BLASTX nr result
ID: Ophiopogon26_contig00012502
seq
BLASTX 2.2.26 [Sep-21-2011]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Ophiopogon26_contig00012502
(688 letters)
Database: All non-redundant GenBank CDS
translations+PDB+SwissProt+PIR+PRF excluding environmental samples
from WGS projects
149,584,005 sequences; 54,822,741,787 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
ref|XP_020257503.1| protein FRIGIDA-ESSENTIAL 1-like [Asparagus ... 122 3e-28
gb|ONK75672.1| uncharacterized protein A4U43_C03F19330 [Asparagu... 122 3e-28
ref|XP_019702322.1| PREDICTED: zinc finger CCCH domain-containin... 88 3e-16
ref|XP_010928945.1| PREDICTED: zinc finger CCCH domain-containin... 88 3e-16
ref|XP_017696184.1| PREDICTED: zinc finger CCCH domain-containin... 86 1e-15
ref|XP_008777661.1| PREDICTED: zinc finger CCCH domain-containin... 86 1e-15
ref|XP_010272379.1| PREDICTED: protein FRIGIDA-ESSENTIAL 1 isofo... 80 1e-13
ref|XP_010272377.1| PREDICTED: zinc finger CCCH domain-containin... 80 1e-13
gb|OVA00361.1| zinc finger protein [Macleaya cordata] 68 2e-09
gb|PKA62841.1| Zinc finger CCCH domain-containing protein 27 [Ap... 63 7e-08
ref|XP_020573813.1| zinc finger CCCH domain-containing protein 3... 62 2e-07
ref|XP_021635065.1| protein FRIGIDA-ESSENTIAL 1 isoform X4 [Heve... 62 3e-07
ref|XP_021635064.1| protein FRIGIDA-ESSENTIAL 1 isoform X3 [Heve... 62 3e-07
ref|XP_021635062.1| protein FRIGIDA-ESSENTIAL 1 isoform X2 [Heve... 62 3e-07
ref|XP_021635061.1| protein FRIGIDA-ESSENTIAL 1 isoform X1 [Heve... 62 3e-07
ref|XP_020677919.1| zinc finger CCCH domain-containing protein 3... 60 6e-07
>ref|XP_020257503.1| protein FRIGIDA-ESSENTIAL 1-like [Asparagus officinalis]
Length = 690
Score = 122 bits (306), Expect = 3e-28
Identities = 83/221 (37%), Positives = 103/221 (46%)
Frame = +3
Query: 24 SEIFLTRRYLHDEQLQQEMPKREFLNDSPFSRCHSLASSEVPEHRXXXXXXXXXXXXXXX 203
S FL RR L +EQ+QQE+PKREF N+SP SR +SL + VP+ R
Sbjct: 315 SRHFLPRRSLDEEQVQQEIPKREFRNESPLSRGYSLTAPAVPDDRNYLGDSSISSCLYPN 374
Query: 204 XXXPDARCRRTEDFAFRRHQSSFPLHXXXXXXXXXXXXXXXXXXXYQPNPASSFSTERFD 383
RR+EDFAFR + SF S+FS
Sbjct: 375 NDDQFGHERRSEDFAFRNLRGSFD---------------------------STFS----- 402
Query: 384 VYKSFGLDKGYHXXXXXXXXXXXXXXXXXXEAETGLLHNTQRDLPAFIRQKMEAQESSWE 563
YKS L + ++HN RDLP +RQ++E SSWE
Sbjct: 403 -YKSLSLPRSSSPYFSRPEV-------------NNVVHNLSRDLPDSVRQRLERLRSSWE 448
Query: 564 PSVPFRPSFHYALPSLFSPGNQYDPLLDSIEPRNTRNIALQ 686
PSVPFRPSF+ A L S G+QYDPL DSIEP ++RN LQ
Sbjct: 449 PSVPFRPSFNLAPAILSSAGSQYDPLTDSIEPHDSRNTFLQ 489
>gb|ONK75672.1| uncharacterized protein A4U43_C03F19330 [Asparagus officinalis]
Length = 725
Score = 122 bits (306), Expect = 3e-28
Identities = 83/221 (37%), Positives = 103/221 (46%)
Frame = +3
Query: 24 SEIFLTRRYLHDEQLQQEMPKREFLNDSPFSRCHSLASSEVPEHRXXXXXXXXXXXXXXX 203
S FL RR L +EQ+QQE+PKREF N+SP SR +SL + VP+ R
Sbjct: 350 SRHFLPRRSLDEEQVQQEIPKREFRNESPLSRGYSLTAPAVPDDRNYLGDSSISSCLYPN 409
Query: 204 XXXPDARCRRTEDFAFRRHQSSFPLHXXXXXXXXXXXXXXXXXXXYQPNPASSFSTERFD 383
RR+EDFAFR + SF S+FS
Sbjct: 410 NDDQFGHERRSEDFAFRNLRGSFD---------------------------STFS----- 437
Query: 384 VYKSFGLDKGYHXXXXXXXXXXXXXXXXXXEAETGLLHNTQRDLPAFIRQKMEAQESSWE 563
YKS L + ++HN RDLP +RQ++E SSWE
Sbjct: 438 -YKSLSLPRSSSPYFSRPEV-------------NNVVHNLSRDLPDSVRQRLERLRSSWE 483
Query: 564 PSVPFRPSFHYALPSLFSPGNQYDPLLDSIEPRNTRNIALQ 686
PSVPFRPSF+ A L S G+QYDPL DSIEP ++RN LQ
Sbjct: 484 PSVPFRPSFNLAPAILSSAGSQYDPLTDSIEPHDSRNTFLQ 524
>ref|XP_019702322.1| PREDICTED: zinc finger CCCH domain-containing protein 36 isoform X2
[Elaeis guineensis]
Length = 839
Score = 87.8 bits (216), Expect = 3e-16
Identities = 74/248 (29%), Positives = 101/248 (40%), Gaps = 20/248 (8%)
Frame = +3
Query: 3 MDEKRPASEIFLTRRYLHDEQLQQEMPKREFLNDSPFSRCHSLASSE-VPEHRXXXXXXX 179
MDE+ AS FL+RRYL + +L QEMPK EFLND+ FSR L+ + + E
Sbjct: 402 MDERHSASGEFLSRRYLDEGKLHQEMPKEEFLNDATFSRASPLSRNPLILESGYYSEQSS 461
Query: 180 XXXXXXXXXXXPDARCRRTEDFAFRRHQSSFPL-HXXXXXXXXXXXXXXXXXXXYQPNPA 356
+ + TED A QS FP +QP
Sbjct: 462 AAAGLYQNSNNSYSHGKMTEDVAIGYQQSRFPPPDPKYCSYSLSSSSNLRFDNSFQPLSG 521
Query: 357 SS------------------FSTERFDVYKSFGLDKGYHXXXXXXXXXXXXXXXXXXEAE 482
S S E FD ++F ++GY+ E
Sbjct: 522 SPPVQTLAQTGTSSTSRSMPLSAEHFDSNRTFNFNRGYYGSRSASLPSNSSPYYSRSEIG 581
Query: 483 TGLLHNTQRDLPAFIRQKMEAQESSWEPSVPFRPSFHYALPSLFSPGNQYDPLLDSIEPR 662
+ + + D+P K+ Q +SWEPS F+ SF A S SPG+QYDPL+DSIE
Sbjct: 582 SNMQQDILADVPPSAGSKI--QVNSWEPSERFQSSF-CAPASKPSPGSQYDPLIDSIEHP 638
Query: 663 NTRNIALQ 686
N+ +Q
Sbjct: 639 KAGNVTIQ 646
>ref|XP_010928945.1| PREDICTED: zinc finger CCCH domain-containing protein 36 isoform X1
[Elaeis guineensis]
Length = 903
Score = 87.8 bits (216), Expect = 3e-16
Identities = 74/248 (29%), Positives = 101/248 (40%), Gaps = 20/248 (8%)
Frame = +3
Query: 3 MDEKRPASEIFLTRRYLHDEQLQQEMPKREFLNDSPFSRCHSLASSE-VPEHRXXXXXXX 179
MDE+ AS FL+RRYL + +L QEMPK EFLND+ FSR L+ + + E
Sbjct: 466 MDERHSASGEFLSRRYLDEGKLHQEMPKEEFLNDATFSRASPLSRNPLILESGYYSEQSS 525
Query: 180 XXXXXXXXXXXPDARCRRTEDFAFRRHQSSFPL-HXXXXXXXXXXXXXXXXXXXYQPNPA 356
+ + TED A QS FP +QP
Sbjct: 526 AAAGLYQNSNNSYSHGKMTEDVAIGYQQSRFPPPDPKYCSYSLSSSSNLRFDNSFQPLSG 585
Query: 357 SS------------------FSTERFDVYKSFGLDKGYHXXXXXXXXXXXXXXXXXXEAE 482
S S E FD ++F ++GY+ E
Sbjct: 586 SPPVQTLAQTGTSSTSRSMPLSAEHFDSNRTFNFNRGYYGSRSASLPSNSSPYYSRSEIG 645
Query: 483 TGLLHNTQRDLPAFIRQKMEAQESSWEPSVPFRPSFHYALPSLFSPGNQYDPLLDSIEPR 662
+ + + D+P K+ Q +SWEPS F+ SF A S SPG+QYDPL+DSIE
Sbjct: 646 SNMQQDILADVPPSAGSKI--QVNSWEPSERFQSSF-CAPASKPSPGSQYDPLIDSIEHP 702
Query: 663 NTRNIALQ 686
N+ +Q
Sbjct: 703 KAGNVTIQ 710
>ref|XP_017696184.1| PREDICTED: zinc finger CCCH domain-containing protein 36-like isoform
X2 [Phoenix dactylifera]
Length = 890
Score = 85.9 bits (211), Expect = 1e-15
Identities = 71/248 (28%), Positives = 103/248 (41%), Gaps = 20/248 (8%)
Frame = +3
Query: 3 MDEKRPASEIFLTRRYLHDEQLQQEMPKREFLNDSPFSRCHSLASSE-VPEHRXXXXXXX 179
+DE+R A+ FL+RRYL + +L QEMPK EFLN++ FS L+ + +PE+
Sbjct: 452 LDERRLANGEFLSRRYLDEGKLHQEMPKGEFLNNATFSSISPLSRNPLIPEYGNYSARSS 511
Query: 180 XXXXXXXXXXXPDARCRRTEDFAFRRHQSSFPL-HXXXXXXXXXXXXXXXXXXXYQP--- 347
P + + ED A R QS FPL QP
Sbjct: 512 AATCLYQNSNNPYSYGKMVEDVAVRSQQSRFPLPDPKYTSYSLSSSLNSSFDSSLQPLHG 571
Query: 348 ---------------NPASSFSTERFDVYKSFGLDKGYHXXXXXXXXXXXXXXXXXXEAE 482
++ S E + ++SF D+GY+
Sbjct: 572 SPSFHLLPQIGASSTRGSAPLSAEHLESHRSFNFDRGYYGSRSASLPRKSSPYY-----S 626
Query: 483 TGLLHNTQRDLPAFIRQKMEAQESSWEPSVPFRPSFHYALPSLFSPGNQYDPLLDSIEPR 662
+ + D+P ++ +E+SWEPS FR S+ A PS SPG+QYDPL+D IE
Sbjct: 627 SSMQQGVVGDIPP--PAGLKIKENSWEPSECFRSSY-CAPPSKSSPGSQYDPLVDCIEHH 683
Query: 663 NTRNIALQ 686
N+ Q
Sbjct: 684 KAGNVTSQ 691
>ref|XP_008777661.1| PREDICTED: zinc finger CCCH domain-containing protein 36-like isoform
X1 [Phoenix dactylifera]
Length = 900
Score = 85.9 bits (211), Expect = 1e-15
Identities = 71/248 (28%), Positives = 103/248 (41%), Gaps = 20/248 (8%)
Frame = +3
Query: 3 MDEKRPASEIFLTRRYLHDEQLQQEMPKREFLNDSPFSRCHSLASSE-VPEHRXXXXXXX 179
+DE+R A+ FL+RRYL + +L QEMPK EFLN++ FS L+ + +PE+
Sbjct: 462 LDERRLANGEFLSRRYLDEGKLHQEMPKGEFLNNATFSSISPLSRNPLIPEYGNYSARSS 521
Query: 180 XXXXXXXXXXXPDARCRRTEDFAFRRHQSSFPL-HXXXXXXXXXXXXXXXXXXXYQP--- 347
P + + ED A R QS FPL QP
Sbjct: 522 AATCLYQNSNNPYSYGKMVEDVAVRSQQSRFPLPDPKYTSYSLSSSLNSSFDSSLQPLHG 581
Query: 348 ---------------NPASSFSTERFDVYKSFGLDKGYHXXXXXXXXXXXXXXXXXXEAE 482
++ S E + ++SF D+GY+
Sbjct: 582 SPSFHLLPQIGASSTRGSAPLSAEHLESHRSFNFDRGYYGSRSASLPRKSSPYY-----S 636
Query: 483 TGLLHNTQRDLPAFIRQKMEAQESSWEPSVPFRPSFHYALPSLFSPGNQYDPLLDSIEPR 662
+ + D+P ++ +E+SWEPS FR S+ A PS SPG+QYDPL+D IE
Sbjct: 637 SSMQQGVVGDIPP--PAGLKIKENSWEPSECFRSSY-CAPPSKSSPGSQYDPLVDCIEHH 693
Query: 663 NTRNIALQ 686
N+ Q
Sbjct: 694 KAGNVTSQ 701
>ref|XP_010272379.1| PREDICTED: protein FRIGIDA-ESSENTIAL 1 isoform X2 [Nelumbo
nucifera]
Length = 873
Score = 80.1 bits (196), Expect = 1e-13
Identities = 44/111 (39%), Positives = 56/111 (50%)
Frame = +3
Query: 354 ASSFSTERFDVYKSFGLDKGYHXXXXXXXXXXXXXXXXXXEAETGLLHNTQRDLPAFIRQ 533
+S+F + K DKGYH LLH+ RD P
Sbjct: 542 SSTFGIDPLAGQKHLDSDKGYHPSRSASLPRSSSSPFNSKLEAENLLHSVPRD-PPISGY 600
Query: 534 KMEAQESSWEPSVPFRPSFHYALPSLFSPGNQYDPLLDSIEPRNTRNIALQ 686
K + + WEPSVPFRPSFH++ S+ SPG+QYDPLLDSIEP + N + Q
Sbjct: 601 KSQFSSNDWEPSVPFRPSFHFSQTSISSPGSQYDPLLDSIEPPSGANRSFQ 651
>ref|XP_010272377.1| PREDICTED: zinc finger CCCH domain-containing protein 36 isoform X1
[Nelumbo nucifera]
Length = 874
Score = 80.1 bits (196), Expect = 1e-13
Identities = 44/111 (39%), Positives = 56/111 (50%)
Frame = +3
Query: 354 ASSFSTERFDVYKSFGLDKGYHXXXXXXXXXXXXXXXXXXEAETGLLHNTQRDLPAFIRQ 533
+S+F + K DKGYH LLH+ RD P
Sbjct: 543 SSTFGIDPLAGQKHLDSDKGYHPSRSASLPRSSSSPFNSKLEAENLLHSVPRD-PPISGY 601
Query: 534 KMEAQESSWEPSVPFRPSFHYALPSLFSPGNQYDPLLDSIEPRNTRNIALQ 686
K + + WEPSVPFRPSFH++ S+ SPG+QYDPLLDSIEP + N + Q
Sbjct: 602 KSQFSSNDWEPSVPFRPSFHFSQTSISSPGSQYDPLLDSIEPPSGANRSFQ 652
>gb|OVA00361.1| zinc finger protein [Macleaya cordata]
Length = 844
Score = 67.8 bits (164), Expect = 2e-09
Identities = 41/114 (35%), Positives = 55/114 (48%), Gaps = 1/114 (0%)
Frame = +3
Query: 348 NPASSFSTERFDVYKSFGLDKGYHXXXXXXXXXXXXXXXXXXEAETGL-LHNTQRDLPAF 524
+P+ S R+ K +G D+GY+ L LH D
Sbjct: 546 SPSQGSSPSRYQ--KPYGSDRGYYASRSTSLPRSSSSPFYSRPEPDNLPLHGVPMDPVIS 603
Query: 525 IRQKMEAQESSWEPSVPFRPSFHYALPSLFSPGNQYDPLLDSIEPRNTRNIALQ 686
+ K++A +WEPSVPFRPSFH + SP +QYDPLLDSIE N + +LQ
Sbjct: 604 VGHKLQATSYNWEPSVPFRPSFHLPPNFISSPSSQYDPLLDSIELPNIGDRSLQ 657
>gb|PKA62841.1| Zinc finger CCCH domain-containing protein 27 [Apostasia
shenzhenica]
Length = 658
Score = 63.2 bits (152), Expect = 7e-08
Identities = 38/108 (35%), Positives = 52/108 (48%)
Frame = +3
Query: 348 NPASSFSTERFDVYKSFGLDKGYHXXXXXXXXXXXXXXXXXXEAETGLLHNTQRDLPAFI 527
N S+ S + + + SF D+G H GL H+ D P
Sbjct: 374 NRGSTPSADCIEGHNSFDFDRGCHRSRSASLTRNFSPYR-------GLAHHNVLDDP-LS 425
Query: 528 RQKMEAQESSWEPSVPFRPSFHYALPSLFSPGNQYDPLLDSIEPRNTR 671
QK + + +WEPS PFRPSF ++ SP +QYDP+LDSIEP + R
Sbjct: 426 WQKTKTEYDAWEPSQPFRPSFSLVTSNISSPQSQYDPILDSIEPESAR 473
>ref|XP_020573813.1| zinc finger CCCH domain-containing protein 36-like [Phalaenopsis
equestris]
Length = 723
Score = 62.0 bits (149), Expect = 2e-07
Identities = 65/234 (27%), Positives = 90/234 (38%), Gaps = 18/234 (7%)
Frame = +3
Query: 12 KRPASEIFLTRRYLHDEQLQQEMPKREFLNDSPFSRCHS----LASSEVPEHRXXXXXXX 179
+R + + FL+RR+L + + E+ +NDSP+ R S A + V + +
Sbjct: 310 ERQSDDAFLSRRHLTEGKALNEIS----MNDSPYERTISGRTHPADAFVSDPKHYPGSSS 365
Query: 180 XXXXXXXXXXXPDARCRRTEDFAFRRHQSSFPLHXXXXXXXXXXXXXXXXXXXYQ----- 344
P A RTE A R QS F +Q
Sbjct: 366 ISSILQHNNNSPPAY-GRTEGNAIRSTQSHFLKQESYDSHGFAGSLSSGLGSSFQLPQMD 424
Query: 345 -------PNPASSFS--TERFDVYKSFGLDKGYHXXXXXXXXXXXXXXXXXXEAETGLLH 497
P+PAS + TE + + L + YH E + H
Sbjct: 425 YMLSRAGPSPASGSTRNTEYVEGHSFLDLHRRYHSSGSISLTRDSSPYLSQPELRNKIHH 484
Query: 498 NTQRDLPAFIRQKMEAQESSWEPSVPFRPSFHYALPSLFSPGNQYDPLLDSIEP 659
N DL +RQ + Q +WEPS PFR S A S SP +QYDP+LDSIEP
Sbjct: 485 NISGDLT--LRQTTKIQYDAWEPSQPFRSSLAIATKSTSSP-SQYDPILDSIEP 535
>ref|XP_021635065.1| protein FRIGIDA-ESSENTIAL 1 isoform X4 [Hevea brasiliensis]
Length = 807
Score = 61.6 bits (148), Expect = 3e-07
Identities = 37/105 (35%), Positives = 47/105 (44%)
Frame = +3
Query: 354 ASSFSTERFDVYKSFGLDKGYHXXXXXXXXXXXXXXXXXXEAETGLLHNTQRDLPAFIRQ 533
+SS +T F K D+ YH E ET LL + R +
Sbjct: 481 SSSLNTSPFGSQKLSDNDRNYHASRSLRQSASLLFGS---ERETSLLTSVSRGPLHYAEH 537
Query: 534 KMEAQESSWEPSVPFRPSFHYALPSLFSPGNQYDPLLDSIEPRNT 668
K + + WEPS+PFRPSF SPG+QYDPL DSI+ T
Sbjct: 538 KAKISSNDWEPSIPFRPSFSITYTVASSPGSQYDPLRDSIDLSTT 582
>ref|XP_021635064.1| protein FRIGIDA-ESSENTIAL 1 isoform X3 [Hevea brasiliensis]
Length = 856
Score = 61.6 bits (148), Expect = 3e-07
Identities = 37/105 (35%), Positives = 47/105 (44%)
Frame = +3
Query: 354 ASSFSTERFDVYKSFGLDKGYHXXXXXXXXXXXXXXXXXXEAETGLLHNTQRDLPAFIRQ 533
+SS +T F K D+ YH E ET LL + R +
Sbjct: 530 SSSLNTSPFGSQKLSDNDRNYHASRSLRQSASLLFGS---ERETSLLTSVSRGPLHYAEH 586
Query: 534 KMEAQESSWEPSVPFRPSFHYALPSLFSPGNQYDPLLDSIEPRNT 668
K + + WEPS+PFRPSF SPG+QYDPL DSI+ T
Sbjct: 587 KAKISSNDWEPSIPFRPSFSITYTVASSPGSQYDPLRDSIDLSTT 631
>ref|XP_021635062.1| protein FRIGIDA-ESSENTIAL 1 isoform X2 [Hevea brasiliensis]
Length = 857
Score = 61.6 bits (148), Expect = 3e-07
Identities = 37/105 (35%), Positives = 47/105 (44%)
Frame = +3
Query: 354 ASSFSTERFDVYKSFGLDKGYHXXXXXXXXXXXXXXXXXXEAETGLLHNTQRDLPAFIRQ 533
+SS +T F K D+ YH E ET LL + R +
Sbjct: 531 SSSLNTSPFGSQKLSDNDRNYHASRSLRQSASLLFGS---ERETSLLTSVSRGPLHYAEH 587
Query: 534 KMEAQESSWEPSVPFRPSFHYALPSLFSPGNQYDPLLDSIEPRNT 668
K + + WEPS+PFRPSF SPG+QYDPL DSI+ T
Sbjct: 588 KAKISSNDWEPSIPFRPSFSITYTVASSPGSQYDPLRDSIDLSTT 632
>ref|XP_021635061.1| protein FRIGIDA-ESSENTIAL 1 isoform X1 [Hevea brasiliensis]
Length = 859
Score = 61.6 bits (148), Expect = 3e-07
Identities = 37/105 (35%), Positives = 47/105 (44%)
Frame = +3
Query: 354 ASSFSTERFDVYKSFGLDKGYHXXXXXXXXXXXXXXXXXXEAETGLLHNTQRDLPAFIRQ 533
+SS +T F K D+ YH E ET LL + R +
Sbjct: 533 SSSLNTSPFGSQKLSDNDRNYHASRSLRQSASLLFGS---ERETSLLTSVSRGPLHYAEH 589
Query: 534 KMEAQESSWEPSVPFRPSFHYALPSLFSPGNQYDPLLDSIEPRNT 668
K + + WEPS+PFRPSF SPG+QYDPL DSI+ T
Sbjct: 590 KAKISSNDWEPSIPFRPSFSITYTVASSPGSQYDPLRDSIDLSTT 634
>ref|XP_020677919.1| zinc finger CCCH domain-containing protein 36 [Dendrobium
catenatum]
gb|PKU74141.1| Zinc finger CCCH domain-containing protein 36 [Dendrobium
catenatum]
Length = 899
Score = 60.5 bits (145), Expect = 6e-07
Identities = 38/105 (36%), Positives = 50/105 (47%)
Frame = +3
Query: 345 PNPASSFSTERFDVYKSFGLDKGYHXXXXXXXXXXXXXXXXXXEAETGLLHNTQRDLPAF 524
PN S+ +TE + + LD+ Y E + HN DL +
Sbjct: 607 PNSGSTRNTEYLEGHSLLDLDRRYRGSGSISLTRDSSPYNSRSELRNMIHHNIPSDLTS- 665
Query: 525 IRQKMEAQESSWEPSVPFRPSFHYALPSLFSPGNQYDPLLDSIEP 659
RQ + Q +WEPS PFR S A S+ SP +QYDP+LDSIEP
Sbjct: 666 -RQTKKIQYDAWEPSQPFRSSLAIASKSISSP-SQYDPILDSIEP 708