BLASTX 2.2.25 [Feb-01-2011]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= Papaver29_contig00004662
         (2687 letters)

Database: ./nr 
           77,306,371 sequences; 28,104,191,420 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

ref|XP_008219582.1| PREDICTED: DNA topoisomerase 2-binding prote...   890   0.0  
ref|XP_007019209.1| Topbp1, putative isoform 1 [Theobroma cacao]...   872   0.0  
ref|XP_007019210.1| Topbp1, putative isoform 2 [Theobroma cacao]...   870   0.0  
ref|XP_007227054.1| hypothetical protein PRUPE_ppa000738mg [Prun...   855   0.0  
ref|XP_012464226.1| PREDICTED: DNA topoisomerase 2-binding prote...   840   0.0  
ref|XP_007019212.1| Topbp1, putative isoform 4 [Theobroma cacao]...   836   0.0  
gb|KJB80623.1| hypothetical protein B456_013G107700 [Gossypium r...   819   0.0  
ref|XP_010320793.1| PREDICTED: DNA topoisomerase 2-binding prote...   818   0.0  
ref|XP_007019211.1| Topbp1, putative isoform 3 [Theobroma cacao]...   811   0.0  
ref|XP_006345369.1| PREDICTED: DNA topoisomerase 2-binding prote...   810   0.0  
ref|XP_009788828.1| PREDICTED: DNA topoisomerase 2-binding prote...   807   0.0  
ref|XP_014502699.1| PREDICTED: DNA topoisomerase 2-binding prote...   803   0.0  
ref|XP_009605009.1| PREDICTED: DNA topoisomerase 2-binding prote...   803   0.0  
ref|XP_009788827.1| PREDICTED: DNA topoisomerase 2-binding prote...   799   0.0  
ref|XP_008444199.1| PREDICTED: DNA topoisomerase 2-binding prote...   795   0.0  
emb|CDP16447.1| unnamed protein product [Coffea canephora]            792   0.0  
ref|XP_007019213.1| Topbp1, putative isoform 5 [Theobroma cacao]...   782   0.0  
ref|XP_012464227.1| PREDICTED: DNA topoisomerase 2-binding prote...   782   0.0  
ref|XP_009788829.1| PREDICTED: DNA topoisomerase 2-binding prote...   779   0.0  
ref|XP_011091797.1| PREDICTED: DNA topoisomerase 2-binding prote...   778   0.0  

>ref|XP_008219582.1| PREDICTED: DNA topoisomerase 2-binding protein 1 [Prunus mume]
          Length = 983

 Score =  890 bits (2301), Expect = 0.0
 Identities = 486/935 (51%), Positives = 616/935 (65%), Gaps = 59/935 (6%)
 Frame = -1

Query: 2687 KGCKLLGTELVISCGKENRALPKNKGFTCCLAMDGVKVLATGFDNKEKGKIEKLVTAMGG 2508
            KGC LLG + V SC  ++RALPK +GFTCCLAMDG KVLA+GF+  EK KIEKLVTAMGG
Sbjct: 69   KGCNLLGPQCVFSCANQHRALPK-QGFTCCLAMDGFKVLASGFEGDEKVKIEKLVTAMGG 127

Query: 2507 VFQTRAALDTDFVICKNVLSGKYKWGLQTLKKPVITINWLYQCWSEHRLVPHEPCRVLPF 2328
            V   +A+LD +FVI KNVL+GKYKW L TLKKP++TINWL QCW+EHR VP +  RVLPF
Sbjct: 128  VLHAKASLDVNFVIVKNVLAGKYKWALNTLKKPIVTINWLSQCWNEHRNVPQDSFRVLPF 187

Query: 2327 SGLTICFTRIAADVRKEMENLIVHNGGQYSGDLTRNCTHLISDAPEGDKYRVAQKWGHVR 2148
            SGL I  TRI AD RKE+E LI  NGG+YS +LT+ CTHLISD PEGDKY+VAQ+WGH+R
Sbjct: 188  SGLMISVTRIPADERKEIEKLITENGGKYSAELTKKCTHLISDVPEGDKYKVAQRWGHIR 247

Query: 2147 IVTKDWLRDSFNRKVYLPEDAYLVQGITMSANHVLKNELREKNYQDKKSTNSQSGPGPIA 1968
            IVT+ W   S +R+  L ED+Y VQG ++S+N  ++     +N Q   S N QS P  + 
Sbjct: 248  IVTRKWFDQSISRRACLNEDSYPVQGGSISSNKSVRGCFTLQNSQRSSSGNLQSVPPSVV 307

Query: 1967 ADS---------------EATLXXXXXXXXXXXXXIMKGEEGIEAPPPSKIEDKEET-LD 1836
            ADS               EAT+             ++K E+  +APP   +E K E  LD
Sbjct: 308  ADSNLTAAPYSGTMDSDLEATVSQNMTTMFSHAPHVVKNEDS-KAPP---LESKSEAYLD 363

Query: 1835 SCVADDSQSEDSGLYLSDCRILLVGFHAAEMRKLVNKVRRGGGSRYMAFNDRLTHIVVGT 1656
             CVADDSQSED+ LYLS+CRI LVGF A+EMR+LVN +RRGGGSRYM+FND+LTHIVVGT
Sbjct: 364  GCVADDSQSEDNDLYLSECRISLVGFKASEMRRLVNMIRRGGGSRYMSFNDKLTHIVVGT 423

Query: 1655 PTENERRELRRYTAAGVIYVVRAVWLDDCDREKKELPVSKRHVVPDLILPKDSVCPDKAT 1476
            P+E +++E+R + A GVI+VVR  WL+DCDREKKE+PV  +H+  DL+LP+ ++    +T
Sbjct: 424  PSEIQKKEVRGFAALGVIHVVRTTWLEDCDREKKEIPVLPKHIAYDLVLPEGALIGMTST 483

Query: 1475 KIGTRQGHNLITPPSVPDHLTQCFRPSM----------PREQTEERKTMEAS-------- 1350
              GT    +L + PS   H      P M          P    +  K+MEA+        
Sbjct: 484  IQGTISTTHL-SIPSDQLHGNTSAAPGMGSLEKKREKKPEINMKGDKSMEAAVGPSKWSK 542

Query: 1349 ----------------------KQESSMVKKNSSNIXXXXXXXXXXXFPLDRRAEIVEWI 1236
                                  + +SS+     S++           FP DRR +I++W+
Sbjct: 543  LPVINGKSKVQLNNTIDGRLTMQYDSSVQNGKESSVFKGRLFCFSNSFPEDRRGDIIQWV 602

Query: 1235 KQGGGEIVDGQSEFNVNFTVECHGLVTKAGNVSQSQTTIVSTHWIRSCLEDACMPDVGSH 1056
             QGGG++VDG  +  V+FT+ECHG++T   +V  +QTT VS+HWIRSCLED C+ DV SH
Sbjct: 603  NQGGGDVVDGYLKQKVHFTIECHGVIT--SSVDVAQTTYVSSHWIRSCLEDGCLLDVSSH 660

Query: 1055 IIYSPVPCKIPLPGFEAFRFCVSQYEEKDRLLLRNLCFVLGAKFTEKLSKKVTHLLCKFT 876
            I+Y+P+PC+IPLPGFE FRFCVSQYEEKDRLLLRNLCFVLGAKF EKL+KKVTHLLCKFT
Sbjct: 661  ILYAPLPCRIPLPGFENFRFCVSQYEEKDRLLLRNLCFVLGAKFGEKLTKKVTHLLCKFT 720

Query: 875  NGPKYEAACKWGMQTVTSEWISECIRQNAVVSAHPFRPKEMTAQDREAGLATMSQYTTQA 696
            NGPKY+AAC  G+  +T+EW+ EC+++N VV+   F PK++TA+DREAGL TMSQY TQA
Sbjct: 721  NGPKYQAACIKGIHPITAEWVYECVKKNKVVALDQFYPKKVTAEDREAGLCTMSQYPTQA 780

Query: 695  ARMIS---GEDVPSQSQGQSQFAMNSSRTFGKKSTNLSVEAEYPSATNKKRAKVSANNDK 525
             +MIS     + PSQSQ       +S    G ++ +L  EA  PS   KK A+VS ++ +
Sbjct: 781  VQMISAGNSSECPSQSQ---DLRTSSGENIGSRNDSLREEASEPSFCYKK-ARVSEDDGE 836

Query: 524  IDLLPLDVCANVSSCTMKSIKTSEGGNIRDDGSHDVPDVAAAIEDLLEESSKIQDMALSG 345
              LL   V   + +CT    K    G +    S  VPDVA+AIEDLLE++SKI D    G
Sbjct: 837  KGLLSSGVHLRIPACTAGDRKVKSSGEV----SQVVPDVASAIEDLLEQTSKIHDQKSPG 892

Query: 344  RTISDRSIFSPDHSIITQNPATSHSAIQISTSWLSRKEKQDDGNQCDSSSVQGVNEHRTY 165
            R++ D SIFSPD S + Q+ + SHS I +S  WL+R      GN+ D     G  +   Y
Sbjct: 893  RSLCDSSIFSPDCSALRQDHSDSHSVIGLSRHWLNRA-----GNKDDIHDPSGEQKAGFY 947

Query: 164  DGFSETQTESQVVVYEEDLSGRQMMIDRHRTRSSM 60
            DGFSETQTESQVV YEEDLSGRQM+IDR RTRSS+
Sbjct: 948  DGFSETQTESQVVGYEEDLSGRQMLIDRVRTRSSL 982


>ref|XP_007019209.1| Topbp1, putative isoform 1 [Theobroma cacao]
            gi|508724537|gb|EOY16434.1| Topbp1, putative isoform 1
            [Theobroma cacao]
          Length = 979

 Score =  872 bits (2254), Expect = 0.0
 Identities = 490/928 (52%), Positives = 622/928 (67%), Gaps = 52/928 (5%)
 Frame = -1

Query: 2687 KGCKLLGTELVISCGKENRALPKNKGFTCCLAMDGVKVLATGFDNKEKGKIEKLVTAMGG 2508
            KGC LLG + V+SC KENRALPK +GFTCCLAMDG+KVLA+GFD  EK KIEKLVTAMGG
Sbjct: 71   KGCNLLGPQCVLSCAKENRALPK-QGFTCCLAMDGLKVLASGFDMDEKVKIEKLVTAMGG 129

Query: 2507 VFQTRAALDTDFVICKNVLSGKYKWGLQTLKKPVITINWLYQCWSEHRLVPHEPCRVLPF 2328
            V  T+A+LD  FV+ KNVL+ KYKW L  LKKP++T++WLYQCW EHR+VP E  RVLPF
Sbjct: 130  VLHTKASLDVSFVVVKNVLAAKYKWALNVLKKPIVTLHWLYQCWGEHRVVPQESYRVLPF 189

Query: 2327 SGLTICFTRIAADVRKEMENLIVHNGGQYSGDLTRNCTHLISDAPEGDKYRVAQKWGHVR 2148
            SGLTIC TRI AD RKE+E LI+ NGG+YS +LT+ CTHLI DAPEGDKY+VA++WGHV 
Sbjct: 190  SGLTICVTRIPADERKEIEKLIIQNGGKYSAELTKKCTHLICDAPEGDKYKVARRWGHVH 249

Query: 2147 IVTKDWLRDSFNRKVYLPEDAYLVQGITMSANHVLKNELREKNYQDKKSTNSQSGPGPIA 1968
            IV + W   S  R+  L E++Y VQG   S+   +   L  ++ QDK   +S S    + 
Sbjct: 250  IVVRKWFDQSIARRACLNEESYPVQGGCSSSKKNVSGSLSTQHSQDKFRGSSLSATSLMI 309

Query: 1967 ADS---------------EATLXXXXXXXXXXXXXIMKGEEGIEAPPPSKIEDKEET-LD 1836
            +D                EATL             I+K E+G EAP    ++   ET LD
Sbjct: 310  SDFNLSTVPPTGVGDPDLEATLSQNIPSMVSDAQVIVK-EDGGEAPT---LQPSNETKLD 365

Query: 1835 SCVADDSQSEDSGLYLSDCRILLVGFHAAEMRKLVNKVRRGGGSRYMAFNDRLTHIVVGT 1656
             CVA+DS+SED+ LYLSDCRI LVGF A+EMRKLV  VRRGGGSRYM+ ND+LTHIVVGT
Sbjct: 366  GCVANDSESEDNDLYLSDCRISLVGFEASEMRKLVMMVRRGGGSRYMSCNDKLTHIVVGT 425

Query: 1655 PTENERRELRRYTAAGVIYVVRAVWLDDCDREKKELPVSKRHVVPDLILPKDSVCPDKAT 1476
            P+E E++E+R + A+GV+ VV++ WL+DCDR+KKE+PV +RH+  DL+LPKDSV   K  
Sbjct: 426  PSEVEKKEVRSFAASGVMQVVKSNWLEDCDRQKKEIPVQQRHIAYDLLLPKDSVQSVKGA 485

Query: 1475 KIG---TRQGHNLITPPS-------VPDHLTQCFRPSMPREQTEERKTMEASKQE----- 1341
             IG   + Q  + +   S       + D+L    + +   +++ E  T+ +SKQ      
Sbjct: 486  VIGMVSSNQSKSSVLANSGTGMSSFLGDNLDDKTKINRNGDKSLEA-TVRSSKQGVPPTV 544

Query: 1340 ------------SSMVK--KN--SSNIXXXXXXXXXXXFPLDRRAEIVEWIKQGGGEIVD 1209
                         S+V   KN  SS +           FP DRRAEIVEW+ QGGGE+VD
Sbjct: 545  NSTNNGWQKQHCGSIVLNLKNGMSSTVFKGKIFCFSNSFPEDRRAEIVEWVDQGGGEVVD 604

Query: 1208 GQSEFNVNFTVECHGLVTKAGNVSQSQTTIVSTHWIRSCLEDACMPDVGSHIIYSPVPCK 1029
               + +VNF +ECHG+++++  +  SQ T VSTHW+RSCLED C+ DVG HI+YSP+PC+
Sbjct: 605  DHVKQSVNFIIECHGVISRS--IIDSQITYVSTHWVRSCLEDGCLLDVGCHILYSPLPCQ 662

Query: 1028 IPLPGFEAFRFCVSQYEEKDRLLLRNLCFVLGAKFTEKLSKKVTHLLCKFTNGPKYEAAC 849
            IP PGF++FRFCVSQYEEKDRLLLRNLCF+LGAKF EKL+KKVTHLLCKFT+GPKYEAAC
Sbjct: 663  IPFPGFKSFRFCVSQYEEKDRLLLRNLCFILGAKFVEKLTKKVTHLLCKFTSGPKYEAAC 722

Query: 848  KWGMQTVTSEWISECIRQNAVVSAHPFRPKEMTAQDREAGLATMSQYTTQAARMISGEDV 669
            KWG+ +VT+EWI EC+ QN VVS  PF PKE+TAQDREAGL T+SQ+ TQA +M+S  D+
Sbjct: 723  KWGIYSVTAEWIYECVSQNKVVSLDPFFPKEVTAQDREAGLCTVSQFPTQAVQMMS-VDI 781

Query: 668  PSQSQGQSQFAMNSSRTFGKKSTNL---SVEAEYPSATNKKRAKVSANNDKIDLLP--LD 504
            PSQ   QSQ     ++T G K  ++     EAE  S  + KRA+    +D+  LL   + 
Sbjct: 782  PSQFMTQSQDL--RTQTLGGKIESIIGGRDEAE-QSNVHLKRARCMEEDDQNGLLASVVH 838

Query: 503  VCANVSSCTMKSIKTSEGGNIRDDGSHDVPDVAAAIEDLLEESSKIQDMALSGRTISDRS 324
            +C  V +   ++   +    I  + +  +PDVAAAIEDLLE++SKI D     R   D+S
Sbjct: 839  LCEPVLN---ENSTENNKSKIVGEAAQVLPDVAAAIEDLLEQTSKIHDQKSPERNGCDKS 895

Query: 323  IFSPDHSIITQNPATSHSAIQISTSWLSRKEKQDDGNQCDSSSVQGVNEHRTYDGFSETQ 144
            IFS D + + Q+   SHS I +S  WL+R  K+D     ++ S  G      YDGFSETQ
Sbjct: 896  IFSSDRTGLCQDHTDSHSVIGLSRHWLNRTVKKD-----ETCSYSGDGNAGLYDGFSETQ 950

Query: 143  TESQVVVYEEDLSGRQMMIDRHRTRSSM 60
            TESQVV YEEDLSGRQM+IDR RTRSSM
Sbjct: 951  TESQVVGYEEDLSGRQMLIDRVRTRSSM 978


>ref|XP_007019210.1| Topbp1, putative isoform 2 [Theobroma cacao]
            gi|508724538|gb|EOY16435.1| Topbp1, putative isoform 2
            [Theobroma cacao]
          Length = 980

 Score =  870 bits (2249), Expect = 0.0
 Identities = 491/929 (52%), Positives = 623/929 (67%), Gaps = 53/929 (5%)
 Frame = -1

Query: 2687 KGCKLLGTELVISCGKENRALPKNKGFTCCLAMDGVKVLATGFDNKEKGKIEKLVTAMGG 2508
            KGC LLG + V+SC KENRALPK +GFTCCLAMDG+KVLA+GFD  EK KIEKLVTAMGG
Sbjct: 71   KGCNLLGPQCVLSCAKENRALPK-QGFTCCLAMDGLKVLASGFDMDEKVKIEKLVTAMGG 129

Query: 2507 VFQTRAALDTDFVICKNVLSGKYKWGLQTLKKPVITINWLYQCWSEHRLVPHEPCRVLPF 2328
            V  T+A+LD  FV+ KNVL+ KYKW L  LKKP++T++WLYQCW EHR+VP E  RVLPF
Sbjct: 130  VLHTKASLDVSFVVVKNVLAAKYKWALNVLKKPIVTLHWLYQCWGEHRVVPQESYRVLPF 189

Query: 2327 SGLTICFTRIAADVRKEMENLIVHNGGQYSGDLTRNCTHLISDAPEGDKYRVAQKWGHVR 2148
            SGLTIC TRI AD RKE+E LI+ NGG+YS +LT+ CTHLI DAPEGDKY+VA++WGHV 
Sbjct: 190  SGLTICVTRIPADERKEIEKLIIQNGGKYSAELTKKCTHLICDAPEGDKYKVARRWGHVH 249

Query: 2147 IVTKDWLRDSFNRKVYLPEDAYLVQGITMSANHVLKNELREKNYQDKKSTNSQSGPGPIA 1968
            IV + W   S  R+  L E++Y VQG   S+   +   L  ++ QDK   +S S    + 
Sbjct: 250  IVVRKWFDQSIARRACLNEESYPVQGGCSSSKKNVSGSLSTQHSQDKFRGSSLSATSLMI 309

Query: 1967 ADS---------------EATLXXXXXXXXXXXXXIMKGEEGIEAPPPSKIEDKEET-LD 1836
            +D                EATL             I+K E+G EAP    ++   ET LD
Sbjct: 310  SDFNLSTVPPTGVGDPDLEATLSQNIPSMVSDAQVIVK-EDGGEAPT---LQPSNETKLD 365

Query: 1835 SCVADDSQSEDSGLYLSDCRILLVGFHAAEMRKLVNKVRRGGGSRYMAFNDRLTHIVVGT 1656
             CVA+DS+SED+ LYLSDCRI LVGF A+EMRKLV  VRRGGGSRYM+ ND+LTHIVVGT
Sbjct: 366  GCVANDSESEDNDLYLSDCRISLVGFEASEMRKLVMMVRRGGGSRYMSCNDKLTHIVVGT 425

Query: 1655 PTENERRELRRYTAAGVIYVVRAVWLDDCDREKKELPVSKRHVVPDLILPKDSVCPDKAT 1476
            P+E E++E+R + A+GV+ VV++ WL+DCDR+KKE+PV +RH+  DL+LPKDSV   K  
Sbjct: 426  PSEVEKKEVRSFAASGVMQVVKSNWLEDCDRQKKEIPVQQRHIAYDLLLPKDSVQSVKGA 485

Query: 1475 KIG---TRQGHNLITPPS-------VPDHLTQCFRPSMPREQTEERKTMEASKQE----- 1341
             IG   + Q  + +   S       + D+L    + +   +++ E  T+ +SKQ      
Sbjct: 486  VIGMVSSNQSKSSVLANSGTGMSSFLGDNLDDKTKINRNGDKSLEA-TVRSSKQGVPPTV 544

Query: 1340 ------------SSMVK--KN--SSNIXXXXXXXXXXXFPLDRRAEIVEWIKQGGGEIVD 1209
                         S+V   KN  SS +           FP DRRAEIVEW+ QGGGE+VD
Sbjct: 545  NSTNNGWQKQHCGSIVLNLKNGMSSTVFKGKIFCFSNSFPEDRRAEIVEWVDQGGGEVVD 604

Query: 1208 GQSEFNVNFTVECHGLVTKAGNVSQSQTTIVSTHWIRSCLEDACMPDVGSHIIYSPVPCK 1029
               + +VNF +ECHG+++++  +  SQ T VSTHW+RSCLED C+ DVG HI+YSP+PC+
Sbjct: 605  DHVKQSVNFIIECHGVISRS--IIDSQITYVSTHWVRSCLEDGCLLDVGCHILYSPLPCQ 662

Query: 1028 IPLPGFEAFRFCVSQYEEKDRLLLRNLCFVLGAKFTEKLSKKVTHLLCKFTNGPKYEAAC 849
            IP PGF++FRFCVSQYEEKDRLLLRNLCF+LGAKF EKL+KKVTHLLCKFT+GPKYEAAC
Sbjct: 663  IPFPGFKSFRFCVSQYEEKDRLLLRNLCFILGAKFVEKLTKKVTHLLCKFTSGPKYEAAC 722

Query: 848  KWGMQTVTSEWISECIRQNAVVSAHPFRPKEMTAQDREAGLATMSQYTTQAARMISGEDV 669
            KWG+ +VT+EWI EC+ QN VVS  PF PKE+TAQDREAGL T+SQ+ TQA +M+S  D+
Sbjct: 723  KWGIYSVTAEWIYECVSQNKVVSLDPFFPKEVTAQDREAGLCTVSQFPTQAVQMMS-VDI 781

Query: 668  PSQSQGQSQFAMNSSRTFGKKSTNL---SVEAEYPSATNKKRAKVSANNDKIDLLP--LD 504
            PSQ   QSQ     ++T G K  ++     EAE  S  + KRA+    +D+  LL   + 
Sbjct: 782  PSQFMTQSQDL--RTQTLGGKIESIIGGRDEAE-QSNVHLKRARCMEEDDQNGLLASVVH 838

Query: 503  VCANVSSCTMKSIKTSEGGNIRDDGSHDVPDVAAAIEDLLEESSKIQDMALSGRTISDRS 324
            +C  V +   ++   +    I  + +  +PDVAAAIEDLLE++SKI D     R   D+S
Sbjct: 839  LCEPVLN---ENSTENNKSKIVGEAAQVLPDVAAAIEDLLEQTSKIHDQKSPERNGCDKS 895

Query: 323  IFSPDHSIITQNPATSHSAIQISTSWLSRKEKQDDGNQCDSSSVQGVNEHRTYDGFSETQ 144
            IFS D + + Q+   SHS I +S  WL+R  K+D     ++ S  G      YDGFSETQ
Sbjct: 896  IFSSDRTGLCQDHTDSHSVIGLSRHWLNRTVKKD-----ETCSYSGDGNAGLYDGFSETQ 950

Query: 143  TESQVVV-YEEDLSGRQMMIDRHRTRSSM 60
            TESQVVV YEEDLSGRQM+IDR RTRSSM
Sbjct: 951  TESQVVVGYEEDLSGRQMLIDRVRTRSSM 979


>ref|XP_007227054.1| hypothetical protein PRUPE_ppa000738mg [Prunus persica]
            gi|462423990|gb|EMJ28253.1| hypothetical protein
            PRUPE_ppa000738mg [Prunus persica]
          Length = 1018

 Score =  855 bits (2210), Expect = 0.0
 Identities = 479/969 (49%), Positives = 612/969 (63%), Gaps = 93/969 (9%)
 Frame = -1

Query: 2687 KGCKLLGTELVISCGKENRALPKNKGFTCCLAMDGVKVLATGFDNKEKGKIEKLVTAMGG 2508
            KGC LLG + V SC  ++RALPK +GFTCCLAMDG KVLA+GF+  EK KIEKLVTAMGG
Sbjct: 69   KGCNLLGPQCVFSCANQHRALPK-QGFTCCLAMDGFKVLASGFEGDEKAKIEKLVTAMGG 127

Query: 2507 VFQTRAALDTDFVICKNVLSGKYK----------WGLQTLKKPVITINWLYQCWSEHRLV 2358
            V   +A+LD +FVI KNVL+GKYK          W L TLKKP++TINWL QCW+EHR V
Sbjct: 128  VLHAKASLDVNFVIVKNVLAGKYKAITELVLFMQWALNTLKKPIVTINWLSQCWNEHRNV 187

Query: 2357 PHEPCRVLPFSGLTICFTRIAADVRKEMENLIVHNGGQYSGDLTRN------CTHLISDA 2196
            P +  RVLPFSGL I  TRI AD RKE+E LI  NGG+YS +LT+N          +SD 
Sbjct: 188  PQDSFRVLPFSGLMISVTRIPADERKEIEKLITENGGKYSAELTKNKELESYVYFSMSDL 247

Query: 2195 -------------------PEGDKYRVAQKWGHVRIVTKDWLRDSFNRKVYLPEDAYLVQ 2073
                               PEGDKY+VAQ+WGH+RIVT+ W   S +R+  L ED+Y VQ
Sbjct: 248  HNTSRLQLNEANLEIFMFFPEGDKYKVAQRWGHIRIVTRKWFDQSISRRACLNEDSYPVQ 307

Query: 2072 GITMSANHVLKNELREKNYQDKKSTNSQSGPGPIAADS---------------EATLXXX 1938
            G ++S+N  ++     +N Q   S N QS P  + ADS               EAT+   
Sbjct: 308  GGSISSNKSVRGCFTLQNSQRSSSGNLQSVPPSVVADSNLTAAPCSGTMDSDLEATVSQN 367

Query: 1937 XXXXXXXXXXIMKGEEGIEAPPPSKIEDKEET-LDSCVADDSQSEDSGLYLSDCRILLVG 1761
                      ++K E+  +APP   +E K E  LD CVADDSQSED+ LYLS+CRI LVG
Sbjct: 368  MTTMFSHAPHVVKNEDS-KAPP---LESKSEAYLDGCVADDSQSEDNDLYLSECRISLVG 423

Query: 1760 FHAAEMRKLVNKVRRGGGSRYMAFNDRLTHIVVGTPTENERRELRRYTAAGVIYVVRAVW 1581
            F  +EMR+LVN +RRGGGSRYM+FND+LTHIVVGTP+E +++E+R + A GVI+VVR  W
Sbjct: 424  FKVSEMRRLVNMIRRGGGSRYMSFNDKLTHIVVGTPSEIQKKEVRGFAALGVIHVVRTTW 483

Query: 1580 LDDCDREKKELPVSKRHVVPDLILPKDSVCPDKATKIGTRQGHNLITPPSVPDHLTQCF- 1404
            LDDCDREKKE+PV  +H+  DL+LP+ ++    +T  GT    +L  P       T    
Sbjct: 484  LDDCDREKKEIPVLPKHIAYDLVLPEGALIGMTSTIQGTISTTHLSIPSDQLHGNTSAAT 543

Query: 1403 --------RPSMPREQTEERKTMEAS------------------------------KQES 1338
                    R   P    +  K+MEA+                              + +S
Sbjct: 544  GMGSLEKKREKKPEINMKGDKSMEAAVGPSKWSKLPVINGKSKVQLNNTIDGRLMMQYDS 603

Query: 1337 SMVKKNSSNIXXXXXXXXXXXFPLDRRAEIVEWIKQGGGEIVDGQSEFNVNFTVECHGLV 1158
            S+     S++           FP DRR +I++W+ QGGG++VDG  +  V+FT+ECHG++
Sbjct: 604  SVQNGKESSVFKGRLFCFSNSFPEDRRGDIIQWVNQGGGDVVDGDLKQKVHFTIECHGVI 663

Query: 1157 TKAGNVSQSQTTIVSTHWIRSCLEDACMPDVGSHIIYSPVPCKIPLPGFEAFRFCVSQYE 978
            T + +V+Q  TT VS+HWIRSCLED C+ DV SHI+Y+P+PC+IPLPGFE FRFCVSQYE
Sbjct: 664  TSSVDVAQ--TTYVSSHWIRSCLEDGCLLDVSSHILYAPLPCRIPLPGFENFRFCVSQYE 721

Query: 977  EKDRLLLRNLCFVLGAKFTEKLSKKVTHLLCKFTNGPKYEAACKWGMQTVTSEWISECIR 798
            EKDRLLLRNLCFVLGAKF EKL+KKVTHLLCKFTNGPKY+AAC  G+  +T+EW+ EC++
Sbjct: 722  EKDRLLLRNLCFVLGAKFGEKLTKKVTHLLCKFTNGPKYQAACIKGIHPITAEWVYECVK 781

Query: 797  QNAVVSAHPFRPKEMTAQDREAGLATMSQYTTQAARMIS---GEDVPSQSQGQSQFAMNS 627
            +N VV+   F PK++TA+DREAGL TMSQY TQA +MIS     + PSQSQ       +S
Sbjct: 782  KNKVVALDQFYPKKVTAEDREAGLCTMSQYPTQAVQMISAGNSSECPSQSQ---DLRTSS 838

Query: 626  SRTFGKKSTNLSVEAEYPSATNKKRAKVSANNDKIDLLPLDVCANVSSCTMKSIKTSEGG 447
                G ++ +L  EA  PS  NKK A+VS ++ +  LL   V   + +CT    K    G
Sbjct: 839  GENIGSRNDSLREEASEPSFCNKK-ARVSEDDGEKGLLSSGVHLRIPACTTGDRKVKSSG 897

Query: 446  NIRDDGSHDVPDVAAAIEDLLEESSKIQDMALSGRTISDRSIFSPDHSIITQNPATSHSA 267
             +    S  VPDVA+AIEDLLE++SKI D    GR++ D SIFSP+ S + Q+ + +HS 
Sbjct: 898  EV----SQVVPDVASAIEDLLEQTSKIHDQKSPGRSLCDSSIFSPECSALRQDHSDAHSV 953

Query: 266  IQISTSWLSRKEKQDDGNQCDSSSVQGVNEHRTYDGFSETQTESQVVVYEEDLSGRQMMI 87
            I +S  WL+R  K+DD +        G+     YDGFSETQTESQVV YEEDLSGRQM+I
Sbjct: 954  IGLSRHWLNRAGKKDDIHYPSEEQKAGL-----YDGFSETQTESQVVGYEEDLSGRQMLI 1008

Query: 86   DRHRTRSSM 60
            DR RTRSS+
Sbjct: 1009 DRVRTRSSL 1017


>ref|XP_012464226.1| PREDICTED: DNA topoisomerase 2-binding protein 1-A isoform X1
            [Gossypium raimondii]
          Length = 985

 Score =  840 bits (2171), Expect = 0.0
 Identities = 474/932 (50%), Positives = 601/932 (64%), Gaps = 55/932 (5%)
 Frame = -1

Query: 2687 KGCKLLGTELVISCGKENRALPKNKGFTCCLAMDGVKVLATGFDNKEKGKIEKLVTAMGG 2508
            KGC L+G + VISC  ENRALPK +GF+CCLAMDG+KVLA+GFD  EK KIEKLV AMGG
Sbjct: 72   KGCNLIGPQCVISCANENRALPK-QGFSCCLAMDGLKVLASGFDMDEKVKIEKLVIAMGG 130

Query: 2507 VFQTRAALDTDFVICKNVLSGKYKWGLQTLKKPVITINWLYQCWSEHRLVPHEPCRVLPF 2328
            V  T+A+LD  FVI KNVL+ KYKW L  LKKP++TI WLYQCWSEHR+VP E  RVLPF
Sbjct: 131  VLHTKASLDVSFVIVKNVLAAKYKWALNVLKKPIVTIQWLYQCWSEHRVVPQESYRVLPF 190

Query: 2327 SGLTICFTRIAADVRKEMENLIVHNGGQYSGDLTRNCTHLISDAPEGDKYRVAQKWGHVR 2148
            +GLTI  T I AD RKE+E LI+ NGG+YS +LT+ CTHLI D PEGDKY+VA++WGHV 
Sbjct: 191  TGLTISVTGIRADERKEIEKLIIQNGGKYSAELTKKCTHLICDVPEGDKYKVARRWGHVH 250

Query: 2147 IVTKDWLRDSFNRKVYLPEDAYLVQGITMSANHVLKNELREKNYQDKKSTNSQSGPGPIA 1968
            I+ + W      R+  L E++Y VQG + S+   +   L  ++ QDK   +S S    + 
Sbjct: 251  IIVRKWFDQCIARRACLNEESYPVQGGSASSKKSVSGSLSAQHSQDKFRASSVSATSLVV 310

Query: 1967 A---------------DSEATLXXXXXXXXXXXXXIMKGEEGIEAPPPSKIEDKEET-LD 1836
                            D EA               I + E+G EAP    ++   ET LD
Sbjct: 311  PEFNMSTVPSTGLGDPDLEAAHSQNTPSVLSDAQAIFE-EDGGEAP---NLQPSTETKLD 366

Query: 1835 SCVADDSQSEDSGLYLSDCRILLVGFHAAEMRKLVNKVRRGGGSRYMAFNDRLTHIVVGT 1656
             CVA+DSQSED+ LYLSDC+I LVGF A+EMRKLV  VRRGG SRYM+ N++LTHIVVG 
Sbjct: 367  GCVANDSQSEDNDLYLSDCKISLVGFEASEMRKLVTMVRRGGASRYMSCNEKLTHIVVGA 426

Query: 1655 PTENERRELRRYTAAGVIYVVRAVWLDDCDREKKELPVSKRHVVPDLILPKDS------- 1497
            P+E E++E+R   A+GVI+VV+  WL+DCDR+KKE+PV +RHV   L+LPKDS       
Sbjct: 427  PSELEKKEVRSIAASGVIHVVKTSWLEDCDRQKKEIPVHQRHVAYGLLLPKDSAHSVRGA 486

Query: 1496 -------------VCPDKATKIGTRQGHNLITPPSVPDHLTQCFRPSMPREQTEERKTME 1356
                         V  +  T + +  G +L   P +  +   C + ++   +     T+ 
Sbjct: 487  VTGIINSNQSKSSVPTNSGTGMPSSFGKSLDDKPKINMNGGSCLKATVGSSKQGLLPTIN 546

Query: 1355 AS-----KQESSMVKKN-----SSNIXXXXXXXXXXXFPLDRRAEIVEWIKQGGGEIVDG 1206
            ++     KQ+   V +N     SS +           FP DRRAEIVEW+ QGGG++V+ 
Sbjct: 547  STSNFWQKQQYDSVVQNPKNGISSAVFKGKTFCFSVSFPEDRRAEIVEWVDQGGGQVVED 606

Query: 1205 QSEFNVNFTVECHGLVTKAGNVSQSQTTIVSTHWIRSCLEDACMPDVGSHIIYSPVPCKI 1026
            Q + NVNF +ECHG++     ++ SQ T VSTHW+RSCLED C+ DVG HI+YSP+PC+I
Sbjct: 607  QVKKNVNFIIECHGVIPSC--ITDSQITYVSTHWVRSCLEDGCLLDVGRHILYSPLPCQI 664

Query: 1025 PLPGFEAFRFCVSQYEEKDRLLLRNLCFVLGAKFTEKLSKKVTHLLCKFTNGPKYEAACK 846
            P PGF+ FRFCVSQYEEKDRLLLRNLCF+LGAKF EKL+KKVTHLLCKFT+GPKYEAACK
Sbjct: 665  PFPGFKNFRFCVSQYEEKDRLLLRNLCFILGAKFVEKLTKKVTHLLCKFTSGPKYEAACK 724

Query: 845  WGMQTVTSEWISECIRQNAVVSAHPFRPKEMTAQDREAGLATMSQYTTQAARMISGEDVP 666
            WG+Q+VTSEWI EC+RQN VVS  PF PKE+TAQD+EAGL T+SQ+ TQAA+MI+  DVP
Sbjct: 725  WGIQSVTSEWIYECVRQNKVVSLDPFCPKEVTAQDQEAGLCTVSQFPTQAAKMIA-VDVP 783

Query: 665  SQSQGQSQ------FAMNSSRTFGKKSTNLSVEAEYPSATNKKRAKVSANNDKIDLLPLD 504
            SQ   Q Q        +      G ++     EAE  S  + KRA+   ++D+ DLL   
Sbjct: 784  SQFTSQPQGLRTQDLGVKMGSITGDRNDGSRDEAE-QSNDHFKRARHLEDDDQNDLL--- 839

Query: 503  VCANVSSCTMKSIKTSEGGN-IRDDG--SHDVPDVAAAIEDLLEESSKIQDMALSGRTIS 333
              + V  C     + S G N +++ G  +  +PDV   I DLLE++SKI D     R   
Sbjct: 840  -VSRVHLCEPFLNENSTGNNKLKNAGEAAQVLPDVDTVI-DLLEQTSKIHDQKSPERNGC 897

Query: 332  DRSIFSPDHSIITQNPATSHSAIQISTSWLSRKEKQDDGNQCDSSSVQGVNEHRTYDGFS 153
            DRSIF  D + + Q+    HS I +S  WL+R  ++D+     SS  + VN    Y GFS
Sbjct: 898  DRSIFLSDCTGLRQDHTDPHSVIGLSRHWLNRNVRKDE----ISSHSRDVNAGSLYGGFS 953

Query: 152  ETQTESQVVVYEEDLSGRQMMIDRHRTRSSMT 57
            ETQTESQVV YEEDLSGRQM+IDR RTRSSMT
Sbjct: 954  ETQTESQVVGYEEDLSGRQMLIDRVRTRSSMT 985


>ref|XP_007019212.1| Topbp1, putative isoform 4 [Theobroma cacao]
            gi|508724540|gb|EOY16437.1| Topbp1, putative isoform 4
            [Theobroma cacao]
          Length = 971

 Score =  836 bits (2159), Expect = 0.0
 Identities = 470/905 (51%), Positives = 601/905 (66%), Gaps = 52/905 (5%)
 Frame = -1

Query: 2687 KGCKLLGTELVISCGKENRALPKNKGFTCCLAMDGVKVLATGFDNKEKGKIEKLVTAMGG 2508
            KGC LLG + V+SC KENRALPK +GFTCCLAMDG+KVLA+GFD  EK KIEKLVTAMGG
Sbjct: 71   KGCNLLGPQCVLSCAKENRALPK-QGFTCCLAMDGLKVLASGFDMDEKVKIEKLVTAMGG 129

Query: 2507 VFQTRAALDTDFVICKNVLSGKYKWGLQTLKKPVITINWLYQCWSEHRLVPHEPCRVLPF 2328
            V  T+A+LD  FV+ KNVL+ KYKW L  LKKP++T++WLYQCW EHR+VP E  RVLPF
Sbjct: 130  VLHTKASLDVSFVVVKNVLAAKYKWALNVLKKPIVTLHWLYQCWGEHRVVPQESYRVLPF 189

Query: 2327 SGLTICFTRIAADVRKEMENLIVHNGGQYSGDLTRNCTHLISDAPEGDKYRVAQKWGHVR 2148
            SGLTIC TRI AD RKE+E LI+ NGG+YS +LT+ CTHLI DAPEGDKY+VA++WGHV 
Sbjct: 190  SGLTICVTRIPADERKEIEKLIIQNGGKYSAELTKKCTHLICDAPEGDKYKVARRWGHVH 249

Query: 2147 IVTKDWLRDSFNRKVYLPEDAYLVQGITMSANHVLKNELREKNYQDKKSTNSQSGPGPIA 1968
            IV + W   S  R+  L E++Y VQG   S+   +   L  ++ QDK   +S S    + 
Sbjct: 250  IVVRKWFDQSIARRACLNEESYPVQGGCSSSKKNVSGSLSTQHSQDKFRGSSLSATSLMI 309

Query: 1967 ADS---------------EATLXXXXXXXXXXXXXIMKGEEGIEAPPPSKIEDKEET-LD 1836
            +D                EATL             I+K E+G EAP    ++   ET LD
Sbjct: 310  SDFNLSTVPPTGVGDPDLEATLSQNIPSMVSDAQVIVK-EDGGEAPT---LQPSNETKLD 365

Query: 1835 SCVADDSQSEDSGLYLSDCRILLVGFHAAEMRKLVNKVRRGGGSRYMAFNDRLTHIVVGT 1656
             CVA+DS+SED+ LYLSDCRI LVGF A+EMRKLV  VRRGGGSRYM+ ND+LTHIVVGT
Sbjct: 366  GCVANDSESEDNDLYLSDCRISLVGFEASEMRKLVMMVRRGGGSRYMSCNDKLTHIVVGT 425

Query: 1655 PTENERRELRRYTAAGVIYVVRAVWLDDCDREKKELPVSKRHVVPDLILPKDSVCPDKAT 1476
            P+E E++E+R + A+GV+ VV++ WL+DCDR+KKE+PV +RH+  DL+LPKDSV   K  
Sbjct: 426  PSEVEKKEVRSFAASGVMQVVKSNWLEDCDRQKKEIPVQQRHIAYDLLLPKDSVQSVKGA 485

Query: 1475 KIG---TRQGHNLITPPS-------VPDHLTQCFRPSMPREQTEERKTMEASKQE----- 1341
             IG   + Q  + +   S       + D+L    + +   +++ E  T+ +SKQ      
Sbjct: 486  VIGMVSSNQSKSSVLANSGTGMSSFLGDNLDDKTKINRNGDKSLEA-TVRSSKQGVPPTV 544

Query: 1340 ------------SSMVK--KN--SSNIXXXXXXXXXXXFPLDRRAEIVEWIKQGGGEIVD 1209
                         S+V   KN  SS +           FP DRRAEIVEW+ QGGGE+VD
Sbjct: 545  NSTNNGWQKQHCGSIVLNLKNGMSSTVFKGKIFCFSNSFPEDRRAEIVEWVDQGGGEVVD 604

Query: 1208 GQSEFNVNFTVECHGLVTKAGNVSQSQTTIVSTHWIRSCLEDACMPDVGSHIIYSPVPCK 1029
               + +VNF +ECHG+++++  +  SQ T VSTHW+RSCLED C+ DVG HI+YSP+PC+
Sbjct: 605  DHVKQSVNFIIECHGVISRS--IIDSQITYVSTHWVRSCLEDGCLLDVGCHILYSPLPCQ 662

Query: 1028 IPLPGFEAFRFCVSQYEEKDRLLLRNLCFVLGAKFTEKLSKKVTHLLCKFTNGPKYEAAC 849
            IP PGF++FRFCVSQYEEKDRLLLRNLCF+LGAKF EKL+KKVTHLLCKFT+GPKYEAAC
Sbjct: 663  IPFPGFKSFRFCVSQYEEKDRLLLRNLCFILGAKFVEKLTKKVTHLLCKFTSGPKYEAAC 722

Query: 848  KWGMQTVTSEWISECIRQNAVVSAHPFRPKEMTAQDREAGLATMSQYTTQAARMISGEDV 669
            KWG+ +VT+EWI EC+ QN VVS  PF PKE+TAQDREAGL T+SQ+ TQA +M+S  D+
Sbjct: 723  KWGIYSVTAEWIYECVSQNKVVSLDPFFPKEVTAQDREAGLCTVSQFPTQAVQMMS-VDI 781

Query: 668  PSQSQGQSQFAMNSSRTFGKKSTNL---SVEAEYPSATNKKRAKVSANNDKIDLLP--LD 504
            PSQ   QSQ     ++T G K  ++     EAE  S  + KRA+    +D+  LL   + 
Sbjct: 782  PSQFMTQSQDL--RTQTLGGKIESIIGGRDEAE-QSNVHLKRARCMEEDDQNGLLASVVH 838

Query: 503  VCANVSSCTMKSIKTSEGGNIRDDGSHDVPDVAAAIEDLLEESSKIQDMALSGRTISDRS 324
            +C  V +   ++   +    I  + +  +PDVAAAIEDLLE++SKI D     R   D+S
Sbjct: 839  LCEPVLN---ENSTENNKSKIVGEAAQVLPDVAAAIEDLLEQTSKIHDQKSPERNGCDKS 895

Query: 323  IFSPDHSIITQNPATSHSAIQISTSWLSRKEKQDDGNQCDSSSVQGVNEHRTYDGFSETQ 144
            IFS D + + Q+   SHS I +S  WL+R  K+D     ++ S  G      YDGFSETQ
Sbjct: 896  IFSSDRTGLCQDHTDSHSVIGLSRHWLNRTVKKD-----ETCSYSGDGNAGLYDGFSETQ 950

Query: 143  TESQV 129
            TESQV
Sbjct: 951  TESQV 955


>gb|KJB80623.1| hypothetical protein B456_013G107700 [Gossypium raimondii]
          Length = 977

 Score =  819 bits (2116), Expect = 0.0
 Identities = 468/932 (50%), Positives = 595/932 (63%), Gaps = 55/932 (5%)
 Frame = -1

Query: 2687 KGCKLLGTELVISCGKENRALPKNKGFTCCLAMDGVKVLATGFDNKEKGKIEKLVTAMGG 2508
            KGC L+G + VISC  ENRALPK +GF+CCLAMDG+KVLA+GFD  EK KIEKLV AMGG
Sbjct: 71   KGCNLIGPQCVISCANENRALPK-QGFSCCLAMDGLKVLASGFDMDEKVKIEKLVIAMGG 129

Query: 2507 VFQTRAALDTDFVICKNVLSGKYKWGLQTLKKPVITINWLYQCWSEHRLVPHEPCRVLPF 2328
            V  T+A+LD  FVI KNVL+ KYKW L  LKKP++TI WLYQCWSEHR+VP E  RVLPF
Sbjct: 130  VLHTKASLDVSFVIVKNVLAAKYKWALNVLKKPIVTIQWLYQCWSEHRVVPQESYRVLPF 189

Query: 2327 SGLTICFTRIAADVRKEMENLIVHNGGQYSGDLTRNCTHLISDAPEGDKYRVAQKWGHVR 2148
            +GLTI  T I AD RKE+E LI+ NGG+YS +LT+         PEGDKY+VA++WGHV 
Sbjct: 190  TGLTISVTGIRADERKEIEKLIIQNGGKYSAELTKKF-------PEGDKYKVARRWGHVH 242

Query: 2147 IVTKDWLRDSFNRKVYLPEDAYLVQGITMSANHVLKNELREKNYQDKKSTNSQSGPGPIA 1968
            I+ + W      R+  L E++Y VQG + S+   +   L  ++ QDK   +S S    + 
Sbjct: 243  IIVRKWFDQCIARRACLNEESYPVQGGSASSKKSVSGSLSAQHSQDKFRASSVSATSLVV 302

Query: 1967 A---------------DSEATLXXXXXXXXXXXXXIMKGEEGIEAPPPSKIEDKEET-LD 1836
                            D EA               I + E+G EAP    ++   ET LD
Sbjct: 303  PEFNMSTVPSTGLGDPDLEAAHSQNTPSVLSDAQAIFE-EDGGEAP---NLQPSTETKLD 358

Query: 1835 SCVADDSQSEDSGLYLSDCRILLVGFHAAEMRKLVNKVRRGGGSRYMAFNDRLTHIVVGT 1656
             CVA+DSQSED+ LYLSDC+I LVGF A+EMRKLV  VRRGG SRYM+ N++LTHIVVG 
Sbjct: 359  GCVANDSQSEDNDLYLSDCKISLVGFEASEMRKLVTMVRRGGASRYMSCNEKLTHIVVGA 418

Query: 1655 PTENERRELRRYTAAGVIYVVRAVWLDDCDREKKELPVSKRHVVPDLILPKDS------- 1497
            P+E E++E+R   A+GVI+VV+  WL+DCDR+KKE+PV +RHV   L+LPKDS       
Sbjct: 419  PSELEKKEVRSIAASGVIHVVKTSWLEDCDRQKKEIPVHQRHVAYGLLLPKDSAHSVRGA 478

Query: 1496 -------------VCPDKATKIGTRQGHNLITPPSVPDHLTQCFRPSMPREQTEERKTME 1356
                         V  +  T + +  G +L   P +  +   C + ++   +     T+ 
Sbjct: 479  VTGIINSNQSKSSVPTNSGTGMPSSFGKSLDDKPKINMNGGSCLKATVGSSKQGLLPTIN 538

Query: 1355 AS-----KQESSMVKKN-----SSNIXXXXXXXXXXXFPLDRRAEIVEWIKQGGGEIVDG 1206
            ++     KQ+   V +N     SS +           FP DRRAEIVEW+ QGGG++V+ 
Sbjct: 539  STSNFWQKQQYDSVVQNPKNGISSAVFKGKTFCFSVSFPEDRRAEIVEWVDQGGGQVVED 598

Query: 1205 QSEFNVNFTVECHGLVTKAGNVSQSQTTIVSTHWIRSCLEDACMPDVGSHIIYSPVPCKI 1026
            Q + NVNF +ECHG++     ++ SQ T VSTHW+RSCLED C+ DVG HI+YSP+PC+I
Sbjct: 599  QVKKNVNFIIECHGVIPSC--ITDSQITYVSTHWVRSCLEDGCLLDVGRHILYSPLPCQI 656

Query: 1025 PLPGFEAFRFCVSQYEEKDRLLLRNLCFVLGAKFTEKLSKKVTHLLCKFTNGPKYEAACK 846
            P PGF+ FRFCVSQYEEKDRLLLRNLCF+LGAKF EKL+KKVTHLLCKFT+GPKYEAACK
Sbjct: 657  PFPGFKNFRFCVSQYEEKDRLLLRNLCFILGAKFVEKLTKKVTHLLCKFTSGPKYEAACK 716

Query: 845  WGMQTVTSEWISECIRQNAVVSAHPFRPKEMTAQDREAGLATMSQYTTQAARMISGEDVP 666
            WG+Q+VTSEWI EC+RQN VVS  PF PKE+TAQD+EAGL T+SQ+ TQAA+MI+  DVP
Sbjct: 717  WGIQSVTSEWIYECVRQNKVVSLDPFCPKEVTAQDQEAGLCTVSQFPTQAAKMIA-VDVP 775

Query: 665  SQSQGQSQ------FAMNSSRTFGKKSTNLSVEAEYPSATNKKRAKVSANNDKIDLLPLD 504
            SQ   Q Q        +      G ++     EAE  S  + KRA+   ++D+ DLL   
Sbjct: 776  SQFTSQPQGLRTQDLGVKMGSITGDRNDGSRDEAE-QSNDHFKRARHLEDDDQNDLL--- 831

Query: 503  VCANVSSCTMKSIKTSEGGN-IRDDG--SHDVPDVAAAIEDLLEESSKIQDMALSGRTIS 333
              + V  C     + S G N +++ G  +  +PDV   I DLLE++SKI D     R   
Sbjct: 832  -VSRVHLCEPFLNENSTGNNKLKNAGEAAQVLPDVDTVI-DLLEQTSKIHDQKSPERNGC 889

Query: 332  DRSIFSPDHSIITQNPATSHSAIQISTSWLSRKEKQDDGNQCDSSSVQGVNEHRTYDGFS 153
            DRSIF  D + + Q+    HS I +S  WL+R  ++D+     SS  + VN    Y GFS
Sbjct: 890  DRSIFLSDCTGLRQDHTDPHSVIGLSRHWLNRNVRKDE----ISSHSRDVNAGSLYGGFS 945

Query: 152  ETQTESQVVVYEEDLSGRQMMIDRHRTRSSMT 57
            ETQTESQVV YEEDLSGRQM+IDR RTRSSMT
Sbjct: 946  ETQTESQVVGYEEDLSGRQMLIDRVRTRSSMT 977


>ref|XP_010320793.1| PREDICTED: DNA topoisomerase 2-binding protein 1 isoform X1 [Solanum
            lycopersicum]
          Length = 991

 Score =  818 bits (2114), Expect = 0.0
 Identities = 447/934 (47%), Positives = 585/934 (62%), Gaps = 59/934 (6%)
 Frame = -1

Query: 2687 KGCKLLGTELVISCGKENRALPKNKGFTCCLAMDGVKVLATGFDNKEKGKIEKLVTAMGG 2508
            KGC L+G + V+SC KE R LP+ +GFTCCLAMDGVK+LA+GF+  EK +I KLV AMGG
Sbjct: 69   KGCNLIGPQCVLSCAKEQRPLPQ-QGFTCCLAMDGVKILASGFEMDEKVEIGKLVIAMGG 127

Query: 2507 VFQTRAALDTDFVICKNVLSGKYKWGLQTLKKPVITINWLYQCWSEHRLVPHEPCRVLPF 2328
            V QT+A+LD  FVI KNVL+ KYKW    LKKP++TINWL+QCW EHRLVP E  ++LPF
Sbjct: 128  VLQTKASLDVSFVIVKNVLAAKYKWAYNILKKPIVTINWLHQCWKEHRLVPQESFKILPF 187

Query: 2327 SGLTICFTRIAADVRKEMENLIVHNGGQYSGDLTRNCTHLISDAPEGDKYRVAQKWGHVR 2148
            SGLTI  TRI AD R++ME +I+ NGG+YS +LTR C+HLI D PEGDK++VA++WG + 
Sbjct: 188  SGLTISVTRIPADERRDMEKIILQNGGKYSPELTRKCSHLICDVPEGDKFKVAKRWGCIH 247

Query: 2147 IVTKDWLRDSFNRKVYLPEDAYLVQG-------ITMSANHVLKNELREKNYQDKKSTNSQ 1989
             VTK W   S  R+  L E++Y VQ        + M+  H L+  +R  N Q   S  + 
Sbjct: 248  TVTKRWFEQSVARRACLNEESYPVQSGSNTLSIVRMTNQHSLEKGIR--NLQGLSSLATA 305

Query: 1988 SGPGPI------AADSEATLXXXXXXXXXXXXXIMKGEEGIEAPPP-------------- 1869
            S   P+       +D EATL             + K EE   A  P              
Sbjct: 306  SNAEPVFCSRVADSDLEATLSQNMSGTSSYVPVVTKEEENSPAEYPKSDYSAPVSTKGEK 365

Query: 1868 SKIEDKEETLDSCVADDSQSEDSGLYLSDCRILLVGFHAAEMRKLVNKVRRGGGSRYMAF 1689
            S    + +  D  VADDS+++D+ LYL+DCRIL+VGF+A+EMRKLVN VR+GGGSRYM+F
Sbjct: 366  SGASTEHDGCDGVVADDSETDDNDLYLADCRILIVGFNASEMRKLVNLVRKGGGSRYMSF 425

Query: 1688 NDRLTHIVVGTPTENERRELRRYTAAGVIYVVRAVWLDDCDREKKELPVSKRHVVPDLIL 1509
             ++LTHI+ G P+ENE +ELR   A GVI+VV++ WL+DCDRE KE+PV ++H+  DL+L
Sbjct: 426  GEKLTHIIAGNPSENEIKELRNLAALGVIHVVKSGWLEDCDRENKEVPVLRKHIAYDLLL 485

Query: 1508 PKDSVCPDKATKIGT---RQGHNLITPPSVPDHL-----TQCFRPSMPREQTEERKTMEA 1353
            PKD +       I T   RQG + + P S  +H      + C  PS   ++ E    +  
Sbjct: 486  PKDPIHCSNGAAITTTIKRQGKSYVHPMSSDEHAWRSRDSGCAMPSYESKEVENMNDVRT 545

Query: 1352 S---------------KQESSMVKKNS--------SNIXXXXXXXXXXXFPLDRRAEIVE 1242
            S               K+E  +  ++S        S++           FP DRRAEIVE
Sbjct: 546  SLGENGVQHQPYASNGKEEFKIPNESSCAVNGRKPSSVFEGRRFCFSASFPADRRAEIVE 605

Query: 1241 WIKQGGGEIVDGQSEFNVNFTVECHGLVTKAGNVSQSQTTIVSTHWIRSCLEDACMPDVG 1062
            W+ QGGG +V  Q+E N++FT+ECHG++        + TT VS+HWI+SCLED C+ DVG
Sbjct: 606  WVNQGGGVVVKDQNETNLHFTIECHGML--RSEKDGAATTFVSSHWIKSCLEDGCLLDVG 663

Query: 1061 SHIIYSPVPCKIPLPGFEAFRFCVSQYEEKDRLLLRNLCFVLGAKFTEKLSKKVTHLLCK 882
             HI+YSP+PC++P P F++FR CVSQY+EK+R LLRNLCF +GAKF EKL+KKVTHLLCK
Sbjct: 664  DHILYSPLPCRVPFPAFKSFRLCVSQYDEKERQLLRNLCFTIGAKFVEKLTKKVTHLLCK 723

Query: 881  FTNGPKYEAACKWGMQTVTSEWISECIRQNAVVSAHPFRPKEMTAQDREAGLATMSQYTT 702
            FT+GPKYEAACKWG+Q VT EWI ECI+QN +VSA PF PKE+T++DREAG  T+SQ+ T
Sbjct: 724  FTDGPKYEAACKWGIQPVTCEWIYECIKQNKIVSADPFYPKEVTSEDREAGACTVSQFPT 783

Query: 701  QAARMISGEDVPSQSQGQSQFAMN-SSRTFGKKSTNLSVEAEYPSATNKKRAKVSANNDK 525
            QA  MISG D  SQ Q Q Q  +N  +  F  ++T    E +YPS  NKK         K
Sbjct: 784  QAFGMISG-DTTSQPQTQPQELVNVRTEAFAGRNT-AKEEKKYPSRWNKKARLFVVEEPK 841

Query: 524  IDLLPLDVCANVSSCTMKSIKTSEGGNIRDDGSHDVPDVAAAIEDLLEESSKIQDMALSG 345
              L      +N         K   G    ++GS  VPDVAAAIEDLLE++SKI D     
Sbjct: 842  CSLSCSPKESNAFCGASPPEKNLTGST--NEGSSAVPDVAAAIEDLLEQTSKIHDQKSPS 899

Query: 344  RTISDRSIFSPDHSIITQNPATSHSAIQISTSWLSRKEKQDDGNQCDSSSVQGVNEHRTY 165
            R+  D+ +F+   + + Q    +H+ + +S  W +R EK+D+ +     +   V     Y
Sbjct: 900  RSECDKELFTSGCNNLAQGHGDNHATLGLSNHWTNRFEKEDETHTHSGDATANV-----Y 954

Query: 164  DGFSETQTESQVVVYEEDLSGRQMMIDRHRTRSS 63
            D FSETQT+SQVV Y EDLSGRQM+IDR RTRSS
Sbjct: 955  DHFSETQTDSQVVGYAEDLSGRQMIIDRVRTRSS 988


>ref|XP_007019211.1| Topbp1, putative isoform 3 [Theobroma cacao]
            gi|508724539|gb|EOY16436.1| Topbp1, putative isoform 3
            [Theobroma cacao]
          Length = 929

 Score =  811 bits (2096), Expect = 0.0
 Identities = 453/869 (52%), Positives = 581/869 (66%), Gaps = 52/869 (5%)
 Frame = -1

Query: 2687 KGCKLLGTELVISCGKENRALPKNKGFTCCLAMDGVKVLATGFDNKEKGKIEKLVTAMGG 2508
            KGC LLG + V+SC KENRALPK +GFTCCLAMDG+KVLA+GFD  EK KIEKLVTAMGG
Sbjct: 71   KGCNLLGPQCVLSCAKENRALPK-QGFTCCLAMDGLKVLASGFDMDEKVKIEKLVTAMGG 129

Query: 2507 VFQTRAALDTDFVICKNVLSGKYKWGLQTLKKPVITINWLYQCWSEHRLVPHEPCRVLPF 2328
            V  T+A+LD  FV+ KNVL+ KYKW L  LKKP++T++WLYQCW EHR+VP E  RVLPF
Sbjct: 130  VLHTKASLDVSFVVVKNVLAAKYKWALNVLKKPIVTLHWLYQCWGEHRVVPQESYRVLPF 189

Query: 2327 SGLTICFTRIAADVRKEMENLIVHNGGQYSGDLTRNCTHLISDAPEGDKYRVAQKWGHVR 2148
            SGLTIC TRI AD RKE+E LI+ NGG+YS +LT+ CTHLI DAPEGDKY+VA++WGHV 
Sbjct: 190  SGLTICVTRIPADERKEIEKLIIQNGGKYSAELTKKCTHLICDAPEGDKYKVARRWGHVH 249

Query: 2147 IVTKDWLRDSFNRKVYLPEDAYLVQGITMSANHVLKNELREKNYQDKKSTNSQSGPGPIA 1968
            IV + W   S  R+  L E++Y VQG   S+   +   L  ++ QDK   +S S    + 
Sbjct: 250  IVVRKWFDQSIARRACLNEESYPVQGGCSSSKKNVSGSLSTQHSQDKFRGSSLSATSLMI 309

Query: 1967 ADS---------------EATLXXXXXXXXXXXXXIMKGEEGIEAPPPSKIEDKEET-LD 1836
            +D                EATL             I+K E+G EAP    ++   ET LD
Sbjct: 310  SDFNLSTVPPTGVGDPDLEATLSQNIPSMVSDAQVIVK-EDGGEAPT---LQPSNETKLD 365

Query: 1835 SCVADDSQSEDSGLYLSDCRILLVGFHAAEMRKLVNKVRRGGGSRYMAFNDRLTHIVVGT 1656
             CVA+DS+SED+ LYLSDCRI LVGF A+EMRKLV  VRRGGGSRYM+ ND+LTHIVVGT
Sbjct: 366  GCVANDSESEDNDLYLSDCRISLVGFEASEMRKLVMMVRRGGGSRYMSCNDKLTHIVVGT 425

Query: 1655 PTENERRELRRYTAAGVIYVVRAVWLDDCDREKKELPVSKRHVVPDLILPKDSVCPDKAT 1476
            P+E E++E+R + A+GV+ VV++ WL+DCDR+KKE+PV +RH+  DL+LPKDSV   K  
Sbjct: 426  PSEVEKKEVRSFAASGVMQVVKSNWLEDCDRQKKEIPVQQRHIAYDLLLPKDSVQSVKGA 485

Query: 1475 KIG---TRQGHNLITPPS-------VPDHLTQCFRPSMPREQTEERKTMEASKQE----- 1341
             IG   + Q  + +   S       + D+L    + +   +++ E  T+ +SKQ      
Sbjct: 486  VIGMVSSNQSKSSVLANSGTGMSSFLGDNLDDKTKINRNGDKSLEA-TVRSSKQGVPPTV 544

Query: 1340 ------------SSMVK--KN--SSNIXXXXXXXXXXXFPLDRRAEIVEWIKQGGGEIVD 1209
                         S+V   KN  SS +           FP DRRAEIVEW+ QGGGE+VD
Sbjct: 545  NSTNNGWQKQHCGSIVLNLKNGMSSTVFKGKIFCFSNSFPEDRRAEIVEWVDQGGGEVVD 604

Query: 1208 GQSEFNVNFTVECHGLVTKAGNVSQSQTTIVSTHWIRSCLEDACMPDVGSHIIYSPVPCK 1029
               + +VNF +ECHG+++++  +  SQ T VSTHW+RSCLED C+ DVG HI+YSP+PC+
Sbjct: 605  DHVKQSVNFIIECHGVISRS--IIDSQITYVSTHWVRSCLEDGCLLDVGCHILYSPLPCQ 662

Query: 1028 IPLPGFEAFRFCVSQYEEKDRLLLRNLCFVLGAKFTEKLSKKVTHLLCKFTNGPKYEAAC 849
            IP PGF++FRFCVSQYEEKDRLLLRNLCF+LGAKF EKL+KKVTHLLCKFT+GPKYEAAC
Sbjct: 663  IPFPGFKSFRFCVSQYEEKDRLLLRNLCFILGAKFVEKLTKKVTHLLCKFTSGPKYEAAC 722

Query: 848  KWGMQTVTSEWISECIRQNAVVSAHPFRPKEMTAQDREAGLATMSQYTTQAARMISGEDV 669
            KWG+ +VT+EWI EC+ QN VVS  PF PKE+TAQDREAGL T+SQ+ TQA +M+S  D+
Sbjct: 723  KWGIYSVTAEWIYECVSQNKVVSLDPFFPKEVTAQDREAGLCTVSQFPTQAVQMMS-VDI 781

Query: 668  PSQSQGQSQFAMNSSRTFGKKSTNL---SVEAEYPSATNKKRAKVSANNDKIDLLP--LD 504
            PSQ   QSQ     ++T G K  ++     EAE  S  + KRA+    +D+  LL   + 
Sbjct: 782  PSQFMTQSQDL--RTQTLGGKIESIIGGRDEAE-QSNVHLKRARCMEEDDQNGLLASVVH 838

Query: 503  VCANVSSCTMKSIKTSEGGNIRDDGSHDVPDVAAAIEDLLEESSKIQDMALSGRTISDRS 324
            +C  V +   ++   +    I  + +  +PDVAAAIEDLLE++SKI D     R   D+S
Sbjct: 839  LCEPVLN---ENSTENNKSKIVGEAAQVLPDVAAAIEDLLEQTSKIHDQKSPERNGCDKS 895

Query: 323  IFSPDHSIITQNPATSHSAIQISTSWLSR 237
            IFS D + + Q+   SHS I +S  WL+R
Sbjct: 896  IFSSDRTGLCQDHTDSHSVIGLSRHWLNR 924


>ref|XP_006345369.1| PREDICTED: DNA topoisomerase 2-binding protein 1-like [Solanum
            tuberosum]
          Length = 990

 Score =  810 bits (2091), Expect = 0.0
 Identities = 444/937 (47%), Positives = 587/937 (62%), Gaps = 62/937 (6%)
 Frame = -1

Query: 2687 KGCKLLGTELVISCGKENRALPKNKGFTCCLAMDGVKVLATGFDNKEKGKIEKLVTAMGG 2508
            KGC L+G + ++SC KE R LP+ +GFTCCLAMDGVK+LA+GF+  EK +I KLV AMGG
Sbjct: 69   KGCNLIGPQCILSCAKEQRPLPQ-QGFTCCLAMDGVKILASGFEMDEKVEIGKLVIAMGG 127

Query: 2507 VFQTRAALDTDFVICKNVLSGKYKWGLQTLKKPVITINWLYQCWSEHRLVPHEPCRVLPF 2328
            V QT+A+LD  FVI KNVL+ KYKW    LKKP++TINWL+QCW EHRLVP E  ++LPF
Sbjct: 128  VLQTKASLDVSFVIVKNVLAAKYKWAYNILKKPIVTINWLHQCWKEHRLVPQESFKILPF 187

Query: 2327 SGLTICFTRIAADVRKEMENLIVHNGGQYSGDLTRNCTHLISDAPEGDKYRVAQKWGHVR 2148
            SGLTI  TR+ AD RK+ME +I+ NGG+YS +LTR C+HLI D PEGDK++VA++WG + 
Sbjct: 188  SGLTISVTRVPADERKDMEKIILQNGGKYSPELTRKCSHLICDVPEGDKFKVAKRWGCIH 247

Query: 2147 IVTKDWLRDSFNRKVYLPEDAYLVQG-------ITMSANHVLKNELREKNYQDKKSTNSQ 1989
             VTK W   S  R+  L E++Y VQ        + M+  H L+  +R  N Q   S  + 
Sbjct: 248  TVTKRWFEQSVARRACLNEESYPVQAGSNTLSTVRMTNQHSLEKGIR--NLQGLSSLATA 305

Query: 1988 SGPGPI------AADSEATLXXXXXXXXXXXXXIMKGEEGIEAPPP-------------- 1869
            S   P+       +D EATL               K  E   A  P              
Sbjct: 306  SSAEPVFCSRVADSDLEATLSQNMSATSSYAPVFTKEPENSPAEYPKSDYSAPVSTKGKK 365

Query: 1868 --SKIEDKEETLDSCVADDSQSEDSGLYLSDCRILLVGFHAAEMRKLVNKVRRGGGSRYM 1695
              +  E +    D  VADDS+++D+ LYL+DCRIL+VGF+A+EMRKLVN VR+GGGSRYM
Sbjct: 366  SGASTEQENNGCDGVVADDSETDDNDLYLADCRILIVGFNASEMRKLVNLVRKGGGSRYM 425

Query: 1694 AFNDRLTHIVVGTPTENERRELRRYTAAGVIYVVRAVWLDDCDREKKELPVSKRHVVPDL 1515
            +F+++LTHI+ G P+ENE +ELR   A GVI+VV++ WL+DCDRE KE+PV ++H+  DL
Sbjct: 426  SFSEKLTHIIAGNPSENEIKELRNLAALGVIHVVKSGWLEDCDRENKEVPVLRKHIAYDL 485

Query: 1514 ILPKDSVCPDKATKIGT---RQGHNLITPPSVPDHL-----TQCFRPSMPREQTEERKTM 1359
            +LPKD +       I T   RQG + + P S  +       ++C  PS   ++ E    +
Sbjct: 486  LLPKDPIHCSNGAAITTTMKRQGKSYVHPMSSDEQAWRSRDSRCAMPSYENKELENMNDV 545

Query: 1358 EAS---------------KQESSMVKKNS--------SNIXXXXXXXXXXXFPLDRRAEI 1248
              S               K+E  +  ++S        S++           FP DRRAEI
Sbjct: 546  RTSLGENGVQHQPYASNGKEEFKIPNESSCAVNGRKPSSVFEGRQFCFSASFPADRRAEI 605

Query: 1247 VEWIKQGGGEIVDGQSEFNVNFTVECHGLV--TKAGNVSQSQTTIVSTHWIRSCLEDACM 1074
            VEW+ QGGG +V  Q++ NV+FTVECHG++   KAG    + TT VS+HWI+SCLED C+
Sbjct: 606  VEWVNQGGGVVVKDQNDTNVHFTVECHGMLRSEKAG----AATTFVSSHWIKSCLEDGCL 661

Query: 1073 PDVGSHIIYSPVPCKIPLPGFEAFRFCVSQYEEKDRLLLRNLCFVLGAKFTEKLSKKVTH 894
             DVG+HI+YSP+PC++P P F++FR CVSQY+EK+R LLRNLCF +GAKF EKL+KKVTH
Sbjct: 662  LDVGNHILYSPLPCRVPFPAFKSFRLCVSQYDEKERQLLRNLCFTIGAKFVEKLTKKVTH 721

Query: 893  LLCKFTNGPKYEAACKWGMQTVTSEWISECIRQNAVVSAHPFRPKEMTAQDREAGLATMS 714
            LLCKFT+GPKYEAACKWG+Q VT EWI ECI QN +VSA PF PKE+T++DREAG  T+S
Sbjct: 722  LLCKFTDGPKYEAACKWGIQPVTCEWIYECINQNKIVSADPFYPKEVTSEDREAGACTVS 781

Query: 713  QYTTQAARMISGEDVPSQSQGQSQFAMNSSRTFGKKSTNLSVEAEYPSATNKKRAKVSAN 534
            Q+ TQA  MISG+   + SQ   +     +  F  +ST    E +Y S  NKK   +   
Sbjct: 782  QFPTQAFGMISGD---TASQPLQELVNVRTEAFAGRST-AKEEKKYSSRWNKKARLLVVE 837

Query: 533  NDKIDLLPLDVCANVSSCTMKSIKTSEGGNIRDDGSHDVPDVAAAIEDLLEESSKIQDMA 354
              K   LP     + + C     + +  G+  ++GS  VPDVAAAIEDLLE++SKI D  
Sbjct: 838  EPKCS-LPCSPKESNAFCGASPPEKNLTGS-TNEGSSAVPDVAAAIEDLLEQTSKIHDQK 895

Query: 353  LSGRTISDRSIFSPDHSIITQNPATSHSAIQISTSWLSRKEKQDDGNQCDSSSVQGVNEH 174
               R+  D+ +F+   + + Q     H+ + +S  W +R EK+D     ++ S  G    
Sbjct: 896  SPSRSECDKELFTSGCNNLAQAHGDHHATLGLSNHWTNRFEKED-----ETQSHSGDATA 950

Query: 173  RTYDGFSETQTESQVVVYEEDLSGRQMMIDRHRTRSS 63
              YD FSETQT+SQVV Y EDLSGRQM+IDR RTRSS
Sbjct: 951  NVYDHFSETQTDSQVVGYAEDLSGRQMIIDRVRTRSS 987


>ref|XP_009788828.1| PREDICTED: DNA topoisomerase 2-binding protein 1 isoform X2
            [Nicotiana sylvestris]
          Length = 990

 Score =  807 bits (2084), Expect = 0.0
 Identities = 443/933 (47%), Positives = 579/933 (62%), Gaps = 58/933 (6%)
 Frame = -1

Query: 2687 KGCKLLGTELVISCGKENRALPKNKGFTCCLAMDGVKVLATGFDNKEKGKIEKLVTAMGG 2508
            KGC L+G + V+SC KE R LP+ +GFTCCLAMDGVK+LA+GF+  EK ++ KLV+AMGG
Sbjct: 69   KGCNLIGPQCVLSCAKEQRPLPQ-QGFTCCLAMDGVKILASGFEMDEKVELGKLVSAMGG 127

Query: 2507 VFQTRAALDTDFVICKNVLSGKYKWGLQTLKKPVITINWLYQCWSEHRLVPHEPCRVLPF 2328
            V  T+A+LD  FVI KNVL+ KYKW +  LKKP++TINWL QCW EHRLVP E  +VLPF
Sbjct: 128  VLHTKASLDVSFVIVKNVLAAKYKWAVNKLKKPIVTINWLQQCWKEHRLVPQESFKVLPF 187

Query: 2327 SGLTICFTRIAADVRKEMENLIVHNGGQYSGDLTRNCTHLISDAPEGDKYRVAQKWGHVR 2148
            SGLTIC TRI  D R+EME +I+ NGG+YS +LTR C+HLI +APEG+KY+VA++WGH+ 
Sbjct: 188  SGLTICVTRIPIDERREMEKIILQNGGKYSPELTRKCSHLICNAPEGEKYKVAKRWGHIH 247

Query: 2147 IVTKDWLRDSFNRKVYLPEDAYLVQG--------ITMSANHVLKNELREKNYQDKKSTNS 1992
             VTK W   S  R+  L E++Y VQ         + M+  H L+  +R  N Q   S  +
Sbjct: 248  TVTKRWFDQSVARRACLDEESYPVQAGSPNTMTTLRMTNQHSLEKGMR--NLQGLSSLAT 305

Query: 1991 QSGPGPI----AADS--EATLXXXXXXXXXXXXXIM------KGEEGIEAPPPSK----- 1863
             S   P+    A+DS  EATL              +        +    AP  +K     
Sbjct: 306  PSNAEPVLCSGASDSYVEATLSQDMPDTPVLTKKEVNLAPAENPKSDYSAPVSTKNEQSG 365

Query: 1862 --IEDKEETLDSCVADDSQSEDSGLYLSDCRILLVGFHAAEMRKLVNKVRRGGGSRYMAF 1689
              IE ++   D  VADD+Q++D+  YL+DCRIL+VGF+A+EMRKLVN VR+GGGSRYM+F
Sbjct: 366  APIEQEQNDCDGGVADDTQADDNDFYLADCRILIVGFNASEMRKLVNLVRKGGGSRYMSF 425

Query: 1688 NDRLTHIVVGTPTENERRELRRYTAAGVIYVVRAVWLDDCDREKKELPVSKRHVVPDLIL 1509
             ++LTHI+ G P+ENE +ELR   A GV++VV++ WL DCDREKKE+PV ++H+  DL+L
Sbjct: 426  GEKLTHIIAGNPSENEIKELRNLAALGVVHVVKSEWLQDCDREKKEVPVLRKHIAYDLLL 485

Query: 1508 PKDSVCPDKATKIGT---RQGHNLITPPSVPDHL-----TQCFRPSMPREQTEERKTMEA 1353
            PKD +         T   RQG +     S  +H      + C  PS   ++ E    +  
Sbjct: 486  PKDPIHCSNGAGTSTSMKRQGKSYGHTISSDEHAWRGTDSGCAMPSDKNKELENMNDIRT 545

Query: 1352 SKQESSMVK----------------------KNSSNIXXXXXXXXXXXFPLDRRAEIVEW 1239
            S +E+ +                        +  S++           FP+DRRAEIVEW
Sbjct: 546  SLRENGVQHQPYSSHHKDEKLLNESGCAVNGRKPSSVFEGRRFCFSASFPVDRRAEIVEW 605

Query: 1238 IKQGGGEIVDGQSEFNVNFTVECHGLVTKAGNVSQSQTTIVSTHWIRSCLEDACMPDVGS 1059
            + QGGG +V+ Q+E NV+FTVECHG  T       +  T VS+HWI+SCLED C+ DVGS
Sbjct: 606  VSQGGGVVVEDQTETNVHFTVECHG--TLCSEKDGAAATFVSSHWIKSCLEDGCLLDVGS 663

Query: 1058 HIIYSPVPCKIPLPGFEAFRFCVSQYEEKDRLLLRNLCFVLGAKFTEKLSKKVTHLLCKF 879
            HI+YSP+PC++P P F++FRFCVSQY+EK+R LLRNLCF +GAKF EKL+K+VTHLLCKF
Sbjct: 664  HILYSPLPCRVPFPAFQSFRFCVSQYDEKERQLLRNLCFTIGAKFAEKLTKRVTHLLCKF 723

Query: 878  TNGPKYEAACKWGMQTVTSEWISECIRQNAVVSAHPFRPKEMTAQDREAGLATMSQYTTQ 699
             +GPKYE ACKWG+Q VT EWI ECI+ N +VS  PF PKE+T++DREAG+ T SQ+ TQ
Sbjct: 724  ISGPKYEVACKWGIQPVTCEWIYECIKLNKIVSPDPFYPKEVTSEDREAGVCTTSQFPTQ 783

Query: 698  AARMISGEDVPSQSQGQSQFAMN-SSRTFGKKSTNLSVEAEYPSATNKKRAKVSANNDKI 522
            A RM SG D  SQ Q Q Q  +N  +  F  +S     E ++ S  NKK   +       
Sbjct: 784  AVRMTSG-DTSSQPQSQPQELINLRTEAFAGRSI-AKEEMKHSSRWNKKARLMVVEETNC 841

Query: 521  DLLPLDVCANVSSCTMKSIKTSEGGNIRDDGSHDVPDVAAAIEDLLEESSKIQDMALSGR 342
             L  +    N    T    K   G     +GS  VPDVAAAIEDLLE++SKI D     R
Sbjct: 842  SLTCVSNENNAFCGTNPPEKNMIGST--KEGSSAVPDVAAAIEDLLEQTSKIHDQKSPSR 899

Query: 341  TISDRSIFSPDHSIITQNPATSHSAIQISTSWLSRKEKQDDGNQCDSSSVQGVNEHRTYD 162
               D+ +F+   +I+ Q     H+ + +S  W +R EK+DD +     +   V     YD
Sbjct: 900  IECDKELFTSGCNILAQGHEDHHTTLGLSNDWTNRFEKKDDSHGHSGDATANV-----YD 954

Query: 161  GFSETQTESQVVVYEEDLSGRQMMIDRHRTRSS 63
             FSETQT+SQVV Y EDLSGRQM+IDR RTRSS
Sbjct: 955  HFSETQTDSQVVGYAEDLSGRQMIIDRVRTRSS 987


>ref|XP_014502699.1| PREDICTED: DNA topoisomerase 2-binding protein 1-A isoform X3 [Vigna
            radiata var. radiata]
          Length = 975

 Score =  803 bits (2073), Expect = 0.0
 Identities = 447/916 (48%), Positives = 581/916 (63%), Gaps = 41/916 (4%)
 Frame = -1

Query: 2687 KGCKLLGTELVISCGKENRALPKNKGFTCCLAMDGVKVLATGFDNKEKGKIEKLVTAMGG 2508
            KGCKLLG   V+SC K  R LPK +GFTCCLAMDGVKVLA+GFD +EK KIE+LV  MGG
Sbjct: 74   KGCKLLGPRCVLSCAKGGRPLPK-QGFTCCLAMDGVKVLASGFDTEEKVKIEELVAEMGG 132

Query: 2507 VFQTRAALDTDFVICKNVLSGKYKWGLQTLKKPVITINWLYQCWSEHRLVPHEPCRVLPF 2328
            V  T+ +LD +FVI KNVL+ KYKW L  LKKP++T  WL QC  EHR+VP E  +VLPF
Sbjct: 133  VLHTKTSLDLNFVIVKNVLARKYKWALNELKKPIVTYEWLKQCSEEHRVVPQESYKVLPF 192

Query: 2327 SGLTICFTRIAADVRKEMENLIVHNGGQYSGDLTRNCTHLISDAPEGDKYRVAQKWGHVR 2148
            SGL IC T I ADVRKEME LI+ NGG+YS +LT+NCTHLIS+AP+GDKY+VA++WGH+ 
Sbjct: 193  SGLKICVTGIPADVRKEMEKLILQNGGKYSAELTKNCTHLISEAPQGDKYKVAKRWGHIH 252

Query: 2147 IVTKDWLRDSFNRKVYLPEDAYLVQGITMSANHVLKNELREKNYQDKKSTNSQSGPGPIA 1968
            IV K W   S  R+  L E+ + VQ  ++S +H +  +L  ++ Q+K     QS      
Sbjct: 253  IVIKKWFDQSIARRACLNEEFFPVQHGSVS-SHKVTRDLTMQHSQEKDIGKLQSAASSGT 311

Query: 1967 ADSEATLXXXXXXXXXXXXXIMK----------GEEGIEAPPPSKIEDKEETLDSCVADD 1818
             DS   +               +            +  +A PP +    E  LD+ VADD
Sbjct: 312  TDSNVQVSCAEFRDRDHEAMPSEFMSSDSQTRIFAKEADAEPPLQTSG-ELNLDNIVADD 370

Query: 1817 SQSEDSGLYLSDCRILLVGFHAAEMRKLVNKVRRGGGSRYMAFNDRLTHIVVGTPTENER 1638
            S+S+D+ LYLS+CRILLVGF A EMRKL+N VR+GGGSRYM+FND+LTHIVVG PTE E+
Sbjct: 371  SESDDNDLYLSECRILLVGFEALEMRKLINIVRKGGGSRYMSFNDKLTHIVVGNPTEMEK 430

Query: 1637 RELRRYTAAGVIYVVRAVWLDDCDREKKELPVSKRHVVPDLILPKDSVCPDKATKIGTRQ 1458
            +++R   A GVIYVV+  WL+DCD +KKE+PV +RH+  DL+ PK+S   D +      Q
Sbjct: 431  KDVRSLAALGVIYVVKTSWLEDCDHKKKEVPVLRRHIAYDLLQPKESTSMDHSKSSSCHQ 490

Query: 1457 GHNLITPPSV-PDHLTQ-------------CFRP----SMPREQTEERK--TMEASKQES 1338
              + +   +V P+ L +              FR     +M + Q  + K  T   S+ + 
Sbjct: 491  SSHQVDFENVKPESLEKRKEQIKDMDINGHSFRKANCRTMLQNQLPDNKLSTQGMSQHDF 550

Query: 1337 SMVKKNSSNIXXXXXXXXXXXFPLDRRAEIVEWIKQGGGEIVDGQSEFNVNFTVECHGLV 1158
            S+  + S+N+           FP ++R EIV+WI QGGGE++ GQ+E  V++TVECHG+ 
Sbjct: 551  SVQYEKSANVFRGKLFCFSNLFPEEKRGEIVQWISQGGGEVISGQAEQIVHYTVECHGVT 610

Query: 1157 TKAGNVSQSQTTIVSTHWIRSCLEDACMPDVGSHIIYSPVPCKIPLPGFEAFRFCVSQYE 978
                    S++  VS+HWIRSCLE   + DVGSHI+YSP+PC +PLPGFE FRFCVSQYE
Sbjct: 611  PML--TGDSKSLSVSSHWIRSCLEAGSLLDVGSHILYSPLPCHVPLPGFERFRFCVSQYE 668

Query: 977  EKDRLLLRNLCFVLGAKFTEKLSKKVTHLLCKFTNGPKYEAACKWGMQTVTSEWISECIR 798
            EKDR LLRNLCFVLGAKF EKL KKVTHLLCKFTNGPKY+ A KWG+Q+VT EWI EC++
Sbjct: 669  EKDRNLLRNLCFVLGAKFGEKLHKKVTHLLCKFTNGPKYDGARKWGIQSVTCEWIFECVK 728

Query: 797  QNAVVSAHPFRPKEMTAQDREAGLATMSQYTTQAARMISGEDVPSQSQGQSQFAMN-SSR 621
            QN VV+   F PKE+TAQDREAGL T+SQ+ TQAA+MIS  D+PSQ   QSQ     + +
Sbjct: 729  QNGVVAVDQFLPKEVTAQDREAGLCTVSQFPTQAAQMIS--DMPSQLSSQSQILRGITDK 786

Query: 620  TFGKKSTNLSVEAEYPSATNKKRAKVSANNDKIDLLPLDVCANVSSCTMKSIKTSEGGNI 441
              G    N     + PS  +KK A++       + +P    A+ S         SE   +
Sbjct: 787  NVGCGVGNHETNFKKPSVYSKK-ARLVEEPCLSNKMP---SASNSGIHAYGKNFSEDNTL 842

Query: 440  RDDGS--HDVPDVAAAIEDLLEESSKIQDMALSGRTISDRSIFSPDHSIITQNPATSHSA 267
             D G     VPDVAAAIEDLLE++SK+        T  +R I+  D S++ ++ +  H+ 
Sbjct: 843  IDGGEVCRTVPDVAAAIEDLLEQTSKMHGQRSPAHTGCERGIYPSDLSVLGEDNSNPHTV 902

Query: 266  IQISTSWLS--------RKEKQDDGNQCDSSSVQGVNEHRTYDGFSETQTESQVVVYEED 111
              +S  WL+        R ++++D  +       G+     YDGFSETQTESQVV YEED
Sbjct: 903  FGLSKHWLNSTESIYSYRNDRKEDDGEASQDRPAGI-----YDGFSETQTESQVVSYEED 957

Query: 110  LSGRQMMIDRHRTRSS 63
            LSGRQ +ID++RTRSS
Sbjct: 958  LSGRQSLIDKYRTRSS 973


>ref|XP_009605009.1| PREDICTED: DNA topoisomerase 2-binding protein 1 [Nicotiana
            tomentosiformis]
          Length = 990

 Score =  803 bits (2073), Expect = 0.0
 Identities = 436/932 (46%), Positives = 584/932 (62%), Gaps = 57/932 (6%)
 Frame = -1

Query: 2687 KGCKLLGTELVISCGKENRALPKNKGFTCCLAMDGVKVLATGFDNKEKGKIEKLVTAMGG 2508
            KGC L+G + V+SC KE R LP+ +GFTCCLAMDGVK+LA+GF+  EK ++ KLV+AMGG
Sbjct: 69   KGCNLIGPQCVLSCAKEQRPLPQ-QGFTCCLAMDGVKILASGFEMDEKVELGKLVSAMGG 127

Query: 2507 VFQTRAALDTDFVICKNVLSGKYKWGLQTLKKPVITINWLYQCWSEHRLVPHEPCRVLPF 2328
            V  T+A+LD  FVI KNVL+ KYKW +  LKKP++TINWL QCW EHRLVP E  +VLPF
Sbjct: 128  VLHTKASLDVSFVIVKNVLAAKYKWAVNKLKKPIVTINWLQQCWKEHRLVPQESFKVLPF 187

Query: 2327 SGLTICFTRIAADVRKEMENLIVHNGGQYSGDLTRNCTHLISDAPEGDKYRVAQKWGHVR 2148
            SGLTIC TRI  D R+EME +I+ NGG+YS +LTR C+HLI +APEG+KY+VA++WGH+ 
Sbjct: 188  SGLTICVTRIPIDERREMEKIILQNGGKYSPELTRKCSHLICNAPEGEKYKVAKRWGHIH 247

Query: 2147 IVTKDWLRDSFNRKVYLPEDAYLVQG--------ITMSANHVLKNELREKNYQDKKSTNS 1992
             VTK W   S  R+  L E++Y VQ         + M   H L+  +R        +T S
Sbjct: 248  TVTKRWFDQSVARRACLDEESYPVQAGSPNTMTTLRMPNQHSLEKGMRNLQGLSSLATPS 307

Query: 1991 QSGPGPIAADSEATLXXXXXXXXXXXXXIMKGEEGI----------EAPPPSK------- 1863
             + P   +  +++ +             + K EE +           AP  +K       
Sbjct: 308  NAEPVLCSGATDSYVEATLSQDMPDAPVLTKEEENLAPAENPKSDYSAPVSTKDEQSGAP 367

Query: 1862 IEDKEETLDSCVADDSQSEDSGLYLSDCRILLVGFHAAEMRKLVNKVRRGGGSRYMAFND 1683
            IE ++   D  VADDSQ++D+  YL+DCRIL+VGF+A+EMRKLVN VR+GGGSRYM+F +
Sbjct: 368  IEQEKNDCDGGVADDSQTDDNDFYLADCRILIVGFNASEMRKLVNLVRKGGGSRYMSFGE 427

Query: 1682 RLTHIVVGTPTENERRELRRYTAAGVIYVVRAVWLDDCDREKKELPVSKRHVVPDLILPK 1503
            +LTHI+ G P+E E +ELR   A GVI+VV++ WL DCD EKKE+PV ++H+  DL+LPK
Sbjct: 428  KLTHIIAGNPSEFEIKELRNLAALGVIHVVKSGWLQDCDLEKKEVPVLRKHIAYDLLLPK 487

Query: 1502 DSVCPDKATKIGT---RQGHNLITPPSVPDHL-----TQCFRPSMPREQTEERKTMEASK 1347
            D +         T   RQG + +   S  +H      + C  PS   ++ E    +  S 
Sbjct: 488  DPIHCSNGAGTSTSMKRQGKSYVHTMSSDEHAWRGTDSGCAMPSDKNKELENMNDIRTSL 547

Query: 1346 QESSMVK----------------------KNSSNIXXXXXXXXXXXFPLDRRAEIVEWIK 1233
            +E+ +                        +  S++           FP+DRR EIVEW+ 
Sbjct: 548  RENGVQHQPYSSNSKDEKLVNESGCAVNGRKPSSVFEGRRFCFSASFPVDRRTEIVEWVS 607

Query: 1232 QGGGEIVDGQSEFNVNFTVECHGLV--TKAGNVSQSQTTIVSTHWIRSCLEDACMPDVGS 1059
            QGGG +V+ Q+E NV+FTVECHG++   K G V+    T VS+HWI+SCLED C+ DVGS
Sbjct: 608  QGGGVVVEDQTETNVHFTVECHGMLRSEKDGAVA----TFVSSHWIKSCLEDGCLLDVGS 663

Query: 1058 HIIYSPVPCKIPLPGFEAFRFCVSQYEEKDRLLLRNLCFVLGAKFTEKLSKKVTHLLCKF 879
            H++YSP+PC++P P F++FR CVSQY+EK++ LLRNLCF +GAKF EKL+K+VTHLLCKF
Sbjct: 664  HVLYSPLPCRVPFPAFQSFRLCVSQYDEKEKQLLRNLCFTIGAKFVEKLTKRVTHLLCKF 723

Query: 878  TNGPKYEAACKWGMQTVTSEWISECIRQNAVVSAHPFRPKEMTAQDREAGLATMSQYTTQ 699
            T+GPKYEAACKWG+Q VT EWI ECI+QN +VS   F PKE+TA+DREAG+ TMSQ+ TQ
Sbjct: 724  TSGPKYEAACKWGIQPVTCEWIYECIKQNKIVSPDQFYPKEVTAEDREAGVCTMSQFPTQ 783

Query: 698  AARMISGEDVPSQSQGQSQFAMNSSRTFGKKSTNLSVEAEYPSATNKKRAKVSANNDKID 519
            A RMIS  D  SQ Q Q Q  +N  RT      +++ E    S+   K+A++    +   
Sbjct: 784  AVRMIS-SDTSSQPQSQPQELIN-LRTEAFAGRSIAKEEMKHSSRWNKKARLLVVEETNC 841

Query: 518  LLPLDVCANVSSCTMKSIKTSEGGNIRDDGSHDVPDVAAAIEDLLEESSKIQDMALSGRT 339
             L      N + C     + +  G+ ++D S  VPDVAAAIEDLLE++SKI D     R 
Sbjct: 842  SLTCVSNENNAFCGTNPPEKNMIGSTKEDSS-AVPDVAAAIEDLLEQTSKIHDQKSPSRI 900

Query: 338  ISDRSIFSPDHSIITQNPATSHSAIQISTSWLSRKEKQDDGNQCDSSSVQGVNEHRTYDG 159
              D+ +F+   + + Q     H+ + +S  W +R EK+DD +     +   V     YD 
Sbjct: 901  ECDKELFTSGCNTLAQGHGDHHATLGLSNHWTNRFEKKDDSHGHSGDATANV-----YDH 955

Query: 158  FSETQTESQVVVYEEDLSGRQMMIDRHRTRSS 63
            FSETQT+SQVV Y EDLSGRQM+IDR RTRSS
Sbjct: 956  FSETQTDSQVVGYAEDLSGRQMIIDRVRTRSS 987


>ref|XP_009788827.1| PREDICTED: DNA topoisomerase 2-binding protein 1 isoform X1
            [Nicotiana sylvestris]
          Length = 995

 Score =  799 bits (2063), Expect = 0.0
 Identities = 442/938 (47%), Positives = 579/938 (61%), Gaps = 63/938 (6%)
 Frame = -1

Query: 2687 KGCKLLGTELVISCGKENRALPKNKGFTCCLAMDGVKVLATGFDNKEKGKIEKLVTAMGG 2508
            KGC L+G + V+SC KE R LP+ +GFTCCLAMDGVK+LA+GF+  EK ++ KLV+AMGG
Sbjct: 69   KGCNLIGPQCVLSCAKEQRPLPQ-QGFTCCLAMDGVKILASGFEMDEKVELGKLVSAMGG 127

Query: 2507 VFQTRAALDTDFVICKNVLSGKYKWGLQTLKKPVITINWLYQCWSEHRLVPHEPCRVLPF 2328
            V  T+A+LD  FVI KNVL+ KYKW +  LKKP++TINWL QCW EHRLVP E  +VLPF
Sbjct: 128  VLHTKASLDVSFVIVKNVLAAKYKWAVNKLKKPIVTINWLQQCWKEHRLVPQESFKVLPF 187

Query: 2327 SGLTICFTRIAADVRKEMENLIVHNGGQYSGDLTRNCTHLISDAPEGDKYRVAQKWGHVR 2148
            SGLTIC TRI  D R+EME +I+ NGG+YS +LTR C+HLI +APEG+KY+VA++WGH+ 
Sbjct: 188  SGLTICVTRIPIDERREMEKIILQNGGKYSPELTRKCSHLICNAPEGEKYKVAKRWGHIH 247

Query: 2147 IVTKDWLRDSFNRKVYLPEDAYLVQG--------ITMSANHVLKNELREKNYQDKKSTNS 1992
             VTK W   S  R+  L E++Y VQ         + M+  H L+  +R  N Q   S  +
Sbjct: 248  TVTKRWFDQSVARRACLDEESYPVQAGSPNTMTTLRMTNQHSLEKGMR--NLQGLSSLAT 305

Query: 1991 QSGPGPI----AADS--EATLXXXXXXXXXXXXXIM------KGEEGIEAPPPSK----- 1863
             S   P+    A+DS  EATL              +        +    AP  +K     
Sbjct: 306  PSNAEPVLCSGASDSYVEATLSQDMPDTPVLTKKEVNLAPAENPKSDYSAPVSTKNEQSG 365

Query: 1862 --IEDKEETLDSCVADDSQSEDSGLYLSDCRILLVGFHAAEMRKLVNKVRRGGGSRYMAF 1689
              IE ++   D  VADD+Q++D+  YL+DCRIL+VGF+A+EMRKLVN VR+GGGSRYM+F
Sbjct: 366  APIEQEQNDCDGGVADDTQADDNDFYLADCRILIVGFNASEMRKLVNLVRKGGGSRYMSF 425

Query: 1688 NDRLTHIVVGTPTE-----NERRELRRYTAAGVIYVVRAVWLDDCDREKKELPVSKRHVV 1524
             ++LTHI+ G P+E     +E +ELR   A GV++VV++ WL DCDREKKE+PV ++H+ 
Sbjct: 426  GEKLTHIIAGNPSEKLLSCSEIKELRNLAALGVVHVVKSEWLQDCDREKKEVPVLRKHIA 485

Query: 1523 PDLILPKDSVCPDKATKIGT---RQGHNLITPPSVPDHL-----TQCFRPSMPREQTEER 1368
             DL+LPKD +         T   RQG +     S  +H      + C  PS   ++ E  
Sbjct: 486  YDLLLPKDPIHCSNGAGTSTSMKRQGKSYGHTISSDEHAWRGTDSGCAMPSDKNKELENM 545

Query: 1367 KTMEASKQESSMVK----------------------KNSSNIXXXXXXXXXXXFPLDRRA 1254
              +  S +E+ +                        +  S++           FP+DRRA
Sbjct: 546  NDIRTSLRENGVQHQPYSSHHKDEKLLNESGCAVNGRKPSSVFEGRRFCFSASFPVDRRA 605

Query: 1253 EIVEWIKQGGGEIVDGQSEFNVNFTVECHGLVTKAGNVSQSQTTIVSTHWIRSCLEDACM 1074
            EIVEW+ QGGG +V+ Q+E NV+FTVECHG  T       +  T VS+HWI+SCLED C+
Sbjct: 606  EIVEWVSQGGGVVVEDQTETNVHFTVECHG--TLCSEKDGAAATFVSSHWIKSCLEDGCL 663

Query: 1073 PDVGSHIIYSPVPCKIPLPGFEAFRFCVSQYEEKDRLLLRNLCFVLGAKFTEKLSKKVTH 894
             DVGSHI+YSP+PC++P P F++FRFCVSQY+EK+R LLRNLCF +GAKF EKL+K+VTH
Sbjct: 664  LDVGSHILYSPLPCRVPFPAFQSFRFCVSQYDEKERQLLRNLCFTIGAKFAEKLTKRVTH 723

Query: 893  LLCKFTNGPKYEAACKWGMQTVTSEWISECIRQNAVVSAHPFRPKEMTAQDREAGLATMS 714
            LLCKF +GPKYE ACKWG+Q VT EWI ECI+ N +VS  PF PKE+T++DREAG+ T S
Sbjct: 724  LLCKFISGPKYEVACKWGIQPVTCEWIYECIKLNKIVSPDPFYPKEVTSEDREAGVCTTS 783

Query: 713  QYTTQAARMISGEDVPSQSQGQSQFAMN-SSRTFGKKSTNLSVEAEYPSATNKKRAKVSA 537
            Q+ TQA RM SG D  SQ Q Q Q  +N  +  F  +S     E ++ S  NKK   +  
Sbjct: 784  QFPTQAVRMTSG-DTSSQPQSQPQELINLRTEAFAGRSI-AKEEMKHSSRWNKKARLMVV 841

Query: 536  NNDKIDLLPLDVCANVSSCTMKSIKTSEGGNIRDDGSHDVPDVAAAIEDLLEESSKIQDM 357
                  L  +    N    T    K   G     +GS  VPDVAAAIEDLLE++SKI D 
Sbjct: 842  EETNCSLTCVSNENNAFCGTNPPEKNMIGST--KEGSSAVPDVAAAIEDLLEQTSKIHDQ 899

Query: 356  ALSGRTISDRSIFSPDHSIITQNPATSHSAIQISTSWLSRKEKQDDGNQCDSSSVQGVNE 177
                R   D+ +F+   +I+ Q     H+ + +S  W +R EK+DD +     +   V  
Sbjct: 900  KSPSRIECDKELFTSGCNILAQGHEDHHTTLGLSNDWTNRFEKKDDSHGHSGDATANV-- 957

Query: 176  HRTYDGFSETQTESQVVVYEEDLSGRQMMIDRHRTRSS 63
               YD FSETQT+SQVV Y EDLSGRQM+IDR RTRSS
Sbjct: 958  ---YDHFSETQTDSQVVGYAEDLSGRQMIIDRVRTRSS 992


>ref|XP_008444199.1| PREDICTED: DNA topoisomerase 2-binding protein 1 isoform X2 [Cucumis
            melo]
          Length = 970

 Score =  795 bits (2053), Expect = 0.0
 Identities = 443/927 (47%), Positives = 583/927 (62%), Gaps = 50/927 (5%)
 Frame = -1

Query: 2687 KGCKLLGTELVISCGKENRALPKNKGFTCCLAMDGVKVLATGFDNKEKGKIEKLVTAMGG 2508
            KGC LLG + V+SC KE+R LP+ +G+TCCLAMDGVK+LA+GF   EK +I KLV+AMGG
Sbjct: 69   KGCNLLGPQCVMSCAKEHRPLPQ-QGYTCCLAMDGVKILASGFQEDEKAEIGKLVSAMGG 127

Query: 2507 VFQTRAALDTDFVICKNVLSGKYKWGLQTLKKPVITINWLYQCWSEHRLVPHEPCRVLPF 2328
            V  T+A+LD  FVI KN L+ KYKW L   KKP+++ +WL QCW EHR+VP E  RVLPF
Sbjct: 128  VLYTKASLDVSFVIAKNALAAKYKWALNISKKPIVSFSWLQQCWIEHRVVPQEGYRVLPF 187

Query: 2327 SGLTICFTRIAADVRKEMENLIVHNGGQYSGDLTRNCTHLISDAPEGDKYRVAQKWGHVR 2148
            SGL I  +RI A  RKEME LI+ NGG+YS DLTR CTHLI DAPEGDKY+VA+ WG + 
Sbjct: 188  SGLNISVSRIPAGERKEMEKLILQNGGRYSADLTRKCTHLICDAPEGDKYKVARTWGRIN 247

Query: 2147 IVTKDWLRDSFNRKVYLPEDAYLVQGITMSANHVLKNELREKNYQDKKSTNSQSGPGPIA 1968
            IVT+ W   S  RK  L E+ Y V G++ ++N + ++ L   N Q+K + N Q+ P    
Sbjct: 248  IVTRKWFDQSIARKACLSEELYPVGGVSGTSNKLTRSCLTAHNSQEKVTGNLQAAPSSFF 307

Query: 1967 ADSEATLXXXXXXXXXXXXXIMKGEEG-----------IEAPPPSKIEDKEETLDSCVAD 1821
            ADS  T               +                ++   P      EE   +C+A+
Sbjct: 308  ADSSFTAVSGPGFSDMDVEATLSQSTSMFSDASHFINEVDVEVPVATGRNEENTVNCLAN 367

Query: 1820 DSQSEDSGLYLSDCRILLVGFHAAEMRKLVNKVRRGGGSRYMAFNDRLTHIVVGTPTENE 1641
            D QSE++ LYLS CRI +VGF A+EMRK+VN + RGGGSRYM FND+LTHI+VG  +E E
Sbjct: 368  DFQSEENDLYLSACRIKVVGFEASEMRKIVNMILRGGGSRYMLFNDKLTHIIVGNLSEME 427

Query: 1640 RRELRRYTAAGVIYVVRAVWLDDCDREKKELPVSKRHVVPDLILPKDSVCPDKATKIGTR 1461
            ++E+R   A+GV++VVR  WL+DCDR+KKE+P+  RH+  D ++PK S    K + I   
Sbjct: 428  KKEVRDIAASGVVHVVRTNWLEDCDRQKKEIPILGRHMAYDELIPKAS---SKMSTIVID 484

Query: 1460 QGH----NLITPPSVPD---HLTQCFRPSMPREQTEER---------------------- 1368
            +      + I P  VP+   H++   + SM  E+ EE+                      
Sbjct: 485  RSKVPNVHPIVPSIVPEGNIHVSTG-KTSMTVERIEEKSETKVNGDRKMKLSQKSQQCVP 543

Query: 1367 ----KTMEASKQESSMVKKNSSNIXXXXXXXXXXXFPLDRRAEIVEWIKQGGGEIVDGQS 1200
                K+ E   ++  +    SS +           FP DRRAEIVEWI QGGGE+V+   
Sbjct: 544  NGTNKSQEKMARDFMVSNGKSSCVFKGKIFCFSSSFPEDRRAEIVEWINQGGGEVVEDHM 603

Query: 1199 EFNVNFTVECHGLVTKAGNVSQSQTTIVSTHWIRSCLEDACMPDVGSHIIYSPVPCKIPL 1020
            +  V+FTVECHG + ++ +V    +T VS+HW+RSCLED C+     HI+YSP+PC +PL
Sbjct: 604  KQKVHFTVECHGGIPRSTDV---HSTYVSSHWVRSCLEDGCLWATNGHILYSPLPCCVPL 660

Query: 1019 PGFEAFRFCVSQYEEKDRLLLRNLCFVLGAKFTEKLSKKVTHLLCKFTNGPKYEAACKWG 840
             GFE  RFCVSQY++KDR+LLRNLCFVLGAKF EKL+KKVTHL+CKFT+G KYEAACKWG
Sbjct: 661  SGFENIRFCVSQYDDKDRVLLRNLCFVLGAKFVEKLTKKVTHLICKFTDGTKYEAACKWG 720

Query: 839  MQTVTSEWISECIRQNAVVSAHPFRPKEMTAQDREAGLATMSQYTTQAARMISGEDVPSQ 660
            +Q +T+EWI EC+RQ+ +VS   +RPKE+TAQDR AGL T+SQ+ TQAA MI+ E +   
Sbjct: 721  IQCITAEWIYECVRQSKIVSLDLYRPKEVTAQDRAAGLCTVSQFPTQAAPMIANESI--- 777

Query: 659  SQGQSQFAMNSS--RTFGKKSTNLSVEA-EYPSATNKKRAKVSANNDKIDLLPLDVCANV 489
                SQF ++S+  R     + N S+EA E  S+T KKR        K  L  L   +  
Sbjct: 778  ----SQFPIHSTIPRDQSAGTNNSSIEAVEQISSTKKKRKLFDEAIQKRPLF-LGNSSTQ 832

Query: 488  SSCTMKSIK--TSEGGNIRDDGSHDVPDVAAAIEDLLEESSKIQDMALSGRTISDRSIFS 315
            S C + S K  TS+   +    +  VPDVA+AIEDLLE+++KIQD    G+T  D+SIF 
Sbjct: 833  SDCNLNSTKQTTSKSSVV----TTHVPDVASAIEDLLEQTTKIQDQKSPGKTGCDKSIFP 888

Query: 314  PDHSIITQNPATSHSAIQISTSWLSRKEKQDD-GNQCDSSSVQGVNEHRTYDGFSETQTE 138
            PD S++ Q+ + +     IS  W  R E+++D  N        G+     YDGFSETQTE
Sbjct: 889  PDCSLVGQDHSETSQIGGISNQWSKRAERKEDVSNSTAEDGTVGI-----YDGFSETQTE 943

Query: 137  SQVVVYEEDLSGRQMMIDRHRTRSSMT 57
            SQVV YEEDLSGRQM++D+ RTRSSMT
Sbjct: 944  SQVVGYEEDLSGRQMLLDKVRTRSSMT 970


>emb|CDP16447.1| unnamed protein product [Coffea canephora]
          Length = 962

 Score =  792 bits (2046), Expect = 0.0
 Identities = 436/919 (47%), Positives = 579/919 (63%), Gaps = 42/919 (4%)
 Frame = -1

Query: 2687 KGCKLLGTELVISCGKENRALPKNKGFTCCLAMDGVKVLATGFDNKEKGKIEKLVTAMGG 2508
            KGC LLG + V+SC KE+R LPK +GFTCCLAMDGVK+L +GF+  E+ +I KLVT+MGG
Sbjct: 68   KGCNLLGPQCVLSCAKEHRPLPK-QGFTCCLAMDGVKLLTSGFEMDERAEIAKLVTSMGG 126

Query: 2507 VFQTRAALDTDFVICKNVLSGKYKWGLQTLKKPVITINWLYQCWSEHRLVPHEPCRVLPF 2328
            V QT+A++D +FVI KNVL+ KYKW L  LKKP++TINWL+QCW EHR+VP +  RV PF
Sbjct: 127  VLQTKASMDVNFVIVKNVLAAKYKWALNVLKKPIVTINWLHQCWREHRVVPQDSFRVPPF 186

Query: 2327 SGLTICFTRIAADVRKEMENLIVHNGGQYSGDLTRNCTHLI----SDAPEGDKYRVAQKW 2160
            SGLT+C +RI AD RK++E LI+ NGG+YS +LTR CTHL+    S APEGDKY+VA++W
Sbjct: 187  SGLTVCVSRIPADERKQLEQLILQNGGKYSAELTRKCTHLMFLDYSYAPEGDKYKVAKRW 246

Query: 2159 GHVRIVTKDWLRDSFNRKVYLPEDAYLVQGITMSANHVLKNELREKNYQDKKSTNSQSG- 1983
            GH+ I+++ W   S  R+  L E++Y VQG +M     +    ++K+  + +   S +G 
Sbjct: 247  GHIHIISRKWFDQSVARRACLNEESYPVQGSSMKTVRKMAMPSQDKSLGNSQCEASSAGT 306

Query: 1982 ------------PGPIAADSEATLXXXXXXXXXXXXXIMKGEEGIEAPPPSKIEDKEETL 1839
                        P P    SEA +               + E+  ++    K       +
Sbjct: 307  ASDPHVRQYAQKPEP---SSEANISHDMSSAFCDAPTFTREEDNGQSAEQLK---NNSNV 360

Query: 1838 DSCVADDSQSEDSGLYLSDCRILLVGFHAAEMRKLVNKVRRGGGSRYMAFNDRLTHIVVG 1659
            D CVADDSQ+ED  LYLS CRI+LVGF+A  MRKLV+ VRRGGGSRYM+FN++LTHI+VG
Sbjct: 361  DGCVADDSQTEDD-LYLSVCRIMLVGFNADNMRKLVSMVRRGGGSRYMSFNEKLTHIIVG 419

Query: 1658 TPTENERRELRRYTAAGVIYVVRAVWLDDCDREKKELPVSKRHVVPDLILPKDSVCPDKA 1479
            TP+E+E +E+R   A GVIYVV++ WL+DCDR+KKE+PV KRH+  DLILPKD++  +K 
Sbjct: 420  TPSESEIKEVRNLAALGVIYVVKSEWLEDCDRQKKEVPVLKRHMAYDLILPKDTINSNKR 479

Query: 1478 TKIGT---RQGHNLITPPSVPDHLTQCFRPSMPREQTEERK--------------TMEAS 1350
            + +     RQG ++   P +PD     +  S      E+RK              T   +
Sbjct: 480  SFMAMNEMRQGSSV--QPILPDDHIVKYTNSQSGVSFEKRKEVYSIRNEEMSWVNTGNLA 537

Query: 1349 KQESSMVK--------KNSSNIXXXXXXXXXXXFPLDRRAEIVEWIKQGGGEIVDGQSEF 1194
            KQ+ S  K        + S+N+           FP D+RAEIVEW+ QGGGE+V+   E 
Sbjct: 538  KQQQSTQKSASHDRDNRISANVFAGKLFCFSGSFPADQRAEIVEWVNQGGGEVVENLVEG 597

Query: 1193 NVNFTVECHGLVTKAGNVSQSQTTIVSTHWIRSCLEDACMPDVGSHIIYSPVPCKIPLPG 1014
            N  F VECHG+V    + S S+   VS+HWIRS L D  + DV SHI+YSP+PC++P   
Sbjct: 598  NTYFIVECHGVVPSETDFSGSK--YVSSHWIRSSLMDGHLLDVSSHILYSPLPCQVPFMS 655

Query: 1013 FEAFRFCVSQYEEKDRLLLRNLCFVLGAKFTEKLSKKVTHLLCKFTNGPKYEAACKWGMQ 834
            F+ FRFCVSQY+EK+RLLLRNLCF+LG +F EKL+KKVTHLLCKF +GPKYEAACKWG+Q
Sbjct: 656  FKCFRFCVSQYDEKERLLLRNLCFILGVQFVEKLTKKVTHLLCKFASGPKYEAACKWGIQ 715

Query: 833  TVTSEWISECIRQNAVVSAHPFRPKEMTAQDREAGLATMSQYTTQAARMISGEDVPSQSQ 654
             VTSEWI EC++QN VVS  PF PKE T+QDRE G+ TM+QY TQ   +ISG+D     +
Sbjct: 716  PVTSEWIYECVKQNKVVSPGPFCPKEATSQDRETGVCTMTQYPTQGIGIISGDDASQLPR 775

Query: 653  GQSQFAMNSSRTFGKKSTNLSVEAEYPSATNKKRAKVSANNDKIDLLPLDVCANVSSCTM 474
               +     +  F KKS     E  YP    KK     A+  K      ++  ++   + 
Sbjct: 776  HSQECKSVETEAFTKKSE----EINYPIGCLKKARTFEADKTKCSFSEANLTHSICRVSP 831

Query: 473  KSIKTSEGGNIRDDGSHDVPDVAAAIEDLLEESSKIQDMALSGRTISDRSIFSPDHSIIT 294
                 +E  +     +  VPDVAAAIEDLLE++SKI D     R+    SIF+ D +++ 
Sbjct: 832  MEEDVTENAS---KVTTMVPDVAAAIEDLLEQTSKIHDQQSPVRSTCGTSIFTSDCTVLG 888

Query: 293  QNPATSHSAIQISTSWLSRKEKQDDGNQCDSSSVQGVNEHRTYDGFSETQTESQVVVYEE 114
            Q+     SA+ +   W +R +K+D     DS + Q       YDGF+ET TESQVV Y +
Sbjct: 889  QDRGEPQSALGLPKHWKNRFDKKD-----DSHNPQEDARTNDYDGFTETPTESQVVGYAD 943

Query: 113  DLSGRQMMIDRHRTRSSMT 57
            DLSGRQM+IDR RTR+SMT
Sbjct: 944  DLSGRQMIIDRVRTRNSMT 962


>ref|XP_007019213.1| Topbp1, putative isoform 5 [Theobroma cacao]
            gi|508724541|gb|EOY16438.1| Topbp1, putative isoform 5
            [Theobroma cacao]
          Length = 894

 Score =  782 bits (2020), Expect = 0.0
 Identities = 435/826 (52%), Positives = 558/826 (67%), Gaps = 52/826 (6%)
 Frame = -1

Query: 2687 KGCKLLGTELVISCGKENRALPKNKGFTCCLAMDGVKVLATGFDNKEKGKIEKLVTAMGG 2508
            KGC LLG + V+SC KENRALPK +GFTCCLAMDG+KVLA+GFD  EK KIEKLVTAMGG
Sbjct: 71   KGCNLLGPQCVLSCAKENRALPK-QGFTCCLAMDGLKVLASGFDMDEKVKIEKLVTAMGG 129

Query: 2507 VFQTRAALDTDFVICKNVLSGKYKWGLQTLKKPVITINWLYQCWSEHRLVPHEPCRVLPF 2328
            V  T+A+LD  FV+ KNVL+ KYKW L  LKKP++T++WLYQCW EHR+VP E  RVLPF
Sbjct: 130  VLHTKASLDVSFVVVKNVLAAKYKWALNVLKKPIVTLHWLYQCWGEHRVVPQESYRVLPF 189

Query: 2327 SGLTICFTRIAADVRKEMENLIVHNGGQYSGDLTRNCTHLISDAPEGDKYRVAQKWGHVR 2148
            SGLTIC TRI AD RKE+E LI+ NGG+YS +LT+ CTHLI DAPEGDKY+VA++WGHV 
Sbjct: 190  SGLTICVTRIPADERKEIEKLIIQNGGKYSAELTKKCTHLICDAPEGDKYKVARRWGHVH 249

Query: 2147 IVTKDWLRDSFNRKVYLPEDAYLVQGITMSANHVLKNELREKNYQDKKSTNSQSGPGPIA 1968
            IV + W   S  R+  L E++Y VQG   S+   +   L  ++ QDK   +S S    + 
Sbjct: 250  IVVRKWFDQSIARRACLNEESYPVQGGCSSSKKNVSGSLSTQHSQDKFRGSSLSATSLMI 309

Query: 1967 ADS---------------EATLXXXXXXXXXXXXXIMKGEEGIEAPPPSKIEDKEET-LD 1836
            +D                EATL             I+K E+G EAP    ++   ET LD
Sbjct: 310  SDFNLSTVPPTGVGDPDLEATLSQNIPSMVSDAQVIVK-EDGGEAPT---LQPSNETKLD 365

Query: 1835 SCVADDSQSEDSGLYLSDCRILLVGFHAAEMRKLVNKVRRGGGSRYMAFNDRLTHIVVGT 1656
             CVA+DS+SED+ LYLSDCRI LVGF A+EMRKLV  VRRGGGSRYM+ ND+LTHIVVGT
Sbjct: 366  GCVANDSESEDNDLYLSDCRISLVGFEASEMRKLVMMVRRGGGSRYMSCNDKLTHIVVGT 425

Query: 1655 PTENERRELRRYTAAGVIYVVRAVWLDDCDREKKELPVSKRHVVPDLILPKDSVCPDKAT 1476
            P+E E++E+R + A+GV+ VV++ WL+DCDR+KKE+PV +RH+  DL+LPKDSV   K  
Sbjct: 426  PSEVEKKEVRSFAASGVMQVVKSNWLEDCDRQKKEIPVQQRHIAYDLLLPKDSVQSVKGA 485

Query: 1475 KIG---TRQGHNLITPPS-------VPDHLTQCFRPSMPREQTEERKTMEASKQE----- 1341
             IG   + Q  + +   S       + D+L    + +   +++ E  T+ +SKQ      
Sbjct: 486  VIGMVSSNQSKSSVLANSGTGMSSFLGDNLDDKTKINRNGDKSLEA-TVRSSKQGVPPTV 544

Query: 1340 ------------SSMVK--KN--SSNIXXXXXXXXXXXFPLDRRAEIVEWIKQGGGEIVD 1209
                         S+V   KN  SS +           FP DRRAEIVEW+ QGGGE+VD
Sbjct: 545  NSTNNGWQKQHCGSIVLNLKNGMSSTVFKGKIFCFSNSFPEDRRAEIVEWVDQGGGEVVD 604

Query: 1208 GQSEFNVNFTVECHGLVTKAGNVSQSQTTIVSTHWIRSCLEDACMPDVGSHIIYSPVPCK 1029
               + +VNF +ECHG+++++  +  SQ T VSTHW+RSCLED C+ DVG HI+YSP+PC+
Sbjct: 605  DHVKQSVNFIIECHGVISRS--IIDSQITYVSTHWVRSCLEDGCLLDVGCHILYSPLPCQ 662

Query: 1028 IPLPGFEAFRFCVSQYEEKDRLLLRNLCFVLGAKFTEKLSKKVTHLLCKFTNGPKYEAAC 849
            IP PGF++FRFCVSQYEEKDRLLLRNLCF+LGAKF EKL+KKVTHLLCKFT+GPKYEAAC
Sbjct: 663  IPFPGFKSFRFCVSQYEEKDRLLLRNLCFILGAKFVEKLTKKVTHLLCKFTSGPKYEAAC 722

Query: 848  KWGMQTVTSEWISECIRQNAVVSAHPFRPKEMTAQDREAGLATMSQYTTQAARMISGEDV 669
            KWG+ +VT+EWI EC+ QN VVS  PF PKE+TAQDREAGL T+SQ+ TQA +M+S  D+
Sbjct: 723  KWGIYSVTAEWIYECVSQNKVVSLDPFFPKEVTAQDREAGLCTVSQFPTQAVQMMS-VDI 781

Query: 668  PSQSQGQSQFAMNSSRTFGKKSTNL---SVEAEYPSATNKKRAKVSANNDKIDLLP--LD 504
            PSQ   QSQ     ++T G K  ++     EAE  S  + KRA+    +D+  LL   + 
Sbjct: 782  PSQFMTQSQDL--RTQTLGGKIESIIGGRDEAE-QSNVHLKRARCMEEDDQNGLLASVVH 838

Query: 503  VCANVSSCTMKSIKTSEGGNIRDDGSHDVPDVAAAIEDLLEESSKI 366
            +C  V +   ++   +    I  + +  +PDVAAAIEDLLE++SK+
Sbjct: 839  LCEPVLN---ENSTENNKSKIVGEAAQVLPDVAAAIEDLLEQTSKV 881


>ref|XP_012464227.1| PREDICTED: DNA topoisomerase 2-binding protein 1-A isoform X2
            [Gossypium raimondii]
          Length = 937

 Score =  782 bits (2019), Expect = 0.0
 Identities = 438/877 (49%), Positives = 561/877 (63%), Gaps = 55/877 (6%)
 Frame = -1

Query: 2687 KGCKLLGTELVISCGKENRALPKNKGFTCCLAMDGVKVLATGFDNKEKGKIEKLVTAMGG 2508
            KGC L+G + VISC  ENRALPK +GF+CCLAMDG+KVLA+GFD  EK KIEKLV AMGG
Sbjct: 72   KGCNLIGPQCVISCANENRALPK-QGFSCCLAMDGLKVLASGFDMDEKVKIEKLVIAMGG 130

Query: 2507 VFQTRAALDTDFVICKNVLSGKYKWGLQTLKKPVITINWLYQCWSEHRLVPHEPCRVLPF 2328
            V  T+A+LD  FVI KNVL+ KYKW L  LKKP++TI WLYQCWSEHR+VP E  RVLPF
Sbjct: 131  VLHTKASLDVSFVIVKNVLAAKYKWALNVLKKPIVTIQWLYQCWSEHRVVPQESYRVLPF 190

Query: 2327 SGLTICFTRIAADVRKEMENLIVHNGGQYSGDLTRNCTHLISDAPEGDKYRVAQKWGHVR 2148
            +GLTI  T I AD RKE+E LI+ NGG+YS +LT+ CTHLI D PEGDKY+VA++WGHV 
Sbjct: 191  TGLTISVTGIRADERKEIEKLIIQNGGKYSAELTKKCTHLICDVPEGDKYKVARRWGHVH 250

Query: 2147 IVTKDWLRDSFNRKVYLPEDAYLVQGITMSANHVLKNELREKNYQDKKSTNSQSGPGPIA 1968
            I+ + W      R+  L E++Y VQG + S+   +   L  ++ QDK   +S S    + 
Sbjct: 251  IIVRKWFDQCIARRACLNEESYPVQGGSASSKKSVSGSLSAQHSQDKFRASSVSATSLVV 310

Query: 1967 A---------------DSEATLXXXXXXXXXXXXXIMKGEEGIEAPPPSKIEDKEET-LD 1836
                            D EA               I + E+G EAP    ++   ET LD
Sbjct: 311  PEFNMSTVPSTGLGDPDLEAAHSQNTPSVLSDAQAIFE-EDGGEAP---NLQPSTETKLD 366

Query: 1835 SCVADDSQSEDSGLYLSDCRILLVGFHAAEMRKLVNKVRRGGGSRYMAFNDRLTHIVVGT 1656
             CVA+DSQSED+ LYLSDC+I LVGF A+EMRKLV  VRRGG SRYM+ N++LTHIVVG 
Sbjct: 367  GCVANDSQSEDNDLYLSDCKISLVGFEASEMRKLVTMVRRGGASRYMSCNEKLTHIVVGA 426

Query: 1655 PTENERRELRRYTAAGVIYVVRAVWLDDCDREKKELPVSKRHVVPDLILPKDS------- 1497
            P+E E++E+R   A+GVI+VV+  WL+DCDR+KKE+PV +RHV   L+LPKDS       
Sbjct: 427  PSELEKKEVRSIAASGVIHVVKTSWLEDCDRQKKEIPVHQRHVAYGLLLPKDSAHSVRGA 486

Query: 1496 -------------VCPDKATKIGTRQGHNLITPPSVPDHLTQCFRPSMPREQTEERKTME 1356
                         V  +  T + +  G +L   P +  +   C + ++   +     T+ 
Sbjct: 487  VTGIINSNQSKSSVPTNSGTGMPSSFGKSLDDKPKINMNGGSCLKATVGSSKQGLLPTIN 546

Query: 1355 AS-----KQESSMVKKN-----SSNIXXXXXXXXXXXFPLDRRAEIVEWIKQGGGEIVDG 1206
            ++     KQ+   V +N     SS +           FP DRRAEIVEW+ QGGG++V+ 
Sbjct: 547  STSNFWQKQQYDSVVQNPKNGISSAVFKGKTFCFSVSFPEDRRAEIVEWVDQGGGQVVED 606

Query: 1205 QSEFNVNFTVECHGLVTKAGNVSQSQTTIVSTHWIRSCLEDACMPDVGSHIIYSPVPCKI 1026
            Q + NVNF +ECHG++     ++ SQ T VSTHW+RSCLED C+ DVG HI+YSP+PC+I
Sbjct: 607  QVKKNVNFIIECHGVIPSC--ITDSQITYVSTHWVRSCLEDGCLLDVGRHILYSPLPCQI 664

Query: 1025 PLPGFEAFRFCVSQYEEKDRLLLRNLCFVLGAKFTEKLSKKVTHLLCKFTNGPKYEAACK 846
            P PGF+ FRFCVSQYEEKDRLLLRNLCF+LGAKF EKL+KKVTHLLCKFT+GPKYEAACK
Sbjct: 665  PFPGFKNFRFCVSQYEEKDRLLLRNLCFILGAKFVEKLTKKVTHLLCKFTSGPKYEAACK 724

Query: 845  WGMQTVTSEWISECIRQNAVVSAHPFRPKEMTAQDREAGLATMSQYTTQAARMISGEDVP 666
            WG+Q+VTSEWI EC+RQN VVS  PF PKE+TAQD+EAGL T+SQ+ TQAA+MI+  DVP
Sbjct: 725  WGIQSVTSEWIYECVRQNKVVSLDPFCPKEVTAQDQEAGLCTVSQFPTQAAKMIA-VDVP 783

Query: 665  SQSQGQSQ------FAMNSSRTFGKKSTNLSVEAEYPSATNKKRAKVSANNDKIDLLPLD 504
            SQ   Q Q        +      G ++     EAE  S  + KRA+   ++D+ DLL   
Sbjct: 784  SQFTSQPQGLRTQDLGVKMGSITGDRNDGSRDEAE-QSNDHFKRARHLEDDDQNDLL--- 839

Query: 503  VCANVSSCTMKSIKTSEGGN-IRDDG--SHDVPDVAAAIEDLLEESSKIQDMALSGRTIS 333
              + V  C     + S G N +++ G  +  +PDV   I DLLE++SKI D     R   
Sbjct: 840  -VSRVHLCEPFLNENSTGNNKLKNAGEAAQVLPDVDTVI-DLLEQTSKIHDQKSPERNGC 897

Query: 332  DRSIFSPDHSIITQNPATSHSAIQISTSWLSRKEKQD 222
            DRSIF  D + + Q+    HS I +S  WL+RK  Q+
Sbjct: 898  DRSIFLSDCTGLRQDHTDPHSVIGLSRHWLNRKLNQE 934


>ref|XP_009788829.1| PREDICTED: DNA topoisomerase 2-binding protein 1 isoform X3
            [Nicotiana sylvestris]
          Length = 985

 Score =  779 bits (2012), Expect = 0.0
 Identities = 437/938 (46%), Positives = 572/938 (60%), Gaps = 63/938 (6%)
 Frame = -1

Query: 2687 KGCKLLGTELVISCGKENRALPKNKGFTCCLAMDGVKVLATGFDNKEKGKIEKLVTAMGG 2508
            KGC L+          E R LP+ +GFTCCLAMDGVK+LA+GF+  EK ++ KLV+AMGG
Sbjct: 69   KGCNLI----------EQRPLPQ-QGFTCCLAMDGVKILASGFEMDEKVELGKLVSAMGG 117

Query: 2507 VFQTRAALDTDFVICKNVLSGKYKWGLQTLKKPVITINWLYQCWSEHRLVPHEPCRVLPF 2328
            V  T+A+LD  FVI KNVL+ KYKW +  LKKP++TINWL QCW EHRLVP E  +VLPF
Sbjct: 118  VLHTKASLDVSFVIVKNVLAAKYKWAVNKLKKPIVTINWLQQCWKEHRLVPQESFKVLPF 177

Query: 2327 SGLTICFTRIAADVRKEMENLIVHNGGQYSGDLTRNCTHLISDAPEGDKYRVAQKWGHVR 2148
            SGLTIC TRI  D R+EME +I+ NGG+YS +LTR C+HLI +APEG+KY+VA++WGH+ 
Sbjct: 178  SGLTICVTRIPIDERREMEKIILQNGGKYSPELTRKCSHLICNAPEGEKYKVAKRWGHIH 237

Query: 2147 IVTKDWLRDSFNRKVYLPEDAYLVQG--------ITMSANHVLKNELREKNYQDKKSTNS 1992
             VTK W   S  R+  L E++Y VQ         + M+  H L+  +R  N Q   S  +
Sbjct: 238  TVTKRWFDQSVARRACLDEESYPVQAGSPNTMTTLRMTNQHSLEKGMR--NLQGLSSLAT 295

Query: 1991 QSGPGPI----AADS--EATLXXXXXXXXXXXXXIM------KGEEGIEAPPPSK----- 1863
             S   P+    A+DS  EATL              +        +    AP  +K     
Sbjct: 296  PSNAEPVLCSGASDSYVEATLSQDMPDTPVLTKKEVNLAPAENPKSDYSAPVSTKNEQSG 355

Query: 1862 --IEDKEETLDSCVADDSQSEDSGLYLSDCRILLVGFHAAEMRKLVNKVRRGGGSRYMAF 1689
              IE ++   D  VADD+Q++D+  YL+DCRIL+VGF+A+EMRKLVN VR+GGGSRYM+F
Sbjct: 356  APIEQEQNDCDGGVADDTQADDNDFYLADCRILIVGFNASEMRKLVNLVRKGGGSRYMSF 415

Query: 1688 NDRLTHIVVGTPTE-----NERRELRRYTAAGVIYVVRAVWLDDCDREKKELPVSKRHVV 1524
             ++LTHI+ G P+E     +E +ELR   A GV++VV++ WL DCDREKKE+PV ++H+ 
Sbjct: 416  GEKLTHIIAGNPSEKLLSCSEIKELRNLAALGVVHVVKSEWLQDCDREKKEVPVLRKHIA 475

Query: 1523 PDLILPKDSVCPDKATKIGT---RQGHNLITPPSVPDHL-----TQCFRPSMPREQTEER 1368
             DL+LPKD +         T   RQG +     S  +H      + C  PS   ++ E  
Sbjct: 476  YDLLLPKDPIHCSNGAGTSTSMKRQGKSYGHTISSDEHAWRGTDSGCAMPSDKNKELENM 535

Query: 1367 KTMEASKQESSMVK----------------------KNSSNIXXXXXXXXXXXFPLDRRA 1254
              +  S +E+ +                        +  S++           FP+DRRA
Sbjct: 536  NDIRTSLRENGVQHQPYSSHHKDEKLLNESGCAVNGRKPSSVFEGRRFCFSASFPVDRRA 595

Query: 1253 EIVEWIKQGGGEIVDGQSEFNVNFTVECHGLVTKAGNVSQSQTTIVSTHWIRSCLEDACM 1074
            EIVEW+ QGGG +V+ Q+E NV+FTVECHG  T       +  T VS+HWI+SCLED C+
Sbjct: 596  EIVEWVSQGGGVVVEDQTETNVHFTVECHG--TLCSEKDGAAATFVSSHWIKSCLEDGCL 653

Query: 1073 PDVGSHIIYSPVPCKIPLPGFEAFRFCVSQYEEKDRLLLRNLCFVLGAKFTEKLSKKVTH 894
             DVGSHI+YSP+PC++P P F++FRFCVSQY+EK+R LLRNLCF +GAKF EKL+K+VTH
Sbjct: 654  LDVGSHILYSPLPCRVPFPAFQSFRFCVSQYDEKERQLLRNLCFTIGAKFAEKLTKRVTH 713

Query: 893  LLCKFTNGPKYEAACKWGMQTVTSEWISECIRQNAVVSAHPFRPKEMTAQDREAGLATMS 714
            LLCKF +GPKYE ACKWG+Q VT EWI ECI+ N +VS  PF PKE+T++DREAG+ T S
Sbjct: 714  LLCKFISGPKYEVACKWGIQPVTCEWIYECIKLNKIVSPDPFYPKEVTSEDREAGVCTTS 773

Query: 713  QYTTQAARMISGEDVPSQSQGQSQFAMN-SSRTFGKKSTNLSVEAEYPSATNKKRAKVSA 537
            Q+ TQA RM SG D  SQ Q Q Q  +N  +  F  +S     E ++ S  NKK   +  
Sbjct: 774  QFPTQAVRMTSG-DTSSQPQSQPQELINLRTEAFAGRSI-AKEEMKHSSRWNKKARLMVV 831

Query: 536  NNDKIDLLPLDVCANVSSCTMKSIKTSEGGNIRDDGSHDVPDVAAAIEDLLEESSKIQDM 357
                  L  +    N    T    K   G     +GS  VPDVAAAIEDLLE++SKI D 
Sbjct: 832  EETNCSLTCVSNENNAFCGTNPPEKNMIGST--KEGSSAVPDVAAAIEDLLEQTSKIHDQ 889

Query: 356  ALSGRTISDRSIFSPDHSIITQNPATSHSAIQISTSWLSRKEKQDDGNQCDSSSVQGVNE 177
                R   D+ +F+   +I+ Q     H+ + +S  W +R EK+DD +     +   V  
Sbjct: 890  KSPSRIECDKELFTSGCNILAQGHEDHHTTLGLSNDWTNRFEKKDDSHGHSGDATANV-- 947

Query: 176  HRTYDGFSETQTESQVVVYEEDLSGRQMMIDRHRTRSS 63
               YD FSETQT+SQVV Y EDLSGRQM+IDR RTRSS
Sbjct: 948  ---YDHFSETQTDSQVVGYAEDLSGRQMIIDRVRTRSS 982


>ref|XP_011091797.1| PREDICTED: DNA topoisomerase 2-binding protein 1-A isoform X2
            [Sesamum indicum]
          Length = 937

 Score =  778 bits (2009), Expect = 0.0
 Identities = 427/886 (48%), Positives = 554/886 (62%), Gaps = 10/886 (1%)
 Frame = -1

Query: 2687 KGCKLLGTELVISCGKENRALPKNKGFTCCLAMDGVKVLATGFDNKEKGKIEKLVTAMGG 2508
            KGCKL+G + V+SC KE+R LP N+GFTCCLAMDGV +LA+GF+  EK +I K+VTAMGG
Sbjct: 68   KGCKLIGPQCVLSCAKEHRVLP-NQGFTCCLAMDGVNILASGFEKDEKAEIAKMVTAMGG 126

Query: 2507 VFQTRAALDTDFVICKNVLSGKYKWGLQTLKKPVITINWLYQCWSEHRLVPHEPCRVLPF 2328
            V  T+A+ D  FVI KNVL+ KYKW L  LKKP++T NWL QCW EHR+VP +  RVLPF
Sbjct: 127  VLVTKASSDVSFVIVKNVLAQKYKWALNNLKKPIVTTNWLLQCWKEHRVVPQDCYRVLPF 186

Query: 2327 SGLTICFTRIAADVRKEMENLIVHNGGQYSGDLTRNCTHLISDAPEGDKYRVAQKWGHVR 2148
            SGLTIC + I AD RKEME L++ NGG+YS +LT+ CTHL+ DAPEGDKY+VA++WGH+ 
Sbjct: 187  SGLTICVSGIPADERKEMEKLVMQNGGKYSAELTKRCTHLVCDAPEGDKYKVAKRWGHIY 246

Query: 2147 IVTKDWLRDSFNRKVYLPEDAYLVQGITMSANHVLKNELREKNYQDKKSTNSQ--SGPGP 1974
            IVT+ W   S  R+  L E++Y VQG T+S+   LK    E++ Q K   NSQ  S    
Sbjct: 247  IVTRKWFHQSVARRACLSEESYPVQGSTISSLSTLKTV--EQHSQGKVIRNSQHTSSSMA 304

Query: 1973 IAADSEATLXXXXXXXXXXXXXIMKGEEGIEAP--------PPSKIEDKEETLDSCVADD 1818
             A+DSE                        EAP        PP+ ++  +     C+ADD
Sbjct: 305  TASDSETNFSAQDMGPDFENPLPNIYPAFFEAPSLPKEDNDPPADMQKNDPNFARCIADD 364

Query: 1817 SQSEDSGLYLSDCRILLVGFHAAEMRKLVNKVRRGGGSRYMAFNDRLTHIVVGTPTENER 1638
            SQSED  LYLS+CRILLVGF A+E+RKLV+ VRRGGGSRYM+F+++LTH++VG P+E E 
Sbjct: 365  SQSEDDDLYLSECRILLVGFEASELRKLVDMVRRGGGSRYMSFSEKLTHVIVGKPSELEI 424

Query: 1637 RELRRYTAAGVIYVVRAVWLDDCDREKKELPVSKRHVVPDLILPKDSVCPDKATKIGTRQ 1458
            +E+R   A GVIYVV+  WL++C  +KKE+PV K H+  DL+LPKD V  +KAT      
Sbjct: 425  KEVRSVAAFGVIYVVKTAWLEECTFKKKEVPVLKSHIAYDLLLPKDPVIFNKATATNMNS 484

Query: 1457 GHNLITPPSVPDHLTQCFRPSMPREQTEERKTMEASKQESSMVKKNSSNIXXXXXXXXXX 1278
               + +  S P         S   E   E    +     S+     SS +          
Sbjct: 485  AKQMKSSASQPMDDNILENKSSQCEVVIEEAKPKVQSGVSNGKHMKSSAVFKGKLFGFSS 544

Query: 1277 XFPLDRRAEIVEWIKQGGGEIVDGQSEFNVNFTVECHGLVTKAGNVSQSQTTIVSTHWIR 1098
             FP ++R EIV W+ +GGGE++  Q   NV+FTVE HG+          ++T V+THWI 
Sbjct: 545  TFPEEQRPEIVLWVHEGGGEVIVDQQVNNVHFTVERHGVPHLTHTF---RSTYVTTHWIH 601

Query: 1097 SCLEDACMPDVGSHIIYSPVPCKIPLPGFEAFRFCVSQYEEKDRLLLRNLCFVLGAKFTE 918
            SCL+D C+ DV SHI+YSP+ C+IPLPGFE FR CVS+Y+ ++R LLRNLC+VLG KF E
Sbjct: 602  SCLQDGCLLDVSSHILYSPLTCQIPLPGFEGFRLCVSRYDMRERQLLRNLCYVLGVKFVE 661

Query: 917  KLSKKVTHLLCKFTNGPKYEAACKWGMQTVTSEWISECIRQNAVVSAHPFRPKEMTAQDR 738
            KL+KKVTHLLCKF +G K+EAAC+WG+  VT+EWI EC  +N VV    F PKE+T+QDR
Sbjct: 662  KLTKKVTHLLCKFADGDKFEAACRWGIHVVTAEWIYECAMKNKVVDLKGFYPKELTSQDR 721

Query: 737  EAGLATMSQYTTQAARMISGEDVPSQSQGQSQFAMNSSRTFGKKSTNLSVEAEYPSATNK 558
            EAGL  +SQY TQ+ RM SG+D  SQ   Q Q   N  R     +  ++   +  S+   
Sbjct: 722  EAGLYFVSQYPTQSVRMTSGDDA-SQCLSQLQDQSNMQRV--ASTGCMARYKDNDSSNGS 778

Query: 557  KRAKVSANNDKIDLLPLDVCANVSSCTMKSIKTSEGGNIRDDGSHDVPDVAAAIEDLLEE 378
            KRA++   ND I   PL   +   +   +   T             VPDVAAAIEDLLE+
Sbjct: 779  KRARL-LGNDSIK-HPLSFVSAADNSVNRKNPTENNVTECTREPSVVPDVAAAIEDLLEQ 836

Query: 377  SSKIQDMALSGRTISDRSIFSPDHSIITQNPATSHSAIQISTSWLSRKEKQDDGNQCDSS 198
            +SKIQD      +    +  S + +++ Q  A   S    S  W++R EK+DD    D++
Sbjct: 837  TSKIQDRKSQETSGCHENFLSSNSTMLGQRHADGQSDPGPSKHWMNRLEKRDDNPSADAA 896

Query: 197  SVQGVNEHRTYDGFSETQTESQVVVYEEDLSGRQMMIDRHRTRSSM 60
            +         YDGFSETQT+SQVV YEEDLSGRQM+IDR RTRSSM
Sbjct: 897  A------RGFYDGFSETQTDSQVVGYEEDLSGRQMIIDRVRTRSSM 936