BLASTX 2.2.26 [Sep-21-2011]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= Ophiopogon27_contig00044897
         (793 letters)

Database: All non-redundant GenBank CDS
translations+PDB+SwissProt+PIR+PRF excluding environmental samples
from WGS projects 
           149,584,005 sequences; 54,822,741,787 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

dbj|GBC37009.1| mucin-2 [Rhizophagus irregularis DAOM 181602]         385   e-126
gb|PKC70376.1| hypothetical protein RhiirA1_439473 [Rhizophagus ...   385   e-126
gb|EXX51031.1| hypothetical protein RirG_265260 [Rhizophagus irr...   385   e-126
gb|PKY48205.1| hypothetical protein RhiirA4_544463 [Rhizophagus ...   306   e-101
gb|PKK69560.1| hypothetical protein RhiirC2_748202, partial [Rhi...   191   8e-58
gb|POG72608.1| hypothetical protein GLOIN_2v1593383 [Rhizophagus...   191   6e-57
ref|XP_022203990.1| DNA-directed RNA polymerase II subunit RPB1-...    79   8e-13
ref|XP_021324641.1| filaggrin-2-like isoform X6 [Danio rerio]          77   4e-12
ref|XP_021324640.1| filaggrin-2-like isoform X5 [Danio rerio]          75   2e-11
ref|XP_017208498.1| filaggrin-2-like isoform X4 [Danio rerio]          75   2e-11
ref|XP_021324639.1| filaggrin-2-like isoform X3 [Danio rerio]          75   2e-11
ref|XP_009293378.1| filaggrin-2-like isoform X2 [Danio rerio]          75   2e-11
ref|XP_009293374.1| filaggrin-2-like isoform X1 [Danio rerio]          75   2e-11
ref|XP_014040269.1| PREDICTED: TBC1 domain family member 30-like...    67   1e-08
ref|XP_015198316.1| PREDICTED: mucin-2 [Lepisosteus oculatus]          65   2e-08
ref|XP_008469257.1| PREDICTED: uncharacterized protein DDB_G0283...    64   8e-08
emb|CRH00261.1| conserved Plasmodium protein, unknown function [...    63   2e-07
ref|XP_009061035.1| hypothetical protein LOTGIDRAFT_165765 [Lott...    59   3e-07
gb|OAG31008.1| hypothetical protein NEIG_00605 [Nematocida sp. E...    61   3e-07
ref|XP_014857843.1| PREDICTED: merozoite surface protein CMZ-8-l...    56   4e-06

>dbj|GBC37009.1| mucin-2 [Rhizophagus irregularis DAOM 181602]
          Length = 746

 Score =  385 bits (988), Expect = e-126
 Identities = 195/239 (81%), Positives = 199/239 (83%)
 Frame = +2

Query: 77   MNSPHSDVKLNIGSSHLNVTNPYSNFGYXXXXXXXXXXXXXTGLHNPQSGVTNSHLNNLN 256
            MNS HSDVKLN+GSSHLNVTNPYSNFGY             TGLHNPQSGVTNSHLN   
Sbjct: 413  MNSSHSDVKLNVGSSHLNVTNPYSNFGYSPNPPPHLNNSSLTGLHNPQSGVTNSHLN--- 469

Query: 257  MGSLHTAINNLHSGLSNPHSSVTNPHNPHSSTHNPYSSVTNPHNPQSSITSSHFNINTNP 436
            MGSLHTAINNLHSGLSNPHSSVTNPHNPHSS HNPYSSVTNPHNPQSSITSSHFN+NTNP
Sbjct: 470  MGSLHTAINNLHSGLSNPHSSVTNPHNPHSSAHNPYSSVTNPHNPQSSITSSHFNMNTNP 529

Query: 437  HLSMGSPHSNVNNSSHLTMDSPRSNVDSSFATNITSPHSHLNSSYXXXXXXXXXXXXXXX 616
            HLSMG PHSNVNNSSHLTMDSPRSNVDSSFATNITSPHSHLNSSY               
Sbjct: 530  HLSMGGPHSNVNNSSHLTMDSPRSNVDSSFATNITSPHSHLNSSYLNVNNPHTNNNSSHL 589

Query: 617  XEITASRVLPNYSHEVSNIKIEESNPLSPQNMDIPIIKPEESNIRDQLQSNTPTSSPIS 793
             EITAS VLPNYSHEVSNIKIEESNPLSPQ+MDIPIIKPEESNIRDQLQ+    SSPIS
Sbjct: 590  NEITASLVLPNYSHEVSNIKIEESNPLSPQSMDIPIIKPEESNIRDQLQT---ASSPIS 645


>gb|PKC70376.1| hypothetical protein RhiirA1_439473 [Rhizophagus irregularis]
 gb|PKY28559.1| hypothetical protein RhiirB3_36152 [Rhizophagus irregularis]
          Length = 754

 Score =  385 bits (988), Expect = e-126
 Identities = 195/239 (81%), Positives = 199/239 (83%)
 Frame = +2

Query: 77   MNSPHSDVKLNIGSSHLNVTNPYSNFGYXXXXXXXXXXXXXTGLHNPQSGVTNSHLNNLN 256
            MNS HSDVKLN+GSSHLNVTNPYSNFGY             TGLHNPQSGVTNSHLN   
Sbjct: 421  MNSSHSDVKLNVGSSHLNVTNPYSNFGYSPNPPSHLNNSSLTGLHNPQSGVTNSHLN--- 477

Query: 257  MGSLHTAINNLHSGLSNPHSSVTNPHNPHSSTHNPYSSVTNPHNPQSSITSSHFNINTNP 436
            MGSLHTAINNLHSGLSNPHSSVTNPHNPHSS HNPYSSVTNPHNPQSSITSSHFN+NTNP
Sbjct: 478  MGSLHTAINNLHSGLSNPHSSVTNPHNPHSSAHNPYSSVTNPHNPQSSITSSHFNMNTNP 537

Query: 437  HLSMGSPHSNVNNSSHLTMDSPRSNVDSSFATNITSPHSHLNSSYXXXXXXXXXXXXXXX 616
            HLSMG PHSNVNNSSHLTMDSPRSNVDSSFATNITSPHSHLNSSY               
Sbjct: 538  HLSMGGPHSNVNNSSHLTMDSPRSNVDSSFATNITSPHSHLNSSYLNVNNPHTNNNSSHL 597

Query: 617  XEITASRVLPNYSHEVSNIKIEESNPLSPQNMDIPIIKPEESNIRDQLQSNTPTSSPIS 793
             EITAS VLPNYSHEVSNIKIEESNPLSPQ+MDIPIIKPEESNIRDQLQ+    SSPIS
Sbjct: 598  NEITASLVLPNYSHEVSNIKIEESNPLSPQSMDIPIIKPEESNIRDQLQT---ASSPIS 653


>gb|EXX51031.1| hypothetical protein RirG_265260 [Rhizophagus irregularis DAOM
            197198w]
 gb|PKC01182.1| hypothetical protein RhiirA5_504757 [Rhizophagus irregularis]
          Length = 754

 Score =  385 bits (988), Expect = e-126
 Identities = 195/239 (81%), Positives = 199/239 (83%)
 Frame = +2

Query: 77   MNSPHSDVKLNIGSSHLNVTNPYSNFGYXXXXXXXXXXXXXTGLHNPQSGVTNSHLNNLN 256
            MNS HSDVKLN+GSSHLNVTNPYSNFGY             TGLHNPQSGVTNSHLN   
Sbjct: 421  MNSSHSDVKLNVGSSHLNVTNPYSNFGYSPNPPPHLNNSSLTGLHNPQSGVTNSHLN--- 477

Query: 257  MGSLHTAINNLHSGLSNPHSSVTNPHNPHSSTHNPYSSVTNPHNPQSSITSSHFNINTNP 436
            MGSLHTAINNLHSGLSNPHSSVTNPHNPHSS HNPYSSVTNPHNPQSSITSSHFN+NTNP
Sbjct: 478  MGSLHTAINNLHSGLSNPHSSVTNPHNPHSSAHNPYSSVTNPHNPQSSITSSHFNMNTNP 537

Query: 437  HLSMGSPHSNVNNSSHLTMDSPRSNVDSSFATNITSPHSHLNSSYXXXXXXXXXXXXXXX 616
            HLSMG PHSNVNNSSHLTMDSPRSNVDSSFATNITSPHSHLNSSY               
Sbjct: 538  HLSMGGPHSNVNNSSHLTMDSPRSNVDSSFATNITSPHSHLNSSYLNVNNPHTNNNSSHL 597

Query: 617  XEITASRVLPNYSHEVSNIKIEESNPLSPQNMDIPIIKPEESNIRDQLQSNTPTSSPIS 793
             EITAS VLPNYSHEVSNIKIEESNPLSPQ+MDIPIIKPEESNIRDQLQ+    SSPIS
Sbjct: 598  NEITASLVLPNYSHEVSNIKIEESNPLSPQSMDIPIIKPEESNIRDQLQT---ASSPIS 653


>gb|PKY48205.1| hypothetical protein RhiirA4_544463 [Rhizophagus irregularis]
          Length = 277

 Score =  306 bits (784), Expect = e-101
 Identities = 153/179 (85%), Positives = 156/179 (87%)
 Frame = +2

Query: 257 MGSLHTAINNLHSGLSNPHSSVTNPHNPHSSTHNPYSSVTNPHNPQSSITSSHFNINTNP 436
           MGSLHTAINNLHSGLSNPHSSVTNPHNPHSS HNPYSSVTNPHNPQSSITSSHFN+NTNP
Sbjct: 1   MGSLHTAINNLHSGLSNPHSSVTNPHNPHSSAHNPYSSVTNPHNPQSSITSSHFNMNTNP 60

Query: 437 HLSMGSPHSNVNNSSHLTMDSPRSNVDSSFATNITSPHSHLNSSYXXXXXXXXXXXXXXX 616
           HLSMG PHSNVNNSSHLTMDSPRSNVDSSF TNITSPHSHLNSSY               
Sbjct: 61  HLSMGGPHSNVNNSSHLTMDSPRSNVDSSFTTNITSPHSHLNSSYLNVNNPHTNNNSSHL 120

Query: 617 XEITASRVLPNYSHEVSNIKIEESNPLSPQNMDIPIIKPEESNIRDQLQSNTPTSSPIS 793
            EITAS VLPNYSHEVSNIKIEESNPLSPQ+MDIPIIKPEESNIRDQLQ+   TSSPIS
Sbjct: 121 NEITASLVLPNYSHEVSNIKIEESNPLSPQSMDIPIIKPEESNIRDQLQT---TSSPIS 176


>gb|PKK69560.1| hypothetical protein RhiirC2_748202, partial [Rhizophagus
           irregularis]
          Length = 160

 Score =  191 bits (484), Expect = 8e-58
 Identities = 99/124 (79%), Positives = 102/124 (82%)
 Frame = +2

Query: 422 INTNPHLSMGSPHSNVNNSSHLTMDSPRSNVDSSFATNITSPHSHLNSSYXXXXXXXXXX 601
           +NTNPHLSMG PHSNVNNSSHLTMDSPRSNVDSSFATNITSPHSHLNSSY          
Sbjct: 1   MNTNPHLSMGGPHSNVNNSSHLTMDSPRSNVDSSFATNITSPHSHLNSSYLNVNNPHTNN 60

Query: 602 XXXXXXEITASRVLPNYSHEVSNIKIEESNPLSPQNMDIPIIKPEESNIRDQLQSNTPTS 781
                 EITAS VLPNYSHEVSNIKIEESNPLSPQ+MDIPIIKPEESNIRDQLQ+    S
Sbjct: 61  NSSHLNEITASLVLPNYSHEVSNIKIEESNPLSPQSMDIPIIKPEESNIRDQLQT---AS 117

Query: 782 SPIS 793
           SPIS
Sbjct: 118 SPIS 121


>gb|POG72608.1| hypothetical protein GLOIN_2v1593383 [Rhizophagus irregularis DAOM
           181602=DAOM 197198]
          Length = 222

 Score =  191 bits (484), Expect = 6e-57
 Identities = 99/124 (79%), Positives = 102/124 (82%)
 Frame = +2

Query: 422 INTNPHLSMGSPHSNVNNSSHLTMDSPRSNVDSSFATNITSPHSHLNSSYXXXXXXXXXX 601
           +NTNPHLSMG PHSNVNNSSHLTMDSPRSNVDSSFATNITSPHSHLNSSY          
Sbjct: 1   MNTNPHLSMGGPHSNVNNSSHLTMDSPRSNVDSSFATNITSPHSHLNSSYLNVNNPHTNN 60

Query: 602 XXXXXXEITASRVLPNYSHEVSNIKIEESNPLSPQNMDIPIIKPEESNIRDQLQSNTPTS 781
                 EITAS VLPNYSHEVSNIKIEESNPLSPQ+MDIPIIKPEESNIRDQLQ+    S
Sbjct: 61  NSSHLNEITASLVLPNYSHEVSNIKIEESNPLSPQSMDIPIIKPEESNIRDQLQT---AS 117

Query: 782 SPIS 793
           SPIS
Sbjct: 118 SPIS 121


>ref|XP_022203990.1| DNA-directed RNA polymerase II subunit RPB1-like, partial
           [Nilaparvata lugens]
          Length = 531

 Score = 78.6 bits (192), Expect = 8e-13
 Identities = 53/171 (30%), Positives = 90/171 (52%), Gaps = 8/171 (4%)
 Frame = +2

Query: 83  SPHSDVKLNIGSSHLNVTNPYSNFGYXXXXXXXXXXXXXTGLHNPQSGVTNSHLNNLNMG 262
           SPHS ++    S H  + +P+S                 + L +P S + + H     + 
Sbjct: 365 SPHSTLQ----SPHSTLQSPHSTL-----------QSPHSTLQSPHSTLQSPHST---LQ 406

Query: 263 SLHTAINNLHSGLSNPHSSVTNPH----NPHSSTHNPYSSVTNPH----NPQSSITSSHF 418
           S H+ + + HS L +PHS++ +PH    +PHS+  +P+S++ +PH    +P S++ S H 
Sbjct: 407 SPHSTLQSPHSTLQSPHSTLQSPHSTLQSPHSTLQSPHSTLQSPHSTLQSPHSTLQSPHS 466

Query: 419 NINTNPHLSMGSPHSNVNNSSHLTMDSPRSNVDSSFATNITSPHSHLNSSY 571
            +  +PH ++ SPHS +  S H T+ SP S + S  +T + SPHS L S +
Sbjct: 467 TLQ-SPHSTLQSPHSTL-QSPHSTLQSPHSTLQSPHST-LQSPHSTLQSPH 514



 Score = 75.9 bits (185), Expect = 7e-12
 Identities = 46/130 (35%), Positives = 78/130 (60%), Gaps = 8/130 (6%)
 Frame = +2

Query: 206 LHNPQSGVTNSHLNNLNMGSLHTAINNLHSGLSNPHSSVTNPH----NPHSSTHNPYSSV 373
           L++P S +  S ++ L   S H+ + + HS L +PHS++ +PH    +PHS+  +P+S++
Sbjct: 347 LYSPVSTLY-SPVSTLYSPSPHSTLQSPHSTLQSPHSTLQSPHSTLQSPHSTLQSPHSTL 405

Query: 374 TNPH----NPQSSITSSHFNINTNPHLSMGSPHSNVNNSSHLTMDSPRSNVDSSFATNIT 541
            +PH    +P S++ S H  +  +PH ++ SPHS +  S H T+ SP S + S  +T + 
Sbjct: 406 QSPHSTLQSPHSTLQSPHSTLQ-SPHSTLQSPHSTL-QSPHSTLQSPHSTLQSPHST-LQ 462

Query: 542 SPHSHLNSSY 571
           SPHS L S +
Sbjct: 463 SPHSTLQSPH 472



 Score = 66.2 bits (160), Expect = 1e-08
 Identities = 44/150 (29%), Positives = 78/150 (52%), Gaps = 4/150 (2%)
 Frame = +2

Query: 77  MNSPHSDVKLNIGSSHLNVTNPYSNFGYXXXXXXXXXXXXXTGLHNPQSGVTNSHLNNLN 256
           + SPHS ++    S H  + +P+S                 + L +P S + + H     
Sbjct: 405 LQSPHSTLQ----SPHSTLQSPHSTL-----------QSPHSTLQSPHSTLQSPHST--- 446

Query: 257 MGSLHTAINNLHSGLSNPHSSVTNPH----NPHSSTHNPYSSVTNPHNPQSSITSSHFNI 424
           + S H+ + + HS L +PHS++ +PH    +PHS+  +P+S++ +PH   S++ S H  +
Sbjct: 447 LQSPHSTLQSPHSTLQSPHSTLQSPHSTLQSPHSTLQSPHSTLQSPH---STLQSPHSTL 503

Query: 425 NTNPHLSMGSPHSNVNNSSHLTMDSPRSNV 514
             +PH ++ SPHS +  S H T+ SP S +
Sbjct: 504 Q-SPHSTLQSPHSTL-QSPHSTLQSPHSTL 531


>ref|XP_021324641.1| filaggrin-2-like isoform X6 [Danio rerio]
          Length = 1453

 Score = 77.0 bits (188), Expect = 4e-12
 Identities = 58/176 (32%), Positives = 79/176 (44%), Gaps = 18/176 (10%)
 Frame = +2

Query: 77  MNSPHSDVKLNIGSSHL---NVTNPYSNFGYXXXXXXXXXXXXXTGLHNPQSGVTNSHLN 247
           MN+PH  V     S H    +V NP+   G              +G HNP   V N H +
Sbjct: 340 MNNPHGSVVNPHKSGHNPHGSVVNPH---GSGHNPHGSVVNPHESG-HNPHGSVVNPHES 395

Query: 248 NLNMGSLHTAINNLHSGLSNPHSSVTNPH-----------NPHSSTHNPYSSVTNP---- 382
             N    H ++ N H    NPH SV NPH           NPH S HNP+ SV NP    
Sbjct: 396 GHNP---HGSVVNPHESGHNPHGSVVNPHESGHNPHGSVVNPHESGHNPHGSVVNPHESG 452

Query: 383 HNPQSSITSSHFNINTNPHLSMGSPHSNVNNSSHLTMDSPRSNVDSSFATNITSPH 550
           HNP  S+ + H     NPH S+ +PH + +N  H T+ +P  +  +    ++ +PH
Sbjct: 453 HNPHGSVVNPH-ESGHNPHGSVVNPHESGHN-PHGTVVNPHESGHNPHG-SVVNPH 505



 Score = 74.7 bits (182), Expect = 2e-11
 Identities = 58/202 (28%), Positives = 84/202 (41%), Gaps = 39/202 (19%)
 Frame = +2

Query: 83   SPHSDVKLNIGS---SHLNVTNPYSNFGYXXXXXXXXXXXXXTGLHNPQSGVTNSHLNNL 253
            +PH  V    GS   SH +V NP+ +                   HNP     N H +  
Sbjct: 979  NPHGSVANPHGSEHNSHGSVANPHGSE------------------HNPHGSEANPHGSEH 1020

Query: 254  NMGSLHTAINNLHSGLSNPHSSVTNPH------------------NPHSSTHNPYSSVTN 379
            N    H ++ N H     PH S  NPH                  NPH S HNP+ SV N
Sbjct: 1021 NS---HGSVANPHGSGHKPHGSEYNPHGSVANPLVSEYNTHGSVANPHGSAHNPHGSVAN 1077

Query: 380  PH------------------NPQSSITSSHFNINTNPHLSMGSPHSNVNNSSHLTMDSPR 505
            PH                  NPQ S  +SH ++  NPH S+ +PH++ +N SH ++ +P 
Sbjct: 1078 PHGSGHDPHGSEYNPHGSVENPQGSAPNSHGSV-ANPHGSVENPHASAHN-SHGSVANPH 1135

Query: 506  SNVDSSFATNITSPHSHLNSSY 571
             +  +S   ++ SPH   ++S+
Sbjct: 1136 GSAHNSHG-SVASPHGSAHNSH 1156



 Score = 70.9 bits (172), Expect = 4e-10
 Identities = 48/146 (32%), Positives = 69/146 (47%), Gaps = 32/146 (21%)
 Frame = +2

Query: 209  HNPQSGVTNSHLNNLNM--------GSLHT----------AINNLHSGLSNPHSSVTNPH 334
            HNP + V N H++            GS H           + +N H  + NPH S  NPH
Sbjct: 831  HNPHNPVVNPHVSEHKSHDPVVHPHGSGHNKHEPIVNPIGSGHNSHGSVVNPHGSEHNPH 890

Query: 335  ----NPHSSTHNPYSSVTNP----HNPQSSITSSHFNINTNPHLSMGSPHSNVNN----- 475
                NPH S HNP+ SV NP    HNP  S+ ++H     N H S+ +PH + NN     
Sbjct: 891  GSVVNPHGSEHNPHGSVVNPHGSEHNPHGSVVNTH-GSGHNSHGSVANPHGSENNPHGSE 949

Query: 476  -SSHLTMDSPRSNVDSSFATNITSPH 550
             +SH ++ +P  +   +F  +I +PH
Sbjct: 950  HNSHGSVANPHGS-GHTFHGSIANPH 974



 Score = 68.9 bits (167), Expect = 2e-09
 Identities = 44/114 (38%), Positives = 58/114 (50%), Gaps = 25/114 (21%)
 Frame = +2

Query: 209 HNPQSGVTNSHLNNLNM-GSLHTAIN---NLHSGLSNPHSSVTNPH----NPHSSTHNPY 364
           HNP   V N H +  N  GS+   ++   N H  + NPH S  NPH    NPH S HNP+
Sbjct: 509 HNPHGTVVNPHESGHNPHGSIVNPLDSGHNPHGSVVNPHGSGLNPHGSVVNPHESGHNPH 568

Query: 365 SSVTNP----HNPQSSITSSHFN--------INT-----NPHLSMGSPHSNVNN 475
            SV NP    HNP  S+ +SH +        +NT     NPH S+ +PH + +N
Sbjct: 569 GSVVNPHESGHNPHGSVVNSHESGHNPHGSVVNTHESGHNPHGSVVNPHESGHN 622



 Score = 68.6 bits (166), Expect = 3e-09
 Identities = 43/128 (33%), Positives = 62/128 (48%), Gaps = 15/128 (11%)
 Frame = +2

Query: 212 NPQSGVTNSHLNNLNMGSLHTAINNLHSGLSNPHSSVTNPH-----------NPHSSTHN 358
           NP   V N H +       H A+ N    ++NPH SV NPH           NPH S HN
Sbjct: 314 NPLESVVNIHESTHKS---HEAVVNPQESMNNPHGSVVNPHKSGHNPHGSVVNPHGSGHN 370

Query: 359 PYSSVTNP----HNPQSSITSSHFNINTNPHLSMGSPHSNVNNSSHLTMDSPRSNVDSSF 526
           P+ SV NP    HNP  S+ + H     NPH S+ +PH + +N  H ++ +P  +  +  
Sbjct: 371 PHGSVVNPHESGHNPHGSVVNPH-ESGHNPHGSVVNPHESGHN-PHGSVVNPHESGHNPH 428

Query: 527 ATNITSPH 550
             ++ +PH
Sbjct: 429 G-SVVNPH 435



 Score = 67.0 bits (162), Expect = 8e-09
 Identities = 39/104 (37%), Positives = 48/104 (46%), Gaps = 15/104 (14%)
 Frame = +2

Query: 209 HNPQSGVTNSHLNNLNMGSLHTAINNLHSGLSNPHSSVTNPH-----------NPHSSTH 355
           HNP   V N H +  N    H ++ N H    NPH SV NPH           NPH S H
Sbjct: 439 HNPHGSVVNPHESGHNP---HGSVVNPHESGHNPHGSVVNPHESGHNPHGTVVNPHESGH 495

Query: 356 NPYSSVTNP----HNPQSSITSSHFNINTNPHLSMGSPHSNVNN 475
           NP+ SV NP    HNP  ++         NPH S  +PH ++ N
Sbjct: 496 NPHGSVVNPHESGHNPHGTV--------VNPHESGHNPHGSIVN 531



 Score = 67.0 bits (162), Expect = 8e-09
 Identities = 43/129 (33%), Positives = 62/129 (48%), Gaps = 15/129 (11%)
 Frame = +2

Query: 209 HNPQSGVTNSHLNNLNMGSLHTAINNLHSGLSNPHSSVTNPH-----------NPHSSTH 355
           HNP   V N H +  N    H ++ N H    NPH +V NPH           NPH S H
Sbjct: 453 HNPHGSVVNPHESGHNP---HGSVVNPHESGHNPHGTVVNPHESGHNPHGSVVNPHESGH 509

Query: 356 NPYSSVTNP----HNPQSSITSSHFNINTNPHLSMGSPHSNVNNSSHLTMDSPRSNVDSS 523
           NP+ +V NP    HNP  SI +   +   NPH S+ +PH +  N  H ++ +P  +  + 
Sbjct: 510 NPHGTVVNPHESGHNPHGSIVNP-LDSGHNPHGSVVNPHGSGLN-PHGSVVNPHESGHNP 567

Query: 524 FATNITSPH 550
              ++ +PH
Sbjct: 568 HG-SVVNPH 575



 Score = 66.6 bits (161), Expect = 1e-08
 Identities = 52/181 (28%), Positives = 75/181 (41%), Gaps = 24/181 (13%)
 Frame = +2

Query: 80   NSPHSDVKLNIGS---SHLNVTNPYSNFGYXXXXXXXXXXXXXTGLHNPQSGVTNSHLNN 250
            ++PH  V    GS   SH +V NP+ +                   HN    V N H + 
Sbjct: 915  HNPHGSVVNTHGSGHNSHGSVANPHGSENNPHGSE-----------HNSHGSVANPHGSG 963

Query: 251  LNMGSLHTAINNLHSGLSNPHSSVTNPH-----------NPHSSTHNPYSSVTNP----H 385
                + H +I N H    NPH SV NPH           NPH S HNP+ S  NP    H
Sbjct: 964  ---HTFHGSIANPHVSAENPHGSVANPHGSEHNSHGSVANPHGSEHNPHGSEANPHGSEH 1020

Query: 386  NPQSSITSSHFNINTNPHLSMGSPHSNVNN------SSHLTMDSPRSNVDSSFATNITSP 547
            N   S+ + H      PH S  +PH +V N      ++H ++ +P  +  +    ++ +P
Sbjct: 1021 NSHGSVANPH-GSGHKPHGSEYNPHGSVANPLVSEYNTHGSVANPHGSAHNPHG-SVANP 1078

Query: 548  H 550
            H
Sbjct: 1079 H 1079



 Score = 66.2 bits (160), Expect = 2e-08
 Identities = 42/116 (36%), Positives = 54/116 (46%), Gaps = 15/116 (12%)
 Frame = +2

Query: 209 HNPQSGVTNSHLNNLNMGSLHTAINNLHSGLSNPHSSVTNPH-----------NPHSSTH 355
           HNP   V N H + LN    H ++ N H    NPH SV NPH           N H S H
Sbjct: 537 HNPHGSVVNPHGSGLNP---HGSVVNPHESGHNPHGSVVNPHESGHNPHGSVVNSHESGH 593

Query: 356 NPYSSVTNP----HNPQSSITSSHFNINTNPHLSMGSPHSNVNNSSHLTMDSPRSN 511
           NP+ SV N     HNP  S+ + H     NPH S+ + HS+    SH  + +P  +
Sbjct: 594 NPHGSVVNTHESGHNPHGSVVNPH-ESGHNPHGSVVNIHSS-EQKSHDPVGNPHGS 647



 Score = 57.8 bits (138), Expect = 1e-05
 Identities = 41/138 (29%), Positives = 62/138 (44%), Gaps = 7/138 (5%)
 Frame = +2

Query: 83   SPHSDVKLNIGS---SHLNVTNPYSNFGYXXXXXXXXXXXXXTGLHNPQSGVTNSHLNNL 253
            +PH  V+   GS   SH +V NP+ +                  + NP +   NSH +  
Sbjct: 1091 NPHGSVENPQGSAPNSHGSVANPHGS------------------VENPHASAHNSHGSVA 1132

Query: 254  NMGSLHTAINNLHSGLSNPHSSVTNPH----NPHSSTHNPYSSVTNPHNPQSSITSSHFN 421
            N    H + +N H  +++PH S  N H    NPH S HNP+ S    H P+      H +
Sbjct: 1133 NP---HGSAHNSHGSVASPHGSAHNSHGSGHNPHGSGHNPHESGHKTHGPRH---KPHGS 1186

Query: 422  INTNPHLSMGSPHSNVNN 475
            +   PH  M +PH +++N
Sbjct: 1187 V-VYPHEPMHNPHGHLHN 1203


>ref|XP_021324640.1| filaggrin-2-like isoform X5 [Danio rerio]
          Length = 1467

 Score = 74.7 bits (182), Expect = 2e-11
 Identities = 58/202 (28%), Positives = 84/202 (41%), Gaps = 39/202 (19%)
 Frame = +2

Query: 83   SPHSDVKLNIGS---SHLNVTNPYSNFGYXXXXXXXXXXXXXTGLHNPQSGVTNSHLNNL 253
            +PH  V    GS   SH +V NP+ +                   HNP     N H +  
Sbjct: 993  NPHGSVANPHGSEHNSHGSVANPHGSE------------------HNPHGSEANPHGSEH 1034

Query: 254  NMGSLHTAINNLHSGLSNPHSSVTNPH------------------NPHSSTHNPYSSVTN 379
            N    H ++ N H     PH S  NPH                  NPH S HNP+ SV N
Sbjct: 1035 NS---HGSVANPHGSGHKPHGSEYNPHGSVANPLVSEYNTHGSVANPHGSAHNPHGSVAN 1091

Query: 380  PH------------------NPQSSITSSHFNINTNPHLSMGSPHSNVNNSSHLTMDSPR 505
            PH                  NPQ S  +SH ++  NPH S+ +PH++ +N SH ++ +P 
Sbjct: 1092 PHGSGHDPHGSEYNPHGSVENPQGSAPNSHGSV-ANPHGSVENPHASAHN-SHGSVANPH 1149

Query: 506  SNVDSSFATNITSPHSHLNSSY 571
             +  +S   ++ SPH   ++S+
Sbjct: 1150 GSAHNSHG-SVASPHGSAHNSH 1170



 Score = 73.9 bits (180), Expect = 4e-11
 Identities = 45/117 (38%), Positives = 57/117 (48%), Gaps = 28/117 (23%)
 Frame = +2

Query: 209 HNPQSGVTNSHLNNLNMGSLHTAINNLHSGLSNPHSSVTNPH-----------NPHSSTH 355
           HNP   V N H + LN    H ++ N H    NPH SV NPH           NPH S H
Sbjct: 523 HNPHGSVVNPHGSGLNP---HGSVVNPHESGHNPHGSVVNPHESGHNPHGSVVNPHESGH 579

Query: 356 NPYSSVTNP----HNPQSSITSSHFN--------INT-----NPHLSMGSPHSNVNN 475
           NP+ SV NP    HNP  S+ +SH +        +NT     NPH S+ +PH + +N
Sbjct: 580 NPHGSVVNPHESGHNPHGSVVNSHESGHNPHGSVVNTHESGHNPHGSVVNPHESGHN 636



 Score = 71.2 bits (173), Expect = 3e-10
 Identities = 44/128 (34%), Positives = 64/128 (50%), Gaps = 15/128 (11%)
 Frame = +2

Query: 212 NPQSGVTNSHLNNLNMGSLHTAINNLHSGLSNPHSSVTNPH-----------NPHSSTHN 358
           NP   V N H +       H A+ N    ++NPH SV NPH           NPH S HN
Sbjct: 314 NPLESVVNIHESTHKS---HEAVVNPQESMNNPHGSVVNPHKSGHNPHGSVVNPHGSGHN 370

Query: 359 PYSSVTNP----HNPQSSITSSHFNINTNPHLSMGSPHSNVNNSSHLTMDSPRSNVDSSF 526
           P+ SV NP    HNP  S+ + H     NPH S+ +PH + +N  H ++ +P  +  +S+
Sbjct: 371 PHGSVVNPHESGHNPHGSVVNPH-ESGHNPHGSVVNPHESGHN-PHGSIVNPYESGHNSY 428

Query: 527 ATNITSPH 550
             ++ +PH
Sbjct: 429 G-SVVNPH 435



 Score = 70.9 bits (172), Expect = 4e-10
 Identities = 56/171 (32%), Positives = 71/171 (41%), Gaps = 25/171 (14%)
 Frame = +2

Query: 77  MNSPHSDVKLNIGSSHL---NVTNPYSNFGYXXXXXXXXXXXXXTGLHNPQSGVTNSHLN 247
           MN+PH  V     S H    +V NP+   G              +G HNP   V N H +
Sbjct: 340 MNNPHGSVVNPHKSGHNPHGSVVNPH---GSGHNPHGSVVNPHESG-HNPHGSVVNPHES 395

Query: 248 NLNMGSLHTAINNLHSGLSNPHSSVTNPH------------------NPHSSTHNPYSSV 373
             N    H ++ N H    NPH S+ NP+                  NPH S HNP+ SV
Sbjct: 396 GHNP---HGSVVNPHESGHNPHGSIVNPYESGHNSYGSVVNPHGSVVNPHGSGHNPHGSV 452

Query: 374 TNP----HNPQSSITSSHFNINTNPHLSMGSPHSNVNNSSHLTMDSPRSNV 514
            NP    HNP  SI + H     NPH S+  PH +V N  H +  +P   V
Sbjct: 453 VNPHESGHNPHGSIVNPH-GSGHNPHGSVVKPHGSVVN-PHESGHNPHGTV 501



 Score = 70.9 bits (172), Expect = 4e-10
 Identities = 48/146 (32%), Positives = 69/146 (47%), Gaps = 32/146 (21%)
 Frame = +2

Query: 209  HNPQSGVTNSHLNNLNM--------GSLHT----------AINNLHSGLSNPHSSVTNPH 334
            HNP + V N H++            GS H           + +N H  + NPH S  NPH
Sbjct: 845  HNPHNPVVNPHVSEHKSHDPVVHPHGSGHNKHEPIVNPIGSGHNSHGSVVNPHGSEHNPH 904

Query: 335  ----NPHSSTHNPYSSVTNP----HNPQSSITSSHFNINTNPHLSMGSPHSNVNN----- 475
                NPH S HNP+ SV NP    HNP  S+ ++H     N H S+ +PH + NN     
Sbjct: 905  GSVVNPHGSEHNPHGSVVNPHGSEHNPHGSVVNTH-GSGHNSHGSVANPHGSENNPHGSE 963

Query: 476  -SSHLTMDSPRSNVDSSFATNITSPH 550
             +SH ++ +P  +   +F  +I +PH
Sbjct: 964  HNSHGSVANPHGS-GHTFHGSIANPH 988



 Score = 70.1 bits (170), Expect = 8e-10
 Identities = 50/155 (32%), Positives = 72/155 (46%), Gaps = 12/155 (7%)
 Frame = +2

Query: 122 HLNVTNPY----SNFGYXXXXXXXXXXXXXTGLHNPQSGVTNSHLNNLNMGSLHTAINNL 289
           H ++ NPY    +++G              +G HNP   V N H +  N    H +I N 
Sbjct: 414 HGSIVNPYESGHNSYGSVVNPHGSVVNPHGSG-HNPHGSVVNPHESGHNP---HGSIVNP 469

Query: 290 HSGLSNPHSSVTNPH----NPHSSTHNPYSSVTNP----HNPQSSITSSHFNINTNPHLS 445
           H    NPH SV  PH    NPH S HNP+ +V NP    HNP  SI +       NPH S
Sbjct: 470 HGSGHNPHGSVVKPHGSVVNPHESGHNPHGTVVNPHESGHNPHGSIVNP-LESGHNPHGS 528

Query: 446 MGSPHSNVNNSSHLTMDSPRSNVDSSFATNITSPH 550
           + +PH +  N  H ++ +P  +  +    ++ +PH
Sbjct: 529 VVNPHGSGLN-PHGSVVNPHESGHNPHG-SVVNPH 561



 Score = 68.9 bits (167), Expect = 2e-09
 Identities = 45/136 (33%), Positives = 65/136 (47%), Gaps = 21/136 (15%)
 Frame = +2

Query: 206 LHNPQSGVTNSHLNNLNMGSLHTAINNLHSGLSNPHSSVTNPH-----------NPHSST 352
           ++NP   V N H +  N    H ++ N H    NPH SV NPH           NPH S 
Sbjct: 340 MNNPHGSVVNPHKSGHNP---HGSVVNPHGSGHNPHGSVVNPHESGHNPHGSVVNPHESG 396

Query: 353 HNPYSSVTNP----HNPQSSITSSH------FNINTNPHLSMGSPHSNVNNSSHLTMDSP 502
           HNP+ SV NP    HNP  SI + +      +    NPH S+ +PH + +N  H ++ +P
Sbjct: 397 HNPHGSVVNPHESGHNPHGSIVNPYESGHNSYGSVVNPHGSVVNPHGSGHN-PHGSVVNP 455

Query: 503 RSNVDSSFATNITSPH 550
             +  +    +I +PH
Sbjct: 456 HESGHNPHG-SIVNPH 470



 Score = 66.6 bits (161), Expect = 1e-08
 Identities = 52/181 (28%), Positives = 75/181 (41%), Gaps = 24/181 (13%)
 Frame = +2

Query: 80   NSPHSDVKLNIGS---SHLNVTNPYSNFGYXXXXXXXXXXXXXTGLHNPQSGVTNSHLNN 250
            ++PH  V    GS   SH +V NP+ +                   HN    V N H + 
Sbjct: 929  HNPHGSVVNTHGSGHNSHGSVANPHGSENNPHGSE-----------HNSHGSVANPHGSG 977

Query: 251  LNMGSLHTAINNLHSGLSNPHSSVTNPH-----------NPHSSTHNPYSSVTNP----H 385
                + H +I N H    NPH SV NPH           NPH S HNP+ S  NP    H
Sbjct: 978  ---HTFHGSIANPHVSAENPHGSVANPHGSEHNSHGSVANPHGSEHNPHGSEANPHGSEH 1034

Query: 386  NPQSSITSSHFNINTNPHLSMGSPHSNVNN------SSHLTMDSPRSNVDSSFATNITSP 547
            N   S+ + H      PH S  +PH +V N      ++H ++ +P  +  +    ++ +P
Sbjct: 1035 NSHGSVANPH-GSGHKPHGSEYNPHGSVANPLVSEYNTHGSVANPHGSAHNPHG-SVANP 1092

Query: 548  H 550
            H
Sbjct: 1093 H 1093



 Score = 63.9 bits (154), Expect = 9e-08
 Identities = 41/116 (35%), Positives = 53/116 (45%), Gaps = 15/116 (12%)
 Frame = +2

Query: 209 HNPQSGVTNSHLNNLNMGSLHTAINNLHSGLSNPHSSVTNPH-----------NPHSSTH 355
           HNP   V N H +  N    H ++ N H    NPH SV NPH           N H S H
Sbjct: 551 HNPHGSVVNPHESGHNP---HGSVVNPHESGHNPHGSVVNPHESGHNPHGSVVNSHESGH 607

Query: 356 NPYSSVTNP----HNPQSSITSSHFNINTNPHLSMGSPHSNVNNSSHLTMDSPRSN 511
           NP+ SV N     HNP  S+ + H     NPH S+ + HS+    SH  + +P  +
Sbjct: 608 NPHGSVVNTHESGHNPHGSVVNPH-ESGHNPHGSVVNIHSS-EQKSHDPVGNPHGS 661



 Score = 61.2 bits (147), Expect = 7e-07
 Identities = 45/123 (36%), Positives = 62/123 (50%), Gaps = 5/123 (4%)
 Frame = +2

Query: 209 HNPQSGVTNSHLNNLNM-GSLHTAINNLHSGLSNPHSSVTNPHNPHSSTHNPYSSVTNP- 382
           HNP   V N H +  N  GS+   +N L SG  NPH SV NPH    S  NP+ SV NP 
Sbjct: 495 HNPHGTVVNPHESGHNPHGSI---VNPLESG-HNPHGSVVNPHG---SGLNPHGSVVNPH 547

Query: 383 ---HNPQSSITSSHFNINTNPHLSMGSPHSNVNNSSHLTMDSPRSNVDSSFATNITSPHS 553
              HNP  S+ + H     NPH S+ +PH + +N  H ++ +P  +  +   + + S  S
Sbjct: 548 ESGHNPHGSVVNPH-ESGHNPHGSVVNPHESGHN-PHGSVVNPHESGHNPHGSVVNSHES 605

Query: 554 HLN 562
             N
Sbjct: 606 GHN 608



 Score = 57.8 bits (138), Expect = 1e-05
 Identities = 41/138 (29%), Positives = 62/138 (44%), Gaps = 7/138 (5%)
 Frame = +2

Query: 83   SPHSDVKLNIGS---SHLNVTNPYSNFGYXXXXXXXXXXXXXTGLHNPQSGVTNSHLNNL 253
            +PH  V+   GS   SH +V NP+ +                  + NP +   NSH +  
Sbjct: 1105 NPHGSVENPQGSAPNSHGSVANPHGS------------------VENPHASAHNSHGSVA 1146

Query: 254  NMGSLHTAINNLHSGLSNPHSSVTNPH----NPHSSTHNPYSSVTNPHNPQSSITSSHFN 421
            N    H + +N H  +++PH S  N H    NPH S HNP+ S    H P+      H +
Sbjct: 1147 NP---HGSAHNSHGSVASPHGSAHNSHGSGHNPHGSGHNPHESGHKTHGPRH---KPHGS 1200

Query: 422  INTNPHLSMGSPHSNVNN 475
            +   PH  M +PH +++N
Sbjct: 1201 V-VYPHEPMHNPHGHLHN 1217


>ref|XP_017208498.1| filaggrin-2-like isoform X4 [Danio rerio]
          Length = 1499

 Score = 74.7 bits (182), Expect = 2e-11
 Identities = 58/202 (28%), Positives = 84/202 (41%), Gaps = 39/202 (19%)
 Frame = +2

Query: 83   SPHSDVKLNIGS---SHLNVTNPYSNFGYXXXXXXXXXXXXXTGLHNPQSGVTNSHLNNL 253
            +PH  V    GS   SH +V NP+ +                   HNP     N H +  
Sbjct: 1025 NPHGSVANPHGSEHNSHGSVANPHGSE------------------HNPHGSEANPHGSEH 1066

Query: 254  NMGSLHTAINNLHSGLSNPHSSVTNPH------------------NPHSSTHNPYSSVTN 379
            N    H ++ N H     PH S  NPH                  NPH S HNP+ SV N
Sbjct: 1067 NS---HGSVANPHGSGHKPHGSEYNPHGSVANPLVSEYNTHGSVANPHGSAHNPHGSVAN 1123

Query: 380  PH------------------NPQSSITSSHFNINTNPHLSMGSPHSNVNNSSHLTMDSPR 505
            PH                  NPQ S  +SH ++  NPH S+ +PH++ +N SH ++ +P 
Sbjct: 1124 PHGSGHDPHGSEYNPHGSVENPQGSAPNSHGSV-ANPHGSVENPHASAHN-SHGSVANPH 1181

Query: 506  SNVDSSFATNITSPHSHLNSSY 571
             +  +S   ++ SPH   ++S+
Sbjct: 1182 GSAHNSHG-SVASPHGSAHNSH 1202



 Score = 72.4 bits (176), Expect = 1e-10
 Identities = 50/144 (34%), Positives = 66/144 (45%), Gaps = 29/144 (20%)
 Frame = +2

Query: 209 HNPQSGVTNSHLNNLNM-GSL----------HTAINNLHSGLSNPHSSVTNPH------- 334
           HNP   V N H + LN  GS+          H ++ N H    NPH SV NPH       
Sbjct: 443 HNPHGSVVNPHGSGLNPHGSVVNPHESGHNPHGSVVNPHESGHNPHGSVVNPHESGHNPH 502

Query: 335 ----NPHSSTHNPYSSVTNP----HNPQSSITSSHFNINTNPHLSMGSPHSNVNNSSHLT 490
               NPH S HNP+ SV NP    HNP  ++ + H     NPH S+ +PH + +N  H T
Sbjct: 503 GSVVNPHESGHNPHGSVVNPHESGHNPHGTVVNPH-ESGHNPHGSVVNPHESGHN-PHGT 560

Query: 491 MDSPRS---NVDSSFATNITSPHS 553
           + +P     N   S    + S H+
Sbjct: 561 VVNPHESGHNPHGSIVNPLDSGHN 584



 Score = 72.0 bits (175), Expect = 2e-10
 Identities = 46/126 (36%), Positives = 65/126 (51%), Gaps = 12/126 (9%)
 Frame = +2

Query: 209 HNPQSGVTNSHLNNLNM-GSLHTAI---NNLHSGLSNPHSSVTNPH----NPHSSTHNPY 364
           HNP   V N H +  N  GS+   +   +N H  + NPH S  NPH    NPH S HNP+
Sbjct: 415 HNPHGTVVNPHESGHNPHGSIVNPLESGHNPHGSVVNPHGSGLNPHGSVVNPHESGHNPH 474

Query: 365 SSVTNP----HNPQSSITSSHFNINTNPHLSMGSPHSNVNNSSHLTMDSPRSNVDSSFAT 532
            SV NP    HNP  S+ + H     NPH S+ +PH + +N  H ++ +P  +  +   T
Sbjct: 475 GSVVNPHESGHNPHGSVVNPH-ESGHNPHGSVVNPHESGHN-PHGSVVNPHESGHNPHGT 532

Query: 533 NITSPH 550
            + +PH
Sbjct: 533 -VVNPH 537



 Score = 71.2 bits (173), Expect = 3e-10
 Identities = 44/128 (34%), Positives = 64/128 (50%), Gaps = 15/128 (11%)
 Frame = +2

Query: 212 NPQSGVTNSHLNNLNMGSLHTAINNLHSGLSNPHSSVTNPH-----------NPHSSTHN 358
           NP   V N H +       H A+ N    ++NPH SV NPH           NPH S HN
Sbjct: 234 NPLESVVNIHESTHKS---HEAVVNPQESMNNPHGSVVNPHKSGHNPHGSVVNPHGSGHN 290

Query: 359 PYSSVTNP----HNPQSSITSSHFNINTNPHLSMGSPHSNVNNSSHLTMDSPRSNVDSSF 526
           P+ SV NP    HNP  S+ + H     NPH S+ +PH + +N  H ++ +P  +  +S+
Sbjct: 291 PHGSVVNPHESGHNPHGSVVNPH-ESGHNPHGSVVNPHESGHN-PHGSIVNPYESGHNSY 348

Query: 527 ATNITSPH 550
             ++ +PH
Sbjct: 349 G-SVVNPH 355



 Score = 70.9 bits (172), Expect = 4e-10
 Identities = 56/171 (32%), Positives = 71/171 (41%), Gaps = 25/171 (14%)
 Frame = +2

Query: 77  MNSPHSDVKLNIGSSHL---NVTNPYSNFGYXXXXXXXXXXXXXTGLHNPQSGVTNSHLN 247
           MN+PH  V     S H    +V NP+   G              +G HNP   V N H +
Sbjct: 260 MNNPHGSVVNPHKSGHNPHGSVVNPH---GSGHNPHGSVVNPHESG-HNPHGSVVNPHES 315

Query: 248 NLNMGSLHTAINNLHSGLSNPHSSVTNPH------------------NPHSSTHNPYSSV 373
             N    H ++ N H    NPH S+ NP+                  NPH S HNP+ SV
Sbjct: 316 GHNP---HGSVVNPHESGHNPHGSIVNPYESGHNSYGSVVNPHGSVVNPHGSGHNPHGSV 372

Query: 374 TNP----HNPQSSITSSHFNINTNPHLSMGSPHSNVNNSSHLTMDSPRSNV 514
            NP    HNP  SI + H     NPH S+  PH +V N  H +  +P   V
Sbjct: 373 VNPHESGHNPHGSIVNPH-GSGHNPHGSVVKPHGSVVN-PHESGHNPHGTV 421



 Score = 70.9 bits (172), Expect = 4e-10
 Identities = 48/146 (32%), Positives = 69/146 (47%), Gaps = 32/146 (21%)
 Frame = +2

Query: 209  HNPQSGVTNSHLNNLNM--------GSLHT----------AINNLHSGLSNPHSSVTNPH 334
            HNP + V N H++            GS H           + +N H  + NPH S  NPH
Sbjct: 877  HNPHNPVVNPHVSEHKSHDPVVHPHGSGHNKHEPIVNPIGSGHNSHGSVVNPHGSEHNPH 936

Query: 335  ----NPHSSTHNPYSSVTNP----HNPQSSITSSHFNINTNPHLSMGSPHSNVNN----- 475
                NPH S HNP+ SV NP    HNP  S+ ++H     N H S+ +PH + NN     
Sbjct: 937  GSVVNPHGSEHNPHGSVVNPHGSEHNPHGSVVNTH-GSGHNSHGSVANPHGSENNPHGSE 995

Query: 476  -SSHLTMDSPRSNVDSSFATNITSPH 550
             +SH ++ +P  +   +F  +I +PH
Sbjct: 996  HNSHGSVANPHGS-GHTFHGSIANPH 1020



 Score = 70.1 bits (170), Expect = 8e-10
 Identities = 50/155 (32%), Positives = 72/155 (46%), Gaps = 12/155 (7%)
 Frame = +2

Query: 122 HLNVTNPY----SNFGYXXXXXXXXXXXXXTGLHNPQSGVTNSHLNNLNMGSLHTAINNL 289
           H ++ NPY    +++G              +G HNP   V N H +  N    H +I N 
Sbjct: 334 HGSIVNPYESGHNSYGSVVNPHGSVVNPHGSG-HNPHGSVVNPHESGHNP---HGSIVNP 389

Query: 290 HSGLSNPHSSVTNPH----NPHSSTHNPYSSVTNP----HNPQSSITSSHFNINTNPHLS 445
           H    NPH SV  PH    NPH S HNP+ +V NP    HNP  SI +       NPH S
Sbjct: 390 HGSGHNPHGSVVKPHGSVVNPHESGHNPHGTVVNPHESGHNPHGSIVNP-LESGHNPHGS 448

Query: 446 MGSPHSNVNNSSHLTMDSPRSNVDSSFATNITSPH 550
           + +PH +  N  H ++ +P  +  +    ++ +PH
Sbjct: 449 VVNPHGSGLN-PHGSVVNPHESGHNPHG-SVVNPH 481



 Score = 68.9 bits (167), Expect = 2e-09
 Identities = 45/136 (33%), Positives = 65/136 (47%), Gaps = 21/136 (15%)
 Frame = +2

Query: 206 LHNPQSGVTNSHLNNLNMGSLHTAINNLHSGLSNPHSSVTNPH-----------NPHSST 352
           ++NP   V N H +  N    H ++ N H    NPH SV NPH           NPH S 
Sbjct: 260 MNNPHGSVVNPHKSGHNP---HGSVVNPHGSGHNPHGSVVNPHESGHNPHGSVVNPHESG 316

Query: 353 HNPYSSVTNP----HNPQSSITSSH------FNINTNPHLSMGSPHSNVNNSSHLTMDSP 502
           HNP+ SV NP    HNP  SI + +      +    NPH S+ +PH + +N  H ++ +P
Sbjct: 317 HNPHGSVVNPHESGHNPHGSIVNPYESGHNSYGSVVNPHGSVVNPHGSGHN-PHGSVVNP 375

Query: 503 RSNVDSSFATNITSPH 550
             +  +    +I +PH
Sbjct: 376 HESGHNPHG-SIVNPH 390



 Score = 68.9 bits (167), Expect = 2e-09
 Identities = 44/114 (38%), Positives = 58/114 (50%), Gaps = 25/114 (21%)
 Frame = +2

Query: 209 HNPQSGVTNSHLNNLNM-GSLHTAIN---NLHSGLSNPHSSVTNPH----NPHSSTHNPY 364
           HNP   V N H +  N  GS+   ++   N H  + NPH S  NPH    NPH S HNP+
Sbjct: 555 HNPHGTVVNPHESGHNPHGSIVNPLDSGHNPHGSVVNPHGSGLNPHGSVVNPHESGHNPH 614

Query: 365 SSVTNP----HNPQSSITSSHFN--------INT-----NPHLSMGSPHSNVNN 475
            SV NP    HNP  S+ +SH +        +NT     NPH S+ +PH + +N
Sbjct: 615 GSVVNPHESGHNPHGSVVNSHESGHNPHGSVVNTHESGHNPHGSVVNPHESGHN 668



 Score = 67.0 bits (162), Expect = 8e-09
 Identities = 43/129 (33%), Positives = 62/129 (48%), Gaps = 15/129 (11%)
 Frame = +2

Query: 209 HNPQSGVTNSHLNNLNMGSLHTAINNLHSGLSNPHSSVTNPH-----------NPHSSTH 355
           HNP   V N H +  N    H ++ N H    NPH +V NPH           NPH S H
Sbjct: 499 HNPHGSVVNPHESGHNP---HGSVVNPHESGHNPHGTVVNPHESGHNPHGSVVNPHESGH 555

Query: 356 NPYSSVTNP----HNPQSSITSSHFNINTNPHLSMGSPHSNVNNSSHLTMDSPRSNVDSS 523
           NP+ +V NP    HNP  SI +   +   NPH S+ +PH +  N  H ++ +P  +  + 
Sbjct: 556 NPHGTVVNPHESGHNPHGSIVNP-LDSGHNPHGSVVNPHGSGLN-PHGSVVNPHESGHNP 613

Query: 524 FATNITSPH 550
              ++ +PH
Sbjct: 614 HG-SVVNPH 621



 Score = 66.6 bits (161), Expect = 1e-08
 Identities = 52/181 (28%), Positives = 75/181 (41%), Gaps = 24/181 (13%)
 Frame = +2

Query: 80   NSPHSDVKLNIGS---SHLNVTNPYSNFGYXXXXXXXXXXXXXTGLHNPQSGVTNSHLNN 250
            ++PH  V    GS   SH +V NP+ +                   HN    V N H + 
Sbjct: 961  HNPHGSVVNTHGSGHNSHGSVANPHGSENNPHGSE-----------HNSHGSVANPHGSG 1009

Query: 251  LNMGSLHTAINNLHSGLSNPHSSVTNPH-----------NPHSSTHNPYSSVTNP----H 385
                + H +I N H    NPH SV NPH           NPH S HNP+ S  NP    H
Sbjct: 1010 ---HTFHGSIANPHVSAENPHGSVANPHGSEHNSHGSVANPHGSEHNPHGSEANPHGSEH 1066

Query: 386  NPQSSITSSHFNINTNPHLSMGSPHSNVNN------SSHLTMDSPRSNVDSSFATNITSP 547
            N   S+ + H      PH S  +PH +V N      ++H ++ +P  +  +    ++ +P
Sbjct: 1067 NSHGSVANPH-GSGHKPHGSEYNPHGSVANPLVSEYNTHGSVANPHGSAHNPHG-SVANP 1124

Query: 548  H 550
            H
Sbjct: 1125 H 1125



 Score = 66.2 bits (160), Expect = 2e-08
 Identities = 42/116 (36%), Positives = 54/116 (46%), Gaps = 15/116 (12%)
 Frame = +2

Query: 209 HNPQSGVTNSHLNNLNMGSLHTAINNLHSGLSNPHSSVTNPH-----------NPHSSTH 355
           HNP   V N H + LN    H ++ N H    NPH SV NPH           N H S H
Sbjct: 583 HNPHGSVVNPHGSGLNP---HGSVVNPHESGHNPHGSVVNPHESGHNPHGSVVNSHESGH 639

Query: 356 NPYSSVTNP----HNPQSSITSSHFNINTNPHLSMGSPHSNVNNSSHLTMDSPRSN 511
           NP+ SV N     HNP  S+ + H     NPH S+ + HS+    SH  + +P  +
Sbjct: 640 NPHGSVVNTHESGHNPHGSVVNPH-ESGHNPHGSVVNIHSS-EQKSHDPVGNPHGS 693



 Score = 57.8 bits (138), Expect = 1e-05
 Identities = 41/138 (29%), Positives = 62/138 (44%), Gaps = 7/138 (5%)
 Frame = +2

Query: 83   SPHSDVKLNIGS---SHLNVTNPYSNFGYXXXXXXXXXXXXXTGLHNPQSGVTNSHLNNL 253
            +PH  V+   GS   SH +V NP+ +                  + NP +   NSH +  
Sbjct: 1137 NPHGSVENPQGSAPNSHGSVANPHGS------------------VENPHASAHNSHGSVA 1178

Query: 254  NMGSLHTAINNLHSGLSNPHSSVTNPH----NPHSSTHNPYSSVTNPHNPQSSITSSHFN 421
            N    H + +N H  +++PH S  N H    NPH S HNP+ S    H P+      H +
Sbjct: 1179 NP---HGSAHNSHGSVASPHGSAHNSHGSGHNPHGSGHNPHESGHKTHGPRH---KPHGS 1232

Query: 422  INTNPHLSMGSPHSNVNN 475
            +   PH  M +PH +++N
Sbjct: 1233 V-VYPHEPMHNPHGHLHN 1249


>ref|XP_021324639.1| filaggrin-2-like isoform X3 [Danio rerio]
          Length = 1502

 Score = 74.7 bits (182), Expect = 2e-11
 Identities = 58/202 (28%), Positives = 84/202 (41%), Gaps = 39/202 (19%)
 Frame = +2

Query: 83   SPHSDVKLNIGS---SHLNVTNPYSNFGYXXXXXXXXXXXXXTGLHNPQSGVTNSHLNNL 253
            +PH  V    GS   SH +V NP+ +                   HNP     N H +  
Sbjct: 1028 NPHGSVANPHGSEHNSHGSVANPHGSE------------------HNPHGSEANPHGSEH 1069

Query: 254  NMGSLHTAINNLHSGLSNPHSSVTNPH------------------NPHSSTHNPYSSVTN 379
            N    H ++ N H     PH S  NPH                  NPH S HNP+ SV N
Sbjct: 1070 NS---HGSVANPHGSGHKPHGSEYNPHGSVANPLVSEYNTHGSVANPHGSAHNPHGSVAN 1126

Query: 380  PH------------------NPQSSITSSHFNINTNPHLSMGSPHSNVNNSSHLTMDSPR 505
            PH                  NPQ S  +SH ++  NPH S+ +PH++ +N SH ++ +P 
Sbjct: 1127 PHGSGHDPHGSEYNPHGSVENPQGSAPNSHGSV-ANPHGSVENPHASAHN-SHGSVANPH 1184

Query: 506  SNVDSSFATNITSPHSHLNSSY 571
             +  +S   ++ SPH   ++S+
Sbjct: 1185 GSAHNSHG-SVASPHGSAHNSH 1205



 Score = 72.4 bits (176), Expect = 1e-10
 Identities = 50/144 (34%), Positives = 66/144 (45%), Gaps = 29/144 (20%)
 Frame = +2

Query: 209 HNPQSGVTNSHLNNLNM-GSL----------HTAINNLHSGLSNPHSSVTNPH------- 334
           HNP   V N H + LN  GS+          H ++ N H    NPH SV NPH       
Sbjct: 446 HNPHGSVVNPHGSGLNPHGSVVNPHESGHNPHGSVVNPHESGHNPHGSVVNPHESGHNPH 505

Query: 335 ----NPHSSTHNPYSSVTNP----HNPQSSITSSHFNINTNPHLSMGSPHSNVNNSSHLT 490
               NPH S HNP+ SV NP    HNP  ++ + H     NPH S+ +PH + +N  H T
Sbjct: 506 GSVVNPHESGHNPHGSVVNPHESGHNPHGTVVNPH-ESGHNPHGSVVNPHESGHN-PHGT 563

Query: 491 MDSPRS---NVDSSFATNITSPHS 553
           + +P     N   S    + S H+
Sbjct: 564 VVNPHESGHNPHGSIVNPLDSGHN 587



 Score = 72.0 bits (175), Expect = 2e-10
 Identities = 46/126 (36%), Positives = 65/126 (51%), Gaps = 12/126 (9%)
 Frame = +2

Query: 209 HNPQSGVTNSHLNNLNM-GSLHTAI---NNLHSGLSNPHSSVTNPH----NPHSSTHNPY 364
           HNP   V N H +  N  GS+   +   +N H  + NPH S  NPH    NPH S HNP+
Sbjct: 418 HNPHGTVVNPHESGHNPHGSIVNPLESGHNPHGSVVNPHGSGLNPHGSVVNPHESGHNPH 477

Query: 365 SSVTNP----HNPQSSITSSHFNINTNPHLSMGSPHSNVNNSSHLTMDSPRSNVDSSFAT 532
            SV NP    HNP  S+ + H     NPH S+ +PH + +N  H ++ +P  +  +   T
Sbjct: 478 GSVVNPHESGHNPHGSVVNPH-ESGHNPHGSVVNPHESGHN-PHGSVVNPHESGHNPHGT 535

Query: 533 NITSPH 550
            + +PH
Sbjct: 536 -VVNPH 540



 Score = 70.9 bits (172), Expect = 4e-10
 Identities = 48/146 (32%), Positives = 69/146 (47%), Gaps = 32/146 (21%)
 Frame = +2

Query: 209  HNPQSGVTNSHLNNLNM--------GSLHT----------AINNLHSGLSNPHSSVTNPH 334
            HNP + V N H++            GS H           + +N H  + NPH S  NPH
Sbjct: 880  HNPHNPVVNPHVSEHKSHDPVVHPHGSGHNKHEPIVNPIGSGHNSHGSVVNPHGSEHNPH 939

Query: 335  ----NPHSSTHNPYSSVTNP----HNPQSSITSSHFNINTNPHLSMGSPHSNVNN----- 475
                NPH S HNP+ SV NP    HNP  S+ ++H     N H S+ +PH + NN     
Sbjct: 940  GSVVNPHGSEHNPHGSVVNPHGSEHNPHGSVVNTH-GSGHNSHGSVANPHGSENNPHGSE 998

Query: 476  -SSHLTMDSPRSNVDSSFATNITSPH 550
             +SH ++ +P  +   +F  +I +PH
Sbjct: 999  HNSHGSVANPHGS-GHTFHGSIANPH 1023



 Score = 69.7 bits (169), Expect = 1e-09
 Identities = 54/169 (31%), Positives = 74/169 (43%), Gaps = 11/169 (6%)
 Frame = +2

Query: 77  MNSPHSDVKLNIGSSHL---NVTNPYSNFGYXXXXXXXXXXXXXTGLHNPQSGVTNSHLN 247
           MN+PH  V     S H    +V NP+ +                   HNP   V N H +
Sbjct: 340 MNNPHGSVVNPHKSGHNPHGSVVNPHGSG------------------HNPHGSVVNPHES 381

Query: 248 NLNMGSLHTAINNLHSGLSNPHSSVTNPH----NPHSSTHNPYSSVTNP----HNPQSSI 403
             N    H +I N H    NPH SV  PH    NPH S HNP+ +V NP    HNP  SI
Sbjct: 382 GHNP---HGSIVNPHGSGHNPHGSVVKPHGSVVNPHESGHNPHGTVVNPHESGHNPHGSI 438

Query: 404 TSSHFNINTNPHLSMGSPHSNVNNSSHLTMDSPRSNVDSSFATNITSPH 550
            +       NPH S+ +PH +  N  H ++ +P  +  +    ++ +PH
Sbjct: 439 VNP-LESGHNPHGSVVNPHGSGLN-PHGSVVNPHESGHNPHG-SVVNPH 484



 Score = 68.9 bits (167), Expect = 2e-09
 Identities = 44/114 (38%), Positives = 58/114 (50%), Gaps = 25/114 (21%)
 Frame = +2

Query: 209 HNPQSGVTNSHLNNLNM-GSLHTAIN---NLHSGLSNPHSSVTNPH----NPHSSTHNPY 364
           HNP   V N H +  N  GS+   ++   N H  + NPH S  NPH    NPH S HNP+
Sbjct: 558 HNPHGTVVNPHESGHNPHGSIVNPLDSGHNPHGSVVNPHGSGLNPHGSVVNPHESGHNPH 617

Query: 365 SSVTNP----HNPQSSITSSHFN--------INT-----NPHLSMGSPHSNVNN 475
            SV NP    HNP  S+ +SH +        +NT     NPH S+ +PH + +N
Sbjct: 618 GSVVNPHESGHNPHGSVVNSHESGHNPHGSVVNTHESGHNPHGSVVNPHESGHN 671



 Score = 67.0 bits (162), Expect = 8e-09
 Identities = 43/129 (33%), Positives = 62/129 (48%), Gaps = 15/129 (11%)
 Frame = +2

Query: 209 HNPQSGVTNSHLNNLNMGSLHTAINNLHSGLSNPHSSVTNPH-----------NPHSSTH 355
           HNP   V N H +  N    H ++ N H    NPH +V NPH           NPH S H
Sbjct: 502 HNPHGSVVNPHESGHNP---HGSVVNPHESGHNPHGTVVNPHESGHNPHGSVVNPHESGH 558

Query: 356 NPYSSVTNP----HNPQSSITSSHFNINTNPHLSMGSPHSNVNNSSHLTMDSPRSNVDSS 523
           NP+ +V NP    HNP  SI +   +   NPH S+ +PH +  N  H ++ +P  +  + 
Sbjct: 559 NPHGTVVNPHESGHNPHGSIVNP-LDSGHNPHGSVVNPHGSGLN-PHGSVVNPHESGHNP 616

Query: 524 FATNITSPH 550
              ++ +PH
Sbjct: 617 HG-SVVNPH 624



 Score = 66.6 bits (161), Expect = 1e-08
 Identities = 37/102 (36%), Positives = 51/102 (50%), Gaps = 15/102 (14%)
 Frame = +2

Query: 254 NMGSLHTAINNLHSGLSNPHSSVTNPH-----------NPHSSTHNPYSSVTNP----HN 388
           +M + H ++ N H    NPH SV NPH           NPH S HNP+ S+ NP    HN
Sbjct: 339 SMNNPHGSVVNPHKSGHNPHGSVVNPHGSGHNPHGSVVNPHESGHNPHGSIVNPHGSGHN 398

Query: 389 PQSSITSSHFNINTNPHLSMGSPHSNVNNSSHLTMDSPRSNV 514
           P  S+   H ++  NPH S  +PH  V N  H +  +P  ++
Sbjct: 399 PHGSVVKPHGSV-VNPHESGHNPHGTVVN-PHESGHNPHGSI 438



 Score = 66.6 bits (161), Expect = 1e-08
 Identities = 52/181 (28%), Positives = 75/181 (41%), Gaps = 24/181 (13%)
 Frame = +2

Query: 80   NSPHSDVKLNIGS---SHLNVTNPYSNFGYXXXXXXXXXXXXXTGLHNPQSGVTNSHLNN 250
            ++PH  V    GS   SH +V NP+ +                   HN    V N H + 
Sbjct: 964  HNPHGSVVNTHGSGHNSHGSVANPHGSENNPHGSE-----------HNSHGSVANPHGSG 1012

Query: 251  LNMGSLHTAINNLHSGLSNPHSSVTNPH-----------NPHSSTHNPYSSVTNP----H 385
                + H +I N H    NPH SV NPH           NPH S HNP+ S  NP    H
Sbjct: 1013 ---HTFHGSIANPHVSAENPHGSVANPHGSEHNSHGSVANPHGSEHNPHGSEANPHGSEH 1069

Query: 386  NPQSSITSSHFNINTNPHLSMGSPHSNVNN------SSHLTMDSPRSNVDSSFATNITSP 547
            N   S+ + H      PH S  +PH +V N      ++H ++ +P  +  +    ++ +P
Sbjct: 1070 NSHGSVANPH-GSGHKPHGSEYNPHGSVANPLVSEYNTHGSVANPHGSAHNPHG-SVANP 1127

Query: 548  H 550
            H
Sbjct: 1128 H 1128



 Score = 66.2 bits (160), Expect = 2e-08
 Identities = 42/116 (36%), Positives = 54/116 (46%), Gaps = 15/116 (12%)
 Frame = +2

Query: 209 HNPQSGVTNSHLNNLNMGSLHTAINNLHSGLSNPHSSVTNPH-----------NPHSSTH 355
           HNP   V N H + LN    H ++ N H    NPH SV NPH           N H S H
Sbjct: 586 HNPHGSVVNPHGSGLNP---HGSVVNPHESGHNPHGSVVNPHESGHNPHGSVVNSHESGH 642

Query: 356 NPYSSVTNP----HNPQSSITSSHFNINTNPHLSMGSPHSNVNNSSHLTMDSPRSN 511
           NP+ SV N     HNP  S+ + H     NPH S+ + HS+    SH  + +P  +
Sbjct: 643 NPHGSVVNTHESGHNPHGSVVNPH-ESGHNPHGSVVNIHSS-EQKSHDPVGNPHGS 696



 Score = 63.9 bits (154), Expect = 9e-08
 Identities = 34/92 (36%), Positives = 50/92 (54%), Gaps = 8/92 (8%)
 Frame = +2

Query: 263 SLHTAINNLHSGLSNPHSSVTNPH----NPHSSTHNPYSSVTNP----HNPQSSITSSHF 418
           ++H + +  H  + NP  S+ NPH    NPH S HNP+ SV NP    HNP  S+ + H 
Sbjct: 321 NIHESTHKSHEAVVNPQESMNNPHGSVVNPHKSGHNPHGSVVNPHGSGHNPHGSVVNPH- 379

Query: 419 NINTNPHLSMGSPHSNVNNSSHLTMDSPRSNV 514
               NPH S+ +PH + +N  H ++  P  +V
Sbjct: 380 ESGHNPHGSIVNPHGSGHN-PHGSVVKPHGSV 410



 Score = 57.8 bits (138), Expect = 1e-05
 Identities = 41/138 (29%), Positives = 62/138 (44%), Gaps = 7/138 (5%)
 Frame = +2

Query: 83   SPHSDVKLNIGS---SHLNVTNPYSNFGYXXXXXXXXXXXXXTGLHNPQSGVTNSHLNNL 253
            +PH  V+   GS   SH +V NP+ +                  + NP +   NSH +  
Sbjct: 1140 NPHGSVENPQGSAPNSHGSVANPHGS------------------VENPHASAHNSHGSVA 1181

Query: 254  NMGSLHTAINNLHSGLSNPHSSVTNPH----NPHSSTHNPYSSVTNPHNPQSSITSSHFN 421
            N    H + +N H  +++PH S  N H    NPH S HNP+ S    H P+      H +
Sbjct: 1182 NP---HGSAHNSHGSVASPHGSAHNSHGSGHNPHGSGHNPHESGHKTHGPRH---KPHGS 1235

Query: 422  INTNPHLSMGSPHSNVNN 475
            +   PH  M +PH +++N
Sbjct: 1236 V-VYPHEPMHNPHGHLHN 1252


>ref|XP_009293378.1| filaggrin-2-like isoform X2 [Danio rerio]
          Length = 1520

 Score = 74.7 bits (182), Expect = 2e-11
 Identities = 58/202 (28%), Positives = 84/202 (41%), Gaps = 39/202 (19%)
 Frame = +2

Query: 83   SPHSDVKLNIGS---SHLNVTNPYSNFGYXXXXXXXXXXXXXTGLHNPQSGVTNSHLNNL 253
            +PH  V    GS   SH +V NP+ +                   HNP     N H +  
Sbjct: 1046 NPHGSVANPHGSEHNSHGSVANPHGSE------------------HNPHGSEANPHGSEH 1087

Query: 254  NMGSLHTAINNLHSGLSNPHSSVTNPH------------------NPHSSTHNPYSSVTN 379
            N    H ++ N H     PH S  NPH                  NPH S HNP+ SV N
Sbjct: 1088 NS---HGSVANPHGSGHKPHGSEYNPHGSVANPLVSEYNTHGSVANPHGSAHNPHGSVAN 1144

Query: 380  PH------------------NPQSSITSSHFNINTNPHLSMGSPHSNVNNSSHLTMDSPR 505
            PH                  NPQ S  +SH ++  NPH S+ +PH++ +N SH ++ +P 
Sbjct: 1145 PHGSGHDPHGSEYNPHGSVENPQGSAPNSHGSV-ANPHGSVENPHASAHN-SHGSVANPH 1202

Query: 506  SNVDSSFATNITSPHSHLNSSY 571
             +  +S   ++ SPH   ++S+
Sbjct: 1203 GSAHNSHG-SVASPHGSAHNSH 1223



 Score = 72.4 bits (176), Expect = 1e-10
 Identities = 50/144 (34%), Positives = 66/144 (45%), Gaps = 29/144 (20%)
 Frame = +2

Query: 209 HNPQSGVTNSHLNNLNM-GSL----------HTAINNLHSGLSNPHSSVTNPH------- 334
           HNP   V N H + LN  GS+          H ++ N H    NPH SV NPH       
Sbjct: 464 HNPHGSVVNPHGSGLNPHGSVVNPHESGHNPHGSVVNPHESGHNPHGSVVNPHESGHNPH 523

Query: 335 ----NPHSSTHNPYSSVTNP----HNPQSSITSSHFNINTNPHLSMGSPHSNVNNSSHLT 490
               NPH S HNP+ SV NP    HNP  ++ + H     NPH S+ +PH + +N  H T
Sbjct: 524 GSVVNPHESGHNPHGSVVNPHESGHNPHGTVVNPH-ESGHNPHGSVVNPHESGHN-PHGT 581

Query: 491 MDSPRS---NVDSSFATNITSPHS 553
           + +P     N   S    + S H+
Sbjct: 582 VVNPHESGHNPHGSIVNPLDSGHN 605



 Score = 72.0 bits (175), Expect = 2e-10
 Identities = 46/126 (36%), Positives = 65/126 (51%), Gaps = 12/126 (9%)
 Frame = +2

Query: 209 HNPQSGVTNSHLNNLNM-GSLHTAI---NNLHSGLSNPHSSVTNPH----NPHSSTHNPY 364
           HNP   V N H +  N  GS+   +   +N H  + NPH S  NPH    NPH S HNP+
Sbjct: 436 HNPHGTVVNPHESGHNPHGSIVNPLESGHNPHGSVVNPHGSGLNPHGSVVNPHESGHNPH 495

Query: 365 SSVTNP----HNPQSSITSSHFNINTNPHLSMGSPHSNVNNSSHLTMDSPRSNVDSSFAT 532
            SV NP    HNP  S+ + H     NPH S+ +PH + +N  H ++ +P  +  +   T
Sbjct: 496 GSVVNPHESGHNPHGSVVNPH-ESGHNPHGSVVNPHESGHN-PHGSVVNPHESGHNPHGT 553

Query: 533 NITSPH 550
            + +PH
Sbjct: 554 -VVNPH 558



 Score = 71.2 bits (173), Expect = 3e-10
 Identities = 44/128 (34%), Positives = 64/128 (50%), Gaps = 15/128 (11%)
 Frame = +2

Query: 212 NPQSGVTNSHLNNLNMGSLHTAINNLHSGLSNPHSSVTNPH-----------NPHSSTHN 358
           NP   V N H +       H A+ N    ++NPH SV NPH           NPH S HN
Sbjct: 255 NPLESVVNIHESTHKS---HEAVVNPQESMNNPHGSVVNPHKSGHNPHGSVVNPHGSGHN 311

Query: 359 PYSSVTNP----HNPQSSITSSHFNINTNPHLSMGSPHSNVNNSSHLTMDSPRSNVDSSF 526
           P+ SV NP    HNP  S+ + H     NPH S+ +PH + +N  H ++ +P  +  +S+
Sbjct: 312 PHGSVVNPHESGHNPHGSVVNPH-ESGHNPHGSVVNPHESGHN-PHGSIVNPYESGHNSY 369

Query: 527 ATNITSPH 550
             ++ +PH
Sbjct: 370 G-SVVNPH 376



 Score = 70.9 bits (172), Expect = 4e-10
 Identities = 56/171 (32%), Positives = 71/171 (41%), Gaps = 25/171 (14%)
 Frame = +2

Query: 77  MNSPHSDVKLNIGSSHL---NVTNPYSNFGYXXXXXXXXXXXXXTGLHNPQSGVTNSHLN 247
           MN+PH  V     S H    +V NP+   G              +G HNP   V N H +
Sbjct: 281 MNNPHGSVVNPHKSGHNPHGSVVNPH---GSGHNPHGSVVNPHESG-HNPHGSVVNPHES 336

Query: 248 NLNMGSLHTAINNLHSGLSNPHSSVTNPH------------------NPHSSTHNPYSSV 373
             N    H ++ N H    NPH S+ NP+                  NPH S HNP+ SV
Sbjct: 337 GHNP---HGSVVNPHESGHNPHGSIVNPYESGHNSYGSVVNPHGSVVNPHGSGHNPHGSV 393

Query: 374 TNP----HNPQSSITSSHFNINTNPHLSMGSPHSNVNNSSHLTMDSPRSNV 514
            NP    HNP  SI + H     NPH S+  PH +V N  H +  +P   V
Sbjct: 394 VNPHESGHNPHGSIVNPH-GSGHNPHGSVVKPHGSVVN-PHESGHNPHGTV 442



 Score = 70.9 bits (172), Expect = 4e-10
 Identities = 48/146 (32%), Positives = 69/146 (47%), Gaps = 32/146 (21%)
 Frame = +2

Query: 209  HNPQSGVTNSHLNNLNM--------GSLHT----------AINNLHSGLSNPHSSVTNPH 334
            HNP + V N H++            GS H           + +N H  + NPH S  NPH
Sbjct: 898  HNPHNPVVNPHVSEHKSHDPVVHPHGSGHNKHEPIVNPIGSGHNSHGSVVNPHGSEHNPH 957

Query: 335  ----NPHSSTHNPYSSVTNP----HNPQSSITSSHFNINTNPHLSMGSPHSNVNN----- 475
                NPH S HNP+ SV NP    HNP  S+ ++H     N H S+ +PH + NN     
Sbjct: 958  GSVVNPHGSEHNPHGSVVNPHGSEHNPHGSVVNTH-GSGHNSHGSVANPHGSENNPHGSE 1016

Query: 476  -SSHLTMDSPRSNVDSSFATNITSPH 550
             +SH ++ +P  +   +F  +I +PH
Sbjct: 1017 HNSHGSVANPHGS-GHTFHGSIANPH 1041



 Score = 70.1 bits (170), Expect = 8e-10
 Identities = 50/155 (32%), Positives = 72/155 (46%), Gaps = 12/155 (7%)
 Frame = +2

Query: 122 HLNVTNPY----SNFGYXXXXXXXXXXXXXTGLHNPQSGVTNSHLNNLNMGSLHTAINNL 289
           H ++ NPY    +++G              +G HNP   V N H +  N    H +I N 
Sbjct: 355 HGSIVNPYESGHNSYGSVVNPHGSVVNPHGSG-HNPHGSVVNPHESGHNP---HGSIVNP 410

Query: 290 HSGLSNPHSSVTNPH----NPHSSTHNPYSSVTNP----HNPQSSITSSHFNINTNPHLS 445
           H    NPH SV  PH    NPH S HNP+ +V NP    HNP  SI +       NPH S
Sbjct: 411 HGSGHNPHGSVVKPHGSVVNPHESGHNPHGTVVNPHESGHNPHGSIVNP-LESGHNPHGS 469

Query: 446 MGSPHSNVNNSSHLTMDSPRSNVDSSFATNITSPH 550
           + +PH +  N  H ++ +P  +  +    ++ +PH
Sbjct: 470 VVNPHGSGLN-PHGSVVNPHESGHNPHG-SVVNPH 502



 Score = 68.9 bits (167), Expect = 2e-09
 Identities = 45/136 (33%), Positives = 65/136 (47%), Gaps = 21/136 (15%)
 Frame = +2

Query: 206 LHNPQSGVTNSHLNNLNMGSLHTAINNLHSGLSNPHSSVTNPH-----------NPHSST 352
           ++NP   V N H +  N    H ++ N H    NPH SV NPH           NPH S 
Sbjct: 281 MNNPHGSVVNPHKSGHNP---HGSVVNPHGSGHNPHGSVVNPHESGHNPHGSVVNPHESG 337

Query: 353 HNPYSSVTNP----HNPQSSITSSH------FNINTNPHLSMGSPHSNVNNSSHLTMDSP 502
           HNP+ SV NP    HNP  SI + +      +    NPH S+ +PH + +N  H ++ +P
Sbjct: 338 HNPHGSVVNPHESGHNPHGSIVNPYESGHNSYGSVVNPHGSVVNPHGSGHN-PHGSVVNP 396

Query: 503 RSNVDSSFATNITSPH 550
             +  +    +I +PH
Sbjct: 397 HESGHNPHG-SIVNPH 411



 Score = 68.9 bits (167), Expect = 2e-09
 Identities = 44/114 (38%), Positives = 58/114 (50%), Gaps = 25/114 (21%)
 Frame = +2

Query: 209 HNPQSGVTNSHLNNLNM-GSLHTAIN---NLHSGLSNPHSSVTNPH----NPHSSTHNPY 364
           HNP   V N H +  N  GS+   ++   N H  + NPH S  NPH    NPH S HNP+
Sbjct: 576 HNPHGTVVNPHESGHNPHGSIVNPLDSGHNPHGSVVNPHGSGLNPHGSVVNPHESGHNPH 635

Query: 365 SSVTNP----HNPQSSITSSHFN--------INT-----NPHLSMGSPHSNVNN 475
            SV NP    HNP  S+ +SH +        +NT     NPH S+ +PH + +N
Sbjct: 636 GSVVNPHESGHNPHGSVVNSHESGHNPHGSVVNTHESGHNPHGSVVNPHESGHN 689



 Score = 67.0 bits (162), Expect = 8e-09
 Identities = 43/129 (33%), Positives = 62/129 (48%), Gaps = 15/129 (11%)
 Frame = +2

Query: 209 HNPQSGVTNSHLNNLNMGSLHTAINNLHSGLSNPHSSVTNPH-----------NPHSSTH 355
           HNP   V N H +  N    H ++ N H    NPH +V NPH           NPH S H
Sbjct: 520 HNPHGSVVNPHESGHNP---HGSVVNPHESGHNPHGTVVNPHESGHNPHGSVVNPHESGH 576

Query: 356 NPYSSVTNP----HNPQSSITSSHFNINTNPHLSMGSPHSNVNNSSHLTMDSPRSNVDSS 523
           NP+ +V NP    HNP  SI +   +   NPH S+ +PH +  N  H ++ +P  +  + 
Sbjct: 577 NPHGTVVNPHESGHNPHGSIVNP-LDSGHNPHGSVVNPHGSGLN-PHGSVVNPHESGHNP 634

Query: 524 FATNITSPH 550
              ++ +PH
Sbjct: 635 HG-SVVNPH 642



 Score = 66.6 bits (161), Expect = 1e-08
 Identities = 52/181 (28%), Positives = 75/181 (41%), Gaps = 24/181 (13%)
 Frame = +2

Query: 80   NSPHSDVKLNIGS---SHLNVTNPYSNFGYXXXXXXXXXXXXXTGLHNPQSGVTNSHLNN 250
            ++PH  V    GS   SH +V NP+ +                   HN    V N H + 
Sbjct: 982  HNPHGSVVNTHGSGHNSHGSVANPHGSENNPHGSE-----------HNSHGSVANPHGSG 1030

Query: 251  LNMGSLHTAINNLHSGLSNPHSSVTNPH-----------NPHSSTHNPYSSVTNP----H 385
                + H +I N H    NPH SV NPH           NPH S HNP+ S  NP    H
Sbjct: 1031 ---HTFHGSIANPHVSAENPHGSVANPHGSEHNSHGSVANPHGSEHNPHGSEANPHGSEH 1087

Query: 386  NPQSSITSSHFNINTNPHLSMGSPHSNVNN------SSHLTMDSPRSNVDSSFATNITSP 547
            N   S+ + H      PH S  +PH +V N      ++H ++ +P  +  +    ++ +P
Sbjct: 1088 NSHGSVANPH-GSGHKPHGSEYNPHGSVANPLVSEYNTHGSVANPHGSAHNPHG-SVANP 1145

Query: 548  H 550
            H
Sbjct: 1146 H 1146



 Score = 66.2 bits (160), Expect = 2e-08
 Identities = 42/116 (36%), Positives = 54/116 (46%), Gaps = 15/116 (12%)
 Frame = +2

Query: 209 HNPQSGVTNSHLNNLNMGSLHTAINNLHSGLSNPHSSVTNPH-----------NPHSSTH 355
           HNP   V N H + LN    H ++ N H    NPH SV NPH           N H S H
Sbjct: 604 HNPHGSVVNPHGSGLNP---HGSVVNPHESGHNPHGSVVNPHESGHNPHGSVVNSHESGH 660

Query: 356 NPYSSVTNP----HNPQSSITSSHFNINTNPHLSMGSPHSNVNNSSHLTMDSPRSN 511
           NP+ SV N     HNP  S+ + H     NPH S+ + HS+    SH  + +P  +
Sbjct: 661 NPHGSVVNTHESGHNPHGSVVNPH-ESGHNPHGSVVNIHSS-EQKSHDPVGNPHGS 714



 Score = 57.8 bits (138), Expect = 1e-05
 Identities = 41/138 (29%), Positives = 62/138 (44%), Gaps = 7/138 (5%)
 Frame = +2

Query: 83   SPHSDVKLNIGS---SHLNVTNPYSNFGYXXXXXXXXXXXXXTGLHNPQSGVTNSHLNNL 253
            +PH  V+   GS   SH +V NP+ +                  + NP +   NSH +  
Sbjct: 1158 NPHGSVENPQGSAPNSHGSVANPHGS------------------VENPHASAHNSHGSVA 1199

Query: 254  NMGSLHTAINNLHSGLSNPHSSVTNPH----NPHSSTHNPYSSVTNPHNPQSSITSSHFN 421
            N    H + +N H  +++PH S  N H    NPH S HNP+ S    H P+      H +
Sbjct: 1200 NP---HGSAHNSHGSVASPHGSAHNSHGSGHNPHGSGHNPHESGHKTHGPRH---KPHGS 1253

Query: 422  INTNPHLSMGSPHSNVNN 475
            +   PH  M +PH +++N
Sbjct: 1254 V-VYPHEPMHNPHGHLHN 1270


>ref|XP_009293374.1| filaggrin-2-like isoform X1 [Danio rerio]
          Length = 1579

 Score = 74.7 bits (182), Expect = 2e-11
 Identities = 58/202 (28%), Positives = 84/202 (41%), Gaps = 39/202 (19%)
 Frame = +2

Query: 83   SPHSDVKLNIGS---SHLNVTNPYSNFGYXXXXXXXXXXXXXTGLHNPQSGVTNSHLNNL 253
            +PH  V    GS   SH +V NP+ +                   HNP     N H +  
Sbjct: 1105 NPHGSVANPHGSEHNSHGSVANPHGSE------------------HNPHGSEANPHGSEH 1146

Query: 254  NMGSLHTAINNLHSGLSNPHSSVTNPH------------------NPHSSTHNPYSSVTN 379
            N    H ++ N H     PH S  NPH                  NPH S HNP+ SV N
Sbjct: 1147 NS---HGSVANPHGSGHKPHGSEYNPHGSVANPLVSEYNTHGSVANPHGSAHNPHGSVAN 1203

Query: 380  PH------------------NPQSSITSSHFNINTNPHLSMGSPHSNVNNSSHLTMDSPR 505
            PH                  NPQ S  +SH ++  NPH S+ +PH++ +N SH ++ +P 
Sbjct: 1204 PHGSGHDPHGSEYNPHGSVENPQGSAPNSHGSV-ANPHGSVENPHASAHN-SHGSVANPH 1261

Query: 506  SNVDSSFATNITSPHSHLNSSY 571
             +  +S   ++ SPH   ++S+
Sbjct: 1262 GSAHNSHG-SVASPHGSAHNSH 1282



 Score = 72.4 bits (176), Expect = 1e-10
 Identities = 50/144 (34%), Positives = 66/144 (45%), Gaps = 29/144 (20%)
 Frame = +2

Query: 209 HNPQSGVTNSHLNNLNM-GSL----------HTAINNLHSGLSNPHSSVTNPH------- 334
           HNP   V N H + LN  GS+          H ++ N H    NPH SV NPH       
Sbjct: 523 HNPHGSVVNPHGSGLNPHGSVVNPHESGHNPHGSVVNPHESGHNPHGSVVNPHESGHNPH 582

Query: 335 ----NPHSSTHNPYSSVTNP----HNPQSSITSSHFNINTNPHLSMGSPHSNVNNSSHLT 490
               NPH S HNP+ SV NP    HNP  ++ + H     NPH S+ +PH + +N  H T
Sbjct: 583 GSVVNPHESGHNPHGSVVNPHESGHNPHGTVVNPH-ESGHNPHGSVVNPHESGHN-PHGT 640

Query: 491 MDSPRS---NVDSSFATNITSPHS 553
           + +P     N   S    + S H+
Sbjct: 641 VVNPHESGHNPHGSIVNPLDSGHN 664



 Score = 72.0 bits (175), Expect = 2e-10
 Identities = 46/126 (36%), Positives = 65/126 (51%), Gaps = 12/126 (9%)
 Frame = +2

Query: 209 HNPQSGVTNSHLNNLNM-GSLHTAI---NNLHSGLSNPHSSVTNPH----NPHSSTHNPY 364
           HNP   V N H +  N  GS+   +   +N H  + NPH S  NPH    NPH S HNP+
Sbjct: 495 HNPHGTVVNPHESGHNPHGSIVNPLESGHNPHGSVVNPHGSGLNPHGSVVNPHESGHNPH 554

Query: 365 SSVTNP----HNPQSSITSSHFNINTNPHLSMGSPHSNVNNSSHLTMDSPRSNVDSSFAT 532
            SV NP    HNP  S+ + H     NPH S+ +PH + +N  H ++ +P  +  +   T
Sbjct: 555 GSVVNPHESGHNPHGSVVNPH-ESGHNPHGSVVNPHESGHN-PHGSVVNPHESGHNPHGT 612

Query: 533 NITSPH 550
            + +PH
Sbjct: 613 -VVNPH 617



 Score = 71.2 bits (173), Expect = 3e-10
 Identities = 44/128 (34%), Positives = 64/128 (50%), Gaps = 15/128 (11%)
 Frame = +2

Query: 212 NPQSGVTNSHLNNLNMGSLHTAINNLHSGLSNPHSSVTNPH-----------NPHSSTHN 358
           NP   V N H +       H A+ N    ++NPH SV NPH           NPH S HN
Sbjct: 314 NPLESVVNIHESTHKS---HEAVVNPQESMNNPHGSVVNPHKSGHNPHGSVVNPHGSGHN 370

Query: 359 PYSSVTNP----HNPQSSITSSHFNINTNPHLSMGSPHSNVNNSSHLTMDSPRSNVDSSF 526
           P+ SV NP    HNP  S+ + H     NPH S+ +PH + +N  H ++ +P  +  +S+
Sbjct: 371 PHGSVVNPHESGHNPHGSVVNPH-ESGHNPHGSVVNPHESGHN-PHGSIVNPYESGHNSY 428

Query: 527 ATNITSPH 550
             ++ +PH
Sbjct: 429 G-SVVNPH 435



 Score = 70.9 bits (172), Expect = 4e-10
 Identities = 56/171 (32%), Positives = 71/171 (41%), Gaps = 25/171 (14%)
 Frame = +2

Query: 77  MNSPHSDVKLNIGSSHL---NVTNPYSNFGYXXXXXXXXXXXXXTGLHNPQSGVTNSHLN 247
           MN+PH  V     S H    +V NP+   G              +G HNP   V N H +
Sbjct: 340 MNNPHGSVVNPHKSGHNPHGSVVNPH---GSGHNPHGSVVNPHESG-HNPHGSVVNPHES 395

Query: 248 NLNMGSLHTAINNLHSGLSNPHSSVTNPH------------------NPHSSTHNPYSSV 373
             N    H ++ N H    NPH S+ NP+                  NPH S HNP+ SV
Sbjct: 396 GHNP---HGSVVNPHESGHNPHGSIVNPYESGHNSYGSVVNPHGSVVNPHGSGHNPHGSV 452

Query: 374 TNP----HNPQSSITSSHFNINTNPHLSMGSPHSNVNNSSHLTMDSPRSNV 514
            NP    HNP  SI + H     NPH S+  PH +V N  H +  +P   V
Sbjct: 453 VNPHESGHNPHGSIVNPH-GSGHNPHGSVVKPHGSVVN-PHESGHNPHGTV 501



 Score = 70.9 bits (172), Expect = 4e-10
 Identities = 48/146 (32%), Positives = 69/146 (47%), Gaps = 32/146 (21%)
 Frame = +2

Query: 209  HNPQSGVTNSHLNNLNM--------GSLHT----------AINNLHSGLSNPHSSVTNPH 334
            HNP + V N H++            GS H           + +N H  + NPH S  NPH
Sbjct: 957  HNPHNPVVNPHVSEHKSHDPVVHPHGSGHNKHEPIVNPIGSGHNSHGSVVNPHGSEHNPH 1016

Query: 335  ----NPHSSTHNPYSSVTNP----HNPQSSITSSHFNINTNPHLSMGSPHSNVNN----- 475
                NPH S HNP+ SV NP    HNP  S+ ++H     N H S+ +PH + NN     
Sbjct: 1017 GSVVNPHGSEHNPHGSVVNPHGSEHNPHGSVVNTH-GSGHNSHGSVANPHGSENNPHGSE 1075

Query: 476  -SSHLTMDSPRSNVDSSFATNITSPH 550
             +SH ++ +P  +   +F  +I +PH
Sbjct: 1076 HNSHGSVANPHGS-GHTFHGSIANPH 1100



 Score = 70.1 bits (170), Expect = 8e-10
 Identities = 50/155 (32%), Positives = 72/155 (46%), Gaps = 12/155 (7%)
 Frame = +2

Query: 122 HLNVTNPY----SNFGYXXXXXXXXXXXXXTGLHNPQSGVTNSHLNNLNMGSLHTAINNL 289
           H ++ NPY    +++G              +G HNP   V N H +  N    H +I N 
Sbjct: 414 HGSIVNPYESGHNSYGSVVNPHGSVVNPHGSG-HNPHGSVVNPHESGHNP---HGSIVNP 469

Query: 290 HSGLSNPHSSVTNPH----NPHSSTHNPYSSVTNP----HNPQSSITSSHFNINTNPHLS 445
           H    NPH SV  PH    NPH S HNP+ +V NP    HNP  SI +       NPH S
Sbjct: 470 HGSGHNPHGSVVKPHGSVVNPHESGHNPHGTVVNPHESGHNPHGSIVNP-LESGHNPHGS 528

Query: 446 MGSPHSNVNNSSHLTMDSPRSNVDSSFATNITSPH 550
           + +PH +  N  H ++ +P  +  +    ++ +PH
Sbjct: 529 VVNPHGSGLN-PHGSVVNPHESGHNPHG-SVVNPH 561



 Score = 68.9 bits (167), Expect = 2e-09
 Identities = 45/136 (33%), Positives = 65/136 (47%), Gaps = 21/136 (15%)
 Frame = +2

Query: 206 LHNPQSGVTNSHLNNLNMGSLHTAINNLHSGLSNPHSSVTNPH-----------NPHSST 352
           ++NP   V N H +  N    H ++ N H    NPH SV NPH           NPH S 
Sbjct: 340 MNNPHGSVVNPHKSGHNP---HGSVVNPHGSGHNPHGSVVNPHESGHNPHGSVVNPHESG 396

Query: 353 HNPYSSVTNP----HNPQSSITSSH------FNINTNPHLSMGSPHSNVNNSSHLTMDSP 502
           HNP+ SV NP    HNP  SI + +      +    NPH S+ +PH + +N  H ++ +P
Sbjct: 397 HNPHGSVVNPHESGHNPHGSIVNPYESGHNSYGSVVNPHGSVVNPHGSGHN-PHGSVVNP 455

Query: 503 RSNVDSSFATNITSPH 550
             +  +    +I +PH
Sbjct: 456 HESGHNPHG-SIVNPH 470



 Score = 68.9 bits (167), Expect = 2e-09
 Identities = 44/114 (38%), Positives = 58/114 (50%), Gaps = 25/114 (21%)
 Frame = +2

Query: 209 HNPQSGVTNSHLNNLNM-GSLHTAIN---NLHSGLSNPHSSVTNPH----NPHSSTHNPY 364
           HNP   V N H +  N  GS+   ++   N H  + NPH S  NPH    NPH S HNP+
Sbjct: 635 HNPHGTVVNPHESGHNPHGSIVNPLDSGHNPHGSVVNPHGSGLNPHGSVVNPHESGHNPH 694

Query: 365 SSVTNP----HNPQSSITSSHFN--------INT-----NPHLSMGSPHSNVNN 475
            SV NP    HNP  S+ +SH +        +NT     NPH S+ +PH + +N
Sbjct: 695 GSVVNPHESGHNPHGSVVNSHESGHNPHGSVVNTHESGHNPHGSVVNPHESGHN 748



 Score = 67.0 bits (162), Expect = 8e-09
 Identities = 43/129 (33%), Positives = 62/129 (48%), Gaps = 15/129 (11%)
 Frame = +2

Query: 209 HNPQSGVTNSHLNNLNMGSLHTAINNLHSGLSNPHSSVTNPH-----------NPHSSTH 355
           HNP   V N H +  N    H ++ N H    NPH +V NPH           NPH S H
Sbjct: 579 HNPHGSVVNPHESGHNP---HGSVVNPHESGHNPHGTVVNPHESGHNPHGSVVNPHESGH 635

Query: 356 NPYSSVTNP----HNPQSSITSSHFNINTNPHLSMGSPHSNVNNSSHLTMDSPRSNVDSS 523
           NP+ +V NP    HNP  SI +   +   NPH S+ +PH +  N  H ++ +P  +  + 
Sbjct: 636 NPHGTVVNPHESGHNPHGSIVNP-LDSGHNPHGSVVNPHGSGLN-PHGSVVNPHESGHNP 693

Query: 524 FATNITSPH 550
              ++ +PH
Sbjct: 694 HG-SVVNPH 701



 Score = 66.6 bits (161), Expect = 1e-08
 Identities = 52/181 (28%), Positives = 75/181 (41%), Gaps = 24/181 (13%)
 Frame = +2

Query: 80   NSPHSDVKLNIGS---SHLNVTNPYSNFGYXXXXXXXXXXXXXTGLHNPQSGVTNSHLNN 250
            ++PH  V    GS   SH +V NP+ +                   HN    V N H + 
Sbjct: 1041 HNPHGSVVNTHGSGHNSHGSVANPHGSENNPHGSE-----------HNSHGSVANPHGSG 1089

Query: 251  LNMGSLHTAINNLHSGLSNPHSSVTNPH-----------NPHSSTHNPYSSVTNP----H 385
                + H +I N H    NPH SV NPH           NPH S HNP+ S  NP    H
Sbjct: 1090 ---HTFHGSIANPHVSAENPHGSVANPHGSEHNSHGSVANPHGSEHNPHGSEANPHGSEH 1146

Query: 386  NPQSSITSSHFNINTNPHLSMGSPHSNVNN------SSHLTMDSPRSNVDSSFATNITSP 547
            N   S+ + H      PH S  +PH +V N      ++H ++ +P  +  +    ++ +P
Sbjct: 1147 NSHGSVANPH-GSGHKPHGSEYNPHGSVANPLVSEYNTHGSVANPHGSAHNPHG-SVANP 1204

Query: 548  H 550
            H
Sbjct: 1205 H 1205



 Score = 66.2 bits (160), Expect = 2e-08
 Identities = 42/116 (36%), Positives = 54/116 (46%), Gaps = 15/116 (12%)
 Frame = +2

Query: 209 HNPQSGVTNSHLNNLNMGSLHTAINNLHSGLSNPHSSVTNPH-----------NPHSSTH 355
           HNP   V N H + LN    H ++ N H    NPH SV NPH           N H S H
Sbjct: 663 HNPHGSVVNPHGSGLNP---HGSVVNPHESGHNPHGSVVNPHESGHNPHGSVVNSHESGH 719

Query: 356 NPYSSVTNP----HNPQSSITSSHFNINTNPHLSMGSPHSNVNNSSHLTMDSPRSN 511
           NP+ SV N     HNP  S+ + H     NPH S+ + HS+    SH  + +P  +
Sbjct: 720 NPHGSVVNTHESGHNPHGSVVNPH-ESGHNPHGSVVNIHSS-EQKSHDPVGNPHGS 773



 Score = 57.8 bits (138), Expect = 1e-05
 Identities = 41/138 (29%), Positives = 62/138 (44%), Gaps = 7/138 (5%)
 Frame = +2

Query: 83   SPHSDVKLNIGS---SHLNVTNPYSNFGYXXXXXXXXXXXXXTGLHNPQSGVTNSHLNNL 253
            +PH  V+   GS   SH +V NP+ +                  + NP +   NSH +  
Sbjct: 1217 NPHGSVENPQGSAPNSHGSVANPHGS------------------VENPHASAHNSHGSVA 1258

Query: 254  NMGSLHTAINNLHSGLSNPHSSVTNPH----NPHSSTHNPYSSVTNPHNPQSSITSSHFN 421
            N    H + +N H  +++PH S  N H    NPH S HNP+ S    H P+      H +
Sbjct: 1259 NP---HGSAHNSHGSVASPHGSAHNSHGSGHNPHGSGHNPHESGHKTHGPRH---KPHGS 1312

Query: 422  INTNPHLSMGSPHSNVNN 475
            +   PH  M +PH +++N
Sbjct: 1313 V-VYPHEPMHNPHGHLHN 1329


>ref|XP_014040269.1| PREDICTED: TBC1 domain family member 30-like, partial [Salmo salar]
          Length = 1149

 Score = 66.6 bits (161), Expect = 1e-08
 Identities = 60/176 (34%), Positives = 92/176 (52%), Gaps = 12/176 (6%)
 Frame = +2

Query: 77   MNSPHSDVKLNIGSSHLNVTNPYSNFGYXXXXXXXXXXXXXTGLHNPQSGVTNSHLNNLN 256
            +++PHS V L+   S + ++NP+S                   L NP S VT   L+N +
Sbjct: 978  LSNPHSPVTLSNPHSPVTLSNPHS-------PVTLSNPHSPVTLSNPHSPVT---LSNPH 1027

Query: 257  MGSLHTAINNLHS--GLSNPHSSVT--NPHNPHSSTHNPYSSVT--NPHNPQSSITSSHF 418
                   ++N HS   LSNPHS VT  NPH+P + + NP+S VT  NPH+P  ++++ H 
Sbjct: 1028 SPHSPVTLSNPHSPVTLSNPHSPVTLSNPHSPVTPS-NPHSPVTLSNPHSP-VTLSNPHS 1085

Query: 419  NIN-TNPH--LSMGSPHSNV---NNSSHLTMDSPRSNVDSSFATNITSPHSHLNSS 568
             +  +NPH  +++ +PHS V   N  S +T+ +P S V  S      +PHS +  S
Sbjct: 1086 PVTLSNPHSPVTLSNPHSPVTLSNPHSPVTLSNPHSPVTPS------NPHSPVTPS 1135


>ref|XP_015198316.1| PREDICTED: mucin-2 [Lepisosteus oculatus]
          Length = 261

 Score = 64.7 bits (156), Expect = 2e-08
 Identities = 48/165 (29%), Positives = 78/165 (47%)
 Frame = +2

Query: 77  MNSPHSDVKLNIGSSHLNVTNPYSNFGYXXXXXXXXXXXXXTGLHNPQSGVTNSHLNNLN 256
           +  PH+ +     SSH  +T P++                 T L +PQ+ +T+SH     
Sbjct: 99  LTGPHTPLT----SSHTALTGPHTAL-----------TGPHTPLTSPQTALTSSH----- 138

Query: 257 MGSLHTAINNLHSGLSNPHSSVTNPHNPHSSTHNPYSSVTNPHNPQSSITSSHFNINTNP 436
                TA+   H+ L +PH  +T PH   +S+  P +S      PQS++TSSH  + T P
Sbjct: 139 -----TALTGPHTALMSPHIVLTGPHKALTSSQTPLTS------PQSALTSSHTAL-TGP 186

Query: 437 HLSMGSPHSNVNNSSHLTMDSPRSNVDSSFATNITSPHSHLNSSY 571
           H +  SPH+ +    H  +  P++ + SS  T +T PH+ L   +
Sbjct: 187 HTAPTSPHTPL-TGPHTALTGPQTPLTSSH-TALTGPHTPLTGPH 229



 Score = 62.4 bits (150), Expect = 1e-07
 Identities = 44/139 (31%), Positives = 71/139 (51%), Gaps = 21/139 (15%)
 Frame = +2

Query: 200 TGLHNPQSGVTNSHLNNLNMGSLHTAINNLHSGLSNPHSSV-------TNPHNPHSSTHN 358
           TG H P +G   +      +   HTA+    + L+ PH+++       T PH P +S+H 
Sbjct: 58  TGPHTPLTGPHTA------LTGSHTALTGSQTPLTGPHTALIGSQTPLTGPHTPLTSSHT 111

Query: 359 ----PYSSVTNPH----NPQSSITSSHFNINTNPHLSMGSPH------SNVNNSSHLTMD 496
               P++++T PH    +PQ+++TSSH  + T PH ++ SPH           SS   + 
Sbjct: 112 ALTGPHTALTGPHTPLTSPQTALTSSHTAL-TGPHTALMSPHIVLTGPHKALTSSQTPLT 170

Query: 497 SPRSNVDSSFATNITSPHS 553
           SP+S + SS  T +T PH+
Sbjct: 171 SPQSALTSSH-TALTGPHT 188



 Score = 56.6 bits (135), Expect = 1e-05
 Identities = 32/88 (36%), Positives = 52/88 (59%)
 Frame = +2

Query: 200 TGLHNPQSGVTNSHLNNLNMGSLHTAINNLHSGLSNPHSSVTNPHNPHSSTHNPYSSVTN 379
           T L +PQS +T+SH     +   HTA  + H+ L+ PH+++T P  P +S+H   +++T 
Sbjct: 167 TPLTSPQSALTSSHTA---LTGPHTAPTSPHTPLTGPHTALTGPQTPLTSSH---TALTG 220

Query: 380 PHNPQSSITSSHFNINTNPHLSMGSPHS 463
           PH P   +T  H  + T PH ++ SPH+
Sbjct: 221 PHTP---LTGPHTAL-TGPHTALTSPHA 244


>ref|XP_008469257.1| PREDICTED: uncharacterized protein DDB_G0283357-like [Diaphorina
           citri]
          Length = 446

 Score = 63.5 bits (153), Expect = 8e-08
 Identities = 45/160 (28%), Positives = 72/160 (45%), Gaps = 6/160 (3%)
 Frame = +2

Query: 80  NSPHSDVKLN--IGSSHLNVTNPYSNFGYXXXXXXXXXXXXXTGLHNPQSGVTNSHLNNL 253
           N P +  +L+  +G+++L    P     Y                H   S   NS LNN+
Sbjct: 127 NGPPAQQRLDSLVGNNNLPPEPPERVSSYAVMSSTLRSPVMSNEYHINTSHPINSTLNNI 186

Query: 254 NMGSLHTAINNLHSGLSNPHSSVTNPHNPHSSTHNPYSSVTNPHNPQSSITSSHFNINTN 433
           N    H  +N+ HS +++ H+++ + HN  +S+HN  +S  N  N   +  +S  N   +
Sbjct: 187 NAS--HITMNSSHSTMNSSHNTMNSSHNTMNSSHNTMNSSHNTMNSSHNTLNSSHNTTNS 244

Query: 434 PHLSMGSPHSNVNNSSHLTMDSPRS----NVDSSFATNIT 541
             L+M S H+   NS+H T  +  S    N  SS  TN T
Sbjct: 245 SQLTMNSSHNTTMNSTHNTTHNASSHDSNNNPSSATTNAT 284


>emb|CRH00261.1| conserved Plasmodium protein, unknown function [Plasmodium
           relictum]
          Length = 1729

 Score = 63.2 bits (152), Expect = 2e-07
 Identities = 42/154 (27%), Positives = 83/154 (53%), Gaps = 1/154 (0%)
 Frame = +2

Query: 107 NIGSSHLNVTNPYSNFGYXXXXXXXXXXXXXTGLHNPQSGVTNSHLNNLNMGSLHTAINN 286
           N+  +  N+TN  +N                T L+N  + + N   N   M S+HT +N 
Sbjct: 125 NMPGNMNNITNTMNNLPTNMKNIPTNMKNIPTNLNNMPTNMNNIPTN---MNSMHTNMNK 181

Query: 287 LHSGLSNPHSSVTNPHNPHSSTHNPYSSVTNPHNP-QSSITSSHFNINTNPHLSMGSPHS 463
           +H+ +SN H+++ N HN   + HN  ++++N  N   S++ + H N+N  P  SM +  +
Sbjct: 182 MHTNMSNIHTNMNNIHNNMGNIHNNMNNMSNSLNKLPSNMNNMHNNLNKIPS-SMSNIPN 240

Query: 464 NVNNSSHLTMDSPRSNVDSSFATNITSPHSHLNS 565
           N+NN S   M++  +N+ S+ ++N+++  +++N+
Sbjct: 241 NMNNMSS-NMNNMSNNM-SNMSSNMSNMPNNMNN 272


>ref|XP_009061035.1| hypothetical protein LOTGIDRAFT_165765 [Lottia gigantea]
 gb|ESO88322.1| hypothetical protein LOTGIDRAFT_165765 [Lottia gigantea]
          Length = 158

 Score = 59.3 bits (142), Expect = 3e-07
 Identities = 43/127 (33%), Positives = 65/127 (51%), Gaps = 7/127 (5%)
 Frame = +2

Query: 209 HNPQSGVTNSHLNNLNMGSLHTA---INNLHSGLSNPHSSVT-NPHNPHSSTHNPYSSVT 376
           H P S   NSH  N +  + HT     NN H+  S+ ++S T N H P+S T N ++   
Sbjct: 15  HIPNSHTLNSHTLNSHSNNRHTPNSHTNNRHTPNSHTNNSRTNNRHTPNSHTDNRHT--P 72

Query: 377 NPHNPQSSITSSHF-NINTNPHLSMGSPHSN--VNNSSHLTMDSPRSNVDSSFATNITSP 547
           N H P S   +SH  N +TN   +  S  +N   NNS      +P+S+ ++S+  N  +P
Sbjct: 73  NSHTPNSDTNNSHTPNSHTNNRHTPNSHTNNCQTNNSRTNNRHTPKSHTNNSYKPNSHTP 132

Query: 548 HSHLNSS 568
           +S  N+S
Sbjct: 133 YSDTNNS 139



 Score = 55.5 bits (132), Expect = 7e-06
 Identities = 46/138 (33%), Positives = 61/138 (44%), Gaps = 17/138 (12%)
 Frame = +2

Query: 209 HNPQSGVTNSHLNNLNMGSLHTAINNLHSGLSNPHSSVTNP-HNPHSST--------HNP 361
           H   S   NSH NN +  + HT  NN H+  S+ ++S TN  H P+S T        H P
Sbjct: 20  HTLNSHTLNSHSNNRHTPNSHT--NNRHTPNSHTNNSRTNNRHTPNSHTDNRHTPNSHTP 77

Query: 362 YSSVTNPHNPQSSITSSHF-NINTNPHLSMGS-------PHSNVNNSSHLTMDSPRSNVD 517
            S   N H P S   + H  N +TN   +  S       P S+ NNS       P S+  
Sbjct: 78  NSDTNNSHTPNSHTNNRHTPNSHTNNCQTNNSRTNNRHTPKSHTNNSY-----KPNSHTP 132

Query: 518 SSFATNITSPHSHLNSSY 571
            S   N  +P+SH N S+
Sbjct: 133 YSDTNNSNTPNSHTNYSH 150


>gb|OAG31008.1| hypothetical protein NEIG_00605 [Nematocida sp. ERTm5]
          Length = 307

 Score = 61.2 bits (147), Expect = 3e-07
 Identities = 39/122 (31%), Positives = 63/122 (51%), Gaps = 8/122 (6%)
 Frame = +2

Query: 209 HNPQSGVTNSHLNNLN----MGSLHTAINNLHSGLSNPHSSVTNPH----NPHSSTHNPY 364
           H+  S ++N+     N    + S H+ I+N HS   N HS+V+N H    N HS+ HN +
Sbjct: 29  HSTHSTISNAQCIKSNAHSTLNSTHSTISNAHSTRHNTHSTVSNTHSTISNAHSTRHNAH 88

Query: 365 SSVTNPHNPQSSITSSHFNINTNPHLSMGSPHSNVNNSSHLTMDSPRSNVDSSFATNITS 544
           S+++N H+  S+  +S  +   N   S  S  SN  NS+H T+ +  S   ++ +T   S
Sbjct: 89  STISNTHSTISNTLNSTLSNTLN---STHSTLSNTLNSAHSTISNAHSTRHNAHSTVSNS 145

Query: 545 PH 550
            H
Sbjct: 146 VH 147



 Score = 60.5 bits (145), Expect = 6e-07
 Identities = 31/107 (28%), Positives = 64/107 (59%), Gaps = 4/107 (3%)
 Frame = +2

Query: 263 SLHTAINNLHSGLSNPHSSVTNPH----NPHSSTHNPYSSVTNPHNPQSSITSSHFNINT 430
           S H+ I+N     SN HS++ + H    N HS+ HN +S+V+N H   S+I+++H +   
Sbjct: 30  STHSTISNAQCIKSNAHSTLNSTHSTISNAHSTRHNTHSTVSNTH---STISNAH-STRH 85

Query: 431 NPHLSMGSPHSNVNNSSHLTMDSPRSNVDSSFATNITSPHSHLNSSY 571
           N H ++ + HS ++N+ + T+ +  ++  S+ +  + S HS +++++
Sbjct: 86  NAHSTISNTHSTISNTLNSTLSNTLNSTHSTLSNTLNSAHSTISNAH 132


>ref|XP_014857843.1| PREDICTED: merozoite surface protein CMZ-8-like isoform X1
           [Poecilia mexicana]
          Length = 166

 Score = 56.2 bits (134), Expect = 4e-06
 Identities = 33/99 (33%), Positives = 49/99 (49%), Gaps = 7/99 (7%)
 Frame = +2

Query: 209 HNPQSGVTNSHLNNLNMGSLHTAINNLHSGLSNPHSSVTNPHNPHSSTHNPYSSVTNPHN 388
           H+P+S   +         S H   ++ H   S+PH   ++PHNP SS H+P SS  +P +
Sbjct: 49  HDPESSPHDPE------SSPHDPESSPHDPESSPHDPESSPHNPESSPHDPESSPHDPES 102

Query: 389 PQSSITSSHFNINTNPHLSMGSPH-------SNVNNSSH 484
           P     SS  N  ++PH    SPH       S++N +SH
Sbjct: 103 PPHDPESSLHNPESSPHDPESSPHDPESSLLSHINTNSH 141