BLASTX 2.2.25 [Feb-01-2011]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= Papaver25_contig00007700
         (1261 letters)

Database: ./nr 
           38,876,450 sequences; 13,856,398,315 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gb|ADB89213.1| cheilanthifoline synthase [Papaver somniferum]         479   e-132
sp|B1NF20.1|C719E_ARGME RecName: Full=Cheilanthifoline synthase;...   476   e-131
sp|B5UAQ8.1|C7195_ESCCA RecName: Full=Cheilanthifoline synthase;...   449   e-124
sp|B1NF18.1|C719B_PAPSO RecName: Full=Salutaridine synthase; Alt...   417   e-114
sp|Q50LH3.1|C7192_ESCCA RecName: Full=(S)-stylopine synthase 1; ...   389   e-105
sp|B1NF19.1|C719D_ARGME RecName: Full=(S)-stylopine synthase; Sh...   387   e-105
gb|AGL76711.1| (S)-canadine synthase, partial [Coptis chinensis]      385   e-104
gb|AHF65153.1| stylopine synthase, partial [synthetic construct]      384   e-104
gb|ADB89214.1| stylopine synthase [Papaver somniferum]                384   e-104
gb|ACO90219.1| stylopine synthase [Eschscholzia californica]          384   e-104
sp|Q948Y1.1|C719A_COPJA RecName: Full=(S)-canadine synthase; Alt...   384   e-104
gb|AAU20771.1| (S)-canadine synthase [Thalictrum flavum subsp. g...   381   e-103
gb|AFI57927.1| cytochrome P450, partial [Papaver somniferum]          381   e-103
sp|Q50LH4.1|C7193_ESCCA RecName: Full=(S)-stylopine synthase 2; ...   379   e-102
gb|AFB74615.1| cytochrome P450 [Papaver somniferum]                   376   e-101
dbj|BAG75116.1| cytochrome P450 [Eschscholzia californica]            376   e-101
dbj|BAF98470.1| cytochrome P450 [Coptis japonica var. dissecta]       376   e-101
dbj|BAF98471.1| cytochrome P450 [Coptis japonica var. dissecta]       366   1e-98
dbj|BAG75114.1| cytochrome P450 [Eschscholzia californica]            357   8e-96
dbj|BAG75115.1| cytochrome P450 [Eschscholzia californica]            355   3e-95

>gb|ADB89213.1| cheilanthifoline synthase [Papaver somniferum]
          Length = 492

 Score =  479 bits (1233), Expect = e-132
 Identities = 243/419 (57%), Positives = 303/419 (72%)
 Frame = +3

Query: 3    IGNLHQLRGDDFHVRMANFAKVHGGIFTLWIGSWHPVIIINDIASAWEVLVTXXXXXXXX 182
            IGNLHQL G+ FHV +AN AKV+GG+FT+W+GSW P I+I+D+  AWEVLV         
Sbjct: 44   IGNLHQLGGEAFHVCLANLAKVYGGVFTIWVGSWRPFIVISDVDKAWEVLVNKSSDYSAR 103

Query: 183  XXXXXXXXXVNSAGNEKYTNIAESDVGPFWTNLRKGLQSVALGPLNVTSQTHLQERSMHR 362
                     +    +  + NI+  D GPFW NLRKGLQ VAL P NV SQ HLQER M  
Sbjct: 104  DMPD-----ITKIISANWKNISHGDSGPFWHNLRKGLQGVALTPFNVASQYHLQERDMQN 158

Query: 363  LIKSMQQKALQQNGILKPLDYLKEESIRLLSVLIFGQDFSDENFVVRMNRILYDLVRIDQ 542
            LIKSM++KA Q+NGILKPLDY+KEE++RLLS LIFGQDF DE+FVV M++ L +LV I  
Sbjct: 159  LIKSMKKKASQKNGILKPLDYVKEETVRLLSRLIFGQDFVDEDFVVGMHQALDELVSISG 218

Query: 543  ITSLSDAFHIAKYLPSSKKVIRELDDVMEQAASLIIPYISTSKTPPANTYLNFLKSQDYX 722
              SL+DAF   + LPS KK +R +  +  +  +LI P+I ++  PP NTYL+FL SQD+ 
Sbjct: 219  YASLADAFKFCENLPSHKKTVRAVHAIKIRFDNLIRPHIVSN--PPTNTYLHFLLSQDFS 276

Query: 723  XXXXXXXXXXXYTLGVDSTSEAIVWALTFLVRDPKIQEKLYHEIKNVTGGNRPVQVNDLK 902
                       Y LGVDST+   VWALTFLVR+ KIQEKLY EI NVTGG +PV+V DL 
Sbjct: 277  EDVIISAILEVYDLGVDSTASTTVWALTFLVREQKIQEKLYREINNVTGGKKPVKVEDLN 336

Query: 903  KMSYLQAVMRETLRMKPIGPVIFTHEAAKDTSLMGKKVGKGTRIMVNLRAIHYNSKVFPE 1082
            K+ YLQAVM+ET+RMKPI P+   H+A+KDTSLMGKK+ KG  +MVNL AIH+N  VFPE
Sbjct: 337  KLPYLQAVMKETMRMKPIAPMAIPHKASKDTSLMGKKINKGAVVMVNLYAIHHNPAVFPE 396

Query: 1083 PYKFIPERYIKEVNRDASLGDREKMESSLIAFGAGMRVCAGIDLAKIIVPFGIASLVNE 1259
            PYKF+PER++K+ N D SLGD +KMESSL+AF AGMR+CAG++L K+ + FG+ASLVNE
Sbjct: 397  PYKFMPERFLKDANSDGSLGDIKKMESSLLAFSAGMRICAGMELGKLQLAFGLASLVNE 455


>sp|B1NF20.1|C719E_ARGME RecName: Full=Cheilanthifoline synthase; Short=CHS; AltName:
            Full=Cytochrome P450 719A14 gi|148841094|gb|ABR14722.1|
            cheilanthifoline synthase [Argemone mexicana]
          Length = 494

 Score =  476 bits (1224), Expect = e-131
 Identities = 246/419 (58%), Positives = 303/419 (72%)
 Frame = +3

Query: 3    IGNLHQLRGDDFHVRMANFAKVHGGIFTLWIGSWHPVIIINDIASAWEVLVTXXXXXXXX 182
            IGNLHQL GD FHV +AN AKV+G +FT+W+GSW P+II++DI  AWEVLV         
Sbjct: 46   IGNLHQLGGDVFHVVLANLAKVYGSVFTIWVGSWRPMIIVSDIDKAWEVLVNKSSDYSAR 105

Query: 183  XXXXXXXXXVNSAGNEKYTNIAESDVGPFWTNLRKGLQSVALGPLNVTSQTHLQERSMHR 362
                     +    +  + NI+ SD GPFW NLRKGLQ VAL PLNV SQ HLQER M  
Sbjct: 106  DMPD-----ITKIISANWKNISCSDSGPFWHNLRKGLQGVALTPLNVASQYHLQERDMKN 160

Query: 363  LIKSMQQKALQQNGILKPLDYLKEESIRLLSVLIFGQDFSDENFVVRMNRILYDLVRIDQ 542
            LI SM + A ++NGILKPLDYLKEE++RLLS LIFGQDF DE  VV M+  L DLVRI  
Sbjct: 161  LINSMYKDASRKNGILKPLDYLKEETVRLLSRLIFGQDFQDEKLVVGMHHALDDLVRISG 220

Query: 543  ITSLSDAFHIAKYLPSSKKVIRELDDVMEQAASLIIPYISTSKTPPANTYLNFLKSQDYX 722
              SL+DAF   + LPS KK IRE+ +V ++  +LI P+I ++  PP NTYL FLK+QD+ 
Sbjct: 221  YASLADAFKFCENLPSHKKSIREVHEVKKRVENLIRPHIVSN--PPTNTYLYFLKTQDFN 278

Query: 723  XXXXXXXXXXXYTLGVDSTSEAIVWALTFLVRDPKIQEKLYHEIKNVTGGNRPVQVNDLK 902
                       Y LGVDST+   VWALTFLVR+ +IQEKLY EI NVTGG R V+V D+ 
Sbjct: 279  EDIIISAILEVYDLGVDSTASTTVWALTFLVREQEIQEKLYREIVNVTGGKRSVKVEDVN 338

Query: 903  KMSYLQAVMRETLRMKPIGPVIFTHEAAKDTSLMGKKVGKGTRIMVNLRAIHYNSKVFPE 1082
            KM YLQAVM+ET+RMKPI P+   H+ +KDTSLMGKK+ KG+ IMVNL AIH+N KVFPE
Sbjct: 339  KMPYLQAVMKETMRMKPIAPMAIPHKTSKDTSLMGKKINKGSVIMVNLYAIHHNPKVFPE 398

Query: 1083 PYKFIPERYIKEVNRDASLGDREKMESSLIAFGAGMRVCAGIDLAKIIVPFGIASLVNE 1259
            PYKF+PER++K+VN D SLG+ + MESSL+AF AGMR+CAG++L K+ + FG+ASLV+E
Sbjct: 399  PYKFMPERFLKDVNSDESLGNIKTMESSLLAFSAGMRICAGMELGKLQLAFGLASLVHE 457


>sp|B5UAQ8.1|C7195_ESCCA RecName: Full=Cheilanthifoline synthase; Short=CHS; AltName:
            Full=Cytochrome P450 719A5 gi|209571368|dbj|BAG75113.1|
            cheilanthifoline synthase [Eschscholzia californica]
          Length = 490

 Score =  449 bits (1156), Expect = e-124
 Identities = 233/417 (55%), Positives = 292/417 (70%)
 Frame = +3

Query: 3    IGNLHQLRGDDFHVRMANFAKVHGGIFTLWIGSWHPVIIINDIASAWEVLVTXXXXXXXX 182
            IGNLHQL G+ FHV +AN AK+HG + T+W+G+W P+I+I+DI  AWEVLV         
Sbjct: 43   IGNLHQLGGEAFHVVLANLAKIHGTVMTIWVGAWRPMIVISDIDKAWEVLVNKSSDYAGR 102

Query: 183  XXXXXXXXXVNSAGNEKYTNIAESDVGPFWTNLRKGLQSVALGPLNVTSQTHLQERSMHR 362
                     +    +  + NI+ SD GPFW NLRKGLQ  AL PLNV SQ  LQER M  
Sbjct: 103  DFPE-----ITKIISANWKNISCSDSGPFWQNLRKGLQGGALAPLNVISQYQLQERDMKN 157

Query: 363  LIKSMQQKALQQNGILKPLDYLKEESIRLLSVLIFGQDFSDENFVVRMNRILYDLVRIDQ 542
            LI SMQ+KA + NGILKPLDYLKEE+IRLLS LIFGQ F+DENFV  ++  L DLVRI  
Sbjct: 158  LITSMQEKASKNNGILKPLDYLKEETIRLLSRLIFGQSFNDENFVKGVHLALDDLVRISG 217

Query: 543  ITSLSDAFHIAKYLPSSKKVIRELDDVMEQAASLIIPYISTSKTPPANTYLNFLKSQDYX 722
              SL+DAF   + LPS KK IRE+ +V E+  +L+ PY+   K PP NTYL FL SQ + 
Sbjct: 218  YASLADAFKFCENLPSHKKSIREVHEVNERVVNLVKPYLV--KNPPTNTYLYFLNSQKFS 275

Query: 723  XXXXXXXXXXXYTLGVDSTSEAIVWALTFLVRDPKIQEKLYHEIKNVTGGNRPVQVNDLK 902
                       Y LGVDST+   VWALTFLVR+P++QEKLY EI ++TGG R V+V D+ 
Sbjct: 276  DEVIISAVLEVYDLGVDSTASTAVWALTFLVREPRVQEKLYKEIIDLTGGERSVKVEDVS 335

Query: 903  KMSYLQAVMRETLRMKPIGPVIFTHEAAKDTSLMGKKVGKGTRIMVNLRAIHYNSKVFPE 1082
            K+ YLQAVM+ET+RMKPI P+   H+ ++DTSLMGKKV KGT IMVNL AIH+N KVFPE
Sbjct: 336  KLPYLQAVMKETMRMKPIAPMAIPHKTSRDTSLMGKKVNKGTSIMVNLYAIHHNPKVFPE 395

Query: 1083 PYKFIPERYIKEVNRDASLGDREKMESSLIAFGAGMRVCAGIDLAKIIVPFGIASLV 1253
            PYKFIPER+++   +++  GD ++ME SL+ F AGMR+CAG++L K+   F +ASLV
Sbjct: 396  PYKFIPERFLQ--GQESKYGDIKEMEQSLLPFSAGMRICAGMELGKLQYGFSLASLV 450


>sp|B1NF18.1|C719B_PAPSO RecName: Full=Salutaridine synthase; AltName: Full=Cytochrome P450
            719B1 gi|148841090|gb|ABR14720.1| salutaridine synthase
            [Papaver somniferum]
          Length = 505

 Score =  417 bits (1073), Expect = e-114
 Identities = 223/420 (53%), Positives = 288/420 (68%), Gaps = 1/420 (0%)
 Frame = +3

Query: 3    IGNLHQLRGD-DFHVRMANFAKVHGGIFTLWIGSWHPVIIINDIASAWEVLVTXXXXXXX 179
            IGNLHQL G     V +AN AKV+GG FT+WIGSW P+I+I+DI +A EVLV        
Sbjct: 53   IGNLHQLGGGVPLQVALANLAKVYGGAFTIWIGSWVPMIVISDIDNAREVLVNKSADYSA 112

Query: 180  XXXXXXXXXXVNSAGNEKYTNIAESDVGPFWTNLRKGLQSVALGPLNVTSQTHLQERSMH 359
                        +       NIA+ D GPFW NL+KGLQS  + P NV S + LQE+ M 
Sbjct: 113  RDVPDILKIITANG-----KNIADCDSGPFWHNLKKGLQS-CINPSNVMSLSRLQEKDMQ 166

Query: 360  RLIKSMQQKALQQNGILKPLDYLKEESIRLLSVLIFGQDFSDENFVVRMNRILYDLVRID 539
             LIKSMQ++A Q NGI+KPLD+ KE S+RLLS +IFG DFS+E+ V+ +   L ++VRI 
Sbjct: 167  NLIKSMQERASQHNGIIKPLDHAKEASMRLLSRVIFGHDFSNEDLVIGVKDALDEMVRIS 226

Query: 540  QITSLSDAFHIAKYLPSSKKVIRELDDVMEQAASLIIPYISTSKTPPANTYLNFLKSQDY 719
             + SL+DAF IAKYLPS +K IR++    ++  +LI P+I  +   PAN++L FL SQDY
Sbjct: 227  GLASLADAFKIAKYLPSQRKNIRDMYATRDRVYNLIQPHIVPNL--PANSFLYFLTSQDY 284

Query: 720  XXXXXXXXXXXXYTLGVDSTSEAIVWALTFLVRDPKIQEKLYHEIKNVTGGNRPVQVNDL 899
                        + LGVDST+   VWAL+FLV + +IQEKLY EI N TGG RPV+V DL
Sbjct: 285  SDEIIYSMVLEIFGLGVDSTAATAVWALSFLVGEQEIQEKLYREINNRTGGQRPVKVVDL 344

Query: 900  KKMSYLQAVMRETLRMKPIGPVIFTHEAAKDTSLMGKKVGKGTRIMVNLRAIHYNSKVFP 1079
            K++ YLQAVM+ETLRMKPI P+   H AAKDT+  G+++ KGT++MVNL AIH++  VFP
Sbjct: 345  KELPYLQAVMKETLRMKPIAPLAVPHVAAKDTTFKGRRIVKGTKVMVNLYAIHHDPNVFP 404

Query: 1080 EPYKFIPERYIKEVNRDASLGDREKMESSLIAFGAGMRVCAGIDLAKIIVPFGIASLVNE 1259
             PYKF+PER++K+VN D   GD   MESSLI FGAGMR+C G++LAK +V F +AS+VNE
Sbjct: 405  APYKFMPERFLKDVNSDGRFGDINTMESSLIPFGAGMRICGGVELAKQMVAFALASMVNE 464


>sp|Q50LH3.1|C7192_ESCCA RecName: Full=(S)-stylopine synthase 1; Short=STS; AltName:
            Full=Cytochrome P450 719A2; Short=EcCYP719A2;
            Short=EcCYPB gi|63108256|dbj|BAD98250.1| stylopine
            synthase [Eschscholzia californica]
          Length = 495

 Score =  389 bits (999), Expect = e-105
 Identities = 190/418 (45%), Positives = 282/418 (67%), Gaps = 2/418 (0%)
 Frame = +3

Query: 3    IGNLHQLRGDDFHVRMANFAKVHGGIFTLWIGSWHPVIIINDIASAWEVLVTXXXXXXXX 182
            IGN+H L G    V + N AKVHG + T+WIGSW PVI+++DI  AWEVLV         
Sbjct: 49   IGNMHLLGGTALQVVLHNLAKVHGSVMTIWIGSWRPVIVVSDIERAWEVLVNKSSDYSAR 108

Query: 183  XXXXXXXXXVNSAGNEKYTNIAESDVGPFWTNLRKGLQSVALGPLNVTSQTHLQERSMHR 362
                     +    +  +  I+ SD GP WTNLRKGLQ+VAL P N+ +Q   QE+ M +
Sbjct: 109  DMPD-----ITKIISADWKTISTSDSGPHWTNLRKGLQNVALSPHNLAAQFQFQEKDMTK 163

Query: 363  LIKSMQQKALQQNGILKPLDYLKEESIRLLSVLIFGQDFSDENFVVRMNRILYDLVRIDQ 542
            +I++++++A   NGI+KPLD++K+ ++RL+S L+FGQDF+++ +V  M+  + +L+R+  
Sbjct: 164  MIQTLEEEARNNNGIVKPLDHMKKATLRLISRLVFGQDFNNDKYVDDMHLAIEELIRVSG 223

Query: 543  ITSLSDAFHIAKYLPSSKKVIRELDDVMEQAASLIIPYISTSKTPPANTYLNFLKSQDYX 722
               L++AF+ AKYLPS KK +RE+++   +  +L+ P++S +  PP NTYL+FL+SQ Y 
Sbjct: 224  YARLAEAFYYAKYLPSHKKAVREVEEAQRRVQNLVSPFLSLN--PPTNTYLHFLRSQKYD 281

Query: 723  XXXXXXXXXXXYTLGVDSTSEAIVWALTFLVRDPKIQEKLYHEIKNVTGGN--RPVQVND 896
                       Y LGVDSTS    WAL FL+R+P +QEKLY E+++    N  R ++V D
Sbjct: 282  DEVIIFAIFEAYLLGVDSTSLTTAWALAFLIREPNVQEKLYQELESFASKNDRRILKVED 341

Query: 897  LKKMSYLQAVMRETLRMKPIGPVIFTHEAAKDTSLMGKKVGKGTRIMVNLRAIHYNSKVF 1076
            + K+ YLQAV++ET+RMKPI P+   H+A +DTSLMGKK+ KGTR+MVN+ A+H+N  VF
Sbjct: 342  INKLQYLQAVIKETMRMKPIAPLAIPHKACRDTSLMGKKIDKGTRVMVNIFALHHNKNVF 401

Query: 1077 PEPYKFIPERYIKEVNRDASLGDREKMESSLIAFGAGMRVCAGIDLAKIIVPFGIASL 1250
             +P+KF+PER++K  ++DA   + + ME SL+ F AGMR+CAG++L K+   F +A+L
Sbjct: 402  NDPFKFMPERFMKVDSQDA---NGKAMEQSLLPFSAGMRICAGMELGKLQFSFALANL 456


>sp|B1NF19.1|C719D_ARGME RecName: Full=(S)-stylopine synthase; Short=STS; AltName:
            Full=Cytochrome P450 719A13 gi|148841092|gb|ABR14721.1|
            stylopine synthase [Argemone mexicana]
          Length = 504

 Score =  387 bits (995), Expect = e-105
 Identities = 193/420 (45%), Positives = 280/420 (66%), Gaps = 2/420 (0%)
 Frame = +3

Query: 3    IGNLHQLRGDDFHVRMANFAKVHGGIFTLWIGSWHPVIIINDIASAWEVLVTXXXXXXXX 182
            IGN++ L G   HV + N AK +G + T+WIGSW PVI+++DI  AWEVLV         
Sbjct: 58   IGNMNILGGTALHVVLHNLAKTYGNVMTIWIGSWRPVIVVSDIDRAWEVLVNKSSDYSAR 117

Query: 183  XXXXXXXXXVNSAGNEKYTNIAESDVGPFWTNLRKGLQSVALGPLNVTSQTHLQERSMHR 362
                     +       +  I+ SD GPFWTNLRKGLQ+VAL P N++SQ+  QER + +
Sbjct: 118  DMPE-----ITKLATADWKTISSSDSGPFWTNLRKGLQNVALSPQNLSSQSKFQERDIIK 172

Query: 363  LIKSMQQKALQQNGILKPLDYLKEESIRLLSVLIFGQDFSDENFVVRMNRILYDLVRIDQ 542
             I++++++A   NGI+KPLD+LK+  +RL+S LI+GQDF ++ +V  M+  + +L+R+  
Sbjct: 173  TIQNLKEEAKMNNGIVKPLDHLKKAMVRLISRLIYGQDFDNDEYVEEMHHTIEELIRVSG 232

Query: 543  ITSLSDAFHIAKYLPSSKKVIRELDDVMEQAASLIIPYISTSKTPPANTYLNFLKSQDYX 722
               L++AF+ AKYLPS KK +RE+    ++  +L+ P +S +   P NTYL+FL+SQ+Y 
Sbjct: 233  YARLAEAFYYAKYLPSHKKAVREVLQANQRVQNLVRPLLSLNS--PTNTYLHFLRSQNYE 290

Query: 723  XXXXXXXXXXXYTLGVDSTSEAIVWALTFLVRDPKIQEKLYHEIKNVTGGN--RPVQVND 896
                       Y LGVDSTS    WAL +L+R+P +QEKLY E+KN T  N  + V+  D
Sbjct: 291  DEVIIFAIFEAYLLGVDSTSSTTAWALAYLIREPNVQEKLYEELKNFTNDNDRKMVKFED 350

Query: 897  LKKMSYLQAVMRETLRMKPIGPVIFTHEAAKDTSLMGKKVGKGTRIMVNLRAIHYNSKVF 1076
            L K+ YLQAV++ET+RMKPI P+   H+A ++TSLMG+KV +GTR+MVN+ A+H+N  V+
Sbjct: 351  LNKLQYLQAVVKETMRMKPIAPLAIPHKACRETSLMGRKVNQGTRVMVNIYALHHNQNVW 410

Query: 1077 PEPYKFIPERYIKEVNRDASLGDREKMESSLIAFGAGMRVCAGIDLAKIIVPFGIASLVN 1256
             EPYKF PER++++ N+D    D + ME SL+ F AGMR+CAG++L K+   F +A+LVN
Sbjct: 411  KEPYKFNPERFLQK-NQDGV--DGKAMEQSLLPFSAGMRICAGMELGKLQFSFALANLVN 467


>gb|AGL76711.1| (S)-canadine synthase, partial [Coptis chinensis]
          Length = 491

 Score =  385 bits (989), Expect = e-104
 Identities = 196/418 (46%), Positives = 267/418 (63%)
 Frame = +3

Query: 3    IGNLHQLRGDDFHVRMANFAKVHGGIFTLWIGSWHPVIIINDIASAWEVLVTXXXXXXXX 182
            IGNLHQL  D  HV +A  AKVHG + T+WIGSW PVI+I+D+  AWEVLV         
Sbjct: 46   IGNLHQLGDDVLHVALAKLAKVHGSMMTIWIGSWRPVIVISDLEKAWEVLVNKSADYGAR 105

Query: 183  XXXXXXXXXVNSAGNEKYTNIAESDVGPFWTNLRKGLQSVALGPLNVTSQTHLQERSMHR 362
                     +    +  +  I+ SD GPFW N+RKGLQS A+GP NV +Q   QER M R
Sbjct: 106  DMPE-----ITKIASASWHTISTSDAGPFWQNVRKGLQSGAMGPFNVAAQNQHQERGMKR 160

Query: 363  LIKSMQQKALQQNGILKPLDYLKEESIRLLSVLIFGQDFSDENFVVRMNRILYDLVRIDQ 542
            LIK+M  +A   NGI+KPLD++K+ ++RLL+ LIFGQ+F D  F+  M+  + D++RI  
Sbjct: 161  LIKAMSDEAANNNGIVKPLDHIKKNTVRLLTRLIFGQNFDDNKFIESMHYEIEDIIRISG 220

Query: 543  ITSLSDAFHIAKYLPSSKKVIRELDDVMEQAASLIIPYISTSKTPPANTYLNFLKSQDYX 722
               L++AF+ AKYLPS KK  RE   V  +   L+ P +S++  PP N+YL FL SQ++ 
Sbjct: 221  YARLAEAFYYAKYLPSHKKAEREAFLVKCRVQELVRPLLSSN--PPTNSYLYFLLSQNFE 278

Query: 723  XXXXXXXXXXXYTLGVDSTSEAIVWALTFLVRDPKIQEKLYHEIKNVTGGNRPVQVNDLK 902
                       Y LGVDSTS    WAL +L+R+   QEKLY +I+   G    V++ D+ 
Sbjct: 279  EEVIIFCIFELYLLGVDSTSSTTTWALAYLIREQGAQEKLYQDIRMTLGDVDLVKIEDVN 338

Query: 903  KMSYLQAVMRETLRMKPIGPVIFTHEAAKDTSLMGKKVGKGTRIMVNLRAIHYNSKVFPE 1082
            K+ YLQ V++ET+RMKPI P+   H+ AK+T+LMG KV KGTRIMVNL A+H+N  ++P+
Sbjct: 339  KLKYLQGVVKETMRMKPIAPLAIPHKTAKETTLMGTKVAKGTRIMVNLYALHHNQNIWPD 398

Query: 1083 PYKFIPERYIKEVNRDASLGDREKMESSLIAFGAGMRVCAGIDLAKIIVPFGIASLVN 1256
            PYKF+PER+++     A     + ME S + F AGMR+CAG+DL K+   F +A+LVN
Sbjct: 399  PYKFMPERFLEGATGTAY---NKAMEQSFLPFSAGMRICAGMDLGKLQFAFALANLVN 453


>gb|AHF65153.1| stylopine synthase, partial [synthetic construct]
          Length = 511

 Score =  384 bits (987), Expect = e-104
 Identities = 190/420 (45%), Positives = 281/420 (66%), Gaps = 2/420 (0%)
 Frame = +3

Query: 3    IGNLHQLRGDDFHVRMANFAKVHGGIFTLWIGSWHPVIIINDIASAWEVLVTXXXXXXXX 182
            IGN+H L G    V + N AK+HG + T+WIGSW PVI+++DI  AWEVLV         
Sbjct: 63   IGNMHVLGGTALQVVLHNLAKIHGNVMTIWIGSWRPVIVVSDIDRAWEVLVNKSSDYSAR 122

Query: 183  XXXXXXXXXVNSAGNEKYTNIAESDVGPFWTNLRKGLQSVALGPLNVTSQTHLQERSMHR 362
                     +    +  +  I+ SD GP W+NLRKGLQ+VAL P N+ +Q+  QE+ + +
Sbjct: 123  DMPE-----ITKIISADWKTISTSDSGPGWSNLRKGLQNVALSPHNLAAQSQFQEKDITK 177

Query: 363  LIKSMQQKALQQNGILKPLDYLKEESIRLLSVLIFGQDFSDENFVVRMNRILYDLVRIDQ 542
            +I+S++++A   NGI+KP+D+LK+ ++RL+S LIFGQDF D+ +V  M+  + +L+R+  
Sbjct: 178  MIQSLKKEAASNNGIVKPIDHLKKATLRLISRLIFGQDFDDDKYVDDMHHAIEELIRVSG 237

Query: 543  ITSLSDAFHIAKYLPSSKKVIRELDDVMEQAASLIIPYISTSKTPPANTYLNFLKSQDYX 722
               L++AF+ AKYLPS KK +R++++  ++   L+ P++S +  PP NTYL+FL SQ Y 
Sbjct: 238  YAQLAEAFYYAKYLPSHKKAVRDVEEANQRVKKLVRPFLSLN--PPTNTYLHFLNSQKYD 295

Query: 723  XXXXXXXXXXXYTLGVDSTSEAIVWALTFLVRDPKIQEKLYHEIKNVTGGN--RPVQVND 896
                       Y LGVDSTS    WAL FL+R+P +Q+KLY E+KN+T  N    V+V D
Sbjct: 296  EEVIIFAIFEAYLLGVDSTSLTTAWALAFLIREPVVQDKLYQELKNLTAKNDCEIVKVED 355

Query: 897  LKKMSYLQAVMRETLRMKPIGPVIFTHEAAKDTSLMGKKVGKGTRIMVNLRAIHYNSKVF 1076
            L K+ YLQAV++ET+RMKPI P+   H+A +DTSL G K+ +GT++MVN+ A+H+N KV+
Sbjct: 356  LNKLQYLQAVLKETMRMKPIAPLAIPHKACRDTSLKGNKIDQGTQVMVNIYALHHNEKVW 415

Query: 1077 PEPYKFIPERYIKEVNRDASLGDREKMESSLIAFGAGMRVCAGIDLAKIIVPFGIASLVN 1256
             EP+KF+PER+++   +D   G  + ME SL+ F AGMR+CAG++L K+   F +A+LVN
Sbjct: 416  KEPFKFMPERFLQ--TQDVVNG--KGMEQSLLPFSAGMRICAGMELGKLQFSFSLANLVN 471


>gb|ADB89214.1| stylopine synthase [Papaver somniferum]
          Length = 494

 Score =  384 bits (987), Expect = e-104
 Identities = 190/420 (45%), Positives = 281/420 (66%), Gaps = 2/420 (0%)
 Frame = +3

Query: 3    IGNLHQLRGDDFHVRMANFAKVHGGIFTLWIGSWHPVIIINDIASAWEVLVTXXXXXXXX 182
            IGN+H L G    V + N AK+HG + T+WIGSW PVI+++DI  AWEVLV         
Sbjct: 49   IGNMHVLGGTALQVVLHNLAKIHGNVMTIWIGSWRPVIVVSDIDRAWEVLVNKSSDYSAR 108

Query: 183  XXXXXXXXXVNSAGNEKYTNIAESDVGPFWTNLRKGLQSVALGPLNVTSQTHLQERSMHR 362
                     +    +  +  I+ SD GP W+NLRKGLQ+VAL P N+ +Q+  QE+ + +
Sbjct: 109  DMPE-----ITKIISADWKTISTSDSGPGWSNLRKGLQNVALSPHNLAAQSQFQEKDITK 163

Query: 363  LIKSMQQKALQQNGILKPLDYLKEESIRLLSVLIFGQDFSDENFVVRMNRILYDLVRIDQ 542
            +I+S++++A   NGI+KP+D+LK+ ++RL+S LIFGQDF D+ +V  M+  + +L+R+  
Sbjct: 164  MIQSLKKEAASNNGIVKPIDHLKKATLRLISRLIFGQDFDDDKYVDDMHHAIEELIRVSG 223

Query: 543  ITSLSDAFHIAKYLPSSKKVIRELDDVMEQAASLIIPYISTSKTPPANTYLNFLKSQDYX 722
               L++AF+ AKYLPS KK +R++++  ++   L+ P++S +  PP NTYL+FL SQ Y 
Sbjct: 224  YAQLAEAFYYAKYLPSHKKAVRDVEEANQRVKKLVRPFLSLN--PPTNTYLHFLNSQKYD 281

Query: 723  XXXXXXXXXXXYTLGVDSTSEAIVWALTFLVRDPKIQEKLYHEIKNVTGGN--RPVQVND 896
                       Y LGVDSTS    WAL FL+R+P +Q+KLY E+KN+T  N    V+V D
Sbjct: 282  EEVIIFAIFEAYLLGVDSTSLTTAWALAFLIREPVVQDKLYQELKNLTAKNDCEIVKVED 341

Query: 897  LKKMSYLQAVMRETLRMKPIGPVIFTHEAAKDTSLMGKKVGKGTRIMVNLRAIHYNSKVF 1076
            L K+ YLQAV++ET+RMKPI P+   H+A +DTSL G K+ +GT++MVN+ A+H+N KV+
Sbjct: 342  LNKLQYLQAVLKETMRMKPIAPLAIPHKACRDTSLKGNKIDQGTQVMVNIYALHHNEKVW 401

Query: 1077 PEPYKFIPERYIKEVNRDASLGDREKMESSLIAFGAGMRVCAGIDLAKIIVPFGIASLVN 1256
             EP+KF+PER+++   +D   G  + ME SL+ F AGMR+CAG++L K+   F +A+LVN
Sbjct: 402  KEPFKFMPERFLQ--TQDVVNG--KGMEQSLLPFSAGMRICAGMELGKLQFSFSLANLVN 457


>gb|ACO90219.1| stylopine synthase [Eschscholzia californica]
          Length = 495

 Score =  384 bits (987), Expect = e-104
 Identities = 188/418 (44%), Positives = 280/418 (66%), Gaps = 2/418 (0%)
 Frame = +3

Query: 3    IGNLHQLRGDDFHVRMANFAKVHGGIFTLWIGSWHPVIIINDIASAWEVLVTXXXXXXXX 182
            IGN+H L G    V + N AKVHG + T+WIGSW PVI+++DI  AWEVLV         
Sbjct: 49   IGNMHLLGGTALQVVLHNLAKVHGSVMTIWIGSWRPVIVVSDIERAWEVLVNKSSDYSAR 108

Query: 183  XXXXXXXXXVNSAGNEKYTNIAESDVGPFWTNLRKGLQSVALGPLNVTSQTHLQERSMHR 362
                     +    +  +  I+ SD GP WTNLRKGLQ+VAL P N+ +Q   QE+ M +
Sbjct: 109  DMPD-----ITKIISADWKTISTSDSGPHWTNLRKGLQNVALSPHNLAAQFQFQEKDMTK 163

Query: 363  LIKSMQQKALQQNGILKPLDYLKEESIRLLSVLIFGQDFSDENFVVRMNRILYDLVRIDQ 542
            +I+++Q++A   NGI+KPLD++K+ ++RL+S L+FGQDF+++ +V  M+  + +L+R+  
Sbjct: 164  MIQTLQEEARNNNGIVKPLDHMKKATLRLISRLVFGQDFNNDKYVDDMHLAIEELIRVSG 223

Query: 543  ITSLSDAFHIAKYLPSSKKVIRELDDVMEQAASLIIPYISTSKTPPANTYLNFLKSQDYX 722
               L++AF+ AKYLPS KK +RE+++   +  +L+ P++S +  PP NTYL+FL+SQ Y 
Sbjct: 224  YARLAEAFYYAKYLPSHKKAVREVEEAQRRVQNLVSPFLSLN--PPTNTYLHFLRSQKYD 281

Query: 723  XXXXXXXXXXXYTLGVDSTSEAIVWALTFLVRDPKIQEKLYHEIKNVTG--GNRPVQVND 896
                       Y LGVDSTS    WAL FL+R+  +QEKLY E+++       + ++V D
Sbjct: 282  DEVIIFAIFEAYLLGVDSTSLTTAWALAFLIRESNVQEKLYQELESFASKMDRKILKVED 341

Query: 897  LKKMSYLQAVMRETLRMKPIGPVIFTHEAAKDTSLMGKKVGKGTRIMVNLRAIHYNSKVF 1076
            + K+ YLQAV++ET+RMKPI P+   H+A +DTSLMGKK+ KGTR+MVN+ A+H+N  VF
Sbjct: 342  INKLQYLQAVIKETMRMKPIAPLAIPHKACRDTSLMGKKIDKGTRVMVNIYALHHNKNVF 401

Query: 1077 PEPYKFIPERYIKEVNRDASLGDREKMESSLIAFGAGMRVCAGIDLAKIIVPFGIASL 1250
             +P+KF+PER++K  ++DA   + + ME SL+ F AGMR+CAG++L K+   F +A+L
Sbjct: 402  NDPFKFMPERFMKVDSQDA---NGKAMEQSLLPFSAGMRICAGMELGKLQFSFALANL 456


>sp|Q948Y1.1|C719A_COPJA RecName: Full=(S)-canadine synthase; AltName:
            Full=(S)-tetrahydrocolumbamine oxidase
            (methylenedioxy-bridge-forming); AltName: Full=Cytochrome
            P450 719A1 gi|15822820|dbj|BAB68769.1| methylenedioxy
            bridge-forming enzyme [Coptis japonica]
          Length = 491

 Score =  384 bits (986), Expect = e-104
 Identities = 196/418 (46%), Positives = 265/418 (63%)
 Frame = +3

Query: 3    IGNLHQLRGDDFHVRMANFAKVHGGIFTLWIGSWHPVIIINDIASAWEVLVTXXXXXXXX 182
            IGNLHQL  D  HV +A  AKVHG + T+WIGSW PVI+I+DI  AWEVLV         
Sbjct: 46   IGNLHQLGDDVLHVALAKLAKVHGSVMTIWIGSWRPVIVISDIEKAWEVLVNKSADYGAR 105

Query: 183  XXXXXXXXXVNSAGNEKYTNIAESDVGPFWTNLRKGLQSVALGPLNVTSQTHLQERSMHR 362
                     +    +  +  I+ SD G FW N+RKGLQS A+GPLNV +Q   QER M R
Sbjct: 106  DMPE-----ITKIASASWHTISTSDAGSFWQNVRKGLQSGAMGPLNVAAQNQYQERDMKR 160

Query: 363  LIKSMQQKALQQNGILKPLDYLKEESIRLLSVLIFGQDFSDENFVVRMNRILYDLVRIDQ 542
            LIK+M  +A   NGI+KPLD++K+ ++RLL+ LIFGQ F D  F+  M+  + D++RI  
Sbjct: 161  LIKAMSDEAANNNGIVKPLDHIKKNTVRLLTRLIFGQAFDDNKFIESMHYEIEDIIRISG 220

Query: 543  ITSLSDAFHIAKYLPSSKKVIRELDDVMEQAASLIIPYISTSKTPPANTYLNFLKSQDYX 722
               L++AF+ AKYLPS KK  RE   V  +   L+ P +S+   PP N+YL FL SQ++ 
Sbjct: 221  YARLAEAFYYAKYLPSHKKAEREAFLVKCRVEELVRPLLSSK--PPTNSYLYFLLSQNFE 278

Query: 723  XXXXXXXXXXXYTLGVDSTSEAIVWALTFLVRDPKIQEKLYHEIKNVTGGNRPVQVNDLK 902
                       Y LGVDSTS    WAL +L+R+   QEKLY +I+   G    V++ D+ 
Sbjct: 279  EEVIIFCIFELYLLGVDSTSSTTTWALAYLIREQGAQEKLYQDIRMTLGDVDLVKIEDVN 338

Query: 903  KMSYLQAVMRETLRMKPIGPVIFTHEAAKDTSLMGKKVGKGTRIMVNLRAIHYNSKVFPE 1082
            K+ YLQ V++ET+RMKPI P+   H+ AK+T+LMG KV KGTRIMVNL A+H+N  ++P+
Sbjct: 339  KLKYLQGVVKETMRMKPIAPLAIPHKTAKETTLMGTKVAKGTRIMVNLYALHHNQNIWPD 398

Query: 1083 PYKFIPERYIKEVNRDASLGDREKMESSLIAFGAGMRVCAGIDLAKIIVPFGIASLVN 1256
            PYKF+PER+++    +      + ME S + F AGMR+CAG+DL K+   F +A+LVN
Sbjct: 399  PYKFMPERFLE---GETGTAYNKAMEQSFLPFSAGMRICAGMDLGKLQFAFALANLVN 453


>gb|AAU20771.1| (S)-canadine synthase [Thalictrum flavum subsp. glaucum]
          Length = 492

 Score =  381 bits (979), Expect = e-103
 Identities = 194/418 (46%), Positives = 269/418 (64%)
 Frame = +3

Query: 3    IGNLHQLRGDDFHVRMANFAKVHGGIFTLWIGSWHPVIIINDIASAWEVLVTXXXXXXXX 182
            IGNLHQL GD  HV +A  A+VHG + T+WIG+W P+I+I+DI  AWEVLV         
Sbjct: 47   IGNLHQLGGDVLHVALAKLAQVHGSVMTVWIGNWRPIIVISDIDKAWEVLVNKSSDYGAR 106

Query: 183  XXXXXXXXXVNSAGNEKYTNIAESDVGPFWTNLRKGLQSVALGPLNVTSQTHLQERSMHR 362
                     +    +  +  I+ SD G FW  +RKGLQS A+GPLN+ +Q+  QER M R
Sbjct: 107  DMPE-----ITKIASASWHTISTSDAGAFWQTVRKGLQSGAMGPLNIAAQSQFQERDMKR 161

Query: 363  LIKSMQQKALQQNGILKPLDYLKEESIRLLSVLIFGQDFSDENFVVRMNRILYDLVRIDQ 542
            LI++++ +A Q N I+KPLD++K+ ++RLL+ LIFGQ F D+ FV  M+  + D++RI  
Sbjct: 162  LIQALRDEAAQNNNIVKPLDHIKKNTVRLLTRLIFGQTFDDDKFVESMHFEIDDIIRISG 221

Query: 543  ITSLSDAFHIAKYLPSSKKVIRELDDVMEQAASLIIPYISTSKTPPANTYLNFLKSQDYX 722
               L++AF+ AKYLPS KK  RE   V  +   L+ P +S++  PP N+YL FL SQ + 
Sbjct: 222  YARLAEAFYYAKYLPSHKKAEREAYLVKCRVEDLVSPLLSSN--PPTNSYLYFLLSQRFS 279

Query: 723  XXXXXXXXXXXYTLGVDSTSEAIVWALTFLVRDPKIQEKLYHEIKNVTGGNRPVQVNDLK 902
                       Y LGVDSTS    WAL +L+R+  IQEKLY + +   G    V++ D+ 
Sbjct: 280  EEVIIFCIFELYLLGVDSTSSTTTWALAYLIREQAIQEKLYQDTRMTLGDVDLVKIEDVS 339

Query: 903  KMSYLQAVMRETLRMKPIGPVIFTHEAAKDTSLMGKKVGKGTRIMVNLRAIHYNSKVFPE 1082
            K+ YLQAV++ET+RMKPI P+   H+ AKDT+LMG KV KGTRIMVNL A+H+N  ++  
Sbjct: 340  KLKYLQAVVKETMRMKPIAPLAIPHKTAKDTTLMGSKVAKGTRIMVNLYALHHNQNIWTN 399

Query: 1083 PYKFIPERYIKEVNRDASLGDREKMESSLIAFGAGMRVCAGIDLAKIIVPFGIASLVN 1256
            PYKF+PER+++  +  AS    + ME S + F AGMR+CAG+DL K+   F +A+LVN
Sbjct: 400  PYKFMPERFLQGEDGSAS---NKAMEQSFLPFSAGMRICAGMDLGKLQFAFALANLVN 454


>gb|AFI57927.1| cytochrome P450, partial [Papaver somniferum]
          Length = 488

 Score =  381 bits (978), Expect = e-103
 Identities = 192/420 (45%), Positives = 273/420 (65%), Gaps = 2/420 (0%)
 Frame = +3

Query: 3    IGNLHQLRGDDFHVRMANFAKVHGGIFTLWIGSWHPVIIINDIASAWEVLVTXXXXXXXX 182
            IGNLH L G   HV +   A+V+G + T+WIGSW PVII++D   AWEVLV         
Sbjct: 47   IGNLHILGGTALHVVLHKLAEVYGSVMTIWIGSWKPVIIVSDFDRAWEVLVNKSSDYSAR 106

Query: 183  XXXXXXXXXVNSAGNEKYTNIAESDVGPFWTNLRKGLQSVALGPLNVTSQTHLQERSMHR 362
                     +   G   +  I+ SD GPFW  LRKGLQSVAL P ++ SQT  QER + +
Sbjct: 107  EMPE-----ITKIGTANWRTISSSDSGPFWATLRKGLQSVALSPQHLASQTAHQERDIIK 161

Query: 363  LIKSMQQKALQQNGILKPLDYLKEESIRLLSVLIFGQDFSDENFVVRMNRILYDLVRIDQ 542
            LIK+++ +A   +G++KPLD+LK+ ++RL+S LI+GQDF D+ +V  M+ ++  L+RI  
Sbjct: 162  LIKNLKDEAALNSGMVKPLDHLKKATVRLISRLIYGQDFDDDKYVEDMHDVIEFLIRISG 221

Query: 543  ITSLSDAFHIAKYLPSSKKVIRELDDVMEQAASLIIPYISTSKTPPANTYLNFLKSQDYX 722
               L++ F+ AKYLPS K+ +   ++   +  +L+ P++ ++  P  NTYL+FLKSQ Y 
Sbjct: 222  YAQLAEVFYYAKYLPSHKRAVTGAEEAKRRVIALVRPFLQSN--PATNTYLHFLKSQLYP 279

Query: 723  XXXXXXXXXXXYTLGVDSTSEAIVWALTFLVRDPKIQEKLYHEIKNVTGGNR--PVQVND 896
                       Y LGVDSTS    WAL FL+R+P +QEKLY E+KN T  N    ++V D
Sbjct: 280  EEVIIFAIFEAYLLGVDSTSSTTAWALAFLIREPSVQEKLYQELKNFTANNNRTMLKVED 339

Query: 897  LKKMSYLQAVMRETLRMKPIGPVIFTHEAAKDTSLMGKKVGKGTRIMVNLRAIHYNSKVF 1076
            + K+ YLQAV++ET+RMKPI P+   H+A KDTSLMGKKV KGT++MVN+ A+H+  KV+
Sbjct: 340  VNKLPYLQAVVKETMRMKPIAPLAIPHKACKDTSLMGKKVDKGTKVMVNIHALHHTEKVW 399

Query: 1077 PEPYKFIPERYIKEVNRDASLGDREKMESSLIAFGAGMRVCAGIDLAKIIVPFGIASLVN 1256
             EPYKF+PER++++ ++         ME SL+ F AGMR+CAG++L K+   F +A+LVN
Sbjct: 400  KEPYKFMPERFLQKHDK--------AMEQSLLPFSAGMRICAGMELGKLQFSFSLANLVN 451


>sp|Q50LH4.1|C7193_ESCCA RecName: Full=(S)-stylopine synthase 2; Short=STS; AltName:
            Full=Cytochrome P450 719A3; Short=EcCYP719A3;
            Short=EcCYPA gi|63108254|dbj|BAD98249.1| stylopine
            synthase [Eschscholzia californica]
          Length = 495

 Score =  379 bits (974), Expect = e-102
 Identities = 186/419 (44%), Positives = 278/419 (66%), Gaps = 2/419 (0%)
 Frame = +3

Query: 3    IGNLHQLRGDDFHVRMANFAKVHGGIFTLWIGSWHPVIIINDIASAWEVLVTXXXXXXXX 182
            IGN+H L G    V + N AKVHG + T+WIGSW PVI+++DI  AWEVLV         
Sbjct: 49   IGNMHLLGGTALQVVLYNLAKVHGRVMTIWIGSWRPVIVVSDIEQAWEVLVNKSSDYSAR 108

Query: 183  XXXXXXXXXVNSAGNEKYTNIAESDVGPFWTNLRKGLQSVALGPLNVTSQTHLQERSMHR 362
                     +       +  I+ SD GP W+NLRKGLQ++A+ P N+ +Q   QE+ + +
Sbjct: 109  DMPD-----ITKIVTADWRTISTSDSGPHWSNLRKGLQNIAISPNNLAAQFQFQEKDIIK 163

Query: 363  LIKSMQQKALQQNGILKPLDYLKEESIRLLSVLIFGQDFSDENFVVRMNRILYDLVRIDQ 542
            +I+ ++Q+A   NGI+KPLD+LK+ +IRL+S L+FG+DF ++ +V  M+  + +L+RI  
Sbjct: 164  MIQILEQEAKDNNGIVKPLDHLKKATIRLISRLVFGRDFEEDKYVEDMHHAIEELIRISG 223

Query: 543  ITSLSDAFHIAKYLPSSKKVIRELDDVMEQAASLIIPYISTSKTPPANTYLNFLKSQDYX 722
               L++AF+ AKYLPS +K +R ++++ +   +LI P++S +  PP NTYL+FL+SQ+Y 
Sbjct: 224  YARLAEAFYYAKYLPSHRKAVRYVEELKQIVKNLIRPFLSVN--PPTNTYLHFLRSQNYD 281

Query: 723  XXXXXXXXXXXYTLGVDSTSEAIVWALTFLVRDPKIQEKLYHEIKNVTGGN--RPVQVND 896
                       Y LGVDSTS    WAL +LVR+P +Q++L+ E+ +    N  + ++V D
Sbjct: 282  EEVVIFAIFETYLLGVDSTSSTTAWALAYLVREPSVQDRLHQELDHFAKQNDRKILKVED 341

Query: 897  LKKMSYLQAVMRETLRMKPIGPVIFTHEAAKDTSLMGKKVGKGTRIMVNLRAIHYNSKVF 1076
            + K+ YLQAV++ET+RMKPI P+   H+A KDTSLMG K+ KGTR+MVNL A+H+N  VF
Sbjct: 342  MNKLQYLQAVIKETMRMKPIAPLAIPHKACKDTSLMGNKINKGTRVMVNLYALHHNKNVF 401

Query: 1077 PEPYKFIPERYIKEVNRDASLGDREKMESSLIAFGAGMRVCAGIDLAKIIVPFGIASLV 1253
             +P+KF+PER++K  N+DA     + ME SL+ F AGMR+CAG++L K+   F +A+L+
Sbjct: 402  NDPFKFMPERFLKVDNQDAK---GKAMEQSLLPFSAGMRICAGMELGKLQFSFALANLI 457


>gb|AFB74615.1| cytochrome P450 [Papaver somniferum]
          Length = 486

 Score =  376 bits (966), Expect = e-101
 Identities = 192/420 (45%), Positives = 272/420 (64%), Gaps = 2/420 (0%)
 Frame = +3

Query: 3    IGNLHQLRGDDFHVRMANFAKVHGGIFTLWIGSWHPVIIINDIASAWEVLVTXXXXXXXX 182
            IGNLH L G   HV +   A+V+G + T+WIGSW PVII++D   AWEVLV         
Sbjct: 47   IGNLHILGGTALHVVLHKLAEVYGSVMTIWIGSWKPVIIVSDFDRAWEVLVNKSSDYSAR 106

Query: 183  XXXXXXXXXVNSAGNEKYTNIAESDVGPFWTNLRKGLQSVALGPLNVTSQTHLQERSMHR 362
                     +   G   +  I+ SD GPFW  LRKGLQSVAL P ++ SQT  QER + +
Sbjct: 107  EMPE-----ITKIGTANWRTISSSDSGPFWATLRKGLQSVALSPQHLASQTAHQERDIIK 161

Query: 363  LIKSMQQKALQQNGILKPLDYLKEESIRLLSVLIFGQDFSDENFVVRMNRILYDLVRIDQ 542
            LIK+++ +A   +G++KPLD+LK+ ++RL+S LI+GQDF D+ +V  M+ ++  L+RI  
Sbjct: 162  LIKNLKDEAA--SGMVKPLDHLKKATVRLISRLIYGQDFDDDKYVEDMHDVIEFLIRISG 219

Query: 543  ITSLSDAFHIAKYLPSSKKVIRELDDVMEQAASLIIPYISTSKTPPANTYLNFLKSQDYX 722
               L++ F+ AKYLP  K+ +   ++   +  +L+ P++ ++  P  NTYL+FLKSQ Y 
Sbjct: 220  YAQLAEVFYYAKYLPGHKRAVTGAEEAKRRVIALVRPFLQSN--PATNTYLHFLKSQLYP 277

Query: 723  XXXXXXXXXXXYTLGVDSTSEAIVWALTFLVRDPKIQEKLYHEIKNVTGGNRP--VQVND 896
                       Y LGVDSTS    WAL FL+R+P +QEKLY E+KN T  N    ++V D
Sbjct: 278  EEVIIFAIFEAYLLGVDSTSSTTAWALAFLIREPSVQEKLYQELKNFTANNNRTMLKVED 337

Query: 897  LKKMSYLQAVMRETLRMKPIGPVIFTHEAAKDTSLMGKKVGKGTRIMVNLRAIHYNSKVF 1076
            + K+ YLQAV++ET+RMKPI P+   H+A KDTSLMGKKV KGT++MVN+ A+H+  KV+
Sbjct: 338  VNKLPYLQAVVKETMRMKPIAPLAIPHKACKDTSLMGKKVDKGTKVMVNIHALHHTEKVW 397

Query: 1077 PEPYKFIPERYIKEVNRDASLGDREKMESSLIAFGAGMRVCAGIDLAKIIVPFGIASLVN 1256
             EPYKFIPER++++ ++         ME SL+ F AGMR+CAG++L K+   F +A+LVN
Sbjct: 398  KEPYKFIPERFLQKHDK--------AMEQSLLPFSAGMRICAGMELGKLQFSFSLANLVN 449


>dbj|BAG75116.1| cytochrome P450 [Eschscholzia californica]
          Length = 495

 Score =  376 bits (966), Expect = e-101
 Identities = 187/419 (44%), Positives = 274/419 (65%), Gaps = 2/419 (0%)
 Frame = +3

Query: 3    IGNLHQLRGDDFHVRMANFAKVHGGIFTLWIGSWHPVIIINDIASAWEVLVTXXXXXXXX 182
            IGN+H L G    V + N AKVHG + T+WIGSW PVI+++DI  AWEVLV         
Sbjct: 49   IGNMHLLGGTALQVVLHNLAKVHGSVMTIWIGSWRPVIVVSDIERAWEVLVNKSSDYSAR 108

Query: 183  XXXXXXXXXVNSAGNEKYTNIAESDVGPFWTNLRKGLQSVALGPLNVTSQTHLQERSMHR 362
                     +          IA  D GP W+NLRKGLQ+VAL P N+ +Q   QE+ + +
Sbjct: 109  ELPD-----IIKYNTADCRTIATCDSGPHWSNLRKGLQNVALSPNNLAAQFQFQEKDVIK 163

Query: 363  LIKSMQQKALQQNGILKPLDYLKEESIRLLSVLIFGQDFSDENFVVRMNRILYDLVRIDQ 542
            +I  ++Q+A+ +NGI+KPLD+LK+ +IRL+S L+FGQDF+D+ +V  +++ + +L+R+  
Sbjct: 164  MIDILEQEAINKNGIVKPLDHLKKATIRLISRLVFGQDFNDDKYVEDLHQAIEELIRMSG 223

Query: 543  ITSLSDAFHIAKYLPSSKKVIRELDDVMEQAASLIIPYISTSKTPPANTYLNFLKSQDYX 722
               L++AF+ AKYLPS KK IR  +   +   +L+ P++S +  PP N+YL+FL+SQ Y 
Sbjct: 224  YAQLAEAFYYAKYLPSHKKAIRHAELTKQIVTNLVRPFLSLN--PPTNSYLHFLQSQKYD 281

Query: 723  XXXXXXXXXXXYTLGVDSTSEAIVWALTFLVRDPKIQEKLYHEIKNVTGGN--RPVQVND 896
                       Y LGVDSTS    WAL +LVR+P +Q++LY+E+ N    N  + ++V  
Sbjct: 282  EEMVIFAIFETYLLGVDSTSSTTAWALAYLVREPNVQDRLYNELNNYANYNDRKILKVEV 341

Query: 897  LKKMSYLQAVMRETLRMKPIGPVIFTHEAAKDTSLMGKKVGKGTRIMVNLRAIHYNSKVF 1076
            + K+ YLQAV +ET+RMKPI P+   H+A +DTSLMG K+ KGT++MVNL A+H+N  VF
Sbjct: 342  INKLQYLQAVTKETMRMKPIAPLAIPHKACRDTSLMGTKIDKGTKVMVNLHALHHNENVF 401

Query: 1077 PEPYKFIPERYIKEVNRDASLGDREKMESSLIAFGAGMRVCAGIDLAKIIVPFGIASLV 1253
             +P+KF+PER++K  N D ++   + ME SL+ F AGMR+CAG++L K+   F +A+LV
Sbjct: 402  TDPFKFMPERFLKVNNEDVNM---KAMEQSLLPFSAGMRICAGMELGKLQFSFALANLV 457


>dbj|BAF98470.1| cytochrome P450 [Coptis japonica var. dissecta]
          Length = 491

 Score =  376 bits (965), Expect = e-101
 Identities = 193/418 (46%), Positives = 268/418 (64%)
 Frame = +3

Query: 3    IGNLHQLRGDDFHVRMANFAKVHGGIFTLWIGSWHPVIIINDIASAWEVLVTXXXXXXXX 182
            IGNLH L GD  HV +A  AKVHG + T+WIG W P+I+I+DI SAWEVLV+        
Sbjct: 46   IGNLHLLGGDLLHVTLAKLAKVHGSVMTIWIGRWRPIIVISDINSAWEVLVSKSAEYGQR 105

Query: 183  XXXXXXXXXVNSAGNEKYTNIAESDVGPFWTNLRKGLQSVALGPLNVTSQTHLQERSMHR 362
                          N     I+ SD+GPFW N+RKGLQ+ AL PLNV +QT  +E  + R
Sbjct: 106  DTPDIFKTLTVGQNN-----ISMSDIGPFWHNVRKGLQNGALSPLNVAAQTQFREEDVKR 160

Query: 363  LIKSMQQKALQQNGILKPLDYLKEESIRLLSVLIFGQDFSDENFVVRMNRILYDLVRIDQ 542
            LI  M ++AL +NGI+KPLD++K+ + RLL  LIFG  F ++ FV  +   + D++R+  
Sbjct: 161  LIHEMSREALNKNGIIKPLDHMKKNTARLLGRLIFGPTFDNDKFVESVLYEIEDVLRLSG 220

Query: 543  ITSLSDAFHIAKYLPSSKKVIRELDDVMEQAASLIIPYISTSKTPPANTYLNFLKSQDYX 722
               L++AF+ AKYLPS KKV RE      +   L+ P +S++  PP N+YL FL+SQ+Y 
Sbjct: 221  YARLTEAFYYAKYLPSQKKVAREAYLAKYRIEELMRPLLSSN--PPTNSYLYFLQSQNYS 278

Query: 723  XXXXXXXXXXXYTLGVDSTSEAIVWALTFLVRDPKIQEKLYHEIKNVTGGNRPVQVNDLK 902
                       + LGVDSTS    WAL +L+ +  +QEKL  +I+   G    V++ DL 
Sbjct: 279  KEIIIFCTFELFLLGVDSTSSTATWALAYLIHEQAVQEKLNEDIRMTIGDVDLVKIEDLS 338

Query: 903  KMSYLQAVMRETLRMKPIGPVIFTHEAAKDTSLMGKKVGKGTRIMVNLRAIHYNSKVFPE 1082
            K+ YLQAV++ET+RMKPI P+   H+ A DT+LMG KV +GT+IMVNL A+H+N  ++PE
Sbjct: 339  KLKYLQAVVKETMRMKPIAPLAIPHKTANDTTLMGTKVARGTQIMVNLYALHHNEDIWPE 398

Query: 1083 PYKFIPERYIKEVNRDASLGDREKMESSLIAFGAGMRVCAGIDLAKIIVPFGIASLVN 1256
            PYKF+PER+++  N  A   + + ME S + FGAGMR+CAG+DL K+ + F +A+LVN
Sbjct: 399  PYKFMPERFLQGENVSA---NNKAMEQSFLPFGAGMRICAGMDLGKLQIAFALANLVN 453


>dbj|BAF98471.1| cytochrome P450 [Coptis japonica var. dissecta]
          Length = 508

 Score =  366 bits (940), Expect = 1e-98
 Identities = 193/418 (46%), Positives = 264/418 (63%)
 Frame = +3

Query: 3    IGNLHQLRGDDFHVRMANFAKVHGGIFTLWIGSWHPVIIINDIASAWEVLVTXXXXXXXX 182
            IGNLHQLRG+  HV +A  AKVHGG+ T+W+GSW P+I+I+DI SAWEVLV         
Sbjct: 59   IGNLHQLRGELLHVTLAKLAKVHGGVMTIWMGSWVPIIVISDINSAWEVLVNKSADYGAR 118

Query: 183  XXXXXXXXXVNSAGNEKYTNIAESDVGPFWTNLRKGLQSVALGPLNVTSQTHLQERSMHR 362
                      +SA +    NI+ SDVGP W N+RKGLQS AL PL+V SQT  +ER M R
Sbjct: 119  EVTYLHELLRDSAMHPH--NISSSDVGPLWHNIRKGLQSGALSPLSVASQTQHRERDMKR 176

Query: 363  LIKSMQQKALQQNGILKPLDYLKEESIRLLSVLIFGQDFSDENFVVRMNRILYDLVRIDQ 542
            ++  M ++ +  NG +KPL ++K  + RLL  LIFG  F+D  F+  M   + D +R   
Sbjct: 177  VVHEMSREIVNNNGTIKPLVHIKNSTARLLGRLIFGPSFNDSKFIESMLYEIEDFIRTSS 236

Query: 543  ITSLSDAFHIAKYLPSSKKVIRELDDVMEQAASLIIPYISTSKTPPANTYLNFLKSQDYX 722
             TSL+++F+ AKYLPS +K  RE      +   L+ P +S+   PP N YL FL SQ+  
Sbjct: 237  YTSLTNSFYYAKYLPSQRKATREAKLGKYRIEELVRPLLSSK--PPTNAYLYFLLSQNLS 294

Query: 723  XXXXXXXXXXXYTLGVDSTSEAIVWALTFLVRDPKIQEKLYHEIKNVTGGNRPVQVNDLK 902
                       + LGVDS S    WAL +++R+ + QEKLY +I+   G    V++ D+ 
Sbjct: 295  EEVTIFCIFELFLLGVDSASSTTTWALAYMIREQEAQEKLYQDIRMTIGDVDLVKIEDVN 354

Query: 903  KMSYLQAVMRETLRMKPIGPVIFTHEAAKDTSLMGKKVGKGTRIMVNLRAIHYNSKVFPE 1082
            K+ YLQ+V++ET+RMKPI P+   H A KDT+LMG K+ KGTR+MVNL A+H+   V+ E
Sbjct: 355  KLKYLQSVVKETMRMKPIAPLALPHNAGKDTTLMGTKIVKGTRVMVNLYALHHYEDVWLE 414

Query: 1083 PYKFIPERYIKEVNRDASLGDREKMESSLIAFGAGMRVCAGIDLAKIIVPFGIASLVN 1256
            P KF+PERY++    D S+   + ME SL+ FGAGMR+CAG+DL K+ V F +A+LVN
Sbjct: 415  PSKFMPERYLQ--GEDGSV-THKAMEQSLLPFGAGMRICAGMDLGKLQVAFVLANLVN 469


>dbj|BAG75114.1| cytochrome P450 [Eschscholzia californica]
          Length = 495

 Score =  357 bits (915), Expect = 8e-96
 Identities = 184/420 (43%), Positives = 270/420 (64%), Gaps = 4/420 (0%)
 Frame = +3

Query: 3    IGNLHQLRGDD-FHVRMANFAKVHGGIFTLWIGSWHPVIIINDIASAWEVLVTXXXXXXX 179
            IGN+H L G     V + N AKV+GG+ T+WIGSW PVII++DI  AWEVLV        
Sbjct: 49   IGNMHLLGGTKALQVILHNLAKVYGGVMTIWIGSWRPVIIVSDIERAWEVLVNKSSDYSA 108

Query: 180  XXXXXXXXXXVNSAGNEKYTNIAESDVGPFWTNLRKGLQSVALGPLNVTSQTHLQERSMH 359
                        +A N  +  IA  D GP W+NLRKGLQ+VAL P N+ +Q   QE+ + 
Sbjct: 109  RELPEIIKY---NAAN--FRTIATCDSGPHWSNLRKGLQNVALSPHNLAAQFQFQEKDIT 163

Query: 360  RLIKSMQQKALQQNGILKPLDYLKEESIRLLSVLIFGQDFSDENFVVRMNRILYDLVRID 539
            ++I++++ +A   NGI++PLD+LK+ +IRL+S LIFGQDF ++ +V +++  + +L+R+ 
Sbjct: 164  KMIQNLEVEAKNNNGIVQPLDHLKKATIRLISRLIFGQDFDEDTYVEKLHHTIDELIRMS 223

Query: 540  QITSLSDAFHIAKYLPSSKKVIRELDDVMEQAASLIIPYISTSKTPPANTYLNFLKSQDY 719
                L++AF+ A+YLP+ KK +       +    L+ P++S +  PP N+YL+FL+SQ+Y
Sbjct: 224  GYAQLAEAFYYARYLPNHKKAVNHAAKTKQIVTHLMRPFLSLN--PPTNSYLHFLQSQNY 281

Query: 720  XXXXXXXXXXXXYTLGVDSTSEAIVWALTFLVRDPKIQEKLYHEIKNVTGGN--RPVQVN 893
                        Y LGVDSTS    WAL +LVR+P +QE LY E+ N    N  + ++V 
Sbjct: 282  DEELIIFSIFEVYLLGVDSTSSTTAWALAYLVREPNVQETLYQELDNFAKQNDRKILKVE 341

Query: 894  DLKKMSYLQAVMRETLRMKPIGPVIFTHEAAKDTSLMGKKVGKGTRIMVNLRAIHYNSKV 1073
            D+ K+ YLQAV +ET+RMKPI P+   H+A++DT+LMGKKV KGT++MVNL A+H+N  V
Sbjct: 342  DINKLQYLQAVTKETMRMKPIAPLAIPHKASRDTTLMGKKVEKGTKVMVNLHALHHNENV 401

Query: 1074 FPEPYKFIPERYIKEVNRDASLGDREK-MESSLIAFGAGMRVCAGIDLAKIIVPFGIASL 1250
            F +PYKF+PER++K        G + K ME S + F AGMR+C G+++ K+   F +A+L
Sbjct: 402  FNDPYKFMPERFLKSYQ-----GAKAKAMEQSYLPFSAGMRICGGMEVGKLQFGFALANL 456


>dbj|BAG75115.1| cytochrome P450 [Eschscholzia californica]
          Length = 494

 Score =  355 bits (910), Expect = 3e-95
 Identities = 178/420 (42%), Positives = 265/420 (63%), Gaps = 3/420 (0%)
 Frame = +3

Query: 3    IGNLHQLRGDD-FHVRMANFAKVHGGIFTLWIGSWHPVIIINDIASAWEVLVTXXXXXXX 179
            IGN+H L G     V + N +KVHG + T+WIG W PVI++++I   WEVLV        
Sbjct: 49   IGNMHLLGGSKALQVILHNLSKVHGSVMTIWIGRWRPVIVVSNIERVWEVLVNKSSDYSG 108

Query: 180  XXXXXXXXXXVNSAGNEKYTNIAESDVGPFWTNLRKGLQSVALGPLNVTSQTHLQERSMH 359
                      V    +  +  I+ SD GP WTNLRKGLQ+VAL P ++ +Q   QE+ + 
Sbjct: 109  RYVPD-----VIKFVSADFRTISTSDSGPHWTNLRKGLQNVALSPNSLAAQFQFQEKDII 163

Query: 360  RLIKSMQQKALQQNGILKPLDYLKEESIRLLSVLIFGQDFSDENFVVRMNRILYDLVRID 539
            ++   ++++A    GI+KPLD+LK+ ++RL+S L+FG +F+D+ +V  M+  + +L+++ 
Sbjct: 164  KMTDILEREARNNKGIVKPLDHLKKATVRLISRLVFGPNFNDDQYVEDMHNTIDELIQMS 223

Query: 540  QITSLSDAFHIAKYLPSSKKVIRELDDVMEQAASLIIPYISTSKTPPANTYLNFLKSQDY 719
                L++AF+ AKYLPS +K +R  +   +    LI PYIS S  PP NTYL+FL+SQ+Y
Sbjct: 224  SYAQLAEAFYYAKYLPSHRKAVRHFEQTKQIVKKLIRPYISVS--PPPNTYLHFLQSQNY 281

Query: 720  XXXXXXXXXXXXYTLGVDSTSEAIVWALTFLVRDPKIQEKLYHEIKNVTGGN--RPVQVN 893
                        Y LGVDSTS    WAL FL+R+P +QEKLY E+KN    N    ++V 
Sbjct: 282  DEEVVIFAIFEAYLLGVDSTSSTTTWALAFLIREPNVQEKLYQELKNFAEQNDREIMKVE 341

Query: 894  DLKKMSYLQAVMRETLRMKPIGPVIFTHEAAKDTSLMGKKVGKGTRIMVNLRAIHYNSKV 1073
            D+ K+ YLQAV +ET+RMKP+ P+   H+A ++TSLMG  + KGT++MVN+ ++H+N  V
Sbjct: 342  DINKLQYLQAVTKETMRMKPVAPLAIPHKACRETSLMGMPIDKGTKVMVNIHSLHHNENV 401

Query: 1074 FPEPYKFIPERYIKEVNRDASLGDREKMESSLIAFGAGMRVCAGIDLAKIIVPFGIASLV 1253
            F +P+ F+PER++K  N++      + ME S + F AGMR+CAGI+L K+   F +A+LV
Sbjct: 402  FSDPFTFMPERFLKVDNQNV-----KAMEQSYLPFSAGMRICAGIELGKLHFGFALANLV 456