BLASTX nr result
ID: Rehmannia22_contig00030702
seq
BLASTX 2.2.25 [Feb-01-2011]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Rehmannia22_contig00030702
(349 letters)
Database: ./nr
37,332,560 sequences; 13,225,080,153 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
sp|J7LP58.1|TPS1_PHYDL RecName: Full=Bifunctional sesquiterpene ... 160 1e-37
sp|Q49SP3.1|TPSPS_POGCB RecName: Full=Patchoulol synthase; Short... 151 7e-35
sp|J7LMP2.1|TPS5_PHYDL RecName: Full=Bicyclogermacrene synthase;... 151 1e-34
sp|Q49SP6.1|TPGD2_POGCB RecName: Full=Germacrene D synthase 2; A... 144 2e-32
emb|CBI20475.3| unnamed protein product [Vitis vinifera] 137 1e-30
ref|XP_002283076.1| PREDICTED: (-)-germacrene D synthase [Vitis ... 137 1e-30
ref|XP_002282488.1| PREDICTED: (-)-germacrene D synthase [Vitis ... 136 3e-30
ref|XP_002283070.1| PREDICTED: (-)-germacrene D synthase [Vitis ... 135 4e-30
emb|CAN81129.1| hypothetical protein VITISV_002911 [Vitis vinifera] 132 4e-29
emb|CAN68620.1| hypothetical protein VITISV_013313 [Vitis vinifera] 131 1e-28
emb|CAN83470.1| hypothetical protein VITISV_030783 [Vitis vinifera] 130 1e-28
emb|CBI20483.3| unnamed protein product [Vitis vinifera] 130 2e-28
emb|CAN75099.1| hypothetical protein VITISV_019788 [Vitis vinifera] 130 2e-28
ref|XP_006370590.1| hypothetical protein POPTR_0001s44080g [Popu... 129 3e-28
ref|XP_006370589.1| hypothetical protein POPTR_0001s44080g [Popu... 129 3e-28
ref|XP_002277351.2| PREDICTED: valencene synthase-like [Vitis vi... 129 3e-28
gb|AEI52901.1| terpene synthase 1 [Populus trichocarpa] 129 3e-28
gb|ADR74200.1| beta-curcumene synthase [Vitis vinifera] 129 3e-28
emb|CBI31313.3| unnamed protein product [Vitis vinifera] 129 3e-28
ref|XP_002319795.1| predicted protein [Populus trichocarpa] gi|5... 129 3e-28
>sp|J7LP58.1|TPS1_PHYDL RecName: Full=Bifunctional sesquiterpene synthase 1; AltName:
Full=Alpha-copaene synthase; AltName:
Full=Delta-cadinene synthase; AltName: Full=Terpene
synthase 1; Short=LdTPS1 gi|403084368|gb|AFR23368.1|
alpha-copaene/delta-cadinene synthase [Phyla dulcis]
Length = 564
Score = 160 bits (406), Expect = 1e-37
Identities = 70/103 (67%), Positives = 90/103 (87%)
Frame = -1
Query: 310 KEAFDWVLSKPDIVRATLVICRLTDDIVGHEFERKREHIPSSVECYTSEHKVSKQEAIHE 131
+E FDWVLS PD V A+ +ICRL DDIVGHEFE+ R+HIPSSVECYT EHK SK++A++E
Sbjct: 437 REHFDWVLSDPDFVMASCIICRLADDIVGHEFEQTRDHIPSSVECYTQEHKTSKEDAVNE 496
Query: 130 LTNQIEAAWKDINEGFLKPTKIPAPLLYLILNFARVIEVIYSK 2
L +++E+AWKD+NEGFL+PTKIPA LLY +LN+ R+IEV+YS+
Sbjct: 497 LYDRLESAWKDLNEGFLRPTKIPAALLYRVLNYCRIIEVMYSR 539
>sp|Q49SP3.1|TPSPS_POGCB RecName: Full=Patchoulol synthase; Short=PatTps177; AltName:
Full=Alpha-guaiene synthase; AltName: Full=Delta-guaiene
synthase gi|46254783|gb|AAS86323.1| patchoulol synthase
[Pogostemon cablin] gi|86264162|gb|ABC87816.1|
patchoulol synthase [Pogostemon cablin]
Length = 552
Score = 151 bits (382), Expect = 7e-35
Identities = 67/104 (64%), Positives = 82/104 (78%)
Frame = -1
Query: 313 TKEAFDWVLSKPDIVRATLVICRLTDDIVGHEFERKREHIPSSVECYTSEHKVSKQEAIH 134
TKEAFDWV S+P + ATL+I RL +DI GHEFE+KREH+ ++VECY EHKV KQE +
Sbjct: 424 TKEAFDWVFSRPPFIEATLIIARLVNDITGHEFEKKREHVRTAVECYMEEHKVGKQEVVS 483
Query: 133 ELTNQIEAAWKDINEGFLKPTKIPAPLLYLILNFARVIEVIYSK 2
E NQ+E+AWKDINEGFL+P + P PLLYLILN R +EVIY +
Sbjct: 484 EFYNQMESAWKDINEGFLRPVEFPIPLLYLILNSVRTLEVIYKE 527
>sp|J7LMP2.1|TPS5_PHYDL RecName: Full=Bicyclogermacrene synthase; AltName: Full=Terpene
synthase 5; Short=LdTPS5 gi|403084370|gb|AFR23369.1|
bicyclogermacrene synthase [Phyla dulcis]
Length = 565
Score = 151 bits (381), Expect = 1e-34
Identities = 66/103 (64%), Positives = 88/103 (85%)
Frame = -1
Query: 310 KEAFDWVLSKPDIVRATLVICRLTDDIVGHEFERKREHIPSSVECYTSEHKVSKQEAIHE 131
+EAFDWVLS+PD V+A+L I RL DDIVGHE E+KR H+ SSVECY E K S+++A++E
Sbjct: 437 REAFDWVLSEPDFVKASLTINRLVDDIVGHEDEQKRNHVVSSVECYVQESKTSREDAVYE 496
Query: 130 LTNQIEAAWKDINEGFLKPTKIPAPLLYLILNFARVIEVIYSK 2
L +++E+ WKD+NEGFLKPTK P+PLLY +LN++RVIEV+Y+K
Sbjct: 497 LNSRVESTWKDLNEGFLKPTKFPSPLLYRVLNYSRVIEVMYTK 539
>sp|Q49SP6.1|TPGD2_POGCB RecName: Full=Germacrene D synthase 2; AltName: Full=PatTpsBF2
gi|52139809|gb|AAS86320.1| germacrene D synthase
[Pogostemon cablin]
Length = 554
Score = 144 bits (362), Expect = 2e-32
Identities = 65/105 (61%), Positives = 85/105 (80%)
Frame = -1
Query: 316 ATKEAFDWVLSKPDIVRATLVICRLTDDIVGHEFERKREHIPSSVECYTSEHKVSKQEAI 137
ATKEAFDWVLS+PD+++A + + RLT+DIVG E E++R+HI ++VE Y EHK+S QEA+
Sbjct: 426 ATKEAFDWVLSEPDVMKAAITLARLTNDIVGIELEKERKHIATAVEVYEDEHKLSMQEAM 485
Query: 136 HELTNQIEAAWKDINEGFLKPTKIPAPLLYLILNFARVIEVIYSK 2
E+ NQIE+ WK INE FL+PTK P P+LY ILN+ RV+EVIY K
Sbjct: 486 VEIKNQIESGWKTINEAFLRPTKFPTPILYRILNYCRVLEVIYDK 530
>emb|CBI20475.3| unnamed protein product [Vitis vinifera]
Length = 609
Score = 137 bits (346), Expect = 1e-30
Identities = 63/103 (61%), Positives = 80/103 (77%)
Frame = -1
Query: 316 ATKEAFDWVLSKPDIVRATLVICRLTDDIVGHEFERKREHIPSSVECYTSEHKVSKQEAI 137
ATKEAFDWV + P +VRA+ VICRL DDIV HEFE+KR H+ S+VECY +H V KQEA
Sbjct: 480 ATKEAFDWVFNDPKMVRASSVICRLMDDIVSHEFEQKRGHVASAVECYMKQHGVCKQEAY 539
Query: 136 HELTNQIEAAWKDINEGFLKPTKIPAPLLYLILNFARVIEVIY 8
EL Q+ AWKD+N+ LKPT++P PLL +LNF+RVI+++Y
Sbjct: 540 DELNKQVVNAWKDMNKECLKPTQVPMPLLTRVLNFSRVIDILY 582
>ref|XP_002283076.1| PREDICTED: (-)-germacrene D synthase [Vitis vinifera]
Length = 559
Score = 137 bits (346), Expect = 1e-30
Identities = 63/103 (61%), Positives = 80/103 (77%)
Frame = -1
Query: 316 ATKEAFDWVLSKPDIVRATLVICRLTDDIVGHEFERKREHIPSSVECYTSEHKVSKQEAI 137
ATKEAFDWV + P +VRA+ VICRL DDIV HEFE+KR H+ S+VECY +H V KQEA
Sbjct: 430 ATKEAFDWVFNDPKMVRASSVICRLMDDIVSHEFEQKRGHVASAVECYMKQHGVCKQEAY 489
Query: 136 HELTNQIEAAWKDINEGFLKPTKIPAPLLYLILNFARVIEVIY 8
EL Q+ AWKD+N+ LKPT++P PLL +LNF+RVI+++Y
Sbjct: 490 DELNKQVVNAWKDMNKECLKPTQVPMPLLTRVLNFSRVIDILY 532
>ref|XP_002282488.1| PREDICTED: (-)-germacrene D synthase [Vitis vinifera]
gi|302142994|emb|CBI20289.3| unnamed protein product
[Vitis vinifera] gi|313755468|gb|ADR74225.1|
selina-411-diene/intermedeol synthase [synthetic
construct]
Length = 561
Score = 136 bits (342), Expect = 3e-30
Identities = 61/102 (59%), Positives = 80/102 (78%)
Frame = -1
Query: 313 TKEAFDWVLSKPDIVRATLVICRLTDDIVGHEFERKREHIPSSVECYTSEHKVSKQEAIH 134
TKEAFDWV S P ++RA+ VICRL DDIV HEFE+KR H+ S+VECY ++ VSK+EA
Sbjct: 433 TKEAFDWVFSDPKMIRASNVICRLMDDIVSHEFEQKRGHVASAVECYMKQYGVSKEEAYD 492
Query: 133 ELTNQIEAAWKDINEGFLKPTKIPAPLLYLILNFARVIEVIY 8
E Q+E+AWKD NE FL+PT +P PLL +LNF+R+++V+Y
Sbjct: 493 EFKKQVESAWKDNNEEFLQPTAVPVPLLTRVLNFSRMMDVLY 534
>ref|XP_002283070.1| PREDICTED: (-)-germacrene D synthase [Vitis vinifera]
gi|147769765|emb|CAN76781.1| hypothetical protein
VITISV_000919 [Vitis vinifera]
gi|302143181|emb|CBI20476.3| unnamed protein product
[Vitis vinifera] gi|313755470|gb|ADR74226.1|
cubebol/delta-cadinene synthase [synthetic construct]
Length = 559
Score = 135 bits (341), Expect = 4e-30
Identities = 63/103 (61%), Positives = 78/103 (75%)
Frame = -1
Query: 316 ATKEAFDWVLSKPDIVRATLVICRLTDDIVGHEFERKREHIPSSVECYTSEHKVSKQEAI 137
ATKEAFDWV S P +VRA+ VICRL DDIV HEFE+KR H+ S+VECY + V KQEA
Sbjct: 430 ATKEAFDWVFSDPKMVRASSVICRLMDDIVSHEFEQKRGHVASAVECYMKQRGVCKQEAY 489
Query: 136 HELTNQIEAAWKDINEGFLKPTKIPAPLLYLILNFARVIEVIY 8
EL Q+ WKD+NE LKPT++P PLL +LNF+RVI+++Y
Sbjct: 490 DELNKQVVNGWKDMNEECLKPTQVPMPLLTRVLNFSRVIDILY 532
>emb|CAN81129.1| hypothetical protein VITISV_002911 [Vitis vinifera]
Length = 561
Score = 132 bits (333), Expect = 4e-29
Identities = 60/102 (58%), Positives = 78/102 (76%)
Frame = -1
Query: 313 TKEAFDWVLSKPDIVRATLVICRLTDDIVGHEFERKREHIPSSVECYTSEHKVSKQEAIH 134
TKEAFDWV S P ++RA+ VICRL DDIV HEFE+KR H+ S+VECY ++ VSK+EA
Sbjct: 433 TKEAFDWVFSDPKMIRASNVICRLMDDIVSHEFEQKRGHVASAVECYMKQYGVSKEEAYD 492
Query: 133 ELTNQIEAAWKDINEGFLKPTKIPAPLLYLILNFARVIEVIY 8
E Q+E+AWKD NE L+PT +P PLL +LNF+R+ +V+Y
Sbjct: 493 EFKKQVESAWKDNNEEXLQPTAVPVPLLTRVLNFSRMXDVLY 534
>emb|CAN68620.1| hypothetical protein VITISV_013313 [Vitis vinifera]
Length = 557
Score = 131 bits (329), Expect = 1e-28
Identities = 58/102 (56%), Positives = 76/102 (74%)
Frame = -1
Query: 313 TKEAFDWVLSKPDIVRATLVICRLTDDIVGHEFERKREHIPSSVECYTSEHKVSKQEAIH 134
TKE+FDW+ SKP IVRA+ ++CRL DD+V H+FE+KR H+ S+VECY +H S+QE +
Sbjct: 429 TKESFDWIFSKPKIVRASAIVCRLMDDMVSHKFEQKRGHVASAVECYMKQHGASEQETHN 488
Query: 133 ELTNQIEAAWKDINEGFLKPTKIPAPLLYLILNFARVIEVIY 8
E Q+ AWKDINE L PT +P P+L +LN ARVI+VIY
Sbjct: 489 EFNKQVRDAWKDINEECLIPTAVPMPILMRVLNLARVIDVIY 530
>emb|CAN83470.1| hypothetical protein VITISV_030783 [Vitis vinifera]
Length = 557
Score = 130 bits (328), Expect = 1e-28
Identities = 58/102 (56%), Positives = 75/102 (73%)
Frame = -1
Query: 313 TKEAFDWVLSKPDIVRATLVICRLTDDIVGHEFERKREHIPSSVECYTSEHKVSKQEAIH 134
TKE FDW+ SKP IVRA+ ++CRL DD+V H+FE+KR H+ S+VECY +H S+QE +
Sbjct: 429 TKETFDWIFSKPKIVRASAIVCRLMDDMVSHKFEQKRGHVASAVECYMKQHGASEQETHN 488
Query: 133 ELTNQIEAAWKDINEGFLKPTKIPAPLLYLILNFARVIEVIY 8
E Q+ AWKDINE L PT +P P+L +LN ARVI+VIY
Sbjct: 489 EFNKQVRDAWKDINEECLIPTAVPMPILMRVLNLARVIDVIY 530
>emb|CBI20483.3| unnamed protein product [Vitis vinifera]
Length = 557
Score = 130 bits (327), Expect = 2e-28
Identities = 58/102 (56%), Positives = 76/102 (74%)
Frame = -1
Query: 313 TKEAFDWVLSKPDIVRATLVICRLTDDIVGHEFERKREHIPSSVECYTSEHKVSKQEAIH 134
TKE+FDW+ SKP IVRA+ ++CRL DD+V H+FE+KR H+ S+VECY +H S+QE +
Sbjct: 429 TKESFDWIFSKPKIVRASAIVCRLMDDMVSHKFEQKRGHVASAVECYMKQHGASEQETHN 488
Query: 133 ELTNQIEAAWKDINEGFLKPTKIPAPLLYLILNFARVIEVIY 8
E Q+ AWKDINE L PT +P P+L +LN ARVI+VIY
Sbjct: 489 EFHKQVRDAWKDINEECLIPTAVPMPILMRVLNLARVIDVIY 530
>emb|CAN75099.1| hypothetical protein VITISV_019788 [Vitis vinifera]
Length = 530
Score = 130 bits (327), Expect = 2e-28
Identities = 58/102 (56%), Positives = 76/102 (74%)
Frame = -1
Query: 313 TKEAFDWVLSKPDIVRATLVICRLTDDIVGHEFERKREHIPSSVECYTSEHKVSKQEAIH 134
TKE+FDW+ SKP IVRA+ ++CRL DD+V H+FE+KR H+ S+VECY +H S+QE +
Sbjct: 402 TKESFDWIFSKPKIVRASAIVCRLMDDMVSHKFEQKRGHVASAVECYMKQHGASEQETHN 461
Query: 133 ELTNQIEAAWKDINEGFLKPTKIPAPLLYLILNFARVIEVIY 8
E Q+ AWKDINE L PT +P P+L +LN ARVI+VIY
Sbjct: 462 EFHKQVRDAWKDINEECLIPTAVPMPILMRVLNLARVIDVIY 503
>ref|XP_006370590.1| hypothetical protein POPTR_0001s44080g [Populus trichocarpa]
gi|550349796|gb|ERP67159.1| hypothetical protein
POPTR_0001s44080g [Populus trichocarpa]
Length = 544
Score = 129 bits (325), Expect = 3e-28
Identities = 55/102 (53%), Positives = 76/102 (74%)
Frame = -1
Query: 313 TKEAFDWVLSKPDIVRATLVICRLTDDIVGHEFERKREHIPSSVECYTSEHKVSKQEAIH 134
TK++FDW+ P I++A+ +ICRL DDIV H+FE+KR H+ SS+ECY +H ++QE +H
Sbjct: 416 TKDSFDWLFRGPKILKASEIICRLMDDIVSHKFEQKRGHVASSIECYMKQHGTTEQETVH 475
Query: 133 ELTNQIEAAWKDINEGFLKPTKIPAPLLYLILNFARVIEVIY 8
E Q+ AWKD+NE FL PT +P PLL +LN ARVI+V+Y
Sbjct: 476 EFRKQVTDAWKDVNEEFLHPTAVPMPLLTRMLNLARVIDVVY 517
>ref|XP_006370589.1| hypothetical protein POPTR_0001s44080g [Populus trichocarpa]
gi|566154740|ref|XP_006370592.1| hypothetical protein
POPTR_0001s44080g [Populus trichocarpa]
gi|550349795|gb|ERP67158.1| hypothetical protein
POPTR_0001s44080g [Populus trichocarpa]
gi|550349798|gb|ERP67161.1| hypothetical protein
POPTR_0001s44080g [Populus trichocarpa]
Length = 500
Score = 129 bits (325), Expect = 3e-28
Identities = 55/102 (53%), Positives = 76/102 (74%)
Frame = -1
Query: 313 TKEAFDWVLSKPDIVRATLVICRLTDDIVGHEFERKREHIPSSVECYTSEHKVSKQEAIH 134
TK++FDW+ P I++A+ +ICRL DDIV H+FE+KR H+ SS+ECY +H ++QE +H
Sbjct: 372 TKDSFDWLFRGPKILKASEIICRLMDDIVSHKFEQKRGHVASSIECYMKQHGTTEQETVH 431
Query: 133 ELTNQIEAAWKDINEGFLKPTKIPAPLLYLILNFARVIEVIY 8
E Q+ AWKD+NE FL PT +P PLL +LN ARVI+V+Y
Sbjct: 432 EFRKQVTDAWKDVNEEFLHPTAVPMPLLTRMLNLARVIDVVY 473
>ref|XP_002277351.2| PREDICTED: valencene synthase-like [Vitis vinifera]
Length = 559
Score = 129 bits (325), Expect = 3e-28
Identities = 62/103 (60%), Positives = 76/103 (73%)
Frame = -1
Query: 316 ATKEAFDWVLSKPDIVRATLVICRLTDDIVGHEFERKREHIPSSVECYTSEHKVSKQEAI 137
ATKEAFDWVL+ P IVRA I RL DD+ H+FE++R HI SSVECY ++ VS+Q A
Sbjct: 429 ATKEAFDWVLNGPKIVRACSTIIRLMDDMASHKFEQERGHIASSVECYMKQYSVSEQLAY 488
Query: 136 HELTNQIEAAWKDINEGFLKPTKIPAPLLYLILNFARVIEVIY 8
HEL Q+E AWKDIN+ FL+PT IP PLL +LNFAR + +Y
Sbjct: 489 HELNKQVEKAWKDINQEFLRPTAIPMPLLTRVLNFARTGDFMY 531
>gb|AEI52901.1| terpene synthase 1 [Populus trichocarpa]
Length = 561
Score = 129 bits (325), Expect = 3e-28
Identities = 55/102 (53%), Positives = 76/102 (74%)
Frame = -1
Query: 313 TKEAFDWVLSKPDIVRATLVICRLTDDIVGHEFERKREHIPSSVECYTSEHKVSKQEAIH 134
TK++FDW+ P I++A+ +ICRL DDIV H+FE+KR H+ SS+ECY +H ++QE +H
Sbjct: 433 TKDSFDWLFRGPKILKASEIICRLMDDIVSHKFEQKRGHVASSIECYMKQHGTTEQETVH 492
Query: 133 ELTNQIEAAWKDINEGFLKPTKIPAPLLYLILNFARVIEVIY 8
E Q+ AWKD+NE FL PT +P PLL +LN ARVI+V+Y
Sbjct: 493 EFRKQVTDAWKDVNEEFLHPTAVPMPLLTRMLNLARVIDVVY 534
>gb|ADR74200.1| beta-curcumene synthase [Vitis vinifera]
Length = 559
Score = 129 bits (325), Expect = 3e-28
Identities = 62/103 (60%), Positives = 76/103 (73%)
Frame = -1
Query: 316 ATKEAFDWVLSKPDIVRATLVICRLTDDIVGHEFERKREHIPSSVECYTSEHKVSKQEAI 137
ATKEAFDWVL+ P IVRA I RL DD+ H+FE++R HI SSVECY ++ VS+Q A
Sbjct: 429 ATKEAFDWVLNGPKIVRACSTIIRLMDDMASHKFEQERGHIASSVECYMKQYSVSEQLAY 488
Query: 136 HELTNQIEAAWKDINEGFLKPTKIPAPLLYLILNFARVIEVIY 8
HEL Q+E AWKDIN+ FL+PT IP PLL +LNFAR + +Y
Sbjct: 489 HELNKQVEKAWKDINQEFLRPTAIPMPLLTRVLNFARTGDFMY 531
>emb|CBI31313.3| unnamed protein product [Vitis vinifera]
Length = 606
Score = 129 bits (325), Expect = 3e-28
Identities = 62/103 (60%), Positives = 76/103 (73%)
Frame = -1
Query: 316 ATKEAFDWVLSKPDIVRATLVICRLTDDIVGHEFERKREHIPSSVECYTSEHKVSKQEAI 137
ATKEAFDWVL+ P IVRA I RL DD+ H+FE++R HI SSVECY ++ VS+Q A
Sbjct: 476 ATKEAFDWVLNGPKIVRACSTIIRLMDDMASHKFEQERGHIASSVECYMKQYSVSEQLAY 535
Query: 136 HELTNQIEAAWKDINEGFLKPTKIPAPLLYLILNFARVIEVIY 8
HEL Q+E AWKDIN+ FL+PT IP PLL +LNFAR + +Y
Sbjct: 536 HELNKQVEKAWKDINQEFLRPTAIPMPLLTRVLNFARTGDFMY 578
>ref|XP_002319795.1| predicted protein [Populus trichocarpa]
gi|566154738|ref|XP_006370591.1| hypothetical protein
POPTR_0001s44080g [Populus trichocarpa]
gi|550349797|gb|ERP67160.1| hypothetical protein
POPTR_0001s44080g [Populus trichocarpa]
Length = 561
Score = 129 bits (325), Expect = 3e-28
Identities = 55/102 (53%), Positives = 76/102 (74%)
Frame = -1
Query: 313 TKEAFDWVLSKPDIVRATLVICRLTDDIVGHEFERKREHIPSSVECYTSEHKVSKQEAIH 134
TK++FDW+ P I++A+ +ICRL DDIV H+FE+KR H+ SS+ECY +H ++QE +H
Sbjct: 433 TKDSFDWLFRGPKILKASEIICRLMDDIVSHKFEQKRGHVASSIECYMKQHGTTEQETVH 492
Query: 133 ELTNQIEAAWKDINEGFLKPTKIPAPLLYLILNFARVIEVIY 8
E Q+ AWKD+NE FL PT +P PLL +LN ARVI+V+Y
Sbjct: 493 EFRKQVTDAWKDVNEEFLHPTAVPMPLLTRMLNLARVIDVVY 534