BLASTX nr result
ID: Papaver29_contig00031081
seq
BLASTX 2.2.25 [Feb-01-2011]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Papaver29_contig00031081
(2083 letters)
Database: ./nr
77,306,371 sequences; 28,104,191,420 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
ref|XP_001318162.1| viral A-type inclusion protein [Trichomonas ... 118 2e-23
ref|XP_653447.1| Viral A-type inclusion protein repeat [Entamoeb... 110 7e-21
ref|XP_009343332.1| PREDICTED: myosin-2 heavy chain-like isoform... 108 2e-20
ref|XP_009343331.1| PREDICTED: myosin-2 heavy chain, non muscle-... 108 2e-20
ref|XP_009343330.1| PREDICTED: myosin heavy chain, embryonic smo... 108 2e-20
ref|XP_009343342.1| PREDICTED: myosin-10-like [Pyrus x bretschne... 107 6e-20
ref|XP_804789.1| R27-2 protein [Trypanosoma cruzi strain CL Bren... 106 9e-20
ref|XP_808187.1| myosin heavy chain [Trypanosoma cruzi strain CL... 105 1e-19
ref|XP_001582797.1| viral A-type inclusion protein [Trichomonas ... 105 2e-19
ref|XP_009292628.1| PREDICTED: nesprin-1 isoform X4 [Danio rerio] 103 8e-19
ref|XP_009292627.1| PREDICTED: nesprin-1 isoform X3 [Danio rerio] 103 8e-19
gb|KFM76401.1| Myosin heavy chain, non-muscle, partial [Stegodyp... 103 8e-19
ref|XP_005159743.1| PREDICTED: nesprin-1 isoform X6 [Danio rerio] 103 8e-19
ref|XP_005159741.1| PREDICTED: nesprin-1 isoform X5 [Danio rerio] 103 8e-19
ref|XP_685984.6| PREDICTED: nesprin-1 isoform X1 [Danio rerio] 103 8e-19
ref|XP_012262786.1| PREDICTED: myosin-2 heavy chain-like isoform... 102 1e-18
ref|XP_012262776.1| PREDICTED: major antigen-like isoform X1 [At... 102 1e-18
ref|XP_001312904.1| viral A-type inclusion protein [Trichomonas ... 102 2e-18
ref|XP_001659192.1| AAEL001411-PA [Aedes aegypti] gi|108883254|g... 102 2e-18
ref|XP_001659191.1| AAEL001411-PB [Aedes aegypti] gi|108883253|g... 102 2e-18
>ref|XP_001318162.1| viral A-type inclusion protein [Trichomonas vaginalis G3]
gi|121900914|gb|EAY05939.1| viral A-type inclusion
protein, putative [Trichomonas vaginalis G3]
Length = 5296
Score = 118 bits (295), Expect = 2e-23
Identities = 125/516 (24%), Positives = 228/516 (44%), Gaps = 18/516 (3%)
Frame = -3
Query: 2072 ESKVSVFEAAIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDEL 1893
E K+ EA D+L ++ KK E K+ +E K+A EAAK D+L
Sbjct: 4266 EDKLKQAEAEKKATEDKLRETENAKKETEEKLAKTEEEKKQVEDKLAATEAAKKETEDKL 4325
Query: 1892 ERKKDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLE 1713
++ +D+ A K + + +++ ED + + E
Sbjct: 4326 KQTEDEKKATEDKLANVEAEKSDIEQAKKETEDKLKQTEEEKAAVEAEKKATEDKLHETE 4385
Query: 1712 VNILILHEELQKEKDDKTALIK-------DLVAAEPGKRTVNEIVSHLESKSRSLKEHFL 1554
++L++ +D+K A+ + L E K+ + E++ + L E F
Sbjct: 4386 EAKKETEDKLKQTEDEKAAVEQAKKETEDKLKQTEEEKKATENKLEESEAEKKELGERF- 4444
Query: 1553 REEEDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLE----KTVLE 1386
E E+ S+L + + ++EL+ K+ KS L + EAEK+ E KT +E
Sbjct: 4445 -ESSRGSTEKQVSDLENLLSKLKDELKNIKEDKSQLESKLKQAEAEKKATEDKLAKTEVE 4503
Query: 1385 RRASNLDTMDAIHEEELRKEKVDKSALTENGE-GCEAEKQGPEKTVLDLEPTIPSLNDAL 1209
+ A E+ +KE DK A EN + E +K K DL+ + L L
Sbjct: 4504 KAAL----------EQAKKETEDKLANVENEKKATETQKNDLAKEKTDLQKALAKL---L 4550
Query: 1208 QRDLDRVMAEKQALEKRCSDLEAKNASLTD---NQEGHEAEIERKLEAS--NLTHNDELH 1044
+R +++ AEK+ALE++ + LE++ + + N E + E + KL+ + NL ++
Sbjct: 4551 KRQ-EQLDAEKKALEEKANALESEKKATEEKLANAEKEKKETQDKLKQTEDNLAKSESEK 4609
Query: 1043 KEKDDK-KSIMNDLDRVKAEKQVLESKVSDLETTYSTLNNELQQKMDDNEAFLNERDGLE 867
K +DK K ++ +++A K+ E K+ + E +L+Q + +A + E
Sbjct: 4610 KATEDKLKQTESEKAQIEAAKKETEDKLQNAENEKKAAEEKLKQSEEQKKATEEKLQEAE 4669
Query: 866 AVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLL 687
A K+ ++++ ++EA + + K E LK+ + +L EA ++ K
Sbjct: 4670 AEKKAEQEKLANIEAEKQQLGNASEKQVSDLSGEISKLKQLLKQLAEAKKKADEELAKSK 4729
Query: 686 KDINIWLSEVTELQEDLNKESKEKQDLEKRVLELTS 579
+D ++ ++LQEDLN K+ +DLEK E S
Sbjct: 4730 QDKEQSDNDKSKLQEDLNNLKKQLEDLEKAKKESDS 4765
Score = 97.1 bits (240), Expect = 6e-17
Identities = 118/519 (22%), Positives = 221/519 (42%), Gaps = 14/519 (2%)
Frame = -3
Query: 2081 QALESKVSVFEAAIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLN 1902
Q +E K +V + + D N+K + +++ L+ L+ K+ DLE
Sbjct: 4089 QIVEEKSAVERQLVESQKDSSENQKQQDE----EKSKLQQQLSDLQNKLNDLEKKLADKE 4144
Query: 1901 DELERKKDDNNAIIKKA--LDKRISDLKADAPQ-RDQEDDMNALIXXXXXXXXXXXXXXK 1731
+E E++K + + K+ L K +L+ + + +D+ D M I
Sbjct: 4145 NEKEQEKTQKDDLQKQLDQLQKDFDNLEREKQKLQDKNDSMKETIDSKNMLLDSFGTIKD 4204
Query: 1730 IVSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLR 1551
+++ N L +E K +DD + +N +++L+++ ++ +E L+
Sbjct: 4205 HLNDANNNNKKLQDENNKLRDDAQKATSKNNELQSIIDDLNRKLANLDAEKKATEEK-LK 4263
Query: 1550 EEEDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASN 1371
ED++ + A K E++LR+ ++ K E E EK+ +E + A+
Sbjct: 4264 NTEDKLKQAEAE-----KKATEDKLRETENAKKETEEKLAKTEEEKKQVEDKLAATEAAK 4318
Query: 1370 LDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDR 1191
+T E++L++ + +K A + EAEK E+ + E + + +
Sbjct: 4319 KET-----EDKLKQTEDEKKATEDKLANVEAEKSDIEQAKKETEDKLKQTEE----EKAA 4369
Query: 1190 VMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASNLTHNDELHKEKDDKKSIMN 1011
V AEK+A E + + E D + E E + +E + D+L + +++KK+ N
Sbjct: 4370 VEAEKKATEDKLHETEEAKKETEDKLKQTEDE-KAAVEQAKKETEDKLKQTEEEKKATEN 4428
Query: 1010 DLDRVKAEKQVL-----------ESKVSDLETTYSTLNNELQQKMDDNEAFLNERDGLEA 864
L+ +AEK+ L E +VSDLE S L +EL+ +D
Sbjct: 4429 KLEESEAEKKELGERFESSRGSTEKQVSDLENLLSKLKDELKNIKED------------- 4475
Query: 863 VKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLLK 684
K LE ++ EA E K K E EK L++ E E+ ++ + ++ K
Sbjct: 4476 -KSQLESKLKQAEAEKKATEDKLAK----TEVEKAALEQAKKETEDKLANVENEKK---- 4526
Query: 683 DINIWLSEVTELQEDLNKESKEKQDLEKRVLELTSKLEK 567
TE Q+ N +KEK DL+K + +L + E+
Sbjct: 4527 --------ATETQK--NDLAKEKTDLQKALAKLLKRQEQ 4555
Score = 95.5 bits (236), Expect = 2e-16
Identities = 121/543 (22%), Positives = 237/543 (43%), Gaps = 40/543 (7%)
Frame = -3
Query: 2075 LESKVSVFEAAIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDE 1896
L +++ + ++ L D+L +++++ + + N+R L K ++E + D +A L +
Sbjct: 3074 LTDQLNQVKNQLSALQDQLKSKENENEKLRNEREKLANEKNSVELQSKDKDAEIIKLKSD 3133
Query: 1895 LERKKDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNL 1716
E D N++ + + ++ K + + +N L + + N+
Sbjct: 3134 AEHLNDKINSLNDEKNKLQQANDKLNDQIEQMKQQINNLTNENKNMEQEKAKNQEKIQNI 3193
Query: 1715 EVNILILHEELQKEKDDKTA------LIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFL 1554
E + L EE K +D+ + +KD + K +E + L +S S
Sbjct: 3194 EPKLKQLEEEKSKLEDENSQNENEIQRLKDTIKELSDKLAKSEEDNKLLKQSSSGTTDKQ 3253
Query: 1553 REEEDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEG----CEAEKQGLEKTVLE 1386
E+ E+L + +L + + E+L+++KD S + N E + + L K LE
Sbjct: 3254 VEDLQEMLNKLRDDLKNLNS-ENEQLKQQKDQLSEKLNNSNNDKTKAETQNEQLSKQ-LE 3311
Query: 1385 RRASNLDTM-----DAIHEE---ELRKEKV---------DKSALTENGEGCEAEKQGPEK 1257
+ + + M +AI ++ E+ KE + +K +L + + EK E+
Sbjct: 3312 QLNNEKNQMFNKYKNAIQDKAKVEIAKETLAKDNEKLASEKESLQQKLDSANDEKNKLEQ 3371
Query: 1256 TVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQ---EGHEAEIER 1086
LE LNDA + EK L ++ +DL K L + + E +A+ E+
Sbjct: 3372 DKHKLEIDNTKLNDAKSH----LENEKSQLAQQINDLNNKLQKLEEEKNKLEEEKAQNEK 3427
Query: 1085 KLEASNLTHNDELHKEKDDKKSIMNDLDRVKAEKQVLESKVSDLETTYSTLNN---ELQQ 915
KLE S D+L ++ D ++ L+ +K + Q E + S LE + + N E++Q
Sbjct: 3428 KLENSQ-QDGDKLGQQNQD---LLKQLEEIKQKLQQTEQEKSALEQQKNEIQNKLNEIEQ 3483
Query: 914 KMDDNEA----FLNERDGLEAVKQGLEKRVLDLEATIHDIEMK---TGKDDDYNEAEKQT 756
+M D+E + +E K +K++ + E ++I+ K T ++ E EK
Sbjct: 3484 QMKDSEKEKEDIKQKLQQVEQEKSETQKKLEEAEQQKNEIQNKLEQTEQEKKNLENEKAE 3543
Query: 755 LKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLELTSK 576
+KR+ E EEA L ++ + + + +E E + LN+ + ++LE E K
Sbjct: 3544 TEKRLQETEEAKKNLANEKSEAERKLEEVQNEKAETERKLNEAEEANKNLENEKNETQKK 3603
Query: 575 LEK 567
LE+
Sbjct: 3604 LEE 3606
Score = 86.7 bits (213), Expect = 8e-14
Identities = 103/519 (19%), Positives = 215/519 (41%), Gaps = 15/519 (2%)
Frame = -3
Query: 2078 ALESKVSVFEAAIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLND 1899
ALE + + + + + ++ + + +K+ I +E K + K+ + E K + +
Sbjct: 3466 ALEQQKNEIQNKLNEIEQQMKDSEKEKEDIKQKLQQVEQEKSETQKKLEEAEQQKNEIQN 3525
Query: 1898 ELERKKDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSN 1719
+LE+ + + K + + KA+ +R QE + + N
Sbjct: 3526 KLEQTEQEK---------KNLENEKAETEKRLQETE-------------------EAKKN 3557
Query: 1718 LEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEED 1539
L +L++ +++K + L AE + + + + K ++ + E
Sbjct: 3558 LANEKSEAERKLEEVQNEKAETERKLNEAEEANKNLENEKNETQKKLEEAEQQ--KAETQ 3615
Query: 1538 EVLERSAS---NLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGL--EKTVLERRAS 1374
++LE++ NLA K+ E +L++ ++ K L E + + + EK ER+ +
Sbjct: 3616 KLLEQTEEAKKNLANEKSEAERKLQETEEAKKNLANEKSEAERKLEEVQNEKAETERKLN 3675
Query: 1373 NLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLD 1194
+ + + L EK + E E +AE Q + + + + + +R L
Sbjct: 3676 EAEEAN----KNLENEKNETQKKLEEAEQQKAETQKLLEQTEEAKKNLANEKSEAERKLQ 3731
Query: 1193 RVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASNLTHNDELHKEKDDKKSIM 1014
K+ L S+ E K + + +AE ERKL + N L EK++ + +
Sbjct: 3732 ETEEAKKNLANEKSEAERK----LEEVQNEKAETERKLNEAEEA-NKNLENEKNETQKKL 3786
Query: 1013 NDLDRVKAEKQVLESKVSDLETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRV- 837
+ ++ KAE Q L + + + +E ++K+ + E + LE K ++K++
Sbjct: 3787 EEAEQQKAETQKLLEQTEEAKKNLENEKSETEKKLQETE---EAKKNLEQEKSDIQKKLD 3843
Query: 836 ------LDLE---ATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLLK 684
++LE A + +T + E EK +KR+ E EEA L ++ + +
Sbjct: 3844 ETKQQKVNLENEKAETQKLLEETEEAKKNLENEKAETEKRLQETEEAKKNLANEKSEAER 3903
Query: 683 DINIWLSEVTELQEDLNKESKEKQDLEKRVLELTSKLEK 567
+ +E E + LN+ + ++LE E KLE+
Sbjct: 3904 KLEEVQNEKAETERKLNEAEEANKNLENEKNETQKKLEE 3942
Score = 80.9 bits (198), Expect = 4e-12
Identities = 113/530 (21%), Positives = 216/530 (40%), Gaps = 28/530 (5%)
Frame = -3
Query: 2072 ESKVSVFEAAIATLNDELLNEKDDKKCIVNDRN--------------ILEAAKQALEYKV 1935
E+K+ I + D++ N+K+ K + N +LE K+ E
Sbjct: 2863 ETKLQNANQQIEMMKDQINNDKEQIKSAQDKLNDLQNKNNELNSNQIVLENQKKMYEGLY 2922
Query: 1934 ADLEAAKTTLNDELERKKDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXX 1755
D++++ LNDE +K D + K+ + +S LK + + + E
Sbjct: 2923 NDMKSSNDKLNDENRKKTDQIIDLTKQ--NAEVSALKLENQRLNSE-------------- 2966
Query: 1754 XXXXXXXKIVSNLEV--NILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESK 1581
K+ SN V N L +++++ K L + E K + + LES+
Sbjct: 2967 -----LEKLKSNQPVSSNDPELQKQIEELKKQLNNLSNEKKQIETEKNGLQGQIGRLESQ 3021
Query: 1580 SRSLKE--HFLREEEDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQG 1407
+ SL E ++E+ D++ + +E+R+E ++L +N E G
Sbjct: 3022 NESLIESKKDMKEQNDKL------------QAQMDEMRRE---NNSLRQNQTQLERTNNG 3066
Query: 1406 LEKTVLERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIP 1227
LE V NL ++L + K SAL + + E E
Sbjct: 3067 LENKV-----GNL-------TDQLNQVKNQLSALQDQLKSKENE---------------- 3098
Query: 1226 SLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEI------ERKLEASNL 1065
N+ L+ + +++ EK ++E + D +A+ L + E +I + KL+ +N
Sbjct: 3099 --NEKLRNEREKLANEKNSVELQSKDKDAEIIKLKSDAEHLNDKINSLNDEKNKLQQAND 3156
Query: 1064 THNDELHKEKDDKKSIMNDLDRVKAEKQVLESKVSDLETTYSTLNNELQQKMDDNEAFLN 885
ND++ + K ++ N+ ++ EK + K+ ++E L E + D+N N
Sbjct: 3157 KLNDQIEQMKQQINNLTNENKNMEQEKAKNQEKIQNIEPKLKQLEEEKSKLEDENSQNEN 3216
Query: 884 ERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQ----TLKKRISELEEAIS 717
E + L+ TI ++ K K ++ N+ KQ T K++ +L+E ++
Sbjct: 3217 E--------------IQRLKDTIKELSDKLAKSEEDNKLLKQSSSGTTDKQVEDLQEMLN 3262
Query: 716 ILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLELTSKLEK 567
L D K L + + +L E LN + +K E + +L+ +LE+
Sbjct: 3263 KLRDDLKNLNSENEQLKQQKDQLSEKLNNSNNDKTKAETQNEQLSKQLEQ 3312
Score = 79.7 bits (195), Expect = 9e-12
Identities = 104/490 (21%), Positives = 218/490 (44%), Gaps = 30/490 (6%)
Frame = -3
Query: 1946 EYKVADLEAAKTTLNDELERKKDDNNAIIKKALDKRISDL----KADAPQRDQEDDMNAL 1779
E + +D+E +T + + E + +++ +K L ++S+L K + + D+ +N
Sbjct: 2347 EKEASDVEVVCSTRDVDFEYENENDPETLKSLLKSKLSELENLQKENKAKEDEITKLNEE 2406
Query: 1778 IXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDKTALIKDLVA--AEPGKRTVNE 1605
+ N E+N L H+ELQ E++ + LI+DL + EP K +
Sbjct: 2407 LAKSEDAKRRELAETAERLNNEINTL--HDELQNEQNARQKLIEDLQSNNKEPEKDDNGD 2464
Query: 1604 IVSHLESKSRSLKEHFLREEEDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGC 1425
++ LE KS + + +E+L R + KA+R+ E K K L
Sbjct: 2465 FMNVLEKKSDEINKAL-----EEILHRQNEEI---KALRDREAEKNKQTVDDL------- 2509
Query: 1424 EAEKQGLEKTVLERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLD 1245
+KQ + + + S+ D + +E + +E +S N +A + + +
Sbjct: 2510 --QKQ-IAMLNNKLKPSDQTDNDQLQKELMFQEIEGESPEDRNKRYLKAIEDKFNEIIAK 2566
Query: 1244 LEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASNL 1065
L+ +I + N+ L++ L + A+E + + +A+ + DN E +AE E+++E +N
Sbjct: 2567 LQESINNQNEELKK-LRQKCDGVDAIELQLAQKKAELNEIKDNYEKEKAEREKEVEENNK 2625
Query: 1064 THND-------ELHKEKDDKKSIMN-----------DLDRVKAEKQVLESKVSDLETTYS 939
D L + + +S +N D D ++ L++++++L+ Y+
Sbjct: 2626 KLKDTINALENRLDSQGEQTRSKINSAEQTARKAKEDADSAVIAQKSLQAELNNLKQKYA 2685
Query: 938 TLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNE---A 768
L ++L+ + + N + + +K+ E+ + IH + K K + NE
Sbjct: 2686 VLEDQLKTEKE------NHQQEAQQLKELAEEDATPM-VCIHVVGEKLKKLQNDNEKLSE 2738
Query: 767 EKQTLKKRISELEEAISILTDKAKK---LLKDINIWLSEVTELQEDLNKESKEKQDLEKR 597
L+K I+EL++ I+ L + K+ L +++ L + E +L E+K ++ +
Sbjct: 2739 NNDNLQKNINELKDKINGLEKQYKQDAAELSNVHHQLGALQEKATNLENENKSLKEENED 2798
Query: 596 VLELTSKLEK 567
++ +LEK
Sbjct: 2799 LMNQNKQLEK 2808
Score = 75.9 bits (185), Expect = 1e-10
Identities = 104/519 (20%), Positives = 217/519 (41%), Gaps = 31/519 (5%)
Frame = -3
Query: 2036 TLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADL---EAAKTTLNDELERKKDDNNA 1866
T N +L N D+ K ++++ L+ ++ DL +A + LN+ K+D A
Sbjct: 535 TKNSDLQNSNDEYKKLIDE----------LQNQLKDLAKNKAESSDLNNSENTKQDSEKA 584
Query: 1865 IIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEE 1686
+ A K +L+ ++ + E++ + +LE N+ +++
Sbjct: 585 EDENAETKSNKELQEESDKLKSENE-------------------GLKKSLE-NLKKSNDD 624
Query: 1685 LQKEKDDKTALIKDLVAA-EPGKRTVNEI----------VSHLESKSRSLKEHFLREEED 1539
L K +DK IK+L + K +NE+ + L SK S++ L ++ED
Sbjct: 625 LNKSNEDKENKIKELESEISKLKSEINELEQNNKDKDREIEILSSKVSSIENVNLDDDED 684
Query: 1538 EVLERSASNLAIMKAI---REEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNL 1368
++ ++++ + I E E + E + + EN E N+
Sbjct: 685 DITVVGTRDISVDETIPTDNETETKTEPETNTNTNENTN--------------ETNEENV 730
Query: 1367 DTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRV 1188
+ + +EE+ + ++ K + + A KQG + + S N+ L + +
Sbjct: 731 SSQEGNNEEKNQSKEDKKKLRIQQLKQLLASKQGEVDALKSQNDDLKSENETLSKSNHEL 790
Query: 1187 MAEKQALEKRCSDLEA-KNASLTDNQEGHEAEIERKLEASNLTHNDELHKE--KDDKKSI 1017
+ + LE+ ++ K + D +E + E+ + + +E E K KS
Sbjct: 791 ETKNKELEEEIENINNNKEGEVIDEKEASDVEVVCSTRDVDFEYENENDPETLKSLLKSK 850
Query: 1016 MNDLDRVKAEKQVLESKVSDLETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQG----- 852
+++L+ ++ E L ++ +L+ L EL+ +NE+ E + L+
Sbjct: 851 LSELENLQKENTDLMKQIEELKNENENLKRELENLKLENESLKRENERLQLTADQSPQSK 910
Query: 851 ------LEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKL 690
L ++ LE+ + +++ KT NE E+ LKK +++E +K KK
Sbjct: 911 DKMIELLANQINQLESLVPELQQKT------NEIEE--LKKENKQIKEE----NEKLKKE 958
Query: 689 LKDINIWLSEVTELQEDLNKESKEKQDLEKRVLELTSKL 573
+D+ S + E++N +E++DL+K++ +L L
Sbjct: 959 NEDLK--KSGSNKSSEEIN---QEEEDLKKQIEDLKKAL 992
Score = 72.0 bits (175), Expect = 2e-09
Identities = 92/524 (17%), Positives = 209/524 (39%), Gaps = 40/524 (7%)
Frame = -3
Query: 2024 ELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKALD 1845
+L ++ KK + N+++ E + ++ + A+ E + + +++ N KK +
Sbjct: 3638 KLQETEEAKKNLANEKSEAERKLEEVQNEKAETERKLNEAEEANKNLENEKNETQKKLEE 3697
Query: 1844 KRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDD 1665
+ E+ L + NL +L++ +++
Sbjct: 3698 AEQQKAETQKLLEQTEEAKKNLANEKSEAERKLQETEEAKKNLANEKSEAERKLEEVQNE 3757
Query: 1664 KTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSAS---NLAIMKA 1494
K + L AE + + + + K ++ + E ++LE++ NL K+
Sbjct: 3758 KAETERKLNEAEEANKNLENEKNETQKKLEEAEQQ--KAETQKLLEQTEEAKKNLENEKS 3815
Query: 1493 IREEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHEEELRKEKVDK 1314
E++L++ ++ K L E EK ++K + E + ++ + E + E+ ++
Sbjct: 3816 ETEKKLQETEEAKKNL-------EQEKSDIQKKLDETKQQKVNLENEKAETQKLLEETEE 3868
Query: 1313 SALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKN 1134
+ E E EK+ E + + + + +R L+ V EK E++ ++ E N
Sbjct: 3869 AKKNLENEKAETEKRLQETE--EAKKNLANEKSEAERKLEEVQNEKAETERKLNEAEEAN 3926
Query: 1133 ASLTD-------------------------------NQEGHEAEIERKLEAS-----NLT 1062
+L + N E ++E E+KL+ + NL
Sbjct: 3927 KNLENEKNETQKKLEEAEQQKAETQKLLEQTEEAKKNLENEKSETEKKLQETEEAKKNLE 3986
Query: 1061 HN-DELHKEKDDKKSIMNDLDRVKAEKQVLESKVSDLETTYSTLNNELQQKMDDNEAFLN 885
++ K+ D+ K +L+ KAE Q L + + + E Q+K+D+
Sbjct: 3987 QEKSDIQKKLDETKQQKVNLENEKAETQKLLEETEEAKKNLENEKAETQKKLDE------ 4040
Query: 884 ERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTD 705
E K+ LE+ D E + +++ + E EK +K++ E E+A + +
Sbjct: 4041 ----AEEAKKNLEQEKSDAEKKLEEVQ----NEKSALENEKNETQKKLEEAEKAKDQIVE 4092
Query: 704 KAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLELTSKL 573
+ + + + + + E+ ++ +EK L++++ +L +KL
Sbjct: 4093 EKSAVERQL---VESQKDSSENQKQQDEEKSKLQQQLSDLQNKL 4133
Score = 70.1 bits (170), Expect = 7e-09
Identities = 143/586 (24%), Positives = 242/586 (41%), Gaps = 99/586 (16%)
Frame = -3
Query: 2027 DELLNEKDD-KKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKA 1851
+EL NE ++ KK I + +L + E+K E K N+EL+++ D+ +K+A
Sbjct: 1536 EELKNENNELKKQIEALKRVLGYPEDGNEHKTPS-ELIKE--NEELKKQNDN----LKRA 1588
Query: 1850 LD--------KRISDLKADAPQRDQE-DDMNALIXXXXXXXXXXXXXXKIVSNLEVNILI 1698
L K S+L A+ + +E DD+ + I N
Sbjct: 1589 LGYPEDGKDHKSPSELIAEIEELKKENDDLKRALGYPEDDKDHKSPSELIKEN------- 1641
Query: 1697 LHEELQKEKDD--KTALIKDLVAAEPGKRTVNEIVSHLESKSRSL------KEHFLREE- 1545
EEL+KE DD K I +AE + E+ +E ++L KEH E
Sbjct: 1642 --EELKKENDDLKKRLGISGESSAEESN-SPEELKKQIEDLKKALGYPEDGKEHKTPSEL 1698
Query: 1544 --EDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASN 1371
E+E L++ N A+ +A+ E K+ S L++ E + + + LEK +
Sbjct: 1699 IKENEELKKQ--NDALKRALGYPEDGKDHKSPSELIQENEELKKKVEDLEKAL----GYP 1752
Query: 1370 LDTMDAIHEEELRKEKVD-KSALTENGEGCEAEKQGPEKTVLD---LEPTIPSLNDAL-- 1209
D D EL KE + K L + E + + PE+ + L+ I L AL
Sbjct: 1753 QDGKDHKSPSELLKENEELKKKLGISDESSTEDNKSPEELKNENKYLKKQIEGLKKALGY 1812
Query: 1208 ------QRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASNLT-HNDE 1050
+ ++ E + L+K+ SDLE D +E H++ E E L N
Sbjct: 1813 PEDGKEHKSPSELIQENEDLKKKVSDLEKALGYPEDGKE-HKSPSELLKENEELKKENQR 1871
Query: 1049 LHKEKDDKKS------------IMNDL------------DRVKAEKQVLESKVSDLETTY 942
L KE + K IMN+ + +K E + L+ ++ DL+ +
Sbjct: 1872 LKKENAELKKRLGIPVDQIIEGIMNESTASDESEDNKSPEELKREIENLKKQLEDLKNSG 1931
Query: 941 STLN------------------------------NELQQKMDDN----EAFLNERDGLEA 864
S N ++LQQK+DD E + + +E
Sbjct: 1932 SQENVDEENNEMKEGADNLIDALQQSVDEKNKQIDDLQQKLDDQNREIELLKAKVEQIEN 1991
Query: 863 VKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLLK 684
+ + + + + +T D+E++ +++ EA K+ L ++IS+L++ LT+K K L+
Sbjct: 1992 INEEEDNEDIVVAST-RDVELENVEEESPEEA-KERLAEQISQLQDK---LTEKKKNSLQ 2046
Query: 683 DINIWLS---EVTELQEDLNKESKEKQD----LEKRVLELTSKLEK 567
S E+++L E++ + EK+D LEK ELT LEK
Sbjct: 2047 MKQALASKDAEISKLNEEIEQIKSEKEDQDKELEKLNNELTEALEK 2092
Score = 68.9 bits (167), Expect = 2e-08
Identities = 120/563 (21%), Positives = 240/563 (42%), Gaps = 74/563 (13%)
Frame = -3
Query: 2042 IATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAI 1863
I TL+DEL NE++ ++ ++ D L++ + E + + LE+K D+ N
Sbjct: 2429 INTLHDELQNEQNARQKLIED---LQSNNKEPE------KDDNGDFMNVLEKKSDEINKA 2479
Query: 1862 IKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEEL 1683
+++ L ++ ++KA RD+E + N + V +L+ I +L+ +L
Sbjct: 2480 LEEILHRQNEEIKA---LRDREAEKNK----------------QTVDDLQKQIAMLNNKL 2520
Query: 1682 Q-KEKDDKTALIKDLVAAE-----PGKRT----------VNEIVSHLESKSRSLKEHF-- 1557
+ ++ D L K+L+ E P R NEI++ L+ + E
Sbjct: 2521 KPSDQTDNDQLQKELMFQEIEGESPEDRNKRYLKAIEDKFNEIIAKLQESINNQNEELKK 2580
Query: 1556 LREEEDEV-------------LERSASNLAIMKAIREEEL----RKEKDGKSALVEN--- 1437
LR++ D V L N KA RE+E+ +K KD +AL
Sbjct: 2581 LRQKCDGVDAIELQLAQKKAELNEIKDNYEKEKAEREKEVEENNKKLKDTINALENRLDS 2640
Query: 1436 -GEGCEAEKQGLEKTV----------------LERRASNLDTMDAIHEEELRKEKVDKSA 1308
GE ++ E+T L+ +NL A+ E++L+ EK +
Sbjct: 2641 QGEQTRSKINSAEQTARKAKEDADSAVIAQKSLQAELNNLKQKYAVLEDQLKTEKENHQQ 2700
Query: 1307 LTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNAS 1128
+ + E P + + + L Q D +++ L+K ++L+ K
Sbjct: 2701 EAQQLKELAEEDATPMVCIHVVGEKLKKL----QNDNEKLSENNDNLQKNINELKDKING 2756
Query: 1127 LTDNQEGHEAEIER--------KLEASNLTHNDELHKEKDDKKSIMNDLDRVKAEKQVLE 972
L + AE+ + +A+NL + ++ KE+++ +MN +++ EKQ L
Sbjct: 2757 LEKQYKQDAAELSNVHHQLGALQEKATNLENENKSLKEENE--DLMNQNKQLEKEKQQLL 2814
Query: 971 SKVSDLETTYSTLNNELQQKMDDNEAFLNERDG----LEAVKQGLEKRVLDLEATIHDIE 804
++ S+LE + L + N+ L + D LE +K+ + L+ IE
Sbjct: 2815 AQNSNLEENKNNQEQSLMNRKKKNDDLLKQIDDLKLELEELKRNNSQNETKLQNANQQIE 2874
Query: 803 MKTGKDDDYNEAEK-QTLKKRISELE------EAISILTDKAKKLLKDINIWLSEVTELQ 645
M KD N+ E+ ++ + ++++L+ + I+ + KK+ + + +++
Sbjct: 2875 MM--KDQINNDKEQIKSAQDKLNDLQNKNNELNSNQIVLENQKKMYEGL---YNDMKSSN 2929
Query: 644 EDLNKESKEKQDLEKRVLELTSK 576
+ LN E+++K D ++++LT +
Sbjct: 2930 DKLNDENRKKTD---QIIDLTKQ 2949
Score = 67.0 bits (162), Expect = 6e-08
Identities = 113/568 (19%), Positives = 235/568 (41%), Gaps = 66/568 (11%)
Frame = -3
Query: 2078 ALESKVSVFEAAIATLNDELLNEKDDKKC-------------------IVNDRNI----- 1971
++ S +S+++ + +LNDEL K + + + N+ N+
Sbjct: 150 SISSTISIYDENLESLNDELSRLKQNSQNSELVKVLDNLTRTTDYVVNLENNENLERYTT 209
Query: 1970 LEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAI------IKKALDK---RISDLKAD 1818
+A +A+ L +LN EL+ K + + K+ + K I ++
Sbjct: 210 YDAQLRAISQAALRLSTKVNSLNAELQELKHSQSEMQIIVSQYKEVVPKISFHIETIEKL 269
Query: 1817 APQRD-QEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDKTALIKDL 1641
D EDD N LI +N + N +ELQK K+ + L +++
Sbjct: 270 VSINDTDEDDKNPLIFPQRLKRIRSEVQRLFDNNEKTN-----KELQKLKE-QLELYENM 323
Query: 1640 VAAEPGKRTVNEIVS---HLESKSRSLKEHFLREE---------EDEVLERSASNLAIMK 1497
+ K E+ S LE K+ L++ R + E E +E NL
Sbjct: 324 KNGQSMKERQAELESLRLELEKKNAELEQLKARYQSKQDPQLLAEIERIENEVQNLKNKI 383
Query: 1496 AIREEELRK----------EKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDA-- 1353
A RE +++ + + K ++EN E E + L+K + E + ++ + A
Sbjct: 384 ADRESQIKALNLLIAQYQTDDEDKKEIIEN---LEKEIKDLKKQI-EDKDKEIEVLKAKI 439
Query: 1352 IHEEELRKEKVDKSALTENGEGCE-AEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEK 1176
EE+ +++ D+ + + + E + LE + L + L + K
Sbjct: 440 AKIEEIPEDEEDEDIVVAGTRDVDLGDFNEEEAEQVSLEDQVKQLKEKLDDKKKNGVQMK 499
Query: 1175 QALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASNLTHNDELHKEKDDKKSIMNDLDRV 996
QAL + +++E N + + ++ ++ + E+ +E N T N +L D+ K ++++L
Sbjct: 500 QALASKDAEIEKLNEQIQELKDRNDKQ-EQNIEELN-TKNSDLQNSNDEYKKLIDELQNQ 557
Query: 995 KAEKQVLESKVSDLETTYSTLNNELQQKMDD-------NEAFLNERDGLEAVKQGLEKRV 837
+ +++ SDL + +T + +K +D N+ E D L++ +GL+K +
Sbjct: 558 LKDLAKNKAESSDLNNSENTKQDS--EKAEDENAETKSNKELQEESDKLKSENEGLKKSL 615
Query: 836 LDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEV 657
+L+ + +DD N++ + + +I ELE SE+
Sbjct: 616 ENLKKS----------NDDLNKSNEDK-ENKIKELE---------------------SEI 643
Query: 656 TELQEDLNKESKEKQDLEKRVLELTSKL 573
++L+ ++N+ + +D ++ + L+SK+
Sbjct: 644 SKLKSEINELEQNNKDKDREIEILSSKV 671
Score = 63.2 bits (152), Expect = 9e-07
Identities = 125/557 (22%), Positives = 223/557 (40%), Gaps = 71/557 (12%)
Frame = -3
Query: 2030 NDELLNEKDDKKCI-VNDRNILEAAKQ----ALEYKVADLEAAKTTL---NDELERKKDD 1875
N+E K+DKK + + L A+KQ AL+ + DL++ TL N ELE K +
Sbjct: 737 NEEKNQSKEDKKKLRIQQLKQLLASKQGEVDALKSQNDDLKSENETLSKSNHELETKNKE 796
Query: 1874 ---------NNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVS 1722
NN + +K SD++ RD + + + +
Sbjct: 797 LEEEIENINNNKEGEVIDEKEASDVEVVCSTRDVDFEYE------------NENDPETLK 844
Query: 1721 NLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEE 1542
+L + L E LQKE D L+K + + + + +L+ ++ SLK E
Sbjct: 845 SLLKSKLSELENLQKENTD---LMKQIEELKNENENLKRELENLKLENESLKR------E 895
Query: 1541 DEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDT 1362
+E L+ +A K E L + + +LV + E + L+K + + N
Sbjct: 896 NERLQLTADQSPQSKDKMIELLANQINQLESLVPELQQKTNEIEELKKENKQIKEEN--- 952
Query: 1361 MDAIHEEELRKEKVD--KSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDL-DR 1191
E+L+KE D KS ++ E E++ +K + DL+ + D +
Sbjct: 953 ------EKLKKENEDLKKSGSNKSSEEINQEEEDLKKQIEDLKKALGYPQDGKEHKTPSE 1006
Query: 1190 VMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASNLTHNDELHKEKDDKKSIMN 1011
++ E + L+K+ DLE ++ +DN+ E K + L N+EL K+ DD + +
Sbjct: 1007 LIEENEELKKKVEDLEKESGYPSDNK-------EHKSPSELLKENEELKKKVDDLEKALG 1059
Query: 1010 DLDRVKAEKQVLESKVSDLETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQG--LEKRV 837
+ K K S++ N+ L++ + E + + E +++ L+K+V
Sbjct: 1060 YPEDGKDHKS--PSELIKENEELKKQNDALKRALGYPEDGKDHKSPSELIQENEELKKKV 1117
Query: 836 LDLEATI-------------------HDIEMKTG-------KDDDYNE------AEKQTL 753
DLE + +++ K G D++ N+ +E + L
Sbjct: 1118 ADLEKALGYPADGQEHKTPSELLRENEELKKKLGISDSTTPSDNEDNKSPEELRSENKDL 1177
Query: 752 KKRISELEEAISILTD-----------KAKKLLKDINIWLSEVTELQEDLNKES------ 624
KK+I +L+ A+ D K + LK N L + ED
Sbjct: 1178 KKQIEDLKRALGYPEDGKEHKTPSELIKENEELKKQNDSLKKALGYSEDGKDHKSPSELI 1237
Query: 623 KEKQDLEKRVLELTSKL 573
KE +DL+K+V +L L
Sbjct: 1238 KENEDLKKKVEDLEKAL 1254
Score = 62.0 bits (149), Expect = 2e-06
Identities = 77/361 (21%), Positives = 156/361 (43%), Gaps = 2/361 (0%)
Frame = -3
Query: 1649 KDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNLAIMKAIREEELRK 1470
+D + E KR + + LE S + + EE +E+ E A NL + L++
Sbjct: 1905 EDNKSPEELKREIENLKKQLEDLKNSGSQENVDEENNEMKE-GADNLI-------DALQQ 1956
Query: 1469 EKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHEEELRKEKVDKSALTENGE 1290
D K+ +++ + +K + +E + ++ ++ I+EEE ++ V S T + E
Sbjct: 1957 SVDEKNKQIDDLQ----QKLDDQNREIELLKAKVEQIENINEEEDNEDIVVAS--TRDVE 2010
Query: 1289 GCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQE 1110
E++ PE+ L I L D L + KQAL +
Sbjct: 2011 LENVEEESPEEAKERLAEQISQLQDKLTEKKKNSLQMKQALASK---------------- 2054
Query: 1109 GHEAEIERKLEASNLTHNDELHKEKDDKKSIMNDLDRVKAE-KQVLESKVSDLETTYSTL 933
+AEI + N+E+ + K +K+ +L+++ E + LE + + +
Sbjct: 2055 --DAEISKL--------NEEIEQIKSEKEDQDKELEKLNNELTEALEKLENGKKKSSQEQ 2104
Query: 932 NNELQQK-MDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQT 756
NNE ++ +DD E ER+ L++ + L+ + + E +E +DD N++ +
Sbjct: 2105 NNENEEDFVDDIEKLKEERENLKSENESLKNQAPENEGLKKSLENLKKSNDDLNKSNEDK 2164
Query: 755 LKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLELTSK 576
+ +I ELE SE+++L+ ++N+ + +D ++ + L+SK
Sbjct: 2165 -ENKIKELE---------------------SEISKLKSEINELEQNNKDKDREIEILSSK 2202
Query: 575 L 573
+
Sbjct: 2203 V 2203
Score = 60.8 bits (146), Expect = 5e-06
Identities = 106/542 (19%), Positives = 220/542 (40%), Gaps = 40/542 (7%)
Frame = -3
Query: 2075 LESKVSVFEAAIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAA------- 1917
L+ KVS E A+ D E ++ + L+ Q L+ + A+L+
Sbjct: 1832 LKKKVSDLEKALGYPEDG--KEHKSPSELLKENEELKKENQRLKKENAELKKRLGIPVDQ 1889
Query: 1916 -------KTTLNDELERKKDDNNAIIKKALD---KRISDLKADAPQRDQEDDMNALIXXX 1767
++T +DE E K +K+ ++ K++ DLK Q + +++ N +
Sbjct: 1890 IIEGIMNESTASDESEDNKSPEE--LKREIENLKKQLEDLKNSGSQENVDEENNEM---- 1943
Query: 1766 XXXXXXXXXXXKIVSNLEVNILILH---EELQKEKDDKTALIKDLVAAEPGKRTVNEIVS 1596
++ L+ ++ + ++LQ++ DD+ I+ L A +NE
Sbjct: 1944 ------KEGADNLIDALQQSVDEKNKQIDDLQQKLDDQNREIELLKAKVEQIENINEEED 1997
Query: 1595 HLESKSRSLKEHFLREEEDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAE 1416
+ + S ++ L E+E E + LA + +++L ++K + + +AE
Sbjct: 1998 NEDIVVASTRDVELENVEEESPEEAKERLAEQISQLQDKLTEKKKNSLQMKQALASKDAE 2057
Query: 1415 KQGLEKTVLERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKT---VLD 1245
L + + + ++ D + E+L E + ENG+ +++Q E V D
Sbjct: 2058 ISKLNEEIEQIKSEKEDQDKEL--EKLNNELTEALEKLENGKKKSSQEQNNENEEDFVDD 2115
Query: 1244 LE------PTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERK 1083
+E + S N++L+ E + L+K +L+ N L + E E +I+
Sbjct: 2116 IEKLKEERENLKSENESLKNQ----APENEGLKKSLENLKKSNDDLNKSNEDKENKIK-- 2169
Query: 1082 LEASNLTHNDELHKEKDDKKSIMNDLDRVKAEK----QVLESKVSDLETTY-------ST 936
EL E KS +N+L++ +K ++L SKVS +E T
Sbjct: 2170 ----------ELESEISKLKSEINELEQNNKDKDREIEILSSKVSSIENVNLDDDEDDIT 2219
Query: 935 LNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQT 756
+ +D+ NE + + E ++ + G +++ N++++
Sbjct: 2220 VVGTRDISVDETIPTDNETETKTEPETNTNTNENTNETNEENVSSQEGNNEEKNQSKEDK 2279
Query: 755 LKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLELTSK 576
K RI +L++ +L K +++ S+ +L+ + SK +L + EL +
Sbjct: 2280 KKLRIQQLKQ---LLASKQ----GEVDALKSQNDDLKSENETLSKSNHELGTKTKELEEE 2332
Query: 575 LE 570
+E
Sbjct: 2333 IE 2334
>ref|XP_653447.1| Viral A-type inclusion protein repeat [Entamoeba histolytica
HM-1:IMSS] gi|56470397|gb|EAL48061.1| Viral A-type
inclusion protein repeat, putative [Entamoeba histolytica
HM-1:IMSS]
Length = 1813
Score = 110 bits (274), Expect = 7e-21
Identities = 126/583 (21%), Positives = 258/583 (44%), Gaps = 67/583 (11%)
Frame = -3
Query: 2072 ESKVSVFEAAIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDEL 1893
+ KV + E L D++ NE D + + ++ K+++ ++ + K ++N+EL
Sbjct: 218 KKKVEILENEKKDLIDKMANENDGMSKLNEELTQIKNEKESINNELIQTKQEKESINNEL 277
Query: 1892 ERKKDDN----NAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIV 1725
+ K DN N + + +K K + + + E MN L ++
Sbjct: 278 TQLKTDNDQKENELNQVRHEKDEVIEKFNTSKEENEKIMNEL--------------SQLK 323
Query: 1724 SNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHF--LR 1551
E L E+++K +++K+ LI +L G +NE ++ + + + ++
Sbjct: 324 QEKEEKENELKEQVKKMEEEKSKLITELSNGSDGISKLNEELTQTKQEKEEINNELNSIK 383
Query: 1550 EEEDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASN 1371
EE+ + E + K I+EE+ + E++ K L E E EK+G L+ +
Sbjct: 384 EEKKRIEEEKNQIINENKEIKEEKEKIEEEKKELLKE----IEKEKEG--NNQLQNEINT 437
Query: 1370 LDT-MDAIHE----------EELRKEKVDKSALTENGEGCEAEKQGPE---KTVLDLEPT 1233
+ T M I E +E+ K K ++ L + + EKQ E ++D++
Sbjct: 438 IQTRMKEIEEKNQEIICDNNKEIAKFKEEQENLQKELNQIKEEKQKTENEKNELVDVKTQ 497
Query: 1232 IPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASNLTHND 1053
+ + L+ + +++ EK +E + + + LT+ +E + E++ ++A N T
Sbjct: 498 KENELNKLKEEKEQIFNEKTTIENSLNQIVEEKNKLTEEKESIKQELD-SIKADNSTKEL 556
Query: 1052 ELHKEKDDKKSIMNDLDRVKAEKQVLESKVSDLETTYSTLNNEL------QQKMDDNEAF 891
E++K ++K + ND D V+ EK+ ++ +++ ++ S EL +Q+++D +A
Sbjct: 557 EINKINEEKNQLQNDYDTVQQEKENIQKELNQIKIEKSQKEEELNKIKEEKQQVEDEKAK 616
Query: 890 L-----NERDGLEAVKQGLEKRVLDLEATIHDI-EMKTGKDDDYNEAEKQTLKKRISELE 729
L N DGL + + ++K + E +++ ++K +D+ NE K K+ I + E
Sbjct: 617 LITDIANGNDGLTKLNEVIDKLKDEKENISNELNQIKNERDNISNEFNK--TKEEIKQKE 674
Query: 728 EAISILTDKAKKLLKDINIWL------------------SEVTELQED-------LNKES 624
L ++ LL ++N +E+T+L ED LN+
Sbjct: 675 NETIQLNEEKSVLLNELNQIKEEKQKIEDEKAVIQQEKENEITKLNEDKTVIENELNQIK 734
Query: 623 KEKQDLE----------KRVLELTSKLEKCICGARDGLSTIKE 525
EKQ++E +++ + SKL + DG+S + E
Sbjct: 735 TEKQEIENELNQTKDEKQKIEDEKSKLITELSNGNDGISKLNE 777
Score = 102 bits (255), Expect = 1e-18
Identities = 110/517 (21%), Positives = 234/517 (45%), Gaps = 14/517 (2%)
Frame = -3
Query: 2033 LNDELLNEKDDKKCIVNDRNI---LEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAI 1863
L+ +N ++ KK ++ +N + K +E + + T+N+ELE+ K + N +
Sbjct: 1124 LSQSNINLEEVKKDLIESQNKYTQINEEKDCVEQERNKINEEYKTVNEELEKNKKELNDL 1183
Query: 1862 IKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEEL 1683
K D I +L + +D++N+LI +NL+ L E++
Sbjct: 1184 QTK-YDNEILELNKN------KDELNSLI-----------------NNLKEEKTNLEEQV 1219
Query: 1682 QKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHF--LREEEDEVLERSASNL 1509
+K +++K+ LI +L G +NE ++ + + + ++EE+ + E +
Sbjct: 1220 KKMEEEKSKLITELSNGSDGVSKLNEELTQTKQEKEEINNELNSIKEEKKRIEEEKNQII 1279
Query: 1508 AIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDT----MDAIHEE 1341
K I+EE+ + E++ K L E E EK+G + L+ + + T ++ ++E
Sbjct: 1280 NENKEIKEEKEKIEEEKKELLKE----IEKEKEGNNQ--LQNEINTIQTRMKEIEEKNQE 1333
Query: 1340 ELRKEKVDKSALTENGEGCEAE----KQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQ 1173
+ + + E E + E K+ K + DL L+ L +++ + EK+
Sbjct: 1334 IICDNNKEIAKFKEEQENLQKELNQIKEEKSKLITDLSNGNDGLSK-LNEEIETINKEKE 1392
Query: 1172 ALEKRCSDLEAKNASLTDNQEGHEAEIER-KLEASNLTHNDELHKEKDDKKSIMNDLDRV 996
+ K L+ +N + D E E+ + K E L H +L D + DL+++
Sbjct: 1393 GIRKELESLKEENNKIQDELEQKNQELSKVKEEKEKLIH--DLTNGNDGINQLNEDLNQI 1450
Query: 995 KAEKQVLESKVSDLETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATI 816
K +K+ L K L+ + L +E +++ +N +F E++GL+ V + + + + +
Sbjct: 1451 KNDKEELTEKNVQLQNEINKLKSE-NEELSNNLSF--EKEGLKQVNEEVNAIKEERDELV 1507
Query: 815 HDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDL 636
I+ K ++ ++ L SE+ E I+ + ++ ++L ++ N + ELQ +
Sbjct: 1508 KQIK----KIEEEKRKVEEELNFNGSEVNEQIAQINNEKEQLNQECNELKQNLKELQSKI 1563
Query: 635 NKESKEKQDLEKRVLELTSKLEKCICGARDGLSTIKE 525
+ +EK+ E + E +L++ I + + +KE
Sbjct: 1564 EEIEQEKESNEIKKKEELQELQEEITEKDNDIKNLKE 1600
Score = 99.4 bits (246), Expect = 1e-17
Identities = 111/542 (20%), Positives = 240/542 (44%), Gaps = 65/542 (11%)
Frame = -3
Query: 2036 TLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIK 1857
++N+EL+ K +K+ I N+ L+ E ++ + K + ++ K++N I+
Sbjct: 258 SINNELIQTKQEKESINNELTQLKTDNDQKENELNQVRHEKDEVIEKFNTSKEENEKIMN 317
Query: 1856 KALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQK 1677
+ +S LK +++E+ N L +SN I L+EEL +
Sbjct: 318 E-----LSQLK-----QEKEEKENELKEQVKKMEEEKSKLITELSNGSDGISKLNEELTQ 367
Query: 1676 EKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHF--LREEEDEVL-----ERSA 1518
K +K + +L + + K+ + E + + ++++ +KE + EE+ E+L E+
Sbjct: 368 TKQEKEEINNELNSIKEEKKRIEEEKNQIINENKEIKEEKEKIEEEKKELLKEIEKEKEG 427
Query: 1517 SNL---------AIMKAIREE----------ELRKEKDGKSALVENGEGCEAEKQGLEKT 1395
+N MK I E+ E+ K K+ + L + + EKQ E
Sbjct: 428 NNQLQNEINTIQTRMKEIEEKNQEIICDNNKEIAKFKEEQENLQKELNQIKEEKQKTENE 487
Query: 1394 ---VLERRASNLDTMDAIHEE--ELRKEKV-----------DKSALTENGEGCEAEKQGP 1263
+++ + + ++ + EE ++ EK +K+ LTE E + E
Sbjct: 488 KNELVDVKTQKENELNKLKEEKEQIFNEKTTIENSLNQIVEEKNKLTEEKESIKQELDSI 547
Query: 1262 EKTVLDLEPTIPSLNDA---LQRDLDRVMAEKQALEKRCSDLEAKNASLTDN-----QEG 1107
+ E I +N+ LQ D D V EK+ ++K + ++ + + + +E
Sbjct: 548 KADNSTKELEINKINEEKNQLQNDYDTVQQEKENIQKELNQIKIEKSQKEEELNKIKEEK 607
Query: 1106 HEAEIERKLEASNLTH--------NDELHKEKDDKKSIMNDLDRVKAEKQVLESKVSDLE 951
+ E E+ +++ + N+ + K KD+K++I N+L+++K E+ + ++ + +
Sbjct: 608 QQVEDEKAKLITDIANGNDGLTKLNEVIDKLKDEKENISNELNQIKNERDNISNEFNKTK 667
Query: 950 TTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGL--EKRVLDLEATIHDIEMKTGKDDDY 777
NE Q ++ LNE + ++ KQ + EK V+ E ++ K
Sbjct: 668 EEIKQKENETIQLNEEKSVLLNELNQIKEEKQKIEDEKAVIQQEKENEITKLNEDKTVIE 727
Query: 776 NE-----AEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQ 612
NE EKQ ++ +++ ++ + D+ KL+ +++ +++L E+L + +EK+
Sbjct: 728 NELNQIKTEKQEIENELNQTKDEKQKIEDEKSKLITELSNGNDGISKLNEELTQTKQEKE 787
Query: 611 DL 606
++
Sbjct: 788 NV 789
Score = 99.0 bits (245), Expect = 1e-17
Identities = 119/581 (20%), Positives = 254/581 (43%), Gaps = 77/581 (13%)
Frame = -3
Query: 2033 LNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIK- 1857
+N+EL + K++KK I ++N + + ++ + +E K L E+E++K+ NN +
Sbjct: 375 INNELNSIKEEKKRIEEEKNQIINENKEIKEEKEKIEEEKKELLKEIEKEKEGNNQLQNE 434
Query: 1856 --------KALDKRISDLKAD---------APQRDQEDDMNALIXXXXXXXXXXXXXXKI 1728
K ++++ ++ D Q + + ++N + +
Sbjct: 435 INTIQTRMKEIEEKNQEIICDNNKEIAKFKEEQENLQKELNQIKEEKQKTENEKNELVDV 494
Query: 1727 VSNLEVNILILHEELQKEKDDKTALIKDL--VAAEPGKRTVN------------------ 1608
+ E + L EE ++ ++KT + L + E K T
Sbjct: 495 KTQKENELNKLKEEKEQIFNEKTTIENSLNQIVEEKNKLTEEKESIKQELDSIKADNSTK 554
Query: 1607 --EIVSHLESKSRSLKEHFLREEEDEVLERSASNLAIMKAIREEELRKEK---------- 1464
EI E K++ ++ ++E E +++ + + I K+ +EEEL K K
Sbjct: 555 ELEINKINEEKNQLQNDYDTVQQEKENIQKELNQIKIEKSQKEEELNKIKEEKQQVEDEK 614
Query: 1463 -----------DGKSALVENGEGCEAEKQGL--EKTVLERRASNLDTMDAIHEEELRKEK 1323
DG + L E + + EK+ + E ++ N+ +EE+++++
Sbjct: 615 AKLITDIANGNDGLTKLNEVIDKLKDEKENISNELNQIKNERDNISNEFNKTKEEIKQKE 674
Query: 1322 -------VDKSALTENGEGCEAEKQ--GPEKTVL--DLEPTIPSLND---ALQRDLDRVM 1185
+KS L + EKQ EK V+ + E I LN+ ++ +L+++
Sbjct: 675 NETIQLNEEKSVLLNELNQIKEEKQKIEDEKAVIQQEKENEITKLNEDKTVIENELNQIK 734
Query: 1184 AEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASNLTHNDELHKEKDDKKSIMNDL 1005
EKQ +E + + + + D + E+ + + N+EL + K +K++++N+L
Sbjct: 735 TEKQEIENELNQTKDEKQKIEDEKSKLITELSNGNDGISKL-NEELTQTKQEKENVLNEL 793
Query: 1004 DRVKAEKQVLESKVSDLETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLE 825
+++K E + + + E NN++QQ+++ NE LE K + +L
Sbjct: 794 NQIKNEFASFKEQNTQKENELKDENNKVQQELEQKN---NEVSKLEEEKGNISN---ELS 847
Query: 824 ATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQ 645
T ++E K K + +++ K+ +EL+E + + ++ KL+ +++ +++L
Sbjct: 848 NTKQELEQK--KQEIITITQEKEEKE--NELKEQVKKIEEEKSKLITELSNGSDGISKLN 903
Query: 644 EDLNKESKEKQDLEKRVLELTSKLEKCICGARDGLSTIKEA 522
E+L + +EK++++K + E KLE+ L IKEA
Sbjct: 904 EELTQTKQEKEEIQKALEEEKEKLER----IETELKEIKEA 940
Score = 92.8 bits (229), Expect = 1e-15
Identities = 107/517 (20%), Positives = 236/517 (45%), Gaps = 29/517 (5%)
Frame = -3
Query: 2033 LNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKK 1854
+N+EL + K++KK I ++N + + ++ + +E K L E+E++K+ NN + +
Sbjct: 1257 INNELNSIKEEKKRIEEEKNQIINENKEIKEEKEKIEEEKKELLKEIEKEKEGNNQLQNE 1316
Query: 1853 ALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKE 1674
I + +++QE K ++ + L +EL +
Sbjct: 1317 I--NTIQTRMKEIEEKNQE---------------IICDNNKEIAKFKEEQENLQKELNQI 1359
Query: 1673 KDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHF--LREEEDEV---LERSASNL 1509
K++K+ LI DL G +NE + + + +++ L+EE +++ LE+ L
Sbjct: 1360 KEEKSKLITDLSNGNDGLSKLNEEIETINKEKEGIRKELESLKEENNKIQDELEQKNQEL 1419
Query: 1508 AIMKAIREE---ELRKEKDGKSALVENGEGCEAEKQGL-EKTV--------LERRASNLD 1365
+ +K +E+ +L DG + L E+ + +K+ L EK V L+ L
Sbjct: 1420 SKVKEEKEKLIHDLTNGNDGINQLNEDLNQIKNDKEELTEKNVQLQNEINKLKSENEELS 1479
Query: 1364 TMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVM 1185
+ +E L++ + +A+ E + + + E+ +E + + + ++
Sbjct: 1480 NNLSFEKEGLKQVNEEVNAIKEERDELVKQIKKIEEEKRKVEEELNFNGSEVNEQIAQIN 1539
Query: 1184 AEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASNLTHNDELHKEKDDKKSIMNDL 1005
EK+ L + C++L+ L E EIE++ E++ + +EL + +++ ND+
Sbjct: 1540 NEKEQLNQECNELKQNLKELQSKIE----EIEQEKESNEIKKKEELQELQEEITEKDNDI 1595
Query: 1004 DRVKAEKQVLESKVSDLETTYSTLNN------ELQQKMDDNEAFL-NERDGLEAVKQGLE 846
+K E + +E ++ + E ++N EL+ K+ + + L E+ E++ E
Sbjct: 1596 KNLKEEIERIEKELQEKEEDMEQMSNNTEELEELKNKLTETQRLLEEEKKEKESISNEFE 1655
Query: 845 KR----VLDLEATIHDI-EMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLLKD 681
+ +++L+ +++ +M K +D NE E EL+E I +K K ++
Sbjct: 1656 ETKEQVLVELQRVNNEMNKMNEIKQEDENEKE---------ELQEHI----NKLKSQIER 1702
Query: 680 INIWLSEVTELQEDLNKESKEKQDLEKRVLELTSKLE 570
N L EV++L+ +L++ E + +++ ++ S L+
Sbjct: 1703 ENEQLKEVSKLKWELSELKTENESMKQMIMNKKSLLD 1739
Score = 89.7 bits (221), Expect = 9e-15
Identities = 111/547 (20%), Positives = 246/547 (44%), Gaps = 57/547 (10%)
Frame = -3
Query: 2036 TLNDELLNEKDDKKCIVN--DRNILEAAKQALEYK--VADLEAAKTTLNDELERKKDDNN 1869
T+N+EL K + + D ILE K E + +L+ KT L +++++ +++ +
Sbjct: 1168 TVNEELEKNKKELNDLQTKYDNEILELNKNKDELNSLINNLKEEKTNLEEQVKKMEEEKS 1227
Query: 1868 AIIKKALDKR--ISDLKADAPQRDQEDDM--NALIXXXXXXXXXXXXXXKIVS-NLEVNI 1704
+I + + +S L + Q QE + N L +I++ N E+
Sbjct: 1228 KLITELSNGSDGVSKLNEELTQTKQEKEEINNELNSIKEEKKRIEEEKNQIINENKEIK- 1286
Query: 1703 LILHEELQKEKDDKTALIKDLVAAEPGKRTV-NEI------VSHLESKSRSL-----KEH 1560
EE +K +++K L+K++ + G + NEI + +E K++ + KE
Sbjct: 1287 ----EEKEKIEEEKKELLKEIEKEKEGNNQLQNEINTIQTRMKEIEEKNQEIICDNNKEI 1342
Query: 1559 FLREEEDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERR 1380
+EE E L++ + + K+ +L DG S L E E EK+G+ K + +
Sbjct: 1343 AKFKEEQENLQKELNQIKEEKSKLITDLSNGNDGLSKLNEEIETINKEKEGIRKELESLK 1402
Query: 1379 ASNLDTMDAIHE--EELRKEKVDKSAL----TENGEGCEAEKQGPEKTVLDLEPTIPSLN 1218
N D + + +EL K K +K L T +G + + D E + N
Sbjct: 1403 EENNKIQDELEQKNQELSKVKEEKEKLIHDLTNGNDGINQLNEDLNQIKNDKEE-LTEKN 1461
Query: 1217 DALQRDLDRVMAEKQALEKRCS----DLEAKNASLTDNQEGHEA-------------EIE 1089
LQ +++++ +E + L S L+ N + +E + ++E
Sbjct: 1462 VQLQNEINKLKSENEELSNNLSFEKEGLKQVNEEVNAIKEERDELVKQIKKIEEEKRKVE 1521
Query: 1088 RKLEASNLTHNDELHKEKDDKKSIMNDLDRVKAEKQVLESKVSDLETTYSTLNNELQQKM 909
+L + N+++ + ++K+ + + + +K + L+SK+ ++E + + ++++
Sbjct: 1522 EELNFNGSEVNEQIAQINNEKEQLNQECNELKQNLKELQSKIEEIEQEKESNEIKKKEEL 1581
Query: 908 DDNEAFLNERDG-LEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNE-----AEKQTLKK 747
+ + + E+D ++ +K+ +E+ +L+ D+E + ++ E E Q L +
Sbjct: 1582 QELQEEITEKDNDIKNLKEEIERIEKELQEKEEDMEQMSNNTEELEELKNKLTETQRLLE 1641
Query: 746 RISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESK-------EKQDLEKRVLE 588
+ +E+IS ++ K+ + L E+ + ++NK ++ EK++L++ + +
Sbjct: 1642 EEKKEKESISNEFEETKEQV------LVELQRVNNEMNKMNEIKQEDENEKEELQEHINK 1695
Query: 587 LTSKLEK 567
L S++E+
Sbjct: 1696 LKSQIER 1702
Score = 80.9 bits (198), Expect = 4e-12
Identities = 108/569 (18%), Positives = 225/569 (39%), Gaps = 84/569 (14%)
Frame = -3
Query: 2027 DELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKAL 1848
+EL K++K+ I N++ +E + + + L K ++ EL+ K DN+
Sbjct: 500 NELNKLKEEKEQIFNEKTTIENSLNQIVEEKNKLTEEKESIKQELDSIKADNST------ 553
Query: 1847 DKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKD 1668
K + K + + ++D + + S E + + EE Q+ +D
Sbjct: 554 -KELEINKINEEKNQLQNDYDTVQQEKENIQKELNQIKIEKSQKEEELNKIKEEKQQVED 612
Query: 1667 DKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHF--------------------LRE 1548
+K LI D+ G +NE++ L+ + ++ +++
Sbjct: 613 EKAKLITDIANGNDGLTKLNEVIDKLKDEKENISNELNQIKNERDNISNEFNKTKEEIKQ 672
Query: 1547 EEDEVLERSASNLAIMKAIRE--EELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRAS 1374
+E+E ++ + ++ + + EE +K +D K+ + + E E K +KTV+E +
Sbjct: 673 KENETIQLNEEKSVLLNELNQIKEEKQKIEDEKAVIQQEKEN-EITKLNEDKTVIENELN 731
Query: 1373 NLDTMDAIHEEELRKEKVDKSALTE----------NG--------EGCEAEKQGPEKTVL 1248
+ T E EL + K +K + + NG E KQ E +
Sbjct: 732 QIKTEKQEIENELNQTKDEKQKIEDEKSKLITELSNGNDGISKLNEELTQTKQEKENVLN 791
Query: 1247 DL-----------------EPTIPSLNDALQRDLDRVMAEKQALEKRCSDL--------- 1146
+L E + N+ +Q++L++ E LE+ ++
Sbjct: 792 ELNQIKNEFASFKEQNTQKENELKDENNKVQQELEQKNNEVSKLEEEKGNISNELSNTKQ 851
Query: 1145 ---EAKNASLTDNQEGHEAEIE-----RKLEASNLTHNDELHKEKDDKKSIMNDLDRVKA 990
+ K +T QE E E E +K+E EL D + +L + K
Sbjct: 852 ELEQKKQEIITITQEKEEKENELKEQVKKIEEEKSKLITELSNGSDGISKLNEELTQTKQ 911
Query: 989 EKQVLESKVSDLETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHD 810
EK+ ++ + + + + EL++ + + E++ K L++ + + + + +
Sbjct: 912 EKEEIQKALEEEKEKLERIETELKEIKEAKQELEEEKNKTIEEKTNLQQELNENKKIVEE 971
Query: 809 I-EMKTGKDDDYNEAEK-QTLKKRISE-----LEEAISILTDKAKKL---LKDINIWLSE 660
+ + K K++ NE + KKRI E + E I + K + ++IN +
Sbjct: 972 LTQTKQEKEEINNELNSIKEEKKRIEEEKNQIINENKEIKEENIKSIEEKTQEINSLTTS 1031
Query: 659 VTELQEDLNKESKEKQDLEKRVLELTSKL 573
+ EL+ L + E+ ++EK + S+L
Sbjct: 1032 IEELKGRLEESKGERIEIEKERDRVISEL 1060
Score = 79.7 bits (195), Expect = 9e-12
Identities = 112/543 (20%), Positives = 236/543 (43%), Gaps = 37/543 (6%)
Frame = -3
Query: 2042 IATLNDELLNEKDDKKCIVNDRNILEAAKQALEY---KVADLEAAKTTLNDELERKKDDN 1872
I+ LN+EL K +K+ I + LE K+ LE ++ +++ AK L +E + ++
Sbjct: 899 ISKLNEELTQTKQEKEEI---QKALEEEKEKLERIETELKEIKEAKQELEEEKNKTIEEK 955
Query: 1871 NAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVS-NLEVNILIL 1695
+ ++ + + + ++++E+ N L +I++ N E+
Sbjct: 956 TNLQQELNENKKIVEELTQTKQEKEEINNELNSIKEEKKRIEEEKNQIINENKEIK---- 1011
Query: 1694 HEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVLER--- 1524
EE K ++KT I L + + E+ LE E + +E D V+
Sbjct: 1012 -EENIKSIEEKTQEINSLTTS------IEELKGRLEESKGERIE--IEKERDRVISELND 1062
Query: 1523 -SASNLAIMKAIREE-----ELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDT 1362
N + K + E E++K +G + N + + ++ + + L T
Sbjct: 1063 IKLQNEGMKKQVEEAHNRMTEMQKSFEGSENEMINSLNNQITQLNEKEKQMNEQVMALQT 1122
Query: 1361 M---DAIHEEELRKEKVDK----SALTENGEGCEAEKQGPE---KTVLD-LEPTIPSLND 1215
I+ EE++K+ ++ + + E + E E+ KTV + LE LND
Sbjct: 1123 QLSQSNINLEEVKKDLIESQNKYTQINEEKDCVEQERNKINEEYKTVNEELEKNKKELND 1182
Query: 1214 ALQRDLDRVMAE----KQALEKRCSDLEAKNASLTDNQEGHEAEIERKL-EASNLTH--- 1059
LQ D + E K L ++L+ + +L + + E E + + E SN +
Sbjct: 1183 -LQTKYDNEILELNKNKDELNSLINNLKEEKTNLEEQVKKMEEEKSKLITELSNGSDGVS 1241
Query: 1058 --NDELHKEKDDKKSIMNDLDRVKAEKQVLESKVSDLETTYSTLNNELQQKMDDNEAFLN 885
N+EL + K +K+ I N+L+ +K EK+ +E + + + + E ++ ++ + L
Sbjct: 1242 KLNEELTQTKQEKEEINNELNSIKEEKKRIEEEKNQIINENKEIKEEKEKIEEEKKELLK 1301
Query: 884 ERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTD 705
E + + L+ + ++ + +IE K + N E K+ L++ ++ + +
Sbjct: 1302 EIEKEKEGNNQLQNEINTIQTRMKEIEEKNQEIICDNNKEIAKFKEEQENLQKELNQIKE 1361
Query: 704 KAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLEL---TSKLEKCICGARDGLST 534
+ KL+ D++ +++L E++ +KEK+ + K + L +K++ + LS
Sbjct: 1362 EKSKLITDLSNGNDGLSKLNEEIETINKEKEGIRKELESLKEENNKIQDELEQKNQELSK 1421
Query: 533 IKE 525
+KE
Sbjct: 1422 VKE 1424
Score = 72.0 bits (175), Expect = 2e-09
Identities = 76/381 (19%), Positives = 162/381 (42%), Gaps = 36/381 (9%)
Frame = -3
Query: 1622 KRTVNEIVSHLESK---SRSLKEHFLREEEDEVLERSASNLAIMKAIREEELRKEKDGKS 1452
KR E H S+ + SL EE + + EEL+K+ D +
Sbjct: 145 KRNSTENTGHSSSEHSATSSLASETTAEEVNRSVNAQIEEENKRLQNENEELKKKCDAQD 204
Query: 1451 ALVENGEGCEAEK-------QGLEKTVLERRASNLDTMDAIHEEELRKEKVDKSALTENG 1293
+L++ E E + +K ++++ A+ D M ++EE L + K +K ++
Sbjct: 205 SLLKTKMKSEMEAKKKVEILENEKKDLIDKMANENDGMSKLNEE-LTQIKNEKESINNEL 263
Query: 1292 EGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDN- 1116
+ EK+ + L+ ND + +L++V EK + ++ + + +N + +
Sbjct: 264 IQTKQEKESINNELTQLKTD----NDQKENELNQVRHEKDEVIEKFNTSKEENEKIMNEL 319
Query: 1115 ----QEGHEAEIERKLEASNLTH-------------------NDELHKEKDDKKSIMNDL 1005
QE E E E K + + N+EL + K +K+ I N+L
Sbjct: 320 SQLKQEKEEKENELKEQVKKMEEEKSKLITELSNGSDGISKLNEELTQTKQEKEEINNEL 379
Query: 1004 DRVKAEKQVLESKVSDLETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLE 825
+ +K EK+ +E + + + + E ++ ++ + L E + + L+ + ++
Sbjct: 380 NSIKEEKKRIEEEKNQIINENKEIKEEKEKIEEEKKELLKEIEKEKEGNNQLQNEINTIQ 439
Query: 824 ATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQ 645
+ +IE K + N E K+ L++ ++ + ++ +K + N + T+ +
Sbjct: 440 TRMKEIEEKNQEIICDNNKEIAKFKEEQENLQKELNQIKEEKQKTENEKNELVDVKTQKE 499
Query: 644 EDLNKESKEKQDL--EKRVLE 588
+LNK +EK+ + EK +E
Sbjct: 500 NELNKLKEEKEQIFNEKTTIE 520
Score = 60.5 bits (145), Expect = 6e-06
Identities = 65/307 (21%), Positives = 129/307 (42%), Gaps = 15/307 (4%)
Frame = -3
Query: 1469 EKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHEEELRKEKVDKSALTENGE 1290
EK G A E + + EK ++R S L ++ K TEN
Sbjct: 105 EKSGDEAKNEQKQSSSQTSESTEKETHKKRLSFLG-----------RKSFSKRNSTENTG 153
Query: 1289 GCEAEKQGPEKTVLDL--EPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDN 1116
+E + E S+N ++ + R+ E + L+K+C + SL
Sbjct: 154 HSSSEHSATSSLASETTAEEVNRSVNAQIEEENKRLQNENEELKKKCDAQD----SLLKT 209
Query: 1115 QEGHEAEIERKLEASNLTHNDELHK---EKDDKKSIMNDLDRVKAEKQVLESKVSDLETT 945
+ E E ++K+E D + K E D + +L ++K EK+
Sbjct: 210 KMKSEMEAKKKVEILENEKKDLIDKMANENDGMSKLNEELTQIKNEKE------------ 257
Query: 944 YSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIE-----MKTGKDDD 780
++NNEL Q + E+ NE L +K +++ +L H+ + T K+++
Sbjct: 258 --SINNELIQTKQEKESINNE---LTQLKTDNDQKENELNQVRHEKDEVIEKFNTSKEEN 312
Query: 779 ---YNEAE--KQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEK 615
NE KQ +++ +EL+E + + ++ KL+ +++ +++L E+L + +EK
Sbjct: 313 EKIMNELSQLKQEKEEKENELKEQVKKMEEEKSKLITELSNGSDGISKLNEELTQTKQEK 372
Query: 614 QDLEKRV 594
+++ +
Sbjct: 373 EEINNEL 379
>ref|XP_009343332.1| PREDICTED: myosin-2 heavy chain-like isoform X3 [Pyrus x
bretschneideri]
Length = 807
Score = 108 bits (270), Expect = 2e-20
Identities = 143/567 (25%), Positives = 260/567 (45%), Gaps = 65/567 (11%)
Frame = -3
Query: 2075 LESKVSVFEAAIATLNDELLNEKDDKKCI-----VNDRNI--LEAAKQALEYKVADLEAA 1917
LE K+ E+ L++EL KD K+ + +N+ + LE A + ++ + DLEA
Sbjct: 109 LEKKLEQSESRKKELSEELQKIKDKKEELEEILDINEAEMEELEEALEKIKTEKEDLEAE 168
Query: 1916 KTTLNDELERKKDDNNAIIKKALDKRISDLKADAPQ-RDQEDDMNALIXXXXXXXXXXXX 1740
K L DEL + + D KKA +K++ DL++D Q ++ + D+ +I
Sbjct: 169 KEALEDELAQIEVD-----KKAFNKKVLDLQSDVDQNKEHQIDLEKMIEQCEAQKKELKE 223
Query: 1739 XXKIVSNLEVNILILHEELQK---EKD-DKTALIKDLVAAEPGKRTVNEIVSHLESKSRS 1572
+ EV + EL K +KD +K AL++ L E K + I++ +++ +
Sbjct: 224 E---LEESEVQLQHTKNELGKVIEQKDAEKVALMQKLGKTEASKVELMIIIALRDAEKKD 280
Query: 1571 LKEHFLREEE--DEVLERSASNLAIMKAIREEELRKEKDGKS---------ALVENGEGC 1425
L +H E DE+ + A +A+RE+ L+ + + K L +
Sbjct: 281 LTKHLDNTEAQIDELEKDLEQTEADKEALREKVLQLQNEAKMNKQLRMKVLELQNVADQN 340
Query: 1424 EAEKQGLEKTVLERRASNLDTMDAIHEEELRKE--KVDKSALTENGEGCEAEKQGPEKTV 1251
+ K LEK + + + + + + E E KE + +K L E+ E EAEK+ E
Sbjct: 341 KKLKNDLEKKLEQSESQKEELREELEEIEAEKEALQAEKEGLEEDLEKIEAEKEDLEAIE 400
Query: 1250 LDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLEAS 1071
+ E + + +AL+ ++ ++ A+K+AL K+ +L+ + D + H+ ++E+K+E S
Sbjct: 401 AEKE-DLEAEKEALEDEIVQIKADKKALNKKVLELQTE----IDQNKEHQNDLEKKIEQS 455
Query: 1070 NLTHND---ELHKEKDDKKSIMNDLDRV----KAEKQVLESKVSDLETTYSTLNNELQQ- 915
+ EL + + + + N+L++V AEK+ L K+ E L L++
Sbjct: 456 EAQKKELKGELEENETQLQQMKNELEKVIEQKDAEKEALMIKLRQTEAGKGELKKSLERF 515
Query: 914 --------KMDDNEA---------FLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKD 786
KM + ++ F + E+ K+ LEK V D + D+ K+
Sbjct: 516 GMELQELTKMSEEKSHRFITLENDFQKRLEQSESQKKELEKMVEDGNSQNEDLM----KE 571
Query: 785 DDYNEAEKQTLKKRISELEEAISILTDKA----KKLLKDINIWLSEVTEL--QEDLNKES 624
+ +AEK L + + +A D A KK L++I + ++ EL + DLNKE
Sbjct: 572 LEKIQAEKINLNIALEQKNKAYK---DGAFLFRKKQLENIEL-TKKMAELEGEADLNKEL 627
Query: 623 K-------EKQDLEKRVLELT--SKLE 570
+ E+ + +K+ LE T KLE
Sbjct: 628 EINFERELERNECQKKELEQTRAEKLE 654
Score = 92.4 bits (228), Expect = 1e-15
Identities = 128/501 (25%), Positives = 219/501 (43%), Gaps = 10/501 (1%)
Frame = -3
Query: 2066 KVSVFEAAIATLNDELLNEKD-DKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELE 1890
K+ FEA +++ ++D + K + I E LE +A EA K TL +L
Sbjct: 17 KIEKFEAQQTVELKKIIVQRDAENKELAKHLEITEDQINELEKHLAQTEADKETLMKKLL 76
Query: 1889 RKKDDNNAIIKKALDKRISDLKADAPQRDQ-EDDMNALIXXXXXXXXXXXXXXKIVSNLE 1713
+ N A I K L ++ +L+ A Q + ++D+ + E
Sbjct: 77 GLQ--NEAKINKQLSMKVLELQNVADQNKKLKNDLEKKL-----------------EQSE 117
Query: 1712 VNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEV 1533
L EELQK KD K L + L E + E + ++++ L+ EDE+
Sbjct: 118 SRKKELSEELQKIKDKKEELEEILDINEAEMEELEEALEKIKTEKEDLEAE-KEALEDEL 176
Query: 1532 LERSASNLAIMKAIRE--EELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTM 1359
+ A K + + ++ + K+ + L + E CEA+K+ L++ + E T
Sbjct: 177 AQIEVDKKAFNKKVLDLQSDVDQNKEHQIDLEKMIEQCEAQKKELKEELEESEVQLQHTK 236
Query: 1358 DAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDL----DR 1191
+ + + + ++ +K AL + EA K ++L I +L DA ++DL D
Sbjct: 237 NELGKV-IEQKDAEKVALMQKLGKTEASK-------VELMIII-ALRDAEKKDLTKHLDN 287
Query: 1190 VMAEKQALEKRCSDLEAKNASLTDN--QEGHEAEIERKLEASNLTHNDELHKEKDDKKSI 1017
A+ LEK EA +L + Q +EA++ ++L L EL D K +
Sbjct: 288 TEAQIDELEKDLEQTEADKEALREKVLQLQNEAKMNKQLRMKVL----ELQNVADQNKKL 343
Query: 1016 MNDLDRVKAEKQVLESKVSDLETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRV 837
NDL E K+ E+ L EL++ + EA E++GLE + LEK
Sbjct: 344 KNDL----------EKKLEQSESQKEELREELEEIEAEKEALQAEKEGLE---EDLEK-- 388
Query: 836 LDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEV 657
+EA D+E + +D EAEK+ L+ +E + I DK K +N +V
Sbjct: 389 --IEAEKEDLEAIEAEKEDL-EAEKEALE------DEIVQIKADK-----KALN---KKV 431
Query: 656 TELQEDLNKESKEKQDLEKRV 594
ELQ ++++ + + DLEK++
Sbjct: 432 LELQTEIDQNKEHQNDLEKKI 452
Score = 77.0 bits (188), Expect = 6e-11
Identities = 90/403 (22%), Positives = 177/403 (43%), Gaps = 28/403 (6%)
Frame = -3
Query: 1691 EELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASN 1512
E+++K + +T +K ++ + E+ HLE + E + E E + + A
Sbjct: 16 EKIEKFEAQQTVELKKIIVQRDAEN--KELAKHLE-----ITEDQINELEKHLAQTEADK 68
Query: 1511 LAIMKAI----REEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHE 1344
+MK + E ++ K+ K ++N A++ K LE++ ++
Sbjct: 69 ETLMKKLLGLQNEAKINKQLSMKVLELQN----VADQNKKLKNDLEKKLEQSESRKKELS 124
Query: 1343 EELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLN---DALQRDLDRVMAEKQ 1173
EEL+K K K L E + EAE + E+ + ++ L +AL+ +L ++ +K+
Sbjct: 125 EELQKIKDKKEELEEILDINEAEMEELEEALEKIKTEKEDLEAEKEALEDELAQIEVDKK 184
Query: 1172 ALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASNLTHNDELHKEKDDKKSIMNDLDRVK 993
A K+ DL++ D + H+ ++E+ +E KK + +L+ +
Sbjct: 185 AFNKKVLDLQSD----VDQNKEHQIDLEKMIEQCEA-----------QKKELKEELEESE 229
Query: 992 AEKQVLESKVSDLETTYSTLNNELQQKMDDNEAFLNERDGL----EAVKQGLEKRVLDLE 825
+ Q ++++ + L QK+ EA E + +A K+ L K + + E
Sbjct: 230 VQLQHTKNELGKVIEQKDAEKVALMQKLGKTEASKVELMIIIALRDAEKKDLTKHLDNTE 289
Query: 824 ATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISI-------------LTDKAKKLLK 684
A I ++E KD + EA+K+ L++++ +L+ + + D+ KKL
Sbjct: 290 AQIDELE----KDLEQTEADKEALREKVLQLQNEAKMNKQLRMKVLELQNVADQNKKLKN 345
Query: 683 DINIWL----SEVTELQEDLNKESKEKQDLEKRVLELTSKLEK 567
D+ L S+ EL+E+L + EK+ L+ L LEK
Sbjct: 346 DLEKKLEQSESQKEELREELEEIEAEKEALQAEKEGLEEDLEK 388
Score = 73.9 bits (180), Expect = 5e-10
Identities = 111/472 (23%), Positives = 209/472 (44%), Gaps = 33/472 (6%)
Frame = -3
Query: 2075 LESKVSVFEAAIATLNDELLN---EKD----DKKCIVNDRNILEAAKQ---ALEYKVADL 1926
LE K+ E+ L +EL EK+ +K+ + D +EA K+ A+E + DL
Sbjct: 347 LEKKLEQSESQKEELREELEEIEAEKEALQAEKEGLEEDLEKIEAEKEDLEAIEAEKEDL 406
Query: 1925 EAAKTTLNDELERKKDDNNAIIKKALDKRISDLKADAPQ-RDQEDDMNALIXXXXXXXXX 1749
EA K L DE+ + K D KKAL+K++ +L+ + Q ++ ++D+ I
Sbjct: 407 EAEKEALEDEIVQIKAD-----KKALNKKVLELQTEIDQNKEHQNDLEKKIEQSEAQKKE 461
Query: 1748 XXXXXKIVSNLEVNILILHEELQK---EKD-DKTALIKDLVAAEPGKRTVNEIVSHLESK 1581
+ E + + EL+K +KD +K AL+ L E GK E+ LE
Sbjct: 462 LKGE---LEENETQLQQMKNELEKVIEQKDAEKEALMIKLRQTEAGK---GELKKSLERF 515
Query: 1580 SRSLKEHFLREEEDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLE 1401
L+E EE + N K + + E +K++ K +VE+G ++ + L
Sbjct: 516 GMELQELTKMSEEKSHRFITLEN-DFQKRLEQSESQKKELEK--MVEDGN---SQNEDLM 569
Query: 1400 KTVLERRASNLDTMDAIHEEE---------LRKEKVDKSALTENGEGCEAEKQGPEKTVL 1248
K + + +A ++ A+ ++ RK++++ LT+ E E ++ +
Sbjct: 570 KELEKIQAEKINLNIALEQKNKAYKDGAFLFRKKQLENIELTKKMAELEGEADLNKELEI 629
Query: 1247 DLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASN 1068
+ E + N+ +++L++ AEK L + + + +L A++E +L N
Sbjct: 630 NFERELER-NECQKKELEQTRAEKLELTFQVEQTKTEKINLMKAL----AQMEMQLHEMN 684
Query: 1067 LTHNDELHKEKDDKKSIMNDLDRVKAEKQVLESKVSDLETTYS--TLNNELQQK------ 912
T E K + S+ + + K+ ++ L+S S+LE + +NEL++K
Sbjct: 685 GTVVLEQQKADELAASLAKERKKRKSYRKKLQSANSELEKKLDGESSSNELEKKLDDVQE 744
Query: 911 -MDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQ 759
NE D E+ LEK++ D++ E++ DD+ E+ +
Sbjct: 745 ESSSNEFEKKLDDVQESAGSELEKKLDDVQKESGSTELEKKVDDEQKESSDE 796
>ref|XP_009343331.1| PREDICTED: myosin-2 heavy chain, non muscle-like isoform X2 [Pyrus x
bretschneideri]
Length = 822
Score = 108 bits (270), Expect = 2e-20
Identities = 143/567 (25%), Positives = 260/567 (45%), Gaps = 65/567 (11%)
Frame = -3
Query: 2075 LESKVSVFEAAIATLNDELLNEKDDKKCI-----VNDRNI--LEAAKQALEYKVADLEAA 1917
LE K+ E+ L++EL KD K+ + +N+ + LE A + ++ + DLEA
Sbjct: 109 LEKKLEQSESRKKELSEELQKIKDKKEELEEILDINEAEMEELEEALEKIKTEKEDLEAE 168
Query: 1916 KTTLNDELERKKDDNNAIIKKALDKRISDLKADAPQ-RDQEDDMNALIXXXXXXXXXXXX 1740
K L DEL + + D KKA +K++ DL++D Q ++ + D+ +I
Sbjct: 169 KEALEDELAQIEVD-----KKAFNKKVLDLQSDVDQNKEHQIDLEKMIEQCEAQKKELKE 223
Query: 1739 XXKIVSNLEVNILILHEELQK---EKD-DKTALIKDLVAAEPGKRTVNEIVSHLESKSRS 1572
+ EV + EL K +KD +K AL++ L E K + I++ +++ +
Sbjct: 224 E---LEESEVQLQHTKNELGKVIEQKDAEKVALMQKLGKTEASKVELMIIIALRDAEKKD 280
Query: 1571 LKEHFLREEE--DEVLERSASNLAIMKAIREEELRKEKDGKS---------ALVENGEGC 1425
L +H E DE+ + A +A+RE+ L+ + + K L +
Sbjct: 281 LTKHLDNTEAQIDELEKDLEQTEADKEALREKVLQLQNEAKMNKQLRMKVLELQNVADQN 340
Query: 1424 EAEKQGLEKTVLERRASNLDTMDAIHEEELRKE--KVDKSALTENGEGCEAEKQGPEKTV 1251
+ K LEK + + + + + + E E KE + +K L E+ E EAEK+ E
Sbjct: 341 KKLKNDLEKKLEQSESQKEELREELEEIEAEKEALQAEKEGLEEDLEKIEAEKEDLEAIE 400
Query: 1250 LDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLEAS 1071
+ E + + +AL+ ++ ++ A+K+AL K+ +L+ + D + H+ ++E+K+E S
Sbjct: 401 AEKE-DLEAEKEALEDEIVQIKADKKALNKKVLELQTE----IDQNKEHQNDLEKKIEQS 455
Query: 1070 NLTHND---ELHKEKDDKKSIMNDLDRV----KAEKQVLESKVSDLETTYSTLNNELQQ- 915
+ EL + + + + N+L++V AEK+ L K+ E L L++
Sbjct: 456 EAQKKELKGELEENETQLQQMKNELEKVIEQKDAEKEALMIKLRQTEAGKGELKKSLERF 515
Query: 914 --------KMDDNEA---------FLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKD 786
KM + ++ F + E+ K+ LEK V D + D+ K+
Sbjct: 516 GMELQELTKMSEEKSHRFITLENDFQKRLEQSESQKKELEKMVEDGNSQNEDLM----KE 571
Query: 785 DDYNEAEKQTLKKRISELEEAISILTDKA----KKLLKDINIWLSEVTEL--QEDLNKES 624
+ +AEK L + + +A D A KK L++I + ++ EL + DLNKE
Sbjct: 572 LEKIQAEKINLNIALEQKNKAYK---DGAFLFRKKQLENIEL-TKKMAELEGEADLNKEL 627
Query: 623 K-------EKQDLEKRVLELT--SKLE 570
+ E+ + +K+ LE T KLE
Sbjct: 628 EINFERELERNECQKKELEQTRAEKLE 654
Score = 92.4 bits (228), Expect = 1e-15
Identities = 128/501 (25%), Positives = 219/501 (43%), Gaps = 10/501 (1%)
Frame = -3
Query: 2066 KVSVFEAAIATLNDELLNEKD-DKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELE 1890
K+ FEA +++ ++D + K + I E LE +A EA K TL +L
Sbjct: 17 KIEKFEAQQTVELKKIIVQRDAENKELAKHLEITEDQINELEKHLAQTEADKETLMKKLL 76
Query: 1889 RKKDDNNAIIKKALDKRISDLKADAPQRDQ-EDDMNALIXXXXXXXXXXXXXXKIVSNLE 1713
+ N A I K L ++ +L+ A Q + ++D+ + E
Sbjct: 77 GLQ--NEAKINKQLSMKVLELQNVADQNKKLKNDLEKKL-----------------EQSE 117
Query: 1712 VNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEV 1533
L EELQK KD K L + L E + E + ++++ L+ EDE+
Sbjct: 118 SRKKELSEELQKIKDKKEELEEILDINEAEMEELEEALEKIKTEKEDLEAE-KEALEDEL 176
Query: 1532 LERSASNLAIMKAIRE--EELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTM 1359
+ A K + + ++ + K+ + L + E CEA+K+ L++ + E T
Sbjct: 177 AQIEVDKKAFNKKVLDLQSDVDQNKEHQIDLEKMIEQCEAQKKELKEELEESEVQLQHTK 236
Query: 1358 DAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDL----DR 1191
+ + + + ++ +K AL + EA K ++L I +L DA ++DL D
Sbjct: 237 NELGKV-IEQKDAEKVALMQKLGKTEASK-------VELMIII-ALRDAEKKDLTKHLDN 287
Query: 1190 VMAEKQALEKRCSDLEAKNASLTDN--QEGHEAEIERKLEASNLTHNDELHKEKDDKKSI 1017
A+ LEK EA +L + Q +EA++ ++L L EL D K +
Sbjct: 288 TEAQIDELEKDLEQTEADKEALREKVLQLQNEAKMNKQLRMKVL----ELQNVADQNKKL 343
Query: 1016 MNDLDRVKAEKQVLESKVSDLETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRV 837
NDL E K+ E+ L EL++ + EA E++GLE + LEK
Sbjct: 344 KNDL----------EKKLEQSESQKEELREELEEIEAEKEALQAEKEGLE---EDLEK-- 388
Query: 836 LDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEV 657
+EA D+E + +D EAEK+ L+ +E + I DK K +N +V
Sbjct: 389 --IEAEKEDLEAIEAEKEDL-EAEKEALE------DEIVQIKADK-----KALN---KKV 431
Query: 656 TELQEDLNKESKEKQDLEKRV 594
ELQ ++++ + + DLEK++
Sbjct: 432 LELQTEIDQNKEHQNDLEKKI 452
Score = 77.0 bits (188), Expect = 6e-11
Identities = 90/403 (22%), Positives = 177/403 (43%), Gaps = 28/403 (6%)
Frame = -3
Query: 1691 EELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASN 1512
E+++K + +T +K ++ + E+ HLE + E + E E + + A
Sbjct: 16 EKIEKFEAQQTVELKKIIVQRDAEN--KELAKHLE-----ITEDQINELEKHLAQTEADK 68
Query: 1511 LAIMKAI----REEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHE 1344
+MK + E ++ K+ K ++N A++ K LE++ ++
Sbjct: 69 ETLMKKLLGLQNEAKINKQLSMKVLELQN----VADQNKKLKNDLEKKLEQSESRKKELS 124
Query: 1343 EELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLN---DALQRDLDRVMAEKQ 1173
EEL+K K K L E + EAE + E+ + ++ L +AL+ +L ++ +K+
Sbjct: 125 EELQKIKDKKEELEEILDINEAEMEELEEALEKIKTEKEDLEAEKEALEDELAQIEVDKK 184
Query: 1172 ALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASNLTHNDELHKEKDDKKSIMNDLDRVK 993
A K+ DL++ D + H+ ++E+ +E KK + +L+ +
Sbjct: 185 AFNKKVLDLQSD----VDQNKEHQIDLEKMIEQCEA-----------QKKELKEELEESE 229
Query: 992 AEKQVLESKVSDLETTYSTLNNELQQKMDDNEAFLNERDGL----EAVKQGLEKRVLDLE 825
+ Q ++++ + L QK+ EA E + +A K+ L K + + E
Sbjct: 230 VQLQHTKNELGKVIEQKDAEKVALMQKLGKTEASKVELMIIIALRDAEKKDLTKHLDNTE 289
Query: 824 ATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISI-------------LTDKAKKLLK 684
A I ++E KD + EA+K+ L++++ +L+ + + D+ KKL
Sbjct: 290 AQIDELE----KDLEQTEADKEALREKVLQLQNEAKMNKQLRMKVLELQNVADQNKKLKN 345
Query: 683 DINIWL----SEVTELQEDLNKESKEKQDLEKRVLELTSKLEK 567
D+ L S+ EL+E+L + EK+ L+ L LEK
Sbjct: 346 DLEKKLEQSESQKEELREELEEIEAEKEALQAEKEGLEEDLEK 388
Score = 69.3 bits (168), Expect = 1e-08
Identities = 113/487 (23%), Positives = 211/487 (43%), Gaps = 48/487 (9%)
Frame = -3
Query: 2075 LESKVSVFEAAIATLNDELLN---EKD----DKKCIVNDRNILEAAKQ---ALEYKVADL 1926
LE K+ E+ L +EL EK+ +K+ + D +EA K+ A+E + DL
Sbjct: 347 LEKKLEQSESQKEELREELEEIEAEKEALQAEKEGLEEDLEKIEAEKEDLEAIEAEKEDL 406
Query: 1925 EAAKTTLNDELERKKDDNNAIIKKALDKRISDLKADAPQ-RDQEDDMNALIXXXXXXXXX 1749
EA K L DE+ + K D KKAL+K++ +L+ + Q ++ ++D+ I
Sbjct: 407 EAEKEALEDEIVQIKAD-----KKALNKKVLELQTEIDQNKEHQNDLEKKIEQSEAQKKE 461
Query: 1748 XXXXXKIVSNLEVNILILHEELQK---EKD-DKTALIKDLVAAEPGKRTVNEIVSHLESK 1581
+ E + + EL+K +KD +K AL+ L E GK E+ LE
Sbjct: 462 LKGE---LEENETQLQQMKNELEKVIEQKDAEKEALMIKLRQTEAGK---GELKKSLERF 515
Query: 1580 SRSLKEHFLREEEDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLE 1401
L+E EE + N K + + E +K++ K +VE+G ++ + L
Sbjct: 516 GMELQELTKMSEEKSHRFITLEN-DFQKRLEQSESQKKELEK--MVEDGN---SQNEDLM 569
Query: 1400 KTVLERRASNLDTMDAIHEEE---------LRKEKVDKSALTENGEGCEAEKQGPEKTVL 1248
K + + +A ++ A+ ++ RK++++ LT+ E E ++ +
Sbjct: 570 KELEKIQAEKINLNIALEQKNKAYKDGAFLFRKKQLENIELTKKMAELEGEADLNKELEI 629
Query: 1247 DLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASN 1068
+ E + N+ +++L++ AEK L + + + +L A++E +L N
Sbjct: 630 NFERELER-NECQKKELEQTRAEKLELTFQVEQTKTEKINLMKAL----AQMEMQLHEMN 684
Query: 1067 LT------HNDELH----KEKDDKKSIMNDLDRVKAEKQV----------LESKVSDLET 948
T DEL KE+ +KS L +E + LE K+ D++
Sbjct: 685 GTVVLEQQKADELAASLAKERKKRKSYRKKLQSANSELEKKLDGESANSELEKKLVDVQE 744
Query: 947 TYST----LNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDD 780
+ S +++Q++ NE D E+ LEK++ D++ E++ DD+
Sbjct: 745 SSSNELEKKLDDVQEESSSNEFEKKLDDVQESAGSELEKKLDDVQKESGSTELEKKVDDE 804
Query: 779 YNEAEKQ 759
E+ +
Sbjct: 805 QKESSDE 811
>ref|XP_009343330.1| PREDICTED: myosin heavy chain, embryonic smooth muscle isoform-like
isoform X1 [Pyrus x bretschneideri]
Length = 840
Score = 108 bits (270), Expect = 2e-20
Identities = 143/567 (25%), Positives = 260/567 (45%), Gaps = 65/567 (11%)
Frame = -3
Query: 2075 LESKVSVFEAAIATLNDELLNEKDDKKCI-----VNDRNI--LEAAKQALEYKVADLEAA 1917
LE K+ E+ L++EL KD K+ + +N+ + LE A + ++ + DLEA
Sbjct: 109 LEKKLEQSESRKKELSEELQKIKDKKEELEEILDINEAEMEELEEALEKIKTEKEDLEAE 168
Query: 1916 KTTLNDELERKKDDNNAIIKKALDKRISDLKADAPQ-RDQEDDMNALIXXXXXXXXXXXX 1740
K L DEL + + D KKA +K++ DL++D Q ++ + D+ +I
Sbjct: 169 KEALEDELAQIEVD-----KKAFNKKVLDLQSDVDQNKEHQIDLEKMIEQCEAQKKELKE 223
Query: 1739 XXKIVSNLEVNILILHEELQK---EKD-DKTALIKDLVAAEPGKRTVNEIVSHLESKSRS 1572
+ EV + EL K +KD +K AL++ L E K + I++ +++ +
Sbjct: 224 E---LEESEVQLQHTKNELGKVIEQKDAEKVALMQKLGKTEASKVELMIIIALRDAEKKD 280
Query: 1571 LKEHFLREEE--DEVLERSASNLAIMKAIREEELRKEKDGKS---------ALVENGEGC 1425
L +H E DE+ + A +A+RE+ L+ + + K L +
Sbjct: 281 LTKHLDNTEAQIDELEKDLEQTEADKEALREKVLQLQNEAKMNKQLRMKVLELQNVADQN 340
Query: 1424 EAEKQGLEKTVLERRASNLDTMDAIHEEELRKE--KVDKSALTENGEGCEAEKQGPEKTV 1251
+ K LEK + + + + + + E E KE + +K L E+ E EAEK+ E
Sbjct: 341 KKLKNDLEKKLEQSESQKEELREELEEIEAEKEALQAEKEGLEEDLEKIEAEKEDLEAIE 400
Query: 1250 LDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLEAS 1071
+ E + + +AL+ ++ ++ A+K+AL K+ +L+ + D + H+ ++E+K+E S
Sbjct: 401 AEKE-DLEAEKEALEDEIVQIKADKKALNKKVLELQTE----IDQNKEHQNDLEKKIEQS 455
Query: 1070 NLTHND---ELHKEKDDKKSIMNDLDRV----KAEKQVLESKVSDLETTYSTLNNELQQ- 915
+ EL + + + + N+L++V AEK+ L K+ E L L++
Sbjct: 456 EAQKKELKGELEENETQLQQMKNELEKVIEQKDAEKEALMIKLRQTEAGKGELKKSLERF 515
Query: 914 --------KMDDNEA---------FLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKD 786
KM + ++ F + E+ K+ LEK V D + D+ K+
Sbjct: 516 GMELQELTKMSEEKSHRFITLENDFQKRLEQSESQKKELEKMVEDGNSQNEDLM----KE 571
Query: 785 DDYNEAEKQTLKKRISELEEAISILTDKA----KKLLKDINIWLSEVTEL--QEDLNKES 624
+ +AEK L + + +A D A KK L++I + ++ EL + DLNKE
Sbjct: 572 LEKIQAEKINLNIALEQKNKAYK---DGAFLFRKKQLENIEL-TKKMAELEGEADLNKEL 627
Query: 623 K-------EKQDLEKRVLELT--SKLE 570
+ E+ + +K+ LE T KLE
Sbjct: 628 EINFERELERNECQKKELEQTRAEKLE 654
Score = 92.4 bits (228), Expect = 1e-15
Identities = 128/501 (25%), Positives = 219/501 (43%), Gaps = 10/501 (1%)
Frame = -3
Query: 2066 KVSVFEAAIATLNDELLNEKD-DKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELE 1890
K+ FEA +++ ++D + K + I E LE +A EA K TL +L
Sbjct: 17 KIEKFEAQQTVELKKIIVQRDAENKELAKHLEITEDQINELEKHLAQTEADKETLMKKLL 76
Query: 1889 RKKDDNNAIIKKALDKRISDLKADAPQRDQ-EDDMNALIXXXXXXXXXXXXXXKIVSNLE 1713
+ N A I K L ++ +L+ A Q + ++D+ + E
Sbjct: 77 GLQ--NEAKINKQLSMKVLELQNVADQNKKLKNDLEKKL-----------------EQSE 117
Query: 1712 VNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEV 1533
L EELQK KD K L + L E + E + ++++ L+ EDE+
Sbjct: 118 SRKKELSEELQKIKDKKEELEEILDINEAEMEELEEALEKIKTEKEDLEAE-KEALEDEL 176
Query: 1532 LERSASNLAIMKAIRE--EELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTM 1359
+ A K + + ++ + K+ + L + E CEA+K+ L++ + E T
Sbjct: 177 AQIEVDKKAFNKKVLDLQSDVDQNKEHQIDLEKMIEQCEAQKKELKEELEESEVQLQHTK 236
Query: 1358 DAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDL----DR 1191
+ + + + ++ +K AL + EA K ++L I +L DA ++DL D
Sbjct: 237 NELGKV-IEQKDAEKVALMQKLGKTEASK-------VELMIII-ALRDAEKKDLTKHLDN 287
Query: 1190 VMAEKQALEKRCSDLEAKNASLTDN--QEGHEAEIERKLEASNLTHNDELHKEKDDKKSI 1017
A+ LEK EA +L + Q +EA++ ++L L EL D K +
Sbjct: 288 TEAQIDELEKDLEQTEADKEALREKVLQLQNEAKMNKQLRMKVL----ELQNVADQNKKL 343
Query: 1016 MNDLDRVKAEKQVLESKVSDLETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRV 837
NDL E K+ E+ L EL++ + EA E++GLE + LEK
Sbjct: 344 KNDL----------EKKLEQSESQKEELREELEEIEAEKEALQAEKEGLE---EDLEK-- 388
Query: 836 LDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEV 657
+EA D+E + +D EAEK+ L+ +E + I DK K +N +V
Sbjct: 389 --IEAEKEDLEAIEAEKEDL-EAEKEALE------DEIVQIKADK-----KALN---KKV 431
Query: 656 TELQEDLNKESKEKQDLEKRV 594
ELQ ++++ + + DLEK++
Sbjct: 432 LELQTEIDQNKEHQNDLEKKI 452
Score = 77.0 bits (188), Expect = 6e-11
Identities = 90/403 (22%), Positives = 177/403 (43%), Gaps = 28/403 (6%)
Frame = -3
Query: 1691 EELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASN 1512
E+++K + +T +K ++ + E+ HLE + E + E E + + A
Sbjct: 16 EKIEKFEAQQTVELKKIIVQRDAEN--KELAKHLE-----ITEDQINELEKHLAQTEADK 68
Query: 1511 LAIMKAI----REEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHE 1344
+MK + E ++ K+ K ++N A++ K LE++ ++
Sbjct: 69 ETLMKKLLGLQNEAKINKQLSMKVLELQN----VADQNKKLKNDLEKKLEQSESRKKELS 124
Query: 1343 EELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLN---DALQRDLDRVMAEKQ 1173
EEL+K K K L E + EAE + E+ + ++ L +AL+ +L ++ +K+
Sbjct: 125 EELQKIKDKKEELEEILDINEAEMEELEEALEKIKTEKEDLEAEKEALEDELAQIEVDKK 184
Query: 1172 ALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASNLTHNDELHKEKDDKKSIMNDLDRVK 993
A K+ DL++ D + H+ ++E+ +E KK + +L+ +
Sbjct: 185 AFNKKVLDLQSD----VDQNKEHQIDLEKMIEQCEA-----------QKKELKEELEESE 229
Query: 992 AEKQVLESKVSDLETTYSTLNNELQQKMDDNEAFLNERDGL----EAVKQGLEKRVLDLE 825
+ Q ++++ + L QK+ EA E + +A K+ L K + + E
Sbjct: 230 VQLQHTKNELGKVIEQKDAEKVALMQKLGKTEASKVELMIIIALRDAEKKDLTKHLDNTE 289
Query: 824 ATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISI-------------LTDKAKKLLK 684
A I ++E KD + EA+K+ L++++ +L+ + + D+ KKL
Sbjct: 290 AQIDELE----KDLEQTEADKEALREKVLQLQNEAKMNKQLRMKVLELQNVADQNKKLKN 345
Query: 683 DINIWL----SEVTELQEDLNKESKEKQDLEKRVLELTSKLEK 567
D+ L S+ EL+E+L + EK+ L+ L LEK
Sbjct: 346 DLEKKLEQSESQKEELREELEEIEAEKEALQAEKEGLEEDLEK 388
Score = 71.2 bits (173), Expect = 3e-09
Identities = 117/507 (23%), Positives = 215/507 (42%), Gaps = 68/507 (13%)
Frame = -3
Query: 2075 LESKVSVFEAAIATLNDELLN---EKD----DKKCIVNDRNILEAAKQ---ALEYKVADL 1926
LE K+ E+ L +EL EK+ +K+ + D +EA K+ A+E + DL
Sbjct: 347 LEKKLEQSESQKEELREELEEIEAEKEALQAEKEGLEEDLEKIEAEKEDLEAIEAEKEDL 406
Query: 1925 EAAKTTLNDELERKKDDNNAIIKKALDKRISDLKADAPQ-RDQEDDMNALIXXXXXXXXX 1749
EA K L DE+ + K D KKAL+K++ +L+ + Q ++ ++D+ I
Sbjct: 407 EAEKEALEDEIVQIKAD-----KKALNKKVLELQTEIDQNKEHQNDLEKKIEQSEAQKKE 461
Query: 1748 XXXXXKIVSNLEVNILILHEELQK---EKD-DKTALIKDLVAAEPGK-----------RT 1614
+ E + + EL+K +KD +K AL+ L E GK
Sbjct: 462 LKGE---LEENETQLQQMKNELEKVIEQKDAEKEALMIKLRQTEAGKGELKKSLERFGME 518
Query: 1613 VNEIVSHLESKSRSL-------------KEHFLREEEDEVLERSASNLAIMKAIREEELR 1473
+ E+ E KS E +E E V + ++ N +MK + E+++
Sbjct: 519 LQELTKMSEEKSHRFITLENDFQKRLEQSESQKKELEKMVEDGNSQNEDLMKEL--EKIQ 576
Query: 1472 KEK-------DGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHEE--------- 1341
EK + K+ ++G +KQ LE L ++ + L+ +++E
Sbjct: 577 AEKINLNIALEQKNKAYKDGAFLFRKKQ-LENIELTKKMAELEGEADLNKELEINFEREL 635
Query: 1340 --------ELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVM 1185
EL + + +K LT E + EK K + +E + +N V+
Sbjct: 636 ERNECQKKELEQTRAEKLELTFQVEQTKTEKINLMKALAQMEMQLHEMNGT-------VV 688
Query: 1184 AEKQALEKRCSDL---EAKNASLTDNQEGHEAEIERKLEA-SNLTHNDELHKEKDD-KKS 1020
E+Q ++ + L K S + +E+E+KL+ + EL K+ DD ++S
Sbjct: 689 LEQQKADELAASLAKERKKRKSYRKKLQSANSELEKKLDGVQKKSAGSELEKKLDDVQES 748
Query: 1019 IMNDLDRVKAEKQVLESKVSDLETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKR 840
++L++ + Q ES ++LE +++Q++ NE D E+ LEK+
Sbjct: 749 ANSELEKKLVDVQ--ESSSNELEKKL----DDVQEESSSNEFEKKLDDVQESAGSELEKK 802
Query: 839 VLDLEATIHDIEMKTGKDDDYNEAEKQ 759
+ D++ E++ DD+ E+ +
Sbjct: 803 LDDVQKESGSTELEKKVDDEQKESSDE 829
>ref|XP_009343342.1| PREDICTED: myosin-10-like [Pyrus x bretschneideri]
Length = 889
Score = 107 bits (266), Expect = 6e-20
Identities = 142/560 (25%), Positives = 254/560 (45%), Gaps = 58/560 (10%)
Frame = -3
Query: 2075 LESKVSVFEAAIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDE 1896
LE K+ E+ L++EL KD K+ + +I E K+ DLEA K L DE
Sbjct: 172 LEKKLEQSESRKKELSEELQKIKDKKEELEEILDINETEKE-------DLEAEKEALEDE 224
Query: 1895 LERKKDDNNAIIKKALDKRISDLKADAPQ-RDQEDDMNALIXXXXXXXXXXXXXXKIVSN 1719
L + + D KKA +K++ DL++D Q ++ + D+ +I +
Sbjct: 225 LAQIEVD-----KKAFNKKVLDLQSDVDQNKEHQIDLEKMIEQCEAQKKELKEE---LEE 276
Query: 1718 LEVNILILHEELQK---EKD-DKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLR 1551
EV + EL K +KD +K AL++ L E K + I++ +++ + L +H
Sbjct: 277 SEVQLQHTKNELGKVIEQKDAEKVALMQKLGKTEASKVELMIIIALRDAEKKDLTKHLDN 336
Query: 1550 EEE--DEVLERSASNLAIMKAIREEELRKEKDGKS---------ALVENGEGCEAEKQGL 1404
E DE+ + A +A+RE+ L+ + + K L + + K L
Sbjct: 337 TEAQIDELEKDLEQTEADKEALREKVLQLQNEAKMNKQLRMKVLELQNVADQNKKLKNDL 396
Query: 1403 EKTVLERRASNLDTMDAIHEEELRKE--KVDKSALTENGEGCEAEKQGPEKTVLDLEPTI 1230
EK + + + + + + E E KE + +K L E+ E EAEK+ E + E +
Sbjct: 397 EKKLEQSESQKEELREELEEIEAEKEALQAEKEGLEEDLEKIEAEKEDLEAIEAEKE-DL 455
Query: 1229 PSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASNLTHND- 1053
+ +AL+ ++ ++ A+K+AL K+ +L+ + D + H+ ++E+K+E S +
Sbjct: 456 EAEKEALEDEIVQIKADKKALNKKVLELQTE----IDQNKEHQNDLEKKIEQSEAQKKEL 511
Query: 1052 --ELHKEKDDKKSIMNDLDRV----KAEKQVLESKVSDLETTYSTLNNELQQ-------- 915
EL + + + + N+L++V AEK+ L K+ E L L++
Sbjct: 512 KGELEENETQLQQMKNELEKVIEQKDAEKEALMIKLRQTEAGKGELKKSLERFGMELQEL 571
Query: 914 -KMDDNEA---------FLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAE 765
KM + ++ F + E+ K+ LEK V D + D+ K+ + +AE
Sbjct: 572 TKMSEEKSHRFITLENDFQKRLEQSESQKKELEKMVEDGNSQNEDLM----KELEKIQAE 627
Query: 764 KQTLKKRISELEEAISILTDKA----KKLLKDINIWLSEVTEL--QEDLNKESK------ 621
K L + + +A D A KK L++I + ++ EL + DLNKE +
Sbjct: 628 KINLNIALEQKNKAYK---DGAFLFRKKQLENIEL-TKKMAELEGEADLNKELEINFERE 683
Query: 620 -EKQDLEKRVLELT--SKLE 570
E+ + +K+ LE T KLE
Sbjct: 684 LERNECQKKELEQTRAEKLE 703
Score = 91.3 bits (225), Expect = 3e-15
Identities = 108/412 (26%), Positives = 190/412 (46%), Gaps = 44/412 (10%)
Frame = -3
Query: 1697 LHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSH--LESKSRSLKEHFLREEEDEVLER 1524
L + L + + DK L+K L+ + + +N+ +S LE ++ + + L+ + ++ LE+
Sbjct: 120 LEKHLAQTEADKETLMKKLLGLQ-NEAKINKQLSMKVLELQNVADQNKKLKNDLEKKLEQ 178
Query: 1523 SASNLAIMKAIREEELRKEKDGKSALVE-------NGEGCEAEKQGLEKTV----LERRA 1377
S S K EEL+K KD K L E E EAEK+ LE + ++++A
Sbjct: 179 SESR----KKELSEELQKIKDKKEELEEILDINETEKEDLEAEKEALEDELAQIEVDKKA 234
Query: 1376 SNLDTMDAIHEEELRKE-KVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRD 1200
N +D + + KE ++D + E CEA+K+ ++ + + E + + L +
Sbjct: 235 FNKKVLDLQSDVDQNKEHQIDLEKMIEQ---CEAQKKELKEELEESEVQLQHTKNELGKV 291
Query: 1199 LDRVMAEKQALEKRCSDLEAKNASLT-----------------DNQEGHEAEIERKLEAS 1071
+++ AEK AL ++ EA L DN E E+E+ LE +
Sbjct: 292 IEQKDAEKVALMQKLGKTEASKVELMIIIALRDAEKKDLTKHLDNTEAQIDELEKDLEQT 351
Query: 1070 N------------LTHNDELHKEKDDKK-SIMNDLDRVKAEKQVLESKVSDLETTYSTLN 930
L + +++K+ K + N D+ K K LE K+ E+ L
Sbjct: 352 EADKEALREKVLQLQNEAKMNKQLRMKVLELQNVADQNKKLKNDLEKKLEQSESQKEELR 411
Query: 929 NELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLK 750
EL++ + EA E++GLE + LEK +EA D+E + +D EAEK+ L+
Sbjct: 412 EELEEIEAEKEALQAEKEGLE---EDLEK----IEAEKEDLEAIEAEKEDL-EAEKEALE 463
Query: 749 KRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRV 594
+E + I DK K +N +V ELQ ++++ + + DLEK++
Sbjct: 464 ------DEIVQIKADK-----KALN---KKVLELQTEIDQNKEHQNDLEKKI 501
Score = 89.7 bits (221), Expect = 9e-15
Identities = 127/518 (24%), Positives = 234/518 (45%), Gaps = 29/518 (5%)
Frame = -3
Query: 2075 LESKVSVFEAAIATLNDELLN---EKD----DKKCIVNDRNILEAAKQ---ALEYKVADL 1926
LE K+ E+ L +EL EK+ +K+ + D +EA K+ A+E + DL
Sbjct: 396 LEKKLEQSESQKEELREELEEIEAEKEALQAEKEGLEEDLEKIEAEKEDLEAIEAEKEDL 455
Query: 1925 EAAKTTLNDELERKKDDNNAIIKKALDKRISDLKADAPQ-RDQEDDMNALIXXXXXXXXX 1749
EA K L DE+ + K D KKAL+K++ +L+ + Q ++ ++D+ I
Sbjct: 456 EAEKEALEDEIVQIKAD-----KKALNKKVLELQTEIDQNKEHQNDLEKKIEQSEAQKKE 510
Query: 1748 XXXXXKIVSNLEVNILILHEELQK---EKD-DKTALIKDLVAAEPGKRTVNEIVSHLESK 1581
+ E + + EL+K +KD +K AL+ L E GK E+ LE
Sbjct: 511 LKGE---LEENETQLQQMKNELEKVIEQKDAEKEALMIKLRQTEAGK---GELKKSLERF 564
Query: 1580 SRSLKEHFLREEEDE----VLERSASNLAIMKAIREEELRK-EKDGKSA---LVENGEGC 1425
L+E EE LE +++EL K +DG S L++ E
Sbjct: 565 GMELQELTKMSEEKSHRFITLENDFQKRLEQSESQKKELEKMVEDGNSQNEDLMKELEKI 624
Query: 1424 EAEKQGLEKTVLERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLD 1245
+AEK L + ++ + D RK++++ LT+ E E ++ ++
Sbjct: 625 QAEKINLNIALEQKNKAYKDGAFL-----FRKKQLENIELTKKMAELEGEADLNKELEIN 679
Query: 1244 LEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASNL 1065
E + N+ +++L++ AEK L + + + +L A++E +L N
Sbjct: 680 FEREL-ERNECQKKELEQTRAEKLELTFQVEQTKTEKINLMKAL----AQMEMQLHEMNG 734
Query: 1064 THNDELHKEKDDKKSIMNDLDRVKAEKQVLESKVSDLE-----TTYSTLNNELQQKMDDN 900
T E K + S+ + + K+ ++ L+S S+LE + +EL++K+DD
Sbjct: 735 TVVLEQQKADELAASLAKERKKRKSYRKKLQSANSELEKKLDGVQKKSAGSELEKKLDDV 794
Query: 899 EAFLNERDGLEAVKQGLEKRVLDL-EATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEA 723
+ E+ LEK+++D+ E++ +++E K DD E+ +K++ +++E+
Sbjct: 795 Q---------ESANSELEKKLVDVQESSSNELEKKL--DDVQEESSSNEFEKKLDDVQES 843
Query: 722 ISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQD 609
+ +K L D+ S TEL++ ++ E KE D
Sbjct: 844 AG---SELEKKLDDVQ-KESGSTELEKKVDDEQKESSD 877
Score = 75.9 bits (185), Expect = 1e-10
Identities = 91/400 (22%), Positives = 174/400 (43%), Gaps = 25/400 (6%)
Frame = -3
Query: 1691 EELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASN 1512
E+++K + +T +K ++ + E+ HLE + E + E E + + A
Sbjct: 79 EKIEKFEAQQTVELKKIIVQRDAEN--KELAKHLE-----ITEDQINELEKHLAQTEADK 131
Query: 1511 LAIMKAI----REEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHE 1344
+MK + E ++ K+ K ++N A++ K LE++ ++
Sbjct: 132 ETLMKKLLGLQNEAKINKQLSMKVLELQN----VADQNKKLKNDLEKKLEQSESRKKELS 187
Query: 1343 EELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALE 1164
EEL+K K K L E + E EK+ DLE +AL+ +L ++ +K+A
Sbjct: 188 EELQKIKDKKEELEEILDINETEKE-------DLEAE----KEALEDELAQIEVDKKAFN 236
Query: 1163 KRCSDLEAKNASLTDNQEGHEAEIERKLEASNLTHNDELHKEKDDKKSIMNDLDRVKAEK 984
K+ DL++ D + H+ ++E+ +E KK + +L+ + +
Sbjct: 237 KKVLDLQSD----VDQNKEHQIDLEKMIEQCEA-----------QKKELKEELEESEVQL 281
Query: 983 QVLESKVSDLETTYSTLNNELQQKMDDNEAFLNERDGL----EAVKQGLEKRVLDLEATI 816
Q ++++ + L QK+ EA E + +A K+ L K + + EA I
Sbjct: 282 QHTKNELGKVIEQKDAEKVALMQKLGKTEASKVELMIIIALRDAEKKDLTKHLDNTEAQI 341
Query: 815 HDIEMKTGKDDDYNEAEKQTLKKRISELEEAISI-------------LTDKAKKLLKDIN 675
++E KD + EA+K+ L++++ +L+ + + D+ KKL D+
Sbjct: 342 DELE----KDLEQTEADKEALREKVLQLQNEAKMNKQLRMKVLELQNVADQNKKLKNDLE 397
Query: 674 IWL----SEVTELQEDLNKESKEKQDLEKRVLELTSKLEK 567
L S+ EL+E+L + EK+ L+ L LEK
Sbjct: 398 KKLEQSESQKEELREELEEIEAEKEALQAEKEGLEEDLEK 437
>ref|XP_804789.1| R27-2 protein [Trypanosoma cruzi strain CL Brener]
gi|70867933|gb|EAN82938.1| R27-2 protein, putative
[Trypanosoma cruzi]
Length = 1597
Score = 106 bits (264), Expect = 9e-20
Identities = 118/538 (21%), Positives = 231/538 (42%), Gaps = 32/538 (5%)
Frame = -3
Query: 2081 QALESKVSVFEAAIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLN 1902
+ L +++ EA I L ++L + D + + + EA + L ++A EA L
Sbjct: 649 EKLTEELAQREADIEKLAEDLAQREADNEKLTEELAQREADNEKLAEELAQREADIEKLA 708
Query: 1901 DELERKKDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVS 1722
+EL +++ DN + ++ + + K +E D L + ++
Sbjct: 709 EELAQREADNEKLAEELAQREADNEKLTEDLAQREADNEKLTEDLAQREADIEKLTEELA 768
Query: 1721 NLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEE 1542
E +I L EEL + + D L +DLV E + E ++ E+ + L E + E
Sbjct: 769 QREADIEKLTEELVQREADIEKLTEDLVQREADIEKLTEDLAQREADNEKLAEDLAQREA 828
Query: 1541 DEVLERSASNLAIMKAIRE---EELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASN 1371
D E+ +LA +A E E+L + + L E+ EA+ + L + + +R A N
Sbjct: 829 DN--EKLTEDLAQREADNEKLAEDLAQREADNEKLTEDLAQREADNEKLTEDLAQREADN 886
Query: 1370 ------LDTMDAIHE---EELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLN 1218
L +A +E EEL + + D LTE EA+ + + ++ E I L
Sbjct: 887 EKLTEDLAQREADNEKLTEELVQREADNEKLTEELAQREADNEKLTEDLVQREADIEKLT 946
Query: 1217 DALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIER------KLEASNLTHN 1056
+ DL + A+ + L + + EA N LT++ EA+IE+ + EA
Sbjct: 947 E----DLAQREADNEKLTEDLAQREADNEKLTEDLVQREADIEKLTEDLVQREADIEKLT 1002
Query: 1055 DELHKEKDDKKSIMNDLDRVKAEKQVLESKVSDLETTYSTLNNELQQKMDD----NEAFL 888
++L + + D + + DL + +A+ + L ++ E L +L Q+ D E +
Sbjct: 1003 EDLVQREADIEKLTEDLAQREADNEKLTEDLAQREADIEKLTEDLVQREADIEKLTEDLV 1062
Query: 887 NERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDD------YNEAEKQTLKKRISELEE 726
+E + + L +R D E ++ + ++ EA+ + L + +++ E
Sbjct: 1063 QREADIEKLTEDLAQREADNEKLAEELAQREADNEKLAEELVQREADNEKLAEELAQWEA 1122
Query: 725 AISILTDKAKKLLKDINIWLSEVTELQEDLNKESKE----KQDLEKRVLELTSKLEKC 564
L ++ + DI ++ + + D K ++E + D+EK ++L+ K +C
Sbjct: 1123 DNEKLAEELAQREADIEKLTEDLAQREADNEKLAEELVQREADIEKLAVDLSQKEAEC 1180
Score = 73.9 bits (180), Expect = 5e-10
Identities = 91/381 (23%), Positives = 162/381 (42%), Gaps = 4/381 (1%)
Frame = -3
Query: 1703 LILHEELQKEKDDKTALIKDLV-AAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVLE 1527
L+ H E++ + ++ +L +A P N V RS E F DE+ +
Sbjct: 446 LVAHREMRNARINERLSHPELCDSASPQVPPPNTDVPVAPEVVRS--EPFYCVTLDELNK 503
Query: 1526 RSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIH 1347
N + +A+ + E EK L E EA+ + L + +++R A N
Sbjct: 504 TGTLNEQLTRALAQREADNEK-----LTEELAQREADNEKLAEELVQREADNEKLT---- 554
Query: 1346 EEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDAL-QRDLDRVMAEKQA 1170
EEL + D LTE+ EA+ + + + E I L + L QR+ D + +
Sbjct: 555 -EELAHREADIEKLTEDLAQREADIEKLAEDLAQREADIEKLTEELAQREAD-IEKLTEE 612
Query: 1169 LEKRCSDLEAKNASLTDNQEGHEAEIER--KLEASNLTHNDELHKEKDDKKSIMNDLDRV 996
L +R +D+E L + +E E + EA N +EL + + D + + DL +
Sbjct: 613 LAQREADIEKLTEELAQREADNEKLTEELAQREADNEKLTEELAQREADIEKLAEDLAQR 672
Query: 995 KAEKQVLESKVSDLETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATI 816
+A+ + L +++ E L EL Q+ D E E EA + L + + EA
Sbjct: 673 EADNEKLTEELAQREADNEKLAEELAQREADIEKLAEELAQREADNEKLAEELAQREAD- 731
Query: 815 HDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDL 636
K +D EA+ + L + +++ E I LT++ + DI E+ + + D+
Sbjct: 732 ---NEKLTEDLAQREADNEKLTEDLAQREADIEKLTEELAQREADIEKLTEELVQREADI 788
Query: 635 NKESKEKQDLEKRVLELTSKL 573
K +++ E + +LT L
Sbjct: 789 EKLTEDLVQREADIEKLTEDL 809
Score = 60.5 bits (145), Expect = 6e-06
Identities = 105/514 (20%), Positives = 203/514 (39%), Gaps = 38/514 (7%)
Frame = -3
Query: 1994 CIVNDR-NILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKALDKRISDLKAD 1818
C+ D N + L +A EA L +EL +++ DN + ++ + + + K
Sbjct: 122 CVTLDELNKTGTLNEQLTRALAQREADNEKLTEELAQREADNEKLAEELVQREADNEKLT 181
Query: 1817 APQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDKTALIKDLV 1638
+E D L + ++ E + L E+L + + D L +DL
Sbjct: 182 EELAQREADNEKLTEELAQREADNEKLAEELAQREADNEKLTEDLAQREADNEKLAEDLA 241
Query: 1637 AAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNLAIMKAIREEELRKEKDG 1458
E + E ++ E+ + L E + E D +E+ A +LA +A E+L ++
Sbjct: 242 QREADNEKLTEELAQREADNEKLTEELAQREAD--IEKLAEDLAQREA-DNEKLAEDLAQ 298
Query: 1457 KSALVENGE--------GCEAEKQGLEKTVLERRASNLDTMDAIHEE------ELRKEKV 1320
+ A++E E G + + LE+ R + +D + E +L+ +
Sbjct: 299 REAVIEGAEADASKTIEGVYSRCRELEELAARRELAATGDVDILERELADALVQLKALEG 358
Query: 1319 DKSALTENGEGCEAE----KQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEK-------- 1176
+ +AL +AE K+V +LE + + + +R MAEK
Sbjct: 359 ENAALAALLAAKKAEMVEASDAAGKSVRELESRLSAA--VSEASHERAMAEKLISTTRGA 416
Query: 1175 --QALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASNLTHNDEL-HKEKDDKKS--IMN 1011
+E+ +E A + +AE+ E N N+ L H E D S +
Sbjct: 417 LTAMVEENQKQVEQLRADHDQARATMQAELVAHREMRNARINERLSHPELCDSASPQVPP 476
Query: 1010 DLDRVKAEKQVLESK------VSDLETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGL 849
V +V+ S+ + +L T TLN +L + + EA E + + L
Sbjct: 477 PNTDVPVAPEVVRSEPFYCVTLDELNKT-GTLNEQLTRALAQREA------DNEKLTEEL 529
Query: 848 EKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIW 669
+R D E ++ + EA+ + L + ++ E I +KL +D+
Sbjct: 530 AQREADNEKLAEELVQR--------EADNEKLTEELAHREADI-------EKLTEDLAQR 574
Query: 668 LSEVTELQEDLNKESKEKQDLEKRVLELTSKLEK 567
+++ +L EDL + + + L + + + + +EK
Sbjct: 575 EADIEKLAEDLAQREADIEKLTEELAQREADIEK 608
>ref|XP_808187.1| myosin heavy chain [Trypanosoma cruzi strain CL Brener]
gi|70872338|gb|EAN86336.1| myosin heavy chain, putative
[Trypanosoma cruzi]
Length = 3543
Score = 105 bits (263), Expect = 1e-19
Identities = 121/521 (23%), Positives = 217/521 (41%), Gaps = 16/521 (3%)
Frame = -3
Query: 2081 QALESKVSVFEAAIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLN 1902
+ L +++ EA I L DEL + D + + D EA + L +A EA L
Sbjct: 2679 EKLVEELAQREADIEKLTDELAQREADNEKLAEDLAQREADNEKLAEDLAQREADIEKLT 2738
Query: 1901 DELERKKDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVS 1722
DEL +++ DN ++++ + K +E D L + ++
Sbjct: 2739 DELAQREADNEKLVEELAQREADIEKLTDELAQREADNEKLAEDLAQREADNEKLTEDLA 2798
Query: 1721 NLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEE 1542
E + L E+L + + D L +DL E + E ++ E+ + L E + E
Sbjct: 2799 QREADNEKLAEDLAQREADIEKLAEDLAQREADNEKLAEDLAQREADNEKLAEELAQREA 2858
Query: 1541 DEVLERSASNLAIMKAIRE---EELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASN 1371
D +E+ A +LA +A E EEL + + L E+ EA+ + L + + +R A N
Sbjct: 2859 D--IEKLAEDLAQREADNEKLAEELAQREADNEKLAEDLAQREADNEKLAEDLAQREADN 2916
Query: 1370 LDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDAL-QRDLD 1194
EEL + + D L E+ EA+ + + + E I L D L QR+
Sbjct: 2917 EKL-----AEELAQREADIEKLAEDLAQREADNEKLAEDLAQREADIEKLTDELAQRE-- 2969
Query: 1193 RVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIER------KLEASNLTHNDELHKEKD 1032
A+ + L + + EA N L + EA+IE+ + EA DEL + +
Sbjct: 2970 ---ADNEKLAEDLAQREADNEKLAEELAQREADIEKLAEDLAQREADIEKLTDELAQREA 3026
Query: 1031 DKKSIMNDLDRVKAEKQVLESKVSDLETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQG 852
D + + DL + +A+ + L ++ E L EL Q+ D E +E EA +
Sbjct: 3027 DNEKLAEDLAQREADNEKLTDDLAQREADNEKLVEELAQREADIEKLTDELAQREADNEK 3086
Query: 851 LEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAIS---ILTDKAKKLLKD 681
L + + EA + + + + NE + L +R ++ + ++ ++ K +
Sbjct: 3087 LAEDLAQREADNEKLVEELAQREADNEKLAEDLVRREADCHKLVAELDVIESKLNSAMSG 3146
Query: 680 INIWLS---EVTELQEDLNKESKEKQDLEKRVLELTSKLEK 567
++++ S V E+ E + + EK LE S K
Sbjct: 3147 LHVFSSGDGGVIEMLEGYMERASLVSGAEKDALERLSLSNK 3187
Score = 104 bits (260), Expect = 3e-19
Identities = 118/517 (22%), Positives = 220/517 (42%), Gaps = 10/517 (1%)
Frame = -3
Query: 2081 QALESKVSVFEAAIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLN 1902
+ L +++ EA L ++L + D + + D EA + L ++A EA L
Sbjct: 2637 EKLTDELAQREADNEKLAEDLAQREADNEKLAEDLAQREADNEKLVEELAQREADIEKLT 2696
Query: 1901 DELERKKDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVS 1722
DEL +++ DN + + + + K +E D+ L + ++
Sbjct: 2697 DELAQREADNEKLAEDLAQREADNEKLAEDLAQREADIEKLTDELAQREADNEKLVEELA 2756
Query: 1721 NLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEE 1542
E +I L +EL + + D L +DL E + E ++ E+ + L E + E
Sbjct: 2757 QREADIEKLTDELAQREADNEKLAEDLAQREADNEKLTEDLAQREADNEKLAEDLAQREA 2816
Query: 1541 DEVLERSASNLAIMKAIRE---EELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASN 1371
D +E+ A +LA +A E E+L + + L E EA+ + L + + +R A N
Sbjct: 2817 D--IEKLAEDLAQREADNEKLAEDLAQREADNEKLAEELAQREADIEKLAEDLAQREADN 2874
Query: 1370 LDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDR 1191
EEL + + D L E+ EA+ EK DL + N+ L +L +
Sbjct: 2875 EKL-----AEELAQREADNEKLAEDLAQREADN---EKLAEDLAQR-EADNEKLAEELAQ 2925
Query: 1190 VMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASNLTHNDELHKEKDDKKSIMN 1011
A+ + L + + EA N L ++ EA+IE+ DEL + + D + +
Sbjct: 2926 READIEKLAEDLAQREADNEKLAEDLAQREADIEKL--------TDELAQREADNEKLAE 2977
Query: 1010 DLDRVKAEKQVLESKVSDLETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLD 831
DL + +A+ + L +++ E L +L Q+ D E +E EA + L + +
Sbjct: 2978 DLAQREADNEKLAEELAQREADIEKLAEDLAQREADIEKLTDELAQREADNEKLAEDLAQ 3037
Query: 830 LEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKA-------KKLLKDINI 672
EA K D EA+ + L + +++ E I LTD+ +KL +D+
Sbjct: 3038 READ----NEKLTDDLAQREADNEKLVEELAQREADIEKLTDELAQREADNEKLAEDLAQ 3093
Query: 671 WLSEVTELQEDLNKESKEKQDLEKRVLELTSKLEKCI 561
++ +L E+L + + + L + ++ + K +
Sbjct: 3094 READNEKLVEELAQREADNEKLAEDLVRREADCHKLV 3130
Score = 101 bits (252), Expect = 2e-18
Identities = 114/522 (21%), Positives = 224/522 (42%), Gaps = 17/522 (3%)
Frame = -3
Query: 2081 QALESKVSVFEAAIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLN 1902
+ L +++ EA I L ++L + D + + + EA + L +A EA L
Sbjct: 2581 EKLAEELAQREADIEKLAEDLAQREADNEKLAEELAQREADIEKLAEDLAQREADIEKLT 2640
Query: 1901 DELERKKDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVS 1722
DEL +++ DN + + + + K +E D L+ ++
Sbjct: 2641 DELAQREADNEKLAEDLAQREADNEKLAEDLAQREADNEKLVEE--------------LA 2686
Query: 1721 NLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEE 1542
E +I L +EL + + D L +DL E + E ++ E+ L + + E
Sbjct: 2687 QREADIEKLTDELAQREADNEKLAEDLAQREADNEKLAEDLAQREADIEKLTDELAQREA 2746
Query: 1541 D--EVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNL 1368
D +++E A A ++ + +E ++E D + L E+ EA+ + L + + +R A N
Sbjct: 2747 DNEKLVEELAQREADIEKLTDELAQREADNEK-LAEDLAQREADNEKLTEDLAQREADNE 2805
Query: 1367 DTMDAIHE---------EELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLND 1215
+ + + E+L + + D L E+ EA+ + + + E I +
Sbjct: 2806 KLAEDLAQREADIEKLAEDLAQREADNEKLAEDLAQREADNEKLAEELAQREADI----E 2861
Query: 1214 ALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIER------KLEASNLTHND 1053
L DL + A+ + L + + EA N L ++ EA+ E+ + EA N +
Sbjct: 2862 KLAEDLAQREADNEKLAEELAQREADNEKLAEDLAQREADNEKLAEDLAQREADNEKLAE 2921
Query: 1052 ELHKEKDDKKSIMNDLDRVKAEKQVLESKVSDLETTYSTLNNELQQKMDDNEAFLNERDG 873
EL + + D + + DL + +A+ + L ++ E L +EL Q+ DNE +
Sbjct: 2922 ELAQREADIEKLAEDLAQREADNEKLAEDLAQREADIEKLTDELAQREADNEKLAEDLAQ 2981
Query: 872 LEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKK 693
EA + L + + EA DIE K +D EA+ + L +++ E +K
Sbjct: 2982 READNEKLAEELAQREA---DIE-KLAEDLAQREADIEKLTDELAQREA-------DNEK 3030
Query: 692 LLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLELTSKLEK 567
L +D+ ++ +L +DL + + + L + + + + +EK
Sbjct: 3031 LAEDLAQREADNEKLTDDLAQREADNEKLVEELAQREADIEK 3072
Score = 97.4 bits (241), Expect = 4e-17
Identities = 121/558 (21%), Positives = 232/558 (41%), Gaps = 21/558 (3%)
Frame = -3
Query: 2081 QALESKVSVFEAAIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLN 1902
+ L +++ EA I L DEL + D + + ++ EA + L +A EA L
Sbjct: 1205 EKLTDELAQREADIEKLTDELAQREADNEKLTDELAQREADNEKLAEDLAQREADNEKLA 1264
Query: 1901 DELERKKDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVS 1722
++L +++ DN + + + + K +E D L + ++
Sbjct: 1265 EDLAQREADNEKLAEDLAQREADNEKLAEDLAQREADNEKLAEELAQREADNEKLTEELA 1324
Query: 1721 NLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEE 1542
E + L E+L + + D L +DL E + E ++ E+ + L E + E
Sbjct: 1325 QREADNEKLAEDLAQREADNEKLAEDLAQREADNEKLTEELAQREADNEKLAEDLAQREA 1384
Query: 1541 D--EVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASN- 1371
D ++ E A A ++ + E+ ++E D + L E EA+ + L + + +R A N
Sbjct: 1385 DNEKLTEELAQREADIEKLAEDLAQREADNEK-LAEELAQREADNEKLAEELAQREADNE 1443
Query: 1370 -----LDTMDAIHE---EELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLND 1215
L +A +E EEL + + D L E+ EA+ EK DL N+
Sbjct: 1444 KLAEELAQREADNEKLAEELAQREADNEKLAEDLAQREADN---EKLTEDLAQREAD-NE 1499
Query: 1214 ALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIER------KLEASNLTHND 1053
L +L + A+ + L + EA N L ++ EA+ E+ + EA N +
Sbjct: 1500 KLAEELAQREADNEKLAEELVQREADNEKLAEDLAQREADNEKLAEDLAQREADNEKLAE 1559
Query: 1052 ELHKEKDDKKSIMNDLDRVKAEKQVLESKVSDLETTYSTLNNELQQKMDDNEAFLNERDG 873
EL + + D + + +L + +A+ + L +++ E L +L Q+ DNE E
Sbjct: 1560 ELAQREADNEKLTEELAQREADNEKLTEELAQREADNEKLAEDLAQREADNEKLAEELAQ 1619
Query: 872 LEAVKQGLE----KRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTD 705
EAV +G E K + + + ++E + + + L++ +++ + L
Sbjct: 1620 REAVIEGAEADASKTIEGVYSRCRELEELAARRELAATGDVDILERELADALVQLKALEG 1679
Query: 704 KAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLELTSKLEKCICGARDGLSTIKE 525
+ L + ++ E+ E + + ++LE R+ S+ A +ST +
Sbjct: 1680 ENAALAA---LLAAKKAEMVEASDAAGRSVRELESRLSAAVSEASHERAMAEKLISTTRG 1736
Query: 524 AWMSDCMVPDNWVPFEDL 471
A + MV +N E L
Sbjct: 1737 ALTA--MVEENQKQVEQL 1752
Score = 92.0 bits (227), Expect = 2e-15
Identities = 118/543 (21%), Positives = 224/543 (41%), Gaps = 21/543 (3%)
Frame = -3
Query: 2036 TLNDELLN-----EKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDN 1872
TLN++L E D++K + D EA + L +A EA L ++L +++ DN
Sbjct: 92 TLNEQLTRALAQREADNEK-LAEDLAQREADNEKLAEDLAQREADNEKLAEDLAQREADN 150
Query: 1871 NAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILH 1692
+ + + + K +E D+ L + ++ E + L
Sbjct: 151 EKLAEDLAQREADNEKLAEELAQREADIEKLTDELAQREADNEKLAEDLAQREADNEKLA 210
Query: 1691 EELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEED------EVL 1530
E+L + + D L +DL E + E ++ E+ + L E + E D E+
Sbjct: 211 EDLAQREADNEKLAEDLAQREADNEKLAEDLAQREADNEKLAEDLAQREADNEKLTDELA 270
Query: 1529 ERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAI 1350
+R A N + + + + E EK L E EA+ + L + +R A N
Sbjct: 271 QREADNEKLAEDLAQREADNEK-----LAEELAQREADNEKLTDELAQREADNEKLA--- 322
Query: 1349 HEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQA 1170
E+L + + D LTE+ EA+ EK DL N+ L +L + A+ +
Sbjct: 323 --EDLAQREADNEKLTEDLAQREADN---EKLAEDLAQREAD-NEKLTDELAQREADNEK 376
Query: 1169 LEKRCSDLEAKNASLTDNQEGHEAEIER------KLEASNLTHNDELHKEKDDKKSIMND 1008
L + + EA N LT++ EA+ E+ + EA N ++L + + D + ++ +
Sbjct: 377 LAEDLAQREADNEKLTEDLAQREADNEKLAEELAQREADNEKLAEDLAQREADNEKLVEE 436
Query: 1007 LDRVKAEKQVLESKVSDLETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLE----KR 840
L + +A+ + L +++ E L +L Q+ DNE E EAV +G E K
Sbjct: 437 LAQREADNEKLAEELAQREADNEKLAEDLAQREADNEKLAEELAQREAVIEGAEADASKT 496
Query: 839 VLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSE 660
+ + + ++E + + + L++ +++ + L + L + ++
Sbjct: 497 IEGVYSRCRELEELAARRELAATGDVDILERELADALVQLKALEGENAALAA---LLAAK 553
Query: 659 VTELQEDLNKESKEKQDLEKRVLELTSKLEKCICGARDGLSTIKEAWMSDCMVPDNWVPF 480
E+ E + + ++LE R+ S+ A +ST + A + MV +N
Sbjct: 554 KAEMVEASDAAGRSVRELESRLSAAVSEASHERAMAEKLISTTRGALTA--MVEENQKQV 611
Query: 479 EDL 471
E L
Sbjct: 612 EQL 614
Score = 89.7 bits (221), Expect = 9e-15
Identities = 112/535 (20%), Positives = 219/535 (40%), Gaps = 8/535 (1%)
Frame = -3
Query: 2051 EAAIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDN 1872
EA L ++L + D + + D EA + L +A EA L ++L +++ DN
Sbjct: 1840 EADNEKLAEDLAQREADNEKLAEDLAQREADNEKLAEDLAQREADNEKLAEDLAQREADN 1899
Query: 1871 NAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILH 1692
+ + + + K +E D L + ++ E + L
Sbjct: 1900 EKLAEDLAQREADNEKLAEDLAQREADNEKLAEDLAQREADNEKLVEELAQREADNEKLA 1959
Query: 1691 EELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASN 1512
E+L + + D L+++L E + + ++ E+ + L E + E D E+ A +
Sbjct: 1960 EDLAQREADNEKLVEELAQREADNEKLTDELAQREADNEKLAEDLAQREADN--EKLAED 2017
Query: 1511 LAIMKAIRE---EELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHEE 1341
LA +A E E+L + + L E+ EA+ + L + + +R A N E
Sbjct: 2018 LAQREADNEKLAEDLAQREADNEKLAEDLAQREADNEKLAEDLAQREADNEKLA-----E 2072
Query: 1340 ELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDAL-QRDLDRVMAEKQALE 1164
L + + D L E+ EA+ + + + E I L D L QR+ A+ + L
Sbjct: 2073 NLAQREADNEKLAEDLAQREADNEKLAENLAQREADIEKLTDELAQRE-----ADNEKLA 2127
Query: 1163 KRCSDLEAKNASLTDNQEGHEAEIERKLEASNLTHNDELHKEKDDKKSIMNDLDRVKAEK 984
+ + EA N L ++ EA+ E+ +E EL + + D + + ++L + +A+
Sbjct: 2128 EDLAQREADNEKLAEDLAQREADNEKLVE--------ELAQREADNEKLTDELAQREADN 2179
Query: 983 QVLESKVSDLETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLE----KRVLDLEATI 816
+ L ++ E L +L Q+ DNE E EAV +G E K + + +
Sbjct: 2180 EKLAEDLAQREADNEKLAEDLAQREADNEKLAEELAQREAVIEGAEADASKTIEGVYSRC 2239
Query: 815 HDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDL 636
++E + + + L++ +++ + L + L + ++ E+ E
Sbjct: 2240 RELEELAARRELAATGDVDILERELADALVQLKALEGENAALAA---LLAAKKAEMVEAS 2296
Query: 635 NKESKEKQDLEKRVLELTSKLEKCICGARDGLSTIKEAWMSDCMVPDNWVPFEDL 471
+ + ++LE R+ S+ A +ST + A + MV +N E L
Sbjct: 2297 DAAGRSVRELESRLSAAVSEASHERAMAEKLISTTRGALTA--MVEENQKQVEQL 2349
Score = 76.3 bits (186), Expect = 1e-10
Identities = 95/419 (22%), Positives = 173/419 (41%), Gaps = 10/419 (2%)
Frame = -3
Query: 1697 LHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEED------E 1536
L E+L + + D L +DL E + E ++ E+ + L E + E D E
Sbjct: 708 LAEDLAQREADNEKLAEDLAQREADNEKLAEDLAQREADNEKLAEELAQREADIEKLTDE 767
Query: 1535 VLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMD 1356
+ +R A N + + + + E EK LVE EA+ + L + +R A N
Sbjct: 768 LAQREADNEKLAEDLAQREADNEK-----LVEELAQREADIEKLTDELAQREADNEKLA- 821
Query: 1355 AIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEK 1176
EEL + + D LT+ EA+ EK DL N+ L DL + A+
Sbjct: 822 ----EELAQREADIEKLTDELAQREADN---EKLAEDLAQREAD-NEKLAEDLAQREADN 873
Query: 1175 QALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASNLTHNDELHKEKDDKKSIMNDLDRV 996
+ L + + EA N L ++ EA+ E+ E +L + + D + + DL +
Sbjct: 874 EKLAEDLAQREADNEKLAEDLAQREADNEKLAE--------DLAQREADNEKLAEDLAQR 925
Query: 995 KAEKQVLESKVSDLETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLE----KRVLDL 828
+A+ + L +++ E L +L Q+ DNE E EAV +G E K + +
Sbjct: 926 EADNEKLTDELAQREADNEKLAEDLAQREADNEKLAEELAQREAVIEGAEADASKTIEGV 985
Query: 827 EATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTEL 648
+ ++E + + + L++ +++ + L + L + ++ E+
Sbjct: 986 YSRCRELEELAARRELAATGDVDILERELADALVQLKALEGENAALAA---LLAAKKAEM 1042
Query: 647 QEDLNKESKEKQDLEKRVLELTSKLEKCICGARDGLSTIKEAWMSDCMVPDNWVPFEDL 471
E + + ++LE R+ S+ A +ST + A + MV +N E L
Sbjct: 1043 VEASDAAGRSVRELESRLSAAVSEASHERAMAEKLISTTRGALTA--MVEENQKQVEQL 1099
Score = 73.2 bits (178), Expect = 9e-10
Identities = 120/560 (21%), Positives = 218/560 (38%), Gaps = 55/560 (9%)
Frame = -3
Query: 2081 QALESKVSVFEAAIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLN 1902
+ L +++ EA I L DEL + D + + D EA + L ++A EA L
Sbjct: 748 EKLAEELAQREADIEKLTDELAQREADNEKLAEDLAQREADNEKLVEELAQREADIEKLT 807
Query: 1901 DELERKKDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVS 1722
DEL +++ DN + ++ + K +E D L + ++
Sbjct: 808 DELAQREADNEKLAEELAQREADIEKLTDELAQREADNEKLAEDLAQREADNEKLAEDLA 867
Query: 1721 NLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREE- 1545
E + L E+L + + D L +DL E + E ++ E+ + L E + E
Sbjct: 868 QREADNEKLAEDLAQREADNEKLAEDLAQREADNEKLAEDLAQREADNEKLAEDLAQREA 927
Query: 1544 -----EDEVLERSASN--LAIMKAIRE---EELRKEKDGKSALVENG--------EGCEA 1419
DE+ +R A N LA A RE E+L +E + A++E EG +
Sbjct: 928 DNEKLTDELAQREADNEKLAEDLAQREADNEKLAEELAQREAVIEGAEADASKTIEGVYS 987
Query: 1418 EKQGLEKTVLERRASNLDTMDAIHEE------ELRKEKVDKSAL-----TENGEGCEAEK 1272
+ LE+ R + +D + E +L+ + + +AL + E EA
Sbjct: 988 RCRELEELAARRELAATGDVDILERELADALVQLKALEGENAALAALLAAKKAEMVEA-S 1046
Query: 1271 QGPEKTVLDLEPTIPSLNDALQRDLDRVMAEK----------QALEKRCSDLEAKNASLT 1122
++V +LE + + + +R MAEK +E+ +E A
Sbjct: 1047 DAAGRSVRELESRLSAA--VSEASHERAMAEKLISTTRGALTAMVEENQKQVEQLRADHD 1104
Query: 1121 DNQEGHEAEIERKLEASNLTHNDEL-HKEKDDKKS-----------IMNDLDRVKAEKQV 978
+ +AE+ E N N+ L H E D S + ++ R + V
Sbjct: 1105 QARATMQAELVAHREMRNARINERLSHPELCDSASPQMPPPNTEVPVAPEIVRSEPLYSV 1164
Query: 977 LESKVSDLETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMK 798
+++ T L L Q+ DNE + EA + L + EA I + +
Sbjct: 1165 TIDELNKTTTLNEQLTRALAQREADNEKLAEDLAQREADIEKLTDELAQREADIEKLTDE 1224
Query: 797 TGKDDDYNEAEKQTLKKRISELEEAISILTDKA---KKLLKDINIWLSEVTELQEDLNKE 627
+ + NE L +R ++ E+ L + +KL +D+ ++ +L EDL +
Sbjct: 1225 LAQREADNEKLTDELAQREADNEKLAEDLAQREADNEKLAEDLAQREADNEKLAEDLAQR 1284
Query: 626 SKEKQDLEKRVLELTSKLEK 567
+ + L + + + + EK
Sbjct: 1285 EADNEKLAEDLAQREADNEK 1304
Score = 72.8 bits (177), Expect = 1e-09
Identities = 117/571 (20%), Positives = 216/571 (37%), Gaps = 78/571 (13%)
Frame = -3
Query: 2051 EAAIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDN 1872
EA L DEL + D + + D EA + L ++A EA L DEL +++ DN
Sbjct: 259 EADNEKLTDELAQREADNEKLAEDLAQREADNEKLAEELAQREADNEKLTDELAQREADN 318
Query: 1871 NAIIKKALDKRISD--LKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILI 1698
+ + + + L D QR+ +++ A + ++ E +
Sbjct: 319 EKLAEDLAQREADNEKLTEDLAQREADNEKLA----------------EDLAQREADNEK 362
Query: 1697 LHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSA 1518
L +EL + + D L +DL E + E ++ E+ + L E + E D E+ A
Sbjct: 363 LTDELAQREADNEKLAEDLAQREADNEKLTEDLAQREADNEKLAEELAQREADN--EKLA 420
Query: 1517 SNLAIMKAIRE---EELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIH 1347
+LA +A E EEL + + L E EA+ + L + + +R A N + +
Sbjct: 421 EDLAQREADNEKLVEELAQREADNEKLAEELAQREADNEKLAEDLAQREADNEKLAEELA 480
Query: 1346 EEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQAL 1167
+ E E + A ++ EG + + E+ E D L+R+L + + +AL
Sbjct: 481 QREAVIEGAEADA-SKTIEGVYSRCRELEELAARRELAATGDVDILERELADALVQLKAL 539
Query: 1166 E------------KRCSDLEAKNA------------SLTDNQEGHEAEIERKLEAS---- 1071
E K+ +EA +A S ++ HE + KL ++
Sbjct: 540 EGENAALAALLAAKKAEMVEASDAAGRSVRELESRLSAAVSEASHERAMAEKLISTTRGA 599
Query: 1070 -------NLTHNDELHKEKDDKKSIM-------NDLDRVKAEKQVLESKVSD-------- 957
N ++L + D ++ M ++ + +++ ++ D
Sbjct: 600 LTAMVEENQKQVEQLRADHDQARATMQAELVAHREMRNARINERLSHPELCDSASPQMPP 659
Query: 956 -------------LETTYSTLNNELQQKMDDNE----AFLNERDGLEAVKQGLEKRVLDL 828
E YS +EL + NE A E + + L +R D
Sbjct: 660 PNTEVPVAPEIVRSEPLYSVTIDELNKTTTLNEQLTRALAQREADNEKLAEDLAQREADN 719
Query: 827 EATIHDIEM------KTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWL 666
E D+ K +D EA+ + L + +++ E I LTD+ + D
Sbjct: 720 EKLAEDLAQREADNEKLAEDLAQREADNEKLAEELAQREADIEKLTDELAQREADNEKLA 779
Query: 665 SEVTELQEDLNKESKEKQDLEKRVLELTSKL 573
++ + + D K +E E + +LT +L
Sbjct: 780 EDLAQREADNEKLVEELAQREADIEKLTDEL 810
Score = 68.6 bits (166), Expect = 2e-08
Identities = 109/544 (20%), Positives = 210/544 (38%), Gaps = 41/544 (7%)
Frame = -3
Query: 2081 QALESKVSVFEAAIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLN 1902
+ L +++ EA L ++L + D + + D EA + L +A EA L
Sbjct: 305 EKLTDELAQREADNEKLAEDLAQREADNEKLTEDLAQREADNEKLAEDLAQREADNEKLT 364
Query: 1901 DELERKKDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVS 1722
DEL +++ DN + + + + K +E D L + ++
Sbjct: 365 DELAQREADNEKLAEDLAQREADNEKLTEDLAQREADNEKLAEELAQREADNEKLAEDLA 424
Query: 1721 NLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREE- 1545
E + L EEL + + D L ++L E + E ++ E+ + L E + E
Sbjct: 425 QREADNEKLVEELAQREADNEKLAEELAQREADNEKLAEDLAQREADNEKLAEELAQREA 484
Query: 1544 --EDEVLERSASNLAIMKAIRE-EELRK-------------EKDGKSALVENGEGCEAEK 1413
E + S + + RE EEL E++ ALV+ + E E
Sbjct: 485 VIEGAEADASKTIEGVYSRCRELEELAARRELAATGDVDILERELADALVQL-KALEGEN 543
Query: 1412 QGLEKTVLERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPT 1233
L + ++A ++ DA E +A++E E+ EK +
Sbjct: 544 AALAALLAAKKAEMVEASDAAGRSVRELESRLSAAVSE----ASHERAMAEKLISTTRGA 599
Query: 1232 IPSLNDALQRDLDRVMAE-KQALEKRCSDL----EAKNASLTDNQEGHE----------- 1101
+ ++ + Q+ ++++ A+ QA ++L E +NA + + E
Sbjct: 600 LTAMVEENQKQVEQLRADHDQARATMQAELVAHREMRNARINERLSHPELCDSASPQMPP 659
Query: 1100 --------AEIERKLEASNLTHNDELHKEKDDKKSIMNDLDRVKAEKQVLESKVSDLETT 945
EI R ++T DEL+K + + L + +A+ + L ++ E
Sbjct: 660 PNTEVPVAPEIVRSEPLYSVT-IDELNKTTTLNEQLTRALAQREADNEKLAEDLAQREAD 718
Query: 944 YSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAE 765
L +L Q+ DNE + EA + L + + EA I + + + + NE
Sbjct: 719 NEKLAEDLAQREADNEKLAEDLAQREADNEKLAEELAQREADIEKLTDELAQREADNEKL 778
Query: 764 KQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLEL 585
+ L +R ++ E+ + L + DI E+ + + D K ++E E + +L
Sbjct: 779 AEDLAQREADNEKLVEELAQRE----ADIEKLTDELAQREADNEKLAEELAQREADIEKL 834
Query: 584 TSKL 573
T +L
Sbjct: 835 TDEL 838
>ref|XP_001582797.1| viral A-type inclusion protein [Trichomonas vaginalis G3]
gi|121917034|gb|EAY21811.1| viral A-type inclusion
protein, putative [Trichomonas vaginalis G3]
Length = 1553
Score = 105 bits (262), Expect = 2e-19
Identities = 110/486 (22%), Positives = 216/486 (44%), Gaps = 23/486 (4%)
Frame = -3
Query: 1955 QALEYKVADLEAAKTTLNDEL---ERKKDDNNAIIK------KALDKRISDLKADAPQRD 1803
++L+ + A+L+A L D+L ++D N+IIK KAL DL A Q
Sbjct: 117 ESLKKENANLKARIKELEDQLALLNTERDGYNSIIKDKDNQFKALQAERDDLAAKINQLT 176
Query: 1802 QEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDKTALIKDL------ 1641
Q+ +N S + N + +++ DDKT+ DL
Sbjct: 177 QKCQLNDAEKNALQAKLDSSENSLNESRNQCNFI------KQQLDDKTSQCNDLGTKLSQ 230
Query: 1640 ---VAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNLAIMKAIREEELRK 1470
AE + +N++ + +++KS+ +K++ EDE+ + + +MK +EE +
Sbjct: 231 ADQTIAEKIE-AINQLNNEIDNKSKIIKQY-----EDELAKSKEDSEELMKKYQEETDKL 284
Query: 1469 EKDGKSALVE-NGEGCEAEKQGLEKTVLERRASNLDTMDAIHEEELRKEKVDKSALTENG 1293
+KD ++ E + AE +K L+ L ++ E++++ + DKS L
Sbjct: 285 KKDSENLQNELQNQKSLAELNASDKGNLQSAVKQLQDDNSNLEKQIKVLQDDKSNLEIQR 344
Query: 1292 EGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQ 1113
E E E + +K+ + + + L + ++ E L+K+ DL + +N
Sbjct: 345 EKLEQEVEELKKSQQENDEKYQKEKEDLTQTVNNQNNEISNLKKQNEDLSNSTTNEINNL 404
Query: 1112 EGHEAEIERK---LEASNLTHNDELHKEKDDKKSIMNDLDRVKAEKQVLESKVSDLETTY 942
+++ + LE N +N+ + D+ ++ ++ EK L+ + +L T
Sbjct: 405 NKQIQDLQNQKSDLEKQNADYNNTVSNNNDELANLKKLNQELQNEKSNLQKETENLSNTV 464
Query: 941 STLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEK 762
+ NNE+++ NE NE+ L+ VK+ L + + I D++ K ++ + +
Sbjct: 465 NDKNNEIEELKKQNEDLQNEKQNLQKVKEDLTNTITTKDDEIKDLK----KQNEDLQNQN 520
Query: 761 QTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQ-EDLNKESKEKQDLEKRVLEL 585
L+K+ +L ++ D LK+ N L E + Q +D+N K QDLE +V +L
Sbjct: 521 NDLEKQKEDLNNTVA-NKDSELNNLKNDNQQLQEANKKQNDDINNLKKSNQDLEDKVTDL 579
Query: 584 TSKLEK 567
K+++
Sbjct: 580 EGKIDE 585
Score = 90.1 bits (222), Expect = 7e-15
Identities = 123/618 (19%), Positives = 242/618 (39%), Gaps = 129/618 (20%)
Frame = -3
Query: 2042 IATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLND------ELERKK 1881
I T +DE+ + K + + N N LE K+ L VA+ ++ L + E +K+
Sbjct: 499 ITTKDDEIKDLKKQNEDLQNQNNDLEKQKEDLNNTVANKDSELNNLKNDNQQLQEANKKQ 558
Query: 1880 DDNNAIIKKA---LDKRISDL--KADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNL 1716
+D+ +KK+ L+ +++DL K D + E M + + V L
Sbjct: 559 NDDINNLKKSNQDLEDKVTDLEGKIDEMTAENEGLMENVKTRDLQLDNLQGEHSQTVDEL 618
Query: 1715 EVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLES-----KSRSLKEHFLR 1551
N L L ++ D L + E K + + V LE K+ SL
Sbjct: 619 NQNNLSLQMQIDSLNSDVNDLKSQKDSLEKDKSDLEKKVKELEEALEDEKNSSLLNSSNF 678
Query: 1550 EEEDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASN 1371
EE + L + L + + ++K ++ K+ L +N + ++K + +AS
Sbjct: 679 NEESQKLMDKINELTKQNREKNQNIKKLENEKANLQQNNDNLNQRLDNVKKQYEDLQASK 738
Query: 1370 LDTMDAIHE--EELRKEKVDKSALTENGEGCEA--------------------------- 1278
+ + ++ E+ KE+ + L++ + +
Sbjct: 739 SELVGKYNDLVEKFNKERQTNNELSQQNQAQKQQIQQLMNDLASLRDGKSDIVQKYNDLV 798
Query: 1277 -----EKQGPEKTVLDLEPTIPSLNDALQR-----------------DLDRVMAEKQALE 1164
E+Q KT DL+ I L DAL + DL++ + ++LE
Sbjct: 799 AKFNDERQEAAKTKSDLQNQIQQLKDALAKAESNQKETQNKLDISNSDLEKEKDKSKSLE 858
Query: 1163 KRCSDLEAKNASLTDNQEGHEAEIERKLE---ASNLTHNDELHKEKDDKKSIMN------ 1011
+ + L++K + + + E+++E + + +SN +D+L K + + + ++N
Sbjct: 859 EELAALKSKLQQVQEEKANLESDLENERQNNSSSNAELSDKLSKLQQENRDLVNQINQLQ 918
Query: 1010 ---------------DLDRVKAEKQVLESKVSDLETTYSTLNNELQQKMDDNEA------ 894
DLD + Q LES+++D++ L+ +L +DDNE
Sbjct: 919 NDLKQKESEIQKVSSDLDNLNNVIQDLESQMNDMQGKNDELSKKLSNLVDDNERKDKLID 978
Query: 893 --------FLNERDGLEAVKQGLEKRVLDLE-------ATIHDIEMKTGKDDDYNEA--- 768
NE+D L E LDL I D++ ++ D N +
Sbjct: 979 DLNSQLSNLNNEKDSLTNKLSETESEKLDLANQNEKLLKVIEDLQRSLSEEKDKNNSSLL 1038
Query: 767 -------EKQTLKKRISELEEAISIL-------TDKAKKLLKDINIWLSEVTELQEDLNK 630
E LK+++++LE+ +S L ++ KL D+ + ++++ K
Sbjct: 1039 SLGDFGKENALLKEKVADLEKQVSNLKQENETQNEEISKLNNDLREAADYIEKIKQQYLK 1098
Query: 629 ESKEKQDLEKRVLELTSK 576
KE Q L++ + +L ++
Sbjct: 1099 LKKENQALKEEISKLKAE 1116
Score = 74.7 bits (182), Expect = 3e-10
Identities = 112/523 (21%), Positives = 209/523 (39%), Gaps = 37/523 (7%)
Frame = -3
Query: 2033 LNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKK 1854
L +EL N+K + +D+ L++A + L+ ++LE L D+ N I ++
Sbjct: 291 LQNELQNQKSLAELNASDKGNLQSAVKQLQDDNSNLEKQIKVLQDD-----KSNLEIQRE 345
Query: 1853 ALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKE 1674
L++ + +LK + QE+D E+ QKE
Sbjct: 346 KLEQEVEELK----KSQQEND---------------------------------EKYQKE 368
Query: 1673 KDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLRE-----EEDEVLERSASNL 1509
K+D T + + N +S+L+ ++ L E ++ + L+ S+L
Sbjct: 369 KEDLTQTVNNQ----------NNEISNLKKQNEDLSNSTTNEINNLNKQIQDLQNQKSDL 418
Query: 1508 AIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHEEELRK 1329
A + D + L + + + EK L+K + D + I EEL+K
Sbjct: 419 EKQNADYNNTVSNNNDELANLKKLNQELQNEKSNLQKETENLSNTVNDKNNEI--EELKK 476
Query: 1328 EKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSD 1149
+ D + EKQ +K DL TI + +D + +DL + + + L+ + +D
Sbjct: 477 QNED----------LQNEKQNLQKVKEDLTNTITTKDDEI-KDLKK---QNEDLQNQNND 522
Query: 1148 LEAKNASLTDNQEGHEAEIE------RKLEASNLTHNDELH---KEKDDKKSIMNDL--- 1005
LE + L + ++E+ ++L+ +N ND+++ K D + + DL
Sbjct: 523 LEKQKEDLNNTVANKDSELNNLKNDNQQLQEANKKQNDDINNLKKSNQDLEDKVTDLEGK 582
Query: 1004 -DRVKAEKQVLESKVSDLETTYSTLNNELQQKMDDN-----------EAFLNERDGLEAV 861
D + AE + L V + L E Q +D+ ++ ++ + L++
Sbjct: 583 IDEMTAENEGLMENVKTRDLQLDNLQGEHSQTVDELNQNNLSLQMQIDSLNSDVNDLKSQ 642
Query: 860 KQGLEKRVLDLEATIHDIEMKTGKD--------DDYNEAEKQTLKKRISELEEAISILTD 705
K LEK DLE + ++E + ++NE E Q L +I+EL +
Sbjct: 643 KDSLEKDKSDLEKKVKELEEALEDEKNSSLLNSSNFNE-ESQKLMDKINELTKQNREKNQ 701
Query: 704 KAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLELTSK 576
KKL + L + L+ K+ +DL+ EL K
Sbjct: 702 NIKKLENEKANLQQNNDNLNQRLDNVKKQYEDLQASKSELVGK 744
Score = 70.5 bits (171), Expect = 6e-09
Identities = 116/538 (21%), Positives = 216/538 (40%), Gaps = 49/538 (9%)
Frame = -3
Query: 2042 IATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAI 1863
I L ++L ++ + + + +D + L Q LE ++ D++ L+ +L DDN
Sbjct: 914 INQLQNDLKQKESEIQKVSSDLDNLNNVIQDLESQMNDMQGKNDELSKKLSNLVDDN--- 970
Query: 1862 IKKALDKRISDLKADAPQRDQEDDM--NALIXXXXXXXXXXXXXXKIVSNLEVNILILHE 1689
+ DK I DL + + E D N L K++ +E L
Sbjct: 971 --ERKDKLIDDLNSQLSNLNNEKDSLTNKLSETESEKLDLANQNEKLLKVIED----LQR 1024
Query: 1688 ELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKE-------------HFLRE 1548
L +EKD + + L + E V+ LE + +LK+ + LRE
Sbjct: 1025 SLSEEKDKNNSSLLSLGDFGKENALLKEKVADLEKQVSNLKQENETQNEEISKLNNDLRE 1084
Query: 1547 EEDEVLERSASNLAIMK---AIREE--ELRKEKDGKSALVE--NGEGCEAEKQ--GLEKT 1395
D + + L + K A++EE +L+ E D ++ ++ N + + E+Q L T
Sbjct: 1085 AADYIEKIKQQYLKLKKENQALKEEISKLKAENDEHNSTIDQLNDDKRDLEEQLKELNIT 1144
Query: 1394 VLERRASNLDTMDAIHEEELRKEKVD-------KSALTENGEGCEAEKQGPEKTVLDLEP 1236
+ E ++ + + EE K+ ++ KS + +N E EAE V +
Sbjct: 1145 LDEEKSKSFSLNENASEELKNKDDINDGLKSQLKSQVQQNKE-IEAENHNLRSQVDQYK- 1202
Query: 1235 TIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEA---EIERKLEASNL 1065
S ND L+ + E L+ S E KN + + + + ++E L S
Sbjct: 1203 ---SSNDELETQISNYQEENSNLQDLLSSSENKNKDINEQNKQLKQKLQQLENSLRESEN 1259
Query: 1064 THNDELHKEKDDKKSIMNDLDRVKAEKQVLESKVSDLETTYSTLNNELQQKMDDNEAFLN 885
+N+ + D+ + L + S+ +L LNN L + N+ N
Sbjct: 1260 KYNNLVKSNCDEITKLSQQLQDAMQDNAKYSSEKDNLIKKLKELNNNLNVQKSQNKQIEN 1319
Query: 884 ERDGLEAVKQGLEKRVLDL------EATIHDI--EMKT-GKDDDYNEAEKQTLKKRISEL 732
+R LE Q L+ ++ +L I D+ +M+T ++++ + +++R+ L
Sbjct: 1320 QRSFLERENQRLKSQISELSKNQIPSVDIEDLKYQMRTLTIENEHLKKNNDEIRQRMRHL 1379
Query: 731 EEA---ISILTDKAKKLLKDIN---IWLSEVTELQEDLNKESKEKQDLEKRVLELTSK 576
E +SI ++ + L + +WLS + K KE DL + + SK
Sbjct: 1380 ESTNAQLSIQNNQNELKLCTLEQRCVWLSGAHD------KLRKENFDLSSTIDTMNSK 1431
>ref|XP_009292628.1| PREDICTED: nesprin-1 isoform X4 [Danio rerio]
Length = 15654
Score = 103 bits (256), Expect = 8e-19
Identities = 128/547 (23%), Positives = 231/547 (42%), Gaps = 48/547 (8%)
Frame = -3
Query: 2033 LNDELLNEKDDKKCIVND----RNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNA 1866
+ +EL EK+ + D + IL+ K A E +ADL+ K+ L + E
Sbjct: 4672 MTEELKKEKESFTHLAEDTKTEKKILDKMKVANESLMADLQKEKSNLEEMRENISKQTED 4731
Query: 1865 IIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEE 1686
K+ R+ + + + Q + + K V +L+ + L +
Sbjct: 4732 SEKEKEKIRLREDELEQLQAEIHKQQGEIKMEKSNNESERAAIIKDVKDLQHKMFSLDRD 4791
Query: 1685 LQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVL-------- 1530
L+ K D+ A E + + +I + L+ K+ +++ L + D
Sbjct: 4792 LESLKLDREAF-------ENEREVLKQIKTDLKRKAEEIEKIKLETQHDRQRVEEMTAQI 4844
Query: 1529 --ERSASNLAIMKAIREEELRKE-----KDGKSALVENGEGCEAEKQGLEKT--VLERRA 1377
ER N I + R++ + E K+ A+ + + E EK LEKT L R
Sbjct: 4845 QKERDKINNLIEETNRKDMVLNEIKTEIKEKIKAIESDRDMLEKEKHDLEKTRSKLLRAK 4904
Query: 1376 SNLDTMDAIHEEELRKEKVDKSALTE------NGEGCEAEKQGPEKTVLD-LEPTIPSLN 1218
NL+ I E++KE+ D + E + + E+ ++ LD L+ I +L
Sbjct: 4905 ENLEKQRKIKLAEIQKEREDLEKMNEKFTIEIHDIKHQEEQMKQKQDELDQLKTEIQNLQ 4964
Query: 1217 DALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIER--KLEASNLTHNDELH 1044
L+++ + +M ++ L+ R S+L+ + ++ D E + E ++ K + E+
Sbjct: 4965 QELEKEKEIIMKDRSQLDLRQSELDKQQTNVNDIMETMKNERKQLDKDKEETEEQKQEME 5024
Query: 1043 KEKDD----KKSIMNDLDRVKAEKQVLESKVSDLETTYSTLNNELQQKMDDNEAFLNERD 876
KEK D +KS+ DL +K +KQVLE + S LE L E + E NER
Sbjct: 5025 KEKHDFDQSRKSLDEDLKMMKLQKQVLEDEKSKLEQMKIELEREAVEIRKIKEEIQNERQ 5084
Query: 875 GLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTL------KKRISELEEAISI 714
LE + + L++ DL + + D+ A + TL K + E+ E IS
Sbjct: 5085 NLEKMTEALKEEREDL---AEETKKNNQVLDEMKVANESTLADILREKSNLEEMRENISK 5141
Query: 713 LTDKAKKLLKDINIWLSEVTELQEDLNKE----SKEKQDLEKRVLELTSKLE----KCIC 558
T+ + +++ + E+ +LQ +++K+ KEK ++E + +E K IC
Sbjct: 5142 QTEDVENKKENLRLREDELRQLQAEIHKQQREIEKEKINIESERAAIIKDVEDLQHKIIC 5201
Query: 557 GARDGLS 537
RD S
Sbjct: 5202 LDRDAES 5208
Score = 100 bits (248), Expect = 7e-18
Identities = 131/576 (22%), Positives = 258/576 (44%), Gaps = 33/576 (5%)
Frame = -3
Query: 2027 DELLNEKDDK-----KCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAI 1863
D +LNEK+ K I +D+++LE K LE ++L K ++LE++K++ A
Sbjct: 6149 DMVLNEKNRDIEKKIKSIQSDKDMLEKEKHDLEKTRSELYKVK----EDLEKQKENTLAQ 6204
Query: 1862 IKKA---LDKRISDLKADAPQ-RDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILIL 1695
I+K L+K ++ + + + QE+ MN + L+ I L
Sbjct: 6205 IQKEREDLEKMNENITREMHEIKHQEEQMNQ--------------KQDELDQLKTEIQNL 6250
Query: 1694 HEELQKEKD----DKTALIKDLVAAEPGKRTVNEIVSHLESKSRSL-KEHFLREEEDEVL 1530
+EL+KEK+ ++ L + + + +N+I+ ++++ + L K+ EE+ + +
Sbjct: 6251 QQELEKEKEIIMKARSQLDRRQSELDKQQTNMNDIMETMKNERKQLDKDKEEMEEQKQEM 6310
Query: 1529 ERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAI 1350
E+ N+ + +E+L+ K K + E E K LE+ + R +T +
Sbjct: 6311 EKERDNMDQSRKSLDEDLKMMKLQKQVIEEEKNKLEQMKIELEREADDIRKIKEETQNKR 6370
Query: 1349 H-----EEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVM 1185
EEL+KE+ D + L E+ + EK ++ + E ++ L Q++ +
Sbjct: 6371 QILEKMAEELKKERKDVAHLAED---TKREKNSLDEMKVANESSMADL----QKEKSNLE 6423
Query: 1184 AEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASNLTHNDELHKEKDDKKSIMNDL 1005
K+ + K+ D+E + D E E+E+ L+A E+HK++ + + +++
Sbjct: 6424 EMKENISKQTEDIEKEK----DKIRLREDELEQ-LQA-------EIHKQQSETEIEKSNI 6471
Query: 1004 DRVKAEKQVLESKVSDLETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLE 825
+R E+ + V DL++ +L+ + + D EAF NE++ L+ +K LE+ ++E
Sbjct: 6472 ER---ERAAIIKDVEDLQSKIISLDRDAESLKLDREAFENEKEELKQMKTELEREADEIE 6528
Query: 824 ----ATIHD----IEMKTGKDDDYNEAEKQTLKKRI------SELEEAISILTDKAKKLL 687
T H+ EM + N KQ K ++ E+E+ + K L
Sbjct: 6529 KIKLETQHERQRVEEMTADFMETMNNERKQLDKNKVMIEEQKQEMEKKRDDMDQSRKSLD 6588
Query: 686 KDINIWLSEVTELQEDLNKESKEKQDLEKRVLELTSKLEKCICGARDGLSTIKEAWMSDC 507
+D+ + ++ L+E+ NK + K LE+ E+ SK+++ R L + A +
Sbjct: 6589 EDLKMMKAQKQVLEEEKNKLEQMKIGLEREADEI-SKIKEETQNERQNLEKMANALKEE- 6646
Query: 506 MVPDNWVPFEDLVQGFSRKTSPLDITKTCDAVDISE 399
E L + RK LD K + +++
Sbjct: 6647 --------REYLAEEIKRKNQVLDKIKVANESTLAD 6674
Score = 97.8 bits (242), Expect = 3e-17
Identities = 120/531 (22%), Positives = 231/531 (43%), Gaps = 36/531 (6%)
Frame = -3
Query: 2072 ESKVSVFEAAIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDEL 1893
E KV + E+A+A + E N + ++ + ++++ K+ + + L+ + +N +
Sbjct: 3534 EMKV-LHESALADIQKEKCNLEQMRESMFKQNEMIDSEKKKMILREDKLQQMQAEINRQ- 3591
Query: 1892 ERKKDDNNAIIKK---ALDKRISDLKADAPQR--DQEDDMNALIXXXXXXXXXXXXXXKI 1728
+ + D +II+ A+ K+ DL + ++ D E M ++ K
Sbjct: 3592 QTEMDTKKSIIENERAAMTKKNQDLMTELTKQSEDVEIQMKEVLTEKELLESDRKLLKKD 3651
Query: 1727 VSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLRE 1548
V NL+ +LI+ + + K D+ L + + K + +E + R
Sbjct: 3652 VENLQQKLLIIESDSESLKQDRELLENEKEVLKQMKTDLQGEAEEIEKIKLETQHERQRV 3711
Query: 1547 EEDEVL---ERSASNLAIMKAIREEELRKEKDGK-----SALVENGEGCEAEKQGLEKTV 1392
EE ER N I + R++ + EK+ ++ + + E EK LEKT
Sbjct: 3712 EEMTAQIQKERDKINNLIEETNRKDMVLNEKNRDIEEKIKSIQSDKDMLEKEKHNLEKTR 3771
Query: 1391 ---------LERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKT--VLD 1245
LE++ N T+ I +E EK++++ E E E+Q +K +
Sbjct: 3772 SELYKVKEDLEKQKEN--TLAEIQKEREDLEKMNENITIEMHEIKHQEEQMKQKQDELDQ 3829
Query: 1244 LEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEG--HEAEIERKLEAS 1071
L+ I +L L+++ + +M ++ L+ R S+L+ + ++ D E +E ++ K +
Sbjct: 3830 LKTEIQNLQQELEKEKEIIMKDRSELDLRQSELDKQQTNMNDIIETMKNERKLLDKDKEE 3889
Query: 1070 NLTHNDELHKEKDDK----KSIMNDLDRVKAEKQVLESKVSDLETTYSTLNNELQQKMDD 903
E+ KE+D+ KS+ DL +K +KQV+E + + LE L E +
Sbjct: 3890 MEEQKQEMEKERDNMDQSIKSLDEDLKMMKLQKQVIEEEKNKLEQMKFELQREADEIRKI 3949
Query: 902 NEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTL------KKRI 741
E NER LE + + L K DL + + D+ A K ++ K+ +
Sbjct: 3950 KEETQNERQSLEKMTKALIKEREDLVHLAEYTKREKEMLDEMQVANKSSMADLQREKRIL 4009
Query: 740 SELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLE 588
E+ E IS T+ + + + E+ +LQ ++ K+ E D+EK +E
Sbjct: 4010 EEMRENISKQTEDIENEKEKSKLREDELKKLQTEVQKQQSE-IDMEKTNIE 4059
Score = 97.1 bits (240), Expect = 6e-17
Identities = 130/534 (24%), Positives = 241/534 (45%), Gaps = 47/534 (8%)
Frame = -3
Query: 2027 DELLNE-----KDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLND-------ELERK 1884
D +LNE K+ K I +DR++LE K LE + L AK L E++++
Sbjct: 4862 DMVLNEIKTEIKEKIKAIESDRDMLEKEKHDLEKTRSKLLRAKENLEKQRKIKLAEIQKE 4921
Query: 1883 KDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNI 1704
++D + +K I D+K Q Q+ D + L+ I
Sbjct: 4922 REDLEKMNEK-FTIEIHDIKHQEEQMKQKQDE--------------------LDQLKTEI 4960
Query: 1703 LILHEELQKEKD----DKTALIKDLVAAEPGKR--TVNEIVSHLESKSRSL-KEHFLREE 1545
L +EL+KEK+ D++ L DL +E K+ VN+I+ ++++ + L K+ EE
Sbjct: 4961 QNLQQELEKEKEIIMKDRSQL--DLRQSELDKQQTNVNDIMETMKNERKQLDKDKEETEE 5018
Query: 1544 EDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLD 1365
+ + +E+ + + +E+L+ K K L + E K LE+ +E R
Sbjct: 5019 QKQEMEKEKHDFDQSRKSLDEDLKMMKLQKQVLEDEKSKLEQMKIELEREAVEIRKIK-- 5076
Query: 1364 TMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVM 1185
+ I E EK+ + AL E E E + + + +++ S + R+ +
Sbjct: 5077 --EEIQNERQNLEKMTE-ALKEEREDLAEETKKNNQVLDEMKVANESTLADILREKSNLE 5133
Query: 1184 AEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASNLTHNDELHKEKDDKKSIMNDL 1005
++ + K+ D+E K +N E E+ R+L+A E+HK++ + I +
Sbjct: 5134 EMRENISKQTEDVENKK----ENLRLREDEL-RQLQA-------EIHKQQ---REIEKEK 5178
Query: 1004 DRVKAEKQVLESKVSDLETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLE 825
+++E+ + V DL+ L+ + + D EAF NE++ L+ +K LE+ ++E
Sbjct: 5179 INIESERAAIIKDVEDLQHKIICLDRDAESLKLDREAFENEKEVLKQMKTELEREADEIE 5238
Query: 824 ----ATIHD--------IEMKTGKDDDYNEAEK-----QTLKKRISELEEAI-SILTDK- 702
T HD +++ +D+ N E+ L ++ ++EE I SI +DK
Sbjct: 5239 KIKLETQHDRQRVEEMAAQIQKDRDEINNLIEETNRKDMVLNEKNRDIEEKIKSIQSDKD 5298
Query: 701 -AKKLLKDINIWLSEVTELQEDLNKE--------SKEKQDLEKRVLELTSKLEK 567
+K D+ SE+ +++EDL K+ KE++DLEK +T ++ +
Sbjct: 5299 MLEKEKHDLEKTRSELYKVKEDLEKQKENTLAEIQKEREDLEKMNENITREMHE 5352
Score = 93.2 bits (230), Expect = 8e-16
Identities = 131/541 (24%), Positives = 244/541 (45%), Gaps = 54/541 (9%)
Frame = -3
Query: 2027 DELLNEKDDK-----KCIVNDRNILEAAKQALE------YKVA-DLEAAKTTLNDELERK 1884
D +LNEK+ K I +D+++LE + LE YKV DLE K E++++
Sbjct: 5732 DMVLNEKNRDIEEKIKSIQSDKDMLEKERHNLEKTRSELYKVKEDLEKQKENTLAEIQKE 5791
Query: 1883 KDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNI 1704
++D + + + + + ++K Q +Q+ D + L+ I
Sbjct: 5792 REDVEKM-NENITREMHEIKHQEEQMNQKQDE--------------------LDQLKTEI 5830
Query: 1703 LILHEELQKEKD----DKTALIKDLVAAEPGKR--TVNEIVSHLESKSRSL-KEHFLREE 1545
L +EL+KEK+ D++ DL +E K+ +N+I+ ++++ + L K+ EE
Sbjct: 5831 QNLQQELEKEKEIIMKDRSQF--DLRQSELDKQQTNMNDIMETMKNERKQLDKDKEEMEE 5888
Query: 1544 EDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLD 1365
+ + +E+ + + +++L+ K K E E K LE+ E R +
Sbjct: 5889 QKQEMEKEKHDFDQSRKSLDKDLKMMKLQKQVFEEEKNKLEQMKIELEREADEIRKIKEE 5948
Query: 1364 TMDAIHE-----EELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRD 1200
T + EEL+KEK + L E+ + E+ +LD + N++L D
Sbjct: 5949 TQNERQSLEKMTEELKKEKESFTHLAEDTK--------KEQEILD---KVKVANESLMAD 5997
Query: 1199 LDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIER--KLEASNLTHNDELHKEKDDK 1026
L + EK LE+ ++ + + + +E + +L+A E+ KEK +
Sbjct: 5998 LQK---EKSNLEEMRENISKQTEDVENKKENLRLREDELWQLQAEIYKQQREIEKEKIN- 6053
Query: 1025 KSIMNDLDRVKAEKQVLESKVSDLETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLE 846
+++E+ + V DL+ +L+ + + D EAF NER+ L+ +K LE
Sbjct: 6054 ---------IESERAAIIKNVEDLQHKIISLDRDSESLKLDREAFENEREVLKQMKTELE 6104
Query: 845 KRVLDLE----ATIHD---IEMKTG---KD-DDYNEAEKQT------LKKRISELEEAI- 720
+ ++E T HD +E T KD D N ++T L ++ ++E+ I
Sbjct: 6105 READEIEKIKLETQHDRQRVEEMTAQIQKDRDKINNLIEETNRKDMVLNEKNRDIEKKIK 6164
Query: 719 SILTDK--AKKLLKDINIWLSEVTELQEDLNKE--------SKEKQDLEKRVLELTSKLE 570
SI +DK +K D+ SE+ +++EDL K+ KE++DLEK +T ++
Sbjct: 6165 SIQSDKDMLEKEKHDLEKTRSELYKVKEDLEKQKENTLAQIQKEREDLEKMNENITREMH 6224
Query: 569 K 567
+
Sbjct: 6225 E 6225
Score = 91.7 bits (226), Expect = 2e-15
Identities = 117/514 (22%), Positives = 225/514 (43%), Gaps = 33/514 (6%)
Frame = -3
Query: 2027 DELLNEKDDK-----KCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAI 1863
D +LNE D K I +D+++LE + LE ++L AK L + E ++ D +
Sbjct: 4192 DMVLNEMDRDIEEKIKSIQSDKDMLEKERHNLEKTRSELARAKENLETQREIERKDIEKM 4251
Query: 1862 IKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEEL 1683
KK + + + ++K Q Q+ D + L+ I L +EL
Sbjct: 4252 -KKNISREMHEIKHQEEQMKQKQDE--------------------LDQLKTEIQNLQQEL 4290
Query: 1682 QKEKDD--KTALIKDLVAAEPGKR--TVNEIVSHLESKSRSL-KEHFLREEEDEVLERSA 1518
+KEK+ K DL +E K+ +N+I+ ++++ + L K+ EE+ + +E+
Sbjct: 4291 EKEKEIIMKARSQLDLRQSELDKQQTNMNDIMETMKNERKQLDKDKEETEEQKQEMEKEK 4350
Query: 1517 SNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHEEE 1338
+ + +E+L+ K K + E E K K LER A +E
Sbjct: 4351 HDFDQSRKSLDEDLKMMKLQKQVIEE-----EKSKLKQMKIELEREA-----------DE 4394
Query: 1337 LRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKR 1158
+RK K + T+N E+Q EK L+ L++ +R + K A E
Sbjct: 4395 IRKVKEE----TQN------ERQIFEKMTEALKKEREDLSEDAKRKNQVLDEMKVANEST 4444
Query: 1157 CSDLEAKNASLTDNQEG---HEAEIERKLEASNLTHND------ELHKEKDDKKSIMNDL 1005
+D+ + ++L + +E ++E K E L E+HK++ + + +++
Sbjct: 4445 LADILRERSNLQEMRENISKQTEDVENKKEKIRLREEKLKQLQAEIHKQQSETEKEKSNI 4504
Query: 1004 DRVKAEKQVLESKVSDLETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLE 825
+R E+ + V DL++ +L+ + + D EAF NE++ L+ +K LE+ ++E
Sbjct: 4505 ER---ERAAIIKDVEDLQSKIISLDRDAESLKLDREAFENEKEELKQMKTELEREADEIE 4561
Query: 824 ----ATIHDIEMKTGKDDDYNEA----------EKQTLKKRISELEEAISILTDKAKKLL 687
T H+ + D+ E K+ ++++ E+E+ + K L
Sbjct: 4562 KIKLETQHERQRVEEMTADFMETMNNERKQLNKNKEEMQEQKQEMEKERHDMDQSRKSLD 4621
Query: 686 KDINIWLSEVTELQEDLNKESKEKQDLEKRVLEL 585
K++ + + ++E+ NK + K +LEK E+
Sbjct: 4622 KNLKMMKLQKQVIEEEKNKLEQMKIELEKEADEI 4655
Score = 89.0 bits (219), Expect = 2e-14
Identities = 123/538 (22%), Positives = 234/538 (43%), Gaps = 24/538 (4%)
Frame = -3
Query: 2081 QALESKVSVFEAAIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLN 1902
Q +E + E A L E + + ++ I NDR E L+ + D+E + +
Sbjct: 2805 QIIEDERDKIEQIKAELQKEAKDTEKQRQDIENDRRNNEEMVIKLQNEKKDIETSTDRIR 2864
Query: 1901 DE-------LERKKDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXX 1743
DE +R + D + + K+ D + K + +D E + +
Sbjct: 2865 DEEANLRVLKQRLESDRDTLEKERFDLK----KTNTEMKDLEKQLESQNRQHEIQLAEIQ 2920
Query: 1742 XXXKIVSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKE 1563
+I+ L++ + E+L+KE+D D+ E E+ E +
Sbjct: 2921 KEREILEQLKLTLSKQKEDLEKERDCFEKEKADISLRE-------ELQEQSEREGIGKTR 2973
Query: 1562 HFLREEEDEVLE------RSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLE 1401
+++E DE+ + + N + K I E+E K + K+ L + E E +++ +E
Sbjct: 2974 VRIKKEMDELKQTRLNVVKELENNELQKQIIEDERDKIEQIKAELQKEAEDTEKQRRDIE 3033
Query: 1400 K---------TVLERRASNLDT-MDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTV 1251
K L+ +++T D I +EE E V K L + + E E+ EKT
Sbjct: 3034 KDRRNNEEMVIKLQNEKKDIETSTDRIRDEEANLE-VQKQRLESDRDTLEKERFDLEKTK 3092
Query: 1250 LDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIE-RKLEA 1074
++ +L L+ + + + ++K LE +L+ +E E E + + E
Sbjct: 3093 TEM----GNLKKQLESQIRQHEIQLVEIQKEREILEQLKINLSKQKEDLEKERDCFEKEK 3148
Query: 1073 SNLTHNDELHKEKDDKKSIMNDLDRVKAEKQVLESKVSDLETTYSTLNNELQQKMDDNEA 894
++++ +++L KE+ +++ I N R+K E LE +L NNELQ+K+ +
Sbjct: 3149 ADISLSEDL-KEQSEREGIDNTRTRIKQEMDELEKTRQNLAKEQE--NNELQKKIIE--- 3202
Query: 893 FLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISI 714
+ERD +E +K L+K EA +E+ +++ N E T K+ E E+++
Sbjct: 3203 --DERDKIEQIKAELKK-----EAEKTKLEL---QNERQNLEEAGTKLKKDRENVESLAE 3252
Query: 713 LTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLELTSKLEKCICGARDGL 540
+ + +L+++ I TE+Q N+ +K+ Q+ RVL K I GA++ L
Sbjct: 3253 ELGRKQVVLENMQI----ETEMQRKANESNKQMQE---RVLIELKKTVTDIAGAKEDL 3303
Score = 88.2 bits (217), Expect = 3e-14
Identities = 122/534 (22%), Positives = 228/534 (42%), Gaps = 35/534 (6%)
Frame = -3
Query: 2042 IATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAI 1863
I+ L + + NEK+ K ++ L+ Q + K+ D+E KT + E A
Sbjct: 5556 ISKLKEYIDNEKEKSKLREDELKKLQTEVQKQQSKI-DME--KTNIESE--------RAA 5604
Query: 1862 IKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEEL 1683
+ + +++LK + D E M ++ + V NL+ ++ L +
Sbjct: 5605 MIREKQNMMTELKKKS--EDVEIQMKEILTEKELLHNDRKLLTRDVENLQQKLIDLERDS 5662
Query: 1682 QKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVL---ERSASN 1512
++ K D+ A + A + K + +E + R EE ER N
Sbjct: 5663 KRLKLDREAFENEKEAMKQMKTDLQIQADEIEKIKLETQHDRQRVEEMAAQIQKERDKIN 5722
Query: 1511 LAIMKAIREEELRKEKDGK-----SALVENGEGCEAEKQGLEKTV---------LERRAS 1374
I + R++ + EK+ ++ + + E E+ LEKT LE++
Sbjct: 5723 NLIEETNRKDMVLNEKNRDIEEKIKSIQSDKDMLEKERHNLEKTRSELYKVKEDLEKQKE 5782
Query: 1373 NLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKT--VLDLEPTIPSLNDALQRD 1200
N T+ I +E EK++++ E E E+Q +K + L+ I +L L+++
Sbjct: 5783 N--TLAEIQKEREDVEKMNENITREMHEIKHQEEQMNQKQDELDQLKTEIQNLQQELEKE 5840
Query: 1199 LDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIER--KLEASNLTHNDELHKEKDD- 1029
+ +M ++ + R S+L+ + ++ D E + E ++ K + E+ KEK D
Sbjct: 5841 KEIIMKDRSQFDLRQSELDKQQTNMNDIMETMKNERKQLDKDKEEMEEQKQEMEKEKHDF 5900
Query: 1028 ---KKSIMNDLDRVKAEKQVLESKVSDLETTYSTLNNELQQKMDDNEAFLNERDGLEAVK 858
+KS+ DL +K +KQV E + + LE L E + E NER LE +
Sbjct: 5901 DQSRKSLDKDLKMMKLQKQVFEEEKNKLEQMKIELEREADEIRKIKEETQNERQSLEKMT 5960
Query: 857 QGLEKRVLDLEATIHDIEMKTGKDDDY-------NE---AEKQTLKKRISELEEAISILT 708
+ L+K + E+ H E T K+ + NE A+ Q K + E+ E IS T
Sbjct: 5961 EELKK---EKESFTHLAE-DTKKEQEILDKVKVANESLMADLQKEKSNLEEMRENISKQT 6016
Query: 707 DKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLELTSKLEKCICGARD 546
+ + +++ + E+ +LQ ++ K+ +E +EK + + S+ I D
Sbjct: 6017 EDVENKKENLRLREDELWQLQAEIYKQQRE---IEKEKINIESERAAIIKNVED 6067
Score = 87.8 bits (216), Expect = 3e-14
Identities = 125/549 (22%), Positives = 249/549 (45%), Gaps = 43/549 (7%)
Frame = -3
Query: 2027 DELLNEKDDK-----KCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAI 1863
D +LNEK+ K I +D+++LE K LE ++L K ++LE++K++ A
Sbjct: 3736 DMVLNEKNRDIEEKIKSIQSDKDMLEKEKHNLEKTRSELYKVK----EDLEKQKENTLAE 3791
Query: 1862 IKKA---LDKRISDLKADAPQ-RDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILIL 1695
I+K L+K ++ + + + QE+ M + L+ I L
Sbjct: 3792 IQKEREDLEKMNENITIEMHEIKHQEEQMKQ--------------KQDELDQLKTEIQNL 3837
Query: 1694 HEELQKEKD----DKTALIKDLVAAEPGKR--TVNEIVSHLESKSRSL-KEHFLREEEDE 1536
+EL+KEK+ D++ L DL +E K+ +N+I+ ++++ + L K+ EE+ +
Sbjct: 3838 QQELEKEKEIIMKDRSEL--DLRQSELDKQQTNMNDIIETMKNERKLLDKDKEEMEEQKQ 3895
Query: 1535 VLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMD 1356
+E+ N+ +E+L+ K K + E E K L++ E R +T +
Sbjct: 3896 EMEKERDNMDQSIKSLDEDLKMMKLQKQVIEEEKNKLEQMKFELQREADEIRKIKEETQN 3955
Query: 1355 AIHEEELRKEKVDKSALTENGEGCE-AEKQGPEKTVLD-LEPTIPSLNDALQRDLDRVMA 1182
E EK+ K+ + E + AE EK +LD ++ S LQR+ +
Sbjct: 3956 ----ERQSLEKMTKALIKEREDLVHLAEYTKREKEMLDEMQVANKSSMADLQREKRILEE 4011
Query: 1181 EKQALEKRCSDLE---AKNASLTDNQEGHEAEIERK-----LEASNLTHN---------- 1056
++ + K+ D+E K+ D + + E++++ +E +N+
Sbjct: 4012 MRENISKQTEDIENEKEKSKLREDELKKLQTEVQKQQSEIDMEKTNIESERAVMIREKQN 4071
Query: 1055 --DELHKEKDD----KKSIMNDLDRVKAEKQVLESKVSDLETTYSTLNNELQQKMDDNEA 894
EL K+ +D K I+ + + ++ + +L+ + DL+ ++ + + D EA
Sbjct: 4072 MMTELKKKSEDVEIQMKEILTEKELLENDSNLLKKDMEDLKQKLMSIERDSESLKLDREA 4131
Query: 893 FLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISI 714
F NE++ L+ +K L+ + ++E I+++T D E + ++K E+ I +
Sbjct: 4132 FGNEKEVLKQMKTDLQIQADEIE----KIKLETQHDRQRVEEKTAQIQKDRDEINNLI-V 4186
Query: 713 LTDKAKKLLKDINIWLSE-VTELQEDLNKESKEKQDLEKRVLELTSKLEKCICGARDGLS 537
T++ +L +++ + E + +Q D + KE+ +LEK EL A++ L
Sbjct: 4187 ETNRKDMVLNEMDRDIEEKIKSIQSDKDMLEKERHNLEKTRSELAR--------AKENLE 4238
Query: 536 TIKEAWMSD 510
T +E D
Sbjct: 4239 TQREIERKD 4247
Score = 87.0 bits (214), Expect = 6e-14
Identities = 104/492 (21%), Positives = 228/492 (46%), Gaps = 21/492 (4%)
Frame = -3
Query: 2012 EKDDKKCIVNDRNI----LEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKALD 1845
EKD K N++N+ L A + L+ + A++E K L + ++R + + I K+
Sbjct: 2487 EKDRLKLQENEQNMQMSQLNAKQNELDERQAEMEKQKRELENVMDRLEKEKVEITKEK-- 2544
Query: 1844 KRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDD 1665
+R+++++ + +++ D+ + ++E + IL+ EL+K K+
Sbjct: 2545 QRVNEMQNEVKRKNASVDL------------IKQEVLREQDHIENSREILNRELEKIKEK 2592
Query: 1664 KTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNLAIMKAIRE 1485
KT L ++ A + K + + + L L ++E E E+ ++ + E
Sbjct: 2593 KTILAEEFEALDDKKEMIGKEMQRLGKMKAEL------QKEAEDTEKQRRDIDNDRRNNE 2646
Query: 1484 EELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHEEELRKEKVDKSAL 1305
E + K ++ K + + + E+ L + +R S+ DT++ +L K K + L
Sbjct: 2647 EMVIKLQNEKKDIETSTDRIRDEEANL-RVQKQRLESDRDTLEK-ERFDLEKTKTEMKDL 2704
Query: 1304 TENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASL 1125
+ + E Q + + +E I + L++ + +K+ LEK E + A +
Sbjct: 2705 EK-----QLESQSRQHEIQLVE--IQKEREILEQLKINLSKQKEDLEKERDCFEKEKADI 2757
Query: 1124 TDNQEGHEAEIERKLEASNLTHNDELHKEKDDKKSIMNDLDRVKAEKQVLESKVSDLETT 945
+ +E E + ++ + + E+ + + + +++ +L+ + +KQ++E + +E
Sbjct: 2758 SLREELEEQSEKEGIDKTRVRIKQEMDELEQTRLNVVKELENNELQKQIIEDERDKIE-- 2815
Query: 944 YSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTG--KDDDYN- 774
+ ELQ++ D E +R +E ++ E+ V+ L+ DIE T +D++ N
Sbjct: 2816 --QIKAELQKEAKDTE---KQRQDIENDRRNNEEMVIKLQNEKKDIETSTDRIRDEEANL 2870
Query: 773 -------EAEKQTLKKRISELEEAISILTDKAKKL---LKDINIWLSEVTELQEDLNK-- 630
E+++ TL+K +L++ + + D K+L + I L+E+ + +E L +
Sbjct: 2871 RVLKQRLESDRDTLEKERFDLKKTNTEMKDLEKQLESQNRQHEIQLAEIQKEREILEQLK 2930
Query: 629 --ESKEKQDLEK 600
SK+K+DLEK
Sbjct: 2931 LTLSKQKEDLEK 2942
Score = 85.9 bits (211), Expect = 1e-13
Identities = 115/526 (21%), Positives = 234/526 (44%), Gaps = 34/526 (6%)
Frame = -3
Query: 2042 IATLNDELLNEKDDKKCIV----NDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDD 1875
+A L+ EL KD+ + I +R+ +E + L ++ +E + D+ ++
Sbjct: 9644 MADLSRELQKAKDELEKIAYKTNKERHEVEQMQAELHSQIQAIEQQGQIMQDKQNHLEEK 9703
Query: 1874 NNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVN---- 1707
+I +K + +I + + Q +QE N L I N + N
Sbjct: 9704 ELSIQRKEEEIKIGNTEF---QIEQEHLNNVLEETNKRQHDLEVMRADIELNKQKNNKDF 9760
Query: 1706 --ILILHEELQKEKDD--------KTALIKDLVAAEPGKRTVNEIVSHLESK-SRSLKEH 1560
+ + EL+ EK D K + L E K + ++ L+SK ++ KE
Sbjct: 9761 ELLEKIRSELENEKYDLQIWTEQQKHLVEVQLQELEKEKERLEKMEIELQSKREQTEKEK 9820
Query: 1559 FLREEEDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLE--KTVLE 1386
+ ++R + + + + + + K+ L E E + E++ LE K +++
Sbjct: 9821 ADLNRVNAEIQREKQVIDKKRHMTNRAMEELETIKTELKERQEKIQTEQEKLEEEKLLVQ 9880
Query: 1385 RRASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDA-- 1212
A NL+ + + + K ++ ++ L E CE ++ E+ D+E I + +A
Sbjct: 9881 IEAENLNKVLEEIKRQQEKLEISEADLKVMKEQCENAREETERKKCDIEEQIQNNENAKH 9940
Query: 1211 -LQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEI--ERKL--EASN--LTHND 1053
L+++ + +KQ L+K+ DL+ + + +N E + + E+KL + +N L D
Sbjct: 9941 LLEQERKDIDKQKQELQKQADDLDMRMIAHRENVEMSKRSLDEEKKLLEQKANEILRQRD 10000
Query: 1052 ELHKEKDDKKSIMNDLDRVKAEKQVLESKVSDLETTYSTLNNEL---QQKMDDNEAFLNE 882
+L KEK+D N LD ++ E Q + +++ NE+ QQ+++++ +NE
Sbjct: 10001 DLEKEKEDMMKKWNKLDVLQNEMQNENKAMEEIKYELDGKRNEINKEQQRLEESLRAINE 10060
Query: 881 RDG-LEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTD 705
G LE ++ EK+ +E + +M E++ L + SELE+ + +
Sbjct: 10061 EKGDLEIMRADYEKQEQQIEEMRVEAKM-----------ERKELDQIKSELEKDKTEIDY 10109
Query: 704 KAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLELTSKLEK 567
+ KKL D N+ E +L++ ++ ++Q +E EL K+++
Sbjct: 10110 EWKKLNNDRNMIEKERNDLEKMKSELMTQRQQMEDERSELDQKIKE 10155
Score = 85.5 bits (210), Expect = 2e-13
Identities = 111/536 (20%), Positives = 235/536 (43%), Gaps = 46/536 (8%)
Frame = -3
Query: 2072 ESKVSVFEAAIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDEL 1893
E+K ++ E +E+ EK+ ++ R +E ++ +E + LE ++ ++ E
Sbjct: 12013 ETKANILEMKTKAEPEEIKKEKEKEEEEQEMRVKVEMERKEIEQIKSQLERVRSEMDHEQ 12072
Query: 1892 ERKKDDNNAII--KKALDKRISDLKADAPQRDQE-DDMNALIXXXXXXXXXXXXXXKIVS 1722
++ DD I K+ L+K S++ Q ++E +++ I +IV
Sbjct: 12073 KKLNDDKKMIEQEKEDLEKMKSEIMKQRQQMEEERSELDKKIKQTDLEKHDIENSKEIVE 12132
Query: 1721 NLEVNILILHEELQKEK-----------DDKTALIKDLVAAEPGKRTVNEIVSHLESKSR 1575
L V + E+Q +K D++ LI++ + + + E+ ++ +
Sbjct: 12133 KLMVEVEKQKHEIQFQKEELDIERQKIADEQDLLIQNKIEQQNENERIKEMDEEIKKERE 12192
Query: 1574 SLKEHFL-----REEEDEVLE---RSASNLAIMKAIREEELRKEKDGKSALVENGEGCEA 1419
+LKE + +EE + V+E R +L M E+ + + + L + E
Sbjct: 12193 TLKEMEVNLQKEKEEIESVIEETQRRKEDLEKMSTDINEQKQDLMNQRDLLKQ-----ER 12247
Query: 1418 EKQGLEKTVLERRASNLDTMDAI-----------HEEELRKEKVDKSALTENGEGCEAEK 1272
E+ + T L++R +T I +E+L++ + ++ E E
Sbjct: 12248 EEMNHKLTQLQQRIDEFETTSNILVTTKMEEKTEMDEKLQQAIKEYESIIEETNRKRTEL 12307
Query: 1271 QGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEI 1092
+ E + ++ D L+++ E++ L+K+ DLE + D +E + +
Sbjct: 12308 EEIEVDQSQQNKNVETMKDLLEKERKDTEKEREELQKQADDLEMQMIEHGDKEEMSKRSL 12367
Query: 1091 --ERKL--EASN--LTHNDELHKEKDDKKSIMNDLDRVKAEKQVLESKVSDLETTYSTLN 930
E+KL + +N L D+L KEK+D N+LD ++ E Q ++++ +++ T
Sbjct: 12368 DEEKKLLEQKANEILRQRDDLEKEKEDMMKKWNELDGLQKEIQNQKNEMEEIKCELETKR 12427
Query: 929 NELQQKMDDNEAFLN----ERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKD-DDYNEAE 765
E+ ++ E LN ER LE V+ EK + I ++ +KT + D+ ++
Sbjct: 12428 IEIIKEQKRLEESLNTVNEERQYLEIVRVDYEKH----QQQIEEMRVKTKMERDELDQLM 12483
Query: 764 KQTL--KKRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLE 603
+ L +K ++ I +L + ++ +++ ++ EL+ + K EK+DLE
Sbjct: 12484 AKMLMDRKENERSKDMIGLLKKEMEQTKFNLD---AQEEELKLEKQKIQNEKKDLE 12536
Score = 84.7 bits (208), Expect = 3e-13
Identities = 119/558 (21%), Positives = 246/558 (44%), Gaps = 48/558 (8%)
Frame = -3
Query: 2075 LESKVSVFEAAIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDE 1896
L+ + S + +ND + K+++K + D+ E KQ +E + D + ++ +L+++
Sbjct: 4981 LDLRQSELDKQQTNVNDIMETMKNERKQLDKDKEETEEQKQEMEKEKHDFDQSRKSLDED 5040
Query: 1895 LERKKDDNNAII--KKALDKRISDLKADAPQ--RDQEDDMNALIXXXXXXXXXXXXXXKI 1728
L+ K + K L++ +L+ +A + + +E+ N +
Sbjct: 5041 LKMMKLQKQVLEDEKSKLEQMKIELEREAVEIRKIKEEIQNERQNLEKMTEALKEEREDL 5100
Query: 1727 VSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLK--EHFL 1554
+ N +L E + ++++ E + +++ +E+K +L+ E L
Sbjct: 5101 AEETKKNNQVLDEMKVANESTLADILREKSNLEEMRENISKQTEDVENKKENLRLREDEL 5160
Query: 1553 REEEDEV------LERSASNL-----AIMKAIREEELR---KEKDGKSALVENGEGCEAE 1416
R+ + E+ +E+ N+ AI+K + + + + ++D +S ++ E E E
Sbjct: 5161 RQLQAEIHKQQREIEKEKINIESERAAIIKDVEDLQHKIICLDRDAESLKLDR-EAFENE 5219
Query: 1415 KQGLE--KTVLERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCEA----EKQGPEKT 1254
K+ L+ KT LER A ++ + E + +++V++ A + E E+ +
Sbjct: 5220 KEVLKQMKTELEREADEIEKIKL--ETQHDRQRVEEMAAQIQKDRDEINNLIEETNRKDM 5277
Query: 1253 VL-----DLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIE 1089
VL D+E I S+ Q D D + EK LEK S+L L +E AEI+
Sbjct: 5278 VLNEKNRDIEEKIKSI----QSDKDMLEKEKHDLEKTRSELYKVKEDLEKQKENTLAEIQ 5333
Query: 1088 RKLEA-----SNLT-------HNDELHKEKDD-----KKSIMNDLDRVKAEKQVLESKVS 960
++ E N+T H +E +K D K I N ++ EK+++ S
Sbjct: 5334 KEREDLEKMNENITREMHEIKHQEEQMNQKQDELDQLKTEIQNLQQELEKEKEIIMKDRS 5393
Query: 959 DLETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDD 780
L+ S L+ + D E NER L+ K+ +E++ ++E +++ D+
Sbjct: 5394 QLDLRQSELDKQQTNMNDIMETMKNERKQLDKDKEEMEEQKQEMEKERDNMDQSRKSLDE 5453
Query: 779 YNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEK 600
+ +K L+K++ E E+ +K +++ ++ E+++++E+ ++Q LEK
Sbjct: 5454 --DQKKMKLQKQMFEEEK------NKLEQMKIELEREADEISKIKEE---TQNKRQRLEK 5502
Query: 599 RVLELTSKLEKCICGARD 546
EL + E A D
Sbjct: 5503 MTEELIREKESLAHLAED 5520
Score = 84.0 bits (206), Expect = 5e-13
Identities = 103/498 (20%), Positives = 216/498 (43%), Gaps = 12/498 (2%)
Frame = -3
Query: 2075 LESKVSVFEAAIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDE 1896
L+ + S + +ND + K+++K + D+ E KQ +E + D + ++ +L+++
Sbjct: 4304 LDLRQSELDKQQTNMNDIMETMKNERKQLDKDKEETEEQKQEMEKEKHDFDQSRKSLDED 4363
Query: 1895 LERKKDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNL 1716
L+ K + K+ +++ S LK + ++E D + N
Sbjct: 4364 LKMMK-----LQKQVIEEEKSKLKQMKIELEREADEIRKVKEE-------------TQNE 4405
Query: 1715 EVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEED- 1539
+ E L+KE++D +E KR N+++ ++ + S LRE +
Sbjct: 4406 RQIFEKMTEALKKERED---------LSEDAKRK-NQVLDEMKVANESTLADILRERSNL 4455
Query: 1538 -EVLERSASNLAIMKAIREE-ELRKEKDGKSALVENGEGCEAEKQGLEKTVLER-RASNL 1368
E+ E + ++ +E+ LR+EK + + + E EK EK+ +ER RA+ +
Sbjct: 4456 QEMRENISKQTEDVENKKEKIRLREEKLKQLQAEIHKQQSETEK---EKSNIERERAAII 4512
Query: 1367 DTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRV 1188
++ + + + ++ D +L + E E EK+ ++ +LE +++++
Sbjct: 4513 KDVEDLQSKIISLDR-DAESLKLDREAFENEKEELKQMKTELEREAD--------EIEKI 4563
Query: 1187 MAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASNLTHNDELHKEKDDKKSIMND 1008
E Q +R ++ A +N+ + + +++ E H +KS+ +
Sbjct: 4564 KLETQHERQRVEEMTADFMETMNNERKQLNKNKEEMQEQKQEMEKERHDMDQSRKSLDKN 4623
Query: 1007 LDRVKAEKQVLESKVSDLETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDL 828
L +K +KQV+E + + LE L E + E NER LE + + L+K
Sbjct: 4624 LKMMKLQKQVIEEEKNKLEQMKIELEKEADEIRKIKEETQNERQRLEKMTEELKKEKESF 4683
Query: 827 EATIHDI--------EMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLLKDINI 672
D +MK + + +K+ K + E+ E IS T+ ++K + I +
Sbjct: 4684 THLAEDTKTEKKILDKMKVANESLMADLQKE--KSNLEEMRENISKQTEDSEKEKEKIRL 4741
Query: 671 WLSEVTELQEDLNKESKE 618
E+ +LQ +++K+ E
Sbjct: 4742 REDELEQLQAEIHKQQGE 4759
Score = 83.6 bits (205), Expect = 7e-13
Identities = 126/569 (22%), Positives = 237/569 (41%), Gaps = 71/569 (12%)
Frame = -3
Query: 2081 QALESKVSVFEAAIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLN 1902
Q LE + S E L E + + K+ I N+R LE +AL+ + DL N
Sbjct: 5049 QVLEDEKSKLEQMKIELEREAVEIRKIKEEIQNERQNLEKMTEALKEEREDLAEETKKNN 5108
Query: 1901 DELERKKDDNNAIIKKALDKR---------ISDLKADAPQRDQ-----EDDMNALIXXXX 1764
L+ K N + + L ++ IS D + + ED++ L
Sbjct: 5109 QVLDEMKVANESTLADILREKSNLEEMRENISKQTEDVENKKENLRLREDELRQLQAEIH 5168
Query: 1763 XXXXXXXXXXKIVSNLEVNILILHEELQKE----KDDKTALIKDLVAAEPGKRTVNEIVS 1596
+ + I+ E+LQ + D +L D A E K + ++ +
Sbjct: 5169 KQQREIEKEKINIESERAAIIKDVEDLQHKIICLDRDAESLKLDREAFENEKEVLKQMKT 5228
Query: 1595 HLESKSRSLKEHFLREEEDEVL----------ERSASNLAIMKAIREEELRKEKDGK--- 1455
LE ++ +++ L + D +R N I + R++ + EK+
Sbjct: 5229 ELEREADEIEKIKLETQHDRQRVEEMAAQIQKDRDEINNLIEETNRKDMVLNEKNRDIEE 5288
Query: 1454 --SALVENGEGCEAEKQGLEKTV---------LERRASNLDTMDAIHEEELRKEKVDKSA 1308
++ + + E EK LEKT LE++ N T+ I +E EK++++
Sbjct: 5289 KIKSIQSDKDMLEKEKHDLEKTRSELYKVKEDLEKQKEN--TLAEIQKEREDLEKMNENI 5346
Query: 1307 LTENGEGCEAEKQGPEKT--VLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKN 1134
E E E+Q +K + L+ I +L L+++ + +M ++ L+ R S+L+ +
Sbjct: 5347 TREMHEIKHQEEQMNQKQDELDQLKTEIQNLQQELEKEKEIIMKDRSQLDLRQSELDKQQ 5406
Query: 1133 ASLTDNQEGHEAEIER--KLEASNLTHNDELHKEKDD----KKSIMNDLDRVKAEKQVLE 972
++ D E + E ++ K + E+ KE+D+ +KS+ D ++K +KQ+ E
Sbjct: 5407 TNMNDIMETMKNERKQLDKDKEEMEEQKQEMEKERDNMDQSRKSLDEDQKKMKLQKQMFE 5466
Query: 971 SKVSDLETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGL----------------EKR 840
+ + LE L E + E N+R LE + + L EK+
Sbjct: 5467 EEKNKLEQMKIELEREADEISKIKEETQNKRQRLEKMTEELIREKESLAHLAEDTKTEKK 5526
Query: 839 VLDLEATIHDIEMKTGKDDDYNEAEK-----QTLKKRISELEEAISILTDKAKKLLKDIN 675
+LD EMK + + ++ + +++ IS+L+E I +K K L++
Sbjct: 5527 ILD--------EMKVANESSMADLQREKSILEEMRENISKLKEYID--NEKEKSKLRE-- 5574
Query: 674 IWLSEVTELQEDLNKESKEKQDLEKRVLE 588
E+ +LQ ++ K+ + K D+EK +E
Sbjct: 5575 ---DELKKLQTEVQKQ-QSKIDMEKTNIE 5599
Score = 81.3 bits (199), Expect = 3e-12
Identities = 112/514 (21%), Positives = 217/514 (42%), Gaps = 22/514 (4%)
Frame = -3
Query: 2042 IATLNDELLNEKDDKKC-----------IVNDRNILEAAKQALEYKVADLEAAKTTLNDE 1896
I+ +++ NEK+ K + ++ ++ K +E + A + K + E
Sbjct: 4016 ISKQTEDIENEKEKSKLREDELKKLQTEVQKQQSEIDMEKTNIESERAVMIREKQNMMTE 4075
Query: 1895 LERKKDDNNAIIKKAL-DKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSN 1719
L++K +D +K+ L +K + + ++ ++D ED L+ +
Sbjct: 4076 LKKKSEDVEIQMKEILTEKELLENDSNLLKKDMEDLKQKLMSIERDSESLKLDREAFGNE 4135
Query: 1718 LEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEED 1539
EV + + +LQ + D+ + K + + ++ V E + ++ K R E +
Sbjct: 4136 KEV-LKQMKTDLQIQADE---IEKIKLETQHDRQRVEEKTAQIQ-KDRD-------EINN 4183
Query: 1538 EVLERSASNLAIMKAIR--EEELRKEKDGKSALVENGEGCEAEKQGLEKT--VLERRASN 1371
++E + ++ + + R EE+++ + K L E E+ LEKT L R N
Sbjct: 4184 LIVETNRKDMVLNEMDRDIEEKIKSIQSDKDML-------EKERHNLEKTRSELARAKEN 4236
Query: 1370 LDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDR 1191
L+T I +++ K K + S + E + + + + L+ I +L L+++ +
Sbjct: 4237 LETQREIERKDIEKMKKNISREMHEIKHQEEQMKQKQDELDQLKTEIQNLQQELEKEKEI 4296
Query: 1190 VMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIER--KLEASNLTHNDELHKEKDD---- 1029
+M + L+ R S+L+ + ++ D E + E ++ K + E+ KEK D
Sbjct: 4297 IMKARSQLDLRQSELDKQQTNMNDIMETMKNERKQLDKDKEETEEQKQEMEKEKHDFDQS 4356
Query: 1028 KKSIMNDLDRVKAEKQVLESKVSDLETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGL 849
+KS+ DL +K +KQV+E + S L+ L E + E NER E + + L
Sbjct: 4357 RKSLDEDLKMMKLQKQVIEEEKSKLKQMKIELEREADEIRKVKEETQNERQIFEKMTEAL 4416
Query: 848 EKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIW 669
+K DL D + K D+ A + TL DI
Sbjct: 4417 KKEREDLS---EDAKRKNQVLDEMKVANESTLA----------------------DI--- 4448
Query: 668 LSEVTELQEDLNKESKEKQDLEKRVLELTSKLEK 567
L E + LQE SK+ +D+E + ++ + EK
Sbjct: 4449 LRERSNLQEMRENISKQTEDVENKKEKIRLREEK 4482
Score = 80.9 bits (198), Expect = 4e-12
Identities = 119/523 (22%), Positives = 221/523 (42%), Gaps = 20/523 (3%)
Frame = -3
Query: 2075 LESKVSVFEAAIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDE 1896
L++ S E + +L E N +D+K + R+ + + A+ + DLE + E
Sbjct: 9320 LQNMKSNLERQLESLRHEKANVEDEKNALEKMRSESKEIQNAIRKEREDLENCWVEIEGE 9379
Query: 1895 LERKKDDNNAI------IKKALDKRISDLKADAPQRDQE--DDMNALIXXXXXXXXXXXX 1740
+R +++ + IKK +D + + + R+++ + M L+
Sbjct: 9380 KKRMEEETRRLEMHREEIKK-VDSELQKSRENIESREEKINNKMEELLQMKVEMGRTKEE 9438
Query: 1739 XXKIVSNLEVNILILHE---ELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSL 1569
K L+ + L E+Q++ +DK I D+ E + EI L+ +++ L
Sbjct: 9439 IEKESQRLQDATIDLENAKAEIQRQ-EDKFEDIIDIKIQEKER----EIKIQLDKETKRL 9493
Query: 1568 KEHFLREEEDEVLE-----RSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGL 1404
E + +D +E R + K + E+E ++ K K L + EKQ
Sbjct: 9494 SEEIELKVKDLEMEMADMKRQKQEIEDTKGLLEKEKQELKQEKKELEDQMMDLTREKQET 9553
Query: 1403 EKTVLERRASNLDTMDAIHEEELRKEKV--DKSALTENGEGCEAEKQGPEKTVLDLEPTI 1230
E+ A D E E+ KEK+ +KS + E +++ ++T + +
Sbjct: 9554 EEERNNLMALKNQLEDLRKENEIVKEKLTLEKSNIEEMQLKIFKQQRLNDQTREENKKE- 9612
Query: 1229 PSLNDALQRDLDRVMAEKQALEKRCSDL-EAKNASLTDNQEGHEAEIERKLEASNLTHND 1053
++L++ +KQ LE + + E KN ++E +A+ E LE N
Sbjct: 9613 ---KESLEQQRFETEQQKQMLEISTTKMMEEKNEMADLSRELQKAKDE--LEKIAYKTNK 9667
Query: 1052 ELHKEKDDKKSIMNDLDRVKAEKQVLESKVSDLETTYSTLNNELQQKMDDNEAFLNERDG 873
E H+ + + + + + ++ + Q+++ K + LE ++ + ++ N F E++
Sbjct: 9668 ERHEVEQMQAELHSQIQAIEQQGQIMQDKQNHLEEKELSIQRKEEEIKIGNTEFQIEQEH 9727
Query: 872 LEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKK 693
L V + KR DLE DIE+ K N + + L+K SELE
Sbjct: 9728 LNNVLEETNKRQHDLEVMRADIELNKQK----NNKDFELLEKIRSELENE---------- 9773
Query: 692 LLKDINIWLSEVTELQE-DLNKESKEKQDLEKRVLELTSKLEK 567
D+ IW + L E L + KEK+ LEK +EL SK E+
Sbjct: 9774 -KYDLQIWTEQQKHLVEVQLQELEKEKERLEKMEIELQSKREQ 9815
Score = 80.1 bits (196), Expect = 7e-12
Identities = 122/570 (21%), Positives = 236/570 (41%), Gaps = 68/570 (11%)
Frame = -3
Query: 2075 LESKVSVFEAAIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLE--AAKTTLN 1902
+E+K + L D+ + K+D+ D LE ++ L + DLE +
Sbjct: 9136 METKKRSLDRMSRELQDDKIRLKNDRDAYEKDMTHLELKREELVRETEDLERKILQQREQ 9195
Query: 1901 DELERKKDDNNA---------IIKK-----------------------ALDKRISDLKAD 1818
DE+ ++ +N I+KK AL + S+L+
Sbjct: 9196 DEMAKRDIENQTEALEVMKVDILKKRNEFAKEMENVHSERQKLLLLQGALQSQESELENR 9255
Query: 1817 APQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDKTALIKDLV 1638
+Q+ A + + + L EELQ+EK ++ + K+ +
Sbjct: 9256 VFMEEQKHLKQAKAETEECRKQLAEMSETVTTE-QNEYRKLIEELQREK-EQLEISKNQI 9313
Query: 1637 AAEPGKRTVNEIVSHLESKSRSLK-EHFLREEEDEVLERSAS-NLAIMKAIREEELRKEK 1464
E K+ + + S+LE + SL+ E E+E LE+ S + I AIR+E
Sbjct: 9314 EQE--KKDLQNMKSNLERQLESLRHEKANVEDEKNALEKMRSESKEIQNAIRKER----- 9366
Query: 1463 DGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHEEELRKEKVDKSALTENGEGC 1284
E+ E C E +G EK +E L+ +H EE++K + EN E
Sbjct: 9367 -------EDLENCWVEIEG-EKKRMEEETRRLE----MHREEIKKVDSELQKSRENIESR 9414
Query: 1283 EAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTD----N 1116
E + + +L ++ + + ++++ R+ LE ++++ + D
Sbjct: 9415 EEKINNKMEELLQMKVEMGRTKEEIEKESQRLQDATIDLENAKAEIQRQEDKFEDIIDIK 9474
Query: 1115 QEGHEAEIERKLEASNLTHNDELHKEKDDKKSIMNDLDRVKAE----KQVLESKVSDLET 948
+ E EI+ +L+ ++E+ + D + M D+ R K E K +LE + +L+
Sbjct: 9475 IQEKEREIKIQLDKETKRLSEEIELKVKDLEMEMADMKRQKQEIEDTKGLLEKEKQELKQ 9534
Query: 947 TYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLE---------KRVLDLE-ATIHDIEMK 798
L +++ + + ER+ L A+K LE K L LE + I ++++K
Sbjct: 9535 EKKELEDQMMDLTREKQETEEERNNLMALKNQLEDLRKENEIVKEKLTLEKSNIEEMQLK 9594
Query: 797 TGKDD-------DYNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQED 639
K + N+ EK++L+++ E E+ +L K++++ N ELQ+
Sbjct: 9595 IFKQQRLNDQTREENKKEKESLEQQRFETEQQKQMLEISTTKMMEEKNEMADLSRELQKA 9654
Query: 638 LN-------KESKEKQDLEKRVLELTSKLE 570
+ K +KE+ ++E+ EL S+++
Sbjct: 9655 KDELEKIAYKTNKERHEVEQMQAELHSQIQ 9684
Score = 79.3 bits (194), Expect = 1e-11
Identities = 93/521 (17%), Positives = 226/521 (43%), Gaps = 46/521 (8%)
Frame = -3
Query: 1991 IVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKALDKR--------- 1839
++N R++L+ ++ + +K L+ + ++ ++K+++ KK ++R
Sbjct: 11681 LMNQRDLLKQEREEINHKWTQLQQRIDEFDAQVSKQKEEDLTKQKKMEEERKSLEETKIK 11740
Query: 1838 ISDLKADAP--------QRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEEL 1683
I ++K ++++E+ M A + I S LE + E
Sbjct: 11741 IIEMKTKTEPEKIKKEKEKEEEEVMRAKVEMKKEELDQ------IKSQLERVRSEIDHEQ 11794
Query: 1682 QKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNLAI 1503
+K DDK + ++ E K + + +E + RS E+ +R+ E + S +
Sbjct: 11795 KKLNDDKKMIEQEKEDLEKMKSEIMKQRQQMEEE-RSELENKIRQTYIEKCDIENSKEIV 11853
Query: 1502 MKAIREEELRKEK----------------DGKSALVENGEGCEAEKQGLEKT--VLERRA 1377
K + E E +K + D + L++N + E + ++ V+++
Sbjct: 11854 QKLMVEVEEQKHEIQFQKEELDIERQKIADEQDLLIQNKSELQNENERIKNINEVIKKER 11913
Query: 1376 SNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDL 1197
L M+A L KEK + ++TE + + + + + + + S D L+++
Sbjct: 11914 ETLKEMEAY----LEKEKEEMKSITEETRRQKEDLEKMSTHINEQKQDLRSQRDLLEQER 11969
Query: 1196 DRVMAEKQALEKRCSDLEA-----------KNASLTDNQEGHEAEIERKLEASNLTHNDE 1050
+ + + + L++R + +A K + ++++ E LE +E
Sbjct: 11970 EEINHKWKQLQQRIDEFDAQVSKQKEEDLPKEKEMKEDRKSLEETKANILEMKTKAEPEE 12029
Query: 1049 LHKEKDDKKSIMNDLDRVKAEKQVLESKVSDLETTYSTLNNELQQKMDDNEAFLNERDGL 870
+ KEK+ ++ +V+ E++ +E S LE S +++E ++ DD + E++ L
Sbjct: 12030 IKKEKEKEEEEQEMRVKVEMERKEIEQIKSQLERVRSEMDHEQKKLNDDKKMIEQEKEDL 12089
Query: 869 EAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKL 690
E +K + K+ +E +++ K K D + + + K+ + +L + + +
Sbjct: 12090 EKMKSEIMKQRQQMEEERSELDKKI-KQTDLEKHDIENSKEIVEKLMVEVEKQKHEIQFQ 12148
Query: 689 LKDINIWLSEVTELQEDLNKESKEKQDLEKRVLELTSKLEK 567
++++I ++ + Q+ L + E+Q+ +R+ E+ +++K
Sbjct: 12149 KEELDIERQKIADEQDLLIQNKIEQQNENERIKEMDEEIKK 12189
Score = 79.0 bits (193), Expect = 2e-11
Identities = 115/572 (20%), Positives = 246/572 (43%), Gaps = 91/572 (15%)
Frame = -3
Query: 2027 DELLNEKDDKKCIVND----RNILEAAKQALEYKVADLEAAKTTLND----------ELE 1890
+EL E+ D + D +N L+ K A E +ADL+ K+ L + ++E
Sbjct: 6378 EELKKERKDVAHLAEDTKREKNSLDEMKVANESSMADLQKEKSNLEEMKENISKQTEDIE 6437
Query: 1889 RKKD------DNNAIIKKALDKRISDLKADAPQRDQE--------DDMNALIXXXXXXXX 1752
++KD D ++ + K+ S+ + + ++E +D+ + I
Sbjct: 6438 KEKDKIRLREDELEQLQAEIHKQQSETEIEKSNIERERAAIIKDVEDLQSKIISLDRDAE 6497
Query: 1751 XXXXXXKIVSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSH----LES 1584
+ N + + + EL++E D+ + K + + ++ V E+ + + +
Sbjct: 6498 SLKLDREAFENEKEELKQMKTELEREADE---IEKIKLETQHERQRVEEMTADFMETMNN 6554
Query: 1583 KSRSL-KEHFLREEEDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQG 1407
+ + L K + EE+ + +E+ ++ + +E+L+ K K L E E K G
Sbjct: 6555 ERKQLDKNKVMIEEQKQEMEKKRDDMDQSRKSLDEDLKMMKAQKQVLEEEKNKLEQMKIG 6614
Query: 1406 LE---------KTVLERRASNLDTM-DAIHEE------ELRKEKVDKSALTENGEGCEAE 1275
LE K + NL+ M +A+ EE E++++ + E A+
Sbjct: 6615 LEREADEISKIKEETQNERQNLEKMANALKEEREYLAEEIKRKNQVLDKIKVANESTLAD 6674
Query: 1274 KQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAE 1095
Q ++ + ++ I + ++ + ++ + L+K ++++ + + + + E+E
Sbjct: 6675 LQKEKRILEEMRENISKQIEDIENEKEKSKLREDELKKLQTEVQKQQSEIDMEKTNIESE 6734
Query: 1094 IERKL-EASNLTHNDELHKEKDD----KKSIMNDLDRVKAEKQVLESKVSDLETTYSTLN 930
+ E N+ EL K+ +D K I+ + + + ++ +L+ V DL+ ++
Sbjct: 6735 RAAMIREKQNMM--TELKKKSEDVEMQMKEILTEKELLHNDRNLLKKDVEDLQQKLMSIE 6792
Query: 929 NELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLE----ATIHD---IEMKTGK------ 789
+ + D EAF NE++ ++ +K L+ + ++E T H+ +E KT +
Sbjct: 6793 RDSESLKLDKEAFENEKEAMKQMKTDLQIQADEIEKIKLETHHERQRVEEKTAQIQKERE 6852
Query: 788 ----------------DDDYNE--AEKQTLKKRISELEEAISILTDKAKKLLKDINIWLS 663
D+ Y E EK+ ++ S+LE+A S + K K+I I L+
Sbjct: 6853 EINTLVEEIKKKRDIIDESYTEIRKEKEAIESDRSDLEKAKS----QTFKQNKNIEIALA 6908
Query: 662 EVTELQEDLNKESKE------KQDLEKRVLEL 585
E+ + + L K SKE K + EK+ ++L
Sbjct: 6909 EIQQKRNALEKMSKEISRDRMKLEDEKKEIQL 6940
Score = 78.6 bits (192), Expect = 2e-11
Identities = 134/578 (23%), Positives = 246/578 (42%), Gaps = 76/578 (13%)
Frame = -3
Query: 2072 ESKVSVFEAAIATLNDELLNEKDD---KKCIVNDR-NILEAAKQALEYKVADLEAAKTTL 1905
+ K+ + EA + + ++ N +++ KKC + ++ E AK LE + D++ K
Sbjct: 9897 QEKLEISEADLKVMKEQCENAREETERKKCDIEEQIQNNENAKHLLEQERKDIDKQK--- 9953
Query: 1904 NDELERKKDD----------NNAIIKKALD--KRISDLKADAPQRDQEDDMNALIXXXXX 1761
EL+++ DD N + K++LD K++ + KA+ R ++D +
Sbjct: 9954 -QELQKQADDLDMRMIAHRENVEMSKRSLDEEKKLLEQKANEILRQRDD-----LEKEKE 10007
Query: 1760 XXXXXXXXXKIVSNLEVNILILHEELQKEKDDKTALI-KDLVAAEPGKRTVNEIVSHLES 1584
++ N N EE++ E D K I K+ E R +NE LE
Sbjct: 10008 DMMKKWNKLDVLQNEMQNENKAMEEIKYELDGKRNEINKEQQRLEESLRAINEEKGDLEI 10067
Query: 1583 KSRSLKEHFLREEEDEV--------LERSASNLAIMKAIREEELRKEKDGKSALVENGEG 1428
++ + EE V L++ S L K + E +K + ++ + +
Sbjct: 10068 MRADYEKQEQQIEEMRVEAKMERKELDQIKSELEKDKTEIDYEWKKLNNDRNMIEKERND 10127
Query: 1427 CEAEKQGL--EKTVLERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKT 1254
E K L ++ +E S LD I E K+K++K+ E E+Q +
Sbjct: 10128 LEKMKSELMTQRQQMEDERSELD--QKIKEANTEKDKIEKNKEIVERLMAEVEEQRNDFK 10185
Query: 1253 VLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEG--HEAEIERKL 1080
+ E + N ++ EK L + ++L+ K+ + + +E +E E ++
Sbjct: 10186 LKKEELALERQN---------IVDEKYLLAQCETELQNKSEQIRNMEEAVKNERETLKET 10236
Query: 1079 EASNLTHNDELHKEKDDKKSIMNDLDRVK-----------AEKQVLESKVSDLETTYSTL 933
EA L ++K + KSI+ + R K +KQ L++K LE +
Sbjct: 10237 EA-------HLQRDKKEIKSIIEETSRQKEDLEKISTGMNVQKQELKNKKDTLEQEREEI 10289
Query: 932 NN---ELQQKMDDNEAFLN---ERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNE 771
N+ + QQ++D+ +A + E D K E++ L+ E IEMKT + +++E
Sbjct: 10290 NHKWTQFQQRIDEFDAQVRKQKEEDLTNQKKMEEERKCLE-EVNGKIIEMKTKAELEHHE 10348
Query: 770 A-----EKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEV----TEL---------- 648
E QTL+++I + +E +T K K +D++ SE+ TE+
Sbjct: 10349 INQKIEELQTLQEQIMKEKEKAEAMTIKLKMEREDLDQIKSELVREKTEVDHEQKKLNDD 10408
Query: 647 -------QEDLNKESKE----KQDLEKRVLELTSKLEK 567
+EDL K E KQ++EK EL +K+++
Sbjct: 10409 IKMIEQEKEDLEKMKSEIMTQKQEMEKERSELDNKIQQ 10446
Score = 77.0 bits (188), Expect = 6e-11
Identities = 108/541 (19%), Positives = 221/541 (40%), Gaps = 58/541 (10%)
Frame = -3
Query: 2042 IATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAI 1863
IA + D+LL EK+D +E K+ + + +E ++ LND+ E +N +
Sbjct: 13332 IADMKDQLLKEKED----------VETTKERINREKEHIEKMQSQLNDQKEEMDLENQKL 13381
Query: 1862 I---------KKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEV 1710
+ AL+K + DL+ + +++NAL+ E
Sbjct: 13382 LYMKTEIQVKTNALEKMMQDLQKE------RENVNALVIQHQ-------------KEREQ 13422
Query: 1709 NILILHEELQKEKDDKTALIKDLVAAEPGK-------RTVNEIVSHLESKSRSLKEHFLR 1551
+++ E +KEK + + + E K ++++ S L+++S L E+ ++
Sbjct: 13423 RDILIEENKRKEKHAEAEIQRQFEDIESVKVRLVTESNQIDKMNSELKTRSEEL-ENLIK 13481
Query: 1550 EEEDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASN 1371
+++ E + KA+ E++ E + KS ++N + EK + + L++ +
Sbjct: 13482 KQQKEFETKENEMQRERKAL--EKMNAELERKSTELKN----KIEKVTVWEADLQKEKNK 13535
Query: 1370 LDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDR 1191
+ + I E E + +K+ + + E ++ + + +LE L D + L R
Sbjct: 13536 TEELKNILEREKSELYQEKAQVQQQKHEMETIRKTMKSEMENLECLRNELEDEKKSMLSR 13595
Query: 1190 VMAEKQALEKRCSDLEAKNAS----------LTDNQEGHEAEIERKLEASNLTHNDELHK 1041
+ EK ++K ++++++ S L D E +++ +E N+ + +
Sbjct: 13596 LSMEKHEIDKLKTEIQSEKESIEEEKKTLKQLKDENESKRTQLDNTIEKMNMDKLS-IQR 13654
Query: 1040 EKDDKKSIMNDLDRVKAEK-----------------------------QVLESKVSDLET 948
EKD + I DL R KAEK + L S +D+E
Sbjct: 13655 EKDSLEEIKADLQR-KAEKLDEEMRKAVQITSQISQDAKILDDDREKEEELRSMRADIER 13713
Query: 947 TYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEA 768
L +++Q L+ K+ LEK + + D+E K N+
Sbjct: 13714 QAKILESDVQL--------------LQTEKEILEKSKTENDLLREDLE----KQRKRNDL 13755
Query: 767 EKQTLKKRISELEEAISILT---DKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKR 597
Q L+K LE+ I+ +T D L ++++ E+ + +L+++ KE DL +
Sbjct: 13756 TLQELRKEKMALEQMITDITKEKDAVASLQNEVSLKQHELKNKETELDEQRKEMDDLRMQ 13815
Query: 596 V 594
+
Sbjct: 13816 L 13816
Score = 75.5 bits (184), Expect = 2e-10
Identities = 117/561 (20%), Positives = 241/561 (42%), Gaps = 56/561 (9%)
Frame = -3
Query: 2081 QALESKVSVFEAAIATLNDELLNEK----DDKKCIVNDRNILEAAKQALEYKVADLEAAK 1914
Q + ++ + IA D L+ K ++ + I N +++ ++ L+ A LE K
Sbjct: 10476 QLQKEELDIERQKIADEQDLLIQNKSELQNENERIRNINEVIKKERETLKEMEAHLEKEK 10535
Query: 1913 T---TLNDELERKKDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXX 1743
++ +E R+K+D L+K +D+K ++ D+ L
Sbjct: 10536 EEMKSITEETRRQKED--------LEKMSTDIKEQNQDLMKQRDL--LEQEKEDINHEWT 10585
Query: 1742 XXXKIVSNLEVNILILHEE---LQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRS 1572
+ + + + EE QKE ++ +++ A +T E+ + K +
Sbjct: 10586 QLQQRIDEFDAQVSKQKEEDLTKQKEMKEERKSLEETKARIIEMKTKAELEDIKKEKEKE 10645
Query: 1571 LKEHFLR---EEEDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLE 1401
+E +R E + + L+R S L ++ + E +K D K + E EKQ LE
Sbjct: 10646 EEEEEMRVKVEMDGKELDRIKSELKRERSEIDHEQKKLNDDKKII-------EQEKQNLE 10698
Query: 1400 KTVLERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPT---I 1230
K ++ + + EE E K E + E K+ +K ++++E I
Sbjct: 10699 KM----KSEIMKQRQQMEEERSELENKIKQTYIEKCD-IENSKEIVQKLMVEVEEQKHEI 10753
Query: 1229 PSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQE--GHEAEIERKLEASNLTHN 1056
+ L + ++ E+ L + S+L+ +N + + E E E +++EA
Sbjct: 10754 QFQKEELDIERQKIADEQDLLIQNKSELQNENERIRNLNEIIKKERETLKEMEA------ 10807
Query: 1055 DELHKEKDDKKSIMNDLDRVKAEKQVLESKVSD-----------LETTYSTLNN---ELQ 918
L K+K++ KS+ + R+K + + + + V+ LE +N+ +LQ
Sbjct: 10808 -HLEKKKEEIKSVSEETRRLKEDLEKMSTDVNKQNKDLMNQRDLLEQEREEINHKWKQLQ 10866
Query: 917 QKMDDNEAFLNERDGLEAVKQ-GLEKRVLDLEAT-IHDIEMKTGKDDDYNEAEKQTLKKR 744
Q++D+ +A ++++ + K+ G+++ LE T + IEMKT + + + EK+ +
Sbjct: 10867 QRIDEFDAQVSKQKEQDLPKEKGMKEDRKSLEETKANVIEMKTKAEPEEIKKEKEKENEE 10926
Query: 743 ISELEEAISILTDKAKKLL------------------KDINIWLSEVTELQEDLNKES-- 624
E EE I ++ + +K L K +N ++ + + +EDL K
Sbjct: 10927 EEEEEEEIRVIVETERKELYQIKSELERVRSEIDHEQKKLNDYMKMIEQEKEDLEKMKSE 10986
Query: 623 --KEKQDLEKRVLELTSKLEK 567
K++Q +E+ EL +K+++
Sbjct: 10987 IMKQRQQMEEERSELDNKIQQ 11007
Score = 75.1 bits (183), Expect = 2e-10
Identities = 111/513 (21%), Positives = 212/513 (41%), Gaps = 67/513 (13%)
Frame = -3
Query: 1904 NDELERKKDD-NNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKI 1728
ND +E+ ++D NNA+ K +D+ D++ QE A++ I
Sbjct: 1457 NDRVEQMREDVNNAL--KDIDQAKEDIQRQREVIAQEKVQPAIVATKSSEYAKTEEPGAI 1514
Query: 1727 VSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLRE 1548
S + L L +QKE+ + K+++ E K +N+I +++ +E ++
Sbjct: 1515 KS-YRASDLELSASIQKERQELEHY-KEIILKE--KHELNKIKEDVKAVKNDAEERMIKL 1570
Query: 1547 EEDEVLERSASNLAIMKAIREEELRKEKD--GKSALVENGEGCEAEKQGL---------E 1401
E+E E +++ R+ + KEK+ G A+ + KQ L E
Sbjct: 1571 HEEEK-EMKTKRVSLQNWERQLQTEKEKNQKGLDAIWNENQQLNERKQQLDIKELHLQSE 1629
Query: 1400 KTVLERR-------------------ASNLDTMDAIHEEELRKEKVDKSALTENGEGCEA 1278
K+ LE + AS D +I E + +++ ++ + C
Sbjct: 1630 KSKLEYKKPLEIKQVDAQVQTELMEDASEYDMALSIEELDKQRQFLEYFKQELLAQKCTM 1689
Query: 1277 EKQGPE-------------------KTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRC 1155
E+Q E +T D+E + L++ D + K ++K
Sbjct: 1690 ERQMAEIELSRDELSLREATLQTATQTTADMELQLELQKQELEQTKDEMERTKLEVQKGW 1749
Query: 1154 SDLEAKNASLTDNQEGHEAEIERKLEASNLTHND-ELHK---EKDDKKSIMNDLDRVKAE 987
DL+ + A + +E E+E+ + N D E K E D K ++ + + ++A+
Sbjct: 1750 VDLQTQIAESREKEEMVRIELEKARDVLNRIRQDVETEKQTMEADLKFTLAKEFENLEAQ 1809
Query: 986 KQVLESKVSDLETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDI 807
++++E + LE L E +ER +E + L++ +LE HD+
Sbjct: 1810 RKMMEDEKRALENMKYELQRESGYIERSKHNMHDERQNMENWAEKLKQEWEELEKKRHDM 1869
Query: 806 EM------KTGKD-DDYNEAEKQTLK--KRISELEEAISILTDKAKKLLKD----INIWL 666
+ + KD ++ E + TL K S++ E IS L + K +++ I I
Sbjct: 1870 QQLQTERSREIKDLENLRELNELTLNQIKTKSDVLEKISELNSQQKDEIENEKSKIKIRE 1929
Query: 665 SEVTELQEDLNKESKEKQDLEKRVLELTSKLEK 567
++ ++Q DLN++ KE QD++ V S+L+K
Sbjct: 1930 YDLQQMQTDLNRQQKEMQDIQNAVFMEKSELKK 1962
Score = 73.9 bits (180), Expect = 5e-10
Identities = 114/552 (20%), Positives = 236/552 (42%), Gaps = 49/552 (8%)
Frame = -3
Query: 2075 LESKVSVFEAAIATLNDELLNEKDDKKC----IVNDRNILEAAKQALEYKVADL------ 1926
L+ V+ A L ++LL E++ K I ++++L KQ + + D+
Sbjct: 3289 LKKTVTDIAGAKEDLENQLLEEREKNKVKQAEIQAEKDMLYLLKQGISEQQVDIVNKTEQ 3348
Query: 1925 ----EAAKTTLNDELERKKDDNNAIIKKALDK--RISDLKADAPQRDQEDDMNALIXXXX 1764
E L + R++D+ A K +++ R+ K + + +E +
Sbjct: 3349 LRLREVELEQLQALIYRQQDEIEANRKAIINEKYRLEGQKTEIDRLQREVNQMMEYASKD 3408
Query: 1763 XXXXXXXXXXKIVSNLEVNILILHEELQKEK---DDKTALIKDLVAAEPGKRTVNEIVSH 1593
I +++I EL KE+ +++T ++ KRT E+
Sbjct: 3409 RANLEKEKSEMIAQKHQMDI-----ELNKERGLIEERTQMLNTYEKEMDQKRTALEV--- 3460
Query: 1592 LESKSRSLKEHFLREEEDEV------LERSASNLAIMKAIREEELRKEKDGKSALVENGE 1431
E K + ++EE++++ L+R A ++ +K E+ R E+ + EN
Sbjct: 3461 -EMKELKYHKQAIQEEKNKLQQMKIELQREADDIKKLK----EKTRNERQSLEKMAEN-- 3513
Query: 1430 GCEAEKQGLEKTVLERRASNLDTMDAIHEE---ELRKEKVDKSALTEN----GEGCEAEK 1272
E EK L + + + D M +HE +++KEK + + E+ E ++EK
Sbjct: 3514 -LEKEKDDLAHLAEDTKRKD-DEMKVLHESALADIQKEKCNLEQMRESMFKQNEMIDSEK 3571
Query: 1271 QGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEI 1092
+ K +L D LQ+ + ++ ++ + S +E + A++T + E+
Sbjct: 3572 K---KMILR--------EDKLQQMQAEINRQQTEMDTKKSIIENERAAMTKKNQDLMTEL 3620
Query: 1091 ERKLEASNLTHNDELHKEK---DDKKSIMNDLDRVKAEKQVLESKVSDLETTYSTLNNE- 924
++ E + + L +++ D+K + D++ ++ + ++ES L+ L NE
Sbjct: 3621 TKQSEDVEIQMKEVLTEKELLESDRKLLKKDVENLQQKLLIIESDSESLKQDRELLENEK 3680
Query: 923 --LQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLK 750
L+Q D + E + ++ Q +RV ++ A I K + + L
Sbjct: 3681 EVLKQMKTDLQGEAEEIEKIKLETQHERQRVEEMTAQIQKERDKINNLIEETNRKDMVLN 3740
Query: 749 KRISELEEAI-SILTDK--AKKLLKDINIWLSEVTELQEDLNKE--------SKEKQDLE 603
++ ++EE I SI +DK +K ++ SE+ +++EDL K+ KE++DLE
Sbjct: 3741 EKNRDIEEKIKSIQSDKDMLEKEKHNLEKTRSELYKVKEDLEKQKENTLAEIQKEREDLE 3800
Query: 602 KRVLELTSKLEK 567
K +T ++ +
Sbjct: 3801 KMNENITIEMHE 3812
Score = 73.6 bits (179), Expect = 7e-10
Identities = 118/540 (21%), Positives = 235/540 (43%), Gaps = 37/540 (6%)
Frame = -3
Query: 2075 LESKVSVFEAAIATLN-DELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLND 1899
LE + FE A ++ E L E+ +K+ I D+ + ++ E + L K N+
Sbjct: 2743 LEKERDCFEKEKADISLREELEEQSEKEGI--DKTRVRIKQEMDELEQTRLNVVKELENN 2800
Query: 1898 ELERK--KDDNNAI--IKKALDKRISDLKADAPQRDQEDDMN---ALIXXXXXXXXXXXX 1740
EL+++ +D+ + I IK L K D + ++D E+D ++
Sbjct: 2801 ELQKQIIEDERDKIEQIKAELQKEAKD--TEKQRQDIENDRRNNEEMVIKLQNEKKDIET 2858
Query: 1739 XXKIVSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEH 1560
+ + E N+ +L + L+ ++D L K+ + + ++ LES++R +
Sbjct: 2859 STDRIRDEEANLRVLKQRLESDRD---TLEKERFDLKKTNTEMKDLEKQLESQNRQHEIQ 2915
Query: 1559 FLR-EEEDEVLERSASNLAIMKAIREEE---LRKEKDGKSALVENGEGCEAEKQGLEKTV 1392
++E E+LE+ L+ K E+E KEK S E E ++E++G+ KT
Sbjct: 2916 LAEIQKEREILEQLKLTLSKQKEDLEKERDCFEKEKADISLREELQE--QSEREGIGKT- 2972
Query: 1391 LERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDA 1212
R MD EL++ +++ EN E +KQ
Sbjct: 2973 ---RVRIKKEMD-----ELKQTRLNVVKELENNE---LQKQ------------------I 3003
Query: 1211 LQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASNLTHNDELHKEKD 1032
++ + D++ K L+K D E + + ++ +E E+ KL+ + +D
Sbjct: 3004 IEDERDKIEQIKAELQKEAEDTEKQRRDIEKDRRNNE-EMVIKLQNEKKDIETSTDRIRD 3062
Query: 1031 DKKSIMNDLDRVKAEKQVLESKVSDLETTYSTLNN---ELQQKMDDNEAFL----NERDG 873
++ ++ R+++++ LE + DLE T + + N +L+ ++ +E L ER+
Sbjct: 3063 EEANLEVQKQRLESDRDTLEKERFDLEKTKTEMGNLKKQLESQIRQHEIQLVEIQKEREI 3122
Query: 872 LEAVKQGLEKRVLDLEATIHDIEMKTG----KDDDYNEAEKQ-------TLKKRISELEE 726
LE +K L K+ DLE E + +D ++E++ +K+ + ELE+
Sbjct: 3123 LEQLKINLSKQKEDLEKERDCFEKEKADISLSEDLKEQSEREGIDNTRTRIKQEMDELEK 3182
Query: 725 AISIL------TDKAKKLLKDINIWLSEV-TELQEDLNKESKEKQDLEKRVLELTSKLEK 567
L + KK+++D + ++ EL+++ K E Q+ + + E +KL+K
Sbjct: 3183 TRQNLAKEQENNELQKKIIEDERDKIEQIKAELKKEAEKTKLELQNERQNLEEAGTKLKK 3242
Score = 73.2 bits (178), Expect = 9e-10
Identities = 128/570 (22%), Positives = 246/570 (43%), Gaps = 69/570 (12%)
Frame = -3
Query: 2072 ESKVSVFEAAIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDEL 1893
+ ++ + I L EL EK+ I+ DR+ L+ + ++L+ +T +ND +
Sbjct: 3824 QDELDQLKTEIQNLQQELEKEKE---IIMKDRS-------ELDLRQSELDKQQTNMNDII 3873
Query: 1892 ERKKDDNNAIIKKALDKRISDLKADAPQRDQE-DDMNALIXXXXXXXXXXXXXXKIVSNL 1716
E K++ +K LDK +++ + ++E D+M+ I +++
Sbjct: 3874 ETMKNE-----RKLLDKDKEEMEEQKQEMEKERDNMDQSIKSLDEDLKMMKLQKQVIEEE 3928
Query: 1715 EVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRS----LKEHFLRE 1548
+ + + ELQ+E D+ I+ + +R E ++ K R L E+ RE
Sbjct: 3929 KNKLEQMKFELQREADE----IRKIKEETQNERQSLEKMTKALIKEREDLVHLAEYTKRE 3984
Query: 1547 EE--DEVLERSASNLA-------IMKAIRE------EELRKEKDGKSALVENGEG---CE 1422
+E DE+ + S++A I++ +RE E++ EK+ KS L E+ E
Sbjct: 3985 KEMLDEMQVANKSSMADLQREKRILEEMRENISKQTEDIENEKE-KSKLREDELKKLQTE 4043
Query: 1421 AEKQ----GLEKTVLERRASNLDTMDAIHEEELRKEKVD-----KSALTENGEGCEAEKQ 1269
+KQ +EKT +E + + EL+K+ D K LTE E E +
Sbjct: 4044 VQKQQSEIDMEKTNIESERAVMIREKQNMMTELKKKSEDVEIQMKEILTEK-ELLENDSN 4102
Query: 1268 GPEKTVLDLEPTIPSL---NDALQRDLDRVMAEKQALEKRCSDLE--AKNASLTDNQEGH 1104
+K + DL+ + S+ +++L+ D + EK+ L++ +DL+ A + H
Sbjct: 4103 LLKKDMEDLKQKLMSIERDSESLKLDREAFGNEKEVLKQMKTDLQIQADEIEKIKLETQH 4162
Query: 1103 EAEIERKLEASNLTHNDELHK---EKDDKKSIMNDLDR--------VKAEKQVLESKVSD 957
+ + + A DE++ E + K ++N++DR ++++K +LE + +
Sbjct: 4163 DRQRVEEKTAQIQKDRDEINNLIVETNRKDMVLNEMDRDIEEKIKSIQSDKDMLEKERHN 4222
Query: 956 LETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDY 777
LE T S L + E ER +E +K+ + + + +++ H E K D+
Sbjct: 4223 LEKTRSELARAKENLETQREI---ERKDIEKMKKNISREMHEIK---HQEEQMKQKQDEL 4276
Query: 776 N-------------EAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLS--------E 660
+ E EK+ + K S+L+ S L DK + + DI + +
Sbjct: 4277 DQLKTEIQNLQQELEKEKEIIMKARSQLDLRQSEL-DKQQTNMNDIMETMKNERKQLDKD 4335
Query: 659 VTELQEDLNKESKEKQDLEKRVLELTSKLE 570
E +E + KEK D ++ L L+
Sbjct: 4336 KEETEEQKQEMEKEKHDFDQSRKSLDEDLK 4365
Score = 73.2 bits (178), Expect = 9e-10
Identities = 101/486 (20%), Positives = 210/486 (43%), Gaps = 13/486 (2%)
Frame = -3
Query: 2036 TLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIK 1857
TL + N + I N+ L + + L D+ L + E + N +++
Sbjct: 7161 TLEEMRANISKQVETITNENKSLSSRESELAKLQEDI------LQQQQEMDELKNTIMME 7214
Query: 1856 KA-LDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQ 1680
LD+R SD+ D Q++ +D M+ ++N+E L + + +
Sbjct: 7215 MCQLDQRQSDI--DLLQKEVDDLMD--------------FTKTEMANVERERLEVLAQTR 7258
Query: 1679 KEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEV-LERSASNLAI 1503
K D +L + A E + +NE +E + L ++ ++D++ ++R NL +
Sbjct: 7259 NIKSDMVSLKMEKEACEQLRLKLNEEKDLIEKERELLTKNLDHTDKDKMDMKRELENLKV 7318
Query: 1502 MKAIREEELRKEKDGKSALVENGEGCE--AEKQGLEKTVLERRASN----LDTMDAIHEE 1341
K + E ++ + K +L G + +EK E+ ++E A+ LD + E
Sbjct: 7319 EKETIKNEKKELEKMKISLQRKAIGFKEFSEKTKDERPIVEEMAAQFTRQLDISERPAEG 7378
Query: 1340 ELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEK 1161
+ +E++D++ + EKT DL+ T +N D + + ++ L K
Sbjct: 7379 KFIEERLDQTEKKRRKTYYTEDLFQEEKT--DLQKTKEEIN----YDREEIYRQRTELNK 7432
Query: 1160 RCSDLEAKNASLTDNQEGHEAEIERKLEASNLTHNDELHKEKDDKKSIMNDLDRVKAEKQ 981
E E +++ SNL + + KEK+ + N+LD+++AE
Sbjct: 7433 -------------------EKETLKQMHTSNLKEIENIEKEKEKIQRTWNELDQIRAE-- 7471
Query: 980 VLESKVSDLETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEM 801
L++K D++ T + + E + D E NE+D L+ ++ ++K + +L+ E
Sbjct: 7472 -LQNKQRDMDDTTNIMMKEKAELARDLENLQNEKDELQKSRENIQKLMKELQ------EE 7524
Query: 800 KTGKDDDYNEAEKQ---TLKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQ--EDL 636
+ + N+ +Q +K + L+E + + + + L+ D I ++ +LQ +D+
Sbjct: 7525 RLKTSEALNKERQQFTEEIKLKNDSLDEIQAEIDRQKRALVTDKEIITKQMMDLQKTQDV 7584
Query: 635 NKESKE 618
++S E
Sbjct: 7585 RRQSDE 7590
Score = 72.8 bits (177), Expect = 1e-09
Identities = 109/496 (21%), Positives = 222/496 (44%), Gaps = 26/496 (5%)
Frame = -3
Query: 1994 CIVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAI-IKKALDKRISDLKAD 1818
C+ D L+ ++A E + L+ KT ELER+ D+ I ++ D++ + A
Sbjct: 5201 CLDRDAESLKLDREAFENEKEVLKQMKT----ELEREADEIEKIKLETQHDRQRVEEMAA 5256
Query: 1817 APQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDKTALIKDLV 1638
Q+D+ D++N LI L + E+++ + DK L K+
Sbjct: 5257 QIQKDR-DEINNLIEETNRKDMV----------LNEKNRDIEEKIKSIQSDKDMLEKEKH 5305
Query: 1637 AAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNLAI-MKAIR--EEELRKE 1467
E + + ++ LE + + +E ED LE+ N+ M I+ EE++ ++
Sbjct: 5306 DLEKTRSELYKVKEDLEKQKENTLAEIQKERED--LEKMNENITREMHEIKHQEEQMNQK 5363
Query: 1466 KDG----KSALVENGEGCEAEKQGL--EKTVLERRASNLDTMDAIHEEELRKEKVDKSAL 1305
+D K+ + + E EK+ + +++ L+ R S LD + + K ++ L
Sbjct: 5364 QDELDQLKTEIQNLQQELEKEKEIIMKDRSQLDLRQSELDKQQTNMNDIMETMKNERKQL 5423
Query: 1304 TENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASL 1125
++ E E +KQ EK +++ + SL++ D ++ +KQ E+ + LE L
Sbjct: 5424 DKDKEEMEEQKQEMEKERDNMDQSRKSLDE----DQKKMKLQKQMFEEEKNKLEQMKIEL 5479
Query: 1124 TDNQEGHEAEIERKLEASNLTHNDELHKEKDD----KKSIMNDLDRVKAEKQVL------ 975
EA+ K++ L K ++ K+S+ + + K EK++L
Sbjct: 5480 E-----READEISKIKEETQNKRQRLEKMTEELIREKESLAHLAEDTKTEKKILDEMKVA 5534
Query: 974 -ESKVSDLETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMK 798
ES ++DL+ S L ++M +N + L E E K L E + ++ +
Sbjct: 5535 NESSMADLQREKSIL-----EEMRENISKLKEYIDNEKEKSKLR------EDELKKLQTE 5583
Query: 797 TGKDDDYNEAEKQTLK-KRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESK 621
K + EK ++ +R + + E +++T+ KK +D+ I + E+ +E L+ + K
Sbjct: 5584 VQKQQSKIDMEKTNIESERAAMIREKQNMMTE-LKKKSEDVEIQMKEILTEKELLHNDRK 5642
Query: 620 ----EKQDLEKRVLEL 585
+ ++L++++++L
Sbjct: 5643 LLTRDVENLQQKLIDL 5658
Score = 72.4 bits (176), Expect = 2e-09
Identities = 119/603 (19%), Positives = 247/603 (40%), Gaps = 64/603 (10%)
Frame = -3
Query: 2042 IATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAI 1863
+ L E+ ++ K ++++ I ++ Q L + + L E+E K D
Sbjct: 8729 VRNLKGEMERRMEESKVEIDEKEIFKSEIQRLIQDIGQIRENLGGLKTEIENTKRD---- 8784
Query: 1862 IKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEEL 1683
K L+K ++L + Q+++E L + ++E++ ++ E+
Sbjct: 8785 -KSNLEKMKAEL--EEKQQEEESMREILQKEKEELEQLKKDINREKEDIEISRELVESEI 8841
Query: 1682 -----------QKEKDDKTALIKDLVAAEPGKRTVNEIVSHLES----------KSRSLK 1566
QK K++ + ++L+ + +N V HL K ++
Sbjct: 8842 YEGEVKGFTDVQKYKEELQIVTEELLTKKRNLEQLNSDVQHLMQTLEEVDIQYIKKKAEL 8901
Query: 1565 EHFLRE--EEDEVLERSASNL--------------AIMKAIREEELRKEKDGKSALVENG 1434
EH E + +++LE+ L +++I E L+K +D + +
Sbjct: 8902 EHITSEIQKREQILEKQKKKLEENGWIIEEIEMMKVTLESINMEILQKRED----MEKEK 8957
Query: 1433 EGCEAEKQGLE--KTVLERRASNLDT--MDAIHEEELRKEKVDKSALTENGEGCEAEKQG 1266
E EKQ E + L+R+ +++ I E++ K K+D E E E +
Sbjct: 8958 ENLRREKQETELFRGELQRQRDEVESSRQALIMEKDQFKLKIDHQR-NEMSAAFEKEHKR 9016
Query: 1265 PEKTVLDLE----PTIPSLNDA------LQRDLDRVMAEKQALEKRCSDLEAKNASLTDN 1116
E DLE SLNDA LQ+ + + EK+ +E+ ++ + +
Sbjct: 9017 LENMENDLENQRAKLAESLNDAAKMEQKLQQMKNELNKEKEQVEEMKQMVKTERVKIEQE 9076
Query: 1115 QE-----------GHEAEIERKLEASNLTHNDELHKEKDDKKSIMNDLD-RVKAEKQVLE 972
+E GHE ++++K E + D+L ++ + + + DL +++ ++Q +E
Sbjct: 9077 KEEMRKQTQEIEDGHE-KLQKKTEIA-----DKLLQDANSESDRLKDLSMKLQMQRQDIE 9130
Query: 971 SKVSDLETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTG 792
+++ET +L+ ++ DD N+RD E LE + +L D+E K
Sbjct: 9131 KTNTEMETKKRSLDRMSRELQDDKIRLKNDRDAYEKDMTHLELKREELVRETEDLERKIL 9190
Query: 791 KDDDYNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQ 612
+ + +E K+ ++ + LE + K + K++ SE +L ++
Sbjct: 9191 QQREQDEMAKRDIENQTEALEVMKVDILKKRNEFAKEMENVHSERQKLLLLQGALQSQES 9250
Query: 611 DLEKRV-LELTSKLEKCICGARDGLSTIKEAWMSDCMVPDNWVPFEDLVQGFSRKTSPLD 435
+LE RV +E L++ + + E MS+ + + + L++ R+ L+
Sbjct: 9251 ELENRVFMEEQKHLKQAKAETEECRKQLAE--MSETVTTEQ-NEYRKLIEELQREKEQLE 9307
Query: 434 ITK 426
I+K
Sbjct: 9308 ISK 9310
Score = 71.6 bits (174), Expect = 3e-09
Identities = 103/494 (20%), Positives = 209/494 (42%), Gaps = 8/494 (1%)
Frame = -3
Query: 2042 IATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLND---ELERKKDDN 1872
I ++ +E +K+D + I N+ KQ L+ K LE + +N + +++ D+
Sbjct: 10247 IKSIIEETSRQKEDLEKISTGMNV---QKQELKNKKDTLEQEREEINHKWTQFQQRIDEF 10303
Query: 1871 NAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILH 1692
+A ++K ++ +++ K +R +++N I ++ + H
Sbjct: 10304 DAQVRKQKEEDLTNQKKMEEERKCLEEVNGKII-----------------EMKTKAELEH 10346
Query: 1691 EELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASN 1512
E+ ++ I++L +T+ E + + K+ ++ E ED L++ S
Sbjct: 10347 HEINQK-------IEEL-------QTLQEQIMKEKEKAEAMTIKLKMERED--LDQIKSE 10390
Query: 1511 LAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGL--EKTVLERRASNLDTMDAIHEEE 1338
L K + E +K D + + E E K + +K +E+ S LD + I + +
Sbjct: 10391 LVREKTEVDHEQKKLNDDIKMIEQEKEDLEKMKSEIMTQKQEMEKERSELD--NKIQQTD 10448
Query: 1337 LRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKR 1158
L K ++KS E E+Q E I + L + ++ E+ L +
Sbjct: 10449 LEKHDIEKSKEIVEKLMFEVEEQRHE---------IQLQKEELDIERQKIADEQDLLIQN 10499
Query: 1157 CSDLEAKNASLTDNQE--GHEAEIERKLEASNLTHNDELHKEKDDKKSIMNDLDRVKAEK 984
S+L+ +N + + E E E +++EA L KEK++ KSI + R +K
Sbjct: 10500 KSELQNENERIRNINEVIKKERETLKEMEA-------HLEKEKEEMKSITEETRR---QK 10549
Query: 983 QVLESKVSDLETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIE 804
+ LE +D++ + N+ + +RD LE K+ + L+ I + +
Sbjct: 10550 EDLEKMSTDIK--------------EQNQDLMKQRDLLEQEKEDINHEWTQLQQRIDEFD 10595
Query: 803 MKTGKDDDYNEAEKQTLKKRISELEEA-ISILTDKAKKLLKDINIWLSEVTELQEDLNKE 627
+ K + + +++ +K+ LEE I+ K K L+DI + E +E K
Sbjct: 10596 AQVSKQKEEDLTKQKEMKEERKSLEETKARIIEMKTKAELEDIKKEKEKEEEEEEMRVKV 10655
Query: 626 SKEKQDLEKRVLEL 585
+ ++L++ EL
Sbjct: 10656 EMDGKELDRIKSEL 10669
Score = 71.6 bits (174), Expect = 3e-09
Identities = 112/532 (21%), Positives = 220/532 (41%), Gaps = 62/532 (11%)
Frame = -3
Query: 1982 DRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKAL--------DKRISDL 1827
D+ ++ K +LE ADL+ L++E+ + + I + A ++ + +
Sbjct: 13648 DKLSIQREKDSLEEIKADLQRKAEKLDEEMRKAVQITSQISQDAKILDDDREKEEELRSM 13707
Query: 1826 KADAPQRDQ--EDDMNALIXXXXXXXXXXXXXXKIVSNLEV----NILILHEELQKEKDD 1665
+AD ++ + E D+ L + +LE N L L +EL+KEK
Sbjct: 13708 RADIERQAKILESDVQLLQTEKEILEKSKTENDLLREDLEKQRKRNDLTL-QELRKEKMA 13766
Query: 1664 KTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVLE--RSASNLAIMKAI 1491
+I D+ + + V+ L+++ SLK+H L+ +E E+ E + +L + +
Sbjct: 13767 LEQMITDITKEK-------DAVASLQNEV-SLKQHELKNKETELDEQRKEMDDLRMQLEM 13818
Query: 1490 REEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTM---------------D 1356
R+ K++ + + + ++ + E R D + D
Sbjct: 13819 RQNSTNKQQQEVDVFIVENMKMRNDLESMKTLLDEERRQLQDNIKTFEDQKNVLHPSKTD 13878
Query: 1355 AIHE-EELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLN---DALQRDLDRV 1188
A+ + +EL K D E+ E E K ++ + + SLN + ++++
Sbjct: 13879 AVQQTDELEKFTTDIKTEKEHVEKEREEIDVLNKEIIKSKEELQSLNLEIEMFKQEIAGK 13938
Query: 1187 MAEKQALEKRCSDLEA------------KNASLTDNQEGHEAEIERKL-----EASNLTH 1059
A+ ++LE+ +DL A K ++ D ++ E E++ L E L +
Sbjct: 13939 RAQIESLEQLRADLLAGADDIKTLVQTEKQMAIEDTEKKTEVELQMNLQKQKNELEELRN 13998
Query: 1058 NDELHKEKDDKKSIMNDLDR---------VKAEKQVLESKVSDLETTYSTLNNELQQKMD 906
E K + + + IM D + +K+E+ VLE + S+L LN ++Q++ +
Sbjct: 13999 TIEAEKHQVENRKIMLDKQQKEVEDIMTVIKSERDVLEKEKSELNKLSHVLNEKVQREQE 14058
Query: 905 DNEAFLN-ERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELE 729
+ E L ERD +E K+ +E +EKQ++++ +EL
Sbjct: 14059 ELERLLEKERDDIENCKKIIE-------------------------SEKQSIERERAEL- 14092
Query: 728 EAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLELTSKL 573
K+L +++ + E T LQ+D N KEK+ LE T ++
Sbjct: 14093 ----------KRLKEEVEVQ-HERTLLQQDKNMIQKEKEHLEGEKARTTEEI 14133
Score = 70.1 bits (170), Expect = 7e-09
Identities = 113/520 (21%), Positives = 220/520 (42%), Gaps = 45/520 (8%)
Frame = -3
Query: 2018 LNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKA---L 1848
L EK+ + + D L ++ L+ A + K + E +KD+ AI++K +
Sbjct: 12824 LQEKNVQMGTILDE--LNKRQEELDAIKAKTQREKEQMGHTEELEKDELIAILQKREEIV 12881
Query: 1847 DKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILI-LHEELQKEK 1671
+ + +++ + +E D + +++ N E + L + L+K+K
Sbjct: 12882 KRHMEEIQNQREELQKEKDQFGNMQAELQKGQLEMEMHQLMLNSERDELNGMRVNLEKQK 12941
Query: 1670 DDKTALIKDLVAAEPG---------KRTVNEIVSHLESKSRSLK----EHFLREEEDEVL 1530
++ + ++L + P K+ V E+ + L + + E R E+ + +
Sbjct: 12942 EEFELMQQNLESRRPESLLEDILKEKKRVEEMAAQLSKEQEEFRNIMSETIKRMEKIKQI 13001
Query: 1529 ERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAI 1350
E I A EE +KE D + + E CE ++ + + L + + +D
Sbjct: 13002 EGEIKTKQIEMACLEELKQKELDEQKNMRE----CENQELQMRREELAKMKTEID----- 13052
Query: 1349 HEEELRKEKVDKSALTENGEGCEAE-------KQGPEKTVLDLEPTIPSLNDALQRDLDR 1191
+ ++++ K E CE E K+ PEK +++ +D + +D
Sbjct: 13053 ----IERDEIQKLRKQYEKEKCELEQIKPDLQKREPEKIDAEVQ------HDEIHGGIDS 13102
Query: 1190 VMAEKQALEKRCSDLEAKNASLT----------DNQEGHEAEIERKLEASNLTHNDELHK 1041
+ E++ +EK +DL+ K D E EAEIE+ A ND
Sbjct: 13103 LKEEREEIEKMKADLQNKLREAENMRDIMKREKDELEKKEAEIEQM--AVETEDNDSDKN 13160
Query: 1040 EKDDKKSIMNDLDRVKAEKQVLES-------KVSDLETTYSTLNNE---LQQKMDDNEAF 891
+D+ I L K +K LE + ++LET L E L +K+ + E F
Sbjct: 13161 LQDEMMKIEAILKVTKKQKNYLEQMNENLTREKTELETNCQMLEREKTELNKKVKETEEF 13220
Query: 890 -LNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISI 714
+++ + EA ++ +E RV+D A H+ ++K +++ N E+ +KK+ LEE+++
Sbjct: 13221 HMSKMEEREAERKTIE-RVMDEMAEEHE-KIKKEREELVNMEEE--IKKQRRVLEESMNE 13276
Query: 713 LTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRV 594
+T K +ELQ + ++ K+KQ LE +
Sbjct: 13277 MTKKK--------------SELQHERSELYKQKQQLEDMI 13302
Score = 69.3 bits (168), Expect = 1e-08
Identities = 108/561 (19%), Positives = 243/561 (43%), Gaps = 50/561 (8%)
Frame = -3
Query: 2051 EAAIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDE---LERKK 1881
E+ L++E +D+ K + +N+L +K + +LE T + E +E+++
Sbjct: 13845 ESMKTLLDEERRQLQDNIKTFEDQKNVLHPSKTDAVQQTDELEKFTTDIKTEKEHVEKER 13904
Query: 1880 DD----NNAIIK-----KALDKRISDLKAD-APQRDQEDDMNALIXXXXXXXXXXXXXXK 1731
++ N IIK ++L+ I K + A +R Q + + L +
Sbjct: 13905 EEIDVLNKEIIKSKEELQSLNLEIEMFKQEIAGKRAQIESLEQLRADLLAGADDIKTLVQ 13964
Query: 1730 IVSNLEVNI------LILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSL 1569
+ + + L LQK+K++ L ++ + AE K V L+ + + +
Sbjct: 13965 TEKQMAIEDTEKKTEVELQMNLQKQKNELEEL-RNTIEAE--KHQVENRKIMLDKQQKEV 14021
Query: 1568 KEHF-LREEEDEVLERSASNLAIMKAIREEELRKEKDGKSALVENG----EGC----EAE 1416
++ + + E +VLE+ S L + + E++++E++ L+E E C E+E
Sbjct: 14022 EDIMTVIKSERDVLEKEKSELNKLSHVLNEKVQREQEELERLLEKERDDIENCKKIIESE 14081
Query: 1415 KQGLEKTVLERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEP 1236
KQ +E+ E + + ++ HE L ++ DK+ + + E E EK + + +L+
Sbjct: 14082 KQSIERERAELKRLK-EEVEVQHERTLLQQ--DKNMIQKEKEHLEGEKARTTEEIHNLKE 14138
Query: 1235 TIPSLNDALQRDLDRVMAEKQALE--------------KRCSDL---EAKNASLTDNQEG 1107
I + L + A++Q E K+ D+ E TD +
Sbjct: 14139 EIKRKSSELDMLNKEIEAKRQEEELHGLPEEIEIEDHLKKEDDVLREEIIKKQQTDASQK 14198
Query: 1106 HEAEIERKLEASNLTHNDELHKEKDDKKSIMNDLDRVKAEKQVL----ESKVSDLETTYS 939
+ + + +A T DE+ K + ++ + + A++ ++ ++ S+++
Sbjct: 14199 FQLKTTSR-DAETQTSLDEITKTDERRQRALEETVATTAKQPIVIKLEDTLTSEVQEMRD 14257
Query: 938 TLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQ 759
LNNE+++ E+D L+ K ++ ++ + E + + + +++ +
Sbjct: 14258 HLNNEIKELARMKTIMKMEKDQLKQAKSDIQTQMEEFERNMEEAMEEKSRNE-------E 14310
Query: 758 TLKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLELTS 579
L + + E+ + L K K++ + +L ++ +L+ + K+K+++E +L+L
Sbjct: 14311 KLLQLTHDKEDLSNTLDKKNKEIENNTETFLKKIAQLETTIVLMKKDKENIENELLQLKQ 14370
Query: 578 -KLEKCICGARDGLSTIKEAW 519
+ E+ I D ST KE +
Sbjct: 14371 IEQEREIQRKADVTSTEKEMY 14391
Score = 68.9 bits (167), Expect = 2e-08
Identities = 112/521 (21%), Positives = 233/521 (44%), Gaps = 25/521 (4%)
Frame = -3
Query: 2075 LESKVSVFEAAIATLN-DELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLND 1899
LE + FE A ++ E L E+ +++ I N R ++ LE +L AK N+
Sbjct: 3137 LEKERDCFEKEKADISLSEDLKEQSEREGIDNTRTRIKQEMDELEKTRQNL--AKEQENN 3194
Query: 1898 ELERKKDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSN 1719
EL++K II+ DK I +KA+ + ++ + + N
Sbjct: 3195 ELQKK------IIEDERDK-IEQIKAELKKEAEKTKLE-------------------LQN 3228
Query: 1718 LEVNILILHEELQKEKDDKTALIKDLVAAE---PGKRTVNEIVSHLESKSRSLKEHFLRE 1548
N+ +L+K++++ +L ++L + + E+ ++ ++E L E
Sbjct: 3229 ERQNLEEAGTKLKKDRENVESLAEELGRKQVVLENMQIETEMQRKANESNKQMQERVLIE 3288
Query: 1547 EEDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNL 1368
L+++ +++A K E +L +E++ V+ E +AEK L L ++ +
Sbjct: 3289 -----LKKTVTDIAGAKEDLENQLLEEREKNK--VKQAE-IQAEKDML---YLLKQGISE 3337
Query: 1367 DTMDAIHE-EELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLN---DALQRD 1200
+D +++ E+LR +V+ L + E + K +++ + + D LQR+
Sbjct: 3338 QQVDIVNKTEQLRLREVELEQLQALIYRQQDEIEANRKAIINEKYRLEGQKTEIDRLQRE 3397
Query: 1199 LDRVMA----EKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASNLTHNDELHKEKD 1032
++++M ++ LEK S++ A+ + IE + + N KE D
Sbjct: 3398 VNQMMEYASKDRANLEKEKSEMIAQKHQMDIELNKERGLIEERTQMLNT-----YEKEMD 3452
Query: 1031 DKKSIMN-DLDRVKAEKQVLESKVSDLETTYSTLNNELQQKMDD----NEAFLNERDGLE 867
K++ + ++ +K KQ ++ + + L+ + ELQ++ DD E NER LE
Sbjct: 3453 QKRTALEVEMKELKYHKQAIQEEKNKLQQ----MKIELQREADDIKKLKEKTRNERQSLE 3508
Query: 866 AVKQGLEKRVLDLEATIHDIEMKTGKDDDYNE---AEKQTLKKRISELEEAI-----SIL 711
+ + LEK DL D + K + +E A+ Q K + ++ E++ I
Sbjct: 3509 KMAENLEKEKDDLAHLAEDTKRKDDEMKVLHESALADIQKEKCNLEQMRESMFKQNEMID 3568
Query: 710 TDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLE 588
++K K +L++ ++ ++Q ++N++ E D +K ++E
Sbjct: 3569 SEKKKMILRE-----DKLQQMQAEINRQQTE-MDTKKSIIE 3603
Score = 68.9 bits (167), Expect = 2e-08
Identities = 118/565 (20%), Positives = 246/565 (43%), Gaps = 87/565 (15%)
Frame = -3
Query: 2000 KKC-IVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKALD-----KR 1839
+KC I N + I++ +E + +++ K L+ E ++ D+ + +I+ + +R
Sbjct: 10728 EKCDIENSKEIVQKLMVEVEEQKHEIQFQKEELDIERQKIADEQDLLIQNKSELQNENER 10787
Query: 1838 ISDL-KADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDK 1662
I +L + +R+ +M A + + ++ L E+L+K D
Sbjct: 10788 IRNLNEIIKKERETLKEMEAHLEKKKEE----------IKSVSEETRRLKEDLEKMSTDV 10837
Query: 1661 TALIKDLVAAEPGKRTVNEIVSHL----------------ESKSRSLKEHFLREEEDEVL 1530
KDL+ E ++H + K + L + +E+ + L
Sbjct: 10838 NKQNKDLMNQRDLLEQEREEINHKWKQLQQRIDEFDAQVSKQKEQDLPKEKGMKEDRKSL 10897
Query: 1529 ERSASNLAIMKAIRE-EELRKEKDGKSALVENGEG-----CEAEKQGLE--KTVLERRAS 1374
E + +N+ MK E EE++KEK+ ++ E E E E++ L K+ LER S
Sbjct: 10898 EETKANVIEMKTKAEPEEIKKEKEKENEEEEEEEEEIRVIVETERKELYQIKSELERVRS 10957
Query: 1373 NLDT--------MDAIHEEELRKEKV-------------DKSALTENGEGCEAEKQGPEK 1257
+D M I +E+ EK+ ++S L + EK EK
Sbjct: 10958 EIDHEQKKLNDYMKMIEQEKEDLEKMKSEIMKQRQQMEEERSELDNKIQQTNLEKHDIEK 11017
Query: 1256 TVLDLEPTIPSLNDA---LQRDLDRVMAEKQALEKRCSDLEAKNASL-TDNQEGHEAEIE 1089
+ +E + + + +Q + + E+Q + + L A L +N+ + + E
Sbjct: 11018 SKEIVEKLMVEVEEQRKDIQLQKEELDIERQKIADEQNLLVQNKAKLQNENERIKKVDEE 11077
Query: 1088 RKLEASNLTHND-ELHKEKDDKKSIMNDLDRVKAEKQVLESKVSD-----------LETT 945
K E L + L KEK++ +SI+ + R K + + + + +++ LE
Sbjct: 11078 IKKERETLREMEIHLKKEKEELRSIIEETQRRKEDLEKMSTDINEQKLHLKNQRDLLEQE 11137
Query: 944 YSTLNNE---LQQKMDDNEAFLNE------RDGLEAVKQGLEK---RVLDLE--ATIHDI 807
+N+E LQQ++D+ +A +++ + +E ++ LE+ R+++++ A + +I
Sbjct: 11138 REEINHEMTQLQQRIDEFDAQVSKQREDLTKQEMEEERKSLEETKARIIEMKTKAELQEI 11197
Query: 806 EMKTGKDDDYN-----EAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQE 642
+ ++D+ E E++ L + SEL+ S + + KKL D I E +L++
Sbjct: 11198 MQEKEEEDEEEMRVIVEMEREELNQIKSELKRVRSEIDHEQKKLNDDKKIIEQEKEDLEK 11257
Query: 641 DLNKESKEKQDLEKRVLELTSKLEK 567
++ ++Q +E+ EL +K+++
Sbjct: 11258 MKSEIMTQRQQMEEERSELDNKIKQ 11282
Score = 68.2 bits (165), Expect = 3e-08
Identities = 116/566 (20%), Positives = 230/566 (40%), Gaps = 63/566 (11%)
Frame = -3
Query: 2075 LESKVSVFEAAIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDE 1896
+E ++ + +A L + E D++K N+ E Q L+ + +L KT + +
Sbjct: 13001 IEGEIKTKQIEMACLEELKQKELDEQK------NMRECENQELQMRREELAKMKTEI--D 13052
Query: 1895 LERKKDDNNAIIKKALDKRISDLKADAP--QRDQEDDMNALIXXXXXXXXXXXXXXKIVS 1722
+ER D ++K +K +L+ P Q+ + + ++A +
Sbjct: 13053 IER---DEIQKLRKQYEKEKCELEQIKPDLQKREPEKIDAEVQH---------------D 13094
Query: 1721 NLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEE 1542
+ I L EE ++ + K L L AE + + LE K +++ + E+
Sbjct: 13095 EIHGGIDSLKEEREEIEKMKADLQNKLREAENMRDIMKREKDELEKKEAEIEQMAVETED 13154
Query: 1541 DEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKT--VLERRASNL 1368
++ + + ++AI L+ K K+ L + E EK LE +LER + L
Sbjct: 13155 NDSDKNLQDEMMKIEAI----LKVTKKQKNYLEQMNENLTREKTELETNCQMLEREKTEL 13210
Query: 1367 DT---------MDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLND 1215
+ M + E E ++ +++ + E E E K+ E+ V ++E I
Sbjct: 13211 NKKVKETEEFHMSKMEEREAERKTIER-VMDEMAEEHEKIKKEREELV-NMEEEIKKQRR 13268
Query: 1214 ALQRDLDRVMAEKQALEKRCSDLEAKNASLTD---------------NQEGHEAEIERKL 1080
L+ ++ + +K L+ S+L + L D Q+ + +I ++
Sbjct: 13269 VLEESMNEMTKKKSELQHERSELYKQKQQLEDMIASESKRDVDTERSRQDKEDEQILKRE 13328
Query: 1079 EASNLTHNDELHKEKDDKKSIMNDLDRVKAEKQVLESKVSD--------------LETTY 942
D+L KEK+D ++ ++R K + ++S+++D ++T
Sbjct: 13329 REEIADMKDQLLKEKEDVETTKERINREKEHIEKMQSQLNDQKEEMDLENQKLLYMKTEI 13388
Query: 941 STLNNELQQKMDDNEAFLNERDGLEAV-----KQGLEKRVL-------------DLEATI 816
N L++ M D + ER+ + A+ K+ ++ +L +++
Sbjct: 13389 QVKTNALEKMMQDLQ---KERENVNALVIQHQKEREQRDILIEENKRKEKHAEAEIQRQF 13445
Query: 815 HDIE-MKTGKDDDYNEAEKQT--LKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQ 645
DIE +K + N+ +K LK R ELE I KK K+ ++ E+Q
Sbjct: 13446 EDIESVKVRLVTESNQIDKMNSELKTRSEELENLI-------KKQQKEFE---TKENEMQ 13495
Query: 644 EDLNKESKEKQDLEKRVLELTSKLEK 567
+ K +LE++ EL +K+EK
Sbjct: 13496 RERKALEKMNAELERKSTELKNKIEK 13521
Score = 67.8 bits (164), Expect = 4e-08
Identities = 122/593 (20%), Positives = 248/593 (41%), Gaps = 81/593 (13%)
Frame = -3
Query: 2027 DELLNEKD-DKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIK-- 1857
D + + D ++ I N + I++ +E + D+ K L+ E ++ D+ +++
Sbjct: 11277 DNKIKQTDLERHDIENSKEIVQKLMVKVEEQRKDIRLQKEELDIERQKIADEQGLVVQNK 11336
Query: 1856 ----------KALDKRISDLKA-----DAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVS 1722
K +D+ I K +A R ++++M ++I
Sbjct: 11337 AKLQNENERIKEMDEEIKKEKETLKEMEAHLRKEKEEMRSVIEETQRRKKEDLEKMSTDV 11396
Query: 1721 NLEVNILILHEELQKEKDDK-----TALIKDLVAAEPGKRTVNEIVSHL-ESKSRSLKEH 1560
N + L+ +L K++ ++ T L ++ ++E + + + K L +
Sbjct: 11397 NKQNQDLMNQRDLLKQEREEINHKWTQL----------QQRIDEFDAQVSKQKEEDLTKQ 11446
Query: 1559 FLREEEDEVLERSASNLAIMKAIRE-EELRKEKDGKSALVENGEGCEAEKQGLE--KTVL 1389
EEE + LE + + MK E E+++KEK+ + V + E +K+ L+ K+ L
Sbjct: 11447 KKMEEERKSLEETKIKIIEMKTKTEPEKIKKEKEKEEEEVMRAK-VEMKKEELDQIKSQL 11505
Query: 1388 ERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDAL 1209
ER S +D HE+ +K DK + + E E K K +E L++ +
Sbjct: 11506 ERVRSEID-----HEQ--KKLNDDKKMIEQEKEDLEKMKSEIMKQRQQMEEERSELDNKI 11558
Query: 1208 -QRDLDR--VMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIER---------------K 1083
Q DL+R + K+ ++K ++E + + +E E +IER K
Sbjct: 11559 KQTDLERHDIENSKEIVQKLMVEVEEQRKDIRLQKE--ELDIERQKIADEQGLVVQNKAK 11616
Query: 1082 LEASN---LTHNDELHKEKDDKKSIMNDLDRVKAE-KQVLES----KVSDLETTYSTLNN 927
L+ N ++E+ KEK+ K + L + K E + V+E + DLE + +N
Sbjct: 11617 LQNENERIKEMDEEIKKEKETLKEMEAHLRKEKEEMRSVIEETQRRQKEDLEKMSTDVNK 11676
Query: 926 ELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATI-----HDIEMKTGKDDDYNEAEK 762
+ Q M+ + ER+ + L++R+ + +A + D+ + +++ E+
Sbjct: 11677 QNQDLMNQRDLLKQEREEINHKWTQLQQRIDEFDAQVSKQKEEDLTKQKKMEEERKSLEE 11736
Query: 761 QTL---------------KKRISELEEAISILTDKAKKLLKDINIWL----SEVTELQED 639
+ K++ E EE + + K+ L I L SE+ Q+
Sbjct: 11737 TKIKIIEMKTKTEPEKIKKEKEKEEEEVMRAKVEMKKEELDQIKSQLERVRSEIDHEQKK 11796
Query: 638 LNKESK----EKQDLEKRVLELTSKLEKCICGARDGLSTIKEAWMSDCMVPDN 492
LN + K EK+DLEK E+ + ++ + + I++ ++ C + ++
Sbjct: 11797 LNDDKKMIEQEKEDLEKMKSEIMKQRQQMEEERSELENKIRQTYIEKCDIENS 11849
Score = 67.4 bits (163), Expect = 5e-08
Identities = 92/447 (20%), Positives = 194/447 (43%), Gaps = 36/447 (8%)
Frame = -3
Query: 1622 KRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNLAIMKAIREEELRKEKDG-KSAL 1446
+ T E++ LE + R+ K R L + +++K KD K
Sbjct: 80 RMTEPELIQELEWRQRNTKHTQTETGSPPSSPREKRRLEDKSGL-SSDIQKRKDSLKRRR 138
Query: 1445 VENGEGCEAEKQGLEKTVLERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQG 1266
E E ++ E T ER + +D M ++++++++ + + +T EK
Sbjct: 139 FETMRAIEQIEKLWEGTKQER--TEIDNM----KQKIQRQQDEITRMT-------TEKGQ 185
Query: 1265 PEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIER 1086
E+T+ ++ I + + + R+ + V E++ +E+ SDL+A+ +SL Q+ E ER
Sbjct: 186 LERTITHMKAEIDHIRERMDRNKEEVNRERERVEQMRSDLQAEQSSL--QQKRDEIMTER 243
Query: 1085 K----LEASNLTHNDELHKEKDDKKSIMNDLDRVKAEKQV----LESKVSDLETTYSTL- 933
+ + L +EL ++ K M ++++K+ QV +E K+ + + +
Sbjct: 244 QNLEMIRYETLRQQEELESNRESTKHEMERMEQMKSAIQVQINEIEMKIGETQKAKDLME 303
Query: 932 ---------NNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDD 780
NEL++K +D +RD E +K L++ +++E H+ E + +
Sbjct: 304 QMKAEIEDEKNELEKKKED---IKRQRDQFEQIKLDLQQVKMEMEQRWHETEKEGLEQRA 360
Query: 779 YNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEV--TELQEDLNKESK----- 621
+ EK+ LK E++ + ++ ++ K + +S++ L+E+ E+K
Sbjct: 361 VIQREKEQLKYLQDEIQR-VREEVERNREFSKQEHARISQLRAQALEENNLIENKWHDIL 419
Query: 620 -EKQDLEKRVLELTSKLEKCICGARDGLSTIKEAW----MSDCMVPDNWVPFEDLVQGFS 456
+++DLE+ E+ E+ + +K+ W + + + + E V
Sbjct: 420 RKEKDLEEMKHEIERGREELVMNG----ELVKKEWEKIEQAKVDIQSHMISMEGRVDEIK 475
Query: 455 RKTSPLDITKT-----CDAVDISEDST 390
R+T L KT DA++ +D T
Sbjct: 476 RETERLKHIKTEMQRDKDALEKQKDDT 502
Score = 65.1 bits (157), Expect = 2e-07
Identities = 117/597 (19%), Positives = 242/597 (40%), Gaps = 108/597 (18%)
Frame = -3
Query: 2033 LNDELLNEKDDKKCIVN--------DRNILEAAKQALEYKVADLEAAKTTLNDELERKKD 1878
LN+ LN+ K ++ ++ +E K ++ + DL+ +T LN + + +D
Sbjct: 1889 LNELTLNQIKTKSDVLEKISELNSQQKDEIENEKSKIKIREYDLQQMQTDLNRQQKEMQD 1948
Query: 1877 DNNAII--KKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLE-VN 1707
NA+ K L K ++ A Q Q DM NL+
Sbjct: 1949 IQNAVFMEKSELKKSQDEI---AEQLKQVGDMMQFTQNEK-------------DNLDRER 1992
Query: 1706 ILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEV-L 1530
I+ ++LQ E+D L ++L + + K+ V LE SL E+ ++ L
Sbjct: 1993 AAIIEQKLQMERDMTHLLNRELESLKLVKKEVLNEKRLLEDCRISLMRDMQDLEQMKINL 2052
Query: 1529 ERSASNLAIMKAIREEELRKEKDGKSALVENGEGCE----AEKQGLEKTVLERRASNLDT 1362
ER + + + EE K + L E+ E AEKQ LE +E + +
Sbjct: 2053 EREKEEMQLQRQSIAEEKDKLESVLQTLAEDTEKLRIDTLAEKQKLEDAAVELQKERDEI 2112
Query: 1361 MDAIHEEELRKEKVDK----------------------SALTENGEGC------------ 1284
M+ E + ++E VDK +A+ EN
Sbjct: 2113 MNIAEETKRKREDVDKIRVGIEKQEITFKDLKADLQKEAAIVENQRQAVQKDIQNVKDME 2172
Query: 1283 ---EAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQ 1113
+ E+Q ++ V ++E +L D +Q ++D+ E+Q +E + +LE + + L +++
Sbjct: 2173 VQIQKERQYMDRLVEEIEKRTKAL-DEMQMEVDK---ERQEVESKRDELEQETSKLREDE 2228
Query: 1112 EGH----------EAEIERK-----LEASNLT----------------HNDELHKEK--D 1032
+ +AEI+++ L++ N++ N+ +K+K D
Sbjct: 2229 DEFSRQKEKNNIIQAEIQKESDNLELQSENISKERTIFELEKEHLGLRENEAEYKQKQID 2288
Query: 1031 DKKSIMN----DLDRVKAEKQVLESKVSDLETTYSTLNNELQQKMDDNEAFLNERDGLEA 864
+ ++ + +++++A+K K ++T L+++ + E+ E + +E
Sbjct: 2289 ELQNKLRMEKVQVEQMQADKDQQRKKAEYVKTARGRETTALEEQRQEMESLREEYENVEK 2348
Query: 863 VKQGLEKRVLDLEATIHDIEMKTGKDDDYNEA----------EKQTLKKRISELEEAISI 714
K+ + ++ E+ + +EM+ Y E ++Q +K I ++ + I
Sbjct: 2349 QKKHVNEQKELFESRMKSLEMENEAMKKYKEKLDKEYEDLQFQRQLFEKEIQQMRTELQI 2408
Query: 713 LTDKAKKLLKDINIWLSEV------TELQEDLNKESK--EKQDLEKRVLELTSKLEK 567
+ ++ K++ I V E Q+ + ++SK E ++ K++ S++EK
Sbjct: 2409 EAENIERKKKELEIQKPAVYTETYMLETQKPVVEKSKTDELDEVRKKINADLSEVEK 2465
Score = 65.1 bits (157), Expect = 2e-07
Identities = 108/563 (19%), Positives = 242/563 (42%), Gaps = 74/563 (13%)
Frame = -3
Query: 2033 LNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIK- 1857
L++++ +K I + I+E +E + D++ K L+ E ++ D+ N +++
Sbjct: 11001 LDNKIQQTNLEKHDIEKSKEIVEKLMVEVEEQRKDIQLQKEELDIERQKIADEQNLLVQN 11060
Query: 1856 -----------KALDKRISDLKADAPQRD-----QEDDMNALIXXXXXXXXXXXXXXKIV 1725
K +D+ I + + + +++++ ++I +
Sbjct: 11061 KAKLQNENERIKKVDEEIKKERETLREMEIHLKKEKEELRSIIEETQRRKEDLEKMSTDI 11120
Query: 1724 SNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREE 1545
+ ++++ + L++E+++ + L ++ ++E + + + L + + EE
Sbjct: 11121 NEQKLHLKNQRDLLEQEREEINHEMTQL------QQRIDEFDAQVSKQREDLTKQEM-EE 11173
Query: 1544 EDEVLERSASNLAIMKAIRE-EELRKEKDGKS-----ALVENGEGCEAEKQGLEKTVLER 1383
E + LE + + + MK E +E+ +EK+ + +VE E E+ K+ L+R
Sbjct: 11174 ERKSLEETKARIIEMKTKAELQEIMQEKEEEDEEEMRVIVE----MEREELNQIKSELKR 11229
Query: 1382 RASNLDTMDAIHEEE--------LRKEKVD----KSALTENGEGCEAEKQGPEKTV--LD 1245
S +D HE++ + +EK D KS + + E E+ + + D
Sbjct: 11230 VRSEID-----HEQKKLNDDKKIIEQEKEDLEKMKSEIMTQRQQMEEERSELDNKIKQTD 11284
Query: 1244 LEP-TIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASN 1068
LE I + + +Q+ + +V +++ + + +L+ + + D Q G + + KL+ N
Sbjct: 11285 LERHDIENSKEIVQKLMVKVEEQRKDIRLQKEELDIERQKIADEQ-GLVVQNKAKLQNEN 11343
Query: 1067 ---LTHNDELHKEKDDKKSIMNDLDRVKAE-KQVLES----KVSDLETTYSTLNNELQQK 912
++E+ KEK+ K + L + K E + V+E K DLE + +N + Q
Sbjct: 11344 ERIKEMDEEIKKEKETLKEMEAHLRKEKEEMRSVIEETQRRKKEDLEKMSTDVNKQNQDL 11403
Query: 911 MDDNEAFLNERDGLEAVKQGLEKRVLDLEATI-----HDIEMKTGKDDDYNEAEKQTL-- 753
M+ + ER+ + L++R+ + +A + D+ + +++ E+ +
Sbjct: 11404 MNQRDLLKQEREEINHKWTQLQQRIDEFDAQVSKQKEEDLTKQKKMEEERKSLEETKIKI 11463
Query: 752 -------------KKRISELEEAISILTDKAKKLLKDINIWL----SEVTELQEDLNKES 624
K++ E EE + + K+ L I L SE+ Q+ LN +
Sbjct: 11464 IEMKTKTEPEKIKKEKEKEEEEVMRAKVEMKKEELDQIKSQLERVRSEIDHEQKKLNDDK 11523
Query: 623 K----EKQDLEKRVLELTSKLEK 567
K EK+DLEK E+ + ++
Sbjct: 11524 KMIEQEKEDLEKMKSEIMKQRQQ 11546
Score = 62.8 bits (151), Expect = 1e-06
Identities = 107/536 (19%), Positives = 227/536 (42%), Gaps = 55/536 (10%)
Frame = -3
Query: 2027 DELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKAL 1848
+ L KD+ + +R+ LE K ++E NDE++++K + K L
Sbjct: 8031 ETLRGMKDEVQAARKERSELENMKLEFLTMKKNMEKTYEQQNDEIQKEKQQIESS-KMLL 8089
Query: 1847 DKRISDLKADAPQRDQED-----DMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEEL 1683
+ +DL+ + +++ D L+ KI+ NLE L EE
Sbjct: 8090 SRERNDLEQNRADLERQKQIMALDKQKLLAENELLEREKADVIKIIENLES----LREEA 8145
Query: 1682 QKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVLE--RSASNL 1509
+E+ +TA + +R E++ +E+ S E F +++++E R L
Sbjct: 8146 TRERATETA--------QATRRDSEELMQKMEALSM---EDFQEASKNQMVELKRQIDKL 8194
Query: 1508 AIMKAI---REEELRKEKDG-----------KSALVENGEGCEAEKQGLEKTVLERRASN 1371
+KA ++ EL+K K +S ++++ + +++ + LE ++R+ +
Sbjct: 8195 IELKADLLQQQTELKKTKADLKQQMDDLEKTRSEILKHEKDTDSKTRELELIEIQRQKDD 8254
Query: 1370 LDT------MDAIHEEELRKEKV-DKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLN-- 1218
L+T ++ E LR E V +K L + + ++ EK D+ +N
Sbjct: 8255 LETRIQKLTLEKRDLEVLRSEIVLEKKDLDQKMKQVIRKRDEMEKIRSDIANATEEINRE 8314
Query: 1217 ----DALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQE-------------GHEAEIE 1089
+ L+ ++ + + L +R ++LE + ++ TD + + E+E
Sbjct: 8315 RQELEILRNNVQSARHDFELLLERTANLEDEESAATDIERLVLEVVKIREMVRNLKGEME 8374
Query: 1088 RKLEASNLTHNDELHKEKDDKKSIMNDLDRVKAEKQVLESKVS-------DLETTYSTLN 930
R++E S + DE K + + + D+ +++ L ++ +LE + L
Sbjct: 8375 RRMEKSKV-EIDEKEIFKSEIQRFIQDIGQIRENLGGLGEEIEKTRRDKRELEKMRAELA 8433
Query: 929 NELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLK 750
+ Q++ E ER+ LE +K + + D+E +E K++ + Q K
Sbjct: 8434 EKQQEQESMREMLHKEREELEQLKDEINREKEDVEIRRELVEAVIDKEEMKEFTDIQKYK 8493
Query: 749 KRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLN-KESKEKQDLEKRVLEL 585
+ + + E +LT K+ L +N + ++ + E++N + K++ +LE EL
Sbjct: 8494 EELQSVTE--ELLT--KKRDLDQLNSDVQDLRQTIEEINIQHGKKRAELEGIGFEL 8545
Score = 62.4 bits (150), Expect = 2e-06
Identities = 121/544 (22%), Positives = 221/544 (40%), Gaps = 48/544 (8%)
Frame = -3
Query: 2081 QALESKVSVFEAAIATLNDELLNEKDDKKCIVNDRNILEAAKQ--ALEYKVADLEAAK-- 1914
Q L+++ + E + T ND LL E +K+ ND + E K+ ALE + D+ K
Sbjct: 13723 QLLQTEKEILEKS-KTEND-LLREDLEKQRKRNDLTLQELRKEKMALEQMITDITKEKDA 13780
Query: 1913 -TTLNDELERKKDD--NNAIIKKALDKRISDLKADAPQRD-----QEDDMNALIXXXXXX 1758
+L +E+ K+ + N K + DL+ R Q+ +++ I
Sbjct: 13781 VASLQNEVSLKQHELKNKETELDEQRKEMDDLRMQLEMRQNSTNKQQQEVDVFIVENMKM 13840
Query: 1757 XXXXXXXXKIVSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKS 1578
++LE +L EE ++ +D+ P K + LE +
Sbjct: 13841 R----------NDLESMKTLLDEERRQLQDNIKTFEDQKNVLHPSKTDAVQQTDELEKFT 13890
Query: 1577 RSLK---EHFLREEEDEVLERSASNLAIMKAIRE--------EELRKEKDGKSALVENGE 1431
+K EH +E E E N I+K+ E E ++E GK A +E+ E
Sbjct: 13891 TDIKTEKEHVEKERE----EIDVLNKEIIKSKEELQSLNLEIEMFKQEIAGKRAQIESLE 13946
Query: 1430 GCEAE----KQGLEKTVLERRASNLDTMDAIHEEELRKE-KVDKSALTENGEGCEAEKQG 1266
A+ ++ V + ++ + E EL+ + K+ L E EAEK
Sbjct: 13947 QLRADLLAGADDIKTLVQTEKQMAIEDTEKKTEVELQMNLQKQKNELEELRNTIEAEKHQ 14006
Query: 1265 PEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIER 1086
E + L+ + D + + +E+ LEK S+L + L + + + E+ER
Sbjct: 14007 VENRKIMLDKQQKEVEDIMTV----IKSERDVLEKEKSELNKLSHVLNEKVQREQEELER 14062
Query: 1085 KLEASNLTHNDELHKEKDDKKSIMNDLDRVKAEKQVLESKVSDLETTYSTLNNELQQKM- 909
LE KE+DD I N +++EKQ +E + ++L+ + + ++ +
Sbjct: 14063 LLE-----------KERDD---IENCKKIIESEKQSIERERAELKRLKEEVEVQHERTLL 14108
Query: 908 -DDNEAFLNERDGLEA-----------VKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAE 765
D E++ LE +K+ ++++ +L+ +IE K +++ + E
Sbjct: 14109 QQDKNMIQKEKEHLEGEKARTTEEIHNLKEEIKRKSSELDMLNKEIEAKRQEEELHGLPE 14168
Query: 764 ----KQTLKKRISELEEAI--SILTDKAKKL-LKDINIWLSEVTELQEDLNKESKEKQDL 606
+ LKK L E I TD ++K LK + T L E + + ++ L
Sbjct: 14169 EIEIEDHLKKEDDVLREEIIKKQQTDASQKFQLKTTSRDAETQTSLDEITKTDERRQRAL 14228
Query: 605 EKRV 594
E+ V
Sbjct: 14229 EETV 14232
Score = 62.0 bits (149), Expect = 2e-06
Identities = 117/582 (20%), Positives = 218/582 (37%), Gaps = 78/582 (13%)
Frame = -3
Query: 2081 QALESKVS-VFEAAIATLND--ELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKT 1911
Q LE+KV V + T D EL +E ++K I+ + N + Q L+ + E K+
Sbjct: 14774 QTLETKVQDVLQLTDYTTQDQEELHDEMENKMKIILELNEAKKDLQKLKEECRSAEEEKS 14833
Query: 1910 TLNDELERKKDDNNAIIKKALD-----KRISDLKADAPQ--------------------- 1809
+ + LER+++ + + L ++ +K + Q
Sbjct: 14834 VIMESLERRRNSLEKVQSEVLSLTQEIDHLAQIKTEMQQIEIKMQIQTRSVATQWETDVQ 14893
Query: 1808 ----RDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDKTALIKDL 1641
++ + + V+ LE L E+Q+ +D ++D+
Sbjct: 14894 IQQGQEATETTGHITKKSEEEISAKKTKQPTVTKLEDT---LTSEVQEMRDSLNKEMEDV 14950
Query: 1640 VAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNLAIMKAIRE-EELRKEK 1464
+ + + + +S ++ E F R E+ + E+S + +++ + E+L
Sbjct: 14951 ARMKTIMKMEKDQLEQAKSDIQTQMEEFERNMEEAMEEKSRNEEKLLQLTHDKEDLSNTL 15010
Query: 1463 DGKSALVENG----------------------EGCEAEKQGLEKTVLERRASNLDTMDAI 1350
D K+ +EN E E E L++T ER T D
Sbjct: 15011 DKKNKEIENNTETSLKKIAQLETTIVLMKKDKENIENELLQLKQTEQEREIQR-GTDDTS 15069
Query: 1349 HEEELRKEKVD-KSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQ 1173
+E E EKV K+ L +N E +K+ + L L D+ + D +R E Q
Sbjct: 15070 NEREKYDEKVTYKTELEDNKE----KKKPDRDSSLKLTDA-----DSAKTDGER---EAQ 15117
Query: 1172 ALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASNLTHNDELHKEKDDKKSIMNDLDRVK 993
LE + D+ T +QE ELH E ++K I+ +L+ K
Sbjct: 15118 TLETKVQDVLQLTDDTTQDQE-------------------ELHDEMENKMKIILELNEAK 15158
Query: 992 AEKQVLESKVSDLETTYSTLNNELQQKMDDNE-------AFLNERDGLEAVKQGLEKRVL 834
+ Q L+ K E S + L+++ + E E + L +K +++
Sbjct: 15159 KDLQKLKEKCRSAEEEKSVIMESLERRRNSLEKVQSEVLTLTQEIEHLAQIKTEMQQIET 15218
Query: 833 DLEATIHDIEMKTGKDDDYNEAEKQTLKKR---ISELEEAISILTDKAKKLLKDINIWLS 663
++ + + D + ++ + R + EE IS K + K + S
Sbjct: 15219 KMQRQTRSVATQWETDVQIQQEGQEATETRGHITKKSEEEISAKKTKQPTVTKLEDTLTS 15278
Query: 662 EVTELQEDLNKESK-----------EKQDLEKRVLELTSKLE 570
EV E+++ LNKE + EK LE+ +L ++E
Sbjct: 15279 EVQEMRDSLNKEMEDVERMKTMMKMEKDQLEQAKSDLQRQME 15320
Score = 60.5 bits (145), Expect = 6e-06
Identities = 105/514 (20%), Positives = 211/514 (41%), Gaps = 39/514 (7%)
Frame = -3
Query: 1985 NDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKALDKRISDLKADAPQR 1806
++ ++ EA Q AD+E ELE+ KD+ K + K DL+ +
Sbjct: 1701 DELSLREATLQTATQTTADMELQLELQKQELEQTKDEMER-TKLEVQKGWVDLQTQIAES 1759
Query: 1805 DQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDKTALIKDLVAAEP 1626
++++M + +++ + ++ E+ E D K L K+ E
Sbjct: 1760 REKEEMVRI---------ELEKARDVLNRIRQDVET--EKQTMEADLKFTLAKEFENLEA 1808
Query: 1625 GKRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNLAIMKAIREEELRKEKDGKSAL 1446
++ + + LE+ L + E +ERS N+ +E + ++ L
Sbjct: 1809 QRKMMEDEKRALENMKYEL------QRESGYIERSKHNM-------HDERQNMENWAEKL 1855
Query: 1445 VENGEGCEAEKQGLE--KTVLERRASNLDTMDAIHEEELRKEKVDKSAL-------TENG 1293
+ E E ++ ++ +T R +L+ + ++E L + K L ++
Sbjct: 1856 KQEWEELEKKRHDMQQLQTERSREIKDLENLRELNELTLNQIKTKSDVLEKISELNSQQK 1915
Query: 1292 EGCEAEKQGPEKTVLDLEPTIPSLN---DALQRDLDRVMAEKQALEKRCSDLEAKNASLT 1122
+ E EK + DL+ LN +Q + V EK L+K ++ + +
Sbjct: 1916 DEIENEKSKIKIREYDLQQMQTDLNRQQKEMQDIQNAVFMEKSELKKSQDEIAEQLKQVG 1975
Query: 1121 DNQEGHEAE-----------IERKLEAS-NLTH--NDELHKEKDDKKSIMNDLDRVKAEK 984
D + + E IE+KL+ ++TH N EL K KK ++N+ ++ +
Sbjct: 1976 DMMQFTQNEKDNLDRERAAIIEQKLQMERDMTHLLNRELESLKLVKKEVLNEKRLLEDCR 2035
Query: 983 QVLESKVSDLETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGL----EKRVLDLEA-- 822
L + DLE L E ++ ++ E+D LE+V Q L EK +D A
Sbjct: 2036 ISLMRDMQDLEQMKINLEREKEEMQLQRQSIAEEKDKLESVLQTLAEDTEKLRIDTLAEK 2095
Query: 821 -TIHD--IEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTE 651
+ D +E++ +D+ N AE+ KR E + I + +K + KD+ L +
Sbjct: 2096 QKLEDAAVELQKERDEIMNIAEE---TKRKREDVDKIRVGIEKQEITFKDLKADLQKEAA 2152
Query: 650 LQED----LNKESKEKQDLEKRVLELTSKLEKCI 561
+ E+ + K+ + +D+E ++ + +++ +
Sbjct: 2153 IVENQRQAVQKDIQNVKDMEVQIQKERQYMDRLV 2186
>ref|XP_009292627.1| PREDICTED: nesprin-1 isoform X3 [Danio rerio]
Length = 15657
Score = 103 bits (256), Expect = 8e-19
Identities = 128/547 (23%), Positives = 231/547 (42%), Gaps = 48/547 (8%)
Frame = -3
Query: 2033 LNDELLNEKDDKKCIVND----RNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNA 1866
+ +EL EK+ + D + IL+ K A E +ADL+ K+ L + E
Sbjct: 5015 MTEELKKEKESFTHLAEDTKTEKKILDKMKVANESLMADLQKEKSNLEEMRENISKQTED 5074
Query: 1865 IIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEE 1686
K+ R+ + + + Q + + K V +L+ + L +
Sbjct: 5075 SEKEKEKIRLREDELEQLQAEIHKQQGEIKMEKSNNESERAAIIKDVKDLQHKMFSLDRD 5134
Query: 1685 LQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVL-------- 1530
L+ K D+ A E + + +I + L+ K+ +++ L + D
Sbjct: 5135 LESLKLDREAF-------ENEREVLKQIKTDLKRKAEEIEKIKLETQHDRQRVEEMTAQI 5187
Query: 1529 --ERSASNLAIMKAIREEELRKE-----KDGKSALVENGEGCEAEKQGLEKT--VLERRA 1377
ER N I + R++ + E K+ A+ + + E EK LEKT L R
Sbjct: 5188 QKERDKINNLIEETNRKDMVLNEIKTEIKEKIKAIESDRDMLEKEKHDLEKTRSKLLRAK 5247
Query: 1376 SNLDTMDAIHEEELRKEKVDKSALTE------NGEGCEAEKQGPEKTVLD-LEPTIPSLN 1218
NL+ I E++KE+ D + E + + E+ ++ LD L+ I +L
Sbjct: 5248 ENLEKQRKIKLAEIQKEREDLEKMNEKFTIEIHDIKHQEEQMKQKQDELDQLKTEIQNLQ 5307
Query: 1217 DALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIER--KLEASNLTHNDELH 1044
L+++ + +M ++ L+ R S+L+ + ++ D E + E ++ K + E+
Sbjct: 5308 QELEKEKEIIMKDRSQLDLRQSELDKQQTNVNDIMETMKNERKQLDKDKEETEEQKQEME 5367
Query: 1043 KEKDD----KKSIMNDLDRVKAEKQVLESKVSDLETTYSTLNNELQQKMDDNEAFLNERD 876
KEK D +KS+ DL +K +KQVLE + S LE L E + E NER
Sbjct: 5368 KEKHDFDQSRKSLDEDLKMMKLQKQVLEDEKSKLEQMKIELEREAVEIRKIKEEIQNERQ 5427
Query: 875 GLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTL------KKRISELEEAISI 714
LE + + L++ DL + + D+ A + TL K + E+ E IS
Sbjct: 5428 NLEKMTEALKEEREDL---AEETKKNNQVLDEMKVANESTLADILREKSNLEEMRENISK 5484
Query: 713 LTDKAKKLLKDINIWLSEVTELQEDLNKE----SKEKQDLEKRVLELTSKLE----KCIC 558
T+ + +++ + E+ +LQ +++K+ KEK ++E + +E K IC
Sbjct: 5485 QTEDVENKKENLRLREDELRQLQAEIHKQQREIEKEKINIESERAAIIKDVEDLQHKIIC 5544
Query: 557 GARDGLS 537
RD S
Sbjct: 5545 LDRDAES 5551
Score = 100 bits (248), Expect = 7e-18
Identities = 131/576 (22%), Positives = 258/576 (44%), Gaps = 33/576 (5%)
Frame = -3
Query: 2027 DELLNEKDDK-----KCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAI 1863
D +LNEK+ K I +D+++LE K LE ++L K ++LE++K++ A
Sbjct: 6492 DMVLNEKNRDIEKKIKSIQSDKDMLEKEKHDLEKTRSELYKVK----EDLEKQKENTLAQ 6547
Query: 1862 IKKA---LDKRISDLKADAPQ-RDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILIL 1695
I+K L+K ++ + + + QE+ MN + L+ I L
Sbjct: 6548 IQKEREDLEKMNENITREMHEIKHQEEQMNQ--------------KQDELDQLKTEIQNL 6593
Query: 1694 HEELQKEKD----DKTALIKDLVAAEPGKRTVNEIVSHLESKSRSL-KEHFLREEEDEVL 1530
+EL+KEK+ ++ L + + + +N+I+ ++++ + L K+ EE+ + +
Sbjct: 6594 QQELEKEKEIIMKARSQLDRRQSELDKQQTNMNDIMETMKNERKQLDKDKEEMEEQKQEM 6653
Query: 1529 ERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAI 1350
E+ N+ + +E+L+ K K + E E K LE+ + R +T +
Sbjct: 6654 EKERDNMDQSRKSLDEDLKMMKLQKQVIEEEKNKLEQMKIELEREADDIRKIKEETQNKR 6713
Query: 1349 H-----EEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVM 1185
EEL+KE+ D + L E+ + EK ++ + E ++ L Q++ +
Sbjct: 6714 QILEKMAEELKKERKDVAHLAED---TKREKNSLDEMKVANESSMADL----QKEKSNLE 6766
Query: 1184 AEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASNLTHNDELHKEKDDKKSIMNDL 1005
K+ + K+ D+E + D E E+E+ L+A E+HK++ + + +++
Sbjct: 6767 EMKENISKQTEDIEKEK----DKIRLREDELEQ-LQA-------EIHKQQSETEIEKSNI 6814
Query: 1004 DRVKAEKQVLESKVSDLETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLE 825
+R E+ + V DL++ +L+ + + D EAF NE++ L+ +K LE+ ++E
Sbjct: 6815 ER---ERAAIIKDVEDLQSKIISLDRDAESLKLDREAFENEKEELKQMKTELEREADEIE 6871
Query: 824 ----ATIHD----IEMKTGKDDDYNEAEKQTLKKRI------SELEEAISILTDKAKKLL 687
T H+ EM + N KQ K ++ E+E+ + K L
Sbjct: 6872 KIKLETQHERQRVEEMTADFMETMNNERKQLDKNKVMIEEQKQEMEKKRDDMDQSRKSLD 6931
Query: 686 KDINIWLSEVTELQEDLNKESKEKQDLEKRVLELTSKLEKCICGARDGLSTIKEAWMSDC 507
+D+ + ++ L+E+ NK + K LE+ E+ SK+++ R L + A +
Sbjct: 6932 EDLKMMKAQKQVLEEEKNKLEQMKIGLEREADEI-SKIKEETQNERQNLEKMANALKEE- 6989
Query: 506 MVPDNWVPFEDLVQGFSRKTSPLDITKTCDAVDISE 399
E L + RK LD K + +++
Sbjct: 6990 --------REYLAEEIKRKNQVLDKIKVANESTLAD 7017
Score = 97.1 bits (240), Expect = 6e-17
Identities = 130/534 (24%), Positives = 241/534 (45%), Gaps = 47/534 (8%)
Frame = -3
Query: 2027 DELLNE-----KDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLND-------ELERK 1884
D +LNE K+ K I +DR++LE K LE + L AK L E++++
Sbjct: 5205 DMVLNEIKTEIKEKIKAIESDRDMLEKEKHDLEKTRSKLLRAKENLEKQRKIKLAEIQKE 5264
Query: 1883 KDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNI 1704
++D + +K I D+K Q Q+ D + L+ I
Sbjct: 5265 REDLEKMNEK-FTIEIHDIKHQEEQMKQKQDE--------------------LDQLKTEI 5303
Query: 1703 LILHEELQKEKD----DKTALIKDLVAAEPGKR--TVNEIVSHLESKSRSL-KEHFLREE 1545
L +EL+KEK+ D++ L DL +E K+ VN+I+ ++++ + L K+ EE
Sbjct: 5304 QNLQQELEKEKEIIMKDRSQL--DLRQSELDKQQTNVNDIMETMKNERKQLDKDKEETEE 5361
Query: 1544 EDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLD 1365
+ + +E+ + + +E+L+ K K L + E K LE+ +E R
Sbjct: 5362 QKQEMEKEKHDFDQSRKSLDEDLKMMKLQKQVLEDEKSKLEQMKIELEREAVEIRKIK-- 5419
Query: 1364 TMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVM 1185
+ I E EK+ + AL E E E + + + +++ S + R+ +
Sbjct: 5420 --EEIQNERQNLEKMTE-ALKEEREDLAEETKKNNQVLDEMKVANESTLADILREKSNLE 5476
Query: 1184 AEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASNLTHNDELHKEKDDKKSIMNDL 1005
++ + K+ D+E K +N E E+ R+L+A E+HK++ + I +
Sbjct: 5477 EMRENISKQTEDVENKK----ENLRLREDEL-RQLQA-------EIHKQQ---REIEKEK 5521
Query: 1004 DRVKAEKQVLESKVSDLETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLE 825
+++E+ + V DL+ L+ + + D EAF NE++ L+ +K LE+ ++E
Sbjct: 5522 INIESERAAIIKDVEDLQHKIICLDRDAESLKLDREAFENEKEVLKQMKTELEREADEIE 5581
Query: 824 ----ATIHD--------IEMKTGKDDDYNEAEK-----QTLKKRISELEEAI-SILTDK- 702
T HD +++ +D+ N E+ L ++ ++EE I SI +DK
Sbjct: 5582 KIKLETQHDRQRVEEMAAQIQKDRDEINNLIEETNRKDMVLNEKNRDIEEKIKSIQSDKD 5641
Query: 701 -AKKLLKDINIWLSEVTELQEDLNKE--------SKEKQDLEKRVLELTSKLEK 567
+K D+ SE+ +++EDL K+ KE++DLEK +T ++ +
Sbjct: 5642 MLEKEKHDLEKTRSELYKVKEDLEKQKENTLAEIQKEREDLEKMNENITREMHE 5695
Score = 93.2 bits (230), Expect = 8e-16
Identities = 131/541 (24%), Positives = 244/541 (45%), Gaps = 54/541 (9%)
Frame = -3
Query: 2027 DELLNEKDDK-----KCIVNDRNILEAAKQALE------YKVA-DLEAAKTTLNDELERK 1884
D +LNEK+ K I +D+++LE + LE YKV DLE K E++++
Sbjct: 6075 DMVLNEKNRDIEEKIKSIQSDKDMLEKERHNLEKTRSELYKVKEDLEKQKENTLAEIQKE 6134
Query: 1883 KDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNI 1704
++D + + + + + ++K Q +Q+ D + L+ I
Sbjct: 6135 REDVEKM-NENITREMHEIKHQEEQMNQKQDE--------------------LDQLKTEI 6173
Query: 1703 LILHEELQKEKD----DKTALIKDLVAAEPGKR--TVNEIVSHLESKSRSL-KEHFLREE 1545
L +EL+KEK+ D++ DL +E K+ +N+I+ ++++ + L K+ EE
Sbjct: 6174 QNLQQELEKEKEIIMKDRSQF--DLRQSELDKQQTNMNDIMETMKNERKQLDKDKEEMEE 6231
Query: 1544 EDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLD 1365
+ + +E+ + + +++L+ K K E E K LE+ E R +
Sbjct: 6232 QKQEMEKEKHDFDQSRKSLDKDLKMMKLQKQVFEEEKNKLEQMKIELEREADEIRKIKEE 6291
Query: 1364 TMDAIHE-----EELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRD 1200
T + EEL+KEK + L E+ + E+ +LD + N++L D
Sbjct: 6292 TQNERQSLEKMTEELKKEKESFTHLAEDTK--------KEQEILD---KVKVANESLMAD 6340
Query: 1199 LDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIER--KLEASNLTHNDELHKEKDDK 1026
L + EK LE+ ++ + + + +E + +L+A E+ KEK +
Sbjct: 6341 LQK---EKSNLEEMRENISKQTEDVENKKENLRLREDELWQLQAEIYKQQREIEKEKIN- 6396
Query: 1025 KSIMNDLDRVKAEKQVLESKVSDLETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLE 846
+++E+ + V DL+ +L+ + + D EAF NER+ L+ +K LE
Sbjct: 6397 ---------IESERAAIIKNVEDLQHKIISLDRDSESLKLDREAFENEREVLKQMKTELE 6447
Query: 845 KRVLDLE----ATIHD---IEMKTG---KD-DDYNEAEKQT------LKKRISELEEAI- 720
+ ++E T HD +E T KD D N ++T L ++ ++E+ I
Sbjct: 6448 READEIEKIKLETQHDRQRVEEMTAQIQKDRDKINNLIEETNRKDMVLNEKNRDIEKKIK 6507
Query: 719 SILTDK--AKKLLKDINIWLSEVTELQEDLNKE--------SKEKQDLEKRVLELTSKLE 570
SI +DK +K D+ SE+ +++EDL K+ KE++DLEK +T ++
Sbjct: 6508 SIQSDKDMLEKEKHDLEKTRSELYKVKEDLEKQKENTLAQIQKEREDLEKMNENITREMH 6567
Query: 569 K 567
+
Sbjct: 6568 E 6568
Score = 91.7 bits (226), Expect = 2e-15
Identities = 116/521 (22%), Positives = 217/521 (41%), Gaps = 35/521 (6%)
Frame = -3
Query: 2045 AIATLNDELLNEKDDKKCIVND----RNILEAAKQALEYKVADLEAAKTTLNDELERKKD 1878
++ + +EL EK+ + D + IL+ K A E +A+L+ K+ + E
Sbjct: 3885 SLEKMTEELKREKESFTHLAEDTKKEQEILDEIKVANESLMAELQKEKSNFEEMRENISK 3944
Query: 1877 DNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILI 1698
+ K + R+ + + Q + + KIV +L+ I+
Sbjct: 3945 QTEDVKNKKENLRLREDELGQLQAEIHKQQREIEKEKSNIESERAAIIKIVEDLQHKIIS 4004
Query: 1697 LHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEE---DEVLE 1527
L + + K D+ A + + K + +E + R EE E
Sbjct: 4005 LDRDAESLKLDREAFENEREVLKQMKTELERETDEIEKIKLETQHDRQRVEEMTAQITKE 4064
Query: 1526 RSASNLAIMKAIREEELRKEKDGK-----SALVENGEGCEAEKQGLEKTV---------L 1389
R N I + R++ + EK+ ++ + + E EK LEKT L
Sbjct: 4065 RDKINNLIEETNRKDMVLNEKNRDIEEKIKSIQSDKDMLEKEKHNLEKTRSELYKVKEDL 4124
Query: 1388 ERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKT--VLDLEPTIPSLND 1215
E++ N T+ I +E EK++++ E E E+Q +K + L+ I +L
Sbjct: 4125 EKQKEN--TLAEIQKEREDLEKMNENITIEMHEIKHQEEQMKQKQDELDQLKTEIQNLQQ 4182
Query: 1214 ALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEG--HEAEIERKLEASNLTHNDELHK 1041
L+++ + +M ++ L+ R S+L+ + ++ D E +E ++ K + E+ K
Sbjct: 4183 ELEKEKEIIMKDRSELDLRQSELDKQQTNMNDIIETMKNERKLLDKDKEEMEEQKQEMEK 4242
Query: 1040 EKDDK----KSIMNDLDRVKAEKQVLESKVSDLETTYSTLNNELQQKMDDNEAFLNERDG 873
E+D+ KS+ DL +K +KQV+E + + LE L E + E NER
Sbjct: 4243 ERDNMDQSIKSLDEDLKMMKLQKQVIEEEKNKLEQMKFELQREADEIRKIKEETQNERQS 4302
Query: 872 LEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTL------KKRISELEEAISIL 711
LE + + L K DL + + D+ A K ++ K+ + E+ E IS
Sbjct: 4303 LEKMTKALIKEREDLVHLAEYTKREKEMLDEMQVANKSSMADLQREKRILEEMRENISKQ 4362
Query: 710 TDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLE 588
T+ + + + E+ +LQ ++ K+ E D+EK +E
Sbjct: 4363 TEDIENEKEKSKLREDELKKLQTEVQKQQSE-IDMEKTNIE 4402
Score = 91.7 bits (226), Expect = 2e-15
Identities = 117/514 (22%), Positives = 225/514 (43%), Gaps = 33/514 (6%)
Frame = -3
Query: 2027 DELLNEKDDK-----KCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAI 1863
D +LNE D K I +D+++LE + LE ++L AK L + E ++ D +
Sbjct: 4535 DMVLNEMDRDIEEKIKSIQSDKDMLEKERHNLEKTRSELARAKENLETQREIERKDIEKM 4594
Query: 1862 IKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEEL 1683
KK + + + ++K Q Q+ D + L+ I L +EL
Sbjct: 4595 -KKNISREMHEIKHQEEQMKQKQDE--------------------LDQLKTEIQNLQQEL 4633
Query: 1682 QKEKDD--KTALIKDLVAAEPGKR--TVNEIVSHLESKSRSL-KEHFLREEEDEVLERSA 1518
+KEK+ K DL +E K+ +N+I+ ++++ + L K+ EE+ + +E+
Sbjct: 4634 EKEKEIIMKARSQLDLRQSELDKQQTNMNDIMETMKNERKQLDKDKEETEEQKQEMEKEK 4693
Query: 1517 SNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHEEE 1338
+ + +E+L+ K K + E E K K LER A +E
Sbjct: 4694 HDFDQSRKSLDEDLKMMKLQKQVIEE-----EKSKLKQMKIELEREA-----------DE 4737
Query: 1337 LRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKR 1158
+RK K + T+N E+Q EK L+ L++ +R + K A E
Sbjct: 4738 IRKVKEE----TQN------ERQIFEKMTEALKKEREDLSEDAKRKNQVLDEMKVANEST 4787
Query: 1157 CSDLEAKNASLTDNQEG---HEAEIERKLEASNLTHND------ELHKEKDDKKSIMNDL 1005
+D+ + ++L + +E ++E K E L E+HK++ + + +++
Sbjct: 4788 LADILRERSNLQEMRENISKQTEDVENKKEKIRLREEKLKQLQAEIHKQQSETEKEKSNI 4847
Query: 1004 DRVKAEKQVLESKVSDLETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLE 825
+R E+ + V DL++ +L+ + + D EAF NE++ L+ +K LE+ ++E
Sbjct: 4848 ER---ERAAIIKDVEDLQSKIISLDRDAESLKLDREAFENEKEELKQMKTELEREADEIE 4904
Query: 824 ----ATIHDIEMKTGKDDDYNEA----------EKQTLKKRISELEEAISILTDKAKKLL 687
T H+ + D+ E K+ ++++ E+E+ + K L
Sbjct: 4905 KIKLETQHERQRVEEMTADFMETMNNERKQLNKNKEEMQEQKQEMEKERHDMDQSRKSLD 4964
Query: 686 KDINIWLSEVTELQEDLNKESKEKQDLEKRVLEL 585
K++ + + ++E+ NK + K +LEK E+
Sbjct: 4965 KNLKMMKLQKQVIEEEKNKLEQMKIELEKEADEI 4998
Score = 91.3 bits (225), Expect = 3e-15
Identities = 133/567 (23%), Positives = 248/567 (43%), Gaps = 62/567 (10%)
Frame = -3
Query: 2081 QALESKVSVFEAAIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADL-----EAA 1917
+ LES + + + L +LL + D + + DR +LE K+ L+ DL E
Sbjct: 3639 ELLESDRKLLKKDVENLQQKLLIIESDSESLKQDRELLENEKEVLKQMKTDLQGEAEEIE 3698
Query: 1916 KTTLNDELERKK-DDNNAIIKKA----------LDKRISDLKADAPQRDQEDDMNALIXX 1770
K L + ER++ ++ A I+K + + I D+K Q Q+ D
Sbjct: 3699 KIKLETQHERQRVEEMTAQIQKDREYLQKMNDNITREIHDIKYQEKQMKQKQDE------ 3752
Query: 1769 XXXXXXXXXXXXKIVSNLEVNILILHEELQKEKD----DKTALIKDLVAAEPGKR--TVN 1608
+ L+ I L +EL+KEK+ D++ L DL +E K+ +N
Sbjct: 3753 --------------LDQLKTEIQNLQQELEKEKEIIMKDRSEL--DLKQSELDKQQTNMN 3796
Query: 1607 EIVSHLESKSRSL-KEHFLREEEDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGE 1431
+I+ ++++ + L K+ EE+ +E+ + + +E+L+ K K
Sbjct: 3797 DIIETMKNERKQLDKDKEEMEEQKREIEKEKHDFDQGRNSLDEDLKMMKLQKQVF----- 3851
Query: 1430 GCEAEKQGLE--KTVLERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCE------AE 1275
E EK LE K LER A + + +EE++ E+ +TE + + AE
Sbjct: 3852 --EEEKNKLEQMKIELEREAGEIRKI----KEEIQNERQSLEKMTEELKREKESFTHLAE 3905
Query: 1274 KQGPEKTVLD-LEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAK--NASLTDNQEGH 1104
E+ +LD ++ SL LQ++ ++ + K+ D++ K N L +++ G
Sbjct: 3906 DTKKEQEILDEIKVANESLMAELQKEKSNFEEMRENISKQTEDVKNKKENLRLREDELG- 3964
Query: 1103 EAEIERKLEASNLTHNDELHKEKDDKKSIMNDLDRVKAEKQVLESKVSDLETTYSTLNNE 924
+L+A E+HK++ + I + +++E+ + V DL+ +L+ +
Sbjct: 3965 ------QLQA-------EIHKQQ---REIEKEKSNIESERAAIIKIVEDLQHKIISLDRD 4008
Query: 923 LQQKMDDNEAFLNERDGLEAVKQGLEK-----------------RVLDLEATIHDIEMKT 795
+ D EAF NER+ L+ +K LE+ RV ++ A I K
Sbjct: 4009 AESLKLDREAFENEREVLKQMKTELERETDEIEKIKLETQHDRQRVEEMTAQITKERDKI 4068
Query: 794 GKDDDYNEAEKQTLKKRISELEEAI-SILTDK--AKKLLKDINIWLSEVTELQEDLNKE- 627
+ + L ++ ++EE I SI +DK +K ++ SE+ +++EDL K+
Sbjct: 4069 NNLIEETNRKDMVLNEKNRDIEEKIKSIQSDKDMLEKEKHNLEKTRSELYKVKEDLEKQK 4128
Query: 626 -------SKEKQDLEKRVLELTSKLEK 567
KE++DLEK +T ++ +
Sbjct: 4129 ENTLAEIQKEREDLEKMNENITIEMHE 4155
Score = 89.0 bits (219), Expect = 2e-14
Identities = 123/538 (22%), Positives = 234/538 (43%), Gaps = 24/538 (4%)
Frame = -3
Query: 2081 QALESKVSVFEAAIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLN 1902
Q +E + E A L E + + ++ I NDR E L+ + D+E + +
Sbjct: 2805 QIIEDERDKIEQIKAELQKEAKDTEKQRQDIENDRRNNEEMVIKLQNEKKDIETSTDRIR 2864
Query: 1901 DE-------LERKKDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXX 1743
DE +R + D + + K+ D + K + +D E + +
Sbjct: 2865 DEEANLRVLKQRLESDRDTLEKERFDLK----KTNTEMKDLEKQLESQNRQHEIQLAEIQ 2920
Query: 1742 XXXKIVSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKE 1563
+I+ L++ + E+L+KE+D D+ E E+ E +
Sbjct: 2921 KEREILEQLKLTLSKQKEDLEKERDCFEKEKADISLRE-------ELQEQSEREGIGKTR 2973
Query: 1562 HFLREEEDEVLE------RSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLE 1401
+++E DE+ + + N + K I E+E K + K+ L + E E +++ +E
Sbjct: 2974 VRIKKEMDELKQTRLNVVKELENNELQKQIIEDERDKIEQIKAELQKEAEDTEKQRRDIE 3033
Query: 1400 K---------TVLERRASNLDT-MDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTV 1251
K L+ +++T D I +EE E V K L + + E E+ EKT
Sbjct: 3034 KDRRNNEEMVIKLQNEKKDIETSTDRIRDEEANLE-VQKQRLESDRDTLEKERFDLEKTK 3092
Query: 1250 LDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIE-RKLEA 1074
++ +L L+ + + + ++K LE +L+ +E E E + + E
Sbjct: 3093 TEM----GNLKKQLESQIRQHEIQLVEIQKEREILEQLKINLSKQKEDLEKERDCFEKEK 3148
Query: 1073 SNLTHNDELHKEKDDKKSIMNDLDRVKAEKQVLESKVSDLETTYSTLNNELQQKMDDNEA 894
++++ +++L KE+ +++ I N R+K E LE +L NNELQ+K+ +
Sbjct: 3149 ADISLSEDL-KEQSEREGIDNTRTRIKQEMDELEKTRQNLAKEQE--NNELQKKIIE--- 3202
Query: 893 FLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISI 714
+ERD +E +K L+K EA +E+ +++ N E T K+ E E+++
Sbjct: 3203 --DERDKIEQIKAELKK-----EAEKTKLEL---QNERQNLEEAGTKLKKDRENVESLAE 3252
Query: 713 LTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLELTSKLEKCICGARDGL 540
+ + +L+++ I TE+Q N+ +K+ Q+ RVL K I GA++ L
Sbjct: 3253 ELGRKQVVLENMQI----ETEMQRKANESNKQMQE---RVLIELKKTVTDIAGAKEDL 3303
Score = 88.2 bits (217), Expect = 3e-14
Identities = 122/534 (22%), Positives = 228/534 (42%), Gaps = 35/534 (6%)
Frame = -3
Query: 2042 IATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAI 1863
I+ L + + NEK+ K ++ L+ Q + K+ D+E KT + E A
Sbjct: 5899 ISKLKEYIDNEKEKSKLREDELKKLQTEVQKQQSKI-DME--KTNIESE--------RAA 5947
Query: 1862 IKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEEL 1683
+ + +++LK + D E M ++ + V NL+ ++ L +
Sbjct: 5948 MIREKQNMMTELKKKS--EDVEIQMKEILTEKELLHNDRKLLTRDVENLQQKLIDLERDS 6005
Query: 1682 QKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVL---ERSASN 1512
++ K D+ A + A + K + +E + R EE ER N
Sbjct: 6006 KRLKLDREAFENEKEAMKQMKTDLQIQADEIEKIKLETQHDRQRVEEMAAQIQKERDKIN 6065
Query: 1511 LAIMKAIREEELRKEKDGK-----SALVENGEGCEAEKQGLEKTV---------LERRAS 1374
I + R++ + EK+ ++ + + E E+ LEKT LE++
Sbjct: 6066 NLIEETNRKDMVLNEKNRDIEEKIKSIQSDKDMLEKERHNLEKTRSELYKVKEDLEKQKE 6125
Query: 1373 NLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKT--VLDLEPTIPSLNDALQRD 1200
N T+ I +E EK++++ E E E+Q +K + L+ I +L L+++
Sbjct: 6126 N--TLAEIQKEREDVEKMNENITREMHEIKHQEEQMNQKQDELDQLKTEIQNLQQELEKE 6183
Query: 1199 LDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIER--KLEASNLTHNDELHKEKDD- 1029
+ +M ++ + R S+L+ + ++ D E + E ++ K + E+ KEK D
Sbjct: 6184 KEIIMKDRSQFDLRQSELDKQQTNMNDIMETMKNERKQLDKDKEEMEEQKQEMEKEKHDF 6243
Query: 1028 ---KKSIMNDLDRVKAEKQVLESKVSDLETTYSTLNNELQQKMDDNEAFLNERDGLEAVK 858
+KS+ DL +K +KQV E + + LE L E + E NER LE +
Sbjct: 6244 DQSRKSLDKDLKMMKLQKQVFEEEKNKLEQMKIELEREADEIRKIKEETQNERQSLEKMT 6303
Query: 857 QGLEKRVLDLEATIHDIEMKTGKDDDY-------NE---AEKQTLKKRISELEEAISILT 708
+ L+K + E+ H E T K+ + NE A+ Q K + E+ E IS T
Sbjct: 6304 EELKK---EKESFTHLAE-DTKKEQEILDKVKVANESLMADLQKEKSNLEEMRENISKQT 6359
Query: 707 DKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLELTSKLEKCICGARD 546
+ + +++ + E+ +LQ ++ K+ +E +EK + + S+ I D
Sbjct: 6360 EDVENKKENLRLREDELWQLQAEIYKQQRE---IEKEKINIESERAAIIKNVED 6410
Score = 87.8 bits (216), Expect = 3e-14
Identities = 125/549 (22%), Positives = 249/549 (45%), Gaps = 43/549 (7%)
Frame = -3
Query: 2027 DELLNEKDDK-----KCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAI 1863
D +LNEK+ K I +D+++LE K LE ++L K ++LE++K++ A
Sbjct: 4079 DMVLNEKNRDIEEKIKSIQSDKDMLEKEKHNLEKTRSELYKVK----EDLEKQKENTLAE 4134
Query: 1862 IKKA---LDKRISDLKADAPQ-RDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILIL 1695
I+K L+K ++ + + + QE+ M + L+ I L
Sbjct: 4135 IQKEREDLEKMNENITIEMHEIKHQEEQMKQ--------------KQDELDQLKTEIQNL 4180
Query: 1694 HEELQKEKD----DKTALIKDLVAAEPGKR--TVNEIVSHLESKSRSL-KEHFLREEEDE 1536
+EL+KEK+ D++ L DL +E K+ +N+I+ ++++ + L K+ EE+ +
Sbjct: 4181 QQELEKEKEIIMKDRSEL--DLRQSELDKQQTNMNDIIETMKNERKLLDKDKEEMEEQKQ 4238
Query: 1535 VLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMD 1356
+E+ N+ +E+L+ K K + E E K L++ E R +T +
Sbjct: 4239 EMEKERDNMDQSIKSLDEDLKMMKLQKQVIEEEKNKLEQMKFELQREADEIRKIKEETQN 4298
Query: 1355 AIHEEELRKEKVDKSALTENGEGCE-AEKQGPEKTVLD-LEPTIPSLNDALQRDLDRVMA 1182
E EK+ K+ + E + AE EK +LD ++ S LQR+ +
Sbjct: 4299 ----ERQSLEKMTKALIKEREDLVHLAEYTKREKEMLDEMQVANKSSMADLQREKRILEE 4354
Query: 1181 EKQALEKRCSDLE---AKNASLTDNQEGHEAEIERK-----LEASNLTHN---------- 1056
++ + K+ D+E K+ D + + E++++ +E +N+
Sbjct: 4355 MRENISKQTEDIENEKEKSKLREDELKKLQTEVQKQQSEIDMEKTNIESERAVMIREKQN 4414
Query: 1055 --DELHKEKDD----KKSIMNDLDRVKAEKQVLESKVSDLETTYSTLNNELQQKMDDNEA 894
EL K+ +D K I+ + + ++ + +L+ + DL+ ++ + + D EA
Sbjct: 4415 MMTELKKKSEDVEIQMKEILTEKELLENDSNLLKKDMEDLKQKLMSIERDSESLKLDREA 4474
Query: 893 FLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISI 714
F NE++ L+ +K L+ + ++E I+++T D E + ++K E+ I +
Sbjct: 4475 FGNEKEVLKQMKTDLQIQADEIE----KIKLETQHDRQRVEEKTAQIQKDRDEINNLI-V 4529
Query: 713 LTDKAKKLLKDINIWLSE-VTELQEDLNKESKEKQDLEKRVLELTSKLEKCICGARDGLS 537
T++ +L +++ + E + +Q D + KE+ +LEK EL A++ L
Sbjct: 4530 ETNRKDMVLNEMDRDIEEKIKSIQSDKDMLEKERHNLEKTRSELAR--------AKENLE 4581
Query: 536 TIKEAWMSD 510
T +E D
Sbjct: 4582 TQREIERKD 4590
Score = 87.0 bits (214), Expect = 6e-14
Identities = 104/492 (21%), Positives = 228/492 (46%), Gaps = 21/492 (4%)
Frame = -3
Query: 2012 EKDDKKCIVNDRNI----LEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKALD 1845
EKD K N++N+ L A + L+ + A++E K L + ++R + + I K+
Sbjct: 2487 EKDRLKLQENEQNMQMSQLNAKQNELDERQAEMEKQKRELENVMDRLEKEKVEITKEK-- 2544
Query: 1844 KRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDD 1665
+R+++++ + +++ D+ + ++E + IL+ EL+K K+
Sbjct: 2545 QRVNEMQNEVKRKNASVDL------------IKQEVLREQDHIENSREILNRELEKIKEK 2592
Query: 1664 KTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNLAIMKAIRE 1485
KT L ++ A + K + + + L L ++E E E+ ++ + E
Sbjct: 2593 KTILAEEFEALDDKKEMIGKEMQRLGKMKAEL------QKEAEDTEKQRRDIDNDRRNNE 2646
Query: 1484 EELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHEEELRKEKVDKSAL 1305
E + K ++ K + + + E+ L + +R S+ DT++ +L K K + L
Sbjct: 2647 EMVIKLQNEKKDIETSTDRIRDEEANL-RVQKQRLESDRDTLEK-ERFDLEKTKTEMKDL 2704
Query: 1304 TENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASL 1125
+ + E Q + + +E I + L++ + +K+ LEK E + A +
Sbjct: 2705 EK-----QLESQSRQHEIQLVE--IQKEREILEQLKINLSKQKEDLEKERDCFEKEKADI 2757
Query: 1124 TDNQEGHEAEIERKLEASNLTHNDELHKEKDDKKSIMNDLDRVKAEKQVLESKVSDLETT 945
+ +E E + ++ + + E+ + + + +++ +L+ + +KQ++E + +E
Sbjct: 2758 SLREELEEQSEKEGIDKTRVRIKQEMDELEQTRLNVVKELENNELQKQIIEDERDKIE-- 2815
Query: 944 YSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTG--KDDDYN- 774
+ ELQ++ D E +R +E ++ E+ V+ L+ DIE T +D++ N
Sbjct: 2816 --QIKAELQKEAKDTE---KQRQDIENDRRNNEEMVIKLQNEKKDIETSTDRIRDEEANL 2870
Query: 773 -------EAEKQTLKKRISELEEAISILTDKAKKL---LKDINIWLSEVTELQEDLNK-- 630
E+++ TL+K +L++ + + D K+L + I L+E+ + +E L +
Sbjct: 2871 RVLKQRLESDRDTLEKERFDLKKTNTEMKDLEKQLESQNRQHEIQLAEIQKEREILEQLK 2930
Query: 629 --ESKEKQDLEK 600
SK+K+DLEK
Sbjct: 2931 LTLSKQKEDLEK 2942
Score = 85.9 bits (211), Expect = 1e-13
Identities = 115/526 (21%), Positives = 234/526 (44%), Gaps = 34/526 (6%)
Frame = -3
Query: 2042 IATLNDELLNEKDDKKCIV----NDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDD 1875
+A L+ EL KD+ + I +R+ +E + L ++ +E + D+ ++
Sbjct: 9987 MADLSRELQKAKDELEKIAYKTNKERHEVEQMQAELHSQIQAIEQQGQIMQDKQNHLEEK 10046
Query: 1874 NNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVN---- 1707
+I +K + +I + + Q +QE N L I N + N
Sbjct: 10047 ELSIQRKEEEIKIGNTEF---QIEQEHLNNVLEETNKRQHDLEVMRADIELNKQKNNKDF 10103
Query: 1706 --ILILHEELQKEKDD--------KTALIKDLVAAEPGKRTVNEIVSHLESK-SRSLKEH 1560
+ + EL+ EK D K + L E K + ++ L+SK ++ KE
Sbjct: 10104 ELLEKIRSELENEKYDLQIWTEQQKHLVEVQLQELEKEKERLEKMEIELQSKREQTEKEK 10163
Query: 1559 FLREEEDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLE--KTVLE 1386
+ ++R + + + + + + K+ L E E + E++ LE K +++
Sbjct: 10164 ADLNRVNAEIQREKQVIDKKRHMTNRAMEELETIKTELKERQEKIQTEQEKLEEEKLLVQ 10223
Query: 1385 RRASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDA-- 1212
A NL+ + + + K ++ ++ L E CE ++ E+ D+E I + +A
Sbjct: 10224 IEAENLNKVLEEIKRQQEKLEISEADLKVMKEQCENAREETERKKCDIEEQIQNNENAKH 10283
Query: 1211 -LQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEI--ERKL--EASN--LTHND 1053
L+++ + +KQ L+K+ DL+ + + +N E + + E+KL + +N L D
Sbjct: 10284 LLEQERKDIDKQKQELQKQADDLDMRMIAHRENVEMSKRSLDEEKKLLEQKANEILRQRD 10343
Query: 1052 ELHKEKDDKKSIMNDLDRVKAEKQVLESKVSDLETTYSTLNNEL---QQKMDDNEAFLNE 882
+L KEK+D N LD ++ E Q + +++ NE+ QQ+++++ +NE
Sbjct: 10344 DLEKEKEDMMKKWNKLDVLQNEMQNENKAMEEIKYELDGKRNEINKEQQRLEESLRAINE 10403
Query: 881 RDG-LEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTD 705
G LE ++ EK+ +E + +M E++ L + SELE+ + +
Sbjct: 10404 EKGDLEIMRADYEKQEQQIEEMRVEAKM-----------ERKELDQIKSELEKDKTEIDY 10452
Query: 704 KAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLELTSKLEK 567
+ KKL D N+ E +L++ ++ ++Q +E EL K+++
Sbjct: 10453 EWKKLNNDRNMIEKERNDLEKMKSELMTQRQQMEDERSELDQKIKE 10498
Score = 85.5 bits (210), Expect = 2e-13
Identities = 111/536 (20%), Positives = 235/536 (43%), Gaps = 46/536 (8%)
Frame = -3
Query: 2072 ESKVSVFEAAIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDEL 1893
E+K ++ E +E+ EK+ ++ R +E ++ +E + LE ++ ++ E
Sbjct: 12356 ETKANILEMKTKAEPEEIKKEKEKEEEEQEMRVKVEMERKEIEQIKSQLERVRSEMDHEQ 12415
Query: 1892 ERKKDDNNAII--KKALDKRISDLKADAPQRDQE-DDMNALIXXXXXXXXXXXXXXKIVS 1722
++ DD I K+ L+K S++ Q ++E +++ I +IV
Sbjct: 12416 KKLNDDKKMIEQEKEDLEKMKSEIMKQRQQMEEERSELDKKIKQTDLEKHDIENSKEIVE 12475
Query: 1721 NLEVNILILHEELQKEK-----------DDKTALIKDLVAAEPGKRTVNEIVSHLESKSR 1575
L V + E+Q +K D++ LI++ + + + E+ ++ +
Sbjct: 12476 KLMVEVEKQKHEIQFQKEELDIERQKIADEQDLLIQNKIEQQNENERIKEMDEEIKKERE 12535
Query: 1574 SLKEHFL-----REEEDEVLE---RSASNLAIMKAIREEELRKEKDGKSALVENGEGCEA 1419
+LKE + +EE + V+E R +L M E+ + + + L + E
Sbjct: 12536 TLKEMEVNLQKEKEEIESVIEETQRRKEDLEKMSTDINEQKQDLMNQRDLLKQ-----ER 12590
Query: 1418 EKQGLEKTVLERRASNLDTMDAI-----------HEEELRKEKVDKSALTENGEGCEAEK 1272
E+ + T L++R +T I +E+L++ + ++ E E
Sbjct: 12591 EEMNHKLTQLQQRIDEFETTSNILVTTKMEEKTEMDEKLQQAIKEYESIIEETNRKRTEL 12650
Query: 1271 QGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEI 1092
+ E + ++ D L+++ E++ L+K+ DLE + D +E + +
Sbjct: 12651 EEIEVDQSQQNKNVETMKDLLEKERKDTEKEREELQKQADDLEMQMIEHGDKEEMSKRSL 12710
Query: 1091 --ERKL--EASN--LTHNDELHKEKDDKKSIMNDLDRVKAEKQVLESKVSDLETTYSTLN 930
E+KL + +N L D+L KEK+D N+LD ++ E Q ++++ +++ T
Sbjct: 12711 DEEKKLLEQKANEILRQRDDLEKEKEDMMKKWNELDGLQKEIQNQKNEMEEIKCELETKR 12770
Query: 929 NELQQKMDDNEAFLN----ERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKD-DDYNEAE 765
E+ ++ E LN ER LE V+ EK + I ++ +KT + D+ ++
Sbjct: 12771 IEIIKEQKRLEESLNTVNEERQYLEIVRVDYEKH----QQQIEEMRVKTKMERDELDQLM 12826
Query: 764 KQTL--KKRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLE 603
+ L +K ++ I +L + ++ +++ ++ EL+ + K EK+DLE
Sbjct: 12827 AKMLMDRKENERSKDMIGLLKKEMEQTKFNLD---AQEEELKLEKQKIQNEKKDLE 12879
Score = 84.7 bits (208), Expect = 3e-13
Identities = 119/558 (21%), Positives = 246/558 (44%), Gaps = 48/558 (8%)
Frame = -3
Query: 2075 LESKVSVFEAAIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDE 1896
L+ + S + +ND + K+++K + D+ E KQ +E + D + ++ +L+++
Sbjct: 5324 LDLRQSELDKQQTNVNDIMETMKNERKQLDKDKEETEEQKQEMEKEKHDFDQSRKSLDED 5383
Query: 1895 LERKKDDNNAII--KKALDKRISDLKADAPQ--RDQEDDMNALIXXXXXXXXXXXXXXKI 1728
L+ K + K L++ +L+ +A + + +E+ N +
Sbjct: 5384 LKMMKLQKQVLEDEKSKLEQMKIELEREAVEIRKIKEEIQNERQNLEKMTEALKEEREDL 5443
Query: 1727 VSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLK--EHFL 1554
+ N +L E + ++++ E + +++ +E+K +L+ E L
Sbjct: 5444 AEETKKNNQVLDEMKVANESTLADILREKSNLEEMRENISKQTEDVENKKENLRLREDEL 5503
Query: 1553 REEEDEV------LERSASNL-----AIMKAIREEELR---KEKDGKSALVENGEGCEAE 1416
R+ + E+ +E+ N+ AI+K + + + + ++D +S ++ E E E
Sbjct: 5504 RQLQAEIHKQQREIEKEKINIESERAAIIKDVEDLQHKIICLDRDAESLKLDR-EAFENE 5562
Query: 1415 KQGLE--KTVLERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCEA----EKQGPEKT 1254
K+ L+ KT LER A ++ + E + +++V++ A + E E+ +
Sbjct: 5563 KEVLKQMKTELEREADEIEKIKL--ETQHDRQRVEEMAAQIQKDRDEINNLIEETNRKDM 5620
Query: 1253 VL-----DLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIE 1089
VL D+E I S+ Q D D + EK LEK S+L L +E AEI+
Sbjct: 5621 VLNEKNRDIEEKIKSI----QSDKDMLEKEKHDLEKTRSELYKVKEDLEKQKENTLAEIQ 5676
Query: 1088 RKLEA-----SNLT-------HNDELHKEKDD-----KKSIMNDLDRVKAEKQVLESKVS 960
++ E N+T H +E +K D K I N ++ EK+++ S
Sbjct: 5677 KEREDLEKMNENITREMHEIKHQEEQMNQKQDELDQLKTEIQNLQQELEKEKEIIMKDRS 5736
Query: 959 DLETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDD 780
L+ S L+ + D E NER L+ K+ +E++ ++E +++ D+
Sbjct: 5737 QLDLRQSELDKQQTNMNDIMETMKNERKQLDKDKEEMEEQKQEMEKERDNMDQSRKSLDE 5796
Query: 779 YNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEK 600
+ +K L+K++ E E+ +K +++ ++ E+++++E+ ++Q LEK
Sbjct: 5797 --DQKKMKLQKQMFEEEK------NKLEQMKIELEREADEISKIKEE---TQNKRQRLEK 5845
Query: 599 RVLELTSKLEKCICGARD 546
EL + E A D
Sbjct: 5846 MTEELIREKESLAHLAED 5863
Score = 84.0 bits (206), Expect = 5e-13
Identities = 103/498 (20%), Positives = 216/498 (43%), Gaps = 12/498 (2%)
Frame = -3
Query: 2075 LESKVSVFEAAIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDE 1896
L+ + S + +ND + K+++K + D+ E KQ +E + D + ++ +L+++
Sbjct: 4647 LDLRQSELDKQQTNMNDIMETMKNERKQLDKDKEETEEQKQEMEKEKHDFDQSRKSLDED 4706
Query: 1895 LERKKDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNL 1716
L+ K + K+ +++ S LK + ++E D + N
Sbjct: 4707 LKMMK-----LQKQVIEEEKSKLKQMKIELEREADEIRKVKEE-------------TQNE 4748
Query: 1715 EVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEED- 1539
+ E L+KE++D +E KR N+++ ++ + S LRE +
Sbjct: 4749 RQIFEKMTEALKKERED---------LSEDAKRK-NQVLDEMKVANESTLADILRERSNL 4798
Query: 1538 -EVLERSASNLAIMKAIREE-ELRKEKDGKSALVENGEGCEAEKQGLEKTVLER-RASNL 1368
E+ E + ++ +E+ LR+EK + + + E EK EK+ +ER RA+ +
Sbjct: 4799 QEMRENISKQTEDVENKKEKIRLREEKLKQLQAEIHKQQSETEK---EKSNIERERAAII 4855
Query: 1367 DTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRV 1188
++ + + + ++ D +L + E E EK+ ++ +LE +++++
Sbjct: 4856 KDVEDLQSKIISLDR-DAESLKLDREAFENEKEELKQMKTELEREAD--------EIEKI 4906
Query: 1187 MAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASNLTHNDELHKEKDDKKSIMND 1008
E Q +R ++ A +N+ + + +++ E H +KS+ +
Sbjct: 4907 KLETQHERQRVEEMTADFMETMNNERKQLNKNKEEMQEQKQEMEKERHDMDQSRKSLDKN 4966
Query: 1007 LDRVKAEKQVLESKVSDLETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDL 828
L +K +KQV+E + + LE L E + E NER LE + + L+K
Sbjct: 4967 LKMMKLQKQVIEEEKNKLEQMKIELEKEADEIRKIKEETQNERQRLEKMTEELKKEKESF 5026
Query: 827 EATIHDI--------EMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLLKDINI 672
D +MK + + +K+ K + E+ E IS T+ ++K + I +
Sbjct: 5027 THLAEDTKTEKKILDKMKVANESLMADLQKE--KSNLEEMRENISKQTEDSEKEKEKIRL 5084
Query: 671 WLSEVTELQEDLNKESKE 618
E+ +LQ +++K+ E
Sbjct: 5085 REDELEQLQAEIHKQQGE 5102
Score = 83.6 bits (205), Expect = 7e-13
Identities = 126/569 (22%), Positives = 237/569 (41%), Gaps = 71/569 (12%)
Frame = -3
Query: 2081 QALESKVSVFEAAIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLN 1902
Q LE + S E L E + + K+ I N+R LE +AL+ + DL N
Sbjct: 5392 QVLEDEKSKLEQMKIELEREAVEIRKIKEEIQNERQNLEKMTEALKEEREDLAEETKKNN 5451
Query: 1901 DELERKKDDNNAIIKKALDKR---------ISDLKADAPQRDQ-----EDDMNALIXXXX 1764
L+ K N + + L ++ IS D + + ED++ L
Sbjct: 5452 QVLDEMKVANESTLADILREKSNLEEMRENISKQTEDVENKKENLRLREDELRQLQAEIH 5511
Query: 1763 XXXXXXXXXXKIVSNLEVNILILHEELQKE----KDDKTALIKDLVAAEPGKRTVNEIVS 1596
+ + I+ E+LQ + D +L D A E K + ++ +
Sbjct: 5512 KQQREIEKEKINIESERAAIIKDVEDLQHKIICLDRDAESLKLDREAFENEKEVLKQMKT 5571
Query: 1595 HLESKSRSLKEHFLREEEDEVL----------ERSASNLAIMKAIREEELRKEKDGK--- 1455
LE ++ +++ L + D +R N I + R++ + EK+
Sbjct: 5572 ELEREADEIEKIKLETQHDRQRVEEMAAQIQKDRDEINNLIEETNRKDMVLNEKNRDIEE 5631
Query: 1454 --SALVENGEGCEAEKQGLEKTV---------LERRASNLDTMDAIHEEELRKEKVDKSA 1308
++ + + E EK LEKT LE++ N T+ I +E EK++++
Sbjct: 5632 KIKSIQSDKDMLEKEKHDLEKTRSELYKVKEDLEKQKEN--TLAEIQKEREDLEKMNENI 5689
Query: 1307 LTENGEGCEAEKQGPEKT--VLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKN 1134
E E E+Q +K + L+ I +L L+++ + +M ++ L+ R S+L+ +
Sbjct: 5690 TREMHEIKHQEEQMNQKQDELDQLKTEIQNLQQELEKEKEIIMKDRSQLDLRQSELDKQQ 5749
Query: 1133 ASLTDNQEGHEAEIER--KLEASNLTHNDELHKEKDD----KKSIMNDLDRVKAEKQVLE 972
++ D E + E ++ K + E+ KE+D+ +KS+ D ++K +KQ+ E
Sbjct: 5750 TNMNDIMETMKNERKQLDKDKEEMEEQKQEMEKERDNMDQSRKSLDEDQKKMKLQKQMFE 5809
Query: 971 SKVSDLETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGL----------------EKR 840
+ + LE L E + E N+R LE + + L EK+
Sbjct: 5810 EEKNKLEQMKIELEREADEISKIKEETQNKRQRLEKMTEELIREKESLAHLAEDTKTEKK 5869
Query: 839 VLDLEATIHDIEMKTGKDDDYNEAEK-----QTLKKRISELEEAISILTDKAKKLLKDIN 675
+LD EMK + + ++ + +++ IS+L+E I +K K L++
Sbjct: 5870 ILD--------EMKVANESSMADLQREKSILEEMRENISKLKEYID--NEKEKSKLRE-- 5917
Query: 674 IWLSEVTELQEDLNKESKEKQDLEKRVLE 588
E+ +LQ ++ K+ + K D+EK +E
Sbjct: 5918 ---DELKKLQTEVQKQ-QSKIDMEKTNIE 5942
Score = 83.2 bits (204), Expect = 9e-13
Identities = 116/555 (20%), Positives = 242/555 (43%), Gaps = 19/555 (3%)
Frame = -3
Query: 1979 RNILEAAKQALEYKVADLEAAKTTLND---ELERKKDDNNAIIKKALDKRISDLKADAPQ 1809
R LE + L+Y ++ K L EL+R+ DD + +K ++R S K
Sbjct: 3455 RTALEVEMKELKYHKQAIQEEKNKLQQMKIELQREADDIKKLKEKTRNERQSLEKMAENL 3514
Query: 1808 RDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHE----ELQKEKDDKTALIKDL 1641
++DD+ L + + +LHE ++QKEK + + + +
Sbjct: 3515 EKEKDDLAHLAED--------------TKRKDDEMKVLHESALADIQKEKCNLEQMRESM 3560
Query: 1640 VAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNLAIMKAIREEE----LR 1473
NE++ E K L+E L++ + E+ R + + K+I E E +
Sbjct: 3561 FKQ-------NEMIDS-EKKKMILREDKLQQMQAEI-NRQQTEMDTKKSIIENERAAMTK 3611
Query: 1472 KEKDGKSALVENGEGCEAEKQGL--EKTVLERRASNLDTMDAIHEEELRKEKVDKSALTE 1299
K +D + L + E E + + + EK +LE L +++L + D +L +
Sbjct: 3612 KNQDLMTELTKQSEDVEIQMKEVLTEKELLESDRKLLKKDVENLQQKLLIIESDSESLKQ 3671
Query: 1298 NGEGCEAEKQGPEKTVLDLE---PTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNAS 1128
+ E E EK+ ++ DL+ I + Q + RV ++K L+ N +
Sbjct: 3672 DRELLENEKEVLKQMKTDLQGEAEEIEKIKLETQHERQRVEEMTAQIQKDREYLQKMNDN 3731
Query: 1127 LTDNQEGHEAEIERKLEASNLTHNDELHKEKDDKKSIMNDLDRVKAEKQVLESKVSDLET 948
+T +E H+ + + K DEL + K + +++ +L++ EK+++ S+L+
Sbjct: 3732 IT--REIHDIKYQEKQMKQK---QDELDQLKTEIQNLQQELEK---EKEIIMKDRSELDL 3783
Query: 947 TYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEM-KTGKDDDYN- 774
S L+ + D E NER L+ K+ +E++ ++E HD + + D+D
Sbjct: 3784 KQSELDKQQTNMNDIIETMKNERKQLDKDKEEMEEQKREIEKEKHDFDQGRNSLDEDLKM 3843
Query: 773 -EAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKR 597
+ +KQ ++ ++LE+ + I ++ ++ I + + E + +E K +++
Sbjct: 3844 MKLQKQVFEEEKNKLEQ-MKIELEREAGEIRKIKEEIQNERQSLEKMTEELKREKESFTH 3902
Query: 596 VLELTSKLEKCICGARDGLSTIKEAWMSDCMVPDNWVPFEDLVQGFSRKTSPLDITKTCD 417
+ E T K ++ + D + E+ M++ + FE++ + S++T D+ +
Sbjct: 3903 LAEDTKKEQEIL----DEIKVANESLMAELQKEKS--NFEEMRENISKQTE--DVKNKKE 3954
Query: 416 AVDISEDSTTNIQVD 372
+ + ED +Q +
Sbjct: 3955 NLRLREDELGQLQAE 3969
Score = 81.3 bits (199), Expect = 3e-12
Identities = 112/514 (21%), Positives = 217/514 (42%), Gaps = 22/514 (4%)
Frame = -3
Query: 2042 IATLNDELLNEKDDKKC-----------IVNDRNILEAAKQALEYKVADLEAAKTTLNDE 1896
I+ +++ NEK+ K + ++ ++ K +E + A + K + E
Sbjct: 4359 ISKQTEDIENEKEKSKLREDELKKLQTEVQKQQSEIDMEKTNIESERAVMIREKQNMMTE 4418
Query: 1895 LERKKDDNNAIIKKAL-DKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSN 1719
L++K +D +K+ L +K + + ++ ++D ED L+ +
Sbjct: 4419 LKKKSEDVEIQMKEILTEKELLENDSNLLKKDMEDLKQKLMSIERDSESLKLDREAFGNE 4478
Query: 1718 LEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEED 1539
EV + + +LQ + D+ + K + + ++ V E + ++ K R E +
Sbjct: 4479 KEV-LKQMKTDLQIQADE---IEKIKLETQHDRQRVEEKTAQIQ-KDRD-------EINN 4526
Query: 1538 EVLERSASNLAIMKAIR--EEELRKEKDGKSALVENGEGCEAEKQGLEKT--VLERRASN 1371
++E + ++ + + R EE+++ + K L E E+ LEKT L R N
Sbjct: 4527 LIVETNRKDMVLNEMDRDIEEKIKSIQSDKDML-------EKERHNLEKTRSELARAKEN 4579
Query: 1370 LDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDR 1191
L+T I +++ K K + S + E + + + + L+ I +L L+++ +
Sbjct: 4580 LETQREIERKDIEKMKKNISREMHEIKHQEEQMKQKQDELDQLKTEIQNLQQELEKEKEI 4639
Query: 1190 VMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIER--KLEASNLTHNDELHKEKDD---- 1029
+M + L+ R S+L+ + ++ D E + E ++ K + E+ KEK D
Sbjct: 4640 IMKARSQLDLRQSELDKQQTNMNDIMETMKNERKQLDKDKEETEEQKQEMEKEKHDFDQS 4699
Query: 1028 KKSIMNDLDRVKAEKQVLESKVSDLETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGL 849
+KS+ DL +K +KQV+E + S L+ L E + E NER E + + L
Sbjct: 4700 RKSLDEDLKMMKLQKQVIEEEKSKLKQMKIELEREADEIRKVKEETQNERQIFEKMTEAL 4759
Query: 848 EKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIW 669
+K DL D + K D+ A + TL DI
Sbjct: 4760 KKEREDLS---EDAKRKNQVLDEMKVANESTLA----------------------DI--- 4791
Query: 668 LSEVTELQEDLNKESKEKQDLEKRVLELTSKLEK 567
L E + LQE SK+ +D+E + ++ + EK
Sbjct: 4792 LRERSNLQEMRENISKQTEDVENKKEKIRLREEK 4825
Score = 80.9 bits (198), Expect = 4e-12
Identities = 119/523 (22%), Positives = 221/523 (42%), Gaps = 20/523 (3%)
Frame = -3
Query: 2075 LESKVSVFEAAIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDE 1896
L++ S E + +L E N +D+K + R+ + + A+ + DLE + E
Sbjct: 9663 LQNMKSNLERQLESLRHEKANVEDEKNALEKMRSESKEIQNAIRKEREDLENCWVEIEGE 9722
Query: 1895 LERKKDDNNAI------IKKALDKRISDLKADAPQRDQE--DDMNALIXXXXXXXXXXXX 1740
+R +++ + IKK +D + + + R+++ + M L+
Sbjct: 9723 KKRMEEETRRLEMHREEIKK-VDSELQKSRENIESREEKINNKMEELLQMKVEMGRTKEE 9781
Query: 1739 XXKIVSNLEVNILILHE---ELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSL 1569
K L+ + L E+Q++ +DK I D+ E + EI L+ +++ L
Sbjct: 9782 IEKESQRLQDATIDLENAKAEIQRQ-EDKFEDIIDIKIQEKER----EIKIQLDKETKRL 9836
Query: 1568 KEHFLREEEDEVLE-----RSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGL 1404
E + +D +E R + K + E+E ++ K K L + EKQ
Sbjct: 9837 SEEIELKVKDLEMEMADMKRQKQEIEDTKGLLEKEKQELKQEKKELEDQMMDLTREKQET 9896
Query: 1403 EKTVLERRASNLDTMDAIHEEELRKEKV--DKSALTENGEGCEAEKQGPEKTVLDLEPTI 1230
E+ A D E E+ KEK+ +KS + E +++ ++T + +
Sbjct: 9897 EEERNNLMALKNQLEDLRKENEIVKEKLTLEKSNIEEMQLKIFKQQRLNDQTREENKKE- 9955
Query: 1229 PSLNDALQRDLDRVMAEKQALEKRCSDL-EAKNASLTDNQEGHEAEIERKLEASNLTHND 1053
++L++ +KQ LE + + E KN ++E +A+ E LE N
Sbjct: 9956 ---KESLEQQRFETEQQKQMLEISTTKMMEEKNEMADLSRELQKAKDE--LEKIAYKTNK 10010
Query: 1052 ELHKEKDDKKSIMNDLDRVKAEKQVLESKVSDLETTYSTLNNELQQKMDDNEAFLNERDG 873
E H+ + + + + + ++ + Q+++ K + LE ++ + ++ N F E++
Sbjct: 10011 ERHEVEQMQAELHSQIQAIEQQGQIMQDKQNHLEEKELSIQRKEEEIKIGNTEFQIEQEH 10070
Query: 872 LEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKK 693
L V + KR DLE DIE+ K N + + L+K SELE
Sbjct: 10071 LNNVLEETNKRQHDLEVMRADIELNKQK----NNKDFELLEKIRSELENE---------- 10116
Query: 692 LLKDINIWLSEVTELQE-DLNKESKEKQDLEKRVLELTSKLEK 567
D+ IW + L E L + KEK+ LEK +EL SK E+
Sbjct: 10117 -KYDLQIWTEQQKHLVEVQLQELEKEKERLEKMEIELQSKREQ 10158
Score = 80.1 bits (196), Expect = 7e-12
Identities = 122/570 (21%), Positives = 236/570 (41%), Gaps = 68/570 (11%)
Frame = -3
Query: 2075 LESKVSVFEAAIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLE--AAKTTLN 1902
+E+K + L D+ + K+D+ D LE ++ L + DLE +
Sbjct: 9479 METKKRSLDRMSRELQDDKIRLKNDRDAYEKDMTHLELKREELVRETEDLERKILQQREQ 9538
Query: 1901 DELERKKDDNNA---------IIKK-----------------------ALDKRISDLKAD 1818
DE+ ++ +N I+KK AL + S+L+
Sbjct: 9539 DEMAKRDIENQTEALEVMKVDILKKRNEFAKEMENVHSERQKLLLLQGALQSQESELENR 9598
Query: 1817 APQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDKTALIKDLV 1638
+Q+ A + + + L EELQ+EK ++ + K+ +
Sbjct: 9599 VFMEEQKHLKQAKAETEECRKQLAEMSETVTTE-QNEYRKLIEELQREK-EQLEISKNQI 9656
Query: 1637 AAEPGKRTVNEIVSHLESKSRSLK-EHFLREEEDEVLERSAS-NLAIMKAIREEELRKEK 1464
E K+ + + S+LE + SL+ E E+E LE+ S + I AIR+E
Sbjct: 9657 EQE--KKDLQNMKSNLERQLESLRHEKANVEDEKNALEKMRSESKEIQNAIRKER----- 9709
Query: 1463 DGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHEEELRKEKVDKSALTENGEGC 1284
E+ E C E +G EK +E L+ +H EE++K + EN E
Sbjct: 9710 -------EDLENCWVEIEG-EKKRMEEETRRLE----MHREEIKKVDSELQKSRENIESR 9757
Query: 1283 EAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTD----N 1116
E + + +L ++ + + ++++ R+ LE ++++ + D
Sbjct: 9758 EEKINNKMEELLQMKVEMGRTKEEIEKESQRLQDATIDLENAKAEIQRQEDKFEDIIDIK 9817
Query: 1115 QEGHEAEIERKLEASNLTHNDELHKEKDDKKSIMNDLDRVKAE----KQVLESKVSDLET 948
+ E EI+ +L+ ++E+ + D + M D+ R K E K +LE + +L+
Sbjct: 9818 IQEKEREIKIQLDKETKRLSEEIELKVKDLEMEMADMKRQKQEIEDTKGLLEKEKQELKQ 9877
Query: 947 TYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLE---------KRVLDLE-ATIHDIEMK 798
L +++ + + ER+ L A+K LE K L LE + I ++++K
Sbjct: 9878 EKKELEDQMMDLTREKQETEEERNNLMALKNQLEDLRKENEIVKEKLTLEKSNIEEMQLK 9937
Query: 797 TGKDD-------DYNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQED 639
K + N+ EK++L+++ E E+ +L K++++ N ELQ+
Sbjct: 9938 IFKQQRLNDQTREENKKEKESLEQQRFETEQQKQMLEISTTKMMEEKNEMADLSRELQKA 9997
Query: 638 LN-------KESKEKQDLEKRVLELTSKLE 570
+ K +KE+ ++E+ EL S+++
Sbjct: 9998 KDELEKIAYKTNKERHEVEQMQAELHSQIQ 10027
Score = 79.3 bits (194), Expect = 1e-11
Identities = 93/521 (17%), Positives = 226/521 (43%), Gaps = 46/521 (8%)
Frame = -3
Query: 1991 IVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKALDKR--------- 1839
++N R++L+ ++ + +K L+ + ++ ++K+++ KK ++R
Sbjct: 12024 LMNQRDLLKQEREEINHKWTQLQQRIDEFDAQVSKQKEEDLTKQKKMEEERKSLEETKIK 12083
Query: 1838 ISDLKADAP--------QRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEEL 1683
I ++K ++++E+ M A + I S LE + E
Sbjct: 12084 IIEMKTKTEPEKIKKEKEKEEEEVMRAKVEMKKEELDQ------IKSQLERVRSEIDHEQ 12137
Query: 1682 QKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNLAI 1503
+K DDK + ++ E K + + +E + RS E+ +R+ E + S +
Sbjct: 12138 KKLNDDKKMIEQEKEDLEKMKSEIMKQRQQMEEE-RSELENKIRQTYIEKCDIENSKEIV 12196
Query: 1502 MKAIREEELRKEK----------------DGKSALVENGEGCEAEKQGLEKT--VLERRA 1377
K + E E +K + D + L++N + E + ++ V+++
Sbjct: 12197 QKLMVEVEEQKHEIQFQKEELDIERQKIADEQDLLIQNKSELQNENERIKNINEVIKKER 12256
Query: 1376 SNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDL 1197
L M+A L KEK + ++TE + + + + + + + S D L+++
Sbjct: 12257 ETLKEMEAY----LEKEKEEMKSITEETRRQKEDLEKMSTHINEQKQDLRSQRDLLEQER 12312
Query: 1196 DRVMAEKQALEKRCSDLEA-----------KNASLTDNQEGHEAEIERKLEASNLTHNDE 1050
+ + + + L++R + +A K + ++++ E LE +E
Sbjct: 12313 EEINHKWKQLQQRIDEFDAQVSKQKEEDLPKEKEMKEDRKSLEETKANILEMKTKAEPEE 12372
Query: 1049 LHKEKDDKKSIMNDLDRVKAEKQVLESKVSDLETTYSTLNNELQQKMDDNEAFLNERDGL 870
+ KEK+ ++ +V+ E++ +E S LE S +++E ++ DD + E++ L
Sbjct: 12373 IKKEKEKEEEEQEMRVKVEMERKEIEQIKSQLERVRSEMDHEQKKLNDDKKMIEQEKEDL 12432
Query: 869 EAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKL 690
E +K + K+ +E +++ K K D + + + K+ + +L + + +
Sbjct: 12433 EKMKSEIMKQRQQMEEERSELDKKI-KQTDLEKHDIENSKEIVEKLMVEVEKQKHEIQFQ 12491
Query: 689 LKDINIWLSEVTELQEDLNKESKEKQDLEKRVLELTSKLEK 567
++++I ++ + Q+ L + E+Q+ +R+ E+ +++K
Sbjct: 12492 KEELDIERQKIADEQDLLIQNKIEQQNENERIKEMDEEIKK 12532
Score = 79.0 bits (193), Expect = 2e-11
Identities = 115/572 (20%), Positives = 246/572 (43%), Gaps = 91/572 (15%)
Frame = -3
Query: 2027 DELLNEKDDKKCIVND----RNILEAAKQALEYKVADLEAAKTTLND----------ELE 1890
+EL E+ D + D +N L+ K A E +ADL+ K+ L + ++E
Sbjct: 6721 EELKKERKDVAHLAEDTKREKNSLDEMKVANESSMADLQKEKSNLEEMKENISKQTEDIE 6780
Query: 1889 RKKD------DNNAIIKKALDKRISDLKADAPQRDQE--------DDMNALIXXXXXXXX 1752
++KD D ++ + K+ S+ + + ++E +D+ + I
Sbjct: 6781 KEKDKIRLREDELEQLQAEIHKQQSETEIEKSNIERERAAIIKDVEDLQSKIISLDRDAE 6840
Query: 1751 XXXXXXKIVSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSH----LES 1584
+ N + + + EL++E D+ + K + + ++ V E+ + + +
Sbjct: 6841 SLKLDREAFENEKEELKQMKTELEREADE---IEKIKLETQHERQRVEEMTADFMETMNN 6897
Query: 1583 KSRSL-KEHFLREEEDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQG 1407
+ + L K + EE+ + +E+ ++ + +E+L+ K K L E E K G
Sbjct: 6898 ERKQLDKNKVMIEEQKQEMEKKRDDMDQSRKSLDEDLKMMKAQKQVLEEEKNKLEQMKIG 6957
Query: 1406 LE---------KTVLERRASNLDTM-DAIHEE------ELRKEKVDKSALTENGEGCEAE 1275
LE K + NL+ M +A+ EE E++++ + E A+
Sbjct: 6958 LEREADEISKIKEETQNERQNLEKMANALKEEREYLAEEIKRKNQVLDKIKVANESTLAD 7017
Query: 1274 KQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAE 1095
Q ++ + ++ I + ++ + ++ + L+K ++++ + + + + E+E
Sbjct: 7018 LQKEKRILEEMRENISKQIEDIENEKEKSKLREDELKKLQTEVQKQQSEIDMEKTNIESE 7077
Query: 1094 IERKL-EASNLTHNDELHKEKDD----KKSIMNDLDRVKAEKQVLESKVSDLETTYSTLN 930
+ E N+ EL K+ +D K I+ + + + ++ +L+ V DL+ ++
Sbjct: 7078 RAAMIREKQNMM--TELKKKSEDVEMQMKEILTEKELLHNDRNLLKKDVEDLQQKLMSIE 7135
Query: 929 NELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLE----ATIHD---IEMKTGK------ 789
+ + D EAF NE++ ++ +K L+ + ++E T H+ +E KT +
Sbjct: 7136 RDSESLKLDKEAFENEKEAMKQMKTDLQIQADEIEKIKLETHHERQRVEEKTAQIQKERE 7195
Query: 788 ----------------DDDYNE--AEKQTLKKRISELEEAISILTDKAKKLLKDINIWLS 663
D+ Y E EK+ ++ S+LE+A S + K K+I I L+
Sbjct: 7196 EINTLVEEIKKKRDIIDESYTEIRKEKEAIESDRSDLEKAKS----QTFKQNKNIEIALA 7251
Query: 662 EVTELQEDLNKESKE------KQDLEKRVLEL 585
E+ + + L K SKE K + EK+ ++L
Sbjct: 7252 EIQQKRNALEKMSKEISRDRMKLEDEKKEIQL 7283
Score = 78.6 bits (192), Expect = 2e-11
Identities = 134/578 (23%), Positives = 246/578 (42%), Gaps = 76/578 (13%)
Frame = -3
Query: 2072 ESKVSVFEAAIATLNDELLNEKDD---KKCIVNDR-NILEAAKQALEYKVADLEAAKTTL 1905
+ K+ + EA + + ++ N +++ KKC + ++ E AK LE + D++ K
Sbjct: 10240 QEKLEISEADLKVMKEQCENAREETERKKCDIEEQIQNNENAKHLLEQERKDIDKQK--- 10296
Query: 1904 NDELERKKDD----------NNAIIKKALD--KRISDLKADAPQRDQEDDMNALIXXXXX 1761
EL+++ DD N + K++LD K++ + KA+ R ++D +
Sbjct: 10297 -QELQKQADDLDMRMIAHRENVEMSKRSLDEEKKLLEQKANEILRQRDD-----LEKEKE 10350
Query: 1760 XXXXXXXXXKIVSNLEVNILILHEELQKEKDDKTALI-KDLVAAEPGKRTVNEIVSHLES 1584
++ N N EE++ E D K I K+ E R +NE LE
Sbjct: 10351 DMMKKWNKLDVLQNEMQNENKAMEEIKYELDGKRNEINKEQQRLEESLRAINEEKGDLEI 10410
Query: 1583 KSRSLKEHFLREEEDEV--------LERSASNLAIMKAIREEELRKEKDGKSALVENGEG 1428
++ + EE V L++ S L K + E +K + ++ + +
Sbjct: 10411 MRADYEKQEQQIEEMRVEAKMERKELDQIKSELEKDKTEIDYEWKKLNNDRNMIEKERND 10470
Query: 1427 CEAEKQGL--EKTVLERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKT 1254
E K L ++ +E S LD I E K+K++K+ E E+Q +
Sbjct: 10471 LEKMKSELMTQRQQMEDERSELD--QKIKEANTEKDKIEKNKEIVERLMAEVEEQRNDFK 10528
Query: 1253 VLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEG--HEAEIERKL 1080
+ E + N ++ EK L + ++L+ K+ + + +E +E E ++
Sbjct: 10529 LKKEELALERQN---------IVDEKYLLAQCETELQNKSEQIRNMEEAVKNERETLKET 10579
Query: 1079 EASNLTHNDELHKEKDDKKSIMNDLDRVK-----------AEKQVLESKVSDLETTYSTL 933
EA L ++K + KSI+ + R K +KQ L++K LE +
Sbjct: 10580 EA-------HLQRDKKEIKSIIEETSRQKEDLEKISTGMNVQKQELKNKKDTLEQEREEI 10632
Query: 932 NN---ELQQKMDDNEAFLN---ERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNE 771
N+ + QQ++D+ +A + E D K E++ L+ E IEMKT + +++E
Sbjct: 10633 NHKWTQFQQRIDEFDAQVRKQKEEDLTNQKKMEEERKCLE-EVNGKIIEMKTKAELEHHE 10691
Query: 770 A-----EKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEV----TEL---------- 648
E QTL+++I + +E +T K K +D++ SE+ TE+
Sbjct: 10692 INQKIEELQTLQEQIMKEKEKAEAMTIKLKMEREDLDQIKSELVREKTEVDHEQKKLNDD 10751
Query: 647 -------QEDLNKESKE----KQDLEKRVLELTSKLEK 567
+EDL K E KQ++EK EL +K+++
Sbjct: 10752 IKMIEQEKEDLEKMKSEIMTQKQEMEKERSELDNKIQQ 10789
Score = 77.0 bits (188), Expect = 6e-11
Identities = 108/541 (19%), Positives = 221/541 (40%), Gaps = 58/541 (10%)
Frame = -3
Query: 2042 IATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAI 1863
IA + D+LL EK+D +E K+ + + +E ++ LND+ E +N +
Sbjct: 13675 IADMKDQLLKEKED----------VETTKERINREKEHIEKMQSQLNDQKEEMDLENQKL 13724
Query: 1862 I---------KKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEV 1710
+ AL+K + DL+ + +++NAL+ E
Sbjct: 13725 LYMKTEIQVKTNALEKMMQDLQKE------RENVNALVIQHQ-------------KEREQ 13765
Query: 1709 NILILHEELQKEKDDKTALIKDLVAAEPGK-------RTVNEIVSHLESKSRSLKEHFLR 1551
+++ E +KEK + + + E K ++++ S L+++S L E+ ++
Sbjct: 13766 RDILIEENKRKEKHAEAEIQRQFEDIESVKVRLVTESNQIDKMNSELKTRSEEL-ENLIK 13824
Query: 1550 EEEDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASN 1371
+++ E + KA+ E++ E + KS ++N + EK + + L++ +
Sbjct: 13825 KQQKEFETKENEMQRERKAL--EKMNAELERKSTELKN----KIEKVTVWEADLQKEKNK 13878
Query: 1370 LDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDR 1191
+ + I E E + +K+ + + E ++ + + +LE L D + L R
Sbjct: 13879 TEELKNILEREKSELYQEKAQVQQQKHEMETIRKTMKSEMENLECLRNELEDEKKSMLSR 13938
Query: 1190 VMAEKQALEKRCSDLEAKNAS----------LTDNQEGHEAEIERKLEASNLTHNDELHK 1041
+ EK ++K ++++++ S L D E +++ +E N+ + +
Sbjct: 13939 LSMEKHEIDKLKTEIQSEKESIEEEKKTLKQLKDENESKRTQLDNTIEKMNMDKLS-IQR 13997
Query: 1040 EKDDKKSIMNDLDRVKAEK-----------------------------QVLESKVSDLET 948
EKD + I DL R KAEK + L S +D+E
Sbjct: 13998 EKDSLEEIKADLQR-KAEKLDEEMRKAVQITSQISQDAKILDDDREKEEELRSMRADIER 14056
Query: 947 TYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEA 768
L +++Q L+ K+ LEK + + D+E K N+
Sbjct: 14057 QAKILESDVQL--------------LQTEKEILEKSKTENDLLREDLE----KQRKRNDL 14098
Query: 767 EKQTLKKRISELEEAISILT---DKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKR 597
Q L+K LE+ I+ +T D L ++++ E+ + +L+++ KE DL +
Sbjct: 14099 TLQELRKEKMALEQMITDITKEKDAVASLQNEVSLKQHELKNKETELDEQRKEMDDLRMQ 14158
Query: 596 V 594
+
Sbjct: 14159 L 14159
Score = 75.5 bits (184), Expect = 2e-10
Identities = 117/561 (20%), Positives = 241/561 (42%), Gaps = 56/561 (9%)
Frame = -3
Query: 2081 QALESKVSVFEAAIATLNDELLNEK----DDKKCIVNDRNILEAAKQALEYKVADLEAAK 1914
Q + ++ + IA D L+ K ++ + I N +++ ++ L+ A LE K
Sbjct: 10819 QLQKEELDIERQKIADEQDLLIQNKSELQNENERIRNINEVIKKERETLKEMEAHLEKEK 10878
Query: 1913 T---TLNDELERKKDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXX 1743
++ +E R+K+D L+K +D+K ++ D+ L
Sbjct: 10879 EEMKSITEETRRQKED--------LEKMSTDIKEQNQDLMKQRDL--LEQEKEDINHEWT 10928
Query: 1742 XXXKIVSNLEVNILILHEE---LQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRS 1572
+ + + + EE QKE ++ +++ A +T E+ + K +
Sbjct: 10929 QLQQRIDEFDAQVSKQKEEDLTKQKEMKEERKSLEETKARIIEMKTKAELEDIKKEKEKE 10988
Query: 1571 LKEHFLR---EEEDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLE 1401
+E +R E + + L+R S L ++ + E +K D K + E EKQ LE
Sbjct: 10989 EEEEEMRVKVEMDGKELDRIKSELKRERSEIDHEQKKLNDDKKII-------EQEKQNLE 11041
Query: 1400 KTVLERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPT---I 1230
K ++ + + EE E K E + E K+ +K ++++E I
Sbjct: 11042 KM----KSEIMKQRQQMEEERSELENKIKQTYIEKCD-IENSKEIVQKLMVEVEEQKHEI 11096
Query: 1229 PSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQE--GHEAEIERKLEASNLTHN 1056
+ L + ++ E+ L + S+L+ +N + + E E E +++EA
Sbjct: 11097 QFQKEELDIERQKIADEQDLLIQNKSELQNENERIRNLNEIIKKERETLKEMEA------ 11150
Query: 1055 DELHKEKDDKKSIMNDLDRVKAEKQVLESKVSD-----------LETTYSTLNN---ELQ 918
L K+K++ KS+ + R+K + + + + V+ LE +N+ +LQ
Sbjct: 11151 -HLEKKKEEIKSVSEETRRLKEDLEKMSTDVNKQNKDLMNQRDLLEQEREEINHKWKQLQ 11209
Query: 917 QKMDDNEAFLNERDGLEAVKQ-GLEKRVLDLEAT-IHDIEMKTGKDDDYNEAEKQTLKKR 744
Q++D+ +A ++++ + K+ G+++ LE T + IEMKT + + + EK+ +
Sbjct: 11210 QRIDEFDAQVSKQKEQDLPKEKGMKEDRKSLEETKANVIEMKTKAEPEEIKKEKEKENEE 11269
Query: 743 ISELEEAISILTDKAKKLL------------------KDINIWLSEVTELQEDLNKES-- 624
E EE I ++ + +K L K +N ++ + + +EDL K
Sbjct: 11270 EEEEEEEIRVIVETERKELYQIKSELERVRSEIDHEQKKLNDYMKMIEQEKEDLEKMKSE 11329
Query: 623 --KEKQDLEKRVLELTSKLEK 567
K++Q +E+ EL +K+++
Sbjct: 11330 IMKQRQQMEEERSELDNKIQQ 11350
Score = 75.1 bits (183), Expect = 2e-10
Identities = 111/513 (21%), Positives = 212/513 (41%), Gaps = 67/513 (13%)
Frame = -3
Query: 1904 NDELERKKDD-NNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKI 1728
ND +E+ ++D NNA+ K +D+ D++ QE A++ I
Sbjct: 1457 NDRVEQMREDVNNAL--KDIDQAKEDIQRQREVIAQEKVQPAIVATKSSEYAKTEEPGAI 1514
Query: 1727 VSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLRE 1548
S + L L +QKE+ + K+++ E K +N+I +++ +E ++
Sbjct: 1515 KS-YRASDLELSASIQKERQELEHY-KEIILKE--KHELNKIKEDVKAVKNDAEERMIKL 1570
Query: 1547 EEDEVLERSASNLAIMKAIREEELRKEKD--GKSALVENGEGCEAEKQGL---------E 1401
E+E E +++ R+ + KEK+ G A+ + KQ L E
Sbjct: 1571 HEEEK-EMKTKRVSLQNWERQLQTEKEKNQKGLDAIWNENQQLNERKQQLDIKELHLQSE 1629
Query: 1400 KTVLERR-------------------ASNLDTMDAIHEEELRKEKVDKSALTENGEGCEA 1278
K+ LE + AS D +I E + +++ ++ + C
Sbjct: 1630 KSKLEYKKPLEIKQVDAQVQTELMEDASEYDMALSIEELDKQRQFLEYFKQELLAQKCTM 1689
Query: 1277 EKQGPE-------------------KTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRC 1155
E+Q E +T D+E + L++ D + K ++K
Sbjct: 1690 ERQMAEIELSRDELSLREATLQTATQTTADMELQLELQKQELEQTKDEMERTKLEVQKGW 1749
Query: 1154 SDLEAKNASLTDNQEGHEAEIERKLEASNLTHND-ELHK---EKDDKKSIMNDLDRVKAE 987
DL+ + A + +E E+E+ + N D E K E D K ++ + + ++A+
Sbjct: 1750 VDLQTQIAESREKEEMVRIELEKARDVLNRIRQDVETEKQTMEADLKFTLAKEFENLEAQ 1809
Query: 986 KQVLESKVSDLETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDI 807
++++E + LE L E +ER +E + L++ +LE HD+
Sbjct: 1810 RKMMEDEKRALENMKYELQRESGYIERSKHNMHDERQNMENWAEKLKQEWEELEKKRHDM 1869
Query: 806 EM------KTGKD-DDYNEAEKQTLK--KRISELEEAISILTDKAKKLLKD----INIWL 666
+ + KD ++ E + TL K S++ E IS L + K +++ I I
Sbjct: 1870 QQLQTERSREIKDLENLRELNELTLNQIKTKSDVLEKISELNSQQKDEIENEKSKIKIRE 1929
Query: 665 SEVTELQEDLNKESKEKQDLEKRVLELTSKLEK 567
++ ++Q DLN++ KE QD++ V S+L+K
Sbjct: 1930 YDLQQMQTDLNRQQKEMQDIQNAVFMEKSELKK 1962
Score = 73.6 bits (179), Expect = 7e-10
Identities = 118/540 (21%), Positives = 235/540 (43%), Gaps = 37/540 (6%)
Frame = -3
Query: 2075 LESKVSVFEAAIATLN-DELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLND 1899
LE + FE A ++ E L E+ +K+ I D+ + ++ E + L K N+
Sbjct: 2743 LEKERDCFEKEKADISLREELEEQSEKEGI--DKTRVRIKQEMDELEQTRLNVVKELENN 2800
Query: 1898 ELERK--KDDNNAI--IKKALDKRISDLKADAPQRDQEDDMN---ALIXXXXXXXXXXXX 1740
EL+++ +D+ + I IK L K D + ++D E+D ++
Sbjct: 2801 ELQKQIIEDERDKIEQIKAELQKEAKD--TEKQRQDIENDRRNNEEMVIKLQNEKKDIET 2858
Query: 1739 XXKIVSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEH 1560
+ + E N+ +L + L+ ++D L K+ + + ++ LES++R +
Sbjct: 2859 STDRIRDEEANLRVLKQRLESDRD---TLEKERFDLKKTNTEMKDLEKQLESQNRQHEIQ 2915
Query: 1559 FLR-EEEDEVLERSASNLAIMKAIREEE---LRKEKDGKSALVENGEGCEAEKQGLEKTV 1392
++E E+LE+ L+ K E+E KEK S E E ++E++G+ KT
Sbjct: 2916 LAEIQKEREILEQLKLTLSKQKEDLEKERDCFEKEKADISLREELQE--QSEREGIGKT- 2972
Query: 1391 LERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDA 1212
R MD EL++ +++ EN E +KQ
Sbjct: 2973 ---RVRIKKEMD-----ELKQTRLNVVKELENNE---LQKQ------------------I 3003
Query: 1211 LQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASNLTHNDELHKEKD 1032
++ + D++ K L+K D E + + ++ +E E+ KL+ + +D
Sbjct: 3004 IEDERDKIEQIKAELQKEAEDTEKQRRDIEKDRRNNE-EMVIKLQNEKKDIETSTDRIRD 3062
Query: 1031 DKKSIMNDLDRVKAEKQVLESKVSDLETTYSTLNN---ELQQKMDDNEAFL----NERDG 873
++ ++ R+++++ LE + DLE T + + N +L+ ++ +E L ER+
Sbjct: 3063 EEANLEVQKQRLESDRDTLEKERFDLEKTKTEMGNLKKQLESQIRQHEIQLVEIQKEREI 3122
Query: 872 LEAVKQGLEKRVLDLEATIHDIEMKTG----KDDDYNEAEKQ-------TLKKRISELEE 726
LE +K L K+ DLE E + +D ++E++ +K+ + ELE+
Sbjct: 3123 LEQLKINLSKQKEDLEKERDCFEKEKADISLSEDLKEQSEREGIDNTRTRIKQEMDELEK 3182
Query: 725 AISIL------TDKAKKLLKDINIWLSEV-TELQEDLNKESKEKQDLEKRVLELTSKLEK 567
L + KK+++D + ++ EL+++ K E Q+ + + E +KL+K
Sbjct: 3183 TRQNLAKEQENNELQKKIIEDERDKIEQIKAELKKEAEKTKLELQNERQNLEEAGTKLKK 3242
Score = 73.2 bits (178), Expect = 9e-10
Identities = 128/570 (22%), Positives = 246/570 (43%), Gaps = 69/570 (12%)
Frame = -3
Query: 2072 ESKVSVFEAAIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDEL 1893
+ ++ + I L EL EK+ I+ DR+ L+ + ++L+ +T +ND +
Sbjct: 4167 QDELDQLKTEIQNLQQELEKEKE---IIMKDRS-------ELDLRQSELDKQQTNMNDII 4216
Query: 1892 ERKKDDNNAIIKKALDKRISDLKADAPQRDQE-DDMNALIXXXXXXXXXXXXXXKIVSNL 1716
E K++ +K LDK +++ + ++E D+M+ I +++
Sbjct: 4217 ETMKNE-----RKLLDKDKEEMEEQKQEMEKERDNMDQSIKSLDEDLKMMKLQKQVIEEE 4271
Query: 1715 EVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRS----LKEHFLRE 1548
+ + + ELQ+E D+ I+ + +R E ++ K R L E+ RE
Sbjct: 4272 KNKLEQMKFELQREADE----IRKIKEETQNERQSLEKMTKALIKEREDLVHLAEYTKRE 4327
Query: 1547 EE--DEVLERSASNLA-------IMKAIRE------EELRKEKDGKSALVENGEG---CE 1422
+E DE+ + S++A I++ +RE E++ EK+ KS L E+ E
Sbjct: 4328 KEMLDEMQVANKSSMADLQREKRILEEMRENISKQTEDIENEKE-KSKLREDELKKLQTE 4386
Query: 1421 AEKQ----GLEKTVLERRASNLDTMDAIHEEELRKEKVD-----KSALTENGEGCEAEKQ 1269
+KQ +EKT +E + + EL+K+ D K LTE E E +
Sbjct: 4387 VQKQQSEIDMEKTNIESERAVMIREKQNMMTELKKKSEDVEIQMKEILTEK-ELLENDSN 4445
Query: 1268 GPEKTVLDLEPTIPSL---NDALQRDLDRVMAEKQALEKRCSDLE--AKNASLTDNQEGH 1104
+K + DL+ + S+ +++L+ D + EK+ L++ +DL+ A + H
Sbjct: 4446 LLKKDMEDLKQKLMSIERDSESLKLDREAFGNEKEVLKQMKTDLQIQADEIEKIKLETQH 4505
Query: 1103 EAEIERKLEASNLTHNDELHK---EKDDKKSIMNDLDR--------VKAEKQVLESKVSD 957
+ + + A DE++ E + K ++N++DR ++++K +LE + +
Sbjct: 4506 DRQRVEEKTAQIQKDRDEINNLIVETNRKDMVLNEMDRDIEEKIKSIQSDKDMLEKERHN 4565
Query: 956 LETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDY 777
LE T S L + E ER +E +K+ + + + +++ H E K D+
Sbjct: 4566 LEKTRSELARAKENLETQREI---ERKDIEKMKKNISREMHEIK---HQEEQMKQKQDEL 4619
Query: 776 N-------------EAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLS--------E 660
+ E EK+ + K S+L+ S L DK + + DI + +
Sbjct: 4620 DQLKTEIQNLQQELEKEKEIIMKARSQLDLRQSEL-DKQQTNMNDIMETMKNERKQLDKD 4678
Query: 659 VTELQEDLNKESKEKQDLEKRVLELTSKLE 570
E +E + KEK D ++ L L+
Sbjct: 4679 KEETEEQKQEMEKEKHDFDQSRKSLDEDLK 4708
Score = 73.2 bits (178), Expect = 9e-10
Identities = 101/486 (20%), Positives = 210/486 (43%), Gaps = 13/486 (2%)
Frame = -3
Query: 2036 TLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIK 1857
TL + N + I N+ L + + L D+ L + E + N +++
Sbjct: 7504 TLEEMRANISKQVETITNENKSLSSRESELAKLQEDI------LQQQQEMDELKNTIMME 7557
Query: 1856 KA-LDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQ 1680
LD+R SD+ D Q++ +D M+ ++N+E L + + +
Sbjct: 7558 MCQLDQRQSDI--DLLQKEVDDLMD--------------FTKTEMANVERERLEVLAQTR 7601
Query: 1679 KEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEV-LERSASNLAI 1503
K D +L + A E + +NE +E + L ++ ++D++ ++R NL +
Sbjct: 7602 NIKSDMVSLKMEKEACEQLRLKLNEEKDLIEKERELLTKNLDHTDKDKMDMKRELENLKV 7661
Query: 1502 MKAIREEELRKEKDGKSALVENGEGCE--AEKQGLEKTVLERRASN----LDTMDAIHEE 1341
K + E ++ + K +L G + +EK E+ ++E A+ LD + E
Sbjct: 7662 EKETIKNEKKELEKMKISLQRKAIGFKEFSEKTKDERPIVEEMAAQFTRQLDISERPAEG 7721
Query: 1340 ELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEK 1161
+ +E++D++ + EKT DL+ T +N D + + ++ L K
Sbjct: 7722 KFIEERLDQTEKKRRKTYYTEDLFQEEKT--DLQKTKEEIN----YDREEIYRQRTELNK 7775
Query: 1160 RCSDLEAKNASLTDNQEGHEAEIERKLEASNLTHNDELHKEKDDKKSIMNDLDRVKAEKQ 981
E E +++ SNL + + KEK+ + N+LD+++AE
Sbjct: 7776 -------------------EKETLKQMHTSNLKEIENIEKEKEKIQRTWNELDQIRAE-- 7814
Query: 980 VLESKVSDLETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEM 801
L++K D++ T + + E + D E NE+D L+ ++ ++K + +L+ E
Sbjct: 7815 -LQNKQRDMDDTTNIMMKEKAELARDLENLQNEKDELQKSRENIQKLMKELQ------EE 7867
Query: 800 KTGKDDDYNEAEKQ---TLKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQ--EDL 636
+ + N+ +Q +K + L+E + + + + L+ D I ++ +LQ +D+
Sbjct: 7868 RLKTSEALNKERQQFTEEIKLKNDSLDEIQAEIDRQKRALVTDKEIITKQMMDLQKTQDV 7927
Query: 635 NKESKE 618
++S E
Sbjct: 7928 RRQSDE 7933
Score = 72.8 bits (177), Expect = 1e-09
Identities = 109/496 (21%), Positives = 222/496 (44%), Gaps = 26/496 (5%)
Frame = -3
Query: 1994 CIVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAI-IKKALDKRISDLKAD 1818
C+ D L+ ++A E + L+ KT ELER+ D+ I ++ D++ + A
Sbjct: 5544 CLDRDAESLKLDREAFENEKEVLKQMKT----ELEREADEIEKIKLETQHDRQRVEEMAA 5599
Query: 1817 APQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDKTALIKDLV 1638
Q+D+ D++N LI L + E+++ + DK L K+
Sbjct: 5600 QIQKDR-DEINNLIEETNRKDMV----------LNEKNRDIEEKIKSIQSDKDMLEKEKH 5648
Query: 1637 AAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNLAI-MKAIR--EEELRKE 1467
E + + ++ LE + + +E ED LE+ N+ M I+ EE++ ++
Sbjct: 5649 DLEKTRSELYKVKEDLEKQKENTLAEIQKERED--LEKMNENITREMHEIKHQEEQMNQK 5706
Query: 1466 KDG----KSALVENGEGCEAEKQGL--EKTVLERRASNLDTMDAIHEEELRKEKVDKSAL 1305
+D K+ + + E EK+ + +++ L+ R S LD + + K ++ L
Sbjct: 5707 QDELDQLKTEIQNLQQELEKEKEIIMKDRSQLDLRQSELDKQQTNMNDIMETMKNERKQL 5766
Query: 1304 TENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASL 1125
++ E E +KQ EK +++ + SL++ D ++ +KQ E+ + LE L
Sbjct: 5767 DKDKEEMEEQKQEMEKERDNMDQSRKSLDE----DQKKMKLQKQMFEEEKNKLEQMKIEL 5822
Query: 1124 TDNQEGHEAEIERKLEASNLTHNDELHKEKDD----KKSIMNDLDRVKAEKQVL------ 975
EA+ K++ L K ++ K+S+ + + K EK++L
Sbjct: 5823 E-----READEISKIKEETQNKRQRLEKMTEELIREKESLAHLAEDTKTEKKILDEMKVA 5877
Query: 974 -ESKVSDLETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMK 798
ES ++DL+ S L ++M +N + L E E K L E + ++ +
Sbjct: 5878 NESSMADLQREKSIL-----EEMRENISKLKEYIDNEKEKSKLR------EDELKKLQTE 5926
Query: 797 TGKDDDYNEAEKQTLK-KRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESK 621
K + EK ++ +R + + E +++T+ KK +D+ I + E+ +E L+ + K
Sbjct: 5927 VQKQQSKIDMEKTNIESERAAMIREKQNMMTE-LKKKSEDVEIQMKEILTEKELLHNDRK 5985
Query: 620 ----EKQDLEKRVLEL 585
+ ++L++++++L
Sbjct: 5986 LLTRDVENLQQKLIDL 6001
Score = 72.4 bits (176), Expect = 2e-09
Identities = 119/603 (19%), Positives = 247/603 (40%), Gaps = 64/603 (10%)
Frame = -3
Query: 2042 IATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAI 1863
+ L E+ ++ K ++++ I ++ Q L + + L E+E K D
Sbjct: 9072 VRNLKGEMERRMEESKVEIDEKEIFKSEIQRLIQDIGQIRENLGGLKTEIENTKRD---- 9127
Query: 1862 IKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEEL 1683
K L+K ++L + Q+++E L + ++E++ ++ E+
Sbjct: 9128 -KSNLEKMKAEL--EEKQQEEESMREILQKEKEELEQLKKDINREKEDIEISRELVESEI 9184
Query: 1682 -----------QKEKDDKTALIKDLVAAEPGKRTVNEIVSHLES----------KSRSLK 1566
QK K++ + ++L+ + +N V HL K ++
Sbjct: 9185 YEGEVKGFTDVQKYKEELQIVTEELLTKKRNLEQLNSDVQHLMQTLEEVDIQYIKKKAEL 9244
Query: 1565 EHFLRE--EEDEVLERSASNL--------------AIMKAIREEELRKEKDGKSALVENG 1434
EH E + +++LE+ L +++I E L+K +D + +
Sbjct: 9245 EHITSEIQKREQILEKQKKKLEENGWIIEEIEMMKVTLESINMEILQKRED----MEKEK 9300
Query: 1433 EGCEAEKQGLE--KTVLERRASNLDT--MDAIHEEELRKEKVDKSALTENGEGCEAEKQG 1266
E EKQ E + L+R+ +++ I E++ K K+D E E E +
Sbjct: 9301 ENLRREKQETELFRGELQRQRDEVESSRQALIMEKDQFKLKIDHQR-NEMSAAFEKEHKR 9359
Query: 1265 PEKTVLDLE----PTIPSLNDA------LQRDLDRVMAEKQALEKRCSDLEAKNASLTDN 1116
E DLE SLNDA LQ+ + + EK+ +E+ ++ + +
Sbjct: 9360 LENMENDLENQRAKLAESLNDAAKMEQKLQQMKNELNKEKEQVEEMKQMVKTERVKIEQE 9419
Query: 1115 QE-----------GHEAEIERKLEASNLTHNDELHKEKDDKKSIMNDLD-RVKAEKQVLE 972
+E GHE ++++K E + D+L ++ + + + DL +++ ++Q +E
Sbjct: 9420 KEEMRKQTQEIEDGHE-KLQKKTEIA-----DKLLQDANSESDRLKDLSMKLQMQRQDIE 9473
Query: 971 SKVSDLETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTG 792
+++ET +L+ ++ DD N+RD E LE + +L D+E K
Sbjct: 9474 KTNTEMETKKRSLDRMSRELQDDKIRLKNDRDAYEKDMTHLELKREELVRETEDLERKIL 9533
Query: 791 KDDDYNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQ 612
+ + +E K+ ++ + LE + K + K++ SE +L ++
Sbjct: 9534 QQREQDEMAKRDIENQTEALEVMKVDILKKRNEFAKEMENVHSERQKLLLLQGALQSQES 9593
Query: 611 DLEKRV-LELTSKLEKCICGARDGLSTIKEAWMSDCMVPDNWVPFEDLVQGFSRKTSPLD 435
+LE RV +E L++ + + E MS+ + + + L++ R+ L+
Sbjct: 9594 ELENRVFMEEQKHLKQAKAETEECRKQLAE--MSETVTTEQ-NEYRKLIEELQREKEQLE 9650
Query: 434 ITK 426
I+K
Sbjct: 9651 ISK 9653
Score = 71.6 bits (174), Expect = 3e-09
Identities = 103/494 (20%), Positives = 209/494 (42%), Gaps = 8/494 (1%)
Frame = -3
Query: 2042 IATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLND---ELERKKDDN 1872
I ++ +E +K+D + I N+ KQ L+ K LE + +N + +++ D+
Sbjct: 10590 IKSIIEETSRQKEDLEKISTGMNV---QKQELKNKKDTLEQEREEINHKWTQFQQRIDEF 10646
Query: 1871 NAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILH 1692
+A ++K ++ +++ K +R +++N I ++ + H
Sbjct: 10647 DAQVRKQKEEDLTNQKKMEEERKCLEEVNGKII-----------------EMKTKAELEH 10689
Query: 1691 EELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASN 1512
E+ ++ I++L +T+ E + + K+ ++ E ED L++ S
Sbjct: 10690 HEINQK-------IEEL-------QTLQEQIMKEKEKAEAMTIKLKMERED--LDQIKSE 10733
Query: 1511 LAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGL--EKTVLERRASNLDTMDAIHEEE 1338
L K + E +K D + + E E K + +K +E+ S LD + I + +
Sbjct: 10734 LVREKTEVDHEQKKLNDDIKMIEQEKEDLEKMKSEIMTQKQEMEKERSELD--NKIQQTD 10791
Query: 1337 LRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKR 1158
L K ++KS E E+Q E I + L + ++ E+ L +
Sbjct: 10792 LEKHDIEKSKEIVEKLMFEVEEQRHE---------IQLQKEELDIERQKIADEQDLLIQN 10842
Query: 1157 CSDLEAKNASLTDNQE--GHEAEIERKLEASNLTHNDELHKEKDDKKSIMNDLDRVKAEK 984
S+L+ +N + + E E E +++EA L KEK++ KSI + R +K
Sbjct: 10843 KSELQNENERIRNINEVIKKERETLKEMEA-------HLEKEKEEMKSITEETRR---QK 10892
Query: 983 QVLESKVSDLETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIE 804
+ LE +D++ + N+ + +RD LE K+ + L+ I + +
Sbjct: 10893 EDLEKMSTDIK--------------EQNQDLMKQRDLLEQEKEDINHEWTQLQQRIDEFD 10938
Query: 803 MKTGKDDDYNEAEKQTLKKRISELEEA-ISILTDKAKKLLKDINIWLSEVTELQEDLNKE 627
+ K + + +++ +K+ LEE I+ K K L+DI + E +E K
Sbjct: 10939 AQVSKQKEEDLTKQKEMKEERKSLEETKARIIEMKTKAELEDIKKEKEKEEEEEEMRVKV 10998
Query: 626 SKEKQDLEKRVLEL 585
+ ++L++ EL
Sbjct: 10999 EMDGKELDRIKSEL 11012
Score = 71.6 bits (174), Expect = 3e-09
Identities = 112/532 (21%), Positives = 220/532 (41%), Gaps = 62/532 (11%)
Frame = -3
Query: 1982 DRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKAL--------DKRISDL 1827
D+ ++ K +LE ADL+ L++E+ + + I + A ++ + +
Sbjct: 13991 DKLSIQREKDSLEEIKADLQRKAEKLDEEMRKAVQITSQISQDAKILDDDREKEEELRSM 14050
Query: 1826 KADAPQRDQ--EDDMNALIXXXXXXXXXXXXXXKIVSNLEV----NILILHEELQKEKDD 1665
+AD ++ + E D+ L + +LE N L L +EL+KEK
Sbjct: 14051 RADIERQAKILESDVQLLQTEKEILEKSKTENDLLREDLEKQRKRNDLTL-QELRKEKMA 14109
Query: 1664 KTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVLE--RSASNLAIMKAI 1491
+I D+ + + V+ L+++ SLK+H L+ +E E+ E + +L + +
Sbjct: 14110 LEQMITDITKEK-------DAVASLQNEV-SLKQHELKNKETELDEQRKEMDDLRMQLEM 14161
Query: 1490 REEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTM---------------D 1356
R+ K++ + + + ++ + E R D + D
Sbjct: 14162 RQNSTNKQQQEVDVFIVENMKMRNDLESMKTLLDEERRQLQDNIKTFEDQKNVLHPSKTD 14221
Query: 1355 AIHE-EELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLN---DALQRDLDRV 1188
A+ + +EL K D E+ E E K ++ + + SLN + ++++
Sbjct: 14222 AVQQTDELEKFTTDIKTEKEHVEKEREEIDVLNKEIIKSKEELQSLNLEIEMFKQEIAGK 14281
Query: 1187 MAEKQALEKRCSDLEA------------KNASLTDNQEGHEAEIERKL-----EASNLTH 1059
A+ ++LE+ +DL A K ++ D ++ E E++ L E L +
Sbjct: 14282 RAQIESLEQLRADLLAGADDIKTLVQTEKQMAIEDTEKKTEVELQMNLQKQKNELEELRN 14341
Query: 1058 NDELHKEKDDKKSIMNDLDR---------VKAEKQVLESKVSDLETTYSTLNNELQQKMD 906
E K + + + IM D + +K+E+ VLE + S+L LN ++Q++ +
Sbjct: 14342 TIEAEKHQVENRKIMLDKQQKEVEDIMTVIKSERDVLEKEKSELNKLSHVLNEKVQREQE 14401
Query: 905 DNEAFLN-ERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELE 729
+ E L ERD +E K+ +E +EKQ++++ +EL
Sbjct: 14402 ELERLLEKERDDIENCKKIIE-------------------------SEKQSIERERAEL- 14435
Query: 728 EAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLELTSKL 573
K+L +++ + E T LQ+D N KEK+ LE T ++
Sbjct: 14436 ----------KRLKEEVEVQ-HERTLLQQDKNMIQKEKEHLEGEKARTTEEI 14476
Score = 70.1 bits (170), Expect = 7e-09
Identities = 113/520 (21%), Positives = 220/520 (42%), Gaps = 45/520 (8%)
Frame = -3
Query: 2018 LNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKA---L 1848
L EK+ + + D L ++ L+ A + K + E +KD+ AI++K +
Sbjct: 13167 LQEKNVQMGTILDE--LNKRQEELDAIKAKTQREKEQMGHTEELEKDELIAILQKREEIV 13224
Query: 1847 DKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILI-LHEELQKEK 1671
+ + +++ + +E D + +++ N E + L + L+K+K
Sbjct: 13225 KRHMEEIQNQREELQKEKDQFGNMQAELQKGQLEMEMHQLMLNSERDELNGMRVNLEKQK 13284
Query: 1670 DDKTALIKDLVAAEPG---------KRTVNEIVSHLESKSRSLK----EHFLREEEDEVL 1530
++ + ++L + P K+ V E+ + L + + E R E+ + +
Sbjct: 13285 EEFELMQQNLESRRPESLLEDILKEKKRVEEMAAQLSKEQEEFRNIMSETIKRMEKIKQI 13344
Query: 1529 ERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAI 1350
E I A EE +KE D + + E CE ++ + + L + + +D
Sbjct: 13345 EGEIKTKQIEMACLEELKQKELDEQKNMRE----CENQELQMRREELAKMKTEID----- 13395
Query: 1349 HEEELRKEKVDKSALTENGEGCEAE-------KQGPEKTVLDLEPTIPSLNDALQRDLDR 1191
+ ++++ K E CE E K+ PEK +++ +D + +D
Sbjct: 13396 ----IERDEIQKLRKQYEKEKCELEQIKPDLQKREPEKIDAEVQ------HDEIHGGIDS 13445
Query: 1190 VMAEKQALEKRCSDLEAKNASLT----------DNQEGHEAEIERKLEASNLTHNDELHK 1041
+ E++ +EK +DL+ K D E EAEIE+ A ND
Sbjct: 13446 LKEEREEIEKMKADLQNKLREAENMRDIMKREKDELEKKEAEIEQM--AVETEDNDSDKN 13503
Query: 1040 EKDDKKSIMNDLDRVKAEKQVLES-------KVSDLETTYSTLNNE---LQQKMDDNEAF 891
+D+ I L K +K LE + ++LET L E L +K+ + E F
Sbjct: 13504 LQDEMMKIEAILKVTKKQKNYLEQMNENLTREKTELETNCQMLEREKTELNKKVKETEEF 13563
Query: 890 -LNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISI 714
+++ + EA ++ +E RV+D A H+ ++K +++ N E+ +KK+ LEE+++
Sbjct: 13564 HMSKMEEREAERKTIE-RVMDEMAEEHE-KIKKEREELVNMEEE--IKKQRRVLEESMNE 13619
Query: 713 LTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRV 594
+T K +ELQ + ++ K+KQ LE +
Sbjct: 13620 MTKKK--------------SELQHERSELYKQKQQLEDMI 13645
Score = 68.9 bits (167), Expect = 2e-08
Identities = 118/565 (20%), Positives = 246/565 (43%), Gaps = 87/565 (15%)
Frame = -3
Query: 2000 KKC-IVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKALD-----KR 1839
+KC I N + I++ +E + +++ K L+ E ++ D+ + +I+ + +R
Sbjct: 11071 EKCDIENSKEIVQKLMVEVEEQKHEIQFQKEELDIERQKIADEQDLLIQNKSELQNENER 11130
Query: 1838 ISDL-KADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDK 1662
I +L + +R+ +M A + + ++ L E+L+K D
Sbjct: 11131 IRNLNEIIKKERETLKEMEAHLEKKKEE----------IKSVSEETRRLKEDLEKMSTDV 11180
Query: 1661 TALIKDLVAAEPGKRTVNEIVSHL----------------ESKSRSLKEHFLREEEDEVL 1530
KDL+ E ++H + K + L + +E+ + L
Sbjct: 11181 NKQNKDLMNQRDLLEQEREEINHKWKQLQQRIDEFDAQVSKQKEQDLPKEKGMKEDRKSL 11240
Query: 1529 ERSASNLAIMKAIRE-EELRKEKDGKSALVENGEG-----CEAEKQGLE--KTVLERRAS 1374
E + +N+ MK E EE++KEK+ ++ E E E E++ L K+ LER S
Sbjct: 11241 EETKANVIEMKTKAEPEEIKKEKEKENEEEEEEEEEIRVIVETERKELYQIKSELERVRS 11300
Query: 1373 NLDT--------MDAIHEEELRKEKV-------------DKSALTENGEGCEAEKQGPEK 1257
+D M I +E+ EK+ ++S L + EK EK
Sbjct: 11301 EIDHEQKKLNDYMKMIEQEKEDLEKMKSEIMKQRQQMEEERSELDNKIQQTNLEKHDIEK 11360
Query: 1256 TVLDLEPTIPSLNDA---LQRDLDRVMAEKQALEKRCSDLEAKNASL-TDNQEGHEAEIE 1089
+ +E + + + +Q + + E+Q + + L A L +N+ + + E
Sbjct: 11361 SKEIVEKLMVEVEEQRKDIQLQKEELDIERQKIADEQNLLVQNKAKLQNENERIKKVDEE 11420
Query: 1088 RKLEASNLTHND-ELHKEKDDKKSIMNDLDRVKAEKQVLESKVSD-----------LETT 945
K E L + L KEK++ +SI+ + R K + + + + +++ LE
Sbjct: 11421 IKKERETLREMEIHLKKEKEELRSIIEETQRRKEDLEKMSTDINEQKLHLKNQRDLLEQE 11480
Query: 944 YSTLNNE---LQQKMDDNEAFLNE------RDGLEAVKQGLEK---RVLDLE--ATIHDI 807
+N+E LQQ++D+ +A +++ + +E ++ LE+ R+++++ A + +I
Sbjct: 11481 REEINHEMTQLQQRIDEFDAQVSKQREDLTKQEMEEERKSLEETKARIIEMKTKAELQEI 11540
Query: 806 EMKTGKDDDYN-----EAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQE 642
+ ++D+ E E++ L + SEL+ S + + KKL D I E +L++
Sbjct: 11541 MQEKEEEDEEEMRVIVEMEREELNQIKSELKRVRSEIDHEQKKLNDDKKIIEQEKEDLEK 11600
Query: 641 DLNKESKEKQDLEKRVLELTSKLEK 567
++ ++Q +E+ EL +K+++
Sbjct: 11601 MKSEIMTQRQQMEEERSELDNKIKQ 11625
Score = 68.2 bits (165), Expect = 3e-08
Identities = 116/566 (20%), Positives = 230/566 (40%), Gaps = 63/566 (11%)
Frame = -3
Query: 2075 LESKVSVFEAAIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDE 1896
+E ++ + +A L + E D++K N+ E Q L+ + +L KT + +
Sbjct: 13344 IEGEIKTKQIEMACLEELKQKELDEQK------NMRECENQELQMRREELAKMKTEI--D 13395
Query: 1895 LERKKDDNNAIIKKALDKRISDLKADAP--QRDQEDDMNALIXXXXXXXXXXXXXXKIVS 1722
+ER D ++K +K +L+ P Q+ + + ++A +
Sbjct: 13396 IER---DEIQKLRKQYEKEKCELEQIKPDLQKREPEKIDAEVQH---------------D 13437
Query: 1721 NLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEE 1542
+ I L EE ++ + K L L AE + + LE K +++ + E+
Sbjct: 13438 EIHGGIDSLKEEREEIEKMKADLQNKLREAENMRDIMKREKDELEKKEAEIEQMAVETED 13497
Query: 1541 DEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKT--VLERRASNL 1368
++ + + ++AI L+ K K+ L + E EK LE +LER + L
Sbjct: 13498 NDSDKNLQDEMMKIEAI----LKVTKKQKNYLEQMNENLTREKTELETNCQMLEREKTEL 13553
Query: 1367 DT---------MDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLND 1215
+ M + E E ++ +++ + E E E K+ E+ V ++E I
Sbjct: 13554 NKKVKETEEFHMSKMEEREAERKTIER-VMDEMAEEHEKIKKEREELV-NMEEEIKKQRR 13611
Query: 1214 ALQRDLDRVMAEKQALEKRCSDLEAKNASLTD---------------NQEGHEAEIERKL 1080
L+ ++ + +K L+ S+L + L D Q+ + +I ++
Sbjct: 13612 VLEESMNEMTKKKSELQHERSELYKQKQQLEDMIASESKRDVDTERSRQDKEDEQILKRE 13671
Query: 1079 EASNLTHNDELHKEKDDKKSIMNDLDRVKAEKQVLESKVSD--------------LETTY 942
D+L KEK+D ++ ++R K + ++S+++D ++T
Sbjct: 13672 REEIADMKDQLLKEKEDVETTKERINREKEHIEKMQSQLNDQKEEMDLENQKLLYMKTEI 13731
Query: 941 STLNNELQQKMDDNEAFLNERDGLEAV-----KQGLEKRVL-------------DLEATI 816
N L++ M D + ER+ + A+ K+ ++ +L +++
Sbjct: 13732 QVKTNALEKMMQDLQ---KERENVNALVIQHQKEREQRDILIEENKRKEKHAEAEIQRQF 13788
Query: 815 HDIE-MKTGKDDDYNEAEKQT--LKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQ 645
DIE +K + N+ +K LK R ELE I KK K+ ++ E+Q
Sbjct: 13789 EDIESVKVRLVTESNQIDKMNSELKTRSEELENLI-------KKQQKEFE---TKENEMQ 13838
Query: 644 EDLNKESKEKQDLEKRVLELTSKLEK 567
+ K +LE++ EL +K+EK
Sbjct: 13839 RERKALEKMNAELERKSTELKNKIEK 13864
Score = 67.8 bits (164), Expect = 4e-08
Identities = 122/593 (20%), Positives = 248/593 (41%), Gaps = 81/593 (13%)
Frame = -3
Query: 2027 DELLNEKD-DKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIK-- 1857
D + + D ++ I N + I++ +E + D+ K L+ E ++ D+ +++
Sbjct: 11620 DNKIKQTDLERHDIENSKEIVQKLMVKVEEQRKDIRLQKEELDIERQKIADEQGLVVQNK 11679
Query: 1856 ----------KALDKRISDLKA-----DAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVS 1722
K +D+ I K +A R ++++M ++I
Sbjct: 11680 AKLQNENERIKEMDEEIKKEKETLKEMEAHLRKEKEEMRSVIEETQRRKKEDLEKMSTDV 11739
Query: 1721 NLEVNILILHEELQKEKDDK-----TALIKDLVAAEPGKRTVNEIVSHL-ESKSRSLKEH 1560
N + L+ +L K++ ++ T L ++ ++E + + + K L +
Sbjct: 11740 NKQNQDLMNQRDLLKQEREEINHKWTQL----------QQRIDEFDAQVSKQKEEDLTKQ 11789
Query: 1559 FLREEEDEVLERSASNLAIMKAIRE-EELRKEKDGKSALVENGEGCEAEKQGLE--KTVL 1389
EEE + LE + + MK E E+++KEK+ + V + E +K+ L+ K+ L
Sbjct: 11790 KKMEEERKSLEETKIKIIEMKTKTEPEKIKKEKEKEEEEVMRAK-VEMKKEELDQIKSQL 11848
Query: 1388 ERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDAL 1209
ER S +D HE+ +K DK + + E E K K +E L++ +
Sbjct: 11849 ERVRSEID-----HEQ--KKLNDDKKMIEQEKEDLEKMKSEIMKQRQQMEEERSELDNKI 11901
Query: 1208 -QRDLDR--VMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIER---------------K 1083
Q DL+R + K+ ++K ++E + + +E E +IER K
Sbjct: 11902 KQTDLERHDIENSKEIVQKLMVEVEEQRKDIRLQKE--ELDIERQKIADEQGLVVQNKAK 11959
Query: 1082 LEASN---LTHNDELHKEKDDKKSIMNDLDRVKAE-KQVLES----KVSDLETTYSTLNN 927
L+ N ++E+ KEK+ K + L + K E + V+E + DLE + +N
Sbjct: 11960 LQNENERIKEMDEEIKKEKETLKEMEAHLRKEKEEMRSVIEETQRRQKEDLEKMSTDVNK 12019
Query: 926 ELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATI-----HDIEMKTGKDDDYNEAEK 762
+ Q M+ + ER+ + L++R+ + +A + D+ + +++ E+
Sbjct: 12020 QNQDLMNQRDLLKQEREEINHKWTQLQQRIDEFDAQVSKQKEEDLTKQKKMEEERKSLEE 12079
Query: 761 QTL---------------KKRISELEEAISILTDKAKKLLKDINIWL----SEVTELQED 639
+ K++ E EE + + K+ L I L SE+ Q+
Sbjct: 12080 TKIKIIEMKTKTEPEKIKKEKEKEEEEVMRAKVEMKKEELDQIKSQLERVRSEIDHEQKK 12139
Query: 638 LNKESK----EKQDLEKRVLELTSKLEKCICGARDGLSTIKEAWMSDCMVPDN 492
LN + K EK+DLEK E+ + ++ + + I++ ++ C + ++
Sbjct: 12140 LNDDKKMIEQEKEDLEKMKSEIMKQRQQMEEERSELENKIRQTYIEKCDIENS 12192
Score = 67.4 bits (163), Expect = 5e-08
Identities = 92/447 (20%), Positives = 194/447 (43%), Gaps = 36/447 (8%)
Frame = -3
Query: 1622 KRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNLAIMKAIREEELRKEKDG-KSAL 1446
+ T E++ LE + R+ K R L + +++K KD K
Sbjct: 80 RMTEPELIQELEWRQRNTKHTQTETGSPPSSPREKRRLEDKSGL-SSDIQKRKDSLKRRR 138
Query: 1445 VENGEGCEAEKQGLEKTVLERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQG 1266
E E ++ E T ER + +D M ++++++++ + + +T EK
Sbjct: 139 FETMRAIEQIEKLWEGTKQER--TEIDNM----KQKIQRQQDEITRMT-------TEKGQ 185
Query: 1265 PEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIER 1086
E+T+ ++ I + + + R+ + V E++ +E+ SDL+A+ +SL Q+ E ER
Sbjct: 186 LERTITHMKAEIDHIRERMDRNKEEVNRERERVEQMRSDLQAEQSSL--QQKRDEIMTER 243
Query: 1085 K----LEASNLTHNDELHKEKDDKKSIMNDLDRVKAEKQV----LESKVSDLETTYSTL- 933
+ + L +EL ++ K M ++++K+ QV +E K+ + + +
Sbjct: 244 QNLEMIRYETLRQQEELESNRESTKHEMERMEQMKSAIQVQINEIEMKIGETQKAKDLME 303
Query: 932 ---------NNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDD 780
NEL++K +D +RD E +K L++ +++E H+ E + +
Sbjct: 304 QMKAEIEDEKNELEKKKED---IKRQRDQFEQIKLDLQQVKMEMEQRWHETEKEGLEQRA 360
Query: 779 YNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEV--TELQEDLNKESK----- 621
+ EK+ LK E++ + ++ ++ K + +S++ L+E+ E+K
Sbjct: 361 VIQREKEQLKYLQDEIQR-VREEVERNREFSKQEHARISQLRAQALEENNLIENKWHDIL 419
Query: 620 -EKQDLEKRVLELTSKLEKCICGARDGLSTIKEAW----MSDCMVPDNWVPFEDLVQGFS 456
+++DLE+ E+ E+ + +K+ W + + + + E V
Sbjct: 420 RKEKDLEEMKHEIERGREELVMNG----ELVKKEWEKIEQAKVDIQSHMISMEGRVDEIK 475
Query: 455 RKTSPLDITKT-----CDAVDISEDST 390
R+T L KT DA++ +D T
Sbjct: 476 RETERLKHIKTEMQRDKDALEKQKDDT 502
Score = 65.1 bits (157), Expect = 2e-07
Identities = 117/597 (19%), Positives = 242/597 (40%), Gaps = 108/597 (18%)
Frame = -3
Query: 2033 LNDELLNEKDDKKCIVN--------DRNILEAAKQALEYKVADLEAAKTTLNDELERKKD 1878
LN+ LN+ K ++ ++ +E K ++ + DL+ +T LN + + +D
Sbjct: 1889 LNELTLNQIKTKSDVLEKISELNSQQKDEIENEKSKIKIREYDLQQMQTDLNRQQKEMQD 1948
Query: 1877 DNNAII--KKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLE-VN 1707
NA+ K L K ++ A Q Q DM NL+
Sbjct: 1949 IQNAVFMEKSELKKSQDEI---AEQLKQVGDMMQFTQNEK-------------DNLDRER 1992
Query: 1706 ILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEV-L 1530
I+ ++LQ E+D L ++L + + K+ V LE SL E+ ++ L
Sbjct: 1993 AAIIEQKLQMERDMTHLLNRELESLKLVKKEVLNEKRLLEDCRISLMRDMQDLEQMKINL 2052
Query: 1529 ERSASNLAIMKAIREEELRKEKDGKSALVENGEGCE----AEKQGLEKTVLERRASNLDT 1362
ER + + + EE K + L E+ E AEKQ LE +E + +
Sbjct: 2053 EREKEEMQLQRQSIAEEKDKLESVLQTLAEDTEKLRIDTLAEKQKLEDAAVELQKERDEI 2112
Query: 1361 MDAIHEEELRKEKVDK----------------------SALTENGEGC------------ 1284
M+ E + ++E VDK +A+ EN
Sbjct: 2113 MNIAEETKRKREDVDKIRVGIEKQEITFKDLKADLQKEAAIVENQRQAVQKDIQNVKDME 2172
Query: 1283 ---EAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQ 1113
+ E+Q ++ V ++E +L D +Q ++D+ E+Q +E + +LE + + L +++
Sbjct: 2173 VQIQKERQYMDRLVEEIEKRTKAL-DEMQMEVDK---ERQEVESKRDELEQETSKLREDE 2228
Query: 1112 EGH----------EAEIERK-----LEASNLT----------------HNDELHKEK--D 1032
+ +AEI+++ L++ N++ N+ +K+K D
Sbjct: 2229 DEFSRQKEKNNIIQAEIQKESDNLELQSENISKERTIFELEKEHLGLRENEAEYKQKQID 2288
Query: 1031 DKKSIMN----DLDRVKAEKQVLESKVSDLETTYSTLNNELQQKMDDNEAFLNERDGLEA 864
+ ++ + +++++A+K K ++T L+++ + E+ E + +E
Sbjct: 2289 ELQNKLRMEKVQVEQMQADKDQQRKKAEYVKTARGRETTALEEQRQEMESLREEYENVEK 2348
Query: 863 VKQGLEKRVLDLEATIHDIEMKTGKDDDYNEA----------EKQTLKKRISELEEAISI 714
K+ + ++ E+ + +EM+ Y E ++Q +K I ++ + I
Sbjct: 2349 QKKHVNEQKELFESRMKSLEMENEAMKKYKEKLDKEYEDLQFQRQLFEKEIQQMRTELQI 2408
Query: 713 LTDKAKKLLKDINIWLSEV------TELQEDLNKESK--EKQDLEKRVLELTSKLEK 567
+ ++ K++ I V E Q+ + ++SK E ++ K++ S++EK
Sbjct: 2409 EAENIERKKKELEIQKPAVYTETYMLETQKPVVEKSKTDELDEVRKKINADLSEVEK 2465
Score = 65.1 bits (157), Expect = 2e-07
Identities = 108/563 (19%), Positives = 242/563 (42%), Gaps = 74/563 (13%)
Frame = -3
Query: 2033 LNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIK- 1857
L++++ +K I + I+E +E + D++ K L+ E ++ D+ N +++
Sbjct: 11344 LDNKIQQTNLEKHDIEKSKEIVEKLMVEVEEQRKDIQLQKEELDIERQKIADEQNLLVQN 11403
Query: 1856 -----------KALDKRISDLKADAPQRD-----QEDDMNALIXXXXXXXXXXXXXXKIV 1725
K +D+ I + + + +++++ ++I +
Sbjct: 11404 KAKLQNENERIKKVDEEIKKERETLREMEIHLKKEKEELRSIIEETQRRKEDLEKMSTDI 11463
Query: 1724 SNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREE 1545
+ ++++ + L++E+++ + L ++ ++E + + + L + + EE
Sbjct: 11464 NEQKLHLKNQRDLLEQEREEINHEMTQL------QQRIDEFDAQVSKQREDLTKQEM-EE 11516
Query: 1544 EDEVLERSASNLAIMKAIRE-EELRKEKDGKS-----ALVENGEGCEAEKQGLEKTVLER 1383
E + LE + + + MK E +E+ +EK+ + +VE E E+ K+ L+R
Sbjct: 11517 ERKSLEETKARIIEMKTKAELQEIMQEKEEEDEEEMRVIVE----MEREELNQIKSELKR 11572
Query: 1382 RASNLDTMDAIHEEE--------LRKEKVD----KSALTENGEGCEAEKQGPEKTV--LD 1245
S +D HE++ + +EK D KS + + E E+ + + D
Sbjct: 11573 VRSEID-----HEQKKLNDDKKIIEQEKEDLEKMKSEIMTQRQQMEEERSELDNKIKQTD 11627
Query: 1244 LEP-TIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASN 1068
LE I + + +Q+ + +V +++ + + +L+ + + D Q G + + KL+ N
Sbjct: 11628 LERHDIENSKEIVQKLMVKVEEQRKDIRLQKEELDIERQKIADEQ-GLVVQNKAKLQNEN 11686
Query: 1067 ---LTHNDELHKEKDDKKSIMNDLDRVKAE-KQVLES----KVSDLETTYSTLNNELQQK 912
++E+ KEK+ K + L + K E + V+E K DLE + +N + Q
Sbjct: 11687 ERIKEMDEEIKKEKETLKEMEAHLRKEKEEMRSVIEETQRRKKEDLEKMSTDVNKQNQDL 11746
Query: 911 MDDNEAFLNERDGLEAVKQGLEKRVLDLEATI-----HDIEMKTGKDDDYNEAEKQTL-- 753
M+ + ER+ + L++R+ + +A + D+ + +++ E+ +
Sbjct: 11747 MNQRDLLKQEREEINHKWTQLQQRIDEFDAQVSKQKEEDLTKQKKMEEERKSLEETKIKI 11806
Query: 752 -------------KKRISELEEAISILTDKAKKLLKDINIWL----SEVTELQEDLNKES 624
K++ E EE + + K+ L I L SE+ Q+ LN +
Sbjct: 11807 IEMKTKTEPEKIKKEKEKEEEEVMRAKVEMKKEELDQIKSQLERVRSEIDHEQKKLNDDK 11866
Query: 623 K----EKQDLEKRVLELTSKLEK 567
K EK+DLEK E+ + ++
Sbjct: 11867 KMIEQEKEDLEKMKSEIMKQRQQ 11889
Score = 63.2 bits (152), Expect = 9e-07
Identities = 109/531 (20%), Positives = 210/531 (39%), Gaps = 36/531 (6%)
Frame = -3
Query: 2051 EAAIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDN 1872
E A +E+ N K++ K ++ ++L +A + +L + E KK+D+
Sbjct: 14466 EGEKARTTEEIHNLKEEIKRKSSELDMLNKEIEAKRQE-EELHGLPEEIEIEDHLKKEDD 14524
Query: 1871 ---NAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNIL 1701
IIKK + RD E + + + + I+
Sbjct: 14525 VLREEIIKKQQTDASQKFQLKTTSRDAETQTSLDEITKTDERRQRALEETVATTAKQPIV 14584
Query: 1700 I-----LHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDE 1536
I L E+Q+ +D IK+L + + + + +S ++ E F R E+
Sbjct: 14585 IKLEDTLTSEVQEMRDHLNNEIKELARMKTIMKMEKDQLKQAKSDIQTQMEEFERNMEEA 14644
Query: 1535 VLERSASNLAIMKAIRE-EELRKEKDGKSALVENGEGCEAEKQG-LEKTVL------ERR 1380
+ E+S + +++ + E+L D K+ +EN +K LE T++ E
Sbjct: 14645 MEEKSRNEEKLLQLTHDKEDLSNTLDKKNKEIENNTETFLKKIAQLETTIVLMKKDKENI 14704
Query: 1379 ASNLDTMDAIHEEELRKEKVD-----KSALTENGEGCEAEKQGPEKTVLDLEPTIPSLN- 1218
+ L + I +E + K D K TE + EK D + T+ +
Sbjct: 14705 ENELLQLKQIEQEREIQRKADVTSTEKEMYTEKVTYKTELEDSKEKIKPDRDSTLELTDT 14764
Query: 1217 DALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASNLTHNDELHKE 1038
D+ + D +R E Q LE + D+ T +QE E+E K++ EL+K
Sbjct: 14765 DSAKTDGER---EAQTLETKVQDVLQLTDDTTQDQEELHDEMENKMKIIL-----ELNKA 14816
Query: 1037 KDDKKSIMNDLDRVKAEKQVLESKVSDLETTYSTLNNELQQKMDDNEAFLNERDGLEAVK 858
K DL ++K E + E + S + + N L++ + + E D L +K
Sbjct: 14817 K-------KDLQKLKEECRSAEEEKSVIMESLERRRNSLEKVQSEVLSLTQEIDHLAQIK 14869
Query: 857 QGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKR---ISELEEAISILTDKAKKLL 687
+++ + ++ + + D + ++ ++ + EE IS K +
Sbjct: 14870 TEMQQIEIKMQIQTRSVATQWETDVQIQQEGQEPIETTGHITKKSEEEISAKKTKQPIVT 14929
Query: 686 KDINIWLSEVTELQEDLNKESK-----------EKQDLEKRVLELTSKLEK 567
K + SEV E+++ LNKE + EK LE+ ++ +++E+
Sbjct: 14930 KLEDTLTSEVQEMRDSLNKEMEDVARMKTIMKMEKDQLEQAKSDIQTQMEE 14980
Score = 62.8 bits (151), Expect = 1e-06
Identities = 107/536 (19%), Positives = 227/536 (42%), Gaps = 55/536 (10%)
Frame = -3
Query: 2027 DELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKAL 1848
+ L KD+ + +R+ LE K ++E NDE++++K + K L
Sbjct: 8374 ETLRGMKDEVQAARKERSELENMKLEFLTMKKNMEKTYEQQNDEIQKEKQQIESS-KMLL 8432
Query: 1847 DKRISDLKADAPQRDQED-----DMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEEL 1683
+ +DL+ + +++ D L+ KI+ NLE L EE
Sbjct: 8433 SRERNDLEQNRADLERQKQIMALDKQKLLAENELLEREKADVIKIIENLES----LREEA 8488
Query: 1682 QKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVLE--RSASNL 1509
+E+ +TA + +R E++ +E+ S E F +++++E R L
Sbjct: 8489 TRERATETA--------QATRRDSEELMQKMEALSM---EDFQEASKNQMVELKRQIDKL 8537
Query: 1508 AIMKAI---REEELRKEKDG-----------KSALVENGEGCEAEKQGLEKTVLERRASN 1371
+KA ++ EL+K K +S ++++ + +++ + LE ++R+ +
Sbjct: 8538 IELKADLLQQQTELKKTKADLKQQMDDLEKTRSEILKHEKDTDSKTRELELIEIQRQKDD 8597
Query: 1370 LDT------MDAIHEEELRKEKV-DKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLN-- 1218
L+T ++ E LR E V +K L + + ++ EK D+ +N
Sbjct: 8598 LETRIQKLTLEKRDLEVLRSEIVLEKKDLDQKMKQVIRKRDEMEKIRSDIANATEEINRE 8657
Query: 1217 ----DALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQE-------------GHEAEIE 1089
+ L+ ++ + + L +R ++LE + ++ TD + + E+E
Sbjct: 8658 RQELEILRNNVQSARHDFELLLERTANLEDEESAATDIERLVLEVVKIREMVRNLKGEME 8717
Query: 1088 RKLEASNLTHNDELHKEKDDKKSIMNDLDRVKAEKQVLESKVS-------DLETTYSTLN 930
R++E S + DE K + + + D+ +++ L ++ +LE + L
Sbjct: 8718 RRMEKSKV-EIDEKEIFKSEIQRFIQDIGQIRENLGGLGEEIEKTRRDKRELEKMRAELA 8776
Query: 929 NELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLK 750
+ Q++ E ER+ LE +K + + D+E +E K++ + Q K
Sbjct: 8777 EKQQEQESMREMLHKEREELEQLKDEINREKEDVEIRRELVEAVIDKEEMKEFTDIQKYK 8836
Query: 749 KRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLN-KESKEKQDLEKRVLEL 585
+ + + E +LT K+ L +N + ++ + E++N + K++ +LE EL
Sbjct: 8837 EELQSVTE--ELLT--KKRDLDQLNSDVQDLRQTIEEINIQHGKKRAELEGIGFEL 8888
Score = 62.8 bits (151), Expect = 1e-06
Identities = 118/583 (20%), Positives = 219/583 (37%), Gaps = 79/583 (13%)
Frame = -3
Query: 2081 QALESKVS-VFEAAIATLND--ELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKT 1911
Q LE+KV V + T D EL +E ++K I+ + N + Q L+ + E K+
Sbjct: 14776 QTLETKVQDVLQLTDDTTQDQEELHDEMENKMKIILELNKAKKDLQKLKEECRSAEEEKS 14835
Query: 1910 TLNDELERKKDDNNAIIKKALD-----KRISDLKADAPQ--------------------- 1809
+ + LER+++ + + L ++ +K + Q
Sbjct: 14836 VIMESLERRRNSLEKVQSEVLSLTQEIDHLAQIKTEMQQIEIKMQIQTRSVATQWETDVQ 14895
Query: 1808 -----RDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDKTALIKD 1644
++ + + IV+ LE L E+Q+ +D ++D
Sbjct: 14896 IQQEGQEPIETTGHITKKSEEEISAKKTKQPIVTKLEDT---LTSEVQEMRDSLNKEMED 14952
Query: 1643 LVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNLAIMKAIRE-EELRKE 1467
+ + + + + +S ++ E F R E+ + E+S + +++ + E+L
Sbjct: 14953 VARMKTIMKMEKDQLEQAKSDIQTQMEEFERNMEEAMEEKSRNEEKLLQLTHDKEDLSNT 15012
Query: 1466 KDGKSALVENG----------------------EGCEAEKQGLEKTVLERRASNLDTMDA 1353
D K+ +EN E E E L++T ER T D
Sbjct: 15013 LDKKNKEIENNTETSLKKIAQLETTIVLMKKDKENIENELLQLKQTEQEREIQR-GTDDT 15071
Query: 1352 IHEEELRKEKVD-KSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEK 1176
+E E EKV K+ L +N E +K+ + L L D+ + D +R E
Sbjct: 15072 SNEREKYDEKVTYKTELEDNKE----KKKPDRDSSLKLTDA-----DSAKTDGER---EA 15119
Query: 1175 QALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASNLTHNDELHKEKDDKKSIMNDLDRV 996
Q LE + D+ T +QE ELH E ++K I+ +L+
Sbjct: 15120 QTLETKVQDVLQLTDDTTQDQE-------------------ELHDEMENKMKIILELNEA 15160
Query: 995 KAEKQVLESKVSDLETTYSTLNNELQQKMDDNE-------AFLNERDGLEAVKQGLEKRV 837
K + Q L+ K E S + L+++ + E E + L +K +++
Sbjct: 15161 KKDLQKLKEKCRSAEEEKSVIMESLERRRNSLEKVQSEVLTLTQEIEHLAQIKTEMQQIE 15220
Query: 836 LDLEATIHDIEMKTGKDDDYNEAEKQTLKKR---ISELEEAISILTDKAKKLLKDINIWL 666
++ + + D + ++ + R + EE IS K + K +
Sbjct: 15221 TKMQRQTRSVATQWETDVQIQQEGQEATETRGHITKKSEEEISAKKTKQPTVTKLEDTLT 15280
Query: 665 SEVTELQEDLNKESK-----------EKQDLEKRVLELTSKLE 570
SEV E+++ LNKE + EK LE+ +L ++E
Sbjct: 15281 SEVQEMRDSLNKEMEDVERMKTMMKMEKDQLEQAKSDLQRQME 15323
Score = 62.4 bits (150), Expect = 2e-06
Identities = 121/544 (22%), Positives = 221/544 (40%), Gaps = 48/544 (8%)
Frame = -3
Query: 2081 QALESKVSVFEAAIATLNDELLNEKDDKKCIVNDRNILEAAKQ--ALEYKVADLEAAK-- 1914
Q L+++ + E + T ND LL E +K+ ND + E K+ ALE + D+ K
Sbjct: 14066 QLLQTEKEILEKS-KTEND-LLREDLEKQRKRNDLTLQELRKEKMALEQMITDITKEKDA 14123
Query: 1913 -TTLNDELERKKDD--NNAIIKKALDKRISDLKADAPQRD-----QEDDMNALIXXXXXX 1758
+L +E+ K+ + N K + DL+ R Q+ +++ I
Sbjct: 14124 VASLQNEVSLKQHELKNKETELDEQRKEMDDLRMQLEMRQNSTNKQQQEVDVFIVENMKM 14183
Query: 1757 XXXXXXXXKIVSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKS 1578
++LE +L EE ++ +D+ P K + LE +
Sbjct: 14184 R----------NDLESMKTLLDEERRQLQDNIKTFEDQKNVLHPSKTDAVQQTDELEKFT 14233
Query: 1577 RSLK---EHFLREEEDEVLERSASNLAIMKAIRE--------EELRKEKDGKSALVENGE 1431
+K EH +E E E N I+K+ E E ++E GK A +E+ E
Sbjct: 14234 TDIKTEKEHVEKERE----EIDVLNKEIIKSKEELQSLNLEIEMFKQEIAGKRAQIESLE 14289
Query: 1430 GCEAE----KQGLEKTVLERRASNLDTMDAIHEEELRKE-KVDKSALTENGEGCEAEKQG 1266
A+ ++ V + ++ + E EL+ + K+ L E EAEK
Sbjct: 14290 QLRADLLAGADDIKTLVQTEKQMAIEDTEKKTEVELQMNLQKQKNELEELRNTIEAEKHQ 14349
Query: 1265 PEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIER 1086
E + L+ + D + + +E+ LEK S+L + L + + + E+ER
Sbjct: 14350 VENRKIMLDKQQKEVEDIMTV----IKSERDVLEKEKSELNKLSHVLNEKVQREQEELER 14405
Query: 1085 KLEASNLTHNDELHKEKDDKKSIMNDLDRVKAEKQVLESKVSDLETTYSTLNNELQQKM- 909
LE KE+DD I N +++EKQ +E + ++L+ + + ++ +
Sbjct: 14406 LLE-----------KERDD---IENCKKIIESEKQSIERERAELKRLKEEVEVQHERTLL 14451
Query: 908 -DDNEAFLNERDGLEA-----------VKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAE 765
D E++ LE +K+ ++++ +L+ +IE K +++ + E
Sbjct: 14452 QQDKNMIQKEKEHLEGEKARTTEEIHNLKEEIKRKSSELDMLNKEIEAKRQEEELHGLPE 14511
Query: 764 ----KQTLKKRISELEEAI--SILTDKAKKL-LKDINIWLSEVTELQEDLNKESKEKQDL 606
+ LKK L E I TD ++K LK + T L E + + ++ L
Sbjct: 14512 EIEIEDHLKKEDDVLREEIIKKQQTDASQKFQLKTTSRDAETQTSLDEITKTDERRQRAL 14571
Query: 605 EKRV 594
E+ V
Sbjct: 14572 EETV 14575
Score = 60.5 bits (145), Expect = 6e-06
Identities = 105/514 (20%), Positives = 211/514 (41%), Gaps = 39/514 (7%)
Frame = -3
Query: 1985 NDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKALDKRISDLKADAPQR 1806
++ ++ EA Q AD+E ELE+ KD+ K + K DL+ +
Sbjct: 1701 DELSLREATLQTATQTTADMELQLELQKQELEQTKDEMER-TKLEVQKGWVDLQTQIAES 1759
Query: 1805 DQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDKTALIKDLVAAEP 1626
++++M + +++ + ++ E+ E D K L K+ E
Sbjct: 1760 REKEEMVRI---------ELEKARDVLNRIRQDVET--EKQTMEADLKFTLAKEFENLEA 1808
Query: 1625 GKRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNLAIMKAIREEELRKEKDGKSAL 1446
++ + + LE+ L + E +ERS N+ +E + ++ L
Sbjct: 1809 QRKMMEDEKRALENMKYEL------QRESGYIERSKHNM-------HDERQNMENWAEKL 1855
Query: 1445 VENGEGCEAEKQGLE--KTVLERRASNLDTMDAIHEEELRKEKVDKSAL-------TENG 1293
+ E E ++ ++ +T R +L+ + ++E L + K L ++
Sbjct: 1856 KQEWEELEKKRHDMQQLQTERSREIKDLENLRELNELTLNQIKTKSDVLEKISELNSQQK 1915
Query: 1292 EGCEAEKQGPEKTVLDLEPTIPSLN---DALQRDLDRVMAEKQALEKRCSDLEAKNASLT 1122
+ E EK + DL+ LN +Q + V EK L+K ++ + +
Sbjct: 1916 DEIENEKSKIKIREYDLQQMQTDLNRQQKEMQDIQNAVFMEKSELKKSQDEIAEQLKQVG 1975
Query: 1121 DNQEGHEAE-----------IERKLEAS-NLTH--NDELHKEKDDKKSIMNDLDRVKAEK 984
D + + E IE+KL+ ++TH N EL K KK ++N+ ++ +
Sbjct: 1976 DMMQFTQNEKDNLDRERAAIIEQKLQMERDMTHLLNRELESLKLVKKEVLNEKRLLEDCR 2035
Query: 983 QVLESKVSDLETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGL----EKRVLDLEA-- 822
L + DLE L E ++ ++ E+D LE+V Q L EK +D A
Sbjct: 2036 ISLMRDMQDLEQMKINLEREKEEMQLQRQSIAEEKDKLESVLQTLAEDTEKLRIDTLAEK 2095
Query: 821 -TIHD--IEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTE 651
+ D +E++ +D+ N AE+ KR E + I + +K + KD+ L +
Sbjct: 2096 QKLEDAAVELQKERDEIMNIAEE---TKRKREDVDKIRVGIEKQEITFKDLKADLQKEAA 2152
Query: 650 LQED----LNKESKEKQDLEKRVLELTSKLEKCI 561
+ E+ + K+ + +D+E ++ + +++ +
Sbjct: 2153 IVENQRQAVQKDIQNVKDMEVQIQKERQYMDRLV 2186
>gb|KFM76401.1| Myosin heavy chain, non-muscle, partial [Stegodyphus mimosarum]
Length = 1966
Score = 103 bits (256), Expect = 8e-19
Identities = 120/501 (23%), Positives = 223/501 (44%), Gaps = 35/501 (6%)
Frame = -3
Query: 1967 EAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIK--KALDKRISDL-KADAPQRDQE 1797
EAA+Q L+ + +L++ + ++ +D N ++K K L++R+ ++ +A A + ++
Sbjct: 959 EAARQKLQLEKVNLDSKIKKIEEDYAVLEDSNQKVVKEKKTLEERLGEVSQALAEEEEKS 1018
Query: 1796 DDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKR 1617
++ L + E I+ L E +KE+ + L + E
Sbjct: 1019 KHLSKL-----------------KAKQEATIIDLEERHRKEQQARQELERVKRRIETELN 1061
Query: 1616 TVNEIVSHLESKSRSLKEHFLREEED------EVLERSASNLAIMKAIRE-----EELRK 1470
V E ++ + + L + R+EE+ E +A ++K++RE EL++
Sbjct: 1062 DVKEQLNEKKIEVEELHQQLARKEEELNQSLLRCDEEAAGKAQVLKSLREIESQLSELQE 1121
Query: 1469 EKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIH-EEELRKEKVDKSALTENG 1293
+ D + + E +K+ L + + R LD+ + H +E+LR ++ + A+ +
Sbjct: 1122 DLDSER---QTRAKVEKQKRDLNEELEALRNELLDSAENTHAQEDLRTKREQELAMLK-- 1176
Query: 1292 EGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQ 1113
+ + E Q E + DL + L LD V K +LEK + LEA+ A LT+
Sbjct: 1177 KTLDEETQSHEAQIADLRQKHNLAIENLNEQLDIVKKAKGSLEKAKAHLEAEKAELTNEV 1236
Query: 1112 EGHEA---EIERKLEASNLTHNDELHKEKDDKKS----------IMNDLDRVKAEKQVLE 972
A + ERK + L + K D +KS + +LD V A+ + L+
Sbjct: 1237 NALSAARQDSERKRKQLELQLQELGAKLSDAEKSRTDNIEKVQKLQAELDSVSAQLEELD 1296
Query: 971 SKVSDLETTYSTLNNELQQKMD------DNEAFLNER-DGLEAVKQGLEKRVLDLEATIH 813
+K + + L +L + D + LN R LE K+ L++++ + E
Sbjct: 1297 TKATAATKQAAVLEGQLAEAQDLLQEETRQKLALNSRLRQLENEKENLQEQLDEEEEAKK 1356
Query: 812 DIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLN 633
++E K A+ Q LKKR E + ++ L + KK KDI + ++ ELQ +
Sbjct: 1357 NLE----KQVSLLNAQLQELKKRADEDAQQVANLEEVRKKQTKDIEMLQRQIEELQTAND 1412
Query: 632 KESKEKQDLEKRVLELTSKLE 570
K SK K+ L+ V +L +LE
Sbjct: 1413 KLSKSKKKLQSEVEDLNMELE 1433
Score = 79.7 bits (195), Expect = 9e-12
Identities = 121/523 (23%), Positives = 220/523 (42%), Gaps = 20/523 (3%)
Frame = -3
Query: 2075 LESKVSVFEAAIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDE 1896
LE K+ TL ++L E + R L A KQ LE + DLEA E
Sbjct: 874 LEKKLQKVVEEKNTLAEQLQAETELCAEAEEMRLRLAARKQELEEILHDLEA-----RIE 928
Query: 1895 LERKKDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNL 1716
E +++ N KK L I DL+ Q ++E+ + NL
Sbjct: 929 EEEERNQNLTAEKKKLQLNIQDLEE---QLEEEEAARQKLQLEKV-------------NL 972
Query: 1715 EVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDE 1536
+ I + E+ +D ++K+ E V++ ++ E KS+ L + ++E
Sbjct: 973 DSKIKKIEEDYAVLEDSNQKVVKEKKTLEERLGEVSQALAEEEEKSKHLSK-LKAKQEAT 1031
Query: 1535 VLERSASNLAIMKAIREEELRKEK------DGKSALVENGEGCEAEKQGLEKTVLERRAS 1374
+++ + +A +E E K + D K L E E Q L + E S
Sbjct: 1032 IIDLEERHRKEQQARQELERVKRRIETELNDVKEQLNEKKIEVEELHQQLARKEEELNQS 1091
Query: 1373 NL--DTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGP---EKTVLDLEPTIPSLNDAL 1209
L D A + L+ + +S L+E E ++E+Q EK DL + +L + L
Sbjct: 1092 LLRCDEEAAGKAQVLKSLREIESQLSELQEDLDSERQTRAKVEKQKRDLNEELEALRNEL 1151
Query: 1208 QRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASNLTHNDELHKEKDD 1029
+ A++ KR +L +L + + HEA+I + NL + L+++ D
Sbjct: 1152 LDSAENTHAQEDLRTKREQELAMLKKTLDEETQSHEAQIADLRQKHNLAI-ENLNEQLDI 1210
Query: 1028 KKSIMNDLDRVKAEKQVLESKVSDLETTYSTLNNELQQKMDDNEAFLNE-----RDGLEA 864
K L++ KA + ++++++ S + ++K E L E D ++
Sbjct: 1211 VKKAKGSLEKAKAHLEAEKAELTNEVNALSAARQDSERKRKQLELQLQELGAKLSDAEKS 1270
Query: 863 VKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLLK 684
+EK V L+A + + + + D A + +L EA +L ++ ++ L
Sbjct: 1271 RTDNIEK-VQKLQAELDSVSAQLEELDTKATAATKQAAVLEGQLAEAQDLLQEETRQKLA 1329
Query: 683 DINIWL----SEVTELQEDLNKESKEKQDLEKRVLELTSKLEK 567
+N L +E LQE L++E + K++LEK+V L ++L++
Sbjct: 1330 -LNSRLRQLENEKENLQEQLDEEEEAKKNLEKQVSLLNAQLQE 1371
Score = 78.2 bits (191), Expect = 3e-11
Identities = 107/529 (20%), Positives = 229/529 (43%), Gaps = 35/529 (6%)
Frame = -3
Query: 2051 EAAIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDN 1872
E+ ++ L ++L +E+ + + + L +AL ++ D A T ++L K++
Sbjct: 1113 ESQLSELQEDLDSERQTRAKVEKQKRDLNEELEALRNELLD-SAENTHAQEDLRTKREQE 1171
Query: 1871 NAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILH 1692
A++KK LD+ +A Q+ ++ + NL +
Sbjct: 1172 LAMLKKTLDEETQSHEAQIADLRQKHNL-------------------AIENL-------N 1205
Query: 1691 EELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASN 1512
E+L K K +L K E K + V+ L + + + R++ + L+ +
Sbjct: 1206 EQLDIVKKAKGSLEKAKAHLEAEKAELTNEVNALSAARQDSERK--RKQLELQLQELGAK 1263
Query: 1511 LAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHEEELR 1332
L+ + R + + K + ++ L + + E+ + T ++A+ L+ A ++ L+
Sbjct: 1264 LSDAEKSRTDNIEKVQKLQAEL--DSVSAQLEELDTKATAATKQAAVLEGQLAEAQDLLQ 1321
Query: 1331 KEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCS 1152
+E K AL E EK+ ++ + + E +L ++ + + A+ Q L+KR
Sbjct: 1322 EETRQKLALNSRLRQLENEKENLQEQLDEEEEAKKNL----EKQVSLLNAQLQELKKRAD 1377
Query: 1151 DLEAKNASLTDNQEGHEAEIE---RKLEASNLTHNDELHKEKDDKKSIMNDLDRVKAEKQ 981
+ + A+L + ++ +IE R++E T ND+L K K K + ++++ + E +
Sbjct: 1378 EDAQQVANLEEVRKKQTKDIEMLQRQIEELQ-TANDKLSKSK---KKLQSEVEDLNMELE 1433
Query: 980 VLESKVSDLETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEM 801
+KVS+LE + L ++ +E ERD E + E ++L L D +
Sbjct: 1434 NQRTKVSELEKKQRKFDQLLAEEKAVSERIAQERDNAERESREKETKILSLTRAYEDCQD 1493
Query: 800 KTGK----------------------DDDYNEAE--KQTLKKRISELEEAISILTDKAK- 696
K + D + +E E K+ L+ ++++ ++ +L D+ +
Sbjct: 1494 KMEELERSRKQLQLELEELVSSQGTADKNVHELEKAKRALESQLADQKDQFELLEDEMQL 1553
Query: 695 ----KLLKDINIWLSEV---TELQEDLNKESKEKQDLEKRVLELTSKLE 570
KL ++N+ + +LQ + ++++ L K+V EL S+LE
Sbjct: 1554 TEDAKLRLEVNMQAMKAQFERDLQAKDEQAEEKRRALLKQVRELESELE 1602
Score = 68.9 bits (167), Expect = 2e-08
Identities = 103/522 (19%), Positives = 206/522 (39%), Gaps = 27/522 (5%)
Frame = -3
Query: 2069 SKVSVFEAAIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELE 1890
+KVS E + L EK + I +R+ E + E K+ L A D++E
Sbjct: 1437 TKVSELEKKQRKFDQLLAEEKAVSERIAQERDNAERESREKETKILSLTRAYEDCQDKME 1496
Query: 1889 RKKDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEV 1710
+ +K L + +L + D+ V LE
Sbjct: 1497 ELERS-----RKQLQLELEELVSSQGTADKN-----------------------VHELEK 1528
Query: 1709 NILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVL 1530
L +L +KD L ++ E K LE +++K F R+ + +
Sbjct: 1529 AKRALESQLADQKDQFELLEDEMQLTEDAKL-------RLEVNMQAMKAQFERDLQAKDE 1581
Query: 1529 ERSASNLAIMKAIRE--EELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMD 1356
+ A++K +RE EL E+ ++A + + E + + LE+ L+ +
Sbjct: 1582 QAEEKRRALLKQVRELESELEDERKQRTAAISARKKVEGDLKDLEQ--------QLELAN 1633
Query: 1355 AIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEK 1176
+ E+ LR+ K +S L + EA+ E+ L L+ L ++ D+ +V +
Sbjct: 1634 RVKEDALRQLKKLQSQLKDYQRDAEADHAAKEELSLQLKEVEKKLK-LMEADMIQVQEDL 1692
Query: 1175 QALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASNLTHNDELHKEKDDKKSIMNDLDRV 996
E+ EA+ L + EI + +L DE + + + + +L+
Sbjct: 1693 ANSERIRRAAEAERDELQE-------EINTTVSRGSLLQ-DEKRRLEARIQQLEEELEEE 1744
Query: 995 KAEKQVLESKVSDLETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLE--- 825
++ ++L K + L N+L + +++ N R LE + L ++ DLE
Sbjct: 1745 QSNSEILMDKARKAQGQIEQLTNDLASERSNSQKLENNRMILERQNKELRAKLQDLETSQ 1804
Query: 824 -----ATIHDIEMKTGKDD---DYNEAEKQTLKKRISELEEAISIL----------TDKA 699
ATI +E K + + D E+Q K +LE+ + + TD+
Sbjct: 1805 RTRTKATIAALEAKVAQVEEQLDMETKERQLQAKANRKLEKRLKEVLMQLEDERRHTDQY 1864
Query: 698 KKLLKDINIWLS----EVTELQEDLNKESKEKQDLEKRVLEL 585
K+ ++ +N + ++ E +E+ ++E +++ ++ + +L
Sbjct: 1865 KEQVEKMNARVKALKRQLDESEEECSREKAQRRKAQREIEDL 1906
>ref|XP_005159743.1| PREDICTED: nesprin-1 isoform X6 [Danio rerio]
Length = 15134
Score = 103 bits (256), Expect = 8e-19
Identities = 128/547 (23%), Positives = 231/547 (42%), Gaps = 48/547 (8%)
Frame = -3
Query: 2033 LNDELLNEKDDKKCIVND----RNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNA 1866
+ +EL EK+ + D + IL+ K A E +ADL+ K+ L + E
Sbjct: 4152 MTEELKKEKESFTHLAEDTKTEKKILDKMKVANESLMADLQKEKSNLEEMRENISKQTED 4211
Query: 1865 IIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEE 1686
K+ R+ + + + Q + + K V +L+ + L +
Sbjct: 4212 SEKEKEKIRLREDELEQLQAEIHKQQGEIKMEKSNNESERAAIIKDVKDLQHKMFSLDRD 4271
Query: 1685 LQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVL-------- 1530
L+ K D+ A E + + +I + L+ K+ +++ L + D
Sbjct: 4272 LESLKLDREAF-------ENEREVLKQIKTDLKRKAEEIEKIKLETQHDRQRVEEMTAQI 4324
Query: 1529 --ERSASNLAIMKAIREEELRKE-----KDGKSALVENGEGCEAEKQGLEKT--VLERRA 1377
ER N I + R++ + E K+ A+ + + E EK LEKT L R
Sbjct: 4325 QKERDKINNLIEETNRKDMVLNEIKTEIKEKIKAIESDRDMLEKEKHDLEKTRSKLLRAK 4384
Query: 1376 SNLDTMDAIHEEELRKEKVDKSALTE------NGEGCEAEKQGPEKTVLD-LEPTIPSLN 1218
NL+ I E++KE+ D + E + + E+ ++ LD L+ I +L
Sbjct: 4385 ENLEKQRKIKLAEIQKEREDLEKMNEKFTIEIHDIKHQEEQMKQKQDELDQLKTEIQNLQ 4444
Query: 1217 DALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIER--KLEASNLTHNDELH 1044
L+++ + +M ++ L+ R S+L+ + ++ D E + E ++ K + E+
Sbjct: 4445 QELEKEKEIIMKDRSQLDLRQSELDKQQTNVNDIMETMKNERKQLDKDKEETEEQKQEME 4504
Query: 1043 KEKDD----KKSIMNDLDRVKAEKQVLESKVSDLETTYSTLNNELQQKMDDNEAFLNERD 876
KEK D +KS+ DL +K +KQVLE + S LE L E + E NER
Sbjct: 4505 KEKHDFDQSRKSLDEDLKMMKLQKQVLEDEKSKLEQMKIELEREAVEIRKIKEEIQNERQ 4564
Query: 875 GLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTL------KKRISELEEAISI 714
LE + + L++ DL + + D+ A + TL K + E+ E IS
Sbjct: 4565 NLEKMTEALKEEREDL---AEETKKNNQVLDEMKVANESTLADILREKSNLEEMRENISK 4621
Query: 713 LTDKAKKLLKDINIWLSEVTELQEDLNKE----SKEKQDLEKRVLELTSKLE----KCIC 558
T+ + +++ + E+ +LQ +++K+ KEK ++E + +E K IC
Sbjct: 4622 QTEDVENKKENLRLREDELRQLQAEIHKQQREIEKEKINIESERAAIIKDVEDLQHKIIC 4681
Query: 557 GARDGLS 537
RD S
Sbjct: 4682 LDRDAES 4688
Score = 100 bits (248), Expect = 7e-18
Identities = 131/576 (22%), Positives = 258/576 (44%), Gaps = 33/576 (5%)
Frame = -3
Query: 2027 DELLNEKDDK-----KCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAI 1863
D +LNEK+ K I +D+++LE K LE ++L K ++LE++K++ A
Sbjct: 5629 DMVLNEKNRDIEKKIKSIQSDKDMLEKEKHDLEKTRSELYKVK----EDLEKQKENTLAQ 5684
Query: 1862 IKKA---LDKRISDLKADAPQ-RDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILIL 1695
I+K L+K ++ + + + QE+ MN + L+ I L
Sbjct: 5685 IQKEREDLEKMNENITREMHEIKHQEEQMNQ--------------KQDELDQLKTEIQNL 5730
Query: 1694 HEELQKEKD----DKTALIKDLVAAEPGKRTVNEIVSHLESKSRSL-KEHFLREEEDEVL 1530
+EL+KEK+ ++ L + + + +N+I+ ++++ + L K+ EE+ + +
Sbjct: 5731 QQELEKEKEIIMKARSQLDRRQSELDKQQTNMNDIMETMKNERKQLDKDKEEMEEQKQEM 5790
Query: 1529 ERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAI 1350
E+ N+ + +E+L+ K K + E E K LE+ + R +T +
Sbjct: 5791 EKERDNMDQSRKSLDEDLKMMKLQKQVIEEEKNKLEQMKIELEREADDIRKIKEETQNKR 5850
Query: 1349 H-----EEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVM 1185
EEL+KE+ D + L E+ + EK ++ + E ++ L Q++ +
Sbjct: 5851 QILEKMAEELKKERKDVAHLAED---TKREKNSLDEMKVANESSMADL----QKEKSNLE 5903
Query: 1184 AEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASNLTHNDELHKEKDDKKSIMNDL 1005
K+ + K+ D+E + D E E+E+ L+A E+HK++ + + +++
Sbjct: 5904 EMKENISKQTEDIEKEK----DKIRLREDELEQ-LQA-------EIHKQQSETEIEKSNI 5951
Query: 1004 DRVKAEKQVLESKVSDLETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLE 825
+R E+ + V DL++ +L+ + + D EAF NE++ L+ +K LE+ ++E
Sbjct: 5952 ER---ERAAIIKDVEDLQSKIISLDRDAESLKLDREAFENEKEELKQMKTELEREADEIE 6008
Query: 824 ----ATIHD----IEMKTGKDDDYNEAEKQTLKKRI------SELEEAISILTDKAKKLL 687
T H+ EM + N KQ K ++ E+E+ + K L
Sbjct: 6009 KIKLETQHERQRVEEMTADFMETMNNERKQLDKNKVMIEEQKQEMEKKRDDMDQSRKSLD 6068
Query: 686 KDINIWLSEVTELQEDLNKESKEKQDLEKRVLELTSKLEKCICGARDGLSTIKEAWMSDC 507
+D+ + ++ L+E+ NK + K LE+ E+ SK+++ R L + A +
Sbjct: 6069 EDLKMMKAQKQVLEEEKNKLEQMKIGLEREADEI-SKIKEETQNERQNLEKMANALKEE- 6126
Query: 506 MVPDNWVPFEDLVQGFSRKTSPLDITKTCDAVDISE 399
E L + RK LD K + +++
Sbjct: 6127 --------REYLAEEIKRKNQVLDKIKVANESTLAD 6154
Score = 97.1 bits (240), Expect = 6e-17
Identities = 130/534 (24%), Positives = 241/534 (45%), Gaps = 47/534 (8%)
Frame = -3
Query: 2027 DELLNE-----KDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLND-------ELERK 1884
D +LNE K+ K I +DR++LE K LE + L AK L E++++
Sbjct: 4342 DMVLNEIKTEIKEKIKAIESDRDMLEKEKHDLEKTRSKLLRAKENLEKQRKIKLAEIQKE 4401
Query: 1883 KDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNI 1704
++D + +K I D+K Q Q+ D + L+ I
Sbjct: 4402 REDLEKMNEK-FTIEIHDIKHQEEQMKQKQDE--------------------LDQLKTEI 4440
Query: 1703 LILHEELQKEKD----DKTALIKDLVAAEPGKR--TVNEIVSHLESKSRSL-KEHFLREE 1545
L +EL+KEK+ D++ L DL +E K+ VN+I+ ++++ + L K+ EE
Sbjct: 4441 QNLQQELEKEKEIIMKDRSQL--DLRQSELDKQQTNVNDIMETMKNERKQLDKDKEETEE 4498
Query: 1544 EDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLD 1365
+ + +E+ + + +E+L+ K K L + E K LE+ +E R
Sbjct: 4499 QKQEMEKEKHDFDQSRKSLDEDLKMMKLQKQVLEDEKSKLEQMKIELEREAVEIRKIK-- 4556
Query: 1364 TMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVM 1185
+ I E EK+ + AL E E E + + + +++ S + R+ +
Sbjct: 4557 --EEIQNERQNLEKMTE-ALKEEREDLAEETKKNNQVLDEMKVANESTLADILREKSNLE 4613
Query: 1184 AEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASNLTHNDELHKEKDDKKSIMNDL 1005
++ + K+ D+E K +N E E+ R+L+A E+HK++ + I +
Sbjct: 4614 EMRENISKQTEDVENKK----ENLRLREDEL-RQLQA-------EIHKQQ---REIEKEK 4658
Query: 1004 DRVKAEKQVLESKVSDLETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLE 825
+++E+ + V DL+ L+ + + D EAF NE++ L+ +K LE+ ++E
Sbjct: 4659 INIESERAAIIKDVEDLQHKIICLDRDAESLKLDREAFENEKEVLKQMKTELEREADEIE 4718
Query: 824 ----ATIHD--------IEMKTGKDDDYNEAEK-----QTLKKRISELEEAI-SILTDK- 702
T HD +++ +D+ N E+ L ++ ++EE I SI +DK
Sbjct: 4719 KIKLETQHDRQRVEEMAAQIQKDRDEINNLIEETNRKDMVLNEKNRDIEEKIKSIQSDKD 4778
Query: 701 -AKKLLKDINIWLSEVTELQEDLNKE--------SKEKQDLEKRVLELTSKLEK 567
+K D+ SE+ +++EDL K+ KE++DLEK +T ++ +
Sbjct: 4779 MLEKEKHDLEKTRSELYKVKEDLEKQKENTLAEIQKEREDLEKMNENITREMHE 4832
Score = 93.2 bits (230), Expect = 8e-16
Identities = 131/541 (24%), Positives = 244/541 (45%), Gaps = 54/541 (9%)
Frame = -3
Query: 2027 DELLNEKDDK-----KCIVNDRNILEAAKQALE------YKVA-DLEAAKTTLNDELERK 1884
D +LNEK+ K I +D+++LE + LE YKV DLE K E++++
Sbjct: 5212 DMVLNEKNRDIEEKIKSIQSDKDMLEKERHNLEKTRSELYKVKEDLEKQKENTLAEIQKE 5271
Query: 1883 KDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNI 1704
++D + + + + + ++K Q +Q+ D + L+ I
Sbjct: 5272 REDVEKM-NENITREMHEIKHQEEQMNQKQDE--------------------LDQLKTEI 5310
Query: 1703 LILHEELQKEKD----DKTALIKDLVAAEPGKR--TVNEIVSHLESKSRSL-KEHFLREE 1545
L +EL+KEK+ D++ DL +E K+ +N+I+ ++++ + L K+ EE
Sbjct: 5311 QNLQQELEKEKEIIMKDRSQF--DLRQSELDKQQTNMNDIMETMKNERKQLDKDKEEMEE 5368
Query: 1544 EDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLD 1365
+ + +E+ + + +++L+ K K E E K LE+ E R +
Sbjct: 5369 QKQEMEKEKHDFDQSRKSLDKDLKMMKLQKQVFEEEKNKLEQMKIELEREADEIRKIKEE 5428
Query: 1364 TMDAIHE-----EELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRD 1200
T + EEL+KEK + L E+ + E+ +LD + N++L D
Sbjct: 5429 TQNERQSLEKMTEELKKEKESFTHLAEDTK--------KEQEILD---KVKVANESLMAD 5477
Query: 1199 LDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIER--KLEASNLTHNDELHKEKDDK 1026
L + EK LE+ ++ + + + +E + +L+A E+ KEK +
Sbjct: 5478 LQK---EKSNLEEMRENISKQTEDVENKKENLRLREDELWQLQAEIYKQQREIEKEKIN- 5533
Query: 1025 KSIMNDLDRVKAEKQVLESKVSDLETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLE 846
+++E+ + V DL+ +L+ + + D EAF NER+ L+ +K LE
Sbjct: 5534 ---------IESERAAIIKNVEDLQHKIISLDRDSESLKLDREAFENEREVLKQMKTELE 5584
Query: 845 KRVLDLE----ATIHD---IEMKTG---KD-DDYNEAEKQT------LKKRISELEEAI- 720
+ ++E T HD +E T KD D N ++T L ++ ++E+ I
Sbjct: 5585 READEIEKIKLETQHDRQRVEEMTAQIQKDRDKINNLIEETNRKDMVLNEKNRDIEKKIK 5644
Query: 719 SILTDK--AKKLLKDINIWLSEVTELQEDLNKE--------SKEKQDLEKRVLELTSKLE 570
SI +DK +K D+ SE+ +++EDL K+ KE++DLEK +T ++
Sbjct: 5645 SIQSDKDMLEKEKHDLEKTRSELYKVKEDLEKQKENTLAQIQKEREDLEKMNENITREMH 5704
Query: 569 K 567
+
Sbjct: 5705 E 5705
Score = 92.8 bits (229), Expect = 1e-15
Identities = 125/547 (22%), Positives = 240/547 (43%), Gaps = 48/547 (8%)
Frame = -3
Query: 2081 QALESKVSVFEAAIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADL-----EAA 1917
+ LES + + + L +LL + D + + DR +LE K+ L+ DL E
Sbjct: 3639 ELLESDRKLLKKDVENLQQKLLIIESDSESLKQDRELLENEKEVLKQMKTDLQGEAEEIE 3698
Query: 1916 KTTLNDELERKK-DDNNAIIKKA----------LDKRISDLKADAPQRDQEDDMNALIXX 1770
K L + ER++ ++ A I+K + + I D+K Q Q+ D
Sbjct: 3699 KIKLETQHERQRVEEMTAQIQKDREYLQKMNDNITREIHDIKYQEKQMKQKQDE------ 3752
Query: 1769 XXXXXXXXXXXXKIVSNLEVNILILHEELQKEKD----DKTALIKDLVAAEPGKR--TVN 1608
+ L+ I L +EL+KEK+ D++ L DL +E K+ +N
Sbjct: 3753 --------------LDQLKTEIQNLQQELEKEKEIIMKDRSEL--DLKQSELDKQQTNMN 3796
Query: 1607 EIVSHLESKSRSL-KEHFLREEEDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGE 1431
+I+ ++++ + L K+ EE+ +E+ + + +E+L+ K K
Sbjct: 3797 DIIETMKNERKQLDKDKEEMEEQKREIEKEKHDFDQGRNSLDEDLKMMKLQKQVF----- 3851
Query: 1430 GCEAEKQGLE--KTVLERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCE------AE 1275
E EK LE K LER A + + +EE++ E+ +TE + + AE
Sbjct: 3852 --EEEKNKLEQMKIELEREAGEIRKI----KEEIQNERQSLEKMTEELKREKESFTHLAE 3905
Query: 1274 KQGPEKTVLD-LEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAK--NASLTDNQEGH 1104
E+ +LD ++ SL LQ++ ++ + K+ D++ K N L +++ G
Sbjct: 3906 DTKKEQEILDEIKVANESLMAELQKEKSNFEEMRENISKQTEDVKNKKENLRLREDELG- 3964
Query: 1103 EAEIERKLEASNLTHNDELHKEKDDKKSIMNDLDRVKAEKQVLESKVSDLETTYSTLNNE 924
+L+A E+HK++ + I + +++E+ + V DL+ +L+ +
Sbjct: 3965 ------QLQA-------EIHKQQ---REIEKEKSNIESERAAIIKIVEDLQHKIISLDRD 4008
Query: 923 LQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLE----ATIHDIEMKTGKDDDYNEA---- 768
+ D EAF NER+ L+ +K LE+ ++E T H+ + D+ E
Sbjct: 4009 AESLKLDREAFENEREVLKQMKTELERETDEIEKIKLETQHERQRVEEMTADFMETMNNE 4068
Query: 767 ------EKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDL 606
K+ ++++ E+E+ + K L K++ + + ++E+ NK + K +L
Sbjct: 4069 RKQLNKNKEEMQEQKQEMEKERHDMDQSRKSLDKNLKMMKLQKQVIEEEKNKLEQMKIEL 4128
Query: 605 EKRVLEL 585
EK E+
Sbjct: 4129 EKEADEI 4135
Score = 89.0 bits (219), Expect = 2e-14
Identities = 123/538 (22%), Positives = 234/538 (43%), Gaps = 24/538 (4%)
Frame = -3
Query: 2081 QALESKVSVFEAAIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLN 1902
Q +E + E A L E + + ++ I NDR E L+ + D+E + +
Sbjct: 2805 QIIEDERDKIEQIKAELQKEAKDTEKQRQDIENDRRNNEEMVIKLQNEKKDIETSTDRIR 2864
Query: 1901 DE-------LERKKDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXX 1743
DE +R + D + + K+ D + K + +D E + +
Sbjct: 2865 DEEANLRVLKQRLESDRDTLEKERFDLK----KTNTEMKDLEKQLESQNRQHEIQLAEIQ 2920
Query: 1742 XXXKIVSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKE 1563
+I+ L++ + E+L+KE+D D+ E E+ E +
Sbjct: 2921 KEREILEQLKLTLSKQKEDLEKERDCFEKEKADISLRE-------ELQEQSEREGIGKTR 2973
Query: 1562 HFLREEEDEVLE------RSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLE 1401
+++E DE+ + + N + K I E+E K + K+ L + E E +++ +E
Sbjct: 2974 VRIKKEMDELKQTRLNVVKELENNELQKQIIEDERDKIEQIKAELQKEAEDTEKQRRDIE 3033
Query: 1400 K---------TVLERRASNLDT-MDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTV 1251
K L+ +++T D I +EE E V K L + + E E+ EKT
Sbjct: 3034 KDRRNNEEMVIKLQNEKKDIETSTDRIRDEEANLE-VQKQRLESDRDTLEKERFDLEKTK 3092
Query: 1250 LDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIE-RKLEA 1074
++ +L L+ + + + ++K LE +L+ +E E E + + E
Sbjct: 3093 TEM----GNLKKQLESQIRQHEIQLVEIQKEREILEQLKINLSKQKEDLEKERDCFEKEK 3148
Query: 1073 SNLTHNDELHKEKDDKKSIMNDLDRVKAEKQVLESKVSDLETTYSTLNNELQQKMDDNEA 894
++++ +++L KE+ +++ I N R+K E LE +L NNELQ+K+ +
Sbjct: 3149 ADISLSEDL-KEQSEREGIDNTRTRIKQEMDELEKTRQNLAKEQE--NNELQKKIIE--- 3202
Query: 893 FLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISI 714
+ERD +E +K L+K EA +E+ +++ N E T K+ E E+++
Sbjct: 3203 --DERDKIEQIKAELKK-----EAEKTKLEL---QNERQNLEEAGTKLKKDRENVESLAE 3252
Query: 713 LTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLELTSKLEKCICGARDGL 540
+ + +L+++ I TE+Q N+ +K+ Q+ RVL K I GA++ L
Sbjct: 3253 ELGRKQVVLENMQI----ETEMQRKANESNKQMQE---RVLIELKKTVTDIAGAKEDL 3303
Score = 88.2 bits (217), Expect = 3e-14
Identities = 122/534 (22%), Positives = 228/534 (42%), Gaps = 35/534 (6%)
Frame = -3
Query: 2042 IATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAI 1863
I+ L + + NEK+ K ++ L+ Q + K+ D+E KT + E A
Sbjct: 5036 ISKLKEYIDNEKEKSKLREDELKKLQTEVQKQQSKI-DME--KTNIESE--------RAA 5084
Query: 1862 IKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEEL 1683
+ + +++LK + D E M ++ + V NL+ ++ L +
Sbjct: 5085 MIREKQNMMTELKKKS--EDVEIQMKEILTEKELLHNDRKLLTRDVENLQQKLIDLERDS 5142
Query: 1682 QKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVL---ERSASN 1512
++ K D+ A + A + K + +E + R EE ER N
Sbjct: 5143 KRLKLDREAFENEKEAMKQMKTDLQIQADEIEKIKLETQHDRQRVEEMAAQIQKERDKIN 5202
Query: 1511 LAIMKAIREEELRKEKDGK-----SALVENGEGCEAEKQGLEKTV---------LERRAS 1374
I + R++ + EK+ ++ + + E E+ LEKT LE++
Sbjct: 5203 NLIEETNRKDMVLNEKNRDIEEKIKSIQSDKDMLEKERHNLEKTRSELYKVKEDLEKQKE 5262
Query: 1373 NLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKT--VLDLEPTIPSLNDALQRD 1200
N T+ I +E EK++++ E E E+Q +K + L+ I +L L+++
Sbjct: 5263 N--TLAEIQKEREDVEKMNENITREMHEIKHQEEQMNQKQDELDQLKTEIQNLQQELEKE 5320
Query: 1199 LDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIER--KLEASNLTHNDELHKEKDD- 1029
+ +M ++ + R S+L+ + ++ D E + E ++ K + E+ KEK D
Sbjct: 5321 KEIIMKDRSQFDLRQSELDKQQTNMNDIMETMKNERKQLDKDKEEMEEQKQEMEKEKHDF 5380
Query: 1028 ---KKSIMNDLDRVKAEKQVLESKVSDLETTYSTLNNELQQKMDDNEAFLNERDGLEAVK 858
+KS+ DL +K +KQV E + + LE L E + E NER LE +
Sbjct: 5381 DQSRKSLDKDLKMMKLQKQVFEEEKNKLEQMKIELEREADEIRKIKEETQNERQSLEKMT 5440
Query: 857 QGLEKRVLDLEATIHDIEMKTGKDDDY-------NE---AEKQTLKKRISELEEAISILT 708
+ L+K + E+ H E T K+ + NE A+ Q K + E+ E IS T
Sbjct: 5441 EELKK---EKESFTHLAE-DTKKEQEILDKVKVANESLMADLQKEKSNLEEMRENISKQT 5496
Query: 707 DKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLELTSKLEKCICGARD 546
+ + +++ + E+ +LQ ++ K+ +E +EK + + S+ I D
Sbjct: 5497 EDVENKKENLRLREDELWQLQAEIYKQQRE---IEKEKINIESERAAIIKNVED 5547
Score = 87.0 bits (214), Expect = 6e-14
Identities = 104/492 (21%), Positives = 228/492 (46%), Gaps = 21/492 (4%)
Frame = -3
Query: 2012 EKDDKKCIVNDRNI----LEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKALD 1845
EKD K N++N+ L A + L+ + A++E K L + ++R + + I K+
Sbjct: 2487 EKDRLKLQENEQNMQMSQLNAKQNELDERQAEMEKQKRELENVMDRLEKEKVEITKEK-- 2544
Query: 1844 KRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDD 1665
+R+++++ + +++ D+ + ++E + IL+ EL+K K+
Sbjct: 2545 QRVNEMQNEVKRKNASVDL------------IKQEVLREQDHIENSREILNRELEKIKEK 2592
Query: 1664 KTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNLAIMKAIRE 1485
KT L ++ A + K + + + L L ++E E E+ ++ + E
Sbjct: 2593 KTILAEEFEALDDKKEMIGKEMQRLGKMKAEL------QKEAEDTEKQRRDIDNDRRNNE 2646
Query: 1484 EELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHEEELRKEKVDKSAL 1305
E + K ++ K + + + E+ L + +R S+ DT++ +L K K + L
Sbjct: 2647 EMVIKLQNEKKDIETSTDRIRDEEANL-RVQKQRLESDRDTLEK-ERFDLEKTKTEMKDL 2704
Query: 1304 TENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASL 1125
+ + E Q + + +E I + L++ + +K+ LEK E + A +
Sbjct: 2705 EK-----QLESQSRQHEIQLVE--IQKEREILEQLKINLSKQKEDLEKERDCFEKEKADI 2757
Query: 1124 TDNQEGHEAEIERKLEASNLTHNDELHKEKDDKKSIMNDLDRVKAEKQVLESKVSDLETT 945
+ +E E + ++ + + E+ + + + +++ +L+ + +KQ++E + +E
Sbjct: 2758 SLREELEEQSEKEGIDKTRVRIKQEMDELEQTRLNVVKELENNELQKQIIEDERDKIE-- 2815
Query: 944 YSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTG--KDDDYN- 774
+ ELQ++ D E +R +E ++ E+ V+ L+ DIE T +D++ N
Sbjct: 2816 --QIKAELQKEAKDTE---KQRQDIENDRRNNEEMVIKLQNEKKDIETSTDRIRDEEANL 2870
Query: 773 -------EAEKQTLKKRISELEEAISILTDKAKKL---LKDINIWLSEVTELQEDLNK-- 630
E+++ TL+K +L++ + + D K+L + I L+E+ + +E L +
Sbjct: 2871 RVLKQRLESDRDTLEKERFDLKKTNTEMKDLEKQLESQNRQHEIQLAEIQKEREILEQLK 2930
Query: 629 --ESKEKQDLEK 600
SK+K+DLEK
Sbjct: 2931 LTLSKQKEDLEK 2942
Score = 85.9 bits (211), Expect = 1e-13
Identities = 115/526 (21%), Positives = 234/526 (44%), Gaps = 34/526 (6%)
Frame = -3
Query: 2042 IATLNDELLNEKDDKKCIV----NDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDD 1875
+A L+ EL KD+ + I +R+ +E + L ++ +E + D+ ++
Sbjct: 9124 MADLSRELQKAKDELEKIAYKTNKERHEVEQMQAELHSQIQAIEQQGQIMQDKQNHLEEK 9183
Query: 1874 NNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVN---- 1707
+I +K + +I + + Q +QE N L I N + N
Sbjct: 9184 ELSIQRKEEEIKIGNTEF---QIEQEHLNNVLEETNKRQHDLEVMRADIELNKQKNNKDF 9240
Query: 1706 --ILILHEELQKEKDD--------KTALIKDLVAAEPGKRTVNEIVSHLESK-SRSLKEH 1560
+ + EL+ EK D K + L E K + ++ L+SK ++ KE
Sbjct: 9241 ELLEKIRSELENEKYDLQIWTEQQKHLVEVQLQELEKEKERLEKMEIELQSKREQTEKEK 9300
Query: 1559 FLREEEDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLE--KTVLE 1386
+ ++R + + + + + + K+ L E E + E++ LE K +++
Sbjct: 9301 ADLNRVNAEIQREKQVIDKKRHMTNRAMEELETIKTELKERQEKIQTEQEKLEEEKLLVQ 9360
Query: 1385 RRASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDA-- 1212
A NL+ + + + K ++ ++ L E CE ++ E+ D+E I + +A
Sbjct: 9361 IEAENLNKVLEEIKRQQEKLEISEADLKVMKEQCENAREETERKKCDIEEQIQNNENAKH 9420
Query: 1211 -LQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEI--ERKL--EASN--LTHND 1053
L+++ + +KQ L+K+ DL+ + + +N E + + E+KL + +N L D
Sbjct: 9421 LLEQERKDIDKQKQELQKQADDLDMRMIAHRENVEMSKRSLDEEKKLLEQKANEILRQRD 9480
Query: 1052 ELHKEKDDKKSIMNDLDRVKAEKQVLESKVSDLETTYSTLNNEL---QQKMDDNEAFLNE 882
+L KEK+D N LD ++ E Q + +++ NE+ QQ+++++ +NE
Sbjct: 9481 DLEKEKEDMMKKWNKLDVLQNEMQNENKAMEEIKYELDGKRNEINKEQQRLEESLRAINE 9540
Query: 881 RDG-LEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTD 705
G LE ++ EK+ +E + +M E++ L + SELE+ + +
Sbjct: 9541 EKGDLEIMRADYEKQEQQIEEMRVEAKM-----------ERKELDQIKSELEKDKTEIDY 9589
Query: 704 KAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLELTSKLEK 567
+ KKL D N+ E +L++ ++ ++Q +E EL K+++
Sbjct: 9590 EWKKLNNDRNMIEKERNDLEKMKSELMTQRQQMEDERSELDQKIKE 9635
Score = 85.5 bits (210), Expect = 2e-13
Identities = 111/536 (20%), Positives = 235/536 (43%), Gaps = 46/536 (8%)
Frame = -3
Query: 2072 ESKVSVFEAAIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDEL 1893
E+K ++ E +E+ EK+ ++ R +E ++ +E + LE ++ ++ E
Sbjct: 11493 ETKANILEMKTKAEPEEIKKEKEKEEEEQEMRVKVEMERKEIEQIKSQLERVRSEMDHEQ 11552
Query: 1892 ERKKDDNNAII--KKALDKRISDLKADAPQRDQE-DDMNALIXXXXXXXXXXXXXXKIVS 1722
++ DD I K+ L+K S++ Q ++E +++ I +IV
Sbjct: 11553 KKLNDDKKMIEQEKEDLEKMKSEIMKQRQQMEEERSELDKKIKQTDLEKHDIENSKEIVE 11612
Query: 1721 NLEVNILILHEELQKEK-----------DDKTALIKDLVAAEPGKRTVNEIVSHLESKSR 1575
L V + E+Q +K D++ LI++ + + + E+ ++ +
Sbjct: 11613 KLMVEVEKQKHEIQFQKEELDIERQKIADEQDLLIQNKIEQQNENERIKEMDEEIKKERE 11672
Query: 1574 SLKEHFL-----REEEDEVLE---RSASNLAIMKAIREEELRKEKDGKSALVENGEGCEA 1419
+LKE + +EE + V+E R +L M E+ + + + L + E
Sbjct: 11673 TLKEMEVNLQKEKEEIESVIEETQRRKEDLEKMSTDINEQKQDLMNQRDLLKQ-----ER 11727
Query: 1418 EKQGLEKTVLERRASNLDTMDAI-----------HEEELRKEKVDKSALTENGEGCEAEK 1272
E+ + T L++R +T I +E+L++ + ++ E E
Sbjct: 11728 EEMNHKLTQLQQRIDEFETTSNILVTTKMEEKTEMDEKLQQAIKEYESIIEETNRKRTEL 11787
Query: 1271 QGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEI 1092
+ E + ++ D L+++ E++ L+K+ DLE + D +E + +
Sbjct: 11788 EEIEVDQSQQNKNVETMKDLLEKERKDTEKEREELQKQADDLEMQMIEHGDKEEMSKRSL 11847
Query: 1091 --ERKL--EASN--LTHNDELHKEKDDKKSIMNDLDRVKAEKQVLESKVSDLETTYSTLN 930
E+KL + +N L D+L KEK+D N+LD ++ E Q ++++ +++ T
Sbjct: 11848 DEEKKLLEQKANEILRQRDDLEKEKEDMMKKWNELDGLQKEIQNQKNEMEEIKCELETKR 11907
Query: 929 NELQQKMDDNEAFLN----ERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKD-DDYNEAE 765
E+ ++ E LN ER LE V+ EK + I ++ +KT + D+ ++
Sbjct: 11908 IEIIKEQKRLEESLNTVNEERQYLEIVRVDYEKH----QQQIEEMRVKTKMERDELDQLM 11963
Query: 764 KQTL--KKRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLE 603
+ L +K ++ I +L + ++ +++ ++ EL+ + K EK+DLE
Sbjct: 11964 AKMLMDRKENERSKDMIGLLKKEMEQTKFNLD---AQEEELKLEKQKIQNEKKDLE 12016
Score = 84.7 bits (208), Expect = 3e-13
Identities = 119/558 (21%), Positives = 246/558 (44%), Gaps = 48/558 (8%)
Frame = -3
Query: 2075 LESKVSVFEAAIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDE 1896
L+ + S + +ND + K+++K + D+ E KQ +E + D + ++ +L+++
Sbjct: 4461 LDLRQSELDKQQTNVNDIMETMKNERKQLDKDKEETEEQKQEMEKEKHDFDQSRKSLDED 4520
Query: 1895 LERKKDDNNAII--KKALDKRISDLKADAPQ--RDQEDDMNALIXXXXXXXXXXXXXXKI 1728
L+ K + K L++ +L+ +A + + +E+ N +
Sbjct: 4521 LKMMKLQKQVLEDEKSKLEQMKIELEREAVEIRKIKEEIQNERQNLEKMTEALKEEREDL 4580
Query: 1727 VSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLK--EHFL 1554
+ N +L E + ++++ E + +++ +E+K +L+ E L
Sbjct: 4581 AEETKKNNQVLDEMKVANESTLADILREKSNLEEMRENISKQTEDVENKKENLRLREDEL 4640
Query: 1553 REEEDEV------LERSASNL-----AIMKAIREEELR---KEKDGKSALVENGEGCEAE 1416
R+ + E+ +E+ N+ AI+K + + + + ++D +S ++ E E E
Sbjct: 4641 RQLQAEIHKQQREIEKEKINIESERAAIIKDVEDLQHKIICLDRDAESLKLDR-EAFENE 4699
Query: 1415 KQGLE--KTVLERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCEA----EKQGPEKT 1254
K+ L+ KT LER A ++ + E + +++V++ A + E E+ +
Sbjct: 4700 KEVLKQMKTELEREADEIEKIKL--ETQHDRQRVEEMAAQIQKDRDEINNLIEETNRKDM 4757
Query: 1253 VL-----DLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIE 1089
VL D+E I S+ Q D D + EK LEK S+L L +E AEI+
Sbjct: 4758 VLNEKNRDIEEKIKSI----QSDKDMLEKEKHDLEKTRSELYKVKEDLEKQKENTLAEIQ 4813
Query: 1088 RKLEA-----SNLT-------HNDELHKEKDD-----KKSIMNDLDRVKAEKQVLESKVS 960
++ E N+T H +E +K D K I N ++ EK+++ S
Sbjct: 4814 KEREDLEKMNENITREMHEIKHQEEQMNQKQDELDQLKTEIQNLQQELEKEKEIIMKDRS 4873
Query: 959 DLETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDD 780
L+ S L+ + D E NER L+ K+ +E++ ++E +++ D+
Sbjct: 4874 QLDLRQSELDKQQTNMNDIMETMKNERKQLDKDKEEMEEQKQEMEKERDNMDQSRKSLDE 4933
Query: 779 YNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEK 600
+ +K L+K++ E E+ +K +++ ++ E+++++E+ ++Q LEK
Sbjct: 4934 --DQKKMKLQKQMFEEEK------NKLEQMKIELEREADEISKIKEE---TQNKRQRLEK 4982
Query: 599 RVLELTSKLEKCICGARD 546
EL + E A D
Sbjct: 4983 MTEELIREKESLAHLAED 5000
Score = 83.6 bits (205), Expect = 7e-13
Identities = 118/530 (22%), Positives = 224/530 (42%), Gaps = 45/530 (8%)
Frame = -3
Query: 2072 ESKVSVFEAAIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDEL 1893
+ ++ + I L EL EK+ I+ DR+ L+ K ++L+ +T +ND +
Sbjct: 3750 QDELDQLKTEIQNLQQELEKEKE---IIMKDRS-------ELDLKQSELDKQQTNMNDII 3799
Query: 1892 ERKKDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLE 1713
E K++ + K + + + + D + N+L + +
Sbjct: 3800 ETMKNERKQLDKDKEEMEEQKREIEKEKHDFDQGRNSL-------------------DED 3840
Query: 1712 VNILILHEELQKEKDDKTALIKDLVAAEPGK-RTVNEIVSHLESKSRSLKEHFLREEED- 1539
+ ++ L +++ +E+ +K +K + E G+ R + E + + + E RE+E
Sbjct: 3841 LKMMKLQKQVFEEEKNKLEQMKIELEREAGEIRKIKEEIQNERQSLEKMTEELKREKESF 3900
Query: 1538 ----EVLERSASNLAIMKAIREE---ELRKEKDGKSALVENGEGCEAEKQGLEKTVLERR 1380
E ++ L +K E EL+KEK + EN + E +K L R
Sbjct: 3901 THLAEDTKKEQEILDEIKVANESLMAELQKEKSNFEEMRENISK-QTEDVKNKKENLRLR 3959
Query: 1379 ASNLDTMDA-IHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLN---DA 1212
L + A IH+++ EK +KS + E+E+ K V DL+ I SL+ ++
Sbjct: 3960 EDELGQLQAEIHKQQREIEK-EKSNI-------ESERAAIIKIVEDLQHKIISLDRDAES 4011
Query: 1211 LQRDLDRVMAEKQALEKRCSDLEAKNASL------TDNQEGHEAEI----------ERKL 1080
L+ D + E++ L++ ++LE + + T ++ E+ ERK
Sbjct: 4012 LKLDREAFENEREVLKQMKTELERETDEIEKIKLETQHERQRVEEMTADFMETMNNERKQ 4071
Query: 1079 EASNLTH----NDELHKEKDD----KKSIMNDLDRVKAEKQVLESKVSDLETTYSTLNNE 924
N E+ KE+ D +KS+ +L +K +KQV+E + + LE L E
Sbjct: 4072 LNKNKEEMQEQKQEMEKERHDMDQSRKSLDKNLKMMKLQKQVIEEEKNKLEQMKIELEKE 4131
Query: 923 LQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDI--------EMKTGKDDDYNEA 768
+ E NER LE + + L+K D +MK + +
Sbjct: 4132 ADEIRKIKEETQNERQRLEKMTEELKKEKESFTHLAEDTKTEKKILDKMKVANESLMADL 4191
Query: 767 EKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKE 618
+K+ K + E+ E IS T+ ++K + I + E+ +LQ +++K+ E
Sbjct: 4192 QKE--KSNLEEMRENISKQTEDSEKEKEKIRLREDELEQLQAEIHKQQGE 4239
Score = 83.6 bits (205), Expect = 7e-13
Identities = 126/569 (22%), Positives = 237/569 (41%), Gaps = 71/569 (12%)
Frame = -3
Query: 2081 QALESKVSVFEAAIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLN 1902
Q LE + S E L E + + K+ I N+R LE +AL+ + DL N
Sbjct: 4529 QVLEDEKSKLEQMKIELEREAVEIRKIKEEIQNERQNLEKMTEALKEEREDLAEETKKNN 4588
Query: 1901 DELERKKDDNNAIIKKALDKR---------ISDLKADAPQRDQ-----EDDMNALIXXXX 1764
L+ K N + + L ++ IS D + + ED++ L
Sbjct: 4589 QVLDEMKVANESTLADILREKSNLEEMRENISKQTEDVENKKENLRLREDELRQLQAEIH 4648
Query: 1763 XXXXXXXXXXKIVSNLEVNILILHEELQKE----KDDKTALIKDLVAAEPGKRTVNEIVS 1596
+ + I+ E+LQ + D +L D A E K + ++ +
Sbjct: 4649 KQQREIEKEKINIESERAAIIKDVEDLQHKIICLDRDAESLKLDREAFENEKEVLKQMKT 4708
Query: 1595 HLESKSRSLKEHFLREEEDEVL----------ERSASNLAIMKAIREEELRKEKDGK--- 1455
LE ++ +++ L + D +R N I + R++ + EK+
Sbjct: 4709 ELEREADEIEKIKLETQHDRQRVEEMAAQIQKDRDEINNLIEETNRKDMVLNEKNRDIEE 4768
Query: 1454 --SALVENGEGCEAEKQGLEKTV---------LERRASNLDTMDAIHEEELRKEKVDKSA 1308
++ + + E EK LEKT LE++ N T+ I +E EK++++
Sbjct: 4769 KIKSIQSDKDMLEKEKHDLEKTRSELYKVKEDLEKQKEN--TLAEIQKEREDLEKMNENI 4826
Query: 1307 LTENGEGCEAEKQGPEKT--VLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKN 1134
E E E+Q +K + L+ I +L L+++ + +M ++ L+ R S+L+ +
Sbjct: 4827 TREMHEIKHQEEQMNQKQDELDQLKTEIQNLQQELEKEKEIIMKDRSQLDLRQSELDKQQ 4886
Query: 1133 ASLTDNQEGHEAEIER--KLEASNLTHNDELHKEKDD----KKSIMNDLDRVKAEKQVLE 972
++ D E + E ++ K + E+ KE+D+ +KS+ D ++K +KQ+ E
Sbjct: 4887 TNMNDIMETMKNERKQLDKDKEEMEEQKQEMEKERDNMDQSRKSLDEDQKKMKLQKQMFE 4946
Query: 971 SKVSDLETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGL----------------EKR 840
+ + LE L E + E N+R LE + + L EK+
Sbjct: 4947 EEKNKLEQMKIELEREADEISKIKEETQNKRQRLEKMTEELIREKESLAHLAEDTKTEKK 5006
Query: 839 VLDLEATIHDIEMKTGKDDDYNEAEK-----QTLKKRISELEEAISILTDKAKKLLKDIN 675
+LD EMK + + ++ + +++ IS+L+E I +K K L++
Sbjct: 5007 ILD--------EMKVANESSMADLQREKSILEEMRENISKLKEYID--NEKEKSKLRE-- 5054
Query: 674 IWLSEVTELQEDLNKESKEKQDLEKRVLE 588
E+ +LQ ++ K+ + K D+EK +E
Sbjct: 5055 ---DELKKLQTEVQKQ-QSKIDMEKTNIE 5079
Score = 80.9 bits (198), Expect = 4e-12
Identities = 119/523 (22%), Positives = 221/523 (42%), Gaps = 20/523 (3%)
Frame = -3
Query: 2075 LESKVSVFEAAIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDE 1896
L++ S E + +L E N +D+K + R+ + + A+ + DLE + E
Sbjct: 8800 LQNMKSNLERQLESLRHEKANVEDEKNALEKMRSESKEIQNAIRKEREDLENCWVEIEGE 8859
Query: 1895 LERKKDDNNAI------IKKALDKRISDLKADAPQRDQE--DDMNALIXXXXXXXXXXXX 1740
+R +++ + IKK +D + + + R+++ + M L+
Sbjct: 8860 KKRMEEETRRLEMHREEIKK-VDSELQKSRENIESREEKINNKMEELLQMKVEMGRTKEE 8918
Query: 1739 XXKIVSNLEVNILILHE---ELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSL 1569
K L+ + L E+Q++ +DK I D+ E + EI L+ +++ L
Sbjct: 8919 IEKESQRLQDATIDLENAKAEIQRQ-EDKFEDIIDIKIQEKER----EIKIQLDKETKRL 8973
Query: 1568 KEHFLREEEDEVLE-----RSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGL 1404
E + +D +E R + K + E+E ++ K K L + EKQ
Sbjct: 8974 SEEIELKVKDLEMEMADMKRQKQEIEDTKGLLEKEKQELKQEKKELEDQMMDLTREKQET 9033
Query: 1403 EKTVLERRASNLDTMDAIHEEELRKEKV--DKSALTENGEGCEAEKQGPEKTVLDLEPTI 1230
E+ A D E E+ KEK+ +KS + E +++ ++T + +
Sbjct: 9034 EEERNNLMALKNQLEDLRKENEIVKEKLTLEKSNIEEMQLKIFKQQRLNDQTREENKKE- 9092
Query: 1229 PSLNDALQRDLDRVMAEKQALEKRCSDL-EAKNASLTDNQEGHEAEIERKLEASNLTHND 1053
++L++ +KQ LE + + E KN ++E +A+ E LE N
Sbjct: 9093 ---KESLEQQRFETEQQKQMLEISTTKMMEEKNEMADLSRELQKAKDE--LEKIAYKTNK 9147
Query: 1052 ELHKEKDDKKSIMNDLDRVKAEKQVLESKVSDLETTYSTLNNELQQKMDDNEAFLNERDG 873
E H+ + + + + + ++ + Q+++ K + LE ++ + ++ N F E++
Sbjct: 9148 ERHEVEQMQAELHSQIQAIEQQGQIMQDKQNHLEEKELSIQRKEEEIKIGNTEFQIEQEH 9207
Query: 872 LEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKK 693
L V + KR DLE DIE+ K N + + L+K SELE
Sbjct: 9208 LNNVLEETNKRQHDLEVMRADIELNKQK----NNKDFELLEKIRSELENE---------- 9253
Query: 692 LLKDINIWLSEVTELQE-DLNKESKEKQDLEKRVLELTSKLEK 567
D+ IW + L E L + KEK+ LEK +EL SK E+
Sbjct: 9254 -KYDLQIWTEQQKHLVEVQLQELEKEKERLEKMEIELQSKREQ 9295
Score = 80.1 bits (196), Expect = 7e-12
Identities = 122/570 (21%), Positives = 236/570 (41%), Gaps = 68/570 (11%)
Frame = -3
Query: 2075 LESKVSVFEAAIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLE--AAKTTLN 1902
+E+K + L D+ + K+D+ D LE ++ L + DLE +
Sbjct: 8616 METKKRSLDRMSRELQDDKIRLKNDRDAYEKDMTHLELKREELVRETEDLERKILQQREQ 8675
Query: 1901 DELERKKDDNNA---------IIKK-----------------------ALDKRISDLKAD 1818
DE+ ++ +N I+KK AL + S+L+
Sbjct: 8676 DEMAKRDIENQTEALEVMKVDILKKRNEFAKEMENVHSERQKLLLLQGALQSQESELENR 8735
Query: 1817 APQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDKTALIKDLV 1638
+Q+ A + + + L EELQ+EK ++ + K+ +
Sbjct: 8736 VFMEEQKHLKQAKAETEECRKQLAEMSETVTTE-QNEYRKLIEELQREK-EQLEISKNQI 8793
Query: 1637 AAEPGKRTVNEIVSHLESKSRSLK-EHFLREEEDEVLERSAS-NLAIMKAIREEELRKEK 1464
E K+ + + S+LE + SL+ E E+E LE+ S + I AIR+E
Sbjct: 8794 EQE--KKDLQNMKSNLERQLESLRHEKANVEDEKNALEKMRSESKEIQNAIRKER----- 8846
Query: 1463 DGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHEEELRKEKVDKSALTENGEGC 1284
E+ E C E +G EK +E L+ +H EE++K + EN E
Sbjct: 8847 -------EDLENCWVEIEG-EKKRMEEETRRLE----MHREEIKKVDSELQKSRENIESR 8894
Query: 1283 EAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTD----N 1116
E + + +L ++ + + ++++ R+ LE ++++ + D
Sbjct: 8895 EEKINNKMEELLQMKVEMGRTKEEIEKESQRLQDATIDLENAKAEIQRQEDKFEDIIDIK 8954
Query: 1115 QEGHEAEIERKLEASNLTHNDELHKEKDDKKSIMNDLDRVKAE----KQVLESKVSDLET 948
+ E EI+ +L+ ++E+ + D + M D+ R K E K +LE + +L+
Sbjct: 8955 IQEKEREIKIQLDKETKRLSEEIELKVKDLEMEMADMKRQKQEIEDTKGLLEKEKQELKQ 9014
Query: 947 TYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLE---------KRVLDLE-ATIHDIEMK 798
L +++ + + ER+ L A+K LE K L LE + I ++++K
Sbjct: 9015 EKKELEDQMMDLTREKQETEEERNNLMALKNQLEDLRKENEIVKEKLTLEKSNIEEMQLK 9074
Query: 797 TGKDD-------DYNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQED 639
K + N+ EK++L+++ E E+ +L K++++ N ELQ+
Sbjct: 9075 IFKQQRLNDQTREENKKEKESLEQQRFETEQQKQMLEISTTKMMEEKNEMADLSRELQKA 9134
Query: 638 LN-------KESKEKQDLEKRVLELTSKLE 570
+ K +KE+ ++E+ EL S+++
Sbjct: 9135 KDELEKIAYKTNKERHEVEQMQAELHSQIQ 9164
Score = 79.3 bits (194), Expect = 1e-11
Identities = 93/521 (17%), Positives = 226/521 (43%), Gaps = 46/521 (8%)
Frame = -3
Query: 1991 IVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKALDKR--------- 1839
++N R++L+ ++ + +K L+ + ++ ++K+++ KK ++R
Sbjct: 11161 LMNQRDLLKQEREEINHKWTQLQQRIDEFDAQVSKQKEEDLTKQKKMEEERKSLEETKIK 11220
Query: 1838 ISDLKADAP--------QRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEEL 1683
I ++K ++++E+ M A + I S LE + E
Sbjct: 11221 IIEMKTKTEPEKIKKEKEKEEEEVMRAKVEMKKEELDQ------IKSQLERVRSEIDHEQ 11274
Query: 1682 QKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNLAI 1503
+K DDK + ++ E K + + +E + RS E+ +R+ E + S +
Sbjct: 11275 KKLNDDKKMIEQEKEDLEKMKSEIMKQRQQMEEE-RSELENKIRQTYIEKCDIENSKEIV 11333
Query: 1502 MKAIREEELRKEK----------------DGKSALVENGEGCEAEKQGLEKT--VLERRA 1377
K + E E +K + D + L++N + E + ++ V+++
Sbjct: 11334 QKLMVEVEEQKHEIQFQKEELDIERQKIADEQDLLIQNKSELQNENERIKNINEVIKKER 11393
Query: 1376 SNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDL 1197
L M+A L KEK + ++TE + + + + + + + S D L+++
Sbjct: 11394 ETLKEMEAY----LEKEKEEMKSITEETRRQKEDLEKMSTHINEQKQDLRSQRDLLEQER 11449
Query: 1196 DRVMAEKQALEKRCSDLEA-----------KNASLTDNQEGHEAEIERKLEASNLTHNDE 1050
+ + + + L++R + +A K + ++++ E LE +E
Sbjct: 11450 EEINHKWKQLQQRIDEFDAQVSKQKEEDLPKEKEMKEDRKSLEETKANILEMKTKAEPEE 11509
Query: 1049 LHKEKDDKKSIMNDLDRVKAEKQVLESKVSDLETTYSTLNNELQQKMDDNEAFLNERDGL 870
+ KEK+ ++ +V+ E++ +E S LE S +++E ++ DD + E++ L
Sbjct: 11510 IKKEKEKEEEEQEMRVKVEMERKEIEQIKSQLERVRSEMDHEQKKLNDDKKMIEQEKEDL 11569
Query: 869 EAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKL 690
E +K + K+ +E +++ K K D + + + K+ + +L + + +
Sbjct: 11570 EKMKSEIMKQRQQMEEERSELDKKI-KQTDLEKHDIENSKEIVEKLMVEVEKQKHEIQFQ 11628
Query: 689 LKDINIWLSEVTELQEDLNKESKEKQDLEKRVLELTSKLEK 567
++++I ++ + Q+ L + E+Q+ +R+ E+ +++K
Sbjct: 11629 KEELDIERQKIADEQDLLIQNKIEQQNENERIKEMDEEIKK 11669
Score = 79.0 bits (193), Expect = 2e-11
Identities = 115/572 (20%), Positives = 246/572 (43%), Gaps = 91/572 (15%)
Frame = -3
Query: 2027 DELLNEKDDKKCIVND----RNILEAAKQALEYKVADLEAAKTTLND----------ELE 1890
+EL E+ D + D +N L+ K A E +ADL+ K+ L + ++E
Sbjct: 5858 EELKKERKDVAHLAEDTKREKNSLDEMKVANESSMADLQKEKSNLEEMKENISKQTEDIE 5917
Query: 1889 RKKD------DNNAIIKKALDKRISDLKADAPQRDQE--------DDMNALIXXXXXXXX 1752
++KD D ++ + K+ S+ + + ++E +D+ + I
Sbjct: 5918 KEKDKIRLREDELEQLQAEIHKQQSETEIEKSNIERERAAIIKDVEDLQSKIISLDRDAE 5977
Query: 1751 XXXXXXKIVSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSH----LES 1584
+ N + + + EL++E D+ + K + + ++ V E+ + + +
Sbjct: 5978 SLKLDREAFENEKEELKQMKTELEREADE---IEKIKLETQHERQRVEEMTADFMETMNN 6034
Query: 1583 KSRSL-KEHFLREEEDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQG 1407
+ + L K + EE+ + +E+ ++ + +E+L+ K K L E E K G
Sbjct: 6035 ERKQLDKNKVMIEEQKQEMEKKRDDMDQSRKSLDEDLKMMKAQKQVLEEEKNKLEQMKIG 6094
Query: 1406 LE---------KTVLERRASNLDTM-DAIHEE------ELRKEKVDKSALTENGEGCEAE 1275
LE K + NL+ M +A+ EE E++++ + E A+
Sbjct: 6095 LEREADEISKIKEETQNERQNLEKMANALKEEREYLAEEIKRKNQVLDKIKVANESTLAD 6154
Query: 1274 KQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAE 1095
Q ++ + ++ I + ++ + ++ + L+K ++++ + + + + E+E
Sbjct: 6155 LQKEKRILEEMRENISKQIEDIENEKEKSKLREDELKKLQTEVQKQQSEIDMEKTNIESE 6214
Query: 1094 IERKL-EASNLTHNDELHKEKDD----KKSIMNDLDRVKAEKQVLESKVSDLETTYSTLN 930
+ E N+ EL K+ +D K I+ + + + ++ +L+ V DL+ ++
Sbjct: 6215 RAAMIREKQNMM--TELKKKSEDVEMQMKEILTEKELLHNDRNLLKKDVEDLQQKLMSIE 6272
Query: 929 NELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLE----ATIHD---IEMKTGK------ 789
+ + D EAF NE++ ++ +K L+ + ++E T H+ +E KT +
Sbjct: 6273 RDSESLKLDKEAFENEKEAMKQMKTDLQIQADEIEKIKLETHHERQRVEEKTAQIQKERE 6332
Query: 788 ----------------DDDYNE--AEKQTLKKRISELEEAISILTDKAKKLLKDINIWLS 663
D+ Y E EK+ ++ S+LE+A S + K K+I I L+
Sbjct: 6333 EINTLVEEIKKKRDIIDESYTEIRKEKEAIESDRSDLEKAKS----QTFKQNKNIEIALA 6388
Query: 662 EVTELQEDLNKESKE------KQDLEKRVLEL 585
E+ + + L K SKE K + EK+ ++L
Sbjct: 6389 EIQQKRNALEKMSKEISRDRMKLEDEKKEIQL 6420
Score = 78.6 bits (192), Expect = 2e-11
Identities = 134/578 (23%), Positives = 246/578 (42%), Gaps = 76/578 (13%)
Frame = -3
Query: 2072 ESKVSVFEAAIATLNDELLNEKDD---KKCIVNDR-NILEAAKQALEYKVADLEAAKTTL 1905
+ K+ + EA + + ++ N +++ KKC + ++ E AK LE + D++ K
Sbjct: 9377 QEKLEISEADLKVMKEQCENAREETERKKCDIEEQIQNNENAKHLLEQERKDIDKQK--- 9433
Query: 1904 NDELERKKDD----------NNAIIKKALD--KRISDLKADAPQRDQEDDMNALIXXXXX 1761
EL+++ DD N + K++LD K++ + KA+ R ++D +
Sbjct: 9434 -QELQKQADDLDMRMIAHRENVEMSKRSLDEEKKLLEQKANEILRQRDD-----LEKEKE 9487
Query: 1760 XXXXXXXXXKIVSNLEVNILILHEELQKEKDDKTALI-KDLVAAEPGKRTVNEIVSHLES 1584
++ N N EE++ E D K I K+ E R +NE LE
Sbjct: 9488 DMMKKWNKLDVLQNEMQNENKAMEEIKYELDGKRNEINKEQQRLEESLRAINEEKGDLEI 9547
Query: 1583 KSRSLKEHFLREEEDEV--------LERSASNLAIMKAIREEELRKEKDGKSALVENGEG 1428
++ + EE V L++ S L K + E +K + ++ + +
Sbjct: 9548 MRADYEKQEQQIEEMRVEAKMERKELDQIKSELEKDKTEIDYEWKKLNNDRNMIEKERND 9607
Query: 1427 CEAEKQGL--EKTVLERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKT 1254
E K L ++ +E S LD I E K+K++K+ E E+Q +
Sbjct: 9608 LEKMKSELMTQRQQMEDERSELD--QKIKEANTEKDKIEKNKEIVERLMAEVEEQRNDFK 9665
Query: 1253 VLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEG--HEAEIERKL 1080
+ E + N ++ EK L + ++L+ K+ + + +E +E E ++
Sbjct: 9666 LKKEELALERQN---------IVDEKYLLAQCETELQNKSEQIRNMEEAVKNERETLKET 9716
Query: 1079 EASNLTHNDELHKEKDDKKSIMNDLDRVK-----------AEKQVLESKVSDLETTYSTL 933
EA L ++K + KSI+ + R K +KQ L++K LE +
Sbjct: 9717 EA-------HLQRDKKEIKSIIEETSRQKEDLEKISTGMNVQKQELKNKKDTLEQEREEI 9769
Query: 932 NN---ELQQKMDDNEAFLN---ERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNE 771
N+ + QQ++D+ +A + E D K E++ L+ E IEMKT + +++E
Sbjct: 9770 NHKWTQFQQRIDEFDAQVRKQKEEDLTNQKKMEEERKCLE-EVNGKIIEMKTKAELEHHE 9828
Query: 770 A-----EKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEV----TEL---------- 648
E QTL+++I + +E +T K K +D++ SE+ TE+
Sbjct: 9829 INQKIEELQTLQEQIMKEKEKAEAMTIKLKMEREDLDQIKSELVREKTEVDHEQKKLNDD 9888
Query: 647 -------QEDLNKESKE----KQDLEKRVLELTSKLEK 567
+EDL K E KQ++EK EL +K+++
Sbjct: 9889 IKMIEQEKEDLEKMKSEIMTQKQEMEKERSELDNKIQQ 9926
Score = 77.0 bits (188), Expect = 6e-11
Identities = 108/541 (19%), Positives = 221/541 (40%), Gaps = 58/541 (10%)
Frame = -3
Query: 2042 IATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAI 1863
IA + D+LL EK+D +E K+ + + +E ++ LND+ E +N +
Sbjct: 12812 IADMKDQLLKEKED----------VETTKERINREKEHIEKMQSQLNDQKEEMDLENQKL 12861
Query: 1862 I---------KKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEV 1710
+ AL+K + DL+ + +++NAL+ E
Sbjct: 12862 LYMKTEIQVKTNALEKMMQDLQKE------RENVNALVIQHQ-------------KEREQ 12902
Query: 1709 NILILHEELQKEKDDKTALIKDLVAAEPGK-------RTVNEIVSHLESKSRSLKEHFLR 1551
+++ E +KEK + + + E K ++++ S L+++S L E+ ++
Sbjct: 12903 RDILIEENKRKEKHAEAEIQRQFEDIESVKVRLVTESNQIDKMNSELKTRSEEL-ENLIK 12961
Query: 1550 EEEDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASN 1371
+++ E + KA+ E++ E + KS ++N + EK + + L++ +
Sbjct: 12962 KQQKEFETKENEMQRERKAL--EKMNAELERKSTELKN----KIEKVTVWEADLQKEKNK 13015
Query: 1370 LDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDR 1191
+ + I E E + +K+ + + E ++ + + +LE L D + L R
Sbjct: 13016 TEELKNILEREKSELYQEKAQVQQQKHEMETIRKTMKSEMENLECLRNELEDEKKSMLSR 13075
Query: 1190 VMAEKQALEKRCSDLEAKNAS----------LTDNQEGHEAEIERKLEASNLTHNDELHK 1041
+ EK ++K ++++++ S L D E +++ +E N+ + +
Sbjct: 13076 LSMEKHEIDKLKTEIQSEKESIEEEKKTLKQLKDENESKRTQLDNTIEKMNMDKLS-IQR 13134
Query: 1040 EKDDKKSIMNDLDRVKAEK-----------------------------QVLESKVSDLET 948
EKD + I DL R KAEK + L S +D+E
Sbjct: 13135 EKDSLEEIKADLQR-KAEKLDEEMRKAVQITSQISQDAKILDDDREKEEELRSMRADIER 13193
Query: 947 TYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEA 768
L +++Q L+ K+ LEK + + D+E K N+
Sbjct: 13194 QAKILESDVQL--------------LQTEKEILEKSKTENDLLREDLE----KQRKRNDL 13235
Query: 767 EKQTLKKRISELEEAISILT---DKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKR 597
Q L+K LE+ I+ +T D L ++++ E+ + +L+++ KE DL +
Sbjct: 13236 TLQELRKEKMALEQMITDITKEKDAVASLQNEVSLKQHELKNKETELDEQRKEMDDLRMQ 13295
Query: 596 V 594
+
Sbjct: 13296 L 13296
Score = 75.5 bits (184), Expect = 2e-10
Identities = 117/561 (20%), Positives = 241/561 (42%), Gaps = 56/561 (9%)
Frame = -3
Query: 2081 QALESKVSVFEAAIATLNDELLNEK----DDKKCIVNDRNILEAAKQALEYKVADLEAAK 1914
Q + ++ + IA D L+ K ++ + I N +++ ++ L+ A LE K
Sbjct: 9956 QLQKEELDIERQKIADEQDLLIQNKSELQNENERIRNINEVIKKERETLKEMEAHLEKEK 10015
Query: 1913 T---TLNDELERKKDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXX 1743
++ +E R+K+D L+K +D+K ++ D+ L
Sbjct: 10016 EEMKSITEETRRQKED--------LEKMSTDIKEQNQDLMKQRDL--LEQEKEDINHEWT 10065
Query: 1742 XXXKIVSNLEVNILILHEE---LQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRS 1572
+ + + + EE QKE ++ +++ A +T E+ + K +
Sbjct: 10066 QLQQRIDEFDAQVSKQKEEDLTKQKEMKEERKSLEETKARIIEMKTKAELEDIKKEKEKE 10125
Query: 1571 LKEHFLR---EEEDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLE 1401
+E +R E + + L+R S L ++ + E +K D K + E EKQ LE
Sbjct: 10126 EEEEEMRVKVEMDGKELDRIKSELKRERSEIDHEQKKLNDDKKII-------EQEKQNLE 10178
Query: 1400 KTVLERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPT---I 1230
K ++ + + EE E K E + E K+ +K ++++E I
Sbjct: 10179 KM----KSEIMKQRQQMEEERSELENKIKQTYIEKCD-IENSKEIVQKLMVEVEEQKHEI 10233
Query: 1229 PSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQE--GHEAEIERKLEASNLTHN 1056
+ L + ++ E+ L + S+L+ +N + + E E E +++EA
Sbjct: 10234 QFQKEELDIERQKIADEQDLLIQNKSELQNENERIRNLNEIIKKERETLKEMEA------ 10287
Query: 1055 DELHKEKDDKKSIMNDLDRVKAEKQVLESKVSD-----------LETTYSTLNN---ELQ 918
L K+K++ KS+ + R+K + + + + V+ LE +N+ +LQ
Sbjct: 10288 -HLEKKKEEIKSVSEETRRLKEDLEKMSTDVNKQNKDLMNQRDLLEQEREEINHKWKQLQ 10346
Query: 917 QKMDDNEAFLNERDGLEAVKQ-GLEKRVLDLEAT-IHDIEMKTGKDDDYNEAEKQTLKKR 744
Q++D+ +A ++++ + K+ G+++ LE T + IEMKT + + + EK+ +
Sbjct: 10347 QRIDEFDAQVSKQKEQDLPKEKGMKEDRKSLEETKANVIEMKTKAEPEEIKKEKEKENEE 10406
Query: 743 ISELEEAISILTDKAKKLL------------------KDINIWLSEVTELQEDLNKES-- 624
E EE I ++ + +K L K +N ++ + + +EDL K
Sbjct: 10407 EEEEEEEIRVIVETERKELYQIKSELERVRSEIDHEQKKLNDYMKMIEQEKEDLEKMKSE 10466
Query: 623 --KEKQDLEKRVLELTSKLEK 567
K++Q +E+ EL +K+++
Sbjct: 10467 IMKQRQQMEEERSELDNKIQQ 10487
Score = 75.1 bits (183), Expect = 2e-10
Identities = 111/513 (21%), Positives = 212/513 (41%), Gaps = 67/513 (13%)
Frame = -3
Query: 1904 NDELERKKDD-NNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKI 1728
ND +E+ ++D NNA+ K +D+ D++ QE A++ I
Sbjct: 1457 NDRVEQMREDVNNAL--KDIDQAKEDIQRQREVIAQEKVQPAIVATKSSEYAKTEEPGAI 1514
Query: 1727 VSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLRE 1548
S + L L +QKE+ + K+++ E K +N+I +++ +E ++
Sbjct: 1515 KS-YRASDLELSASIQKERQELEHY-KEIILKE--KHELNKIKEDVKAVKNDAEERMIKL 1570
Query: 1547 EEDEVLERSASNLAIMKAIREEELRKEKD--GKSALVENGEGCEAEKQGL---------E 1401
E+E E +++ R+ + KEK+ G A+ + KQ L E
Sbjct: 1571 HEEEK-EMKTKRVSLQNWERQLQTEKEKNQKGLDAIWNENQQLNERKQQLDIKELHLQSE 1629
Query: 1400 KTVLERR-------------------ASNLDTMDAIHEEELRKEKVDKSALTENGEGCEA 1278
K+ LE + AS D +I E + +++ ++ + C
Sbjct: 1630 KSKLEYKKPLEIKQVDAQVQTELMEDASEYDMALSIEELDKQRQFLEYFKQELLAQKCTM 1689
Query: 1277 EKQGPE-------------------KTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRC 1155
E+Q E +T D+E + L++ D + K ++K
Sbjct: 1690 ERQMAEIELSRDELSLREATLQTATQTTADMELQLELQKQELEQTKDEMERTKLEVQKGW 1749
Query: 1154 SDLEAKNASLTDNQEGHEAEIERKLEASNLTHND-ELHK---EKDDKKSIMNDLDRVKAE 987
DL+ + A + +E E+E+ + N D E K E D K ++ + + ++A+
Sbjct: 1750 VDLQTQIAESREKEEMVRIELEKARDVLNRIRQDVETEKQTMEADLKFTLAKEFENLEAQ 1809
Query: 986 KQVLESKVSDLETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDI 807
++++E + LE L E +ER +E + L++ +LE HD+
Sbjct: 1810 RKMMEDEKRALENMKYELQRESGYIERSKHNMHDERQNMENWAEKLKQEWEELEKKRHDM 1869
Query: 806 EM------KTGKD-DDYNEAEKQTLK--KRISELEEAISILTDKAKKLLKD----INIWL 666
+ + KD ++ E + TL K S++ E IS L + K +++ I I
Sbjct: 1870 QQLQTERSREIKDLENLRELNELTLNQIKTKSDVLEKISELNSQQKDEIENEKSKIKIRE 1929
Query: 665 SEVTELQEDLNKESKEKQDLEKRVLELTSKLEK 567
++ ++Q DLN++ KE QD++ V S+L+K
Sbjct: 1930 YDLQQMQTDLNRQQKEMQDIQNAVFMEKSELKK 1962
Score = 73.6 bits (179), Expect = 7e-10
Identities = 118/540 (21%), Positives = 235/540 (43%), Gaps = 37/540 (6%)
Frame = -3
Query: 2075 LESKVSVFEAAIATLN-DELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLND 1899
LE + FE A ++ E L E+ +K+ I D+ + ++ E + L K N+
Sbjct: 2743 LEKERDCFEKEKADISLREELEEQSEKEGI--DKTRVRIKQEMDELEQTRLNVVKELENN 2800
Query: 1898 ELERK--KDDNNAI--IKKALDKRISDLKADAPQRDQEDDMN---ALIXXXXXXXXXXXX 1740
EL+++ +D+ + I IK L K D + ++D E+D ++
Sbjct: 2801 ELQKQIIEDERDKIEQIKAELQKEAKD--TEKQRQDIENDRRNNEEMVIKLQNEKKDIET 2858
Query: 1739 XXKIVSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEH 1560
+ + E N+ +L + L+ ++D L K+ + + ++ LES++R +
Sbjct: 2859 STDRIRDEEANLRVLKQRLESDRD---TLEKERFDLKKTNTEMKDLEKQLESQNRQHEIQ 2915
Query: 1559 FLR-EEEDEVLERSASNLAIMKAIREEE---LRKEKDGKSALVENGEGCEAEKQGLEKTV 1392
++E E+LE+ L+ K E+E KEK S E E ++E++G+ KT
Sbjct: 2916 LAEIQKEREILEQLKLTLSKQKEDLEKERDCFEKEKADISLREELQE--QSEREGIGKT- 2972
Query: 1391 LERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDA 1212
R MD EL++ +++ EN E +KQ
Sbjct: 2973 ---RVRIKKEMD-----ELKQTRLNVVKELENNE---LQKQ------------------I 3003
Query: 1211 LQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASNLTHNDELHKEKD 1032
++ + D++ K L+K D E + + ++ +E E+ KL+ + +D
Sbjct: 3004 IEDERDKIEQIKAELQKEAEDTEKQRRDIEKDRRNNE-EMVIKLQNEKKDIETSTDRIRD 3062
Query: 1031 DKKSIMNDLDRVKAEKQVLESKVSDLETTYSTLNN---ELQQKMDDNEAFL----NERDG 873
++ ++ R+++++ LE + DLE T + + N +L+ ++ +E L ER+
Sbjct: 3063 EEANLEVQKQRLESDRDTLEKERFDLEKTKTEMGNLKKQLESQIRQHEIQLVEIQKEREI 3122
Query: 872 LEAVKQGLEKRVLDLEATIHDIEMKTG----KDDDYNEAEKQ-------TLKKRISELEE 726
LE +K L K+ DLE E + +D ++E++ +K+ + ELE+
Sbjct: 3123 LEQLKINLSKQKEDLEKERDCFEKEKADISLSEDLKEQSEREGIDNTRTRIKQEMDELEK 3182
Query: 725 AISIL------TDKAKKLLKDINIWLSEV-TELQEDLNKESKEKQDLEKRVLELTSKLEK 567
L + KK+++D + ++ EL+++ K E Q+ + + E +KL+K
Sbjct: 3183 TRQNLAKEQENNELQKKIIEDERDKIEQIKAELKKEAEKTKLELQNERQNLEEAGTKLKK 3242
Score = 73.2 bits (178), Expect = 9e-10
Identities = 101/486 (20%), Positives = 210/486 (43%), Gaps = 13/486 (2%)
Frame = -3
Query: 2036 TLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIK 1857
TL + N + I N+ L + + L D+ L + E + N +++
Sbjct: 6641 TLEEMRANISKQVETITNENKSLSSRESELAKLQEDI------LQQQQEMDELKNTIMME 6694
Query: 1856 KA-LDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQ 1680
LD+R SD+ D Q++ +D M+ ++N+E L + + +
Sbjct: 6695 MCQLDQRQSDI--DLLQKEVDDLMD--------------FTKTEMANVERERLEVLAQTR 6738
Query: 1679 KEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEV-LERSASNLAI 1503
K D +L + A E + +NE +E + L ++ ++D++ ++R NL +
Sbjct: 6739 NIKSDMVSLKMEKEACEQLRLKLNEEKDLIEKERELLTKNLDHTDKDKMDMKRELENLKV 6798
Query: 1502 MKAIREEELRKEKDGKSALVENGEGCE--AEKQGLEKTVLERRASN----LDTMDAIHEE 1341
K + E ++ + K +L G + +EK E+ ++E A+ LD + E
Sbjct: 6799 EKETIKNEKKELEKMKISLQRKAIGFKEFSEKTKDERPIVEEMAAQFTRQLDISERPAEG 6858
Query: 1340 ELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEK 1161
+ +E++D++ + EKT DL+ T +N D + + ++ L K
Sbjct: 6859 KFIEERLDQTEKKRRKTYYTEDLFQEEKT--DLQKTKEEIN----YDREEIYRQRTELNK 6912
Query: 1160 RCSDLEAKNASLTDNQEGHEAEIERKLEASNLTHNDELHKEKDDKKSIMNDLDRVKAEKQ 981
E E +++ SNL + + KEK+ + N+LD+++AE
Sbjct: 6913 -------------------EKETLKQMHTSNLKEIENIEKEKEKIQRTWNELDQIRAE-- 6951
Query: 980 VLESKVSDLETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEM 801
L++K D++ T + + E + D E NE+D L+ ++ ++K + +L+ E
Sbjct: 6952 -LQNKQRDMDDTTNIMMKEKAELARDLENLQNEKDELQKSRENIQKLMKELQ------EE 7004
Query: 800 KTGKDDDYNEAEKQ---TLKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQ--EDL 636
+ + N+ +Q +K + L+E + + + + L+ D I ++ +LQ +D+
Sbjct: 7005 RLKTSEALNKERQQFTEEIKLKNDSLDEIQAEIDRQKRALVTDKEIITKQMMDLQKTQDV 7064
Query: 635 NKESKE 618
++S E
Sbjct: 7065 RRQSDE 7070
Score = 72.8 bits (177), Expect = 1e-09
Identities = 109/496 (21%), Positives = 222/496 (44%), Gaps = 26/496 (5%)
Frame = -3
Query: 1994 CIVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAI-IKKALDKRISDLKAD 1818
C+ D L+ ++A E + L+ KT ELER+ D+ I ++ D++ + A
Sbjct: 4681 CLDRDAESLKLDREAFENEKEVLKQMKT----ELEREADEIEKIKLETQHDRQRVEEMAA 4736
Query: 1817 APQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDKTALIKDLV 1638
Q+D+ D++N LI L + E+++ + DK L K+
Sbjct: 4737 QIQKDR-DEINNLIEETNRKDMV----------LNEKNRDIEEKIKSIQSDKDMLEKEKH 4785
Query: 1637 AAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNLAI-MKAIR--EEELRKE 1467
E + + ++ LE + + +E ED LE+ N+ M I+ EE++ ++
Sbjct: 4786 DLEKTRSELYKVKEDLEKQKENTLAEIQKERED--LEKMNENITREMHEIKHQEEQMNQK 4843
Query: 1466 KDG----KSALVENGEGCEAEKQGL--EKTVLERRASNLDTMDAIHEEELRKEKVDKSAL 1305
+D K+ + + E EK+ + +++ L+ R S LD + + K ++ L
Sbjct: 4844 QDELDQLKTEIQNLQQELEKEKEIIMKDRSQLDLRQSELDKQQTNMNDIMETMKNERKQL 4903
Query: 1304 TENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASL 1125
++ E E +KQ EK +++ + SL++ D ++ +KQ E+ + LE L
Sbjct: 4904 DKDKEEMEEQKQEMEKERDNMDQSRKSLDE----DQKKMKLQKQMFEEEKNKLEQMKIEL 4959
Query: 1124 TDNQEGHEAEIERKLEASNLTHNDELHKEKDD----KKSIMNDLDRVKAEKQVL------ 975
EA+ K++ L K ++ K+S+ + + K EK++L
Sbjct: 4960 E-----READEISKIKEETQNKRQRLEKMTEELIREKESLAHLAEDTKTEKKILDEMKVA 5014
Query: 974 -ESKVSDLETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMK 798
ES ++DL+ S L ++M +N + L E E K L E + ++ +
Sbjct: 5015 NESSMADLQREKSIL-----EEMRENISKLKEYIDNEKEKSKLR------EDELKKLQTE 5063
Query: 797 TGKDDDYNEAEKQTLK-KRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESK 621
K + EK ++ +R + + E +++T+ KK +D+ I + E+ +E L+ + K
Sbjct: 5064 VQKQQSKIDMEKTNIESERAAMIREKQNMMTE-LKKKSEDVEIQMKEILTEKELLHNDRK 5122
Query: 620 ----EKQDLEKRVLEL 585
+ ++L++++++L
Sbjct: 5123 LLTRDVENLQQKLIDL 5138
Score = 72.4 bits (176), Expect = 2e-09
Identities = 119/603 (19%), Positives = 247/603 (40%), Gaps = 64/603 (10%)
Frame = -3
Query: 2042 IATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAI 1863
+ L E+ ++ K ++++ I ++ Q L + + L E+E K D
Sbjct: 8209 VRNLKGEMERRMEESKVEIDEKEIFKSEIQRLIQDIGQIRENLGGLKTEIENTKRD---- 8264
Query: 1862 IKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEEL 1683
K L+K ++L + Q+++E L + ++E++ ++ E+
Sbjct: 8265 -KSNLEKMKAEL--EEKQQEEESMREILQKEKEELEQLKKDINREKEDIEISRELVESEI 8321
Query: 1682 -----------QKEKDDKTALIKDLVAAEPGKRTVNEIVSHLES----------KSRSLK 1566
QK K++ + ++L+ + +N V HL K ++
Sbjct: 8322 YEGEVKGFTDVQKYKEELQIVTEELLTKKRNLEQLNSDVQHLMQTLEEVDIQYIKKKAEL 8381
Query: 1565 EHFLRE--EEDEVLERSASNL--------------AIMKAIREEELRKEKDGKSALVENG 1434
EH E + +++LE+ L +++I E L+K +D + +
Sbjct: 8382 EHITSEIQKREQILEKQKKKLEENGWIIEEIEMMKVTLESINMEILQKRED----MEKEK 8437
Query: 1433 EGCEAEKQGLE--KTVLERRASNLDT--MDAIHEEELRKEKVDKSALTENGEGCEAEKQG 1266
E EKQ E + L+R+ +++ I E++ K K+D E E E +
Sbjct: 8438 ENLRREKQETELFRGELQRQRDEVESSRQALIMEKDQFKLKIDHQR-NEMSAAFEKEHKR 8496
Query: 1265 PEKTVLDLE----PTIPSLNDA------LQRDLDRVMAEKQALEKRCSDLEAKNASLTDN 1116
E DLE SLNDA LQ+ + + EK+ +E+ ++ + +
Sbjct: 8497 LENMENDLENQRAKLAESLNDAAKMEQKLQQMKNELNKEKEQVEEMKQMVKTERVKIEQE 8556
Query: 1115 QE-----------GHEAEIERKLEASNLTHNDELHKEKDDKKSIMNDLD-RVKAEKQVLE 972
+E GHE ++++K E + D+L ++ + + + DL +++ ++Q +E
Sbjct: 8557 KEEMRKQTQEIEDGHE-KLQKKTEIA-----DKLLQDANSESDRLKDLSMKLQMQRQDIE 8610
Query: 971 SKVSDLETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTG 792
+++ET +L+ ++ DD N+RD E LE + +L D+E K
Sbjct: 8611 KTNTEMETKKRSLDRMSRELQDDKIRLKNDRDAYEKDMTHLELKREELVRETEDLERKIL 8670
Query: 791 KDDDYNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQ 612
+ + +E K+ ++ + LE + K + K++ SE +L ++
Sbjct: 8671 QQREQDEMAKRDIENQTEALEVMKVDILKKRNEFAKEMENVHSERQKLLLLQGALQSQES 8730
Query: 611 DLEKRV-LELTSKLEKCICGARDGLSTIKEAWMSDCMVPDNWVPFEDLVQGFSRKTSPLD 435
+LE RV +E L++ + + E MS+ + + + L++ R+ L+
Sbjct: 8731 ELENRVFMEEQKHLKQAKAETEECRKQLAE--MSETVTTEQ-NEYRKLIEELQREKEQLE 8787
Query: 434 ITK 426
I+K
Sbjct: 8788 ISK 8790
Score = 71.6 bits (174), Expect = 3e-09
Identities = 103/494 (20%), Positives = 209/494 (42%), Gaps = 8/494 (1%)
Frame = -3
Query: 2042 IATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLND---ELERKKDDN 1872
I ++ +E +K+D + I N+ KQ L+ K LE + +N + +++ D+
Sbjct: 9727 IKSIIEETSRQKEDLEKISTGMNV---QKQELKNKKDTLEQEREEINHKWTQFQQRIDEF 9783
Query: 1871 NAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILH 1692
+A ++K ++ +++ K +R +++N I ++ + H
Sbjct: 9784 DAQVRKQKEEDLTNQKKMEEERKCLEEVNGKII-----------------EMKTKAELEH 9826
Query: 1691 EELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASN 1512
E+ ++ I++L +T+ E + + K+ ++ E ED L++ S
Sbjct: 9827 HEINQK-------IEEL-------QTLQEQIMKEKEKAEAMTIKLKMERED--LDQIKSE 9870
Query: 1511 LAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGL--EKTVLERRASNLDTMDAIHEEE 1338
L K + E +K D + + E E K + +K +E+ S LD + I + +
Sbjct: 9871 LVREKTEVDHEQKKLNDDIKMIEQEKEDLEKMKSEIMTQKQEMEKERSELD--NKIQQTD 9928
Query: 1337 LRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKR 1158
L K ++KS E E+Q E I + L + ++ E+ L +
Sbjct: 9929 LEKHDIEKSKEIVEKLMFEVEEQRHE---------IQLQKEELDIERQKIADEQDLLIQN 9979
Query: 1157 CSDLEAKNASLTDNQE--GHEAEIERKLEASNLTHNDELHKEKDDKKSIMNDLDRVKAEK 984
S+L+ +N + + E E E +++EA L KEK++ KSI + R +K
Sbjct: 9980 KSELQNENERIRNINEVIKKERETLKEMEA-------HLEKEKEEMKSITEETRR---QK 10029
Query: 983 QVLESKVSDLETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIE 804
+ LE +D++ + N+ + +RD LE K+ + L+ I + +
Sbjct: 10030 EDLEKMSTDIK--------------EQNQDLMKQRDLLEQEKEDINHEWTQLQQRIDEFD 10075
Query: 803 MKTGKDDDYNEAEKQTLKKRISELEEA-ISILTDKAKKLLKDINIWLSEVTELQEDLNKE 627
+ K + + +++ +K+ LEE I+ K K L+DI + E +E K
Sbjct: 10076 AQVSKQKEEDLTKQKEMKEERKSLEETKARIIEMKTKAELEDIKKEKEKEEEEEEMRVKV 10135
Query: 626 SKEKQDLEKRVLEL 585
+ ++L++ EL
Sbjct: 10136 EMDGKELDRIKSEL 10149
Score = 71.6 bits (174), Expect = 3e-09
Identities = 112/532 (21%), Positives = 220/532 (41%), Gaps = 62/532 (11%)
Frame = -3
Query: 1982 DRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKAL--------DKRISDL 1827
D+ ++ K +LE ADL+ L++E+ + + I + A ++ + +
Sbjct: 13128 DKLSIQREKDSLEEIKADLQRKAEKLDEEMRKAVQITSQISQDAKILDDDREKEEELRSM 13187
Query: 1826 KADAPQRDQ--EDDMNALIXXXXXXXXXXXXXXKIVSNLEV----NILILHEELQKEKDD 1665
+AD ++ + E D+ L + +LE N L L +EL+KEK
Sbjct: 13188 RADIERQAKILESDVQLLQTEKEILEKSKTENDLLREDLEKQRKRNDLTL-QELRKEKMA 13246
Query: 1664 KTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVLE--RSASNLAIMKAI 1491
+I D+ + + V+ L+++ SLK+H L+ +E E+ E + +L + +
Sbjct: 13247 LEQMITDITKEK-------DAVASLQNEV-SLKQHELKNKETELDEQRKEMDDLRMQLEM 13298
Query: 1490 REEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTM---------------D 1356
R+ K++ + + + ++ + E R D + D
Sbjct: 13299 RQNSTNKQQQEVDVFIVENMKMRNDLESMKTLLDEERRQLQDNIKTFEDQKNVLHPSKTD 13358
Query: 1355 AIHE-EELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLN---DALQRDLDRV 1188
A+ + +EL K D E+ E E K ++ + + SLN + ++++
Sbjct: 13359 AVQQTDELEKFTTDIKTEKEHVEKEREEIDVLNKEIIKSKEELQSLNLEIEMFKQEIAGK 13418
Query: 1187 MAEKQALEKRCSDLEA------------KNASLTDNQEGHEAEIERKL-----EASNLTH 1059
A+ ++LE+ +DL A K ++ D ++ E E++ L E L +
Sbjct: 13419 RAQIESLEQLRADLLAGADDIKTLVQTEKQMAIEDTEKKTEVELQMNLQKQKNELEELRN 13478
Query: 1058 NDELHKEKDDKKSIMNDLDR---------VKAEKQVLESKVSDLETTYSTLNNELQQKMD 906
E K + + + IM D + +K+E+ VLE + S+L LN ++Q++ +
Sbjct: 13479 TIEAEKHQVENRKIMLDKQQKEVEDIMTVIKSERDVLEKEKSELNKLSHVLNEKVQREQE 13538
Query: 905 DNEAFLN-ERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELE 729
+ E L ERD +E K+ +E +EKQ++++ +EL
Sbjct: 13539 ELERLLEKERDDIENCKKIIE-------------------------SEKQSIERERAEL- 13572
Query: 728 EAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLELTSKL 573
K+L +++ + E T LQ+D N KEK+ LE T ++
Sbjct: 13573 ----------KRLKEEVEVQ-HERTLLQQDKNMIQKEKEHLEGEKARTTEEI 13613
Score = 70.1 bits (170), Expect = 7e-09
Identities = 113/520 (21%), Positives = 220/520 (42%), Gaps = 45/520 (8%)
Frame = -3
Query: 2018 LNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKA---L 1848
L EK+ + + D L ++ L+ A + K + E +KD+ AI++K +
Sbjct: 12304 LQEKNVQMGTILDE--LNKRQEELDAIKAKTQREKEQMGHTEELEKDELIAILQKREEIV 12361
Query: 1847 DKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILI-LHEELQKEK 1671
+ + +++ + +E D + +++ N E + L + L+K+K
Sbjct: 12362 KRHMEEIQNQREELQKEKDQFGNMQAELQKGQLEMEMHQLMLNSERDELNGMRVNLEKQK 12421
Query: 1670 DDKTALIKDLVAAEPG---------KRTVNEIVSHLESKSRSLK----EHFLREEEDEVL 1530
++ + ++L + P K+ V E+ + L + + E R E+ + +
Sbjct: 12422 EEFELMQQNLESRRPESLLEDILKEKKRVEEMAAQLSKEQEEFRNIMSETIKRMEKIKQI 12481
Query: 1529 ERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAI 1350
E I A EE +KE D + + E CE ++ + + L + + +D
Sbjct: 12482 EGEIKTKQIEMACLEELKQKELDEQKNMRE----CENQELQMRREELAKMKTEID----- 12532
Query: 1349 HEEELRKEKVDKSALTENGEGCEAE-------KQGPEKTVLDLEPTIPSLNDALQRDLDR 1191
+ ++++ K E CE E K+ PEK +++ +D + +D
Sbjct: 12533 ----IERDEIQKLRKQYEKEKCELEQIKPDLQKREPEKIDAEVQ------HDEIHGGIDS 12582
Query: 1190 VMAEKQALEKRCSDLEAKNASLT----------DNQEGHEAEIERKLEASNLTHNDELHK 1041
+ E++ +EK +DL+ K D E EAEIE+ A ND
Sbjct: 12583 LKEEREEIEKMKADLQNKLREAENMRDIMKREKDELEKKEAEIEQM--AVETEDNDSDKN 12640
Query: 1040 EKDDKKSIMNDLDRVKAEKQVLES-------KVSDLETTYSTLNNE---LQQKMDDNEAF 891
+D+ I L K +K LE + ++LET L E L +K+ + E F
Sbjct: 12641 LQDEMMKIEAILKVTKKQKNYLEQMNENLTREKTELETNCQMLEREKTELNKKVKETEEF 12700
Query: 890 -LNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISI 714
+++ + EA ++ +E RV+D A H+ ++K +++ N E+ +KK+ LEE+++
Sbjct: 12701 HMSKMEEREAERKTIE-RVMDEMAEEHE-KIKKEREELVNMEEE--IKKQRRVLEESMNE 12756
Query: 713 LTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRV 594
+T K +ELQ + ++ K+KQ LE +
Sbjct: 12757 MTKKK--------------SELQHERSELYKQKQQLEDMI 12782
Score = 69.3 bits (168), Expect = 1e-08
Identities = 108/561 (19%), Positives = 243/561 (43%), Gaps = 50/561 (8%)
Frame = -3
Query: 2051 EAAIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDE---LERKK 1881
E+ L++E +D+ K + +N+L +K + +LE T + E +E+++
Sbjct: 13325 ESMKTLLDEERRQLQDNIKTFEDQKNVLHPSKTDAVQQTDELEKFTTDIKTEKEHVEKER 13384
Query: 1880 DD----NNAIIK-----KALDKRISDLKAD-APQRDQEDDMNALIXXXXXXXXXXXXXXK 1731
++ N IIK ++L+ I K + A +R Q + + L +
Sbjct: 13385 EEIDVLNKEIIKSKEELQSLNLEIEMFKQEIAGKRAQIESLEQLRADLLAGADDIKTLVQ 13444
Query: 1730 IVSNLEVNI------LILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSL 1569
+ + + L LQK+K++ L ++ + AE K V L+ + + +
Sbjct: 13445 TEKQMAIEDTEKKTEVELQMNLQKQKNELEEL-RNTIEAE--KHQVENRKIMLDKQQKEV 13501
Query: 1568 KEHF-LREEEDEVLERSASNLAIMKAIREEELRKEKDGKSALVENG----EGC----EAE 1416
++ + + E +VLE+ S L + + E++++E++ L+E E C E+E
Sbjct: 13502 EDIMTVIKSERDVLEKEKSELNKLSHVLNEKVQREQEELERLLEKERDDIENCKKIIESE 13561
Query: 1415 KQGLEKTVLERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEP 1236
KQ +E+ E + + ++ HE L ++ DK+ + + E E EK + + +L+
Sbjct: 13562 KQSIERERAELKRLK-EEVEVQHERTLLQQ--DKNMIQKEKEHLEGEKARTTEEIHNLKE 13618
Query: 1235 TIPSLNDALQRDLDRVMAEKQALE--------------KRCSDL---EAKNASLTDNQEG 1107
I + L + A++Q E K+ D+ E TD +
Sbjct: 13619 EIKRKSSELDMLNKEIEAKRQEEELHGLPEEIEIEDHLKKEDDVLREEIIKKQQTDASQK 13678
Query: 1106 HEAEIERKLEASNLTHNDELHKEKDDKKSIMNDLDRVKAEKQVL----ESKVSDLETTYS 939
+ + + +A T DE+ K + ++ + + A++ ++ ++ S+++
Sbjct: 13679 FQLKTTSR-DAETQTSLDEITKTDERRQRALEETVATTAKQPIVIKLEDTLTSEVQEMRD 13737
Query: 938 TLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQ 759
LNNE+++ E+D L+ K ++ ++ + E + + + +++ +
Sbjct: 13738 HLNNEIKELARMKTIMKMEKDQLKQAKSDIQTQMEEFERNMEEAMEEKSRNE-------E 13790
Query: 758 TLKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLELTS 579
L + + E+ + L K K++ + +L ++ +L+ + K+K+++E +L+L
Sbjct: 13791 KLLQLTHDKEDLSNTLDKKNKEIENNTETFLKKIAQLETTIVLMKKDKENIENELLQLKQ 13850
Query: 578 -KLEKCICGARDGLSTIKEAW 519
+ E+ I D ST KE +
Sbjct: 13851 IEQEREIQRKADVTSTEKEMY 13871
Score = 68.9 bits (167), Expect = 2e-08
Identities = 118/565 (20%), Positives = 246/565 (43%), Gaps = 87/565 (15%)
Frame = -3
Query: 2000 KKC-IVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKALD-----KR 1839
+KC I N + I++ +E + +++ K L+ E ++ D+ + +I+ + +R
Sbjct: 10208 EKCDIENSKEIVQKLMVEVEEQKHEIQFQKEELDIERQKIADEQDLLIQNKSELQNENER 10267
Query: 1838 ISDL-KADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDK 1662
I +L + +R+ +M A + + ++ L E+L+K D
Sbjct: 10268 IRNLNEIIKKERETLKEMEAHLEKKKEE----------IKSVSEETRRLKEDLEKMSTDV 10317
Query: 1661 TALIKDLVAAEPGKRTVNEIVSHL----------------ESKSRSLKEHFLREEEDEVL 1530
KDL+ E ++H + K + L + +E+ + L
Sbjct: 10318 NKQNKDLMNQRDLLEQEREEINHKWKQLQQRIDEFDAQVSKQKEQDLPKEKGMKEDRKSL 10377
Query: 1529 ERSASNLAIMKAIRE-EELRKEKDGKSALVENGEG-----CEAEKQGLE--KTVLERRAS 1374
E + +N+ MK E EE++KEK+ ++ E E E E++ L K+ LER S
Sbjct: 10378 EETKANVIEMKTKAEPEEIKKEKEKENEEEEEEEEEIRVIVETERKELYQIKSELERVRS 10437
Query: 1373 NLDT--------MDAIHEEELRKEKV-------------DKSALTENGEGCEAEKQGPEK 1257
+D M I +E+ EK+ ++S L + EK EK
Sbjct: 10438 EIDHEQKKLNDYMKMIEQEKEDLEKMKSEIMKQRQQMEEERSELDNKIQQTNLEKHDIEK 10497
Query: 1256 TVLDLEPTIPSLNDA---LQRDLDRVMAEKQALEKRCSDLEAKNASL-TDNQEGHEAEIE 1089
+ +E + + + +Q + + E+Q + + L A L +N+ + + E
Sbjct: 10498 SKEIVEKLMVEVEEQRKDIQLQKEELDIERQKIADEQNLLVQNKAKLQNENERIKKVDEE 10557
Query: 1088 RKLEASNLTHND-ELHKEKDDKKSIMNDLDRVKAEKQVLESKVSD-----------LETT 945
K E L + L KEK++ +SI+ + R K + + + + +++ LE
Sbjct: 10558 IKKERETLREMEIHLKKEKEELRSIIEETQRRKEDLEKMSTDINEQKLHLKNQRDLLEQE 10617
Query: 944 YSTLNNE---LQQKMDDNEAFLNE------RDGLEAVKQGLEK---RVLDLE--ATIHDI 807
+N+E LQQ++D+ +A +++ + +E ++ LE+ R+++++ A + +I
Sbjct: 10618 REEINHEMTQLQQRIDEFDAQVSKQREDLTKQEMEEERKSLEETKARIIEMKTKAELQEI 10677
Query: 806 EMKTGKDDDYN-----EAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQE 642
+ ++D+ E E++ L + SEL+ S + + KKL D I E +L++
Sbjct: 10678 MQEKEEEDEEEMRVIVEMEREELNQIKSELKRVRSEIDHEQKKLNDDKKIIEQEKEDLEK 10737
Query: 641 DLNKESKEKQDLEKRVLELTSKLEK 567
++ ++Q +E+ EL +K+++
Sbjct: 10738 MKSEIMTQRQQMEEERSELDNKIKQ 10762
Score = 68.2 bits (165), Expect = 3e-08
Identities = 116/566 (20%), Positives = 230/566 (40%), Gaps = 63/566 (11%)
Frame = -3
Query: 2075 LESKVSVFEAAIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDE 1896
+E ++ + +A L + E D++K N+ E Q L+ + +L KT + +
Sbjct: 12481 IEGEIKTKQIEMACLEELKQKELDEQK------NMRECENQELQMRREELAKMKTEI--D 12532
Query: 1895 LERKKDDNNAIIKKALDKRISDLKADAP--QRDQEDDMNALIXXXXXXXXXXXXXXKIVS 1722
+ER D ++K +K +L+ P Q+ + + ++A +
Sbjct: 12533 IER---DEIQKLRKQYEKEKCELEQIKPDLQKREPEKIDAEVQH---------------D 12574
Query: 1721 NLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEE 1542
+ I L EE ++ + K L L AE + + LE K +++ + E+
Sbjct: 12575 EIHGGIDSLKEEREEIEKMKADLQNKLREAENMRDIMKREKDELEKKEAEIEQMAVETED 12634
Query: 1541 DEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKT--VLERRASNL 1368
++ + + ++AI L+ K K+ L + E EK LE +LER + L
Sbjct: 12635 NDSDKNLQDEMMKIEAI----LKVTKKQKNYLEQMNENLTREKTELETNCQMLEREKTEL 12690
Query: 1367 DT---------MDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLND 1215
+ M + E E ++ +++ + E E E K+ E+ V ++E I
Sbjct: 12691 NKKVKETEEFHMSKMEEREAERKTIER-VMDEMAEEHEKIKKEREELV-NMEEEIKKQRR 12748
Query: 1214 ALQRDLDRVMAEKQALEKRCSDLEAKNASLTD---------------NQEGHEAEIERKL 1080
L+ ++ + +K L+ S+L + L D Q+ + +I ++
Sbjct: 12749 VLEESMNEMTKKKSELQHERSELYKQKQQLEDMIASESKRDVDTERSRQDKEDEQILKRE 12808
Query: 1079 EASNLTHNDELHKEKDDKKSIMNDLDRVKAEKQVLESKVSD--------------LETTY 942
D+L KEK+D ++ ++R K + ++S+++D ++T
Sbjct: 12809 REEIADMKDQLLKEKEDVETTKERINREKEHIEKMQSQLNDQKEEMDLENQKLLYMKTEI 12868
Query: 941 STLNNELQQKMDDNEAFLNERDGLEAV-----KQGLEKRVL-------------DLEATI 816
N L++ M D + ER+ + A+ K+ ++ +L +++
Sbjct: 12869 QVKTNALEKMMQDLQ---KERENVNALVIQHQKEREQRDILIEENKRKEKHAEAEIQRQF 12925
Query: 815 HDIE-MKTGKDDDYNEAEKQT--LKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQ 645
DIE +K + N+ +K LK R ELE I KK K+ ++ E+Q
Sbjct: 12926 EDIESVKVRLVTESNQIDKMNSELKTRSEELENLI-------KKQQKEFE---TKENEMQ 12975
Query: 644 EDLNKESKEKQDLEKRVLELTSKLEK 567
+ K +LE++ EL +K+EK
Sbjct: 12976 RERKALEKMNAELERKSTELKNKIEK 13001
Score = 67.8 bits (164), Expect = 4e-08
Identities = 105/526 (19%), Positives = 214/526 (40%), Gaps = 32/526 (6%)
Frame = -3
Query: 2075 LESKVSVFEAAIATLNDELLNEKDDKKC----IVNDRNILEAAKQALEYKVADL------ 1926
L+ V+ A L ++LL E++ K I ++++L KQ + + D+
Sbjct: 3289 LKKTVTDIAGAKEDLENQLLEEREKNKVKQAEIQAEKDMLYLLKQGISEQQVDIVNKTEQ 3348
Query: 1925 ----EAAKTTLNDELERKKDDNNAIIKKALDK--RISDLKADAPQRDQEDDMNALIXXXX 1764
E L + R++D+ A K +++ R+ K + + +E +
Sbjct: 3349 LRLREVELEQLQALIYRQQDEIEANRKAIINEKYRLEGQKTEIDRLQREVNQMMEYASKD 3408
Query: 1763 XXXXXXXXXXKIVSNLEVNILILHEELQKEK---DDKTALIKDLVAAEPGKRTVNEIVSH 1593
I +++I EL KE+ +++T ++ KRT E+
Sbjct: 3409 RANLEKEKSEMIAQKHQMDI-----ELNKERGLIEERTQMLNTYEKEMDQKRTALEV--- 3460
Query: 1592 LESKSRSLKEHFLREEEDEV------LERSASNLAIMKAIREEELRKEKDGKSALVENGE 1431
E K + ++EE++++ L+R A ++ +K E+ R E+ + EN
Sbjct: 3461 -EMKELKYHKQAIQEEKNKLQQMKIELQREADDIKKLK----EKTRNERQSLEKMAEN-- 3513
Query: 1430 GCEAEKQGLEKTVLERRASNLDTMDAIHEE---ELRKEKVDKSALTEN----GEGCEAEK 1272
E EK L + + + D M +HE +++KEK + + E+ E ++EK
Sbjct: 3514 -LEKEKDDLAHLAEDTKRKD-DEMKVLHESALADIQKEKCNLEQMRESMFKQNEMIDSEK 3571
Query: 1271 QGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEI 1092
K ++ E + + + R + +K +E + + KN L
Sbjct: 3572 ----KKMILREDKLQQMQAEINRQQTEMDTKKSIIENERAAMTKKNQDLMT--------- 3618
Query: 1091 ERKLEASNLTHNDELHKEKDDKKSIMNDLDRVKAEKQVLESKVSDLETTYSTLNNELQQK 912
EL K+ +D + M + V EK++LES L+ L +L
Sbjct: 3619 -------------ELTKQSEDVEIQMKE---VLTEKELLESDRKLLKKDVENLQQKLLII 3662
Query: 911 MDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISEL 732
D+E+ +R+ LE K+ L++ DL+ +IE K + + + + +I +
Sbjct: 3663 ESDSESLKQDRELLENEKEVLKQMKTDLQGEAEEIE-KIKLETQHERQRVEEMTAQIQKD 3721
Query: 731 EEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRV 594
E + + D + + DI ++ + Q++L++ E Q+L++ +
Sbjct: 3722 REYLQKMNDNITREIHDIKYQEKQMKQKQDELDQLKTEIQNLQQEL 3767
Score = 67.8 bits (164), Expect = 4e-08
Identities = 122/593 (20%), Positives = 248/593 (41%), Gaps = 81/593 (13%)
Frame = -3
Query: 2027 DELLNEKD-DKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIK-- 1857
D + + D ++ I N + I++ +E + D+ K L+ E ++ D+ +++
Sbjct: 10757 DNKIKQTDLERHDIENSKEIVQKLMVKVEEQRKDIRLQKEELDIERQKIADEQGLVVQNK 10816
Query: 1856 ----------KALDKRISDLKA-----DAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVS 1722
K +D+ I K +A R ++++M ++I
Sbjct: 10817 AKLQNENERIKEMDEEIKKEKETLKEMEAHLRKEKEEMRSVIEETQRRKKEDLEKMSTDV 10876
Query: 1721 NLEVNILILHEELQKEKDDK-----TALIKDLVAAEPGKRTVNEIVSHL-ESKSRSLKEH 1560
N + L+ +L K++ ++ T L ++ ++E + + + K L +
Sbjct: 10877 NKQNQDLMNQRDLLKQEREEINHKWTQL----------QQRIDEFDAQVSKQKEEDLTKQ 10926
Query: 1559 FLREEEDEVLERSASNLAIMKAIRE-EELRKEKDGKSALVENGEGCEAEKQGLE--KTVL 1389
EEE + LE + + MK E E+++KEK+ + V + E +K+ L+ K+ L
Sbjct: 10927 KKMEEERKSLEETKIKIIEMKTKTEPEKIKKEKEKEEEEVMRAK-VEMKKEELDQIKSQL 10985
Query: 1388 ERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDAL 1209
ER S +D HE+ +K DK + + E E K K +E L++ +
Sbjct: 10986 ERVRSEID-----HEQ--KKLNDDKKMIEQEKEDLEKMKSEIMKQRQQMEEERSELDNKI 11038
Query: 1208 -QRDLDR--VMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIER---------------K 1083
Q DL+R + K+ ++K ++E + + +E E +IER K
Sbjct: 11039 KQTDLERHDIENSKEIVQKLMVEVEEQRKDIRLQKE--ELDIERQKIADEQGLVVQNKAK 11096
Query: 1082 LEASN---LTHNDELHKEKDDKKSIMNDLDRVKAE-KQVLES----KVSDLETTYSTLNN 927
L+ N ++E+ KEK+ K + L + K E + V+E + DLE + +N
Sbjct: 11097 LQNENERIKEMDEEIKKEKETLKEMEAHLRKEKEEMRSVIEETQRRQKEDLEKMSTDVNK 11156
Query: 926 ELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATI-----HDIEMKTGKDDDYNEAEK 762
+ Q M+ + ER+ + L++R+ + +A + D+ + +++ E+
Sbjct: 11157 QNQDLMNQRDLLKQEREEINHKWTQLQQRIDEFDAQVSKQKEEDLTKQKKMEEERKSLEE 11216
Query: 761 QTL---------------KKRISELEEAISILTDKAKKLLKDINIWL----SEVTELQED 639
+ K++ E EE + + K+ L I L SE+ Q+
Sbjct: 11217 TKIKIIEMKTKTEPEKIKKEKEKEEEEVMRAKVEMKKEELDQIKSQLERVRSEIDHEQKK 11276
Query: 638 LNKESK----EKQDLEKRVLELTSKLEKCICGARDGLSTIKEAWMSDCMVPDN 492
LN + K EK+DLEK E+ + ++ + + I++ ++ C + ++
Sbjct: 11277 LNDDKKMIEQEKEDLEKMKSEIMKQRQQMEEERSELENKIRQTYIEKCDIENS 11329
Score = 67.4 bits (163), Expect = 5e-08
Identities = 92/447 (20%), Positives = 194/447 (43%), Gaps = 36/447 (8%)
Frame = -3
Query: 1622 KRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNLAIMKAIREEELRKEKDG-KSAL 1446
+ T E++ LE + R+ K R L + +++K KD K
Sbjct: 80 RMTEPELIQELEWRQRNTKHTQTETGSPPSSPREKRRLEDKSGL-SSDIQKRKDSLKRRR 138
Query: 1445 VENGEGCEAEKQGLEKTVLERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQG 1266
E E ++ E T ER + +D M ++++++++ + + +T EK
Sbjct: 139 FETMRAIEQIEKLWEGTKQER--TEIDNM----KQKIQRQQDEITRMT-------TEKGQ 185
Query: 1265 PEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIER 1086
E+T+ ++ I + + + R+ + V E++ +E+ SDL+A+ +SL Q+ E ER
Sbjct: 186 LERTITHMKAEIDHIRERMDRNKEEVNRERERVEQMRSDLQAEQSSL--QQKRDEIMTER 243
Query: 1085 K----LEASNLTHNDELHKEKDDKKSIMNDLDRVKAEKQV----LESKVSDLETTYSTL- 933
+ + L +EL ++ K M ++++K+ QV +E K+ + + +
Sbjct: 244 QNLEMIRYETLRQQEELESNRESTKHEMERMEQMKSAIQVQINEIEMKIGETQKAKDLME 303
Query: 932 ---------NNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDD 780
NEL++K +D +RD E +K L++ +++E H+ E + +
Sbjct: 304 QMKAEIEDEKNELEKKKED---IKRQRDQFEQIKLDLQQVKMEMEQRWHETEKEGLEQRA 360
Query: 779 YNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEV--TELQEDLNKESK----- 621
+ EK+ LK E++ + ++ ++ K + +S++ L+E+ E+K
Sbjct: 361 VIQREKEQLKYLQDEIQR-VREEVERNREFSKQEHARISQLRAQALEENNLIENKWHDIL 419
Query: 620 -EKQDLEKRVLELTSKLEKCICGARDGLSTIKEAW----MSDCMVPDNWVPFEDLVQGFS 456
+++DLE+ E+ E+ + +K+ W + + + + E V
Sbjct: 420 RKEKDLEEMKHEIERGREELVMNG----ELVKKEWEKIEQAKVDIQSHMISMEGRVDEIK 475
Query: 455 RKTSPLDITKT-----CDAVDISEDST 390
R+T L KT DA++ +D T
Sbjct: 476 RETERLKHIKTEMQRDKDALEKQKDDT 502
Score = 65.1 bits (157), Expect = 2e-07
Identities = 117/597 (19%), Positives = 242/597 (40%), Gaps = 108/597 (18%)
Frame = -3
Query: 2033 LNDELLNEKDDKKCIVN--------DRNILEAAKQALEYKVADLEAAKTTLNDELERKKD 1878
LN+ LN+ K ++ ++ +E K ++ + DL+ +T LN + + +D
Sbjct: 1889 LNELTLNQIKTKSDVLEKISELNSQQKDEIENEKSKIKIREYDLQQMQTDLNRQQKEMQD 1948
Query: 1877 DNNAII--KKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLE-VN 1707
NA+ K L K ++ A Q Q DM NL+
Sbjct: 1949 IQNAVFMEKSELKKSQDEI---AEQLKQVGDMMQFTQNEK-------------DNLDRER 1992
Query: 1706 ILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEV-L 1530
I+ ++LQ E+D L ++L + + K+ V LE SL E+ ++ L
Sbjct: 1993 AAIIEQKLQMERDMTHLLNRELESLKLVKKEVLNEKRLLEDCRISLMRDMQDLEQMKINL 2052
Query: 1529 ERSASNLAIMKAIREEELRKEKDGKSALVENGEGCE----AEKQGLEKTVLERRASNLDT 1362
ER + + + EE K + L E+ E AEKQ LE +E + +
Sbjct: 2053 EREKEEMQLQRQSIAEEKDKLESVLQTLAEDTEKLRIDTLAEKQKLEDAAVELQKERDEI 2112
Query: 1361 MDAIHEEELRKEKVDK----------------------SALTENGEGC------------ 1284
M+ E + ++E VDK +A+ EN
Sbjct: 2113 MNIAEETKRKREDVDKIRVGIEKQEITFKDLKADLQKEAAIVENQRQAVQKDIQNVKDME 2172
Query: 1283 ---EAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQ 1113
+ E+Q ++ V ++E +L D +Q ++D+ E+Q +E + +LE + + L +++
Sbjct: 2173 VQIQKERQYMDRLVEEIEKRTKAL-DEMQMEVDK---ERQEVESKRDELEQETSKLREDE 2228
Query: 1112 EGH----------EAEIERK-----LEASNLT----------------HNDELHKEK--D 1032
+ +AEI+++ L++ N++ N+ +K+K D
Sbjct: 2229 DEFSRQKEKNNIIQAEIQKESDNLELQSENISKERTIFELEKEHLGLRENEAEYKQKQID 2288
Query: 1031 DKKSIMN----DLDRVKAEKQVLESKVSDLETTYSTLNNELQQKMDDNEAFLNERDGLEA 864
+ ++ + +++++A+K K ++T L+++ + E+ E + +E
Sbjct: 2289 ELQNKLRMEKVQVEQMQADKDQQRKKAEYVKTARGRETTALEEQRQEMESLREEYENVEK 2348
Query: 863 VKQGLEKRVLDLEATIHDIEMKTGKDDDYNEA----------EKQTLKKRISELEEAISI 714
K+ + ++ E+ + +EM+ Y E ++Q +K I ++ + I
Sbjct: 2349 QKKHVNEQKELFESRMKSLEMENEAMKKYKEKLDKEYEDLQFQRQLFEKEIQQMRTELQI 2408
Query: 713 LTDKAKKLLKDINIWLSEV------TELQEDLNKESK--EKQDLEKRVLELTSKLEK 567
+ ++ K++ I V E Q+ + ++SK E ++ K++ S++EK
Sbjct: 2409 EAENIERKKKELEIQKPAVYTETYMLETQKPVVEKSKTDELDEVRKKINADLSEVEK 2465
Score = 65.1 bits (157), Expect = 2e-07
Identities = 108/563 (19%), Positives = 242/563 (42%), Gaps = 74/563 (13%)
Frame = -3
Query: 2033 LNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIK- 1857
L++++ +K I + I+E +E + D++ K L+ E ++ D+ N +++
Sbjct: 10481 LDNKIQQTNLEKHDIEKSKEIVEKLMVEVEEQRKDIQLQKEELDIERQKIADEQNLLVQN 10540
Query: 1856 -----------KALDKRISDLKADAPQRD-----QEDDMNALIXXXXXXXXXXXXXXKIV 1725
K +D+ I + + + +++++ ++I +
Sbjct: 10541 KAKLQNENERIKKVDEEIKKERETLREMEIHLKKEKEELRSIIEETQRRKEDLEKMSTDI 10600
Query: 1724 SNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREE 1545
+ ++++ + L++E+++ + L ++ ++E + + + L + + EE
Sbjct: 10601 NEQKLHLKNQRDLLEQEREEINHEMTQL------QQRIDEFDAQVSKQREDLTKQEM-EE 10653
Query: 1544 EDEVLERSASNLAIMKAIRE-EELRKEKDGKS-----ALVENGEGCEAEKQGLEKTVLER 1383
E + LE + + + MK E +E+ +EK+ + +VE E E+ K+ L+R
Sbjct: 10654 ERKSLEETKARIIEMKTKAELQEIMQEKEEEDEEEMRVIVE----MEREELNQIKSELKR 10709
Query: 1382 RASNLDTMDAIHEEE--------LRKEKVD----KSALTENGEGCEAEKQGPEKTV--LD 1245
S +D HE++ + +EK D KS + + E E+ + + D
Sbjct: 10710 VRSEID-----HEQKKLNDDKKIIEQEKEDLEKMKSEIMTQRQQMEEERSELDNKIKQTD 10764
Query: 1244 LEP-TIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASN 1068
LE I + + +Q+ + +V +++ + + +L+ + + D Q G + + KL+ N
Sbjct: 10765 LERHDIENSKEIVQKLMVKVEEQRKDIRLQKEELDIERQKIADEQ-GLVVQNKAKLQNEN 10823
Query: 1067 ---LTHNDELHKEKDDKKSIMNDLDRVKAE-KQVLES----KVSDLETTYSTLNNELQQK 912
++E+ KEK+ K + L + K E + V+E K DLE + +N + Q
Sbjct: 10824 ERIKEMDEEIKKEKETLKEMEAHLRKEKEEMRSVIEETQRRKKEDLEKMSTDVNKQNQDL 10883
Query: 911 MDDNEAFLNERDGLEAVKQGLEKRVLDLEATI-----HDIEMKTGKDDDYNEAEKQTL-- 753
M+ + ER+ + L++R+ + +A + D+ + +++ E+ +
Sbjct: 10884 MNQRDLLKQEREEINHKWTQLQQRIDEFDAQVSKQKEEDLTKQKKMEEERKSLEETKIKI 10943
Query: 752 -------------KKRISELEEAISILTDKAKKLLKDINIWL----SEVTELQEDLNKES 624
K++ E EE + + K+ L I L SE+ Q+ LN +
Sbjct: 10944 IEMKTKTEPEKIKKEKEKEEEEVMRAKVEMKKEELDQIKSQLERVRSEIDHEQKKLNDDK 11003
Query: 623 K----EKQDLEKRVLELTSKLEK 567
K EK+DLEK E+ + ++
Sbjct: 11004 KMIEQEKEDLEKMKSEIMKQRQQ 11026
Score = 62.8 bits (151), Expect = 1e-06
Identities = 107/536 (19%), Positives = 227/536 (42%), Gaps = 55/536 (10%)
Frame = -3
Query: 2027 DELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKAL 1848
+ L KD+ + +R+ LE K ++E NDE++++K + K L
Sbjct: 7511 ETLRGMKDEVQAARKERSELENMKLEFLTMKKNMEKTYEQQNDEIQKEKQQIESS-KMLL 7569
Query: 1847 DKRISDLKADAPQRDQED-----DMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEEL 1683
+ +DL+ + +++ D L+ KI+ NLE L EE
Sbjct: 7570 SRERNDLEQNRADLERQKQIMALDKQKLLAENELLEREKADVIKIIENLES----LREEA 7625
Query: 1682 QKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVLE--RSASNL 1509
+E+ +TA + +R E++ +E+ S E F +++++E R L
Sbjct: 7626 TRERATETA--------QATRRDSEELMQKMEALSM---EDFQEASKNQMVELKRQIDKL 7674
Query: 1508 AIMKAI---REEELRKEKDG-----------KSALVENGEGCEAEKQGLEKTVLERRASN 1371
+KA ++ EL+K K +S ++++ + +++ + LE ++R+ +
Sbjct: 7675 IELKADLLQQQTELKKTKADLKQQMDDLEKTRSEILKHEKDTDSKTRELELIEIQRQKDD 7734
Query: 1370 LDT------MDAIHEEELRKEKV-DKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLN-- 1218
L+T ++ E LR E V +K L + + ++ EK D+ +N
Sbjct: 7735 LETRIQKLTLEKRDLEVLRSEIVLEKKDLDQKMKQVIRKRDEMEKIRSDIANATEEINRE 7794
Query: 1217 ----DALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQE-------------GHEAEIE 1089
+ L+ ++ + + L +R ++LE + ++ TD + + E+E
Sbjct: 7795 RQELEILRNNVQSARHDFELLLERTANLEDEESAATDIERLVLEVVKIREMVRNLKGEME 7854
Query: 1088 RKLEASNLTHNDELHKEKDDKKSIMNDLDRVKAEKQVLESKVS-------DLETTYSTLN 930
R++E S + DE K + + + D+ +++ L ++ +LE + L
Sbjct: 7855 RRMEKSKV-EIDEKEIFKSEIQRFIQDIGQIRENLGGLGEEIEKTRRDKRELEKMRAELA 7913
Query: 929 NELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLK 750
+ Q++ E ER+ LE +K + + D+E +E K++ + Q K
Sbjct: 7914 EKQQEQESMREMLHKEREELEQLKDEINREKEDVEIRRELVEAVIDKEEMKEFTDIQKYK 7973
Query: 749 KRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLN-KESKEKQDLEKRVLEL 585
+ + + E +LT K+ L +N + ++ + E++N + K++ +LE EL
Sbjct: 7974 EELQSVTE--ELLT--KKRDLDQLNSDVQDLRQTIEEINIQHGKKRAELEGIGFEL 8025
Score = 62.4 bits (150), Expect = 2e-06
Identities = 121/544 (22%), Positives = 221/544 (40%), Gaps = 48/544 (8%)
Frame = -3
Query: 2081 QALESKVSVFEAAIATLNDELLNEKDDKKCIVNDRNILEAAKQ--ALEYKVADLEAAK-- 1914
Q L+++ + E + T ND LL E +K+ ND + E K+ ALE + D+ K
Sbjct: 13203 QLLQTEKEILEKS-KTEND-LLREDLEKQRKRNDLTLQELRKEKMALEQMITDITKEKDA 13260
Query: 1913 -TTLNDELERKKDD--NNAIIKKALDKRISDLKADAPQRD-----QEDDMNALIXXXXXX 1758
+L +E+ K+ + N K + DL+ R Q+ +++ I
Sbjct: 13261 VASLQNEVSLKQHELKNKETELDEQRKEMDDLRMQLEMRQNSTNKQQQEVDVFIVENMKM 13320
Query: 1757 XXXXXXXXKIVSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKS 1578
++LE +L EE ++ +D+ P K + LE +
Sbjct: 13321 R----------NDLESMKTLLDEERRQLQDNIKTFEDQKNVLHPSKTDAVQQTDELEKFT 13370
Query: 1577 RSLK---EHFLREEEDEVLERSASNLAIMKAIRE--------EELRKEKDGKSALVENGE 1431
+K EH +E E E N I+K+ E E ++E GK A +E+ E
Sbjct: 13371 TDIKTEKEHVEKERE----EIDVLNKEIIKSKEELQSLNLEIEMFKQEIAGKRAQIESLE 13426
Query: 1430 GCEAE----KQGLEKTVLERRASNLDTMDAIHEEELRKE-KVDKSALTENGEGCEAEKQG 1266
A+ ++ V + ++ + E EL+ + K+ L E EAEK
Sbjct: 13427 QLRADLLAGADDIKTLVQTEKQMAIEDTEKKTEVELQMNLQKQKNELEELRNTIEAEKHQ 13486
Query: 1265 PEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIER 1086
E + L+ + D + + +E+ LEK S+L + L + + + E+ER
Sbjct: 13487 VENRKIMLDKQQKEVEDIMTV----IKSERDVLEKEKSELNKLSHVLNEKVQREQEELER 13542
Query: 1085 KLEASNLTHNDELHKEKDDKKSIMNDLDRVKAEKQVLESKVSDLETTYSTLNNELQQKM- 909
LE KE+DD I N +++EKQ +E + ++L+ + + ++ +
Sbjct: 13543 LLE-----------KERDD---IENCKKIIESEKQSIERERAELKRLKEEVEVQHERTLL 13588
Query: 908 -DDNEAFLNERDGLEA-----------VKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAE 765
D E++ LE +K+ ++++ +L+ +IE K +++ + E
Sbjct: 13589 QQDKNMIQKEKEHLEGEKARTTEEIHNLKEEIKRKSSELDMLNKEIEAKRQEEELHGLPE 13648
Query: 764 ----KQTLKKRISELEEAI--SILTDKAKKL-LKDINIWLSEVTELQEDLNKESKEKQDL 606
+ LKK L E I TD ++K LK + T L E + + ++ L
Sbjct: 13649 EIEIEDHLKKEDDVLREEIIKKQQTDASQKFQLKTTSRDAETQTSLDEITKTDERRQRAL 13708
Query: 605 EKRV 594
E+ V
Sbjct: 13709 EETV 13712
Score = 62.0 bits (149), Expect = 2e-06
Identities = 117/582 (20%), Positives = 218/582 (37%), Gaps = 78/582 (13%)
Frame = -3
Query: 2081 QALESKVS-VFEAAIATLND--ELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKT 1911
Q LE+KV V + T D EL +E ++K I+ + N + Q L+ + E K+
Sbjct: 14254 QTLETKVQDVLQLTDYTTQDQEELHDEMENKMKIILELNEAKKDLQKLKEECRSAEEEKS 14313
Query: 1910 TLNDELERKKDDNNAIIKKALD-----KRISDLKADAPQ--------------------- 1809
+ + LER+++ + + L ++ +K + Q
Sbjct: 14314 VIMESLERRRNSLEKVQSEVLSLTQEIDHLAQIKTEMQQIEIKMQIQTRSVATQWETDVQ 14373
Query: 1808 ----RDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDKTALIKDL 1641
++ + + V+ LE L E+Q+ +D ++D+
Sbjct: 14374 IQQGQEATETTGHITKKSEEEISAKKTKQPTVTKLEDT---LTSEVQEMRDSLNKEMEDV 14430
Query: 1640 VAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNLAIMKAIRE-EELRKEK 1464
+ + + + +S ++ E F R E+ + E+S + +++ + E+L
Sbjct: 14431 ARMKTIMKMEKDQLEQAKSDIQTQMEEFERNMEEAMEEKSRNEEKLLQLTHDKEDLSNTL 14490
Query: 1463 DGKSALVENG----------------------EGCEAEKQGLEKTVLERRASNLDTMDAI 1350
D K+ +EN E E E L++T ER T D
Sbjct: 14491 DKKNKEIENNTETSLKKIAQLETTIVLMKKDKENIENELLQLKQTEQEREIQR-GTDDTS 14549
Query: 1349 HEEELRKEKVD-KSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQ 1173
+E E EKV K+ L +N E +K+ + L L D+ + D +R E Q
Sbjct: 14550 NEREKYDEKVTYKTELEDNKE----KKKPDRDSSLKLTDA-----DSAKTDGER---EAQ 14597
Query: 1172 ALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASNLTHNDELHKEKDDKKSIMNDLDRVK 993
LE + D+ T +QE ELH E ++K I+ +L+ K
Sbjct: 14598 TLETKVQDVLQLTDDTTQDQE-------------------ELHDEMENKMKIILELNEAK 14638
Query: 992 AEKQVLESKVSDLETTYSTLNNELQQKMDDNE-------AFLNERDGLEAVKQGLEKRVL 834
+ Q L+ K E S + L+++ + E E + L +K +++
Sbjct: 14639 KDLQKLKEKCRSAEEEKSVIMESLERRRNSLEKVQSEVLTLTQEIEHLAQIKTEMQQIET 14698
Query: 833 DLEATIHDIEMKTGKDDDYNEAEKQTLKKR---ISELEEAISILTDKAKKLLKDINIWLS 663
++ + + D + ++ + R + EE IS K + K + S
Sbjct: 14699 KMQRQTRSVATQWETDVQIQQEGQEATETRGHITKKSEEEISAKKTKQPTVTKLEDTLTS 14758
Query: 662 EVTELQEDLNKESK-----------EKQDLEKRVLELTSKLE 570
EV E+++ LNKE + EK LE+ +L ++E
Sbjct: 14759 EVQEMRDSLNKEMEDVERMKTMMKMEKDQLEQAKSDLQRQME 14800
Score = 60.5 bits (145), Expect = 6e-06
Identities = 105/514 (20%), Positives = 211/514 (41%), Gaps = 39/514 (7%)
Frame = -3
Query: 1985 NDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKALDKRISDLKADAPQR 1806
++ ++ EA Q AD+E ELE+ KD+ K + K DL+ +
Sbjct: 1701 DELSLREATLQTATQTTADMELQLELQKQELEQTKDEMER-TKLEVQKGWVDLQTQIAES 1759
Query: 1805 DQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDKTALIKDLVAAEP 1626
++++M + +++ + ++ E+ E D K L K+ E
Sbjct: 1760 REKEEMVRI---------ELEKARDVLNRIRQDVET--EKQTMEADLKFTLAKEFENLEA 1808
Query: 1625 GKRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNLAIMKAIREEELRKEKDGKSAL 1446
++ + + LE+ L + E +ERS N+ +E + ++ L
Sbjct: 1809 QRKMMEDEKRALENMKYEL------QRESGYIERSKHNM-------HDERQNMENWAEKL 1855
Query: 1445 VENGEGCEAEKQGLE--KTVLERRASNLDTMDAIHEEELRKEKVDKSAL-------TENG 1293
+ E E ++ ++ +T R +L+ + ++E L + K L ++
Sbjct: 1856 KQEWEELEKKRHDMQQLQTERSREIKDLENLRELNELTLNQIKTKSDVLEKISELNSQQK 1915
Query: 1292 EGCEAEKQGPEKTVLDLEPTIPSLN---DALQRDLDRVMAEKQALEKRCSDLEAKNASLT 1122
+ E EK + DL+ LN +Q + V EK L+K ++ + +
Sbjct: 1916 DEIENEKSKIKIREYDLQQMQTDLNRQQKEMQDIQNAVFMEKSELKKSQDEIAEQLKQVG 1975
Query: 1121 DNQEGHEAE-----------IERKLEAS-NLTH--NDELHKEKDDKKSIMNDLDRVKAEK 984
D + + E IE+KL+ ++TH N EL K KK ++N+ ++ +
Sbjct: 1976 DMMQFTQNEKDNLDRERAAIIEQKLQMERDMTHLLNRELESLKLVKKEVLNEKRLLEDCR 2035
Query: 983 QVLESKVSDLETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGL----EKRVLDLEA-- 822
L + DLE L E ++ ++ E+D LE+V Q L EK +D A
Sbjct: 2036 ISLMRDMQDLEQMKINLEREKEEMQLQRQSIAEEKDKLESVLQTLAEDTEKLRIDTLAEK 2095
Query: 821 -TIHD--IEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTE 651
+ D +E++ +D+ N AE+ KR E + I + +K + KD+ L +
Sbjct: 2096 QKLEDAAVELQKERDEIMNIAEE---TKRKREDVDKIRVGIEKQEITFKDLKADLQKEAA 2152
Query: 650 LQED----LNKESKEKQDLEKRVLELTSKLEKCI 561
+ E+ + K+ + +D+E ++ + +++ +
Sbjct: 2153 IVENQRQAVQKDIQNVKDMEVQIQKERQYMDRLV 2186
>ref|XP_005159741.1| PREDICTED: nesprin-1 isoform X5 [Danio rerio]
Length = 15580
Score = 103 bits (256), Expect = 8e-19
Identities = 128/547 (23%), Positives = 231/547 (42%), Gaps = 48/547 (8%)
Frame = -3
Query: 2033 LNDELLNEKDDKKCIVND----RNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNA 1866
+ +EL EK+ + D + IL+ K A E +ADL+ K+ L + E
Sbjct: 5015 MTEELKKEKESFTHLAEDTKTEKKILDKMKVANESLMADLQKEKSNLEEMRENISKQTED 5074
Query: 1865 IIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEE 1686
K+ R+ + + + Q + + K V +L+ + L +
Sbjct: 5075 SEKEKEKIRLREDELEQLQAEIHKQQGEIKMEKSNNESERAAIIKDVKDLQHKMFSLDRD 5134
Query: 1685 LQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVL-------- 1530
L+ K D+ A E + + +I + L+ K+ +++ L + D
Sbjct: 5135 LESLKLDREAF-------ENEREVLKQIKTDLKRKAEEIEKIKLETQHDRQRVEEMTAQI 5187
Query: 1529 --ERSASNLAIMKAIREEELRKE-----KDGKSALVENGEGCEAEKQGLEKT--VLERRA 1377
ER N I + R++ + E K+ A+ + + E EK LEKT L R
Sbjct: 5188 QKERDKINNLIEETNRKDMVLNEIKTEIKEKIKAIESDRDMLEKEKHDLEKTRSKLLRAK 5247
Query: 1376 SNLDTMDAIHEEELRKEKVDKSALTE------NGEGCEAEKQGPEKTVLD-LEPTIPSLN 1218
NL+ I E++KE+ D + E + + E+ ++ LD L+ I +L
Sbjct: 5248 ENLEKQRKIKLAEIQKEREDLEKMNEKFTIEIHDIKHQEEQMKQKQDELDQLKTEIQNLQ 5307
Query: 1217 DALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIER--KLEASNLTHNDELH 1044
L+++ + +M ++ L+ R S+L+ + ++ D E + E ++ K + E+
Sbjct: 5308 QELEKEKEIIMKDRSQLDLRQSELDKQQTNVNDIMETMKNERKQLDKDKEETEEQKQEME 5367
Query: 1043 KEKDD----KKSIMNDLDRVKAEKQVLESKVSDLETTYSTLNNELQQKMDDNEAFLNERD 876
KEK D +KS+ DL +K +KQVLE + S LE L E + E NER
Sbjct: 5368 KEKHDFDQSRKSLDEDLKMMKLQKQVLEDEKSKLEQMKIELEREAVEIRKIKEEIQNERQ 5427
Query: 875 GLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTL------KKRISELEEAISI 714
LE + + L++ DL + + D+ A + TL K + E+ E IS
Sbjct: 5428 NLEKMTEALKEEREDL---AEETKKNNQVLDEMKVANESTLADILREKSNLEEMRENISK 5484
Query: 713 LTDKAKKLLKDINIWLSEVTELQEDLNKE----SKEKQDLEKRVLELTSKLE----KCIC 558
T+ + +++ + E+ +LQ +++K+ KEK ++E + +E K IC
Sbjct: 5485 QTEDVENKKENLRLREDELRQLQAEIHKQQREIEKEKINIESERAAIIKDVEDLQHKIIC 5544
Query: 557 GARDGLS 537
RD S
Sbjct: 5545 LDRDAES 5551
Score = 97.1 bits (240), Expect = 6e-17
Identities = 130/534 (24%), Positives = 241/534 (45%), Gaps = 47/534 (8%)
Frame = -3
Query: 2027 DELLNE-----KDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLND-------ELERK 1884
D +LNE K+ K I +DR++LE K LE + L AK L E++++
Sbjct: 5205 DMVLNEIKTEIKEKIKAIESDRDMLEKEKHDLEKTRSKLLRAKENLEKQRKIKLAEIQKE 5264
Query: 1883 KDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNI 1704
++D + +K I D+K Q Q+ D + L+ I
Sbjct: 5265 REDLEKMNEK-FTIEIHDIKHQEEQMKQKQDE--------------------LDQLKTEI 5303
Query: 1703 LILHEELQKEKD----DKTALIKDLVAAEPGKR--TVNEIVSHLESKSRSL-KEHFLREE 1545
L +EL+KEK+ D++ L DL +E K+ VN+I+ ++++ + L K+ EE
Sbjct: 5304 QNLQQELEKEKEIIMKDRSQL--DLRQSELDKQQTNVNDIMETMKNERKQLDKDKEETEE 5361
Query: 1544 EDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLD 1365
+ + +E+ + + +E+L+ K K L + E K LE+ +E R
Sbjct: 5362 QKQEMEKEKHDFDQSRKSLDEDLKMMKLQKQVLEDEKSKLEQMKIELEREAVEIRKIK-- 5419
Query: 1364 TMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVM 1185
+ I E EK+ + AL E E E + + + +++ S + R+ +
Sbjct: 5420 --EEIQNERQNLEKMTE-ALKEEREDLAEETKKNNQVLDEMKVANESTLADILREKSNLE 5476
Query: 1184 AEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASNLTHNDELHKEKDDKKSIMNDL 1005
++ + K+ D+E K +N E E+ R+L+A E+HK++ + I +
Sbjct: 5477 EMRENISKQTEDVENKK----ENLRLREDEL-RQLQA-------EIHKQQ---REIEKEK 5521
Query: 1004 DRVKAEKQVLESKVSDLETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLE 825
+++E+ + V DL+ L+ + + D EAF NE++ L+ +K LE+ ++E
Sbjct: 5522 INIESERAAIIKDVEDLQHKIICLDRDAESLKLDREAFENEKEVLKQMKTELEREADEIE 5581
Query: 824 ----ATIHD--------IEMKTGKDDDYNEAEK-----QTLKKRISELEEAI-SILTDK- 702
T HD +++ +D+ N E+ L ++ ++EE I SI +DK
Sbjct: 5582 KIKLETQHDRQRVEEMAAQIQKDRDEINNLIEETNRKDMVLNEKNRDIEEKIKSIQSDKD 5641
Query: 701 -AKKLLKDINIWLSEVTELQEDLNKE--------SKEKQDLEKRVLELTSKLEK 567
+K D+ SE+ +++EDL K+ KE++DLEK +T ++ +
Sbjct: 5642 MLEKEKHDLEKTRSELYKVKEDLEKQKENTLAEIQKEREDLEKMNENITREMHE 5695
Score = 93.6 bits (231), Expect = 6e-16
Identities = 132/583 (22%), Positives = 250/583 (42%), Gaps = 40/583 (6%)
Frame = -3
Query: 2027 DELLNEKDDK-----KCIVNDRNILEAAKQALE------YKVA-DLEAAKTTLNDELERK 1884
D +LNEK+ K I +D+++LE + LE YKV DLE K E++++
Sbjct: 6075 DMVLNEKNRDIEEKIKSIQSDKDMLEKERHNLEKTRSELYKVKEDLEKQKENTLAEIQKE 6134
Query: 1883 KDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNI 1704
++D + + + + + ++K Q +Q+ D + L+ I
Sbjct: 6135 REDVEKM-NENITREMHEIKHQEEQMNQKQDE--------------------LDQLKTEI 6173
Query: 1703 LILHEELQKEKD----DKTALIKDLVAAEPGKR--TVNEIVSHLESKSRSL-KEHFLREE 1545
L +EL+KEK+ D++ DL +E K+ +N+I+ ++++ + L K+ EE
Sbjct: 6174 QNLQQELEKEKEIIMKDRSQF--DLRQSELDKQQTNMNDIMETMKNERKQLDKDKEEMEE 6231
Query: 1544 EDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLD 1365
+ + +E+ + + +++L+ K K E E K LE+ E R +
Sbjct: 6232 QKQEMEKEKHDFDQSRKSLDKDLKMMKLQKQVFEEEKNKLEQMKIELEREADEIRKIKEE 6291
Query: 1364 TMDAIHE-----EELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRD 1200
T + EEL+KEK + L E+ + E+ +LD + N++L D
Sbjct: 6292 TQNERQSLEKMTEELKKEKESFTHLAEDTK--------KEQEILD---KVKVANESLMAD 6340
Query: 1199 LDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIER--KLEASNLTHNDELHKEKDDK 1026
L + EK LE+ ++ + + + +E + +L+A E+ KEK +
Sbjct: 6341 LQK---EKSNLEEMRENISKQTEDVENKKENLRLREDELWQLQAEIYKQQREIEKEKIN- 6396
Query: 1025 KSIMNDLDRVKAEKQVLESKVSDLETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLE 846
+++E+ + V DL+ +L+ + + D EAF NER+ L+ +K LE
Sbjct: 6397 ---------IESERAAIIKNVEDLQHKIISLDRDSESLKLDREAFENEREVLKQMKTELE 6447
Query: 845 KRVLDLE----ATIHD----IEMKTGKDDDYNEAEKQTLKKRI------SELEEAISILT 708
+ ++E T H+ EM + N KQ K ++ E+E+ +
Sbjct: 6448 READEIEKIKLETQHERQRVEEMTADFMETMNNERKQLDKNKVMIEEQKQEMEKKRDDMD 6507
Query: 707 DKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLELTSKLEKCICGARDGLSTIK 528
K L +D+ + ++ L+E+ NK + K LE+ E+ SK+++ R L +
Sbjct: 6508 QSRKSLDEDLKMMKAQKQVLEEEKNKLEQMKIGLEREADEI-SKIKEETQNERQNLEKMA 6566
Query: 527 EAWMSDCMVPDNWVPFEDLVQGFSRKTSPLDITKTCDAVDISE 399
A + E L + RK LD K + +++
Sbjct: 6567 NALKEE---------REYLAEEIKRKNQVLDKIKVANESTLAD 6600
Score = 91.7 bits (226), Expect = 2e-15
Identities = 116/521 (22%), Positives = 217/521 (41%), Gaps = 35/521 (6%)
Frame = -3
Query: 2045 AIATLNDELLNEKDDKKCIVND----RNILEAAKQALEYKVADLEAAKTTLNDELERKKD 1878
++ + +EL EK+ + D + IL+ K A E +A+L+ K+ + E
Sbjct: 3885 SLEKMTEELKREKESFTHLAEDTKKEQEILDEIKVANESLMAELQKEKSNFEEMRENISK 3944
Query: 1877 DNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILI 1698
+ K + R+ + + Q + + KIV +L+ I+
Sbjct: 3945 QTEDVKNKKENLRLREDELGQLQAEIHKQQREIEKEKSNIESERAAIIKIVEDLQHKIIS 4004
Query: 1697 LHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEE---DEVLE 1527
L + + K D+ A + + K + +E + R EE E
Sbjct: 4005 LDRDAESLKLDREAFENEREVLKQMKTELERETDEIEKIKLETQHDRQRVEEMTAQITKE 4064
Query: 1526 RSASNLAIMKAIREEELRKEKDGK-----SALVENGEGCEAEKQGLEKTV---------L 1389
R N I + R++ + EK+ ++ + + E EK LEKT L
Sbjct: 4065 RDKINNLIEETNRKDMVLNEKNRDIEEKIKSIQSDKDMLEKEKHNLEKTRSELYKVKEDL 4124
Query: 1388 ERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKT--VLDLEPTIPSLND 1215
E++ N T+ I +E EK++++ E E E+Q +K + L+ I +L
Sbjct: 4125 EKQKEN--TLAEIQKEREDLEKMNENITIEMHEIKHQEEQMKQKQDELDQLKTEIQNLQQ 4182
Query: 1214 ALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEG--HEAEIERKLEASNLTHNDELHK 1041
L+++ + +M ++ L+ R S+L+ + ++ D E +E ++ K + E+ K
Sbjct: 4183 ELEKEKEIIMKDRSELDLRQSELDKQQTNMNDIIETMKNERKLLDKDKEEMEEQKQEMEK 4242
Query: 1040 EKDDK----KSIMNDLDRVKAEKQVLESKVSDLETTYSTLNNELQQKMDDNEAFLNERDG 873
E+D+ KS+ DL +K +KQV+E + + LE L E + E NER
Sbjct: 4243 ERDNMDQSIKSLDEDLKMMKLQKQVIEEEKNKLEQMKFELQREADEIRKIKEETQNERQS 4302
Query: 872 LEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTL------KKRISELEEAISIL 711
LE + + L K DL + + D+ A K ++ K+ + E+ E IS
Sbjct: 4303 LEKMTKALIKEREDLVHLAEYTKREKEMLDEMQVANKSSMADLQREKRILEEMRENISKQ 4362
Query: 710 TDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLE 588
T+ + + + E+ +LQ ++ K+ E D+EK +E
Sbjct: 4363 TEDIENEKEKSKLREDELKKLQTEVQKQQSE-IDMEKTNIE 4402
Score = 91.7 bits (226), Expect = 2e-15
Identities = 117/514 (22%), Positives = 225/514 (43%), Gaps = 33/514 (6%)
Frame = -3
Query: 2027 DELLNEKDDK-----KCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAI 1863
D +LNE D K I +D+++LE + LE ++L AK L + E ++ D +
Sbjct: 4535 DMVLNEMDRDIEEKIKSIQSDKDMLEKERHNLEKTRSELARAKENLETQREIERKDIEKM 4594
Query: 1862 IKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEEL 1683
KK + + + ++K Q Q+ D + L+ I L +EL
Sbjct: 4595 -KKNISREMHEIKHQEEQMKQKQDE--------------------LDQLKTEIQNLQQEL 4633
Query: 1682 QKEKDD--KTALIKDLVAAEPGKR--TVNEIVSHLESKSRSL-KEHFLREEEDEVLERSA 1518
+KEK+ K DL +E K+ +N+I+ ++++ + L K+ EE+ + +E+
Sbjct: 4634 EKEKEIIMKARSQLDLRQSELDKQQTNMNDIMETMKNERKQLDKDKEETEEQKQEMEKEK 4693
Query: 1517 SNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHEEE 1338
+ + +E+L+ K K + E E K K LER A +E
Sbjct: 4694 HDFDQSRKSLDEDLKMMKLQKQVIEE-----EKSKLKQMKIELEREA-----------DE 4737
Query: 1337 LRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKR 1158
+RK K + T+N E+Q EK L+ L++ +R + K A E
Sbjct: 4738 IRKVKEE----TQN------ERQIFEKMTEALKKEREDLSEDAKRKNQVLDEMKVANEST 4787
Query: 1157 CSDLEAKNASLTDNQEG---HEAEIERKLEASNLTHND------ELHKEKDDKKSIMNDL 1005
+D+ + ++L + +E ++E K E L E+HK++ + + +++
Sbjct: 4788 LADILRERSNLQEMRENISKQTEDVENKKEKIRLREEKLKQLQAEIHKQQSETEKEKSNI 4847
Query: 1004 DRVKAEKQVLESKVSDLETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLE 825
+R E+ + V DL++ +L+ + + D EAF NE++ L+ +K LE+ ++E
Sbjct: 4848 ER---ERAAIIKDVEDLQSKIISLDRDAESLKLDREAFENEKEELKQMKTELEREADEIE 4904
Query: 824 ----ATIHDIEMKTGKDDDYNEA----------EKQTLKKRISELEEAISILTDKAKKLL 687
T H+ + D+ E K+ ++++ E+E+ + K L
Sbjct: 4905 KIKLETQHERQRVEEMTADFMETMNNERKQLNKNKEEMQEQKQEMEKERHDMDQSRKSLD 4964
Query: 686 KDINIWLSEVTELQEDLNKESKEKQDLEKRVLEL 585
K++ + + ++E+ NK + K +LEK E+
Sbjct: 4965 KNLKMMKLQKQVIEEEKNKLEQMKIELEKEADEI 4998
Score = 91.3 bits (225), Expect = 3e-15
Identities = 133/567 (23%), Positives = 248/567 (43%), Gaps = 62/567 (10%)
Frame = -3
Query: 2081 QALESKVSVFEAAIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADL-----EAA 1917
+ LES + + + L +LL + D + + DR +LE K+ L+ DL E
Sbjct: 3639 ELLESDRKLLKKDVENLQQKLLIIESDSESLKQDRELLENEKEVLKQMKTDLQGEAEEIE 3698
Query: 1916 KTTLNDELERKK-DDNNAIIKKA----------LDKRISDLKADAPQRDQEDDMNALIXX 1770
K L + ER++ ++ A I+K + + I D+K Q Q+ D
Sbjct: 3699 KIKLETQHERQRVEEMTAQIQKDREYLQKMNDNITREIHDIKYQEKQMKQKQDE------ 3752
Query: 1769 XXXXXXXXXXXXKIVSNLEVNILILHEELQKEKD----DKTALIKDLVAAEPGKR--TVN 1608
+ L+ I L +EL+KEK+ D++ L DL +E K+ +N
Sbjct: 3753 --------------LDQLKTEIQNLQQELEKEKEIIMKDRSEL--DLKQSELDKQQTNMN 3796
Query: 1607 EIVSHLESKSRSL-KEHFLREEEDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGE 1431
+I+ ++++ + L K+ EE+ +E+ + + +E+L+ K K
Sbjct: 3797 DIIETMKNERKQLDKDKEEMEEQKREIEKEKHDFDQGRNSLDEDLKMMKLQKQVF----- 3851
Query: 1430 GCEAEKQGLE--KTVLERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCE------AE 1275
E EK LE K LER A + + +EE++ E+ +TE + + AE
Sbjct: 3852 --EEEKNKLEQMKIELEREAGEIRKI----KEEIQNERQSLEKMTEELKREKESFTHLAE 3905
Query: 1274 KQGPEKTVLD-LEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAK--NASLTDNQEGH 1104
E+ +LD ++ SL LQ++ ++ + K+ D++ K N L +++ G
Sbjct: 3906 DTKKEQEILDEIKVANESLMAELQKEKSNFEEMRENISKQTEDVKNKKENLRLREDELG- 3964
Query: 1103 EAEIERKLEASNLTHNDELHKEKDDKKSIMNDLDRVKAEKQVLESKVSDLETTYSTLNNE 924
+L+A E+HK++ + I + +++E+ + V DL+ +L+ +
Sbjct: 3965 ------QLQA-------EIHKQQ---REIEKEKSNIESERAAIIKIVEDLQHKIISLDRD 4008
Query: 923 LQQKMDDNEAFLNERDGLEAVKQGLEK-----------------RVLDLEATIHDIEMKT 795
+ D EAF NER+ L+ +K LE+ RV ++ A I K
Sbjct: 4009 AESLKLDREAFENEREVLKQMKTELERETDEIEKIKLETQHDRQRVEEMTAQITKERDKI 4068
Query: 794 GKDDDYNEAEKQTLKKRISELEEAI-SILTDK--AKKLLKDINIWLSEVTELQEDLNKE- 627
+ + L ++ ++EE I SI +DK +K ++ SE+ +++EDL K+
Sbjct: 4069 NNLIEETNRKDMVLNEKNRDIEEKIKSIQSDKDMLEKEKHNLEKTRSELYKVKEDLEKQK 4128
Query: 626 -------SKEKQDLEKRVLELTSKLEK 567
KE++DLEK +T ++ +
Sbjct: 4129 ENTLAEIQKEREDLEKMNENITIEMHE 4155
Score = 89.7 bits (221), Expect = 9e-15
Identities = 114/525 (21%), Positives = 236/525 (44%), Gaps = 44/525 (8%)
Frame = -3
Query: 2027 DELLNEKDDK-----KCIVNDRNILEAAKQALE------YKVA-DLEAAKTTLNDELERK 1884
D +LNEK+ K I +D+++LE K LE YKV DLE K E++++
Sbjct: 5619 DMVLNEKNRDIEEKIKSIQSDKDMLEKEKHDLEKTRSELYKVKEDLEKQKENTLAEIQKE 5678
Query: 1883 KDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNI 1704
++D + + + + + ++K Q +Q+ D + L+ I
Sbjct: 5679 REDLEKM-NENITREMHEIKHQEEQMNQKQDE--------------------LDQLKTEI 5717
Query: 1703 LILHEELQKEKD----DKTALIKDLVAAEPGKR--TVNEIVSHLESKSRSL-KEHFLREE 1545
L +EL+KEK+ D++ L DL +E K+ +N+I+ ++++ + L K+ EE
Sbjct: 5718 QNLQQELEKEKEIIMKDRSQL--DLRQSELDKQQTNMNDIMETMKNERKQLDKDKEEMEE 5775
Query: 1544 EDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKT------VLER 1383
+ + +E+ N+ + +E+ +K K K E E K LE+ + E
Sbjct: 5776 QKQEMEKERDNMDQSRKSLDEDQKKMKLQKQMFEEEKNKLEQMKIELEREADEISKIKEE 5835
Query: 1382 RASNLDTMDAIHEEELRKE----------KVDKSALTEN---GEGCEAEKQGPEKTVLDL 1242
+ ++ + EE +R++ K +K L E E A+ Q + + ++
Sbjct: 5836 TQNKRQRLEKMTEELIREKESLAHLAEDTKTEKKILDEMKVANESSMADLQREKSILEEM 5895
Query: 1241 EPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKL-EASNL 1065
I L + + + ++ + L+K ++++ + + + + E+E + E N+
Sbjct: 5896 RENISKLKEYIDNEKEKSKLREDELKKLQTEVQKQQSKIDMEKTNIESERAAMIREKQNM 5955
Query: 1064 THNDELHKEKDD----KKSIMNDLDRVKAEKQVLESKVSDLETTYSTLNNELQQKMDDNE 897
EL K+ +D K I+ + + + ++++L V +L+ L + ++ D E
Sbjct: 5956 M--TELKKKSEDVEIQMKEILTEKELLHNDRKLLTRDVENLQQKLIDLERDSKRLKLDRE 6013
Query: 896 AFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAIS 717
AF NE++ ++ +K L+ + ++E I+++T D E ++K ++ I
Sbjct: 6014 AFENEKEAMKQMKTDLQIQADEIE----KIKLETQHDRQRVEEMAAQIQKERDKINNLIE 6069
Query: 716 ILTDKAKKLLKDINIWLSE-VTELQEDLNKESKEKQDLEKRVLEL 585
T++ +L + N + E + +Q D + KE+ +LEK EL
Sbjct: 6070 -ETNRKDMVLNEKNRDIEEKIKSIQSDKDMLEKERHNLEKTRSEL 6113
Score = 89.0 bits (219), Expect = 2e-14
Identities = 123/538 (22%), Positives = 234/538 (43%), Gaps = 24/538 (4%)
Frame = -3
Query: 2081 QALESKVSVFEAAIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLN 1902
Q +E + E A L E + + ++ I NDR E L+ + D+E + +
Sbjct: 2805 QIIEDERDKIEQIKAELQKEAKDTEKQRQDIENDRRNNEEMVIKLQNEKKDIETSTDRIR 2864
Query: 1901 DE-------LERKKDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXX 1743
DE +R + D + + K+ D + K + +D E + +
Sbjct: 2865 DEEANLRVLKQRLESDRDTLEKERFDLK----KTNTEMKDLEKQLESQNRQHEIQLAEIQ 2920
Query: 1742 XXXKIVSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKE 1563
+I+ L++ + E+L+KE+D D+ E E+ E +
Sbjct: 2921 KEREILEQLKLTLSKQKEDLEKERDCFEKEKADISLRE-------ELQEQSEREGIGKTR 2973
Query: 1562 HFLREEEDEVLE------RSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLE 1401
+++E DE+ + + N + K I E+E K + K+ L + E E +++ +E
Sbjct: 2974 VRIKKEMDELKQTRLNVVKELENNELQKQIIEDERDKIEQIKAELQKEAEDTEKQRRDIE 3033
Query: 1400 K---------TVLERRASNLDT-MDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTV 1251
K L+ +++T D I +EE E V K L + + E E+ EKT
Sbjct: 3034 KDRRNNEEMVIKLQNEKKDIETSTDRIRDEEANLE-VQKQRLESDRDTLEKERFDLEKTK 3092
Query: 1250 LDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIE-RKLEA 1074
++ +L L+ + + + ++K LE +L+ +E E E + + E
Sbjct: 3093 TEM----GNLKKQLESQIRQHEIQLVEIQKEREILEQLKINLSKQKEDLEKERDCFEKEK 3148
Query: 1073 SNLTHNDELHKEKDDKKSIMNDLDRVKAEKQVLESKVSDLETTYSTLNNELQQKMDDNEA 894
++++ +++L KE+ +++ I N R+K E LE +L NNELQ+K+ +
Sbjct: 3149 ADISLSEDL-KEQSEREGIDNTRTRIKQEMDELEKTRQNLAKEQE--NNELQKKIIE--- 3202
Query: 893 FLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISI 714
+ERD +E +K L+K EA +E+ +++ N E T K+ E E+++
Sbjct: 3203 --DERDKIEQIKAELKK-----EAEKTKLEL---QNERQNLEEAGTKLKKDRENVESLAE 3252
Query: 713 LTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLELTSKLEKCICGARDGL 540
+ + +L+++ I TE+Q N+ +K+ Q+ RVL K I GA++ L
Sbjct: 3253 ELGRKQVVLENMQI----ETEMQRKANESNKQMQE---RVLIELKKTVTDIAGAKEDL 3303
Score = 87.8 bits (216), Expect = 3e-14
Identities = 125/549 (22%), Positives = 249/549 (45%), Gaps = 43/549 (7%)
Frame = -3
Query: 2027 DELLNEKDDK-----KCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAI 1863
D +LNEK+ K I +D+++LE K LE ++L K ++LE++K++ A
Sbjct: 4079 DMVLNEKNRDIEEKIKSIQSDKDMLEKEKHNLEKTRSELYKVK----EDLEKQKENTLAE 4134
Query: 1862 IKKA---LDKRISDLKADAPQ-RDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILIL 1695
I+K L+K ++ + + + QE+ M + L+ I L
Sbjct: 4135 IQKEREDLEKMNENITIEMHEIKHQEEQMKQ--------------KQDELDQLKTEIQNL 4180
Query: 1694 HEELQKEKD----DKTALIKDLVAAEPGKR--TVNEIVSHLESKSRSL-KEHFLREEEDE 1536
+EL+KEK+ D++ L DL +E K+ +N+I+ ++++ + L K+ EE+ +
Sbjct: 4181 QQELEKEKEIIMKDRSEL--DLRQSELDKQQTNMNDIIETMKNERKLLDKDKEEMEEQKQ 4238
Query: 1535 VLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMD 1356
+E+ N+ +E+L+ K K + E E K L++ E R +T +
Sbjct: 4239 EMEKERDNMDQSIKSLDEDLKMMKLQKQVIEEEKNKLEQMKFELQREADEIRKIKEETQN 4298
Query: 1355 AIHEEELRKEKVDKSALTENGEGCE-AEKQGPEKTVLD-LEPTIPSLNDALQRDLDRVMA 1182
E EK+ K+ + E + AE EK +LD ++ S LQR+ +
Sbjct: 4299 ----ERQSLEKMTKALIKEREDLVHLAEYTKREKEMLDEMQVANKSSMADLQREKRILEE 4354
Query: 1181 EKQALEKRCSDLE---AKNASLTDNQEGHEAEIERK-----LEASNLTHN---------- 1056
++ + K+ D+E K+ D + + E++++ +E +N+
Sbjct: 4355 MRENISKQTEDIENEKEKSKLREDELKKLQTEVQKQQSEIDMEKTNIESERAVMIREKQN 4414
Query: 1055 --DELHKEKDD----KKSIMNDLDRVKAEKQVLESKVSDLETTYSTLNNELQQKMDDNEA 894
EL K+ +D K I+ + + ++ + +L+ + DL+ ++ + + D EA
Sbjct: 4415 MMTELKKKSEDVEIQMKEILTEKELLENDSNLLKKDMEDLKQKLMSIERDSESLKLDREA 4474
Query: 893 FLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISI 714
F NE++ L+ +K L+ + ++E I+++T D E + ++K E+ I +
Sbjct: 4475 FGNEKEVLKQMKTDLQIQADEIE----KIKLETQHDRQRVEEKTAQIQKDRDEINNLI-V 4529
Query: 713 LTDKAKKLLKDINIWLSE-VTELQEDLNKESKEKQDLEKRVLELTSKLEKCICGARDGLS 537
T++ +L +++ + E + +Q D + KE+ +LEK EL A++ L
Sbjct: 4530 ETNRKDMVLNEMDRDIEEKIKSIQSDKDMLEKERHNLEKTRSELAR--------AKENLE 4581
Query: 536 TIKEAWMSD 510
T +E D
Sbjct: 4582 TQREIERKD 4590
Score = 87.0 bits (214), Expect = 6e-14
Identities = 104/492 (21%), Positives = 228/492 (46%), Gaps = 21/492 (4%)
Frame = -3
Query: 2012 EKDDKKCIVNDRNI----LEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKALD 1845
EKD K N++N+ L A + L+ + A++E K L + ++R + + I K+
Sbjct: 2487 EKDRLKLQENEQNMQMSQLNAKQNELDERQAEMEKQKRELENVMDRLEKEKVEITKEK-- 2544
Query: 1844 KRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDD 1665
+R+++++ + +++ D+ + ++E + IL+ EL+K K+
Sbjct: 2545 QRVNEMQNEVKRKNASVDL------------IKQEVLREQDHIENSREILNRELEKIKEK 2592
Query: 1664 KTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNLAIMKAIRE 1485
KT L ++ A + K + + + L L ++E E E+ ++ + E
Sbjct: 2593 KTILAEEFEALDDKKEMIGKEMQRLGKMKAEL------QKEAEDTEKQRRDIDNDRRNNE 2646
Query: 1484 EELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHEEELRKEKVDKSAL 1305
E + K ++ K + + + E+ L + +R S+ DT++ +L K K + L
Sbjct: 2647 EMVIKLQNEKKDIETSTDRIRDEEANL-RVQKQRLESDRDTLEK-ERFDLEKTKTEMKDL 2704
Query: 1304 TENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASL 1125
+ + E Q + + +E I + L++ + +K+ LEK E + A +
Sbjct: 2705 EK-----QLESQSRQHEIQLVE--IQKEREILEQLKINLSKQKEDLEKERDCFEKEKADI 2757
Query: 1124 TDNQEGHEAEIERKLEASNLTHNDELHKEKDDKKSIMNDLDRVKAEKQVLESKVSDLETT 945
+ +E E + ++ + + E+ + + + +++ +L+ + +KQ++E + +E
Sbjct: 2758 SLREELEEQSEKEGIDKTRVRIKQEMDELEQTRLNVVKELENNELQKQIIEDERDKIE-- 2815
Query: 944 YSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTG--KDDDYN- 774
+ ELQ++ D E +R +E ++ E+ V+ L+ DIE T +D++ N
Sbjct: 2816 --QIKAELQKEAKDTE---KQRQDIENDRRNNEEMVIKLQNEKKDIETSTDRIRDEEANL 2870
Query: 773 -------EAEKQTLKKRISELEEAISILTDKAKKL---LKDINIWLSEVTELQEDLNK-- 630
E+++ TL+K +L++ + + D K+L + I L+E+ + +E L +
Sbjct: 2871 RVLKQRLESDRDTLEKERFDLKKTNTEMKDLEKQLESQNRQHEIQLAEIQKEREILEQLK 2930
Query: 629 --ESKEKQDLEK 600
SK+K+DLEK
Sbjct: 2931 LTLSKQKEDLEK 2942
Score = 85.9 bits (211), Expect = 1e-13
Identities = 115/526 (21%), Positives = 234/526 (44%), Gaps = 34/526 (6%)
Frame = -3
Query: 2042 IATLNDELLNEKDDKKCIV----NDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDD 1875
+A L+ EL KD+ + I +R+ +E + L ++ +E + D+ ++
Sbjct: 9570 MADLSRELQKAKDELEKIAYKTNKERHEVEQMQAELHSQIQAIEQQGQIMQDKQNHLEEK 9629
Query: 1874 NNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVN---- 1707
+I +K + +I + + Q +QE N L I N + N
Sbjct: 9630 ELSIQRKEEEIKIGNTEF---QIEQEHLNNVLEETNKRQHDLEVMRADIELNKQKNNKDF 9686
Query: 1706 --ILILHEELQKEKDD--------KTALIKDLVAAEPGKRTVNEIVSHLESK-SRSLKEH 1560
+ + EL+ EK D K + L E K + ++ L+SK ++ KE
Sbjct: 9687 ELLEKIRSELENEKYDLQIWTEQQKHLVEVQLQELEKEKERLEKMEIELQSKREQTEKEK 9746
Query: 1559 FLREEEDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLE--KTVLE 1386
+ ++R + + + + + + K+ L E E + E++ LE K +++
Sbjct: 9747 ADLNRVNAEIQREKQVIDKKRHMTNRAMEELETIKTELKERQEKIQTEQEKLEEEKLLVQ 9806
Query: 1385 RRASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDA-- 1212
A NL+ + + + K ++ ++ L E CE ++ E+ D+E I + +A
Sbjct: 9807 IEAENLNKVLEEIKRQQEKLEISEADLKVMKEQCENAREETERKKCDIEEQIQNNENAKH 9866
Query: 1211 -LQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEI--ERKL--EASN--LTHND 1053
L+++ + +KQ L+K+ DL+ + + +N E + + E+KL + +N L D
Sbjct: 9867 LLEQERKDIDKQKQELQKQADDLDMRMIAHRENVEMSKRSLDEEKKLLEQKANEILRQRD 9926
Query: 1052 ELHKEKDDKKSIMNDLDRVKAEKQVLESKVSDLETTYSTLNNEL---QQKMDDNEAFLNE 882
+L KEK+D N LD ++ E Q + +++ NE+ QQ+++++ +NE
Sbjct: 9927 DLEKEKEDMMKKWNKLDVLQNEMQNENKAMEEIKYELDGKRNEINKEQQRLEESLRAINE 9986
Query: 881 RDG-LEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTD 705
G LE ++ EK+ +E + +M E++ L + SELE+ + +
Sbjct: 9987 EKGDLEIMRADYEKQEQQIEEMRVEAKM-----------ERKELDQIKSELEKDKTEIDY 10035
Query: 704 KAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLELTSKLEK 567
+ KKL D N+ E +L++ ++ ++Q +E EL K+++
Sbjct: 10036 EWKKLNNDRNMIEKERNDLEKMKSELMTQRQQMEDERSELDQKIKE 10081
Score = 85.5 bits (210), Expect = 2e-13
Identities = 111/536 (20%), Positives = 235/536 (43%), Gaps = 46/536 (8%)
Frame = -3
Query: 2072 ESKVSVFEAAIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDEL 1893
E+K ++ E +E+ EK+ ++ R +E ++ +E + LE ++ ++ E
Sbjct: 11939 ETKANILEMKTKAEPEEIKKEKEKEEEEQEMRVKVEMERKEIEQIKSQLERVRSEMDHEQ 11998
Query: 1892 ERKKDDNNAII--KKALDKRISDLKADAPQRDQE-DDMNALIXXXXXXXXXXXXXXKIVS 1722
++ DD I K+ L+K S++ Q ++E +++ I +IV
Sbjct: 11999 KKLNDDKKMIEQEKEDLEKMKSEIMKQRQQMEEERSELDKKIKQTDLEKHDIENSKEIVE 12058
Query: 1721 NLEVNILILHEELQKEK-----------DDKTALIKDLVAAEPGKRTVNEIVSHLESKSR 1575
L V + E+Q +K D++ LI++ + + + E+ ++ +
Sbjct: 12059 KLMVEVEKQKHEIQFQKEELDIERQKIADEQDLLIQNKIEQQNENERIKEMDEEIKKERE 12118
Query: 1574 SLKEHFL-----REEEDEVLE---RSASNLAIMKAIREEELRKEKDGKSALVENGEGCEA 1419
+LKE + +EE + V+E R +L M E+ + + + L + E
Sbjct: 12119 TLKEMEVNLQKEKEEIESVIEETQRRKEDLEKMSTDINEQKQDLMNQRDLLKQ-----ER 12173
Query: 1418 EKQGLEKTVLERRASNLDTMDAI-----------HEEELRKEKVDKSALTENGEGCEAEK 1272
E+ + T L++R +T I +E+L++ + ++ E E
Sbjct: 12174 EEMNHKLTQLQQRIDEFETTSNILVTTKMEEKTEMDEKLQQAIKEYESIIEETNRKRTEL 12233
Query: 1271 QGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEI 1092
+ E + ++ D L+++ E++ L+K+ DLE + D +E + +
Sbjct: 12234 EEIEVDQSQQNKNVETMKDLLEKERKDTEKEREELQKQADDLEMQMIEHGDKEEMSKRSL 12293
Query: 1091 --ERKL--EASN--LTHNDELHKEKDDKKSIMNDLDRVKAEKQVLESKVSDLETTYSTLN 930
E+KL + +N L D+L KEK+D N+LD ++ E Q ++++ +++ T
Sbjct: 12294 DEEKKLLEQKANEILRQRDDLEKEKEDMMKKWNELDGLQKEIQNQKNEMEEIKCELETKR 12353
Query: 929 NELQQKMDDNEAFLN----ERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKD-DDYNEAE 765
E+ ++ E LN ER LE V+ EK + I ++ +KT + D+ ++
Sbjct: 12354 IEIIKEQKRLEESLNTVNEERQYLEIVRVDYEKH----QQQIEEMRVKTKMERDELDQLM 12409
Query: 764 KQTL--KKRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLE 603
+ L +K ++ I +L + ++ +++ ++ EL+ + K EK+DLE
Sbjct: 12410 AKMLMDRKENERSKDMIGLLKKEMEQTKFNLD---AQEEELKLEKQKIQNEKKDLE 12462
Score = 84.7 bits (208), Expect = 3e-13
Identities = 119/558 (21%), Positives = 246/558 (44%), Gaps = 48/558 (8%)
Frame = -3
Query: 2075 LESKVSVFEAAIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDE 1896
L+ + S + +ND + K+++K + D+ E KQ +E + D + ++ +L+++
Sbjct: 5324 LDLRQSELDKQQTNVNDIMETMKNERKQLDKDKEETEEQKQEMEKEKHDFDQSRKSLDED 5383
Query: 1895 LERKKDDNNAII--KKALDKRISDLKADAPQ--RDQEDDMNALIXXXXXXXXXXXXXXKI 1728
L+ K + K L++ +L+ +A + + +E+ N +
Sbjct: 5384 LKMMKLQKQVLEDEKSKLEQMKIELEREAVEIRKIKEEIQNERQNLEKMTEALKEEREDL 5443
Query: 1727 VSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLK--EHFL 1554
+ N +L E + ++++ E + +++ +E+K +L+ E L
Sbjct: 5444 AEETKKNNQVLDEMKVANESTLADILREKSNLEEMRENISKQTEDVENKKENLRLREDEL 5503
Query: 1553 REEEDEV------LERSASNL-----AIMKAIREEELR---KEKDGKSALVENGEGCEAE 1416
R+ + E+ +E+ N+ AI+K + + + + ++D +S ++ E E E
Sbjct: 5504 RQLQAEIHKQQREIEKEKINIESERAAIIKDVEDLQHKIICLDRDAESLKLDR-EAFENE 5562
Query: 1415 KQGLE--KTVLERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCEA----EKQGPEKT 1254
K+ L+ KT LER A ++ + E + +++V++ A + E E+ +
Sbjct: 5563 KEVLKQMKTELEREADEIEKIKL--ETQHDRQRVEEMAAQIQKDRDEINNLIEETNRKDM 5620
Query: 1253 VL-----DLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIE 1089
VL D+E I S+ Q D D + EK LEK S+L L +E AEI+
Sbjct: 5621 VLNEKNRDIEEKIKSI----QSDKDMLEKEKHDLEKTRSELYKVKEDLEKQKENTLAEIQ 5676
Query: 1088 RKLEA-----SNLT-------HNDELHKEKDD-----KKSIMNDLDRVKAEKQVLESKVS 960
++ E N+T H +E +K D K I N ++ EK+++ S
Sbjct: 5677 KEREDLEKMNENITREMHEIKHQEEQMNQKQDELDQLKTEIQNLQQELEKEKEIIMKDRS 5736
Query: 959 DLETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDD 780
L+ S L+ + D E NER L+ K+ +E++ ++E +++ D+
Sbjct: 5737 QLDLRQSELDKQQTNMNDIMETMKNERKQLDKDKEEMEEQKQEMEKERDNMDQSRKSLDE 5796
Query: 779 YNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEK 600
+ +K L+K++ E E+ +K +++ ++ E+++++E+ ++Q LEK
Sbjct: 5797 --DQKKMKLQKQMFEEEK------NKLEQMKIELEREADEISKIKEE---TQNKRQRLEK 5845
Query: 599 RVLELTSKLEKCICGARD 546
EL + E A D
Sbjct: 5846 MTEELIREKESLAHLAED 5863
Score = 84.0 bits (206), Expect = 5e-13
Identities = 103/498 (20%), Positives = 216/498 (43%), Gaps = 12/498 (2%)
Frame = -3
Query: 2075 LESKVSVFEAAIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDE 1896
L+ + S + +ND + K+++K + D+ E KQ +E + D + ++ +L+++
Sbjct: 4647 LDLRQSELDKQQTNMNDIMETMKNERKQLDKDKEETEEQKQEMEKEKHDFDQSRKSLDED 4706
Query: 1895 LERKKDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNL 1716
L+ K + K+ +++ S LK + ++E D + N
Sbjct: 4707 LKMMK-----LQKQVIEEEKSKLKQMKIELEREADEIRKVKEE-------------TQNE 4748
Query: 1715 EVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEED- 1539
+ E L+KE++D +E KR N+++ ++ + S LRE +
Sbjct: 4749 RQIFEKMTEALKKERED---------LSEDAKRK-NQVLDEMKVANESTLADILRERSNL 4798
Query: 1538 -EVLERSASNLAIMKAIREE-ELRKEKDGKSALVENGEGCEAEKQGLEKTVLER-RASNL 1368
E+ E + ++ +E+ LR+EK + + + E EK EK+ +ER RA+ +
Sbjct: 4799 QEMRENISKQTEDVENKKEKIRLREEKLKQLQAEIHKQQSETEK---EKSNIERERAAII 4855
Query: 1367 DTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRV 1188
++ + + + ++ D +L + E E EK+ ++ +LE +++++
Sbjct: 4856 KDVEDLQSKIISLDR-DAESLKLDREAFENEKEELKQMKTELEREAD--------EIEKI 4906
Query: 1187 MAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASNLTHNDELHKEKDDKKSIMND 1008
E Q +R ++ A +N+ + + +++ E H +KS+ +
Sbjct: 4907 KLETQHERQRVEEMTADFMETMNNERKQLNKNKEEMQEQKQEMEKERHDMDQSRKSLDKN 4966
Query: 1007 LDRVKAEKQVLESKVSDLETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDL 828
L +K +KQV+E + + LE L E + E NER LE + + L+K
Sbjct: 4967 LKMMKLQKQVIEEEKNKLEQMKIELEKEADEIRKIKEETQNERQRLEKMTEELKKEKESF 5026
Query: 827 EATIHDI--------EMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLLKDINI 672
D +MK + + +K+ K + E+ E IS T+ ++K + I +
Sbjct: 5027 THLAEDTKTEKKILDKMKVANESLMADLQKE--KSNLEEMRENISKQTEDSEKEKEKIRL 5084
Query: 671 WLSEVTELQEDLNKESKE 618
E+ +LQ +++K+ E
Sbjct: 5085 REDELEQLQAEIHKQQGE 5102
Score = 83.2 bits (204), Expect = 9e-13
Identities = 116/555 (20%), Positives = 242/555 (43%), Gaps = 19/555 (3%)
Frame = -3
Query: 1979 RNILEAAKQALEYKVADLEAAKTTLND---ELERKKDDNNAIIKKALDKRISDLKADAPQ 1809
R LE + L+Y ++ K L EL+R+ DD + +K ++R S K
Sbjct: 3455 RTALEVEMKELKYHKQAIQEEKNKLQQMKIELQREADDIKKLKEKTRNERQSLEKMAENL 3514
Query: 1808 RDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHE----ELQKEKDDKTALIKDL 1641
++DD+ L + + +LHE ++QKEK + + + +
Sbjct: 3515 EKEKDDLAHLAED--------------TKRKDDEMKVLHESALADIQKEKCNLEQMRESM 3560
Query: 1640 VAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNLAIMKAIREEE----LR 1473
NE++ E K L+E L++ + E+ R + + K+I E E +
Sbjct: 3561 FKQ-------NEMIDS-EKKKMILREDKLQQMQAEI-NRQQTEMDTKKSIIENERAAMTK 3611
Query: 1472 KEKDGKSALVENGEGCEAEKQGL--EKTVLERRASNLDTMDAIHEEELRKEKVDKSALTE 1299
K +D + L + E E + + + EK +LE L +++L + D +L +
Sbjct: 3612 KNQDLMTELTKQSEDVEIQMKEVLTEKELLESDRKLLKKDVENLQQKLLIIESDSESLKQ 3671
Query: 1298 NGEGCEAEKQGPEKTVLDLE---PTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNAS 1128
+ E E EK+ ++ DL+ I + Q + RV ++K L+ N +
Sbjct: 3672 DRELLENEKEVLKQMKTDLQGEAEEIEKIKLETQHERQRVEEMTAQIQKDREYLQKMNDN 3731
Query: 1127 LTDNQEGHEAEIERKLEASNLTHNDELHKEKDDKKSIMNDLDRVKAEKQVLESKVSDLET 948
+T +E H+ + + K DEL + K + +++ +L++ EK+++ S+L+
Sbjct: 3732 IT--REIHDIKYQEKQMKQK---QDELDQLKTEIQNLQQELEK---EKEIIMKDRSELDL 3783
Query: 947 TYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEM-KTGKDDDYN- 774
S L+ + D E NER L+ K+ +E++ ++E HD + + D+D
Sbjct: 3784 KQSELDKQQTNMNDIIETMKNERKQLDKDKEEMEEQKREIEKEKHDFDQGRNSLDEDLKM 3843
Query: 773 -EAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKR 597
+ +KQ ++ ++LE+ + I ++ ++ I + + E + +E K +++
Sbjct: 3844 MKLQKQVFEEEKNKLEQ-MKIELEREAGEIRKIKEEIQNERQSLEKMTEELKREKESFTH 3902
Query: 596 VLELTSKLEKCICGARDGLSTIKEAWMSDCMVPDNWVPFEDLVQGFSRKTSPLDITKTCD 417
+ E T K ++ + D + E+ M++ + FE++ + S++T D+ +
Sbjct: 3903 LAEDTKKEQEIL----DEIKVANESLMAELQKEKS--NFEEMRENISKQTE--DVKNKKE 3954
Query: 416 AVDISEDSTTNIQVD 372
+ + ED +Q +
Sbjct: 3955 NLRLREDELGQLQAE 3969
Score = 81.3 bits (199), Expect = 3e-12
Identities = 112/514 (21%), Positives = 217/514 (42%), Gaps = 22/514 (4%)
Frame = -3
Query: 2042 IATLNDELLNEKDDKKC-----------IVNDRNILEAAKQALEYKVADLEAAKTTLNDE 1896
I+ +++ NEK+ K + ++ ++ K +E + A + K + E
Sbjct: 4359 ISKQTEDIENEKEKSKLREDELKKLQTEVQKQQSEIDMEKTNIESERAVMIREKQNMMTE 4418
Query: 1895 LERKKDDNNAIIKKAL-DKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSN 1719
L++K +D +K+ L +K + + ++ ++D ED L+ +
Sbjct: 4419 LKKKSEDVEIQMKEILTEKELLENDSNLLKKDMEDLKQKLMSIERDSESLKLDREAFGNE 4478
Query: 1718 LEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEED 1539
EV + + +LQ + D+ + K + + ++ V E + ++ K R E +
Sbjct: 4479 KEV-LKQMKTDLQIQADE---IEKIKLETQHDRQRVEEKTAQIQ-KDRD-------EINN 4526
Query: 1538 EVLERSASNLAIMKAIR--EEELRKEKDGKSALVENGEGCEAEKQGLEKT--VLERRASN 1371
++E + ++ + + R EE+++ + K L E E+ LEKT L R N
Sbjct: 4527 LIVETNRKDMVLNEMDRDIEEKIKSIQSDKDML-------EKERHNLEKTRSELARAKEN 4579
Query: 1370 LDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDR 1191
L+T I +++ K K + S + E + + + + L+ I +L L+++ +
Sbjct: 4580 LETQREIERKDIEKMKKNISREMHEIKHQEEQMKQKQDELDQLKTEIQNLQQELEKEKEI 4639
Query: 1190 VMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIER--KLEASNLTHNDELHKEKDD---- 1029
+M + L+ R S+L+ + ++ D E + E ++ K + E+ KEK D
Sbjct: 4640 IMKARSQLDLRQSELDKQQTNMNDIMETMKNERKQLDKDKEETEEQKQEMEKEKHDFDQS 4699
Query: 1028 KKSIMNDLDRVKAEKQVLESKVSDLETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGL 849
+KS+ DL +K +KQV+E + S L+ L E + E NER E + + L
Sbjct: 4700 RKSLDEDLKMMKLQKQVIEEEKSKLKQMKIELEREADEIRKVKEETQNERQIFEKMTEAL 4759
Query: 848 EKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIW 669
+K DL D + K D+ A + TL DI
Sbjct: 4760 KKEREDLS---EDAKRKNQVLDEMKVANESTLA----------------------DI--- 4791
Query: 668 LSEVTELQEDLNKESKEKQDLEKRVLELTSKLEK 567
L E + LQE SK+ +D+E + ++ + EK
Sbjct: 4792 LRERSNLQEMRENISKQTEDVENKKEKIRLREEK 4825
Score = 80.9 bits (198), Expect = 4e-12
Identities = 119/523 (22%), Positives = 221/523 (42%), Gaps = 20/523 (3%)
Frame = -3
Query: 2075 LESKVSVFEAAIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDE 1896
L++ S E + +L E N +D+K + R+ + + A+ + DLE + E
Sbjct: 9246 LQNMKSNLERQLESLRHEKANVEDEKNALEKMRSESKEIQNAIRKEREDLENCWVEIEGE 9305
Query: 1895 LERKKDDNNAI------IKKALDKRISDLKADAPQRDQE--DDMNALIXXXXXXXXXXXX 1740
+R +++ + IKK +D + + + R+++ + M L+
Sbjct: 9306 KKRMEEETRRLEMHREEIKK-VDSELQKSRENIESREEKINNKMEELLQMKVEMGRTKEE 9364
Query: 1739 XXKIVSNLEVNILILHE---ELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSL 1569
K L+ + L E+Q++ +DK I D+ E + EI L+ +++ L
Sbjct: 9365 IEKESQRLQDATIDLENAKAEIQRQ-EDKFEDIIDIKIQEKER----EIKIQLDKETKRL 9419
Query: 1568 KEHFLREEEDEVLE-----RSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGL 1404
E + +D +E R + K + E+E ++ K K L + EKQ
Sbjct: 9420 SEEIELKVKDLEMEMADMKRQKQEIEDTKGLLEKEKQELKQEKKELEDQMMDLTREKQET 9479
Query: 1403 EKTVLERRASNLDTMDAIHEEELRKEKV--DKSALTENGEGCEAEKQGPEKTVLDLEPTI 1230
E+ A D E E+ KEK+ +KS + E +++ ++T + +
Sbjct: 9480 EEERNNLMALKNQLEDLRKENEIVKEKLTLEKSNIEEMQLKIFKQQRLNDQTREENKKE- 9538
Query: 1229 PSLNDALQRDLDRVMAEKQALEKRCSDL-EAKNASLTDNQEGHEAEIERKLEASNLTHND 1053
++L++ +KQ LE + + E KN ++E +A+ E LE N
Sbjct: 9539 ---KESLEQQRFETEQQKQMLEISTTKMMEEKNEMADLSRELQKAKDE--LEKIAYKTNK 9593
Query: 1052 ELHKEKDDKKSIMNDLDRVKAEKQVLESKVSDLETTYSTLNNELQQKMDDNEAFLNERDG 873
E H+ + + + + + ++ + Q+++ K + LE ++ + ++ N F E++
Sbjct: 9594 ERHEVEQMQAELHSQIQAIEQQGQIMQDKQNHLEEKELSIQRKEEEIKIGNTEFQIEQEH 9653
Query: 872 LEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKK 693
L V + KR DLE DIE+ K N + + L+K SELE
Sbjct: 9654 LNNVLEETNKRQHDLEVMRADIELNKQK----NNKDFELLEKIRSELENE---------- 9699
Query: 692 LLKDINIWLSEVTELQE-DLNKESKEKQDLEKRVLELTSKLEK 567
D+ IW + L E L + KEK+ LEK +EL SK E+
Sbjct: 9700 -KYDLQIWTEQQKHLVEVQLQELEKEKERLEKMEIELQSKREQ 9741
Score = 80.1 bits (196), Expect = 7e-12
Identities = 122/570 (21%), Positives = 236/570 (41%), Gaps = 68/570 (11%)
Frame = -3
Query: 2075 LESKVSVFEAAIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLE--AAKTTLN 1902
+E+K + L D+ + K+D+ D LE ++ L + DLE +
Sbjct: 9062 METKKRSLDRMSRELQDDKIRLKNDRDAYEKDMTHLELKREELVRETEDLERKILQQREQ 9121
Query: 1901 DELERKKDDNNA---------IIKK-----------------------ALDKRISDLKAD 1818
DE+ ++ +N I+KK AL + S+L+
Sbjct: 9122 DEMAKRDIENQTEALEVMKVDILKKRNEFAKEMENVHSERQKLLLLQGALQSQESELENR 9181
Query: 1817 APQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDKTALIKDLV 1638
+Q+ A + + + L EELQ+EK ++ + K+ +
Sbjct: 9182 VFMEEQKHLKQAKAETEECRKQLAEMSETVTTE-QNEYRKLIEELQREK-EQLEISKNQI 9239
Query: 1637 AAEPGKRTVNEIVSHLESKSRSLK-EHFLREEEDEVLERSAS-NLAIMKAIREEELRKEK 1464
E K+ + + S+LE + SL+ E E+E LE+ S + I AIR+E
Sbjct: 9240 EQE--KKDLQNMKSNLERQLESLRHEKANVEDEKNALEKMRSESKEIQNAIRKER----- 9292
Query: 1463 DGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHEEELRKEKVDKSALTENGEGC 1284
E+ E C E +G EK +E L+ +H EE++K + EN E
Sbjct: 9293 -------EDLENCWVEIEG-EKKRMEEETRRLE----MHREEIKKVDSELQKSRENIESR 9340
Query: 1283 EAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTD----N 1116
E + + +L ++ + + ++++ R+ LE ++++ + D
Sbjct: 9341 EEKINNKMEELLQMKVEMGRTKEEIEKESQRLQDATIDLENAKAEIQRQEDKFEDIIDIK 9400
Query: 1115 QEGHEAEIERKLEASNLTHNDELHKEKDDKKSIMNDLDRVKAE----KQVLESKVSDLET 948
+ E EI+ +L+ ++E+ + D + M D+ R K E K +LE + +L+
Sbjct: 9401 IQEKEREIKIQLDKETKRLSEEIELKVKDLEMEMADMKRQKQEIEDTKGLLEKEKQELKQ 9460
Query: 947 TYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLE---------KRVLDLE-ATIHDIEMK 798
L +++ + + ER+ L A+K LE K L LE + I ++++K
Sbjct: 9461 EKKELEDQMMDLTREKQETEEERNNLMALKNQLEDLRKENEIVKEKLTLEKSNIEEMQLK 9520
Query: 797 TGKDD-------DYNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQED 639
K + N+ EK++L+++ E E+ +L K++++ N ELQ+
Sbjct: 9521 IFKQQRLNDQTREENKKEKESLEQQRFETEQQKQMLEISTTKMMEEKNEMADLSRELQKA 9580
Query: 638 LN-------KESKEKQDLEKRVLELTSKLE 570
+ K +KE+ ++E+ EL S+++
Sbjct: 9581 KDELEKIAYKTNKERHEVEQMQAELHSQIQ 9610
Score = 79.3 bits (194), Expect = 1e-11
Identities = 93/521 (17%), Positives = 226/521 (43%), Gaps = 46/521 (8%)
Frame = -3
Query: 1991 IVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKALDKR--------- 1839
++N R++L+ ++ + +K L+ + ++ ++K+++ KK ++R
Sbjct: 11607 LMNQRDLLKQEREEINHKWTQLQQRIDEFDAQVSKQKEEDLTKQKKMEEERKSLEETKIK 11666
Query: 1838 ISDLKADAP--------QRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEEL 1683
I ++K ++++E+ M A + I S LE + E
Sbjct: 11667 IIEMKTKTEPEKIKKEKEKEEEEVMRAKVEMKKEELDQ------IKSQLERVRSEIDHEQ 11720
Query: 1682 QKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNLAI 1503
+K DDK + ++ E K + + +E + RS E+ +R+ E + S +
Sbjct: 11721 KKLNDDKKMIEQEKEDLEKMKSEIMKQRQQMEEE-RSELENKIRQTYIEKCDIENSKEIV 11779
Query: 1502 MKAIREEELRKEK----------------DGKSALVENGEGCEAEKQGLEKT--VLERRA 1377
K + E E +K + D + L++N + E + ++ V+++
Sbjct: 11780 QKLMVEVEEQKHEIQFQKEELDIERQKIADEQDLLIQNKSELQNENERIKNINEVIKKER 11839
Query: 1376 SNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDL 1197
L M+A L KEK + ++TE + + + + + + + S D L+++
Sbjct: 11840 ETLKEMEAY----LEKEKEEMKSITEETRRQKEDLEKMSTHINEQKQDLRSQRDLLEQER 11895
Query: 1196 DRVMAEKQALEKRCSDLEA-----------KNASLTDNQEGHEAEIERKLEASNLTHNDE 1050
+ + + + L++R + +A K + ++++ E LE +E
Sbjct: 11896 EEINHKWKQLQQRIDEFDAQVSKQKEEDLPKEKEMKEDRKSLEETKANILEMKTKAEPEE 11955
Query: 1049 LHKEKDDKKSIMNDLDRVKAEKQVLESKVSDLETTYSTLNNELQQKMDDNEAFLNERDGL 870
+ KEK+ ++ +V+ E++ +E S LE S +++E ++ DD + E++ L
Sbjct: 11956 IKKEKEKEEEEQEMRVKVEMERKEIEQIKSQLERVRSEMDHEQKKLNDDKKMIEQEKEDL 12015
Query: 869 EAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKL 690
E +K + K+ +E +++ K K D + + + K+ + +L + + +
Sbjct: 12016 EKMKSEIMKQRQQMEEERSELDKKI-KQTDLEKHDIENSKEIVEKLMVEVEKQKHEIQFQ 12074
Query: 689 LKDINIWLSEVTELQEDLNKESKEKQDLEKRVLELTSKLEK 567
++++I ++ + Q+ L + E+Q+ +R+ E+ +++K
Sbjct: 12075 KEELDIERQKIADEQDLLIQNKIEQQNENERIKEMDEEIKK 12115
Score = 78.6 bits (192), Expect = 2e-11
Identities = 134/578 (23%), Positives = 246/578 (42%), Gaps = 76/578 (13%)
Frame = -3
Query: 2072 ESKVSVFEAAIATLNDELLNEKDD---KKCIVNDR-NILEAAKQALEYKVADLEAAKTTL 1905
+ K+ + EA + + ++ N +++ KKC + ++ E AK LE + D++ K
Sbjct: 9823 QEKLEISEADLKVMKEQCENAREETERKKCDIEEQIQNNENAKHLLEQERKDIDKQK--- 9879
Query: 1904 NDELERKKDD----------NNAIIKKALD--KRISDLKADAPQRDQEDDMNALIXXXXX 1761
EL+++ DD N + K++LD K++ + KA+ R ++D +
Sbjct: 9880 -QELQKQADDLDMRMIAHRENVEMSKRSLDEEKKLLEQKANEILRQRDD-----LEKEKE 9933
Query: 1760 XXXXXXXXXKIVSNLEVNILILHEELQKEKDDKTALI-KDLVAAEPGKRTVNEIVSHLES 1584
++ N N EE++ E D K I K+ E R +NE LE
Sbjct: 9934 DMMKKWNKLDVLQNEMQNENKAMEEIKYELDGKRNEINKEQQRLEESLRAINEEKGDLEI 9993
Query: 1583 KSRSLKEHFLREEEDEV--------LERSASNLAIMKAIREEELRKEKDGKSALVENGEG 1428
++ + EE V L++ S L K + E +K + ++ + +
Sbjct: 9994 MRADYEKQEQQIEEMRVEAKMERKELDQIKSELEKDKTEIDYEWKKLNNDRNMIEKERND 10053
Query: 1427 CEAEKQGL--EKTVLERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKT 1254
E K L ++ +E S LD I E K+K++K+ E E+Q +
Sbjct: 10054 LEKMKSELMTQRQQMEDERSELD--QKIKEANTEKDKIEKNKEIVERLMAEVEEQRNDFK 10111
Query: 1253 VLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEG--HEAEIERKL 1080
+ E + N ++ EK L + ++L+ K+ + + +E +E E ++
Sbjct: 10112 LKKEELALERQN---------IVDEKYLLAQCETELQNKSEQIRNMEEAVKNERETLKET 10162
Query: 1079 EASNLTHNDELHKEKDDKKSIMNDLDRVK-----------AEKQVLESKVSDLETTYSTL 933
EA L ++K + KSI+ + R K +KQ L++K LE +
Sbjct: 10163 EA-------HLQRDKKEIKSIIEETSRQKEDLEKISTGMNVQKQELKNKKDTLEQEREEI 10215
Query: 932 NN---ELQQKMDDNEAFLN---ERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNE 771
N+ + QQ++D+ +A + E D K E++ L+ E IEMKT + +++E
Sbjct: 10216 NHKWTQFQQRIDEFDAQVRKQKEEDLTNQKKMEEERKCLE-EVNGKIIEMKTKAELEHHE 10274
Query: 770 A-----EKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEV----TEL---------- 648
E QTL+++I + +E +T K K +D++ SE+ TE+
Sbjct: 10275 INQKIEELQTLQEQIMKEKEKAEAMTIKLKMEREDLDQIKSELVREKTEVDHEQKKLNDD 10334
Query: 647 -------QEDLNKESKE----KQDLEKRVLELTSKLEK 567
+EDL K E KQ++EK EL +K+++
Sbjct: 10335 IKMIEQEKEDLEKMKSEIMTQKQEMEKERSELDNKIQQ 10372
Score = 77.0 bits (188), Expect = 6e-11
Identities = 108/541 (19%), Positives = 221/541 (40%), Gaps = 58/541 (10%)
Frame = -3
Query: 2042 IATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAI 1863
IA + D+LL EK+D +E K+ + + +E ++ LND+ E +N +
Sbjct: 13258 IADMKDQLLKEKED----------VETTKERINREKEHIEKMQSQLNDQKEEMDLENQKL 13307
Query: 1862 I---------KKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEV 1710
+ AL+K + DL+ + +++NAL+ E
Sbjct: 13308 LYMKTEIQVKTNALEKMMQDLQKE------RENVNALVIQHQ-------------KEREQ 13348
Query: 1709 NILILHEELQKEKDDKTALIKDLVAAEPGK-------RTVNEIVSHLESKSRSLKEHFLR 1551
+++ E +KEK + + + E K ++++ S L+++S L E+ ++
Sbjct: 13349 RDILIEENKRKEKHAEAEIQRQFEDIESVKVRLVTESNQIDKMNSELKTRSEEL-ENLIK 13407
Query: 1550 EEEDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASN 1371
+++ E + KA+ E++ E + KS ++N + EK + + L++ +
Sbjct: 13408 KQQKEFETKENEMQRERKAL--EKMNAELERKSTELKN----KIEKVTVWEADLQKEKNK 13461
Query: 1370 LDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDR 1191
+ + I E E + +K+ + + E ++ + + +LE L D + L R
Sbjct: 13462 TEELKNILEREKSELYQEKAQVQQQKHEMETIRKTMKSEMENLECLRNELEDEKKSMLSR 13521
Query: 1190 VMAEKQALEKRCSDLEAKNAS----------LTDNQEGHEAEIERKLEASNLTHNDELHK 1041
+ EK ++K ++++++ S L D E +++ +E N+ + +
Sbjct: 13522 LSMEKHEIDKLKTEIQSEKESIEEEKKTLKQLKDENESKRTQLDNTIEKMNMDKLS-IQR 13580
Query: 1040 EKDDKKSIMNDLDRVKAEK-----------------------------QVLESKVSDLET 948
EKD + I DL R KAEK + L S +D+E
Sbjct: 13581 EKDSLEEIKADLQR-KAEKLDEEMRKAVQITSQISQDAKILDDDREKEEELRSMRADIER 13639
Query: 947 TYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEA 768
L +++Q L+ K+ LEK + + D+E K N+
Sbjct: 13640 QAKILESDVQL--------------LQTEKEILEKSKTENDLLREDLE----KQRKRNDL 13681
Query: 767 EKQTLKKRISELEEAISILT---DKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKR 597
Q L+K LE+ I+ +T D L ++++ E+ + +L+++ KE DL +
Sbjct: 13682 TLQELRKEKMALEQMITDITKEKDAVASLQNEVSLKQHELKNKETELDEQRKEMDDLRMQ 13741
Query: 596 V 594
+
Sbjct: 13742 L 13742
Score = 75.5 bits (184), Expect = 2e-10
Identities = 117/561 (20%), Positives = 241/561 (42%), Gaps = 56/561 (9%)
Frame = -3
Query: 2081 QALESKVSVFEAAIATLNDELLNEK----DDKKCIVNDRNILEAAKQALEYKVADLEAAK 1914
Q + ++ + IA D L+ K ++ + I N +++ ++ L+ A LE K
Sbjct: 10402 QLQKEELDIERQKIADEQDLLIQNKSELQNENERIRNINEVIKKERETLKEMEAHLEKEK 10461
Query: 1913 T---TLNDELERKKDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXX 1743
++ +E R+K+D L+K +D+K ++ D+ L
Sbjct: 10462 EEMKSITEETRRQKED--------LEKMSTDIKEQNQDLMKQRDL--LEQEKEDINHEWT 10511
Query: 1742 XXXKIVSNLEVNILILHEE---LQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRS 1572
+ + + + EE QKE ++ +++ A +T E+ + K +
Sbjct: 10512 QLQQRIDEFDAQVSKQKEEDLTKQKEMKEERKSLEETKARIIEMKTKAELEDIKKEKEKE 10571
Query: 1571 LKEHFLR---EEEDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLE 1401
+E +R E + + L+R S L ++ + E +K D K + E EKQ LE
Sbjct: 10572 EEEEEMRVKVEMDGKELDRIKSELKRERSEIDHEQKKLNDDKKII-------EQEKQNLE 10624
Query: 1400 KTVLERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPT---I 1230
K ++ + + EE E K E + E K+ +K ++++E I
Sbjct: 10625 KM----KSEIMKQRQQMEEERSELENKIKQTYIEKCD-IENSKEIVQKLMVEVEEQKHEI 10679
Query: 1229 PSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQE--GHEAEIERKLEASNLTHN 1056
+ L + ++ E+ L + S+L+ +N + + E E E +++EA
Sbjct: 10680 QFQKEELDIERQKIADEQDLLIQNKSELQNENERIRNLNEIIKKERETLKEMEA------ 10733
Query: 1055 DELHKEKDDKKSIMNDLDRVKAEKQVLESKVSD-----------LETTYSTLNN---ELQ 918
L K+K++ KS+ + R+K + + + + V+ LE +N+ +LQ
Sbjct: 10734 -HLEKKKEEIKSVSEETRRLKEDLEKMSTDVNKQNKDLMNQRDLLEQEREEINHKWKQLQ 10792
Query: 917 QKMDDNEAFLNERDGLEAVKQ-GLEKRVLDLEAT-IHDIEMKTGKDDDYNEAEKQTLKKR 744
Q++D+ +A ++++ + K+ G+++ LE T + IEMKT + + + EK+ +
Sbjct: 10793 QRIDEFDAQVSKQKEQDLPKEKGMKEDRKSLEETKANVIEMKTKAEPEEIKKEKEKENEE 10852
Query: 743 ISELEEAISILTDKAKKLL------------------KDINIWLSEVTELQEDLNKES-- 624
E EE I ++ + +K L K +N ++ + + +EDL K
Sbjct: 10853 EEEEEEEIRVIVETERKELYQIKSELERVRSEIDHEQKKLNDYMKMIEQEKEDLEKMKSE 10912
Query: 623 --KEKQDLEKRVLELTSKLEK 567
K++Q +E+ EL +K+++
Sbjct: 10913 IMKQRQQMEEERSELDNKIQQ 10933
Score = 75.1 bits (183), Expect = 2e-10
Identities = 111/513 (21%), Positives = 212/513 (41%), Gaps = 67/513 (13%)
Frame = -3
Query: 1904 NDELERKKDD-NNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKI 1728
ND +E+ ++D NNA+ K +D+ D++ QE A++ I
Sbjct: 1457 NDRVEQMREDVNNAL--KDIDQAKEDIQRQREVIAQEKVQPAIVATKSSEYAKTEEPGAI 1514
Query: 1727 VSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLRE 1548
S + L L +QKE+ + K+++ E K +N+I +++ +E ++
Sbjct: 1515 KS-YRASDLELSASIQKERQELEHY-KEIILKE--KHELNKIKEDVKAVKNDAEERMIKL 1570
Query: 1547 EEDEVLERSASNLAIMKAIREEELRKEKD--GKSALVENGEGCEAEKQGL---------E 1401
E+E E +++ R+ + KEK+ G A+ + KQ L E
Sbjct: 1571 HEEEK-EMKTKRVSLQNWERQLQTEKEKNQKGLDAIWNENQQLNERKQQLDIKELHLQSE 1629
Query: 1400 KTVLERR-------------------ASNLDTMDAIHEEELRKEKVDKSALTENGEGCEA 1278
K+ LE + AS D +I E + +++ ++ + C
Sbjct: 1630 KSKLEYKKPLEIKQVDAQVQTELMEDASEYDMALSIEELDKQRQFLEYFKQELLAQKCTM 1689
Query: 1277 EKQGPE-------------------KTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRC 1155
E+Q E +T D+E + L++ D + K ++K
Sbjct: 1690 ERQMAEIELSRDELSLREATLQTATQTTADMELQLELQKQELEQTKDEMERTKLEVQKGW 1749
Query: 1154 SDLEAKNASLTDNQEGHEAEIERKLEASNLTHND-ELHK---EKDDKKSIMNDLDRVKAE 987
DL+ + A + +E E+E+ + N D E K E D K ++ + + ++A+
Sbjct: 1750 VDLQTQIAESREKEEMVRIELEKARDVLNRIRQDVETEKQTMEADLKFTLAKEFENLEAQ 1809
Query: 986 KQVLESKVSDLETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDI 807
++++E + LE L E +ER +E + L++ +LE HD+
Sbjct: 1810 RKMMEDEKRALENMKYELQRESGYIERSKHNMHDERQNMENWAEKLKQEWEELEKKRHDM 1869
Query: 806 EM------KTGKD-DDYNEAEKQTLK--KRISELEEAISILTDKAKKLLKD----INIWL 666
+ + KD ++ E + TL K S++ E IS L + K +++ I I
Sbjct: 1870 QQLQTERSREIKDLENLRELNELTLNQIKTKSDVLEKISELNSQQKDEIENEKSKIKIRE 1929
Query: 665 SEVTELQEDLNKESKEKQDLEKRVLELTSKLEK 567
++ ++Q DLN++ KE QD++ V S+L+K
Sbjct: 1930 YDLQQMQTDLNRQQKEMQDIQNAVFMEKSELKK 1962
Score = 73.6 bits (179), Expect = 7e-10
Identities = 118/540 (21%), Positives = 235/540 (43%), Gaps = 37/540 (6%)
Frame = -3
Query: 2075 LESKVSVFEAAIATLN-DELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLND 1899
LE + FE A ++ E L E+ +K+ I D+ + ++ E + L K N+
Sbjct: 2743 LEKERDCFEKEKADISLREELEEQSEKEGI--DKTRVRIKQEMDELEQTRLNVVKELENN 2800
Query: 1898 ELERK--KDDNNAI--IKKALDKRISDLKADAPQRDQEDDMN---ALIXXXXXXXXXXXX 1740
EL+++ +D+ + I IK L K D + ++D E+D ++
Sbjct: 2801 ELQKQIIEDERDKIEQIKAELQKEAKD--TEKQRQDIENDRRNNEEMVIKLQNEKKDIET 2858
Query: 1739 XXKIVSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEH 1560
+ + E N+ +L + L+ ++D L K+ + + ++ LES++R +
Sbjct: 2859 STDRIRDEEANLRVLKQRLESDRD---TLEKERFDLKKTNTEMKDLEKQLESQNRQHEIQ 2915
Query: 1559 FLR-EEEDEVLERSASNLAIMKAIREEE---LRKEKDGKSALVENGEGCEAEKQGLEKTV 1392
++E E+LE+ L+ K E+E KEK S E E ++E++G+ KT
Sbjct: 2916 LAEIQKEREILEQLKLTLSKQKEDLEKERDCFEKEKADISLREELQE--QSEREGIGKT- 2972
Query: 1391 LERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDA 1212
R MD EL++ +++ EN E +KQ
Sbjct: 2973 ---RVRIKKEMD-----ELKQTRLNVVKELENNE---LQKQ------------------I 3003
Query: 1211 LQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASNLTHNDELHKEKD 1032
++ + D++ K L+K D E + + ++ +E E+ KL+ + +D
Sbjct: 3004 IEDERDKIEQIKAELQKEAEDTEKQRRDIEKDRRNNE-EMVIKLQNEKKDIETSTDRIRD 3062
Query: 1031 DKKSIMNDLDRVKAEKQVLESKVSDLETTYSTLNN---ELQQKMDDNEAFL----NERDG 873
++ ++ R+++++ LE + DLE T + + N +L+ ++ +E L ER+
Sbjct: 3063 EEANLEVQKQRLESDRDTLEKERFDLEKTKTEMGNLKKQLESQIRQHEIQLVEIQKEREI 3122
Query: 872 LEAVKQGLEKRVLDLEATIHDIEMKTG----KDDDYNEAEKQ-------TLKKRISELEE 726
LE +K L K+ DLE E + +D ++E++ +K+ + ELE+
Sbjct: 3123 LEQLKINLSKQKEDLEKERDCFEKEKADISLSEDLKEQSEREGIDNTRTRIKQEMDELEK 3182
Query: 725 AISIL------TDKAKKLLKDINIWLSEV-TELQEDLNKESKEKQDLEKRVLELTSKLEK 567
L + KK+++D + ++ EL+++ K E Q+ + + E +KL+K
Sbjct: 3183 TRQNLAKEQENNELQKKIIEDERDKIEQIKAELKKEAEKTKLELQNERQNLEEAGTKLKK 3242
Score = 73.2 bits (178), Expect = 9e-10
Identities = 128/570 (22%), Positives = 246/570 (43%), Gaps = 69/570 (12%)
Frame = -3
Query: 2072 ESKVSVFEAAIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDEL 1893
+ ++ + I L EL EK+ I+ DR+ L+ + ++L+ +T +ND +
Sbjct: 4167 QDELDQLKTEIQNLQQELEKEKE---IIMKDRS-------ELDLRQSELDKQQTNMNDII 4216
Query: 1892 ERKKDDNNAIIKKALDKRISDLKADAPQRDQE-DDMNALIXXXXXXXXXXXXXXKIVSNL 1716
E K++ +K LDK +++ + ++E D+M+ I +++
Sbjct: 4217 ETMKNE-----RKLLDKDKEEMEEQKQEMEKERDNMDQSIKSLDEDLKMMKLQKQVIEEE 4271
Query: 1715 EVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRS----LKEHFLRE 1548
+ + + ELQ+E D+ I+ + +R E ++ K R L E+ RE
Sbjct: 4272 KNKLEQMKFELQREADE----IRKIKEETQNERQSLEKMTKALIKEREDLVHLAEYTKRE 4327
Query: 1547 EE--DEVLERSASNLA-------IMKAIRE------EELRKEKDGKSALVENGEG---CE 1422
+E DE+ + S++A I++ +RE E++ EK+ KS L E+ E
Sbjct: 4328 KEMLDEMQVANKSSMADLQREKRILEEMRENISKQTEDIENEKE-KSKLREDELKKLQTE 4386
Query: 1421 AEKQ----GLEKTVLERRASNLDTMDAIHEEELRKEKVD-----KSALTENGEGCEAEKQ 1269
+KQ +EKT +E + + EL+K+ D K LTE E E +
Sbjct: 4387 VQKQQSEIDMEKTNIESERAVMIREKQNMMTELKKKSEDVEIQMKEILTEK-ELLENDSN 4445
Query: 1268 GPEKTVLDLEPTIPSL---NDALQRDLDRVMAEKQALEKRCSDLE--AKNASLTDNQEGH 1104
+K + DL+ + S+ +++L+ D + EK+ L++ +DL+ A + H
Sbjct: 4446 LLKKDMEDLKQKLMSIERDSESLKLDREAFGNEKEVLKQMKTDLQIQADEIEKIKLETQH 4505
Query: 1103 EAEIERKLEASNLTHNDELHK---EKDDKKSIMNDLDR--------VKAEKQVLESKVSD 957
+ + + A DE++ E + K ++N++DR ++++K +LE + +
Sbjct: 4506 DRQRVEEKTAQIQKDRDEINNLIVETNRKDMVLNEMDRDIEEKIKSIQSDKDMLEKERHN 4565
Query: 956 LETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDY 777
LE T S L + E ER +E +K+ + + + +++ H E K D+
Sbjct: 4566 LEKTRSELARAKENLETQREI---ERKDIEKMKKNISREMHEIK---HQEEQMKQKQDEL 4619
Query: 776 N-------------EAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLS--------E 660
+ E EK+ + K S+L+ S L DK + + DI + +
Sbjct: 4620 DQLKTEIQNLQQELEKEKEIIMKARSQLDLRQSEL-DKQQTNMNDIMETMKNERKQLDKD 4678
Query: 659 VTELQEDLNKESKEKQDLEKRVLELTSKLE 570
E +E + KEK D ++ L L+
Sbjct: 4679 KEETEEQKQEMEKEKHDFDQSRKSLDEDLK 4708
Score = 73.2 bits (178), Expect = 9e-10
Identities = 114/578 (19%), Positives = 242/578 (41%), Gaps = 91/578 (15%)
Frame = -3
Query: 2045 AIATLNDELLNEKDDKKCIVND----RNILEAAKQALEYKVADLEAAKTTLNDELERKKD 1878
++ + +EL EK+ + D + IL+ K A E +ADL+ K+ L + E
Sbjct: 6298 SLEKMTEELKKEKESFTHLAEDTKKEQEILDKVKVANESLMADLQKEKSNLEEMRENISK 6357
Query: 1877 DNNAIIKKALDKRISD-----LKADAPQRDQE-------------------DDMNALIXX 1770
+ K + R+ + L+A+ ++ +E +D+ I
Sbjct: 6358 QTEDVENKKENLRLREDELWQLQAEIYKQQREIEKEKINIESERAAIIKNVEDLQHKIIS 6417
Query: 1769 XXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSH- 1593
+ N + + EL++E D+ + K + + ++ V E+ +
Sbjct: 6418 LDRDSESLKLDREAFENEREVLKQMKTELEREADE---IEKIKLETQHERQRVEEMTADF 6474
Query: 1592 ---LESKSRSL-KEHFLREEEDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGC 1425
+ ++ + L K + EE+ + +E+ ++ + +E+L+ K K L E
Sbjct: 6475 METMNNERKQLDKNKVMIEEQKQEMEKKRDDMDQSRKSLDEDLKMMKAQKQVLEEEKNKL 6534
Query: 1424 EAEKQGLE---------KTVLERRASNLDTM-DAIHEE------ELRKEKVDKSALTENG 1293
E K GLE K + NL+ M +A+ EE E++++ +
Sbjct: 6535 EQMKIGLEREADEISKIKEETQNERQNLEKMANALKEEREYLAEEIKRKNQVLDKIKVAN 6594
Query: 1292 EGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQ 1113
E A+ Q ++ + ++ I + ++ + ++ + L+K ++++ + + + +
Sbjct: 6595 ESTLADLQKEKRILEEMRENISKQIEDIENEKEKSKLREDELKKLQTEVQKQQSEIDMEK 6654
Query: 1112 EGHEAEIERKL-EASNLTHNDELHKEKDD----KKSIMNDLDRVKAEKQVLESKVSDLET 948
E+E + E N+ EL K+ +D K I+ + + + ++ +L+ V DL+
Sbjct: 6655 TNIESERAAMIREKQNMM--TELKKKSEDVEMQMKEILTEKELLHNDRNLLKKDVEDLQQ 6712
Query: 947 TYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLE----ATIHD---IEMKTGK 789
++ + + D EAF NE++ ++ +K L+ + ++E T H+ +E KT +
Sbjct: 6713 KLMSIERDSESLKLDKEAFENEKEAMKQMKTDLQIQADEIEKIKLETHHERQRVEEKTAQ 6772
Query: 788 ----------------------DDDYNE--AEKQTLKKRISELEEAISILTDKAKKLLKD 681
D+ Y E EK+ ++ S+LE+A S + K K+
Sbjct: 6773 IQKEREEINTLVEEIKKKRDIIDESYTEIRKEKEAIESDRSDLEKAKS----QTFKQNKN 6828
Query: 680 INIWLSEVTELQEDLNKESKE------KQDLEKRVLEL 585
I I L+E+ + + L K SKE K + EK+ ++L
Sbjct: 6829 IEIALAEIQQKRNALEKMSKEISRDRMKLEDEKKEIQL 6866
Score = 73.2 bits (178), Expect = 9e-10
Identities = 101/486 (20%), Positives = 210/486 (43%), Gaps = 13/486 (2%)
Frame = -3
Query: 2036 TLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIK 1857
TL + N + I N+ L + + L D+ L + E + N +++
Sbjct: 7087 TLEEMRANISKQVETITNENKSLSSRESELAKLQEDI------LQQQQEMDELKNTIMME 7140
Query: 1856 KA-LDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQ 1680
LD+R SD+ D Q++ +D M+ ++N+E L + + +
Sbjct: 7141 MCQLDQRQSDI--DLLQKEVDDLMD--------------FTKTEMANVERERLEVLAQTR 7184
Query: 1679 KEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEV-LERSASNLAI 1503
K D +L + A E + +NE +E + L ++ ++D++ ++R NL +
Sbjct: 7185 NIKSDMVSLKMEKEACEQLRLKLNEEKDLIEKERELLTKNLDHTDKDKMDMKRELENLKV 7244
Query: 1502 MKAIREEELRKEKDGKSALVENGEGCE--AEKQGLEKTVLERRASN----LDTMDAIHEE 1341
K + E ++ + K +L G + +EK E+ ++E A+ LD + E
Sbjct: 7245 EKETIKNEKKELEKMKISLQRKAIGFKEFSEKTKDERPIVEEMAAQFTRQLDISERPAEG 7304
Query: 1340 ELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEK 1161
+ +E++D++ + EKT DL+ T +N D + + ++ L K
Sbjct: 7305 KFIEERLDQTEKKRRKTYYTEDLFQEEKT--DLQKTKEEIN----YDREEIYRQRTELNK 7358
Query: 1160 RCSDLEAKNASLTDNQEGHEAEIERKLEASNLTHNDELHKEKDDKKSIMNDLDRVKAEKQ 981
E E +++ SNL + + KEK+ + N+LD+++AE
Sbjct: 7359 -------------------EKETLKQMHTSNLKEIENIEKEKEKIQRTWNELDQIRAE-- 7397
Query: 980 VLESKVSDLETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEM 801
L++K D++ T + + E + D E NE+D L+ ++ ++K + +L+ E
Sbjct: 7398 -LQNKQRDMDDTTNIMMKEKAELARDLENLQNEKDELQKSRENIQKLMKELQ------EE 7450
Query: 800 KTGKDDDYNEAEKQ---TLKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQ--EDL 636
+ + N+ +Q +K + L+E + + + + L+ D I ++ +LQ +D+
Sbjct: 7451 RLKTSEALNKERQQFTEEIKLKNDSLDEIQAEIDRQKRALVTDKEIITKQMMDLQKTQDV 7510
Query: 635 NKESKE 618
++S E
Sbjct: 7511 RRQSDE 7516
Score = 72.4 bits (176), Expect = 2e-09
Identities = 119/603 (19%), Positives = 247/603 (40%), Gaps = 64/603 (10%)
Frame = -3
Query: 2042 IATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAI 1863
+ L E+ ++ K ++++ I ++ Q L + + L E+E K D
Sbjct: 8655 VRNLKGEMERRMEESKVEIDEKEIFKSEIQRLIQDIGQIRENLGGLKTEIENTKRD---- 8710
Query: 1862 IKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEEL 1683
K L+K ++L + Q+++E L + ++E++ ++ E+
Sbjct: 8711 -KSNLEKMKAEL--EEKQQEEESMREILQKEKEELEQLKKDINREKEDIEISRELVESEI 8767
Query: 1682 -----------QKEKDDKTALIKDLVAAEPGKRTVNEIVSHLES----------KSRSLK 1566
QK K++ + ++L+ + +N V HL K ++
Sbjct: 8768 YEGEVKGFTDVQKYKEELQIVTEELLTKKRNLEQLNSDVQHLMQTLEEVDIQYIKKKAEL 8827
Query: 1565 EHFLRE--EEDEVLERSASNL--------------AIMKAIREEELRKEKDGKSALVENG 1434
EH E + +++LE+ L +++I E L+K +D + +
Sbjct: 8828 EHITSEIQKREQILEKQKKKLEENGWIIEEIEMMKVTLESINMEILQKRED----MEKEK 8883
Query: 1433 EGCEAEKQGLE--KTVLERRASNLDT--MDAIHEEELRKEKVDKSALTENGEGCEAEKQG 1266
E EKQ E + L+R+ +++ I E++ K K+D E E E +
Sbjct: 8884 ENLRREKQETELFRGELQRQRDEVESSRQALIMEKDQFKLKIDHQR-NEMSAAFEKEHKR 8942
Query: 1265 PEKTVLDLE----PTIPSLNDA------LQRDLDRVMAEKQALEKRCSDLEAKNASLTDN 1116
E DLE SLNDA LQ+ + + EK+ +E+ ++ + +
Sbjct: 8943 LENMENDLENQRAKLAESLNDAAKMEQKLQQMKNELNKEKEQVEEMKQMVKTERVKIEQE 9002
Query: 1115 QE-----------GHEAEIERKLEASNLTHNDELHKEKDDKKSIMNDLD-RVKAEKQVLE 972
+E GHE ++++K E + D+L ++ + + + DL +++ ++Q +E
Sbjct: 9003 KEEMRKQTQEIEDGHE-KLQKKTEIA-----DKLLQDANSESDRLKDLSMKLQMQRQDIE 9056
Query: 971 SKVSDLETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTG 792
+++ET +L+ ++ DD N+RD E LE + +L D+E K
Sbjct: 9057 KTNTEMETKKRSLDRMSRELQDDKIRLKNDRDAYEKDMTHLELKREELVRETEDLERKIL 9116
Query: 791 KDDDYNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQ 612
+ + +E K+ ++ + LE + K + K++ SE +L ++
Sbjct: 9117 QQREQDEMAKRDIENQTEALEVMKVDILKKRNEFAKEMENVHSERQKLLLLQGALQSQES 9176
Query: 611 DLEKRV-LELTSKLEKCICGARDGLSTIKEAWMSDCMVPDNWVPFEDLVQGFSRKTSPLD 435
+LE RV +E L++ + + E MS+ + + + L++ R+ L+
Sbjct: 9177 ELENRVFMEEQKHLKQAKAETEECRKQLAE--MSETVTTEQ-NEYRKLIEELQREKEQLE 9233
Query: 434 ITK 426
I+K
Sbjct: 9234 ISK 9236
Score = 71.6 bits (174), Expect = 3e-09
Identities = 103/494 (20%), Positives = 209/494 (42%), Gaps = 8/494 (1%)
Frame = -3
Query: 2042 IATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLND---ELERKKDDN 1872
I ++ +E +K+D + I N+ KQ L+ K LE + +N + +++ D+
Sbjct: 10173 IKSIIEETSRQKEDLEKISTGMNV---QKQELKNKKDTLEQEREEINHKWTQFQQRIDEF 10229
Query: 1871 NAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILH 1692
+A ++K ++ +++ K +R +++N I ++ + H
Sbjct: 10230 DAQVRKQKEEDLTNQKKMEEERKCLEEVNGKII-----------------EMKTKAELEH 10272
Query: 1691 EELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASN 1512
E+ ++ I++L +T+ E + + K+ ++ E ED L++ S
Sbjct: 10273 HEINQK-------IEEL-------QTLQEQIMKEKEKAEAMTIKLKMERED--LDQIKSE 10316
Query: 1511 LAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGL--EKTVLERRASNLDTMDAIHEEE 1338
L K + E +K D + + E E K + +K +E+ S LD + I + +
Sbjct: 10317 LVREKTEVDHEQKKLNDDIKMIEQEKEDLEKMKSEIMTQKQEMEKERSELD--NKIQQTD 10374
Query: 1337 LRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKR 1158
L K ++KS E E+Q E I + L + ++ E+ L +
Sbjct: 10375 LEKHDIEKSKEIVEKLMFEVEEQRHE---------IQLQKEELDIERQKIADEQDLLIQN 10425
Query: 1157 CSDLEAKNASLTDNQE--GHEAEIERKLEASNLTHNDELHKEKDDKKSIMNDLDRVKAEK 984
S+L+ +N + + E E E +++EA L KEK++ KSI + R +K
Sbjct: 10426 KSELQNENERIRNINEVIKKERETLKEMEA-------HLEKEKEEMKSITEETRR---QK 10475
Query: 983 QVLESKVSDLETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIE 804
+ LE +D++ + N+ + +RD LE K+ + L+ I + +
Sbjct: 10476 EDLEKMSTDIK--------------EQNQDLMKQRDLLEQEKEDINHEWTQLQQRIDEFD 10521
Query: 803 MKTGKDDDYNEAEKQTLKKRISELEEA-ISILTDKAKKLLKDINIWLSEVTELQEDLNKE 627
+ K + + +++ +K+ LEE I+ K K L+DI + E +E K
Sbjct: 10522 AQVSKQKEEDLTKQKEMKEERKSLEETKARIIEMKTKAELEDIKKEKEKEEEEEEMRVKV 10581
Query: 626 SKEKQDLEKRVLEL 585
+ ++L++ EL
Sbjct: 10582 EMDGKELDRIKSEL 10595
Score = 71.6 bits (174), Expect = 3e-09
Identities = 112/532 (21%), Positives = 220/532 (41%), Gaps = 62/532 (11%)
Frame = -3
Query: 1982 DRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKAL--------DKRISDL 1827
D+ ++ K +LE ADL+ L++E+ + + I + A ++ + +
Sbjct: 13574 DKLSIQREKDSLEEIKADLQRKAEKLDEEMRKAVQITSQISQDAKILDDDREKEEELRSM 13633
Query: 1826 KADAPQRDQ--EDDMNALIXXXXXXXXXXXXXXKIVSNLEV----NILILHEELQKEKDD 1665
+AD ++ + E D+ L + +LE N L L +EL+KEK
Sbjct: 13634 RADIERQAKILESDVQLLQTEKEILEKSKTENDLLREDLEKQRKRNDLTL-QELRKEKMA 13692
Query: 1664 KTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVLE--RSASNLAIMKAI 1491
+I D+ + + V+ L+++ SLK+H L+ +E E+ E + +L + +
Sbjct: 13693 LEQMITDITKEK-------DAVASLQNEV-SLKQHELKNKETELDEQRKEMDDLRMQLEM 13744
Query: 1490 REEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTM---------------D 1356
R+ K++ + + + ++ + E R D + D
Sbjct: 13745 RQNSTNKQQQEVDVFIVENMKMRNDLESMKTLLDEERRQLQDNIKTFEDQKNVLHPSKTD 13804
Query: 1355 AIHE-EELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLN---DALQRDLDRV 1188
A+ + +EL K D E+ E E K ++ + + SLN + ++++
Sbjct: 13805 AVQQTDELEKFTTDIKTEKEHVEKEREEIDVLNKEIIKSKEELQSLNLEIEMFKQEIAGK 13864
Query: 1187 MAEKQALEKRCSDLEA------------KNASLTDNQEGHEAEIERKL-----EASNLTH 1059
A+ ++LE+ +DL A K ++ D ++ E E++ L E L +
Sbjct: 13865 RAQIESLEQLRADLLAGADDIKTLVQTEKQMAIEDTEKKTEVELQMNLQKQKNELEELRN 13924
Query: 1058 NDELHKEKDDKKSIMNDLDR---------VKAEKQVLESKVSDLETTYSTLNNELQQKMD 906
E K + + + IM D + +K+E+ VLE + S+L LN ++Q++ +
Sbjct: 13925 TIEAEKHQVENRKIMLDKQQKEVEDIMTVIKSERDVLEKEKSELNKLSHVLNEKVQREQE 13984
Query: 905 DNEAFLN-ERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELE 729
+ E L ERD +E K+ +E +EKQ++++ +EL
Sbjct: 13985 ELERLLEKERDDIENCKKIIE-------------------------SEKQSIERERAEL- 14018
Query: 728 EAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLELTSKL 573
K+L +++ + E T LQ+D N KEK+ LE T ++
Sbjct: 14019 ----------KRLKEEVEVQ-HERTLLQQDKNMIQKEKEHLEGEKARTTEEI 14059
Score = 70.1 bits (170), Expect = 7e-09
Identities = 116/533 (21%), Positives = 227/533 (42%), Gaps = 17/533 (3%)
Frame = -3
Query: 2075 LESKVSVFEAAIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDE 1896
L+ + S + +ND + K+++K + D+ +E KQ +E + +++ ++ +L+++
Sbjct: 5738 LDLRQSELDKQQTNMNDIMETMKNERKQLDKDKEEMEEQKQEMEKERDNMDQSRKSLDED 5797
Query: 1895 LERKKDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNL 1716
++ K + K+ ++ + L+ + ++E D + I N
Sbjct: 5798 QKKMK-----LQKQMFEEEKNKLEQMKIELEREADEISKIKEE-------------TQNK 5839
Query: 1715 EVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDE 1536
+ + EEL +EK+ L +D + K+ ++E+ ES L + E
Sbjct: 5840 RQRLEKMTEELIREKESLAHLAED---TKTEKKILDEMKVANESSMADL------QREKS 5890
Query: 1535 VLERSASNLAIMKAIREEELRKEKDGKSAL--VENGEGCEAEKQGLEKTVLERRASNLDT 1362
+LE N++ +K + E K K + L ++ + K +EKT +E + +
Sbjct: 5891 ILEEMRENISKLKEYIDNEKEKSKLREDELKKLQTEVQKQQSKIDMEKTNIESERAAMIR 5950
Query: 1361 MDAIHEEELRKEKVD-----KSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDL 1197
EL+K+ D K LTE E + D+E L D L+RD
Sbjct: 5951 EKQNMMTELKKKSEDVEIQMKEILTEK----ELLHNDRKLLTRDVENLQQKLID-LERDS 6005
Query: 1196 DRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIER-KLEASNLTHNDE-----LHKEK 1035
R+ +++A E ++ EA TD Q + EIE+ KLE + E + KE+
Sbjct: 6006 KRLKLDREAFE---NEKEAMKQMKTDLQIQAD-EIEKIKLETQHDRQRVEEMAAQIQKER 6061
Query: 1034 DDKKSIMNDLDRVKAEKQVLESKVSDLETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQ 855
D +++ + +R + VL K D+E ++ ++ + R L VK+
Sbjct: 6062 DKINNLIEETNR---KDMVLNEKNRDIEEKIKSIQSDKDMLEKERHNLEKTRSELYKVKE 6118
Query: 854 GLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLLKDIN 675
LEK+ E T+ +I+ + + NE + + + I EE ++ D+ +L
Sbjct: 6119 DLEKQ---KENTLAEIQKEREDVEKMNENITREMHE-IKHQEEQMNQKQDELDQL----- 6169
Query: 674 IWLSEVTELQEDLNKES----KEKQDLEKRVLELTSKLEKCICGARDGLSTIK 528
+E+ LQ++L KE K++ + R S+L+K D + T+K
Sbjct: 6170 --KTEIQNLQQELEKEKEIIMKDRSQFDLR----QSELDKQQTNMNDIMETMK 6216
Score = 70.1 bits (170), Expect = 7e-09
Identities = 113/520 (21%), Positives = 220/520 (42%), Gaps = 45/520 (8%)
Frame = -3
Query: 2018 LNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKA---L 1848
L EK+ + + D L ++ L+ A + K + E +KD+ AI++K +
Sbjct: 12750 LQEKNVQMGTILDE--LNKRQEELDAIKAKTQREKEQMGHTEELEKDELIAILQKREEIV 12807
Query: 1847 DKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILI-LHEELQKEK 1671
+ + +++ + +E D + +++ N E + L + L+K+K
Sbjct: 12808 KRHMEEIQNQREELQKEKDQFGNMQAELQKGQLEMEMHQLMLNSERDELNGMRVNLEKQK 12867
Query: 1670 DDKTALIKDLVAAEPG---------KRTVNEIVSHLESKSRSLK----EHFLREEEDEVL 1530
++ + ++L + P K+ V E+ + L + + E R E+ + +
Sbjct: 12868 EEFELMQQNLESRRPESLLEDILKEKKRVEEMAAQLSKEQEEFRNIMSETIKRMEKIKQI 12927
Query: 1529 ERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAI 1350
E I A EE +KE D + + E CE ++ + + L + + +D
Sbjct: 12928 EGEIKTKQIEMACLEELKQKELDEQKNMRE----CENQELQMRREELAKMKTEID----- 12978
Query: 1349 HEEELRKEKVDKSALTENGEGCEAE-------KQGPEKTVLDLEPTIPSLNDALQRDLDR 1191
+ ++++ K E CE E K+ PEK +++ +D + +D
Sbjct: 12979 ----IERDEIQKLRKQYEKEKCELEQIKPDLQKREPEKIDAEVQ------HDEIHGGIDS 13028
Query: 1190 VMAEKQALEKRCSDLEAKNASLT----------DNQEGHEAEIERKLEASNLTHNDELHK 1041
+ E++ +EK +DL+ K D E EAEIE+ A ND
Sbjct: 13029 LKEEREEIEKMKADLQNKLREAENMRDIMKREKDELEKKEAEIEQM--AVETEDNDSDKN 13086
Query: 1040 EKDDKKSIMNDLDRVKAEKQVLES-------KVSDLETTYSTLNNE---LQQKMDDNEAF 891
+D+ I L K +K LE + ++LET L E L +K+ + E F
Sbjct: 13087 LQDEMMKIEAILKVTKKQKNYLEQMNENLTREKTELETNCQMLEREKTELNKKVKETEEF 13146
Query: 890 -LNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISI 714
+++ + EA ++ +E RV+D A H+ ++K +++ N E+ +KK+ LEE+++
Sbjct: 13147 HMSKMEEREAERKTIE-RVMDEMAEEHE-KIKKEREELVNMEEE--IKKQRRVLEESMNE 13202
Query: 713 LTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRV 594
+T K +ELQ + ++ K+KQ LE +
Sbjct: 13203 MTKKK--------------SELQHERSELYKQKQQLEDMI 13228
Score = 69.3 bits (168), Expect = 1e-08
Identities = 108/561 (19%), Positives = 243/561 (43%), Gaps = 50/561 (8%)
Frame = -3
Query: 2051 EAAIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDE---LERKK 1881
E+ L++E +D+ K + +N+L +K + +LE T + E +E+++
Sbjct: 13771 ESMKTLLDEERRQLQDNIKTFEDQKNVLHPSKTDAVQQTDELEKFTTDIKTEKEHVEKER 13830
Query: 1880 DD----NNAIIK-----KALDKRISDLKAD-APQRDQEDDMNALIXXXXXXXXXXXXXXK 1731
++ N IIK ++L+ I K + A +R Q + + L +
Sbjct: 13831 EEIDVLNKEIIKSKEELQSLNLEIEMFKQEIAGKRAQIESLEQLRADLLAGADDIKTLVQ 13890
Query: 1730 IVSNLEVNI------LILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSL 1569
+ + + L LQK+K++ L ++ + AE K V L+ + + +
Sbjct: 13891 TEKQMAIEDTEKKTEVELQMNLQKQKNELEEL-RNTIEAE--KHQVENRKIMLDKQQKEV 13947
Query: 1568 KEHF-LREEEDEVLERSASNLAIMKAIREEELRKEKDGKSALVENG----EGC----EAE 1416
++ + + E +VLE+ S L + + E++++E++ L+E E C E+E
Sbjct: 13948 EDIMTVIKSERDVLEKEKSELNKLSHVLNEKVQREQEELERLLEKERDDIENCKKIIESE 14007
Query: 1415 KQGLEKTVLERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEP 1236
KQ +E+ E + + ++ HE L ++ DK+ + + E E EK + + +L+
Sbjct: 14008 KQSIERERAELKRLK-EEVEVQHERTLLQQ--DKNMIQKEKEHLEGEKARTTEEIHNLKE 14064
Query: 1235 TIPSLNDALQRDLDRVMAEKQALE--------------KRCSDL---EAKNASLTDNQEG 1107
I + L + A++Q E K+ D+ E TD +
Sbjct: 14065 EIKRKSSELDMLNKEIEAKRQEEELHGLPEEIEIEDHLKKEDDVLREEIIKKQQTDASQK 14124
Query: 1106 HEAEIERKLEASNLTHNDELHKEKDDKKSIMNDLDRVKAEKQVL----ESKVSDLETTYS 939
+ + + +A T DE+ K + ++ + + A++ ++ ++ S+++
Sbjct: 14125 FQLKTTSR-DAETQTSLDEITKTDERRQRALEETVATTAKQPIVIKLEDTLTSEVQEMRD 14183
Query: 938 TLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQ 759
LNNE+++ E+D L+ K ++ ++ + E + + + +++ +
Sbjct: 14184 HLNNEIKELARMKTIMKMEKDQLKQAKSDIQTQMEEFERNMEEAMEEKSRNE-------E 14236
Query: 758 TLKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLELTS 579
L + + E+ + L K K++ + +L ++ +L+ + K+K+++E +L+L
Sbjct: 14237 KLLQLTHDKEDLSNTLDKKNKEIENNTETFLKKIAQLETTIVLMKKDKENIENELLQLKQ 14296
Query: 578 -KLEKCICGARDGLSTIKEAW 519
+ E+ I D ST KE +
Sbjct: 14297 IEQEREIQRKADVTSTEKEMY 14317
Score = 68.9 bits (167), Expect = 2e-08
Identities = 118/565 (20%), Positives = 246/565 (43%), Gaps = 87/565 (15%)
Frame = -3
Query: 2000 KKC-IVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKALD-----KR 1839
+KC I N + I++ +E + +++ K L+ E ++ D+ + +I+ + +R
Sbjct: 10654 EKCDIENSKEIVQKLMVEVEEQKHEIQFQKEELDIERQKIADEQDLLIQNKSELQNENER 10713
Query: 1838 ISDL-KADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDK 1662
I +L + +R+ +M A + + ++ L E+L+K D
Sbjct: 10714 IRNLNEIIKKERETLKEMEAHLEKKKEE----------IKSVSEETRRLKEDLEKMSTDV 10763
Query: 1661 TALIKDLVAAEPGKRTVNEIVSHL----------------ESKSRSLKEHFLREEEDEVL 1530
KDL+ E ++H + K + L + +E+ + L
Sbjct: 10764 NKQNKDLMNQRDLLEQEREEINHKWKQLQQRIDEFDAQVSKQKEQDLPKEKGMKEDRKSL 10823
Query: 1529 ERSASNLAIMKAIRE-EELRKEKDGKSALVENGEG-----CEAEKQGLE--KTVLERRAS 1374
E + +N+ MK E EE++KEK+ ++ E E E E++ L K+ LER S
Sbjct: 10824 EETKANVIEMKTKAEPEEIKKEKEKENEEEEEEEEEIRVIVETERKELYQIKSELERVRS 10883
Query: 1373 NLDT--------MDAIHEEELRKEKV-------------DKSALTENGEGCEAEKQGPEK 1257
+D M I +E+ EK+ ++S L + EK EK
Sbjct: 10884 EIDHEQKKLNDYMKMIEQEKEDLEKMKSEIMKQRQQMEEERSELDNKIQQTNLEKHDIEK 10943
Query: 1256 TVLDLEPTIPSLNDA---LQRDLDRVMAEKQALEKRCSDLEAKNASL-TDNQEGHEAEIE 1089
+ +E + + + +Q + + E+Q + + L A L +N+ + + E
Sbjct: 10944 SKEIVEKLMVEVEEQRKDIQLQKEELDIERQKIADEQNLLVQNKAKLQNENERIKKVDEE 11003
Query: 1088 RKLEASNLTHND-ELHKEKDDKKSIMNDLDRVKAEKQVLESKVSD-----------LETT 945
K E L + L KEK++ +SI+ + R K + + + + +++ LE
Sbjct: 11004 IKKERETLREMEIHLKKEKEELRSIIEETQRRKEDLEKMSTDINEQKLHLKNQRDLLEQE 11063
Query: 944 YSTLNNE---LQQKMDDNEAFLNE------RDGLEAVKQGLEK---RVLDLE--ATIHDI 807
+N+E LQQ++D+ +A +++ + +E ++ LE+ R+++++ A + +I
Sbjct: 11064 REEINHEMTQLQQRIDEFDAQVSKQREDLTKQEMEEERKSLEETKARIIEMKTKAELQEI 11123
Query: 806 EMKTGKDDDYN-----EAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQE 642
+ ++D+ E E++ L + SEL+ S + + KKL D I E +L++
Sbjct: 11124 MQEKEEEDEEEMRVIVEMEREELNQIKSELKRVRSEIDHEQKKLNDDKKIIEQEKEDLEK 11183
Query: 641 DLNKESKEKQDLEKRVLELTSKLEK 567
++ ++Q +E+ EL +K+++
Sbjct: 11184 MKSEIMTQRQQMEEERSELDNKIKQ 11208
Score = 68.2 bits (165), Expect = 3e-08
Identities = 116/566 (20%), Positives = 230/566 (40%), Gaps = 63/566 (11%)
Frame = -3
Query: 2075 LESKVSVFEAAIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDE 1896
+E ++ + +A L + E D++K N+ E Q L+ + +L KT + +
Sbjct: 12927 IEGEIKTKQIEMACLEELKQKELDEQK------NMRECENQELQMRREELAKMKTEI--D 12978
Query: 1895 LERKKDDNNAIIKKALDKRISDLKADAP--QRDQEDDMNALIXXXXXXXXXXXXXXKIVS 1722
+ER D ++K +K +L+ P Q+ + + ++A +
Sbjct: 12979 IER---DEIQKLRKQYEKEKCELEQIKPDLQKREPEKIDAEVQH---------------D 13020
Query: 1721 NLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEE 1542
+ I L EE ++ + K L L AE + + LE K +++ + E+
Sbjct: 13021 EIHGGIDSLKEEREEIEKMKADLQNKLREAENMRDIMKREKDELEKKEAEIEQMAVETED 13080
Query: 1541 DEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKT--VLERRASNL 1368
++ + + ++AI L+ K K+ L + E EK LE +LER + L
Sbjct: 13081 NDSDKNLQDEMMKIEAI----LKVTKKQKNYLEQMNENLTREKTELETNCQMLEREKTEL 13136
Query: 1367 DT---------MDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLND 1215
+ M + E E ++ +++ + E E E K+ E+ V ++E I
Sbjct: 13137 NKKVKETEEFHMSKMEEREAERKTIER-VMDEMAEEHEKIKKEREELV-NMEEEIKKQRR 13194
Query: 1214 ALQRDLDRVMAEKQALEKRCSDLEAKNASLTD---------------NQEGHEAEIERKL 1080
L+ ++ + +K L+ S+L + L D Q+ + +I ++
Sbjct: 13195 VLEESMNEMTKKKSELQHERSELYKQKQQLEDMIASESKRDVDTERSRQDKEDEQILKRE 13254
Query: 1079 EASNLTHNDELHKEKDDKKSIMNDLDRVKAEKQVLESKVSD--------------LETTY 942
D+L KEK+D ++ ++R K + ++S+++D ++T
Sbjct: 13255 REEIADMKDQLLKEKEDVETTKERINREKEHIEKMQSQLNDQKEEMDLENQKLLYMKTEI 13314
Query: 941 STLNNELQQKMDDNEAFLNERDGLEAV-----KQGLEKRVL-------------DLEATI 816
N L++ M D + ER+ + A+ K+ ++ +L +++
Sbjct: 13315 QVKTNALEKMMQDLQ---KERENVNALVIQHQKEREQRDILIEENKRKEKHAEAEIQRQF 13371
Query: 815 HDIE-MKTGKDDDYNEAEKQT--LKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQ 645
DIE +K + N+ +K LK R ELE I KK K+ ++ E+Q
Sbjct: 13372 EDIESVKVRLVTESNQIDKMNSELKTRSEELENLI-------KKQQKEFE---TKENEMQ 13421
Query: 644 EDLNKESKEKQDLEKRVLELTSKLEK 567
+ K +LE++ EL +K+EK
Sbjct: 13422 RERKALEKMNAELERKSTELKNKIEK 13447
Score = 67.8 bits (164), Expect = 4e-08
Identities = 122/593 (20%), Positives = 248/593 (41%), Gaps = 81/593 (13%)
Frame = -3
Query: 2027 DELLNEKD-DKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIK-- 1857
D + + D ++ I N + I++ +E + D+ K L+ E ++ D+ +++
Sbjct: 11203 DNKIKQTDLERHDIENSKEIVQKLMVKVEEQRKDIRLQKEELDIERQKIADEQGLVVQNK 11262
Query: 1856 ----------KALDKRISDLKA-----DAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVS 1722
K +D+ I K +A R ++++M ++I
Sbjct: 11263 AKLQNENERIKEMDEEIKKEKETLKEMEAHLRKEKEEMRSVIEETQRRKKEDLEKMSTDV 11322
Query: 1721 NLEVNILILHEELQKEKDDK-----TALIKDLVAAEPGKRTVNEIVSHL-ESKSRSLKEH 1560
N + L+ +L K++ ++ T L ++ ++E + + + K L +
Sbjct: 11323 NKQNQDLMNQRDLLKQEREEINHKWTQL----------QQRIDEFDAQVSKQKEEDLTKQ 11372
Query: 1559 FLREEEDEVLERSASNLAIMKAIRE-EELRKEKDGKSALVENGEGCEAEKQGLE--KTVL 1389
EEE + LE + + MK E E+++KEK+ + V + E +K+ L+ K+ L
Sbjct: 11373 KKMEEERKSLEETKIKIIEMKTKTEPEKIKKEKEKEEEEVMRAK-VEMKKEELDQIKSQL 11431
Query: 1388 ERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDAL 1209
ER S +D HE+ +K DK + + E E K K +E L++ +
Sbjct: 11432 ERVRSEID-----HEQ--KKLNDDKKMIEQEKEDLEKMKSEIMKQRQQMEEERSELDNKI 11484
Query: 1208 -QRDLDR--VMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIER---------------K 1083
Q DL+R + K+ ++K ++E + + +E E +IER K
Sbjct: 11485 KQTDLERHDIENSKEIVQKLMVEVEEQRKDIRLQKE--ELDIERQKIADEQGLVVQNKAK 11542
Query: 1082 LEASN---LTHNDELHKEKDDKKSIMNDLDRVKAE-KQVLES----KVSDLETTYSTLNN 927
L+ N ++E+ KEK+ K + L + K E + V+E + DLE + +N
Sbjct: 11543 LQNENERIKEMDEEIKKEKETLKEMEAHLRKEKEEMRSVIEETQRRQKEDLEKMSTDVNK 11602
Query: 926 ELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATI-----HDIEMKTGKDDDYNEAEK 762
+ Q M+ + ER+ + L++R+ + +A + D+ + +++ E+
Sbjct: 11603 QNQDLMNQRDLLKQEREEINHKWTQLQQRIDEFDAQVSKQKEEDLTKQKKMEEERKSLEE 11662
Query: 761 QTL---------------KKRISELEEAISILTDKAKKLLKDINIWL----SEVTELQED 639
+ K++ E EE + + K+ L I L SE+ Q+
Sbjct: 11663 TKIKIIEMKTKTEPEKIKKEKEKEEEEVMRAKVEMKKEELDQIKSQLERVRSEIDHEQKK 11722
Query: 638 LNKESK----EKQDLEKRVLELTSKLEKCICGARDGLSTIKEAWMSDCMVPDN 492
LN + K EK+DLEK E+ + ++ + + I++ ++ C + ++
Sbjct: 11723 LNDDKKMIEQEKEDLEKMKSEIMKQRQQMEEERSELENKIRQTYIEKCDIENS 11775
Score = 67.4 bits (163), Expect = 5e-08
Identities = 92/447 (20%), Positives = 194/447 (43%), Gaps = 36/447 (8%)
Frame = -3
Query: 1622 KRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNLAIMKAIREEELRKEKDG-KSAL 1446
+ T E++ LE + R+ K R L + +++K KD K
Sbjct: 80 RMTEPELIQELEWRQRNTKHTQTETGSPPSSPREKRRLEDKSGL-SSDIQKRKDSLKRRR 138
Query: 1445 VENGEGCEAEKQGLEKTVLERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQG 1266
E E ++ E T ER + +D M ++++++++ + + +T EK
Sbjct: 139 FETMRAIEQIEKLWEGTKQER--TEIDNM----KQKIQRQQDEITRMT-------TEKGQ 185
Query: 1265 PEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIER 1086
E+T+ ++ I + + + R+ + V E++ +E+ SDL+A+ +SL Q+ E ER
Sbjct: 186 LERTITHMKAEIDHIRERMDRNKEEVNRERERVEQMRSDLQAEQSSL--QQKRDEIMTER 243
Query: 1085 K----LEASNLTHNDELHKEKDDKKSIMNDLDRVKAEKQV----LESKVSDLETTYSTL- 933
+ + L +EL ++ K M ++++K+ QV +E K+ + + +
Sbjct: 244 QNLEMIRYETLRQQEELESNRESTKHEMERMEQMKSAIQVQINEIEMKIGETQKAKDLME 303
Query: 932 ---------NNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDD 780
NEL++K +D +RD E +K L++ +++E H+ E + +
Sbjct: 304 QMKAEIEDEKNELEKKKED---IKRQRDQFEQIKLDLQQVKMEMEQRWHETEKEGLEQRA 360
Query: 779 YNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEV--TELQEDLNKESK----- 621
+ EK+ LK E++ + ++ ++ K + +S++ L+E+ E+K
Sbjct: 361 VIQREKEQLKYLQDEIQR-VREEVERNREFSKQEHARISQLRAQALEENNLIENKWHDIL 419
Query: 620 -EKQDLEKRVLELTSKLEKCICGARDGLSTIKEAW----MSDCMVPDNWVPFEDLVQGFS 456
+++DLE+ E+ E+ + +K+ W + + + + E V
Sbjct: 420 RKEKDLEEMKHEIERGREELVMNG----ELVKKEWEKIEQAKVDIQSHMISMEGRVDEIK 475
Query: 455 RKTSPLDITKT-----CDAVDISEDST 390
R+T L KT DA++ +D T
Sbjct: 476 RETERLKHIKTEMQRDKDALEKQKDDT 502
Score = 65.1 bits (157), Expect = 2e-07
Identities = 117/597 (19%), Positives = 242/597 (40%), Gaps = 108/597 (18%)
Frame = -3
Query: 2033 LNDELLNEKDDKKCIVN--------DRNILEAAKQALEYKVADLEAAKTTLNDELERKKD 1878
LN+ LN+ K ++ ++ +E K ++ + DL+ +T LN + + +D
Sbjct: 1889 LNELTLNQIKTKSDVLEKISELNSQQKDEIENEKSKIKIREYDLQQMQTDLNRQQKEMQD 1948
Query: 1877 DNNAII--KKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLE-VN 1707
NA+ K L K ++ A Q Q DM NL+
Sbjct: 1949 IQNAVFMEKSELKKSQDEI---AEQLKQVGDMMQFTQNEK-------------DNLDRER 1992
Query: 1706 ILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEV-L 1530
I+ ++LQ E+D L ++L + + K+ V LE SL E+ ++ L
Sbjct: 1993 AAIIEQKLQMERDMTHLLNRELESLKLVKKEVLNEKRLLEDCRISLMRDMQDLEQMKINL 2052
Query: 1529 ERSASNLAIMKAIREEELRKEKDGKSALVENGEGCE----AEKQGLEKTVLERRASNLDT 1362
ER + + + EE K + L E+ E AEKQ LE +E + +
Sbjct: 2053 EREKEEMQLQRQSIAEEKDKLESVLQTLAEDTEKLRIDTLAEKQKLEDAAVELQKERDEI 2112
Query: 1361 MDAIHEEELRKEKVDK----------------------SALTENGEGC------------ 1284
M+ E + ++E VDK +A+ EN
Sbjct: 2113 MNIAEETKRKREDVDKIRVGIEKQEITFKDLKADLQKEAAIVENQRQAVQKDIQNVKDME 2172
Query: 1283 ---EAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQ 1113
+ E+Q ++ V ++E +L D +Q ++D+ E+Q +E + +LE + + L +++
Sbjct: 2173 VQIQKERQYMDRLVEEIEKRTKAL-DEMQMEVDK---ERQEVESKRDELEQETSKLREDE 2228
Query: 1112 EGH----------EAEIERK-----LEASNLT----------------HNDELHKEK--D 1032
+ +AEI+++ L++ N++ N+ +K+K D
Sbjct: 2229 DEFSRQKEKNNIIQAEIQKESDNLELQSENISKERTIFELEKEHLGLRENEAEYKQKQID 2288
Query: 1031 DKKSIMN----DLDRVKAEKQVLESKVSDLETTYSTLNNELQQKMDDNEAFLNERDGLEA 864
+ ++ + +++++A+K K ++T L+++ + E+ E + +E
Sbjct: 2289 ELQNKLRMEKVQVEQMQADKDQQRKKAEYVKTARGRETTALEEQRQEMESLREEYENVEK 2348
Query: 863 VKQGLEKRVLDLEATIHDIEMKTGKDDDYNEA----------EKQTLKKRISELEEAISI 714
K+ + ++ E+ + +EM+ Y E ++Q +K I ++ + I
Sbjct: 2349 QKKHVNEQKELFESRMKSLEMENEAMKKYKEKLDKEYEDLQFQRQLFEKEIQQMRTELQI 2408
Query: 713 LTDKAKKLLKDINIWLSEV------TELQEDLNKESK--EKQDLEKRVLELTSKLEK 567
+ ++ K++ I V E Q+ + ++SK E ++ K++ S++EK
Sbjct: 2409 EAENIERKKKELEIQKPAVYTETYMLETQKPVVEKSKTDELDEVRKKINADLSEVEK 2465
Score = 65.1 bits (157), Expect = 2e-07
Identities = 108/563 (19%), Positives = 242/563 (42%), Gaps = 74/563 (13%)
Frame = -3
Query: 2033 LNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIK- 1857
L++++ +K I + I+E +E + D++ K L+ E ++ D+ N +++
Sbjct: 10927 LDNKIQQTNLEKHDIEKSKEIVEKLMVEVEEQRKDIQLQKEELDIERQKIADEQNLLVQN 10986
Query: 1856 -----------KALDKRISDLKADAPQRD-----QEDDMNALIXXXXXXXXXXXXXXKIV 1725
K +D+ I + + + +++++ ++I +
Sbjct: 10987 KAKLQNENERIKKVDEEIKKERETLREMEIHLKKEKEELRSIIEETQRRKEDLEKMSTDI 11046
Query: 1724 SNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREE 1545
+ ++++ + L++E+++ + L ++ ++E + + + L + + EE
Sbjct: 11047 NEQKLHLKNQRDLLEQEREEINHEMTQL------QQRIDEFDAQVSKQREDLTKQEM-EE 11099
Query: 1544 EDEVLERSASNLAIMKAIRE-EELRKEKDGKS-----ALVENGEGCEAEKQGLEKTVLER 1383
E + LE + + + MK E +E+ +EK+ + +VE E E+ K+ L+R
Sbjct: 11100 ERKSLEETKARIIEMKTKAELQEIMQEKEEEDEEEMRVIVE----MEREELNQIKSELKR 11155
Query: 1382 RASNLDTMDAIHEEE--------LRKEKVD----KSALTENGEGCEAEKQGPEKTV--LD 1245
S +D HE++ + +EK D KS + + E E+ + + D
Sbjct: 11156 VRSEID-----HEQKKLNDDKKIIEQEKEDLEKMKSEIMTQRQQMEEERSELDNKIKQTD 11210
Query: 1244 LEP-TIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASN 1068
LE I + + +Q+ + +V +++ + + +L+ + + D Q G + + KL+ N
Sbjct: 11211 LERHDIENSKEIVQKLMVKVEEQRKDIRLQKEELDIERQKIADEQ-GLVVQNKAKLQNEN 11269
Query: 1067 ---LTHNDELHKEKDDKKSIMNDLDRVKAE-KQVLES----KVSDLETTYSTLNNELQQK 912
++E+ KEK+ K + L + K E + V+E K DLE + +N + Q
Sbjct: 11270 ERIKEMDEEIKKEKETLKEMEAHLRKEKEEMRSVIEETQRRKKEDLEKMSTDVNKQNQDL 11329
Query: 911 MDDNEAFLNERDGLEAVKQGLEKRVLDLEATI-----HDIEMKTGKDDDYNEAEKQTL-- 753
M+ + ER+ + L++R+ + +A + D+ + +++ E+ +
Sbjct: 11330 MNQRDLLKQEREEINHKWTQLQQRIDEFDAQVSKQKEEDLTKQKKMEEERKSLEETKIKI 11389
Query: 752 -------------KKRISELEEAISILTDKAKKLLKDINIWL----SEVTELQEDLNKES 624
K++ E EE + + K+ L I L SE+ Q+ LN +
Sbjct: 11390 IEMKTKTEPEKIKKEKEKEEEEVMRAKVEMKKEELDQIKSQLERVRSEIDHEQKKLNDDK 11449
Query: 623 K----EKQDLEKRVLELTSKLEK 567
K EK+DLEK E+ + ++
Sbjct: 11450 KMIEQEKEDLEKMKSEIMKQRQQ 11472
Score = 62.8 bits (151), Expect = 1e-06
Identities = 107/536 (19%), Positives = 227/536 (42%), Gaps = 55/536 (10%)
Frame = -3
Query: 2027 DELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKAL 1848
+ L KD+ + +R+ LE K ++E NDE++++K + K L
Sbjct: 7957 ETLRGMKDEVQAARKERSELENMKLEFLTMKKNMEKTYEQQNDEIQKEKQQIESS-KMLL 8015
Query: 1847 DKRISDLKADAPQRDQED-----DMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEEL 1683
+ +DL+ + +++ D L+ KI+ NLE L EE
Sbjct: 8016 SRERNDLEQNRADLERQKQIMALDKQKLLAENELLEREKADVIKIIENLES----LREEA 8071
Query: 1682 QKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVLE--RSASNL 1509
+E+ +TA + +R E++ +E+ S E F +++++E R L
Sbjct: 8072 TRERATETA--------QATRRDSEELMQKMEALSM---EDFQEASKNQMVELKRQIDKL 8120
Query: 1508 AIMKAI---REEELRKEKDG-----------KSALVENGEGCEAEKQGLEKTVLERRASN 1371
+KA ++ EL+K K +S ++++ + +++ + LE ++R+ +
Sbjct: 8121 IELKADLLQQQTELKKTKADLKQQMDDLEKTRSEILKHEKDTDSKTRELELIEIQRQKDD 8180
Query: 1370 LDT------MDAIHEEELRKEKV-DKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLN-- 1218
L+T ++ E LR E V +K L + + ++ EK D+ +N
Sbjct: 8181 LETRIQKLTLEKRDLEVLRSEIVLEKKDLDQKMKQVIRKRDEMEKIRSDIANATEEINRE 8240
Query: 1217 ----DALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQE-------------GHEAEIE 1089
+ L+ ++ + + L +R ++LE + ++ TD + + E+E
Sbjct: 8241 RQELEILRNNVQSARHDFELLLERTANLEDEESAATDIERLVLEVVKIREMVRNLKGEME 8300
Query: 1088 RKLEASNLTHNDELHKEKDDKKSIMNDLDRVKAEKQVLESKVS-------DLETTYSTLN 930
R++E S + DE K + + + D+ +++ L ++ +LE + L
Sbjct: 8301 RRMEKSKV-EIDEKEIFKSEIQRFIQDIGQIRENLGGLGEEIEKTRRDKRELEKMRAELA 8359
Query: 929 NELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLK 750
+ Q++ E ER+ LE +K + + D+E +E K++ + Q K
Sbjct: 8360 EKQQEQESMREMLHKEREELEQLKDEINREKEDVEIRRELVEAVIDKEEMKEFTDIQKYK 8419
Query: 749 KRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLN-KESKEKQDLEKRVLEL 585
+ + + E +LT K+ L +N + ++ + E++N + K++ +LE EL
Sbjct: 8420 EELQSVTE--ELLT--KKRDLDQLNSDVQDLRQTIEEINIQHGKKRAELEGIGFEL 8471
Score = 62.4 bits (150), Expect = 2e-06
Identities = 121/544 (22%), Positives = 221/544 (40%), Gaps = 48/544 (8%)
Frame = -3
Query: 2081 QALESKVSVFEAAIATLNDELLNEKDDKKCIVNDRNILEAAKQ--ALEYKVADLEAAK-- 1914
Q L+++ + E + T ND LL E +K+ ND + E K+ ALE + D+ K
Sbjct: 13649 QLLQTEKEILEKS-KTEND-LLREDLEKQRKRNDLTLQELRKEKMALEQMITDITKEKDA 13706
Query: 1913 -TTLNDELERKKDD--NNAIIKKALDKRISDLKADAPQRD-----QEDDMNALIXXXXXX 1758
+L +E+ K+ + N K + DL+ R Q+ +++ I
Sbjct: 13707 VASLQNEVSLKQHELKNKETELDEQRKEMDDLRMQLEMRQNSTNKQQQEVDVFIVENMKM 13766
Query: 1757 XXXXXXXXKIVSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKS 1578
++LE +L EE ++ +D+ P K + LE +
Sbjct: 13767 R----------NDLESMKTLLDEERRQLQDNIKTFEDQKNVLHPSKTDAVQQTDELEKFT 13816
Query: 1577 RSLK---EHFLREEEDEVLERSASNLAIMKAIRE--------EELRKEKDGKSALVENGE 1431
+K EH +E E E N I+K+ E E ++E GK A +E+ E
Sbjct: 13817 TDIKTEKEHVEKERE----EIDVLNKEIIKSKEELQSLNLEIEMFKQEIAGKRAQIESLE 13872
Query: 1430 GCEAE----KQGLEKTVLERRASNLDTMDAIHEEELRKE-KVDKSALTENGEGCEAEKQG 1266
A+ ++ V + ++ + E EL+ + K+ L E EAEK
Sbjct: 13873 QLRADLLAGADDIKTLVQTEKQMAIEDTEKKTEVELQMNLQKQKNELEELRNTIEAEKHQ 13932
Query: 1265 PEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIER 1086
E + L+ + D + + +E+ LEK S+L + L + + + E+ER
Sbjct: 13933 VENRKIMLDKQQKEVEDIMTV----IKSERDVLEKEKSELNKLSHVLNEKVQREQEELER 13988
Query: 1085 KLEASNLTHNDELHKEKDDKKSIMNDLDRVKAEKQVLESKVSDLETTYSTLNNELQQKM- 909
LE KE+DD I N +++EKQ +E + ++L+ + + ++ +
Sbjct: 13989 LLE-----------KERDD---IENCKKIIESEKQSIERERAELKRLKEEVEVQHERTLL 14034
Query: 908 -DDNEAFLNERDGLEA-----------VKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAE 765
D E++ LE +K+ ++++ +L+ +IE K +++ + E
Sbjct: 14035 QQDKNMIQKEKEHLEGEKARTTEEIHNLKEEIKRKSSELDMLNKEIEAKRQEEELHGLPE 14094
Query: 764 ----KQTLKKRISELEEAI--SILTDKAKKL-LKDINIWLSEVTELQEDLNKESKEKQDL 606
+ LKK L E I TD ++K LK + T L E + + ++ L
Sbjct: 14095 EIEIEDHLKKEDDVLREEIIKKQQTDASQKFQLKTTSRDAETQTSLDEITKTDERRQRAL 14154
Query: 605 EKRV 594
E+ V
Sbjct: 14155 EETV 14158
Score = 62.0 bits (149), Expect = 2e-06
Identities = 117/582 (20%), Positives = 218/582 (37%), Gaps = 78/582 (13%)
Frame = -3
Query: 2081 QALESKVS-VFEAAIATLND--ELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKT 1911
Q LE+KV V + T D EL +E ++K I+ + N + Q L+ + E K+
Sbjct: 14700 QTLETKVQDVLQLTDYTTQDQEELHDEMENKMKIILELNEAKKDLQKLKEECRSAEEEKS 14759
Query: 1910 TLNDELERKKDDNNAIIKKALD-----KRISDLKADAPQ--------------------- 1809
+ + LER+++ + + L ++ +K + Q
Sbjct: 14760 VIMESLERRRNSLEKVQSEVLSLTQEIDHLAQIKTEMQQIEIKMQIQTRSVATQWETDVQ 14819
Query: 1808 ----RDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDKTALIKDL 1641
++ + + V+ LE L E+Q+ +D ++D+
Sbjct: 14820 IQQGQEATETTGHITKKSEEEISAKKTKQPTVTKLEDT---LTSEVQEMRDSLNKEMEDV 14876
Query: 1640 VAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNLAIMKAIRE-EELRKEK 1464
+ + + + +S ++ E F R E+ + E+S + +++ + E+L
Sbjct: 14877 ARMKTIMKMEKDQLEQAKSDIQTQMEEFERNMEEAMEEKSRNEEKLLQLTHDKEDLSNTL 14936
Query: 1463 DGKSALVENG----------------------EGCEAEKQGLEKTVLERRASNLDTMDAI 1350
D K+ +EN E E E L++T ER T D
Sbjct: 14937 DKKNKEIENNTETSLKKIAQLETTIVLMKKDKENIENELLQLKQTEQEREIQR-GTDDTS 14995
Query: 1349 HEEELRKEKVD-KSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQ 1173
+E E EKV K+ L +N E +K+ + L L D+ + D +R E Q
Sbjct: 14996 NEREKYDEKVTYKTELEDNKE----KKKPDRDSSLKLTDA-----DSAKTDGER---EAQ 15043
Query: 1172 ALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASNLTHNDELHKEKDDKKSIMNDLDRVK 993
LE + D+ T +QE ELH E ++K I+ +L+ K
Sbjct: 15044 TLETKVQDVLQLTDDTTQDQE-------------------ELHDEMENKMKIILELNEAK 15084
Query: 992 AEKQVLESKVSDLETTYSTLNNELQQKMDDNE-------AFLNERDGLEAVKQGLEKRVL 834
+ Q L+ K E S + L+++ + E E + L +K +++
Sbjct: 15085 KDLQKLKEKCRSAEEEKSVIMESLERRRNSLEKVQSEVLTLTQEIEHLAQIKTEMQQIET 15144
Query: 833 DLEATIHDIEMKTGKDDDYNEAEKQTLKKR---ISELEEAISILTDKAKKLLKDINIWLS 663
++ + + D + ++ + R + EE IS K + K + S
Sbjct: 15145 KMQRQTRSVATQWETDVQIQQEGQEATETRGHITKKSEEEISAKKTKQPTVTKLEDTLTS 15204
Query: 662 EVTELQEDLNKESK-----------EKQDLEKRVLELTSKLE 570
EV E+++ LNKE + EK LE+ +L ++E
Sbjct: 15205 EVQEMRDSLNKEMEDVERMKTMMKMEKDQLEQAKSDLQRQME 15246
Score = 60.5 bits (145), Expect = 6e-06
Identities = 105/514 (20%), Positives = 211/514 (41%), Gaps = 39/514 (7%)
Frame = -3
Query: 1985 NDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKALDKRISDLKADAPQR 1806
++ ++ EA Q AD+E ELE+ KD+ K + K DL+ +
Sbjct: 1701 DELSLREATLQTATQTTADMELQLELQKQELEQTKDEMER-TKLEVQKGWVDLQTQIAES 1759
Query: 1805 DQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDKTALIKDLVAAEP 1626
++++M + +++ + ++ E+ E D K L K+ E
Sbjct: 1760 REKEEMVRI---------ELEKARDVLNRIRQDVET--EKQTMEADLKFTLAKEFENLEA 1808
Query: 1625 GKRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNLAIMKAIREEELRKEKDGKSAL 1446
++ + + LE+ L + E +ERS N+ +E + ++ L
Sbjct: 1809 QRKMMEDEKRALENMKYEL------QRESGYIERSKHNM-------HDERQNMENWAEKL 1855
Query: 1445 VENGEGCEAEKQGLE--KTVLERRASNLDTMDAIHEEELRKEKVDKSAL-------TENG 1293
+ E E ++ ++ +T R +L+ + ++E L + K L ++
Sbjct: 1856 KQEWEELEKKRHDMQQLQTERSREIKDLENLRELNELTLNQIKTKSDVLEKISELNSQQK 1915
Query: 1292 EGCEAEKQGPEKTVLDLEPTIPSLN---DALQRDLDRVMAEKQALEKRCSDLEAKNASLT 1122
+ E EK + DL+ LN +Q + V EK L+K ++ + +
Sbjct: 1916 DEIENEKSKIKIREYDLQQMQTDLNRQQKEMQDIQNAVFMEKSELKKSQDEIAEQLKQVG 1975
Query: 1121 DNQEGHEAE-----------IERKLEAS-NLTH--NDELHKEKDDKKSIMNDLDRVKAEK 984
D + + E IE+KL+ ++TH N EL K KK ++N+ ++ +
Sbjct: 1976 DMMQFTQNEKDNLDRERAAIIEQKLQMERDMTHLLNRELESLKLVKKEVLNEKRLLEDCR 2035
Query: 983 QVLESKVSDLETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGL----EKRVLDLEA-- 822
L + DLE L E ++ ++ E+D LE+V Q L EK +D A
Sbjct: 2036 ISLMRDMQDLEQMKINLEREKEEMQLQRQSIAEEKDKLESVLQTLAEDTEKLRIDTLAEK 2095
Query: 821 -TIHD--IEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTE 651
+ D +E++ +D+ N AE+ KR E + I + +K + KD+ L +
Sbjct: 2096 QKLEDAAVELQKERDEIMNIAEE---TKRKREDVDKIRVGIEKQEITFKDLKADLQKEAA 2152
Query: 650 LQED----LNKESKEKQDLEKRVLELTSKLEKCI 561
+ E+ + K+ + +D+E ++ + +++ +
Sbjct: 2153 IVENQRQAVQKDIQNVKDMEVQIQKERQYMDRLV 2186
>ref|XP_685984.6| PREDICTED: nesprin-1 isoform X1 [Danio rerio]
Length = 15997
Score = 103 bits (256), Expect = 8e-19
Identities = 128/547 (23%), Positives = 231/547 (42%), Gaps = 48/547 (8%)
Frame = -3
Query: 2033 LNDELLNEKDDKKCIVND----RNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNA 1866
+ +EL EK+ + D + IL+ K A E +ADL+ K+ L + E
Sbjct: 5015 MTEELKKEKESFTHLAEDTKTEKKILDKMKVANESLMADLQKEKSNLEEMRENISKQTED 5074
Query: 1865 IIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEE 1686
K+ R+ + + + Q + + K V +L+ + L +
Sbjct: 5075 SEKEKEKIRLREDELEQLQAEIHKQQGEIKMEKSNNESERAAIIKDVKDLQHKMFSLDRD 5134
Query: 1685 LQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVL-------- 1530
L+ K D+ A E + + +I + L+ K+ +++ L + D
Sbjct: 5135 LESLKLDREAF-------ENEREVLKQIKTDLKRKAEEIEKIKLETQHDRQRVEEMTAQI 5187
Query: 1529 --ERSASNLAIMKAIREEELRKE-----KDGKSALVENGEGCEAEKQGLEKT--VLERRA 1377
ER N I + R++ + E K+ A+ + + E EK LEKT L R
Sbjct: 5188 QKERDKINNLIEETNRKDMVLNEIKTEIKEKIKAIESDRDMLEKEKHDLEKTRSKLLRAK 5247
Query: 1376 SNLDTMDAIHEEELRKEKVDKSALTE------NGEGCEAEKQGPEKTVLD-LEPTIPSLN 1218
NL+ I E++KE+ D + E + + E+ ++ LD L+ I +L
Sbjct: 5248 ENLEKQRKIKLAEIQKEREDLEKMNEKFTIEIHDIKHQEEQMKQKQDELDQLKTEIQNLQ 5307
Query: 1217 DALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIER--KLEASNLTHNDELH 1044
L+++ + +M ++ L+ R S+L+ + ++ D E + E ++ K + E+
Sbjct: 5308 QELEKEKEIIMKDRSQLDLRQSELDKQQTNVNDIMETMKNERKQLDKDKEETEEQKQEME 5367
Query: 1043 KEKDD----KKSIMNDLDRVKAEKQVLESKVSDLETTYSTLNNELQQKMDDNEAFLNERD 876
KEK D +KS+ DL +K +KQVLE + S LE L E + E NER
Sbjct: 5368 KEKHDFDQSRKSLDEDLKMMKLQKQVLEDEKSKLEQMKIELEREAVEIRKIKEEIQNERQ 5427
Query: 875 GLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTL------KKRISELEEAISI 714
LE + + L++ DL + + D+ A + TL K + E+ E IS
Sbjct: 5428 NLEKMTEALKEEREDL---AEETKKNNQVLDEMKVANESTLADILREKSNLEEMRENISK 5484
Query: 713 LTDKAKKLLKDINIWLSEVTELQEDLNKE----SKEKQDLEKRVLELTSKLE----KCIC 558
T+ + +++ + E+ +LQ +++K+ KEK ++E + +E K IC
Sbjct: 5485 QTEDVENKKENLRLREDELRQLQAEIHKQQREIEKEKINIESERAAIIKDVEDLQHKIIC 5544
Query: 557 GARDGLS 537
RD S
Sbjct: 5545 LDRDAES 5551
Score = 100 bits (248), Expect = 7e-18
Identities = 131/576 (22%), Positives = 258/576 (44%), Gaps = 33/576 (5%)
Frame = -3
Query: 2027 DELLNEKDDK-----KCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAI 1863
D +LNEK+ K I +D+++LE K LE ++L K ++LE++K++ A
Sbjct: 6492 DMVLNEKNRDIEKKIKSIQSDKDMLEKEKHDLEKTRSELYKVK----EDLEKQKENTLAQ 6547
Query: 1862 IKKA---LDKRISDLKADAPQ-RDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILIL 1695
I+K L+K ++ + + + QE+ MN + L+ I L
Sbjct: 6548 IQKEREDLEKMNENITREMHEIKHQEEQMNQ--------------KQDELDQLKTEIQNL 6593
Query: 1694 HEELQKEKD----DKTALIKDLVAAEPGKRTVNEIVSHLESKSRSL-KEHFLREEEDEVL 1530
+EL+KEK+ ++ L + + + +N+I+ ++++ + L K+ EE+ + +
Sbjct: 6594 QQELEKEKEIIMKARSQLDRRQSELDKQQTNMNDIMETMKNERKQLDKDKEEMEEQKQEM 6653
Query: 1529 ERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAI 1350
E+ N+ + +E+L+ K K + E E K LE+ + R +T +
Sbjct: 6654 EKERDNMDQSRKSLDEDLKMMKLQKQVIEEEKNKLEQMKIELEREADDIRKIKEETQNKR 6713
Query: 1349 H-----EEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVM 1185
EEL+KE+ D + L E+ + EK ++ + E ++ L Q++ +
Sbjct: 6714 QILEKMAEELKKERKDVAHLAED---TKREKNSLDEMKVANESSMADL----QKEKSNLE 6766
Query: 1184 AEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASNLTHNDELHKEKDDKKSIMNDL 1005
K+ + K+ D+E + D E E+E+ L+A E+HK++ + + +++
Sbjct: 6767 EMKENISKQTEDIEKEK----DKIRLREDELEQ-LQA-------EIHKQQSETEIEKSNI 6814
Query: 1004 DRVKAEKQVLESKVSDLETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLE 825
+R E+ + V DL++ +L+ + + D EAF NE++ L+ +K LE+ ++E
Sbjct: 6815 ER---ERAAIIKDVEDLQSKIISLDRDAESLKLDREAFENEKEELKQMKTELEREADEIE 6871
Query: 824 ----ATIHD----IEMKTGKDDDYNEAEKQTLKKRI------SELEEAISILTDKAKKLL 687
T H+ EM + N KQ K ++ E+E+ + K L
Sbjct: 6872 KIKLETQHERQRVEEMTADFMETMNNERKQLDKNKVMIEEQKQEMEKKRDDMDQSRKSLD 6931
Query: 686 KDINIWLSEVTELQEDLNKESKEKQDLEKRVLELTSKLEKCICGARDGLSTIKEAWMSDC 507
+D+ + ++ L+E+ NK + K LE+ E+ SK+++ R L + A +
Sbjct: 6932 EDLKMMKAQKQVLEEEKNKLEQMKIGLEREADEI-SKIKEETQNERQNLEKMANALKEE- 6989
Query: 506 MVPDNWVPFEDLVQGFSRKTSPLDITKTCDAVDISE 399
E L + RK LD K + +++
Sbjct: 6990 --------REYLAEEIKRKNQVLDKIKVANESTLAD 7017
Score = 97.1 bits (240), Expect = 6e-17
Identities = 130/534 (24%), Positives = 241/534 (45%), Gaps = 47/534 (8%)
Frame = -3
Query: 2027 DELLNE-----KDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLND-------ELERK 1884
D +LNE K+ K I +DR++LE K LE + L AK L E++++
Sbjct: 5205 DMVLNEIKTEIKEKIKAIESDRDMLEKEKHDLEKTRSKLLRAKENLEKQRKIKLAEIQKE 5264
Query: 1883 KDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNI 1704
++D + +K I D+K Q Q+ D + L+ I
Sbjct: 5265 REDLEKMNEK-FTIEIHDIKHQEEQMKQKQDE--------------------LDQLKTEI 5303
Query: 1703 LILHEELQKEKD----DKTALIKDLVAAEPGKR--TVNEIVSHLESKSRSL-KEHFLREE 1545
L +EL+KEK+ D++ L DL +E K+ VN+I+ ++++ + L K+ EE
Sbjct: 5304 QNLQQELEKEKEIIMKDRSQL--DLRQSELDKQQTNVNDIMETMKNERKQLDKDKEETEE 5361
Query: 1544 EDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLD 1365
+ + +E+ + + +E+L+ K K L + E K LE+ +E R
Sbjct: 5362 QKQEMEKEKHDFDQSRKSLDEDLKMMKLQKQVLEDEKSKLEQMKIELEREAVEIRKIK-- 5419
Query: 1364 TMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVM 1185
+ I E EK+ + AL E E E + + + +++ S + R+ +
Sbjct: 5420 --EEIQNERQNLEKMTE-ALKEEREDLAEETKKNNQVLDEMKVANESTLADILREKSNLE 5476
Query: 1184 AEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASNLTHNDELHKEKDDKKSIMNDL 1005
++ + K+ D+E K +N E E+ R+L+A E+HK++ + I +
Sbjct: 5477 EMRENISKQTEDVENKK----ENLRLREDEL-RQLQA-------EIHKQQ---REIEKEK 5521
Query: 1004 DRVKAEKQVLESKVSDLETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLE 825
+++E+ + V DL+ L+ + + D EAF NE++ L+ +K LE+ ++E
Sbjct: 5522 INIESERAAIIKDVEDLQHKIICLDRDAESLKLDREAFENEKEVLKQMKTELEREADEIE 5581
Query: 824 ----ATIHD--------IEMKTGKDDDYNEAEK-----QTLKKRISELEEAI-SILTDK- 702
T HD +++ +D+ N E+ L ++ ++EE I SI +DK
Sbjct: 5582 KIKLETQHDRQRVEEMAAQIQKDRDEINNLIEETNRKDMVLNEKNRDIEEKIKSIQSDKD 5641
Query: 701 -AKKLLKDINIWLSEVTELQEDLNKE--------SKEKQDLEKRVLELTSKLEK 567
+K D+ SE+ +++EDL K+ KE++DLEK +T ++ +
Sbjct: 5642 MLEKEKHDLEKTRSELYKVKEDLEKQKENTLAEIQKEREDLEKMNENITREMHE 5695
Score = 93.2 bits (230), Expect = 8e-16
Identities = 131/541 (24%), Positives = 244/541 (45%), Gaps = 54/541 (9%)
Frame = -3
Query: 2027 DELLNEKDDK-----KCIVNDRNILEAAKQALE------YKVA-DLEAAKTTLNDELERK 1884
D +LNEK+ K I +D+++LE + LE YKV DLE K E++++
Sbjct: 6075 DMVLNEKNRDIEEKIKSIQSDKDMLEKERHNLEKTRSELYKVKEDLEKQKENTLAEIQKE 6134
Query: 1883 KDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNI 1704
++D + + + + + ++K Q +Q+ D + L+ I
Sbjct: 6135 REDVEKM-NENITREMHEIKHQEEQMNQKQDE--------------------LDQLKTEI 6173
Query: 1703 LILHEELQKEKD----DKTALIKDLVAAEPGKR--TVNEIVSHLESKSRSL-KEHFLREE 1545
L +EL+KEK+ D++ DL +E K+ +N+I+ ++++ + L K+ EE
Sbjct: 6174 QNLQQELEKEKEIIMKDRSQF--DLRQSELDKQQTNMNDIMETMKNERKQLDKDKEEMEE 6231
Query: 1544 EDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLD 1365
+ + +E+ + + +++L+ K K E E K LE+ E R +
Sbjct: 6232 QKQEMEKEKHDFDQSRKSLDKDLKMMKLQKQVFEEEKNKLEQMKIELEREADEIRKIKEE 6291
Query: 1364 TMDAIHE-----EELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRD 1200
T + EEL+KEK + L E+ + E+ +LD + N++L D
Sbjct: 6292 TQNERQSLEKMTEELKKEKESFTHLAEDTK--------KEQEILD---KVKVANESLMAD 6340
Query: 1199 LDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIER--KLEASNLTHNDELHKEKDDK 1026
L + EK LE+ ++ + + + +E + +L+A E+ KEK +
Sbjct: 6341 LQK---EKSNLEEMRENISKQTEDVENKKENLRLREDELWQLQAEIYKQQREIEKEKIN- 6396
Query: 1025 KSIMNDLDRVKAEKQVLESKVSDLETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLE 846
+++E+ + V DL+ +L+ + + D EAF NER+ L+ +K LE
Sbjct: 6397 ---------IESERAAIIKNVEDLQHKIISLDRDSESLKLDREAFENEREVLKQMKTELE 6447
Query: 845 KRVLDLE----ATIHD---IEMKTG---KD-DDYNEAEKQT------LKKRISELEEAI- 720
+ ++E T HD +E T KD D N ++T L ++ ++E+ I
Sbjct: 6448 READEIEKIKLETQHDRQRVEEMTAQIQKDRDKINNLIEETNRKDMVLNEKNRDIEKKIK 6507
Query: 719 SILTDK--AKKLLKDINIWLSEVTELQEDLNKE--------SKEKQDLEKRVLELTSKLE 570
SI +DK +K D+ SE+ +++EDL K+ KE++DLEK +T ++
Sbjct: 6508 SIQSDKDMLEKEKHDLEKTRSELYKVKEDLEKQKENTLAQIQKEREDLEKMNENITREMH 6567
Query: 569 K 567
+
Sbjct: 6568 E 6568
Score = 91.7 bits (226), Expect = 2e-15
Identities = 116/521 (22%), Positives = 217/521 (41%), Gaps = 35/521 (6%)
Frame = -3
Query: 2045 AIATLNDELLNEKDDKKCIVND----RNILEAAKQALEYKVADLEAAKTTLNDELERKKD 1878
++ + +EL EK+ + D + IL+ K A E +A+L+ K+ + E
Sbjct: 3885 SLEKMTEELKREKESFTHLAEDTKKEQEILDEIKVANESLMAELQKEKSNFEEMRENISK 3944
Query: 1877 DNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILI 1698
+ K + R+ + + Q + + KIV +L+ I+
Sbjct: 3945 QTEDVKNKKENLRLREDELGQLQAEIHKQQREIEKEKSNIESERAAIIKIVEDLQHKIIS 4004
Query: 1697 LHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEE---DEVLE 1527
L + + K D+ A + + K + +E + R EE E
Sbjct: 4005 LDRDAESLKLDREAFENEREVLKQMKTELERETDEIEKIKLETQHDRQRVEEMTAQITKE 4064
Query: 1526 RSASNLAIMKAIREEELRKEKDGK-----SALVENGEGCEAEKQGLEKTV---------L 1389
R N I + R++ + EK+ ++ + + E EK LEKT L
Sbjct: 4065 RDKINNLIEETNRKDMVLNEKNRDIEEKIKSIQSDKDMLEKEKHNLEKTRSELYKVKEDL 4124
Query: 1388 ERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKT--VLDLEPTIPSLND 1215
E++ N T+ I +E EK++++ E E E+Q +K + L+ I +L
Sbjct: 4125 EKQKEN--TLAEIQKEREDLEKMNENITIEMHEIKHQEEQMKQKQDELDQLKTEIQNLQQ 4182
Query: 1214 ALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEG--HEAEIERKLEASNLTHNDELHK 1041
L+++ + +M ++ L+ R S+L+ + ++ D E +E ++ K + E+ K
Sbjct: 4183 ELEKEKEIIMKDRSELDLRQSELDKQQTNMNDIIETMKNERKLLDKDKEEMEEQKQEMEK 4242
Query: 1040 EKDDK----KSIMNDLDRVKAEKQVLESKVSDLETTYSTLNNELQQKMDDNEAFLNERDG 873
E+D+ KS+ DL +K +KQV+E + + LE L E + E NER
Sbjct: 4243 ERDNMDQSIKSLDEDLKMMKLQKQVIEEEKNKLEQMKFELQREADEIRKIKEETQNERQS 4302
Query: 872 LEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTL------KKRISELEEAISIL 711
LE + + L K DL + + D+ A K ++ K+ + E+ E IS
Sbjct: 4303 LEKMTKALIKEREDLVHLAEYTKREKEMLDEMQVANKSSMADLQREKRILEEMRENISKQ 4362
Query: 710 TDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLE 588
T+ + + + E+ +LQ ++ K+ E D+EK +E
Sbjct: 4363 TEDIENEKEKSKLREDELKKLQTEVQKQQSE-IDMEKTNIE 4402
Score = 91.7 bits (226), Expect = 2e-15
Identities = 117/514 (22%), Positives = 225/514 (43%), Gaps = 33/514 (6%)
Frame = -3
Query: 2027 DELLNEKDDK-----KCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAI 1863
D +LNE D K I +D+++LE + LE ++L AK L + E ++ D +
Sbjct: 4535 DMVLNEMDRDIEEKIKSIQSDKDMLEKERHNLEKTRSELARAKENLETQREIERKDIEKM 4594
Query: 1862 IKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEEL 1683
KK + + + ++K Q Q+ D + L+ I L +EL
Sbjct: 4595 -KKNISREMHEIKHQEEQMKQKQDE--------------------LDQLKTEIQNLQQEL 4633
Query: 1682 QKEKDD--KTALIKDLVAAEPGKR--TVNEIVSHLESKSRSL-KEHFLREEEDEVLERSA 1518
+KEK+ K DL +E K+ +N+I+ ++++ + L K+ EE+ + +E+
Sbjct: 4634 EKEKEIIMKARSQLDLRQSELDKQQTNMNDIMETMKNERKQLDKDKEETEEQKQEMEKEK 4693
Query: 1517 SNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHEEE 1338
+ + +E+L+ K K + E E K K LER A +E
Sbjct: 4694 HDFDQSRKSLDEDLKMMKLQKQVIEE-----EKSKLKQMKIELEREA-----------DE 4737
Query: 1337 LRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKR 1158
+RK K + T+N E+Q EK L+ L++ +R + K A E
Sbjct: 4738 IRKVKEE----TQN------ERQIFEKMTEALKKEREDLSEDAKRKNQVLDEMKVANEST 4787
Query: 1157 CSDLEAKNASLTDNQEG---HEAEIERKLEASNLTHND------ELHKEKDDKKSIMNDL 1005
+D+ + ++L + +E ++E K E L E+HK++ + + +++
Sbjct: 4788 LADILRERSNLQEMRENISKQTEDVENKKEKIRLREEKLKQLQAEIHKQQSETEKEKSNI 4847
Query: 1004 DRVKAEKQVLESKVSDLETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLE 825
+R E+ + V DL++ +L+ + + D EAF NE++ L+ +K LE+ ++E
Sbjct: 4848 ER---ERAAIIKDVEDLQSKIISLDRDAESLKLDREAFENEKEELKQMKTELEREADEIE 4904
Query: 824 ----ATIHDIEMKTGKDDDYNEA----------EKQTLKKRISELEEAISILTDKAKKLL 687
T H+ + D+ E K+ ++++ E+E+ + K L
Sbjct: 4905 KIKLETQHERQRVEEMTADFMETMNNERKQLNKNKEEMQEQKQEMEKERHDMDQSRKSLD 4964
Query: 686 KDINIWLSEVTELQEDLNKESKEKQDLEKRVLEL 585
K++ + + ++E+ NK + K +LEK E+
Sbjct: 4965 KNLKMMKLQKQVIEEEKNKLEQMKIELEKEADEI 4998
Score = 91.3 bits (225), Expect = 3e-15
Identities = 133/567 (23%), Positives = 248/567 (43%), Gaps = 62/567 (10%)
Frame = -3
Query: 2081 QALESKVSVFEAAIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADL-----EAA 1917
+ LES + + + L +LL + D + + DR +LE K+ L+ DL E
Sbjct: 3639 ELLESDRKLLKKDVENLQQKLLIIESDSESLKQDRELLENEKEVLKQMKTDLQGEAEEIE 3698
Query: 1916 KTTLNDELERKK-DDNNAIIKKA----------LDKRISDLKADAPQRDQEDDMNALIXX 1770
K L + ER++ ++ A I+K + + I D+K Q Q+ D
Sbjct: 3699 KIKLETQHERQRVEEMTAQIQKDREYLQKMNDNITREIHDIKYQEKQMKQKQDE------ 3752
Query: 1769 XXXXXXXXXXXXKIVSNLEVNILILHEELQKEKD----DKTALIKDLVAAEPGKR--TVN 1608
+ L+ I L +EL+KEK+ D++ L DL +E K+ +N
Sbjct: 3753 --------------LDQLKTEIQNLQQELEKEKEIIMKDRSEL--DLKQSELDKQQTNMN 3796
Query: 1607 EIVSHLESKSRSL-KEHFLREEEDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGE 1431
+I+ ++++ + L K+ EE+ +E+ + + +E+L+ K K
Sbjct: 3797 DIIETMKNERKQLDKDKEEMEEQKREIEKEKHDFDQGRNSLDEDLKMMKLQKQVF----- 3851
Query: 1430 GCEAEKQGLE--KTVLERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCE------AE 1275
E EK LE K LER A + + +EE++ E+ +TE + + AE
Sbjct: 3852 --EEEKNKLEQMKIELEREAGEIRKI----KEEIQNERQSLEKMTEELKREKESFTHLAE 3905
Query: 1274 KQGPEKTVLD-LEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAK--NASLTDNQEGH 1104
E+ +LD ++ SL LQ++ ++ + K+ D++ K N L +++ G
Sbjct: 3906 DTKKEQEILDEIKVANESLMAELQKEKSNFEEMRENISKQTEDVKNKKENLRLREDELG- 3964
Query: 1103 EAEIERKLEASNLTHNDELHKEKDDKKSIMNDLDRVKAEKQVLESKVSDLETTYSTLNNE 924
+L+A E+HK++ + I + +++E+ + V DL+ +L+ +
Sbjct: 3965 ------QLQA-------EIHKQQ---REIEKEKSNIESERAAIIKIVEDLQHKIISLDRD 4008
Query: 923 LQQKMDDNEAFLNERDGLEAVKQGLEK-----------------RVLDLEATIHDIEMKT 795
+ D EAF NER+ L+ +K LE+ RV ++ A I K
Sbjct: 4009 AESLKLDREAFENEREVLKQMKTELERETDEIEKIKLETQHDRQRVEEMTAQITKERDKI 4068
Query: 794 GKDDDYNEAEKQTLKKRISELEEAI-SILTDK--AKKLLKDINIWLSEVTELQEDLNKE- 627
+ + L ++ ++EE I SI +DK +K ++ SE+ +++EDL K+
Sbjct: 4069 NNLIEETNRKDMVLNEKNRDIEEKIKSIQSDKDMLEKEKHNLEKTRSELYKVKEDLEKQK 4128
Query: 626 -------SKEKQDLEKRVLELTSKLEK 567
KE++DLEK +T ++ +
Sbjct: 4129 ENTLAEIQKEREDLEKMNENITIEMHE 4155
Score = 89.0 bits (219), Expect = 2e-14
Identities = 123/538 (22%), Positives = 234/538 (43%), Gaps = 24/538 (4%)
Frame = -3
Query: 2081 QALESKVSVFEAAIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLN 1902
Q +E + E A L E + + ++ I NDR E L+ + D+E + +
Sbjct: 2805 QIIEDERDKIEQIKAELQKEAKDTEKQRQDIENDRRNNEEMVIKLQNEKKDIETSTDRIR 2864
Query: 1901 DE-------LERKKDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXX 1743
DE +R + D + + K+ D + K + +D E + +
Sbjct: 2865 DEEANLRVLKQRLESDRDTLEKERFDLK----KTNTEMKDLEKQLESQNRQHEIQLAEIQ 2920
Query: 1742 XXXKIVSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKE 1563
+I+ L++ + E+L+KE+D D+ E E+ E +
Sbjct: 2921 KEREILEQLKLTLSKQKEDLEKERDCFEKEKADISLRE-------ELQEQSEREGIGKTR 2973
Query: 1562 HFLREEEDEVLE------RSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLE 1401
+++E DE+ + + N + K I E+E K + K+ L + E E +++ +E
Sbjct: 2974 VRIKKEMDELKQTRLNVVKELENNELQKQIIEDERDKIEQIKAELQKEAEDTEKQRRDIE 3033
Query: 1400 K---------TVLERRASNLDT-MDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTV 1251
K L+ +++T D I +EE E V K L + + E E+ EKT
Sbjct: 3034 KDRRNNEEMVIKLQNEKKDIETSTDRIRDEEANLE-VQKQRLESDRDTLEKERFDLEKTK 3092
Query: 1250 LDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIE-RKLEA 1074
++ +L L+ + + + ++K LE +L+ +E E E + + E
Sbjct: 3093 TEM----GNLKKQLESQIRQHEIQLVEIQKEREILEQLKINLSKQKEDLEKERDCFEKEK 3148
Query: 1073 SNLTHNDELHKEKDDKKSIMNDLDRVKAEKQVLESKVSDLETTYSTLNNELQQKMDDNEA 894
++++ +++L KE+ +++ I N R+K E LE +L NNELQ+K+ +
Sbjct: 3149 ADISLSEDL-KEQSEREGIDNTRTRIKQEMDELEKTRQNLAKEQE--NNELQKKIIE--- 3202
Query: 893 FLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISI 714
+ERD +E +K L+K EA +E+ +++ N E T K+ E E+++
Sbjct: 3203 --DERDKIEQIKAELKK-----EAEKTKLEL---QNERQNLEEAGTKLKKDRENVESLAE 3252
Query: 713 LTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLELTSKLEKCICGARDGL 540
+ + +L+++ I TE+Q N+ +K+ Q+ RVL K I GA++ L
Sbjct: 3253 ELGRKQVVLENMQI----ETEMQRKANESNKQMQE---RVLIELKKTVTDIAGAKEDL 3303
Score = 88.2 bits (217), Expect = 3e-14
Identities = 122/534 (22%), Positives = 228/534 (42%), Gaps = 35/534 (6%)
Frame = -3
Query: 2042 IATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAI 1863
I+ L + + NEK+ K ++ L+ Q + K+ D+E KT + E A
Sbjct: 5899 ISKLKEYIDNEKEKSKLREDELKKLQTEVQKQQSKI-DME--KTNIESE--------RAA 5947
Query: 1862 IKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEEL 1683
+ + +++LK + D E M ++ + V NL+ ++ L +
Sbjct: 5948 MIREKQNMMTELKKKS--EDVEIQMKEILTEKELLHNDRKLLTRDVENLQQKLIDLERDS 6005
Query: 1682 QKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVL---ERSASN 1512
++ K D+ A + A + K + +E + R EE ER N
Sbjct: 6006 KRLKLDREAFENEKEAMKQMKTDLQIQADEIEKIKLETQHDRQRVEEMAAQIQKERDKIN 6065
Query: 1511 LAIMKAIREEELRKEKDGK-----SALVENGEGCEAEKQGLEKTV---------LERRAS 1374
I + R++ + EK+ ++ + + E E+ LEKT LE++
Sbjct: 6066 NLIEETNRKDMVLNEKNRDIEEKIKSIQSDKDMLEKERHNLEKTRSELYKVKEDLEKQKE 6125
Query: 1373 NLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKT--VLDLEPTIPSLNDALQRD 1200
N T+ I +E EK++++ E E E+Q +K + L+ I +L L+++
Sbjct: 6126 N--TLAEIQKEREDVEKMNENITREMHEIKHQEEQMNQKQDELDQLKTEIQNLQQELEKE 6183
Query: 1199 LDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIER--KLEASNLTHNDELHKEKDD- 1029
+ +M ++ + R S+L+ + ++ D E + E ++ K + E+ KEK D
Sbjct: 6184 KEIIMKDRSQFDLRQSELDKQQTNMNDIMETMKNERKQLDKDKEEMEEQKQEMEKEKHDF 6243
Query: 1028 ---KKSIMNDLDRVKAEKQVLESKVSDLETTYSTLNNELQQKMDDNEAFLNERDGLEAVK 858
+KS+ DL +K +KQV E + + LE L E + E NER LE +
Sbjct: 6244 DQSRKSLDKDLKMMKLQKQVFEEEKNKLEQMKIELEREADEIRKIKEETQNERQSLEKMT 6303
Query: 857 QGLEKRVLDLEATIHDIEMKTGKDDDY-------NE---AEKQTLKKRISELEEAISILT 708
+ L+K + E+ H E T K+ + NE A+ Q K + E+ E IS T
Sbjct: 6304 EELKK---EKESFTHLAE-DTKKEQEILDKVKVANESLMADLQKEKSNLEEMRENISKQT 6359
Query: 707 DKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLELTSKLEKCICGARD 546
+ + +++ + E+ +LQ ++ K+ +E +EK + + S+ I D
Sbjct: 6360 EDVENKKENLRLREDELWQLQAEIYKQQRE---IEKEKINIESERAAIIKNVED 6410
Score = 87.8 bits (216), Expect = 3e-14
Identities = 125/549 (22%), Positives = 249/549 (45%), Gaps = 43/549 (7%)
Frame = -3
Query: 2027 DELLNEKDDK-----KCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAI 1863
D +LNEK+ K I +D+++LE K LE ++L K ++LE++K++ A
Sbjct: 4079 DMVLNEKNRDIEEKIKSIQSDKDMLEKEKHNLEKTRSELYKVK----EDLEKQKENTLAE 4134
Query: 1862 IKKA---LDKRISDLKADAPQ-RDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILIL 1695
I+K L+K ++ + + + QE+ M + L+ I L
Sbjct: 4135 IQKEREDLEKMNENITIEMHEIKHQEEQMKQ--------------KQDELDQLKTEIQNL 4180
Query: 1694 HEELQKEKD----DKTALIKDLVAAEPGKR--TVNEIVSHLESKSRSL-KEHFLREEEDE 1536
+EL+KEK+ D++ L DL +E K+ +N+I+ ++++ + L K+ EE+ +
Sbjct: 4181 QQELEKEKEIIMKDRSEL--DLRQSELDKQQTNMNDIIETMKNERKLLDKDKEEMEEQKQ 4238
Query: 1535 VLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMD 1356
+E+ N+ +E+L+ K K + E E K L++ E R +T +
Sbjct: 4239 EMEKERDNMDQSIKSLDEDLKMMKLQKQVIEEEKNKLEQMKFELQREADEIRKIKEETQN 4298
Query: 1355 AIHEEELRKEKVDKSALTENGEGCE-AEKQGPEKTVLD-LEPTIPSLNDALQRDLDRVMA 1182
E EK+ K+ + E + AE EK +LD ++ S LQR+ +
Sbjct: 4299 ----ERQSLEKMTKALIKEREDLVHLAEYTKREKEMLDEMQVANKSSMADLQREKRILEE 4354
Query: 1181 EKQALEKRCSDLE---AKNASLTDNQEGHEAEIERK-----LEASNLTHN---------- 1056
++ + K+ D+E K+ D + + E++++ +E +N+
Sbjct: 4355 MRENISKQTEDIENEKEKSKLREDELKKLQTEVQKQQSEIDMEKTNIESERAVMIREKQN 4414
Query: 1055 --DELHKEKDD----KKSIMNDLDRVKAEKQVLESKVSDLETTYSTLNNELQQKMDDNEA 894
EL K+ +D K I+ + + ++ + +L+ + DL+ ++ + + D EA
Sbjct: 4415 MMTELKKKSEDVEIQMKEILTEKELLENDSNLLKKDMEDLKQKLMSIERDSESLKLDREA 4474
Query: 893 FLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISI 714
F NE++ L+ +K L+ + ++E I+++T D E + ++K E+ I +
Sbjct: 4475 FGNEKEVLKQMKTDLQIQADEIE----KIKLETQHDRQRVEEKTAQIQKDRDEINNLI-V 4529
Query: 713 LTDKAKKLLKDINIWLSE-VTELQEDLNKESKEKQDLEKRVLELTSKLEKCICGARDGLS 537
T++ +L +++ + E + +Q D + KE+ +LEK EL A++ L
Sbjct: 4530 ETNRKDMVLNEMDRDIEEKIKSIQSDKDMLEKERHNLEKTRSELAR--------AKENLE 4581
Query: 536 TIKEAWMSD 510
T +E D
Sbjct: 4582 TQREIERKD 4590
Score = 87.0 bits (214), Expect = 6e-14
Identities = 104/492 (21%), Positives = 228/492 (46%), Gaps = 21/492 (4%)
Frame = -3
Query: 2012 EKDDKKCIVNDRNI----LEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKALD 1845
EKD K N++N+ L A + L+ + A++E K L + ++R + + I K+
Sbjct: 2487 EKDRLKLQENEQNMQMSQLNAKQNELDERQAEMEKQKRELENVMDRLEKEKVEITKEK-- 2544
Query: 1844 KRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDD 1665
+R+++++ + +++ D+ + ++E + IL+ EL+K K+
Sbjct: 2545 QRVNEMQNEVKRKNASVDL------------IKQEVLREQDHIENSREILNRELEKIKEK 2592
Query: 1664 KTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNLAIMKAIRE 1485
KT L ++ A + K + + + L L ++E E E+ ++ + E
Sbjct: 2593 KTILAEEFEALDDKKEMIGKEMQRLGKMKAEL------QKEAEDTEKQRRDIDNDRRNNE 2646
Query: 1484 EELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHEEELRKEKVDKSAL 1305
E + K ++ K + + + E+ L + +R S+ DT++ +L K K + L
Sbjct: 2647 EMVIKLQNEKKDIETSTDRIRDEEANL-RVQKQRLESDRDTLEK-ERFDLEKTKTEMKDL 2704
Query: 1304 TENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASL 1125
+ + E Q + + +E I + L++ + +K+ LEK E + A +
Sbjct: 2705 EK-----QLESQSRQHEIQLVE--IQKEREILEQLKINLSKQKEDLEKERDCFEKEKADI 2757
Query: 1124 TDNQEGHEAEIERKLEASNLTHNDELHKEKDDKKSIMNDLDRVKAEKQVLESKVSDLETT 945
+ +E E + ++ + + E+ + + + +++ +L+ + +KQ++E + +E
Sbjct: 2758 SLREELEEQSEKEGIDKTRVRIKQEMDELEQTRLNVVKELENNELQKQIIEDERDKIE-- 2815
Query: 944 YSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTG--KDDDYN- 774
+ ELQ++ D E +R +E ++ E+ V+ L+ DIE T +D++ N
Sbjct: 2816 --QIKAELQKEAKDTE---KQRQDIENDRRNNEEMVIKLQNEKKDIETSTDRIRDEEANL 2870
Query: 773 -------EAEKQTLKKRISELEEAISILTDKAKKL---LKDINIWLSEVTELQEDLNK-- 630
E+++ TL+K +L++ + + D K+L + I L+E+ + +E L +
Sbjct: 2871 RVLKQRLESDRDTLEKERFDLKKTNTEMKDLEKQLESQNRQHEIQLAEIQKEREILEQLK 2930
Query: 629 --ESKEKQDLEK 600
SK+K+DLEK
Sbjct: 2931 LTLSKQKEDLEK 2942
Score = 85.9 bits (211), Expect = 1e-13
Identities = 115/526 (21%), Positives = 234/526 (44%), Gaps = 34/526 (6%)
Frame = -3
Query: 2042 IATLNDELLNEKDDKKCIV----NDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDD 1875
+A L+ EL KD+ + I +R+ +E + L ++ +E + D+ ++
Sbjct: 9987 MADLSRELQKAKDELEKIAYKTNKERHEVEQMQAELHSQIQAIEQQGQIMQDKQNHLEEK 10046
Query: 1874 NNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVN---- 1707
+I +K + +I + + Q +QE N L I N + N
Sbjct: 10047 ELSIQRKEEEIKIGNTEF---QIEQEHLNNVLEETNKRQHDLEVMRADIELNKQKNNKDF 10103
Query: 1706 --ILILHEELQKEKDD--------KTALIKDLVAAEPGKRTVNEIVSHLESK-SRSLKEH 1560
+ + EL+ EK D K + L E K + ++ L+SK ++ KE
Sbjct: 10104 ELLEKIRSELENEKYDLQIWTEQQKHLVEVQLQELEKEKERLEKMEIELQSKREQTEKEK 10163
Query: 1559 FLREEEDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLE--KTVLE 1386
+ ++R + + + + + + K+ L E E + E++ LE K +++
Sbjct: 10164 ADLNRVNAEIQREKQVIDKKRHMTNRAMEELETIKTELKERQEKIQTEQEKLEEEKLLVQ 10223
Query: 1385 RRASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDA-- 1212
A NL+ + + + K ++ ++ L E CE ++ E+ D+E I + +A
Sbjct: 10224 IEAENLNKVLEEIKRQQEKLEISEADLKVMKEQCENAREETERKKCDIEEQIQNNENAKH 10283
Query: 1211 -LQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEI--ERKL--EASN--LTHND 1053
L+++ + +KQ L+K+ DL+ + + +N E + + E+KL + +N L D
Sbjct: 10284 LLEQERKDIDKQKQELQKQADDLDMRMIAHRENVEMSKRSLDEEKKLLEQKANEILRQRD 10343
Query: 1052 ELHKEKDDKKSIMNDLDRVKAEKQVLESKVSDLETTYSTLNNEL---QQKMDDNEAFLNE 882
+L KEK+D N LD ++ E Q + +++ NE+ QQ+++++ +NE
Sbjct: 10344 DLEKEKEDMMKKWNKLDVLQNEMQNENKAMEEIKYELDGKRNEINKEQQRLEESLRAINE 10403
Query: 881 RDG-LEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTD 705
G LE ++ EK+ +E + +M E++ L + SELE+ + +
Sbjct: 10404 EKGDLEIMRADYEKQEQQIEEMRVEAKM-----------ERKELDQIKSELEKDKTEIDY 10452
Query: 704 KAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLELTSKLEK 567
+ KKL D N+ E +L++ ++ ++Q +E EL K+++
Sbjct: 10453 EWKKLNNDRNMIEKERNDLEKMKSELMTQRQQMEDERSELDQKIKE 10498
Score = 85.5 bits (210), Expect = 2e-13
Identities = 111/536 (20%), Positives = 235/536 (43%), Gaps = 46/536 (8%)
Frame = -3
Query: 2072 ESKVSVFEAAIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDEL 1893
E+K ++ E +E+ EK+ ++ R +E ++ +E + LE ++ ++ E
Sbjct: 12356 ETKANILEMKTKAEPEEIKKEKEKEEEEQEMRVKVEMERKEIEQIKSQLERVRSEMDHEQ 12415
Query: 1892 ERKKDDNNAII--KKALDKRISDLKADAPQRDQE-DDMNALIXXXXXXXXXXXXXXKIVS 1722
++ DD I K+ L+K S++ Q ++E +++ I +IV
Sbjct: 12416 KKLNDDKKMIEQEKEDLEKMKSEIMKQRQQMEEERSELDKKIKQTDLEKHDIENSKEIVE 12475
Query: 1721 NLEVNILILHEELQKEK-----------DDKTALIKDLVAAEPGKRTVNEIVSHLESKSR 1575
L V + E+Q +K D++ LI++ + + + E+ ++ +
Sbjct: 12476 KLMVEVEKQKHEIQFQKEELDIERQKIADEQDLLIQNKIEQQNENERIKEMDEEIKKERE 12535
Query: 1574 SLKEHFL-----REEEDEVLE---RSASNLAIMKAIREEELRKEKDGKSALVENGEGCEA 1419
+LKE + +EE + V+E R +L M E+ + + + L + E
Sbjct: 12536 TLKEMEVNLQKEKEEIESVIEETQRRKEDLEKMSTDINEQKQDLMNQRDLLKQ-----ER 12590
Query: 1418 EKQGLEKTVLERRASNLDTMDAI-----------HEEELRKEKVDKSALTENGEGCEAEK 1272
E+ + T L++R +T I +E+L++ + ++ E E
Sbjct: 12591 EEMNHKLTQLQQRIDEFETTSNILVTTKMEEKTEMDEKLQQAIKEYESIIEETNRKRTEL 12650
Query: 1271 QGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEI 1092
+ E + ++ D L+++ E++ L+K+ DLE + D +E + +
Sbjct: 12651 EEIEVDQSQQNKNVETMKDLLEKERKDTEKEREELQKQADDLEMQMIEHGDKEEMSKRSL 12710
Query: 1091 --ERKL--EASN--LTHNDELHKEKDDKKSIMNDLDRVKAEKQVLESKVSDLETTYSTLN 930
E+KL + +N L D+L KEK+D N+LD ++ E Q ++++ +++ T
Sbjct: 12711 DEEKKLLEQKANEILRQRDDLEKEKEDMMKKWNELDGLQKEIQNQKNEMEEIKCELETKR 12770
Query: 929 NELQQKMDDNEAFLN----ERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKD-DDYNEAE 765
E+ ++ E LN ER LE V+ EK + I ++ +KT + D+ ++
Sbjct: 12771 IEIIKEQKRLEESLNTVNEERQYLEIVRVDYEKH----QQQIEEMRVKTKMERDELDQLM 12826
Query: 764 KQTL--KKRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLE 603
+ L +K ++ I +L + ++ +++ ++ EL+ + K EK+DLE
Sbjct: 12827 AKMLMDRKENERSKDMIGLLKKEMEQTKFNLD---AQEEELKLEKQKIQNEKKDLE 12879
Score = 84.7 bits (208), Expect = 3e-13
Identities = 119/558 (21%), Positives = 246/558 (44%), Gaps = 48/558 (8%)
Frame = -3
Query: 2075 LESKVSVFEAAIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDE 1896
L+ + S + +ND + K+++K + D+ E KQ +E + D + ++ +L+++
Sbjct: 5324 LDLRQSELDKQQTNVNDIMETMKNERKQLDKDKEETEEQKQEMEKEKHDFDQSRKSLDED 5383
Query: 1895 LERKKDDNNAII--KKALDKRISDLKADAPQ--RDQEDDMNALIXXXXXXXXXXXXXXKI 1728
L+ K + K L++ +L+ +A + + +E+ N +
Sbjct: 5384 LKMMKLQKQVLEDEKSKLEQMKIELEREAVEIRKIKEEIQNERQNLEKMTEALKEEREDL 5443
Query: 1727 VSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLK--EHFL 1554
+ N +L E + ++++ E + +++ +E+K +L+ E L
Sbjct: 5444 AEETKKNNQVLDEMKVANESTLADILREKSNLEEMRENISKQTEDVENKKENLRLREDEL 5503
Query: 1553 REEEDEV------LERSASNL-----AIMKAIREEELR---KEKDGKSALVENGEGCEAE 1416
R+ + E+ +E+ N+ AI+K + + + + ++D +S ++ E E E
Sbjct: 5504 RQLQAEIHKQQREIEKEKINIESERAAIIKDVEDLQHKIICLDRDAESLKLDR-EAFENE 5562
Query: 1415 KQGLE--KTVLERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCEA----EKQGPEKT 1254
K+ L+ KT LER A ++ + E + +++V++ A + E E+ +
Sbjct: 5563 KEVLKQMKTELEREADEIEKIKL--ETQHDRQRVEEMAAQIQKDRDEINNLIEETNRKDM 5620
Query: 1253 VL-----DLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIE 1089
VL D+E I S+ Q D D + EK LEK S+L L +E AEI+
Sbjct: 5621 VLNEKNRDIEEKIKSI----QSDKDMLEKEKHDLEKTRSELYKVKEDLEKQKENTLAEIQ 5676
Query: 1088 RKLEA-----SNLT-------HNDELHKEKDD-----KKSIMNDLDRVKAEKQVLESKVS 960
++ E N+T H +E +K D K I N ++ EK+++ S
Sbjct: 5677 KEREDLEKMNENITREMHEIKHQEEQMNQKQDELDQLKTEIQNLQQELEKEKEIIMKDRS 5736
Query: 959 DLETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDD 780
L+ S L+ + D E NER L+ K+ +E++ ++E +++ D+
Sbjct: 5737 QLDLRQSELDKQQTNMNDIMETMKNERKQLDKDKEEMEEQKQEMEKERDNMDQSRKSLDE 5796
Query: 779 YNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEK 600
+ +K L+K++ E E+ +K +++ ++ E+++++E+ ++Q LEK
Sbjct: 5797 --DQKKMKLQKQMFEEEK------NKLEQMKIELEREADEISKIKEE---TQNKRQRLEK 5845
Query: 599 RVLELTSKLEKCICGARD 546
EL + E A D
Sbjct: 5846 MTEELIREKESLAHLAED 5863
Score = 84.0 bits (206), Expect = 5e-13
Identities = 103/498 (20%), Positives = 216/498 (43%), Gaps = 12/498 (2%)
Frame = -3
Query: 2075 LESKVSVFEAAIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDE 1896
L+ + S + +ND + K+++K + D+ E KQ +E + D + ++ +L+++
Sbjct: 4647 LDLRQSELDKQQTNMNDIMETMKNERKQLDKDKEETEEQKQEMEKEKHDFDQSRKSLDED 4706
Query: 1895 LERKKDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNL 1716
L+ K + K+ +++ S LK + ++E D + N
Sbjct: 4707 LKMMK-----LQKQVIEEEKSKLKQMKIELEREADEIRKVKEE-------------TQNE 4748
Query: 1715 EVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEED- 1539
+ E L+KE++D +E KR N+++ ++ + S LRE +
Sbjct: 4749 RQIFEKMTEALKKERED---------LSEDAKRK-NQVLDEMKVANESTLADILRERSNL 4798
Query: 1538 -EVLERSASNLAIMKAIREE-ELRKEKDGKSALVENGEGCEAEKQGLEKTVLER-RASNL 1368
E+ E + ++ +E+ LR+EK + + + E EK EK+ +ER RA+ +
Sbjct: 4799 QEMRENISKQTEDVENKKEKIRLREEKLKQLQAEIHKQQSETEK---EKSNIERERAAII 4855
Query: 1367 DTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRV 1188
++ + + + ++ D +L + E E EK+ ++ +LE +++++
Sbjct: 4856 KDVEDLQSKIISLDR-DAESLKLDREAFENEKEELKQMKTELEREAD--------EIEKI 4906
Query: 1187 MAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASNLTHNDELHKEKDDKKSIMND 1008
E Q +R ++ A +N+ + + +++ E H +KS+ +
Sbjct: 4907 KLETQHERQRVEEMTADFMETMNNERKQLNKNKEEMQEQKQEMEKERHDMDQSRKSLDKN 4966
Query: 1007 LDRVKAEKQVLESKVSDLETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDL 828
L +K +KQV+E + + LE L E + E NER LE + + L+K
Sbjct: 4967 LKMMKLQKQVIEEEKNKLEQMKIELEKEADEIRKIKEETQNERQRLEKMTEELKKEKESF 5026
Query: 827 EATIHDI--------EMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLLKDINI 672
D +MK + + +K+ K + E+ E IS T+ ++K + I +
Sbjct: 5027 THLAEDTKTEKKILDKMKVANESLMADLQKE--KSNLEEMRENISKQTEDSEKEKEKIRL 5084
Query: 671 WLSEVTELQEDLNKESKE 618
E+ +LQ +++K+ E
Sbjct: 5085 REDELEQLQAEIHKQQGE 5102
Score = 83.6 bits (205), Expect = 7e-13
Identities = 126/569 (22%), Positives = 237/569 (41%), Gaps = 71/569 (12%)
Frame = -3
Query: 2081 QALESKVSVFEAAIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLN 1902
Q LE + S E L E + + K+ I N+R LE +AL+ + DL N
Sbjct: 5392 QVLEDEKSKLEQMKIELEREAVEIRKIKEEIQNERQNLEKMTEALKEEREDLAEETKKNN 5451
Query: 1901 DELERKKDDNNAIIKKALDKR---------ISDLKADAPQRDQ-----EDDMNALIXXXX 1764
L+ K N + + L ++ IS D + + ED++ L
Sbjct: 5452 QVLDEMKVANESTLADILREKSNLEEMRENISKQTEDVENKKENLRLREDELRQLQAEIH 5511
Query: 1763 XXXXXXXXXXKIVSNLEVNILILHEELQKE----KDDKTALIKDLVAAEPGKRTVNEIVS 1596
+ + I+ E+LQ + D +L D A E K + ++ +
Sbjct: 5512 KQQREIEKEKINIESERAAIIKDVEDLQHKIICLDRDAESLKLDREAFENEKEVLKQMKT 5571
Query: 1595 HLESKSRSLKEHFLREEEDEVL----------ERSASNLAIMKAIREEELRKEKDGK--- 1455
LE ++ +++ L + D +R N I + R++ + EK+
Sbjct: 5572 ELEREADEIEKIKLETQHDRQRVEEMAAQIQKDRDEINNLIEETNRKDMVLNEKNRDIEE 5631
Query: 1454 --SALVENGEGCEAEKQGLEKTV---------LERRASNLDTMDAIHEEELRKEKVDKSA 1308
++ + + E EK LEKT LE++ N T+ I +E EK++++
Sbjct: 5632 KIKSIQSDKDMLEKEKHDLEKTRSELYKVKEDLEKQKEN--TLAEIQKEREDLEKMNENI 5689
Query: 1307 LTENGEGCEAEKQGPEKT--VLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKN 1134
E E E+Q +K + L+ I +L L+++ + +M ++ L+ R S+L+ +
Sbjct: 5690 TREMHEIKHQEEQMNQKQDELDQLKTEIQNLQQELEKEKEIIMKDRSQLDLRQSELDKQQ 5749
Query: 1133 ASLTDNQEGHEAEIER--KLEASNLTHNDELHKEKDD----KKSIMNDLDRVKAEKQVLE 972
++ D E + E ++ K + E+ KE+D+ +KS+ D ++K +KQ+ E
Sbjct: 5750 TNMNDIMETMKNERKQLDKDKEEMEEQKQEMEKERDNMDQSRKSLDEDQKKMKLQKQMFE 5809
Query: 971 SKVSDLETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGL----------------EKR 840
+ + LE L E + E N+R LE + + L EK+
Sbjct: 5810 EEKNKLEQMKIELEREADEISKIKEETQNKRQRLEKMTEELIREKESLAHLAEDTKTEKK 5869
Query: 839 VLDLEATIHDIEMKTGKDDDYNEAEK-----QTLKKRISELEEAISILTDKAKKLLKDIN 675
+LD EMK + + ++ + +++ IS+L+E I +K K L++
Sbjct: 5870 ILD--------EMKVANESSMADLQREKSILEEMRENISKLKEYID--NEKEKSKLRE-- 5917
Query: 674 IWLSEVTELQEDLNKESKEKQDLEKRVLE 588
E+ +LQ ++ K+ + K D+EK +E
Sbjct: 5918 ---DELKKLQTEVQKQ-QSKIDMEKTNIE 5942
Score = 83.2 bits (204), Expect = 9e-13
Identities = 116/555 (20%), Positives = 242/555 (43%), Gaps = 19/555 (3%)
Frame = -3
Query: 1979 RNILEAAKQALEYKVADLEAAKTTLND---ELERKKDDNNAIIKKALDKRISDLKADAPQ 1809
R LE + L+Y ++ K L EL+R+ DD + +K ++R S K
Sbjct: 3455 RTALEVEMKELKYHKQAIQEEKNKLQQMKIELQREADDIKKLKEKTRNERQSLEKMAENL 3514
Query: 1808 RDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHE----ELQKEKDDKTALIKDL 1641
++DD+ L + + +LHE ++QKEK + + + +
Sbjct: 3515 EKEKDDLAHLAED--------------TKRKDDEMKVLHESALADIQKEKCNLEQMRESM 3560
Query: 1640 VAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNLAIMKAIREEE----LR 1473
NE++ E K L+E L++ + E+ R + + K+I E E +
Sbjct: 3561 FKQ-------NEMIDS-EKKKMILREDKLQQMQAEI-NRQQTEMDTKKSIIENERAAMTK 3611
Query: 1472 KEKDGKSALVENGEGCEAEKQGL--EKTVLERRASNLDTMDAIHEEELRKEKVDKSALTE 1299
K +D + L + E E + + + EK +LE L +++L + D +L +
Sbjct: 3612 KNQDLMTELTKQSEDVEIQMKEVLTEKELLESDRKLLKKDVENLQQKLLIIESDSESLKQ 3671
Query: 1298 NGEGCEAEKQGPEKTVLDLE---PTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNAS 1128
+ E E EK+ ++ DL+ I + Q + RV ++K L+ N +
Sbjct: 3672 DRELLENEKEVLKQMKTDLQGEAEEIEKIKLETQHERQRVEEMTAQIQKDREYLQKMNDN 3731
Query: 1127 LTDNQEGHEAEIERKLEASNLTHNDELHKEKDDKKSIMNDLDRVKAEKQVLESKVSDLET 948
+T +E H+ + + K DEL + K + +++ +L++ EK+++ S+L+
Sbjct: 3732 IT--REIHDIKYQEKQMKQK---QDELDQLKTEIQNLQQELEK---EKEIIMKDRSELDL 3783
Query: 947 TYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEM-KTGKDDDYN- 774
S L+ + D E NER L+ K+ +E++ ++E HD + + D+D
Sbjct: 3784 KQSELDKQQTNMNDIIETMKNERKQLDKDKEEMEEQKREIEKEKHDFDQGRNSLDEDLKM 3843
Query: 773 -EAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKR 597
+ +KQ ++ ++LE+ + I ++ ++ I + + E + +E K +++
Sbjct: 3844 MKLQKQVFEEEKNKLEQ-MKIELEREAGEIRKIKEEIQNERQSLEKMTEELKREKESFTH 3902
Query: 596 VLELTSKLEKCICGARDGLSTIKEAWMSDCMVPDNWVPFEDLVQGFSRKTSPLDITKTCD 417
+ E T K ++ + D + E+ M++ + FE++ + S++T D+ +
Sbjct: 3903 LAEDTKKEQEIL----DEIKVANESLMAELQKEKS--NFEEMRENISKQTE--DVKNKKE 3954
Query: 416 AVDISEDSTTNIQVD 372
+ + ED +Q +
Sbjct: 3955 NLRLREDELGQLQAE 3969
Score = 81.3 bits (199), Expect = 3e-12
Identities = 112/514 (21%), Positives = 217/514 (42%), Gaps = 22/514 (4%)
Frame = -3
Query: 2042 IATLNDELLNEKDDKKC-----------IVNDRNILEAAKQALEYKVADLEAAKTTLNDE 1896
I+ +++ NEK+ K + ++ ++ K +E + A + K + E
Sbjct: 4359 ISKQTEDIENEKEKSKLREDELKKLQTEVQKQQSEIDMEKTNIESERAVMIREKQNMMTE 4418
Query: 1895 LERKKDDNNAIIKKAL-DKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSN 1719
L++K +D +K+ L +K + + ++ ++D ED L+ +
Sbjct: 4419 LKKKSEDVEIQMKEILTEKELLENDSNLLKKDMEDLKQKLMSIERDSESLKLDREAFGNE 4478
Query: 1718 LEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEED 1539
EV + + +LQ + D+ + K + + ++ V E + ++ K R E +
Sbjct: 4479 KEV-LKQMKTDLQIQADE---IEKIKLETQHDRQRVEEKTAQIQ-KDRD-------EINN 4526
Query: 1538 EVLERSASNLAIMKAIR--EEELRKEKDGKSALVENGEGCEAEKQGLEKT--VLERRASN 1371
++E + ++ + + R EE+++ + K L E E+ LEKT L R N
Sbjct: 4527 LIVETNRKDMVLNEMDRDIEEKIKSIQSDKDML-------EKERHNLEKTRSELARAKEN 4579
Query: 1370 LDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDR 1191
L+T I +++ K K + S + E + + + + L+ I +L L+++ +
Sbjct: 4580 LETQREIERKDIEKMKKNISREMHEIKHQEEQMKQKQDELDQLKTEIQNLQQELEKEKEI 4639
Query: 1190 VMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIER--KLEASNLTHNDELHKEKDD---- 1029
+M + L+ R S+L+ + ++ D E + E ++ K + E+ KEK D
Sbjct: 4640 IMKARSQLDLRQSELDKQQTNMNDIMETMKNERKQLDKDKEETEEQKQEMEKEKHDFDQS 4699
Query: 1028 KKSIMNDLDRVKAEKQVLESKVSDLETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGL 849
+KS+ DL +K +KQV+E + S L+ L E + E NER E + + L
Sbjct: 4700 RKSLDEDLKMMKLQKQVIEEEKSKLKQMKIELEREADEIRKVKEETQNERQIFEKMTEAL 4759
Query: 848 EKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIW 669
+K DL D + K D+ A + TL DI
Sbjct: 4760 KKEREDLS---EDAKRKNQVLDEMKVANESTLA----------------------DI--- 4791
Query: 668 LSEVTELQEDLNKESKEKQDLEKRVLELTSKLEK 567
L E + LQE SK+ +D+E + ++ + EK
Sbjct: 4792 LRERSNLQEMRENISKQTEDVENKKEKIRLREEK 4825
Score = 80.9 bits (198), Expect = 4e-12
Identities = 119/523 (22%), Positives = 221/523 (42%), Gaps = 20/523 (3%)
Frame = -3
Query: 2075 LESKVSVFEAAIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDE 1896
L++ S E + +L E N +D+K + R+ + + A+ + DLE + E
Sbjct: 9663 LQNMKSNLERQLESLRHEKANVEDEKNALEKMRSESKEIQNAIRKEREDLENCWVEIEGE 9722
Query: 1895 LERKKDDNNAI------IKKALDKRISDLKADAPQRDQE--DDMNALIXXXXXXXXXXXX 1740
+R +++ + IKK +D + + + R+++ + M L+
Sbjct: 9723 KKRMEEETRRLEMHREEIKK-VDSELQKSRENIESREEKINNKMEELLQMKVEMGRTKEE 9781
Query: 1739 XXKIVSNLEVNILILHE---ELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSL 1569
K L+ + L E+Q++ +DK I D+ E + EI L+ +++ L
Sbjct: 9782 IEKESQRLQDATIDLENAKAEIQRQ-EDKFEDIIDIKIQEKER----EIKIQLDKETKRL 9836
Query: 1568 KEHFLREEEDEVLE-----RSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGL 1404
E + +D +E R + K + E+E ++ K K L + EKQ
Sbjct: 9837 SEEIELKVKDLEMEMADMKRQKQEIEDTKGLLEKEKQELKQEKKELEDQMMDLTREKQET 9896
Query: 1403 EKTVLERRASNLDTMDAIHEEELRKEKV--DKSALTENGEGCEAEKQGPEKTVLDLEPTI 1230
E+ A D E E+ KEK+ +KS + E +++ ++T + +
Sbjct: 9897 EEERNNLMALKNQLEDLRKENEIVKEKLTLEKSNIEEMQLKIFKQQRLNDQTREENKKE- 9955
Query: 1229 PSLNDALQRDLDRVMAEKQALEKRCSDL-EAKNASLTDNQEGHEAEIERKLEASNLTHND 1053
++L++ +KQ LE + + E KN ++E +A+ E LE N
Sbjct: 9956 ---KESLEQQRFETEQQKQMLEISTTKMMEEKNEMADLSRELQKAKDE--LEKIAYKTNK 10010
Query: 1052 ELHKEKDDKKSIMNDLDRVKAEKQVLESKVSDLETTYSTLNNELQQKMDDNEAFLNERDG 873
E H+ + + + + + ++ + Q+++ K + LE ++ + ++ N F E++
Sbjct: 10011 ERHEVEQMQAELHSQIQAIEQQGQIMQDKQNHLEEKELSIQRKEEEIKIGNTEFQIEQEH 10070
Query: 872 LEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKK 693
L V + KR DLE DIE+ K N + + L+K SELE
Sbjct: 10071 LNNVLEETNKRQHDLEVMRADIELNKQK----NNKDFELLEKIRSELENE---------- 10116
Query: 692 LLKDINIWLSEVTELQE-DLNKESKEKQDLEKRVLELTSKLEK 567
D+ IW + L E L + KEK+ LEK +EL SK E+
Sbjct: 10117 -KYDLQIWTEQQKHLVEVQLQELEKEKERLEKMEIELQSKREQ 10158
Score = 80.1 bits (196), Expect = 7e-12
Identities = 122/570 (21%), Positives = 236/570 (41%), Gaps = 68/570 (11%)
Frame = -3
Query: 2075 LESKVSVFEAAIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLE--AAKTTLN 1902
+E+K + L D+ + K+D+ D LE ++ L + DLE +
Sbjct: 9479 METKKRSLDRMSRELQDDKIRLKNDRDAYEKDMTHLELKREELVRETEDLERKILQQREQ 9538
Query: 1901 DELERKKDDNNA---------IIKK-----------------------ALDKRISDLKAD 1818
DE+ ++ +N I+KK AL + S+L+
Sbjct: 9539 DEMAKRDIENQTEALEVMKVDILKKRNEFAKEMENVHSERQKLLLLQGALQSQESELENR 9598
Query: 1817 APQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDKTALIKDLV 1638
+Q+ A + + + L EELQ+EK ++ + K+ +
Sbjct: 9599 VFMEEQKHLKQAKAETEECRKQLAEMSETVTTE-QNEYRKLIEELQREK-EQLEISKNQI 9656
Query: 1637 AAEPGKRTVNEIVSHLESKSRSLK-EHFLREEEDEVLERSAS-NLAIMKAIREEELRKEK 1464
E K+ + + S+LE + SL+ E E+E LE+ S + I AIR+E
Sbjct: 9657 EQE--KKDLQNMKSNLERQLESLRHEKANVEDEKNALEKMRSESKEIQNAIRKER----- 9709
Query: 1463 DGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHEEELRKEKVDKSALTENGEGC 1284
E+ E C E +G EK +E L+ +H EE++K + EN E
Sbjct: 9710 -------EDLENCWVEIEG-EKKRMEEETRRLE----MHREEIKKVDSELQKSRENIESR 9757
Query: 1283 EAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTD----N 1116
E + + +L ++ + + ++++ R+ LE ++++ + D
Sbjct: 9758 EEKINNKMEELLQMKVEMGRTKEEIEKESQRLQDATIDLENAKAEIQRQEDKFEDIIDIK 9817
Query: 1115 QEGHEAEIERKLEASNLTHNDELHKEKDDKKSIMNDLDRVKAE----KQVLESKVSDLET 948
+ E EI+ +L+ ++E+ + D + M D+ R K E K +LE + +L+
Sbjct: 9818 IQEKEREIKIQLDKETKRLSEEIELKVKDLEMEMADMKRQKQEIEDTKGLLEKEKQELKQ 9877
Query: 947 TYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLE---------KRVLDLE-ATIHDIEMK 798
L +++ + + ER+ L A+K LE K L LE + I ++++K
Sbjct: 9878 EKKELEDQMMDLTREKQETEEERNNLMALKNQLEDLRKENEIVKEKLTLEKSNIEEMQLK 9937
Query: 797 TGKDD-------DYNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQED 639
K + N+ EK++L+++ E E+ +L K++++ N ELQ+
Sbjct: 9938 IFKQQRLNDQTREENKKEKESLEQQRFETEQQKQMLEISTTKMMEEKNEMADLSRELQKA 9997
Query: 638 LN-------KESKEKQDLEKRVLELTSKLE 570
+ K +KE+ ++E+ EL S+++
Sbjct: 9998 KDELEKIAYKTNKERHEVEQMQAELHSQIQ 10027
Score = 79.3 bits (194), Expect = 1e-11
Identities = 93/521 (17%), Positives = 226/521 (43%), Gaps = 46/521 (8%)
Frame = -3
Query: 1991 IVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKALDKR--------- 1839
++N R++L+ ++ + +K L+ + ++ ++K+++ KK ++R
Sbjct: 12024 LMNQRDLLKQEREEINHKWTQLQQRIDEFDAQVSKQKEEDLTKQKKMEEERKSLEETKIK 12083
Query: 1838 ISDLKADAP--------QRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEEL 1683
I ++K ++++E+ M A + I S LE + E
Sbjct: 12084 IIEMKTKTEPEKIKKEKEKEEEEVMRAKVEMKKEELDQ------IKSQLERVRSEIDHEQ 12137
Query: 1682 QKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNLAI 1503
+K DDK + ++ E K + + +E + RS E+ +R+ E + S +
Sbjct: 12138 KKLNDDKKMIEQEKEDLEKMKSEIMKQRQQMEEE-RSELENKIRQTYIEKCDIENSKEIV 12196
Query: 1502 MKAIREEELRKEK----------------DGKSALVENGEGCEAEKQGLEKT--VLERRA 1377
K + E E +K + D + L++N + E + ++ V+++
Sbjct: 12197 QKLMVEVEEQKHEIQFQKEELDIERQKIADEQDLLIQNKSELQNENERIKNINEVIKKER 12256
Query: 1376 SNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDL 1197
L M+A L KEK + ++TE + + + + + + + S D L+++
Sbjct: 12257 ETLKEMEAY----LEKEKEEMKSITEETRRQKEDLEKMSTHINEQKQDLRSQRDLLEQER 12312
Query: 1196 DRVMAEKQALEKRCSDLEA-----------KNASLTDNQEGHEAEIERKLEASNLTHNDE 1050
+ + + + L++R + +A K + ++++ E LE +E
Sbjct: 12313 EEINHKWKQLQQRIDEFDAQVSKQKEEDLPKEKEMKEDRKSLEETKANILEMKTKAEPEE 12372
Query: 1049 LHKEKDDKKSIMNDLDRVKAEKQVLESKVSDLETTYSTLNNELQQKMDDNEAFLNERDGL 870
+ KEK+ ++ +V+ E++ +E S LE S +++E ++ DD + E++ L
Sbjct: 12373 IKKEKEKEEEEQEMRVKVEMERKEIEQIKSQLERVRSEMDHEQKKLNDDKKMIEQEKEDL 12432
Query: 869 EAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKL 690
E +K + K+ +E +++ K K D + + + K+ + +L + + +
Sbjct: 12433 EKMKSEIMKQRQQMEEERSELDKKI-KQTDLEKHDIENSKEIVEKLMVEVEKQKHEIQFQ 12491
Query: 689 LKDINIWLSEVTELQEDLNKESKEKQDLEKRVLELTSKLEK 567
++++I ++ + Q+ L + E+Q+ +R+ E+ +++K
Sbjct: 12492 KEELDIERQKIADEQDLLIQNKIEQQNENERIKEMDEEIKK 12532
Score = 79.0 bits (193), Expect = 2e-11
Identities = 115/572 (20%), Positives = 246/572 (43%), Gaps = 91/572 (15%)
Frame = -3
Query: 2027 DELLNEKDDKKCIVND----RNILEAAKQALEYKVADLEAAKTTLND----------ELE 1890
+EL E+ D + D +N L+ K A E +ADL+ K+ L + ++E
Sbjct: 6721 EELKKERKDVAHLAEDTKREKNSLDEMKVANESSMADLQKEKSNLEEMKENISKQTEDIE 6780
Query: 1889 RKKD------DNNAIIKKALDKRISDLKADAPQRDQE--------DDMNALIXXXXXXXX 1752
++KD D ++ + K+ S+ + + ++E +D+ + I
Sbjct: 6781 KEKDKIRLREDELEQLQAEIHKQQSETEIEKSNIERERAAIIKDVEDLQSKIISLDRDAE 6840
Query: 1751 XXXXXXKIVSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSH----LES 1584
+ N + + + EL++E D+ + K + + ++ V E+ + + +
Sbjct: 6841 SLKLDREAFENEKEELKQMKTELEREADE---IEKIKLETQHERQRVEEMTADFMETMNN 6897
Query: 1583 KSRSL-KEHFLREEEDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQG 1407
+ + L K + EE+ + +E+ ++ + +E+L+ K K L E E K G
Sbjct: 6898 ERKQLDKNKVMIEEQKQEMEKKRDDMDQSRKSLDEDLKMMKAQKQVLEEEKNKLEQMKIG 6957
Query: 1406 LE---------KTVLERRASNLDTM-DAIHEE------ELRKEKVDKSALTENGEGCEAE 1275
LE K + NL+ M +A+ EE E++++ + E A+
Sbjct: 6958 LEREADEISKIKEETQNERQNLEKMANALKEEREYLAEEIKRKNQVLDKIKVANESTLAD 7017
Query: 1274 KQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAE 1095
Q ++ + ++ I + ++ + ++ + L+K ++++ + + + + E+E
Sbjct: 7018 LQKEKRILEEMRENISKQIEDIENEKEKSKLREDELKKLQTEVQKQQSEIDMEKTNIESE 7077
Query: 1094 IERKL-EASNLTHNDELHKEKDD----KKSIMNDLDRVKAEKQVLESKVSDLETTYSTLN 930
+ E N+ EL K+ +D K I+ + + + ++ +L+ V DL+ ++
Sbjct: 7078 RAAMIREKQNMM--TELKKKSEDVEMQMKEILTEKELLHNDRNLLKKDVEDLQQKLMSIE 7135
Query: 929 NELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLE----ATIHD---IEMKTGK------ 789
+ + D EAF NE++ ++ +K L+ + ++E T H+ +E KT +
Sbjct: 7136 RDSESLKLDKEAFENEKEAMKQMKTDLQIQADEIEKIKLETHHERQRVEEKTAQIQKERE 7195
Query: 788 ----------------DDDYNE--AEKQTLKKRISELEEAISILTDKAKKLLKDINIWLS 663
D+ Y E EK+ ++ S+LE+A S + K K+I I L+
Sbjct: 7196 EINTLVEEIKKKRDIIDESYTEIRKEKEAIESDRSDLEKAKS----QTFKQNKNIEIALA 7251
Query: 662 EVTELQEDLNKESKE------KQDLEKRVLEL 585
E+ + + L K SKE K + EK+ ++L
Sbjct: 7252 EIQQKRNALEKMSKEISRDRMKLEDEKKEIQL 7283
Score = 78.6 bits (192), Expect = 2e-11
Identities = 134/578 (23%), Positives = 246/578 (42%), Gaps = 76/578 (13%)
Frame = -3
Query: 2072 ESKVSVFEAAIATLNDELLNEKDD---KKCIVNDR-NILEAAKQALEYKVADLEAAKTTL 1905
+ K+ + EA + + ++ N +++ KKC + ++ E AK LE + D++ K
Sbjct: 10240 QEKLEISEADLKVMKEQCENAREETERKKCDIEEQIQNNENAKHLLEQERKDIDKQK--- 10296
Query: 1904 NDELERKKDD----------NNAIIKKALD--KRISDLKADAPQRDQEDDMNALIXXXXX 1761
EL+++ DD N + K++LD K++ + KA+ R ++D +
Sbjct: 10297 -QELQKQADDLDMRMIAHRENVEMSKRSLDEEKKLLEQKANEILRQRDD-----LEKEKE 10350
Query: 1760 XXXXXXXXXKIVSNLEVNILILHEELQKEKDDKTALI-KDLVAAEPGKRTVNEIVSHLES 1584
++ N N EE++ E D K I K+ E R +NE LE
Sbjct: 10351 DMMKKWNKLDVLQNEMQNENKAMEEIKYELDGKRNEINKEQQRLEESLRAINEEKGDLEI 10410
Query: 1583 KSRSLKEHFLREEEDEV--------LERSASNLAIMKAIREEELRKEKDGKSALVENGEG 1428
++ + EE V L++ S L K + E +K + ++ + +
Sbjct: 10411 MRADYEKQEQQIEEMRVEAKMERKELDQIKSELEKDKTEIDYEWKKLNNDRNMIEKERND 10470
Query: 1427 CEAEKQGL--EKTVLERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKT 1254
E K L ++ +E S LD I E K+K++K+ E E+Q +
Sbjct: 10471 LEKMKSELMTQRQQMEDERSELD--QKIKEANTEKDKIEKNKEIVERLMAEVEEQRNDFK 10528
Query: 1253 VLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEG--HEAEIERKL 1080
+ E + N ++ EK L + ++L+ K+ + + +E +E E ++
Sbjct: 10529 LKKEELALERQN---------IVDEKYLLAQCETELQNKSEQIRNMEEAVKNERETLKET 10579
Query: 1079 EASNLTHNDELHKEKDDKKSIMNDLDRVK-----------AEKQVLESKVSDLETTYSTL 933
EA L ++K + KSI+ + R K +KQ L++K LE +
Sbjct: 10580 EA-------HLQRDKKEIKSIIEETSRQKEDLEKISTGMNVQKQELKNKKDTLEQEREEI 10632
Query: 932 NN---ELQQKMDDNEAFLN---ERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNE 771
N+ + QQ++D+ +A + E D K E++ L+ E IEMKT + +++E
Sbjct: 10633 NHKWTQFQQRIDEFDAQVRKQKEEDLTNQKKMEEERKCLE-EVNGKIIEMKTKAELEHHE 10691
Query: 770 A-----EKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEV----TEL---------- 648
E QTL+++I + +E +T K K +D++ SE+ TE+
Sbjct: 10692 INQKIEELQTLQEQIMKEKEKAEAMTIKLKMEREDLDQIKSELVREKTEVDHEQKKLNDD 10751
Query: 647 -------QEDLNKESKE----KQDLEKRVLELTSKLEK 567
+EDL K E KQ++EK EL +K+++
Sbjct: 10752 IKMIEQEKEDLEKMKSEIMTQKQEMEKERSELDNKIQQ 10789
Score = 77.0 bits (188), Expect = 6e-11
Identities = 108/541 (19%), Positives = 221/541 (40%), Gaps = 58/541 (10%)
Frame = -3
Query: 2042 IATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAI 1863
IA + D+LL EK+D +E K+ + + +E ++ LND+ E +N +
Sbjct: 13675 IADMKDQLLKEKED----------VETTKERINREKEHIEKMQSQLNDQKEEMDLENQKL 13724
Query: 1862 I---------KKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEV 1710
+ AL+K + DL+ + +++NAL+ E
Sbjct: 13725 LYMKTEIQVKTNALEKMMQDLQKE------RENVNALVIQHQ-------------KEREQ 13765
Query: 1709 NILILHEELQKEKDDKTALIKDLVAAEPGK-------RTVNEIVSHLESKSRSLKEHFLR 1551
+++ E +KEK + + + E K ++++ S L+++S L E+ ++
Sbjct: 13766 RDILIEENKRKEKHAEAEIQRQFEDIESVKVRLVTESNQIDKMNSELKTRSEEL-ENLIK 13824
Query: 1550 EEEDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASN 1371
+++ E + KA+ E++ E + KS ++N + EK + + L++ +
Sbjct: 13825 KQQKEFETKENEMQRERKAL--EKMNAELERKSTELKN----KIEKVTVWEADLQKEKNK 13878
Query: 1370 LDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDR 1191
+ + I E E + +K+ + + E ++ + + +LE L D + L R
Sbjct: 13879 TEELKNILEREKSELYQEKAQVQQQKHEMETIRKTMKSEMENLECLRNELEDEKKSMLSR 13938
Query: 1190 VMAEKQALEKRCSDLEAKNAS----------LTDNQEGHEAEIERKLEASNLTHNDELHK 1041
+ EK ++K ++++++ S L D E +++ +E N+ + +
Sbjct: 13939 LSMEKHEIDKLKTEIQSEKESIEEEKKTLKQLKDENESKRTQLDNTIEKMNMDKLS-IQR 13997
Query: 1040 EKDDKKSIMNDLDRVKAEK-----------------------------QVLESKVSDLET 948
EKD + I DL R KAEK + L S +D+E
Sbjct: 13998 EKDSLEEIKADLQR-KAEKLDEEMRKAVQITSQISQDAKILDDDREKEEELRSMRADIER 14056
Query: 947 TYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEA 768
L +++Q L+ K+ LEK + + D+E K N+
Sbjct: 14057 QAKILESDVQL--------------LQTEKEILEKSKTENDLLREDLE----KQRKRNDL 14098
Query: 767 EKQTLKKRISELEEAISILT---DKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKR 597
Q L+K LE+ I+ +T D L ++++ E+ + +L+++ KE DL +
Sbjct: 14099 TLQELRKEKMALEQMITDITKEKDAVASLQNEVSLKQHELKNKETELDEQRKEMDDLRMQ 14158
Query: 596 V 594
+
Sbjct: 14159 L 14159
Score = 75.5 bits (184), Expect = 2e-10
Identities = 117/561 (20%), Positives = 241/561 (42%), Gaps = 56/561 (9%)
Frame = -3
Query: 2081 QALESKVSVFEAAIATLNDELLNEK----DDKKCIVNDRNILEAAKQALEYKVADLEAAK 1914
Q + ++ + IA D L+ K ++ + I N +++ ++ L+ A LE K
Sbjct: 10819 QLQKEELDIERQKIADEQDLLIQNKSELQNENERIRNINEVIKKERETLKEMEAHLEKEK 10878
Query: 1913 T---TLNDELERKKDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXX 1743
++ +E R+K+D L+K +D+K ++ D+ L
Sbjct: 10879 EEMKSITEETRRQKED--------LEKMSTDIKEQNQDLMKQRDL--LEQEKEDINHEWT 10928
Query: 1742 XXXKIVSNLEVNILILHEE---LQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRS 1572
+ + + + EE QKE ++ +++ A +T E+ + K +
Sbjct: 10929 QLQQRIDEFDAQVSKQKEEDLTKQKEMKEERKSLEETKARIIEMKTKAELEDIKKEKEKE 10988
Query: 1571 LKEHFLR---EEEDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLE 1401
+E +R E + + L+R S L ++ + E +K D K + E EKQ LE
Sbjct: 10989 EEEEEMRVKVEMDGKELDRIKSELKRERSEIDHEQKKLNDDKKII-------EQEKQNLE 11041
Query: 1400 KTVLERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPT---I 1230
K ++ + + EE E K E + E K+ +K ++++E I
Sbjct: 11042 KM----KSEIMKQRQQMEEERSELENKIKQTYIEKCD-IENSKEIVQKLMVEVEEQKHEI 11096
Query: 1229 PSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQE--GHEAEIERKLEASNLTHN 1056
+ L + ++ E+ L + S+L+ +N + + E E E +++EA
Sbjct: 11097 QFQKEELDIERQKIADEQDLLIQNKSELQNENERIRNLNEIIKKERETLKEMEA------ 11150
Query: 1055 DELHKEKDDKKSIMNDLDRVKAEKQVLESKVSD-----------LETTYSTLNN---ELQ 918
L K+K++ KS+ + R+K + + + + V+ LE +N+ +LQ
Sbjct: 11151 -HLEKKKEEIKSVSEETRRLKEDLEKMSTDVNKQNKDLMNQRDLLEQEREEINHKWKQLQ 11209
Query: 917 QKMDDNEAFLNERDGLEAVKQ-GLEKRVLDLEAT-IHDIEMKTGKDDDYNEAEKQTLKKR 744
Q++D+ +A ++++ + K+ G+++ LE T + IEMKT + + + EK+ +
Sbjct: 11210 QRIDEFDAQVSKQKEQDLPKEKGMKEDRKSLEETKANVIEMKTKAEPEEIKKEKEKENEE 11269
Query: 743 ISELEEAISILTDKAKKLL------------------KDINIWLSEVTELQEDLNKES-- 624
E EE I ++ + +K L K +N ++ + + +EDL K
Sbjct: 11270 EEEEEEEIRVIVETERKELYQIKSELERVRSEIDHEQKKLNDYMKMIEQEKEDLEKMKSE 11329
Query: 623 --KEKQDLEKRVLELTSKLEK 567
K++Q +E+ EL +K+++
Sbjct: 11330 IMKQRQQMEEERSELDNKIQQ 11350
Score = 75.1 bits (183), Expect = 2e-10
Identities = 111/513 (21%), Positives = 212/513 (41%), Gaps = 67/513 (13%)
Frame = -3
Query: 1904 NDELERKKDD-NNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKI 1728
ND +E+ ++D NNA+ K +D+ D++ QE A++ I
Sbjct: 1457 NDRVEQMREDVNNAL--KDIDQAKEDIQRQREVIAQEKVQPAIVATKSSEYAKTEEPGAI 1514
Query: 1727 VSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLRE 1548
S + L L +QKE+ + K+++ E K +N+I +++ +E ++
Sbjct: 1515 KS-YRASDLELSASIQKERQELEHY-KEIILKE--KHELNKIKEDVKAVKNDAEERMIKL 1570
Query: 1547 EEDEVLERSASNLAIMKAIREEELRKEKD--GKSALVENGEGCEAEKQGL---------E 1401
E+E E +++ R+ + KEK+ G A+ + KQ L E
Sbjct: 1571 HEEEK-EMKTKRVSLQNWERQLQTEKEKNQKGLDAIWNENQQLNERKQQLDIKELHLQSE 1629
Query: 1400 KTVLERR-------------------ASNLDTMDAIHEEELRKEKVDKSALTENGEGCEA 1278
K+ LE + AS D +I E + +++ ++ + C
Sbjct: 1630 KSKLEYKKPLEIKQVDAQVQTELMEDASEYDMALSIEELDKQRQFLEYFKQELLAQKCTM 1689
Query: 1277 EKQGPE-------------------KTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRC 1155
E+Q E +T D+E + L++ D + K ++K
Sbjct: 1690 ERQMAEIELSRDELSLREATLQTATQTTADMELQLELQKQELEQTKDEMERTKLEVQKGW 1749
Query: 1154 SDLEAKNASLTDNQEGHEAEIERKLEASNLTHND-ELHK---EKDDKKSIMNDLDRVKAE 987
DL+ + A + +E E+E+ + N D E K E D K ++ + + ++A+
Sbjct: 1750 VDLQTQIAESREKEEMVRIELEKARDVLNRIRQDVETEKQTMEADLKFTLAKEFENLEAQ 1809
Query: 986 KQVLESKVSDLETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDI 807
++++E + LE L E +ER +E + L++ +LE HD+
Sbjct: 1810 RKMMEDEKRALENMKYELQRESGYIERSKHNMHDERQNMENWAEKLKQEWEELEKKRHDM 1869
Query: 806 EM------KTGKD-DDYNEAEKQTLK--KRISELEEAISILTDKAKKLLKD----INIWL 666
+ + KD ++ E + TL K S++ E IS L + K +++ I I
Sbjct: 1870 QQLQTERSREIKDLENLRELNELTLNQIKTKSDVLEKISELNSQQKDEIENEKSKIKIRE 1929
Query: 665 SEVTELQEDLNKESKEKQDLEKRVLELTSKLEK 567
++ ++Q DLN++ KE QD++ V S+L+K
Sbjct: 1930 YDLQQMQTDLNRQQKEMQDIQNAVFMEKSELKK 1962
Score = 73.6 bits (179), Expect = 7e-10
Identities = 118/540 (21%), Positives = 235/540 (43%), Gaps = 37/540 (6%)
Frame = -3
Query: 2075 LESKVSVFEAAIATLN-DELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLND 1899
LE + FE A ++ E L E+ +K+ I D+ + ++ E + L K N+
Sbjct: 2743 LEKERDCFEKEKADISLREELEEQSEKEGI--DKTRVRIKQEMDELEQTRLNVVKELENN 2800
Query: 1898 ELERK--KDDNNAI--IKKALDKRISDLKADAPQRDQEDDMN---ALIXXXXXXXXXXXX 1740
EL+++ +D+ + I IK L K D + ++D E+D ++
Sbjct: 2801 ELQKQIIEDERDKIEQIKAELQKEAKD--TEKQRQDIENDRRNNEEMVIKLQNEKKDIET 2858
Query: 1739 XXKIVSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEH 1560
+ + E N+ +L + L+ ++D L K+ + + ++ LES++R +
Sbjct: 2859 STDRIRDEEANLRVLKQRLESDRD---TLEKERFDLKKTNTEMKDLEKQLESQNRQHEIQ 2915
Query: 1559 FLR-EEEDEVLERSASNLAIMKAIREEE---LRKEKDGKSALVENGEGCEAEKQGLEKTV 1392
++E E+LE+ L+ K E+E KEK S E E ++E++G+ KT
Sbjct: 2916 LAEIQKEREILEQLKLTLSKQKEDLEKERDCFEKEKADISLREELQE--QSEREGIGKT- 2972
Query: 1391 LERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDA 1212
R MD EL++ +++ EN E +KQ
Sbjct: 2973 ---RVRIKKEMD-----ELKQTRLNVVKELENNE---LQKQ------------------I 3003
Query: 1211 LQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASNLTHNDELHKEKD 1032
++ + D++ K L+K D E + + ++ +E E+ KL+ + +D
Sbjct: 3004 IEDERDKIEQIKAELQKEAEDTEKQRRDIEKDRRNNE-EMVIKLQNEKKDIETSTDRIRD 3062
Query: 1031 DKKSIMNDLDRVKAEKQVLESKVSDLETTYSTLNN---ELQQKMDDNEAFL----NERDG 873
++ ++ R+++++ LE + DLE T + + N +L+ ++ +E L ER+
Sbjct: 3063 EEANLEVQKQRLESDRDTLEKERFDLEKTKTEMGNLKKQLESQIRQHEIQLVEIQKEREI 3122
Query: 872 LEAVKQGLEKRVLDLEATIHDIEMKTG----KDDDYNEAEKQ-------TLKKRISELEE 726
LE +K L K+ DLE E + +D ++E++ +K+ + ELE+
Sbjct: 3123 LEQLKINLSKQKEDLEKERDCFEKEKADISLSEDLKEQSEREGIDNTRTRIKQEMDELEK 3182
Query: 725 AISIL------TDKAKKLLKDINIWLSEV-TELQEDLNKESKEKQDLEKRVLELTSKLEK 567
L + KK+++D + ++ EL+++ K E Q+ + + E +KL+K
Sbjct: 3183 TRQNLAKEQENNELQKKIIEDERDKIEQIKAELKKEAEKTKLELQNERQNLEEAGTKLKK 3242
Score = 73.2 bits (178), Expect = 9e-10
Identities = 128/570 (22%), Positives = 246/570 (43%), Gaps = 69/570 (12%)
Frame = -3
Query: 2072 ESKVSVFEAAIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDEL 1893
+ ++ + I L EL EK+ I+ DR+ L+ + ++L+ +T +ND +
Sbjct: 4167 QDELDQLKTEIQNLQQELEKEKE---IIMKDRS-------ELDLRQSELDKQQTNMNDII 4216
Query: 1892 ERKKDDNNAIIKKALDKRISDLKADAPQRDQE-DDMNALIXXXXXXXXXXXXXXKIVSNL 1716
E K++ +K LDK +++ + ++E D+M+ I +++
Sbjct: 4217 ETMKNE-----RKLLDKDKEEMEEQKQEMEKERDNMDQSIKSLDEDLKMMKLQKQVIEEE 4271
Query: 1715 EVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRS----LKEHFLRE 1548
+ + + ELQ+E D+ I+ + +R E ++ K R L E+ RE
Sbjct: 4272 KNKLEQMKFELQREADE----IRKIKEETQNERQSLEKMTKALIKEREDLVHLAEYTKRE 4327
Query: 1547 EE--DEVLERSASNLA-------IMKAIRE------EELRKEKDGKSALVENGEG---CE 1422
+E DE+ + S++A I++ +RE E++ EK+ KS L E+ E
Sbjct: 4328 KEMLDEMQVANKSSMADLQREKRILEEMRENISKQTEDIENEKE-KSKLREDELKKLQTE 4386
Query: 1421 AEKQ----GLEKTVLERRASNLDTMDAIHEEELRKEKVD-----KSALTENGEGCEAEKQ 1269
+KQ +EKT +E + + EL+K+ D K LTE E E +
Sbjct: 4387 VQKQQSEIDMEKTNIESERAVMIREKQNMMTELKKKSEDVEIQMKEILTEK-ELLENDSN 4445
Query: 1268 GPEKTVLDLEPTIPSL---NDALQRDLDRVMAEKQALEKRCSDLE--AKNASLTDNQEGH 1104
+K + DL+ + S+ +++L+ D + EK+ L++ +DL+ A + H
Sbjct: 4446 LLKKDMEDLKQKLMSIERDSESLKLDREAFGNEKEVLKQMKTDLQIQADEIEKIKLETQH 4505
Query: 1103 EAEIERKLEASNLTHNDELHK---EKDDKKSIMNDLDR--------VKAEKQVLESKVSD 957
+ + + A DE++ E + K ++N++DR ++++K +LE + +
Sbjct: 4506 DRQRVEEKTAQIQKDRDEINNLIVETNRKDMVLNEMDRDIEEKIKSIQSDKDMLEKERHN 4565
Query: 956 LETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDY 777
LE T S L + E ER +E +K+ + + + +++ H E K D+
Sbjct: 4566 LEKTRSELARAKENLETQREI---ERKDIEKMKKNISREMHEIK---HQEEQMKQKQDEL 4619
Query: 776 N-------------EAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLS--------E 660
+ E EK+ + K S+L+ S L DK + + DI + +
Sbjct: 4620 DQLKTEIQNLQQELEKEKEIIMKARSQLDLRQSEL-DKQQTNMNDIMETMKNERKQLDKD 4678
Query: 659 VTELQEDLNKESKEKQDLEKRVLELTSKLE 570
E +E + KEK D ++ L L+
Sbjct: 4679 KEETEEQKQEMEKEKHDFDQSRKSLDEDLK 4708
Score = 73.2 bits (178), Expect = 9e-10
Identities = 101/486 (20%), Positives = 210/486 (43%), Gaps = 13/486 (2%)
Frame = -3
Query: 2036 TLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIK 1857
TL + N + I N+ L + + L D+ L + E + N +++
Sbjct: 7504 TLEEMRANISKQVETITNENKSLSSRESELAKLQEDI------LQQQQEMDELKNTIMME 7557
Query: 1856 KA-LDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQ 1680
LD+R SD+ D Q++ +D M+ ++N+E L + + +
Sbjct: 7558 MCQLDQRQSDI--DLLQKEVDDLMD--------------FTKTEMANVERERLEVLAQTR 7601
Query: 1679 KEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEV-LERSASNLAI 1503
K D +L + A E + +NE +E + L ++ ++D++ ++R NL +
Sbjct: 7602 NIKSDMVSLKMEKEACEQLRLKLNEEKDLIEKERELLTKNLDHTDKDKMDMKRELENLKV 7661
Query: 1502 MKAIREEELRKEKDGKSALVENGEGCE--AEKQGLEKTVLERRASN----LDTMDAIHEE 1341
K + E ++ + K +L G + +EK E+ ++E A+ LD + E
Sbjct: 7662 EKETIKNEKKELEKMKISLQRKAIGFKEFSEKTKDERPIVEEMAAQFTRQLDISERPAEG 7721
Query: 1340 ELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEK 1161
+ +E++D++ + EKT DL+ T +N D + + ++ L K
Sbjct: 7722 KFIEERLDQTEKKRRKTYYTEDLFQEEKT--DLQKTKEEIN----YDREEIYRQRTELNK 7775
Query: 1160 RCSDLEAKNASLTDNQEGHEAEIERKLEASNLTHNDELHKEKDDKKSIMNDLDRVKAEKQ 981
E E +++ SNL + + KEK+ + N+LD+++AE
Sbjct: 7776 -------------------EKETLKQMHTSNLKEIENIEKEKEKIQRTWNELDQIRAE-- 7814
Query: 980 VLESKVSDLETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEM 801
L++K D++ T + + E + D E NE+D L+ ++ ++K + +L+ E
Sbjct: 7815 -LQNKQRDMDDTTNIMMKEKAELARDLENLQNEKDELQKSRENIQKLMKELQ------EE 7867
Query: 800 KTGKDDDYNEAEKQ---TLKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQ--EDL 636
+ + N+ +Q +K + L+E + + + + L+ D I ++ +LQ +D+
Sbjct: 7868 RLKTSEALNKERQQFTEEIKLKNDSLDEIQAEIDRQKRALVTDKEIITKQMMDLQKTQDV 7927
Query: 635 NKESKE 618
++S E
Sbjct: 7928 RRQSDE 7933
Score = 72.8 bits (177), Expect = 1e-09
Identities = 109/496 (21%), Positives = 222/496 (44%), Gaps = 26/496 (5%)
Frame = -3
Query: 1994 CIVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAI-IKKALDKRISDLKAD 1818
C+ D L+ ++A E + L+ KT ELER+ D+ I ++ D++ + A
Sbjct: 5544 CLDRDAESLKLDREAFENEKEVLKQMKT----ELEREADEIEKIKLETQHDRQRVEEMAA 5599
Query: 1817 APQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDKTALIKDLV 1638
Q+D+ D++N LI L + E+++ + DK L K+
Sbjct: 5600 QIQKDR-DEINNLIEETNRKDMV----------LNEKNRDIEEKIKSIQSDKDMLEKEKH 5648
Query: 1637 AAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNLAI-MKAIR--EEELRKE 1467
E + + ++ LE + + +E ED LE+ N+ M I+ EE++ ++
Sbjct: 5649 DLEKTRSELYKVKEDLEKQKENTLAEIQKERED--LEKMNENITREMHEIKHQEEQMNQK 5706
Query: 1466 KDG----KSALVENGEGCEAEKQGL--EKTVLERRASNLDTMDAIHEEELRKEKVDKSAL 1305
+D K+ + + E EK+ + +++ L+ R S LD + + K ++ L
Sbjct: 5707 QDELDQLKTEIQNLQQELEKEKEIIMKDRSQLDLRQSELDKQQTNMNDIMETMKNERKQL 5766
Query: 1304 TENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASL 1125
++ E E +KQ EK +++ + SL++ D ++ +KQ E+ + LE L
Sbjct: 5767 DKDKEEMEEQKQEMEKERDNMDQSRKSLDE----DQKKMKLQKQMFEEEKNKLEQMKIEL 5822
Query: 1124 TDNQEGHEAEIERKLEASNLTHNDELHKEKDD----KKSIMNDLDRVKAEKQVL------ 975
EA+ K++ L K ++ K+S+ + + K EK++L
Sbjct: 5823 E-----READEISKIKEETQNKRQRLEKMTEELIREKESLAHLAEDTKTEKKILDEMKVA 5877
Query: 974 -ESKVSDLETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMK 798
ES ++DL+ S L ++M +N + L E E K L E + ++ +
Sbjct: 5878 NESSMADLQREKSIL-----EEMRENISKLKEYIDNEKEKSKLR------EDELKKLQTE 5926
Query: 797 TGKDDDYNEAEKQTLK-KRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESK 621
K + EK ++ +R + + E +++T+ KK +D+ I + E+ +E L+ + K
Sbjct: 5927 VQKQQSKIDMEKTNIESERAAMIREKQNMMTE-LKKKSEDVEIQMKEILTEKELLHNDRK 5985
Query: 620 ----EKQDLEKRVLEL 585
+ ++L++++++L
Sbjct: 5986 LLTRDVENLQQKLIDL 6001
Score = 72.4 bits (176), Expect = 2e-09
Identities = 119/603 (19%), Positives = 247/603 (40%), Gaps = 64/603 (10%)
Frame = -3
Query: 2042 IATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAI 1863
+ L E+ ++ K ++++ I ++ Q L + + L E+E K D
Sbjct: 9072 VRNLKGEMERRMEESKVEIDEKEIFKSEIQRLIQDIGQIRENLGGLKTEIENTKRD---- 9127
Query: 1862 IKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEEL 1683
K L+K ++L + Q+++E L + ++E++ ++ E+
Sbjct: 9128 -KSNLEKMKAEL--EEKQQEEESMREILQKEKEELEQLKKDINREKEDIEISRELVESEI 9184
Query: 1682 -----------QKEKDDKTALIKDLVAAEPGKRTVNEIVSHLES----------KSRSLK 1566
QK K++ + ++L+ + +N V HL K ++
Sbjct: 9185 YEGEVKGFTDVQKYKEELQIVTEELLTKKRNLEQLNSDVQHLMQTLEEVDIQYIKKKAEL 9244
Query: 1565 EHFLRE--EEDEVLERSASNL--------------AIMKAIREEELRKEKDGKSALVENG 1434
EH E + +++LE+ L +++I E L+K +D + +
Sbjct: 9245 EHITSEIQKREQILEKQKKKLEENGWIIEEIEMMKVTLESINMEILQKRED----MEKEK 9300
Query: 1433 EGCEAEKQGLE--KTVLERRASNLDT--MDAIHEEELRKEKVDKSALTENGEGCEAEKQG 1266
E EKQ E + L+R+ +++ I E++ K K+D E E E +
Sbjct: 9301 ENLRREKQETELFRGELQRQRDEVESSRQALIMEKDQFKLKIDHQR-NEMSAAFEKEHKR 9359
Query: 1265 PEKTVLDLE----PTIPSLNDA------LQRDLDRVMAEKQALEKRCSDLEAKNASLTDN 1116
E DLE SLNDA LQ+ + + EK+ +E+ ++ + +
Sbjct: 9360 LENMENDLENQRAKLAESLNDAAKMEQKLQQMKNELNKEKEQVEEMKQMVKTERVKIEQE 9419
Query: 1115 QE-----------GHEAEIERKLEASNLTHNDELHKEKDDKKSIMNDLD-RVKAEKQVLE 972
+E GHE ++++K E + D+L ++ + + + DL +++ ++Q +E
Sbjct: 9420 KEEMRKQTQEIEDGHE-KLQKKTEIA-----DKLLQDANSESDRLKDLSMKLQMQRQDIE 9473
Query: 971 SKVSDLETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTG 792
+++ET +L+ ++ DD N+RD E LE + +L D+E K
Sbjct: 9474 KTNTEMETKKRSLDRMSRELQDDKIRLKNDRDAYEKDMTHLELKREELVRETEDLERKIL 9533
Query: 791 KDDDYNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQ 612
+ + +E K+ ++ + LE + K + K++ SE +L ++
Sbjct: 9534 QQREQDEMAKRDIENQTEALEVMKVDILKKRNEFAKEMENVHSERQKLLLLQGALQSQES 9593
Query: 611 DLEKRV-LELTSKLEKCICGARDGLSTIKEAWMSDCMVPDNWVPFEDLVQGFSRKTSPLD 435
+LE RV +E L++ + + E MS+ + + + L++ R+ L+
Sbjct: 9594 ELENRVFMEEQKHLKQAKAETEECRKQLAE--MSETVTTEQ-NEYRKLIEELQREKEQLE 9650
Query: 434 ITK 426
I+K
Sbjct: 9651 ISK 9653
Score = 71.6 bits (174), Expect = 3e-09
Identities = 103/494 (20%), Positives = 209/494 (42%), Gaps = 8/494 (1%)
Frame = -3
Query: 2042 IATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLND---ELERKKDDN 1872
I ++ +E +K+D + I N+ KQ L+ K LE + +N + +++ D+
Sbjct: 10590 IKSIIEETSRQKEDLEKISTGMNV---QKQELKNKKDTLEQEREEINHKWTQFQQRIDEF 10646
Query: 1871 NAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILH 1692
+A ++K ++ +++ K +R +++N I ++ + H
Sbjct: 10647 DAQVRKQKEEDLTNQKKMEEERKCLEEVNGKII-----------------EMKTKAELEH 10689
Query: 1691 EELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASN 1512
E+ ++ I++L +T+ E + + K+ ++ E ED L++ S
Sbjct: 10690 HEINQK-------IEEL-------QTLQEQIMKEKEKAEAMTIKLKMERED--LDQIKSE 10733
Query: 1511 LAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGL--EKTVLERRASNLDTMDAIHEEE 1338
L K + E +K D + + E E K + +K +E+ S LD + I + +
Sbjct: 10734 LVREKTEVDHEQKKLNDDIKMIEQEKEDLEKMKSEIMTQKQEMEKERSELD--NKIQQTD 10791
Query: 1337 LRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKR 1158
L K ++KS E E+Q E I + L + ++ E+ L +
Sbjct: 10792 LEKHDIEKSKEIVEKLMFEVEEQRHE---------IQLQKEELDIERQKIADEQDLLIQN 10842
Query: 1157 CSDLEAKNASLTDNQE--GHEAEIERKLEASNLTHNDELHKEKDDKKSIMNDLDRVKAEK 984
S+L+ +N + + E E E +++EA L KEK++ KSI + R +K
Sbjct: 10843 KSELQNENERIRNINEVIKKERETLKEMEA-------HLEKEKEEMKSITEETRR---QK 10892
Query: 983 QVLESKVSDLETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIE 804
+ LE +D++ + N+ + +RD LE K+ + L+ I + +
Sbjct: 10893 EDLEKMSTDIK--------------EQNQDLMKQRDLLEQEKEDINHEWTQLQQRIDEFD 10938
Query: 803 MKTGKDDDYNEAEKQTLKKRISELEEA-ISILTDKAKKLLKDINIWLSEVTELQEDLNKE 627
+ K + + +++ +K+ LEE I+ K K L+DI + E +E K
Sbjct: 10939 AQVSKQKEEDLTKQKEMKEERKSLEETKARIIEMKTKAELEDIKKEKEKEEEEEEMRVKV 10998
Query: 626 SKEKQDLEKRVLEL 585
+ ++L++ EL
Sbjct: 10999 EMDGKELDRIKSEL 11012
Score = 71.6 bits (174), Expect = 3e-09
Identities = 112/532 (21%), Positives = 220/532 (41%), Gaps = 62/532 (11%)
Frame = -3
Query: 1982 DRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKAL--------DKRISDL 1827
D+ ++ K +LE ADL+ L++E+ + + I + A ++ + +
Sbjct: 13991 DKLSIQREKDSLEEIKADLQRKAEKLDEEMRKAVQITSQISQDAKILDDDREKEEELRSM 14050
Query: 1826 KADAPQRDQ--EDDMNALIXXXXXXXXXXXXXXKIVSNLEV----NILILHEELQKEKDD 1665
+AD ++ + E D+ L + +LE N L L +EL+KEK
Sbjct: 14051 RADIERQAKILESDVQLLQTEKEILEKSKTENDLLREDLEKQRKRNDLTL-QELRKEKMA 14109
Query: 1664 KTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVLE--RSASNLAIMKAI 1491
+I D+ + + V+ L+++ SLK+H L+ +E E+ E + +L + +
Sbjct: 14110 LEQMITDITKEK-------DAVASLQNEV-SLKQHELKNKETELDEQRKEMDDLRMQLEM 14161
Query: 1490 REEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTM---------------D 1356
R+ K++ + + + ++ + E R D + D
Sbjct: 14162 RQNSTNKQQQEVDVFIVENMKMRNDLESMKTLLDEERRQLQDNIKTFEDQKNVLHPSKTD 14221
Query: 1355 AIHE-EELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLN---DALQRDLDRV 1188
A+ + +EL K D E+ E E K ++ + + SLN + ++++
Sbjct: 14222 AVQQTDELEKFTTDIKTEKEHVEKEREEIDVLNKEIIKSKEELQSLNLEIEMFKQEIAGK 14281
Query: 1187 MAEKQALEKRCSDLEA------------KNASLTDNQEGHEAEIERKL-----EASNLTH 1059
A+ ++LE+ +DL A K ++ D ++ E E++ L E L +
Sbjct: 14282 RAQIESLEQLRADLLAGADDIKTLVQTEKQMAIEDTEKKTEVELQMNLQKQKNELEELRN 14341
Query: 1058 NDELHKEKDDKKSIMNDLDR---------VKAEKQVLESKVSDLETTYSTLNNELQQKMD 906
E K + + + IM D + +K+E+ VLE + S+L LN ++Q++ +
Sbjct: 14342 TIEAEKHQVENRKIMLDKQQKEVEDIMTVIKSERDVLEKEKSELNKLSHVLNEKVQREQE 14401
Query: 905 DNEAFLN-ERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELE 729
+ E L ERD +E K+ +E +EKQ++++ +EL
Sbjct: 14402 ELERLLEKERDDIENCKKIIE-------------------------SEKQSIERERAEL- 14435
Query: 728 EAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLELTSKL 573
K+L +++ + E T LQ+D N KEK+ LE T ++
Sbjct: 14436 ----------KRLKEEVEVQ-HERTLLQQDKNMIQKEKEHLEGEKARTTEEI 14476
Score = 70.1 bits (170), Expect = 7e-09
Identities = 113/520 (21%), Positives = 220/520 (42%), Gaps = 45/520 (8%)
Frame = -3
Query: 2018 LNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKA---L 1848
L EK+ + + D L ++ L+ A + K + E +KD+ AI++K +
Sbjct: 13167 LQEKNVQMGTILDE--LNKRQEELDAIKAKTQREKEQMGHTEELEKDELIAILQKREEIV 13224
Query: 1847 DKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILI-LHEELQKEK 1671
+ + +++ + +E D + +++ N E + L + L+K+K
Sbjct: 13225 KRHMEEIQNQREELQKEKDQFGNMQAELQKGQLEMEMHQLMLNSERDELNGMRVNLEKQK 13284
Query: 1670 DDKTALIKDLVAAEPG---------KRTVNEIVSHLESKSRSLK----EHFLREEEDEVL 1530
++ + ++L + P K+ V E+ + L + + E R E+ + +
Sbjct: 13285 EEFELMQQNLESRRPESLLEDILKEKKRVEEMAAQLSKEQEEFRNIMSETIKRMEKIKQI 13344
Query: 1529 ERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAI 1350
E I A EE +KE D + + E CE ++ + + L + + +D
Sbjct: 13345 EGEIKTKQIEMACLEELKQKELDEQKNMRE----CENQELQMRREELAKMKTEID----- 13395
Query: 1349 HEEELRKEKVDKSALTENGEGCEAE-------KQGPEKTVLDLEPTIPSLNDALQRDLDR 1191
+ ++++ K E CE E K+ PEK +++ +D + +D
Sbjct: 13396 ----IERDEIQKLRKQYEKEKCELEQIKPDLQKREPEKIDAEVQ------HDEIHGGIDS 13445
Query: 1190 VMAEKQALEKRCSDLEAKNASLT----------DNQEGHEAEIERKLEASNLTHNDELHK 1041
+ E++ +EK +DL+ K D E EAEIE+ A ND
Sbjct: 13446 LKEEREEIEKMKADLQNKLREAENMRDIMKREKDELEKKEAEIEQM--AVETEDNDSDKN 13503
Query: 1040 EKDDKKSIMNDLDRVKAEKQVLES-------KVSDLETTYSTLNNE---LQQKMDDNEAF 891
+D+ I L K +K LE + ++LET L E L +K+ + E F
Sbjct: 13504 LQDEMMKIEAILKVTKKQKNYLEQMNENLTREKTELETNCQMLEREKTELNKKVKETEEF 13563
Query: 890 -LNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISI 714
+++ + EA ++ +E RV+D A H+ ++K +++ N E+ +KK+ LEE+++
Sbjct: 13564 HMSKMEEREAERKTIE-RVMDEMAEEHE-KIKKEREELVNMEEE--IKKQRRVLEESMNE 13619
Query: 713 LTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRV 594
+T K +ELQ + ++ K+KQ LE +
Sbjct: 13620 MTKKK--------------SELQHERSELYKQKQQLEDMI 13645
Score = 69.3 bits (168), Expect = 1e-08
Identities = 108/561 (19%), Positives = 243/561 (43%), Gaps = 50/561 (8%)
Frame = -3
Query: 2051 EAAIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDE---LERKK 1881
E+ L++E +D+ K + +N+L +K + +LE T + E +E+++
Sbjct: 14188 ESMKTLLDEERRQLQDNIKTFEDQKNVLHPSKTDAVQQTDELEKFTTDIKTEKEHVEKER 14247
Query: 1880 DD----NNAIIK-----KALDKRISDLKAD-APQRDQEDDMNALIXXXXXXXXXXXXXXK 1731
++ N IIK ++L+ I K + A +R Q + + L +
Sbjct: 14248 EEIDVLNKEIIKSKEELQSLNLEIEMFKQEIAGKRAQIESLEQLRADLLAGADDIKTLVQ 14307
Query: 1730 IVSNLEVNI------LILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSL 1569
+ + + L LQK+K++ L ++ + AE K V L+ + + +
Sbjct: 14308 TEKQMAIEDTEKKTEVELQMNLQKQKNELEEL-RNTIEAE--KHQVENRKIMLDKQQKEV 14364
Query: 1568 KEHF-LREEEDEVLERSASNLAIMKAIREEELRKEKDGKSALVENG----EGC----EAE 1416
++ + + E +VLE+ S L + + E++++E++ L+E E C E+E
Sbjct: 14365 EDIMTVIKSERDVLEKEKSELNKLSHVLNEKVQREQEELERLLEKERDDIENCKKIIESE 14424
Query: 1415 KQGLEKTVLERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEP 1236
KQ +E+ E + + ++ HE L ++ DK+ + + E E EK + + +L+
Sbjct: 14425 KQSIERERAELKRLK-EEVEVQHERTLLQQ--DKNMIQKEKEHLEGEKARTTEEIHNLKE 14481
Query: 1235 TIPSLNDALQRDLDRVMAEKQALE--------------KRCSDL---EAKNASLTDNQEG 1107
I + L + A++Q E K+ D+ E TD +
Sbjct: 14482 EIKRKSSELDMLNKEIEAKRQEEELHGLPEEIEIEDHLKKEDDVLREEIIKKQQTDASQK 14541
Query: 1106 HEAEIERKLEASNLTHNDELHKEKDDKKSIMNDLDRVKAEKQVL----ESKVSDLETTYS 939
+ + + +A T DE+ K + ++ + + A++ ++ ++ S+++
Sbjct: 14542 FQLKTTSR-DAETQTSLDEITKTDERRQRALEETVATTAKQPIVIKLEDTLTSEVQEMRD 14600
Query: 938 TLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQ 759
LNNE+++ E+D L+ K ++ ++ + E + + + +++ +
Sbjct: 14601 HLNNEIKELARMKTIMKMEKDQLKQAKSDIQTQMEEFERNMEEAMEEKSRNE-------E 14653
Query: 758 TLKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLELTS 579
L + + E+ + L K K++ + +L ++ +L+ + K+K+++E +L+L
Sbjct: 14654 KLLQLTHDKEDLSNTLDKKNKEIENNTETFLKKIAQLETTIVLMKKDKENIENELLQLKQ 14713
Query: 578 -KLEKCICGARDGLSTIKEAW 519
+ E+ I D ST KE +
Sbjct: 14714 IEQEREIQRKADVTSTEKEMY 14734
Score = 68.9 bits (167), Expect = 2e-08
Identities = 118/565 (20%), Positives = 246/565 (43%), Gaps = 87/565 (15%)
Frame = -3
Query: 2000 KKC-IVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKALD-----KR 1839
+KC I N + I++ +E + +++ K L+ E ++ D+ + +I+ + +R
Sbjct: 11071 EKCDIENSKEIVQKLMVEVEEQKHEIQFQKEELDIERQKIADEQDLLIQNKSELQNENER 11130
Query: 1838 ISDL-KADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDK 1662
I +L + +R+ +M A + + ++ L E+L+K D
Sbjct: 11131 IRNLNEIIKKERETLKEMEAHLEKKKEE----------IKSVSEETRRLKEDLEKMSTDV 11180
Query: 1661 TALIKDLVAAEPGKRTVNEIVSHL----------------ESKSRSLKEHFLREEEDEVL 1530
KDL+ E ++H + K + L + +E+ + L
Sbjct: 11181 NKQNKDLMNQRDLLEQEREEINHKWKQLQQRIDEFDAQVSKQKEQDLPKEKGMKEDRKSL 11240
Query: 1529 ERSASNLAIMKAIRE-EELRKEKDGKSALVENGEG-----CEAEKQGLE--KTVLERRAS 1374
E + +N+ MK E EE++KEK+ ++ E E E E++ L K+ LER S
Sbjct: 11241 EETKANVIEMKTKAEPEEIKKEKEKENEEEEEEEEEIRVIVETERKELYQIKSELERVRS 11300
Query: 1373 NLDT--------MDAIHEEELRKEKV-------------DKSALTENGEGCEAEKQGPEK 1257
+D M I +E+ EK+ ++S L + EK EK
Sbjct: 11301 EIDHEQKKLNDYMKMIEQEKEDLEKMKSEIMKQRQQMEEERSELDNKIQQTNLEKHDIEK 11360
Query: 1256 TVLDLEPTIPSLNDA---LQRDLDRVMAEKQALEKRCSDLEAKNASL-TDNQEGHEAEIE 1089
+ +E + + + +Q + + E+Q + + L A L +N+ + + E
Sbjct: 11361 SKEIVEKLMVEVEEQRKDIQLQKEELDIERQKIADEQNLLVQNKAKLQNENERIKKVDEE 11420
Query: 1088 RKLEASNLTHND-ELHKEKDDKKSIMNDLDRVKAEKQVLESKVSD-----------LETT 945
K E L + L KEK++ +SI+ + R K + + + + +++ LE
Sbjct: 11421 IKKERETLREMEIHLKKEKEELRSIIEETQRRKEDLEKMSTDINEQKLHLKNQRDLLEQE 11480
Query: 944 YSTLNNE---LQQKMDDNEAFLNE------RDGLEAVKQGLEK---RVLDLE--ATIHDI 807
+N+E LQQ++D+ +A +++ + +E ++ LE+ R+++++ A + +I
Sbjct: 11481 REEINHEMTQLQQRIDEFDAQVSKQREDLTKQEMEEERKSLEETKARIIEMKTKAELQEI 11540
Query: 806 EMKTGKDDDYN-----EAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQE 642
+ ++D+ E E++ L + SEL+ S + + KKL D I E +L++
Sbjct: 11541 MQEKEEEDEEEMRVIVEMEREELNQIKSELKRVRSEIDHEQKKLNDDKKIIEQEKEDLEK 11600
Query: 641 DLNKESKEKQDLEKRVLELTSKLEK 567
++ ++Q +E+ EL +K+++
Sbjct: 11601 MKSEIMTQRQQMEEERSELDNKIKQ 11625
Score = 68.2 bits (165), Expect = 3e-08
Identities = 116/566 (20%), Positives = 230/566 (40%), Gaps = 63/566 (11%)
Frame = -3
Query: 2075 LESKVSVFEAAIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDE 1896
+E ++ + +A L + E D++K N+ E Q L+ + +L KT + +
Sbjct: 13344 IEGEIKTKQIEMACLEELKQKELDEQK------NMRECENQELQMRREELAKMKTEI--D 13395
Query: 1895 LERKKDDNNAIIKKALDKRISDLKADAP--QRDQEDDMNALIXXXXXXXXXXXXXXKIVS 1722
+ER D ++K +K +L+ P Q+ + + ++A +
Sbjct: 13396 IER---DEIQKLRKQYEKEKCELEQIKPDLQKREPEKIDAEVQH---------------D 13437
Query: 1721 NLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEE 1542
+ I L EE ++ + K L L AE + + LE K +++ + E+
Sbjct: 13438 EIHGGIDSLKEEREEIEKMKADLQNKLREAENMRDIMKREKDELEKKEAEIEQMAVETED 13497
Query: 1541 DEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKT--VLERRASNL 1368
++ + + ++AI L+ K K+ L + E EK LE +LER + L
Sbjct: 13498 NDSDKNLQDEMMKIEAI----LKVTKKQKNYLEQMNENLTREKTELETNCQMLEREKTEL 13553
Query: 1367 DT---------MDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLND 1215
+ M + E E ++ +++ + E E E K+ E+ V ++E I
Sbjct: 13554 NKKVKETEEFHMSKMEEREAERKTIER-VMDEMAEEHEKIKKEREELV-NMEEEIKKQRR 13611
Query: 1214 ALQRDLDRVMAEKQALEKRCSDLEAKNASLTD---------------NQEGHEAEIERKL 1080
L+ ++ + +K L+ S+L + L D Q+ + +I ++
Sbjct: 13612 VLEESMNEMTKKKSELQHERSELYKQKQQLEDMIASESKRDVDTERSRQDKEDEQILKRE 13671
Query: 1079 EASNLTHNDELHKEKDDKKSIMNDLDRVKAEKQVLESKVSD--------------LETTY 942
D+L KEK+D ++ ++R K + ++S+++D ++T
Sbjct: 13672 REEIADMKDQLLKEKEDVETTKERINREKEHIEKMQSQLNDQKEEMDLENQKLLYMKTEI 13731
Query: 941 STLNNELQQKMDDNEAFLNERDGLEAV-----KQGLEKRVL-------------DLEATI 816
N L++ M D + ER+ + A+ K+ ++ +L +++
Sbjct: 13732 QVKTNALEKMMQDLQ---KERENVNALVIQHQKEREQRDILIEENKRKEKHAEAEIQRQF 13788
Query: 815 HDIE-MKTGKDDDYNEAEKQT--LKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQ 645
DIE +K + N+ +K LK R ELE I KK K+ ++ E+Q
Sbjct: 13789 EDIESVKVRLVTESNQIDKMNSELKTRSEELENLI-------KKQQKEFE---TKENEMQ 13838
Query: 644 EDLNKESKEKQDLEKRVLELTSKLEK 567
+ K +LE++ EL +K+EK
Sbjct: 13839 RERKALEKMNAELERKSTELKNKIEK 13864
Score = 67.8 bits (164), Expect = 4e-08
Identities = 122/593 (20%), Positives = 248/593 (41%), Gaps = 81/593 (13%)
Frame = -3
Query: 2027 DELLNEKD-DKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIK-- 1857
D + + D ++ I N + I++ +E + D+ K L+ E ++ D+ +++
Sbjct: 11620 DNKIKQTDLERHDIENSKEIVQKLMVKVEEQRKDIRLQKEELDIERQKIADEQGLVVQNK 11679
Query: 1856 ----------KALDKRISDLKA-----DAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVS 1722
K +D+ I K +A R ++++M ++I
Sbjct: 11680 AKLQNENERIKEMDEEIKKEKETLKEMEAHLRKEKEEMRSVIEETQRRKKEDLEKMSTDV 11739
Query: 1721 NLEVNILILHEELQKEKDDK-----TALIKDLVAAEPGKRTVNEIVSHL-ESKSRSLKEH 1560
N + L+ +L K++ ++ T L ++ ++E + + + K L +
Sbjct: 11740 NKQNQDLMNQRDLLKQEREEINHKWTQL----------QQRIDEFDAQVSKQKEEDLTKQ 11789
Query: 1559 FLREEEDEVLERSASNLAIMKAIRE-EELRKEKDGKSALVENGEGCEAEKQGLE--KTVL 1389
EEE + LE + + MK E E+++KEK+ + V + E +K+ L+ K+ L
Sbjct: 11790 KKMEEERKSLEETKIKIIEMKTKTEPEKIKKEKEKEEEEVMRAK-VEMKKEELDQIKSQL 11848
Query: 1388 ERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDAL 1209
ER S +D HE+ +K DK + + E E K K +E L++ +
Sbjct: 11849 ERVRSEID-----HEQ--KKLNDDKKMIEQEKEDLEKMKSEIMKQRQQMEEERSELDNKI 11901
Query: 1208 -QRDLDR--VMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIER---------------K 1083
Q DL+R + K+ ++K ++E + + +E E +IER K
Sbjct: 11902 KQTDLERHDIENSKEIVQKLMVEVEEQRKDIRLQKE--ELDIERQKIADEQGLVVQNKAK 11959
Query: 1082 LEASN---LTHNDELHKEKDDKKSIMNDLDRVKAE-KQVLES----KVSDLETTYSTLNN 927
L+ N ++E+ KEK+ K + L + K E + V+E + DLE + +N
Sbjct: 11960 LQNENERIKEMDEEIKKEKETLKEMEAHLRKEKEEMRSVIEETQRRQKEDLEKMSTDVNK 12019
Query: 926 ELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATI-----HDIEMKTGKDDDYNEAEK 762
+ Q M+ + ER+ + L++R+ + +A + D+ + +++ E+
Sbjct: 12020 QNQDLMNQRDLLKQEREEINHKWTQLQQRIDEFDAQVSKQKEEDLTKQKKMEEERKSLEE 12079
Query: 761 QTL---------------KKRISELEEAISILTDKAKKLLKDINIWL----SEVTELQED 639
+ K++ E EE + + K+ L I L SE+ Q+
Sbjct: 12080 TKIKIIEMKTKTEPEKIKKEKEKEEEEVMRAKVEMKKEELDQIKSQLERVRSEIDHEQKK 12139
Query: 638 LNKESK----EKQDLEKRVLELTSKLEKCICGARDGLSTIKEAWMSDCMVPDN 492
LN + K EK+DLEK E+ + ++ + + I++ ++ C + ++
Sbjct: 12140 LNDDKKMIEQEKEDLEKMKSEIMKQRQQMEEERSELENKIRQTYIEKCDIENS 12192
Score = 67.4 bits (163), Expect = 5e-08
Identities = 92/447 (20%), Positives = 194/447 (43%), Gaps = 36/447 (8%)
Frame = -3
Query: 1622 KRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNLAIMKAIREEELRKEKDG-KSAL 1446
+ T E++ LE + R+ K R L + +++K KD K
Sbjct: 80 RMTEPELIQELEWRQRNTKHTQTETGSPPSSPREKRRLEDKSGL-SSDIQKRKDSLKRRR 138
Query: 1445 VENGEGCEAEKQGLEKTVLERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQG 1266
E E ++ E T ER + +D M ++++++++ + + +T EK
Sbjct: 139 FETMRAIEQIEKLWEGTKQER--TEIDNM----KQKIQRQQDEITRMT-------TEKGQ 185
Query: 1265 PEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIER 1086
E+T+ ++ I + + + R+ + V E++ +E+ SDL+A+ +SL Q+ E ER
Sbjct: 186 LERTITHMKAEIDHIRERMDRNKEEVNRERERVEQMRSDLQAEQSSL--QQKRDEIMTER 243
Query: 1085 K----LEASNLTHNDELHKEKDDKKSIMNDLDRVKAEKQV----LESKVSDLETTYSTL- 933
+ + L +EL ++ K M ++++K+ QV +E K+ + + +
Sbjct: 244 QNLEMIRYETLRQQEELESNRESTKHEMERMEQMKSAIQVQINEIEMKIGETQKAKDLME 303
Query: 932 ---------NNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDD 780
NEL++K +D +RD E +K L++ +++E H+ E + +
Sbjct: 304 QMKAEIEDEKNELEKKKED---IKRQRDQFEQIKLDLQQVKMEMEQRWHETEKEGLEQRA 360
Query: 779 YNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEV--TELQEDLNKESK----- 621
+ EK+ LK E++ + ++ ++ K + +S++ L+E+ E+K
Sbjct: 361 VIQREKEQLKYLQDEIQR-VREEVERNREFSKQEHARISQLRAQALEENNLIENKWHDIL 419
Query: 620 -EKQDLEKRVLELTSKLEKCICGARDGLSTIKEAW----MSDCMVPDNWVPFEDLVQGFS 456
+++DLE+ E+ E+ + +K+ W + + + + E V
Sbjct: 420 RKEKDLEEMKHEIERGREELVMNG----ELVKKEWEKIEQAKVDIQSHMISMEGRVDEIK 475
Query: 455 RKTSPLDITKT-----CDAVDISEDST 390
R+T L KT DA++ +D T
Sbjct: 476 RETERLKHIKTEMQRDKDALEKQKDDT 502
Score = 65.1 bits (157), Expect = 2e-07
Identities = 117/597 (19%), Positives = 242/597 (40%), Gaps = 108/597 (18%)
Frame = -3
Query: 2033 LNDELLNEKDDKKCIVN--------DRNILEAAKQALEYKVADLEAAKTTLNDELERKKD 1878
LN+ LN+ K ++ ++ +E K ++ + DL+ +T LN + + +D
Sbjct: 1889 LNELTLNQIKTKSDVLEKISELNSQQKDEIENEKSKIKIREYDLQQMQTDLNRQQKEMQD 1948
Query: 1877 DNNAII--KKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLE-VN 1707
NA+ K L K ++ A Q Q DM NL+
Sbjct: 1949 IQNAVFMEKSELKKSQDEI---AEQLKQVGDMMQFTQNEK-------------DNLDRER 1992
Query: 1706 ILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEV-L 1530
I+ ++LQ E+D L ++L + + K+ V LE SL E+ ++ L
Sbjct: 1993 AAIIEQKLQMERDMTHLLNRELESLKLVKKEVLNEKRLLEDCRISLMRDMQDLEQMKINL 2052
Query: 1529 ERSASNLAIMKAIREEELRKEKDGKSALVENGEGCE----AEKQGLEKTVLERRASNLDT 1362
ER + + + EE K + L E+ E AEKQ LE +E + +
Sbjct: 2053 EREKEEMQLQRQSIAEEKDKLESVLQTLAEDTEKLRIDTLAEKQKLEDAAVELQKERDEI 2112
Query: 1361 MDAIHEEELRKEKVDK----------------------SALTENGEGC------------ 1284
M+ E + ++E VDK +A+ EN
Sbjct: 2113 MNIAEETKRKREDVDKIRVGIEKQEITFKDLKADLQKEAAIVENQRQAVQKDIQNVKDME 2172
Query: 1283 ---EAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQ 1113
+ E+Q ++ V ++E +L D +Q ++D+ E+Q +E + +LE + + L +++
Sbjct: 2173 VQIQKERQYMDRLVEEIEKRTKAL-DEMQMEVDK---ERQEVESKRDELEQETSKLREDE 2228
Query: 1112 EGH----------EAEIERK-----LEASNLT----------------HNDELHKEK--D 1032
+ +AEI+++ L++ N++ N+ +K+K D
Sbjct: 2229 DEFSRQKEKNNIIQAEIQKESDNLELQSENISKERTIFELEKEHLGLRENEAEYKQKQID 2288
Query: 1031 DKKSIMN----DLDRVKAEKQVLESKVSDLETTYSTLNNELQQKMDDNEAFLNERDGLEA 864
+ ++ + +++++A+K K ++T L+++ + E+ E + +E
Sbjct: 2289 ELQNKLRMEKVQVEQMQADKDQQRKKAEYVKTARGRETTALEEQRQEMESLREEYENVEK 2348
Query: 863 VKQGLEKRVLDLEATIHDIEMKTGKDDDYNEA----------EKQTLKKRISELEEAISI 714
K+ + ++ E+ + +EM+ Y E ++Q +K I ++ + I
Sbjct: 2349 QKKHVNEQKELFESRMKSLEMENEAMKKYKEKLDKEYEDLQFQRQLFEKEIQQMRTELQI 2408
Query: 713 LTDKAKKLLKDINIWLSEV------TELQEDLNKESK--EKQDLEKRVLELTSKLEK 567
+ ++ K++ I V E Q+ + ++SK E ++ K++ S++EK
Sbjct: 2409 EAENIERKKKELEIQKPAVYTETYMLETQKPVVEKSKTDELDEVRKKINADLSEVEK 2465
Score = 65.1 bits (157), Expect = 2e-07
Identities = 108/563 (19%), Positives = 242/563 (42%), Gaps = 74/563 (13%)
Frame = -3
Query: 2033 LNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIK- 1857
L++++ +K I + I+E +E + D++ K L+ E ++ D+ N +++
Sbjct: 11344 LDNKIQQTNLEKHDIEKSKEIVEKLMVEVEEQRKDIQLQKEELDIERQKIADEQNLLVQN 11403
Query: 1856 -----------KALDKRISDLKADAPQRD-----QEDDMNALIXXXXXXXXXXXXXXKIV 1725
K +D+ I + + + +++++ ++I +
Sbjct: 11404 KAKLQNENERIKKVDEEIKKERETLREMEIHLKKEKEELRSIIEETQRRKEDLEKMSTDI 11463
Query: 1724 SNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREE 1545
+ ++++ + L++E+++ + L ++ ++E + + + L + + EE
Sbjct: 11464 NEQKLHLKNQRDLLEQEREEINHEMTQL------QQRIDEFDAQVSKQREDLTKQEM-EE 11516
Query: 1544 EDEVLERSASNLAIMKAIRE-EELRKEKDGKS-----ALVENGEGCEAEKQGLEKTVLER 1383
E + LE + + + MK E +E+ +EK+ + +VE E E+ K+ L+R
Sbjct: 11517 ERKSLEETKARIIEMKTKAELQEIMQEKEEEDEEEMRVIVE----MEREELNQIKSELKR 11572
Query: 1382 RASNLDTMDAIHEEE--------LRKEKVD----KSALTENGEGCEAEKQGPEKTV--LD 1245
S +D HE++ + +EK D KS + + E E+ + + D
Sbjct: 11573 VRSEID-----HEQKKLNDDKKIIEQEKEDLEKMKSEIMTQRQQMEEERSELDNKIKQTD 11627
Query: 1244 LEP-TIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASN 1068
LE I + + +Q+ + +V +++ + + +L+ + + D Q G + + KL+ N
Sbjct: 11628 LERHDIENSKEIVQKLMVKVEEQRKDIRLQKEELDIERQKIADEQ-GLVVQNKAKLQNEN 11686
Query: 1067 ---LTHNDELHKEKDDKKSIMNDLDRVKAE-KQVLES----KVSDLETTYSTLNNELQQK 912
++E+ KEK+ K + L + K E + V+E K DLE + +N + Q
Sbjct: 11687 ERIKEMDEEIKKEKETLKEMEAHLRKEKEEMRSVIEETQRRKKEDLEKMSTDVNKQNQDL 11746
Query: 911 MDDNEAFLNERDGLEAVKQGLEKRVLDLEATI-----HDIEMKTGKDDDYNEAEKQTL-- 753
M+ + ER+ + L++R+ + +A + D+ + +++ E+ +
Sbjct: 11747 MNQRDLLKQEREEINHKWTQLQQRIDEFDAQVSKQKEEDLTKQKKMEEERKSLEETKIKI 11806
Query: 752 -------------KKRISELEEAISILTDKAKKLLKDINIWL----SEVTELQEDLNKES 624
K++ E EE + + K+ L I L SE+ Q+ LN +
Sbjct: 11807 IEMKTKTEPEKIKKEKEKEEEEVMRAKVEMKKEELDQIKSQLERVRSEIDHEQKKLNDDK 11866
Query: 623 K----EKQDLEKRVLELTSKLEK 567
K EK+DLEK E+ + ++
Sbjct: 11867 KMIEQEKEDLEKMKSEIMKQRQQ 11889
Score = 62.8 bits (151), Expect = 1e-06
Identities = 107/536 (19%), Positives = 227/536 (42%), Gaps = 55/536 (10%)
Frame = -3
Query: 2027 DELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKAL 1848
+ L KD+ + +R+ LE K ++E NDE++++K + K L
Sbjct: 8374 ETLRGMKDEVQAARKERSELENMKLEFLTMKKNMEKTYEQQNDEIQKEKQQIESS-KMLL 8432
Query: 1847 DKRISDLKADAPQRDQED-----DMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEEL 1683
+ +DL+ + +++ D L+ KI+ NLE L EE
Sbjct: 8433 SRERNDLEQNRADLERQKQIMALDKQKLLAENELLEREKADVIKIIENLES----LREEA 8488
Query: 1682 QKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVLE--RSASNL 1509
+E+ +TA + +R E++ +E+ S E F +++++E R L
Sbjct: 8489 TRERATETA--------QATRRDSEELMQKMEALSM---EDFQEASKNQMVELKRQIDKL 8537
Query: 1508 AIMKAI---REEELRKEKDG-----------KSALVENGEGCEAEKQGLEKTVLERRASN 1371
+KA ++ EL+K K +S ++++ + +++ + LE ++R+ +
Sbjct: 8538 IELKADLLQQQTELKKTKADLKQQMDDLEKTRSEILKHEKDTDSKTRELELIEIQRQKDD 8597
Query: 1370 LDT------MDAIHEEELRKEKV-DKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLN-- 1218
L+T ++ E LR E V +K L + + ++ EK D+ +N
Sbjct: 8598 LETRIQKLTLEKRDLEVLRSEIVLEKKDLDQKMKQVIRKRDEMEKIRSDIANATEEINRE 8657
Query: 1217 ----DALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQE-------------GHEAEIE 1089
+ L+ ++ + + L +R ++LE + ++ TD + + E+E
Sbjct: 8658 RQELEILRNNVQSARHDFELLLERTANLEDEESAATDIERLVLEVVKIREMVRNLKGEME 8717
Query: 1088 RKLEASNLTHNDELHKEKDDKKSIMNDLDRVKAEKQVLESKVS-------DLETTYSTLN 930
R++E S + DE K + + + D+ +++ L ++ +LE + L
Sbjct: 8718 RRMEKSKV-EIDEKEIFKSEIQRFIQDIGQIRENLGGLGEEIEKTRRDKRELEKMRAELA 8776
Query: 929 NELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLK 750
+ Q++ E ER+ LE +K + + D+E +E K++ + Q K
Sbjct: 8777 EKQQEQESMREMLHKEREELEQLKDEINREKEDVEIRRELVEAVIDKEEMKEFTDIQKYK 8836
Query: 749 KRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLN-KESKEKQDLEKRVLEL 585
+ + + E +LT K+ L +N + ++ + E++N + K++ +LE EL
Sbjct: 8837 EELQSVTE--ELLT--KKRDLDQLNSDVQDLRQTIEEINIQHGKKRAELEGIGFEL 8888
Score = 62.4 bits (150), Expect = 2e-06
Identities = 121/544 (22%), Positives = 221/544 (40%), Gaps = 48/544 (8%)
Frame = -3
Query: 2081 QALESKVSVFEAAIATLNDELLNEKDDKKCIVNDRNILEAAKQ--ALEYKVADLEAAK-- 1914
Q L+++ + E + T ND LL E +K+ ND + E K+ ALE + D+ K
Sbjct: 14066 QLLQTEKEILEKS-KTEND-LLREDLEKQRKRNDLTLQELRKEKMALEQMITDITKEKDA 14123
Query: 1913 -TTLNDELERKKDD--NNAIIKKALDKRISDLKADAPQRD-----QEDDMNALIXXXXXX 1758
+L +E+ K+ + N K + DL+ R Q+ +++ I
Sbjct: 14124 VASLQNEVSLKQHELKNKETELDEQRKEMDDLRMQLEMRQNSTNKQQQEVDVFIVENMKM 14183
Query: 1757 XXXXXXXXKIVSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKS 1578
++LE +L EE ++ +D+ P K + LE +
Sbjct: 14184 R----------NDLESMKTLLDEERRQLQDNIKTFEDQKNVLHPSKTDAVQQTDELEKFT 14233
Query: 1577 RSLK---EHFLREEEDEVLERSASNLAIMKAIRE--------EELRKEKDGKSALVENGE 1431
+K EH +E E E N I+K+ E E ++E GK A +E+ E
Sbjct: 14234 TDIKTEKEHVEKERE----EIDVLNKEIIKSKEELQSLNLEIEMFKQEIAGKRAQIESLE 14289
Query: 1430 GCEAE----KQGLEKTVLERRASNLDTMDAIHEEELRKE-KVDKSALTENGEGCEAEKQG 1266
A+ ++ V + ++ + E EL+ + K+ L E EAEK
Sbjct: 14290 QLRADLLAGADDIKTLVQTEKQMAIEDTEKKTEVELQMNLQKQKNELEELRNTIEAEKHQ 14349
Query: 1265 PEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIER 1086
E + L+ + D + + +E+ LEK S+L + L + + + E+ER
Sbjct: 14350 VENRKIMLDKQQKEVEDIMTV----IKSERDVLEKEKSELNKLSHVLNEKVQREQEELER 14405
Query: 1085 KLEASNLTHNDELHKEKDDKKSIMNDLDRVKAEKQVLESKVSDLETTYSTLNNELQQKM- 909
LE KE+DD I N +++EKQ +E + ++L+ + + ++ +
Sbjct: 14406 LLE-----------KERDD---IENCKKIIESEKQSIERERAELKRLKEEVEVQHERTLL 14451
Query: 908 -DDNEAFLNERDGLEA-----------VKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAE 765
D E++ LE +K+ ++++ +L+ +IE K +++ + E
Sbjct: 14452 QQDKNMIQKEKEHLEGEKARTTEEIHNLKEEIKRKSSELDMLNKEIEAKRQEEELHGLPE 14511
Query: 764 ----KQTLKKRISELEEAI--SILTDKAKKL-LKDINIWLSEVTELQEDLNKESKEKQDL 606
+ LKK L E I TD ++K LK + T L E + + ++ L
Sbjct: 14512 EIEIEDHLKKEDDVLREEIIKKQQTDASQKFQLKTTSRDAETQTSLDEITKTDERRQRAL 14571
Query: 605 EKRV 594
E+ V
Sbjct: 14572 EETV 14575
Score = 62.0 bits (149), Expect = 2e-06
Identities = 117/582 (20%), Positives = 218/582 (37%), Gaps = 78/582 (13%)
Frame = -3
Query: 2081 QALESKVS-VFEAAIATLND--ELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKT 1911
Q LE+KV V + T D EL +E ++K I+ + N + Q L+ + E K+
Sbjct: 15117 QTLETKVQDVLQLTDYTTQDQEELHDEMENKMKIILELNEAKKDLQKLKEECRSAEEEKS 15176
Query: 1910 TLNDELERKKDDNNAIIKKALD-----KRISDLKADAPQ--------------------- 1809
+ + LER+++ + + L ++ +K + Q
Sbjct: 15177 VIMESLERRRNSLEKVQSEVLSLTQEIDHLAQIKTEMQQIEIKMQIQTRSVATQWETDVQ 15236
Query: 1808 ----RDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDKTALIKDL 1641
++ + + V+ LE L E+Q+ +D ++D+
Sbjct: 15237 IQQGQEATETTGHITKKSEEEISAKKTKQPTVTKLEDT---LTSEVQEMRDSLNKEMEDV 15293
Query: 1640 VAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNLAIMKAIRE-EELRKEK 1464
+ + + + +S ++ E F R E+ + E+S + +++ + E+L
Sbjct: 15294 ARMKTIMKMEKDQLEQAKSDIQTQMEEFERNMEEAMEEKSRNEEKLLQLTHDKEDLSNTL 15353
Query: 1463 DGKSALVENG----------------------EGCEAEKQGLEKTVLERRASNLDTMDAI 1350
D K+ +EN E E E L++T ER T D
Sbjct: 15354 DKKNKEIENNTETSLKKIAQLETTIVLMKKDKENIENELLQLKQTEQEREIQR-GTDDTS 15412
Query: 1349 HEEELRKEKVD-KSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQ 1173
+E E EKV K+ L +N E +K+ + L L D+ + D +R E Q
Sbjct: 15413 NEREKYDEKVTYKTELEDNKE----KKKPDRDSSLKLTDA-----DSAKTDGER---EAQ 15460
Query: 1172 ALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASNLTHNDELHKEKDDKKSIMNDLDRVK 993
LE + D+ T +QE ELH E ++K I+ +L+ K
Sbjct: 15461 TLETKVQDVLQLTDDTTQDQE-------------------ELHDEMENKMKIILELNEAK 15501
Query: 992 AEKQVLESKVSDLETTYSTLNNELQQKMDDNE-------AFLNERDGLEAVKQGLEKRVL 834
+ Q L+ K E S + L+++ + E E + L +K +++
Sbjct: 15502 KDLQKLKEKCRSAEEEKSVIMESLERRRNSLEKVQSEVLTLTQEIEHLAQIKTEMQQIET 15561
Query: 833 DLEATIHDIEMKTGKDDDYNEAEKQTLKKR---ISELEEAISILTDKAKKLLKDINIWLS 663
++ + + D + ++ + R + EE IS K + K + S
Sbjct: 15562 KMQRQTRSVATQWETDVQIQQEGQEATETRGHITKKSEEEISAKKTKQPTVTKLEDTLTS 15621
Query: 662 EVTELQEDLNKESK-----------EKQDLEKRVLELTSKLE 570
EV E+++ LNKE + EK LE+ +L ++E
Sbjct: 15622 EVQEMRDSLNKEMEDVERMKTMMKMEKDQLEQAKSDLQRQME 15663
Score = 60.5 bits (145), Expect = 6e-06
Identities = 105/514 (20%), Positives = 211/514 (41%), Gaps = 39/514 (7%)
Frame = -3
Query: 1985 NDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKALDKRISDLKADAPQR 1806
++ ++ EA Q AD+E ELE+ KD+ K + K DL+ +
Sbjct: 1701 DELSLREATLQTATQTTADMELQLELQKQELEQTKDEMER-TKLEVQKGWVDLQTQIAES 1759
Query: 1805 DQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDKTALIKDLVAAEP 1626
++++M + +++ + ++ E+ E D K L K+ E
Sbjct: 1760 REKEEMVRI---------ELEKARDVLNRIRQDVET--EKQTMEADLKFTLAKEFENLEA 1808
Query: 1625 GKRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNLAIMKAIREEELRKEKDGKSAL 1446
++ + + LE+ L + E +ERS N+ +E + ++ L
Sbjct: 1809 QRKMMEDEKRALENMKYEL------QRESGYIERSKHNM-------HDERQNMENWAEKL 1855
Query: 1445 VENGEGCEAEKQGLE--KTVLERRASNLDTMDAIHEEELRKEKVDKSAL-------TENG 1293
+ E E ++ ++ +T R +L+ + ++E L + K L ++
Sbjct: 1856 KQEWEELEKKRHDMQQLQTERSREIKDLENLRELNELTLNQIKTKSDVLEKISELNSQQK 1915
Query: 1292 EGCEAEKQGPEKTVLDLEPTIPSLN---DALQRDLDRVMAEKQALEKRCSDLEAKNASLT 1122
+ E EK + DL+ LN +Q + V EK L+K ++ + +
Sbjct: 1916 DEIENEKSKIKIREYDLQQMQTDLNRQQKEMQDIQNAVFMEKSELKKSQDEIAEQLKQVG 1975
Query: 1121 DNQEGHEAE-----------IERKLEAS-NLTH--NDELHKEKDDKKSIMNDLDRVKAEK 984
D + + E IE+KL+ ++TH N EL K KK ++N+ ++ +
Sbjct: 1976 DMMQFTQNEKDNLDRERAAIIEQKLQMERDMTHLLNRELESLKLVKKEVLNEKRLLEDCR 2035
Query: 983 QVLESKVSDLETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGL----EKRVLDLEA-- 822
L + DLE L E ++ ++ E+D LE+V Q L EK +D A
Sbjct: 2036 ISLMRDMQDLEQMKINLEREKEEMQLQRQSIAEEKDKLESVLQTLAEDTEKLRIDTLAEK 2095
Query: 821 -TIHD--IEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTE 651
+ D +E++ +D+ N AE+ KR E + I + +K + KD+ L +
Sbjct: 2096 QKLEDAAVELQKERDEIMNIAEE---TKRKREDVDKIRVGIEKQEITFKDLKADLQKEAA 2152
Query: 650 LQED----LNKESKEKQDLEKRVLELTSKLEKCI 561
+ E+ + K+ + +D+E ++ + +++ +
Sbjct: 2153 IVENQRQAVQKDIQNVKDMEVQIQKERQYMDRLV 2186
>ref|XP_012262786.1| PREDICTED: myosin-2 heavy chain-like isoform X2 [Athalia rosae]
Length = 1620
Score = 102 bits (254), Expect = 1e-18
Identities = 127/542 (23%), Positives = 246/542 (45%), Gaps = 55/542 (10%)
Frame = -3
Query: 2027 DELLNEKDDKKCIVN----DRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAI- 1863
D L +E+D + +N + + L+A L+ +V LEA L E ++ K+D +A+
Sbjct: 555 DALKDERDKLRNEINALKAENDKLQAEVNKLKAEVERLEAENGRLKAEFQKLKNDYDALK 614
Query: 1862 -----IKKAL---DKRISDLKAD--------APQRDQEDDMNALIXXXXXXXXXXXXXXK 1731
+KK+L + RI L+A+ A ++Q D + +
Sbjct: 615 SENDDLKKSLADAEGRIKSLEAEKANLLNKIAELKNQIDRLQGELAAEKAAKDAALQELA 674
Query: 1730 IVSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSL--KEHF 1557
+ + +L ++L+ E+D A + DL +N+ + L+SK +L +
Sbjct: 675 AIKSELKALLAEMDKLKAERDKLKAAVDDLTKQ---LSQLNDDLDQLKSKYAALLAENDK 731
Query: 1556 LREEEDEVL---ERSASNLAIMKAIREE---ELRKEKDGKSALVENGEGCEAEKQGLE-- 1401
L+ E D + +R ++L +KA + E K K+ + L ++ E++ +GLE
Sbjct: 732 LKGEVDRLKGENDRLKNDLDKIKAELDNLKAENAKLKEENAKLKKDLSAAESKIKGLENQ 791
Query: 1400 -KTVLERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPS 1224
K E +A + +DA+ K++VDK G+ AE+ E + +L+
Sbjct: 792 IKACEEEKARLRNEIDAL------KDQVDKL-----GKELAAERAAKEAALRELDALKNE 840
Query: 1223 LNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIER-------------K 1083
L+ AL+ +LD+V E L+ L+A+N +L + + E++R
Sbjct: 841 LS-ALRAELDKVRGENTRLKGELDKLKAENEALKADNNKMKGELDRLNAQVAKLLGDIDA 899
Query: 1082 LEASNLTHNDELHKEKDDKKSIM--ND-----LDRVKAEKQVLESKVSDLETTYSTLNNE 924
L+A N +L K D+ K++ ND L+++KAE L+ +++ + + L E
Sbjct: 900 LKAENAKLKGDLDKLNDEIKALRAENDKLKAELEQMKAENAKLKDQLASAQAEMAKLKEE 959
Query: 923 LQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGK---DDDYNEAEKQTL 753
L + +N+A E ++ L + L+ + ++ + K + D AE + L
Sbjct: 960 LDKLKSENDALRGELSKMKGELDKLNAEIAKLQKDLDALKAENAKLKDELDKLSAENKEL 1019
Query: 752 KKRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLELTSKL 573
+ ++L+ + L + +KL KD+ ++EV +L+EDL+K E L+ ++ S+L
Sbjct: 1020 RSENAKLKGELDSLKSENEKLKKDLAAAMAEVAKLKEDLDKLQAENDALKAENAKIKSEL 1079
Query: 572 EK 567
+K
Sbjct: 1080 DK 1081
Score = 90.5 bits (223), Expect = 5e-15
Identities = 127/530 (23%), Positives = 229/530 (43%), Gaps = 21/530 (3%)
Frame = -3
Query: 2075 LESKVSVFEAAIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDE 1896
L+ +++ +AA EL K + K ++ + + L+A + L+ V DL + LND+
Sbjct: 655 LQGELAAEKAAKDAALQELAAIKSELKALLAEMDKLKAERDKLKAAVDDLTKQLSQLNDD 714
Query: 1895 LERKKDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNL 1716
L++ K A++ + DK LK + + E+D + +
Sbjct: 715 LDQLKSKYAALLAEN-DK----LKGEVDRLKGENDR----------------LKNDLDKI 753
Query: 1715 EVNILILHEELQKEKDDKTALIKDLVAAEPG-KRTVNEIVSHLESKSRSLKEHFLREEED 1539
+ + L E K K++ L KDL AAE K N+I + E K+R LR E D
Sbjct: 754 KAELDNLKAENAKLKEENAKLKKDLSAAESKIKGLENQIKACEEEKAR------LRNEID 807
Query: 1538 EVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTM 1359
L+ L +EL E+ K A + + + E L + + R N
Sbjct: 808 -ALKDQVDKLG-------KELAAERAAKEAALRELDALKNELSALRAELDKVRGENTRL- 858
Query: 1358 DAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSL---NDALQRDLDRV 1188
+ EL K K + AL + + E V L I +L N L+ DLD++
Sbjct: 859 ----KGELDKLKAENEALKADNNKMKGELDRLNAQVAKLLGDIDALKAENAKLKGDLDKL 914
Query: 1187 -------MAEKQALEKRCSDLEAKNASLTDNQEGHEAEIER------KLEASNLTHNDEL 1047
AE L+ ++A+NA L D +AE+ + KL++ N EL
Sbjct: 915 NDEIKALRAENDKLKAELEQMKAENAKLKDQLASAQAEMAKLKEELDKLKSENDALRGEL 974
Query: 1046 HKEKDDKKSIMNDLDRVKAEKQVLESKVSDLETTYSTLNNELQQKMDDNEAFLNERDGLE 867
K K + + ++ +++ + L+++ + L+ L+ E ++ +N E D L+
Sbjct: 975 SKMKGELDKLNAEIAKLQKDLDALKAENAKLKDELDKLSAENKELRSENAKLKGELDSLK 1034
Query: 866 AVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLL 687
+ + L+K DL A + ++ K +D D +AE LK ++++ + L + +L
Sbjct: 1035 SENEKLKK---DLAAAMAEV-AKLKEDLDKLQAENDALKAENAKIKSELDKLKSENAELQ 1090
Query: 686 KDINIWLSEVTELQ---EDLNKES-KEKQDLEKRVLELTSKLEKCICGAR 549
K ++ +E L+ +DL K++ K K DL+ + E+ KL+ G+R
Sbjct: 1091 KALDSLKAENARLKSEVDDLKKDNEKLKNDLQNAIAEM-DKLKAESSGSR 1139
Score = 84.7 bits (208), Expect = 3e-13
Identities = 121/553 (21%), Positives = 228/553 (41%), Gaps = 50/553 (9%)
Frame = -3
Query: 2075 LESKVSVFEAAIATLNDELLNEKDDKKCIVNDRNI----LEAAKQALEYKVADLEAAKTT 1908
L ++ EA IA L +L+ DK ++ND L + L + + +
Sbjct: 190 LLQRIKDLEALIAMLRKQLV----DKDAVINDLQNQSFDLATENKRLSVDLDQMNVSYKA 245
Query: 1907 LNDELE------RKKDDNNAIIKKALDKRISDLKADAPQRDQEDDMN----ALIXXXXXX 1758
L DE++ +K+DD + + ++L +L + + D + +L
Sbjct: 246 LMDEVKAMKEELKKRDDKVSDLLRSLQASAIELLGMNRLQSEMDTLKPQLYSLELERDQL 305
Query: 1757 XXXXXXXXKIVSNLEVNILILHEELQKEKDDKT---------ALIKDLVAAEPG-KRTVN 1608
+VS I+ + EE K+K K + ++ L+ E KR ++
Sbjct: 306 VSELGKVRGVVSERNDQIIKILEE--KDKHVKALARTSNIIQSTVEPLMEQEAALKREID 363
Query: 1607 EIVSHLESKSRSLKEHFLREEEDEVLERSASNLAIMKAIREEE---------LRKEKDGK 1455
+ + R L E LR++ ++ +A +++ I+ E L + D
Sbjct: 364 GLKDRIAELERELAE--LRKKLAQLESENAEIPGLLEKIKNLEDELARLRAQLAEANDRI 421
Query: 1454 SALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAE 1275
L + +A+K LEK + E R M+ + EE + ++AL E G C AE
Sbjct: 422 RELEKEIAELKADKAQLEKDLAEARKE----MEKMREELAAERAAKEAALKELGN-CRAE 476
Query: 1274 KQGPEKTVLDLEPTIPSLN----------DALQRDLDRVMAEKQALEKRCSDLEAKNASL 1125
+ K + + +L DA + + D++ ++ + L+ L A+N L
Sbjct: 477 NERLNKELNAAKAEADNLRGEIERLKNALDAAKGEADKLRSDMEKLKNELDKLRAENDQL 536
Query: 1124 TDNQEGHEAEIERKLEASNLTHNDELHKEKDDKKSIMNDLDRVKAEKQVLESKVSDLETT 945
+ G AE ER E+ KD++ + N+++ +KAE L+++V+ L+
Sbjct: 537 KNQLAGLTAENERL--------RGEIDALKDERDKLRNEINALKAENDKLQAEVNKLKAE 588
Query: 944 YSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAE 765
L E + + + N+ D L++ L+K + D E I + EAE
Sbjct: 589 VERLEAENGRLKAEFQKLKNDYDALKSENDDLKKSLADAEGRIKSL-----------EAE 637
Query: 764 KQTLKKRISELEEAI-----SILTDKAKK--LLKDINIWLSEVTELQEDLNKESKEKQDL 606
K L +I+EL+ I + +KA K L+++ SE+ L +++K E+ L
Sbjct: 638 KANLLNKIAELKNQIDRLQGELAAEKAAKDAALQELAAIKSELKALLAEMDKLKAERDKL 697
Query: 605 EKRVLELTSKLEK 567
+ V +LT +L +
Sbjct: 698 KAAVDDLTKQLSQ 710
>ref|XP_012262776.1| PREDICTED: major antigen-like isoform X1 [Athalia rosae]
Length = 1710
Score = 102 bits (254), Expect = 1e-18
Identities = 127/542 (23%), Positives = 246/542 (45%), Gaps = 55/542 (10%)
Frame = -3
Query: 2027 DELLNEKDDKKCIVN----DRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAI- 1863
D L +E+D + +N + + L+A L+ +V LEA L E ++ K+D +A+
Sbjct: 645 DALKDERDKLRNEINALKAENDKLQAEVNKLKAEVERLEAENGRLKAEFQKLKNDYDALK 704
Query: 1862 -----IKKAL---DKRISDLKAD--------APQRDQEDDMNALIXXXXXXXXXXXXXXK 1731
+KK+L + RI L+A+ A ++Q D + +
Sbjct: 705 SENDDLKKSLADAEGRIKSLEAEKANLLNKIAELKNQIDRLQGELAAEKAAKDAALQELA 764
Query: 1730 IVSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSL--KEHF 1557
+ + +L ++L+ E+D A + DL +N+ + L+SK +L +
Sbjct: 765 AIKSELKALLAEMDKLKAERDKLKAAVDDLTKQ---LSQLNDDLDQLKSKYAALLAENDK 821
Query: 1556 LREEEDEVL---ERSASNLAIMKAIREE---ELRKEKDGKSALVENGEGCEAEKQGLE-- 1401
L+ E D + +R ++L +KA + E K K+ + L ++ E++ +GLE
Sbjct: 822 LKGEVDRLKGENDRLKNDLDKIKAELDNLKAENAKLKEENAKLKKDLSAAESKIKGLENQ 881
Query: 1400 -KTVLERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPS 1224
K E +A + +DA+ K++VDK G+ AE+ E + +L+
Sbjct: 882 IKACEEEKARLRNEIDAL------KDQVDKL-----GKELAAERAAKEAALRELDALKNE 930
Query: 1223 LNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIER-------------K 1083
L+ AL+ +LD+V E L+ L+A+N +L + + E++R
Sbjct: 931 LS-ALRAELDKVRGENTRLKGELDKLKAENEALKADNNKMKGELDRLNAQVAKLLGDIDA 989
Query: 1082 LEASNLTHNDELHKEKDDKKSIM--ND-----LDRVKAEKQVLESKVSDLETTYSTLNNE 924
L+A N +L K D+ K++ ND L+++KAE L+ +++ + + L E
Sbjct: 990 LKAENAKLKGDLDKLNDEIKALRAENDKLKAELEQMKAENAKLKDQLASAQAEMAKLKEE 1049
Query: 923 LQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGK---DDDYNEAEKQTL 753
L + +N+A E ++ L + L+ + ++ + K + D AE + L
Sbjct: 1050 LDKLKSENDALRGELSKMKGELDKLNAEIAKLQKDLDALKAENAKLKDELDKLSAENKEL 1109
Query: 752 KKRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLELTSKL 573
+ ++L+ + L + +KL KD+ ++EV +L+EDL+K E L+ ++ S+L
Sbjct: 1110 RSENAKLKGELDSLKSENEKLKKDLAAAMAEVAKLKEDLDKLQAENDALKAENAKIKSEL 1169
Query: 572 EK 567
+K
Sbjct: 1170 DK 1171
Score = 90.5 bits (223), Expect = 5e-15
Identities = 127/530 (23%), Positives = 229/530 (43%), Gaps = 21/530 (3%)
Frame = -3
Query: 2075 LESKVSVFEAAIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDE 1896
L+ +++ +AA EL K + K ++ + + L+A + L+ V DL + LND+
Sbjct: 745 LQGELAAEKAAKDAALQELAAIKSELKALLAEMDKLKAERDKLKAAVDDLTKQLSQLNDD 804
Query: 1895 LERKKDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNL 1716
L++ K A++ + DK LK + + E+D + +
Sbjct: 805 LDQLKSKYAALLAEN-DK----LKGEVDRLKGENDR----------------LKNDLDKI 843
Query: 1715 EVNILILHEELQKEKDDKTALIKDLVAAEPG-KRTVNEIVSHLESKSRSLKEHFLREEED 1539
+ + L E K K++ L KDL AAE K N+I + E K+R LR E D
Sbjct: 844 KAELDNLKAENAKLKEENAKLKKDLSAAESKIKGLENQIKACEEEKAR------LRNEID 897
Query: 1538 EVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTM 1359
L+ L +EL E+ K A + + + E L + + R N
Sbjct: 898 -ALKDQVDKLG-------KELAAERAAKEAALRELDALKNELSALRAELDKVRGENTRL- 948
Query: 1358 DAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSL---NDALQRDLDRV 1188
+ EL K K + AL + + E V L I +L N L+ DLD++
Sbjct: 949 ----KGELDKLKAENEALKADNNKMKGELDRLNAQVAKLLGDIDALKAENAKLKGDLDKL 1004
Query: 1187 -------MAEKQALEKRCSDLEAKNASLTDNQEGHEAEIER------KLEASNLTHNDEL 1047
AE L+ ++A+NA L D +AE+ + KL++ N EL
Sbjct: 1005 NDEIKALRAENDKLKAELEQMKAENAKLKDQLASAQAEMAKLKEELDKLKSENDALRGEL 1064
Query: 1046 HKEKDDKKSIMNDLDRVKAEKQVLESKVSDLETTYSTLNNELQQKMDDNEAFLNERDGLE 867
K K + + ++ +++ + L+++ + L+ L+ E ++ +N E D L+
Sbjct: 1065 SKMKGELDKLNAEIAKLQKDLDALKAENAKLKDELDKLSAENKELRSENAKLKGELDSLK 1124
Query: 866 AVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLL 687
+ + L+K DL A + ++ K +D D +AE LK ++++ + L + +L
Sbjct: 1125 SENEKLKK---DLAAAMAEV-AKLKEDLDKLQAENDALKAENAKIKSELDKLKSENAELQ 1180
Query: 686 KDINIWLSEVTELQ---EDLNKES-KEKQDLEKRVLELTSKLEKCICGAR 549
K ++ +E L+ +DL K++ K K DL+ + E+ KL+ G+R
Sbjct: 1181 KALDSLKAENARLKSEVDDLKKDNEKLKNDLQNAIAEM-DKLKAESSGSR 1229
Score = 84.7 bits (208), Expect = 3e-13
Identities = 121/553 (21%), Positives = 228/553 (41%), Gaps = 50/553 (9%)
Frame = -3
Query: 2075 LESKVSVFEAAIATLNDELLNEKDDKKCIVNDRNI----LEAAKQALEYKVADLEAAKTT 1908
L ++ EA IA L +L+ DK ++ND L + L + + +
Sbjct: 280 LLQRIKDLEALIAMLRKQLV----DKDAVINDLQNQSFDLATENKRLSVDLDQMNVSYKA 335
Query: 1907 LNDELE------RKKDDNNAIIKKALDKRISDLKADAPQRDQEDDMN----ALIXXXXXX 1758
L DE++ +K+DD + + ++L +L + + D + +L
Sbjct: 336 LMDEVKAMKEELKKRDDKVSDLLRSLQASAIELLGMNRLQSEMDTLKPQLYSLELERDQL 395
Query: 1757 XXXXXXXXKIVSNLEVNILILHEELQKEKDDKT---------ALIKDLVAAEPG-KRTVN 1608
+VS I+ + EE K+K K + ++ L+ E KR ++
Sbjct: 396 VSELGKVRGVVSERNDQIIKILEE--KDKHVKALARTSNIIQSTVEPLMEQEAALKREID 453
Query: 1607 EIVSHLESKSRSLKEHFLREEEDEVLERSASNLAIMKAIREEE---------LRKEKDGK 1455
+ + R L E LR++ ++ +A +++ I+ E L + D
Sbjct: 454 GLKDRIAELERELAE--LRKKLAQLESENAEIPGLLEKIKNLEDELARLRAQLAEANDRI 511
Query: 1454 SALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAE 1275
L + +A+K LEK + E R M+ + EE + ++AL E G C AE
Sbjct: 512 RELEKEIAELKADKAQLEKDLAEARKE----MEKMREELAAERAAKEAALKELGN-CRAE 566
Query: 1274 KQGPEKTVLDLEPTIPSLN----------DALQRDLDRVMAEKQALEKRCSDLEAKNASL 1125
+ K + + +L DA + + D++ ++ + L+ L A+N L
Sbjct: 567 NERLNKELNAAKAEADNLRGEIERLKNALDAAKGEADKLRSDMEKLKNELDKLRAENDQL 626
Query: 1124 TDNQEGHEAEIERKLEASNLTHNDELHKEKDDKKSIMNDLDRVKAEKQVLESKVSDLETT 945
+ G AE ER E+ KD++ + N+++ +KAE L+++V+ L+
Sbjct: 627 KNQLAGLTAENERL--------RGEIDALKDERDKLRNEINALKAENDKLQAEVNKLKAE 678
Query: 944 YSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAE 765
L E + + + N+ D L++ L+K + D E I + EAE
Sbjct: 679 VERLEAENGRLKAEFQKLKNDYDALKSENDDLKKSLADAEGRIKSL-----------EAE 727
Query: 764 KQTLKKRISELEEAI-----SILTDKAKK--LLKDINIWLSEVTELQEDLNKESKEKQDL 606
K L +I+EL+ I + +KA K L+++ SE+ L +++K E+ L
Sbjct: 728 KANLLNKIAELKNQIDRLQGELAAEKAAKDAALQELAAIKSELKALLAEMDKLKAERDKL 787
Query: 605 EKRVLELTSKLEK 567
+ V +LT +L +
Sbjct: 788 KAAVDDLTKQLSQ 800
>ref|XP_001312904.1| viral A-type inclusion protein [Trichomonas vaginalis G3]
gi|121894768|gb|EAX99974.1| viral A-type inclusion
protein, putative [Trichomonas vaginalis G3]
Length = 3748
Score = 102 bits (253), Expect = 2e-18
Identities = 111/518 (21%), Positives = 234/518 (45%), Gaps = 25/518 (4%)
Frame = -3
Query: 2048 AAIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNN 1869
A + LN++L ++ D+ +V L++AK E K +L+A +++DE+ + KD+
Sbjct: 522 AELNKLNEQLKSKMDE---MVKADQELQSAKDEHEAKKNELKAEIESVSDEISKLKDELE 578
Query: 1868 AIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVN--ILIL 1695
I D + DLK D +N L+ I +N E+N I++L
Sbjct: 579 VIP----DFEVDDLK---------DQLNELLKEKEELEKEK-----IKNNDELNSSIIML 620
Query: 1694 HEELQKEKDDKTALIKDLVAAEPGKRT--VNEIVSHLESKSRSLKEHFLREEEDEVLERS 1521
+E+QKEK +K D ++ E KR +N+ S L+ + SL+ + E D++ E
Sbjct: 621 KDEIQKEKANK-----DKISEEKNKRDKELNDEKSKLQDELDSLQLDEIENENDQLFE-- 673
Query: 1520 ASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHEE 1341
E E K K + ++ N + + +++ +E++ +L+ + +
Sbjct: 674 -----------EVEDLKSKVDDAKILYNDMVDKIDDLKQQRSKVEQKYKDLEKQNKEKSD 722
Query: 1340 ELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSL------NDALQRDLDRVMAE 1179
E+ K + S L E + K + ++ + N+ +Q +++++ E
Sbjct: 723 EIEKVSKEISELKEKLDNLNQFKDNTPELHQKVDAMNEQIVKKSQENEKIQEEMNKLNEE 782
Query: 1178 KQALEKRCSDLEAKN---ASLTDNQEGHEAEIERKLEASN---------LTHNDELHKEK 1035
Q LE ++E N ++ + + + +IE K +++ + ++ KE
Sbjct: 783 LQHLENEMEEIEVVNDERETIQEKIDNIKQQIEEKKKSNEEIQDIMNLLIEAENDAQKEL 842
Query: 1034 DDKKSIMNDLDRVKAEKQVLESKVSD---LETTYSTLNNELQQKMDDNEAFLNERDGLEA 864
DD + + + ++ Q L+ + D L + NN+LQ+++ D + L++ + +
Sbjct: 843 DDIEIVEAQSEEIRQRIQTLQDNLQDRKKLNNELTEQNNKLQKELKDLQNELDQTELVND 902
Query: 863 VKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLLK 684
+ L K++ +++ I++ + + + + NE + ++K EL+E I I+ DK+ KL
Sbjct: 903 DSESLNKKLDEIKEQINERKSQNENNTEQNEKLIEEIEKFAKELDE-IEIIEDKSDKLQA 961
Query: 683 DINIWLSEVTELQEDLNKESKEKQDLEKRVLELTSKLE 570
I+ ++ E Q++ + K DLE + KL+
Sbjct: 962 QISELQKQIDEKQKNNEQTDKSNNDLEHELQITKQKLD 999
Score = 85.1 bits (209), Expect = 2e-13
Identities = 114/521 (21%), Positives = 225/521 (43%), Gaps = 33/521 (6%)
Frame = -3
Query: 2030 NDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKA 1851
N++L E D K + D N + Q L+ ++++L+ E ++K + + + +
Sbjct: 2652 NEKLKEEIDALKEELKD-NKSQEENQQLKSQISELQ--------EQIKQKQNEISETENS 2702
Query: 1850 LDKRISDLKADAPQRDQE--DDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQK 1677
L +IS L+ + +++ E D N+L + L ++L+K
Sbjct: 2703 LKSQISQLQNELKEKESERGDKSNSLYKEIDSLKEKINNQEIENKADSSQLSDLLKDLKK 2762
Query: 1676 ---EKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLK---EHFLREEEDEVLERSAS 1515
E ++ IK ++ E K ++ LE + +SL E+ +E+ E+LE S
Sbjct: 2763 KLQELTEENETIKSKISEE--KEKSKSEMAKLEEEKKSLNKELENVNDDEDKEMLEGEVS 2820
Query: 1514 NLA----IMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIH 1347
+L + K I EE+ +K K L E + + L+K + +++
Sbjct: 2821 SLKETLNLKKQINEEQKQKLSQEKEKLTEELSQLN-DNEDLKKEIEQKK----------- 2868
Query: 1346 EEELRKEKVDKSALTENGE-----GCEAEKQGPE--KTVLDLEPTIPSLNDALQRDLDRV 1188
EEL K K D S L E + ++EKQ PE K + DL+ I + + D +
Sbjct: 2869 -EELEKLKNDSSLLQELQDLKKQIEEKSEKQNPELLKQIEDLKKEISEK----ESENDLI 2923
Query: 1187 MAEKQALEKRCSDLEAKNASLTDNQEGHE---AEIERKLEASNLTHNDELHKEKDDKKSI 1017
EK +E++ + L + L E + +++ ++ + ++ +N + + + I
Sbjct: 2924 TGEKNTVEQQYNKLVEQRKYLESTMEAAKKKVSDLRQQCDELSMKNNQFRIDNEKEFQEI 2983
Query: 1016 MNDLDRVKAEKQVLESKVSDLETT---YSTLNNE----LQQKMD----DNEAFLNERDGL 870
++ +K +++ L K ++ + Y+TL + QQK+D NE L
Sbjct: 2984 KKSIEEIKGQREQLAKKHNEDKRRAREYNTLARQKLTDAQQKLDAEKAKNENLLKMMSEQ 3043
Query: 869 EAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKL 690
E LEK DLE ++E + D+++ + + L+K+ EL++ L+ K K+
Sbjct: 3044 EKTVSNLEKESEDLEQKNKELEQQMTSTGDFSQDKIEELRKKKEELQKLNDELSQKQKQN 3103
Query: 689 LKDINIWLSEVTELQEDLNKESKEKQDLEKRVLELTSKLEK 567
++ N +E L ++ + +EK E+ KLE+
Sbjct: 3104 IEQSNSLQNEKVTLSNEIESLKSSTEAMEKESTEMEKKLEE 3144
Score = 84.3 bits (207), Expect = 4e-13
Identities = 131/625 (20%), Positives = 261/625 (41%), Gaps = 54/625 (8%)
Frame = -3
Query: 2081 QALESKVSVFEAAIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTT-- 1908
+ +E K +A I+ L ++ ++ + + N LE Q + K+ + + K
Sbjct: 950 EIIEDKSDKLQAQISELQKQIDEKQKNNEQTDKSNNDLEHELQITKQKLDSMSSVKNNSD 1009
Query: 1907 --------LNDELERKKDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXX 1752
+N E+E+ +D NN + ++ DK +L+ D +++ I
Sbjct: 1010 YLKSEIENVNKEIEKIRDTNNKLKQELQDKN-KELEEMTDIADNSEELKEKIDSVNEEIT 1068
Query: 1751 XXXXXXKIVSNLEVNILI--LHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKS 1578
+ +N ++ LI LHE+L+ + ++ + +++++E+++ + K
Sbjct: 1069 KR-----VANNTTIDELIRHLHEDLKNAEAKLQSIPHVDDNTDSLQKSLDEVLAQISQKQ 1123
Query: 1577 RSLKE------HFLREEEDEVLERSASNLAIMKAIREE----------ELRKEKDGKSAL 1446
R E ++E+E++ E +N+ + REE ++ ++K +
Sbjct: 1124 RENDELNDEISRLIQEKEEKTDE--LNNMETIPDKREEISSEIETVKSQIEEKKKNNEKI 1181
Query: 1445 VENGEGCEAEKQGLEKTVLERRASNLDTMDAIHEEELRKEKV------------------ 1320
E + E + L +T+ + S+ + E E K+++
Sbjct: 1182 AEENKKLAEELENLRQTLSKMETSDQPLENIQKEIETTKQEISEKQKELDELKQELEQIK 1241
Query: 1319 --DKSALTENGEGCEAEK-QGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSD 1149
D+S E E E K Q EK + E I N+ Q +LD + E Q LE+ +
Sbjct: 1242 DEDQSKADEISEEIENIKTQIDEKNKKNEE--IAKNNEEKQSELDEKLKELQDLEEIKDE 1299
Query: 1148 LEAKNASLTDNQEGHEAEIERKLEASNLTHNDELHKEKDDKKSIMNDLDRVKAEKQVLES 969
E N + + Q+ E E +++ + +N N+EL K K D + I N D V+ + +E
Sbjct: 1300 TEEINQQIEETQK--EIETKKQQKENNNKLNEELDKLKQDLEQIENVEDNVEKLTEEIEK 1357
Query: 968 KVSDLETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGK 789
SD+++ + LNN++++ NE E L ++K+ LEK + +E +I + K
Sbjct: 1358 VKSDIDSKHQ-LNNDIKEA---NEVVEEE---LNSLKEELEK-IEPVEDKSDEIRKEIVK 1409
Query: 788 DDDYNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQD 609
E +K T ISE E ++ K L D+ L E+ E ++D + E ++
Sbjct: 1410 IQKEIETKKAT-NCGISESNELLN-------KELNDLKNQLEEIAEEKDDSEEIKAEIEN 1461
Query: 608 LEKRV---LELTSKLEKCICGARDGLSTIKEAWMSDCMVPDNWVPFEDLVQGFSRKTSPL 438
L K + E + ++ ++ LS ++E + +V D ++ +
Sbjct: 1462 LHKSIEEKKEHNANTQQNNENMKEELSKLQEEFDQIEVVEDKAEEIHSEIEKLKSQIEEK 1521
Query: 437 DITKT--CDAVDISEDSTTNIQVDY 369
+ T +A DI + N+Q Y
Sbjct: 1522 NTTNNDIKEANDILNEELNNLQKQY 1546
Score = 82.4 bits (202), Expect = 1e-12
Identities = 108/517 (20%), Positives = 239/517 (46%), Gaps = 32/517 (6%)
Frame = -3
Query: 2030 NDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAII--K 1857
N E+ N+ D + ++L+ K+ L+ + E K+ +++E E+ K + + K
Sbjct: 2741 NQEIENKADSSQL----SDLLKDLKKKLQELTEENETIKSKISEEKEKSKSEMAKLEEEK 2796
Query: 1856 KALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQK 1677
K+L+K + ++ D + E ++++L L + I E+ QK
Sbjct: 2797 KSLNKELENVNDDEDKEMLEGEVSSL-----------------KETLNLKKQINEEQKQK 2839
Query: 1676 EKDDKTALIKDLVAAEPGKRTVNEI------VSHLESKSRSLKEHFLREEEDEVLERSAS 1515
+K L ++L + EI + L++ S L+E L++ + ++ E+S
Sbjct: 2840 LSQEKEKLTEELSQLNDNEDLKKEIEQKKEELEKLKNDSSLLQE--LQDLKKQIEEKSEK 2897
Query: 1514 -NLAIMKAIREEELRKE---KDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIH 1347
N ++K I E+L+KE K+ ++ L+ GE E+Q ++E+R TM+A
Sbjct: 2898 QNPELLKQI--EDLKKEISEKESENDLI-TGEKNTVEQQ--YNKLVEQRKYLESTMEAAK 2952
Query: 1346 EE--ELRKEKVDKSALTENGEGCEAEKQGPE--KTVLDLEPTIPSLNDALQRDLDRVMAE 1179
++ +LR++ D+ ++ N + EK+ E K++ +++ L D R
Sbjct: 2953 KKVSDLRQQ-CDELSMKNNQFRIDNEKEFQEIKKSIEEIKGQREQLAKKHNEDKRRAREY 3011
Query: 1178 KQALEKRCSDLEAK-NASLTDNQEGHEAEIERKLEASNLTHNDE----LHKEKDDKKSIM 1014
++ +D + K +A N+ + E++ SNL E +KE + + +
Sbjct: 3012 NTLARQKLTDAQQKLDAEKAKNENLLKMMSEQEKTVSNLEKESEDLEQKNKELEQQMTST 3071
Query: 1013 NDLDRVKAEKQVLESKVSDLETTYSTLNNELQQKMDDNEAFLNER-------DGLEAVKQ 855
D + K E+ L K +L+ L+ + +Q ++ + + NE+ + L++ +
Sbjct: 3072 GDFSQDKIEE--LRKKKEELQKLNDELSQKQKQNIEQSNSLQNEKVTLSNEIESLKSSTE 3129
Query: 854 GLEKRVLDLEATIHD----IEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLL 687
+EK ++E + + I K+ + +D + K+ +K +L++ ++ L +KAKK+
Sbjct: 3130 AMEKESTEMEKKLEEDKGIISEKSKEKEDLEKKSKEQQEKS-DKLKQEVAELQEKAKKIT 3188
Query: 686 KDINIWLSEVTELQEDLNKESKEKQDLEKRVLELTSK 576
+ ++T+L+ ++ + K+DLE+ + + ++K
Sbjct: 3189 TENTDLNDKITDLEISISNAERRKKDLEEEIEKSSAK 3225
Score = 81.6 bits (200), Expect = 2e-12
Identities = 121/521 (23%), Positives = 221/521 (42%), Gaps = 29/521 (5%)
Frame = -3
Query: 2075 LESKVSVFEAAIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDE 1896
L+ ++S E+ + E + +V R LE+ +A + KV+DL L+ +
Sbjct: 2909 LKKEISEKESENDLITGEKNTVEQQYNKLVEQRKYLESTMEAAKKKVSDLRQQCDELSMK 2968
Query: 1895 LERKKDDNNAIIKKALDKRISDLKADAPQ---RDQEDDMNALIXXXXXXXXXXXXXXKIV 1725
+ + DN ++ + K I ++K Q + ED A
Sbjct: 2969 NNQFRIDNEKEFQE-IKKSIEEIKGQREQLAKKHNEDKRRAR------------------ 3009
Query: 1724 SNLEVNILI------LHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKE 1563
E N L ++L EK L+K + E + VS+LE +S L
Sbjct: 3010 ---EYNTLARQKLTDAQQKLDAEKAKNENLLKMMSEQE-------KTVSNLEKESEDL-- 3057
Query: 1562 HFLREEEDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKT---- 1395
E++++ LE+ ++ + EELRK+K+ L N E + +KQ +E++
Sbjct: 3058 ----EQKNKELEQQMTSTGDFSQDKIEELRKKKEELQKL--NDELSQKQKQNIEQSNSLQ 3111
Query: 1394 --------VLERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLE 1239
+E S+ + M+ E +K + DK ++E + EK+ EK + +
Sbjct: 3112 NEKVTLSNEIESLKSSTEAMEKESTEMEKKLEEDKGIISEKSK----EKEDLEKKSKEQQ 3167
Query: 1238 PTIPSLNDA---LQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASN 1068
L LQ ++ E L + +DLE ++ ++ E EIE+ S
Sbjct: 3168 EKSDKLKQEVAELQEKAKKITTENTDLNDKITDLEISISNAERRKKDLEEEIEKSSAKSL 3227
Query: 1067 LTHNDELHKEKDDKKSIMNDLDRV-KAEKQVLESKVSDLETTYSTLNNELQQKMDDNEAF 891
EL + + KK + ++ + K + LES +S LE +L E+Q N +
Sbjct: 3228 QEKEKELEEIAEKKKKEVREMKKQHKQNIRSLESSISLLEQDIKSL-EEIQ-----NSSK 3281
Query: 890 LNERDGLEAVKQGLEKRVLDLEATIHDIE-MKTGKDDDYNEAEKQTLK--KRISELEEAI 720
+E++GL Q L+++V DL+ ++E + +D + + EK+ L+ K +SE+ I
Sbjct: 3282 KSEQEGL----QLLDEKVADLKIKKFELEDIIADRDSELKKWEKELLEKNKELSEVNRQI 3337
Query: 719 SILT-DKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEK 600
L DK ++ +DI E+ ++ LN + E D E+
Sbjct: 3338 RALKGDKIDQIKEDIKDIDEEIESKKKKLNLNTVEDNDEEE 3378
Score = 80.9 bits (198), Expect = 4e-12
Identities = 126/542 (23%), Positives = 226/542 (41%), Gaps = 81/542 (14%)
Frame = -3
Query: 1955 QALEYKVADLEAAKTT--LNDELERKKDDNNAIIKKALDKRISDLKAD-APQRDQEDDMN 1785
Q +EYK + K L +LE +++N ++A + + +LKA A +R Q D N
Sbjct: 2235 QEMEYKNYNESLTKILDKLKVKLEEVEEENRNEDERA--EEVENLKAQIASKRKQNDAEN 2292
Query: 1784 ALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNE 1605
+ + NL+ N I EE+++ +D I E K + +
Sbjct: 2293 EKLSQEINKLKEE------LQNLQENTEI--EEMKQTVEDLKTQISVFGDPEQEKIKLQK 2344
Query: 1604 IVSHLESKSRSLKEHFLREEEDEVLERSASNLAIMKAIREE--ELRKEKDG-KSALVENG 1434
+ L K+ L E ++E++ L NL +K+ E +L +E+DG + LVE
Sbjct: 2345 EIDELTEKTEKLAE---ADDENDKLREQIENLKNVKSRDVEIIDLGEEEDGERQQLVEEL 2401
Query: 1433 EGCEAEKQGLEKT----------------VLERRASNLDTM---DAIHE--------EEL 1335
+ E + L+ T + E +ASN D D + E E +
Sbjct: 2402 NKLKEEYEQLQNTDDINDLKQEVIDLSKQIDEIKASNKDAQTKSDLLKELSQLNSQIENI 2461
Query: 1334 RKEKVDKSALTENGEGCEA-----EKQGPEKTVLDLEPTIP---SLNDALQRDLDRVMAE 1179
+E+ DK + + E ++ + + EK + DL+ + SL + L+ D+ E
Sbjct: 2462 IQEEEDKEEIRSHIEEIKSLLDNKQSEEDEKELDDLKKQLEDKQSLINKLKEDIKLTKEE 2521
Query: 1178 KQALEKRCSDLEAKNASLTDNQEGH----------EAEIER------KLEASNLTHNDEL 1047
+ +K DLE + L + E E EIER + + N D+L
Sbjct: 2522 NEKAQKNIDDLEQEFDDLNNEYEEESQFDEERKLLETEIERLKQLISEKKTQNKEKTDKL 2581
Query: 1046 HKEKDDKKSIMNDLDRVKAEKQVLESKVSDLETTYST--------------------LNN 927
KE +D +N L+ +E + L+S++ +L ++ LNN
Sbjct: 2582 FKEINDLTEELNSLED-DSENKELQSQIDELNEQINSVKEESNPQQTKENLQKELDDLNN 2640
Query: 926 ELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKK 747
+LQQ ++D E ++ ++A+K+ L+ D+ ++ E Q LK
Sbjct: 2641 KLQQMIEDEEENEKLKEEIDALKEELK--------------------DNKSQEENQQLKS 2680
Query: 746 RISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQD----LEKRVLELTS 579
+ISEL+E I K ++ + N S++++LQ +L ++ E+ D L K + L
Sbjct: 2681 QISELQEQIK---QKQNEISETENSLKSQISQLQNELKEKESERGDKSNSLYKEIDSLKE 2737
Query: 578 KL 573
K+
Sbjct: 2738 KI 2739
Score = 77.8 bits (190), Expect = 4e-11
Identities = 132/580 (22%), Positives = 246/580 (42%), Gaps = 30/580 (5%)
Frame = -3
Query: 2027 DELLNEKDDKKCIVNDRNIL--EAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKK 1854
DE+ E ++ K ++++N E AK E K ++L+ L D LE KD+ I +
Sbjct: 1249 DEISEEIENIKTQIDEKNKKNEEIAKNN-EEKQSELDEKLKELQD-LEEIKDETEEI-NQ 1305
Query: 1853 ALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKE 1674
+++ +++ Q++ + +N + + N+E N+ L EE++K
Sbjct: 1306 QIEETQKEIETKKQQKENNNKLNEELDKLKQDLEQ-------IENVEDNVEKLTEEIEKV 1358
Query: 1673 KDD---KTALIKDLVAA-EPGKRTVNEIVSHLES------KSRSLKEHFLREEEDEVLER 1524
K D K L D+ A E + +N + LE KS +++ ++ ++ E+ +
Sbjct: 1359 KSDIDSKHQLNNDIKEANEVVEEELNSLKEELEKIEPVEDKSDEIRKEIVKIQK-EIETK 1417
Query: 1523 SASNLAIMKAIREEELRKE-KDGKSALVE------NGEGCEAEKQGLEKTVLERRASNLD 1365
A+N I ++ E L KE D K+ L E + E +AE + L K++ E++ N +
Sbjct: 1418 KATNCGISES--NELLNKELNDLKNQLEEIAEEKDDSEEIKAEIENLHKSIEEKKEHNAN 1475
Query: 1364 TMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVM 1185
T E KE++ K L E + E + E+
Sbjct: 1476 TQQ---NNENMKEELSK--LQEEFDQIEVVEDKAEEI----------------------- 1507
Query: 1184 AEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASNLTHN-DELHKEKDDKKSIMND 1008
+EK S +E KN + D +E ++ E E +NL DE+ E+D + +
Sbjct: 1508 --HSEIEKLKSQIEEKNTTNNDIKEANDILNE---ELNNLQKQYDEIDVEEDKSEELSQ- 1561
Query: 1007 LDRVKAEKQVLESKVSDLETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLE---KRV 837
+V +++LE K S ET S N L++ ++ NE D +E V E K++
Sbjct: 1562 --KVTDLQKLLEEKKSQNETIKSGNENILKEL----QSLQNELDNIEVVSSSSEEGEKKI 1615
Query: 836 LDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEV 657
L+ I D + + + +NE +K +EL E I + DK+ L + I ++
Sbjct: 1616 EKLKQMISDKQKQNEETTKHNEELDNQIKDLENELNEIIPV-KDKSNDLQQQIEEIKDKI 1674
Query: 656 TELQE------DLNKESKEKQDLEKRVLELTSKLEKCICGARDGLSTIKEAWMSDCMVPD 495
T+ Q+ LN KE+ D K + + +E + + IK +
Sbjct: 1675 TDKQKKNEECSQLNTALKEEYDQLKSEFDNIAVIESKAEEIQQKIDEIKSE------IDQ 1728
Query: 494 NWVPFEDLVQGFS-RKTSPLDITKTCDAVDISEDSTTNIQ 378
++D+ +G + + + K + +++ ED T ++Q
Sbjct: 1729 KRKEYQDIKEGNDLLEEAYTEKQKELEQIEVVEDKTEDLQ 1768
Score = 76.3 bits (186), Expect = 1e-10
Identities = 106/506 (20%), Positives = 214/506 (42%), Gaps = 17/506 (3%)
Frame = -3
Query: 2036 TLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIK 1857
+LN+ + + ++ + RN ++ L+ ++A +E+ KT + DE++ ++D IK
Sbjct: 281 SLNEMIDLVAERRRALQELRNSQGKDEEKLKKQIAKVESEKTKIEDEIKHLQEDEEPQIK 340
Query: 1856 KALDK--------RISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNIL 1701
K D+ +I++ K ++ ED L N +
Sbjct: 341 KLKDRLDETTTKTQIAEKKLGEMRKTIEDSRQKLAQRRQNLIERRKELTNDAENTNTELQ 400
Query: 1700 ILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVLERS 1521
++ ++Q E D + + L VN++ S K +L+E ++++D L
Sbjct: 401 SINNQIQ-EIDSEFNKLNGL---------VNKVQSDHSKKKSALQEQLAQKQKD--LNDL 448
Query: 1520 ASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKTVLE----RRASNLDTMDA 1353
A KA RE E+ K D L+KT+ E + N+D +
Sbjct: 449 KRKQAEEKASREAEIAKIND-----------------QLQKTMKEYNDLNQPQNVDLKNE 491
Query: 1352 IHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQ 1173
I ++ + K +S + + E + + V +L LN+ L+ +D ++ Q
Sbjct: 492 I-DQATKDLKELESRVNKKREELFGKN---NQRVAELN----KLNEQLKSKMDEMVKADQ 543
Query: 1172 ALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASNLTHNDELHKEKDDKKSIMNDLDRVK 993
L+ + EAK L E EI + + + + E+ DD K +N+L + K
Sbjct: 544 ELQSAKDEHEAKKNELKAEIESVSDEISKLKDELEVIPDFEV----DDLKDQLNELLKEK 599
Query: 992 AEKQVLESKVSD-LETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATI 816
E + + K +D L ++ L +E+Q++ + + E++ + + ++ D ++
Sbjct: 600 EELEKEKIKNNDELNSSIIMLKDEIQKEKANKDKISEEKNKRDKELNDEKSKLQDELDSL 659
Query: 815 HDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDL 636
E++ D + E E LK ++ + + + + DK + D+ S+V + +DL
Sbjct: 660 QLDEIENENDQLFEEVE--DLKSKVDDAKILYNDMVDK----IDDLKQQRSKVEQKYKDL 713
Query: 635 NKESKEKQD----LEKRVLELTSKLE 570
K++KEK D + K + EL KL+
Sbjct: 714 EKQNKEKSDEIEKVSKEISELKEKLD 739
Score = 75.1 bits (183), Expect = 2e-10
Identities = 88/378 (23%), Positives = 177/378 (46%), Gaps = 15/378 (3%)
Frame = -3
Query: 1616 TVNEIVSHLESKSRSLKEHFLRE---EEDEVLERSASNLAIMKAIREEELRKEKDGKSA- 1449
++NE++ + + R+L+E LR +++E L++ + + K E+E++ ++ +
Sbjct: 281 SLNEMIDLVAERRRALQE--LRNSQGKDEEKLKKQIAKVESEKTKIEDEIKHLQEDEEPQ 338
Query: 1448 ---LVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHEEELRKEKVDK-SALTENGEGCE 1281
L + + + Q EK + E R + D+ + + R+ +++ LT + E
Sbjct: 339 IKKLKDRLDETTTKTQIAEKKLGEMRKTIEDSRQKLAQR--RQNLIERRKELTNDAENTN 396
Query: 1280 AEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALE-------KRCSDLEAKNASLT 1122
E Q + +++ LN + + +K AL+ K +DL+ K A
Sbjct: 397 TELQSINNQIQEIDSEFNKLNGLVNKVQSDHSKKKSALQEQLAQKQKDLNDLKRKQAEEK 456
Query: 1121 DNQEGHEAEIERKLEASNLTHNDELHKEKDDKKSIMNDLDRVKAEKQVLESKVSDLETTY 942
++E A+I +L+ + +ND + D K N++D+ + + LES+V+
Sbjct: 457 ASREAEIAKINDQLQKTMKEYNDLNQPQNVDLK---NEIDQATKDLKELESRVNKKR--- 510
Query: 941 STLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEK 762
EL K + A LN+ + E +K +++ V D E+++ KD+ +EA+K
Sbjct: 511 ----EELFGKNNQRVAELNKLN--EQLKSKMDEMVKA------DQELQSAKDE--HEAKK 556
Query: 761 QTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLELT 582
LK I + + IS L D+ + ++ D EV +L++ LN+ KEK++LEK ++
Sbjct: 557 NELKAEIESVSDEISKLKDELE-VIPDF-----EVDDLKDQLNELLKEKEELEKEKIKNN 610
Query: 581 SKLEKCICGARDGLSTIK 528
+L I +D + K
Sbjct: 611 DELNSSIIMLKDEIQKEK 628
Score = 71.6 bits (174), Expect = 3e-09
Identities = 96/526 (18%), Positives = 226/526 (42%), Gaps = 52/526 (9%)
Frame = -3
Query: 2033 LNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKK 1854
LN L E D K ++ ++E+ + ++ K+ ++++ E + K+ N+ ++++
Sbjct: 1687 LNTALKEEYDQLKSEFDNIAVIESKAEEIQQKIDEIKSEIDQKRKEYQDIKEGND-LLEE 1745
Query: 1853 ALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKE 1674
A ++ +L+ D+ +D+ LI +NLE + +E +K+
Sbjct: 1746 AYTEKQKELEQIEVVEDKTEDLQNLIDEITEQINSRKS-----NNLERQVS--NETFEKQ 1798
Query: 1673 KDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNLAIMKA 1494
+ DL + ++ E + + K +K+ + R +++ +S ++ +
Sbjct: 1799 LGQLKQELNDLPQTDDNSESLKEEIEETKKKLAMMKDEYQRMSDED---KSLTD----EL 1851
Query: 1493 IREEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDA-IHEEELRKEKVD 1317
IR E + + + ++EN +AEK+ + + +DT+ A + ++E +E ++
Sbjct: 1852 IRVESELNDLENQKNVLENETIVKAEKKMQNDNTIMDLRNKIDTLKAQLQQQEKPQEDIE 1911
Query: 1316 K-------------SALTENGEGC---EAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVM 1185
K + +++N E E E ++ +E D+L+ + V
Sbjct: 1912 KLKKEYQELKFQFDAKVSQNKEEVSHSENELHSLKEMYDKIEKVEQQQVDSLKSQILSVK 1971
Query: 1184 AEKQALEKRCSDLEAKNASLTDNQEGHEAEIER---KLEASNLTHN----DELHKEKDDK 1026
A+ K+ +++ + LT + + E+E+ K++ L +EL E D+K
Sbjct: 1972 AQIDDQNKKNEEMKKQIEKLTSEKSDAQNELEKAENKVDPDELVRLSEEIEELKLEADEK 2031
Query: 1025 KSIMNDL-----DRVKAEKQVLES----KVSDLETTYSTLNNELQQKMDDNEAFLNERDG 873
K ++ + + K++LE+ SD+ + + + +K +NEA +
Sbjct: 2032 KKQNEEVRSSLEEELSKYKEILENLKSDNQSDIHNQIDQIKDRINEKQQENEA---DNQK 2088
Query: 872 LEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKK 693
L+ + +K + ++ +I+ + ++ D N E +K I+E++E + +AKK
Sbjct: 2089 LQEIINNHKKLLENMNKEHEEIQKQIEQEVDKNNKEIDQKQKEINEVKEKLQ----QAKK 2144
Query: 692 LLKDINIWL-------------------SEVTELQEDLNKESKEKQ 612
+D + L SE+ L+++++K+ KE+Q
Sbjct: 2145 ENEDDKVELQRQIDNCGREIEKLQNAGDSEIDLLKQEIDKKEKERQ 2190
Score = 70.1 bits (170), Expect = 7e-09
Identities = 119/540 (22%), Positives = 221/540 (40%), Gaps = 50/540 (9%)
Frame = -3
Query: 2036 TLNDELLNEKDDKKCIVNDRNILE-------AAKQALEYKVADLEAAKTTLNDELERKKD 1878
+L DEL+ + + + N +N+LE K + + DL TL +L++++
Sbjct: 1846 SLTDELIRVESELNDLENQKNVLENETIVKAEKKMQNDNTIMDLRNKIDTLKAQLQQQEK 1905
Query: 1877 DNNAIIKKALDKRISDLK----ADAPQRDQE--DDMNALIXXXXXXXXXXXXXXKIVSNL 1716
I K L K +LK A Q +E N L + V +L
Sbjct: 1906 PQEDIEK--LKKEYQELKFQFDAKVSQNKEEVSHSENELHSLKEMYDKIEKVEQQQVDSL 1963
Query: 1715 EVNILIL----------HEELQKE----KDDKTALIKDLVAAEPGKRTVNEIVS------ 1596
+ IL + +EE++K+ +K+ +L AE K +E+V
Sbjct: 1964 KSQILSVKAQIDDQNKKNEEMKKQIEKLTSEKSDAQNELEKAE-NKVDPDELVRLSEEIE 2022
Query: 1595 --HLESKSRSLKEHFLREEEDEVLERSASNLAIMKAIREEELRKEKDG-KSALVENGEGC 1425
LE+ + + +R +E L + L +K+ + ++ + D K + E +
Sbjct: 2023 ELKLEADEKKKQNEEVRSSLEEELSKYKEILENLKSDNQSDIHNQIDQIKDRINEKQQEN 2082
Query: 1424 EAEKQGLEKTVLERRASNLDTMDAIHEEELR--KEKVDKSALTENGEGCEAEKQGPEKTV 1251
EA+ Q L++ ++ L+ M+ HEE + +++VDK N + + +++ +
Sbjct: 2083 EADNQKLQE-IINNHKKLLENMNKEHEEIQKQIEQEVDK-----NNKEIDQKQKEINEVK 2136
Query: 1250 LDLEPTIPSLND---ALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKL 1080
L+ D LQR +D E + L+ D E QE + E ER+
Sbjct: 2137 EKLQQAKKENEDDKVELQRQIDNCGREIEKLQ-NAGDSEIDLL----KQEIDKKEKERQQ 2191
Query: 1079 EASNLTHNDELHKEKDDKKSIMNDLDRVKAEKQV--LESKVSDLETTYSTLNNELQQKMD 906
H E++K K K N ++ K ++ L+ K+ E Y N L + +D
Sbjct: 2192 ATEQKQHEIEMYKAKLQHKEQENAVNAEKLHNEIENLKKKIDSQEMEYKNYNESLTKILD 2251
Query: 905 DNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEE 726
+ L E +E + ++R ++E +++ + N+AE + L + I++L+E
Sbjct: 2252 KLKVKLEE---VEEENRNEDERAEEVE----NLKAQIASKRKQNDAENEKLSQEINKLKE 2304
Query: 725 AISILTDKAKKLLKDINIWLSEVTELQEDLNKE-------SKEKQDLEKRVLELTSKLEK 567
+ L + N + E+ + EDL + +EK L+K + ELT K EK
Sbjct: 2305 ELQNLQE---------NTEIEEMKQTVEDLKTQISVFGDPEQEKIKLQKEIDELTEKTEK 2355
Score = 65.5 bits (158), Expect = 2e-07
Identities = 120/561 (21%), Positives = 229/561 (40%), Gaps = 82/561 (14%)
Frame = -3
Query: 1955 QALEYKVADLEAAKTTLNDELERKKDDNNAIIK--KALDKRISDLKADAPQ-RDQEDDMN 1785
+ +E K ++ + E+E KK N I + + L+K ++DLK + +++DD
Sbjct: 1394 EPVEDKSDEIRKEIVKIQKEIETKKATNCGISESNELLNKELNDLKNQLEEIAEEKDDSE 1453
Query: 1784 ALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQK--EKDDKTALIKDLVAAEPGKRTV 1611
+ + +N + N + EEL K E+ D+ +++D AE +
Sbjct: 1454 EIKAEIENLHKSIEEKKEHNANTQQNNENMKEELSKLQEEFDQIEVVED--KAEEIHSEI 1511
Query: 1610 NEIVSHLESKSRS---LKE-HFLREEEDEVLERSASNLAIMKAIREEELRKEKDGKSALV 1443
++ S +E K+ + +KE + + EE L++ + + + EE +K D + L
Sbjct: 1512 EKLKSQIEEKNTTNNDIKEANDILNEELNNLQKQYDEIDVEEDKSEELSQKVTDLQKLLE 1571
Query: 1442 ENGEGCEAEKQGLEKTV-----LERRASNLDTMDAIHEEELRK-EKVDKSALTENGEGCE 1281
E E K G E + L+ N++ + + EE +K EK+ + + + E
Sbjct: 1572 EKKSQNETIKSGNENILKELQSLQNELDNIEVVSSSSEEGEKKIEKLKQMISDKQKQNEE 1631
Query: 1280 AEKQGPE--KTVLDLE-------PTIPSLNDALQRDLDRV---MAEKQALEKRCSDLEAK 1137
K E + DLE P ND LQ+ ++ + + +KQ + CS L
Sbjct: 1632 TTKHNEELDNQIKDLENELNEIIPVKDKSND-LQQQIEEIKDKITDKQKKNEECSQLNTA 1690
Query: 1136 NASLTDNQ----------EGHEAEIERKLEASNLTHNDELHKEKDDKKSIMNDLDRVKAE 987
D E EI++K++ + D+ KE D K + L+ E
Sbjct: 1691 LKEEYDQLKSEFDNIAVIESKAEEIQQKIDEIK-SEIDQKRKEYQDIKEGNDLLEEAYTE 1749
Query: 986 KQ-------VLESKVSDLETTYSTLNNELQQKMDDN-------EAF----------LNER 879
KQ V+E K DL+ + ++ + +N E F LN+
Sbjct: 1750 KQKELEQIEVVEDKTEDLQNLIDEITEQINSRKSNNLERQVSNETFEKQLGQLKQELNDL 1809
Query: 878 ----DGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISIL 711
D E++K+ +E+ L A + D + +D E ++ +++LE ++L
Sbjct: 1810 PQTDDNSESLKEEIEETKKKL-AMMKDEYQRMSDEDKSLTDELIRVESELNDLENQKNVL 1868
Query: 710 TDKA-----KKLLKDINIW------------LSEVTELQEDLNKESKEKQDLEKRVLELT 582
++ KK+ D I L + + QED+ K KE Q+L+ +
Sbjct: 1869 ENETIVKAEKKMQNDNTIMDLRNKIDTLKAQLQQQEKPQEDIEKLKKEYQELKFQFDAKV 1928
Query: 581 SKLEKCICGARDGLSTIKEAW 519
S+ ++ + + + L ++KE +
Sbjct: 1929 SQNKEEVSHSENELHSLKEMY 1949
>ref|XP_001659192.1| AAEL001411-PA [Aedes aegypti] gi|108883254|gb|EAT47479.1|
AAEL001411-PA [Aedes aegypti]
Length = 1888
Score = 102 bits (253), Expect = 2e-18
Identities = 123/553 (22%), Positives = 229/553 (41%), Gaps = 49/553 (8%)
Frame = -3
Query: 2081 QALESKVSVFEAAIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLN 1902
Q LE+++ E + L+ E + + + + EAA+Q L+ + L+A +
Sbjct: 850 QDLEARIEEEEERVNALSSEKKKLQINIQDLEEQLEEEEAARQKLQLEKVQLDAKLKKME 909
Query: 1901 DELERKKDDNNAIIK--KALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKI 1728
+++ +D N ++K K L++R +DL + +++ A +
Sbjct: 910 EDVALTEDQNQKLLKEKKILEERANDLSQTLAEEEEKAKHLAKLKAKHEST--------- 960
Query: 1727 VSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSL--KEHFL 1554
++ LE +L H++ Q+ K + ++ K +NE +E + L +E L
Sbjct: 961 IAELEERLLKDHQQRQESDRSKRKIETEVADL---KEQINERRMQIEEMQQQLIKREEEL 1017
Query: 1553 REEEDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRAS 1374
+ + E SA+ A KA RE E S L E E EAEK K ++R
Sbjct: 1018 AQTLVRIDEESAAKAAAQKAQRELE--------SQLAEIQEDLEAEKLARSKAEKQKRDL 1069
Query: 1373 N----------LDTMDAIH-EEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIP 1227
N LD++D ++ELR ++ + A + + E E E V D+
Sbjct: 1070 NEELEALKNELLDSLDTTAAQQELRSKREQEVATLK--KTLEDESANHEGQVSDMRHKHA 1127
Query: 1226 SLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTD-----NQEGHEAEIERK------- 1083
++ L+ + K LEK LEA+NA L NQ E + RK
Sbjct: 1128 QEISSINEQLENLKKVKGGLEKAKQTLEAENADLATELRNVNQSRQENDRRRKQAETQIA 1187
Query: 1082 --------LEASNLTHNDELHKEKDDKKSIMNDLDRVKAEKQVLESKVSDLETTYS---- 939
+E + + D++ K + + ++I LD + + S++E+ +
Sbjct: 1188 ELQVKLAEVERARMELQDKVTKLQQESENITQQLDDAELKASAAIKSASNMESQLTEAQQ 1247
Query: 938 ----------TLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGK 789
L+++L+Q + EA + + E K+ EK++ +L TI +++ ++ +
Sbjct: 1248 LLEEETRQKLALSSKLRQLESEKEALQEQLEEDEEAKKNYEKKLAELNFTIQEMKRRSEE 1307
Query: 788 DDDYNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQD 609
D D ELEEA KK+ KDI + ++ ELQ ++ K K+
Sbjct: 1308 DSDI-----------AKELEEA-------KKKMNKDIEVLQRQILELQATNDRLDKSKKK 1349
Query: 608 LEKRVLELTSKLE 570
++ + + T +LE
Sbjct: 1350 IQSELEDATIELE 1362
Score = 75.5 bits (184), Expect = 2e-10
Identities = 109/497 (21%), Positives = 207/497 (41%), Gaps = 42/497 (8%)
Frame = -3
Query: 1931 DLEAAKTTLNDELERKKDDNNAIIKKALD-KRISDLKADAPQRDQEDDMNALIXXXXXXX 1755
D E+A + +R+ + A I++ L+ ++++ KA+ +RD +++ AL
Sbjct: 1025 DEESAAKAAAQKAQRELESQLAEIQEDLEAEKLARSKAEKQKRDLNEELEALKNELLDSL 1084
Query: 1754 XXXXXXXKIVSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGK-RTVNEIVSHLESKS 1578
++ S E + L + L+ E + + D+ + ++NE + +L+
Sbjct: 1085 DTTAAQQELRSKREQEVATLKKTLEDESANHEGQVSDMRHKHAQEISSINEQLENLKKVK 1144
Query: 1577 RSLKEHFLREEEDEVLERSASNLAI----MKAIREEELRKEKDGKSALVE-NGEGCEAEK 1413
L E+ + LE ++LA + R+E R+ K ++ + E + E E+
Sbjct: 1145 GGL------EKAKQTLEAENADLATELRNVNQSRQENDRRRKQAETQIAELQVKLAEVER 1198
Query: 1412 QGLEK----TVLERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLD 1245
+E T L++ + N+ + + EL+ KSA + EA++ E+T
Sbjct: 1199 ARMELQDKVTKLQQESENITQQ--LDDAELKASAAIKSASNMESQLTEAQQLLEEETRQK 1256
Query: 1244 LEPT-----IPSLNDALQRDLDRVMAEKQALEKRCSDL-----EAKNASLTDNQEGHEAE 1095
L + + S +ALQ L+ K+ EK+ ++L E K S D+ E E
Sbjct: 1257 LALSSKLRQLESEKEALQEQLEEDEEAKKNYEKKLAELNFTIQEMKRRSEEDSDIAKELE 1316
Query: 1094 IERKLEASNL-----------THNDELHKEKDDKKSIMNDLDRVKAEKQVLESKVSDLET 948
+K ++ ND L K K K I ++L+ E + +KV DLE
Sbjct: 1317 EAKKKMNKDIEVLQRQILELQATNDRLDKSK---KKIQSELEDATIELETQRTKVLDLEK 1373
Query: 947 TYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDI-----EMKTGKDD 783
+ L ++ +E ERD E + E +VL L + + +++T +
Sbjct: 1374 KQKNFDKVLAEEKAVSEQHAQERDAAEREAREKETKVLSLTRELDEAYEKIDDLETKRKA 1433
Query: 782 DYNEAE-----KQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKE 618
NE + + T K + ELE+A L + +L ++ EL++DL
Sbjct: 1434 LQNELDELANTQGTADKNVHELEKAKRALESQLAEL-------KAQNEELEDDLQLTEDA 1486
Query: 617 KQDLEKRVLELTSKLEK 567
K LE + L ++ E+
Sbjct: 1487 KLRLEVNMQALRAQFER 1503
Score = 67.8 bits (164), Expect = 4e-08
Identities = 79/332 (23%), Positives = 148/332 (44%), Gaps = 13/332 (3%)
Frame = -3
Query: 1490 REEELRKEKDGKSALVENGEGCEAE-KQGLEKTVLERRASNLDTMDAIHEEELRKEKVDK 1314
+E+ELR+ +D L + + E + +Q +E+ H E + +++
Sbjct: 782 KEDELRQIRDKLDNLSRSSQEYEKKFQQAIEEKT--------------HLAEQLQAEIEL 827
Query: 1313 SALTENGEG-CEAEKQGPEKTVLDLEPTIPSLND---ALQRDLDRVMAEKQALEKRCSDL 1146
A E G A KQ E+ + DLE I + AL + ++ Q LE++ +
Sbjct: 828 CAEAEEGRARLAARKQELEELMQDLEARIEEEEERVNALSSEKKKLQINIQDLEEQLEEE 887
Query: 1145 EAKNASLTDNQEGHEAEIERKLEASNLTH--NDELHKEKDDKKSIMNDLDRVKAEKQVLE 972
EA L + +A++++ E LT N +L KEK + NDL + AE++
Sbjct: 888 EAARQKLQLEKVQLDAKLKKMEEDVALTEDQNQKLLKEKKILEERANDLSQTLAEEEEKA 947
Query: 971 SKVSDLETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTG 792
++ L+ + + EL++++ + +R + K+ +E V DL+ I++ M+
Sbjct: 948 KHLAKLKAKHESTIAELEERLLKDH---QQRQESDRSKRKIETEVADLKEQINERRMQI- 1003
Query: 791 KDDDYNEAEKQTLKKRISELEEAISILTDK------AKKLLKDINIWLSEVTELQEDLNK 630
E +Q L KR EL + + + ++ A+K +++ S++ E+QEDL
Sbjct: 1004 ------EEMQQQLIKREEELAQTLVRIDEESAAKAAAQKAQRELE---SQLAEIQEDLEA 1054
Query: 629 ESKEKQDLEKRVLELTSKLEKCICGARDGLST 534
E + EK+ +L +LE D L T
Sbjct: 1055 EKLARSKAEKQKRDLNEELEALKNELLDSLDT 1086
Score = 66.2 bits (160), Expect = 1e-07
Identities = 110/532 (20%), Positives = 231/532 (43%), Gaps = 60/532 (11%)
Frame = -3
Query: 1985 NDRNILEAAKQALEYKVAD----LEAAKTTLNDELERKKDDNNAIIKKALDKRISDLKA- 1821
NDR L+ +K+ ++ ++ D LE +T + D LE+K+ + + ++ A +K +S+ A
Sbjct: 1340 NDR--LDKSKKKIQSELEDATIELETQRTKVLD-LEKKQKNFDKVL--AEEKAVSEQHAQ 1394
Query: 1820 --DAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDKTALIK 1647
DA +R+ + ++ + +LE L EL + + + K
Sbjct: 1395 ERDAAEREAREKETKVLSLTRELDEAYEK----IDDLETKRKALQNELDELANTQGTADK 1450
Query: 1646 DLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNLAIMKAIREEELRKE 1467
++ E KR + ++ L++++ L++ E+ ++ R N+ ++A E +++ +
Sbjct: 1451 NVHELEKAKRALESQLAELKAQNEELEDDLQLTEDAKL--RLEVNMQALRAQFERDVQAK 1508
Query: 1466 KDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHEEELRKEKVDKSALTENGEG 1287
+ E E +++GL K + + M+A +EE RK++ A + EG
Sbjct: 1509 E----------EQSEEKRRGLVKALRD--------MEAELDEE-RKQRAAAVAAKKKLEG 1549
Query: 1286 --------CEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQAL-------EKRCS 1152
E + E + + + DA+ RD + A K+ L E++
Sbjct: 1550 DLKDIEATLEMNNKVKEDALKQAKKLQAQVKDAI-RDAEEAKAAKEELAAVSKEAERKAK 1608
Query: 1151 DLEAKNASLTDN-------QEGHEAEIERKLEASNLTHN------DELHKEKDDKKSIMN 1011
LEA+ L+++ + EAE + LE N N DE + + ++
Sbjct: 1609 ALEAEVMQLSEDFASSERARRAAEAERDELLEEINSNSNKGSLMIDEKRRLEARIATLEE 1668
Query: 1010 DLDRVKAEKQVLESKVSDLETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLD 831
+L+ ++ ++L + + T + ELQ + +++ F N + GLE + L+ ++ +
Sbjct: 1669 ELEEEQSNAELLVDRNRKAQITIEQITTELQSEKSNSQKFENVKTGLERQNKELKAKLSE 1728
Query: 830 LE--------ATIHDIEMKTGKDDDYNEAE-KQTL--KKRISELEEAISILT-------- 708
LE A + +E K ++ E E K+ L +K +LE+ I LT
Sbjct: 1729 LETAQRTKVKAAMASLEAKIANLEEQLENETKERLGGQKANRKLEKKIKELTMNIEDERR 1788
Query: 707 --DKAKKLLKDIN----IWLSEVTELQEDLNKESKEKQDLEKRVLELTSKLE 570
D+ K+ ++ +N I + E +E++ KE +K+ ++ ++ E
Sbjct: 1789 HADQYKEQIEKMNNRMKILKRNLDEAEEEIQKEKTQKRKAQREYEDMLESHE 1840
>ref|XP_001659191.1| AAEL001411-PB [Aedes aegypti] gi|108883253|gb|EAT47478.1|
AAEL001411-PB [Aedes aegypti]
Length = 2001
Score = 102 bits (253), Expect = 2e-18
Identities = 123/553 (22%), Positives = 229/553 (41%), Gaps = 49/553 (8%)
Frame = -3
Query: 2081 QALESKVSVFEAAIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLN 1902
Q LE+++ E + L+ E + + + + EAA+Q L+ + L+A +
Sbjct: 963 QDLEARIEEEEERVNALSSEKKKLQINIQDLEEQLEEEEAARQKLQLEKVQLDAKLKKME 1022
Query: 1901 DELERKKDDNNAIIK--KALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKI 1728
+++ +D N ++K K L++R +DL + +++ A +
Sbjct: 1023 EDVALTEDQNQKLLKEKKILEERANDLSQTLAEEEEKAKHLAKLKAKHEST--------- 1073
Query: 1727 VSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSL--KEHFL 1554
++ LE +L H++ Q+ K + ++ K +NE +E + L +E L
Sbjct: 1074 IAELEERLLKDHQQRQESDRSKRKIETEVADL---KEQINERRMQIEEMQQQLIKREEEL 1130
Query: 1553 REEEDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRAS 1374
+ + E SA+ A KA RE E S L E E EAEK K ++R
Sbjct: 1131 AQTLVRIDEESAAKAAAQKAQRELE--------SQLAEIQEDLEAEKLARSKAEKQKRDL 1182
Query: 1373 N----------LDTMDAIH-EEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIP 1227
N LD++D ++ELR ++ + A + + E E E V D+
Sbjct: 1183 NEELEALKNELLDSLDTTAAQQELRSKREQEVATLK--KTLEDESANHEGQVSDMRHKHA 1240
Query: 1226 SLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTD-----NQEGHEAEIERK------- 1083
++ L+ + K LEK LEA+NA L NQ E + RK
Sbjct: 1241 QEISSINEQLENLKKVKGGLEKAKQTLEAENADLATELRNVNQSRQENDRRRKQAETQIA 1300
Query: 1082 --------LEASNLTHNDELHKEKDDKKSIMNDLDRVKAEKQVLESKVSDLETTYS---- 939
+E + + D++ K + + ++I LD + + S++E+ +
Sbjct: 1301 ELQVKLAEVERARMELQDKVTKLQQESENITQQLDDAELKASAAIKSASNMESQLTEAQQ 1360
Query: 938 ----------TLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGK 789
L+++L+Q + EA + + E K+ EK++ +L TI +++ ++ +
Sbjct: 1361 LLEEETRQKLALSSKLRQLESEKEALQEQLEEDEEAKKNYEKKLAELNFTIQEMKRRSEE 1420
Query: 788 DDDYNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQD 609
D D ELEEA KK+ KDI + ++ ELQ ++ K K+
Sbjct: 1421 DSDI-----------AKELEEA-------KKKMNKDIEVLQRQILELQATNDRLDKSKKK 1462
Query: 608 LEKRVLELTSKLE 570
++ + + T +LE
Sbjct: 1463 IQSELEDATIELE 1475
Score = 75.5 bits (184), Expect = 2e-10
Identities = 109/497 (21%), Positives = 207/497 (41%), Gaps = 42/497 (8%)
Frame = -3
Query: 1931 DLEAAKTTLNDELERKKDDNNAIIKKALD-KRISDLKADAPQRDQEDDMNALIXXXXXXX 1755
D E+A + +R+ + A I++ L+ ++++ KA+ +RD +++ AL
Sbjct: 1138 DEESAAKAAAQKAQRELESQLAEIQEDLEAEKLARSKAEKQKRDLNEELEALKNELLDSL 1197
Query: 1754 XXXXXXXKIVSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGK-RTVNEIVSHLESKS 1578
++ S E + L + L+ E + + D+ + ++NE + +L+
Sbjct: 1198 DTTAAQQELRSKREQEVATLKKTLEDESANHEGQVSDMRHKHAQEISSINEQLENLKKVK 1257
Query: 1577 RSLKEHFLREEEDEVLERSASNLAI----MKAIREEELRKEKDGKSALVE-NGEGCEAEK 1413
L E+ + LE ++LA + R+E R+ K ++ + E + E E+
Sbjct: 1258 GGL------EKAKQTLEAENADLATELRNVNQSRQENDRRRKQAETQIAELQVKLAEVER 1311
Query: 1412 QGLEK----TVLERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLD 1245
+E T L++ + N+ + + EL+ KSA + EA++ E+T
Sbjct: 1312 ARMELQDKVTKLQQESENITQQ--LDDAELKASAAIKSASNMESQLTEAQQLLEEETRQK 1369
Query: 1244 LEPT-----IPSLNDALQRDLDRVMAEKQALEKRCSDL-----EAKNASLTDNQEGHEAE 1095
L + + S +ALQ L+ K+ EK+ ++L E K S D+ E E
Sbjct: 1370 LALSSKLRQLESEKEALQEQLEEDEEAKKNYEKKLAELNFTIQEMKRRSEEDSDIAKELE 1429
Query: 1094 IERKLEASNL-----------THNDELHKEKDDKKSIMNDLDRVKAEKQVLESKVSDLET 948
+K ++ ND L K K K I ++L+ E + +KV DLE
Sbjct: 1430 EAKKKMNKDIEVLQRQILELQATNDRLDKSK---KKIQSELEDATIELETQRTKVLDLEK 1486
Query: 947 TYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDI-----EMKTGKDD 783
+ L ++ +E ERD E + E +VL L + + +++T +
Sbjct: 1487 KQKNFDKVLAEEKAVSEQHAQERDAAEREAREKETKVLSLTRELDEAYEKIDDLETKRKA 1546
Query: 782 DYNEAE-----KQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKE 618
NE + + T K + ELE+A L + +L ++ EL++DL
Sbjct: 1547 LQNELDELANTQGTADKNVHELEKAKRALESQLAEL-------KAQNEELEDDLQLTEDA 1599
Query: 617 KQDLEKRVLELTSKLEK 567
K LE + L ++ E+
Sbjct: 1600 KLRLEVNMQALRAQFER 1616
Score = 67.8 bits (164), Expect = 4e-08
Identities = 79/332 (23%), Positives = 148/332 (44%), Gaps = 13/332 (3%)
Frame = -3
Query: 1490 REEELRKEKDGKSALVENGEGCEAE-KQGLEKTVLERRASNLDTMDAIHEEELRKEKVDK 1314
+E+ELR+ +D L + + E + +Q +E+ H E + +++
Sbjct: 895 KEDELRQIRDKLDNLSRSSQEYEKKFQQAIEEKT--------------HLAEQLQAEIEL 940
Query: 1313 SALTENGEG-CEAEKQGPEKTVLDLEPTIPSLND---ALQRDLDRVMAEKQALEKRCSDL 1146
A E G A KQ E+ + DLE I + AL + ++ Q LE++ +
Sbjct: 941 CAEAEEGRARLAARKQELEELMQDLEARIEEEEERVNALSSEKKKLQINIQDLEEQLEEE 1000
Query: 1145 EAKNASLTDNQEGHEAEIERKLEASNLTH--NDELHKEKDDKKSIMNDLDRVKAEKQVLE 972
EA L + +A++++ E LT N +L KEK + NDL + AE++
Sbjct: 1001 EAARQKLQLEKVQLDAKLKKMEEDVALTEDQNQKLLKEKKILEERANDLSQTLAEEEEKA 1060
Query: 971 SKVSDLETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTG 792
++ L+ + + EL++++ + +R + K+ +E V DL+ I++ M+
Sbjct: 1061 KHLAKLKAKHESTIAELEERLLKDH---QQRQESDRSKRKIETEVADLKEQINERRMQI- 1116
Query: 791 KDDDYNEAEKQTLKKRISELEEAISILTDK------AKKLLKDINIWLSEVTELQEDLNK 630
E +Q L KR EL + + + ++ A+K +++ S++ E+QEDL
Sbjct: 1117 ------EEMQQQLIKREEELAQTLVRIDEESAAKAAAQKAQRELE---SQLAEIQEDLEA 1167
Query: 629 ESKEKQDLEKRVLELTSKLEKCICGARDGLST 534
E + EK+ +L +LE D L T
Sbjct: 1168 EKLARSKAEKQKRDLNEELEALKNELLDSLDT 1199
Score = 66.2 bits (160), Expect = 1e-07
Identities = 110/532 (20%), Positives = 231/532 (43%), Gaps = 60/532 (11%)
Frame = -3
Query: 1985 NDRNILEAAKQALEYKVAD----LEAAKTTLNDELERKKDDNNAIIKKALDKRISDLKA- 1821
NDR L+ +K+ ++ ++ D LE +T + D LE+K+ + + ++ A +K +S+ A
Sbjct: 1453 NDR--LDKSKKKIQSELEDATIELETQRTKVLD-LEKKQKNFDKVL--AEEKAVSEQHAQ 1507
Query: 1820 --DAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDKTALIK 1647
DA +R+ + ++ + +LE L EL + + + K
Sbjct: 1508 ERDAAEREAREKETKVLSLTRELDEAYEK----IDDLETKRKALQNELDELANTQGTADK 1563
Query: 1646 DLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNLAIMKAIREEELRKE 1467
++ E KR + ++ L++++ L++ E+ ++ R N+ ++A E +++ +
Sbjct: 1564 NVHELEKAKRALESQLAELKAQNEELEDDLQLTEDAKL--RLEVNMQALRAQFERDVQAK 1621
Query: 1466 KDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHEEELRKEKVDKSALTENGEG 1287
+ E E +++GL K + + M+A +EE RK++ A + EG
Sbjct: 1622 E----------EQSEEKRRGLVKALRD--------MEAELDEE-RKQRAAAVAAKKKLEG 1662
Query: 1286 --------CEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQAL-------EKRCS 1152
E + E + + + DA+ RD + A K+ L E++
Sbjct: 1663 DLKDIEATLEMNNKVKEDALKQAKKLQAQVKDAI-RDAEEAKAAKEELAAVSKEAERKAK 1721
Query: 1151 DLEAKNASLTDN-------QEGHEAEIERKLEASNLTHN------DELHKEKDDKKSIMN 1011
LEA+ L+++ + EAE + LE N N DE + + ++
Sbjct: 1722 ALEAEVMQLSEDFASSERARRAAEAERDELLEEINSNSNKGSLMIDEKRRLEARIATLEE 1781
Query: 1010 DLDRVKAEKQVLESKVSDLETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLD 831
+L+ ++ ++L + + T + ELQ + +++ F N + GLE + L+ ++ +
Sbjct: 1782 ELEEEQSNAELLVDRNRKAQITIEQITTELQSEKSNSQKFENVKTGLERQNKELKAKLSE 1841
Query: 830 LE--------ATIHDIEMKTGKDDDYNEAE-KQTL--KKRISELEEAISILT-------- 708
LE A + +E K ++ E E K+ L +K +LE+ I LT
Sbjct: 1842 LETAQRTKVKAAMASLEAKIANLEEQLENETKERLGGQKANRKLEKKIKELTMNIEDERR 1901
Query: 707 --DKAKKLLKDIN----IWLSEVTELQEDLNKESKEKQDLEKRVLELTSKLE 570
D+ K+ ++ +N I + E +E++ KE +K+ ++ ++ E
Sbjct: 1902 HADQYKEQIEKMNNRMKILKRNLDEAEEEIQKEKTQKRKAQREYEDMLESHE 1953