BLASTX 2.2.25 [Feb-01-2011]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= Papaver27_contig00016933
         (1826 letters)

Database: ./nr 
           38,876,450 sequences; 13,856,398,315 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gb|AFB74615.1| cytochrome P450 [Papaver somniferum]                   965   0.0  
gb|AFI57927.1| cytochrome P450, partial [Papaver somniferum]          957   0.0  
gb|ADB89214.1| stylopine synthase [Papaver somniferum]                749   0.0  
sp|B1NF19.1|C719D_ARGME RecName: Full=(S)-stylopine synthase; Sh...   741   0.0  
gb|AHF65153.1| stylopine synthase, partial [synthetic construct]      734   0.0  
sp|Q50LH3.1|C7192_ESCCA RecName: Full=(S)-stylopine synthase 1; ...   712   0.0  
gb|ACO90219.1| stylopine synthase [Eschscholzia californica]          707   0.0  
dbj|BAG75116.1| cytochrome P450 [Eschscholzia californica]            704   0.0  
sp|Q50LH4.1|C7193_ESCCA RecName: Full=(S)-stylopine synthase 2; ...   701   0.0  
dbj|BAG75114.1| cytochrome P450 [Eschscholzia californica]            686   0.0  
dbj|BAG75115.1| cytochrome P450 [Eschscholzia californica]            660   0.0  
gb|AAU20771.1| (S)-canadine synthase [Thalictrum flavum subsp. g...   631   e-178
gb|AGL76711.1| (S)-canadine synthase, partial [Coptis chinensis]      627   e-177
sp|Q948Y1.1|C719A_COPJA RecName: Full=(S)-canadine synthase; Alt...   621   e-175
sp|B5UAQ8.1|C7195_ESCCA RecName: Full=Cheilanthifoline synthase;...   597   e-168
sp|B1NF20.1|C719E_ARGME RecName: Full=Cheilanthifoline synthase;...   589   e-165
gb|ADB89213.1| cheilanthifoline synthase [Papaver somniferum]         588   e-165
dbj|BAF98470.1| cytochrome P450 [Coptis japonica var. dissecta]       561   e-157
dbj|BAF98471.1| cytochrome P450 [Coptis japonica var. dissecta]       541   e-151
gb|AGC29954.1| CYP719A24 [Podophyllum peltatum]                       538   e-150

>gb|AFB74615.1| cytochrome P450 [Papaver somniferum]
          Length = 486

 Score =  965 bits (2495), Expect = 0.0
 Identities = 486/486 (100%), Positives = 486/486 (100%)
 Frame = +1

Query: 184  MIMSNLWILTLISTILAVFAAVLIIFRRRISASTTEWPVGPKTLPIIGNLHILGGTALHV 363
            MIMSNLWILTLISTILAVFAAVLIIFRRRISASTTEWPVGPKTLPIIGNLHILGGTALHV
Sbjct: 1    MIMSNLWILTLISTILAVFAAVLIIFRRRISASTTEWPVGPKTLPIIGNLHILGGTALHV 60

Query: 364  VLHKLAEVYGSVMTIWIGSWKPVIIVSDFDRAWEVLVNKSSDYSAREMPEITKIGTANWR 543
            VLHKLAEVYGSVMTIWIGSWKPVIIVSDFDRAWEVLVNKSSDYSAREMPEITKIGTANWR
Sbjct: 61   VLHKLAEVYGSVMTIWIGSWKPVIIVSDFDRAWEVLVNKSSDYSAREMPEITKIGTANWR 120

Query: 544  TISSSDSGPFWATLRKGLQSVALSPQHLASQTAHQERDIIKLIKNLKDEAASGMVKPLDH 723
            TISSSDSGPFWATLRKGLQSVALSPQHLASQTAHQERDIIKLIKNLKDEAASGMVKPLDH
Sbjct: 121  TISSSDSGPFWATLRKGLQSVALSPQHLASQTAHQERDIIKLIKNLKDEAASGMVKPLDH 180

Query: 724  LKKATVRLISRLIYGQDFDDDKYVEDMHDVIEFLIRISGYAQLAEVFYYAKYLPGHKRAV 903
            LKKATVRLISRLIYGQDFDDDKYVEDMHDVIEFLIRISGYAQLAEVFYYAKYLPGHKRAV
Sbjct: 181  LKKATVRLISRLIYGQDFDDDKYVEDMHDVIEFLIRISGYAQLAEVFYYAKYLPGHKRAV 240

Query: 904  TGAEEAKRRVIALVRPFLQSNPATNTYLHFLKSQLYPEEVIIFAIFEAYLLGVDSTSSTT 1083
            TGAEEAKRRVIALVRPFLQSNPATNTYLHFLKSQLYPEEVIIFAIFEAYLLGVDSTSSTT
Sbjct: 241  TGAEEAKRRVIALVRPFLQSNPATNTYLHFLKSQLYPEEVIIFAIFEAYLLGVDSTSSTT 300

Query: 1084 AWALAFLIREPSVQEKLYQELKNFTANNNRTMLKVEDVNKLPYLQAVVKETMRMKPIAPL 1263
            AWALAFLIREPSVQEKLYQELKNFTANNNRTMLKVEDVNKLPYLQAVVKETMRMKPIAPL
Sbjct: 301  AWALAFLIREPSVQEKLYQELKNFTANNNRTMLKVEDVNKLPYLQAVVKETMRMKPIAPL 360

Query: 1264 AIPHKACKDTSLMGKKVDKGTKVMVNIHALHHTEKVWKEPYKFIPERFLQKHDKAMEQSL 1443
            AIPHKACKDTSLMGKKVDKGTKVMVNIHALHHTEKVWKEPYKFIPERFLQKHDKAMEQSL
Sbjct: 361  AIPHKACKDTSLMGKKVDKGTKVMVNIHALHHTEKVWKEPYKFIPERFLQKHDKAMEQSL 420

Query: 1444 LPFSAGMRICAGMELGKLQFSFSLANLVNAFKWSCVSDGVLPDMSDLLGFVLFMKTPLEA 1623
            LPFSAGMRICAGMELGKLQFSFSLANLVNAFKWSCVSDGVLPDMSDLLGFVLFMKTPLEA
Sbjct: 421  LPFSAGMRICAGMELGKLQFSFSLANLVNAFKWSCVSDGVLPDMSDLLGFVLFMKTPLEA 480

Query: 1624 RIVPRL 1641
            RIVPRL
Sbjct: 481  RIVPRL 486


>gb|AFI57927.1| cytochrome P450, partial [Papaver somniferum]
          Length = 488

 Score =  957 bits (2473), Expect = 0.0
 Identities = 484/488 (99%), Positives = 485/488 (99%), Gaps = 2/488 (0%)
 Frame = +1

Query: 184  MIMSNLWILTLISTILAVFAAVLIIFRRRISASTTEWPVGPKTLPIIGNLHILGGTALHV 363
            MIMSNLWILTLISTILAVFAAVLIIFRRRISASTTEWPVGPKTLPIIGNLHILGGTALHV
Sbjct: 1    MIMSNLWILTLISTILAVFAAVLIIFRRRISASTTEWPVGPKTLPIIGNLHILGGTALHV 60

Query: 364  VLHKLAEVYGSVMTIWIGSWKPVIIVSDFDRAWEVLVNKSSDYSAREMPEITKIGTANWR 543
            VLHKLAEVYGSVMTIWIGSWKPVIIVSDFDRAWEVLVNKSSDYSAREMPEITKIGTANWR
Sbjct: 61   VLHKLAEVYGSVMTIWIGSWKPVIIVSDFDRAWEVLVNKSSDYSAREMPEITKIGTANWR 120

Query: 544  TISSSDSGPFWATLRKGLQSVALSPQHLASQTAHQERDIIKLIKNLKDEAA--SGMVKPL 717
            TISSSDSGPFWATLRKGLQSVALSPQHLASQTAHQERDIIKLIKNLKDEAA  SGMVKPL
Sbjct: 121  TISSSDSGPFWATLRKGLQSVALSPQHLASQTAHQERDIIKLIKNLKDEAALNSGMVKPL 180

Query: 718  DHLKKATVRLISRLIYGQDFDDDKYVEDMHDVIEFLIRISGYAQLAEVFYYAKYLPGHKR 897
            DHLKKATVRLISRLIYGQDFDDDKYVEDMHDVIEFLIRISGYAQLAEVFYYAKYLP HKR
Sbjct: 181  DHLKKATVRLISRLIYGQDFDDDKYVEDMHDVIEFLIRISGYAQLAEVFYYAKYLPSHKR 240

Query: 898  AVTGAEEAKRRVIALVRPFLQSNPATNTYLHFLKSQLYPEEVIIFAIFEAYLLGVDSTSS 1077
            AVTGAEEAKRRVIALVRPFLQSNPATNTYLHFLKSQLYPEEVIIFAIFEAYLLGVDSTSS
Sbjct: 241  AVTGAEEAKRRVIALVRPFLQSNPATNTYLHFLKSQLYPEEVIIFAIFEAYLLGVDSTSS 300

Query: 1078 TTAWALAFLIREPSVQEKLYQELKNFTANNNRTMLKVEDVNKLPYLQAVVKETMRMKPIA 1257
            TTAWALAFLIREPSVQEKLYQELKNFTANNNRTMLKVEDVNKLPYLQAVVKETMRMKPIA
Sbjct: 301  TTAWALAFLIREPSVQEKLYQELKNFTANNNRTMLKVEDVNKLPYLQAVVKETMRMKPIA 360

Query: 1258 PLAIPHKACKDTSLMGKKVDKGTKVMVNIHALHHTEKVWKEPYKFIPERFLQKHDKAMEQ 1437
            PLAIPHKACKDTSLMGKKVDKGTKVMVNIHALHHTEKVWKEPYKF+PERFLQKHDKAMEQ
Sbjct: 361  PLAIPHKACKDTSLMGKKVDKGTKVMVNIHALHHTEKVWKEPYKFMPERFLQKHDKAMEQ 420

Query: 1438 SLLPFSAGMRICAGMELGKLQFSFSLANLVNAFKWSCVSDGVLPDMSDLLGFVLFMKTPL 1617
            SLLPFSAGMRICAGMELGKLQFSFSLANLVNAFKWSCVSDGVLPDMSDLLGFVLFMKTPL
Sbjct: 421  SLLPFSAGMRICAGMELGKLQFSFSLANLVNAFKWSCVSDGVLPDMSDLLGFVLFMKTPL 480

Query: 1618 EARIVPRL 1641
            EARIVPRL
Sbjct: 481  EARIVPRL 488


>gb|ADB89214.1| stylopine synthase [Papaver somniferum]
          Length = 494

 Score =  749 bits (1934), Expect = 0.0
 Identities = 373/495 (75%), Positives = 430/495 (86%), Gaps = 6/495 (1%)
 Frame = +1

Query: 175  IKEMIMSNLWILTLISTILAVFAAVLIIFRRRISASTTEWPVGPKTLPIIGNLHILGGTA 354
            +++ I SN WILT  + ++     +L++F+R+ S ST  WP GPKTLPIIGN+H+LGGTA
Sbjct: 1    MEKTIFSNPWILTTSTLVVITIITMLMVFKRKKS-STMVWPTGPKTLPIIGNMHVLGGTA 59

Query: 355  LHVVLHKLAEVYGSVMTIWIGSWKPVIIVSDFDRAWEVLVNKSSDYSAREMPEITKIGTA 534
            L VVLH LA+++G+VMTIWIGSW+PVI+VSD DRAWEVLVNKSSDYSAR+MPEITKI +A
Sbjct: 60   LQVVLHNLAKIHGNVMTIWIGSWRPVIVVSDIDRAWEVLVNKSSDYSARDMPEITKIISA 119

Query: 535  NWRTISSSDSGPFWATLRKGLQSVALSPQHLASQTAHQERDIIKLIKNLKDEAAS--GMV 708
            +W+TIS+SDSGP W+ LRKGLQ+VALSP +LA+Q+  QE+DI K+I++LK EAAS  G+V
Sbjct: 120  DWKTISTSDSGPGWSNLRKGLQNVALSPHNLAAQSQFQEKDITKMIQSLKKEAASNNGIV 179

Query: 709  KPLDHLKKATVRLISRLIYGQDFDDDKYVEDMHDVIEFLIRISGYAQLAEVFYYAKYLPG 888
            KP+DHLKKAT+RLISRLI+GQDFDDDKYV+DMH  IE LIR+SGYAQLAE FYYAKYLP 
Sbjct: 180  KPIDHLKKATLRLISRLIFGQDFDDDKYVDDMHHAIEELIRVSGYAQLAEAFYYAKYLPS 239

Query: 889  HKRAVTGAEEAKRRVIALVRPFLQSNPATNTYLHFLKSQLYPEEVIIFAIFEAYLLGVDS 1068
            HK+AV   EEA +RV  LVRPFL  NP TNTYLHFL SQ Y EEVIIFAIFEAYLLGVDS
Sbjct: 240  HKKAVRDVEEANQRVKKLVRPFLSLNPPTNTYLHFLNSQKYDEEVIIFAIFEAYLLGVDS 299

Query: 1069 TSSTTAWALAFLIREPSVQEKLYQELKNFTANNNRTMLKVEDVNKLPYLQAVVKETMRMK 1248
            TS TTAWALAFLIREP VQ+KLYQELKN TA N+  ++KVED+NKL YLQAV+KETMRMK
Sbjct: 300  TSLTTAWALAFLIREPVVQDKLYQELKNLTAKNDCEIVKVEDLNKLQYLQAVLKETMRMK 359

Query: 1249 PIAPLAIPHKACKDTSLMGKKVDKGTKVMVNIHALHHTEKVWKEPYKFIPERFLQKHD-- 1422
            PIAPLAIPHKAC+DTSL G K+D+GT+VMVNI+ALHH EKVWKEP+KF+PERFLQ  D  
Sbjct: 360  PIAPLAIPHKACRDTSLKGNKIDQGTQVMVNIYALHHNEKVWKEPFKFMPERFLQTQDVV 419

Query: 1423 --KAMEQSLLPFSAGMRICAGMELGKLQFSFSLANLVNAFKWSCVSDGVLPDMSDLLGFV 1596
              K MEQSLLPFSAGMRICAGMELGKLQFSFSLANLVNAF+WSCVSDGVLPDMSD LGFV
Sbjct: 420  NGKGMEQSLLPFSAGMRICAGMELGKLQFSFSLANLVNAFEWSCVSDGVLPDMSDQLGFV 479

Query: 1597 LFMKTPLEARIVPRL 1641
            L MKTPL+ARIVPR+
Sbjct: 480  LLMKTPLQARIVPRV 494


>sp|B1NF19.1|C719D_ARGME RecName: Full=(S)-stylopine synthase; Short=STS; AltName:
            Full=Cytochrome P450 719A13 gi|148841092|gb|ABR14721.1|
            stylopine synthase [Argemone mexicana]
          Length = 504

 Score =  741 bits (1914), Expect = 0.0
 Identities = 377/504 (74%), Positives = 433/504 (85%), Gaps = 15/504 (2%)
 Frame = +1

Query: 175  IKEMIMSNL--WILTLIST-----ILAVFAAVLIIFRR-RISASTTEWPVGPKTLPIIGN 330
            ++E IM+N   WILT  +T     +L++   + II RR + S+S   WP GPKTLPIIGN
Sbjct: 1    MEEKIMTNNSPWILTSSTTTTTTILLSLLFTIFIILRRNKSSSSKMVWPTGPKTLPIIGN 60

Query: 331  LHILGGTALHVVLHKLAEVYGSVMTIWIGSWKPVIIVSDFDRAWEVLVNKSSDYSAREMP 510
            ++ILGGTALHVVLH LA+ YG+VMTIWIGSW+PVI+VSD DRAWEVLVNKSSDYSAR+MP
Sbjct: 61   MNILGGTALHVVLHNLAKTYGNVMTIWIGSWRPVIVVSDIDRAWEVLVNKSSDYSARDMP 120

Query: 511  EITKIGTANWRTISSSDSGPFWATLRKGLQSVALSPQHLASQTAHQERDIIKLIKNLKDE 690
            EITK+ TA+W+TISSSDSGPFW  LRKGLQ+VALSPQ+L+SQ+  QERDIIK I+NLK+E
Sbjct: 121  EITKLATADWKTISSSDSGPFWTNLRKGLQNVALSPQNLSSQSKFQERDIIKTIQNLKEE 180

Query: 691  AA--SGMVKPLDHLKKATVRLISRLIYGQDFDDDKYVEDMHDVIEFLIRISGYAQLAEVF 864
            A   +G+VKPLDHLKKA VRLISRLIYGQDFD+D+YVE+MH  IE LIR+SGYA+LAE F
Sbjct: 181  AKMNNGIVKPLDHLKKAMVRLISRLIYGQDFDNDEYVEEMHHTIEELIRVSGYARLAEAF 240

Query: 865  YYAKYLPGHKRAVTGAEEAKRRVIALVRPFLQSNPATNTYLHFLKSQLYPEEVIIFAIFE 1044
            YYAKYLP HK+AV    +A +RV  LVRP L  N  TNTYLHFL+SQ Y +EVIIFAIFE
Sbjct: 241  YYAKYLPSHKKAVREVLQANQRVQNLVRPLLSLNSPTNTYLHFLRSQNYEDEVIIFAIFE 300

Query: 1045 AYLLGVDSTSSTTAWALAFLIREPSVQEKLYQELKNFTANNNRTMLKVEDVNKLPYLQAV 1224
            AYLLGVDSTSSTTAWALA+LIREP+VQEKLY+ELKNFT +N+R M+K ED+NKL YLQAV
Sbjct: 301  AYLLGVDSTSSTTAWALAYLIREPNVQEKLYEELKNFTNDNDRKMVKFEDLNKLQYLQAV 360

Query: 1225 VKETMRMKPIAPLAIPHKACKDTSLMGKKVDKGTKVMVNIHALHHTEKVWKEPYKFIPER 1404
            VKETMRMKPIAPLAIPHKAC++TSLMG+KV++GT+VMVNI+ALHH + VWKEPYKF PER
Sbjct: 361  VKETMRMKPIAPLAIPHKACRETSLMGRKVNQGTRVMVNIYALHHNQNVWKEPYKFNPER 420

Query: 1405 FLQKHD-----KAMEQSLLPFSAGMRICAGMELGKLQFSFSLANLVNAFKWSCVSDGVLP 1569
            FLQK+      KAMEQSLLPFSAGMRICAGMELGKLQFSF+LANLVNAFKWSCVSDGV P
Sbjct: 421  FLQKNQDGVDGKAMEQSLLPFSAGMRICAGMELGKLQFSFALANLVNAFKWSCVSDGVFP 480

Query: 1570 DMSDLLGFVLFMKTPLEARIVPRL 1641
            DMSD LGFVL MKTPLEA IVPR+
Sbjct: 481  DMSDQLGFVLLMKTPLEAGIVPRM 504


>gb|AHF65153.1| stylopine synthase, partial [synthetic construct]
          Length = 511

 Score =  734 bits (1895), Expect = 0.0
 Identities = 365/469 (77%), Positives = 413/469 (88%), Gaps = 6/469 (1%)
 Frame = +1

Query: 253  IIFRRRISASTTEWPVGPKTLPIIGNLHILGGTALHVVLHKLAEVYGSVMTIWIGSWKPV 432
            II  +R  +ST  WP GPKTLPIIGN+H+LGGTAL VVLH LA+++G+VMTIWIGSW+PV
Sbjct: 40   IIGHKRKKSSTMVWPTGPKTLPIIGNMHVLGGTALQVVLHNLAKIHGNVMTIWIGSWRPV 99

Query: 433  IIVSDFDRAWEVLVNKSSDYSAREMPEITKIGTANWRTISSSDSGPFWATLRKGLQSVAL 612
            I+VSD DRAWEVLVNKSSDYSAR+MPEITKI +A+W+TIS+SDSGP W+ LRKGLQ+VAL
Sbjct: 100  IVVSDIDRAWEVLVNKSSDYSARDMPEITKIISADWKTISTSDSGPGWSNLRKGLQNVAL 159

Query: 613  SPQHLASQTAHQERDIIKLIKNLKDEAAS--GMVKPLDHLKKATVRLISRLIYGQDFDDD 786
            SP +LA+Q+  QE+DI K+I++LK EAAS  G+VKP+DHLKKAT+RLISRLI+GQDFDDD
Sbjct: 160  SPHNLAAQSQFQEKDITKMIQSLKKEAASNNGIVKPIDHLKKATLRLISRLIFGQDFDDD 219

Query: 787  KYVEDMHDVIEFLIRISGYAQLAEVFYYAKYLPGHKRAVTGAEEAKRRVIALVRPFLQSN 966
            KYV+DMH  IE LIR+SGYAQLAE FYYAKYLP HK+AV   EEA +RV  LVRPFL  N
Sbjct: 220  KYVDDMHHAIEELIRVSGYAQLAEAFYYAKYLPSHKKAVRDVEEANQRVKKLVRPFLSLN 279

Query: 967  PATNTYLHFLKSQLYPEEVIIFAIFEAYLLGVDSTSSTTAWALAFLIREPSVQEKLYQEL 1146
            P TNTYLHFL SQ Y EEVIIFAIFEAYLLGVDSTS TTAWALAFLIREP VQ+KLYQEL
Sbjct: 280  PPTNTYLHFLNSQKYDEEVIIFAIFEAYLLGVDSTSLTTAWALAFLIREPVVQDKLYQEL 339

Query: 1147 KNFTANNNRTMLKVEDVNKLPYLQAVVKETMRMKPIAPLAIPHKACKDTSLMGKKVDKGT 1326
            KN TA N+  ++KVED+NKL YLQAV+KETMRMKPIAPLAIPHKAC+DTSL G K+D+GT
Sbjct: 340  KNLTAKNDCEIVKVEDLNKLQYLQAVLKETMRMKPIAPLAIPHKACRDTSLKGNKIDQGT 399

Query: 1327 KVMVNIHALHHTEKVWKEPYKFIPERFLQKHD----KAMEQSLLPFSAGMRICAGMELGK 1494
            +VMVNI+ALHH EKVWKEP+KF+PERFLQ  D    K MEQSLLPFSAGMRICAGMELGK
Sbjct: 400  QVMVNIYALHHNEKVWKEPFKFMPERFLQTQDVVNGKGMEQSLLPFSAGMRICAGMELGK 459

Query: 1495 LQFSFSLANLVNAFKWSCVSDGVLPDMSDLLGFVLFMKTPLEARIVPRL 1641
            LQFSFSLANLVNAF+WSCVSDGVLPDMSD LGFVL MKTPL+ARIVPR+
Sbjct: 460  LQFSFSLANLVNAFEWSCVSDGVLPDMSDQLGFVLLMKTPLQARIVPRV 508


>sp|Q50LH3.1|C7192_ESCCA RecName: Full=(S)-stylopine synthase 1; Short=STS; AltName:
            Full=Cytochrome P450 719A2; Short=EcCYP719A2;
            Short=EcCYPB gi|63108256|dbj|BAD98250.1| stylopine
            synthase [Eschscholzia californica]
          Length = 495

 Score =  712 bits (1838), Expect = 0.0
 Identities = 354/492 (71%), Positives = 423/492 (85%), Gaps = 7/492 (1%)
 Frame = +1

Query: 175  IKEMIMSNLWILTLISTILAVFAAVLIIFRRRISASTTEWPVGPKTLPIIGNLHILGGTA 354
            +K ++M+N WILT  +T L +  ++ + F R+  +S   WP GPKTLPIIGN+H+LGGTA
Sbjct: 4    MKILMMNNPWILTATATTLLI--SIFLFFTRK--SSKMVWPAGPKTLPIIGNMHLLGGTA 59

Query: 355  LHVVLHKLAEVYGSVMTIWIGSWKPVIIVSDFDRAWEVLVNKSSDYSAREMPEITKIGTA 534
            L VVLH LA+V+GSVMTIWIGSW+PVI+VSD +RAWEVLVNKSSDYSAR+MP+ITKI +A
Sbjct: 60   LQVVLHNLAKVHGSVMTIWIGSWRPVIVVSDIERAWEVLVNKSSDYSARDMPDITKIISA 119

Query: 535  NWRTISSSDSGPFWATLRKGLQSVALSPQHLASQTAHQERDIIKLIKNLKDEAAS--GMV 708
            +W+TIS+SDSGP W  LRKGLQ+VALSP +LA+Q   QE+D+ K+I+ L++EA +  G+V
Sbjct: 120  DWKTISTSDSGPHWTNLRKGLQNVALSPHNLAAQFQFQEKDMTKMIQTLEEEARNNNGIV 179

Query: 709  KPLDHLKKATVRLISRLIYGQDFDDDKYVEDMHDVIEFLIRISGYAQLAEVFYYAKYLPG 888
            KPLDH+KKAT+RLISRL++GQDF++DKYV+DMH  IE LIR+SGYA+LAE FYYAKYLP 
Sbjct: 180  KPLDHMKKATLRLISRLVFGQDFNNDKYVDDMHLAIEELIRVSGYARLAEAFYYAKYLPS 239

Query: 889  HKRAVTGAEEAKRRVIALVRPFLQSNPATNTYLHFLKSQLYPEEVIIFAIFEAYLLGVDS 1068
            HK+AV   EEA+RRV  LV PFL  NP TNTYLHFL+SQ Y +EVIIFAIFEAYLLGVDS
Sbjct: 240  HKKAVREVEEAQRRVQNLVSPFLSLNPPTNTYLHFLRSQKYDDEVIIFAIFEAYLLGVDS 299

Query: 1069 TSSTTAWALAFLIREPSVQEKLYQELKNFTANNNRTMLKVEDVNKLPYLQAVVKETMRMK 1248
            TS TTAWALAFLIREP+VQEKLYQEL++F + N+R +LKVED+NKL YLQAV+KETMRMK
Sbjct: 300  TSLTTAWALAFLIREPNVQEKLYQELESFASKNDRRILKVEDINKLQYLQAVIKETMRMK 359

Query: 1249 PIAPLAIPHKACKDTSLMGKKVDKGTKVMVNIHALHHTEKVWKEPYKFIPERFLQ----- 1413
            PIAPLAIPHKAC+DTSLMGKK+DKGT+VMVNI ALHH + V+ +P+KF+PERF++     
Sbjct: 360  PIAPLAIPHKACRDTSLMGKKIDKGTRVMVNIFALHHNKNVFNDPFKFMPERFMKVDSQD 419

Query: 1414 KHDKAMEQSLLPFSAGMRICAGMELGKLQFSFSLANLVNAFKWSCVSDGVLPDMSDLLGF 1593
             + KAMEQSLLPFSAGMRICAGMELGKLQFSF+LANL  AFKWSCV+DGVLPDMSD LGF
Sbjct: 420  ANGKAMEQSLLPFSAGMRICAGMELGKLQFSFALANLAYAFKWSCVADGVLPDMSDQLGF 479

Query: 1594 VLFMKTPLEARI 1629
            VL MKTPLEARI
Sbjct: 480  VLLMKTPLEARI 491


>gb|ACO90219.1| stylopine synthase [Eschscholzia californica]
          Length = 495

 Score =  707 bits (1825), Expect = 0.0
 Identities = 352/492 (71%), Positives = 422/492 (85%), Gaps = 7/492 (1%)
 Frame = +1

Query: 175  IKEMIMSNLWILTLISTILAVFAAVLIIFRRRISASTTEWPVGPKTLPIIGNLHILGGTA 354
            +K ++M+N WILT  +T L +  ++ + F R+  +S   WP GPKTLPIIGN+H+LGGTA
Sbjct: 4    MKILMMNNPWILTATATTLLI--SIFLFFTRK--SSKMVWPAGPKTLPIIGNMHLLGGTA 59

Query: 355  LHVVLHKLAEVYGSVMTIWIGSWKPVIIVSDFDRAWEVLVNKSSDYSAREMPEITKIGTA 534
            L VVLH LA+V+GSVMTIWIGSW+PVI+VSD +RAWEVLVNKSSDYSAR+MP+ITKI +A
Sbjct: 60   LQVVLHNLAKVHGSVMTIWIGSWRPVIVVSDIERAWEVLVNKSSDYSARDMPDITKIISA 119

Query: 535  NWRTISSSDSGPFWATLRKGLQSVALSPQHLASQTAHQERDIIKLIKNLKDEAAS--GMV 708
            +W+TIS+SDSGP W  LRKGLQ+VALSP +LA+Q   QE+D+ K+I+ L++EA +  G+V
Sbjct: 120  DWKTISTSDSGPHWTNLRKGLQNVALSPHNLAAQFQFQEKDMTKMIQTLQEEARNNNGIV 179

Query: 709  KPLDHLKKATVRLISRLIYGQDFDDDKYVEDMHDVIEFLIRISGYAQLAEVFYYAKYLPG 888
            KPLDH+KKAT+RLISRL++GQDF++DKYV+DMH  IE LIR+SGYA+LAE FYYAKYLP 
Sbjct: 180  KPLDHMKKATLRLISRLVFGQDFNNDKYVDDMHLAIEELIRVSGYARLAEAFYYAKYLPS 239

Query: 889  HKRAVTGAEEAKRRVIALVRPFLQSNPATNTYLHFLKSQLYPEEVIIFAIFEAYLLGVDS 1068
            HK+AV   EEA+RRV  LV PFL  NP TNTYLHFL+SQ Y +EVIIFAIFEAYLLGVDS
Sbjct: 240  HKKAVREVEEAQRRVQNLVSPFLSLNPPTNTYLHFLRSQKYDDEVIIFAIFEAYLLGVDS 299

Query: 1069 TSSTTAWALAFLIREPSVQEKLYQELKNFTANNNRTMLKVEDVNKLPYLQAVVKETMRMK 1248
            TS TTAWALAFLIRE +VQEKLYQEL++F +  +R +LKVED+NKL YLQAV+KETMRMK
Sbjct: 300  TSLTTAWALAFLIRESNVQEKLYQELESFASKMDRKILKVEDINKLQYLQAVIKETMRMK 359

Query: 1249 PIAPLAIPHKACKDTSLMGKKVDKGTKVMVNIHALHHTEKVWKEPYKFIPERFLQ----- 1413
            PIAPLAIPHKAC+DTSLMGKK+DKGT+VMVNI+ALHH + V+ +P+KF+PERF++     
Sbjct: 360  PIAPLAIPHKACRDTSLMGKKIDKGTRVMVNIYALHHNKNVFNDPFKFMPERFMKVDSQD 419

Query: 1414 KHDKAMEQSLLPFSAGMRICAGMELGKLQFSFSLANLVNAFKWSCVSDGVLPDMSDLLGF 1593
             + KAMEQSLLPFSAGMRICAGMELGKLQFSF+LANL  AFKWSCV+DGVLPDMSD LGF
Sbjct: 420  ANGKAMEQSLLPFSAGMRICAGMELGKLQFSFALANLAYAFKWSCVADGVLPDMSDQLGF 479

Query: 1594 VLFMKTPLEARI 1629
            VL MKTPLEARI
Sbjct: 480  VLLMKTPLEARI 491


>dbj|BAG75116.1| cytochrome P450 [Eschscholzia californica]
          Length = 495

 Score =  704 bits (1816), Expect = 0.0
 Identities = 353/495 (71%), Positives = 417/495 (84%), Gaps = 7/495 (1%)
 Frame = +1

Query: 175  IKEMIMSNLWILTLISTILAVFAAVLIIFRRRISASTTEWPVGPKTLPIIGNLHILGGTA 354
            IK +IM+N WILT  +T L +  ++ + F R+  +S   WP GPKTLPIIGN+H+LGGTA
Sbjct: 4    IKILIMNNPWILTATATTLLI--SMFLFFTRK--SSKMVWPQGPKTLPIIGNMHLLGGTA 59

Query: 355  LHVVLHKLAEVYGSVMTIWIGSWKPVIIVSDFDRAWEVLVNKSSDYSAREMPEITKIGTA 534
            L VVLH LA+V+GSVMTIWIGSW+PVI+VSD +RAWEVLVNKSSDYSARE+P+I K  TA
Sbjct: 60   LQVVLHNLAKVHGSVMTIWIGSWRPVIVVSDIERAWEVLVNKSSDYSARELPDIIKYNTA 119

Query: 535  NWRTISSSDSGPFWATLRKGLQSVALSPQHLASQTAHQERDIIKLIKNLKDEAAS--GMV 708
            + RTI++ DSGP W+ LRKGLQ+VALSP +LA+Q   QE+D+IK+I  L+ EA +  G+V
Sbjct: 120  DCRTIATCDSGPHWSNLRKGLQNVALSPNNLAAQFQFQEKDVIKMIDILEQEAINKNGIV 179

Query: 709  KPLDHLKKATVRLISRLIYGQDFDDDKYVEDMHDVIEFLIRISGYAQLAEVFYYAKYLPG 888
            KPLDHLKKAT+RLISRL++GQDF+DDKYVED+H  IE LIR+SGYAQLAE FYYAKYLP 
Sbjct: 180  KPLDHLKKATIRLISRLVFGQDFNDDKYVEDLHQAIEELIRMSGYAQLAEAFYYAKYLPS 239

Query: 889  HKRAVTGAEEAKRRVIALVRPFLQSNPATNTYLHFLKSQLYPEEVIIFAIFEAYLLGVDS 1068
            HK+A+  AE  K+ V  LVRPFL  NP TN+YLHFL+SQ Y EE++IFAIFE YLLGVDS
Sbjct: 240  HKKAIRHAELTKQIVTNLVRPFLSLNPPTNSYLHFLQSQKYDEEMVIFAIFETYLLGVDS 299

Query: 1069 TSSTTAWALAFLIREPSVQEKLYQELKNFTANNNRTMLKVEDVNKLPYLQAVVKETMRMK 1248
            TSSTTAWALA+L+REP+VQ++LY EL N+   N+R +LKVE +NKL YLQAV KETMRMK
Sbjct: 300  TSSTTAWALAYLVREPNVQDRLYNELNNYANYNDRKILKVEVINKLQYLQAVTKETMRMK 359

Query: 1249 PIAPLAIPHKACKDTSLMGKKVDKGTKVMVNIHALHHTEKVWKEPYKFIPERFLQKHD-- 1422
            PIAPLAIPHKAC+DTSLMG K+DKGTKVMVN+HALHH E V+ +P+KF+PERFL+ ++  
Sbjct: 360  PIAPLAIPHKACRDTSLMGTKIDKGTKVMVNLHALHHNENVFTDPFKFMPERFLKVNNED 419

Query: 1423 ---KAMEQSLLPFSAGMRICAGMELGKLQFSFSLANLVNAFKWSCVSDGVLPDMSDLLGF 1593
               KAMEQSLLPFSAGMRICAGMELGKLQFSF+LANLV AFKWSCV DGVLPDMSD LGF
Sbjct: 420  VNMKAMEQSLLPFSAGMRICAGMELGKLQFSFALANLVYAFKWSCVDDGVLPDMSDELGF 479

Query: 1594 VLFMKTPLEARIVPR 1638
            VLFMKTPLEARIV R
Sbjct: 480  VLFMKTPLEARIVRR 494


>sp|Q50LH4.1|C7193_ESCCA RecName: Full=(S)-stylopine synthase 2; Short=STS; AltName:
            Full=Cytochrome P450 719A3; Short=EcCYP719A3;
            Short=EcCYPA gi|63108254|dbj|BAD98249.1| stylopine
            synthase [Eschscholzia californica]
          Length = 495

 Score =  701 bits (1808), Expect = 0.0
 Identities = 347/495 (70%), Positives = 420/495 (84%), Gaps = 7/495 (1%)
 Frame = +1

Query: 175  IKEMIMSNLWILTLISTILAVFAAVLIIFRRRISASTTEWPVGPKTLPIIGNLHILGGTA 354
            +K +IM+N W+L   S  L +  ++ + FRR+  +    WP GPKTLPIIGN+H+LGGTA
Sbjct: 4    MKFLIMNNPWVLFATSATLLI--SIFLFFRRK--SPNMAWPEGPKTLPIIGNMHLLGGTA 59

Query: 355  LHVVLHKLAEVYGSVMTIWIGSWKPVIIVSDFDRAWEVLVNKSSDYSAREMPEITKIGTA 534
            L VVL+ LA+V+G VMTIWIGSW+PVI+VSD ++AWEVLVNKSSDYSAR+MP+ITKI TA
Sbjct: 60   LQVVLYNLAKVHGRVMTIWIGSWRPVIVVSDIEQAWEVLVNKSSDYSARDMPDITKIVTA 119

Query: 535  NWRTISSSDSGPFWATLRKGLQSVALSPQHLASQTAHQERDIIKLIKNLKDEAA--SGMV 708
            +WRTIS+SDSGP W+ LRKGLQ++A+SP +LA+Q   QE+DIIK+I+ L+ EA   +G+V
Sbjct: 120  DWRTISTSDSGPHWSNLRKGLQNIAISPNNLAAQFQFQEKDIIKMIQILEQEAKDNNGIV 179

Query: 709  KPLDHLKKATVRLISRLIYGQDFDDDKYVEDMHDVIEFLIRISGYAQLAEVFYYAKYLPG 888
            KPLDHLKKAT+RLISRL++G+DF++DKYVEDMH  IE LIRISGYA+LAE FYYAKYLP 
Sbjct: 180  KPLDHLKKATIRLISRLVFGRDFEEDKYVEDMHHAIEELIRISGYARLAEAFYYAKYLPS 239

Query: 889  HKRAVTGAEEAKRRVIALVRPFLQSNPATNTYLHFLKSQLYPEEVIIFAIFEAYLLGVDS 1068
            H++AV   EE K+ V  L+RPFL  NP TNTYLHFL+SQ Y EEV+IFAIFE YLLGVDS
Sbjct: 240  HRKAVRYVEELKQIVKNLIRPFLSVNPPTNTYLHFLRSQNYDEEVVIFAIFETYLLGVDS 299

Query: 1069 TSSTTAWALAFLIREPSVQEKLYQELKNFTANNNRTMLKVEDVNKLPYLQAVVKETMRMK 1248
            TSSTTAWALA+L+REPSVQ++L+QEL +F   N+R +LKVED+NKL YLQAV+KETMRMK
Sbjct: 300  TSSTTAWALAYLVREPSVQDRLHQELDHFAKQNDRKILKVEDMNKLQYLQAVIKETMRMK 359

Query: 1249 PIAPLAIPHKACKDTSLMGKKVDKGTKVMVNIHALHHTEKVWKEPYKFIPERFLQKHD-- 1422
            PIAPLAIPHKACKDTSLMG K++KGT+VMVN++ALHH + V+ +P+KF+PERFL+  +  
Sbjct: 360  PIAPLAIPHKACKDTSLMGNKINKGTRVMVNLYALHHNKNVFNDPFKFMPERFLKVDNQD 419

Query: 1423 ---KAMEQSLLPFSAGMRICAGMELGKLQFSFSLANLVNAFKWSCVSDGVLPDMSDLLGF 1593
               KAMEQSLLPFSAGMRICAGMELGKLQFSF+LANL+ AFKWSCV DGVLPDMSD LGF
Sbjct: 420  AKGKAMEQSLLPFSAGMRICAGMELGKLQFSFALANLIFAFKWSCVDDGVLPDMSDELGF 479

Query: 1594 VLFMKTPLEARIVPR 1638
            VL MKTPL+ARI PR
Sbjct: 480  VLLMKTPLKARINPR 494


>dbj|BAG75114.1| cytochrome P450 [Eschscholzia californica]
          Length = 495

 Score =  686 bits (1770), Expect = 0.0
 Identities = 345/495 (69%), Positives = 409/495 (82%), Gaps = 7/495 (1%)
 Frame = +1

Query: 175  IKEMIMSNLWILTLISTILAVFAAVLIIFRRRISASTTEWPVGPKTLPIIGNLHILGGT- 351
            +K ++M+N W+LT   T L +  ++ +   R+   S TEWP GPKTLPIIGN+H+LGGT 
Sbjct: 4    MKFLMMNNPWVLTATFTTLLI--SIFLFVTRK--TSNTEWPNGPKTLPIIGNMHLLGGTK 59

Query: 352  ALHVVLHKLAEVYGSVMTIWIGSWKPVIIVSDFDRAWEVLVNKSSDYSAREMPEITKIGT 531
            AL V+LH LA+VYG VMTIWIGSW+PVIIVSD +RAWEVLVNKSSDYSARE+PEI K   
Sbjct: 60   ALQVILHNLAKVYGGVMTIWIGSWRPVIIVSDIERAWEVLVNKSSDYSARELPEIIKYNA 119

Query: 532  ANWRTISSSDSGPFWATLRKGLQSVALSPQHLASQTAHQERDIIKLIKNLKDEAAS--GM 705
            AN+RTI++ DSGP W+ LRKGLQ+VALSP +LA+Q   QE+DI K+I+NL+ EA +  G+
Sbjct: 120  ANFRTIATCDSGPHWSNLRKGLQNVALSPHNLAAQFQFQEKDITKMIQNLEVEAKNNNGI 179

Query: 706  VKPLDHLKKATVRLISRLIYGQDFDDDKYVEDMHDVIEFLIRISGYAQLAEVFYYAKYLP 885
            V+PLDHLKKAT+RLISRLI+GQDFD+D YVE +H  I+ LIR+SGYAQLAE FYYA+YLP
Sbjct: 180  VQPLDHLKKATIRLISRLIFGQDFDEDTYVEKLHHTIDELIRMSGYAQLAEAFYYARYLP 239

Query: 886  GHKRAVTGAEEAKRRVIALVRPFLQSNPATNTYLHFLKSQLYPEEVIIFAIFEAYLLGVD 1065
             HK+AV  A + K+ V  L+RPFL  NP TN+YLHFL+SQ Y EE+IIF+IFE YLLGVD
Sbjct: 240  NHKKAVNHAAKTKQIVTHLMRPFLSLNPPTNSYLHFLQSQNYDEELIIFSIFEVYLLGVD 299

Query: 1066 STSSTTAWALAFLIREPSVQEKLYQELKNFTANNNRTMLKVEDVNKLPYLQAVVKETMRM 1245
            STSSTTAWALA+L+REP+VQE LYQEL NF   N+R +LKVED+NKL YLQAV KETMRM
Sbjct: 300  STSSTTAWALAYLVREPNVQETLYQELDNFAKQNDRKILKVEDINKLQYLQAVTKETMRM 359

Query: 1246 KPIAPLAIPHKACKDTSLMGKKVDKGTKVMVNIHALHHTEKVWKEPYKFIPERFLQKHD- 1422
            KPIAPLAIPHKA +DT+LMGKKV+KGTKVMVN+HALHH E V+ +PYKF+PERFL+ +  
Sbjct: 360  KPIAPLAIPHKASRDTTLMGKKVEKGTKVMVNLHALHHNENVFNDPYKFMPERFLKSYQG 419

Query: 1423 ---KAMEQSLLPFSAGMRICAGMELGKLQFSFSLANLVNAFKWSCVSDGVLPDMSDLLGF 1593
               KAMEQS LPFSAGMRIC GME+GKLQF F+LANL  AFKWSC  +GVLPDMSD LGF
Sbjct: 420  AKAKAMEQSYLPFSAGMRICGGMEVGKLQFGFALANLAYAFKWSCAVNGVLPDMSDELGF 479

Query: 1594 VLFMKTPLEARIVPR 1638
            VLFMKTPLEARIV R
Sbjct: 480  VLFMKTPLEARIVRR 494


>dbj|BAG75115.1| cytochrome P450 [Eschscholzia californica]
          Length = 494

 Score =  660 bits (1702), Expect = 0.0
 Identities = 329/494 (66%), Positives = 407/494 (82%), Gaps = 6/494 (1%)
 Frame = +1

Query: 175  IKEMIMSNLWILTLISTILAVFAAVLIIFRRRISASTTEWPVGPKTLPIIGNLHILGGT- 351
            +K ++M+N W++T  S  L +  ++ + F R+  +S   WP GPKTLPIIGN+H+LGG+ 
Sbjct: 4    MKILMMNNPWVVTATSATLLI--SMFLFFTRK--SSKMVWPKGPKTLPIIGNMHLLGGSK 59

Query: 352  ALHVVLHKLAEVYGSVMTIWIGSWKPVIIVSDFDRAWEVLVNKSSDYSAREMPEITKIGT 531
            AL V+LH L++V+GSVMTIWIG W+PVI+VS+ +R WEVLVNKSSDYS R +P++ K  +
Sbjct: 60   ALQVILHNLSKVHGSVMTIWIGRWRPVIVVSNIERVWEVLVNKSSDYSGRYVPDVIKFVS 119

Query: 532  ANWRTISSSDSGPFWATLRKGLQSVALSPQHLASQTAHQERDIIKLIKNLKDEAAS--GM 705
            A++RTIS+SDSGP W  LRKGLQ+VALSP  LA+Q   QE+DIIK+   L+ EA +  G+
Sbjct: 120  ADFRTISTSDSGPHWTNLRKGLQNVALSPNSLAAQFQFQEKDIIKMTDILEREARNNKGI 179

Query: 706  VKPLDHLKKATVRLISRLIYGQDFDDDKYVEDMHDVIEFLIRISGYAQLAEVFYYAKYLP 885
            VKPLDHLKKATVRLISRL++G +F+DD+YVEDMH+ I+ LI++S YAQLAE FYYAKYLP
Sbjct: 180  VKPLDHLKKATVRLISRLVFGPNFNDDQYVEDMHNTIDELIQMSSYAQLAEAFYYAKYLP 239

Query: 886  GHKRAVTGAEEAKRRVIALVRPFLQSNPATNTYLHFLKSQLYPEEVIIFAIFEAYLLGVD 1065
             H++AV   E+ K+ V  L+RP++  +P  NTYLHFL+SQ Y EEV+IFAIFEAYLLGVD
Sbjct: 240  SHRKAVRHFEQTKQIVKKLIRPYISVSPPPNTYLHFLQSQNYDEEVVIFAIFEAYLLGVD 299

Query: 1066 STSSTTAWALAFLIREPSVQEKLYQELKNFTANNNRTMLKVEDVNKLPYLQAVVKETMRM 1245
            STSSTT WALAFLIREP+VQEKLYQELKNF   N+R ++KVED+NKL YLQAV KETMRM
Sbjct: 300  STSSTTTWALAFLIREPNVQEKLYQELKNFAEQNDREIMKVEDINKLQYLQAVTKETMRM 359

Query: 1246 KPIAPLAIPHKACKDTSLMGKKVDKGTKVMVNIHALHHTEKVWKEPYKFIPERFLQ---K 1416
            KP+APLAIPHKAC++TSLMG  +DKGTKVMVNIH+LHH E V+ +P+ F+PERFL+   +
Sbjct: 360  KPVAPLAIPHKACRETSLMGMPIDKGTKVMVNIHSLHHNENVFSDPFTFMPERFLKVDNQ 419

Query: 1417 HDKAMEQSLLPFSAGMRICAGMELGKLQFSFSLANLVNAFKWSCVSDGVLPDMSDLLGFV 1596
            + KAMEQS LPFSAGMRICAG+ELGKL F F+LANLV AFKWSCV+DGVLPDMS+ LG +
Sbjct: 420  NVKAMEQSYLPFSAGMRICAGIELGKLHFGFALANLVYAFKWSCVADGVLPDMSEELGTI 479

Query: 1597 LFMKTPLEARIVPR 1638
            LFMKTPLEARIV R
Sbjct: 480  LFMKTPLEARIVRR 493


>gb|AAU20771.1| (S)-canadine synthase [Thalictrum flavum subsp. glaucum]
          Length = 492

 Score =  631 bits (1628), Expect = e-178
 Identities = 319/495 (64%), Positives = 391/495 (78%), Gaps = 10/495 (2%)
 Frame = +1

Query: 184  MIMSNLWILTLISTILAVFAAVLIIFRRRISAST---TEWPVGPKTLPIIGNLHILGGTA 354
            M + +LW   L+S  LA+  A+ I+     S+S+    +WP GP  LPIIGNLH LGG  
Sbjct: 1    MELVSLW---LVSATLALVVAITILIPMVTSSSSFSQMKWPTGPNKLPIIGNLHQLGGDV 57

Query: 355  LHVVLHKLAEVYGSVMTIWIGSWKPVIIVSDFDRAWEVLVNKSSDYSAREMPEITKIGTA 534
            LHV L KLA+V+GSVMT+WIG+W+P+I++SD D+AWEVLVNKSSDY AR+MPEITKI +A
Sbjct: 58   LHVALAKLAQVHGSVMTVWIGNWRPIIVISDIDKAWEVLVNKSSDYGARDMPEITKIASA 117

Query: 535  NWRTISSSDSGPFWATLRKGLQSVALSPQHLASQTAHQERDIIKLIKNLKDEAA--SGMV 708
            +W TIS+SD+G FW T+RKGLQS A+ P ++A+Q+  QERD+ +LI+ L+DEAA  + +V
Sbjct: 118  SWHTISTSDAGAFWQTVRKGLQSGAMGPLNIAAQSQFQERDMKRLIQALRDEAAQNNNIV 177

Query: 709  KPLDHLKKATVRLISRLIYGQDFDDDKYVEDMHDVIEFLIRISGYAQLAEVFYYAKYLPG 888
            KPLDH+KK TVRL++RLI+GQ FDDDK+VE MH  I+ +IRISGYA+LAE FYYAKYLP 
Sbjct: 178  KPLDHIKKNTVRLLTRLIFGQTFDDDKFVESMHFEIDDIIRISGYARLAEAFYYAKYLPS 237

Query: 889  HKRAVTGAEEAKRRVIALVRPFLQSNPATNTYLHFLKSQLYPEEVIIFAIFEAYLLGVDS 1068
            HK+A   A   K RV  LV P L SNP TN+YL+FL SQ + EEVIIF IFE YLLGVDS
Sbjct: 238  HKKAEREAYLVKCRVEDLVSPLLSSNPPTNSYLYFLLSQRFSEEVIIFCIFELYLLGVDS 297

Query: 1069 TSSTTAWALAFLIREPSVQEKLYQELKNFTANNNRTMLKVEDVNKLPYLQAVVKETMRMK 1248
            TSSTT WALA+LIRE ++QEKLYQ+ +    + +  ++K+EDV+KL YLQAVVKETMRMK
Sbjct: 298  TSSTTTWALAYLIREQAIQEKLYQDTRMTLGDVD--LVKIEDVSKLKYLQAVVKETMRMK 355

Query: 1249 PIAPLAIPHKACKDTSLMGKKVDKGTKVMVNIHALHHTEKVWKEPYKFIPERFLQKHD-- 1422
            PIAPLAIPHK  KDT+LMG KV KGT++MVN++ALHH + +W  PYKF+PERFLQ  D  
Sbjct: 356  PIAPLAIPHKTAKDTTLMGSKVAKGTRIMVNLYALHHNQNIWTNPYKFMPERFLQGEDGS 415

Query: 1423 ---KAMEQSLLPFSAGMRICAGMELGKLQFSFSLANLVNAFKWSCVSDGVLPDMSDLLGF 1593
               KAMEQS LPFSAGMRICAGM+LGKLQF+F+LANLVNAFKWSCV +G  PDMS+ L F
Sbjct: 416  ASNKAMEQSFLPFSAGMRICAGMDLGKLQFAFALANLVNAFKWSCVEEGKFPDMSEELSF 475

Query: 1594 VLFMKTPLEARIVPR 1638
            VL MKTPLEA+I  R
Sbjct: 476  VLLMKTPLEAKITAR 490


>gb|AGL76711.1| (S)-canadine synthase, partial [Coptis chinensis]
          Length = 491

 Score =  627 bits (1616), Expect = e-177
 Identities = 314/492 (63%), Positives = 387/492 (78%), Gaps = 7/492 (1%)
 Frame = +1

Query: 184  MIMSNLWILTLISTILAVFAAVLIIFRRRISASTTEWPVGPKTLPIIGNLHILGGTALHV 363
            M MS L +   ++ + A    + I+F    S    +WP GP+ LPIIGNLH LG   LHV
Sbjct: 1    MEMSPLLVCATVAIVFATTTIIRILFSSS-SLPQMKWPSGPRKLPIIGNLHQLGDDVLHV 59

Query: 364  VLHKLAEVYGSVMTIWIGSWKPVIIVSDFDRAWEVLVNKSSDYSAREMPEITKIGTANWR 543
             L KLA+V+GS+MTIWIGSW+PVI++SD ++AWEVLVNKS+DY AR+MPEITKI +A+W 
Sbjct: 60   ALAKLAKVHGSMMTIWIGSWRPVIVISDLEKAWEVLVNKSADYGARDMPEITKIASASWH 119

Query: 544  TISSSDSGPFWATLRKGLQSVALSPQHLASQTAHQERDIIKLIKNLKDEAAS--GMVKPL 717
            TIS+SD+GPFW  +RKGLQS A+ P ++A+Q  HQER + +LIK + DEAA+  G+VKPL
Sbjct: 120  TISTSDAGPFWQNVRKGLQSGAMGPFNVAAQNQHQERGMKRLIKAMSDEAANNNGIVKPL 179

Query: 718  DHLKKATVRLISRLIYGQDFDDDKYVEDMHDVIEFLIRISGYAQLAEVFYYAKYLPGHKR 897
            DH+KK TVRL++RLI+GQ+FDD+K++E MH  IE +IRISGYA+LAE FYYAKYLP HK+
Sbjct: 180  DHIKKNTVRLLTRLIFGQNFDDNKFIESMHYEIEDIIRISGYARLAEAFYYAKYLPSHKK 239

Query: 898  AVTGAEEAKRRVIALVRPFLQSNPATNTYLHFLKSQLYPEEVIIFAIFEAYLLGVDSTSS 1077
            A   A   K RV  LVRP L SNP TN+YL+FL SQ + EEVIIF IFE YLLGVDSTSS
Sbjct: 240  AEREAFLVKCRVQELVRPLLSSNPPTNSYLYFLLSQNFEEEVIIFCIFELYLLGVDSTSS 299

Query: 1078 TTAWALAFLIREPSVQEKLYQELKNFTANNNRTMLKVEDVNKLPYLQAVVKETMRMKPIA 1257
            TT WALA+LIRE   QEKLYQ+++    + +  ++K+EDVNKL YLQ VVKETMRMKPIA
Sbjct: 300  TTTWALAYLIREQGAQEKLYQDIRMTLGDVD--LVKIEDVNKLKYLQGVVKETMRMKPIA 357

Query: 1258 PLAIPHKACKDTSLMGKKVDKGTKVMVNIHALHHTEKVWKEPYKFIPERFLQ-----KHD 1422
            PLAIPHK  K+T+LMG KV KGT++MVN++ALHH + +W +PYKF+PERFL+      ++
Sbjct: 358  PLAIPHKTAKETTLMGTKVAKGTRIMVNLYALHHNQNIWPDPYKFMPERFLEGATGTAYN 417

Query: 1423 KAMEQSLLPFSAGMRICAGMELGKLQFSFSLANLVNAFKWSCVSDGVLPDMSDLLGFVLF 1602
            KAMEQS LPFSAGMRICAGM+LGKLQF+F+LANLVNAFKWSCV +G LPDM + L FVL 
Sbjct: 418  KAMEQSFLPFSAGMRICAGMDLGKLQFAFALANLVNAFKWSCVEEGKLPDMGEELSFVLL 477

Query: 1603 MKTPLEARIVPR 1638
            MKTPLEARI  R
Sbjct: 478  MKTPLEARIAGR 489


>sp|Q948Y1.1|C719A_COPJA RecName: Full=(S)-canadine synthase; AltName:
            Full=(S)-tetrahydrocolumbamine oxidase
            (methylenedioxy-bridge-forming); AltName: Full=Cytochrome
            P450 719A1 gi|15822820|dbj|BAB68769.1| methylenedioxy
            bridge-forming enzyme [Coptis japonica]
          Length = 491

 Score =  621 bits (1601), Expect = e-175
 Identities = 315/487 (64%), Positives = 386/487 (79%), Gaps = 10/487 (2%)
 Frame = +1

Query: 208  LTLISTILAVFAAVLIIFRRRISASTT---EWPVGPKTLPIIGNLHILGGTALHVVLHKL 378
            L + +T+  VFA   II R   S+S+    +WP GP+ LPIIGNLH LG   LHV L KL
Sbjct: 6    LLVCATVAIVFATTTII-RILFSSSSLPQMKWPSGPRKLPIIGNLHQLGDDVLHVALAKL 64

Query: 379  AEVYGSVMTIWIGSWKPVIIVSDFDRAWEVLVNKSSDYSAREMPEITKIGTANWRTISSS 558
            A+V+GSVMTIWIGSW+PVI++SD ++AWEVLVNKS+DY AR+MPEITKI +A+W TIS+S
Sbjct: 65   AKVHGSVMTIWIGSWRPVIVISDIEKAWEVLVNKSADYGARDMPEITKIASASWHTISTS 124

Query: 559  DSGPFWATLRKGLQSVALSPQHLASQTAHQERDIIKLIKNLKDEAAS--GMVKPLDHLKK 732
            D+G FW  +RKGLQS A+ P ++A+Q  +QERD+ +LIK + DEAA+  G+VKPLDH+KK
Sbjct: 125  DAGSFWQNVRKGLQSGAMGPLNVAAQNQYQERDMKRLIKAMSDEAANNNGIVKPLDHIKK 184

Query: 733  ATVRLISRLIYGQDFDDDKYVEDMHDVIEFLIRISGYAQLAEVFYYAKYLPGHKRAVTGA 912
             TVRL++RLI+GQ FDD+K++E MH  IE +IRISGYA+LAE FYYAKYLP HK+A   A
Sbjct: 185  NTVRLLTRLIFGQAFDDNKFIESMHYEIEDIIRISGYARLAEAFYYAKYLPSHKKAEREA 244

Query: 913  EEAKRRVIALVRPFLQSNPATNTYLHFLKSQLYPEEVIIFAIFEAYLLGVDSTSSTTAWA 1092
               K RV  LVRP L S P TN+YL+FL SQ + EEVIIF IFE YLLGVDSTSSTT WA
Sbjct: 245  FLVKCRVEELVRPLLSSKPPTNSYLYFLLSQNFEEEVIIFCIFELYLLGVDSTSSTTTWA 304

Query: 1093 LAFLIREPSVQEKLYQELKNFTANNNRTMLKVEDVNKLPYLQAVVKETMRMKPIAPLAIP 1272
            LA+LIRE   QEKLYQ+++    + +  ++K+EDVNKL YLQ VVKETMRMKPIAPLAIP
Sbjct: 305  LAYLIREQGAQEKLYQDIRMTLGDVD--LVKIEDVNKLKYLQGVVKETMRMKPIAPLAIP 362

Query: 1273 HKACKDTSLMGKKVDKGTKVMVNIHALHHTEKVWKEPYKFIPERFLQ-----KHDKAMEQ 1437
            HK  K+T+LMG KV KGT++MVN++ALHH + +W +PYKF+PERFL+      ++KAMEQ
Sbjct: 363  HKTAKETTLMGTKVAKGTRIMVNLYALHHNQNIWPDPYKFMPERFLEGETGTAYNKAMEQ 422

Query: 1438 SLLPFSAGMRICAGMELGKLQFSFSLANLVNAFKWSCVSDGVLPDMSDLLGFVLFMKTPL 1617
            S LPFSAGMRICAGM+LGKLQF+F+LANLVNAFKWSCV +G LPDM + L FVL MKTPL
Sbjct: 423  SFLPFSAGMRICAGMDLGKLQFAFALANLVNAFKWSCVEEGKLPDMGEELSFVLLMKTPL 482

Query: 1618 EARIVPR 1638
            EARI  R
Sbjct: 483  EARIAGR 489


>sp|B5UAQ8.1|C7195_ESCCA RecName: Full=Cheilanthifoline synthase; Short=CHS; AltName:
            Full=Cytochrome P450 719A5 gi|209571368|dbj|BAG75113.1|
            cheilanthifoline synthase [Eschscholzia californica]
          Length = 490

 Score =  597 bits (1540), Expect = e-168
 Identities = 294/489 (60%), Positives = 381/489 (77%), Gaps = 8/489 (1%)
 Frame = +1

Query: 196  NLWILTLISTILAVFAAVLIIFRRRISASTTEWPVGPKTLPIIGNLHILGGTALHVVLHK 375
            +LW++T  +T++ VFA   ++ ++  S ST EWP GPK LPIIGNLH LGG A HVVL  
Sbjct: 4    SLWVVT--ATVVVVFAIAKLL-KKSSSISTMEWPKGPKKLPIIGNLHQLGGEAFHVVLAN 60

Query: 376  LAEVYGSVMTIWIGSWKPVIIVSDFDRAWEVLVNKSSDYSAREMPEITKIGTANWRTISS 555
            LA+++G+VMTIW+G+W+P+I++SD D+AWEVLVNKSSDY+ R+ PEITKI +ANW+ IS 
Sbjct: 61   LAKIHGTVMTIWVGAWRPMIVISDIDKAWEVLVNKSSDYAGRDFPEITKIISANWKNISC 120

Query: 556  SDSGPFWATLRKGLQSVALSPQHLASQTAHQERDIIKLIKNLKDEAA--SGMVKPLDHLK 729
            SDSGPFW  LRKGLQ  AL+P ++ SQ   QERD+  LI +++++A+  +G++KPLD+LK
Sbjct: 121  SDSGPFWQNLRKGLQGGALAPLNVISQYQLQERDMKNLITSMQEKASKNNGILKPLDYLK 180

Query: 730  KATVRLISRLIYGQDFDDDKYVEDMHDVIEFLIRISGYAQLAEVFYYAKYLPGHKRAVTG 909
            + T+RL+SRLI+GQ F+D+ +V+ +H  ++ L+RISGYA LA+ F + + LP HK+++  
Sbjct: 181  EETIRLLSRLIFGQSFNDENFVKGVHLALDDLVRISGYASLADAFKFCENLPSHKKSIRE 240

Query: 910  AEEAKRRVIALVRPFLQSNPATNTYLHFLKSQLYPEEVIIFAIFEAYLLGVDSTSSTTAW 1089
              E   RV+ LV+P+L  NP TNTYL+FL SQ + +EVII A+ E Y LGVDST+ST  W
Sbjct: 241  VHEVNERVVNLVKPYLVKNPPTNTYLYFLNSQKFSDEVIISAVLEVYDLGVDSTASTAVW 300

Query: 1090 ALAFLIREPSVQEKLYQELKNFTANNNRTMLKVEDVNKLPYLQAVVKETMRMKPIAPLAI 1269
            AL FL+REP VQEKLY+E+ + T       +KVEDV+KLPYLQAV+KETMRMKPIAP+AI
Sbjct: 301  ALTFLVREPRVQEKLYKEIIDLTGGER--SVKVEDVSKLPYLQAVMKETMRMKPIAPMAI 358

Query: 1270 PHKACKDTSLMGKKVDKGTKVMVNIHALHHTEKVWKEPYKFIPERFLQKHD------KAM 1431
            PHK  +DTSLMGKKV+KGT +MVN++A+HH  KV+ EPYKFIPERFLQ  +      K M
Sbjct: 359  PHKTSRDTSLMGKKVNKGTSIMVNLYAIHHNPKVFPEPYKFIPERFLQGQESKYGDIKEM 418

Query: 1432 EQSLLPFSAGMRICAGMELGKLQFSFSLANLVNAFKWSCVSDGVLPDMSDLLGFVLFMKT 1611
            EQSLLPFSAGMRICAGMELGKLQ+ FSLA+LV AFKW+C  DG LPD+S+   F+L MK 
Sbjct: 419  EQSLLPFSAGMRICAGMELGKLQYGFSLASLVEAFKWTCAVDGKLPDLSEDHCFILLMKN 478

Query: 1612 PLEARIVPR 1638
            PLEARI PR
Sbjct: 479  PLEARITPR 487


>sp|B1NF20.1|C719E_ARGME RecName: Full=Cheilanthifoline synthase; Short=CHS; AltName:
            Full=Cytochrome P450 719A14 gi|148841094|gb|ABR14722.1|
            cheilanthifoline synthase [Argemone mexicana]
          Length = 494

 Score =  589 bits (1519), Expect = e-165
 Identities = 298/493 (60%), Positives = 377/493 (76%), Gaps = 12/493 (2%)
 Frame = +1

Query: 199  LWILTLISTILAVFAAVLIIFRRRISAS--TTEWPVGPKTLPIIGNLHILGGTALHVVLH 372
            +W++  IST++ V      +  +  S+S  T EWPVGPK LPIIGNLH LGG   HVVL 
Sbjct: 5    IWLI--ISTVIIVLGIAKFLLGKSSSSSLSTMEWPVGPKKLPIIGNLHQLGGDVFHVVLA 62

Query: 373  KLAEVYGSVMTIWIGSWKPVIIVSDFDRAWEVLVNKSSDYSAREMPEITKIGTANWRTIS 552
             LA+VYGSV TIW+GSW+P+IIVSD D+AWEVLVNKSSDYSAR+MP+ITKI +ANW+ IS
Sbjct: 63   NLAKVYGSVFTIWVGSWRPMIIVSDIDKAWEVLVNKSSDYSARDMPDITKIISANWKNIS 122

Query: 553  SSDSGPFWATLRKGLQSVALSPQHLASQTAHQERDIIKLIKNLKDEAA--SGMVKPLDHL 726
             SDSGPFW  LRKGLQ VAL+P ++ASQ   QERD+  LI ++  +A+  +G++KPLD+L
Sbjct: 123  CSDSGPFWHNLRKGLQGVALTPLNVASQYHLQERDMKNLINSMYKDASRKNGILKPLDYL 182

Query: 727  KKATVRLISRLIYGQDFDDDKYVEDMHDVIEFLIRISGYAQLAEVFYYAKYLPGHKRAVT 906
            K+ TVRL+SRLI+GQDF D+K V  MH  ++ L+RISGYA LA+ F + + LP HK+++ 
Sbjct: 183  KEETVRLLSRLIFGQDFQDEKLVVGMHHALDDLVRISGYASLADAFKFCENLPSHKKSIR 242

Query: 907  GAEEAKRRVIALVRPFLQSNPATNTYLHFLKSQLYPEEVIIFAIFEAYLLGVDSTSSTTA 1086
               E K+RV  L+RP + SNP TNTYL+FLK+Q + E++II AI E Y LGVDST+STT 
Sbjct: 243  EVHEVKKRVENLIRPHIVSNPPTNTYLYFLKTQDFNEDIIISAILEVYDLGVDSTASTTV 302

Query: 1087 WALAFLIREPSVQEKLYQELKNFTANNNRTMLKVEDVNKLPYLQAVVKETMRMKPIAPLA 1266
            WAL FL+RE  +QEKLY+E+ N T    +  +KVEDVNK+PYLQAV+KETMRMKPIAP+A
Sbjct: 303  WALTFLVREQEIQEKLYREIVNVT--GGKRSVKVEDVNKMPYLQAVMKETMRMKPIAPMA 360

Query: 1267 IPHKACKDTSLMGKKVDKGTKVMVNIHALHHTEKVWKEPYKFIPERFLQK--------HD 1422
            IPHK  KDTSLMGKK++KG+ +MVN++A+HH  KV+ EPYKF+PERFL+         + 
Sbjct: 361  IPHKTSKDTSLMGKKINKGSVIMVNLYAIHHNPKVFPEPYKFMPERFLKDVNSDESLGNI 420

Query: 1423 KAMEQSLLPFSAGMRICAGMELGKLQFSFSLANLVNAFKWSCVSDGVLPDMSDLLGFVLF 1602
            K ME SLL FSAGMRICAGMELGKLQ +F LA+LV+ FKWSC  DG LPD+S+   F+L 
Sbjct: 421  KTMESSLLAFSAGMRICAGMELGKLQLAFGLASLVHEFKWSCSVDGKLPDLSEDHCFILL 480

Query: 1603 MKTPLEARIVPRL 1641
            MK PLEA+I  R+
Sbjct: 481  MKNPLEAKITCRI 493


>gb|ADB89213.1| cheilanthifoline synthase [Papaver somniferum]
          Length = 492

 Score =  588 bits (1516), Expect = e-165
 Identities = 295/490 (60%), Positives = 370/490 (75%), Gaps = 10/490 (2%)
 Frame = +1

Query: 202  WILTLISTILAVFAAVLIIFRRRISASTTEWPVGPKTLPIIGNLHILGGTALHVVLHKLA 381
            W++T    ++  FA   ++F ++ S ST EWP GPKTLPIIGNLH LGG A HV L  LA
Sbjct: 6    WLITC--GVVVAFALAKLLFGKKSSMSTMEWPSGPKTLPIIGNLHQLGGEAFHVCLANLA 63

Query: 382  EVYGSVMTIWIGSWKPVIIVSDFDRAWEVLVNKSSDYSAREMPEITKIGTANWRTISSSD 561
            +VYG V TIW+GSW+P I++SD D+AWEVLVNKSSDYSAR+MP+ITKI +ANW+ IS  D
Sbjct: 64   KVYGGVFTIWVGSWRPFIVISDVDKAWEVLVNKSSDYSARDMPDITKIISANWKNISHGD 123

Query: 562  SGPFWATLRKGLQSVALSPQHLASQTAHQERDIIKLIKNLKDEAA--SGMVKPLDHLKKA 735
            SGPFW  LRKGLQ VAL+P ++ASQ   QERD+  LIK++K +A+  +G++KPLD++K+ 
Sbjct: 124  SGPFWHNLRKGLQGVALTPFNVASQYHLQERDMQNLIKSMKKKASQKNGILKPLDYVKEE 183

Query: 736  TVRLISRLIYGQDFDDDKYVEDMHDVIEFLIRISGYAQLAEVFYYAKYLPGHKRAVTGAE 915
            TVRL+SRLI+GQDF D+ +V  MH  ++ L+ ISGYA LA+ F + + LP HK+ V    
Sbjct: 184  TVRLLSRLIFGQDFVDEDFVVGMHQALDELVSISGYASLADAFKFCENLPSHKKTVRAVH 243

Query: 916  EAKRRVIALVRPFLQSNPATNTYLHFLKSQLYPEEVIIFAIFEAYLLGVDSTSSTTAWAL 1095
              K R   L+RP + SNP TNTYLHFL SQ + E+VII AI E Y LGVDST+STT WAL
Sbjct: 244  AIKIRFDNLIRPHIVSNPPTNTYLHFLLSQDFSEDVIISAILEVYDLGVDSTASTTVWAL 303

Query: 1096 AFLIREPSVQEKLYQELKNFTANNNRTMLKVEDVNKLPYLQAVVKETMRMKPIAPLAIPH 1275
             FL+RE  +QEKLY+E+ N T    +  +KVED+NKLPYLQAV+KETMRMKPIAP+AIPH
Sbjct: 304  TFLVREQKIQEKLYREINNVT--GGKKPVKVEDLNKLPYLQAVMKETMRMKPIAPMAIPH 361

Query: 1276 KACKDTSLMGKKVDKGTKVMVNIHALHHTEKVWKEPYKFIPERFLQKHD--------KAM 1431
            KA KDTSLMGKK++KG  VMVN++A+HH   V+ EPYKF+PERFL+  +        K M
Sbjct: 362  KASKDTSLMGKKINKGAVVMVNLYAIHHNPAVFPEPYKFMPERFLKDANSDGSLGDIKKM 421

Query: 1432 EQSLLPFSAGMRICAGMELGKLQFSFSLANLVNAFKWSCVSDGVLPDMSDLLGFVLFMKT 1611
            E SLL FSAGMRICAGMELGKLQ +F LA+LVN FKW C ++G LPD+S+   F+L MK 
Sbjct: 422  ESSLLAFSAGMRICAGMELGKLQLAFGLASLVNEFKWDCFAEGKLPDLSEEHCFILLMKN 481

Query: 1612 PLEARIVPRL 1641
            PLEA+I PR+
Sbjct: 482  PLEAKITPRI 491


>dbj|BAF98470.1| cytochrome P450 [Coptis japonica var. dissecta]
          Length = 491

 Score =  561 bits (1447), Expect = e-157
 Identities = 284/486 (58%), Positives = 364/486 (74%), Gaps = 9/486 (1%)
 Frame = +1

Query: 208  LTLISTILAVFAAVLIIFRRRISASTTE--WPVGPKTLPIIGNLHILGGTALHVVLHKLA 381
            L LI + +A+   +  I R   S+S+++  WP GPK LPIIGNLH+LGG  LHV L KLA
Sbjct: 6    LWLIGSTVAIVLVITTIVRMSSSSSSSKKKWPSGPKRLPIIGNLHLLGGDLLHVTLAKLA 65

Query: 382  EVYGSVMTIWIGSWKPVIIVSDFDRAWEVLVNKSSDYSAREMPEITKIGTANWRTISSSD 561
            +V+GSVMTIWIG W+P+I++SD + AWEVLV+KS++Y  R+ P+I K  T     IS SD
Sbjct: 66   KVHGSVMTIWIGRWRPIIVISDINSAWEVLVSKSAEYGQRDTPDIFKTLTVGQNNISMSD 125

Query: 562  SGPFWATLRKGLQSVALSPQHLASQTAHQERDIIKLIKNLKDEAAS--GMVKPLDHLKKA 735
             GPFW  +RKGLQ+ ALSP ++A+QT  +E D+ +LI  +  EA +  G++KPLDH+KK 
Sbjct: 126  IGPFWHNVRKGLQNGALSPLNVAAQTQFREEDVKRLIHEMSREALNKNGIIKPLDHMKKN 185

Query: 736  TVRLISRLIYGQDFDDDKYVEDMHDVIEFLIRISGYAQLAEVFYYAKYLPGHKRAVTGAE 915
            T RL+ RLI+G  FD+DK+VE +   IE ++R+SGYA+L E FYYAKYLP  K+    A 
Sbjct: 186  TARLLGRLIFGPTFDNDKFVESVLYEIEDVLRLSGYARLTEAFYYAKYLPSQKKVAREAY 245

Query: 916  EAKRRVIALVRPFLQSNPATNTYLHFLKSQLYPEEVIIFAIFEAYLLGVDSTSSTTAWAL 1095
             AK R+  L+RP L SNP TN+YL+FL+SQ Y +E+IIF  FE +LLGVDSTSST  WAL
Sbjct: 246  LAKYRIEELMRPLLSSNPPTNSYLYFLQSQNYSKEIIIFCTFELFLLGVDSTSSTATWAL 305

Query: 1096 AFLIREPSVQEKLYQELKNFTANNNRTMLKVEDVNKLPYLQAVVKETMRMKPIAPLAIPH 1275
            A+LI E +VQEKL ++++    + +  ++K+ED++KL YLQAVVKETMRMKPIAPLAIPH
Sbjct: 306  AYLIHEQAVQEKLNEDIRMTIGDVD--LVKIEDLSKLKYLQAVVKETMRMKPIAPLAIPH 363

Query: 1276 KACKDTSLMGKKVDKGTKVMVNIHALHHTEKVWKEPYKFIPERFLQ-----KHDKAMEQS 1440
            K   DT+LMG KV +GT++MVN++ALHH E +W EPYKF+PERFLQ      ++KAMEQS
Sbjct: 364  KTANDTTLMGTKVARGTQIMVNLYALHHNEDIWPEPYKFMPERFLQGENVSANNKAMEQS 423

Query: 1441 LLPFSAGMRICAGMELGKLQFSFSLANLVNAFKWSCVSDGVLPDMSDLLGFVLFMKTPLE 1620
             LPF AGMRICAGM+LGKLQ +F+LANLVNAFKWSCV +G LPDMS+ L  V  MKTPLE
Sbjct: 424  FLPFGAGMRICAGMDLGKLQIAFALANLVNAFKWSCVDEGKLPDMSEQLFAVTLMKTPLE 483

Query: 1621 ARIVPR 1638
             RI  R
Sbjct: 484  GRISTR 489


>dbj|BAF98471.1| cytochrome P450 [Coptis japonica var. dissecta]
          Length = 508

 Score =  541 bits (1394), Expect = e-151
 Identities = 285/502 (56%), Positives = 352/502 (70%), Gaps = 11/502 (2%)
 Frame = +1

Query: 166  IPIIKEMIMSNLWILTLISTILAVFAAVLIIFRRRISASTTEWPVGPKTLPIIGNLHILG 345
            + ++ EM  S L     ++ +L +   V I      S S   WP GPK LPIIGNLH L 
Sbjct: 7    VAMVAEMEGSLLLAGATLAILLTISTIVRITSSPSSSFSQMTWPSGPKKLPIIGNLHQLR 66

Query: 346  GTALHVVLHKLAEVYGSVMTIWIGSWKPVIIVSDFDRAWEVLVNKSSDYSAREMP---EI 516
            G  LHV L KLA+V+G VMTIW+GSW P+I++SD + AWEVLVNKS+DY ARE+    E+
Sbjct: 67   GELLHVTLAKLAKVHGGVMTIWMGSWVPIIVISDINSAWEVLVNKSADYGAREVTYLHEL 126

Query: 517  TKIGTANWRTISSSDSGPFWATLRKGLQSVALSPQHLASQTAHQERDIIKLIKNLKDEAA 696
             +    +   ISSSD GP W  +RKGLQS ALSP  +ASQT H+ERD+ +++  +  E  
Sbjct: 127  LRDSAMHPHNISSSDVGPLWHNIRKGLQSGALSPLSVASQTQHRERDMKRVVHEMSREIV 186

Query: 697  S--GMVKPLDHLKKATVRLISRLIYGQDFDDDKYVEDMHDVIEFLIRISGYAQLAEVFYY 870
            +  G +KPL H+K +T RL+ RLI+G  F+D K++E M   IE  IR S Y  L   FYY
Sbjct: 187  NNNGTIKPLVHIKNSTARLLGRLIFGPSFNDSKFIESMLYEIEDFIRTSSYTSLTNSFYY 246

Query: 871  AKYLPGHKRAVTGAEEAKRRVIALVRPFLQSNPATNTYLHFLKSQLYPEEVIIFAIFEAY 1050
            AKYLP  ++A   A+  K R+  LVRP L S P TN YL+FL SQ   EEV IF IFE +
Sbjct: 247  AKYLPSQRKATREAKLGKYRIEELVRPLLSSKPPTNAYLYFLLSQNLSEEVTIFCIFELF 306

Query: 1051 LLGVDSTSSTTAWALAFLIREPSVQEKLYQELKNFTANNNRTMLKVEDVNKLPYLQAVVK 1230
            LLGVDS SSTT WALA++IRE   QEKLYQ+++    + +  ++K+EDVNKL YLQ+VVK
Sbjct: 307  LLGVDSASSTTTWALAYMIREQEAQEKLYQDIRMTIGDVD--LVKIEDVNKLKYLQSVVK 364

Query: 1231 ETMRMKPIAPLAIPHKACKDTSLMGKKVDKGTKVMVNIHALHHTEKVWKEPYKFIPERFL 1410
            ETMRMKPIAPLA+PH A KDT+LMG K+ KGT+VMVN++ALHH E VW EP KF+PER+L
Sbjct: 365  ETMRMKPIAPLALPHNAGKDTTLMGTKIVKGTRVMVNLYALHHYEDVWLEPSKFMPERYL 424

Query: 1411 QKHD-----KAMEQSLLPFSAGMRICAGMELGKLQFSFSLANLVNAFKWSCVSDGVLPDM 1575
            Q  D     KAMEQSLLPF AGMRICAGM+LGKLQ +F LANLVNAFKWSCV DG LPDM
Sbjct: 425  QGEDGSVTHKAMEQSLLPFGAGMRICAGMDLGKLQVAFVLANLVNAFKWSCVEDGKLPDM 484

Query: 1576 S-DLLGFVLFMKTPLEARIVPR 1638
            + +L G ++ MKTPLE RI PR
Sbjct: 485  TEELFGLIILMKTPLEGRISPR 506


>gb|AGC29954.1| CYP719A24 [Podophyllum peltatum]
          Length = 489

 Score =  538 bits (1385), Expect = e-150
 Identities = 275/483 (56%), Positives = 358/483 (74%), Gaps = 5/483 (1%)
 Frame = +1

Query: 205  ILTLISTILAVFAAVLIIFRRRISASTTEWPVGPKTLPIIGNLHILGGTALHVVLHKLAE 384
            +L L ST++   A  +I   +  S+S  +WP GPKTLPIIGNLH LGG  LH+VL KLA 
Sbjct: 7    VLGLSSTLIIALAITVIFLLKAKSSSAIKWPPGPKTLPIIGNLHQLGGDELHIVLAKLAR 66

Query: 385  VYGSVMTIWIGSWKPVIIVSDFDRAWEVLVNKSSDYSAREMPEITKIGTANWRTISSSDS 564
            V+G++MTIW+   KPVI+VSD +  WEVLV+KSSDY+AR+  EI+KI +A+  +I++SDS
Sbjct: 67   VHGAIMTIWMAK-KPVIVVSDVNSVWEVLVSKSSDYAARDAAEISKIVSASSHSINTSDS 125

Query: 565  GPFWATLRKGLQSVALSPQHLASQTAHQERDIIKLIKNLKDEAAS--GMVKPLDHLKKAT 738
            GP+W TLR+GL    L P ++++Q   Q+RD+ ++I+ ++ +AA+  G++KPLDHLK+++
Sbjct: 126  GPYWQTLRRGLTHGPLGPLNISAQIPIQQRDMQRVIREMQQDAAANGGVIKPLDHLKRSS 185

Query: 739  VRLISRLIYGQDFDDDKYVEDMHDVIEFLIRISGYAQLAEVFYYAKYLPGHKRAVTGAEE 918
             RL+SRLI+G  FD+D Y + MH+V++ L R  G A L + F +AKYLP +KR V     
Sbjct: 186  TRLVSRLIFGDTFDNDPYNDSMHEVVQDLNRFGGIALLEQAFSFAKYLPSYKRGVKEFHI 245

Query: 919  AKRRVIALVRPFL-QSNPATNTYLHFLKSQLYPEEVIIFAIFEAYLLGVDSTSSTTAWAL 1095
             KR++  LVRP +  SNP +N+YL FL+SQ Y EE+II  IFE YLL  DS++ST  WAL
Sbjct: 246  HKRKIDDLVRPVVASSNPPSNSYLGFLQSQNYSEEIIIACIFELYLLXXDSSASTATWAL 305

Query: 1096 AFLIREPSVQEKLYQELKNFTANNNRTMLKVEDVNKLPYLQAVVKETMRMKPIAPLAIPH 1275
            AF IR+  VQEKLYQ++K     +   ++K ED++K+ YLQAVVKETMRMKPIAPLAIPH
Sbjct: 306  AFXIRDQQVQEKLYQDIKR-VIGDEVGLVKAEDLSKMHYLQAVVKETMRMKPIAPLAIPH 364

Query: 1276 KACKDTSLMGKKVDKGTKVMVNIHALHHTEKVWKEPYKFIPERFLQKHD--KAMEQSLLP 1449
            K   DTSLMG KV KGT VMVN++ALHH E VW +PY F+PERFLQ+ D     EQ+ LP
Sbjct: 365  KTAIDTSLMGTKVPKGTCVMVNLYALHHDESVWAKPYTFMPERFLQREDGKSVTEQAFLP 424

Query: 1450 FSAGMRICAGMELGKLQFSFSLANLVNAFKWSCVSDGVLPDMSDLLGFVLFMKTPLEARI 1629
            F AGMRIC GME+GKLQFS +LANLVNAFKW+  ++G LPDMSD L F+  MKTPLEARI
Sbjct: 425  FGAGMRICGGMEVGKLQFSLALANLVNAFKWTSAAEGKLPDMSDELQFITVMKTPLEARI 484

Query: 1630 VPR 1638
            VPR
Sbjct: 485  VPR 487