BLASTX nr result
ID: Paeonia25_contig00014740
seq
BLASTX 2.2.25 [Feb-01-2011]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Paeonia25_contig00014740
(1702 letters)
Database: ./nr
38,876,450 sequences; 13,856,398,315 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gb|EMD31428.1| hypothetical protein CERSUDRAFT_109437 [Ceriporio... 432 e-118
gb|EMD31509.1| hypothetical protein CERSUDRAFT_119728 [Ceriporio... 402 e-109
ref|XP_007387605.1| cytochrome P450 [Punctularia strigosozonata ... 310 1e-81
gb|EJU01201.1| cytochrome P450 [Dacryopinax sp. DJM-731 SS1] 225 4e-56
ref|XP_007361145.1| hypothetical protein DICSQDRAFT_48897 [Dicho... 182 5e-43
gb|EUC63789.1| cytochrome P450 family protein [Rhizoctonia solan... 174 1e-40
gb|ELU37886.1| cytochrome P450 domain-containing protein [Rhizoc... 162 6e-37
ref|XP_007315026.1| hypothetical protein SERLADRAFT_459654 [Serp... 157 1e-35
ref|XP_003759804.1| PREDICTED: cholesterol 7-alpha-monooxygenase... 151 8e-34
ref|XP_002758974.1| PREDICTED: cholesterol 7-alpha-monooxygenase... 150 2e-33
ref|XP_002936154.1| PREDICTED: cholesterol 7-alpha-monooxygenase... 149 3e-33
ref|XP_006113686.1| PREDICTED: cholesterol 7-alpha-monooxygenase... 149 5e-33
ref|XP_006003627.1| PREDICTED: cholesterol 7-alpha-monooxygenase... 149 5e-33
ref|XP_005301221.1| PREDICTED: cholesterol 7-alpha-monooxygenase... 147 2e-32
dbj|BAN16581.1| cytochrome P450 family 7 subfamily a polypeptide... 147 2e-32
ref|XP_002819157.1| PREDICTED: cholesterol 7-alpha-monooxygenase... 147 2e-32
ref|XP_006899296.1| PREDICTED: cholesterol 7-alpha-monooxygenase... 146 3e-32
ref|XP_005362416.1| PREDICTED: 25-hydroxycholesterol 7-alpha-hyd... 146 3e-32
ref|XP_002597173.1| hypothetical protein BRAFLDRAFT_66301 [Branc... 145 4e-32
ref|XP_006003615.1| PREDICTED: cholesterol 7-alpha-monooxygenase... 145 5e-32
>gb|EMD31428.1| hypothetical protein CERSUDRAFT_109437 [Ceriporiopsis subvermispora
B]
Length = 487
Score = 432 bits (1111), Expect = e-118
Identities = 219/482 (45%), Positives = 300/482 (62%), Gaps = 3/482 (0%)
Frame = -2
Query: 1659 WLILAASIAIFAYVVIGRNKNTHRPPQVPYFLPWIGSAISMGKDPDAFVDSCITRYGSVF 1480
W +L S+ + Y + R+ + RPP VPY +PW+GSA+ + KDPD F RYGSVF
Sbjct: 5 WALLLLSVTVLGYFLRFRSTRSRRPPLVPYTIPWLGSALDLNKDPDKFFREASARYGSVF 64
Query: 1479 RVLVLGQQMTFVTDPSLISLVYRDSQHFDFSRIGRQYSLDIFGIPSDI-YDSAIRYSYAE 1303
RV LGQ++T+VT PSLI +YRD++H++F + + +F ++ + A+ +Y
Sbjct: 65 RVKALGQEITYVTAPSLIQGIYRDNKHYEFMPLRLEIMEKVFATAHEVTHAPAMIDTYFP 124
Query: 1302 AQHRALLPQSVRPLLRQYTEQAHKLFLEAIDRADGTSVDLSSFLIPPTYCSAATTMLGKE 1123
AQHRAL P +V LL Y E+A +LF +AID ADGTS+ L F+IPPTYC+AA +LGK+
Sbjct: 125 AQHRALAPSNVPELLSAYAERAFELFSKAIDGADGTSMSLIQFIIPPTYCAAAAALLGKD 184
Query: 1122 FPAEKSMPFFQAFDKDFPLMAAGLPRIVTRQARQAWDKLIDILREYMEAVEHEQD--IPE 949
FPA ++ F+ FD FPLM AGLPR + +AW ++I ++ +Y+E + ++D +P
Sbjct: 185 FPAMETYAPFRKFDDAFPLMLAGLPRFMLPGPHKAWWEVIRLIEQYLETAKQKEDAELPA 244
Query: 948 ILRNPIHYAREGKWPLRVAASLLGVVLWALSANAPWVAYWLIVHAVQEPLGLTPLQEEVD 769
+R+ + A W AA++L LWA ANA W YWLIV +QEP GL PL EE+D
Sbjct: 245 FVRSTLSMADGSGWSTETAATVLASYLWAAEANAIWAGYWLIVFMLQEPGGLAPLVEELD 304
Query: 768 HARKQWLASQPGTRLTSENFHDFIIESTDNFPLVTSVINETLRYTSASASLREVRAPVEL 589
AR WLA+ PGT LT + FH FI +S PL+ S I ETLR TS +LR V PVE+
Sbjct: 305 RARAAWLAAHPGTPLTPDAFHTFIADSAGALPLLGSAIQETLRVTSDVMALRRVIEPVEM 364
Query: 588 GGYHFETGEKVMVSARPVHMDENIHPDPRSFKMDRYVDFQTPQKDGKLVTNHTLPFGGGV 409
GY GE+V+ R VH+DE IHP +F+ RY++ Q K+GK V NH++PFGGGV
Sbjct: 365 EGYELGVGERVVSVTRLVHLDEEIHPGAEAFRPTRYLENQKFTKNGKAVPNHSMPFGGGV 424
Query: 408 SMCTGRHFAXXXXXXXXXXXLTYATIEVDPSSSQRPSFDWGRFGSGMLSAKGDMRVIIKK 229
SMC GRHF LTYATI +DP + P R G+G++ GD+ VIIK+
Sbjct: 425 SMCEGRHFVMGELKILIALLLTYATIGIDPKKPEIPKMSRNRIGAGIMPPIGDLNVIIKR 484
Query: 228 RK 223
R+
Sbjct: 485 RQ 486
>gb|EMD31509.1| hypothetical protein CERSUDRAFT_119728 [Ceriporiopsis subvermispora
B]
Length = 500
Score = 402 bits (1034), Expect = e-109
Identities = 193/480 (40%), Positives = 293/480 (61%), Gaps = 2/480 (0%)
Frame = -2
Query: 1656 LILAASIAIFAYVVIGRNKNTHRPPQVPYFLPWIGSAISMGKDPDAFVDSCITRYGSVFR 1477
L+L + +F YV ++ HRPP+VPY++PW+GSAI MG++PDAF + RYG VF+
Sbjct: 17 LVLFVAGVLFFYVK-QQSSGLHRPPRVPYWIPWLGSAIEMGRNPDAFFEKMTQRYGPVFK 75
Query: 1476 VLVLGQQMTFVTDPSLISLVYRDSQHFDFSRIGRQYSLDIFGIPSDIYDSAIRYSYAEAQ 1297
+ +G+ M +VT P+LI ++RDS+H+DF I + + ++F IP + S+ A
Sbjct: 76 LKTVGKSMIYVTSPTLIQSIFRDSKHYDFHDIRMKMNEEVFLIPGAAMPPDLVKSWFLAH 135
Query: 1296 HRALLPQSVRPLLRQYTEQAHKLFLEAIDRADGTSVDLSSFLIPPTYCSAATTMLGKEFP 1117
HR L P SV +L+ YT AH L +I G ++ F++P Y + + G+ FP
Sbjct: 136 HRVLAPTSVPEMLKHYTHHAHHNVLASIAEMSGRKTRMADFIVPTAYEATGKALFGELFP 195
Query: 1116 AEKSMPFFQAFDKDFPLMAAGLPRIVTRQARQAWDKLIDILREYMEAVEHEQDI--PEIL 943
A +++ FQ FD+DFPLMAAG P + +AR+AW +I +L +Y++ VE ++D+ P +
Sbjct: 196 ARQTLANFQRFDRDFPLMAAGAPGFMLAKARRAWWNVISVLEDYVKEVELDEDVDVPPLA 255
Query: 942 RNPIHYAREGKWPLRVAASLLGVVLWALSANAPWVAYWLIVHAVQEPLGLTPLQEEVDHA 763
+ + ++G W R AA ++ +WA N W AYW++ + EP GL PL E+D A
Sbjct: 256 KLTLDVKQQGGWDARTAAIVMAADMWASQTNGLWAAYWVMAFMLFEPNGLAPLVAEIDRA 315
Query: 762 RKQWLASQPGTRLTSENFHDFIIESTDNFPLVTSVINETLRYTSASASLREVRAPVELGG 583
R W++ P L + FH+F+ +ST PL+ S + E+LR +S+ +R V PVELGG
Sbjct: 316 RTSWVSQHPEKTLDATTFHEFMADSTKAMPLLASAVQESLRISSSVMPIRRVVEPVELGG 375
Query: 582 YHFETGEKVMVSARPVHMDENIHPDPRSFKMDRYVDFQTPQKDGKLVTNHTLPFGGGVSM 403
Y + + V+ R VH+D+ IHPD +F++DRY + +T KDG+ V NH++PFGGGVS+
Sbjct: 376 YSLQKDDVVIAVTRAVHLDDEIHPDAAAFRVDRYCEGKTFTKDGRSVPNHSMPFGGGVSI 435
Query: 402 CTGRHFAXXXXXXXXXXXLTYATIEVDPSSSQRPSFDWGRFGSGMLSAKGDMRVIIKKRK 223
C GRHF LTYAT+E+ S RP FDW R GSG++ +GD+ VI++KR+
Sbjct: 436 CEGRHFVIGELKTLVALILTYATVELADRSGVRPEFDWSRLGSGIMQPRGDIDVIVRKRE 495
>ref|XP_007387605.1| cytochrome P450 [Punctularia strigosozonata HHB-11173 SS5]
gi|390595798|gb|EIN05202.1| cytochrome P450 [Punctularia
strigosozonata HHB-11173 SS5]
Length = 516
Score = 310 bits (794), Expect = 1e-81
Identities = 189/513 (36%), Positives = 268/513 (52%), Gaps = 30/513 (5%)
Frame = -2
Query: 1671 AELTWLILAASIAIFAYVVIGRN--KNTHRPPQVPYFLPWIGSAISMGKDPDAFVDSCIT 1498
A LT +A S+A+ V I R+ K PP VPY +PW+GSA++MGKDPDAF
Sbjct: 9 ASLTGNEIALSLAVVLLVAIARSSAKRNDGPPLVPYLVPWVGSAVTMGKDPDAFFTMAKE 68
Query: 1497 RYGSVFRVLVLGQQMTFVTDPSLISLVYRDSQHFDFSRIGRQYSLDIFGIPSDI-YDSAI 1321
++G++F V +GQ++T+VTDP+LIS VYRD + F+F+ I S IF + + D +
Sbjct: 69 KFGAMFAVKSIGQKLTYVTDPALISAVYRDPKSFEFTPIRLDISQKIFALSHGVCNDGWM 128
Query: 1320 RYSYAEAQHRALLPQSVRPLLRQYTEQAHKLFLEAID---------RADGTSVDLSSFLI 1168
Y HRAL P ++PLL YT A EA+ + L+ ++
Sbjct: 129 TGDYFSMHHRALSPSGIQPLLASYTTHAISCISEALSALPPSTSAGSSPSCKTSLAPLIV 188
Query: 1167 PPTYCSAATTMLGKEFPAEKSMPFFQAFDKDFPLMAAGLPRIVTRQARQAWDKLIDILRE 988
PP + SAA T G FPA+ F+ FD F LM AG P+ + A+ +++D +
Sbjct: 189 PPAFYSAAHTFFGASFPAKDVYGDFRTFDGSFHLMLAGAPKWLVSAPHDAYARILDKVER 248
Query: 987 YMEAVEHEQDIPEILRNPIHYAREGKWPLRVAASLLGVVLWALSANAPWVAYWLIVHAVQ 808
+++ HE D+ +++ + AR W R A+ LWAL ANA W YW+I +Q
Sbjct: 249 FLDG-PHE-DVCQLMHDTEIGARAQGWGKRDIAAAFASDLWALEANAIWAVYWVIALCLQ 306
Query: 807 EPLGLTPLQEEVDHARKQWLASQPGTRLTSE--------NFHDFIIESTDNFPLVTSVIN 652
+ GL PL +E+ AR W A+ P + S+ FI +T + PL+TS I
Sbjct: 307 QSHGLEPLVKELQEARAAWSAANPSSPFPSDLLDPSAAVTITSFI--ATSSLPLLTSSIY 364
Query: 651 ETLRYTSASASLREVRA-------PVELG---GYHFETGEKVMVSARPVHMDENIHPDPR 502
E LRY ++S S+R V P G Y F GE+++ + R VH D+ IH D
Sbjct: 365 EALRYATSSFSIRRVTRDLVFPTNPEAFGLERSYSFTEGERIVCATRAVHQDKGIHDDAE 424
Query: 501 SFKMDRYVDFQTPQKDGKLVTNHTLPFGGGVSMCTGRHFAXXXXXXXXXXXLTYATIEVD 322
FK DRY + +GK+ + LPFGGGVSMC GRHFA L AT EVD
Sbjct: 425 EFKFDRYAGCK--MNEGKMGRSQFLPFGGGVSMCEGRHFALGEIKTYLTILLLSATFEVD 482
Query: 321 PSSSQRPSFDWGRFGSGMLSAKGDMRVIIKKRK 223
SS RP R G G++ KGD+ VI+++R+
Sbjct: 483 SGSSARPVLLKERIGVGIMPPKGDLDVIVRRRE 515
>gb|EJU01201.1| cytochrome P450 [Dacryopinax sp. DJM-731 SS1]
Length = 490
Score = 225 bits (574), Expect = 4e-56
Identities = 155/489 (31%), Positives = 241/489 (49%), Gaps = 13/489 (2%)
Frame = -2
Query: 1653 ILAASIAIFAYVVIGRNKNTHRPPQVPYFLPWIGSAISMGKDPDAFVDSCITRYGSVFRV 1474
+L A + + Y + + + PP VPY +PW+GS+I+M +DPD F + +YGSVF V
Sbjct: 11 LLLAILFVLWYRKVRLSPRSDAPPMVPYIIPWVGSSIAMARDPDKFFANATAKYGSVFGV 70
Query: 1473 LVLGQQMTFVTDPSLISLVYRDSQHFDFSRIGRQYSLDIFGIPSDIYDSA--IRYSYAEA 1300
+G FVT P+L +++ S+ F F+ S +FG+ + + +
Sbjct: 71 QAVGFYRYFVTHPTLAKQIHKMSKQFVFTPYRIHLSNKVFGMEKSTLEGTPFFEQEFFDT 130
Query: 1299 QHRALLP----QSVRPLLRQYTEQAHKLFLEAIDRADGTSVDLSSFLIPPTYCSAATTML 1132
HR L P + + P +Y Q L+L + + V L + +++
Sbjct: 131 VHRLLAPNEILKKIVPTYAKYASQEVALYLPS-----SSPVPARDLLYKMLFRASSFAFF 185
Query: 1131 GKEFPAEKSMPFFQAFDKDFPLMAAGLPRIVTRQARQAWDKLIDILREYMEAVEHEQDIP 952
G F A+ + F AFDK PL + +T +QAWD ++ +R Y+E +
Sbjct: 186 GPTFDADGCVDDFVAFDKALPLRMLNVFWPLTIPGQQAWDGIMKHMRNYVENTGAKGG-- 243
Query: 951 EILRNPIHYAREGKWPLRVAASLLGVVLWALSANAPWVAYWLIVHAVQEPLGLTPLQEEV 772
+ + +AR + A L +LWAL ANAP AYW IV + GL PL EV
Sbjct: 244 DYMEYMADHARTHNVDHEIPALAL-TLLWALEANAPLAAYWAIVLTLFHEDGLKPLYTEV 302
Query: 771 DHARKQWLASQPGTRLTSENFHDFIIESTDNFPLVTSVINETLRYTSASASLREVRAPVE 592
D R W + P T +N F+ ++ N PL+++ I ETLRYT++S S+R V P
Sbjct: 303 DAERAAWEGANP-TLSVVKNPDFFVAQA--NLPLLSATIQETLRYTASSFSIRRVVEPTT 359
Query: 591 LGGYHFETGEKVMVSARPVHMDENIHPDPRSFKMDRYV--DFQTP--QKDGKLVTN--HT 430
LGGY+F+ GE+++V+ R D +P+ +F+ R++ Q P ++ KLV + T
Sbjct: 360 LGGYNFQIGEELVVNGRSSQTDGQYYPNADTFEPTRFLVSSDQAPIGKEKEKLVNSPAFT 419
Query: 429 LPFGGGVSMCTGRHFAXXXXXXXXXXXLTYATIEVDPSSSQRP-SFDWGRFGSGMLSAKG 253
FGGGVSMC GRHFA LT+ I + P + D R G G++ KG
Sbjct: 420 AHFGGGVSMCEGRHFAQTELKVFIVLMLTHLDISLAPGAKPGDVVLDATRIGLGVIHPKG 479
Query: 252 DMRVIIKKR 226
D+ ++ +KR
Sbjct: 480 DVMLVARKR 488
>ref|XP_007361145.1| hypothetical protein DICSQDRAFT_48897 [Dichomitus squalens LYAD-421
SS1] gi|395333506|gb|EJF65883.1| hypothetical protein
DICSQDRAFT_48897 [Dichomitus squalens LYAD-421 SS1]
Length = 352
Score = 182 bits (461), Expect = 5e-43
Identities = 117/326 (35%), Positives = 167/326 (51%), Gaps = 12/326 (3%)
Frame = -2
Query: 1629 FAYVVIG--------RNKNTHRPPQVPYFLPWIGSAISMGKDPDAFVDSCITRYGSVFRV 1474
FA V++G R ++ R P+ PY++PW+G+A MGKDPD F S R+
Sbjct: 24 FALVLVGPYWAQNIIRGADSSRLPRTPYWIPWVGNAAEMGKDPDGFFTS------PSVRI 77
Query: 1473 LVLGQQMTFVTDPSLISLVYRDSQHFDFSRIGRQYSLDIFGIPSDIYDSAIRY-SYAEAQ 1297
L L Q +T LIS VYRDSQ+FDF + + F I + + + SY A
Sbjct: 78 LCLVQDFYVLTLRQLISQVYRDSQNFDFLAVRIEIGRQAFSIDDRVGTTPYMFDSYMPAL 137
Query: 1296 HRA---LLPQSVRPLLRQYTEQAHKLFLEAIDRADGTSVDLSSFLIPPTYCSAATTMLGK 1126
H LLP S++ + Y + AH + AI DG S L + +I P Y +AA +G
Sbjct: 138 HHTHHILLPVSIKTMTSTYLQSAHDTLVGAISSLDGASGPLKTIIILPAYRAAAHAGVGP 197
Query: 1125 EFPAEKSMPFFQAFDKDFPLMAAGLPRIVTRQARQAWDKLIDILREYMEAVEHEQDIPEI 946
E AEK+ F FD+ ++ A LPR ++R+ +AW+ + DI++ Y E EH+ D+ E
Sbjct: 198 ELSAEKAWKGFTTFDESVHMINASLPRSLSRKPLKAWEGVTDIIQAYPE--EHKDDVHEP 255
Query: 945 LRNPIHYAREGKWPLRVAASLLGVVLWALSANAPWVAYWLIVHAVQEPLGLTPLQEEVDH 766
P R ++L LWAL ANA W A+ I +Q+P GL PL E+D
Sbjct: 256 SPVPSGCTE------RDIFAILATRLWALHANAIWAAHKPIAELLQQPDGLAPLVAELDA 309
Query: 765 ARKQWLASQPGTRLTSENFHDFIIES 688
RKQW A+ P T L+ F D I+ +
Sbjct: 310 VRKQWQAAHPFTPLSPAFFDDVIVSA 335
>gb|EUC63789.1| cytochrome P450 family protein [Rhizoctonia solani AG-3 Rhs1AP]
Length = 509
Score = 174 bits (441), Expect = 1e-40
Identities = 129/462 (27%), Positives = 204/462 (44%), Gaps = 6/462 (1%)
Frame = -2
Query: 1590 RPPQVPYFLPWIGSAISMGKDPDAFVDSCITRYGSVFRVLVLGQQMTFVTDPSLISLVYR 1411
RPP V +++PW+GSA+ + +DPDA G VF V G + ++ D LI+ VY+
Sbjct: 71 RPPIVSHWIPWLGSALQVQRDPDALFWRAHRELGPVFGVKSFGSVVYYIADTDLINSVYK 130
Query: 1410 DSQHFDFSRIGRQYSLDIFGIPSDIY---DSAIRYSYAEAQHRALLPQSVRPLLRQYTEQ 1240
+ F S + + +F + +I + I +++R + P +V L+ +
Sbjct: 131 QTSVFSGSPMQATFLNTVFDMRMEIITGPHAGIFGDMLASKNRHISPVNVHNLVSTFISH 190
Query: 1239 AHKLFLEAIDRADGTSVDLSSFLIPPTYCSAATTMLGKEFPAEKSMPFFQAFDKDFPLMA 1060
L + R S+ L L+ + + G F F+ FD+ +A
Sbjct: 191 TRAL----VSRLHSGSMQLEE-LVTLMQKADCAMLFGSSFDFGAIASAFEKFDRGVVNLA 245
Query: 1059 AGLPRIVTRQARQAWDKLIDILREYMEAVEHEQDIPEILRNPIHYAREGKWPLRVAASLL 880
P I RQ A +L+ L +Y E E D + L++ + A+ +W R AS
Sbjct: 246 INFPLIFMRQTTAARSQLLGQLTKYFERGARE-DASQQLKDFVDLAKSAEWTERDTASFA 304
Query: 879 GVVLWALSANAPWVAYWLIVHAVQEPLGLTPLQEEVDHARKQWLASQPGTRLTSENFHDF 700
++W L ANAPW +WL+V+ + GL P+ EEV Q G L
Sbjct: 305 LGMMWPLLANAPWAVWWLLVYHLHRARGLEPILEEVKQ------VVQSGRDLVE------ 352
Query: 699 IIESTDNFPLVTSVINETLRYTSASASLREV---RAPVELGGYHFETGEKVMVSARPVHM 529
++ + P + + INET+R S S S+R V P LG + F+ G++++ R VHM
Sbjct: 353 VVRDSSATPYLDASINETIRIASDSFSVRWVPPSPTPARLGTFLFKGGDQIICKMRGVHM 412
Query: 528 DENIHPDPRSFKMDRYVDFQTPQKDGKLVTNHTLPFGGGVSMCTGRHFAXXXXXXXXXXX 349
D N++ P F+ R+ + V PFGGG S+C GRH A
Sbjct: 413 DPNVYAQPEVFEPRRFAGGKED------VRGRFFPFGGGFSICEGRHLALSQIKAFLIIF 466
Query: 348 LTYATIEVDPSSSQRPSFDWGRFGSGMLSAKGDMRVIIKKRK 223
L+ + + S S P F G GM+ G + V I +RK
Sbjct: 467 LSEFDLSLVDSQSMIPKFSPSNRGFGMIRPVGGVEVKIARRK 508
>gb|ELU37886.1| cytochrome P450 domain-containing protein [Rhizoctonia solani AG-1
IA]
Length = 552
Score = 162 bits (409), Expect = 6e-37
Identities = 129/469 (27%), Positives = 198/469 (42%), Gaps = 10/469 (2%)
Frame = -2
Query: 1599 NTHRPPQVPYFLPWIGSAISMGKDPDAFVDSCITRYGSVFRVLVLGQQMTFVTDPSLISL 1420
N RPP +++PW+GSA+ + +DPDA GSVF + G M ++TD LI+
Sbjct: 112 NEGRPPIYSHWVPWLGSALQIQRDPDALFRRAHRELGSVFGIKSFGSVMYYITDADLINS 171
Query: 1419 VYRDSQHFDFSRIGRQYSLDIFGIPSDIYDSAIRYSYAEAQHRALLPQSVRPLLRQYTEQ 1240
VY+ + F S + + +F +R H + V R
Sbjct: 172 VYKQTSVFSGSPMQATFLHSVFN---------MRMEVINGPHAGVFGDMVASKNRCGPPV 222
Query: 1239 AHKLFLEAIDRADGTSVDLSSFLIPPTYCSAATTMLGKEFPAEKSMPFFQAFDKDFPLMA 1060
+ + SV L +I T +LG F F+ FD L+A
Sbjct: 223 LDSPPYDLVSELSSGSVKLQDLVILMQKAD-CTMLLGSSFDFGSIASAFEKFDHGVTLLA 281
Query: 1059 AGLPRIVTRQARQAWDKLIDILREYMEAVEHEQDIPEILRNPIHYAREGKWPLRVAASLL 880
P + R+ A +LID L Y E+ E D + +++ + A+ +W R S
Sbjct: 282 INFPSMFMRETTAARSQLIDSLNRYFESGPPE-DASQQVKDFVDLAKGAEWTNRDTGSFA 340
Query: 879 GVVLWALSANAPWVAYWLIVHAVQEPLGLTPLQEEVDHARKQWLASQPGTRLTSENFHDF 700
++W L ANAPW +WL+V+ + + GL L EEV + S+
Sbjct: 341 LGMVWPLLANAPWAVWWLLVYHLHKARGLELLLEEVRRV------------VNSDRDLLE 388
Query: 699 IIESTDNFPLVTSVINETLRYTSASASLREV---RAPVELGGYHFETGEKVMVSARPVHM 529
++ + P + + INET+R S S S+R V P LG + F G+ VM R VHM
Sbjct: 389 VVRDSTATPYLDASINETIRIASDSWSVRWVPPSPTPSRLGTFIFRGGDLVMCKMRGVHM 448
Query: 528 DENIHPDPRSFKMDRYVDFQTPQKDGKLVTNHTLPFGGGVSM-------CTGRHFAXXXX 370
D N++ P ++ R+ T K+G + PFGGG S+ C GRH A
Sbjct: 449 DPNVYAHPEVYEPGRF----TSGKEG--MRGRFFPFGGGFSIVSPRPPSCEGRHLALSQI 502
Query: 369 XXXXXXXLTYATIEVDPSSSQRPSFDWGRFGSGMLSAKGDMRVIIKKRK 223
L + + S S+ P F G GM+ D++V + +RK
Sbjct: 503 RAFLIIFLNEFDVSLVDSQSEVPMFSPRNRGFGMIRPVRDVQVRLTRRK 551
>ref|XP_007315026.1| hypothetical protein SERLADRAFT_459654 [Serpula lacrymans var.
lacrymans S7.9] gi|336374725|gb|EGO03062.1| hypothetical
protein SERLA73DRAFT_176582 [Serpula lacrymans var.
lacrymans S7.3] gi|336387682|gb|EGO28827.1| hypothetical
protein SERLADRAFT_459654 [Serpula lacrymans var.
lacrymans S7.9]
Length = 514
Score = 157 bits (398), Expect = 1e-35
Identities = 137/519 (26%), Positives = 224/519 (43%), Gaps = 43/519 (8%)
Frame = -2
Query: 1653 ILAASIAIFAYVVIG-----RNKNTH-----RPPQVPYFLPWIGSAISMGKDPDAFVDSC 1504
IL + A+ A V++G R +NT RPP +PW+G+A+ P +
Sbjct: 3 ILDLNTAVVAVVLLGLTVWLRRRNTSPNAVIRPPYAFSLIPWVGNALDYKNRPATWTREV 62
Query: 1503 ITRYGSVFRVLVLGQQMTFVTDPSLISLVYRDSQHFDFSRIGRQYSLDIFGIPSD-IYDS 1327
++ G V++ VLG+ + F +LIS ++++ + F F+ I +FG+ D + D
Sbjct: 63 ESKLGPVYQSTVLGKPVIFCLSRTLISQIFKNYRDFSFTPIKTDAHHRVFGVTLDALSDE 122
Query: 1326 AIRYSYAEAQHRALLPQSVRPLLRQYTEQAHKLFLEAI------DRADGTSVDLSSFLIP 1165
+ + +R L ++ P++ Q + F I +R DG +L S + P
Sbjct: 123 EGQKTMFAELYRVLSKKAFGPMVGQISANMEARFSAIIGNMTPNERRDGKLFNLMSLIPP 182
Query: 1164 PTYCSAATTMLGKEFPAEKSMPFFQAFDKDFPLMAAGLP-RIVTRQARQAWDKLIDILRE 988
Y ++A M G FPA+ F+ F LM GLP + ++ D I ++
Sbjct: 183 LFYAASAQGMFGDTFPADDIFKSNTDFEDQFGLMYTGLPFPWLVKRGITGRDYCIARVKA 242
Query: 987 YMEAVEH-EQDIPEILRNPIHYAREGKWPLRVAASLLGVVLWALSANAPWVAYWLIVHAV 811
+ E E P ++ + W + A+ L L+AL++N + AYWL+V+
Sbjct: 243 SLAQYESGEVQAPYFIQVMLDLRHTLGWTSQDLAAYLHSYLFALTSNTIYAAYWLVVYTY 302
Query: 810 QEPLGLTPLQEEVDHARKQWLASQPGTRLTSENFHDFIIESTDNFPLVTSVINETLRYTS 631
P + +Q EVD A +L P + T + + DNFPL+ S+INE+LR S
Sbjct: 303 THPEVVAEIQAEVDRAEAAFLKENP--KETPTDLFANLGFLDDNFPLLNSIINESLRLCS 360
Query: 630 ASASLREVRA------------PVELGGYHFETGEKVMVSARPVHMDENIHPDPRSFKMD 487
S+REV A P E F+ G+ + + R H + D SF
Sbjct: 361 NGTSVREVMADIVMDVPSNSHGPSESRAMLFKKGDTIYMPNRYHHWNPEEFEDAESFVAT 420
Query: 486 RYVDFQTPQKDGKLVTNHTLPFGGGVSMCTGRHFAXXXXXXXXXXXLTYATIEV------ 325
R++ Q Q +PFGGG+S+C+GRH A + ++
Sbjct: 421 RFMPGQKRQ------PGFFMPFGGGISVCSGRHLASAELKALMIILTRWYNVKYECLVDR 474
Query: 324 ------DPSSSQRPSFDWGRFGSGMLSAKGDMRVIIKKR 226
D P FD G GS +L +GD+ V ++ R
Sbjct: 475 NGEKVKDAKPLAIPPFDLGS-GSAILHPEGDVVVRLRAR 512
>ref|XP_003759804.1| PREDICTED: cholesterol 7-alpha-monooxygenase-like [Sarcophilus
harrisii]
Length = 506
Score = 151 bits (382), Expect = 8e-34
Identities = 131/506 (25%), Positives = 225/506 (44%), Gaps = 26/506 (5%)
Frame = -2
Query: 1686 MENISAELTWLILAASIAIFAYVVIG-RNKNTHRPPQVPYFLPWIGSAISMGKDPDAFVD 1510
M IS L W + A + +++IG R + PP +P++G A+ G +P F+
Sbjct: 1 MLTISISLIWGFVVA-VCCCLWLIIGIRRRRLGEPPLDNGLIPYVGCALQFGANPLEFLR 59
Query: 1509 SCITRYGSVFRVLVLGQQMTFVTDPSLISLVYRDSQHFDFSRIGRQYSLDIFGIPS-DIY 1333
+ +YG +F ++G+ + F+T+P + V R ++FD+ +I S FG S D
Sbjct: 60 TKKRKYGHIFTCKLMGKYVHFITNPFSYNTVLRHGKYFDWKKINYATSAKAFGHRSIDPS 119
Query: 1332 DSAIRYSYAEAQHRALLPQSVRPLLRQYTEQAHKLF----LEAIDRADGTSVDLSSFLIP 1165
D + E + L ++ L E + L + + + SF
Sbjct: 120 DGNTTENVHETLIKTLQGDALNSLTEAMMENLQYVMKPSVLSKTNPDSWVTEGMCSFCYR 179
Query: 1164 PTYCSAATTMLGKEFPAEK--------SMPFFQAFDKDFPLMAAGLPRIVTRQARQAWDK 1009
+ + T+ GK+ ++ S+ F+ FDK FP + AGLP V + A A +K
Sbjct: 180 VMFEAGYLTLFGKDLTRQEVQRTFILNSLNNFKQFDKIFPALVAGLPIHVFKNAHNAREK 239
Query: 1008 LIDILREYMEAVEHEQDIPEIL--RNPIHYAREGKWPLRVAASLLGVVLWALSANAPWVA 835
L + LR E ++ +I E++ R ++ + A + L +LWA AN
Sbjct: 240 LAETLRH--ENLQKRDNISELITTRMFLNDTLSTFDDMEKAKTHL-ALLWAAQANTLPAT 296
Query: 834 YWLIVHAVQEPLGLTPLQEEVDHARKQWLASQPGTRLTSENFHDFIIE-STDNFPLVTSV 658
+W + H ++ P + EEV RK G +++ E + + ++ P++ S+
Sbjct: 297 FWCLFHTIRSPEAMKTATEEV---RK--TLENSGQKISFEGKPISLSQMQLNDMPVLDSI 351
Query: 657 INETLRYTSASASLREVRAP----VELGGYHFETGEKVMVSARPVHMDENIHPDPRSFKM 490
I E LR SAS ++R + +E G Y + + + +H D I+PDP FK
Sbjct: 352 IKEALRLCSASLNIRAAKEDFTLHLEEGSYSIRKDDIIAFYPQLLHFDPEIYPDPLVFKY 411
Query: 489 DRYVDFQTPQK-----DGKLVTNHTLPFGGGVSMCTGRHFAXXXXXXXXXXXLTYATIEV 325
DRY+D K +G + + +PFG G+S+C GR FA L+Y +++
Sbjct: 412 DRYLDENGKPKTNFYYNGIKLKYYYMPFGSGLSLCPGRLFAVHEIKQFLILMLSYFEMKL 471
Query: 324 DPSSSQRPSFDWGRFGSGMLSAKGDM 247
S + P D R G G+L D+
Sbjct: 472 VDSQVKYPPLDQSRLGLGILPPTNDI 497
>ref|XP_002758974.1| PREDICTED: cholesterol 7-alpha-monooxygenase [Callithrix jacchus]
Length = 504
Score = 150 bits (379), Expect = 2e-33
Identities = 126/503 (25%), Positives = 224/503 (44%), Gaps = 26/503 (5%)
Frame = -2
Query: 1677 ISAELTWLILAASIAIFAYVVIGRNKNTHRPPQVPYFLPWIGSAISMGKDPDAFVDSCIT 1498
++ L W I A+ ++ R + T PP +P++G A+ G +P F+ +
Sbjct: 2 VTISLIWGIAIAACCCLWLILGIRRRQTGEPPLENGLIPYLGCALQFGANPLEFLRANQR 61
Query: 1497 RYGSVFRVLVLGQQMTFVTDPSLISLVYRDSQHFDFSRIGRQYSLDIFGIPS-DIYDSAI 1321
++G VF ++G+ + F+T+P V ++FD+ + S FG S D D
Sbjct: 62 KHGHVFTCKLMGKYVHFITNPLSYHKVLCHGKYFDWKKFHFATSAKAFGHGSIDPRDGNT 121
Query: 1320 RYSYAEAQHRALLPQSVRPLLRQYTEQAHKLFLEAIDRADGTSV----DLSSFLIPPTYC 1153
+ + L ++ L E ++ + TS + SF +
Sbjct: 122 TENINNTFIKTLQGNALNSLTESMMENLQRIMRPPVFSNSKTSAWVTEGMYSFCYRVMFE 181
Query: 1152 SAATTMLGKEFPAE--------KSMPFFQAFDKDFPLMAAGLPRIVTRQARQAWDKLIDI 997
+ T+ G++ ++ ++ F+ FDK FP + AGLP + R A A +KL +
Sbjct: 182 AGYLTLFGRDLTSQDTQRAHILNNLDNFKQFDKVFPALVAGLPIHMFRTAHNAREKLAES 241
Query: 996 LREYMEAVEHEQDIPEI--LRNPIHYAREGKWPLRVAASLLGVVLWALSANAPWVAYWLI 823
LR E ++ ++ E+ LR ++ L A + L V+LWA AN +W +
Sbjct: 242 LRH--ENLKKRGNVSELVSLRMFLNDTLSTFNDLEKAKTHL-VILWASQANTIPATFWSL 298
Query: 822 VHAVQEPLGLTPLQEEVDHARKQWLASQPGTRLTSENFHDFIIEST--DNFPLVTSVINE 649
H ++ P + EEV G +++ E + + T ++ P++ S+I E
Sbjct: 299 FHMIRNPEAMKAATEEVKRT-----LENAGQKVSLEG-NPICLSQTQMNDLPVLDSIIKE 352
Query: 648 TLRYTSASASLREVRAP----VELGGYHFETGEKVMVSARPVHMDENIHPDPRSFKMDRY 481
+LR +SAS ++R + +E G Y+ + + + + +H+D I+PDP SFK DRY
Sbjct: 353 SLRLSSASLNIRTAKEDFTLLLEDGSYNIRKDDIIALYPQLMHLDPEIYPDPSSFKYDRY 412
Query: 480 VDFQTPQK-----DGKLVTNHTLPFGGGVSMCTGRHFAXXXXXXXXXXXLTYATIEVDPS 316
+D K +G + H +PFG G ++C GR FA L+Y +E+
Sbjct: 413 LDENGKTKTTFYCNGLKLKCHYMPFGSGATICPGRLFAIHEIKQFLILMLSYFELELVEG 472
Query: 315 SSQRPSFDWGRFGSGMLSAKGDM 247
++ P D R G G+L D+
Sbjct: 473 QAKCPPLDQSRAGLGILPPLNDI 495
>ref|XP_002936154.1| PREDICTED: cholesterol 7-alpha-monooxygenase-like [Xenopus (Silurana)
tropicalis]
Length = 513
Score = 149 bits (377), Expect = 3e-33
Identities = 127/510 (24%), Positives = 230/510 (45%), Gaps = 33/510 (6%)
Frame = -2
Query: 1677 ISAELTWLILAASIAIFAYVVIGRNKNTHRPPQVPYFLPWIGSAISMGKDPDAFVDSCIT 1498
++ L W ++ A F +V R + PP +P++G A+ G +P F+
Sbjct: 2 LTVSLIWGLVVALCCFFWLIVGIRRRQPGEPPLENGLIPYLGCALQFGANPLEFLRVRQN 61
Query: 1497 RYGSVFRVLVLGQQMTFVTDPSLISLVYRDSQHFDFSRIGRQYSLDIFGIPS-DIYDSAI 1321
++G+VF + GQ + FVTDP + V R +HFD+ + S FG + D DS +
Sbjct: 62 KFGNVFTCKIAGQFVHFVTDPFSFNSVMRHGRHFDWQKFHFATSAKAFGHSNIDSSDSEV 121
Query: 1320 RYSYAEAQHRALLPQSVRPLLRQYTEQAHKLFLE----AIDRADGTSVDLSSFLIPPTYC 1153
+ ++ + L ++ PL+ E L+ ++ D + L +F +
Sbjct: 122 TQNVHDSFLKTLQGDALDPLISNMMENLQHTMLQNSSYKVNSKDWVTEGLYAFCYRVMFE 181
Query: 1152 SAATTMLGKEF--PAEKSM--------------PFFQAFDKDFPLMAAGLPRIVTRQARQ 1021
+ T+ GKEF P +K++ F+ FDK FP + AGLP V + A
Sbjct: 182 AGYLTLFGKEFNSPEDKNLARQEAQRALILNAIENFKEFDKIFPALVAGLPIHVFKSAYS 241
Query: 1020 AWDKLI-DILREYMEAVEHEQDIPEILRNPIHYAREGKWPLRVAASLLGVVLWALSANAP 844
A + L D+L E + + ++ LR ++ + + A + L +LWA AN
Sbjct: 242 ARENLAKDLLHENLRKRNNISELIS-LRMFLNESMTSLNDMEKAKTHL-ALLWASQANTL 299
Query: 843 WVAYWLIVHAVQEPLGLTPLQEEVDHARKQWLASQPGTRLTSENFHDFI-IESTDNFPLV 667
+W + + ++ P + EEV ++ ASQ ++ + + F+ D+ P++
Sbjct: 300 PATFWSVFYLLRCPHAMKASTEEVQRVLEK--ASQ---KVNCDGRYIFLNRHELDDMPVL 354
Query: 666 TSVINETLRYTSASASLREVRAPVEL-----GGYHFETGEKVMVSARPVHMDENIHPDPR 502
S+I E +R +SAS ++R + L ++ + V + + VH++ +I+ DP
Sbjct: 355 DSIIKEAMRLSSASLNIRVAKENFVLHIDDKQAFNIRKDDIVALYPQMVHLNPDIYEDPN 414
Query: 501 SFKMDRYVDFQTPQK-----DGKLVTNHTLPFGGGVSMCTGRHFAXXXXXXXXXXXLTYA 337
+FK DRY+ +K +G+ + + +PFG G + C GR FA + Y
Sbjct: 415 NFKYDRYLGEDGKEKTSFFLNGRKLKYYYMPFGSGKTKCPGRQFAVHEIKQMLTLIICYF 474
Query: 336 TIEVDPSSSQRPSFDWGRFGSGMLSAKGDM 247
+E+ + + P D R G G+L D+
Sbjct: 475 DMELVDKNIRSPPLDQSRAGLGILQPTHDV 504
>ref|XP_006113686.1| PREDICTED: cholesterol 7-alpha-monooxygenase-like [Pelodiscus
sinensis]
Length = 509
Score = 149 bits (375), Expect = 5e-33
Identities = 124/508 (24%), Positives = 218/508 (42%), Gaps = 31/508 (6%)
Frame = -2
Query: 1677 ISAELTWLILAASIAIFAYVVIGRNKNTHRPPQVPYFLPWIGSAISMGKDPDAFVDSCIT 1498
++A L W ++ F ++++ R + PP LP++G A+ G +P F+ +
Sbjct: 2 LAAALIWGVVVILCCWFWFILVIRRRRPGEPPVENGLLPYLGCALQFGANPLEFLKARQK 61
Query: 1497 RYGSVFRVLVLGQQMTFVTDPSLISLVYRDSQHFDFSRIGRQYSLDIFGIPSDIYDSAIR 1318
+YG +F V G+ + F+TDP V R +H D+ + S FG S D
Sbjct: 62 KYGHIFTCKVAGKYVHFLTDPFSYHSVMRQGRHLDWKKFHFTASAKAFGHGS--IDGNTT 119
Query: 1317 YSYAEAQHRALLPQSVRPLLRQYTEQAHKLFLEA----IDRADGTSVDLSSFLIPPTYCS 1150
+ + R L ++ L E + L++ + + + L +F + S
Sbjct: 120 ENMHKTFIRTLQGNALNSLTEAMMENLQYVMLQSSTSELHSNNWVTEGLYAFCCRVMFES 179
Query: 1149 AATTMLGKEFPAEK----------------SMPFFQAFDKDFPLMAAGLPRIVTRQARQA 1018
T+ G EF + + ++ F+ FDK FP + AG+P V + A A
Sbjct: 180 GFLTLFGTEFNSSQDRHLSQGETQRELILNALENFKTFDKIFPALVAGVPIHVFKSAHNA 239
Query: 1017 WDKLIDILREYMEAVEHEQDIPEILRNPIHYARE-GKWPLRVAASLLGVVLWALSANAPW 841
+KL + L E + ++ E++ + + + A VLWA AN
Sbjct: 240 REKLAEALLH--ENLRKRNNLSELVTLRMFLNDTLSTFDDKEKAKTHVAVLWASQANTIP 297
Query: 840 VAYWLIVHAVQEPLGLTPLQEEVDHARKQWLASQPGTRLTSENFH-DFIIESTDNFPLVT 664
+W + + ++ P + EE+ Q G ++T + H + DN P++
Sbjct: 298 ATFWSLFYLIRSPEAMKAATEEL-----QKTLESAGEKITLDGKHISLDRKQMDNMPVLD 352
Query: 663 SVINETLRYTSASASLREVRAPVEL----GGYHFETGEKVMVSARPVHMDENIHPDPRSF 496
S+I E +R +SAS ++R L Y+ + V + + +H D +I+PDP +F
Sbjct: 353 SIIKEAMRLSSASMTVRVANEDFTLHLDNDSYNIRKDDVVALYPQLLHFDPDIYPDPLTF 412
Query: 495 KMDRYVDFQTPQK-----DGKLVTNHTLPFGGGVSMCTGRHFAXXXXXXXXXXXLTYATI 331
K +RY+D +K +G + + +PFG G++ C GR FA L+Y I
Sbjct: 413 KYNRYLDETGEEKTNFYRNGHKLRYYYMPFGTGIAKCPGRLFAVHEIKQFLILVLSYFEI 472
Query: 330 EVDPSSSQRPSFDWGRFGSGMLSAKGDM 247
E+ + PS D R G G+L D+
Sbjct: 473 ELLDKNVACPSLDQSRAGLGILQPTNDI 500
>ref|XP_006003627.1| PREDICTED: cholesterol 7-alpha-monooxygenase-like [Latimeria
chalumnae]
Length = 493
Score = 149 bits (375), Expect = 5e-33
Identities = 125/483 (25%), Positives = 212/483 (43%), Gaps = 37/483 (7%)
Frame = -2
Query: 1569 FLPWIGSAISMGKDPDAFVDSCITRYGSVFRVLVLGQQMTFVTDPSLISLVYRDSQHFDF 1390
++P+ G AI G DP F++S +YGS F + G+ +TF+TDP S V R + DF
Sbjct: 19 WIPFFGVAIQFGADPLKFLNSRKKKYGSTFTCKIAGKYLTFITDPFSYSSVIRHGKSLDF 78
Query: 1389 SRIGRQYSLDIFGIPSDIYDSAIRYSYAEAQH---RALLPQSVRPLLRQYTEQAHKLFLE 1219
+ + S + FG D DS +Y E H + L ++ PL + H + L
Sbjct: 79 QKFALETSRNAFG-HVDFSDSKYGITYDEIHHIFLKTLQGSALGPLTQSMMANLHSVMLR 137
Query: 1218 AIDRADGTSV----DLSSFLIPPTYCSAATTMLGK-------------EFPAEKSMPFFQ 1090
D+ S+ L +F+ + + T+ GK + + ++ F+
Sbjct: 138 --DKTSSASIWTTEGLQAFVTRIIFEAGFLTLFGKNMKENTTDRLQSQQVAVQAALEDFK 195
Query: 1089 AFDKDFPLMAAGLPRIVTRQARQAWDKLIDILREYMEAVEHEQDIPEILRNPIHYAREGK 910
FD FP + AG+P + A++A + L + R ++ + + ++ I
Sbjct: 196 KFDMAFPALVAGVPISFLQGAKKAREALAE--RFLPMKMKQNECVSSLIEQRIKLFDSSP 253
Query: 909 WPLRVAASLLGVV-LWALSANAPWVAYWLIVHAVQEPLGLTPLQEEVDHARKQWLASQPG 733
V + V+ LWA AN +W + ++ P L +++E+D+
Sbjct: 254 HLSEVTKARTHVIMLWAAQANTLPATFWSTYYLLRSPEALLAVRKEIDNM---------- 303
Query: 732 TRLTSENFHD------FIIESTDNFPLVTSVINETLRYTSASASLR----EVRAPVELG- 586
LT + + D F E +N P + SVI+E LR +SAS +R + ++ G
Sbjct: 304 LYLTDQKYRDATQSISFTKEQLENMPTMGSVISEALRLSSASIMIRCATEDFTLTLDSGE 363
Query: 585 GYHFETGEKVMVSARPVHMDENIHPDPRSFKMDRYVD-----FQTPQKDGKLVTNHTLPF 421
G+++ + + H+D I+ +P F+ DR++D T K+GK + ++ +PF
Sbjct: 364 KLAIRKGDRIALVPQLQHLDPEIYENPLEFQYDRFLDKTGKEKTTFYKNGKKLKHYLMPF 423
Query: 420 GGGVSMCTGRHFAXXXXXXXXXXXLTYATIEVDPSSSQRPSFDWGRFGSGMLSAKGDMRV 241
G G SMC GR FA L Y IE+ S+ D R G G+L K D+ +
Sbjct: 424 GSGTSMCPGRFFAINEIKQFLSLLLCYYDIELLDRSAPPLPLDNSRAGLGILQPKHDVGI 483
Query: 240 IIK 232
K
Sbjct: 484 RYK 486
>ref|XP_005301221.1| PREDICTED: cholesterol 7-alpha-monooxygenase-like [Chrysemys picta
bellii]
Length = 512
Score = 147 bits (370), Expect = 2e-32
Identities = 127/509 (24%), Positives = 219/509 (43%), Gaps = 32/509 (6%)
Frame = -2
Query: 1677 ISAELTWLILAASIAIFAYVVIGRNKNTHRPPQVPYFLPWIGSAISMGKDPDAFVDSCIT 1498
++A L W I+ F +++ R + PP LP++G A+ G +P F+ +
Sbjct: 2 LAASLIWGIVVILCCCFWFILGIRRRRPGEPPVENGLLPYLGCALQFGANPLEFLKARQK 61
Query: 1497 RYGSVFRVLVLGQQMTFVTDPSLISLVYRDSQHFDFSRIGRQYSLDIFGIPS-DIYDSAI 1321
+YG +F V G+ + F+TDP V R +H D+ + S FG S D D
Sbjct: 62 KYGHIFTCKVAGKYVHFLTDPFSYHSVMRQGRHLDWKKFHFAASAKAFGHGSIDPRDGNT 121
Query: 1320 RYSYAEAQHRALLPQSVRPLLRQYTEQAHKLFLEA----IDRADGTSVDLSSFLIPPTYC 1153
+ + R L ++ L+ TE + L++ + + + L +F +
Sbjct: 122 TENMHQTFIRTLQGNALNSLIEAMTENLQYVMLQSSTSKLHSNNWVTDGLYAFCCRVMFE 181
Query: 1152 SAATTMLGKEFPAEK----------------SMPFFQAFDKDFPLMAAGLPRIVTRQARQ 1021
S T+ G EF + + ++ F+ FDK FP + AG+P V + A
Sbjct: 182 SGFLTLFGTEFNSTQDKNLSQRETQRALILNALENFKEFDKIFPALVAGVPIHVFKSAHN 241
Query: 1020 AWDKLIDILREYMEAVEHEQDIPEILRNPIHYARE-GKWPLRVAASLLGVVLWALSANAP 844
A +KL + L E + +I E++ + + + A VLWA AN
Sbjct: 242 AREKLAEALLH--ENLRKRNNISELVTLRMFLNDTLSTFDDKEKAKTHLAVLWASQANTI 299
Query: 843 WVAYWLIVHAVQEPLGLTPLQEEVDHARKQWLASQPGTRLTSE-NFHDFIIESTDNFPLV 667
+W + + ++ P + EEV Q G ++ + + DN P++
Sbjct: 300 PATFWSLFYLIRSPEAMKAATEEV-----QKTLGNAGEKIDLDGKCISLNRKQLDNMPVL 354
Query: 666 TSVINETLRYTSASASLREVRAPVEL----GGYHFETGEKVMVSARPVHMDENIHPDPRS 499
S+I E +R +SAS ++R + L Y+ + V + + +H D +I+ DP +
Sbjct: 355 DSIIKEAMRLSSASMTVRVAKEDFTLHLDNDSYNIRKDDIVALYPQLLHFDPDIYADPLT 414
Query: 498 FKMDRYVDFQTPQK-----DGKLVTNHTLPFGGGVSMCTGRHFAXXXXXXXXXXXLTYAT 334
FK DRY++ +K +G + + +PFG G++ C GR FA L+Y
Sbjct: 415 FKYDRYLNENGEEKTIFYRNGHKLRYYYMPFGSGIAKCPGRLFAVHEIKQFLTLVLSYFE 474
Query: 333 IEVDPSSSQRPSFDWGRFGSGMLSAKGDM 247
IE+ S+ PS D R G G+L D+
Sbjct: 475 IELLDSNVPCPSLDQSRAGLGILQPTNDI 503
>dbj|BAN16581.1| cytochrome P450 family 7 subfamily a polypeptide 1-1 [Oncorhynchus
mykiss]
Length = 512
Score = 147 bits (370), Expect = 2e-32
Identities = 131/515 (25%), Positives = 228/515 (44%), Gaps = 38/515 (7%)
Frame = -2
Query: 1677 ISAELTWLILAASIAIFAYVVIG-RNKNTHRPPQVPYFLPWIGSAISMGKDPDAFVDSCI 1501
I+ L W ++ S ++ +G R + PP +P++G A+ G +P F+ S
Sbjct: 3 ITVSLIWFVVI-SFCCCLWLALGIRKRKPGEPPVENGLIPYLGCAVQFGANPLEFLRSRQ 61
Query: 1500 TRYGSVFRVLVLGQQMTFVTDPSLISLVYRDSQHFDFSRIGRQYSLDIFGIPSDIYDSAI 1321
+YG +F + G+ F+ DP V R +H D+ + S+ FG D D
Sbjct: 62 NKYGHIFTCKIAGKYFHFLCDPFSYHAVIRQGRHLDWKKFHFSTSVKAFG--HDSMDPRH 119
Query: 1320 RYSYAEAQH----RALLPQSVRPLLRQYTEQAHKLFLEA---IDRADGTSVD-LSSFLIP 1165
Y+ E H + L +++ L+ E + L++ D VD + +F
Sbjct: 120 GYT-TENLHQTFMKTLQGEALPSLIETMMENLQSVMLQSDTLSPSKDRWDVDGIFAFCYK 178
Query: 1164 PTYCSAATTMLGKEFPAEK--------------SMPFFQAFDKDFPLMAAGLPRIVTRQA 1027
+ S+ T+ GK+ +K ++ F+ FDK FP + AGLP V + A
Sbjct: 179 VMFESSYLTLFGKDLGNDKNAARQEAQKALVLNTLENFKEFDKIFPALVAGLPIHVFKSA 238
Query: 1026 RQAWDKLI-DILREYMEAVEHEQDIPEILRNPIHYAREGKWPLRVAASLLGVVLWALSAN 850
A + L +L E + E+ D+ LR ++ L A + + +LWA AN
Sbjct: 239 HSARENLAKTMLAENLSKRENVSDLIS-LRMLLNDTLSTFNDLSKARTHV-ALLWASQAN 296
Query: 849 APWVAYWLIVHAVQEPLGLTPLQEEV----DHARKQWLASQPGTRLTSENFHDFIIESTD 682
A+W ++H ++ P + EEV + + ++ S+P L+ E+ D
Sbjct: 297 TLPTAFWSLLHMIRSPEAMKAANEEVKNILESSGQRVDPSKPQLTLSREDL--------D 348
Query: 681 NFPLVTSVINETLRYTSASASLREVRAPVEL-----GGYHFETGEKVMVSARPVHMDENI 517
N P++ S+I E +R +SAS ++R + L Y + + + + +H D I
Sbjct: 349 NMPVIDSIIKEAMRLSSASMNIRVAKEDFLLHLDNQESYRIRKDDVIALYPQMLHFDPKI 408
Query: 516 HPDPRSFKMDRYVDFQTPQK-----DGKLVTNHTLPFGGGVSMCTGRHFAXXXXXXXXXX 352
+ DP ++K DRY+D +K +G+ + + +PFG GV+ C GR FA
Sbjct: 409 YEDPLTYKYDRYLDDNGQEKTTFYREGRKLRYYYMPFGSGVTKCPGRFFAVHEIKQFLAL 468
Query: 351 XLTYATIEVDPSSSQRPSFDWGRFGSGMLSAKGDM 247
L+Y +E+ S+ + P D R G G+L D+
Sbjct: 469 VLSYFNMELLDSAVKVPPLDQSRAGLGILQPTYDV 503
>ref|XP_002819157.1| PREDICTED: cholesterol 7-alpha-monooxygenase-like [Pongo abelii]
Length = 504
Score = 147 bits (370), Expect = 2e-32
Identities = 125/503 (24%), Positives = 223/503 (44%), Gaps = 26/503 (5%)
Frame = -2
Query: 1677 ISAELTWLILAASIAIFAYVVIGRNKNTHRPPQVPYFLPWIGSAISMGKDPDAFVDSCIT 1498
++ L W I A+ ++ R + T PP +P++G A+ G +P F+ +
Sbjct: 2 MTISLIWGIAIAACCCLWLILGIRRRQTGEPPLENGLIPYLGCALQFGANPLEFLRANQR 61
Query: 1497 RYGSVFRVLVLGQQMTFVTDPSLISLVYRDSQHFDFSRIGRQYSLDIFGIPS-DIYDSAI 1321
++G VF ++G+ + F+T+P V ++FD+ + S FG S D D
Sbjct: 62 KHGHVFTCKLMGKYVHFITNPLSYHKVLCHGKYFDWKKFHFATSAKAFGHRSIDPRDGNT 121
Query: 1320 RYSYAEAQHRALLPQSVRPLLRQYTEQAHKLFLEAIDRADGTSV----DLSSFLIPPTYC 1153
+ + + L ++ L E ++ + T+ + SF +
Sbjct: 122 TENINDTFIKTLQGNALNSLTESMMENLQRIMRPPVSSNSKTAAWVTEGMYSFCYRVMFE 181
Query: 1152 SAATTMLGKEFPAE--------KSMPFFQAFDKDFPLMAAGLPRIVTRQARQAWDKLIDI 997
+ T+ G++ + ++ F+ FDK FP + AGLP + R A A +KL +
Sbjct: 182 AGYLTIFGRDLTRQDTQKAHILNNLDNFKQFDKVFPALVAGLPIHMFRTAHNAREKLAES 241
Query: 996 LREYMEAVEHEQDIPEI--LRNPIHYAREGKWPLRVAASLLGVVLWALSANAPWVAYWLI 823
LR E ++ + I E+ LR ++ L A + L VVLWA AN +W +
Sbjct: 242 LRH--ENLQKRESISELISLRMFLNDTLSTFDDLEKAKTHL-VVLWASQANTIPATFWSL 298
Query: 822 VHAVQEPLGLTPLQEEVDHARKQWLASQPGTRLTSENFHDFIIESTD--NFPLVTSVINE 649
++ P + EEV G ++T E + + T+ + P++ S+I E
Sbjct: 299 FQMIRNPEAMKAATEEVKRT-----LENAGQKVTLEG-NPICLSQTELNDLPVLDSIIKE 352
Query: 648 TLRYTSASASLREVRAP----VELGGYHFETGEKVMVSARPVHMDENIHPDPRSFKMDRY 481
+LR +SAS ++R + +E G Y+ + + + + +H+D I+PDP +FK DRY
Sbjct: 353 SLRLSSASLNIRTAKEDFTLHLEDGSYNIRKDDIIALYPQLMHLDPEIYPDPLTFKYDRY 412
Query: 480 VDFQTPQK-----DGKLVTNHTLPFGGGVSMCTGRHFAXXXXXXXXXXXLTYATIEVDPS 316
+D K +G + + +PFG G ++C GR FA L+Y +E+
Sbjct: 413 LDENGKTKTTFYCNGLKLKYYYMPFGSGATICPGRLFAIHEIKQFLILMLSYFELELVEG 472
Query: 315 SSQRPSFDWGRFGSGMLSAKGDM 247
++ P D R G G+L D+
Sbjct: 473 QAKCPPLDQSRAGLGILPPLNDI 495
>ref|XP_006899296.1| PREDICTED: cholesterol 7-alpha-monooxygenase-like [Elephantulus
edwardii]
Length = 504
Score = 146 bits (368), Expect = 3e-32
Identities = 123/502 (24%), Positives = 221/502 (44%), Gaps = 25/502 (4%)
Frame = -2
Query: 1677 ISAELTWLILAASIAIFAYVVIGRNKNTHRPPQVPYFLPWIGSAISMGKDPDAFVDSCIT 1498
I+ L W I+ + R + T PP F+P++G A+ G +P F+ +
Sbjct: 2 ITVSLIWGIVVVMCCCLWLFLGVRRRKTGEPPLENGFIPYLGCALQFGANPLEFLRANQR 61
Query: 1497 RYGSVFRVLVLGQQMTFVTDPSLISLVYRDSQHFDFSRIGRQYSLDIFGIPS-DIYDSAI 1321
++G VF ++G+ + F+T+P V +HFD+ + S +FG S D D
Sbjct: 62 KHGHVFTCQLMGKYVHFITNPLSFHKVLSHGKHFDWRKFHFTTSAKVFGHRSVDPSDGHT 121
Query: 1320 RYSYAEAQHRALLPQSVRPLLRQYTEQAHKLFLEAI----DRADGTSVDLSSFLIPPTYC 1153
+ + L ++ PL E ++ ++ A + + SF +
Sbjct: 122 TENINNTFIKTLQGDALNPLAEAMLENLQRIMRPSVPAEPKHAAWVTEGMYSFCYRVMFE 181
Query: 1152 SAATTMLGKEFPAEKS--------MPFFQAFDKDFPLMAAGLPRIVTRQARQAWDKLIDI 997
+ T+ G++ ++S + F+ FDK FP + AGLP + + A A +KL +
Sbjct: 182 AGYLTLFGEDLTRQESHRALMLSNLDNFKEFDKIFPALVAGLPIHMFKAAHHAREKLAED 241
Query: 996 LR-EYMEAVEHEQDIPEILRNPIHYAREGKWPLRVAASLLGVVLWALSANAPWVAYWLIV 820
LR E + + D+ LR ++ + A + L V+LWA AN +W +
Sbjct: 242 LRHENLRKRDRLSDLVS-LRMLLNDQLSTFDDMEKAKTHL-VLLWASQANTIPATFWSLF 299
Query: 819 HAVQEPLGLTPLQEEVDHARKQWLASQPGTRLTSENFHDFIIEST--DNFPLVTSVINET 646
H ++ P + EEV+ G ++ E + + T + P++ S+I E+
Sbjct: 300 HLIRSPEAMKAAAEEVNKT-----LENAGQKIQFEG-NPICLNQTQLNGMPILDSIIKES 353
Query: 645 LRYTSASASLREVRAP----VELGGYHFETGEKVMVSARPVHMDENIHPDPRSFKMDRYV 478
LR +SAS ++R + +E ++ + + + +H+D I+PDP +FK DRY+
Sbjct: 354 LRLSSASLNIRAAKEDFALHIEDKSFNIRKDDFIAFYPQLMHLDPEIYPDPLTFKYDRYL 413
Query: 477 DFQTPQK-----DGKLVTNHTLPFGGGVSMCTGRHFAXXXXXXXXXXXLTYATIEVDPSS 313
D K +G + + +PFG G ++C GR FA ++Y +E+ S
Sbjct: 414 DENGKAKTTFYSNGLKLKYYYMPFGSGATICPGRLFAVHEIKQFLILMISYFELELVDSK 473
Query: 312 SQRPSFDWGRFGSGMLSAKGDM 247
+ P D R G G+L D+
Sbjct: 474 IKCPPLDQSRAGLGILPPLNDI 495
>ref|XP_005362416.1| PREDICTED: 25-hydroxycholesterol 7-alpha-hydroxylase-like [Microtus
ochrogaster]
Length = 563
Score = 146 bits (368), Expect = 3e-32
Identities = 123/444 (27%), Positives = 199/444 (44%), Gaps = 23/444 (5%)
Frame = -2
Query: 1587 PPQVPYFLPWIGSAISMGKDPDAFVDSCITRYGSVFRVLVLGQQMTFVTDPSLISLVYRD 1408
PP + +LP++G + + KDP AF+ + +YG F VL+ G+ +TFV +P L+ ++
Sbjct: 100 PPLIKGWLPYLGITLKLQKDPLAFIKTLQRKYGDTFTVLISGKYITFVLNPFQYHLIRKN 159
Query: 1407 SQHFDFSRIGRQYSLDIFGI----PSDIYDSAIRYSYAEAQHRALLPQSVRPLLRQYTEQ 1240
+ F F RQ SL F I D + I SY Q +A L + L++Q E
Sbjct: 160 PKQFSFQEFSRQLSLKAFSIKKLKTDDDLNEDIHRSYLFLQGKA-LDSLLESLIQQLKEI 218
Query: 1239 AHKLFLEAIDRADGTSVDLSSFLIPPTYCSAATTMLGKEFPAEKSMPF------FQAFDK 1078
L+ + + L F+ + + TT+ GK + F FD
Sbjct: 219 IEPQLLKT---TEWNTSRLFPFISSLVFETTFTTIYGKLLTGNRKKIISELRDDFLKFDD 275
Query: 1077 DFPLMAAGLPRIVTRQARQAWDKLID-ILREYMEAV----EHEQDIPEILRNPIHYAREG 913
FP + + +P + R + +KLI ++ E ++ + E Q+ E+L HY RE
Sbjct: 276 TFPYLISDIPIQLLRHVKSMQEKLIRCLMSEKLDQMHGCSEVVQERKELLEK--HYGRE- 332
Query: 912 KWPLRVAASLLGVVLWALSANAPWVAYWLIVHAVQEPLGLTPLQEEVDHARKQWLASQPG 733
L + A LG LWA AN YW + + ++ P + L++E+D + Q + G
Sbjct: 333 --DLEIGAHHLG-FLWASMANTIPAVYWAVYYLLRHPEAVEALRDEID-SFVQSTGQKKG 388
Query: 732 TRLTSENFHDFIIESTDNFPLVTSVINETLRYTSASASLREVRA----PVELGGYHFETG 565
L+ F E D+ + S + E LR S S +R+V +E Y G
Sbjct: 389 PGLSIH----FTREQLDSLVCLDSTVLEVLRLCSHSTIVRKVEEDMNFSLETSNYCLRKG 444
Query: 564 EKVMVSARPVHMDENIHPDPRSFKMDRYVD----FQTPQKDGKLVTNHTLPFGGGVSMCT 397
+ V + +HMD + P F+ DR+++ T K+GK + + +PFG G S C
Sbjct: 445 DFVAIFPPILHMDPEVFEAPEEFRFDRFLEDGKKKTTFLKEGKKLKYYIMPFGFGASKCP 504
Query: 396 GRHFAXXXXXXXXXXXLTYATIEV 325
GR+FA LTY +E+
Sbjct: 505 GRYFAIIEMKLLLAILLTYFDLEI 528
>ref|XP_002597173.1| hypothetical protein BRAFLDRAFT_66301 [Branchiostoma floridae]
gi|229282436|gb|EEN53185.1| hypothetical protein
BRAFLDRAFT_66301 [Branchiostoma floridae]
Length = 1154
Score = 145 bits (367), Expect = 4e-32
Identities = 127/492 (25%), Positives = 213/492 (43%), Gaps = 23/492 (4%)
Frame = -2
Query: 1668 ELTWLILAASIAIFAYVVIGRNKNTHRPPQVPYFLPWIGSAISMGKDPDAFVDSCITRYG 1489
EL + LA + V R + PP P LP++G A+ ++P F+ S +YG
Sbjct: 661 ELLGVCLAVVLVFVLLQVTTRRRRPGEPPLEPGPLPYLGVALEFSRNPLGFITSRWKKYG 720
Query: 1488 SVFRVLVLGQQMTFVTDPSLISLVYRDSQHFDFSRIGRQYSLDIFGIPSDIYDSAIRYSY 1309
VF V + G TFV DP + R+S+ DF + + FG+P +Y + +
Sbjct: 721 DVFTVRLAGHYTTFVLDPHSFTHAIRNSKVLDFRVFSSKIAHRAFGMPI-VYGT--HRDW 777
Query: 1308 AEAQHRALLPQSVRPL-LRQYTE----QAHKLFLEAIDRAD-GTSVDLSSFLIPPTYCSA 1147
A AL P+ ++ L + TE L A D D +L SF+ + ++
Sbjct: 778 VRADSDALYPKELQGQGLEKVTEVMMNNLQSAMLAATDVKDKWNKGELWSFVYRIMFSAS 837
Query: 1146 ATTMLGKEFPAEK-------SMPFFQAFDKDFPLMAAGLPRIVTRQARQAWDKLIDILRE 988
T+ G+ E+ +M FQ +DK FP + + +P + Q + K + L+
Sbjct: 838 YKTLFGRHKEDEEETARLLHAMEEFQKYDKRFPEIISNVPWWLMGQTK----KRYEYLKS 893
Query: 987 YMEAVE-HEQDIPEILRNPIHYAREGKWPLRVAASLLGVVLWALSANAPWVAYWLIVHAV 811
+ E ++ + + +R +G +WA +N A+W + + +
Sbjct: 894 MVSPTELSQRGVSDFIRMRQEIYADGNLSPDEMTGFNFATMWASLSNTVPAAFWTLFYLL 953
Query: 810 QEPLGLTPLQEEVDHARKQWLASQPGTRLTSENFHDFIIESTDNFPLVTSVINETLRYTS 631
++P+ + ++EEV+ K+ S + E H E ++ + S INE LR S
Sbjct: 954 KDPVAMDAVREEVNQILKETGQSLETVKEAGEMLH-VTREQLNDMKCLGSAINEALRMCS 1012
Query: 630 ASASLREVRAPVEL-----GGYHFETGEKVMVSARPVHMDENIHPDPRSFKMDRY----V 478
AS +R EL + G++V + +HMD + DP +FK DR+ +
Sbjct: 1013 ASIIIRVATEDAELALESGSTFRIRKGDRVALYPGFLHMDPEVFDDPETFKYDRFLENGM 1072
Query: 477 DFQTPQKDGKLVTNHTLPFGGGVSMCTGRHFAXXXXXXXXXXXLTYATIEVDPSSSQRPS 298
+ T K+G+ + ++ LPFG G SMC GR FA + Y +E+ Q P
Sbjct: 1073 EKTTFYKNGRKLRHYLLPFGHGASMCPGRFFALNEIKQFVTIVVCYFNMEL--MEKQTPP 1130
Query: 297 FDWGRFGSGMLS 262
D R G G L+
Sbjct: 1131 KDQSRAGLGTLA 1142
>ref|XP_006003615.1| PREDICTED: cholesterol 7-alpha-monooxygenase-like [Latimeria
chalumnae]
Length = 514
Score = 145 bits (366), Expect = 5e-32
Identities = 124/510 (24%), Positives = 223/510 (43%), Gaps = 33/510 (6%)
Frame = -2
Query: 1677 ISAELTWLILAASIAIFAYVVIGRNKNTHRPPQVPYFLPWIGSAISMGKDPDAFVDSCIT 1498
+S L W ++ A V+ R ++ PP ++P++G + G +P F+ +
Sbjct: 3 LSIALIWGVVVALCCCLWLVLGIRRRHPGEPPVENGYVPYLGCTLQFGTNPLEFLRARQK 62
Query: 1497 RYGSVFRVLVLGQQMTFVTDPSLISLVYRDSQHFDFSRIGRQYSLDIFGIPS-DIYDSAI 1321
+YG +F + G+ + F+TDP V R +H D+ + S+ FG S D D
Sbjct: 63 KYGHIFTCKIAGRFVHFLTDPFSYHSVIRQGRHLDWKKFHFSASVKAFGHDSMDPNDGYT 122
Query: 1320 RYSYAEAQHRALLPQSVRPLLRQYTEQAHKLFLEA----IDRADGTSVDLSSFLIPPTYC 1153
+ + + L +++ L+ E + L + ++ + + L +F +
Sbjct: 123 TENLHQTFIKTLQGDALKSLIETMMENLQYVMLHSNTLKLNSREWATDGLYAFCYKVMFE 182
Query: 1152 SAATTMLGKE--FPAEK--------------SMPFFQAFDKDFPLMAAGLPRIVTRQARQ 1021
S T+ GKE F +K ++ F+ FDK FP + AGLP V + A
Sbjct: 183 SGYLTLFGKELNFSEDKVTARLEAQRALILNALENFKEFDKIFPALVAGLPIHVFKNAHS 242
Query: 1020 AWDKLI-DILREYMEAVEHEQDIPEILRNPIHYAREGKWPLRVAASLLGVVLWALSANAP 844
A + L ++L E + + D+ LR ++ + A + + +LWA AN
Sbjct: 243 ARENLAKNLLHENLRRRNNISDLIS-LRMVLNDTLSTMNDMAKARTHV-ALLWASQANTL 300
Query: 843 WVAYWLIVHAVQEPLGLTPLQEEVDHARKQWLASQPGTRLTSENFH-DFIIESTDNFPLV 667
+W + + ++ P + EEV Q + G + + + H + E +N P++
Sbjct: 301 PATFWSLFYLIRSPEAMKAATEEV-----QKTLEKSGQKASLDGSHISLMREELNNMPVL 355
Query: 666 TSVINETLRYTSASASLREVRAPVEL-----GGYHFETGEKVMVSARPVHMDENIHPDPR 502
S+I E +R +SAS ++R + L Y + + + + +H D I+ DP
Sbjct: 356 DSIIKEAMRLSSASLNVRVAKENFTLLLDNDESYSIRKDDVIALYPQLLHFDPKIYEDPM 415
Query: 501 SFKMDRYVDFQTPQK-----DGKLVTNHTLPFGGGVSMCTGRHFAXXXXXXXXXXXLTYA 337
+FK RY+D +K DG+ + + +PFG GV+ C GR FA LTY
Sbjct: 416 TFKYGRYLDENGQEKTTFYRDGRKLKYYYMPFGSGVTKCPGRFFAVHEIKEFLTLLLTYF 475
Query: 336 TIEVDPSSSQRPSFDWGRFGSGMLSAKGDM 247
+E+ +++ P D R G G+L D+
Sbjct: 476 ELELVDKNAKCPPLDQSRAGLGILQPTHDV 505