1212 LKFDFLGKDSIRYQNEVEVETAVFKAIQQFRSGKKGGDDLFDRLDTSKLNAHLKELMPGL 1033
            LKFDFLGKDSIRYQNEVEVE  V+KAIQQFR+GK+GGDDLFD+LDTSKLNAHLK LMPGL
Sbjct: 652  LKFDFLGKDSIRYQNEVEVELPVYKAIQQFRTGKRGGDDLFDKLDTSKLNAHLKGLMPGL 711

Query: 1032 TAKVFRTYNASITLDDMLSRETRGGDVAEKVVVYQHANKEVAIICNHQRTVSKSHSAQML 853
            TAKVFRTYNASITLD+MLSRET+GG+VAEK+VVYQHANKEVAIICNHQRTVSKSH AQM 
Sbjct: 712  TAKVFRTYNASITLDEMLSRETKGGNVAEKIVVYQHANKEVAIICNHQRTVSKSHPAQMT 771

Query: 852  RLNEKIEELKGVVEELQTDLARAKKGKPPLKSADGKPKRNLNPDALERKIAQTTAKIEKM 673
            RLN KI+ELKG+++ LQTDLARAKKGKPPL+ ADGKPKRNL P+ALERKI QT AKIEKM
Sbjct: 772  RLNGKIDELKGILDGLQTDLARAKKGKPPLEDADGKPKRNLTPEALERKIGQTNAKIEKM 831

Query: 672  ERDKETKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFAWAMDVDPG 493
            ERDKETKE LKT+ALGTSKI+YLDPRITVAWCKRHEVPIEK+FNKSLLAKFAW+MDVDP 
Sbjct: 832  ERDKETKEGLKTIALGTSKISYLDPRITVAWCKRHEVPIEKVFNKSLLAKFAWSMDVDPS 891

Query: 492  FRF 484
            FRF
Sbjct: 892  FRF 894


>dbj|BAG31377.1| topoisomerase I [Catharanthus roseus]
          Length = 910

 Score = 1129 bits (2921), Expect = 0.0
 Identities = 605/919 (65%), Positives = 667/919 (72%), Gaps = 26/919 (2%)
 Frame = -3

Query: 3162 MAVEACDKQKLXXXXXXXXEPLVFKRXXXXXXXXXXXSEAKKSLSQKHDRQLGRPAPDVR 2983
            MAVEAC    L        EP+VFKR           SE +K  SQK D Q  R   D R
Sbjct: 1    MAVEACPTPNLRDDMDEDDEPIVFKRNNSASKQSQTNSETRKVSSQKRDGQSVRQIYDSR 60

Query: 2982 SQNGQSTIVKKSKTVPLSK---------TPP-----VKYPLTSPKSSNTSGKALALKSPE 2845
              NG+S+  +K + VP SK         +PP     VK PL+SPK S +S K   + S  
Sbjct: 61   PANGESSSGQKGRMVPPSKPSQVKSPLSSPPSKPSQVKSPLSSPKVSTSSAKKSPVSSLP 120

Query: 2844 VDSKPSTSVTDKSNSVKHQ-----IKDEKLST-EATGEPNEDSQDSEDDKPLSARLPAGL 2683
             +SKPSTS + K            IK+EK S          DS+DS+D KPLS R  A  
Sbjct: 121  ANSKPSTSGSFKVKPFNQHKSATVIKEEKSSPLRLASAIINDSEDSDDGKPLSLRHSASS 180

Query: 2682 SKVNSNHAKKSPNTSTLSQKRRIPIPEDSDDEIPLSSKFQVKSNAGESINRSSNSGERKP 2503
            SK N+N   K  +          P  EDSDDE PLSS+F +KS  GES +++ +S + KP
Sbjct: 181  SKGNTNQVSKEGSK---------PENEDSDDEKPLSSRFPLKSGVGESTSKAYDSDDDKP 231

Query: 2502 LLSKYDQNGSASTERKP---STNLKKRPGDGVKTTDESYLKKPKLSEAATPHKNKEASIK 2332
            L  K   NGSA  + +P   S    KRP   +K++++  +KKPKLS    P   K+AS+K
Sbjct: 232  LAKKLQHNGSAMRDGQPNKYSNMSNKRPPGDIKSSNQLSVKKPKLSSVTAPTNKKQASVK 291

Query: 2331 AEMR-EEDDEDHVPISHRMXXXXXXXXXXXXXKNITKPIXXXXXXXXXXXXXXXXXXXXX 2155
             E + E+DD+DH+PIS R+             K  TK +                     
Sbjct: 292  PEPKAEDDDDDHLPISQRIKKSPTSESKSSSIKKTTKVVSSSVKKVNKKSKKVMKNSKYS 351

Query: 2154 XXXXXXXXSGEGQKWTTLVHNGVIFPPPYKPHGVKMLYKGKPVDLTPEQEEVATMYAVML 1975
                    SGEG+KW  L HNGVIFPPPYKPHG+KMLYKGKPVDLTPEQEEVATM+AVML
Sbjct: 352  KSSKVPPSSGEGKKWNKLEHNGVIFPPPYKPHGIKMLYKGKPVDLTPEQEEVATMFAVML 411

Query: 1974 ETDYMNKPKFKENFMADWRKILGKNHTIQSLEHCDFTPIYEWHXXXXXXXXXXXXXXXXX 1795
            +TDYMNKP+FKENF  DW+KILGKNH IQ+LE+CDF+PIYEWH                 
Sbjct: 412  DTDYMNKPRFKENFFGDWKKILGKNHVIQNLENCDFSPIYEWHQSEKEKKKQMTTEEKKA 471

Query: 1794 XXXXXXXXXXKYMWAIVNGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIRPSDITINI 1615
                      KYMWA V+G KEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIRP DITINI
Sbjct: 472  LKEEKLKQEEKYMWAWVDGKKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIRPCDITINI 531

Query: 1614 GKDAPIPECPIPGESWKEIRHDNTVTWLAYWNDPINPKEFKYVFLAASSTLKGQSDKEKY 1435
            GKDAPIPECP+PGE WKE+RHDNTVTWLA+WNDPINPKEFKYVFLAASSTLKG SDKEKY
Sbjct: 532  GKDAPIPECPVPGERWKEVRHDNTVTWLAFWNDPINPKEFKYVFLAASSTLKGLSDKEKY 591

Query: 1434 EKARLLKDYILGIRAAYTKDFTSKDPAKRQIAVATYLIDKLALRAGNEKDDDEADTVGCC 1255
            EKARLLKDYI GIRAAYTKDF SKDP K+QIAVATYLIDKLALRAGNEKDDDEADTVGCC
Sbjct: 592  EKARLLKDYIQGIRAAYTKDFASKDPTKKQIAVATYLIDKLALRAGNEKDDDEADTVGCC 651

Query: 1254 TLKVENVEPVPPNTLKFDFLGKDSIRYQNEVEVETAVFKAIQQFRSGKKGGDDLFDRLDT 1075
            TLKVENVEPVPPN LKFDFLGKDSIRYQNEVEVE AVFKAIQQFRSGK+G  DLFD LDT
Sbjct: 652  TLKVENVEPVPPNILKFDFLGKDSIRYQNEVEVEAAVFKAIQQFRSGKEGSSDLFDLLDT 711

Query: 1074 SKLNAHLKELMPGLTAKVFRTYNASITLDDMLSRETRGGDVAEKVVVYQHANKEVAIICN 895
            SKLNAHLKELMPGLTAKVFRTYNASITLDDMLSRET+GGDVAEKVVVYQHANKEVAIICN
Sbjct: 712  SKLNAHLKELMPGLTAKVFRTYNASITLDDMLSRETKGGDVAEKVVVYQHANKEVAIICN 771

Query: 894  HQRTVSKSHSAQMLRLNEKIEELKGVVEELQTDLARAKKGKPPLKS--ADGKPKRNLNPD 721
            HQRTVSKSHSAQMLRLNEKIEELK VVEEL++DL+R KKGKPPLKS  ADGKPKRNLNP+
Sbjct: 772  HQRTVSKSHSAQMLRLNEKIEELKAVVEELKSDLSRVKKGKPPLKSKNADGKPKRNLNPE 831

Query: 720  ALERKIAQTTAKIEKMERDKETKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFN 541
            +LE+KIAQT AKIEKMERDKETKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFN
Sbjct: 832  SLEKKIAQTNAKIEKMERDKETKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFN 891

Query: 540  KSLLAKFAWAMDVDPGFRF 484
            KSLLAKF WAMDVDP FRF
Sbjct: 892  KSLLAKFTWAMDVDPSFRF 910


>dbj|BAK32960.1| topoisomerase I [Ophiorrhiza pseudofasciculata]
          Length = 925

 Score = 1122 bits (2901), Expect = 0.0
 Identities = 598/926 (64%), Positives = 667/926 (72%), Gaps = 33/926 (3%)
 Frame = -3

Query: 3162 MAVEACDKQKLXXXXXXXXEPLVFKRXXXXXXXXXXXSEAKKSLSQKHDRQLGRPAPDVR 2983
            MAVEAC    L         P++FKR           SE KK   QK D Q      DVR
Sbjct: 1    MAVEACTTN-LMEDMEDDGGPVIFKRSKPAPKQNQANSEKKKLSLQKQDGQSAVHTSDVR 59

Query: 2982 SQNGQSTIVKKSKTVPLSKTPPVKYPLTSPKSSNTSGKALALKSPEVDSKPSTSVTDKSN 2803
              NG+S+  +K +  P +KTPPVK PL+SPK+SN+S KA  + SP  +SKPS S T  + 
Sbjct: 60   PANGESSSAQKGRIQPSAKTPPVKSPLSSPKASNSSAKASPITSPGANSKPSASATSTAK 119

Query: 2802 SVKHQIKD----EKLSTEATGEPNEDSQDSEDDKPLSARLPAGLSKVNSNHAKKSPNTST 2635
               H        E   +    + N +S+ S+D+KPLSAR     SK  SNHA K    S 
Sbjct: 120  QQNHHKSSAAFIEPKPSVPAAKANSNSESSDDEKPLSARTFGCSSKGKSNHANKEGGDSC 179

Query: 2634 LSQKRRIPIPEDSDDEIPLSSKFQVKSNAGESINRSSNSGERKPLLSKYDQNGSASTE-- 2461
              ++  I   EDS+DE PLS +F  KS+ GES ++S +S E+KPL +K  QNGSAS +  
Sbjct: 180  SIRRPVIEESEDSEDEKPLSCRFTSKSSLGESTSKSYDSDEKKPLAAKVQQNGSASRDGP 239

Query: 2460 -RKPSTNLKKRPGDGVKTTDESYLKKPKLSEAATPHKNKEASIKAEMREEDDE------- 2305
              K ++   KRP    K+ ++S +KKPKLS   T   NK+A++K E + EDD+       
Sbjct: 240  MNKSASLSNKRPPGEAKSLNQSSVKKPKLSSPITSISNKQAAVKPEPKAEDDDDNIPLSQ 299

Query: 2304 -----------------DHVPISHRMXXXXXXXXXXXXXKN-ITKPIXXXXXXXXXXXXX 2179
                             D+VPIS R+                 +  +             
Sbjct: 300  RGKKSQSATSKPKDDDDDNVPISQRIKKSPASVSKSSVPVKKASTVVSSSLKKVNKNSKK 359

Query: 2178 XXXXXXXXXXXXXXXXSGEGQKWTTLVHNGVIFPPPYKPHGVKMLYKGKPVDLTPEQEEV 1999
                            SGEGQKWTTLVHNGVIFPPPYKPHGVKMLYK +P+ LTPEQEEV
Sbjct: 360  VIKKTAYTKSSKVPPGSGEGQKWTTLVHNGVIFPPPYKPHGVKMLYKRQPITLTPEQEEV 419

Query: 1998 ATMYAVMLETDYMNKPKFKENFMADWRKILGKNHTIQSLEHCDFTPIYEWHXXXXXXXXX 1819
            ATM+AVML+TDYMNKP FKENF +DW+KILGKNH IQ+LE CDF PIYEWH         
Sbjct: 420  ATMFAVMLDTDYMNKPCFKENFFSDWKKILGKNHMIQNLEDCDFGPIYEWHQQEKEKKKQ 479

Query: 1818 XXXXXXXXXXXXXXXXXXKYMWAIVNGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIR 1639
                              KYMWAIV+GVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIR
Sbjct: 480  MTTEEKKALKEEKLQQEEKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIR 539

Query: 1638 PSDITINIGKDAPIPECPIPGESWKEIRHDNTVTWLAYWNDPINPKEFKYVFLAASSTLK 1459
            P DITINIGKDAPIPECPIPGE WKE+R+ NTVTWLAYWNDPIN KEFKYVFLAASSTLK
Sbjct: 540  PRDITINIGKDAPIPECPIPGERWKEVRNGNTVTWLAYWNDPINQKEFKYVFLAASSTLK 599

Query: 1458 GQSDKEKYEKARLLKDYILGIRAAYTKDFTS-KDPAKRQIAVATYLIDKLALRAGNEKDD 1282
            GQSDKEKYEKARLLKDYI GIRAAYTKDFT+ KDP K+QIAVATYLIDKLALRAGNEKDD
Sbjct: 600  GQSDKEKYEKARLLKDYIHGIRAAYTKDFTNNKDPMKKQIAVATYLIDKLALRAGNEKDD 659

Query: 1281 DEADTVGCCTLKVENVEPVPPNTLKFDFLGKDSIRYQNEVEVETAVFKAIQQFRSGKKGG 1102
            DEADTVGCCTLKVENVEPVPPN LKFDFLGKDSIRYQNEV+VE AVFKAIQQFRSGK+G 
Sbjct: 660  DEADTVGCCTLKVENVEPVPPNILKFDFLGKDSIRYQNEVQVEPAVFKAIQQFRSGKEGS 719

Query: 1101 DDLFDRLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSRETRGGDVAEKVVVYQHA 922
            +DLFDRLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLS+ET+GG+VAE VVVYQHA
Sbjct: 720  EDLFDRLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSKETKGGEVAENVVVYQHA 779

Query: 921  NKEVAIICNHQRTVSKSHSAQMLRLNEKIEELKGVVEELQTDLARAKKGKPPLKSADGKP 742
            NKEVAIICNHQRTVSKSHSAQM RLNEKI+ELK  +EEL+TDL+RAKKGKPP K ADGK 
Sbjct: 780  NKEVAIICNHQRTVSKSHSAQMSRLNEKIDELKTALEELKTDLSRAKKGKPPTKGADGKA 839

Query: 741  KRNLNPDALERKIAQTTAKIEKMERDKETKEDLKTVALGTSKINYLDPRITVAWCKRHEV 562
            KRNLNP+ALERKI QT AKIEKMERDKETKEDLKTVALGTSKINYLDPRITVAWCKRHEV
Sbjct: 840  KRNLNPEALERKITQTNAKIEKMERDKETKEDLKTVALGTSKINYLDPRITVAWCKRHEV 899

Query: 561  PIEKIFNKSLLAKFAWAMDVDPGFRF 484
            PIEKIFNKSLLAKFAW+MDVDP FRF
Sbjct: 900  PIEKIFNKSLLAKFAWSMDVDPSFRF 925


>dbj|BAG31375.1| topoisomerase I [Ophiorrhiza japonica]
          Length = 927

 Score = 1119 bits (2895), Expect = 0.0
 Identities = 594/928 (64%), Positives = 670/928 (72%), Gaps = 35/928 (3%)
 Frame = -3

Query: 3162 MAVEACDKQKLXXXXXXXXEPLVFKRXXXXXXXXXXXSEAKKSLSQKHDRQLGRPAPDVR 2983
            MAVEAC    L         P++FKR           SE KK   QKH  Q      DVR
Sbjct: 1    MAVEACTPN-LMEDMEDDEGPVIFKRSNPASKQNQANSEKKKLSLQKHVGQSAVHTSDVR 59

Query: 2982 SQNGQSTIVKKSKTVPLSKTPPVKYPLTSPKSSNTSGKALALKSPEVDSKPSTSVTDKSN 2803
              NG+S+  +K +  P +KTPPVK PL+SPK+SN+S KA  + SP  +SKPS S T  + 
Sbjct: 60   PANGESSSAQKGRIQPSAKTPPVKSPLSSPKASNSSAKASPITSPGANSKPSASATSTAK 119

Query: 2802 SVKHQIKD----EKLSTEATGEPNEDSQDSEDDKPLSARLPAGLSKVNSNHAKKSPNTST 2635
               H        E   +    + N +S+ S+D+KPLSAR     SK  SNHA K    S 
Sbjct: 120  QQNHHKSSAAFIEPKPSVPAAKANSNSESSDDEKPLSARTFGCSSKGKSNHANKEGGDSC 179

Query: 2634 LSQKRRIPIPEDSDDEIPLSSKFQVKSNAGESINRSSNSGERKPLLSKYDQNGSASTE-- 2461
              ++R I   EDS+DE PLS +F  KS+ GES ++S +S E+KPL +K  QNGS S +  
Sbjct: 180  SIRRRVIEESEDSEDEKPLSRRFTSKSSLGESTSKSYDSDEKKPLAAKVQQNGSVSRDGP 239

Query: 2460 -RKPSTNLKKRPGDGVKTTDESYLKKPKLSEAATPHKNKEASIKAEMR------------ 2320
              K ++   KRP   VK+ ++S +KKPKLS   T   NK+A++K E              
Sbjct: 240  MNKSASLSNKRPPGEVKSLNQSSVKKPKLSSPITSISNKQAAVKPEPEPKAEDDDDNIPL 299

Query: 2319 --------------EEDDEDHVPISHRMXXXXXXXXXXXXXKN-ITKPIXXXXXXXXXXX 2185
                          +++D+D+VPI+ R+                 +  +           
Sbjct: 300  SQRGKKSQAATSKPKDEDDDNVPIAQRIKKSPASVSKSSAPVKKASTVVSPSLKKVNKNS 359

Query: 2184 XXXXXXXXXXXXXXXXXXSGEGQKWTTLVHNGVIFPPPYKPHGVKMLYKGKPVDLTPEQE 2005
                              SGEGQKWTTLVHNGVIFPPPY PHGVKMLYK +P+ LTPEQE
Sbjct: 360  KKVIKKTAYTKSSKVPPGSGEGQKWTTLVHNGVIFPPPYNPHGVKMLYKRQPITLTPEQE 419

Query: 2004 EVATMYAVMLETDYMNKPKFKENFMADWRKILGKNHTIQSLEHCDFTPIYEWHXXXXXXX 1825
            EVATM+AVML+TDYMNKP+FKENF +DW+K+LGKNHTIQ+LE CDF PIYEWH       
Sbjct: 420  EVATMFAVMLDTDYMNKPRFKENFFSDWKKMLGKNHTIQNLEDCDFGPIYEWHQQEKEKK 479

Query: 1824 XXXXXXXXXXXXXXXXXXXXKYMWAIVNGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKR 1645
                                KYMWAIV+GVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKR
Sbjct: 480  KQMTTEEKKALKEDKLQQEEKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKR 539

Query: 1644 IRPSDITINIGKDAPIPECPIPGESWKEIRHDNTVTWLAYWNDPINPKEFKYVFLAASST 1465
            IRP DITINIGKDAPIPECPIPGE WKE+R+DNTVTWLA+W DPIN KEFKYVFLAASST
Sbjct: 540  IRPRDITINIGKDAPIPECPIPGERWKEVRNDNTVTWLAFWIDPINQKEFKYVFLAASST 599

Query: 1464 LKGQSDKEKYEKARLLKDYILGIRAAYTKDFTS-KDPAKRQIAVATYLIDKLALRAGNEK 1288
            LKGQSDKEKYEKARLLKDYI GIRAAYTKDFT+ KDP K+QIAVATYLIDKLALRAGNEK
Sbjct: 600  LKGQSDKEKYEKARLLKDYIHGIRAAYTKDFTNNKDPMKKQIAVATYLIDKLALRAGNEK 659

Query: 1287 DDDEADTVGCCTLKVENVEPVPPNTLKFDFLGKDSIRYQNEVEVETAVFKAIQQFRSGKK 1108
            DDDEADTVGCCTLKVENVEPVPPN LKFDFLGKDSIRYQNEV+VE AVFKAIQQFRSGK+
Sbjct: 660  DDDEADTVGCCTLKVENVEPVPPNILKFDFLGKDSIRYQNEVQVEPAVFKAIQQFRSGKE 719

Query: 1107 GGDDLFDRLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSRETRGGDVAEKVVVYQ 928
            G +DLFDRLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLS+ET+GG+VAEKVVVYQ
Sbjct: 720  GSEDLFDRLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSKETKGGEVAEKVVVYQ 779

Query: 927  HANKEVAIICNHQRTVSKSHSAQMLRLNEKIEELKGVVEELQTDLARAKKGKPPLKSADG 748
            HANKEVAIICNHQRTVSKSHSAQM RLNEKI+ELK  +EEL+TDL+R KKGKPP K ADG
Sbjct: 780  HANKEVAIICNHQRTVSKSHSAQMSRLNEKIDELKTAMEELKTDLSRVKKGKPPSKGADG 839

Query: 747  KPKRNLNPDALERKIAQTTAKIEKMERDKETKEDLKTVALGTSKINYLDPRITVAWCKRH 568
            KPKRNLNP+ALERK+AQ  AKIEKMERDKETKEDLKTVALGTSKINYLDPRITVAWCKRH
Sbjct: 840  KPKRNLNPEALERKMAQINAKIEKMERDKETKEDLKTVALGTSKINYLDPRITVAWCKRH 899

Query: 567  EVPIEKIFNKSLLAKFAWAMDVDPGFRF 484
            EVPIEKIFNKSLLAKFAW+MDVDP FRF
Sbjct: 900  EVPIEKIFNKSLLAKFAWSMDVDPSFRF 927


>dbj|BAK32958.1| topoisomerase I [Ophiorrhiza pedunculata]
          Length = 920

 Score = 1115 bits (2883), Expect = 0.0
 Identities = 593/919 (64%), Positives = 664/919 (72%), Gaps = 33/919 (3%)
 Frame = -3

Query: 3162 MAVEACDKQKLXXXXXXXXEPLVFKRXXXXXXXXXXXSEAKKSLSQKHDRQLGRPAPDVR 2983
            MAVEAC    L         P++FKR           SE KK   QKH  Q      DVR
Sbjct: 1    MAVEACTTTNLMEDMEDDEGPVIFKRSNPASKQNQANSEKKKLSLQKHVGQSAVHTSDVR 60

Query: 2982 SQNGQSTIVKKSKTVPLSKTPPVKYPLTSPKSSNTSGKALALKSPEVDSKPSTSVTDKSN 2803
              NG+++  +K +  P +KTPPVK PL+SPK+SN+S KA  + SP  +SKPS S T  + 
Sbjct: 61   PANGENSSAQKGRIQPSAKTPPVKSPLSSPKASNSSAKASPITSPGANSKPSASATSTAK 120

Query: 2802 SVKHQIKD----EKLSTEATGEPNEDSQDSEDDKPLSARLPAGLSKVNSNHAKKSPNTST 2635
               H        E   +    + N +S+ S+D+KPLSAR     SK  SNHA K    S 
Sbjct: 121  QQNHHKSSAAFIEPKPSVPAAKANSNSESSDDEKPLSARTFGCSSKGKSNHANKEGGDSC 180

Query: 2634 LSQKRRIPIPEDSDDEIPLSSKFQVKSNAGESINRSSNSGERKPLLSKYDQNGSASTE-- 2461
              ++  I   EDS+DE PLS +F  KS+ GES ++S +S E+KPL +K   NGSAS +  
Sbjct: 181  SIRRPVIEESEDSEDEKPLSRRFTSKSSLGESTSKSYDSDEKKPLAAKVQPNGSASRDSP 240

Query: 2460 -RKPSTNLKKRPGDGVKTTDESYLKKPKLSEAATPHKNKEASIKAEMREEDDE------- 2305
              K ++   KRP   VK+ ++S LKKPKLS   T   NK+A++K E + EDD+       
Sbjct: 241  MNKSASLSNKRPPGEVKSLNQSSLKKPKLSSPITSISNKQAAVKPEPKAEDDDDNIPLSQ 300

Query: 2304 -----------------DHVPISHRMXXXXXXXXXXXXXKN-ITKPIXXXXXXXXXXXXX 2179
                             D+VPIS R+                 +  +             
Sbjct: 301  RGKKSQTATSKPKDEDDDNVPISQRIKKSPASVSKSSAPVKKASTVVSPSLKKVNKKSKK 360

Query: 2178 XXXXXXXXXXXXXXXXSGEGQKWTTLVHNGVIFPPPYKPHGVKMLYKGKPVDLTPEQEEV 1999
                            SGEGQKWTTLVHNGVIFPPPYKPHGVKMLYK +P+ LTPEQEEV
Sbjct: 361  VIKKTAYTKSSKVPPGSGEGQKWTTLVHNGVIFPPPYKPHGVKMLYKRQPITLTPEQEEV 420

Query: 1998 ATMYAVMLETDYMNKPKFKENFMADWRKILGKNHTIQSLEHCDFTPIYEWHXXXXXXXXX 1819
            ATM+AVML+TDYMNKP+FKENF +DW+K+LGKNHTIQ+LE CDF PIYEWH         
Sbjct: 421  ATMFAVMLDTDYMNKPRFKENFFSDWKKMLGKNHTIQNLEDCDFGPIYEWHQQEKEKKKQ 480

Query: 1818 XXXXXXXXXXXXXXXXXXKYMWAIVNGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIR 1639
                              KYMWAIV+GVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIR
Sbjct: 481  MTTEEKKALKEEKLQQEEKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIR 540

Query: 1638 PSDITINIGKDAPIPECPIPGESWKEIRHDNTVTWLAYWNDPINPKEFKYVFLAASSTLK 1459
            P DITINIGKDAPIPECPIPGE WKE+R+DNTVTWLAYWNDPIN KEFKYVFLAASSTLK
Sbjct: 541  PRDITINIGKDAPIPECPIPGERWKEVRNDNTVTWLAYWNDPINQKEFKYVFLAASSTLK 600

Query: 1458 GQSDKEKYEKARLLKDYILGIRAAYTKDFTS-KDPAKRQIAVATYLIDKLALRAGNEKDD 1282
            GQSDKEKYEKARLLKDYI GIRAAYTKDFT+ KDP K+QIAVATYLIDKLALRAGNEKDD
Sbjct: 601  GQSDKEKYEKARLLKDYIHGIRAAYTKDFTNNKDPMKKQIAVATYLIDKLALRAGNEKDD 660

Query: 1281 DEADTVGCCTLKVENVEPVPPNTLKFDFLGKDSIRYQNEVEVETAVFKAIQQFRSGKKGG 1102
            DEADTVGCCTLKVENVEPVPPN LKFDFLGKDSIRYQNEV+VE AVFKAI QFRSGK+G 
Sbjct: 661  DEADTVGCCTLKVENVEPVPPNILKFDFLGKDSIRYQNEVQVEPAVFKAIHQFRSGKEGS 720

Query: 1101 DDLFDRLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSRETRGGDVAEKVVVYQHA 922
            +DLFDRLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLS++T GG+VAEKVVVYQHA
Sbjct: 721  EDLFDRLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSKKTNGGEVAEKVVVYQHA 780

Query: 921  NKEVAIICNHQRTVSKSHSAQMLRLNEKIEELKGVVEELQTDLARAKKGKPPLKSADGKP 742
            NKEVAIICNHQRTVSKSHSAQM RLNEKI+ELK  +EEL+TDL+RAKKGKP  K ADGKP
Sbjct: 781  NKEVAIICNHQRTVSKSHSAQMSRLNEKIDELKTALEELKTDLSRAKKGKPLSKGADGKP 840

Query: 741  KRNLNPDALERKIAQTTAKIEKMERDKETKEDLKTVALGTSKINYLDPRITVAWCKRHEV 562
            KRNLNP+ALERKIAQT AKIEKMERDKETKEDLKTVALGTSKINYLDPRITVAWCKRHEV
Sbjct: 841  KRNLNPEALERKIAQTNAKIEKMERDKETKEDLKTVALGTSKINYLDPRITVAWCKRHEV 900

Query: 561  PIEKIFNKSLLAKFAWAMD 505
            PIEKIFNKSLLAKFAWAM+
Sbjct: 901  PIEKIFNKSLLAKFAWAMN 919


>dbj|BAK32962.1| topoisomerase I [Ophiorrhiza trichocarpon var. glabra]
          Length = 920

 Score = 1112 bits (2877), Expect = 0.0
 Identities = 592/919 (64%), Positives = 664/919 (72%), Gaps = 33/919 (3%)
 Frame = -3

Query: 3162 MAVEACDKQKLXXXXXXXXEPLVFKRXXXXXXXXXXXSEAKKSLSQKHDRQLGRPAPDVR 2983
            MAVEAC    L         P++FKR           SE KK   Q+H  Q      DVR
Sbjct: 1    MAVEACTTTNLMEDMEDDEGPVIFKRSNPASKQNQANSEKKKLSLQRHVGQSAVHTSDVR 60

Query: 2982 SQNGQSTIVKKSKTVPLSKTPPVKYPLTSPKSSNTSGKALALKSPEVDSKPSTSVTDKSN 2803
              NG+++  +K +  P +KTPPVK PL+SPK+SN+S KA  + S   +SKPS S T  + 
Sbjct: 61   PANGENSSAQKGRIQPSAKTPPVKSPLSSPKASNSSAKASPITSAGANSKPSASATSTAK 120

Query: 2802 SVKHQIKD----EKLSTEATGEPNEDSQDSEDDKPLSARLPAGLSKVNSNHAKKSPNTST 2635
               H        E   +    + N +S+ S+D+KPLSAR     SK  SNHA K    S 
Sbjct: 121  QQNHHKSSAAFIEPKPSVPAAKANSNSESSDDEKPLSARTFGCSSKGKSNHANKEGGDSC 180

Query: 2634 LSQKRRIPIPEDSDDEIPLSSKFQVKSNAGESINRSSNSGERKPLLSKYDQNGSASTE-- 2461
              ++  I   EDS+DE PLS +F  KS+ GES ++S +S E+KPL +K   NGSAS +  
Sbjct: 181  SIRRPVIEESEDSEDEKPLSRRFTSKSSLGESTSKSYDSDEKKPLAAKVQPNGSASRDSP 240

Query: 2460 -RKPSTNLKKRPGDGVKTTDESYLKKPKLSEAATPHKNKEASIKAEMREEDDE------- 2305
              K ++   KRP   VK+ ++S LKKPKLS   T   NK+A++K E + EDD+       
Sbjct: 241  MNKSASLSNKRPPGEVKSLNQSSLKKPKLSSPITSISNKQAAVKPEPKAEDDDDNIPLSQ 300

Query: 2304 -----------------DHVPISHRMXXXXXXXXXXXXXKN-ITKPIXXXXXXXXXXXXX 2179
                             D+VPIS R+                 +  +             
Sbjct: 301  RGKKSQTATSKPKDEDDDNVPISQRIKKSPASVSKSSAPVKKASTVVSPSLKKVNKKSKK 360

Query: 2178 XXXXXXXXXXXXXXXXSGEGQKWTTLVHNGVIFPPPYKPHGVKMLYKGKPVDLTPEQEEV 1999
                            SGEGQKWTTLVHNGVIFPPPYKPHGVKMLYK +P+ LTPEQEEV
Sbjct: 361  VIKKTAYTKSSKVPPGSGEGQKWTTLVHNGVIFPPPYKPHGVKMLYKRQPITLTPEQEEV 420

Query: 1998 ATMYAVMLETDYMNKPKFKENFMADWRKILGKNHTIQSLEHCDFTPIYEWHXXXXXXXXX 1819
            ATM+AVML+TDYMNKP+FKENF +DW+K+LGKNHTIQ+LE CDF PIYEWH         
Sbjct: 421  ATMFAVMLDTDYMNKPRFKENFFSDWKKMLGKNHTIQNLEDCDFGPIYEWHQQEKEKKKQ 480

Query: 1818 XXXXXXXXXXXXXXXXXXKYMWAIVNGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIR 1639
                              KYMWAIV+GVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIR
Sbjct: 481  MTTEEKKALKEEKLQQEEKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIR 540

Query: 1638 PSDITINIGKDAPIPECPIPGESWKEIRHDNTVTWLAYWNDPINPKEFKYVFLAASSTLK 1459
            P DITINIGKDAPIPECPIPGE WKE+R+DNTVTWLAYWNDPIN KEFKYVFLAASSTLK
Sbjct: 541  PRDITINIGKDAPIPECPIPGERWKEVRNDNTVTWLAYWNDPINQKEFKYVFLAASSTLK 600

Query: 1458 GQSDKEKYEKARLLKDYILGIRAAYTKDFTS-KDPAKRQIAVATYLIDKLALRAGNEKDD 1282
            GQSDKEKYEKARLLKDYI GIRAAYTKDFT+ KDP K+QIAVATYLIDKLALRAGNEKDD
Sbjct: 601  GQSDKEKYEKARLLKDYIHGIRAAYTKDFTNNKDPMKKQIAVATYLIDKLALRAGNEKDD 660

Query: 1281 DEADTVGCCTLKVENVEPVPPNTLKFDFLGKDSIRYQNEVEVETAVFKAIQQFRSGKKGG 1102
            DEADTVGCCTLKVENVEPVPPN LKFDFLGKDSIRYQNEV+VE AVFKAIQQFRSGK+G 
Sbjct: 661  DEADTVGCCTLKVENVEPVPPNILKFDFLGKDSIRYQNEVQVEPAVFKAIQQFRSGKEGS 720

Query: 1101 DDLFDRLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSRETRGGDVAEKVVVYQHA 922
            +DLFDRLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLS++T GG+VAEKVVVYQHA
Sbjct: 721  EDLFDRLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSKKTNGGEVAEKVVVYQHA 780

Query: 921  NKEVAIICNHQRTVSKSHSAQMLRLNEKIEELKGVVEELQTDLARAKKGKPPLKSADGKP 742
            NKEVAIICNHQRTVSKSHSAQM RLNEKI+ELK  +EEL+TDL+RAKKGKP  K ADGKP
Sbjct: 781  NKEVAIICNHQRTVSKSHSAQMSRLNEKIDELKTALEELKTDLSRAKKGKPLSKGADGKP 840

Query: 741  KRNLNPDALERKIAQTTAKIEKMERDKETKEDLKTVALGTSKINYLDPRITVAWCKRHEV 562
            KRNLNP+ALERKIAQT AKIEKMERDKETKEDLKTVALGTSKINYLDPRITVAWCKRHEV
Sbjct: 841  KRNLNPEALERKIAQTNAKIEKMERDKETKEDLKTVALGTSKINYLDPRITVAWCKRHEV 900

Query: 561  PIEKIFNKSLLAKFAWAMD 505
            PIEKIFNKSLLAKFAWAM+
Sbjct: 901  PIEKIFNKSLLAKFAWAMN 919


>dbj|BAK32961.1| topoisomerase I [Ophiorrhiza ridleyana]
          Length = 926

 Score = 1099 bits (2842), Expect = 0.0
 Identities = 583/927 (62%), Positives = 663/927 (71%), Gaps = 34/927 (3%)
 Frame = -3

Query: 3162 MAVEACDKQKLXXXXXXXXEPLVFKRXXXXXXXXXXXSEAKKSLSQKHDRQLGRPAPDVR 2983
            MAVEAC    L         P++FKR           +E KK   QKH  Q      DVR
Sbjct: 1    MAVEACTTTNLMEDMEDDEGPVIFKRSNPTSKQNQANAEKKKLSLQKHVGQSAVHTSDVR 60

Query: 2982 SQNGQSTIVKKSKTVPLSKTPPVKYPLTSPKSSNTSGKALALKSPEVDSKPSTSVTDKSN 2803
              NG+S+  +K +  P ++TPPVK PL+SPK+SN+S KA  + SP  +SK S S T  + 
Sbjct: 61   PANGESSSAQKGRIQPSAETPPVKSPLSSPKASNSSAKASPITSPGANSKLSASATSTAK 120

Query: 2802 SVKHQIKD----EKLSTEATGEPNEDSQDSEDDKPLSARLPAGLSKVNSNHAKKSPNTST 2635
               H        E   +    + N +S+ S+D+KPL AR     S   SNHA K    S 
Sbjct: 121  QQNHHKSSAAFIEPKPSVPAAKANSNSESSDDEKPLIARTSGCSSMGKSNHANKEGGDSC 180

Query: 2634 LSQKRRIPIPEDSDDEIPLSSKFQVKSNAGESINRSSNSGERKPLLSKYDQNGSASTE-- 2461
              ++  I   EDS+DE PLS +F  KS+ GES ++S +S E+KPL +K  QNGSAS E  
Sbjct: 181  SIRRPVIEESEDSEDEKPLSRRFPSKSSLGESTSKSYDSDEKKPLAAKVQQNGSASPEGP 240

Query: 2460 --RKPSTNLKKRPGDGVKTTDESYLKKPKLSEAATPHKNKEASIKAEMREEDDED----- 2302
              +  S + K+ PG+ VK+ ++S LKKPKLS   T   NK+A++K E + EDD+D     
Sbjct: 241  MNKSASLSNKRAPGE-VKSLNQSSLKKPKLSSPITSISNKQAAVKPEPKAEDDDDNIPLS 299

Query: 2301 -------------------HVPISHRMXXXXXXXXXXXXXKN-ITKPIXXXXXXXXXXXX 2182
                               H PIS R+                 +  +            
Sbjct: 300  QRGKKSQTAASKPKDEDDDHAPISQRIKKSPVSVSKSSAPVKKASTVVSTSLKKVNKKSK 359

Query: 2181 XXXXXXXXXXXXXXXXXSGEGQKWTTLVHNGVIFPPPYKPHGVKMLYKGKPVDLTPEQEE 2002
                             SGEGQKWTTLVHNGV+FPPPYKPHGVKMLYK +P+ LTPEQEE
Sbjct: 360  KVIRKTAYTKSSKVPPGSGEGQKWTTLVHNGVMFPPPYKPHGVKMLYKRQPLTLTPEQEE 419

Query: 2001 VATMYAVMLETDYMNKPKFKENFMADWRKILGKNHTIQSLEHCDFTPIYEWHXXXXXXXX 1822
            VATM+AVML+TDYMNKP+FKENF +DW+KILGKNHTIQ+LE CDF PIYEWH        
Sbjct: 420  VATMFAVMLDTDYMNKPRFKENFFSDWKKILGKNHTIQNLEDCDFGPIYEWHQQEKEKKK 479

Query: 1821 XXXXXXXXXXXXXXXXXXXKYMWAIVNGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRI 1642
                               KYMWAIV+GVKEKVGNFRVEPPGLFRGRGEHPK+GKLKKRI
Sbjct: 480  QMTTEEKKALKEERLQQEEKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKVGKLKKRI 539

Query: 1641 RPSDITINIGKDAPIPECPIPGESWKEIRHDNTVTWLAYWNDPINPKEFKYVFLAASSTL 1462
            RP DITINIGKDAPIPECPIPGE WKE+R+DNTVTWLAYWNDP+N KE KYVFLAASSTL
Sbjct: 540  RPRDITINIGKDAPIPECPIPGERWKEVRNDNTVTWLAYWNDPVNIKECKYVFLAASSTL 599

Query: 1461 KGQSDKEKYEKARLLKDYILGIRAAYTKDFTS-KDPAKRQIAVATYLIDKLALRAGNEKD 1285
            KGQS KEKYEKAR+LKDYI GIRAAYTK FT+ KDP K+QIAVATYLIDKLALRAGNEKD
Sbjct: 600  KGQSVKEKYEKARVLKDYIHGIRAAYTKGFTNNKDPMKKQIAVATYLIDKLALRAGNEKD 659

Query: 1284 DDEADTVGCCTLKVENVEPVPPNTLKFDFLGKDSIRYQNEVEVETAVFKAIQQFRSGKKG 1105
            DDEADTVGCCTLKVENVEPVPPN LK DF+GKDSIRYQNEV+VE AVFKAIQQFRSGK+G
Sbjct: 660  DDEADTVGCCTLKVENVEPVPPNILKIDFIGKDSIRYQNEVQVEPAVFKAIQQFRSGKEG 719

Query: 1104 GDDLFDRLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSRETRGGDVAEKVVVYQH 925
             +DLFDRLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLS+ET+GG +AEKV VYQH
Sbjct: 720  SEDLFDRLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSKETKGGKIAEKVAVYQH 779

Query: 924  ANKEVAIICNHQRTVSKSHSAQMLRLNEKIEELKGVVEELQTDLARAKKGKPPLKSADGK 745
            ANKEVAIICNHQRTVSKSHSAQM RLNEKI+ELK  +EEL+TDL+RAKKGKPP K ADG+
Sbjct: 780  ANKEVAIICNHQRTVSKSHSAQMSRLNEKIDELKTALEELKTDLSRAKKGKPPSKDADGE 839

Query: 744  PKRNLNPDALERKIAQTTAKIEKMERDKETKEDLKTVALGTSKINYLDPRITVAWCKRHE 565
            PKRNLNP++LERKIAQT AKIEKMERDK+TKEDLK VAL TSKI+YLDPRITVAWCKR E
Sbjct: 840  PKRNLNPESLERKIAQTNAKIEKMERDKKTKEDLKAVALSTSKISYLDPRITVAWCKRQE 899

Query: 564  VPIEKIFNKSLLAKFAWAMDVDPGFRF 484
            VPIEK+FNKSLLAKFAWAMDVDP FRF
Sbjct: 900  VPIEKMFNKSLLAKFAWAMDVDPSFRF 926


>dbj|BAG31373.1| topoisomerase I [Ophiorrhiza pumila]
          Length = 926

 Score = 1098 bits (2841), Expect = 0.0
 Identities = 584/927 (62%), Positives = 663/927 (71%), Gaps = 34/927 (3%)
 Frame = -3

Query: 3162 MAVEACDKQKLXXXXXXXXEPLVFKRXXXXXXXXXXXSEAKKSLSQKHDRQLGRPAPDVR 2983
            MAVEAC    L         P++FKR           SE KK   QKH  Q      DVR
Sbjct: 1    MAVEACTTPNLMEDMEDDEGPVIFKRSNPASKQNQANSEKKKLSLQKHVGQSAVHTSDVR 60

Query: 2982 SQNGQSTIVKKSKTVPLSKTPPVKYPLTSPKSSNTSGKALALKSPEVDSKPSTSVTDKSN 2803
              NG+S+  +K +  P ++TPPVK PL+SPK+SN+S KA  + SP  +SK S S T  + 
Sbjct: 61   PANGESSSAQKGRIQPSAETPPVKSPLSSPKASNSSAKASPITSPGANSKLSASATSTAK 120

Query: 2802 SVKHQIKD----EKLSTEATGEPNEDSQDSEDDKPLSARLPAGLSKVNSNHAKKSPNTST 2635
               H        E   +    + N +S+ S+D+KPL AR     SK  SNHA K    S 
Sbjct: 121  QQNHHKSSAAFIEPKPSVPAAKANSNSESSDDEKPLIARTSGCSSKGKSNHANKEGGDSC 180

Query: 2634 LSQKRRIPIPEDSDDEIPLSSKFQVKSNAGESINRSSNSGERKPLLSKYDQNGSASTE-- 2461
              ++  I   EDS+DE PLS +F  KS+ GES ++S +S E+KPL +K  QNGSAS +  
Sbjct: 181  SIRRPVIEESEDSEDEKPLSRRFPSKSSLGESTSKSHDSDEKKPLAAKVQQNGSASRDGP 240

Query: 2460 --RKPSTNLKKRPGDGVKTTDESYLKKPKLSEAATPHKNKEASIKAEMREEDDE------ 2305
              +  S + K+ PG+ VK+ ++S LKKPKLS   T   NK+A++K E + EDD+      
Sbjct: 241  MNKSASLSNKRAPGE-VKSLNQSSLKKPKLSSTITSISNKQAAVKPEPKAEDDDDNIPLS 299

Query: 2304 ------------------DHVPISHRMXXXXXXXXXXXXXKN-ITKPIXXXXXXXXXXXX 2182
                              D+ PIS R+                 +  +            
Sbjct: 300  QRGKKSQTAASKPKDEDDDNAPISQRIKKSPASVSKSSAPVKKASTVVSPSLKKVNKKSK 359

Query: 2181 XXXXXXXXXXXXXXXXXSGEGQKWTTLVHNGVIFPPPYKPHGVKMLYKGKPVDLTPEQEE 2002
                             SGEGQKWTTLVHNGV+FPPPYKPHGVKMLYK +P+ LTPEQEE
Sbjct: 360  KVIKKTAYTKSSKVPPGSGEGQKWTTLVHNGVMFPPPYKPHGVKMLYKRQPLTLTPEQEE 419

Query: 2001 VATMYAVMLETDYMNKPKFKENFMADWRKILGKNHTIQSLEHCDFTPIYEWHXXXXXXXX 1822
            VATM+A ML+TDYMNKP+FKENF +DW+KILGKNHTIQ+LE CDF PIYEWH        
Sbjct: 420  VATMFAAMLDTDYMNKPRFKENFFSDWKKILGKNHTIQNLEDCDFGPIYEWHQQEKEKKK 479

Query: 1821 XXXXXXXXXXXXXXXXXXXKYMWAIVNGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRI 1642
                               KYMWAIV+GVKEKVGNFRVEPPGLFRGRGEHPK+GKLKKRI
Sbjct: 480  QMTTEEKKALKEERLQLEEKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKVGKLKKRI 539

Query: 1641 RPSDITINIGKDAPIPECPIPGESWKEIRHDNTVTWLAYWNDPINPKEFKYVFLAASSTL 1462
            RP DITINIGKDAPIPECPIPGE WKE+R+DNTVTWLAYWNDP+N KE KYVFLAASSTL
Sbjct: 540  RPRDITINIGKDAPIPECPIPGERWKEVRNDNTVTWLAYWNDPVNLKECKYVFLAASSTL 599

Query: 1461 KGQSDKEKYEKARLLKDYILGIRAAYTKDFTS-KDPAKRQIAVATYLIDKLALRAGNEKD 1285
            KGQSDKEKYEKARLLKDYI GIRAAYTKDFT+ KDP K+Q+AVATYLIDKLALRAGNEKD
Sbjct: 600  KGQSDKEKYEKARLLKDYIHGIRAAYTKDFTNNKDPMKKQVAVATYLIDKLALRAGNEKD 659

Query: 1284 DDEADTVGCCTLKVENVEPVPPNTLKFDFLGKDSIRYQNEVEVETAVFKAIQQFRSGKKG 1105
            DDEADTVGCCTLKVENVEPVPPN LK DF+GKDSIRYQNEV+VE AVFKAIQQFRSGK+G
Sbjct: 660  DDEADTVGCCTLKVENVEPVPPNILKIDFIGKDSIRYQNEVQVEPAVFKAIQQFRSGKEG 719

Query: 1104 GDDLFDRLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSRETRGGDVAEKVVVYQH 925
             +DLFDRLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLS+ET+GG VAEKV VYQ 
Sbjct: 720  SEDLFDRLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSKETKGGKVAEKVGVYQR 779

Query: 924  ANKEVAIICNHQRTVSKSHSAQMLRLNEKIEELKGVVEELQTDLARAKKGKPPLKSADGK 745
            ANKEVAIICNHQRTVSKSHSAQM RLNEKI+ELK  +EEL+TDL+RAKKGKPP K  DG+
Sbjct: 780  ANKEVAIICNHQRTVSKSHSAQMSRLNEKIDELKTALEELKTDLSRAKKGKPPSKGDDGE 839

Query: 744  PKRNLNPDALERKIAQTTAKIEKMERDKETKEDLKTVALGTSKINYLDPRITVAWCKRHE 565
            PKRNLNP+ALERKIAQT AKIEKMERDK+TKEDLK VAL TSKI+YLDPRITVAWCKR E
Sbjct: 840  PKRNLNPEALERKIAQTNAKIEKMERDKKTKEDLKAVALSTSKISYLDPRITVAWCKRQE 899

Query: 564  VPIEKIFNKSLLAKFAWAMDVDPGFRF 484
            VPIEK+FNKSLLAKFAWAMDVDP FRF
Sbjct: 900  VPIEKMFNKSLLAKFAWAMDVDPSFRF 926


>dbj|BAK32956.1| topoisomerase I [Ophiorrhiza fucosa]
          Length = 926

 Score = 1097 bits (2836), Expect = 0.0
 Identities = 583/927 (62%), Positives = 662/927 (71%), Gaps = 34/927 (3%)
 Frame = -3

Query: 3162 MAVEACDKQKLXXXXXXXXEPLVFKRXXXXXXXXXXXSEAKKSLSQKHDRQLGRPAPDVR 2983
            MAVEAC    L         P++FKR           SE KK   QKH  Q      DVR
Sbjct: 1    MAVEACTTTNLMEDMEDDEGPVIFKRSNPASKQNQANSEKKKLSLQKHVGQSAVHTSDVR 60

Query: 2982 SQNGQSTIVKKSKTVPLSKTPPVKYPLTSPKSSNTSGKALALKSPEVDSKPSTSVTDKSN 2803
              NG+S+  +K +  P ++TPPVK PL+SPK+SN+S KA  + SP  +SK S S T  + 
Sbjct: 61   PANGESSSAQKGRIQPSAETPPVKSPLSSPKASNSSAKASPITSPGANSKLSASATSTAK 120

Query: 2802 SVKHQIKD----EKLSTEATGEPNEDSQDSEDDKPLSARLPAGLSKVNSNHAKKSPNTST 2635
               H        E   +    + N +S+ S+D+KPL AR     SK  SNHA K    S 
Sbjct: 121  QQNHHKSSAAFIEPKPSVPPAKANSNSESSDDEKPLIARTSGCSSKGKSNHANKEGGDSC 180

Query: 2634 LSQKRRIPIPEDSDDEIPLSSKFQVKSNAGESINRSSNSGERKPLLSKYDQNGSASTE-- 2461
              ++  +   EDS+DE PLS +F  KS+ GES ++S +S E+KPL +K  QNGSAS +  
Sbjct: 181  SIRRPVVEESEDSEDEKPLSRRFPSKSSLGESTSKSYDSDEKKPLAAKVQQNGSASRDGP 240

Query: 2460 --RKPSTNLKKRPGDGVKTTDESYLKKPKLSEAATPHKNKEASIKAEMREEDDE------ 2305
              +  S + K+ PG+ VK+ ++S LKKPKLS   T   NK+A++K E + EDD+      
Sbjct: 241  MNKSASLSNKRAPGE-VKSLNQSSLKKPKLSSPITSISNKQAAVKPEPKAEDDDDNIPLS 299

Query: 2304 ------------------DHVPISHRMXXXXXXXXXXXXXKN-ITKPIXXXXXXXXXXXX 2182
                              D+ PIS R+                 +  +            
Sbjct: 300  QRGKKSQTAASKPKDEDDDNAPISQRIKKSPASVSKSSAPVKKASTVVSPSLKKVNKKSK 359

Query: 2181 XXXXXXXXXXXXXXXXXSGEGQKWTTLVHNGVIFPPPYKPHGVKMLYKGKPVDLTPEQEE 2002
                             SGEGQKWTTLVHNGV+FPPPYKPHGVKMLYK +P+ LTPEQEE
Sbjct: 360  KVIKKTAYTKSSKVPPGSGEGQKWTTLVHNGVMFPPPYKPHGVKMLYKRQPLTLTPEQEE 419

Query: 2001 VATMYAVMLETDYMNKPKFKENFMADWRKILGKNHTIQSLEHCDFTPIYEWHXXXXXXXX 1822
            VATM+A ML+TDYMNKP+FKENF +DW+KILGKNHTIQ+LE CDF PIYEWH        
Sbjct: 420  VATMFAAMLDTDYMNKPRFKENFFSDWKKILGKNHTIQNLEDCDFGPIYEWHQQEREKKK 479

Query: 1821 XXXXXXXXXXXXXXXXXXXKYMWAIVNGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRI 1642
                               KYMWAIV+GVKEKVGNFRVEPPGLFRGRGEHPK+GKLKKRI
Sbjct: 480  QMTTEEKKALKDERLQLEEKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKVGKLKKRI 539

Query: 1641 RPSDITINIGKDAPIPECPIPGESWKEIRHDNTVTWLAYWNDPINPKEFKYVFLAASSTL 1462
             P DITINIGKDAPIPECPIPGE WKE+R+DNTVTWLAYWNDP+N KE KYVFLA SSTL
Sbjct: 540  HPRDITINIGKDAPIPECPIPGERWKEVRNDNTVTWLAYWNDPVNLKECKYVFLAPSSTL 599

Query: 1461 KGQSDKEKYEKARLLKDYILGIRAAYTKDFTS-KDPAKRQIAVATYLIDKLALRAGNEKD 1285
            KGQSDKEKYEKARLLKDYI GIRAAYTKDFT+ KDP K+QIAVATYLIDKLALRAGNEKD
Sbjct: 600  KGQSDKEKYEKARLLKDYIHGIRAAYTKDFTNNKDPMKKQIAVATYLIDKLALRAGNEKD 659

Query: 1284 DDEADTVGCCTLKVENVEPVPPNTLKFDFLGKDSIRYQNEVEVETAVFKAIQQFRSGKKG 1105
            DDEADTVGCCTLKVENVEPVPPN LK DF+GKDSIRYQNEV+VE AVFKAIQQFRSGK+G
Sbjct: 660  DDEADTVGCCTLKVENVEPVPPNILKIDFIGKDSIRYQNEVQVEPAVFKAIQQFRSGKEG 719

Query: 1104 GDDLFDRLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSRETRGGDVAEKVVVYQH 925
             +DLFDRLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLS+ET+GG VAEKV VYQH
Sbjct: 720  SEDLFDRLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSKETKGGKVAEKVGVYQH 779

Query: 924  ANKEVAIICNHQRTVSKSHSAQMLRLNEKIEELKGVVEELQTDLARAKKGKPPLKSADGK 745
            ANKEVAIICNHQRTVSKSHSAQM RLNEKI+ELK  +EEL+TDL+RAKKGKPP K  DG+
Sbjct: 780  ANKEVAIICNHQRTVSKSHSAQMSRLNEKIDELKTALEELKTDLSRAKKGKPPSKGDDGE 839

Query: 744  PKRNLNPDALERKIAQTTAKIEKMERDKETKEDLKTVALGTSKINYLDPRITVAWCKRHE 565
            PKRNLNP+ALERKIAQT AKIEKMERDK+TKEDLK VAL TSKI+YLDPRITVAWCKR E
Sbjct: 840  PKRNLNPEALERKIAQTNAKIEKMERDKKTKEDLKAVALSTSKISYLDPRITVAWCKRQE 899

Query: 564  VPIEKIFNKSLLAKFAWAMDVDPGFRF 484
            VPIEK+FNKSLLAKFAWAMDVDP FRF
Sbjct: 900  VPIEKMFNKSLLAKFAWAMDVDPSFRF 926


>dbj|BAG31374.1| topoisomerase I [Ophiorrhiza liukiuensis]
          Length = 926

 Score = 1096 bits (2834), Expect = 0.0
 Identities = 584/926 (63%), Positives = 661/926 (71%), Gaps = 33/926 (3%)
 Frame = -3

Query: 3162 MAVEACDKQKLXXXXXXXXEPLVFKRXXXXXXXXXXXSEAKKSLSQKHDRQLGRPAPDVR 2983
            MAVEAC    L         P++FKR           SE KK   QKH  Q      DVR
Sbjct: 1    MAVEACTTPNLMEDMEDDEGPVIFKRSNPASKQNQANSEKKKLSLQKHVGQSAVHTSDVR 60

Query: 2982 SQNGQSTIVKKSKTVPLSKTPPVKYPLTSPKSSNTSGKALALKSPEVDSKPSTSVTDKSN 2803
              NG+S+  +K +  P ++TPPVK PL+SPK+SN+S KA  + SP  +SK S S T  + 
Sbjct: 61   PANGESSSAQKGRIQPSAETPPVKSPLSSPKASNSSAKASPITSPGANSKLSASATSTAK 120

Query: 2802 SVKHQIKD----EKLSTEATGEPNEDSQDSEDDKPLSARLPAGLSKVNSNHAKKSPNTST 2635
               H        E   +    + N +S+ S+D+KPL AR     SK  SNHA K    S 
Sbjct: 121  QQNHHKSSAAFIEPKPSVPAAKANSNSESSDDEKPLIARTSGCSSKGKSNHANKEGGDSC 180

Query: 2634 LSQKRRIPIPEDSDDEIPLSSKFQVKSNAGESINRSSNSGERKPLLSKYDQNGSASTE-- 2461
              ++  I   EDS+DE PLS +F  KS+ GES ++S +S E+KPL +K  QNGSAS +  
Sbjct: 181  SIRRPVIEESEDSEDEKPLSRRFPSKSSLGESTSKSYDSDEKKPLATKVQQNGSASRDGP 240

Query: 2460 -RKPSTNLKKRPGDGVKTTDESYLKKPKLSEAATPHKNKEASIKAEMREEDDE------- 2305
              K ++ L KR    VK+ ++S LKK KLS   T   NK+A++K E + EDD+       
Sbjct: 241  MNKSASLLNKRAPGEVKSLNQSSLKKAKLSSPITSISNKQAAVKPEPKAEDDDDNIPLSQ 300

Query: 2304 -----------------DHVPISHRMXXXXXXXXXXXXXKN-ITKPIXXXXXXXXXXXXX 2179
                             D+ PIS R+                 +  +             
Sbjct: 301  RGKKSQTAASKPKDEDDDNAPISQRIKKSPASVSKSSAPVKKASTVVSPSLKKVNKKSKK 360

Query: 2178 XXXXXXXXXXXXXXXXSGEGQKWTTLVHNGVIFPPPYKPHGVKMLYKGKPVDLTPEQEEV 1999
                            SGEGQKWTTLVHNGV+F PPYKPHGVKMLYK +P+ LTPEQEEV
Sbjct: 361  VIKKTAYTKSSKVPPGSGEGQKWTTLVHNGVMFLPPYKPHGVKMLYKXQPLTLTPEQEEV 420

Query: 1998 ATMYAVMLETDYMNKPKFKENFMADWRKILGKNHTIQSLEHCDFTPIYEWHXXXXXXXXX 1819
            ATM+AVML+TDYM KP+FKENF +DW+K+LGKNHT+Q+LE CDF PIYEWH         
Sbjct: 421  ATMFAVMLDTDYMTKPRFKENFFSDWKKMLGKNHTVQNLEDCDFGPIYEWHQQEKEKRKQ 480

Query: 1818 XXXXXXXXXXXXXXXXXXKYMWAIVNGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIR 1639
                              KYMWAIV+GVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIR
Sbjct: 481  MTTEEKKALKEERLQQEEKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIR 540

Query: 1638 PSDITINIGKDAPIPECPIPGESWKEIRHDNTVTWLAYWNDPINPKEFKYVFLAASSTLK 1459
            P DITINIGKDAPIPECPIPGE WKE+R+DNTVTWLA+WNDPIN KE KYVFLAASSTLK
Sbjct: 541  PRDITINIGKDAPIPECPIPGERWKEVRNDNTVTWLAFWNDPINQKECKYVFLAASSTLK 600

Query: 1458 GQSDKEKYEKARLLKDYILGIRAAYTKDFTS-KDPAKRQIAVATYLIDKLALRAGNEKDD 1282
            GQSDKEKYEKARLLKDYI GIRAAYTKDFT+ KDP K+QIAVATYLIDKLALRAGNEKDD
Sbjct: 601  GQSDKEKYEKARLLKDYIHGIRAAYTKDFTNNKDPMKKQIAVATYLIDKLALRAGNEKDD 660

Query: 1281 DEADTVGCCTLKVENVEPVPPNTLKFDFLGKDSIRYQNEVEVETAVFKAIQQFRSGKKGG 1102
            DEADTVGCCTLKVENVEPVPPN LK DF+GKDSIRYQNEV+VE AVFKAIQQFRSGK+G 
Sbjct: 661  DEADTVGCCTLKVENVEPVPPNILKIDFIGKDSIRYQNEVQVEPAVFKAIQQFRSGKEGC 720

Query: 1101 DDLFDRLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSRETRGGDVAEKVVVYQHA 922
             DLFDRLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLS+ET+GG VAEKV VYQHA
Sbjct: 721  ADLFDRLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSKETKGGKVAEKVGVYQHA 780

Query: 921  NKEVAIICNHQRTVSKSHSAQMLRLNEKIEELKGVVEELQTDLARAKKGKPPLKSADGKP 742
            NKEVAIICNHQRTVSKSHSAQM RLNEKI+ELK  +EEL+TDL+RAKKGKPP K ADG+P
Sbjct: 781  NKEVAIICNHQRTVSKSHSAQMSRLNEKIDELKTALEELKTDLSRAKKGKPPAKGADGEP 840

Query: 741  KRNLNPDALERKIAQTTAKIEKMERDKETKEDLKTVALGTSKINYLDPRITVAWCKRHEV 562
            KRNLNP++LERKIAQT AKIEKMERDK+TKEDLK VAL TSKI+YLDPRITVAWCKRHEV
Sbjct: 841  KRNLNPESLERKIAQTNAKIEKMERDKKTKEDLKAVALSTSKISYLDPRITVAWCKRHEV 900

Query: 561  PIEKIFNKSLLAKFAWAMDVDPGFRF 484
            PIEKIFNKSLLAKFAW+MDVDP FRF
Sbjct: 901  PIEKIFNKSLLAKFAWSMDVDPSFRF 926


>gb|EOY12189.1| DNA topoisomerase I alpha isoform 1 [Theobroma cacao]
            gi|508720293|gb|EOY12190.1| DNA topoisomerase I alpha
            isoform 1 [Theobroma cacao]
          Length = 904

 Score = 1087 bits (2810), Expect = 0.0
 Identities = 580/911 (63%), Positives = 661/911 (72%), Gaps = 18/911 (1%)
 Frame = -3

Query: 3162 MAVEACDKQKLXXXXXXXXEPLVFKRXXXXXXXXXXXS-EAKKSLSQKHDRQLGRPAPDV 2986
            MAVEA  K            P+VFKR           + E KK+ SQ+ D Q GR   DV
Sbjct: 1    MAVEAPAKHVYDFDDDDDDGPVVFKRNNTSSSKQNQLNSEVKKASSQRSDGQSGRQVSDV 60

Query: 2985 RSQNGQSTIVKKSKTVPLSKTPPVKYPLTSPKSSNTSGKALALKSPEVDSKPSTSVTDKS 2806
            RS NGQS+   K+K++  SK+PPVK P+ SPK+S +S KAL +KSP V+ K STS+ D+S
Sbjct: 61   RSPNGQSSNAPKNKSISSSKSPPVKSPILSPKASTSSTKALPVKSPVVNFKASTSLNDQS 120

Query: 2805 NSVKHQ-----IKDEKLSTEATGEPNEDSQDSEDDKPLSARLPAGLSKVNSNHAKKSPNT 2641
                 Q     +K+ +   + T EPN D  D +D  PLSARL     K  SN   K  +T
Sbjct: 121  KQALKQNMTTAVKEGRSPIKGTTEPNSDDDDDDDSLPLSARL-----KGISNQGNKGAST 175

Query: 2640 STLSQKRRIPIP--------EDSDDEIPLSSKFQVKSNAGESINRSSNSGERKPLLSKYD 2485
            S  +Q RR+ +P        ED DDE PLS++F VKSN G S +R  +  E+KPL SK  
Sbjct: 176  SAPAQSRRL-VPKTEVKVSAEDPDDEAPLSARFNVKSNTGTSSSRLHDCDEKKPLASKIQ 234

Query: 2484 QNGSA--STERKPSTNLKKRPGDGVKTTDESYLKKPKLSEAATPHKNKEASIKAEMREED 2311
            QNGS     ++  ST   KRP D   ++D S  KKPK S+A T  K K+ ++KAE  +ED
Sbjct: 235  QNGSIMKGKQQNSSTLSGKRPLDKGNSSDHSSAKKPKTSDAPTTMKTKQVTVKAEKADED 294

Query: 2310 DEDHVPISHRMXXXXXXXXXXXXXKN-ITKPIXXXXXXXXXXXXXXXXXXXXXXXXXXXX 2134
            D DH+PI+ RM             K   TK +                            
Sbjct: 295  D-DHMPIAQRMKKSTASNSKLSSMKQKTTKVVSSSFKKINKKSKKEMKSSKYIKSTKVPP 353

Query: 2133 XSGEGQK-WTTLVHNGVIFPPPYKPHGVKMLYKGKPVDLTPEQEEVATMYAVMLETDYMN 1957
             SG+GQK W+TLVHNGVIFP PY PHGVKMLY G+PVDLTPEQEEVATM+AVM +TDYM+
Sbjct: 354  SSGDGQKKWSTLVHNGVIFPSPYTPHGVKMLYDGRPVDLTPEQEEVATMFAVMKDTDYMS 413

Query: 1956 KPKFKENFMADWRKILGKNHTIQSLEHCDFTPIYEWHXXXXXXXXXXXXXXXXXXXXXXX 1777
            K +FK+NF  DW K+LGKNHTI+ L+ CDFTPIYEWH                       
Sbjct: 414  KTQFKKNFWEDWSKLLGKNHTIKDLDRCDFTPIYEWHLQEKEKKKQMSSEEKKALKEEKL 473

Query: 1776 XXXXKYMWAIVNGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIRPSDITINIGKDAPI 1597
                K+MWAIV+GVKEKVGNFRVEPPGLFRGRGEHPKMGKLK+RIRPSDITINIGKDAPI
Sbjct: 474  KQEEKFMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKRRIRPSDITINIGKDAPI 533

Query: 1596 PECPIPGESWKEIRHDNTVTWLAYWNDPINPKEFKYVFLAASSTLKGQSDKEKYEKARLL 1417
            PECPIPGE WK+I+HDNTVTWLA+WNDPINPKEFKYVFLAASS+LKGQSDKEKYEKAR+L
Sbjct: 534  PECPIPGERWKDIKHDNTVTWLAFWNDPINPKEFKYVFLAASSSLKGQSDKEKYEKARML 593

Query: 1416 KDYILGIRAAYTKDFTSKDPAKRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVEN 1237
            KDYI  IRAAYTKDFT+KD  KRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKV N
Sbjct: 594  KDYIKNIRAAYTKDFTTKDVMKRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVGN 653

Query: 1236 VEPVPPNTLKFDFLGKDSIRYQNEVEVETAVFKAIQQFRSGKKGGDDLFDRLDTSKLNAH 1057
            VE +PPN LKFDFLGKDSI+Y N VEVE  V+KAI QF++GK   DDLFD+LDTSKLNAH
Sbjct: 654  VECIPPNKLKFDFLGKDSIQYVNTVEVELPVYKAIGQFQTGKSKSDDLFDKLDTSKLNAH 713

Query: 1056 LKELMPGLTAKVFRTYNASITLDDMLSRETRGGDVAEKVVVYQHANKEVAIICNHQRTVS 877
            LKELMPGLTAKVFRTYNASITLD+ML++ET+ GDVAEKVVVYQ ANKEVAIICNHQR++S
Sbjct: 714  LKELMPGLTAKVFRTYNASITLDEMLNKETKDGDVAEKVVVYQRANKEVAIICNHQRSIS 773

Query: 876  KSHSAQMLRLNEKIEELKGVVEELQTDLARAKKGKPPLKSADGKPKRNLNPDALERKIAQ 697
            KSHSAQM RL EKI ELKGV++EL+ DL RAKKGKPPLK ADGK KRNL P A+++KI Q
Sbjct: 774  KSHSAQMSRLTEKITELKGVLKELKIDLDRAKKGKPPLKDADGKQKRNLTPQAIQKKIDQ 833

Query: 696  TTAKIEKMERDKETKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFA 517
            T AKIEKMERD +TKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFA
Sbjct: 834  TNAKIEKMERDMQTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFA 893

Query: 516  WAMDVDPGFRF 484
            WAMDVDP FRF
Sbjct: 894  WAMDVDPDFRF 904


>dbj|BAK32959.1| topoisomerase I [Ophiorrhiza plumbea]
          Length = 920

 Score = 1082 bits (2799), Expect = 0.0
 Identities = 578/920 (62%), Positives = 655/920 (71%), Gaps = 34/920 (3%)
 Frame = -3

Query: 3162 MAVEACDKQKLXXXXXXXXEPLVFKRXXXXXXXXXXXSEAKKSLSQKHDRQLGRPAPDVR 2983
            MAVEAC    L         P++FKR           SE KK   QKH  Q      DVR
Sbjct: 1    MAVEACTTPNLMEDMEDDEGPVIFKRSNPASKQNQANSEKKKLSLQKHVGQSAVHTSDVR 60

Query: 2982 SQNGQSTIVKKSKTVPLSKTPPVKYPLTSPKSSNTSGKALALKSPEVDSKPSTSVTDKSN 2803
              NG+S+  +K +  P ++TPPVK PL+SPK+SN+S KA  + SP  +SK S S T  + 
Sbjct: 61   PANGESSSAQKGRIQPSAETPPVKSPLSSPKASNSSAKASPITSPGANSKLSASATSTAK 120

Query: 2802 SVKHQIKD----EKLSTEATGEPNEDSQDSEDDKPLSARLPAGLSKVNSNHAKKSPNTST 2635
               H        E   +    + N +S+ S+D+KPL AR     SK  SNHA K    S 
Sbjct: 121  QQNHHKSSAAFIEPKPSVPAAKANSNSESSDDEKPLIARTSGCSSKGKSNHANKEGGDSC 180

Query: 2634 LSQKRRIPIPEDSDDEIPLSSKFQVKSNAGESINRSSNSGERKPLLSKYDQNGSASTE-- 2461
              ++  I   EDS+DE PLS +F  KS+ GES ++S +S E+KPL +K   NGSAS +  
Sbjct: 181  SIRRPVIEESEDSEDEKPLSRRFPSKSSLGESTSKSYDSDEKKPLAAKVQPNGSASRDGP 240

Query: 2460 --RKPSTNLKKRPGDGVKTTDESYLKKPKLSEAATPHKNKEASIKAEMREEDDE------ 2305
              +  S + K+ PG+ VK+ ++S LKKPKLS   T   NK+A++K E + EDD+      
Sbjct: 241  MNKSASLSNKRAPGE-VKSLNQSSLKKPKLSSPITSISNKQAAVKPEPKAEDDDDNIPLS 299

Query: 2304 ------------------DHVPISHRMXXXXXXXXXXXXXKN-ITKPIXXXXXXXXXXXX 2182
                              D+ PIS R+                 +  +            
Sbjct: 300  QRGKKSQTAASKPKDEDDDNAPISQRIKKSPASVSKSSAPVKKASTVVSPSLKKVNKKSK 359

Query: 2181 XXXXXXXXXXXXXXXXXSGEGQKWTTLVHNGVIFPPPYKPHGVKMLYKGKPVDLTPEQEE 2002
                             SGEGQKWTTLVHNGVIFPPPYKPHGVKMLYK +P+ LTPEQEE
Sbjct: 360  KVIKKTAYTKSSKVPPGSGEGQKWTTLVHNGVIFPPPYKPHGVKMLYKRQPITLTPEQEE 419

Query: 2001 VATMYAVMLETDYMNKPKFKENFMADWRKILGKNHTIQSLEHCDFTPIYEWHXXXXXXXX 1822
            VATM+AVML+TDYMNKP+FKENF +DW+K+LGKNHTIQ+LE CDF PIYEWH        
Sbjct: 420  VATMFAVMLDTDYMNKPRFKENFFSDWKKMLGKNHTIQNLEDCDFGPIYEWHQQEKEKKK 479

Query: 1821 XXXXXXXXXXXXXXXXXXXKYMWAIVNGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRI 1642
                               KYMW IV+GVKEKVGNFRVEPPGLFRGRGEHPK+GKLKKRI
Sbjct: 480  QMTTEEKKALKEERLQQEEKYMWVIVDGVKEKVGNFRVEPPGLFRGRGEHPKVGKLKKRI 539

Query: 1641 RPSDITINIGKDAPIPECPIPGESWKEIRHDNTVTWLAYWNDPINPKEFKYVFLAASSTL 1462
            RP DITINIGKDAPIPECPIPGE WKE+R+DNTVTWLAYWNDPIN KE KYVFL ASSTL
Sbjct: 540  RPRDITINIGKDAPIPECPIPGERWKEVRNDNTVTWLAYWNDPINQKERKYVFLGASSTL 599

Query: 1461 KGQSDKEKYEKARLLKDYILGIRAAYTKDFTS-KDPAKRQIAVATYLIDKLALRAGNEKD 1285
            KGQSDKEKYEKARLLKDYI GIRAAYTKDFT+ KDP K+QIAVATYLIDKLALRAGNEKD
Sbjct: 600  KGQSDKEKYEKARLLKDYIHGIRAAYTKDFTNNKDPMKKQIAVATYLIDKLALRAGNEKD 659

Query: 1284 DDEADTVGCCTLKVENVEPVPPNTLKFDFLGKDSIRYQNEVEVETAVFKAIQQFRSGKKG 1105
            DDEADTVGCCTLKVENVEPVPPN LK DF+GKDSIRYQNEV+VE AVFKAIQQFRSGK+G
Sbjct: 660  DDEADTVGCCTLKVENVEPVPPNILKIDFIGKDSIRYQNEVQVEPAVFKAIQQFRSGKEG 719

Query: 1104 GDDLFDRLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSRETRGGDVAEKVVVYQH 925
              DLFDRLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLS+ET+GG VAEKV VYQH
Sbjct: 720  SADLFDRLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSKETKGGKVAEKVGVYQH 779

Query: 924  ANKEVAIICNHQRTVSKSHSAQMLRLNEKIEELKGVVEELQTDLARAKKGKPPLKSADGK 745
            ANKEVAIICNHQRTVSKSHSAQM RLNEKI+ELK  +EEL+TDL+RAKKGKPP K ADG+
Sbjct: 780  ANKEVAIICNHQRTVSKSHSAQMSRLNEKIDELKTALEELKTDLSRAKKGKPPSKGADGE 839

Query: 744  PKRNLNPDALERKIAQTTAKIEKMERDKETKEDLKTVALGTSKINYLDPRITVAWCKRHE 565
            PKRNLNP+ALERKIAQT AKIEKME DK+TKEDLK VAL TSKI+YL PRITVAWCKRHE
Sbjct: 840  PKRNLNPEALERKIAQTNAKIEKMEGDKKTKEDLKAVALSTSKISYLGPRITVAWCKRHE 899

Query: 564  VPIEKIFNKSLLAKFAWAMD 505
            VPIEK+FNKSLLAKFAWAM+
Sbjct: 900  VPIEKMFNKSLLAKFAWAMN 919


>dbj|BAK32963.1| topoisomerase I [Ophiorrhiza sp. 35]
          Length = 920

 Score = 1082 bits (2798), Expect = 0.0
 Identities = 576/920 (62%), Positives = 657/920 (71%), Gaps = 34/920 (3%)
 Frame = -3

Query: 3162 MAVEACDKQKLXXXXXXXXEPLVFKRXXXXXXXXXXXSEAKKSLSQKHDRQLGRPAPDVR 2983
            MAVEAC    L         P++FKR           SE KK   QKH  Q      DVR
Sbjct: 1    MAVEACTTTNLMEDMEDDEGPVIFKRSNPASKQNQANSEKKKLSLQKHVGQSAVHTSDVR 60

Query: 2982 SQNGQSTIVKKSKTVPLSKTPPVKYPLTSPKSSNTSGKALALKSPEVDSKPSTSVTDKSN 2803
              NG+S+  +K +  P ++TPPVK PL+SPK+SN+S KA  + SP  +SK S S T  + 
Sbjct: 61   PANGESSSAQKGRIQPSAETPPVKSPLSSPKASNSSAKASPITSPGANSKLSASATSTAK 120

Query: 2802 SVKHQIKD----EKLSTEATGEPNEDSQDSEDDKPLSARLPAGLSKVNSNHAKKSPNTST 2635
               H        E   +    + N +S+ S+D+KPL AR     SK  SNHA K    S 
Sbjct: 121  QQNHHKSSAAFIEPKPSVPPAKANSNSESSDDEKPLIARTSGCSSKGKSNHANKEGGDSC 180

Query: 2634 LSQKRRIPIPEDSDDEIPLSSKFQVKSNAGESINRSSNSGERKPLLSKYDQNGSASTE-- 2461
              ++  +   EDS+DE PLS +F  KS+ GES ++S +S E+KPL +K  QNGSAS +  
Sbjct: 181  SIRRPVVEESEDSEDEKPLSRRFPSKSSLGESTSKSYDSDEKKPLAAKVQQNGSASRDGP 240

Query: 2460 --RKPSTNLKKRPGDGVKTTDESYLKKPKLSEAATPHKNKEASIKAEMREEDDE------ 2305
              +  S + K+ PG+ VK+ ++S LKKPKLS   T   NK+A++K E + EDD+      
Sbjct: 241  MNKSASLSNKRAPGE-VKSLNQSSLKKPKLSSPITSISNKQAAVKPEPKAEDDDDNIPLS 299

Query: 2304 ------------------DHVPISHRMXXXXXXXXXXXXXKN-ITKPIXXXXXXXXXXXX 2182
                              D+ PIS R+                 +  +            
Sbjct: 300  QRGKKSQTAASKPKDEDDDNAPISQRIKKSPASVSKSSAPVKKASTVVSPSLKKVNKKSK 359

Query: 2181 XXXXXXXXXXXXXXXXXSGEGQKWTTLVHNGVIFPPPYKPHGVKMLYKGKPVDLTPEQEE 2002
                             SGEGQKWTTLVHNGVIFPPPYKPHGVKMLYK +P+ LTPEQEE
Sbjct: 360  KVIKKTAYTKSSKVPPGSGEGQKWTTLVHNGVIFPPPYKPHGVKMLYKRQPLTLTPEQEE 419

Query: 2001 VATMYAVMLETDYMNKPKFKENFMADWRKILGKNHTIQSLEHCDFTPIYEWHXXXXXXXX 1822
            VATM+AVML+TDYMNKP+FKENF +DW+K+LGKNHTIQ+LE CDF PIYEWH        
Sbjct: 420  VATMFAVMLDTDYMNKPRFKENFFSDWKKMLGKNHTIQNLEDCDFGPIYEWHQQEREKKK 479

Query: 1821 XXXXXXXXXXXXXXXXXXXKYMWAIVNGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRI 1642
                               KYMWAIV+GVKEKVGNFRVEPPGLFRGRGEHPK+GKLKKRI
Sbjct: 480  QMTTEEKKALKDERLQQEEKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKVGKLKKRI 539

Query: 1641 RPSDITINIGKDAPIPECPIPGESWKEIRHDNTVTWLAYWNDPINPKEFKYVFLAASSTL 1462
             P DITINIGKDAPIPECPIPGE WKE+R+DNTVTWLAYWNDP+N KE KYVFLA SSTL
Sbjct: 540  HPRDITINIGKDAPIPECPIPGERWKEVRNDNTVTWLAYWNDPVNLKECKYVFLAPSSTL 599

Query: 1461 KGQSDKEKYEKARLLKDYILGIRAAYTKDFTS-KDPAKRQIAVATYLIDKLALRAGNEKD 1285
            KGQSDKEKYEKARLLKDYI GIRAAYTKDFT+ KDP K+QIAVATYLIDKLALRAGNEKD
Sbjct: 600  KGQSDKEKYEKARLLKDYIHGIRAAYTKDFTNNKDPMKKQIAVATYLIDKLALRAGNEKD 659

Query: 1284 DDEADTVGCCTLKVENVEPVPPNTLKFDFLGKDSIRYQNEVEVETAVFKAIQQFRSGKKG 1105
            DDEADTVGCCTL+VENVEPVPPN LK DF+GKDSIRYQNEV+VE AVFKAIQQFRSGK+G
Sbjct: 660  DDEADTVGCCTLRVENVEPVPPNILKIDFIGKDSIRYQNEVQVEPAVFKAIQQFRSGKEG 719

Query: 1104 GDDLFDRLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSRETRGGDVAEKVVVYQH 925
             +DLFDRLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLS+ET+GG VAEKV VYQH
Sbjct: 720  SEDLFDRLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSKETKGGKVAEKVGVYQH 779

Query: 924  ANKEVAIICNHQRTVSKSHSAQMLRLNEKIEELKGVVEELQTDLARAKKGKPPLKSADGK 745
            ANKEVAIICNHQRTVSKSHSAQM RLNEKI+ELK  +EEL+TDL+RAKKGKPP K  DG+
Sbjct: 780  ANKEVAIICNHQRTVSKSHSAQMSRLNEKIDELKTALEELKTDLSRAKKGKPPSKGDDGE 839

Query: 744  PKRNLNPDALERKIAQTTAKIEKMERDKETKEDLKTVALGTSKINYLDPRITVAWCKRHE 565
            PKRNLNP+ALERKIAQT AKIEKMERDK+TKEDLK VAL TSKI+YLDPRITVAWCKR E
Sbjct: 840  PKRNLNPEALERKIAQTNAKIEKMERDKKTKEDLKAVALSTSKISYLDPRITVAWCKRQE 899

Query: 564  VPIEKIFNKSLLAKFAWAMD 505
            VPIEK+FNKSLLAKFAWAM+
Sbjct: 900  VPIEKMFNKSLLAKFAWAMN 919


>ref|XP_006364175.1| PREDICTED: LOW QUALITY PROTEIN: DNA topoisomerase 1-like [Solanum
            tuberosum]
          Length = 905

 Score = 1074 bits (2777), Expect = 0.0
 Identities = 573/918 (62%), Positives = 647/918 (70%), Gaps = 25/918 (2%)
 Frame = -3

Query: 3162 MAVEACDKQKLXXXXXXXXE-PLVFKRXXXXXXXXXXXSEAKKSLSQKHDRQLGRPAPDV 2986
            MAVEA  K  L        + PLVFKR                S SQK D + GR  PDV
Sbjct: 1    MAVEAFAKTNLMEDIDDDDDMPLVFKRSSTTSKQ-----NQSNSSSQKQDGRSGRQVPDV 55

Query: 2985 RSQNGQSTIVKKSKTVPLSKTPPVKYPLTSPKSSNTSGKAL------------------- 2863
            RS NGQS+   K KT   SK  P   PLTSPK++  S +                     
Sbjct: 56   RSPNGQSSSTHKVKTAASSKASPAVSPLTSPKAAPLSSRTSPAPNFRTSPAPNSRTPPAP 115

Query: 2862 -ALKSPEVDSKPSTSVTDKSNSVKHQI----KDEKLSTEATGEPNEDSQDSEDDKPLSAR 2698
             +  SP  +S+PS+S  +++ +V  Q     K+ K + E   EPN++++DSEDDKPLSAR
Sbjct: 116  NSRTSPAPNSRPSSSAGNQAKNVNQQSNIAPKESKQAIEPKSEPNDEAEDSEDDKPLSAR 175

Query: 2697 LPAGLSKVNSNHAKKSPNTSTLSQKRRIPIPEDSDDEIPLSSKFQVKSNAGESINRSSNS 2518
            +P+GLSK NS HA     TST  QK R P  EDSDDEIPL+S+FQ+KS+AG S ++ S+S
Sbjct: 176  VPSGLSKSNSIHANNVLGTSTSVQKSRPPKKEDSDDEIPLASRFQMKSSAGASTSKFSSS 235

Query: 2517 GERKPLLSKYDQNGSASTERKPSTNLKKRPGDGVKTTDESYLKKPKLSEAATPHKNKEAS 2338
             E KP   K  QNG  S     +T L KRP   V       LK                S
Sbjct: 236  EEVKP---KIRQNGLPS-----ATVLSKRPPGEVSLLLRLQLKSLDFLMHLHLFLVSNXS 287

Query: 2337 IKAEMREEDDEDHVPISHRMXXXXXXXXXXXXXKNITKPIXXXXXXXXXXXXXXXXXXXX 2158
            +K E + EDD+D VP+S R+              +  K                      
Sbjct: 288  VKTEKKTEDDDDEVPLSQRIKKAVASASASASKVSSVKKATKVVSSSMKKTKKKLKKPKY 347

Query: 2157 XXXXXXXXXSGEGQKWTTLVHNGVIFPPPYKPHGVKMLYKGKPVDLTPEQEEVATMYAVM 1978
                     SG+GQKWTTL HNGVIFPPPYKPHGVKMLYKGKPVDLTPEQEEVATMYAVM
Sbjct: 348  SKSSKLQPSSGDGQKWTTLEHNGVIFPPPYKPHGVKMLYKGKPVDLTPEQEEVATMYAVM 407

Query: 1977 LETDYMNKPKFKENFMADWRKILGKNHTIQSLEHCDFTPIYEWHXXXXXXXXXXXXXXXX 1798
            L+T+Y+ K +FKENFM DWRKILGKNH IQ LE C+FTPIYEWH                
Sbjct: 408  LDTEYLTKQQFKENFMNDWRKILGKNHVIQKLEECNFTPIYEWHQSEKEKKKQMSSEEKK 467

Query: 1797 XXXXXXXXXXXKYMWAIVNGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIRPSDITIN 1618
                       KYMWAIV+GVKEKVGNFRVEPPGLFRGRGEHPKMGKLK+RIRP+DITIN
Sbjct: 468  ALREEKLKQEEKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKRRIRPNDITIN 527

Query: 1617 IGKDAPIPECPIPGESWKEIRHDNTVTWLAYWNDPINPKEFKYVFLAASSTLKGQSDKEK 1438
            IGK  P+PECPIPG+ WKE+RHDNTVTWLA+WNDPINP+EFKYVFLAASS+LKGQSDKEK
Sbjct: 528  IGKGVPVPECPIPGQRWKEVRHDNTVTWLAFWNDPINPREFKYVFLAASSSLKGQSDKEK 587

Query: 1437 YEKARLLKDYILGIRAAYTKDFTSKDPAKRQIAVATYLIDKLALRAGNEKDDDEADTVGC 1258
            YEKAR LKDYI GIR+AYTKDFTSKDP KRQIAVATYLIDKLALRAGNEKDDDEADTVGC
Sbjct: 588  YEKARRLKDYIEGIRSAYTKDFTSKDPVKRQIAVATYLIDKLALRAGNEKDDDEADTVGC 647

Query: 1257 CTLKVENVEPVPPNTLKFDFLGKDSIRYQNEVEVETAVFKAIQQFRSGKKGGDDLFDRLD 1078
            CTLKVENVEPVPPN LKFDFLGKDSIRYQNEV V   VFKAIQQFRSGKKGGDDLFD+LD
Sbjct: 648  CTLKVENVEPVPPNILKFDFLGKDSIRYQNEVAVYEPVFKAIQQFRSGKKGGDDLFDKLD 707

Query: 1077 TSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSRETRGGDVAEKVVVYQHANKEVAIIC 898
            TSKLNAHLKELMPGLTAKVFRTYNAS TL+  L++ T+GG++A+KV VY  ANKEVAIIC
Sbjct: 708  TSKLNAHLKELMPGLTAKVFRTYNASFTLEQQLTKLTQGGELADKVAVYNVANKEVAIIC 767

Query: 897  NHQRTVSKSHSAQMLRLNEKIEELKGVVEELQTDLARAKKGKPPLKSADGKPKRNLNPDA 718
            NHQRTVSKSHS Q+ RLNEKI+ELK ++EE + DLARAKKGKPP+K ADGK KRNL P+A
Sbjct: 768  NHQRTVSKSHSVQISRLNEKIDELKAILEEFKVDLARAKKGKPPVKGADGKAKRNLTPEA 827

Query: 717  LERKIAQTTAKIEKMERDKETKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNK 538
            L++KI QT  KI+ +ER  ETKE+LKTVALGTSKINYLDPRITVAWCKRHEVPIEK+FNK
Sbjct: 828  LQKKIDQTNVKIDNIERQIETKEELKTVALGTSKINYLDPRITVAWCKRHEVPIEKMFNK 887

Query: 537  SLLAKFAWAMDVDPGFRF 484
            SLLAKFAWAMDV+P F F
Sbjct: 888  SLLAKFAWAMDVEPSFTF 905


>dbj|BAK32957.1| topoisomerase I [Ophiorrhiza harrisiana]
          Length = 920

 Score = 1070 bits (2767), Expect = 0.0
 Identities = 572/920 (62%), Positives = 654/920 (71%), Gaps = 34/920 (3%)
 Frame = -3

Query: 3162 MAVEACDKQKLXXXXXXXXEPLVFKRXXXXXXXXXXXSEAKKSLSQKHDRQLGRPAPDVR 2983
            MAVEAC    L         P++FKR           SE KK   QKH  Q      DVR
Sbjct: 1    MAVEACTTTNLMEDMEDDEGPVIFKRSNPASKQNQANSEKKKLSLQKHVGQSAVHTSDVR 60

Query: 2982 SQNGQSTIVKKSKTVPLSKTPPVKYPLTSPKSSNTSGKALALKSPEVDSKPSTSVTDKSN 2803
              NG+S+  +K +  P ++TPPVK PL+SPK+SN+S KA  + SP  +SK S S T  + 
Sbjct: 61   PANGESSSAQKGRIQPSAETPPVKSPLSSPKASNSSAKASPITSPGANSKLSASATSTAK 120

Query: 2802 SVKHQIKD----EKLSTEATGEPNEDSQDSEDDKPLSARLPAGLSKVNSNHAKKSPNTST 2635
               H        E   +    + N +S+ S+D+KPL AR     SK  SNHA K    S 
Sbjct: 121  QQNHHKSSAAFIEPKPSVPPAKANSNSESSDDEKPLIARTSGCSSKGKSNHANKEGGDSC 180

Query: 2634 LSQKRRIPIPEDSDDEIPLSSKFQVKSNAGESINRSSNSGERKPLLSKYDQNGSASTE-- 2461
              ++  +   EDS+DE PLS +F  KS+ GES ++S +S E+KPL +K  QNGSAS +  
Sbjct: 181  SIRRPVVEESEDSEDEKPLSRRFPSKSSLGESTSKSYDSDEKKPLAAKVQQNGSASRDGP 240

Query: 2460 --RKPSTNLKKRPGDGVKTTDESYLKKPKLSEAATPHKNKEASIKAEMREEDDE------ 2305
              +  S + K+ PG+ VK+ ++S LKKPKLS   T   NK+A++K E + EDD+      
Sbjct: 241  MNKSASLSNKRAPGE-VKSLNQSSLKKPKLSSPITSISNKQAAVKPEPKAEDDDDNIPLS 299

Query: 2304 ------------------DHVPISHRMXXXXXXXXXXXXXKN-ITKPIXXXXXXXXXXXX 2182
                              D+ PIS R+                 +  +            
Sbjct: 300  QRGKKSQTAASKPKDEDDDNAPISQRIKKSPASVSKSSAPVKKASTVVSPSLKKVNKKSK 359

Query: 2181 XXXXXXXXXXXXXXXXXSGEGQKWTTLVHNGVIFPPPYKPHGVKMLYKGKPVDLTPEQEE 2002
                             SGEGQKWTTLVHNGV+F PPYKPHGVKMLYK +P+ LTPEQEE
Sbjct: 360  KVIKKTAYTKSSKVPPGSGEGQKWTTLVHNGVMFLPPYKPHGVKMLYKQQPLTLTPEQEE 419

Query: 2001 VATMYAVMLETDYMNKPKFKENFMADWRKILGKNHTIQSLEHCDFTPIYEWHXXXXXXXX 1822
            VATM+AVML+TDYM KP+FKENF +DW+K+LGKNHT+Q+LE CDF PIYEWH        
Sbjct: 420  VATMFAVMLDTDYMTKPRFKENFFSDWKKMLGKNHTVQNLEDCDFGPIYEWHQQEKEKRK 479

Query: 1821 XXXXXXXXXXXXXXXXXXXKYMWAIVNGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRI 1642
                               KYM AIV+GVKEKVGNFRVEPPGLFRGRGEHPK+GKLKKRI
Sbjct: 480  QMTTEEKKALKEERLQQEEKYMRAIVDGVKEKVGNFRVEPPGLFRGRGEHPKVGKLKKRI 539

Query: 1641 RPSDITINIGKDAPIPECPIPGESWKEIRHDNTVTWLAYWNDPINPKEFKYVFLAASSTL 1462
             P DITINIGKDAPIPECPIPGE WKE+R+DNTVTWLAYWNDP+N KE KYVFLA SSTL
Sbjct: 540  HPRDITINIGKDAPIPECPIPGERWKEVRNDNTVTWLAYWNDPVNLKECKYVFLAPSSTL 599

Query: 1461 KGQSDKEKYEKARLLKDYILGIRAAYTKDFTS-KDPAKRQIAVATYLIDKLALRAGNEKD 1285
            KGQSDKEKYEKARLLKDYI GIRAAYTKDFT+ KDP K+QIAVATYLIDKLALRAGNEKD
Sbjct: 600  KGQSDKEKYEKARLLKDYIHGIRAAYTKDFTNNKDPMKKQIAVATYLIDKLALRAGNEKD 659

Query: 1284 DDEADTVGCCTLKVENVEPVPPNTLKFDFLGKDSIRYQNEVEVETAVFKAIQQFRSGKKG 1105
            DDEADTVGCCTLKVENVEPVPPN LK DF+GKDSIRYQNEV+VE AVFKAIQQFRSGK+G
Sbjct: 660  DDEADTVGCCTLKVENVEPVPPNILKIDFIGKDSIRYQNEVQVEPAVFKAIQQFRSGKEG 719

Query: 1104 GDDLFDRLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSRETRGGDVAEKVVVYQH 925
             +DLFDRLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLS+ET+GG VAEKV VYQH
Sbjct: 720  SEDLFDRLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSKETKGGKVAEKVGVYQH 779

Query: 924  ANKEVAIICNHQRTVSKSHSAQMLRLNEKIEELKGVVEELQTDLARAKKGKPPLKSADGK 745
            ANKEVAIICNHQRTVSKSHSAQM RLNEKI+ELK  +EEL+TDL+RAKKGKPP K  DG+
Sbjct: 780  ANKEVAIICNHQRTVSKSHSAQMSRLNEKIDELKTALEELKTDLSRAKKGKPPSKGDDGE 839

Query: 744  PKRNLNPDALERKIAQTTAKIEKMERDKETKEDLKTVALGTSKINYLDPRITVAWCKRHE 565
            PKRNLNP+ALERKIAQT AKIEKMERDK+TKEDLK VAL TSKI+YLDPRITVAWCKR E
Sbjct: 840  PKRNLNPEALERKIAQTNAKIEKMERDKKTKEDLKAVALSTSKISYLDPRITVAWCKRQE 899

Query: 564  VPIEKIFNKSLLAKFAWAMD 505
            VPIEK+FNKSLLAKFAWAM+
Sbjct: 900  VPIEKMFNKSLLAKFAWAMN 919


>gb|AAD08711.1| topoisomerase I [Nicotiana tabacum] gi|14626487|gb|AAK69776.1|
            topoisomerase I [Nicotiana tabacum]
          Length = 852

 Score = 1038 bits (2684), Expect = 0.0
 Identities = 561/874 (64%), Positives = 627/874 (71%), Gaps = 6/874 (0%)
 Frame = -3

Query: 3162 MAVEACDKQKLXXXXXXXXE--PLVFKRXXXXXXXXXXXSEAKKSLSQKHDRQLGRPAPD 2989
            MAVEA  K KL        +  PLVFKR                S SQK D + GR A D
Sbjct: 1    MAVEAFSKTKLMAEVDDDDDDMPLVFKRSSTTSKQ-----NQSNSSSQKQDGRSGRQASD 55

Query: 2988 VRSQNGQSTIVKKSKTVPLSKTPPVKYPLTSPKSSNTSGKALALKSPEVDSKPSTSVTDK 2809
            VRS NGQS+  +K K    SK      P TSPK+S +SG+     SP  +S+PS S  ++
Sbjct: 56   VRSPNGQSSSAEKVKAGTSSKASRAVSPFTSPKASPSSGRT----SPAPNSRPSASAGNQ 111

Query: 2808 SNSVKHQIK----DEKLSTEATGEPNEDSQDSEDDKPLSARLPAGLSKVNSNHAKKSPNT 2641
            +  V  Q K    + K + E   EPN++++DSEDDKPLSARL +GLSK NS+HA K   T
Sbjct: 112  AKDVNQQSKIVPNEPKQAVEPKSEPNDEAEDSEDDKPLSARLSSGLSKSNSSHANKVLGT 171

Query: 2640 STLSQKRRIPIPEDSDDEIPLSSKFQVKSNAGESINRSSNSGERKPLLSKYDQNGSASTE 2461
            S   QK R P  EDSDDEIPL+S+FQ+KSNAG S ++SSNS E KP   K  QNG  ST 
Sbjct: 172  SASVQKSRPPKKEDSDDEIPLASRFQLKSNAGASTSKSSNSEEVKP---KIRQNGLPST- 227

Query: 2460 RKPSTNLKKRPGDGVKTTDESYLKKPKLSEAATPHKNKEASIKAEMREEDDEDHVPISHR 2281
                T L KRP   V       LK           +  EAS+K E + EDD+D VPIS R
Sbjct: 228  ----TVLSKRPPGDVSLLLRLQLKSLGFLMHLHLFRVSEASVKPEKKTEDDDDDVPISQR 283

Query: 2280 MXXXXXXXXXXXXXKNITKPIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSGEGQKWTTL 2101
            +             K  TK +                              GEGQKWTTL
Sbjct: 284  IKKSVASASKLSSAKKATKVVSSSMKTKKKLKKSKYSKSSKLQPSS-----GEGQKWTTL 338

Query: 2100 VHNGVIFPPPYKPHGVKMLYKGKPVDLTPEQEEVATMYAVMLETDYMNKPKFKENFMADW 1921
            VHNGVIFPPPYKPHGVKMLYKGKPVDLTPEQEEVATMYAVML+TDYM+K +FKENFM DW
Sbjct: 339  VHNGVIFPPPYKPHGVKMLYKGKPVDLTPEQEEVATMYAVMLDTDYMSKLQFKENFMNDW 398

Query: 1920 RKILGKNHTIQSLEHCDFTPIYEWHXXXXXXXXXXXXXXXXXXXXXXXXXXXKYMWAIVN 1741
            RKILGKNH IQ+L+ CDFTPIYE                             KYMWAIV+
Sbjct: 399  RKILGKNHVIQNLDDCDFTPIYERPSSEKEKKKQMSTKRKRPLREEKLKQEEKYMWAIVD 458

Query: 1740 GVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIRPSDITINIGKDAPIPECPIPGESWKE 1561
            GVKEKVGNFRVEPPGLFRGRGEHPKMGKLK+RIRP+DITINIGK APIPECPIPGE WKE
Sbjct: 459  GVKEKVGNFRVEPPGLFRGRGEHPKMGKLKRRIRPNDITINIGKGAPIPECPIPGERWKE 518

Query: 1560 IRHDNTVTWLAYWNDPINPKEFKYVFLAASSTLKGQSDKEKYEKARLLKDYILGIRAAYT 1381
            +RHDNTVTWLA+WNDPINP+EFKYVFLAASS+LKGQSDKEKYEKAR LKDYI GIR+AYT
Sbjct: 519  VRHDNTVTWLAFWNDPINPREFKYVFLAASSSLKGQSDKEKYEKARRLKDYIEGIRSAYT 578

Query: 1380 KDFTSKDPAKRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVEPVPPNTLKFD 1201
            KDFTSKDP KRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVEPVPPN LKFD
Sbjct: 579  KDFTSKDPVKRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVEPVPPNILKFD 638

Query: 1200 FLGKDSIRYQNEVEVETAVFKAIQQFRSGKKGGDDLFDRLDTSKLNAHLKELMPGLTAKV 1021
            FLGKDSIRYQNEV V   VFKAIQ FRSGKKGGDDLFD+LDTSKLNAHLKELMPGLTAKV
Sbjct: 639  FLGKDSIRYQNEVAVYKPVFKAIQLFRSGKKGGDDLFDKLDTSKLNAHLKELMPGLTAKV 698

Query: 1020 FRTYNASITLDDMLSRETRGGDVAEKVVVYQHANKEVAIICNHQRTVSKSHSAQMLRLNE 841
            FRTYNAS+TL+  L++ T+GG++AEKV VY  ANKEVAIICNHQR+VSKSHS Q+ +LNE
Sbjct: 699  FRTYNASVTLEQQLTKLTQGGELAEKVAVYNLANKEVAIICNHQRSVSKSHSVQISKLNE 758

Query: 840  KIEELKGVVEELQTDLARAKKGKPPLKSADGKPKRNLNPDALERKIAQTTAKIEKMERDK 661
            KI+ELK ++EE + DLARAKKGKPPLK ADGK KRNL P+AL++KI QT  KIE +E+  
Sbjct: 759  KIDELKALLEEFKVDLARAKKGKPPLKGADGKAKRNLAPEALQKKIDQTNVKIENIEKQI 818

Query: 660  ETKEDLKTVALGTSKINYLDPRITVAWCKRHEVP 559
            ETKE+LKTVALGTSKINYLDPRITVAWC+RH  P
Sbjct: 819  ETKEELKTVALGTSKINYLDPRITVAWCERHRFP 852


>ref|XP_004149585.1| PREDICTED: DNA topoisomerase 1-like [Cucumis sativus]
            gi|449503189|ref|XP_004161878.1| PREDICTED: DNA
            topoisomerase 1-like [Cucumis sativus]
          Length = 889

 Score = 1025 bits (2649), Expect = 0.0
 Identities = 553/901 (61%), Positives = 645/901 (71%), Gaps = 8/901 (0%)
 Frame = -3

Query: 3162 MAVEACDKQKLXXXXXXXXEPLVFKRXXXXXXXXXXXSEAKKSLSQKHDRQLGRPAPDVR 2983
            MAVE   K  +         P+VFKR            E K S +Q+  +  GR   D+ 
Sbjct: 1    MAVETFGKAPMFDDDDEDNMPIVFKRTSASRQNQLDS-EIKHSQAQRLSKLPGRQGSDLC 59

Query: 2982 SQNGQSTIVKKSKTVPLSKTPPVKYPLTSPKSSNTSGKALAL-KSPEVDSKPSTSVTDKS 2806
            S NGQS+  +K  T  L KT P++  + S K+S +S     L KS     K S S+  + 
Sbjct: 60   STNGQSSNNQKRMT-SLPKTSPMRSEIGSQKASRSSPIPEPLTKSLGTSLKASHSMDSRP 118

Query: 2805 NS-VKHQIKDEKLSTEATGEPNEDSQDSEDDKPLSARLPAGLSKVNSNHAKKSPNTSTLS 2629
             S V   +K+E +S      P++++ DSEDDKPLS RL     K N N   K    ST+ 
Sbjct: 119  KSLVNAVVKEENVSIN----PSQENSDSEDDKPLSIRL-----KGNPNQPNKGL-VSTVP 168

Query: 2628 QKRRIPIPEDSDDEIPLSSKFQVKSNAGESINRSSNSGERKPLLSKYDQNGSASTER--K 2455
            + +      DSDDE+PLSSKFQ+K  +G   ++     E+KPL+ K  QNGS S ++  K
Sbjct: 169  KNKVKKSLADSDDEVPLSSKFQMKHASGVLGSKQHGFDEKKPLVPKVHQNGSTSRDKLQK 228

Query: 2454 PSTNLKKRP--GDGVKTTDESYLKKPKLSEAATPHKNKEASIKAEMREEDDEDHVPISHR 2281
            P+    KRP   +   +  +   KKPKL+++++P  +K  S+KA+   +DD+D +PIS R
Sbjct: 229  PAVLSSKRPLPNEDSHSPSQFPTKKPKLTDSSSPLNSKLVSLKAKQEVDDDDDDIPISQR 288

Query: 2280 MXXXXXXXXXXXXXK-NITKPIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSGEGQK-WT 2107
            M             K  I+K +                             +G+GQK WT
Sbjct: 289  MKKVSATVNKSSSSKPTISKVVSSSIKKTFKKSKKPVKKSKYVKSTKLLPSAGDGQKKWT 348

Query: 2106 TLVHNGVIFPPPYKPHGVKMLYKGKPVDLTPEQEEVATMYAVMLETDYMNKPKFKENFMA 1927
            TLVHNGVIFPPPY+ HGVKMLYKGKPVDLTP QEEVATM+AVM +TDYM KPKFKENF  
Sbjct: 349  TLVHNGVIFPPPYQTHGVKMLYKGKPVDLTPPQEEVATMFAVMKDTDYMLKPKFKENFWN 408

Query: 1926 DWRKILGKNHTIQSLEHCDFTPIYEWHXXXXXXXXXXXXXXXXXXXXXXXXXXXKYMWAI 1747
            DWRK+LGKNH IQ+L+ CDFTPIY+W+                           KYMWAI
Sbjct: 409  DWRKLLGKNHVIQNLDDCDFTPIYDWYQMEKEKKKQMTTEEKKAVKEEKLKQEEKYMWAI 468

Query: 1746 VNGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIRPSDITINIGKDAPIPECPIPGESW 1567
            ++GVKEKVGNFRVEPPGLFRGRGEHPKMGKLK+RI PSDITINIGK APIPECPIPGE W
Sbjct: 469  LDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKRRICPSDITINIGKGAPIPECPIPGERW 528

Query: 1566 KEIRHDNTVTWLAYWNDPINPKEFKYVFLAASSTLKGQSDKEKYEKARLLKDYILGIRAA 1387
            KE+RHDNTVTWLA+WNDPIN KEFKYVFLAASS+LKGQSDKEKYEKAR+LKDYI  IR A
Sbjct: 529  KEVRHDNTVTWLAFWNDPINQKEFKYVFLAASSSLKGQSDKEKYEKARMLKDYIKNIRNA 588

Query: 1386 YTKDFTSKDPAKRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVEPVPPNTLK 1207
            YTKDFTSKDP +RQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENV+ VPPN L+
Sbjct: 589  YTKDFTSKDPTRRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVKAVPPNLLE 648

Query: 1206 FDFLGKDSIRYQNEVEVETAVFKAIQQFRSGKKGGDDLFDRLDTSKLNAHLKELMPGLTA 1027
            F+FLGKDSIRY+N VEVE  VFKAI QF+SGK G DDLFD+LDTSKLNAHLK+LMPGLTA
Sbjct: 649  FNFLGKDSIRYENTVEVELPVFKAITQFQSGKSGTDDLFDKLDTSKLNAHLKDLMPGLTA 708

Query: 1026 KVFRTYNASITLDDMLSRETRGGDVAEKVVVYQHANKEVAIICNHQRTVSKSHSAQMLRL 847
            KVFRTYNASITLDDML+R T+ G+V+EK+V YQHANKEVAIICNHQRTVSKSH AQM RL
Sbjct: 709  KVFRTYNASITLDDMLNRGTKNGEVSEKIVTYQHANKEVAIICNHQRTVSKSHGAQMTRL 768

Query: 846  NEKIEELKGVVEELQTDLARAKKGKPPLKSADGKPKRNLNPDALERKIAQTTAKIEKMER 667
            NEKI EL+ +++EL+ DL RAKKGKPPLK +DGK KRNL P+ALE+KI+QT AKIEK+ER
Sbjct: 769  NEKISELRDILKELKIDLDRAKKGKPPLKGSDGKQKRNLTPEALEKKISQTNAKIEKIER 828

Query: 666  DKETKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFAWAMDVDPGFR 487
            D +TKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFAWAMDVDP FR
Sbjct: 829  DMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFAWAMDVDPDFR 888

Query: 486  F 484
            F
Sbjct: 889  F 889


>ref|XP_006474977.1| PREDICTED: DNA topoisomerase 1-like isoform X1 [Citrus sinensis]
            gi|568842074|ref|XP_006474978.1| PREDICTED: DNA
            topoisomerase 1-like isoform X2 [Citrus sinensis]
            gi|568842076|ref|XP_006474979.1| PREDICTED: DNA
            topoisomerase 1-like isoform X3 [Citrus sinensis]
            gi|568842078|ref|XP_006474980.1| PREDICTED: DNA
            topoisomerase 1-like isoform X4 [Citrus sinensis]
          Length = 902

 Score = 1016 bits (2626), Expect = 0.0
 Identities = 561/921 (60%), Positives = 644/921 (69%), Gaps = 28/921 (3%)
 Frame = -3

Query: 3162 MAVEACDK-QKLXXXXXXXXEPLVFKRXXXXXXXXXXXSEAKKSLSQKHDRQLGRPAPDV 2986
            MAVEA  K  ++         P VFKR            E K+              P  
Sbjct: 1    MAVEASSKPSRVYDFDDDEDGPAVFKRNTAASRQNLANPEVKR--------------PSS 46

Query: 2985 RSQNGQSTIVKKSKT-VPLSKTPPVKYPLTSPKSSNTSGKALA----------------L 2857
             + NGQ++   K KT V  SK  PVK P  S K++ +S KA                  +
Sbjct: 47   STANGQNSNAPKDKTTVSSSKVLPVKSPPPSQKATTSSAKASPSKSPMRSPVKSPVRSPV 106

Query: 2856 KSPEVDSKPSTSVTDK-SNSVKHQ----IKDEKLSTEATGEPNEDSQDSEDDKPLSARLP 2692
            KSP  +SK S+ + D+   S +H     +K E++  +  G  ++D+ DSEDDKPLSARL 
Sbjct: 107  KSPVANSKESSPLDDRLKQSPQHNALAVVKKEEIK-DGNGLKSDDN-DSEDDKPLSARLK 164

Query: 2691 AGLSKVNSNHAKKSPNTSTLSQKRRIPIPEDSDDEIPLSSKFQVKSNAGESINRSSNSGE 2512
                 VN        + + +S+      PEDSDDE+PLSS+F  KSNAG S  +  +S E
Sbjct: 165  GNSKNVNQGIGASKADAA-ISEVNVKTDPEDSDDEVPLSSRFP-KSNAGTSGAKPIDSDE 222

Query: 2511 RKPLLSKYDQNGSAS--TERKPSTNLKKRPGDGVKTTDESYLKKPKLSEAATPHKNKEAS 2338
            +KPL SK  QNGS S  T++K S+   KRP     ++  S  KKPK+S+ +   K K+ +
Sbjct: 223  KKPLASKVQQNGSTSRETQQKSSSVPVKRPLQKASSSGASSAKKPKVSDTSKEVKVKQVT 282

Query: 2337 IKAEMREEDDEDHVPISHRMXXXXXXXXXXXXXK-NITKPIXXXXXXXXXXXXXXXXXXX 2161
            +K E ++ DD+DH+PIS RM                 TK +                   
Sbjct: 283  VKVE-KKADDDDHIPISQRMKNSAPSVKKSVTNTAKATKSVSSSSNKINKKTKKVIKNSQ 341

Query: 2160 XXXXXXXXXXSGEGQK-WTTLVHNGVIFPPPYKPHGVKMLYKGKPVDLTPEQEEVATMYA 1984
                      SG+GQK WTTLVHNGVIFPPPY PHGVKMLYKGK V+LTPEQEEVATM+A
Sbjct: 342  YSKSTKMLPGSGDGQKKWTTLVHNGVIFPPPYLPHGVKMLYKGKEVNLTPEQEEVATMFA 401

Query: 1983 VMLETDYMNKPKFKENFMADWRKILGKNHTIQSLEHCDFTPIYEWHXXXXXXXXXXXXXX 1804
            VML+TDYM KPKF+ENF  DWRK+LGKNH IQ+LE CDF PIY+WH              
Sbjct: 402  VMLDTDYMQKPKFRENFWNDWRKLLGKNHVIQNLEGCDFKPIYDWHQEQKEKKKQMSSEE 461

Query: 1803 XXXXXXXXXXXXXKYMWAIVNGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIRPSDIT 1624
                         KYMWAIV+GVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRI+PSDIT
Sbjct: 462  KKALKEEKLKQEEKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIQPSDIT 521

Query: 1623 INIGKDAPIPECPIPGESWKEIRHDNTVTWLAYWNDPINPKEFKYVFLAASSTLKGQSDK 1444
            INIGKD PIPECPIPGESWKE++HDNTVTWLA+WNDPINPKEFKYVFLAASS+LKGQSDK
Sbjct: 522  INIGKDVPIPECPIPGESWKEVKHDNTVTWLAFWNDPINPKEFKYVFLAASSSLKGQSDK 581

Query: 1443 EKYEKARLLKDYILGIRAAYTKDFTSKDPAKRQIAVATYLIDKLALRAGNEKDDDEADTV 1264
            EKYEKAR LKDYI  IRAAYTKDF S+D  +RQIAVATYLIDKLALRAGNEKDDDEADTV
Sbjct: 582  EKYEKARKLKDYIHSIRAAYTKDFVSRDGTRRQIAVATYLIDKLALRAGNEKDDDEADTV 641

Query: 1263 GCCTLKVENVEPVPPNTLKFDFLGKDSIRYQNEVEVETAVFKAIQQFRSGKKGGDDLFDR 1084
            GCCTLKV NVE +PPN LKFDFLGKDSI+Y N VEVE  V+KAI QF++GKK  DDLFD+
Sbjct: 642  GCCTLKVGNVECIPPNKLKFDFLGKDSIQYVNTVEVELPVYKAIGQFQTGKKQNDDLFDK 701

Query: 1083 LDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSRETRGGDVAEKVVVYQHANKEVAI 904
            LDT+KLNAHLKELMPGLTAKVFRTYNASITLD ML++ T  GDVA K+ VYQ ANKEVAI
Sbjct: 702  LDTAKLNAHLKELMPGLTAKVFRTYNASITLDGMLNKGTGDGDVAVKIDVYQRANKEVAI 761

Query: 903  ICNHQRTVSKSHSAQMLRLNEKIEELKGVVEELQTDLARAKKGKPPL-KSADGKPKRNLN 727
            ICNHQRTVSK+HSAQM RL EKIE+LKGV+++L+ DL RAKKGKPPL K +DGK KRNL 
Sbjct: 762  ICNHQRTVSKTHSAQMSRLTEKIEDLKGVLKDLRVDLDRAKKGKPPLMKDSDGKRKRNLA 821

Query: 726  PDALERKIAQTTAKIEKMERDKETKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKI 547
            P+ALERK+AQT AKIEKMERD +TKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKI
Sbjct: 822  PEALERKMAQTNAKIEKMERDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKI 881

Query: 546  FNKSLLAKFAWAMDVDPGFRF 484
            FNKSLLAKFAWAMDVDP FRF
Sbjct: 882  FNKSLLAKFAWAMDVDPEFRF 902


>ref|XP_006452479.1| hypothetical protein CICLE_v10007398mg [Citrus clementina]
            gi|567920950|ref|XP_006452481.1| hypothetical protein
            CICLE_v10007398mg [Citrus clementina]
            gi|557555705|gb|ESR65719.1| hypothetical protein
            CICLE_v10007398mg [Citrus clementina]
            gi|557555707|gb|ESR65721.1| hypothetical protein
            CICLE_v10007398mg [Citrus clementina]
          Length = 902

 Score = 1015 bits (2625), Expect = 0.0
 Identities = 559/921 (60%), Positives = 642/921 (69%), Gaps = 28/921 (3%)
 Frame = -3

Query: 3162 MAVEACDK-QKLXXXXXXXXEPLVFKRXXXXXXXXXXXSEAKKSLSQKHDRQLGRPAPDV 2986
            MAVEA  K  ++         P VFKR            E K+              P  
Sbjct: 1    MAVEASSKPSRVYDFDDDEDGPAVFKRNTAASRQNLANPEVKR--------------PSS 46

Query: 2985 RSQNGQSTIVKKSKT-VPLSKTPPVKYPLTSPKSSNTSGKALALKSPE------------ 2845
             + NGQ++   K KT V  SK  PVK P  S K++ +S KA  LKSP             
Sbjct: 47   STANGQNSNAPKDKTTVSSSKVLPVKSPPPSQKATTSSAKASPLKSPMRSPVKSPVRSPV 106

Query: 2844 ----VDSKPSTSVTDKSNSVKHQ-----IKDEKLSTEATGEPNEDSQDSEDDKPLSARLP 2692
                 +SK S+ + D+   +        +K E++  +  G  ++D+ DSEDDKPLSARL 
Sbjct: 107  KSPVANSKESSPLDDRLKQLPQHNALAVVKKEEIK-DGNGLKSDDN-DSEDDKPLSARLK 164

Query: 2691 AGLSKVNSNHAKKSPNTSTLSQKRRIPIPEDSDDEIPLSSKFQVKSNAGESINRSSNSGE 2512
                 VN        + + +S+      PEDSDDE+PLSS+F  KSNAG S  +  +S E
Sbjct: 165  GNTKNVNQGIGASKADAA-ISEVNVKTDPEDSDDEVPLSSRFP-KSNAGTSGAKPIDSDE 222

Query: 2511 RKPLLSKYDQNGSAS--TERKPSTNLKKRPGDGVKTTDESYLKKPKLSEAATPHKNKEAS 2338
            +KPL SK  QNGS S  T++K S+   KRP     ++  S  KKPK+S+ +   K K+ +
Sbjct: 223  KKPLASKVQQNGSTSRETQQKSSSVPVKRPLQKASSSGASSAKKPKVSDTSKEVKVKQVT 282

Query: 2337 IKAEMREEDDEDHVPISHRMXXXXXXXXXXXXXK-NITKPIXXXXXXXXXXXXXXXXXXX 2161
            +K E ++ DD+DH+PIS RM                 TK +                   
Sbjct: 283  VKVE-KKADDDDHIPISQRMKNSAPSVKKSVTNTAKATKSVSSSSKKINKKTKKVIKNSQ 341

Query: 2160 XXXXXXXXXXSGEGQK-WTTLVHNGVIFPPPYKPHGVKMLYKGKPVDLTPEQEEVATMYA 1984
                      SG+GQK WTTLVHNGVIFPPPY PHGVKMLYKGK V+LTPEQEEVATM+A
Sbjct: 342  YSKSTKMLPGSGDGQKKWTTLVHNGVIFPPPYLPHGVKMLYKGKEVNLTPEQEEVATMFA 401

Query: 1983 VMLETDYMNKPKFKENFMADWRKILGKNHTIQSLEHCDFTPIYEWHXXXXXXXXXXXXXX 1804
            VML+TDYM KPKF+ENF  DWRK+LGKNH IQ+LE CDF PIY+WH              
Sbjct: 402  VMLDTDYMQKPKFRENFWNDWRKLLGKNHVIQNLEGCDFKPIYDWHQEQKEKKKQMSSEE 461

Query: 1803 XXXXXXXXXXXXXKYMWAIVNGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIRPSDIT 1624
                         KYMWAIV+GVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRI+PSDIT
Sbjct: 462  KKALKEEKLKQEEKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIQPSDIT 521

Query: 1623 INIGKDAPIPECPIPGESWKEIRHDNTVTWLAYWNDPINPKEFKYVFLAASSTLKGQSDK 1444
            INIGKD PIPECPIPGESWKE++HDNTVTWLA+WNDPINPKEFKYVFLAASS+LKGQSD+
Sbjct: 522  INIGKDVPIPECPIPGESWKEVKHDNTVTWLAFWNDPINPKEFKYVFLAASSSLKGQSDR 581

Query: 1443 EKYEKARLLKDYILGIRAAYTKDFTSKDPAKRQIAVATYLIDKLALRAGNEKDDDEADTV 1264
            EKYEKAR LKDYI  IRAAYTKDF S+D  +RQIAVATYLIDKLALRAGNEKDDDEADTV
Sbjct: 582  EKYEKARKLKDYIHSIRAAYTKDFVSRDGTRRQIAVATYLIDKLALRAGNEKDDDEADTV 641

Query: 1263 GCCTLKVENVEPVPPNTLKFDFLGKDSIRYQNEVEVETAVFKAIQQFRSGKKGGDDLFDR 1084
            GCCTLKV NVE +PPN LKFDFLGKDSI+Y N VEVE  V+KAI QF++GKK  DDLFD+
Sbjct: 642  GCCTLKVGNVECIPPNKLKFDFLGKDSIQYVNTVEVELPVYKAIGQFQTGKKQNDDLFDK 701

Query: 1083 LDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSRETRGGDVAEKVVVYQHANKEVAI 904
            LDT+KLNAHLKELMPGLTAKVFRTYNASITLD ML++ T  GDVA K+ VYQ ANKEVAI
Sbjct: 702  LDTAKLNAHLKELMPGLTAKVFRTYNASITLDGMLNKGTGDGDVAVKIDVYQRANKEVAI 761

Query: 903  ICNHQRTVSKSHSAQMLRLNEKIEELKGVVEELQTDLARAKKGKPPL-KSADGKPKRNLN 727
            ICNHQRTVSK+HSAQM RL EKIE+LKGV+++L+ DL RAKKGKPPL K +DGK KRNL 
Sbjct: 762  ICNHQRTVSKTHSAQMSRLTEKIEDLKGVLKDLRVDLDRAKKGKPPLMKDSDGKRKRNLA 821

Query: 726  PDALERKIAQTTAKIEKMERDKETKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKI 547
            P+ALERK+AQT AKIEKMERD +TKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKI
Sbjct: 822  PEALERKMAQTNAKIEKMERDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKI 881

Query: 546  FNKSLLAKFAWAMDVDPGFRF 484
            FNKSLLAKFAWAMDVDP FRF
Sbjct: 882  FNKSLLAKFAWAMDVDPEFRF 902


>ref|XP_002300344.1| DNA topoisomerase family protein [Populus trichocarpa]
            gi|222847602|gb|EEE85149.1| DNA topoisomerase family
            protein [Populus trichocarpa]
          Length = 877

 Score = 1006 bits (2602), Expect = 0.0
 Identities = 534/883 (60%), Positives = 616/883 (69%), Gaps = 10/883 (1%)
 Frame = -3

Query: 3102 PLVFKRXXXXXXXXXXXSEAKKSLSQKHDRQLGRPAPDVRSQNGQSTIVKKSKT-VPLSK 2926
            P+VFKR                S   + + +  +P+   ++ NGQS  ++K K+ +P S 
Sbjct: 24   PIVFKRGGN-----------STSKQNQLNPEAKKPSSSSQNSNGQSLNLQKGKSPIPSSN 72

Query: 2925 TPPVKYPLTSPKSSNTSGKALALKSPEVDSKPSTSVTDKSNSVKHQIKDEKLSTEATGEP 2746
              P+K    SPK+S +S KA  LKSP   ++  TS  D+      Q+    +  E   + 
Sbjct: 73   ASPMKSSTGSPKASASSAKASPLKSPLTYTRALTSSNDQLKQASKQVVSNAVKEET--KS 130

Query: 2745 NEDSQDSEDDKPLSARLPAGLSKVNSN-----HAKKSPNTSTLSQKRRIPIPEDSDDEIP 2581
              D +DSEDDKPLS+R+    + VN       H K  P+                DDE+P
Sbjct: 131  IVDDEDSEDDKPLSSRIKGSTNNVNKGVTAPAHVKDEPS---------------DDDEVP 175

Query: 2580 LSSKFQVKSNAGESINRSSNSGERKPLLSKYDQNGSASTERKPSTNL--KKRPGDGVKTT 2407
            LSS+F +KSNAG S ++S  S E +P  SK   NGS   +++  +++   KRP D    +
Sbjct: 176  LSSRFAMKSNAGTSSSKSIRSSEIRPFPSKSQLNGSTKNDKQQKSSVVPTKRPMDNKVPS 235

Query: 2406 DESYLKKPKLSEAATPHKNKEASIKAEMREEDDEDHVPISHRMXXXXXXXXXXXXXKN-I 2230
            + S  KKPKL +A T  K K+ ++K E + +DD DH+ IS RM             K  +
Sbjct: 236  NHSSAKKPKLLDACTTTKVKQVTVKVEQKADDD-DHLTISQRMKKADSSANKSSFAKKKV 294

Query: 2229 TKPIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSGEGQK-WTTLVHNGVIFPPPYKPHGV 2053
            TK +                             S +GQK WTTLVHNGVIFPPPYKPHGV
Sbjct: 295  TKVVSSSLKKTTQKNKKQMKNSKYSKSTKVQPGSSDGQKKWTTLVHNGVIFPPPYKPHGV 354

Query: 2052 KMLYKGKPVDLTPEQEEVATMYAVMLETDYMNKPKFKENFMADWRKILGKNHTIQSLEHC 1873
            K+LYKGKP+DLTPEQEEVATM+AVM +TDY+ KP+F++NF  DWRK+LGKNH IQ L+ C
Sbjct: 355  KILYKGKPIDLTPEQEEVATMFAVMKDTDYVQKPQFRQNFWNDWRKLLGKNHVIQKLDDC 414

Query: 1872 DFTPIYEWHXXXXXXXXXXXXXXXXXXXXXXXXXXXKYMWAIVNGVKEKVGNFRVEPPGL 1693
            DF PIYEWH                           KYMWAIVNGVKEKVGNFRVEPPGL
Sbjct: 415  DFNPIYEWHQQEKEKKKQMSTEEKKVLKEEKLKQEEKYMWAIVNGVKEKVGNFRVEPPGL 474

Query: 1692 FRGRGEHPKMGKLKKRIRPSDITINIGKDAPIPECPIPGESWKEIRHDNTVTWLAYWNDP 1513
            FRGRGEHPKMGKLK RIRPSDITINIGKDAPIPECPIPGE WKE++HDNTVTWLA+WNDP
Sbjct: 475  FRGRGEHPKMGKLKSRIRPSDITINIGKDAPIPECPIPGERWKEVKHDNTVTWLAFWNDP 534

Query: 1512 INPKEFKYVFLAASSTLKGQSDKEKYEKARLLKDYILGIRAAYTKDFTSKDPAKRQIAVA 1333
            INPKEFKYVFLAASS+LKGQSDKEKYEKAR LKDYI  IRAAYTKDF SKD  KRQIAVA
Sbjct: 535  INPKEFKYVFLAASSSLKGQSDKEKYEKARKLKDYIHNIRAAYTKDFASKDITKRQIAVA 594

Query: 1332 TYLIDKLALRAGNEKDDDEADTVGCCTLKVENVEPVPPNTLKFDFLGKDSIRYQNEVEVE 1153
            TYLIDKLALRAGNEKDDDEADTVGCCTLKV NVE +PPN LKFDFLGKDSIRY+N VEVE
Sbjct: 595  TYLIDKLALRAGNEKDDDEADTVGCCTLKVANVECIPPNKLKFDFLGKDSIRYENTVEVE 654

Query: 1152 TAVFKAIQQFRSGKKGGDDLFDRLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSR 973
              V+KAI  F+  KK  DDLFD LDTSKLNAHLKELMPGLTAKVFRTYNASITLD+ L  
Sbjct: 655  LPVYKAIGHFQVAKKQTDDLFDSLDTSKLNAHLKELMPGLTAKVFRTYNASITLDEKLYE 714

Query: 972  ETRGGDVAEKVVVYQHANKEVAIICNHQRTVSKSHSAQMLRLNEKIEELKGVVEELQTDL 793
            ET  GDVAEK+V+Y  ANK+VAIICNHQRT+SKSH AQM RL EKIEELK  ++EL+TDL
Sbjct: 715  ETEDGDVAEKIVIYNQANKQVAIICNHQRTISKSHDAQMSRLTEKIEELKSTLKELKTDL 774

Query: 792  ARAKKGKPPLKSADGKPKRNLNPDALERKIAQTTAKIEKMERDKETKEDLKTVALGTSKI 613
             RAKKGKPPLK ADGK KR+L P+A+E+KIA T  KIEKME   +TKEDLKTVALGTSKI
Sbjct: 775  DRAKKGKPPLKGADGKQKRSLTPEAIEKKIATTNQKIEKMEMAMKTKEDLKTVALGTSKI 834

Query: 612  NYLDPRITVAWCKRHEVPIEKIFNKSLLAKFAWAMDVDPGFRF 484
            NYLDPRITVAWCKRHEVPI+KIFNKSLLAKF WAMDVDP FRF
Sbjct: 835  NYLDPRITVAWCKRHEVPIDKIFNKSLLAKFTWAMDVDPQFRF 877