BLASTX 2.2.25 [Feb-01-2011]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= Papaver25_contig00001687
         (1072 letters)

Database: ./nr 
           38,876,450 sequences; 13,856,398,315 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gb|ACO90224.1| putative (S)-N-methylcoclaurine 3'-hydroxylase [P...   537   e-150
gb|AAF05621.1|AF191772_1 (S)-N-methylcoclaurine 3'-hydroxylase [...   536   e-150
gb|AAF61400.1|AF134590_1 (S)-N-methylcoclaurine 3'-hydroxylase [...   535   e-149
gb|AFK73713.1| cytochrome P450 [Papaver somniferum]                   502   e-139
sp|O64899.1|C80B1_ESCCA RecName: Full=(S)-N-methylcoclaurine 3'-...   479   e-133
sp|O64900.1|C80B2_ESCCA RecName: Full=(S)-N-methylcoclaurine 3'-...   477   e-132
sp|Q9FXW4.1|C80B2_COPJA RecName: Full=Probable (S)-N-methylcocla...   442   e-121
gb|ABS19627.1| (S)-N-methylcoclaurine-3'-hydroxylase [Coptis chi...   433   e-119
gb|AAU20767.1| (S)-N-methylcoclaurine 3'-hydroxylase [Thalictrum...   420   e-115
emb|CBI31830.3| unnamed protein product [Vitis vinifera]              277   6e-72
ref|XP_002274562.1| PREDICTED: probable (S)-N-methylcoclaurine 3...   277   6e-72
emb|CAN62647.1| hypothetical protein VITISV_013219 [Vitis vinifera]   276   8e-72
dbj|BAF80448.1| corytuberine synthase [Coptis japonica var. diss...   271   4e-70
ref|XP_002274530.1| PREDICTED: (S)-N-methylcoclaurine 3'-hydroxy...   264   5e-68
ref|XP_006358914.1| PREDICTED: probable (S)-N-methylcoclaurine 3...   260   8e-67
ref|XP_002510830.1| (S)-N-methylcoclaurine 3'-hydroxylase isozym...   258   3e-66
ref|XP_002513347.1| (S)-N-methylcoclaurine 3'-hydroxylase isozym...   257   7e-66
ref|XP_002274586.2| PREDICTED: (S)-N-methylcoclaurine 3'-hydroxy...   255   3e-65
emb|CAN70170.1| hypothetical protein VITISV_006874 [Vitis vinifera]   255   3e-65
ref|XP_006358915.1| PREDICTED: probable (S)-N-methylcoclaurine 3...   252   2e-64

>gb|ACO90224.1| putative (S)-N-methylcoclaurine 3'-hydroxylase [Papaver bracteatum]
          Length = 486

 Score =  537 bits (1383), Expect = e-150
 Identities = 267/333 (80%), Positives = 297/333 (89%)
 Frame = -1

Query: 1000 SLFYLIFRDSSXXXXXXXXXXXPIVGNLLQLGEKPHSQFAQLAGTYGDLFTLKLGTQTVV 821
            +  YLIFRDSS           PIVGNLLQLGEKPHSQFA+LA TYGDLFTLKLG++TVV
Sbjct: 14   TFLYLIFRDSSPKGLPPGPKPWPIVGNLLQLGEKPHSQFAELAKTYGDLFTLKLGSETVV 73

Query: 820  VASTPLAASEILKTHDRVLSGRYVFQSFRIKNHVENCMVWSDCNETWKSLRKVCRTELFT 641
            VASTPLAASEILKTHDRVLSGRYVFQSFR+K HVEN +VWS+CNETWK LRKVCR ELFT
Sbjct: 74   VASTPLAASEILKTHDRVLSGRYVFQSFRVKEHVENSIVWSECNETWKKLRKVCRAELFT 133

Query: 640  RKMIESQAQVRECKAMELVEYLRKHQGNEVKIVEVIFATLVNIFGNLIFSQNIFKLSDEN 461
            +KMIESQA++RE KAME+VE+L+++QG+EVKIVEV+F TLVNIFGNLIFSQNIFKL DE+
Sbjct: 134  QKMIESQAEIRESKAMEMVEFLKRNQGSEVKIVEVVFGTLVNIFGNLIFSQNIFKLGDES 193

Query: 460  SGSVEMKEQIWRLLELGNSTNPADYFPFLGSLDLLGQRKDVADSLQEIYGVWGPILTEKK 281
            SGSVEMKE +WR+LELGNSTNPADYFPFLG  DL GQRKDVAD LQ IY VWG +L E+K
Sbjct: 194  SGSVEMKEHLWRMLELGNSTNPADYFPFLGRFDLFGQRKDVADCLQGIYSVWGAMLKERK 253

Query: 280  LAKQHNTNTTNDFVDLLLDSGLNDQQINALLMEIFGAGTETSASTIEWALAELIKNPELT 101
            +AK HN +  NDFV++LLDSGL+DQQINALLMEIFGAGTETSASTIEWAL+EL KNPE+T
Sbjct: 254  IAKLHNNSKKNDFVEILLDSGLDDQQINALLMEIFGAGTETSASTIEWALSELTKNPEVT 313

Query: 100  ANIRSELLSVVGKRTVKESDIPNMPYLQAFVKE 2
            AN+RSELLSVVGKR VKESDIPNMPYLQAFVKE
Sbjct: 314  ANMRSELLSVVGKRPVKESDIPNMPYLQAFVKE 346


>gb|AAF05621.1|AF191772_1 (S)-N-methylcoclaurine 3'-hydroxylase [Papaver somniferum]
          Length = 481

 Score =  536 bits (1382), Expect = e-150
 Identities = 268/333 (80%), Positives = 295/333 (88%)
 Frame = -1

Query: 1000 SLFYLIFRDSSXXXXXXXXXXXPIVGNLLQLGEKPHSQFAQLAGTYGDLFTLKLGTQTVV 821
            +  YLIFRDSS           PIVGNLLQLGEKPHSQFAQLA TYGDLF+LKLG++TVV
Sbjct: 9    TFLYLIFRDSSPKGLPPGPKPWPIVGNLLQLGEKPHSQFAQLAETYGDLFSLKLGSETVV 68

Query: 820  VASTPLAASEILKTHDRVLSGRYVFQSFRIKNHVENCMVWSDCNETWKSLRKVCRTELFT 641
            VASTPLAASEILKTHDRVLSGRYVFQSFR+K HVEN +VWS+CNETWK LRKVCRTELFT
Sbjct: 69   VASTPLAASEILKTHDRVLSGRYVFQSFRVKEHVENSIVWSECNETWKKLRKVCRTELFT 128

Query: 640  RKMIESQAQVRECKAMELVEYLRKHQGNEVKIVEVIFATLVNIFGNLIFSQNIFKLSDEN 461
            +KMIESQA+VRE KAME+VEYL+K+ GNEVKI EV+F TLVNIFGNLIFSQNIFKL DE+
Sbjct: 129  QKMIESQAEVRESKAMEMVEYLKKNVGNEVKIAEVVFGTLVNIFGNLIFSQNIFKLGDES 188

Query: 460  SGSVEMKEQIWRLLELGNSTNPADYFPFLGSLDLLGQRKDVADSLQEIYGVWGPILTEKK 281
            SGSVEMKE +WR+LELGNSTNPADYFPFLG  DL GQ KDVAD LQ IY VWG +L E+K
Sbjct: 189  SGSVEMKEHLWRMLELGNSTNPADYFPFLGKFDLFGQSKDVADCLQGIYSVWGAMLKERK 248

Query: 280  LAKQHNTNTTNDFVDLLLDSGLNDQQINALLMEIFGAGTETSASTIEWALAELIKNPELT 101
            +AKQHN +  NDFV++LLDSGL+DQQINALLMEIFGAGTETSASTIEWAL+EL KNP++T
Sbjct: 249  IAKQHNNSKKNDFVEILLDSGLDDQQINALLMEIFGAGTETSASTIEWALSELTKNPQVT 308

Query: 100  ANIRSELLSVVGKRTVKESDIPNMPYLQAFVKE 2
            AN+R ELLSVVGKR VKESDIPNMPYLQAFVKE
Sbjct: 309  ANMRLELLSVVGKRPVKESDIPNMPYLQAFVKE 341


>gb|AAF61400.1|AF134590_1 (S)-N-methylcoclaurine 3'-hydroxylase [Papaver somniferum]
          Length = 481

 Score =  535 bits (1377), Expect = e-149
 Identities = 267/333 (80%), Positives = 294/333 (88%)
 Frame = -1

Query: 1000 SLFYLIFRDSSXXXXXXXXXXXPIVGNLLQLGEKPHSQFAQLAGTYGDLFTLKLGTQTVV 821
            +  YLIFRDSS           PIVGNLLQLGEKPHSQFAQLA TYGDLF+LKLG++TVV
Sbjct: 9    TFLYLIFRDSSPKGLPPGPKPWPIVGNLLQLGEKPHSQFAQLAETYGDLFSLKLGSETVV 68

Query: 820  VASTPLAASEILKTHDRVLSGRYVFQSFRIKNHVENCMVWSDCNETWKSLRKVCRTELFT 641
            VASTPLAASEILKTHDRVLSGRYVFQSFR+K HVEN +VWS+CNETWK LRKVCRT+LFT
Sbjct: 69   VASTPLAASEILKTHDRVLSGRYVFQSFRVKEHVENSIVWSECNETWKKLRKVCRTDLFT 128

Query: 640  RKMIESQAQVRECKAMELVEYLRKHQGNEVKIVEVIFATLVNIFGNLIFSQNIFKLSDEN 461
            +KMIESQA+VRE KAME+VEYL+K+ GNEVKI EV+F TLVNIFGNLIFSQNIFKL DE+
Sbjct: 129  QKMIESQAEVRESKAMEMVEYLKKNVGNEVKIAEVVFGTLVNIFGNLIFSQNIFKLGDES 188

Query: 460  SGSVEMKEQIWRLLELGNSTNPADYFPFLGSLDLLGQRKDVADSLQEIYGVWGPILTEKK 281
            SGSVEMKE +WR+LELGNSTNPADYFPFLG  DL GQ KDVAD LQ IY VWG +L E K
Sbjct: 189  SGSVEMKEHLWRMLELGNSTNPADYFPFLGKFDLFGQSKDVADCLQGIYSVWGAMLKESK 248

Query: 280  LAKQHNTNTTNDFVDLLLDSGLNDQQINALLMEIFGAGTETSASTIEWALAELIKNPELT 101
            +AKQHN +  NDFV++LLDSGL+DQQINALLMEIFGAGTETSASTIEWAL+EL KNP++T
Sbjct: 249  IAKQHNNSKKNDFVEILLDSGLDDQQINALLMEIFGAGTETSASTIEWALSELTKNPQVT 308

Query: 100  ANIRSELLSVVGKRTVKESDIPNMPYLQAFVKE 2
            AN+R ELLSVVGKR VKESDIPNMPYLQAFVKE
Sbjct: 309  ANMRLELLSVVGKRPVKESDIPNMPYLQAFVKE 341


>gb|AFK73713.1| cytochrome P450 [Papaver somniferum]
          Length = 440

 Score =  502 bits (1292), Expect = e-139
 Identities = 251/334 (75%), Positives = 290/334 (86%), Gaps = 1/334 (0%)
 Frame = -1

Query: 1000 SLFYLIFRDSSXXXXXXXXXXXPIVGNLLQLGEKPHSQFAQLAGTYGDLFTLKLGTQTVV 821
            +  YLI R+SS           PIVGNLLQLGEKPHSQFAQLA TYGDLFTLKLGTQTVV
Sbjct: 15   TFLYLIVRESSPNGLPPGPKPWPIVGNLLQLGEKPHSQFAQLAETYGDLFTLKLGTQTVV 74

Query: 820  VASTPLAASEILKTHDRVLSGRYVFQSFRIKNHVENCMVWSDCNETWKSLRKVCRTELFT 641
            VASTPLAASE+LK HDR L GRYVFQSFR+KNHVEN +VW++CNETWK LRKVCRT+LFT
Sbjct: 75   VASTPLAASEVLKAHDRTLCGRYVFQSFRVKNHVENSIVWNECNETWKKLRKVCRTQLFT 134

Query: 640  RKMIESQAQVRECKAMELVEYLRKHQGNEVKIVEVIFATLVNIFGNLIFSQNIFKLSDEN 461
            +KMIE+QA+VRE K ME+V+YL+K++G EVKIVEVIF TLVN+FGNLIFSQ+IFKL DE+
Sbjct: 135  QKMIENQAEVREIKTMEMVKYLKKNEGIEVKIVEVIFGTLVNMFGNLIFSQDIFKLGDES 194

Query: 460  SGSVEMKEQIWRLLELGNSTNPADYFPFLGSLDLLGQRKDVADSLQEIYGVWGPILTEKK 281
            SGS+EMK+ IWR+LELGNS NP DY P LGSLDL GQRKDVAD LQ +YGVWG +L E++
Sbjct: 195  SGSLEMKQHIWRMLELGNSANPGDYVPLLGSLDLFGQRKDVADCLQGVYGVWGAMLKERR 254

Query: 280  LAK-QHNTNTTNDFVDLLLDSGLNDQQINALLMEIFGAGTETSASTIEWALAELIKNPEL 104
            +AK Q N +T NDFVD+LLDSGL+DQQIN+LL+++F AGTET+ASTIEWAL EL KNP++
Sbjct: 255  IAKRQINGDTKNDFVDVLLDSGLDDQQINSLLLDMFSAGTETTASTIEWALTELTKNPQV 314

Query: 103  TANIRSELLSVVGKRTVKESDIPNMPYLQAFVKE 2
            TA+IRSELLSVVGKR VKESDI N+PYLQAFVKE
Sbjct: 315  TADIRSELLSVVGKRAVKESDILNLPYLQAFVKE 348


>sp|O64899.1|C80B1_ESCCA RecName: Full=(S)-N-methylcoclaurine 3'-hydroxylase isozyme 1;
            AltName: Full=Cytochrome P450 80B1
            gi|3127027|gb|AAC39452.1| (S)-N-methylcoclaurine
            3'-hydroxylase [Eschscholzia californica]
          Length = 487

 Score =  479 bits (1233), Expect = e-133
 Identities = 241/334 (72%), Positives = 276/334 (82%), Gaps = 1/334 (0%)
 Frame = -1

Query: 1000 SLFYLIFRDSSXXXXXXXXXXXPIVGNLLQLGEKPHSQFAQLAGTYGDLFTLKLGTQTVV 821
            S+ YL+F  S            PIVGNLLQLGEKPH+QFA+LA TYGD+FTLK+GT+TVV
Sbjct: 14   SILYLLFGGSGHKNLPPGPKPWPIVGNLLQLGEKPHAQFAELAQTYGDIFTLKMGTETVV 73

Query: 820  VASTPLAASEILKTHDRVLSGRYVFQSFRIKNHVENCMVWSDCNETWKSLRKVCRTELFT 641
            VAST  AASEILKTHDR+LS RYVFQSFR+K HVEN +VWSDC ETWK+LRKVCRTELFT
Sbjct: 74   VASTSSAASEILKTHDRILSARYVFQSFRVKGHVENSIVWSDCTETWKNLRKVCRTELFT 133

Query: 640  RKMIESQAQVRECKAMELVEYLRKHQGNEVKIVEVIFATLVNIFGNLIFSQNIFKLSDEN 461
            +KMIESQA VRE K  E+VEYL K QG EVKIVEVIF TLVNIFGNLIFSQNIF+L D N
Sbjct: 134  QKMIESQAHVREKKCEEMVEYLMKKQGEEVKIVEVIFGTLVNIFGNLIFSQNIFELGDPN 193

Query: 460  SGSVEMKEQIWRLLELGNSTNPADYFPFLGSLDLLGQRKDVADSLQEIYGVWGPILTEKK 281
            SGS E KE +WR+LELGNSTNPADYFP LG  DL GQRK+VA+ L+ IY +WG +L E+K
Sbjct: 194  SGSSEFKEYLWRMLELGNSTNPADYFPMLGKFDLFGQRKEVAECLKGIYAIWGAMLQERK 253

Query: 280  LAKQ-HNTNTTNDFVDLLLDSGLNDQQINALLMEIFGAGTETSASTIEWALAELIKNPEL 104
            LAK+     + NDFVD+ LDSGLND QINALLME+FGAGTETSASTIEWA+ EL KNP++
Sbjct: 254  LAKKVDGYKSKNDFVDVCLDSGLNDYQINALLMELFGAGTETSASTIEWAMTELTKNPKI 313

Query: 103  TANIRSELLSVVGKRTVKESDIPNMPYLQAFVKE 2
            TA IRSE+ +VVG+R+VKESD PN+PYL+A VKE
Sbjct: 314  TAKIRSEIQTVVGERSVKESDFPNLPYLEATVKE 347


>sp|O64900.1|C80B2_ESCCA RecName: Full=(S)-N-methylcoclaurine 3'-hydroxylase isozyme 2;
            AltName: Full=Cytochrome P450 80B2
            gi|3127029|gb|AAC39453.1| (S)-N-methylcoclaurine
            3'-hydroxylase [Eschscholzia californica]
          Length = 488

 Score =  477 bits (1227), Expect = e-132
 Identities = 240/334 (71%), Positives = 275/334 (82%), Gaps = 1/334 (0%)
 Frame = -1

Query: 1000 SLFYLIFRDSSXXXXXXXXXXXPIVGNLLQLGEKPHSQFAQLAGTYGDLFTLKLGTQTVV 821
            S+ YL+F  S            PIVGNLLQLGEKPH+QFA+LA TYGD+FTLK+GT+TVV
Sbjct: 15   SILYLLFGSSGHKNLPPGPKPWPIVGNLLQLGEKPHAQFAELAQTYGDIFTLKMGTETVV 74

Query: 820  VASTPLAASEILKTHDRVLSGRYVFQSFRIKNHVENCMVWSDCNETWKSLRKVCRTELFT 641
            VAST  AASEILKTHDR+LS RYVFQSFR+K HVEN +VWSDC ETWK+LRKVCRTELFT
Sbjct: 75   VASTSSAASEILKTHDRILSARYVFQSFRVKGHVENSIVWSDCTETWKNLRKVCRTELFT 134

Query: 640  RKMIESQAQVRECKAMELVEYLRKHQGNEVKIVEVIFATLVNIFGNLIFSQNIFKLSDEN 461
            +KMIESQA VRE K  E+VEYL K QG EVKIVEVIF TLVNIFGNLIFSQNIF+L   N
Sbjct: 135  QKMIESQAHVREKKCEEMVEYLMKKQGEEVKIVEVIFGTLVNIFGNLIFSQNIFELGXPN 194

Query: 460  SGSVEMKEQIWRLLELGNSTNPADYFPFLGSLDLLGQRKDVADSLQEIYGVWGPILTEKK 281
            SGS E KE +WR+LELGNSTNPADYFP LG  DL GQRK+VA+ L+ IY +WG +L E+K
Sbjct: 195  SGSSEFKEYLWRMLELGNSTNPADYFPMLGKFDLFGQRKEVAECLKGIYAIWGAMLQERK 254

Query: 280  LAKQ-HNTNTTNDFVDLLLDSGLNDQQINALLMEIFGAGTETSASTIEWALAELIKNPEL 104
            LAK+     + NDFVD+ LDSGLND QINALLME+FGAGTETSASTIEWA+ EL KNP++
Sbjct: 255  LAKKVDGYQSKNDFVDVCLDSGLNDYQINALLMELFGAGTETSASTIEWAMTELTKNPKI 314

Query: 103  TANIRSELLSVVGKRTVKESDIPNMPYLQAFVKE 2
            TA +RSEL +VVG+R+VKESD PN+PYL+A VKE
Sbjct: 315  TAKLRSELQTVVGERSVKESDFPNLPYLEATVKE 348


>sp|Q9FXW4.1|C80B2_COPJA RecName: Full=Probable (S)-N-methylcoclaurine 3'-hydroxylase isozyme
            2; AltName: Full=Cytochrome P450 80B2
            gi|9971208|dbj|BAB12433.1|
            (S)-N-methylcoclaurine-3'-hydroxylase [Coptis japonica]
          Length = 488

 Score =  442 bits (1137), Expect = e-121
 Identities = 216/330 (65%), Positives = 271/330 (82%)
 Frame = -1

Query: 991  YLIFRDSSXXXXXXXXXXXPIVGNLLQLGEKPHSQFAQLAGTYGDLFTLKLGTQTVVVAS 812
            + I RDS            PIVGNLLQLG+KPH++FA+LA  YG+LF+LKLG+QTVVVAS
Sbjct: 18   FFILRDSRPKNLPPGPRPSPIVGNLLQLGDKPHAEFAKLAQKYGELFSLKLGSQTVVVAS 77

Query: 811  TPLAASEILKTHDRVLSGRYVFQSFRIKNHVENCMVWSDCNETWKSLRKVCRTELFTRKM 632
            +P AA+EILKTHD++LSGRYVFQSFR+K HVEN +VWS+CN+ WK LRKVCRTELFT KM
Sbjct: 78   SPAAAAEILKTHDKILSGRYVFQSFRVKEHVENSIVWSECNDNWKLLRKVCRTELFTPKM 137

Query: 631  IESQAQVRECKAMELVEYLRKHQGNEVKIVEVIFATLVNIFGNLIFSQNIFKLSDENSGS 452
            IESQ+++RE KA E+V++LR  +G  VKIVEV+F TLVNIFGNLIFS+++F L D   GS
Sbjct: 138  IESQSEIREAKAREMVKFLRGKEGEVVKIVEVVFGTLVNIFGNLIFSKDVFDLEDPTGGS 197

Query: 451  VEMKEQIWRLLELGNSTNPADYFPFLGSLDLLGQRKDVADSLQEIYGVWGPILTEKKLAK 272
            VE+KE +W+LL++GNSTNPADYFP +G LDL GQR+ VA+ LQ+IY VWG +L E++  K
Sbjct: 198  VELKEHLWKLLDMGNSTNPADYFPIMGKLDLFGQRRAVAEVLQQIYDVWGVMLKERRGTK 257

Query: 271  QHNTNTTNDFVDLLLDSGLNDQQINALLMEIFGAGTETSASTIEWALAELIKNPELTANI 92
               + + NDFVD+LL++GL+DQ+INALLME+FGAGTETSASTIEWA+ EL K P + + I
Sbjct: 258  --GSESKNDFVDVLLNAGLDDQKINALLMELFGAGTETSASTIEWAITELTKKPLVVSKI 315

Query: 91   RSELLSVVGKRTVKESDIPNMPYLQAFVKE 2
            R EL++VVG  TVKESD+P++PYLQAFVKE
Sbjct: 316  RLELVNVVGDNTVKESDLPHLPYLQAFVKE 345


>gb|ABS19627.1| (S)-N-methylcoclaurine-3'-hydroxylase [Coptis chinensis]
          Length = 488

 Score =  433 bits (1114), Expect = e-119
 Identities = 214/330 (64%), Positives = 264/330 (80%)
 Frame = -1

Query: 991  YLIFRDSSXXXXXXXXXXXPIVGNLLQLGEKPHSQFAQLAGTYGDLFTLKLGTQTVVVAS 812
            + I RD             PIVGNLLQLG+KP ++FA+LA  YG LF+LKLG+QTVVVAS
Sbjct: 18   FFILRDPRQKNLPPGPRPLPIVGNLLQLGDKPRAEFAKLAQKYGQLFSLKLGSQTVVVAS 77

Query: 811  TPLAASEILKTHDRVLSGRYVFQSFRIKNHVENCMVWSDCNETWKSLRKVCRTELFTRKM 632
            +P AA+E+LKTHD++LSGRYVFQSFR+K HVEN +VWS+CN+ WK LRKVCRTELFT KM
Sbjct: 78   SPAAAAEVLKTHDKILSGRYVFQSFRVKEHVENSIVWSECNDNWKLLRKVCRTELFTPKM 137

Query: 631  IESQAQVRECKAMELVEYLRKHQGNEVKIVEVIFATLVNIFGNLIFSQNIFKLSDENSGS 452
            IESQ+++RE KA E+V++LR  +G  VKIVEV+F TLVNIFGNLIFS+++F L D   GS
Sbjct: 138  IESQSEIREGKAREMVKFLRSKEGEVVKIVEVVFGTLVNIFGNLIFSKDVFDLEDPTGGS 197

Query: 451  VEMKEQIWRLLELGNSTNPADYFPFLGSLDLLGQRKDVADSLQEIYGVWGPILTEKKLAK 272
            VE+KE +W+LLE+GNSTNPADYFP +G  DL GQR+ VAD LQ+IY VWG  L E++  K
Sbjct: 198  VELKEHLWKLLEMGNSTNPADYFPIMGKYDLFGQRRAVADVLQQIYDVWGINLKERRGMK 257

Query: 271  QHNTNTTNDFVDLLLDSGLNDQQINALLMEIFGAGTETSASTIEWALAELIKNPELTANI 92
               +N  NDFVD+LL++GL DQ+INALLME+FG GTETSASTIEWA+ EL K P + + I
Sbjct: 258  GSESN--NDFVDVLLNAGLEDQKINALLMELFGTGTETSASTIEWAITELTKKPLVVSKI 315

Query: 91   RSELLSVVGKRTVKESDIPNMPYLQAFVKE 2
            R EL++VVG  TVKESD+P++PYLQAFVKE
Sbjct: 316  RLELVNVVGDNTVKESDLPHLPYLQAFVKE 345


>gb|AAU20767.1| (S)-N-methylcoclaurine 3'-hydroxylase [Thalictrum flavum subsp.
           glaucum]
          Length = 491

 Score =  420 bits (1080), Expect = e-115
 Identities = 206/330 (62%), Positives = 262/330 (79%)
 Frame = -1

Query: 991 YLIFRDSSXXXXXXXXXXXPIVGNLLQLGEKPHSQFAQLAGTYGDLFTLKLGTQTVVVAS 812
           + I  DS            PIVGNLLQLGEKPH++FA+LA  YG+LFTLKLG+QTVVVAS
Sbjct: 19  FFILCDSRNKDLPPGPRPSPIVGNLLQLGEKPHAEFAKLAEKYGELFTLKLGSQTVVVAS 78

Query: 811 TPLAASEILKTHDRVLSGRYVFQSFRIKNHVENCMVWSDCNETWKSLRKVCRTELFTRKM 632
           +P AA+EILKT D++LSGRYVFQSFR+  HV N +VWS+CNE WK LRKVCRTELF+ KM
Sbjct: 79  SPAAAAEILKTRDKILSGRYVFQSFRVYEHVLNSIVWSECNENWKLLRKVCRTELFSPKM 138

Query: 631 IESQAQVRECKAMELVEYLRKHQGNEVKIVEVIFATLVNIFGNLIFSQNIFKLSDENSGS 452
           IESQA +RE KA+++V +LRK +  EVKIVEV+F TLVNIFGNLIFS+++F L D   GS
Sbjct: 139 IESQAYIREAKALDMVRFLRKKENQEVKIVEVVFNTLVNIFGNLIFSKDVFDLEDPTGGS 198

Query: 451 VEMKEQIWRLLELGNSTNPADYFPFLGSLDLLGQRKDVADSLQEIYGVWGPILTEKKLAK 272
            E+KE +W+LL++GNSTNPADYFP +G  DL GQR++VA  L++IY VWG +L E++   
Sbjct: 199 AELKEHLWKLLDMGNSTNPADYFPIMGKFDLFGQRREVAKVLKQIYDVWGVMLKERRSIT 258

Query: 271 QHNTNTTNDFVDLLLDSGLNDQQINALLMEIFGAGTETSASTIEWALAELIKNPELTANI 92
            H     NDF ++LL++GL+DQ+INALLME+FGAGTET+ASTIEWA+ EL  N  + + +
Sbjct: 259 GHR---ENDFANVLLNAGLDDQKINALLMELFGAGTETTASTIEWAITELTNNLRVISKL 315

Query: 91  RSELLSVVGKRTVKESDIPNMPYLQAFVKE 2
           R+EL++VVG +TVKES+IP++PYLQA VKE
Sbjct: 316 RAELINVVGHKTVKESNIPHLPYLQAIVKE 345


>emb|CBI31830.3| unnamed protein product [Vitis vinifera]
          Length = 1538

 Score =  277 bits (708), Expect = 6e-72
 Identities = 139/313 (44%), Positives = 203/313 (64%), Gaps = 3/313 (0%)
 Frame = -1

Query: 931  IVGNLLQLGEKPHSQFAQLAGTYGDLFTLKLGTQTVVVASTPLAASEILKTHDRVLSGRY 752
            I+GNLLQ+G+ PH++ A LA  +G L +L+LGTQ +VVAS+P AA E+LKTHDR LSGRY
Sbjct: 587  IIGNLLQMGKNPHAKLANLAKLHGPLMSLRLGTQLMVVASSPAAAMEVLKTHDRALSGRY 646

Query: 751  VFQSFRIKNHVEN---CMVWSDCNETWKSLRKVCRTELFTRKMIESQAQVRECKAMELVE 581
            +  S  +KN   N    +   DCN  WK+LR +CR ELF+ K +ESQ ++RE K  ELVE
Sbjct: 647  LSSSVPVKNPKLNHLSIVFAKDCNTNWKNLRAICRMELFSGKAMESQVELRERKVTELVE 706

Query: 580  YLRKHQGNEVKIVEVIFATLVNIFGNLIFSQNIFKLSDENSGSVEMKEQIWRLLELGNST 401
            +L   +G  VK+++++F T+ NI  N  FS ++    DE      +K+ I +  E G + 
Sbjct: 707  FLATKEGEVVKVMDLVFTTICNILSNKFFSMDLCDFEDEGRVGGALKDLIHKNAEFGATP 766

Query: 400  NPADYFPFLGSLDLLGQRKDVADSLQEIYGVWGPILTEKKLAKQHNTNTTNDFVDLLLDS 221
            N +DY+P LG LD+ G  +   +  + I   W  IL E++  ++ N ++  DF++ LL+ 
Sbjct: 767  NLSDYYPILGGLDIQGINRKAKEMFERIPTTWEDILKERR-TQRSNRSSHRDFLEALLEI 825

Query: 220  GLNDQQINALLMEIFGAGTETSASTIEWALAELIKNPELTANIRSELLSVVGKRTVKESD 41
            G  D QIN +++E+F AG ETS+ T+EWA+AELI+N +    +R EL  +VG+  V+ES 
Sbjct: 826  GFEDDQINQVILELFSAGAETSSLTVEWAMAELIRNQDAMDKLRGELRQIVGESPVRESH 885

Query: 40   IPNMPYLQAFVKE 2
            +P +PYLQA VKE
Sbjct: 886  LPRLPYLQACVKE 898



 Score =  264 bits (674), Expect = 5e-68
 Identities = 136/315 (43%), Positives = 202/315 (64%), Gaps = 5/315 (1%)
 Frame = -1

Query: 931  IVGNLLQLGEKPHSQFAQLAGTYGDLFTLKLGTQTVVVASTPLAASEILKTHDRVLSGRY 752
            I+GNLLQLG+ PH + A LA  +G L +L+LGTQ +VVAS+P AA E+LKTHDR LSGRY
Sbjct: 1092 IIGNLLQLGKNPHVKLASLAKLHGPLMSLRLGTQLMVVASSPAAALEVLKTHDRTLSGRY 1151

Query: 751  VFQSFRIK----NHVENCMVWSDCNETWKSLRKVCRTELFTRKMIESQAQVRECKAMELV 584
            V  S  +K    NH+       +C   WK+LR +CRTE+F+ K +ES  ++RE K MELV
Sbjct: 1152 VSSSLSVKDPKLNHLSLAFA-KECTNNWKNLRTICRTEMFSGKAMESHVELRERKVMELV 1210

Query: 583  EYLRKHQGNEVKIVEVIFATLVNIFGNLIFSQNIFKLSDENSGSVEMKEQIWRLLELGNS 404
            E+L   +G  VK+++++F T+ NI  N  FS ++     E      +K+ I+R  ELG +
Sbjct: 1211 EFLATKEGEVVKVMDLVFTTICNILSNTFFSMDLCDFEREG-----LKDFIYRAAELGAT 1265

Query: 403  TNPADYFPFLGSLDLLGQRKDVADSLQEIYGVWGPILTEKKLAKQHNTNTTN-DFVDLLL 227
             N +D++P L  L+L G +K   ++L  I   W   L E++  KQ N  +++ D ++  L
Sbjct: 1266 PNLSDFYPILDGLNLHGSKKKSKEALGRILATWEGTLKERR--KQKNPGSSHRDLLEAFL 1323

Query: 226  DSGLNDQQINALLMEIFGAGTETSASTIEWALAELIKNPELTANIRSELLSVVGKRTVKE 47
            +    D QIN +++E+F AG +TS  TIEWA+ +LI+NP++   +R EL  ++G+  V+E
Sbjct: 1324 EIRFEDDQINQVILELFSAGADTSTLTIEWAITQLIRNPDVMYKLRDELTKIIGESPVRE 1383

Query: 46   SDIPNMPYLQAFVKE 2
            S +P++PYLQA VKE
Sbjct: 1384 SHLPHLPYLQACVKE 1398



 Score =  255 bits (651), Expect = 3e-65
 Identities = 134/313 (42%), Positives = 202/313 (64%), Gaps = 3/313 (0%)
 Frame = -1

Query: 931 IVGNLLQLGEKPHSQFAQLAGTYGDLFTLKLGTQTVVVASTPLAASEILKTHDRVLSGRY 752
           I+GNLLQ+G   H + A LA  +G L +L+LGTQ +VVAS+  AA E+LKTHDR LSGRY
Sbjct: 47  IIGNLLQMGGNLHVKLANLAKRHGPLMSLRLGTQIMVVASSSAAAMEVLKTHDRTLSGRY 106

Query: 751 VFQSFRIKNHVENCMVWSD---CNETWKSLRKVCRTELFTRKMIESQAQVRECKAMELVE 581
           V  +  + +   N +  +    CN  W++L+ +CR ELF+ K +ES+ ++RE K MELVE
Sbjct: 107 VSTTIPVNSPKLNHLAMAFAKVCNSDWRNLKAICRMELFSGKAMESRVELRERKVMELVE 166

Query: 580 YLRKHQGNEVKIVEVIFATLVNIFGNLIFSQNIFKLSDENSGSVEMKEQIWRLLELGNST 401
           +L K +G  VK++++++ T+ NI  N  FS +       +   V +K+ +    ELG +T
Sbjct: 167 FLEKKEGEVVKVMDLVYTTVCNILSNKFFSIDFSDFEGRDVRGVLLKDLLNENAELG-AT 225

Query: 400 NPADYFPFLGSLDLLGQRKDVADSLQEIYGVWGPILTEKKLAKQHNTNTTNDFVDLLLDS 221
           N  D++P LG LD+ G RK + +  + I   W  IL E++  + H ++   DF+D LL++
Sbjct: 226 NILDFYPILGGLDIQGIRKKLKEIFRRIPTTWEDILKERRKQRIHGSSH-GDFLDALLET 284

Query: 220 GLNDQQINALLMEIFGAGTETSASTIEWALAELIKNPELTANIRSELLSVVGKRTVKESD 41
           G  D QIN ++ME+F AG ETS+ T+EWA+AELIKN +    + +EL  ++G+  V+ES 
Sbjct: 285 GFEDDQINHVIMELFFAGPETSSLTVEWAMAELIKNQDAMHKLCNELTQIIGESPVRESH 344

Query: 40  IPNMPYLQAFVKE 2
           +P++PYLQA VKE
Sbjct: 345 LPHLPYLQACVKE 357


>ref|XP_002274562.1| PREDICTED: probable (S)-N-methylcoclaurine 3'-hydroxylase isozyme 2
           [Vitis vinifera]
          Length = 498

 Score =  277 bits (708), Expect = 6e-72
 Identities = 139/313 (44%), Positives = 203/313 (64%), Gaps = 3/313 (0%)
 Frame = -1

Query: 931 IVGNLLQLGEKPHSQFAQLAGTYGDLFTLKLGTQTVVVASTPLAASEILKTHDRVLSGRY 752
           I+GNLLQ+G+ PH++ A LA  +G L +L+LGTQ +VVAS+P AA E+LKTHDR LSGRY
Sbjct: 47  IIGNLLQMGKNPHAKLANLAKLHGPLMSLRLGTQLMVVASSPAAAMEVLKTHDRALSGRY 106

Query: 751 VFQSFRIKNHVEN---CMVWSDCNETWKSLRKVCRTELFTRKMIESQAQVRECKAMELVE 581
           +  S  +KN   N    +   DCN  WK+LR +CR ELF+ K +ESQ ++RE K  ELVE
Sbjct: 107 LSSSVPVKNPKLNHLSIVFAKDCNTNWKNLRAICRMELFSGKAMESQVELRERKVTELVE 166

Query: 580 YLRKHQGNEVKIVEVIFATLVNIFGNLIFSQNIFKLSDENSGSVEMKEQIWRLLELGNST 401
           +L   +G  VK+++++F T+ NI  N  FS ++    DE      +K+ I +  E G + 
Sbjct: 167 FLATKEGEVVKVMDLVFTTICNILSNKFFSMDLCDFEDEGRVGGALKDLIHKNAEFGATP 226

Query: 400 NPADYFPFLGSLDLLGQRKDVADSLQEIYGVWGPILTEKKLAKQHNTNTTNDFVDLLLDS 221
           N +DY+P LG LD+ G  +   +  + I   W  IL E++  ++ N ++  DF++ LL+ 
Sbjct: 227 NLSDYYPILGGLDIQGINRKAKEMFERIPTTWEDILKERR-TQRSNRSSHRDFLEALLEI 285

Query: 220 GLNDQQINALLMEIFGAGTETSASTIEWALAELIKNPELTANIRSELLSVVGKRTVKESD 41
           G  D QIN +++E+F AG ETS+ T+EWA+AELI+N +    +R EL  +VG+  V+ES 
Sbjct: 286 GFEDDQINQVILELFSAGAETSSLTVEWAMAELIRNQDAMDKLRGELRQIVGESPVRESH 345

Query: 40  IPNMPYLQAFVKE 2
           +P +PYLQA VKE
Sbjct: 346 LPRLPYLQACVKE 358


>emb|CAN62647.1| hypothetical protein VITISV_013219 [Vitis vinifera]
          Length = 498

 Score =  276 bits (707), Expect = 8e-72
 Identities = 139/313 (44%), Positives = 203/313 (64%), Gaps = 3/313 (0%)
 Frame = -1

Query: 931 IVGNLLQLGEKPHSQFAQLAGTYGDLFTLKLGTQTVVVASTPLAASEILKTHDRVLSGRY 752
           I+GNLLQ+G+ PH++ A LA  +G L +L+LGTQ +VVAS+P AA E+LKTHDR LSGRY
Sbjct: 47  IIGNLLQMGKNPHAKLANLAKLHGPLMSLRLGTQLMVVASSPAAAMEVLKTHDRALSGRY 106

Query: 751 VFQSFRIKNHVEN---CMVWSDCNETWKSLRKVCRTELFTRKMIESQAQVRECKAMELVE 581
           +  S  +KN   N    +   DCN  WK+LR +CR ELF+ K +ESQ ++RE K  ELVE
Sbjct: 107 LSXSVPVKNPKLNHLSIVFAKDCNTNWKNLRAICRMELFSGKAMESQVELRERKVTELVE 166

Query: 580 YLRKHQGNEVKIVEVIFATLVNIFGNLIFSQNIFKLSDENSGSVEMKEQIWRLLELGNST 401
           +L   +G  VK+++++F T+ NI  N  FS ++    DE      +K+ I +  E G + 
Sbjct: 167 FLATKEGEVVKVMDLVFTTICNILSNKFFSMDLCDFEDEGRVGGALKDLIHKNAEFGATP 226

Query: 400 NPADYFPFLGSLDLLGQRKDVADSLQEIYGVWGPILTEKKLAKQHNTNTTNDFVDLLLDS 221
           N +DY+P LG LD+ G  +   +  + I   W  IL E++  ++ N ++  DF++ LL+ 
Sbjct: 227 NLSDYYPILGGLDIQGINRKAKEMFERIPTTWEDILKERR-TQRSNRSSHRDFLEALLEI 285

Query: 220 GLNDQQINALLMEIFGAGTETSASTIEWALAELIKNPELTANIRSELLSVVGKRTVKESD 41
           G  D QIN +++E+F AG ETS+ T+EWA+AELI+N +    +R EL  +VG+  V+ES 
Sbjct: 286 GFEDDQINQVILELFSAGAETSSLTVEWAMAELIRNQDAMDKLRGELRQIVGESPVRESH 345

Query: 40  IPNMPYLQAFVKE 2
           +P +PYLQA VKE
Sbjct: 346 LPRLPYLQACVKE 358


>dbj|BAF80448.1| corytuberine synthase [Coptis japonica var. dissecta]
          Length = 486

 Score =  271 bits (692), Expect = 4e-70
 Identities = 142/315 (45%), Positives = 207/315 (65%), Gaps = 5/315 (1%)
 Frame = -1

Query: 931 IVGNLLQL---GEKP-HSQFAQLAGTYGDLFTLKLGTQTVVVASTPLAASEILKTHDRVL 764
           ++GNL  L    E P H   A +A T+G +  L LGTQ  V+AST  AA EILKTHDR+ 
Sbjct: 37  LIGNLPILFTNTEVPLHITLANMARTHGPIMILWLGTQPTVMASTAEAAMEILKTHDRIF 96

Query: 763 SGRYVFQSFRIKNHVENCMVWSDCNETWKSLRKVCRTELFTRKMIESQAQVRECKAMELV 584
           S R++  SFR+K+H++  +VWSDC + WK LRK+ RTE+F+ KM+++Q+ VRE K  EL+
Sbjct: 97  SARHIRMSFRLKHHIKYSLVWSDCTDYWKLLRKIVRTEIFSPKMLQAQSHVREQKVAELI 156

Query: 583 EYLRKHQGNEVKIVEVIFATLVNIFGNLIFSQNIFKLSDE-NSGSVEMKEQIWRLLELGN 407
           ++LR  +G  VKI + +F TL+NI GN++FS+++F   DE + G ++    I  +L +G 
Sbjct: 157 DFLRSKEGQVVKISQFVFGTLLNILGNVVFSKDVFVYGDETDKGGIQ--NLIREMLMIGA 214

Query: 406 STNPADYFPFLGSLDLLGQRKDVADSLQEIYGVWGPILTEKKLAKQHNTNTTNDFVDLLL 227
             N A+++P L  LDL G +K   +    +  +W   + E+   K +    + D +D+LL
Sbjct: 215 EPNVAEFYPSLEELDLQGLKKKCDERFIRVMKMWEGTVKER---KANRNEESKDMLDVLL 271

Query: 226 DSGLNDQQINALLMEIFGAGTETSASTIEWALAELIKNPELTANIRSELLSVVGKRTVKE 47
            +  ND QINAL +E FG G+ETS++TIEW +AELIK+P+  A +R EL  VVG  T+KE
Sbjct: 272 ANDFNDAQINALFLETFGPGSETSSATIEWVIAELIKSPKEMAKVRKELNEVVGTSTIKE 331

Query: 46  SDIPNMPYLQAFVKE 2
           SD+P +PYLQA +KE
Sbjct: 332 SDLPQLPYLQACIKE 346


>ref|XP_002274530.1| PREDICTED: (S)-N-methylcoclaurine 3'-hydroxylase isozyme 2-like
           [Vitis vinifera]
          Length = 515

 Score =  264 bits (674), Expect = 5e-68
 Identities = 136/315 (43%), Positives = 202/315 (64%), Gaps = 5/315 (1%)
 Frame = -1

Query: 931 IVGNLLQLGEKPHSQFAQLAGTYGDLFTLKLGTQTVVVASTPLAASEILKTHDRVLSGRY 752
           I+GNLLQLG+ PH + A LA  +G L +L+LGTQ +VVAS+P AA E+LKTHDR LSGRY
Sbjct: 47  IIGNLLQLGKNPHVKLASLAKLHGPLMSLRLGTQLMVVASSPAAALEVLKTHDRTLSGRY 106

Query: 751 VFQSFRIK----NHVENCMVWSDCNETWKSLRKVCRTELFTRKMIESQAQVRECKAMELV 584
           V  S  +K    NH+       +C   WK+LR +CRTE+F+ K +ES  ++RE K MELV
Sbjct: 107 VSSSLSVKDPKLNHLSLAFA-KECTNNWKNLRTICRTEMFSGKAMESHVELRERKVMELV 165

Query: 583 EYLRKHQGNEVKIVEVIFATLVNIFGNLIFSQNIFKLSDENSGSVEMKEQIWRLLELGNS 404
           E+L   +G  VK+++++F T+ NI  N  FS ++     E      +K+ I+R  ELG +
Sbjct: 166 EFLATKEGEVVKVMDLVFTTICNILSNTFFSMDLCDFEREG-----LKDFIYRAAELGAT 220

Query: 403 TNPADYFPFLGSLDLLGQRKDVADSLQEIYGVWGPILTEKKLAKQHNTNTTN-DFVDLLL 227
            N +D++P L  L+L G +K   ++L  I   W   L E++  KQ N  +++ D ++  L
Sbjct: 221 PNLSDFYPILDGLNLHGSKKKSKEALGRILATWEGTLKERR--KQKNPGSSHRDLLEAFL 278

Query: 226 DSGLNDQQINALLMEIFGAGTETSASTIEWALAELIKNPELTANIRSELLSVVGKRTVKE 47
           +    D QIN +++E+F AG +TS  TIEWA+ +LI+NP++   +R EL  ++G+  V+E
Sbjct: 279 EIRFEDDQINQVILELFSAGADTSTLTIEWAITQLIRNPDVMYKLRDELTKIIGESPVRE 338

Query: 46  SDIPNMPYLQAFVKE 2
           S +P++PYLQA VKE
Sbjct: 339 SHLPHLPYLQACVKE 353


>ref|XP_006358914.1| PREDICTED: probable (S)-N-methylcoclaurine 3'-hydroxylase isozyme
           2-like [Solanum tuberosum]
          Length = 496

 Score =  260 bits (664), Expect = 8e-67
 Identities = 132/314 (42%), Positives = 207/314 (65%), Gaps = 4/314 (1%)
 Frame = -1

Query: 931 IVGNLLQLGEKPHSQFAQLAGTYGDLFTLKLGTQTVVVASTPLAASEILKTHDRVLSGRY 752
           ++GN+ Q+G+ PH      A TYG L +L+LGTQ +VV S+P  A EI KTHDR+LSGR+
Sbjct: 44  VIGNIFQIGKMPHITLTNFAKTYGPLISLRLGTQCLVVGSSPSVAIEIFKTHDRILSGRH 103

Query: 751 VFQSFRIKNH--VENCMVW-SDCNETWKSLRKVCRTELFTRKMIESQAQVRECKAMELVE 581
           V  + R K     +  + W S+C+  W+ LR +CRT+LF  K++ESQA +RE K MELVE
Sbjct: 104 VPNAVRSKGSDLEKTSLGWKSECDSGWRYLRTLCRTDLFAGKVLESQACLREKKVMELVE 163

Query: 580 YLRKHQGNEVKIVEVIFATLVNIFGNLIFSQNIFKLSDENSGSVEMKEQIWRLLELGNST 401
           +LR  +G  V I E++FAT++N+  N++ S+++  L +E   S E+K  +  ++E+G++ 
Sbjct: 164 FLRSKEGQVVNIGELVFATVLNMLSNVLISKDMIHLEEETEDS-EIKSLVRGIVEVGSAP 222

Query: 400 NPADYFPFLGSLDLLGQRKDVADSLQEIYGVWGPILTEKKLAKQHNTNTTNDFVDLLLDS 221
           N +D++P LG LDL G RK   D + +   +W PI+ E++ ++++++++  DF++ LLD+
Sbjct: 223 NISDFYPILGKLDLQGLRKKSTDLVTKFCSIWEPIIEERRNSRENDSSSQQDFLETLLDN 282

Query: 220 GLNDQQINALLMEIFGAGTETSASTIEWALAELIKNPELTANIRSEL-LSVVGKRTVKES 44
           G  +  IN L ME+  AG++TS + IEWA+AELIKN E    ++ EL + +     +KES
Sbjct: 283 GFTNDHINQLFMELLSAGSDTSTTAIEWAMAELIKNVETMKKVQEELEIELSESDYLKES 342

Query: 43  DIPNMPYLQAFVKE 2
            +  M Y+QA VKE
Sbjct: 343 QVLQMSYVQACVKE 356


>ref|XP_002510830.1| (S)-N-methylcoclaurine 3'-hydroxylase isozyme, putative [Ricinus
           communis] gi|223549945|gb|EEF51432.1|
           (S)-N-methylcoclaurine 3'-hydroxylase isozyme, putative
           [Ricinus communis]
          Length = 496

 Score =  258 bits (659), Expect = 3e-66
 Identities = 129/314 (41%), Positives = 202/314 (64%), Gaps = 4/314 (1%)
 Frame = -1

Query: 931 IVGNLLQLGEKPHSQFAQLAGTYGDLFTLKLGTQTVVVASTPLAASEILKTHDRVLSGRY 752
           I+GN+LQ+ +K H   A  A  YG L +L+LG Q +VVASTP +A+E+LK HDR+LS R+
Sbjct: 45  ILGNILQVDKKLHICIANFAKVYGPLISLRLGNQVLVVASTPSSAAEVLKNHDRLLSARF 104

Query: 751 VFQSFRIKNHVEN--CMVWSD-CNETWKSLRKVCRTELFTRKMIESQAQVRECKAMELVE 581
           + ++   ++H+     +VW+  CN+ WKSLR +CRTELF+ K IESQA +RE K  E++E
Sbjct: 105 ILKAIPSESHILERVAIVWNPACNDHWKSLRALCRTELFSPKAIESQAILREKKLAEMLE 164

Query: 580 YLRKHQGNEVKIVEVIFATLVNIFGNLIFSQNIFKLSDENSGSVEMKEQIWRLLELGNST 401
           +L   QG  V + EV+F T+ N   +L+FS ++    ++  G   +K  +W ++E+  S 
Sbjct: 165 FLITKQGQAVNVAEVVFGTIFNTISHLLFSTDLIGFENQIGG---VKSLLWSMMEMATSP 221

Query: 400 NPADYFPFLGSLDLLGQRKDVADSLQEIYGVWGPILTEKKLAKQHN-TNTTNDFVDLLLD 224
           N A+++P L  LD  G ++ +   L+E++GVW   + E++    H+      DF+D+ L 
Sbjct: 222 NIAEFYPILAPLDPQGLKRKMTKCLKEMFGVWEIYIKERRRTHDHDHAAPKTDFLDIFLS 281

Query: 223 SGLNDQQINALLMEIFGAGTETSASTIEWALAELIKNPELTANIRSELLSVVGKRTVKES 44
           +G +D QIN L+ME+  AGT+T+++++EWA+AEL+KN E    +R EL   + K  +KES
Sbjct: 282 NGFDDDQINWLVMELLSAGTDTTSTSVEWAMAELLKNKEAMKKVREELDREINKNPIKES 341

Query: 43  DIPNMPYLQAFVKE 2
            +  +PYL A VKE
Sbjct: 342 HVSQLPYLNACVKE 355


>ref|XP_002513347.1| (S)-N-methylcoclaurine 3'-hydroxylase isozyme, putative [Ricinus
           communis] gi|223547255|gb|EEF48750.1|
           (S)-N-methylcoclaurine 3'-hydroxylase isozyme, putative
           [Ricinus communis]
          Length = 496

 Score =  257 bits (656), Expect = 7e-66
 Identities = 134/313 (42%), Positives = 204/313 (65%), Gaps = 3/313 (0%)
 Frame = -1

Query: 931 IVGNLLQLGEKPHSQFAQLAGTYGDLFTLKLGTQTVVVASTPLAASEILKTHDRVLSGRY 752
           I+GN+LQ+G+ PH   A  A  +G L +L+LGT+ VVVAS+P AA+EILKTHDR+LSGRY
Sbjct: 46  ILGNILQVGKNPHISMANYAKVHGPLISLRLGTRVVVVASSPTAAAEILKTHDRLLSGRY 105

Query: 751 VFQSFRIKNHVEN--CMVWS-DCNETWKSLRKVCRTELFTRKMIESQAQVRECKAMELVE 581
           +  +   +++V +   +VW+  C++ WK LR +CR+ELF+ K IESQA +RE K  E+++
Sbjct: 106 IPATTPYEDNVLDRIALVWNPSCSDQWKFLRAMCRSELFSAKAIESQATLREKKLTEMLD 165

Query: 580 YLRKHQGNEVKIVEVIFATLVNIFGNLIFSQNIFKLSDENSGSVEMKEQIWRLLELGNST 401
           +L   QG  V I EV+F T  N   NL+FS+++    D+ +   E+K  I  L+EL    
Sbjct: 166 FLTSKQGQIVNIGEVVFTTAFNTISNLLFSKDLLSFEDQGNAG-ELKTLISTLMELATCP 224

Query: 400 NPADYFPFLGSLDLLGQRKDVADSLQEIYGVWGPILTEKKLAKQHNTNTTNDFVDLLLDS 221
           N AD++P L  LD  G ++ + + L+ ++GVW   + E++     +   T DF+D+ L +
Sbjct: 225 NIADFYPVLTKLDPQGIKRKMKNCLERMFGVWDIYIKERRERHVKDARKT-DFLDVFLSN 283

Query: 220 GLNDQQINALLMEIFGAGTETSASTIEWALAELIKNPELTANIRSELLSVVGKRTVKESD 41
           G +D QIN LL+E+F AG +T+ +T+EWA+AEL+K   +   +R EL + +GK  ++ES 
Sbjct: 284 GFDDHQINWLLLELFSAGADTTTTTVEWAMAELLKEITVLEKVREELETEIGKDMIRESH 343

Query: 40  IPNMPYLQAFVKE 2
           IP + YL A VKE
Sbjct: 344 IPQLKYLNACVKE 356


>ref|XP_002274586.2| PREDICTED: (S)-N-methylcoclaurine 3'-hydroxylase isozyme 2-like
           [Vitis vinifera]
          Length = 498

 Score =  255 bits (651), Expect = 3e-65
 Identities = 134/313 (42%), Positives = 202/313 (64%), Gaps = 3/313 (0%)
 Frame = -1

Query: 931 IVGNLLQLGEKPHSQFAQLAGTYGDLFTLKLGTQTVVVASTPLAASEILKTHDRVLSGRY 752
           I+GNLLQ+G   H + A LA  +G L +L+LGTQ +VVAS+  AA E+LKTHDR LSGRY
Sbjct: 47  IIGNLLQMGGNLHVKLANLAKRHGPLMSLRLGTQIMVVASSSAAAMEVLKTHDRTLSGRY 106

Query: 751 VFQSFRIKNHVENCMVWSD---CNETWKSLRKVCRTELFTRKMIESQAQVRECKAMELVE 581
           V  +  + +   N +  +    CN  W++L+ +CR ELF+ K +ES+ ++RE K MELVE
Sbjct: 107 VSTTIPVNSPKLNHLAMAFAKVCNSDWRNLKAICRMELFSGKAMESRVELRERKVMELVE 166

Query: 580 YLRKHQGNEVKIVEVIFATLVNIFGNLIFSQNIFKLSDENSGSVEMKEQIWRLLELGNST 401
           +L K +G  VK++++++ T+ NI  N  FS +       +   V +K+ +    ELG +T
Sbjct: 167 FLEKKEGEVVKVMDLVYTTVCNILSNKFFSIDFSDFEGRDVRGVLLKDLLNENAELG-AT 225

Query: 400 NPADYFPFLGSLDLLGQRKDVADSLQEIYGVWGPILTEKKLAKQHNTNTTNDFVDLLLDS 221
           N  D++P LG LD+ G RK + +  + I   W  IL E++  + H ++   DF+D LL++
Sbjct: 226 NILDFYPILGGLDIQGIRKKLKEIFRRIPTTWEDILKERRKQRIHGSSH-GDFLDALLET 284

Query: 220 GLNDQQINALLMEIFGAGTETSASTIEWALAELIKNPELTANIRSELLSVVGKRTVKESD 41
           G  D QIN ++ME+F AG ETS+ T+EWA+AELIKN +    + +EL  ++G+  V+ES 
Sbjct: 285 GFEDDQINHVIMELFFAGPETSSLTVEWAMAELIKNQDAMHKLCNELTQIIGESPVRESH 344

Query: 40  IPNMPYLQAFVKE 2
           +P++PYLQA VKE
Sbjct: 345 LPHLPYLQACVKE 357


>emb|CAN70170.1| hypothetical protein VITISV_006874 [Vitis vinifera]
          Length = 559

 Score =  255 bits (651), Expect = 3e-65
 Identities = 134/313 (42%), Positives = 202/313 (64%), Gaps = 3/313 (0%)
 Frame = -1

Query: 931 IVGNLLQLGEKPHSQFAQLAGTYGDLFTLKLGTQTVVVASTPLAASEILKTHDRVLSGRY 752
           I+GNLLQ+G   H + A LA  +G L +L+LGTQ +VVAS+  AA E+LKTHDR LSGRY
Sbjct: 47  IIGNLLQMGGNLHVKLANLAKRHGPLMSLRLGTQIMVVASSSAAAMEVLKTHDRTLSGRY 106

Query: 751 VFQSFRIKNHVENCMVWSD---CNETWKSLRKVCRTELFTRKMIESQAQVRECKAMELVE 581
           V  +  + +   N +  +    CN  W++L+ +CR ELF+ K +ES+ ++RE K MELVE
Sbjct: 107 VSTTIPVNSPKLNHLAMAFAKVCNSDWRNLKAICRMELFSGKAMESRVELRERKVMELVE 166

Query: 580 YLRKHQGNEVKIVEVIFATLVNIFGNLIFSQNIFKLSDENSGSVEMKEQIWRLLELGNST 401
           +L K +G  VK++++++ T+ NI  N  FS +       +   V +K+ +    ELG +T
Sbjct: 167 FLEKKEGEVVKVMDLVYTTVCNILSNKFFSIDFSDFEGRDVRGVLLKDLLNENAELG-AT 225

Query: 400 NPADYFPFLGSLDLLGQRKDVADSLQEIYGVWGPILTEKKLAKQHNTNTTNDFVDLLLDS 221
           N  D++P LG LD+ G RK + +  + I   W  IL E++  + H ++   DF+D LL++
Sbjct: 226 NILDFYPILGGLDIQGIRKKLKEIFRRIPTTWEDILKERRKQRIHGSSH-GDFLDALLET 284

Query: 220 GLNDQQINALLMEIFGAGTETSASTIEWALAELIKNPELTANIRSELLSVVGKRTVKESD 41
           G  D QIN ++ME+F AG ETS+ T+EWA+AELIKN +    + +EL  ++G+  V+ES 
Sbjct: 285 GFEDDQINHVIMELFFAGPETSSLTVEWAMAELIKNQDAMHKLCNELTQIIGESPVRESH 344

Query: 40  IPNMPYLQAFVKE 2
           +P++PYLQA VKE
Sbjct: 345 LPHLPYLQACVKE 357


>ref|XP_006358915.1| PREDICTED: probable (S)-N-methylcoclaurine 3'-hydroxylase isozyme
            2-like [Solanum tuberosum]
          Length = 495

 Score =  252 bits (644), Expect = 2e-64
 Identities = 138/334 (41%), Positives = 212/334 (63%), Gaps = 4/334 (1%)
 Frame = -1

Query: 991  YLIFRDSSXXXXXXXXXXXPIVGNLLQLGEKPHSQFAQLAGTYGDLFTLKLGTQTVVVAS 812
            + IF+ S            P++GN+ Q+G+ PH      A TYG L +LKLGT+ +VV S
Sbjct: 23   FKIFKSSKITQLPPGPTPWPVIGNIFQMGKMPHITLTNFAKTYGPLMSLKLGTKWLVVGS 82

Query: 811  TPLAASEILKTHDRVLSGRYVFQSFRIKNHV--ENCMVW-SDCNETWKSLRKVCRTELFT 641
            +PLAA EILKTHD++LSGR V  +   K     +  + W S+CN  W+ LR +CRTELF 
Sbjct: 83   SPLAAVEILKTHDKILSGRDVPSAAPSKGSDLDKTSLGWISECNSGWRYLRTLCRTELFA 142

Query: 640  RKMIESQAQVRECKAMELVEYLRKHQGNEVKIVEVIFATLVNIFGNLIFSQNIFKLSDEN 461
             K++ESQA +RE K MELVE+LR  +G  V I E++FAT++N+  N++ S+++  L +E 
Sbjct: 143  GKVLESQACLREKKVMELVEFLRSKEGQVVNIGELVFATVLNMLSNVLISKDMVNLEEEI 202

Query: 460  SGSVEMKEQIWRLLELGNSTNPADYFPFLGSLDLLGQRKDVADSLQEIYGVWGPILTEKK 281
               V +K  +  ++E+ ++ N +D +P LG LDL G +K   D + ++   W PIL E++
Sbjct: 203  EDGV-IKSLVRGIVEVLSAPNISDLYPILGKLDLQGLQKKSIDLVTKLCSNWEPILEERR 261

Query: 280  LAKQHNTNTTNDFVDLLLDSGLNDQQINALLMEIFGAGTETSASTIEWALAELIKNPELT 101
             +++  +++  DF++ LLD+G  + +I+ LLME+  AG++TS STIEWA+AEL+KN E  
Sbjct: 262  NSREKGSSSQQDFLETLLDNGFTNDRIHQLLMELLSAGSDTSTSTIEWAMAELMKNVESM 321

Query: 100  ANIRSEL-LSVVGKRTVKESDIPNMPYLQAFVKE 2
              ++ EL + +     +KES +  M Y+QA VKE
Sbjct: 322  KKVQEELEIELSESDYLKESQLLQMSYIQACVKE 355