BLASTX 2.2.26 [Sep-21-2011]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= Ophiopogon27_contig00045135
         (1691 letters)

Database: All non-redundant GenBank CDS
translations+PDB+SwissProt+PIR+PRF excluding environmental samples
from WGS projects 
           149,584,005 sequences; 54,822,741,787 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

dbj|GBC46544.1| 3-phosphoinositide dependent protein kinase-1 [R...   903   0.0  
gb|PKC07109.1| Pkinase-domain-containing protein [Rhizophagus ir...   692   0.0  
gb|ORY01027.1| kinase-like protein [Basidiobolus meristosporus C...   543   0.0  
ref|XP_004346099.1| PkB kinase [Capsaspora owczarzaki ATCC 30864...   479   e-160
ref|XP_020024613.1| 3-phosphoinositide-dependent protein kinase ...   453   e-151
ref|XP_008843764.1| PREDICTED: 3-phosphoinositide-dependent prot...   452   e-151
ref|XP_020024612.1| 3-phosphoinositide-dependent protein kinase ...   453   e-150
ref|XP_008843756.1| PREDICTED: 3-phosphoinositide-dependent prot...   452   e-150
ref|XP_004652256.1| PREDICTED: 3-phosphoinositide-dependent prot...   450   e-149
ref|XP_012867072.1| PREDICTED: 3-phosphoinositide-dependent prot...   450   e-149
ref|XP_003478169.2| 3-phosphoinositide-dependent protein kinase ...   449   e-149
ref|XP_015346357.1| PREDICTED: 3-phosphoinositide-dependent prot...   449   e-149
ref|XP_005337841.1| 3-phosphoinositide-dependent protein kinase ...   449   e-149
ref|XP_010601839.1| PREDICTED: 3-phosphoinositide-dependent prot...   449   e-149
ref|XP_007528101.1| PREDICTED: 3-phosphoinositide-dependent prot...   449   e-149
ref|XP_008061434.1| 3-phosphoinositide-dependent protein kinase ...   449   e-149
ref|XP_021089426.1| 3-phosphoinositide-dependent protein kinase ...   449   e-149
ref|XP_006979015.1| PREDICTED: 3-phosphoinositide-dependent prot...   449   e-149
ref|XP_007606614.1| PREDICTED: 3-phosphoinositide-dependent prot...   448   e-149
gb|EHA99237.1| 3-phosphoinositide-dependent protein kinase 1 [He...   448   e-149

>dbj|GBC46544.1| 3-phosphoinositide dependent protein kinase-1 [Rhizophagus
            irregularis DAOM 181602]
 gb|PKK72345.1| Pkinase-domain-containing protein [Rhizophagus irregularis]
 gb|PKY16403.1| Pkinase-domain-containing protein [Rhizophagus irregularis]
 gb|PKY50811.1| Pkinase-domain-containing protein [Rhizophagus irregularis]
 gb|POG77894.1| kinase-like domain-containing protein [Rhizophagus irregularis DAOM
            181602=DAOM 197198]
          Length = 528

 Score =  903 bits (2333), Expect = 0.0
 Identities = 444/488 (90%), Positives = 459/488 (94%), Gaps = 3/488 (0%)
 Frame = +1

Query: 7    NSQQTLKT---HTPFVRKKGVKDFEFGKTLGEGSYSTVVAARDRSNGREYAVXXXXXXXX 177
            NS+QTLKT   HTP VRKKGVKDFEFGKTLGEGSYSTVVAARDRSN REYAV        
Sbjct: 42   NSEQTLKTQLSHTPSVRKKGVKDFEFGKTLGEGSYSTVVAARDRSNNREYAVKILDKKHI 101

Query: 178  XXXXXXXYVNIEKNTLNKMNHPGIVRLYFTFQDTDSLYFVLDHAKNGELLTFIKKLGSFD 357
                   YVNIEKNTLNKMNHPGIVRLY+TFQD DSLYFVLDHAKNGELLTFIKKLGSFD
Sbjct: 102  IKEKKVKYVNIEKNTLNKMNHPGIVRLYYTFQDPDSLYFVLDHAKNGELLTFIKKLGSFD 161

Query: 358  LNCTQYYAAQILSAIEYMHSQGVIHRDLKPENILLDDKMHVKVTDFGTAKILEQNADGEE 537
            ++CT++YA+QILSAIEYMHSQGVIHRDLKPENILLD+KMHVKVTDFGTAKILEQNA+GEE
Sbjct: 162  MDCTKFYASQILSAIEYMHSQGVIHRDLKPENILLDEKMHVKVTDFGTAKILEQNAEGEE 221

Query: 538  DDRANSFVGTAEYVSPELLKEKAACKSSDFWALGCIIYQLIAGRPPFKGANEYRTFQKIV 717
            DDRANSFVGTAEYVSPELLKEKAACKSSDFWALGCIIYQLIAGRPPFKGANEYRTFQKIV
Sbjct: 222  DDRANSFVGTAEYVSPELLKEKAACKSSDFWALGCIIYQLIAGRPPFKGANEYRTFQKIV 281

Query: 718  NLEYSFPDGFPPVARDLVQKLLVLNPSERLGSGGKAGVERLKAHPFFQGIDWDILWQQPA 897
            NLEYSFPDGFPPVARDLVQKLLVLNPSERLGSGGKAGVERLKAHPFFQGIDWD LWQQPA
Sbjct: 282  NLEYSFPDGFPPVARDLVQKLLVLNPSERLGSGGKAGVERLKAHPFFQGIDWDTLWQQPA 341

Query: 898  PRLLPYLPPNPQHNDPEFRTPTSAYLRKLSDHSGEANSSPIATGLKHNDPFRLESWAGGD 1077
            P LLPYLPPNP+HNDPEFRTPT+AYL KLSD+S E N SPIATGL+ NDPFRLESWAGGD
Sbjct: 342  PNLLPYLPPNPKHNDPEFRTPTNAYLPKLSDNS-EVNGSPIATGLRQNDPFRLESWAGGD 400

Query: 1078 DSPDKVDPEKVKKLEEQKRTSSQWIPFILKSELIIKTGPINKRKGFFSKKRTLILTDFPR 1257
            DS DKVDPEKVKKLEEQKRTS+QW+PFILKSELIIKTGPINKRKGFFSKKRTLILTDFPR
Sbjct: 401  DSSDKVDPEKVKKLEEQKRTSAQWLPFILKSELIIKTGPINKRKGFFSKKRTLILTDFPR 460

Query: 1258 LIYVDQEKNSQKGEIYWSSRMVVELKNKRNFFIHTPRKTYYFEDPNNAAHEWVTKINELL 1437
            LIYVDQEKNSQKGEIYWSSRMVVELKNKRNFFIHTPRKTYYFEDPNNAAHEWVTKINELL
Sbjct: 461  LIYVDQEKNSQKGEIYWSSRMVVELKNKRNFFIHTPRKTYYFEDPNNAAHEWVTKINELL 520

Query: 1438 VANYGEMF 1461
            VANYGEMF
Sbjct: 521  VANYGEMF 528


>gb|PKC07109.1| Pkinase-domain-containing protein [Rhizophagus irregularis]
 gb|PKC63720.1| Pkinase-domain-containing protein [Rhizophagus irregularis]
          Length = 424

 Score =  692 bits (1785), Expect = 0.0
 Identities = 341/384 (88%), Positives = 355/384 (92%), Gaps = 3/384 (0%)
 Frame = +1

Query: 7    NSQQTLKT---HTPFVRKKGVKDFEFGKTLGEGSYSTVVAARDRSNGREYAVXXXXXXXX 177
            NS+QTLKT   HTP VRKKGVKDFEFGKTLGEGSYSTVVAARDRSN REYAV        
Sbjct: 42   NSEQTLKTQLSHTPSVRKKGVKDFEFGKTLGEGSYSTVVAARDRSNNREYAVKILDKKHI 101

Query: 178  XXXXXXXYVNIEKNTLNKMNHPGIVRLYFTFQDTDSLYFVLDHAKNGELLTFIKKLGSFD 357
                   YVNIEKNTLNKMNHPGIVRLY+TFQD DSLYFVLDHAKNGELLTFIKKLGSFD
Sbjct: 102  IKEKKVKYVNIEKNTLNKMNHPGIVRLYYTFQDPDSLYFVLDHAKNGELLTFIKKLGSFD 161

Query: 358  LNCTQYYAAQILSAIEYMHSQGVIHRDLKPENILLDDKMHVKVTDFGTAKILEQNADGEE 537
            ++CT++YA+QILSAIEYMHSQGVIHRDLKPENILLD+KMHVKVTDFGTAKILEQNA+GEE
Sbjct: 162  MDCTKFYASQILSAIEYMHSQGVIHRDLKPENILLDEKMHVKVTDFGTAKILEQNAEGEE 221

Query: 538  DDRANSFVGTAEYVSPELLKEKAACKSSDFWALGCIIYQLIAGRPPFKGANEYRTFQKIV 717
            DDRANSFVGTAEYVSPELLKEKAACKSSDFWALGCIIYQLIAGRPPFKGANEYRTFQKIV
Sbjct: 222  DDRANSFVGTAEYVSPELLKEKAACKSSDFWALGCIIYQLIAGRPPFKGANEYRTFQKIV 281

Query: 718  NLEYSFPDGFPPVARDLVQKLLVLNPSERLGSGGKAGVERLKAHPFFQGIDWDILWQQPA 897
            NLEYSFPDGFPPVARDLVQKLLVLNPSERLGSGGKAGVERLKAHPFFQGIDWD LWQQPA
Sbjct: 282  NLEYSFPDGFPPVARDLVQKLLVLNPSERLGSGGKAGVERLKAHPFFQGIDWDTLWQQPA 341

Query: 898  PRLLPYLPPNPQHNDPEFRTPTSAYLRKLSDHSGEANSSPIATGLKHNDPFRLESWAGGD 1077
            P LLPYLPPNP+HNDPEFRTPT+AYL KLSD+S E N SPIATGL+ NDPFRLESWAGGD
Sbjct: 342  PNLLPYLPPNPKHNDPEFRTPTNAYLPKLSDNS-EVNGSPIATGLRQNDPFRLESWAGGD 400

Query: 1078 DSPDKVDPEKVKKLEEQKRTSSQW 1149
            DS DKVDPEKVKKLEEQKRTS+QW
Sbjct: 401  DSSDKVDPEKVKKLEEQKRTSAQW 424


>gb|ORY01027.1| kinase-like protein [Basidiobolus meristosporus CBS 931.73]
          Length = 514

 Score =  543 bits (1399), Expect = 0.0
 Identities = 266/472 (56%), Positives = 350/472 (74%), Gaps = 4/472 (0%)
 Frame = +1

Query: 46   RKKGVKDFEFGKTLGEGSYSTVVAARDRSNGREYAVXXXXXXXXXXXXXXXYVNIEKNTL 225
            RK+  KDF FG+ LGEGSYSTV +A + + GRE+AV               YV IEK+TL
Sbjct: 56   RKRTPKDFSFGRVLGEGSYSTVYSAMEYNTGREFAVKVLDKRHIIKEKKVKYVTIEKSTL 115

Query: 226  NKMNHPGIVRLYFTFQDTDSLYFVLDHAKNGELLTFIKKLGSFDLNCTQYYAAQILSAIE 405
            +K++HP IVRL+FTFQD  SLY+VLD+A+NGELL++I+KLGSFD  CT++YAA+I++A+E
Sbjct: 116  SKLHHPFIVRLHFTFQDNSSLYYVLDYAQNGELLSYIRKLGSFDEKCTRFYAAEIITAME 175

Query: 406  YMHSQGVIHRDLKPENILLDDKMHVKVTDFGTAKILEQNADGEEDD----RANSFVGTAE 573
            Y+HSQG+IHRDLKPENILLD KMH+K+TDFGTAK+++   +   D+    RA+SFVGTAE
Sbjct: 176  YIHSQGIIHRDLKPENILLDHKMHIKLTDFGTAKMVDDPPEAASDELMEGRASSFVGTAE 235

Query: 574  YVSPELLKEKAACKSSDFWALGCIIYQLIAGRPPFKGANEYRTFQKIVNLEYSFPDGFPP 753
            YVSPELL +K   KS+DFWALGCI+YQL+AGRPPFKGANEY+TFQKI+ LEYSFP GFP 
Sbjct: 236  YVSPELLTDKEVSKSADFWALGCILYQLLAGRPPFKGANEYQTFQKIIKLEYSFPVGFPK 295

Query: 754  VARDLVQKLLVLNPSERLGSGGKAGVERLKAHPFFQGIDWDILWQQPAPRLLPYLPPNPQ 933
             A+DLV++LLV +P +RLG     G+++LK HPFF+GIDW+ L +Q AP+L+PYLPPNP+
Sbjct: 296  TAQDLVERLLVADPQQRLGCDSD-GIQKLKKHPFFEGIDWNDLHKQEAPKLVPYLPPNPE 354

Query: 934  HNDPEFRTPTSAYLRKLSDHSGEANSSPIATGLKHNDPFRLESWAGGDDSPDKVDPEKVK 1113
            HN  E R+    Y              P    L   DPF+ E  A  D +    DP++ +
Sbjct: 355  HNAEELRSTEPDY-----------THPPTQPSLTEQDPFQ-EPRASIDQAN---DPDRAQ 399

Query: 1114 KLEEQKRTSSQWIPFILKSELIIKTGPINKRKGFFSKKRTLILTDFPRLIYVDQEKNSQK 1293
            KLE Q++  S+W PF+L+SELI++ G + KR+G FSKKR L+LTDFPRLIY+++EK +Q 
Sbjct: 400  KLEAQRK--SKWSPFLLESELIVRCGKLTKRRGLFSKKRVLLLTDFPRLIYINEEKMTQA 457

Query: 1294 GEIYWSSRMVVELKNKRNFFIHTPRKTYYFEDPNNAAHEWVTKINELLVANY 1449
            GEI WS R++ E KNK++FF+HTP KT+YFEDP   A +WV  I++L+  +Y
Sbjct: 458  GEIAWSKRLLPEYKNKKHFFVHTPNKTHYFEDPTGNAQQWVESISQLMKQSY 509


>ref|XP_004346099.1| PkB kinase [Capsaspora owczarzaki ATCC 30864]
 gb|KJE94855.1| AGC/PDK1 protein kinase [Capsaspora owczarzaki ATCC 30864]
          Length = 602

 Score =  479 bits (1233), Expect = e-160
 Identities = 246/465 (52%), Positives = 317/465 (68%)
 Frame = +1

Query: 43   VRKKGVKDFEFGKTLGEGSYSTVVAARDRSNGREYAVXXXXXXXXXXXXXXXYVNIEKNT 222
            +RK+   DFEFG  LGEGSYSTVV A+++S  R +AV               YVN EK+ 
Sbjct: 140  MRKRAPSDFEFGDVLGEGSYSTVVLAKEKSTSRYFAVKILEKKHIIKEKKVKYVNTEKDV 199

Query: 223  LNKMNHPGIVRLYFTFQDTDSLYFVLDHAKNGELLTFIKKLGSFDLNCTQYYAAQILSAI 402
            LN++NHP  VRL++TFQD + LYFV+  A NGELLT IKKLGSFD  C Q+YAA+I+ A+
Sbjct: 200  LNRVNHPFFVRLFYTFQDVERLYFVISFAANGELLTTIKKLGSFDERCAQFYAAEIVVAL 259

Query: 403  EYMHSQGVIHRDLKPENILLDDKMHVKVTDFGTAKILEQNADGEEDDRANSFVGTAEYVS 582
            EY+H+ GVIHRDLKPENILLD  MH+K+TDFG+A ++ Q  D E D RANSFVGTAEYVS
Sbjct: 260  EYLHNLGVIHRDLKPENILLDTDMHIKITDFGSAYLIGQ--DAETDVRANSFVGTAEYVS 317

Query: 583  PELLKEKAACKSSDFWALGCIIYQLIAGRPPFKGANEYRTFQKIVNLEYSFPDGFPPVAR 762
            PELL EK A K+SD+WALGCIIYQ++AGRPPF+  NEY+TFQKI  L+YS P+GFPP AR
Sbjct: 318  PELLTEKIASKASDWWALGCIIYQMLAGRPPFRAGNEYQTFQKITKLDYSIPNGFPPAAR 377

Query: 763  DLVQKLLVLNPSERLGSGGKAGVERLKAHPFFQGIDWDILWQQPAPRLLPYLPPNPQHND 942
            DLV+KLLVL+ S+RLGS    GV  +K+HPFF+G++W+ L  Q  P L+PYLPP  +++ 
Sbjct: 378  DLVEKLLVLDSSKRLGSDSAGGVNAIKSHPFFRGLEWNSLHMQQPPALVPYLPPISRNSV 437

Query: 943  PEFRTPTSAYLRKLSDHSGEANSSPIATGLKHNDPFRLESWAGGDDSPDKVDPEKVKKLE 1122
            P         L  +     +  ++P+ + L   + F L        +P++        L 
Sbjct: 438  P---------LHSVIRDDDDEEAAPLQSAL---ESFTL-------TAPERAGMRSQLLLR 478

Query: 1123 EQKRTSSQWIPFILKSELIIKTGPINKRKGFFSKKRTLILTDFPRLIYVDQEKNSQKGEI 1302
            + +   SQW  F+   ELIIKTG I+KRKG FSK+R L+LTD PR +Y+D +K   KGEI
Sbjct: 479  QAQ--ESQWHRFVQVDELIIKTGIIHKRKGLFSKRRQLVLTDKPRCLYIDVDKMEIKGEI 536

Query: 1303 YWSSRMVVELKNKRNFFIHTPRKTYYFEDPNNAAHEWVTKINELL 1437
             WS+ M  E+KNK+ FFIHTP +TYY ED +  A+ W  + N LL
Sbjct: 537  PWSTEMRFEVKNKKTFFIHTPNRTYYLEDLSADAYGWCEQFNALL 581


>ref|XP_020024613.1| 3-phosphoinositide-dependent protein kinase 1 isoform X2 [Castor
            canadensis]
          Length = 532

 Score =  453 bits (1166), Expect = e-151
 Identities = 233/492 (47%), Positives = 319/492 (64%), Gaps = 9/492 (1%)
 Frame = +1

Query: 1    SDNSQQTLKTHTPFVRKKGVKDFEFGKTLGEGSYSTVVAARDRSNGREYAVXXXXXXXXX 180
            S N  Q      P  RKK  +DF+FGK LGEGS+STVV AR+ +  REYA+         
Sbjct: 35   STNPLQHAAQPPPQPRKKRPEDFKFGKILGEGSFSTVVLARELATSREYAIKILEKRHII 94

Query: 181  XXXXXXYVNIEKNTLNKMNHPGIVRLYFTFQDTDSLYFVLDHAKNGELLTFIKKLGSFDL 360
                  YV  E++ +++++HP  V+LYFTFQD + LYF L +AKNGELL +I+K+GSFD 
Sbjct: 95   KENKVPYVTRERDVMSRLDHPFFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDE 154

Query: 361  NCTQYYAAQILSAIEYMHSQGVIHRDLKPENILLDDKMHVKVTDFGTAKILEQNADGEED 540
             CT++Y A+I+SA+EY+H +G+IHRDLKPENILL++ MH+++TDFGTAK+L   +   + 
Sbjct: 155  TCTRFYTAEIVSALEYLHGKGIIHRDLKPENILLNEDMHIQITDFGTAKVLSPES---KQ 211

Query: 541  DRANSFVGTAEYVSPELLKEKAACKSSDFWALGCIIYQLIAGRPPFKGANEYRTFQKIVN 720
             RANSFVGTA+YVSPELL EK+ACKSSD WALGCIIYQL+AG PPF+  NEY  FQKI+ 
Sbjct: 212  ARANSFVGTAQYVSPELLTEKSACKSSDLWALGCIIYQLVAGLPPFRAGNEYLIFQKIIK 271

Query: 721  LEYSFPDGFPPVARDLVQKLLVLNPSERLGSGGKAGVERLKAHPFFQGIDWDILWQQPAP 900
            LEY FP+ F P ARDLV+KLLVL+ ++RLG     G E LKAHPFF+ I W+ L QQ  P
Sbjct: 272  LEYDFPEKFFPKARDLVEKLLVLDATKRLGCEEMEGYEPLKAHPFFESIMWENLHQQTPP 331

Query: 901  RLLPYLPPNPQHNDPEFRTPTSAYLR----KLSDHSGEANSSPIATGLKHNDPFRLESWA 1068
            +L  YLP   + ++  +    +   +    ++S  S   + S + TGL H     +E + 
Sbjct: 332  KLTAYLPAMSEDDEDCYGNYDNLLSQFGCMQVSSSSSSHSLSAVDTGLPHRSGSNIEQYI 391

Query: 1069 GGDDSPD-----KVDPEKVKKLEEQKRTSSQWIPFILKSELIIKTGPINKRKGFFSKKRT 1233
               D+       +   ++ + L E++   + W  F+ ++ LI+K GP++KRKG F+++R 
Sbjct: 392  HDLDTNSFELDLQFSEDEKRLLLEKQAGGNPWHQFV-ENNLILKMGPVDKRKGLFARRRQ 450

Query: 1234 LILTDFPRLIYVDQEKNSQKGEIYWSSRMVVELKNKRNFFIHTPRKTYYFEDPNNAAHEW 1413
            L+LT+ P L YVD      KGEI WS  +  E KN + FF+HTP +TYY  DP+  AH+W
Sbjct: 451  LLLTEGPHLYYVDPVNKVLKGEIPWSQELRPEAKNFKTFFVHTPNRTYYLMDPSGNAHKW 510

Query: 1414 VTKINELLVANY 1449
              KI E+    Y
Sbjct: 511  CRKIQEVWRQRY 522


>ref|XP_008843764.1| PREDICTED: 3-phosphoinositide-dependent protein kinase 1 isoform X2
            [Nannospalax galili]
          Length = 531

 Score =  452 bits (1164), Expect = e-151
 Identities = 233/492 (47%), Positives = 318/492 (64%), Gaps = 9/492 (1%)
 Frame = +1

Query: 1    SDNSQQTLKTHTPFVRKKGVKDFEFGKTLGEGSYSTVVAARDRSNGREYAVXXXXXXXXX 180
            S N  Q      P  RKK  +DF+FGK LGEGS+STVV AR+ +  REYA+         
Sbjct: 35   STNPLQHPAQPPPQPRKKRPEDFKFGKILGEGSFSTVVLARELTTSREYAIKILEKRHII 94

Query: 181  XXXXXXYVNIEKNTLNKMNHPGIVRLYFTFQDTDSLYFVLDHAKNGELLTFIKKLGSFDL 360
                  YV  E++ +++++HP  V+LYFTFQD + LYF L +AKNGELL +I+K+GSFD 
Sbjct: 95   KENKVPYVTRERDVMSRLDHPFFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDE 154

Query: 361  NCTQYYAAQILSAIEYMHSQGVIHRDLKPENILLDDKMHVKVTDFGTAKILEQNADGEED 540
             CT++Y A+I+SA+EY+H +G+IHRDLKPENILL++ MH+++TDFGTAK+L   +   + 
Sbjct: 155  TCTRFYTAEIVSALEYLHGKGIIHRDLKPENILLNEDMHIQITDFGTAKVLSPES---KQ 211

Query: 541  DRANSFVGTAEYVSPELLKEKAACKSSDFWALGCIIYQLIAGRPPFKGANEYRTFQKIVN 720
             RANSFVGTA+YVSPELL EK+ACKSSD WALGCIIYQL+AG PPF+  NEY  FQKI+ 
Sbjct: 212  ARANSFVGTAQYVSPELLTEKSACKSSDLWALGCIIYQLVAGLPPFRAGNEYLIFQKIIK 271

Query: 721  LEYSFPDGFPPVARDLVQKLLVLNPSERLGSGGKAGVERLKAHPFFQGIDWDILWQQPAP 900
            LEY FP+ F P ARDLV+KLLVL+ ++RLG     G E LKAHPFF+ I W+ L QQ  P
Sbjct: 272  LEYDFPEKFFPKARDLVEKLLVLDATKRLGCEEMEGYEPLKAHPFFESITWENLHQQTPP 331

Query: 901  RLLPYLPPNPQHNDPEFRTPTSAYLR----KLSDHSGEANSSPIATGLKHNDPFRLESWA 1068
            +L  YLP   + ++  +    +   +    ++S  S   + S +  GL H     +E + 
Sbjct: 332  KLTAYLPAMSEDDEDCYGNYDNLLSQFGCMQVSSSSSSHSLSAVDAGLPHRSGSNIEQYI 391

Query: 1069 GGDDSPD-----KVDPEKVKKLEEQKRTSSQWIPFILKSELIIKTGPINKRKGFFSKKRT 1233
               D+       +   E+ + L E++   + W  F+ ++ LI+K GP++KRKG F+++R 
Sbjct: 392  HDLDTNSFELDLQFSEEEKRLLLEKQAGGNPWHQFV-ENNLILKMGPVDKRKGLFARRRQ 450

Query: 1234 LILTDFPRLIYVDQEKNSQKGEIYWSSRMVVELKNKRNFFIHTPRKTYYFEDPNNAAHEW 1413
            L+LT+ P L YVD      KGEI WS  +  E KN + FF+HTP +TYY  DP+  AH+W
Sbjct: 451  LLLTEGPHLYYVDPVNKVLKGEIPWSQELRPEAKNFKTFFVHTPNRTYYLMDPSGNAHKW 510

Query: 1414 VTKINELLVANY 1449
              KI E+    Y
Sbjct: 511  CRKIQEVWRQRY 522


>ref|XP_020024612.1| 3-phosphoinositide-dependent protein kinase 1 isoform X1 [Castor
            canadensis]
          Length = 559

 Score =  453 bits (1166), Expect = e-150
 Identities = 233/492 (47%), Positives = 319/492 (64%), Gaps = 9/492 (1%)
 Frame = +1

Query: 1    SDNSQQTLKTHTPFVRKKGVKDFEFGKTLGEGSYSTVVAARDRSNGREYAVXXXXXXXXX 180
            S N  Q      P  RKK  +DF+FGK LGEGS+STVV AR+ +  REYA+         
Sbjct: 62   STNPLQHAAQPPPQPRKKRPEDFKFGKILGEGSFSTVVLARELATSREYAIKILEKRHII 121

Query: 181  XXXXXXYVNIEKNTLNKMNHPGIVRLYFTFQDTDSLYFVLDHAKNGELLTFIKKLGSFDL 360
                  YV  E++ +++++HP  V+LYFTFQD + LYF L +AKNGELL +I+K+GSFD 
Sbjct: 122  KENKVPYVTRERDVMSRLDHPFFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDE 181

Query: 361  NCTQYYAAQILSAIEYMHSQGVIHRDLKPENILLDDKMHVKVTDFGTAKILEQNADGEED 540
             CT++Y A+I+SA+EY+H +G+IHRDLKPENILL++ MH+++TDFGTAK+L   +   + 
Sbjct: 182  TCTRFYTAEIVSALEYLHGKGIIHRDLKPENILLNEDMHIQITDFGTAKVLSPES---KQ 238

Query: 541  DRANSFVGTAEYVSPELLKEKAACKSSDFWALGCIIYQLIAGRPPFKGANEYRTFQKIVN 720
             RANSFVGTA+YVSPELL EK+ACKSSD WALGCIIYQL+AG PPF+  NEY  FQKI+ 
Sbjct: 239  ARANSFVGTAQYVSPELLTEKSACKSSDLWALGCIIYQLVAGLPPFRAGNEYLIFQKIIK 298

Query: 721  LEYSFPDGFPPVARDLVQKLLVLNPSERLGSGGKAGVERLKAHPFFQGIDWDILWQQPAP 900
            LEY FP+ F P ARDLV+KLLVL+ ++RLG     G E LKAHPFF+ I W+ L QQ  P
Sbjct: 299  LEYDFPEKFFPKARDLVEKLLVLDATKRLGCEEMEGYEPLKAHPFFESIMWENLHQQTPP 358

Query: 901  RLLPYLPPNPQHNDPEFRTPTSAYLR----KLSDHSGEANSSPIATGLKHNDPFRLESWA 1068
            +L  YLP   + ++  +    +   +    ++S  S   + S + TGL H     +E + 
Sbjct: 359  KLTAYLPAMSEDDEDCYGNYDNLLSQFGCMQVSSSSSSHSLSAVDTGLPHRSGSNIEQYI 418

Query: 1069 GGDDSPD-----KVDPEKVKKLEEQKRTSSQWIPFILKSELIIKTGPINKRKGFFSKKRT 1233
               D+       +   ++ + L E++   + W  F+ ++ LI+K GP++KRKG F+++R 
Sbjct: 419  HDLDTNSFELDLQFSEDEKRLLLEKQAGGNPWHQFV-ENNLILKMGPVDKRKGLFARRRQ 477

Query: 1234 LILTDFPRLIYVDQEKNSQKGEIYWSSRMVVELKNKRNFFIHTPRKTYYFEDPNNAAHEW 1413
            L+LT+ P L YVD      KGEI WS  +  E KN + FF+HTP +TYY  DP+  AH+W
Sbjct: 478  LLLTEGPHLYYVDPVNKVLKGEIPWSQELRPEAKNFKTFFVHTPNRTYYLMDPSGNAHKW 537

Query: 1414 VTKINELLVANY 1449
              KI E+    Y
Sbjct: 538  CRKIQEVWRQRY 549


>ref|XP_008843756.1| PREDICTED: 3-phosphoinositide-dependent protein kinase 1 isoform X1
            [Nannospalax galili]
          Length = 558

 Score =  452 bits (1164), Expect = e-150
 Identities = 233/492 (47%), Positives = 318/492 (64%), Gaps = 9/492 (1%)
 Frame = +1

Query: 1    SDNSQQTLKTHTPFVRKKGVKDFEFGKTLGEGSYSTVVAARDRSNGREYAVXXXXXXXXX 180
            S N  Q      P  RKK  +DF+FGK LGEGS+STVV AR+ +  REYA+         
Sbjct: 62   STNPLQHPAQPPPQPRKKRPEDFKFGKILGEGSFSTVVLARELTTSREYAIKILEKRHII 121

Query: 181  XXXXXXYVNIEKNTLNKMNHPGIVRLYFTFQDTDSLYFVLDHAKNGELLTFIKKLGSFDL 360
                  YV  E++ +++++HP  V+LYFTFQD + LYF L +AKNGELL +I+K+GSFD 
Sbjct: 122  KENKVPYVTRERDVMSRLDHPFFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDE 181

Query: 361  NCTQYYAAQILSAIEYMHSQGVIHRDLKPENILLDDKMHVKVTDFGTAKILEQNADGEED 540
             CT++Y A+I+SA+EY+H +G+IHRDLKPENILL++ MH+++TDFGTAK+L   +   + 
Sbjct: 182  TCTRFYTAEIVSALEYLHGKGIIHRDLKPENILLNEDMHIQITDFGTAKVLSPES---KQ 238

Query: 541  DRANSFVGTAEYVSPELLKEKAACKSSDFWALGCIIYQLIAGRPPFKGANEYRTFQKIVN 720
             RANSFVGTA+YVSPELL EK+ACKSSD WALGCIIYQL+AG PPF+  NEY  FQKI+ 
Sbjct: 239  ARANSFVGTAQYVSPELLTEKSACKSSDLWALGCIIYQLVAGLPPFRAGNEYLIFQKIIK 298

Query: 721  LEYSFPDGFPPVARDLVQKLLVLNPSERLGSGGKAGVERLKAHPFFQGIDWDILWQQPAP 900
            LEY FP+ F P ARDLV+KLLVL+ ++RLG     G E LKAHPFF+ I W+ L QQ  P
Sbjct: 299  LEYDFPEKFFPKARDLVEKLLVLDATKRLGCEEMEGYEPLKAHPFFESITWENLHQQTPP 358

Query: 901  RLLPYLPPNPQHNDPEFRTPTSAYLR----KLSDHSGEANSSPIATGLKHNDPFRLESWA 1068
            +L  YLP   + ++  +    +   +    ++S  S   + S +  GL H     +E + 
Sbjct: 359  KLTAYLPAMSEDDEDCYGNYDNLLSQFGCMQVSSSSSSHSLSAVDAGLPHRSGSNIEQYI 418

Query: 1069 GGDDSPD-----KVDPEKVKKLEEQKRTSSQWIPFILKSELIIKTGPINKRKGFFSKKRT 1233
               D+       +   E+ + L E++   + W  F+ ++ LI+K GP++KRKG F+++R 
Sbjct: 419  HDLDTNSFELDLQFSEEEKRLLLEKQAGGNPWHQFV-ENNLILKMGPVDKRKGLFARRRQ 477

Query: 1234 LILTDFPRLIYVDQEKNSQKGEIYWSSRMVVELKNKRNFFIHTPRKTYYFEDPNNAAHEW 1413
            L+LT+ P L YVD      KGEI WS  +  E KN + FF+HTP +TYY  DP+  AH+W
Sbjct: 478  LLLTEGPHLYYVDPVNKVLKGEIPWSQELRPEAKNFKTFFVHTPNRTYYLMDPSGNAHKW 537

Query: 1414 VTKINELLVANY 1449
              KI E+    Y
Sbjct: 538  CRKIQEVWRQRY 549


>ref|XP_004652256.1| PREDICTED: 3-phosphoinositide-dependent protein kinase 1 isoform X1
            [Jaculus jaculus]
          Length = 532

 Score =  450 bits (1157), Expect = e-149
 Identities = 228/480 (47%), Positives = 315/480 (65%), Gaps = 9/480 (1%)
 Frame = +1

Query: 37   PFVRKKGVKDFEFGKTLGEGSYSTVVAARDRSNGREYAVXXXXXXXXXXXXXXXYVNIEK 216
            P  RKK  +DF+FGK LGEGS+STVV AR+ +  REYA+               YV  E+
Sbjct: 48   PQPRKKRPEDFKFGKILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRER 107

Query: 217  NTLNKMNHPGIVRLYFTFQDTDSLYFVLDHAKNGELLTFIKKLGSFDLNCTQYYAAQILS 396
            + +++++HP  V+LYFTFQD + LYF L +AKNGELL +I+K+GSFD  CT++Y A+I+S
Sbjct: 108  DVMSRLDHPFFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVS 167

Query: 397  AIEYMHSQGVIHRDLKPENILLDDKMHVKVTDFGTAKILEQNADGEEDDRANSFVGTAEY 576
            A+EY+H +G+IHRDLKPENILL++ MH+++TDFGTAK+L   +   +  RANSFVGTA+Y
Sbjct: 168  ALEYLHGKGIIHRDLKPENILLNEDMHIQITDFGTAKVLSPES---KQARANSFVGTAQY 224

Query: 577  VSPELLKEKAACKSSDFWALGCIIYQLIAGRPPFKGANEYRTFQKIVNLEYSFPDGFPPV 756
            VSPELL EK+ACKSSD WALGCIIYQL+AG PPF+  NEY  FQKI+ LEY FP+ F P 
Sbjct: 225  VSPELLTEKSACKSSDLWALGCIIYQLVAGLPPFRAGNEYLIFQKIIKLEYDFPEKFFPK 284

Query: 757  ARDLVQKLLVLNPSERLGSGGKAGVERLKAHPFFQGIDWDILWQQPAPRLLPYLPPNPQH 936
            ARDLV+KLLVL+ ++RLG     G E LKAHPFF+ I W+ L QQ  P+L  YLP   + 
Sbjct: 285  ARDLVEKLLVLDATKRLGCEEMEGYEPLKAHPFFESITWENLHQQTPPKLTAYLPAMSED 344

Query: 937  NDPEFRTPTSAYLR----KLSDHSGEANSSPIATGLKHNDPFRLESWAGGDDSPD----- 1089
            ++  +    +   +    ++S  S   + S +   L H     +E +    D+       
Sbjct: 345  DEDCYGNYDNLLSQFGCMQVSSSSSSHSLSTVDASLPHRSGSNIEQYIHDLDTNSFELDL 404

Query: 1090 KVDPEKVKKLEEQKRTSSQWIPFILKSELIIKTGPINKRKGFFSKKRTLILTDFPRLIYV 1269
            +   ++ + L E++ + + W  F+ ++ LI+K GP++KRKG F+++R L+LT+ P L YV
Sbjct: 405  QFSEDEKRLLLEKQASGNPWHQFV-ENNLILKMGPVDKRKGLFARRRQLLLTEGPHLYYV 463

Query: 1270 DQEKNSQKGEIYWSSRMVVELKNKRNFFIHTPRKTYYFEDPNNAAHEWVTKINELLVANY 1449
            D      KGEI WS  +  E KN + FF+HTP +TYY  DP+  AH+W  KI E+    Y
Sbjct: 464  DPVNKVLKGEIPWSQELRPEAKNFKTFFVHTPNRTYYLMDPSGNAHKWCRKIQEVWRQRY 523


>ref|XP_012867072.1| PREDICTED: 3-phosphoinositide-dependent protein kinase 1 isoform X1
            [Dipodomys ordii]
          Length = 533

 Score =  450 bits (1157), Expect = e-149
 Identities = 231/482 (47%), Positives = 313/482 (64%), Gaps = 11/482 (2%)
 Frame = +1

Query: 37   PFVRKKGVKDFEFGKTLGEGSYSTVVAARDRSNGREYAVXXXXXXXXXXXXXXXYVNIEK 216
            P  RKK  +DF+FGK LGEGS+STVV AR+ +  REYA+               YV  E+
Sbjct: 47   PQPRKKRPEDFKFGKILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRER 106

Query: 217  NTLNKMNHPGIVRLYFTFQDTDSLYFVLDHAKNGELLTFIKKLGSFDLNCTQYYAAQILS 396
            + +++++HP  V+LYFTFQD + LYF L +AKNGELL +I+K+GSFD  CT++Y A+I+S
Sbjct: 107  DVMSRLDHPFFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVS 166

Query: 397  AIEYMHSQGVIHRDLKPENILLDDKMHVKVTDFGTAKILEQNADGEEDDRANSFVGTAEY 576
            A+EY+H +G+IHRDLKPENILL++ MH+++TDFGTAK+L   +   +  RANSFVGTA+Y
Sbjct: 167  ALEYLHGKGIIHRDLKPENILLNEDMHIQITDFGTAKVLSPES---KQARANSFVGTAQY 223

Query: 577  VSPELLKEKAACKSSDFWALGCIIYQLIAGRPPFKGANEYRTFQKIVNLEYSFPDGFPPV 756
            VSPELL EK+ACKSSD WALGCIIYQL+AG PPF+  NEY  FQKI+ LEY FP+ F P 
Sbjct: 224  VSPELLTEKSACKSSDLWALGCIIYQLVAGLPPFRAGNEYLIFQKIIKLEYDFPEKFFPK 283

Query: 757  ARDLVQKLLVLNPSERLGSGGKAGVERLKAHPFFQGIDWDILWQQPAPRLLPYLPPNPQH 936
            ARDLV+KLLVL+ ++RLG     G E LKAHPFF+ I W  L QQ  P+L  YLP   + 
Sbjct: 284  ARDLVEKLLVLDATKRLGCEEMEGYEPLKAHPFFESILWANLHQQTPPKLTAYLPAMSED 343

Query: 937  NDPEFRTPTSAYLR------KLSDHSGEANSSPIATGLKHNDPFRLESWAGGDDSPD--- 1089
            ++  +    +   +        S  S   + S + T L H     +E +  G D+     
Sbjct: 344  DEDCYGNYDNLLSQFGCMQVSSSSSSSSHSLSAVDTSLPHRSGSNIEQYIHGLDTNSFEL 403

Query: 1090 --KVDPEKVKKLEEQKRTSSQWIPFILKSELIIKTGPINKRKGFFSKKRTLILTDFPRLI 1263
              +   ++ K L E++   + W  F+ ++ LI+K GP++KRKG F+++R L+LT+ P L 
Sbjct: 404  DLQFSEDEKKLLLEKQACGNPWHQFV-ENNLILKMGPVDKRKGLFARRRQLLLTEGPHLY 462

Query: 1264 YVDQEKNSQKGEIYWSSRMVVELKNKRNFFIHTPRKTYYFEDPNNAAHEWVTKINELLVA 1443
            YVD      KGEI WS  +  E KN + FF+HTP +TYY  DP+  AH+W  KI E+   
Sbjct: 463  YVDPVNKVLKGEIPWSQELRPEAKNFKTFFVHTPNRTYYLMDPSGNAHKWCRKIQEVWRQ 522

Query: 1444 NY 1449
             Y
Sbjct: 523  RY 524


>ref|XP_003478169.2| 3-phosphoinositide-dependent protein kinase 1 [Cavia porcellus]
          Length = 531

 Score =  449 bits (1156), Expect = e-149
 Identities = 231/492 (46%), Positives = 318/492 (64%), Gaps = 9/492 (1%)
 Frame = +1

Query: 1    SDNSQQTLKTHTPFVRKKGVKDFEFGKTLGEGSYSTVVAARDRSNGREYAVXXXXXXXXX 180
            S N+ Q      P  RKK  +DF+FGK LGEGS+STVV AR+ +  REYA+         
Sbjct: 35   SANNLQHAAQPLPQPRKKRPEDFKFGKILGEGSFSTVVLARELATSREYAIKILEKRHII 94

Query: 181  XXXXXXYVNIEKNTLNKMNHPGIVRLYFTFQDTDSLYFVLDHAKNGELLTFIKKLGSFDL 360
                  YV  E++ +++++HP  V+LYFTFQD + LYF L +AKNGELL +I+K+GSFD 
Sbjct: 95   KENKVPYVTRERDVMSRLDHPFFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDE 154

Query: 361  NCTQYYAAQILSAIEYMHSQGVIHRDLKPENILLDDKMHVKVTDFGTAKILEQNADGEED 540
             CT++Y A+I+SA+EY+H +G+IHRDLKPENILL++ MH+++TDFGTAK+L   +   + 
Sbjct: 155  TCTRFYTAEIVSALEYLHGKGIIHRDLKPENILLNEDMHIQITDFGTAKVLSPES---KQ 211

Query: 541  DRANSFVGTAEYVSPELLKEKAACKSSDFWALGCIIYQLIAGRPPFKGANEYRTFQKIVN 720
             RANSFVGTA+YVSPELL EK+ACKSSD WALGCIIYQL+AG PPF+  NEY  FQKI+ 
Sbjct: 212  ARANSFVGTAQYVSPELLTEKSACKSSDLWALGCIIYQLVAGLPPFRAGNEYLIFQKIIK 271

Query: 721  LEYSFPDGFPPVARDLVQKLLVLNPSERLGSGGKAGVERLKAHPFFQGIDWDILWQQPAP 900
            LEY FP+ F P ARDLV+KLLVL+ ++RLG     G E LKAH FF+ I W+ L QQ  P
Sbjct: 272  LEYDFPEKFFPKARDLVEKLLVLDSTKRLGCEEMEGYEPLKAHSFFESITWENLHQQTPP 331

Query: 901  RLLPYLPPNPQHNDPEFRTPTSAYLR----KLSDHSGEANSSPIATGLKHNDPFRLESWA 1068
            +L  YLP   + ++  +    +   +    ++S  S   + S +  GL H     +E + 
Sbjct: 332  KLTAYLPAMSEDDEDCYGNYDNLLSQFGCMQVSSSSSSHSLSAVDAGLPHRSGSNIEQYI 391

Query: 1069 GGDDSPD-----KVDPEKVKKLEEQKRTSSQWIPFILKSELIIKTGPINKRKGFFSKKRT 1233
               D+       +   ++ + L E++   + W  F+ ++ LI+K GP++KRKG F+++R 
Sbjct: 392  HDLDTNSFELDLQFSEDEKRLLLEKQAGGNPWHQFV-ENNLILKMGPVDKRKGLFARRRQ 450

Query: 1234 LILTDFPRLIYVDQEKNSQKGEIYWSSRMVVELKNKRNFFIHTPRKTYYFEDPNNAAHEW 1413
            L+LT+ P L YVD      KGEI WS  +  E KN + FF+HTP +TYY  DP+  AH+W
Sbjct: 451  LLLTEGPHLYYVDPVNKVLKGEIPWSQELRPEAKNFKTFFVHTPNRTYYLMDPSGNAHKW 510

Query: 1414 VTKINELLVANY 1449
              KI E+    Y
Sbjct: 511  CRKIQEVWRQRY 522


>ref|XP_015346357.1| PREDICTED: 3-phosphoinositide-dependent protein kinase 1 [Marmota
            marmota marmota]
          Length = 530

 Score =  449 bits (1155), Expect = e-149
 Identities = 229/480 (47%), Positives = 314/480 (65%), Gaps = 9/480 (1%)
 Frame = +1

Query: 37   PFVRKKGVKDFEFGKTLGEGSYSTVVAARDRSNGREYAVXXXXXXXXXXXXXXXYVNIEK 216
            P  RKK  +DF+FGK LGEGS+STVV AR+ +  REYA+               YV  E+
Sbjct: 46   PQPRKKRPEDFKFGKILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRER 105

Query: 217  NTLNKMNHPGIVRLYFTFQDTDSLYFVLDHAKNGELLTFIKKLGSFDLNCTQYYAAQILS 396
            + +++++HP  V+LYFTFQD + LYF L +AKNGELL +I+K+GSFD  CT++Y A+I+S
Sbjct: 106  DVMSRLDHPFFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVS 165

Query: 397  AIEYMHSQGVIHRDLKPENILLDDKMHVKVTDFGTAKILEQNADGEEDDRANSFVGTAEY 576
            A+EY+H +G+IHRDLKPENILL++ MH+++TDFGTAK+L   +   +  RANSFVGTA+Y
Sbjct: 166  ALEYLHGKGIIHRDLKPENILLNEDMHIQITDFGTAKVLTPES---KQARANSFVGTAQY 222

Query: 577  VSPELLKEKAACKSSDFWALGCIIYQLIAGRPPFKGANEYRTFQKIVNLEYSFPDGFPPV 756
            VSPELL EK+ACKSSD WALGCIIYQL+AG PPF+  NEY  FQKI+ LEY FP+ F P 
Sbjct: 223  VSPELLTEKSACKSSDLWALGCIIYQLVAGLPPFRAGNEYLIFQKIIKLEYDFPEKFFPK 282

Query: 757  ARDLVQKLLVLNPSERLGSGGKAGVERLKAHPFFQGIDWDILWQQPAPRLLPYLPPNPQH 936
            ARDLV+KLLVL+ ++RLG     G E LKAHPFF+ I W+ L QQ  P+L  YLP   + 
Sbjct: 283  ARDLVEKLLVLDATKRLGCEEMEGYEPLKAHPFFESITWENLHQQTPPKLTAYLPAMSED 342

Query: 937  NDPEFRTPTSAYLR----KLSDHSGEANSSPIATGLKHNDPFRLESWAGGDDSPD----- 1089
            ++  +    +   +    ++S  S   + S    GL H     +E +    D+       
Sbjct: 343  DEDCYGNYDNLLSQFGCMQVSSSSSSHSLSTADAGLPHRSGSNIEQYIHDLDTNSFELDL 402

Query: 1090 KVDPEKVKKLEEQKRTSSQWIPFILKSELIIKTGPINKRKGFFSKKRTLILTDFPRLIYV 1269
            +   ++ + L E++   + W  F+ ++ LI+K GP++KRKG F+++R L+LT+ P L YV
Sbjct: 403  QFSEDEKRLLLEKQAGGNPWHQFV-ENNLILKMGPVDKRKGLFARRRQLLLTEGPHLYYV 461

Query: 1270 DQEKNSQKGEIYWSSRMVVELKNKRNFFIHTPRKTYYFEDPNNAAHEWVTKINELLVANY 1449
            D      KGEI WS  +  E KN + FF+HTP +TYY  DP+  AH+W  KI E+    Y
Sbjct: 462  DPVNKVLKGEIPWSQELRPEAKNFKTFFVHTPNRTYYLMDPSGNAHKWCRKIQEVWRQRY 521


>ref|XP_005337841.1| 3-phosphoinositide-dependent protein kinase 1 isoform X1 [Ictidomys
            tridecemlineatus]
          Length = 530

 Score =  449 bits (1155), Expect = e-149
 Identities = 229/480 (47%), Positives = 314/480 (65%), Gaps = 9/480 (1%)
 Frame = +1

Query: 37   PFVRKKGVKDFEFGKTLGEGSYSTVVAARDRSNGREYAVXXXXXXXXXXXXXXXYVNIEK 216
            P  RKK  +DF+FGK LGEGS+STVV AR+ +  REYA+               YV  E+
Sbjct: 46   PQPRKKRPEDFKFGKILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRER 105

Query: 217  NTLNKMNHPGIVRLYFTFQDTDSLYFVLDHAKNGELLTFIKKLGSFDLNCTQYYAAQILS 396
            + +++++HP  V+LYFTFQD + LYF L +AKNGELL +I+K+GSFD  CT++Y A+I+S
Sbjct: 106  DVMSRLDHPFFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVS 165

Query: 397  AIEYMHSQGVIHRDLKPENILLDDKMHVKVTDFGTAKILEQNADGEEDDRANSFVGTAEY 576
            A+EY+H +G+IHRDLKPENILL++ MH+++TDFGTAK+L   +   +  RANSFVGTA+Y
Sbjct: 166  ALEYLHGKGIIHRDLKPENILLNEDMHIQITDFGTAKVLTPES---KQARANSFVGTAQY 222

Query: 577  VSPELLKEKAACKSSDFWALGCIIYQLIAGRPPFKGANEYRTFQKIVNLEYSFPDGFPPV 756
            VSPELL EK+ACKSSD WALGCIIYQL+AG PPF+  NEY  FQKI+ LEY FP+ F P 
Sbjct: 223  VSPELLTEKSACKSSDLWALGCIIYQLVAGLPPFRAGNEYLIFQKIIKLEYDFPEKFFPK 282

Query: 757  ARDLVQKLLVLNPSERLGSGGKAGVERLKAHPFFQGIDWDILWQQPAPRLLPYLPPNPQH 936
            ARDLV+KLLVL+ ++RLG     G E LKAHPFF+ I W+ L QQ  P+L  YLP   + 
Sbjct: 283  ARDLVEKLLVLDATKRLGCEEMEGYEPLKAHPFFESITWENLHQQTPPKLTAYLPAMSED 342

Query: 937  NDPEFRTPTSAYLR----KLSDHSGEANSSPIATGLKHNDPFRLESWAGGDDSPD----- 1089
            ++  +    +   +    ++S  S   + S    GL H     +E +    D+       
Sbjct: 343  DEDCYGNYDNLLSQFGCMQVSSSSSSHSLSTADAGLPHRSGSNIEQYIHDLDTNSFELDL 402

Query: 1090 KVDPEKVKKLEEQKRTSSQWIPFILKSELIIKTGPINKRKGFFSKKRTLILTDFPRLIYV 1269
            +   ++ + L E++   + W  F+ ++ LI+K GP++KRKG F+++R L+LT+ P L YV
Sbjct: 403  QFSEDEKRLLLEKQAGGNPWHQFV-ENNLILKMGPVDKRKGLFARRRQLLLTEGPHLYYV 461

Query: 1270 DQEKNSQKGEIYWSSRMVVELKNKRNFFIHTPRKTYYFEDPNNAAHEWVTKINELLVANY 1449
            D      KGEI WS  +  E KN + FF+HTP +TYY  DP+  AH+W  KI E+    Y
Sbjct: 462  DPVNKVLKGEIPWSQELRPEAKNFKTFFVHTPNRTYYLMDPSGNAHKWCRKIQEVWRQRY 521


>ref|XP_010601839.1| PREDICTED: 3-phosphoinositide-dependent protein kinase 1 isoform X1
            [Fukomys damarensis]
 ref|XP_010601840.1| PREDICTED: 3-phosphoinositide-dependent protein kinase 1 isoform X2
            [Fukomys damarensis]
 ref|XP_010601841.1| PREDICTED: 3-phosphoinositide-dependent protein kinase 1 isoform X2
            [Fukomys damarensis]
 gb|KFO23863.1| 3-phosphoinositide-dependent protein kinase 1 [Fukomys damarensis]
          Length = 531

 Score =  449 bits (1155), Expect = e-149
 Identities = 231/492 (46%), Positives = 317/492 (64%), Gaps = 9/492 (1%)
 Frame = +1

Query: 1    SDNSQQTLKTHTPFVRKKGVKDFEFGKTLGEGSYSTVVAARDRSNGREYAVXXXXXXXXX 180
            S N  Q      P  RKK  +DF+FGK LGEGS+STVV AR+ +  REYA+         
Sbjct: 35   SANPLQHAAQPPPQPRKKRPEDFKFGKILGEGSFSTVVLARELATSREYAIKILEKRHII 94

Query: 181  XXXXXXYVNIEKNTLNKMNHPGIVRLYFTFQDTDSLYFVLDHAKNGELLTFIKKLGSFDL 360
                  YV  E++ +++++HP  V+LYFTFQD + LYF L +AKNGELL +I+K+GSFD 
Sbjct: 95   KENKVPYVTRERDVMSRLDHPFFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDE 154

Query: 361  NCTQYYAAQILSAIEYMHSQGVIHRDLKPENILLDDKMHVKVTDFGTAKILEQNADGEED 540
             CT++Y A+I+SA+EY+H +G+IHRDLKPENILL++ MH+++TDFGTAK+L   +   + 
Sbjct: 155  TCTRFYTAEIVSALEYLHGKGIIHRDLKPENILLNEDMHIQITDFGTAKVLSPES---KQ 211

Query: 541  DRANSFVGTAEYVSPELLKEKAACKSSDFWALGCIIYQLIAGRPPFKGANEYRTFQKIVN 720
             RANSFVGTA+YVSPELL EK+ACKSSD WALGCIIYQL+AG PPF+  NEY  FQKI+ 
Sbjct: 212  ARANSFVGTAQYVSPELLTEKSACKSSDLWALGCIIYQLVAGLPPFRAGNEYLIFQKIIK 271

Query: 721  LEYSFPDGFPPVARDLVQKLLVLNPSERLGSGGKAGVERLKAHPFFQGIDWDILWQQPAP 900
            LEY FP+ F P ARDLV+KLLVL+ ++RLG     G E LKAHPFF+ I W+ L QQ  P
Sbjct: 272  LEYDFPEKFFPKARDLVEKLLVLDATKRLGCEEMEGYEPLKAHPFFESITWENLHQQTPP 331

Query: 901  RLLPYLPPNPQHNDPEFRTPTSAYLR----KLSDHSGEANSSPIATGLKHNDPFRLESWA 1068
            +L  YLP   + ++  +    +   +    ++S  S   + S +   L H     +E + 
Sbjct: 332  KLTAYLPAMSEDDEDCYGNYDNLLSQFGCMQVSSSSSSHSLSVVDASLPHRSGSNIEQYI 391

Query: 1069 GGDDSPD-----KVDPEKVKKLEEQKRTSSQWIPFILKSELIIKTGPINKRKGFFSKKRT 1233
               D+       +   ++ + L E++   + W  F+ ++ LI+K GP++KRKG F+++R 
Sbjct: 392  HDLDTNSFELDLQFSEDEKRLLLEKQAGGNPWHQFV-ENNLILKMGPVDKRKGLFARRRQ 450

Query: 1234 LILTDFPRLIYVDQEKNSQKGEIYWSSRMVVELKNKRNFFIHTPRKTYYFEDPNNAAHEW 1413
            L+LT+ P L YVD      KGEI WS  +  E KN + FF+HTP +TYY  DP+  AH+W
Sbjct: 451  LLLTEGPHLYYVDPVNKVLKGEIPWSQELRPEAKNFKTFFVHTPNRTYYLMDPSGNAHKW 510

Query: 1414 VTKINELLVANY 1449
              KI E+    Y
Sbjct: 511  CRKIQEVWRQRY 522


>ref|XP_007528101.1| PREDICTED: 3-phosphoinositide-dependent protein kinase 1 [Erinaceus
            europaeus]
          Length = 530

 Score =  449 bits (1154), Expect = e-149
 Identities = 231/487 (47%), Positives = 317/487 (65%), Gaps = 9/487 (1%)
 Frame = +1

Query: 1    SDNSQQTLKTHTPFVRKKGVKDFEFGKTLGEGSYSTVVAARDRSNGREYAVXXXXXXXXX 180
            S + Q T     P  RKK  +DF+FGK LGEGS+STVV AR+ +  REYA+         
Sbjct: 35   SSSLQHTAAQPPPQPRKKRPEDFKFGKILGEGSFSTVVLARELATSREYAIKILEKRHII 94

Query: 181  XXXXXXYVNIEKNTLNKMNHPGIVRLYFTFQDTDSLYFVLDHAKNGELLTFIKKLGSFDL 360
                  YV  E++ +++++HP  V+LYFTFQD + LYF L +AKNGELL +I+K+GSFD 
Sbjct: 95   KENKVPYVTRERDVMSRLDHPFFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDE 154

Query: 361  NCTQYYAAQILSAIEYMHSQGVIHRDLKPENILLDDKMHVKVTDFGTAKILEQNADGEED 540
             CT++Y A+++SA+EY+H +GVIHRDLKPENILL++ MH+++TDFGTAK+L   +   + 
Sbjct: 155  TCTRFYTAELVSALEYLHGKGVIHRDLKPENILLNEDMHIQITDFGTAKVLLPES---KQ 211

Query: 541  DRANSFVGTAEYVSPELLKEKAACKSSDFWALGCIIYQLIAGRPPFKGANEYRTFQKIVN 720
             RANSFVGTA+YVSPELL EK+ACKSSD WALGCIIYQL+AG PPF+  NEY  FQKI+ 
Sbjct: 212  ARANSFVGTAQYVSPELLTEKSACKSSDLWALGCIIYQLVAGLPPFRAGNEYLIFQKIIK 271

Query: 721  LEYSFPDGFPPVARDLVQKLLVLNPSERLGSGGKAGVERLKAHPFFQGIDWDILWQQPAP 900
            LEY FP+ F P ARDLV+KLLVL+ ++RLG     G   LKAHPFF+ I W+ L  Q  P
Sbjct: 272  LEYDFPEKFFPKARDLVEKLLVLDATKRLGCEEMGGYSPLKAHPFFESITWENLQHQTPP 331

Query: 901  RLLPYLPPNPQHNDPEFRTPTSAYLR----KLSDHSGEANSSPIATGLKHNDPFRLESWA 1068
            +L  YLP   + ++  +    +   +    ++S  S   + S   TGL H     +E + 
Sbjct: 332  KLTAYLPAMSEDDEDCYGNYDNLLSQFGCMQVSASSSSHSLSCTDTGLPHRAGSNIEQYI 391

Query: 1069 GGDDSPD-----KVDPEKVKKLEEQKRTSSQWIPFILKSELIIKTGPINKRKGFFSKKRT 1233
               DS       +   ++ + L E++ + + W  F+ ++ LI+K GP++KRKG F+++R 
Sbjct: 392  HDLDSNSFELDLQFSEDEKRLLLEKQASGNPWHQFV-ENNLILKMGPVDKRKGLFARRRQ 450

Query: 1234 LILTDFPRLIYVDQEKNSQKGEIYWSSRMVVELKNKRNFFIHTPRKTYYFEDPNNAAHEW 1413
            L+LT+ P L YVD      KGEI WS  +  E KN + FF+HTP +TYY  DP+  AH+W
Sbjct: 451  LLLTEGPHLYYVDPVNKVLKGEIPWSQELRPEAKNFKTFFVHTPNRTYYLMDPSGNAHKW 510

Query: 1414 VTKINEL 1434
              KI E+
Sbjct: 511  CRKIQEV 517


>ref|XP_008061434.1| 3-phosphoinositide-dependent protein kinase 1 [Carlito syrichta]
 ref|XP_021570796.1| 3-phosphoinositide-dependent protein kinase 1 [Carlito syrichta]
          Length = 531

 Score =  449 bits (1154), Expect = e-149
 Identities = 232/492 (47%), Positives = 318/492 (64%), Gaps = 9/492 (1%)
 Frame = +1

Query: 1    SDNSQQTLKTHTPFVRKKGVKDFEFGKTLGEGSYSTVVAARDRSNGREYAVXXXXXXXXX 180
            S +S Q      P  RKK  +DF+FGK LGEGS+STVV AR+ +  REYA+         
Sbjct: 35   SASSLQHATQPPPQPRKKRPEDFKFGKILGEGSFSTVVLARELATSREYAIKILEKRHII 94

Query: 181  XXXXXXYVNIEKNTLNKMNHPGIVRLYFTFQDTDSLYFVLDHAKNGELLTFIKKLGSFDL 360
                  YV  E++ +++++HP  V+LYFTFQD + LYF L +AKNGELL +I+K+GSFD 
Sbjct: 95   KENKVPYVTRERDVMSRLDHPFFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDE 154

Query: 361  NCTQYYAAQILSAIEYMHSQGVIHRDLKPENILLDDKMHVKVTDFGTAKILEQNADGEED 540
             CT++Y A+I+SA+EY+H +G+IHRDLKPENILL++ MH+++TDFGTAK+L   +   + 
Sbjct: 155  TCTRFYTAEIVSALEYLHGKGIIHRDLKPENILLNEDMHIQITDFGTAKVLSPES---KQ 211

Query: 541  DRANSFVGTAEYVSPELLKEKAACKSSDFWALGCIIYQLIAGRPPFKGANEYRTFQKIVN 720
             RANSFVGTA+YVSPELL EK+ACKSSD WALGCIIYQL+AG PPF+  NEY  FQKI+ 
Sbjct: 212  ARANSFVGTAQYVSPELLTEKSACKSSDLWALGCIIYQLVAGLPPFRAGNEYLIFQKIIK 271

Query: 721  LEYSFPDGFPPVARDLVQKLLVLNPSERLGSGGKAGVERLKAHPFFQGIDWDILWQQPAP 900
            LEY FP+ F P ARDLV+KLLVL+ ++RLG     G E LKAHPFF+ I W+ L QQ  P
Sbjct: 272  LEYDFPEKFFPKARDLVEKLLVLDATKRLGCEEMEGYEPLKAHPFFESITWENLHQQTPP 331

Query: 901  RLLPYLPPNPQHNDPEFRTPTSAYLR----KLSDHSGEANSSPIATGLKHNDPFRLESWA 1068
            +L  YLP   + ++  +    +   +    ++S  S   + S   TGL       +E + 
Sbjct: 332  KLTAYLPAMSEDDEDCYGNYDNLLSQFGCMQVSSSSSSHSFSASDTGLPQRSGSNIEQYI 391

Query: 1069 GGDDSPD-----KVDPEKVKKLEEQKRTSSQWIPFILKSELIIKTGPINKRKGFFSKKRT 1233
               D+       +   ++ + L E++   + W  F+ ++ LI+K GP++KRKG F+++R 
Sbjct: 392  HDLDTNSFELDLQFSEDEKRLLLEKQAGGNPWHQFV-ENNLILKMGPVDKRKGLFARRRQ 450

Query: 1234 LILTDFPRLIYVDQEKNSQKGEIYWSSRMVVELKNKRNFFIHTPRKTYYFEDPNNAAHEW 1413
            L+LT+ P L YVD      KGEI WS  +  E KN + FF+HTP +TYY  DP+  AH+W
Sbjct: 451  LLLTEGPHLYYVDPVNKVLKGEIPWSQELRPEAKNFKTFFVHTPNRTYYLMDPSGNAHKW 510

Query: 1414 VTKINELLVANY 1449
              KI E+    Y
Sbjct: 511  CRKIQEVWRQRY 522


>ref|XP_021089426.1| 3-phosphoinositide-dependent protein kinase 1 isoform X1
            [Mesocricetus auratus]
          Length = 532

 Score =  449 bits (1154), Expect = e-149
 Identities = 228/480 (47%), Positives = 315/480 (65%), Gaps = 9/480 (1%)
 Frame = +1

Query: 37   PFVRKKGVKDFEFGKTLGEGSYSTVVAARDRSNGREYAVXXXXXXXXXXXXXXXYVNIEK 216
            P  RKK  +DF+FGK LGEGS+STVV AR+ +  REYA+               YV  E+
Sbjct: 48   PQPRKKRPEDFKFGKILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRER 107

Query: 217  NTLNKMNHPGIVRLYFTFQDTDSLYFVLDHAKNGELLTFIKKLGSFDLNCTQYYAAQILS 396
            + +++++HP  V+LYFTFQD + LYF L +AKNGELL +I+K+GSFD  CT++Y A+I+S
Sbjct: 108  DVMSRLDHPFFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVS 167

Query: 397  AIEYMHSQGVIHRDLKPENILLDDKMHVKVTDFGTAKILEQNADGEEDDRANSFVGTAEY 576
            A+EY+H +G+IHRDLKPENILL++ MH+++TDFGTAK+L   +   +  RANSFVGTA+Y
Sbjct: 168  ALEYLHGKGIIHRDLKPENILLNEDMHIQITDFGTAKVLSPES---KQARANSFVGTAQY 224

Query: 577  VSPELLKEKAACKSSDFWALGCIIYQLIAGRPPFKGANEYRTFQKIVNLEYSFPDGFPPV 756
            VSPELL EK+ACKSSD WALGCIIYQL+AG PPF+  NEY  FQKI+ LEY FP+ F P 
Sbjct: 225  VSPELLTEKSACKSSDLWALGCIIYQLVAGLPPFRAGNEYLIFQKIIKLEYDFPEKFFPK 284

Query: 757  ARDLVQKLLVLNPSERLGSGGKAGVERLKAHPFFQGIDWDILWQQPAPRLLPYLPPNPQH 936
            ARDLV+KLLVL+ ++RLG     G E LKAHPFF+ I W+ L QQ  P+L  YLP   + 
Sbjct: 285  ARDLVEKLLVLDATKRLGCEEMEGYEPLKAHPFFESITWENLHQQTPPKLTAYLPAMSED 344

Query: 937  NDPEFRTPTSAYLR----KLSDHSGEANSSPIATGLKHNDPFRLESWAGGDDSPD----- 1089
            ++  +    +   +    ++S  S   + S + T L       +E +    D+       
Sbjct: 345  DEDCYGNYDNLLSQFGCMQVSSSSSSHSLSAVDTSLPQRSGSNIEQYIHDLDTNSFELDL 404

Query: 1090 KVDPEKVKKLEEQKRTSSQWIPFILKSELIIKTGPINKRKGFFSKKRTLILTDFPRLIYV 1269
            +   ++ + L E++ + + W  F+ ++ LI+K GP++KRKG F+++R L+LT+ P L YV
Sbjct: 405  QFSEDEKRLLLEKQASGNPWHQFV-ENNLILKMGPVDKRKGLFARRRQLLLTEGPHLYYV 463

Query: 1270 DQEKNSQKGEIYWSSRMVVELKNKRNFFIHTPRKTYYFEDPNNAAHEWVTKINELLVANY 1449
            D      KGEI WS  +  E KN + FF+HTP +TYY  DP+  AH+W  KI E+    Y
Sbjct: 464  DPVNKVLKGEIPWSQELRPEAKNFKTFFVHTPNRTYYLMDPSGNAHKWCRKIQEVWRQRY 523


>ref|XP_006979015.1| PREDICTED: 3-phosphoinositide-dependent protein kinase 1 [Peromyscus
            maniculatus bairdii]
 ref|XP_016834747.1| PREDICTED: 3-phosphoinositide-dependent protein kinase 1 [Cricetulus
            griseus]
          Length = 532

 Score =  449 bits (1154), Expect = e-149
 Identities = 228/480 (47%), Positives = 315/480 (65%), Gaps = 9/480 (1%)
 Frame = +1

Query: 37   PFVRKKGVKDFEFGKTLGEGSYSTVVAARDRSNGREYAVXXXXXXXXXXXXXXXYVNIEK 216
            P  RKK  +DF+FGK LGEGS+STVV AR+ +  REYA+               YV  E+
Sbjct: 48   PQPRKKRPEDFKFGKILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRER 107

Query: 217  NTLNKMNHPGIVRLYFTFQDTDSLYFVLDHAKNGELLTFIKKLGSFDLNCTQYYAAQILS 396
            + +++++HP  V+LYFTFQD + LYF L +AKNGELL +I+K+GSFD  CT++Y A+I+S
Sbjct: 108  DVMSRLDHPFFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVS 167

Query: 397  AIEYMHSQGVIHRDLKPENILLDDKMHVKVTDFGTAKILEQNADGEEDDRANSFVGTAEY 576
            A+EY+H +G+IHRDLKPENILL++ MH+++TDFGTAK+L   +   +  RANSFVGTA+Y
Sbjct: 168  ALEYLHGKGIIHRDLKPENILLNEDMHIQITDFGTAKVLSPES---KQARANSFVGTAQY 224

Query: 577  VSPELLKEKAACKSSDFWALGCIIYQLIAGRPPFKGANEYRTFQKIVNLEYSFPDGFPPV 756
            VSPELL EK+ACKSSD WALGCIIYQL+AG PPF+  NEY  FQKI+ LEY FP+ F P 
Sbjct: 225  VSPELLTEKSACKSSDLWALGCIIYQLVAGLPPFRAGNEYLIFQKIIKLEYDFPEKFFPK 284

Query: 757  ARDLVQKLLVLNPSERLGSGGKAGVERLKAHPFFQGIDWDILWQQPAPRLLPYLPPNPQH 936
            ARDLV+KLLVL+ ++RLG     G E LKAHPFF+ I W+ L QQ  P+L  YLP   + 
Sbjct: 285  ARDLVEKLLVLDATKRLGCEEMEGYEPLKAHPFFESITWENLHQQTPPKLTAYLPAMSED 344

Query: 937  NDPEFRTPTSAYLR----KLSDHSGEANSSPIATGLKHNDPFRLESWAGGDDSPD----- 1089
            ++  +    +   +    ++S  S   + S + T L       +E +    D+       
Sbjct: 345  DEDCYGNYDNLLSQFGCMQVSSSSSSHSLSAVDTSLPQRSGSNIEQYIHDLDTNSFELDL 404

Query: 1090 KVDPEKVKKLEEQKRTSSQWIPFILKSELIIKTGPINKRKGFFSKKRTLILTDFPRLIYV 1269
            +   ++ + L E++ + + W  F+ ++ LI+K GP++KRKG F+++R L+LT+ P L YV
Sbjct: 405  QFSEDEKRLLLEKQASGNPWHQFV-ENNLILKMGPVDKRKGLFARRRQLLLTEGPHLYYV 463

Query: 1270 DQEKNSQKGEIYWSSRMVVELKNKRNFFIHTPRKTYYFEDPNNAAHEWVTKINELLVANY 1449
            D      KGEI WS  +  E KN + FF+HTP +TYY  DP+  AH+W  KI E+    Y
Sbjct: 464  DPVNKVLKGEIPWSQELRPEAKNFKTFFVHTPNRTYYLMDPSGNAHKWCRKIQEVWRQRY 523


>ref|XP_007606614.1| PREDICTED: 3-phosphoinositide-dependent protein kinase 1 [Cricetulus
            griseus]
          Length = 532

 Score =  448 bits (1153), Expect = e-149
 Identities = 228/480 (47%), Positives = 315/480 (65%), Gaps = 9/480 (1%)
 Frame = +1

Query: 37   PFVRKKGVKDFEFGKTLGEGSYSTVVAARDRSNGREYAVXXXXXXXXXXXXXXXYVNIEK 216
            P  RKK  +DF+FGK LGEGS+STVV AR+ +  REYA+               YV  E+
Sbjct: 48   PQPRKKRPEDFKFGKILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRER 107

Query: 217  NTLNKMNHPGIVRLYFTFQDTDSLYFVLDHAKNGELLTFIKKLGSFDLNCTQYYAAQILS 396
            + +++++HP  V+LYFTFQD + LYF L +AKNGELL +I+K+GSFD  CT++Y A+I+S
Sbjct: 108  DVMSRLDHPFFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVS 167

Query: 397  AIEYMHSQGVIHRDLKPENILLDDKMHVKVTDFGTAKILEQNADGEEDDRANSFVGTAEY 576
            A+EY+H +G+IHRDLKPENILL++ MH+++TDFGTAK+L   +   +  RANSFVGTA+Y
Sbjct: 168  ALEYLHGKGIIHRDLKPENILLNEDMHIQITDFGTAKVLSPES---KQARANSFVGTAQY 224

Query: 577  VSPELLKEKAACKSSDFWALGCIIYQLIAGRPPFKGANEYRTFQKIVNLEYSFPDGFPPV 756
            VSPELL EK+ACKSSD WALGCIIYQL+AG PPF+  NEY  FQKI+ LEY FP+ F P 
Sbjct: 225  VSPELLTEKSACKSSDLWALGCIIYQLVAGLPPFRAGNEYLIFQKIIKLEYDFPEKFFPK 284

Query: 757  ARDLVQKLLVLNPSERLGSGGKAGVERLKAHPFFQGIDWDILWQQPAPRLLPYLPPNPQH 936
            ARDLV+KLLVL+ ++RLG     G E LKAHPFF+ I W+ L QQ  P+L  YLP   + 
Sbjct: 285  ARDLVEKLLVLDATKRLGCEEMEGYEPLKAHPFFESITWENLHQQTPPKLTAYLPAMSED 344

Query: 937  NDPEFRTPTSAYLR----KLSDHSGEANSSPIATGLKHNDPFRLESWAGGDDSPD----- 1089
            ++  +    +   +    ++S  S   + S + T L       +E +    D+       
Sbjct: 345  DEDCYGNYDNLLSQFGCMQVSSSSSSHSLSAVDTSLPQRSGSNIEQYIHDLDTNSFELDL 404

Query: 1090 KVDPEKVKKLEEQKRTSSQWIPFILKSELIIKTGPINKRKGFFSKKRTLILTDFPRLIYV 1269
            +   ++ + L E++ + + W  F+ ++ LI+K GP++KRKG F+++R L+LT+ P L YV
Sbjct: 405  QFSEDEKRLLLEKQASGNPWHQFV-ENNLILKMGPVDKRKGLFARRRQLLLTEGPHLYYV 463

Query: 1270 DQEKNSQKGEIYWSSRMVVELKNKRNFFIHTPRKTYYFEDPNNAAHEWVTKINELLVANY 1449
            D      KGEI WS  +  E KN + FF+HTP +TYY  DP+  AH+W  KI E+    Y
Sbjct: 464  DPVNKVLKGEIPWSHELRPEAKNFKTFFVHTPNRTYYLMDPSGNAHKWCRKIQEVWRQRY 523


>gb|EHA99237.1| 3-phosphoinositide-dependent protein kinase 1 [Heterocephalus glaber]
          Length = 531

 Score =  448 bits (1152), Expect = e-149
 Identities = 230/492 (46%), Positives = 316/492 (64%), Gaps = 9/492 (1%)
 Frame = +1

Query: 1    SDNSQQTLKTHTPFVRKKGVKDFEFGKTLGEGSYSTVVAARDRSNGREYAVXXXXXXXXX 180
            S N  Q      P  RKK  +DF+FGK LGEGS+STVV AR+ +  REYA+         
Sbjct: 35   SANPLQHAAQPPPQPRKKRPEDFKFGKILGEGSFSTVVLARELATSREYAIKILEKRHII 94

Query: 181  XXXXXXYVNIEKNTLNKMNHPGIVRLYFTFQDTDSLYFVLDHAKNGELLTFIKKLGSFDL 360
                  YV  E++ +++++HP  ++LYFTFQD + LYF L +AKNGELL +I+K+GSFD 
Sbjct: 95   KENKVPYVTRERDVMSRLDHPFFIKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDE 154

Query: 361  NCTQYYAAQILSAIEYMHSQGVIHRDLKPENILLDDKMHVKVTDFGTAKILEQNADGEED 540
             CT++Y A+I+SA+EY+H +G+IHRDLKPENILL++ MH+++TDFGTAK+L   +   + 
Sbjct: 155  TCTRFYTAEIVSALEYLHGKGIIHRDLKPENILLNEDMHIQITDFGTAKVLSPES---KQ 211

Query: 541  DRANSFVGTAEYVSPELLKEKAACKSSDFWALGCIIYQLIAGRPPFKGANEYRTFQKIVN 720
             RANSFVGTA+YVSPELL EK+ACKSSD WALGCIIYQL+AG PPF+  NEY  FQKI+ 
Sbjct: 212  ARANSFVGTAQYVSPELLTEKSACKSSDLWALGCIIYQLVAGLPPFRAGNEYLIFQKIIK 271

Query: 721  LEYSFPDGFPPVARDLVQKLLVLNPSERLGSGGKAGVERLKAHPFFQGIDWDILWQQPAP 900
            LEY FP+ F P ARDLV+KLLVL+ ++RLG     G E LKAHPFF+ I W  L QQ  P
Sbjct: 272  LEYDFPEKFFPKARDLVEKLLVLDATKRLGCEEMKGYEPLKAHPFFESITWKNLHQQTPP 331

Query: 901  RLLPYLPPNPQHNDPEFRTPTSAYLR----KLSDHSGEANSSPIATGLKHNDPFRLESWA 1068
            +L  YLP   + ++  +    +   +    ++S  S   + S +   L H     +E + 
Sbjct: 332  KLTAYLPAMSEDDEDCYGNYDNLLSQFGCMQVSSSSSSHSLSVVDASLPHRSDSNIEQYI 391

Query: 1069 GGDDSPD-----KVDPEKVKKLEEQKRTSSQWIPFILKSELIIKTGPINKRKGFFSKKRT 1233
               D+       +   ++ + L E++   + W  F+ ++ LI+K GP++KRKG F+++R 
Sbjct: 392  HDLDTNSFELDLQFSEDEKRLLLEKQAGGNPWHQFV-ENNLILKMGPVDKRKGLFARRRQ 450

Query: 1234 LILTDFPRLIYVDQEKNSQKGEIYWSSRMVVELKNKRNFFIHTPRKTYYFEDPNNAAHEW 1413
            L+LT+ P L YVD      KGEI WS  +  E KN + FF+HTP +TYY  DP+  AH+W
Sbjct: 451  LLLTEGPHLYYVDPVNKVLKGEIPWSQELRPEAKNFKTFFVHTPNRTYYLMDPSGNAHKW 510

Query: 1414 VTKINELLVANY 1449
              KI E+    Y
Sbjct: 511  CRKIQEVWRQRY 522