BLASTX 2.2.25 [Feb-01-2011]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= Perilla23_contig00002708
         (2118 letters)

Database: ./nr 
           77,306,371 sequences; 28,104,191,420 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

ref|XP_011073926.1| PREDICTED: DNA topoisomerase 3-beta isoform ...   844   0.0  
ref|XP_011073927.1| PREDICTED: DNA topoisomerase 3-beta isoform ...   837   0.0  
ref|XP_011073925.1| PREDICTED: DNA topoisomerase 3-beta isoform ...   837   0.0  
ref|XP_010650401.1| PREDICTED: DNA topoisomerase 3-beta isoform ...   774   0.0  
ref|XP_010650402.1| PREDICTED: DNA topoisomerase 3-beta isoform ...   774   0.0  
ref|XP_002321105.1| DNA topoisomerase family protein [Populus tr...   769   0.0  
ref|XP_006358793.1| PREDICTED: DNA topoisomerase 3-beta-1-like i...   778   0.0  
ref|XP_006358794.1| PREDICTED: DNA topoisomerase 3-beta-1-like i...   778   0.0  
ref|XP_009619599.1| PREDICTED: DNA topoisomerase 3-beta isoform ...   780   0.0  
ref|XP_009619600.1| PREDICTED: DNA topoisomerase 3-beta isoform ...   780   0.0  
ref|XP_009619602.1| PREDICTED: DNA topoisomerase 3-beta isoform ...   780   0.0  
ref|XP_009765587.1| PREDICTED: DNA topoisomerase 3-beta isoform ...   777   0.0  
ref|XP_009765588.1| PREDICTED: DNA topoisomerase 3-beta isoform ...   777   0.0  
ref|XP_009765589.1| PREDICTED: DNA topoisomerase 3-beta isoform ...   777   0.0  
ref|XP_007034151.1| DNA topoisomerase, type IA, core [Theobroma ...   757   0.0  
ref|XP_004248022.1| PREDICTED: DNA topoisomerase 3-beta isoform ...   769   0.0  
ref|XP_010326952.1| PREDICTED: DNA topoisomerase 3-beta isoform ...   769   0.0  
ref|XP_011000014.1| PREDICTED: DNA topoisomerase 3-beta isoform ...   762   0.0  
ref|XP_011000015.1| PREDICTED: DNA topoisomerase 3-beta isoform ...   762   0.0  
ref|XP_002516387.1| prokaryotic DNA topoisomerase, putative [Ric...   762   0.0  

>ref|XP_011073926.1| PREDICTED: DNA topoisomerase 3-beta isoform X2 [Sesamum indicum]
          Length = 865

 Score =  844 bits (2180), Expect(2) = 0.0
 Identities = 402/463 (86%), Positives = 424/463 (91%), Gaps = 7/463 (1%)
 Frame = -1

Query: 1638 YICQHFLGTLSPECKYTRITVEFESGGESFHCVGQHVTVKGFTSIMPWLAVAEKNIPQFT 1459
            YICQHFLGTLSP+CKYTRI +EFESGGESF+CVGQHV VKGFTSIMPWLAV E NIPQFT
Sbjct: 403  YICQHFLGTLSPDCKYTRIKIEFESGGESFYCVGQHVLVKGFTSIMPWLAVTEINIPQFT 462

Query: 1458 KGQKIDILRIEVEEGSTQPPDYLTESEAISLMEKNGIGTDASIPVHINNICERNYVQVQA 1279
            +GQKIDI RIEV+EGSTQPPDYL+ESE ISLME+NGIGTDASIPVHINNICERNYVQVQA
Sbjct: 463  EGQKIDISRIEVDEGSTQPPDYLSESELISLMEENGIGTDASIPVHINNICERNYVQVQA 522

Query: 1278 GRRLVPTALGISLIRGYQCIDPDLCLPDIRSFIEHQIALVAKGQADHSLVVQHVIEQFKR 1099
            GRRLVPTALGISLIRGYQ IDPDLCLPDIRSFIEHQIALVAKGQADHSLVV+HVIEQFKR
Sbjct: 523  GRRLVPTALGISLIRGYQLIDPDLCLPDIRSFIEHQIALVAKGQADHSLVVEHVIEQFKR 582

Query: 1098 KFIYFVKQIENMDALFEAEFSPLSDSGRVLSKCGKCLRYMKLISSQPSRLYCGTCEEIYY 919
            KFIYFVKQIENMDALFEAEFSPLSDSGRVLSKCGKCLRYMK I +QPSRLYCGTCEEIYY
Sbjct: 583  KFIYFVKQIENMDALFEAEFSPLSDSGRVLSKCGKCLRYMKHIPTQPSRLYCGTCEEIYY 642

Query: 918  TPPKGTIKLYKELICPLDNFELLIFSLPGPEGKSFPFCPYCYNSPPFEGIGNLYGASKTA 739
            TPPKGTIKLYKEL CPLDNFELLIFS+PGPEGKSFPFCPYCYN+PPFEGI NL+GASK++
Sbjct: 643  TPPKGTIKLYKELTCPLDNFELLIFSMPGPEGKSFPFCPYCYNNPPFEGIDNLFGASKSS 702

Query: 738  GAVQLGKGAGMPCFLCPHPTCQHSMISQGVCACPECDGTLVLDPVSAPKWRLYCNMCNCL 559
            G+V+LGKGAGMPCFLCPHPTCQHSMISQGVCACPECDGTLVLDPVSAP+WRLYCNMCNCL
Sbjct: 703  GSVKLGKGAGMPCFLCPHPTCQHSMISQGVCACPECDGTLVLDPVSAPRWRLYCNMCNCL 762

Query: 558  VSLPEGAHRISTTKDHCPNCDSTILEVDFNKKTTPLKDGGTLHIGCILCDELLHSLVEMK 379
            VSLPEGAHRISTT+DHCP CDSTI+EVDFNKKTTPLKDG TLHIGCILCDELL+SLVEMK
Sbjct: 763  VSLPEGAHRISTTRDHCPECDSTIIEVDFNKKTTPLKDGATLHIGCILCDELLYSLVEMK 822

Query: 378  HGKSFR-------YXXXXXXXXXXXXXXXXRKQQDPKMSFRDF 271
            HGKSF                         +KQ DP+MSFRDF
Sbjct: 823  HGKSFSRKARHRGRGRGRGRRGYSGRGRGGKKQHDPRMSFRDF 865



 Score =  276 bits (706), Expect(2) = 0.0
 Identities = 133/158 (84%), Positives = 145/158 (91%)
 Frame = -3

Query: 2116 YIIHQGYELELQWERHRLFDSDVALMFQNLVKEDGMLKVIGMSEKQESKGRPAGLNTVKL 1937
            YI+++GYEL+L W+RHRLFDSDV  MF+N VKEDG LKVIG+SEKQ SKGRP GLNTV L
Sbjct: 239  YIMYKGYELKLDWQRHRLFDSDVTQMFRNFVKEDGFLKVIGISEKQVSKGRPTGLNTVNL 298

Query: 1936 LKVASSSLGFGPQLAMQLAERLYIQGFISYPRTESTAYPSSFDYKGTLGALARNSVFGDY 1757
            LKVASS+LGFGPQLAMQLAERLY QGFISYPRTESTAYP+SFDYKGTLGALARN V+GDY
Sbjct: 299  LKVASSALGFGPQLAMQLAERLYTQGFISYPRTESTAYPASFDYKGTLGALARNPVWGDY 358

Query: 1756 VQLLLSDGYHKPRSGNDAGDHPPITPMCSATEDMLGHD 1643
            VQ LLSDGYHKPRSG DAGDHPPITPM SATE++LGHD
Sbjct: 359  VQQLLSDGYHKPRSGTDAGDHPPITPMSSATENILGHD 396


>ref|XP_011073927.1| PREDICTED: DNA topoisomerase 3-beta isoform X3 [Sesamum indicum]
          Length = 813

 Score =  837 bits (2162), Expect(2) = 0.0
 Identities = 402/470 (85%), Positives = 424/470 (90%), Gaps = 14/470 (2%)
 Frame = -1

Query: 1638 YICQHFLGTLSPECKYTRITVEFESGGESFHCVGQHVTVKGFTSIMPWLAVAEKNIPQFT 1459
            YICQHFLGTLSP+CKYTRI +EFESGGESF+CVGQHV VKGFTSIMPWLAV E NIPQFT
Sbjct: 344  YICQHFLGTLSPDCKYTRIKIEFESGGESFYCVGQHVLVKGFTSIMPWLAVTEINIPQFT 403

Query: 1458 KGQKIDILRIEVEEGSTQPPDYLTESEAISLMEKNGIGTDASIPVHINNICERNYVQVQA 1279
            +GQKIDI RIEV+EGSTQPPDYL+ESE ISLME+NGIGTDASIPVHINNICERNYVQVQA
Sbjct: 404  EGQKIDISRIEVDEGSTQPPDYLSESELISLMEENGIGTDASIPVHINNICERNYVQVQA 463

Query: 1278 GRRLVPTALGISLIRGYQCIDPDLCLPDIRSFIEHQIALVAKGQADHSLVVQHVIEQFKR 1099
            GRRLVPTALGISLIRGYQ IDPDLCLPDIRSFIEHQIALVAKGQADHSLVV+HVIEQFKR
Sbjct: 464  GRRLVPTALGISLIRGYQLIDPDLCLPDIRSFIEHQIALVAKGQADHSLVVEHVIEQFKR 523

Query: 1098 KFIYFVKQIENMDALFEAEFSPLSDSGRVLSKCGKCLRYMKLISSQPSRLYCGTCEEIYY 919
            KFIYFVKQIENMDALFEAEFSPLSDSGRVLSKCGKCLRYMK I +QPSRLYCGTCEEIYY
Sbjct: 524  KFIYFVKQIENMDALFEAEFSPLSDSGRVLSKCGKCLRYMKHIPTQPSRLYCGTCEEIYY 583

Query: 918  TPPKGTIK-------LYKELICPLDNFELLIFSLPGPEGKSFPFCPYCYNSPPFEGIGNL 760
            TPPKGTIK       LYKEL CPLDNFELLIFS+PGPEGKSFPFCPYCYN+PPFEGI NL
Sbjct: 584  TPPKGTIKVSHISPELYKELTCPLDNFELLIFSMPGPEGKSFPFCPYCYNNPPFEGIDNL 643

Query: 759  YGASKTAGAVQLGKGAGMPCFLCPHPTCQHSMISQGVCACPECDGTLVLDPVSAPKWRLY 580
            +GASK++G+V+LGKGAGMPCFLCPHPTCQHSMISQGVCACPECDGTLVLDPVSAP+WRLY
Sbjct: 644  FGASKSSGSVKLGKGAGMPCFLCPHPTCQHSMISQGVCACPECDGTLVLDPVSAPRWRLY 703

Query: 579  CNMCNCLVSLPEGAHRISTTKDHCPNCDSTILEVDFNKKTTPLKDGGTLHIGCILCDELL 400
            CNMCNCLVSLPEGAHRISTT+DHCP CDSTI+EVDFNKKTTPLKDG TLHIGCILCDELL
Sbjct: 704  CNMCNCLVSLPEGAHRISTTRDHCPECDSTIIEVDFNKKTTPLKDGATLHIGCILCDELL 763

Query: 399  HSLVEMKHGKSFR-------YXXXXXXXXXXXXXXXXRKQQDPKMSFRDF 271
            +SLVEMKHGKSF                         +KQ DP+MSFRDF
Sbjct: 764  YSLVEMKHGKSFSRKARHRGRGRGRGRRGYSGRGRGGKKQHDPRMSFRDF 813



 Score =  276 bits (706), Expect(2) = 0.0
 Identities = 133/158 (84%), Positives = 145/158 (91%)
 Frame = -3

Query: 2116 YIIHQGYELELQWERHRLFDSDVALMFQNLVKEDGMLKVIGMSEKQESKGRPAGLNTVKL 1937
            YI+++GYEL+L W+RHRLFDSDV  MF+N VKEDG LKVIG+SEKQ SKGRP GLNTV L
Sbjct: 180  YIMYKGYELKLDWQRHRLFDSDVTQMFRNFVKEDGFLKVIGISEKQVSKGRPTGLNTVNL 239

Query: 1936 LKVASSSLGFGPQLAMQLAERLYIQGFISYPRTESTAYPSSFDYKGTLGALARNSVFGDY 1757
            LKVASS+LGFGPQLAMQLAERLY QGFISYPRTESTAYP+SFDYKGTLGALARN V+GDY
Sbjct: 240  LKVASSALGFGPQLAMQLAERLYTQGFISYPRTESTAYPASFDYKGTLGALARNPVWGDY 299

Query: 1756 VQLLLSDGYHKPRSGNDAGDHPPITPMCSATEDMLGHD 1643
            VQ LLSDGYHKPRSG DAGDHPPITPM SATE++LGHD
Sbjct: 300  VQQLLSDGYHKPRSGTDAGDHPPITPMSSATENILGHD 337


>ref|XP_011073925.1| PREDICTED: DNA topoisomerase 3-beta isoform X1 [Sesamum indicum]
          Length = 872

 Score =  837 bits (2162), Expect(2) = 0.0
 Identities = 402/470 (85%), Positives = 424/470 (90%), Gaps = 14/470 (2%)
 Frame = -1

Query: 1638 YICQHFLGTLSPECKYTRITVEFESGGESFHCVGQHVTVKGFTSIMPWLAVAEKNIPQFT 1459
            YICQHFLGTLSP+CKYTRI +EFESGGESF+CVGQHV VKGFTSIMPWLAV E NIPQFT
Sbjct: 403  YICQHFLGTLSPDCKYTRIKIEFESGGESFYCVGQHVLVKGFTSIMPWLAVTEINIPQFT 462

Query: 1458 KGQKIDILRIEVEEGSTQPPDYLTESEAISLMEKNGIGTDASIPVHINNICERNYVQVQA 1279
            +GQKIDI RIEV+EGSTQPPDYL+ESE ISLME+NGIGTDASIPVHINNICERNYVQVQA
Sbjct: 463  EGQKIDISRIEVDEGSTQPPDYLSESELISLMEENGIGTDASIPVHINNICERNYVQVQA 522

Query: 1278 GRRLVPTALGISLIRGYQCIDPDLCLPDIRSFIEHQIALVAKGQADHSLVVQHVIEQFKR 1099
            GRRLVPTALGISLIRGYQ IDPDLCLPDIRSFIEHQIALVAKGQADHSLVV+HVIEQFKR
Sbjct: 523  GRRLVPTALGISLIRGYQLIDPDLCLPDIRSFIEHQIALVAKGQADHSLVVEHVIEQFKR 582

Query: 1098 KFIYFVKQIENMDALFEAEFSPLSDSGRVLSKCGKCLRYMKLISSQPSRLYCGTCEEIYY 919
            KFIYFVKQIENMDALFEAEFSPLSDSGRVLSKCGKCLRYMK I +QPSRLYCGTCEEIYY
Sbjct: 583  KFIYFVKQIENMDALFEAEFSPLSDSGRVLSKCGKCLRYMKHIPTQPSRLYCGTCEEIYY 642

Query: 918  TPPKGTIK-------LYKELICPLDNFELLIFSLPGPEGKSFPFCPYCYNSPPFEGIGNL 760
            TPPKGTIK       LYKEL CPLDNFELLIFS+PGPEGKSFPFCPYCYN+PPFEGI NL
Sbjct: 643  TPPKGTIKVSHISPELYKELTCPLDNFELLIFSMPGPEGKSFPFCPYCYNNPPFEGIDNL 702

Query: 759  YGASKTAGAVQLGKGAGMPCFLCPHPTCQHSMISQGVCACPECDGTLVLDPVSAPKWRLY 580
            +GASK++G+V+LGKGAGMPCFLCPHPTCQHSMISQGVCACPECDGTLVLDPVSAP+WRLY
Sbjct: 703  FGASKSSGSVKLGKGAGMPCFLCPHPTCQHSMISQGVCACPECDGTLVLDPVSAPRWRLY 762

Query: 579  CNMCNCLVSLPEGAHRISTTKDHCPNCDSTILEVDFNKKTTPLKDGGTLHIGCILCDELL 400
            CNMCNCLVSLPEGAHRISTT+DHCP CDSTI+EVDFNKKTTPLKDG TLHIGCILCDELL
Sbjct: 763  CNMCNCLVSLPEGAHRISTTRDHCPECDSTIIEVDFNKKTTPLKDGATLHIGCILCDELL 822

Query: 399  HSLVEMKHGKSFR-------YXXXXXXXXXXXXXXXXRKQQDPKMSFRDF 271
            +SLVEMKHGKSF                         +KQ DP+MSFRDF
Sbjct: 823  YSLVEMKHGKSFSRKARHRGRGRGRGRRGYSGRGRGGKKQHDPRMSFRDF 872



 Score =  276 bits (706), Expect(2) = 0.0
 Identities = 133/158 (84%), Positives = 145/158 (91%)
 Frame = -3

Query: 2116 YIIHQGYELELQWERHRLFDSDVALMFQNLVKEDGMLKVIGMSEKQESKGRPAGLNTVKL 1937
            YI+++GYEL+L W+RHRLFDSDV  MF+N VKEDG LKVIG+SEKQ SKGRP GLNTV L
Sbjct: 239  YIMYKGYELKLDWQRHRLFDSDVTQMFRNFVKEDGFLKVIGISEKQVSKGRPTGLNTVNL 298

Query: 1936 LKVASSSLGFGPQLAMQLAERLYIQGFISYPRTESTAYPSSFDYKGTLGALARNSVFGDY 1757
            LKVASS+LGFGPQLAMQLAERLY QGFISYPRTESTAYP+SFDYKGTLGALARN V+GDY
Sbjct: 299  LKVASSALGFGPQLAMQLAERLYTQGFISYPRTESTAYPASFDYKGTLGALARNPVWGDY 358

Query: 1756 VQLLLSDGYHKPRSGNDAGDHPPITPMCSATEDMLGHD 1643
            VQ LLSDGYHKPRSG DAGDHPPITPM SATE++LGHD
Sbjct: 359  VQQLLSDGYHKPRSGTDAGDHPPITPMSSATENILGHD 396


>ref|XP_010650401.1| PREDICTED: DNA topoisomerase 3-beta isoform X1 [Vitis vinifera]
          Length = 871

 Score =  774 bits (1998), Expect(2) = 0.0
 Identities = 362/462 (78%), Positives = 397/462 (85%), Gaps = 6/462 (1%)
 Frame = -1

Query: 1638 YICQHFLGTLSPECKYTRITVEFESGGESFHCVGQHVTVKGFTSIMPWLAVAEKNIPQFT 1459
            Y+CQHF+GT+SP+CKY R  VEF  GGE F C+GQHV VKGFTSIMPWLAV EKN+PQF 
Sbjct: 410  YVCQHFIGTVSPDCKYVRNKVEFSIGGEIFRCIGQHVIVKGFTSIMPWLAVNEKNLPQFK 469

Query: 1458 KGQKIDILRIEVEEGSTQPPDYLTESEAISLMEKNGIGTDASIPVHINNICERNYVQVQA 1279
            KG+KI++ ++E+ EG T PPDYL+ESE ISLMEKNGIGTDASIPVHINNICERN+VQVQA
Sbjct: 470  KGEKIEVSKVELYEGETSPPDYLSESELISLMEKNGIGTDASIPVHINNICERNFVQVQA 529

Query: 1278 GRRLVPTALGISLIRGYQCIDPDLCLPDIRSFIEHQIALVAKGQADHSLVVQHVIEQFKR 1099
            GR+LVPTALGISLIRGYQCIDPDLCLPDIRSFIE QI LVAKGQ DHS VV+HV++QFK+
Sbjct: 530  GRKLVPTALGISLIRGYQCIDPDLCLPDIRSFIEQQITLVAKGQVDHSRVVEHVLQQFKQ 589

Query: 1098 KFIYFVKQIENMDALFEAEFSPLSDSGRVLSKCGKCLRYMKLISSQPSRLYCGTCEEIYY 919
            KFIYFVKQIENMDALFEA+FSPL+DSGR LSKCGKCLRYMK IS+QPSR+YCGTCEE+YY
Sbjct: 590  KFIYFVKQIENMDALFEAQFSPLADSGRALSKCGKCLRYMKYISTQPSRMYCGTCEEVYY 649

Query: 918  TPPKGTIKLYKELICPLDNFELLIFSLPGPEGKSFPFCPYCYNSPPFEGIGNLYGASKTA 739
             P KGTIKLYKEL CPLDNFELLIFSL GPEGKSFP CPYCYNSPPFEGI  L+GA+KT+
Sbjct: 650  LPQKGTIKLYKELTCPLDNFELLIFSLAGPEGKSFPLCPYCYNSPPFEGIDTLFGATKTS 709

Query: 738  GAVQLGKGAGMPCFLCPHPTCQHSMISQGVCACPECDGTLVLDPVSAPKWRLYCNMCNCL 559
               +LGKGAGMPCFLCPHPTC HS+I+QGVCACPEC GTLVLDPVSAPKWRLYCNMCNCL
Sbjct: 710  STGKLGKGAGMPCFLCPHPTCPHSLIAQGVCACPECSGTLVLDPVSAPKWRLYCNMCNCL 769

Query: 558  VSLPEGAHRISTTKDHCPNCDSTILEVDFNKKTTPLKDGGTLHIGCILCDELLHSLVEMK 379
            V LP+GAH+ISTT+D CP C+STILEVDFNKKTTPL DG TL+ GCILCDELLHSLVEMK
Sbjct: 770  VYLPQGAHKISTTRDRCPECESTILEVDFNKKTTPLLDGSTLYTGCILCDELLHSLVEMK 829

Query: 378  HGKSF------RYXXXXXXXXXXXXXXXXRKQQDPKMSFRDF 271
            HGKSF      R                  K  DPKMSFRDF
Sbjct: 830  HGKSFFKRMGSRGRGRGSGRGGFRGRGRGGKWDDPKMSFRDF 871



 Score =  251 bits (640), Expect(2) = 0.0
 Identities = 119/158 (75%), Positives = 137/158 (86%)
 Frame = -3

Query: 2116 YIIHQGYELELQWERHRLFDSDVALMFQNLVKEDGMLKVIGMSEKQESKGRPAGLNTVKL 1937
            YI H GYEL+L+WER++LFD DVA+MFQNLV EDG+++V  +SEKQESK RP+GLNTV L
Sbjct: 246  YITHNGYELQLEWERNKLFDLDVAVMFQNLVMEDGIVEVTDISEKQESKSRPSGLNTVNL 305

Query: 1936 LKVASSSLGFGPQLAMQLAERLYIQGFISYPRTESTAYPSSFDYKGTLGALARNSVFGDY 1757
            LKVASS+LGFGPQ+AMQLAERLY QGFISYPRTESTAYPSSFD+K TLG    N  +GDY
Sbjct: 306  LKVASSALGFGPQMAMQLAERLYTQGFISYPRTESTAYPSSFDFKSTLGMQTNNPTWGDY 365

Query: 1756 VQLLLSDGYHKPRSGNDAGDHPPITPMCSATEDMLGHD 1643
            VQ LL DG+H+PRSG DAGDHPPITPM +A EDMLG+D
Sbjct: 366  VQKLLDDGFHRPRSGTDAGDHPPITPMRAANEDMLGND 403


>ref|XP_010650402.1| PREDICTED: DNA topoisomerase 3-beta isoform X2 [Vitis vinifera]
          Length = 806

 Score =  774 bits (1998), Expect(2) = 0.0
 Identities = 362/462 (78%), Positives = 397/462 (85%), Gaps = 6/462 (1%)
 Frame = -1

Query: 1638 YICQHFLGTLSPECKYTRITVEFESGGESFHCVGQHVTVKGFTSIMPWLAVAEKNIPQFT 1459
            Y+CQHF+GT+SP+CKY R  VEF  GGE F C+GQHV VKGFTSIMPWLAV EKN+PQF 
Sbjct: 345  YVCQHFIGTVSPDCKYVRNKVEFSIGGEIFRCIGQHVIVKGFTSIMPWLAVNEKNLPQFK 404

Query: 1458 KGQKIDILRIEVEEGSTQPPDYLTESEAISLMEKNGIGTDASIPVHINNICERNYVQVQA 1279
            KG+KI++ ++E+ EG T PPDYL+ESE ISLMEKNGIGTDASIPVHINNICERN+VQVQA
Sbjct: 405  KGEKIEVSKVELYEGETSPPDYLSESELISLMEKNGIGTDASIPVHINNICERNFVQVQA 464

Query: 1278 GRRLVPTALGISLIRGYQCIDPDLCLPDIRSFIEHQIALVAKGQADHSLVVQHVIEQFKR 1099
            GR+LVPTALGISLIRGYQCIDPDLCLPDIRSFIE QI LVAKGQ DHS VV+HV++QFK+
Sbjct: 465  GRKLVPTALGISLIRGYQCIDPDLCLPDIRSFIEQQITLVAKGQVDHSRVVEHVLQQFKQ 524

Query: 1098 KFIYFVKQIENMDALFEAEFSPLSDSGRVLSKCGKCLRYMKLISSQPSRLYCGTCEEIYY 919
            KFIYFVKQIENMDALFEA+FSPL+DSGR LSKCGKCLRYMK IS+QPSR+YCGTCEE+YY
Sbjct: 525  KFIYFVKQIENMDALFEAQFSPLADSGRALSKCGKCLRYMKYISTQPSRMYCGTCEEVYY 584

Query: 918  TPPKGTIKLYKELICPLDNFELLIFSLPGPEGKSFPFCPYCYNSPPFEGIGNLYGASKTA 739
             P KGTIKLYKEL CPLDNFELLIFSL GPEGKSFP CPYCYNSPPFEGI  L+GA+KT+
Sbjct: 585  LPQKGTIKLYKELTCPLDNFELLIFSLAGPEGKSFPLCPYCYNSPPFEGIDTLFGATKTS 644

Query: 738  GAVQLGKGAGMPCFLCPHPTCQHSMISQGVCACPECDGTLVLDPVSAPKWRLYCNMCNCL 559
               +LGKGAGMPCFLCPHPTC HS+I+QGVCACPEC GTLVLDPVSAPKWRLYCNMCNCL
Sbjct: 645  STGKLGKGAGMPCFLCPHPTCPHSLIAQGVCACPECSGTLVLDPVSAPKWRLYCNMCNCL 704

Query: 558  VSLPEGAHRISTTKDHCPNCDSTILEVDFNKKTTPLKDGGTLHIGCILCDELLHSLVEMK 379
            V LP+GAH+ISTT+D CP C+STILEVDFNKKTTPL DG TL+ GCILCDELLHSLVEMK
Sbjct: 705  VYLPQGAHKISTTRDRCPECESTILEVDFNKKTTPLLDGSTLYTGCILCDELLHSLVEMK 764

Query: 378  HGKSF------RYXXXXXXXXXXXXXXXXRKQQDPKMSFRDF 271
            HGKSF      R                  K  DPKMSFRDF
Sbjct: 765  HGKSFFKRMGSRGRGRGSGRGGFRGRGRGGKWDDPKMSFRDF 806



 Score =  251 bits (640), Expect(2) = 0.0
 Identities = 119/158 (75%), Positives = 137/158 (86%)
 Frame = -3

Query: 2116 YIIHQGYELELQWERHRLFDSDVALMFQNLVKEDGMLKVIGMSEKQESKGRPAGLNTVKL 1937
            YI H GYEL+L+WER++LFD DVA+MFQNLV EDG+++V  +SEKQESK RP+GLNTV L
Sbjct: 181  YITHNGYELQLEWERNKLFDLDVAVMFQNLVMEDGIVEVTDISEKQESKSRPSGLNTVNL 240

Query: 1936 LKVASSSLGFGPQLAMQLAERLYIQGFISYPRTESTAYPSSFDYKGTLGALARNSVFGDY 1757
            LKVASS+LGFGPQ+AMQLAERLY QGFISYPRTESTAYPSSFD+K TLG    N  +GDY
Sbjct: 241  LKVASSALGFGPQMAMQLAERLYTQGFISYPRTESTAYPSSFDFKSTLGMQTNNPTWGDY 300

Query: 1756 VQLLLSDGYHKPRSGNDAGDHPPITPMCSATEDMLGHD 1643
            VQ LL DG+H+PRSG DAGDHPPITPM +A EDMLG+D
Sbjct: 301  VQKLLDDGFHRPRSGTDAGDHPPITPMRAANEDMLGND 338


>ref|XP_002321105.1| DNA topoisomerase family protein [Populus trichocarpa]
            gi|222861878|gb|EEE99420.1| DNA topoisomerase family
            protein [Populus trichocarpa]
          Length = 837

 Score =  769 bits (1985), Expect(2) = 0.0
 Identities = 358/461 (77%), Positives = 397/461 (86%), Gaps = 5/461 (1%)
 Frame = -1

Query: 1638 YICQHFLGTLSPECKYTRITVEFESGGESFHCVGQHVTVKGFTSIMPWLAVAEKNIPQFT 1459
            Y+CQHFLGT+SP+CKYTR  VEF  GGE FHC+G HVTVKGFTSIMPWLAV+EKN+PQF 
Sbjct: 378  YVCQHFLGTVSPDCKYTRTKVEFSIGGEFFHCIGLHVTVKGFTSIMPWLAVSEKNLPQFA 437

Query: 1458 KGQKIDILRIEVEEGSTQPPDYLTESEAISLMEKNGIGTDASIPVHINNICERNYVQVQA 1279
            KG KI++ ++E+ EG T PPDYL+ESE ISLMEKNGIGTDASI VHINNICERNYVQVQA
Sbjct: 438  KGDKIEVSKVELFEGQTVPPDYLSESELISLMEKNGIGTDASISVHINNICERNYVQVQA 497

Query: 1278 GRRLVPTALGISLIRGYQCIDPDLCLPDIRSFIEHQIALVAKGQADHSLVVQHVIEQFKR 1099
            GR+LVPTALGI+LIRGYQCIDPDLCLPDIR FIE QI LVAKG+ADHS VVQHV+EQFKR
Sbjct: 498  GRKLVPTALGITLIRGYQCIDPDLCLPDIRGFIEQQITLVAKGEADHSCVVQHVLEQFKR 557

Query: 1098 KFIYFVKQIENMDALFEAEFSPLSDSGRVLSKCGKCLRYMKLISSQPSRLYCGTCEEIYY 919
            K+ YFVKQI+NMDALFEA+FSPL+DSGR  SKCGKCLRYMK ISSQPSRLYCGTCEE+YY
Sbjct: 558  KYSYFVKQIDNMDALFEAQFSPLADSGRAFSKCGKCLRYMKYISSQPSRLYCGTCEEVYY 617

Query: 918  TPPKGTIKLYKELICPLDNFELLIFSLPGPEGKSFPFCPYCYNSPPFEGIGNLYGASKTA 739
             P KGTIKLYKEL CPLDNFELLIF++ GPEGKSFP CP CYNSPPFEGI  L+GASKT 
Sbjct: 618  LPQKGTIKLYKELTCPLDNFELLIFAMAGPEGKSFPLCPLCYNSPPFEGIDALFGASKTG 677

Query: 738  GAVQLGKGAGMPCFLCPHPTCQHSMISQGVCACPECDGTLVLDPVSAPKWRLYCNMCNCL 559
             +  LGKGAGMPCFLCPHPTC+HS+I+QGVCACPEC+GTLVLDP+SAPKWRLYCNMCNCL
Sbjct: 678  SSGMLGKGAGMPCFLCPHPTCRHSLIAQGVCACPECNGTLVLDPISAPKWRLYCNMCNCL 737

Query: 558  VSLPEGAHRISTTKDHCPNCDSTILEVDFNKKTTPLKDGGTLHIGCILCDELLHSLVEMK 379
            V LP+GAHRISTT++ CP CDSTI+EVDFNK TTPL+DG TLH+GCILCD LLHSLVE+K
Sbjct: 738  VLLPQGAHRISTTREQCPECDSTIIEVDFNKNTTPLEDGATLHVGCILCDNLLHSLVEVK 797

Query: 378  HGKSF-----RYXXXXXXXXXXXXXXXXRKQQDPKMSFRDF 271
            HGKSF     ++                 K  DPKMSFRDF
Sbjct: 798  HGKSFFKRAGKWARARGRGAYRGRGRGLGK-MDPKMSFRDF 837



 Score =  254 bits (649), Expect(2) = 0.0
 Identities = 123/158 (77%), Positives = 139/158 (87%)
 Frame = -3

Query: 2116 YIIHQGYELELQWERHRLFDSDVALMFQNLVKEDGMLKVIGMSEKQESKGRPAGLNTVKL 1937
            +++  GYEL+L+WERH+LFD DVALMFQ LV +D +L+V  MSEKQESKGRP GLNTV L
Sbjct: 214  HVMVDGYELQLEWERHKLFDLDVALMFQKLVLQDRILEVTDMSEKQESKGRPPGLNTVNL 273

Query: 1936 LKVASSSLGFGPQLAMQLAERLYIQGFISYPRTESTAYPSSFDYKGTLGALARNSVFGDY 1757
            LK+ASS+LGFGPQ+ MQLAERLYIQGFISYPRTESTAYPSSFD+KGTLGALA N ++GDY
Sbjct: 274  LKIASSALGFGPQVTMQLAERLYIQGFISYPRTESTAYPSSFDFKGTLGALANNPMWGDY 333

Query: 1756 VQLLLSDGYHKPRSGNDAGDHPPITPMCSATEDMLGHD 1643
            VQ LLS GYHKP+SG DAGDHPPITPM SA EDMLG D
Sbjct: 334  VQGLLSGGYHKPQSGKDAGDHPPITPMRSANEDMLGRD 371


>ref|XP_006358793.1| PREDICTED: DNA topoisomerase 3-beta-1-like isoform X1 [Solanum
            tuberosum]
          Length = 860

 Score =  778 bits (2009), Expect(2) = 0.0
 Identities = 364/458 (79%), Positives = 397/458 (86%), Gaps = 2/458 (0%)
 Frame = -1

Query: 1638 YICQHFLGTLSPECKYTRITVEFESGGESFHCVGQHVTVKGFTSIMPWLAVAEKNIPQFT 1459
            YICQHFLGTLSP+CKY RI VEFESGGE F CVGQ  TVKGFTSIMPWLA++EKN+P+F 
Sbjct: 403  YICQHFLGTLSPDCKYRRIKVEFESGGEQFQCVGQLATVKGFTSIMPWLAISEKNLPEFA 462

Query: 1458 KGQKIDILRIEVEEGSTQPPDYLTESEAISLMEKNGIGTDASIPVHINNICERNYVQVQA 1279
             G+KI+I + E++EG+T PPDYLTESE ISLMEK+GIGTDASI VHINNICERNYVQVQA
Sbjct: 463  VGEKIEISKAELDEGNTSPPDYLTESELISLMEKHGIGTDASISVHINNICERNYVQVQA 522

Query: 1278 GRRLVPTALGISLIRGYQCIDPDLCLPDIRSFIEHQIALVAKGQADHSLVVQHVIEQFKR 1099
            GRRL PT LGISLIRGYQCID DLCLPDIRSFIEHQI LVAKGQADHS+VVQHV+EQF+R
Sbjct: 523  GRRLAPTPLGISLIRGYQCIDSDLCLPDIRSFIEHQITLVAKGQADHSMVVQHVLEQFRR 582

Query: 1098 KFIYFVKQIENMDALFEAEFSPLSDSGRVLSKCGKCLRYMKLISSQPSRLYCGTCEEIYY 919
            KF YFVKQI+NMDALFEA+FSPLSDSGR+LSKCGKCLRYMK IS+QP+RLYCGTCEE+YY
Sbjct: 583  KFSYFVKQIDNMDALFEAQFSPLSDSGRLLSKCGKCLRYMKYISTQPARLYCGTCEEVYY 642

Query: 918  TPPKGTIKLYKELICPLDNFELLIFSLPGPEGKSFPFCPYCYNSPPFEGIGNLYGASKTA 739
             P KGT+KLYKEL CPLDNFELL+ S+PGPEGKSFP CPYC+N PPFEGI   +GA KT 
Sbjct: 643  VPQKGTVKLYKELTCPLDNFELLLCSMPGPEGKSFPLCPYCFNCPPFEGIDTFFGAPKTG 702

Query: 738  GAVQLGKGAGMPCFLCPHPTCQHSMISQGVCACPECDGTLVLDPVSAPKWRLYCNMCNCL 559
             + +LGKG GMPCFLCPH TC HS+I+QGVCACPEC GTLVLDPVSAPKWRLYCNMCNCL
Sbjct: 703  DSTKLGKGVGMPCFLCPHTTCPHSVIAQGVCACPECSGTLVLDPVSAPKWRLYCNMCNCL 762

Query: 558  VSLPEGAHRISTTKDHCPNCDSTILEVDFNKKTTPLKDGGTLHIGCILCDELLHSLVEMK 379
            VSLPEGAHRISTT+D CP CDSTI+EVDFNKKTTPLKDG TLH GCILCDELLHSLVEMK
Sbjct: 763  VSLPEGAHRISTTQDKCPECDSTIIEVDFNKKTTPLKDGATLHKGCILCDELLHSLVEMK 822

Query: 378  HGKSF--RYXXXXXXXXXXXXXXXXRKQQDPKMSFRDF 271
            HG+SF                     KQQDPKMSFRDF
Sbjct: 823  HGRSFSRHGRRGRGRGRGRGRGRGSTKQQDPKMSFRDF 860



 Score =  243 bits (621), Expect(2) = 0.0
 Identities = 116/158 (73%), Positives = 138/158 (87%)
 Frame = -3

Query: 2116 YIIHQGYELELQWERHRLFDSDVALMFQNLVKEDGMLKVIGMSEKQESKGRPAGLNTVKL 1937
            YI+++GYEL+L+WER RLFD+DV+ MF+N + EDG++KV+ +SEK ESK RP+GLNTV L
Sbjct: 239  YIMYKGYELKLEWERSRLFDADVSAMFRNRIIEDGIMKVVRVSEKLESKARPSGLNTVNL 298

Query: 1936 LKVASSSLGFGPQLAMQLAERLYIQGFISYPRTESTAYPSSFDYKGTLGALARNSVFGDY 1757
            LKVASS+LGFGPQL MQLAERLY QGFISYPRTESTAYPSSFD+KGTLGAL  N VFG Y
Sbjct: 299  LKVASSALGFGPQLTMQLAERLYTQGFISYPRTESTAYPSSFDFKGTLGALVHNPVFGAY 358

Query: 1756 VQLLLSDGYHKPRSGNDAGDHPPITPMCSATEDMLGHD 1643
             Q LL++ Y+KPR+G DAGDHPPITPM SA+ED LG+D
Sbjct: 359  AQKLLTESYNKPRAGTDAGDHPPITPMRSASEDSLGND 396


>ref|XP_006358794.1| PREDICTED: DNA topoisomerase 3-beta-1-like isoform X2 [Solanum
            tuberosum]
          Length = 801

 Score =  778 bits (2009), Expect(2) = 0.0
 Identities = 364/458 (79%), Positives = 397/458 (86%), Gaps = 2/458 (0%)
 Frame = -1

Query: 1638 YICQHFLGTLSPECKYTRITVEFESGGESFHCVGQHVTVKGFTSIMPWLAVAEKNIPQFT 1459
            YICQHFLGTLSP+CKY RI VEFESGGE F CVGQ  TVKGFTSIMPWLA++EKN+P+F 
Sbjct: 344  YICQHFLGTLSPDCKYRRIKVEFESGGEQFQCVGQLATVKGFTSIMPWLAISEKNLPEFA 403

Query: 1458 KGQKIDILRIEVEEGSTQPPDYLTESEAISLMEKNGIGTDASIPVHINNICERNYVQVQA 1279
             G+KI+I + E++EG+T PPDYLTESE ISLMEK+GIGTDASI VHINNICERNYVQVQA
Sbjct: 404  VGEKIEISKAELDEGNTSPPDYLTESELISLMEKHGIGTDASISVHINNICERNYVQVQA 463

Query: 1278 GRRLVPTALGISLIRGYQCIDPDLCLPDIRSFIEHQIALVAKGQADHSLVVQHVIEQFKR 1099
            GRRL PT LGISLIRGYQCID DLCLPDIRSFIEHQI LVAKGQADHS+VVQHV+EQF+R
Sbjct: 464  GRRLAPTPLGISLIRGYQCIDSDLCLPDIRSFIEHQITLVAKGQADHSMVVQHVLEQFRR 523

Query: 1098 KFIYFVKQIENMDALFEAEFSPLSDSGRVLSKCGKCLRYMKLISSQPSRLYCGTCEEIYY 919
            KF YFVKQI+NMDALFEA+FSPLSDSGR+LSKCGKCLRYMK IS+QP+RLYCGTCEE+YY
Sbjct: 524  KFSYFVKQIDNMDALFEAQFSPLSDSGRLLSKCGKCLRYMKYISTQPARLYCGTCEEVYY 583

Query: 918  TPPKGTIKLYKELICPLDNFELLIFSLPGPEGKSFPFCPYCYNSPPFEGIGNLYGASKTA 739
             P KGT+KLYKEL CPLDNFELL+ S+PGPEGKSFP CPYC+N PPFEGI   +GA KT 
Sbjct: 584  VPQKGTVKLYKELTCPLDNFELLLCSMPGPEGKSFPLCPYCFNCPPFEGIDTFFGAPKTG 643

Query: 738  GAVQLGKGAGMPCFLCPHPTCQHSMISQGVCACPECDGTLVLDPVSAPKWRLYCNMCNCL 559
             + +LGKG GMPCFLCPH TC HS+I+QGVCACPEC GTLVLDPVSAPKWRLYCNMCNCL
Sbjct: 644  DSTKLGKGVGMPCFLCPHTTCPHSVIAQGVCACPECSGTLVLDPVSAPKWRLYCNMCNCL 703

Query: 558  VSLPEGAHRISTTKDHCPNCDSTILEVDFNKKTTPLKDGGTLHIGCILCDELLHSLVEMK 379
            VSLPEGAHRISTT+D CP CDSTI+EVDFNKKTTPLKDG TLH GCILCDELLHSLVEMK
Sbjct: 704  VSLPEGAHRISTTQDKCPECDSTIIEVDFNKKTTPLKDGATLHKGCILCDELLHSLVEMK 763

Query: 378  HGKSF--RYXXXXXXXXXXXXXXXXRKQQDPKMSFRDF 271
            HG+SF                     KQQDPKMSFRDF
Sbjct: 764  HGRSFSRHGRRGRGRGRGRGRGRGSTKQQDPKMSFRDF 801



 Score =  243 bits (621), Expect(2) = 0.0
 Identities = 116/158 (73%), Positives = 138/158 (87%)
 Frame = -3

Query: 2116 YIIHQGYELELQWERHRLFDSDVALMFQNLVKEDGMLKVIGMSEKQESKGRPAGLNTVKL 1937
            YI+++GYEL+L+WER RLFD+DV+ MF+N + EDG++KV+ +SEK ESK RP+GLNTV L
Sbjct: 180  YIMYKGYELKLEWERSRLFDADVSAMFRNRIIEDGIMKVVRVSEKLESKARPSGLNTVNL 239

Query: 1936 LKVASSSLGFGPQLAMQLAERLYIQGFISYPRTESTAYPSSFDYKGTLGALARNSVFGDY 1757
            LKVASS+LGFGPQL MQLAERLY QGFISYPRTESTAYPSSFD+KGTLGAL  N VFG Y
Sbjct: 240  LKVASSALGFGPQLTMQLAERLYTQGFISYPRTESTAYPSSFDFKGTLGALVHNPVFGAY 299

Query: 1756 VQLLLSDGYHKPRSGNDAGDHPPITPMCSATEDMLGHD 1643
             Q LL++ Y+KPR+G DAGDHPPITPM SA+ED LG+D
Sbjct: 300  AQKLLTESYNKPRAGTDAGDHPPITPMRSASEDSLGND 337


>ref|XP_009619599.1| PREDICTED: DNA topoisomerase 3-beta isoform X1 [Nicotiana
            tomentosiformis]
          Length = 864

 Score =  780 bits (2013), Expect(2) = 0.0
 Identities = 365/462 (79%), Positives = 398/462 (86%), Gaps = 6/462 (1%)
 Frame = -1

Query: 1638 YICQHFLGTLSPECKYTRITVEFESGGESFHCVGQHVTVKGFTSIMPWLAVAEKNIPQFT 1459
            YICQHFLGTLSP+CKY RI VEFESGGE F C+GQ VTVKGFTSIMPWLAV+EKN+P F 
Sbjct: 403  YICQHFLGTLSPDCKYRRINVEFESGGEQFQCIGQLVTVKGFTSIMPWLAVSEKNLPDFA 462

Query: 1458 KGQKIDILRIEVEEGSTQPPDYLTESEAISLMEKNGIGTDASIPVHINNICERNYVQVQA 1279
            +G+KI+I +++++EG+T PPDYL ESE ISLMEK+GIGTDASI VHINNICERNYVQVQA
Sbjct: 463  EGEKIEISKVDLDEGNTSPPDYLNESELISLMEKHGIGTDASISVHINNICERNYVQVQA 522

Query: 1278 GRRLVPTALGISLIRGYQCIDPDLCLPDIRSFIEHQIALVAKGQADHSLVVQHVIEQFKR 1099
            GRRLVPT LGISLIRGYQCID DLCLPDIRSFIEHQI LVAKGQADHS+VVQHV++QF+R
Sbjct: 523  GRRLVPTPLGISLIRGYQCIDSDLCLPDIRSFIEHQITLVAKGQADHSMVVQHVLDQFRR 582

Query: 1098 KFIYFVKQIENMDALFEAEFSPLSDSGRVLSKCGKCLRYMKLISSQPSRLYCGTCEEIYY 919
            KF YFVKQIENMDALFEA+FSPLSDSGR+LSKCGKCLRYMK IS+QP RLYCGTCEE+YY
Sbjct: 583  KFSYFVKQIENMDALFEAQFSPLSDSGRLLSKCGKCLRYMKYISTQPPRLYCGTCEEVYY 642

Query: 918  TPPKGTIKLYKELICPLDNFELLIFSLPGPEGKSFPFCPYCYNSPPFEGIGNLYGASKTA 739
             P KGT+KLYKEL CPLDNFELL+  +PGPEGKSFP CPYCYN PPFEGI   +GA KT 
Sbjct: 643  VPQKGTVKLYKELTCPLDNFELLLCIMPGPEGKSFPLCPYCYNCPPFEGIDTFFGAPKTG 702

Query: 738  GAVQLGKGAGMPCFLCPHPTCQHSMISQGVCACPECDGTLVLDPVSAPKWRLYCNMCNCL 559
             + +LGKG GMPCFLCPHPTC HS+I+QGVCACPEC GTLVLDPVSAPKWRLYCNMCNCL
Sbjct: 703  DSSKLGKGVGMPCFLCPHPTCPHSVIAQGVCACPECSGTLVLDPVSAPKWRLYCNMCNCL 762

Query: 558  VSLPEGAHRISTTKDHCPNCDSTILEVDFNKKTTPLKDGGTLHIGCILCDELLHSLVEMK 379
            VSLPEGAHRISTT+D CP CDSTI+EVDFNKKTTPLKDG TLH GCILCDELLHSLVEMK
Sbjct: 763  VSLPEGAHRISTTQDKCPECDSTIIEVDFNKKTTPLKDGATLHKGCILCDELLHSLVEMK 822

Query: 378  HGKSFR------YXXXXXXXXXXXXXXXXRKQQDPKMSFRDF 271
            HG+SF                         KQQDPKMSFRDF
Sbjct: 823  HGRSFSRHGRRGRGRGKGRGGYRGRGRGNNKQQDPKMSFRDF 864



 Score =  239 bits (611), Expect(2) = 0.0
 Identities = 114/158 (72%), Positives = 136/158 (86%)
 Frame = -3

Query: 2116 YIIHQGYELELQWERHRLFDSDVALMFQNLVKEDGMLKVIGMSEKQESKGRPAGLNTVKL 1937
            YI+++GYEL+L+WER RLFD+DVA MF+N + EDG ++V+ +SEK ESKGRP+GLNTV L
Sbjct: 239  YIMYKGYELKLEWERGRLFDADVAAMFRNRLMEDGTMRVVRVSEKLESKGRPSGLNTVNL 298

Query: 1936 LKVASSSLGFGPQLAMQLAERLYIQGFISYPRTESTAYPSSFDYKGTLGALARNSVFGDY 1757
            LKVASS+LGFGPQL MQLAERLY QGF+SYPRTESTAYPSSFD+KGTL AL  N  FG Y
Sbjct: 299  LKVASSALGFGPQLTMQLAERLYTQGFVSYPRTESTAYPSSFDFKGTLVALVHNPAFGGY 358

Query: 1756 VQLLLSDGYHKPRSGNDAGDHPPITPMCSATEDMLGHD 1643
             Q LL++ Y+KPR+G DAGDHPPITPM SA+ED LG+D
Sbjct: 359  AQKLLTESYNKPRAGTDAGDHPPITPMRSASEDSLGND 396


>ref|XP_009619600.1| PREDICTED: DNA topoisomerase 3-beta isoform X2 [Nicotiana
            tomentosiformis] gi|697131091|ref|XP_009619601.1|
            PREDICTED: DNA topoisomerase 3-beta isoform X2 [Nicotiana
            tomentosiformis]
          Length = 823

 Score =  780 bits (2013), Expect(2) = 0.0
 Identities = 365/462 (79%), Positives = 398/462 (86%), Gaps = 6/462 (1%)
 Frame = -1

Query: 1638 YICQHFLGTLSPECKYTRITVEFESGGESFHCVGQHVTVKGFTSIMPWLAVAEKNIPQFT 1459
            YICQHFLGTLSP+CKY RI VEFESGGE F C+GQ VTVKGFTSIMPWLAV+EKN+P F 
Sbjct: 362  YICQHFLGTLSPDCKYRRINVEFESGGEQFQCIGQLVTVKGFTSIMPWLAVSEKNLPDFA 421

Query: 1458 KGQKIDILRIEVEEGSTQPPDYLTESEAISLMEKNGIGTDASIPVHINNICERNYVQVQA 1279
            +G+KI+I +++++EG+T PPDYL ESE ISLMEK+GIGTDASI VHINNICERNYVQVQA
Sbjct: 422  EGEKIEISKVDLDEGNTSPPDYLNESELISLMEKHGIGTDASISVHINNICERNYVQVQA 481

Query: 1278 GRRLVPTALGISLIRGYQCIDPDLCLPDIRSFIEHQIALVAKGQADHSLVVQHVIEQFKR 1099
            GRRLVPT LGISLIRGYQCID DLCLPDIRSFIEHQI LVAKGQADHS+VVQHV++QF+R
Sbjct: 482  GRRLVPTPLGISLIRGYQCIDSDLCLPDIRSFIEHQITLVAKGQADHSMVVQHVLDQFRR 541

Query: 1098 KFIYFVKQIENMDALFEAEFSPLSDSGRVLSKCGKCLRYMKLISSQPSRLYCGTCEEIYY 919
            KF YFVKQIENMDALFEA+FSPLSDSGR+LSKCGKCLRYMK IS+QP RLYCGTCEE+YY
Sbjct: 542  KFSYFVKQIENMDALFEAQFSPLSDSGRLLSKCGKCLRYMKYISTQPPRLYCGTCEEVYY 601

Query: 918  TPPKGTIKLYKELICPLDNFELLIFSLPGPEGKSFPFCPYCYNSPPFEGIGNLYGASKTA 739
             P KGT+KLYKEL CPLDNFELL+  +PGPEGKSFP CPYCYN PPFEGI   +GA KT 
Sbjct: 602  VPQKGTVKLYKELTCPLDNFELLLCIMPGPEGKSFPLCPYCYNCPPFEGIDTFFGAPKTG 661

Query: 738  GAVQLGKGAGMPCFLCPHPTCQHSMISQGVCACPECDGTLVLDPVSAPKWRLYCNMCNCL 559
             + +LGKG GMPCFLCPHPTC HS+I+QGVCACPEC GTLVLDPVSAPKWRLYCNMCNCL
Sbjct: 662  DSSKLGKGVGMPCFLCPHPTCPHSVIAQGVCACPECSGTLVLDPVSAPKWRLYCNMCNCL 721

Query: 558  VSLPEGAHRISTTKDHCPNCDSTILEVDFNKKTTPLKDGGTLHIGCILCDELLHSLVEMK 379
            VSLPEGAHRISTT+D CP CDSTI+EVDFNKKTTPLKDG TLH GCILCDELLHSLVEMK
Sbjct: 722  VSLPEGAHRISTTQDKCPECDSTIIEVDFNKKTTPLKDGATLHKGCILCDELLHSLVEMK 781

Query: 378  HGKSFR------YXXXXXXXXXXXXXXXXRKQQDPKMSFRDF 271
            HG+SF                         KQQDPKMSFRDF
Sbjct: 782  HGRSFSRHGRRGRGRGKGRGGYRGRGRGNNKQQDPKMSFRDF 823



 Score =  239 bits (611), Expect(2) = 0.0
 Identities = 114/158 (72%), Positives = 136/158 (86%)
 Frame = -3

Query: 2116 YIIHQGYELELQWERHRLFDSDVALMFQNLVKEDGMLKVIGMSEKQESKGRPAGLNTVKL 1937
            YI+++GYEL+L+WER RLFD+DVA MF+N + EDG ++V+ +SEK ESKGRP+GLNTV L
Sbjct: 198  YIMYKGYELKLEWERGRLFDADVAAMFRNRLMEDGTMRVVRVSEKLESKGRPSGLNTVNL 257

Query: 1936 LKVASSSLGFGPQLAMQLAERLYIQGFISYPRTESTAYPSSFDYKGTLGALARNSVFGDY 1757
            LKVASS+LGFGPQL MQLAERLY QGF+SYPRTESTAYPSSFD+KGTL AL  N  FG Y
Sbjct: 258  LKVASSALGFGPQLTMQLAERLYTQGFVSYPRTESTAYPSSFDFKGTLVALVHNPAFGGY 317

Query: 1756 VQLLLSDGYHKPRSGNDAGDHPPITPMCSATEDMLGHD 1643
             Q LL++ Y+KPR+G DAGDHPPITPM SA+ED LG+D
Sbjct: 318  AQKLLTESYNKPRAGTDAGDHPPITPMRSASEDSLGND 355


>ref|XP_009619602.1| PREDICTED: DNA topoisomerase 3-beta isoform X3 [Nicotiana
            tomentosiformis]
          Length = 805

 Score =  780 bits (2013), Expect(2) = 0.0
 Identities = 365/462 (79%), Positives = 398/462 (86%), Gaps = 6/462 (1%)
 Frame = -1

Query: 1638 YICQHFLGTLSPECKYTRITVEFESGGESFHCVGQHVTVKGFTSIMPWLAVAEKNIPQFT 1459
            YICQHFLGTLSP+CKY RI VEFESGGE F C+GQ VTVKGFTSIMPWLAV+EKN+P F 
Sbjct: 344  YICQHFLGTLSPDCKYRRINVEFESGGEQFQCIGQLVTVKGFTSIMPWLAVSEKNLPDFA 403

Query: 1458 KGQKIDILRIEVEEGSTQPPDYLTESEAISLMEKNGIGTDASIPVHINNICERNYVQVQA 1279
            +G+KI+I +++++EG+T PPDYL ESE ISLMEK+GIGTDASI VHINNICERNYVQVQA
Sbjct: 404  EGEKIEISKVDLDEGNTSPPDYLNESELISLMEKHGIGTDASISVHINNICERNYVQVQA 463

Query: 1278 GRRLVPTALGISLIRGYQCIDPDLCLPDIRSFIEHQIALVAKGQADHSLVVQHVIEQFKR 1099
            GRRLVPT LGISLIRGYQCID DLCLPDIRSFIEHQI LVAKGQADHS+VVQHV++QF+R
Sbjct: 464  GRRLVPTPLGISLIRGYQCIDSDLCLPDIRSFIEHQITLVAKGQADHSMVVQHVLDQFRR 523

Query: 1098 KFIYFVKQIENMDALFEAEFSPLSDSGRVLSKCGKCLRYMKLISSQPSRLYCGTCEEIYY 919
            KF YFVKQIENMDALFEA+FSPLSDSGR+LSKCGKCLRYMK IS+QP RLYCGTCEE+YY
Sbjct: 524  KFSYFVKQIENMDALFEAQFSPLSDSGRLLSKCGKCLRYMKYISTQPPRLYCGTCEEVYY 583

Query: 918  TPPKGTIKLYKELICPLDNFELLIFSLPGPEGKSFPFCPYCYNSPPFEGIGNLYGASKTA 739
             P KGT+KLYKEL CPLDNFELL+  +PGPEGKSFP CPYCYN PPFEGI   +GA KT 
Sbjct: 584  VPQKGTVKLYKELTCPLDNFELLLCIMPGPEGKSFPLCPYCYNCPPFEGIDTFFGAPKTG 643

Query: 738  GAVQLGKGAGMPCFLCPHPTCQHSMISQGVCACPECDGTLVLDPVSAPKWRLYCNMCNCL 559
             + +LGKG GMPCFLCPHPTC HS+I+QGVCACPEC GTLVLDPVSAPKWRLYCNMCNCL
Sbjct: 644  DSSKLGKGVGMPCFLCPHPTCPHSVIAQGVCACPECSGTLVLDPVSAPKWRLYCNMCNCL 703

Query: 558  VSLPEGAHRISTTKDHCPNCDSTILEVDFNKKTTPLKDGGTLHIGCILCDELLHSLVEMK 379
            VSLPEGAHRISTT+D CP CDSTI+EVDFNKKTTPLKDG TLH GCILCDELLHSLVEMK
Sbjct: 704  VSLPEGAHRISTTQDKCPECDSTIIEVDFNKKTTPLKDGATLHKGCILCDELLHSLVEMK 763

Query: 378  HGKSFR------YXXXXXXXXXXXXXXXXRKQQDPKMSFRDF 271
            HG+SF                         KQQDPKMSFRDF
Sbjct: 764  HGRSFSRHGRRGRGRGKGRGGYRGRGRGNNKQQDPKMSFRDF 805



 Score =  239 bits (611), Expect(2) = 0.0
 Identities = 114/158 (72%), Positives = 136/158 (86%)
 Frame = -3

Query: 2116 YIIHQGYELELQWERHRLFDSDVALMFQNLVKEDGMLKVIGMSEKQESKGRPAGLNTVKL 1937
            YI+++GYEL+L+WER RLFD+DVA MF+N + EDG ++V+ +SEK ESKGRP+GLNTV L
Sbjct: 180  YIMYKGYELKLEWERGRLFDADVAAMFRNRLMEDGTMRVVRVSEKLESKGRPSGLNTVNL 239

Query: 1936 LKVASSSLGFGPQLAMQLAERLYIQGFISYPRTESTAYPSSFDYKGTLGALARNSVFGDY 1757
            LKVASS+LGFGPQL MQLAERLY QGF+SYPRTESTAYPSSFD+KGTL AL  N  FG Y
Sbjct: 240  LKVASSALGFGPQLTMQLAERLYTQGFVSYPRTESTAYPSSFDFKGTLVALVHNPAFGGY 299

Query: 1756 VQLLLSDGYHKPRSGNDAGDHPPITPMCSATEDMLGHD 1643
             Q LL++ Y+KPR+G DAGDHPPITPM SA+ED LG+D
Sbjct: 300  AQKLLTESYNKPRAGTDAGDHPPITPMRSASEDSLGND 337


>ref|XP_009765587.1| PREDICTED: DNA topoisomerase 3-beta isoform X1 [Nicotiana sylvestris]
          Length = 864

 Score =  777 bits (2006), Expect(2) = 0.0
 Identities = 363/462 (78%), Positives = 399/462 (86%), Gaps = 6/462 (1%)
 Frame = -1

Query: 1638 YICQHFLGTLSPECKYTRITVEFESGGESFHCVGQHVTVKGFTSIMPWLAVAEKNIPQFT 1459
            YICQHFLGTLSP+C+Y RI VEFESGGE F C+GQ VTVKGFTSIMPWLA++EKN+P F 
Sbjct: 403  YICQHFLGTLSPDCRYRRIKVEFESGGEQFQCIGQLVTVKGFTSIMPWLAISEKNLPDFA 462

Query: 1458 KGQKIDILRIEVEEGSTQPPDYLTESEAISLMEKNGIGTDASIPVHINNICERNYVQVQA 1279
            +G+KI+I +++++EG+T PPDYL ESE ISLMEK+GIGTDASI VHINNICERNYVQVQA
Sbjct: 463  EGEKIEISKVDLDEGNTSPPDYLNESELISLMEKHGIGTDASISVHINNICERNYVQVQA 522

Query: 1278 GRRLVPTALGISLIRGYQCIDPDLCLPDIRSFIEHQIALVAKGQADHSLVVQHVIEQFKR 1099
            GRRLVPT LGISLIRGYQCID DLCLPDIRSFIEHQI LVAKGQADHS+VVQHV++QF+R
Sbjct: 523  GRRLVPTPLGISLIRGYQCIDSDLCLPDIRSFIEHQITLVAKGQADHSMVVQHVLDQFRR 582

Query: 1098 KFIYFVKQIENMDALFEAEFSPLSDSGRVLSKCGKCLRYMKLISSQPSRLYCGTCEEIYY 919
            KF YFVKQIENMDALFEA+FSPLSDSGR+LSKCGKCLRYMK IS+QPSRLYCGTCEE+YY
Sbjct: 583  KFSYFVKQIENMDALFEAQFSPLSDSGRLLSKCGKCLRYMKYISTQPSRLYCGTCEEVYY 642

Query: 918  TPPKGTIKLYKELICPLDNFELLIFSLPGPEGKSFPFCPYCYNSPPFEGIGNLYGASKTA 739
             P KGT+KLYKEL CPLDNFELL+ S+PGPEGKSFP CPYCYN PPFEGI   +GA KT 
Sbjct: 643  VPQKGTVKLYKELTCPLDNFELLLCSMPGPEGKSFPLCPYCYNCPPFEGIDTFFGAPKTG 702

Query: 738  GAVQLGKGAGMPCFLCPHPTCQHSMISQGVCACPECDGTLVLDPVSAPKWRLYCNMCNCL 559
             + +LGKG GMPCFLCPHPTC HS+I+QGVCACPEC GTLVLDPVSAPKWRL CNMCNCL
Sbjct: 703  DSSKLGKGVGMPCFLCPHPTCPHSVIAQGVCACPECSGTLVLDPVSAPKWRLCCNMCNCL 762

Query: 558  VSLPEGAHRISTTKDHCPNCDSTILEVDFNKKTTPLKDGGTLHIGCILCDELLHSLVEMK 379
            VSLPEGAHRISTT+D CP C+STI+EVDFNKKTTPLKDG TLH GCILCDELLHSLVEMK
Sbjct: 763  VSLPEGAHRISTTQDKCPECESTIIEVDFNKKTTPLKDGATLHKGCILCDELLHSLVEMK 822

Query: 378  HGKSFR------YXXXXXXXXXXXXXXXXRKQQDPKMSFRDF 271
            HG+SF                         KQQDPKMSFRDF
Sbjct: 823  HGRSFSRHGRSGRGRGKGRGGYRGRGRGNNKQQDPKMSFRDF 864



 Score =  239 bits (611), Expect(2) = 0.0
 Identities = 115/158 (72%), Positives = 136/158 (86%)
 Frame = -3

Query: 2116 YIIHQGYELELQWERHRLFDSDVALMFQNLVKEDGMLKVIGMSEKQESKGRPAGLNTVKL 1937
            YI+++GYEL+L+WER RLFD+DVA MF+N + EDG ++V+ +SEK ESKGRP+GLNTV L
Sbjct: 239  YIMYKGYELKLEWERGRLFDADVAAMFRNRLMEDGTMRVVRVSEKLESKGRPSGLNTVNL 298

Query: 1936 LKVASSSLGFGPQLAMQLAERLYIQGFISYPRTESTAYPSSFDYKGTLGALARNSVFGDY 1757
            LKVASS+LGFGPQL MQLAERLY QGFISYPRTESTAYPSSFD++GTL AL  N VFG Y
Sbjct: 299  LKVASSALGFGPQLTMQLAERLYTQGFISYPRTESTAYPSSFDFRGTLVALVHNPVFGGY 358

Query: 1756 VQLLLSDGYHKPRSGNDAGDHPPITPMCSATEDMLGHD 1643
             Q LL++ Y+KPR+G DAGDHPPITPM SA ED LG+D
Sbjct: 359  AQKLLTESYNKPRAGTDAGDHPPITPMRSAIEDSLGND 396


>ref|XP_009765588.1| PREDICTED: DNA topoisomerase 3-beta isoform X2 [Nicotiana sylvestris]
          Length = 815

 Score =  777 bits (2006), Expect(2) = 0.0
 Identities = 363/462 (78%), Positives = 399/462 (86%), Gaps = 6/462 (1%)
 Frame = -1

Query: 1638 YICQHFLGTLSPECKYTRITVEFESGGESFHCVGQHVTVKGFTSIMPWLAVAEKNIPQFT 1459
            YICQHFLGTLSP+C+Y RI VEFESGGE F C+GQ VTVKGFTSIMPWLA++EKN+P F 
Sbjct: 354  YICQHFLGTLSPDCRYRRIKVEFESGGEQFQCIGQLVTVKGFTSIMPWLAISEKNLPDFA 413

Query: 1458 KGQKIDILRIEVEEGSTQPPDYLTESEAISLMEKNGIGTDASIPVHINNICERNYVQVQA 1279
            +G+KI+I +++++EG+T PPDYL ESE ISLMEK+GIGTDASI VHINNICERNYVQVQA
Sbjct: 414  EGEKIEISKVDLDEGNTSPPDYLNESELISLMEKHGIGTDASISVHINNICERNYVQVQA 473

Query: 1278 GRRLVPTALGISLIRGYQCIDPDLCLPDIRSFIEHQIALVAKGQADHSLVVQHVIEQFKR 1099
            GRRLVPT LGISLIRGYQCID DLCLPDIRSFIEHQI LVAKGQADHS+VVQHV++QF+R
Sbjct: 474  GRRLVPTPLGISLIRGYQCIDSDLCLPDIRSFIEHQITLVAKGQADHSMVVQHVLDQFRR 533

Query: 1098 KFIYFVKQIENMDALFEAEFSPLSDSGRVLSKCGKCLRYMKLISSQPSRLYCGTCEEIYY 919
            KF YFVKQIENMDALFEA+FSPLSDSGR+LSKCGKCLRYMK IS+QPSRLYCGTCEE+YY
Sbjct: 534  KFSYFVKQIENMDALFEAQFSPLSDSGRLLSKCGKCLRYMKYISTQPSRLYCGTCEEVYY 593

Query: 918  TPPKGTIKLYKELICPLDNFELLIFSLPGPEGKSFPFCPYCYNSPPFEGIGNLYGASKTA 739
             P KGT+KLYKEL CPLDNFELL+ S+PGPEGKSFP CPYCYN PPFEGI   +GA KT 
Sbjct: 594  VPQKGTVKLYKELTCPLDNFELLLCSMPGPEGKSFPLCPYCYNCPPFEGIDTFFGAPKTG 653

Query: 738  GAVQLGKGAGMPCFLCPHPTCQHSMISQGVCACPECDGTLVLDPVSAPKWRLYCNMCNCL 559
             + +LGKG GMPCFLCPHPTC HS+I+QGVCACPEC GTLVLDPVSAPKWRL CNMCNCL
Sbjct: 654  DSSKLGKGVGMPCFLCPHPTCPHSVIAQGVCACPECSGTLVLDPVSAPKWRLCCNMCNCL 713

Query: 558  VSLPEGAHRISTTKDHCPNCDSTILEVDFNKKTTPLKDGGTLHIGCILCDELLHSLVEMK 379
            VSLPEGAHRISTT+D CP C+STI+EVDFNKKTTPLKDG TLH GCILCDELLHSLVEMK
Sbjct: 714  VSLPEGAHRISTTQDKCPECESTIIEVDFNKKTTPLKDGATLHKGCILCDELLHSLVEMK 773

Query: 378  HGKSFR------YXXXXXXXXXXXXXXXXRKQQDPKMSFRDF 271
            HG+SF                         KQQDPKMSFRDF
Sbjct: 774  HGRSFSRHGRSGRGRGKGRGGYRGRGRGNNKQQDPKMSFRDF 815



 Score =  239 bits (611), Expect(2) = 0.0
 Identities = 115/158 (72%), Positives = 136/158 (86%)
 Frame = -3

Query: 2116 YIIHQGYELELQWERHRLFDSDVALMFQNLVKEDGMLKVIGMSEKQESKGRPAGLNTVKL 1937
            YI+++GYEL+L+WER RLFD+DVA MF+N + EDG ++V+ +SEK ESKGRP+GLNTV L
Sbjct: 190  YIMYKGYELKLEWERGRLFDADVAAMFRNRLMEDGTMRVVRVSEKLESKGRPSGLNTVNL 249

Query: 1936 LKVASSSLGFGPQLAMQLAERLYIQGFISYPRTESTAYPSSFDYKGTLGALARNSVFGDY 1757
            LKVASS+LGFGPQL MQLAERLY QGFISYPRTESTAYPSSFD++GTL AL  N VFG Y
Sbjct: 250  LKVASSALGFGPQLTMQLAERLYTQGFISYPRTESTAYPSSFDFRGTLVALVHNPVFGGY 309

Query: 1756 VQLLLSDGYHKPRSGNDAGDHPPITPMCSATEDMLGHD 1643
             Q LL++ Y+KPR+G DAGDHPPITPM SA ED LG+D
Sbjct: 310  AQKLLTESYNKPRAGTDAGDHPPITPMRSAIEDSLGND 347


>ref|XP_009765589.1| PREDICTED: DNA topoisomerase 3-beta isoform X3 [Nicotiana sylvestris]
          Length = 805

 Score =  777 bits (2006), Expect(2) = 0.0
 Identities = 363/462 (78%), Positives = 399/462 (86%), Gaps = 6/462 (1%)
 Frame = -1

Query: 1638 YICQHFLGTLSPECKYTRITVEFESGGESFHCVGQHVTVKGFTSIMPWLAVAEKNIPQFT 1459
            YICQHFLGTLSP+C+Y RI VEFESGGE F C+GQ VTVKGFTSIMPWLA++EKN+P F 
Sbjct: 344  YICQHFLGTLSPDCRYRRIKVEFESGGEQFQCIGQLVTVKGFTSIMPWLAISEKNLPDFA 403

Query: 1458 KGQKIDILRIEVEEGSTQPPDYLTESEAISLMEKNGIGTDASIPVHINNICERNYVQVQA 1279
            +G+KI+I +++++EG+T PPDYL ESE ISLMEK+GIGTDASI VHINNICERNYVQVQA
Sbjct: 404  EGEKIEISKVDLDEGNTSPPDYLNESELISLMEKHGIGTDASISVHINNICERNYVQVQA 463

Query: 1278 GRRLVPTALGISLIRGYQCIDPDLCLPDIRSFIEHQIALVAKGQADHSLVVQHVIEQFKR 1099
            GRRLVPT LGISLIRGYQCID DLCLPDIRSFIEHQI LVAKGQADHS+VVQHV++QF+R
Sbjct: 464  GRRLVPTPLGISLIRGYQCIDSDLCLPDIRSFIEHQITLVAKGQADHSMVVQHVLDQFRR 523

Query: 1098 KFIYFVKQIENMDALFEAEFSPLSDSGRVLSKCGKCLRYMKLISSQPSRLYCGTCEEIYY 919
            KF YFVKQIENMDALFEA+FSPLSDSGR+LSKCGKCLRYMK IS+QPSRLYCGTCEE+YY
Sbjct: 524  KFSYFVKQIENMDALFEAQFSPLSDSGRLLSKCGKCLRYMKYISTQPSRLYCGTCEEVYY 583

Query: 918  TPPKGTIKLYKELICPLDNFELLIFSLPGPEGKSFPFCPYCYNSPPFEGIGNLYGASKTA 739
             P KGT+KLYKEL CPLDNFELL+ S+PGPEGKSFP CPYCYN PPFEGI   +GA KT 
Sbjct: 584  VPQKGTVKLYKELTCPLDNFELLLCSMPGPEGKSFPLCPYCYNCPPFEGIDTFFGAPKTG 643

Query: 738  GAVQLGKGAGMPCFLCPHPTCQHSMISQGVCACPECDGTLVLDPVSAPKWRLYCNMCNCL 559
             + +LGKG GMPCFLCPHPTC HS+I+QGVCACPEC GTLVLDPVSAPKWRL CNMCNCL
Sbjct: 644  DSSKLGKGVGMPCFLCPHPTCPHSVIAQGVCACPECSGTLVLDPVSAPKWRLCCNMCNCL 703

Query: 558  VSLPEGAHRISTTKDHCPNCDSTILEVDFNKKTTPLKDGGTLHIGCILCDELLHSLVEMK 379
            VSLPEGAHRISTT+D CP C+STI+EVDFNKKTTPLKDG TLH GCILCDELLHSLVEMK
Sbjct: 704  VSLPEGAHRISTTQDKCPECESTIIEVDFNKKTTPLKDGATLHKGCILCDELLHSLVEMK 763

Query: 378  HGKSFR------YXXXXXXXXXXXXXXXXRKQQDPKMSFRDF 271
            HG+SF                         KQQDPKMSFRDF
Sbjct: 764  HGRSFSRHGRSGRGRGKGRGGYRGRGRGNNKQQDPKMSFRDF 805



 Score =  239 bits (611), Expect(2) = 0.0
 Identities = 115/158 (72%), Positives = 136/158 (86%)
 Frame = -3

Query: 2116 YIIHQGYELELQWERHRLFDSDVALMFQNLVKEDGMLKVIGMSEKQESKGRPAGLNTVKL 1937
            YI+++GYEL+L+WER RLFD+DVA MF+N + EDG ++V+ +SEK ESKGRP+GLNTV L
Sbjct: 180  YIMYKGYELKLEWERGRLFDADVAAMFRNRLMEDGTMRVVRVSEKLESKGRPSGLNTVNL 239

Query: 1936 LKVASSSLGFGPQLAMQLAERLYIQGFISYPRTESTAYPSSFDYKGTLGALARNSVFGDY 1757
            LKVASS+LGFGPQL MQLAERLY QGFISYPRTESTAYPSSFD++GTL AL  N VFG Y
Sbjct: 240  LKVASSALGFGPQLTMQLAERLYTQGFISYPRTESTAYPSSFDFRGTLVALVHNPVFGGY 299

Query: 1756 VQLLLSDGYHKPRSGNDAGDHPPITPMCSATEDMLGHD 1643
             Q LL++ Y+KPR+G DAGDHPPITPM SA ED LG+D
Sbjct: 300  AQKLLTESYNKPRAGTDAGDHPPITPMRSAIEDSLGND 337


>ref|XP_007034151.1| DNA topoisomerase, type IA, core [Theobroma cacao]
            gi|508713180|gb|EOY05077.1| DNA topoisomerase, type IA,
            core [Theobroma cacao]
          Length = 868

 Score =  757 bits (1954), Expect(2) = 0.0
 Identities = 349/463 (75%), Positives = 395/463 (85%), Gaps = 7/463 (1%)
 Frame = -1

Query: 1638 YICQHFLGTLSPECKYTRITVEFESGGESFHCVGQHVTVKGFTSIMPWLAVAEKNIPQFT 1459
            Y+CQHF+GT+SP+CKY R  VEF  GGE FHC+GQHVT +GFT IMPWLA+ EKN+PQFT
Sbjct: 406  YVCQHFIGTVSPDCKYVRRKVEFLVGGEYFHCIGQHVTAQGFTYIMPWLAINEKNLPQFT 465

Query: 1458 KGQKIDILRIEVEEGSTQPPDYLTESEAISLMEKNGIGTDASIPVHINNICERNYVQVQA 1279
            KG+KI++ ++E+ EG T PPDYL+ESE ISLME+N IGTDASIPVHINNICERNYVQVQ 
Sbjct: 466  KGEKIEVSKVELYEGETSPPDYLSESELISLMERNRIGTDASIPVHINNICERNYVQVQG 525

Query: 1278 GRRLVPTALGISLIRGYQCIDPDLCLPDIRSFIEHQIALVAKGQADHSLVVQHVIEQFKR 1099
            GR+LVPTALGI+LIRGYQCIDPDLCLPDIRSFIEHQI LVAKGQA+HS VVQHV++QFK+
Sbjct: 526  GRKLVPTALGITLIRGYQCIDPDLCLPDIRSFIEHQITLVAKGQANHSHVVQHVLQQFKQ 585

Query: 1098 KFIYFVKQIENMDALFEAEFSPLSDSGRVLSKCGKCLRYMKLISSQPSRLYCGTCEEIYY 919
            KF YFV+QIENMDALFEA+FSPL+DSGR LSKCGKCLRYMK IS+QP RL+CGTCEE+Y+
Sbjct: 586  KFSYFVQQIENMDALFEAQFSPLADSGRALSKCGKCLRYMKYISTQPPRLFCGTCEEVYH 645

Query: 918  TPPKGTIKLYKELICPLDNFELLIFSLPGPEGKSFPFCPYCYNSPPFEGIGNLYGASKTA 739
             P KGTIKLYKEL CPLDNFELLIFS+PGPEGKSFP CPYCYNSPPFEG+  L+GA++  
Sbjct: 646  LPQKGTIKLYKELTCPLDNFELLIFSMPGPEGKSFPLCPYCYNSPPFEGMDTLFGATRIG 705

Query: 738  GAVQLGKGAGMPCFLCPHPTCQHSMISQGVCACPECDGTLVLDPVSAPKWRLYCNMCNCL 559
             + +LGKGAGMPCFLCPHPTC+HS+++QGVCACPEC GTLVLDPVSAPKWRLYCN CNCL
Sbjct: 706  SSGKLGKGAGMPCFLCPHPTCRHSVVAQGVCACPECSGTLVLDPVSAPKWRLYCNKCNCL 765

Query: 558  VSLPEGAHRISTTKDHCPNCDSTILEVDFNKKTTPLKDGGTLHIGCILCDELLHSLVEMK 379
            V LPEGAHRI+TT++ C  CDSTI+EVDFNKKTTPL+DG TLH GCILCDELLHS VE+K
Sbjct: 766  VLLPEGAHRIATTRERCAECDSTIIEVDFNKKTTPLEDGATLHTGCILCDELLHSFVEVK 825

Query: 378  HGKSFR-------YXXXXXXXXXXXXXXXXRKQQDPKMSFRDF 271
            HGKSF                          KQ DPKMSFRDF
Sbjct: 826  HGKSFSRGLGGRGRGRGTRRGGYRGRGRAAGKQVDPKMSFRDF 868



 Score =  256 bits (653), Expect(2) = 0.0
 Identities = 122/158 (77%), Positives = 141/158 (89%)
 Frame = -3

Query: 2116 YIIHQGYELELQWERHRLFDSDVALMFQNLVKEDGMLKVIGMSEKQESKGRPAGLNTVKL 1937
            YII  GY+L+L+W+R +LFD DVA+MFQ LV EDG+L+VI +SEKQESKGRP+GLNTV L
Sbjct: 242  YIIQNGYDLQLEWKRQKLFDIDVAIMFQKLVTEDGILEVIDVSEKQESKGRPSGLNTVNL 301

Query: 1936 LKVASSSLGFGPQLAMQLAERLYIQGFISYPRTESTAYPSSFDYKGTLGALARNSVFGDY 1757
            LKVASS+LGFGPQ AMQLAERLY QGFISYPRTESTAYP+SFD+KGTL  +A NS++GDY
Sbjct: 302  LKVASSALGFGPQTAMQLAERLYTQGFISYPRTESTAYPASFDFKGTLNVIANNSLWGDY 361

Query: 1756 VQLLLSDGYHKPRSGNDAGDHPPITPMCSATEDMLGHD 1643
            VQ LL++GYHKPRSG DAGDHPPITPM SATED+LG D
Sbjct: 362  VQRLLAEGYHKPRSGTDAGDHPPITPMHSATEDILGKD 399


>ref|XP_004248022.1| PREDICTED: DNA topoisomerase 3-beta isoform X1 [Solanum lycopersicum]
          Length = 864

 Score =  769 bits (1986), Expect(2) = 0.0
 Identities = 359/462 (77%), Positives = 395/462 (85%), Gaps = 6/462 (1%)
 Frame = -1

Query: 1638 YICQHFLGTLSPECKYTRITVEFESGGESFHCVGQHVTVKGFTSIMPWLAVAEKNIPQFT 1459
            YICQHFLGTLSP+CKY RI VEFESGGE F CVGQ  TVKGFTSIMPWLA++EKN+P+F 
Sbjct: 403  YICQHFLGTLSPDCKYRRIKVEFESGGEQFQCVGQLATVKGFTSIMPWLAISEKNLPEFA 462

Query: 1458 KGQKIDILRIEVEEGSTQPPDYLTESEAISLMEKNGIGTDASIPVHINNICERNYVQVQA 1279
             G+KI++ ++E++EG T PP YL+ESE ISLMEK+GIGTDASI VHINNICERNYVQVQA
Sbjct: 463  VGEKIEVSKVELDEGDTSPPGYLSESELISLMEKHGIGTDASISVHINNICERNYVQVQA 522

Query: 1278 GRRLVPTALGISLIRGYQCIDPDLCLPDIRSFIEHQIALVAKGQADHSLVVQHVIEQFKR 1099
            GRRL PT LGISLIRGYQCID DLCLPDIRSFIEHQI LVAKGQADHS+VVQHV+EQF+R
Sbjct: 523  GRRLAPTPLGISLIRGYQCIDSDLCLPDIRSFIEHQITLVAKGQADHSMVVQHVLEQFRR 582

Query: 1098 KFIYFVKQIENMDALFEAEFSPLSDSGRVLSKCGKCLRYMKLISSQPSRLYCGTCEEIYY 919
            KF YFVKQI+NMDALFEA+FSPLSDSGR+LSKCGKCLRYMK IS+QP+RLYCGTCEE+YY
Sbjct: 583  KFSYFVKQIDNMDALFEAQFSPLSDSGRLLSKCGKCLRYMKYISTQPARLYCGTCEEVYY 642

Query: 918  TPPKGTIKLYKELICPLDNFELLIFSLPGPEGKSFPFCPYCYNSPPFEGIGNLYGASKTA 739
             P KGT+KLYKEL CPLDNFELL+ S+PGPEGKSFP CPYC+N PPFEGI   +GA KT 
Sbjct: 643  VPQKGTVKLYKELTCPLDNFELLLCSMPGPEGKSFPLCPYCFNCPPFEGIDTFFGAPKTG 702

Query: 738  GAVQLGKGAGMPCFLCPHPTCQHSMISQGVCACPECDGTLVLDPVSAPKWRLYCNMCNCL 559
             + +LGKG GMPCFLCPH TC HS+I+QGVCACPEC GTLVLDPVSAPKWRLYCN CNCL
Sbjct: 703  DSTKLGKGVGMPCFLCPHTTCPHSVIAQGVCACPECSGTLVLDPVSAPKWRLYCNTCNCL 762

Query: 558  VSLPEGAHRISTTKDHCPNCDSTILEVDFNKKTTPLKDGGTLHIGCILCDELLHSLVEMK 379
            VSLPEGAHRISTT++ CP CDSTI+EVDFNKKTTPLKDG TLH GCILCDELLHSLVEMK
Sbjct: 763  VSLPEGAHRISTTQEKCPECDSTIIEVDFNKKTTPLKDGATLHKGCILCDELLHSLVEMK 822

Query: 378  HGKSFR------YXXXXXXXXXXXXXXXXRKQQDPKMSFRDF 271
            HG+SF                         KQQDPKMSFRDF
Sbjct: 823  HGRSFSRHGRRGRGRGRGRGGYRGRGRGSNKQQDPKMSFRDF 864



 Score =  240 bits (613), Expect(2) = 0.0
 Identities = 116/158 (73%), Positives = 136/158 (86%)
 Frame = -3

Query: 2116 YIIHQGYELELQWERHRLFDSDVALMFQNLVKEDGMLKVIGMSEKQESKGRPAGLNTVKL 1937
            YI+++GYEL+L+WER RLFD+DV+ MF+N + ED ++KV+ +SEK ESK RP+GLNTV L
Sbjct: 239  YIMYKGYELKLEWERSRLFDADVSAMFRNRIIEDRIMKVVRVSEKLESKARPSGLNTVNL 298

Query: 1936 LKVASSSLGFGPQLAMQLAERLYIQGFISYPRTESTAYPSSFDYKGTLGALARNSVFGDY 1757
            LKVASS+LGFGPQL MQLAERLY QGFISYPRTESTAYPSSFD+KGTLGAL  N VFG Y
Sbjct: 299  LKVASSALGFGPQLTMQLAERLYTQGFISYPRTESTAYPSSFDFKGTLGALVHNPVFGAY 358

Query: 1756 VQLLLSDGYHKPRSGNDAGDHPPITPMCSATEDMLGHD 1643
             Q LL+D Y KPR+G DAGDHPPITPM SA+ED LG+D
Sbjct: 359  AQKLLTDNYIKPRAGTDAGDHPPITPMRSASEDSLGND 396


>ref|XP_010326952.1| PREDICTED: DNA topoisomerase 3-beta isoform X2 [Solanum lycopersicum]
          Length = 805

 Score =  769 bits (1986), Expect(2) = 0.0
 Identities = 359/462 (77%), Positives = 395/462 (85%), Gaps = 6/462 (1%)
 Frame = -1

Query: 1638 YICQHFLGTLSPECKYTRITVEFESGGESFHCVGQHVTVKGFTSIMPWLAVAEKNIPQFT 1459
            YICQHFLGTLSP+CKY RI VEFESGGE F CVGQ  TVKGFTSIMPWLA++EKN+P+F 
Sbjct: 344  YICQHFLGTLSPDCKYRRIKVEFESGGEQFQCVGQLATVKGFTSIMPWLAISEKNLPEFA 403

Query: 1458 KGQKIDILRIEVEEGSTQPPDYLTESEAISLMEKNGIGTDASIPVHINNICERNYVQVQA 1279
             G+KI++ ++E++EG T PP YL+ESE ISLMEK+GIGTDASI VHINNICERNYVQVQA
Sbjct: 404  VGEKIEVSKVELDEGDTSPPGYLSESELISLMEKHGIGTDASISVHINNICERNYVQVQA 463

Query: 1278 GRRLVPTALGISLIRGYQCIDPDLCLPDIRSFIEHQIALVAKGQADHSLVVQHVIEQFKR 1099
            GRRL PT LGISLIRGYQCID DLCLPDIRSFIEHQI LVAKGQADHS+VVQHV+EQF+R
Sbjct: 464  GRRLAPTPLGISLIRGYQCIDSDLCLPDIRSFIEHQITLVAKGQADHSMVVQHVLEQFRR 523

Query: 1098 KFIYFVKQIENMDALFEAEFSPLSDSGRVLSKCGKCLRYMKLISSQPSRLYCGTCEEIYY 919
            KF YFVKQI+NMDALFEA+FSPLSDSGR+LSKCGKCLRYMK IS+QP+RLYCGTCEE+YY
Sbjct: 524  KFSYFVKQIDNMDALFEAQFSPLSDSGRLLSKCGKCLRYMKYISTQPARLYCGTCEEVYY 583

Query: 918  TPPKGTIKLYKELICPLDNFELLIFSLPGPEGKSFPFCPYCYNSPPFEGIGNLYGASKTA 739
             P KGT+KLYKEL CPLDNFELL+ S+PGPEGKSFP CPYC+N PPFEGI   +GA KT 
Sbjct: 584  VPQKGTVKLYKELTCPLDNFELLLCSMPGPEGKSFPLCPYCFNCPPFEGIDTFFGAPKTG 643

Query: 738  GAVQLGKGAGMPCFLCPHPTCQHSMISQGVCACPECDGTLVLDPVSAPKWRLYCNMCNCL 559
             + +LGKG GMPCFLCPH TC HS+I+QGVCACPEC GTLVLDPVSAPKWRLYCN CNCL
Sbjct: 644  DSTKLGKGVGMPCFLCPHTTCPHSVIAQGVCACPECSGTLVLDPVSAPKWRLYCNTCNCL 703

Query: 558  VSLPEGAHRISTTKDHCPNCDSTILEVDFNKKTTPLKDGGTLHIGCILCDELLHSLVEMK 379
            VSLPEGAHRISTT++ CP CDSTI+EVDFNKKTTPLKDG TLH GCILCDELLHSLVEMK
Sbjct: 704  VSLPEGAHRISTTQEKCPECDSTIIEVDFNKKTTPLKDGATLHKGCILCDELLHSLVEMK 763

Query: 378  HGKSFR------YXXXXXXXXXXXXXXXXRKQQDPKMSFRDF 271
            HG+SF                         KQQDPKMSFRDF
Sbjct: 764  HGRSFSRHGRRGRGRGRGRGGYRGRGRGSNKQQDPKMSFRDF 805



 Score =  240 bits (613), Expect(2) = 0.0
 Identities = 116/158 (73%), Positives = 136/158 (86%)
 Frame = -3

Query: 2116 YIIHQGYELELQWERHRLFDSDVALMFQNLVKEDGMLKVIGMSEKQESKGRPAGLNTVKL 1937
            YI+++GYEL+L+WER RLFD+DV+ MF+N + ED ++KV+ +SEK ESK RP+GLNTV L
Sbjct: 180  YIMYKGYELKLEWERSRLFDADVSAMFRNRIIEDRIMKVVRVSEKLESKARPSGLNTVNL 239

Query: 1936 LKVASSSLGFGPQLAMQLAERLYIQGFISYPRTESTAYPSSFDYKGTLGALARNSVFGDY 1757
            LKVASS+LGFGPQL MQLAERLY QGFISYPRTESTAYPSSFD+KGTLGAL  N VFG Y
Sbjct: 240  LKVASSALGFGPQLTMQLAERLYTQGFISYPRTESTAYPSSFDFKGTLGALVHNPVFGAY 299

Query: 1756 VQLLLSDGYHKPRSGNDAGDHPPITPMCSATEDMLGHD 1643
             Q LL+D Y KPR+G DAGDHPPITPM SA+ED LG+D
Sbjct: 300  AQKLLTDNYIKPRAGTDAGDHPPITPMRSASEDSLGND 337


>ref|XP_011000014.1| PREDICTED: DNA topoisomerase 3-beta isoform X1 [Populus euphratica]
          Length = 864

 Score =  762 bits (1967), Expect(2) = 0.0
 Identities = 354/461 (76%), Positives = 395/461 (85%), Gaps = 5/461 (1%)
 Frame = -1

Query: 1638 YICQHFLGTLSPECKYTRITVEFESGGESFHCVGQHVTVKGFTSIMPWLAVAEKNIPQFT 1459
            Y+CQHFLGT+SP+CKYTR  VEF  GGE FHC+G HV VKGFTSIMPWLAV+EKN+PQF 
Sbjct: 405  YVCQHFLGTVSPDCKYTRTKVEFSIGGEFFHCIGLHVIVKGFTSIMPWLAVSEKNLPQFA 464

Query: 1458 KGQKIDILRIEVEEGSTQPPDYLTESEAISLMEKNGIGTDASIPVHINNICERNYVQVQA 1279
            KG KI++ ++E+ EG T PPDYL+ESE ISLMEKNGIGTDASI VHINNICERNYVQVQA
Sbjct: 465  KGDKIEVSKVELFEGQTVPPDYLSESELISLMEKNGIGTDASISVHINNICERNYVQVQA 524

Query: 1278 GRRLVPTALGISLIRGYQCIDPDLCLPDIRSFIEHQIALVAKGQADHSLVVQHVIEQFKR 1099
            GR+LVPTALGI+LIRGYQCIDPDLCLPDIR FIE QI LVAKG+ADHS VVQHV+EQF+R
Sbjct: 525  GRKLVPTALGITLIRGYQCIDPDLCLPDIRGFIEQQITLVAKGEADHSCVVQHVLEQFRR 584

Query: 1098 KFIYFVKQIENMDALFEAEFSPLSDSGRVLSKCGKCLRYMKLISSQPSRLYCGTCEEIYY 919
            K+ YFVKQI+NMDALFEA+FSPL+DSGR  SKCGKCLRYMK ISSQPSRLYCGTCEE+YY
Sbjct: 585  KYSYFVKQIDNMDALFEAQFSPLADSGRAFSKCGKCLRYMKYISSQPSRLYCGTCEEVYY 644

Query: 918  TPPKGTIKLYKELICPLDNFELLIFSLPGPEGKSFPFCPYCYNSPPFEGIGNLYGASKTA 739
             P KGTIKLYKEL CPLDNFELLIF++ GPEGKSFP CP CYN+PPFEGI  L+GASKT 
Sbjct: 645  LPQKGTIKLYKELTCPLDNFELLIFAMAGPEGKSFPLCPLCYNNPPFEGIDALFGASKTG 704

Query: 738  GAVQLGKGAGMPCFLCPHPTCQHSMISQGVCACPECDGTLVLDPVSAPKWRLYCNMCNCL 559
             +  LGKGAGMPCFLCPHPTC+HS+I+QGVCACPEC+GTLVLDP SAPKWRLYCNMCNCL
Sbjct: 705  SSGMLGKGAGMPCFLCPHPTCRHSLIAQGVCACPECNGTLVLDPTSAPKWRLYCNMCNCL 764

Query: 558  VSLPEGAHRISTTKDHCPNCDSTILEVDFNKKTTPLKDGGTLHIGCILCDELLHSLVEMK 379
            V LP GAHRISTT++ CP CDSTI+EVDFN+ TTPL+DG TLH+GCILCD+LLHSLVE+K
Sbjct: 765  VLLPHGAHRISTTRERCPECDSTIIEVDFNRNTTPLEDGATLHVGCILCDDLLHSLVEVK 824

Query: 378  HGKSF-----RYXXXXXXXXXXXXXXXXRKQQDPKMSFRDF 271
            HGKSF     ++                 K  DPKMSFRDF
Sbjct: 825  HGKSFFKRAGKWARARGRGAYRGRGRGFGK-MDPKMSFRDF 864



 Score =  245 bits (626), Expect(2) = 0.0
 Identities = 119/158 (75%), Positives = 135/158 (85%)
 Frame = -3

Query: 2116 YIIHQGYELELQWERHRLFDSDVALMFQNLVKEDGMLKVIGMSEKQESKGRPAGLNTVKL 1937
            +++  GYEL+L+WERH+LFD DV LMFQ LV +D +L+V  MSEKQESKGRP GLNTV L
Sbjct: 241  HVMVDGYELQLEWERHKLFDLDVTLMFQKLVLQDRILEVTDMSEKQESKGRPPGLNTVNL 300

Query: 1936 LKVASSSLGFGPQLAMQLAERLYIQGFISYPRTESTAYPSSFDYKGTLGALARNSVFGDY 1757
            LK+ASS+LGFGPQ+ MQLAERLY QGFISYPRTESTAYPSSFD+KGTL ALA N ++GDY
Sbjct: 301  LKIASSALGFGPQVTMQLAERLYTQGFISYPRTESTAYPSSFDFKGTLSALANNPMWGDY 360

Query: 1756 VQLLLSDGYHKPRSGNDAGDHPPITPMCSATEDMLGHD 1643
            VQ LLS GYHKP+SG DAGDHPPITPM SA EDML  D
Sbjct: 361  VQGLLSGGYHKPQSGKDAGDHPPITPMRSANEDMLERD 398


>ref|XP_011000015.1| PREDICTED: DNA topoisomerase 3-beta isoform X2 [Populus euphratica]
          Length = 825

 Score =  762 bits (1967), Expect(2) = 0.0
 Identities = 354/461 (76%), Positives = 395/461 (85%), Gaps = 5/461 (1%)
 Frame = -1

Query: 1638 YICQHFLGTLSPECKYTRITVEFESGGESFHCVGQHVTVKGFTSIMPWLAVAEKNIPQFT 1459
            Y+CQHFLGT+SP+CKYTR  VEF  GGE FHC+G HV VKGFTSIMPWLAV+EKN+PQF 
Sbjct: 366  YVCQHFLGTVSPDCKYTRTKVEFSIGGEFFHCIGLHVIVKGFTSIMPWLAVSEKNLPQFA 425

Query: 1458 KGQKIDILRIEVEEGSTQPPDYLTESEAISLMEKNGIGTDASIPVHINNICERNYVQVQA 1279
            KG KI++ ++E+ EG T PPDYL+ESE ISLMEKNGIGTDASI VHINNICERNYVQVQA
Sbjct: 426  KGDKIEVSKVELFEGQTVPPDYLSESELISLMEKNGIGTDASISVHINNICERNYVQVQA 485

Query: 1278 GRRLVPTALGISLIRGYQCIDPDLCLPDIRSFIEHQIALVAKGQADHSLVVQHVIEQFKR 1099
            GR+LVPTALGI+LIRGYQCIDPDLCLPDIR FIE QI LVAKG+ADHS VVQHV+EQF+R
Sbjct: 486  GRKLVPTALGITLIRGYQCIDPDLCLPDIRGFIEQQITLVAKGEADHSCVVQHVLEQFRR 545

Query: 1098 KFIYFVKQIENMDALFEAEFSPLSDSGRVLSKCGKCLRYMKLISSQPSRLYCGTCEEIYY 919
            K+ YFVKQI+NMDALFEA+FSPL+DSGR  SKCGKCLRYMK ISSQPSRLYCGTCEE+YY
Sbjct: 546  KYSYFVKQIDNMDALFEAQFSPLADSGRAFSKCGKCLRYMKYISSQPSRLYCGTCEEVYY 605

Query: 918  TPPKGTIKLYKELICPLDNFELLIFSLPGPEGKSFPFCPYCYNSPPFEGIGNLYGASKTA 739
             P KGTIKLYKEL CPLDNFELLIF++ GPEGKSFP CP CYN+PPFEGI  L+GASKT 
Sbjct: 606  LPQKGTIKLYKELTCPLDNFELLIFAMAGPEGKSFPLCPLCYNNPPFEGIDALFGASKTG 665

Query: 738  GAVQLGKGAGMPCFLCPHPTCQHSMISQGVCACPECDGTLVLDPVSAPKWRLYCNMCNCL 559
             +  LGKGAGMPCFLCPHPTC+HS+I+QGVCACPEC+GTLVLDP SAPKWRLYCNMCNCL
Sbjct: 666  SSGMLGKGAGMPCFLCPHPTCRHSLIAQGVCACPECNGTLVLDPTSAPKWRLYCNMCNCL 725

Query: 558  VSLPEGAHRISTTKDHCPNCDSTILEVDFNKKTTPLKDGGTLHIGCILCDELLHSLVEMK 379
            V LP GAHRISTT++ CP CDSTI+EVDFN+ TTPL+DG TLH+GCILCD+LLHSLVE+K
Sbjct: 726  VLLPHGAHRISTTRERCPECDSTIIEVDFNRNTTPLEDGATLHVGCILCDDLLHSLVEVK 785

Query: 378  HGKSF-----RYXXXXXXXXXXXXXXXXRKQQDPKMSFRDF 271
            HGKSF     ++                 K  DPKMSFRDF
Sbjct: 786  HGKSFFKRAGKWARARGRGAYRGRGRGFGK-MDPKMSFRDF 825



 Score =  245 bits (626), Expect(2) = 0.0
 Identities = 119/158 (75%), Positives = 135/158 (85%)
 Frame = -3

Query: 2116 YIIHQGYELELQWERHRLFDSDVALMFQNLVKEDGMLKVIGMSEKQESKGRPAGLNTVKL 1937
            +++  GYEL+L+WERH+LFD DV LMFQ LV +D +L+V  MSEKQESKGRP GLNTV L
Sbjct: 202  HVMVDGYELQLEWERHKLFDLDVTLMFQKLVLQDRILEVTDMSEKQESKGRPPGLNTVNL 261

Query: 1936 LKVASSSLGFGPQLAMQLAERLYIQGFISYPRTESTAYPSSFDYKGTLGALARNSVFGDY 1757
            LK+ASS+LGFGPQ+ MQLAERLY QGFISYPRTESTAYPSSFD+KGTL ALA N ++GDY
Sbjct: 262  LKIASSALGFGPQVTMQLAERLYTQGFISYPRTESTAYPSSFDFKGTLSALANNPMWGDY 321

Query: 1756 VQLLLSDGYHKPRSGNDAGDHPPITPMCSATEDMLGHD 1643
            VQ LLS GYHKP+SG DAGDHPPITPM SA EDML  D
Sbjct: 322  VQGLLSGGYHKPQSGKDAGDHPPITPMRSANEDMLERD 359


>ref|XP_002516387.1| prokaryotic DNA topoisomerase, putative [Ricinus communis]
            gi|223544485|gb|EEF46004.1| prokaryotic DNA
            topoisomerase, putative [Ricinus communis]
          Length = 865

 Score =  762 bits (1967), Expect(2) = 0.0
 Identities = 353/461 (76%), Positives = 393/461 (85%), Gaps = 5/461 (1%)
 Frame = -1

Query: 1638 YICQHFLGTLSPECKYTRITVEFESGGESFHCVGQHVTVKGFTSIMPWLAVAEKNIPQFT 1459
            Y+CQHF+G++SP+CKY R  VEF  GGE FHC+GQHV V+GFTSIMPWLAV EKN+PQ  
Sbjct: 405  YVCQHFIGSVSPDCKYVRTKVEFSVGGEFFHCIGQHVIVEGFTSIMPWLAVTEKNLPQLV 464

Query: 1458 KGQKIDILRIEVEEGSTQPPDYLTESEAISLMEKNGIGTDASIPVHINNICERNYVQVQA 1279
            KG+KI++LR+E+ EG T PPDYLTESE ISLMEKNGIGTDASIPVHINNICERNYVQVQA
Sbjct: 465  KGEKIEVLRMELLEGKTTPPDYLTESELISLMEKNGIGTDASIPVHINNICERNYVQVQA 524

Query: 1278 GRRLVPTALGISLIRGYQCIDPDLCLPDIRSFIEHQIALVAKGQADHSLVVQHVIEQFKR 1099
            GRRL PT LGI+LIRGYQCIDPDLCLPDIRSFIE QI LVAKGQADHS VVQHV++QFK+
Sbjct: 525  GRRLAPTILGITLIRGYQCIDPDLCLPDIRSFIEQQITLVAKGQADHSRVVQHVLQQFKQ 584

Query: 1098 KFIYFVKQIENMDALFEAEFSPLSDSGRVLSKCGKCLRYMKLISSQPSRLYCGTCEEIYY 919
            KF YFVKQI+NMDALFEA+FS L DSGR LSKCGKCLRYMK IS+QP RLYCGTCEE+YY
Sbjct: 585  KFTYFVKQIDNMDALFEAQFSQLVDSGRALSKCGKCLRYMKYISTQPPRLYCGTCEEVYY 644

Query: 918  TPPKGTIKLYKELICPLDNFELLIFSLPGPEGKSFPFCPYCYNSPPFEGIGNLYGASKTA 739
             P KGTIKLYKEL CPLDNFELLIFS+ GPEGK+FP CPYCYN+PPFEG+  L+GASK  
Sbjct: 645  LPQKGTIKLYKELTCPLDNFELLIFSMAGPEGKTFPLCPYCYNNPPFEGVDTLFGASKNG 704

Query: 738  GAVQLGKGAGMPCFLCPHPTCQHSMISQGVCACPECDGTLVLDPVSAPKWRLYCNMCNCL 559
               +LGKGAGMPCFLCPHPTC+HS+I+QGVCACPEC GTLVLDPVSAPKWRLYCNMCNCL
Sbjct: 705  NFGKLGKGAGMPCFLCPHPTCRHSLIAQGVCACPECSGTLVLDPVSAPKWRLYCNMCNCL 764

Query: 558  VSLPEGAHRISTTKDHCPNCDSTILEVDFNKKTTPLKDGGTLHIGCILCDELLHSLVEMK 379
            V LP+GAHRI+TT++ CP CDSTI+EVDFNK TTPL+DG TLHIGCILCD+LLHSLVE+K
Sbjct: 765  VLLPQGAHRIATTRERCPECDSTIIEVDFNKNTTPLEDGATLHIGCILCDDLLHSLVEVK 824

Query: 378  HGKSF-----RYXXXXXXXXXXXXXXXXRKQQDPKMSFRDF 271
            HGKSF                        ++ DPKMSFRDF
Sbjct: 825  HGKSFFKRLGAGRRGRGAGRGRGRGRSSGRRGDPKMSFRDF 865



 Score =  239 bits (609), Expect(2) = 0.0
 Identities = 115/158 (72%), Positives = 135/158 (85%)
 Frame = -3

Query: 2116 YIIHQGYELELQWERHRLFDSDVALMFQNLVKEDGMLKVIGMSEKQESKGRPAGLNTVKL 1937
            ++I  GY+L+L+WERHRLFD DVALMFQ  V +DG+L+VI +S+KQE+KGRP+GLNTV L
Sbjct: 241  HLIIDGYQLQLEWERHRLFDLDVALMFQKQVLQDGILEVIDISQKQETKGRPSGLNTVNL 300

Query: 1936 LKVASSSLGFGPQLAMQLAERLYIQGFISYPRTESTAYPSSFDYKGTLGALARNSVFGDY 1757
            LKVASS+LGFGPQ+AMQLAERLY QGFISYPRTESTAYPSSFD+K  L  L  NS++GD 
Sbjct: 301  LKVASSALGFGPQMAMQLAERLYTQGFISYPRTESTAYPSSFDFKSILSTLLNNSIWGDS 360

Query: 1756 VQLLLSDGYHKPRSGNDAGDHPPITPMCSATEDMLGHD 1643
            V+ LL +GYHKPR G DAGDHPPITP+  ATEDMLG D
Sbjct: 361  VRRLLVEGYHKPRLGTDAGDHPPITPIRLATEDMLGKD 398