BLASTX 2.2.26 [Sep-21-2011]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= Ophiopogon25_contig00043770
         (1337 letters)

Database: All non-redundant GenBank CDS
translations+PDB+SwissProt+PIR+PRF excluding environmental samples
from WGS projects 
           149,584,005 sequences; 54,822,741,787 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gb|EXX59686.1| dioxygenase BNA2 [Rhizophagus irregularis DAOM 19...   795   0.0  
gb|PKY50816.1| Indoleamine 2,3-dioxygenase [Rhizophagus irregula...   794   0.0  
dbj|GBC46549.1| Indoleamine 2,3-dioxygenase [Rhizophagus irregul...   365   e-121
gb|OAD04176.1| hypothetical protein MUCCIDRAFT_140241 [Mucor cir...   353   e-114
gb|ORZ10546.1| Indoleamine 2,3-dioxygenase [Absidia repens]           348   e-111
emb|CDS14488.1| hypothetical protein LRAMOSA06657 [Lichtheimia r...   345   e-110
emb|CDH56721.1| indoleamine-dioxygenase subfamily [Lichtheimia c...   345   e-109
gb|EPB89940.1| hypothetical protein HMPREF1544_03188 [Mucor circ...   344   e-109
dbj|GAN01973.1| indoleamine 2,3-dioxygenase subfamily [Mucor amb...   344   e-109
gb|OAQ23912.1| Indoleamine 2,3-dioxygenase [Mortierella elongata...   340   e-109
emb|CEG75499.1| hypothetical protein RMATCC62417_10531 [Rhizopus...   336   e-107
emb|CEP11056.1| hypothetical protein [Parasitella parasitica]         337   e-107
gb|ORE18396.1| Indoleamine 2,3-dioxygenase [Rhizopus microsporus]     336   e-106
ref|XP_023463810.1| Indoleamine 2,3-dioxygenase [Rhizopus micros...   335   e-106
gb|ORE11191.1| Indoleamine 2,3-dioxygenase [Rhizopus microsporus...   335   e-106
gb|EIE92414.1| hypothetical protein RO3G_16936 [Rhizopus delemar...   335   e-106
ref|XP_021883366.1| Indoleamine 2,3-dioxygenase [Lobosporangium ...   335   e-106
gb|KXN71802.1| Indoleamine 2,3-dioxygenase [Conidiobolus coronat...   332   e-105
ref|XP_019023834.1| Indoleamine 2,3-dioxygenase, partial [Saitoe...   327   e-105
gb|PIA19309.1| Indoleamine 2,3-dioxygenase [Coemansia reversa NR...   328   e-103

>gb|EXX59686.1| dioxygenase BNA2 [Rhizophagus irregularis DAOM 197198w]
 gb|PKC07104.1| Indoleamine 2,3-dioxygenase [Rhizophagus irregularis]
 gb|PKC63715.1| Indoleamine 2,3-dioxygenase [Rhizophagus irregularis]
 gb|PKK72340.1| Indoleamine 2,3-dioxygenase [Rhizophagus irregularis]
 gb|PKY16408.1| Indoleamine 2,3-dioxygenase [Rhizophagus irregularis]
 gb|POG77899.1| Indoleamine 2,3-dioxygenase [Rhizophagus irregularis DAOM 181602=DAOM
            197198]
          Length = 515

 Score =  795 bits (2054), Expect = 0.0
 Identities = 386/420 (91%), Positives = 388/420 (92%)
 Frame = +1

Query: 76   MAPNHSAPLISENTFNVPRLEDYDISPSTGFLPSIPPLQCLPDSYYEPWETLISMFHNLM 255
            MAPNHSAPLISENTFNVPRLEDYDISPSTGFLPSIPPL+CLPDSYYEPWETLISMFHNLM
Sbjct: 1    MAPNHSAPLISENTFNVPRLEDYDISPSTGFLPSIPPLECLPDSYYEPWETLISMFHNLM 60

Query: 256  LAGRLREYVKRLPILKTDRLKTPEEYRRAFLVLSFIAHGYVWGKYETVSDRLPANIAIPW 435
            LAGRLREYVKRLPILKTDRLKTPEEYRRAFLVLSFIAHGYVWGKYETVSDRLPANIAIPW
Sbjct: 61   LAGRLREYVKRLPILKTDRLKTPEEYRRAFLVLSFIAHGYVWGKYETVSDRLPANIAIPW 120

Query: 436  VEVSKYLDVAPIINHAAVVTWNWSLLFSDEPFKLNNLATLITFSNTLDESWFYLVTTAIE 615
            VEVSKYLDVAPIINHAAVVTWNWSLLFSDEPFKLNNLATLITFSNTLDESWFYLVTTAIE
Sbjct: 121  VEVSKYLDVAPIINHAAVVTWNWSLLFSDEPFKLNNLATLITFSNTLDESWFYLVTTAIE 180

Query: 616  GFGGRALTSIMAAIQATYDGXXXXXXXXXXXXSSTIFDINKTLQKMFKKCDPYVFYWKVR 795
            GFGGRALTSIMAAIQATYDG            SSTIFDINKTLQKMFKKCDPYVFYWKVR
Sbjct: 181  GFGGRALTSIMAAIQATYDGNNEILINELRNISSTIFDINKTLQKMFKKCDPYVFYWKVR 240

Query: 796  PYLSGWENEDRLPKGLIYDGVDGNDENGNPIYRRYIGGSAGQSALIQALDIALSVKHYPT 975
            PYLSGWENEDRLPKGLIY+GVDGNDENGNPIYRRYIGGSAGQSALIQALDIALSVKHYPT
Sbjct: 241  PYLSGWENEDRLPKGLIYEGVDGNDENGNPIYRRYIGGSAGQSALIQALDIALSVKHYPT 300

Query: 976  GIKPHTNSSCPRYTSCSNGYPQPHDIHQYVSNGHTEPQQPYLHRIRQNIPGPHRRFLEDL 1155
            GIKPHTNSSCPRYTSCSNGYPQPHDIHQYVSNGHTEPQQPYLHRIRQNIPGPHRRFLEDL
Sbjct: 301  GIKPHTNSSCPRYTSCSNGYPQPHDIHQYVSNGHTEPQQPYLHRIRQNIPGPHRRFLEDL 360

Query: 1156 AKIADIRNYIIXXXXXXXXXXXXXXXXXXXXCLLRETDEADDLIKAYNECLNQMKDFRKT 1335
            AKIADIRNYII                    CLLRETDEADDLIKAYNECLNQMKDFRKT
Sbjct: 361  AKIADIRNYIISTTNYDSSVNTSSSDESEDTCLLRETDEADDLIKAYNECLNQMKDFRKT 420


>gb|PKY50816.1| Indoleamine 2,3-dioxygenase [Rhizophagus irregularis]
          Length = 515

 Score =  794 bits (2050), Expect = 0.0
 Identities = 385/420 (91%), Positives = 387/420 (92%)
 Frame = +1

Query: 76   MAPNHSAPLISENTFNVPRLEDYDISPSTGFLPSIPPLQCLPDSYYEPWETLISMFHNLM 255
            MAPNHSAPL SENTFNVPRLEDYDISPSTGFLPSIPPL+CLPDSYYEPWETLISMFHNLM
Sbjct: 1    MAPNHSAPLFSENTFNVPRLEDYDISPSTGFLPSIPPLECLPDSYYEPWETLISMFHNLM 60

Query: 256  LAGRLREYVKRLPILKTDRLKTPEEYRRAFLVLSFIAHGYVWGKYETVSDRLPANIAIPW 435
            LAGRLREYVKRLPILKTDRLKTPEEYRRAFLVLSFIAHGYVWGKYETVSDRLPANIAIPW
Sbjct: 61   LAGRLREYVKRLPILKTDRLKTPEEYRRAFLVLSFIAHGYVWGKYETVSDRLPANIAIPW 120

Query: 436  VEVSKYLDVAPIINHAAVVTWNWSLLFSDEPFKLNNLATLITFSNTLDESWFYLVTTAIE 615
            VEVSKYLDVAPIINHAAVVTWNWSLLFSDEPFKLNNLATLITFSNTLDESWFYLVTTAIE
Sbjct: 121  VEVSKYLDVAPIINHAAVVTWNWSLLFSDEPFKLNNLATLITFSNTLDESWFYLVTTAIE 180

Query: 616  GFGGRALTSIMAAIQATYDGXXXXXXXXXXXXSSTIFDINKTLQKMFKKCDPYVFYWKVR 795
            GFGGRALTSIMAAIQATYDG            SSTIFDINKTLQKMFKKCDPYVFYWKVR
Sbjct: 181  GFGGRALTSIMAAIQATYDGNNEILINELRNISSTIFDINKTLQKMFKKCDPYVFYWKVR 240

Query: 796  PYLSGWENEDRLPKGLIYDGVDGNDENGNPIYRRYIGGSAGQSALIQALDIALSVKHYPT 975
            PYLSGWENEDRLPKGLIY+GVDGNDENGNPIYRRYIGGSAGQSALIQALDIALSVKHYPT
Sbjct: 241  PYLSGWENEDRLPKGLIYEGVDGNDENGNPIYRRYIGGSAGQSALIQALDIALSVKHYPT 300

Query: 976  GIKPHTNSSCPRYTSCSNGYPQPHDIHQYVSNGHTEPQQPYLHRIRQNIPGPHRRFLEDL 1155
            GIKPHTNSSCPRYTSCSNGYPQPHDIHQYVSNGHTEPQQPYLHRIRQNIPGPHRRFLEDL
Sbjct: 301  GIKPHTNSSCPRYTSCSNGYPQPHDIHQYVSNGHTEPQQPYLHRIRQNIPGPHRRFLEDL 360

Query: 1156 AKIADIRNYIIXXXXXXXXXXXXXXXXXXXXCLLRETDEADDLIKAYNECLNQMKDFRKT 1335
            AKIADIRNYII                    CLLRETDEADDLIKAYNECLNQMKDFRKT
Sbjct: 361  AKIADIRNYIISTTNYDSSVNTSSSDESEDTCLLRETDEADDLIKAYNECLNQMKDFRKT 420


>dbj|GBC46549.1| Indoleamine 2,3-dioxygenase [Rhizophagus irregularis DAOM 181602]
          Length = 366

 Score =  365 bits (938), Expect = e-121
 Identities = 184/240 (76%), Positives = 186/240 (77%)
 Frame = +1

Query: 76  MAPNHSAPLISENTFNVPRLEDYDISPSTGFLPSIPPLQCLPDSYYEPWETLISMFHNLM 255
           MAPNHSAPLISENTFNVPRLEDYDISPSTGFLPSIPPL+CLPDSYYEPWETLISMFHNLM
Sbjct: 1   MAPNHSAPLISENTFNVPRLEDYDISPSTGFLPSIPPLECLPDSYYEPWETLISMFHNLM 60

Query: 256 LAGRLREYVKRLPILKTDRLKTPEEYRRAFLVLSFIAHGYVWGKYETVSDRLPANIAIPW 435
           LAGRLREYVKRLPILKTDRLKTPEEYRRAFLVLSFIAHGYVWGKYETVSDRLPANIAIPW
Sbjct: 61  LAGRLREYVKRLPILKTDRLKTPEEYRRAFLVLSFIAHGYVWGKYETVSDRLPANIAIPW 120

Query: 436 VEVSKYLDVAPIINHAAVVTWNWSLLFSDEPFKLNNLATLITFSNTLDESWFYLVTTAIE 615
           VEVSKYLDVAPIINHAAVVTWNWSLLFSDEPFKLNNLATLITFSNTLDESW         
Sbjct: 121 VEVSKYLDVAPIINHAAVVTWNWSLLFSDEPFKLNNLATLITFSNTLDESWL-------- 172

Query: 616 GFGGRALTSIMAAIQATYDGXXXXXXXXXXXXSSTIFDINKTLQKMFKKCDPYVFYWKVR 795
                                                     L  MFKKCDPYVFYWK +
Sbjct: 173 ------------------------------------------LMMMFKKCDPYVFYWKCK 190



 Score =  112 bits (281), Expect = 6e-24
 Identities = 57/78 (73%), Positives = 58/78 (74%)
 Frame = +1

Query: 1102 HRIRQNIPGPHRRFLEDLAKIADIRNYIIXXXXXXXXXXXXXXXXXXXXCLLRETDEADD 1281
            +RIRQNIPGPHRRFLEDLAKIADIRNYII                    CLLRETDEADD
Sbjct: 194  NRIRQNIPGPHRRFLEDLAKIADIRNYIISTTNYDSSVNTSSSDESEDTCLLRETDEADD 253

Query: 1282 LIKAYNECLNQMKDFRKT 1335
            LIKAYNECLNQMKDFRKT
Sbjct: 254  LIKAYNECLNQMKDFRKT 271


>gb|OAD04176.1| hypothetical protein MUCCIDRAFT_140241 [Mucor circinelloides f.
            lusitanicus CBS 277.49]
          Length = 499

 Score =  353 bits (905), Expect = e-114
 Identities = 188/415 (45%), Positives = 252/415 (60%), Gaps = 16/415 (3%)
 Frame = +1

Query: 133  LEDYDISPSTGFLPSIPPLQCLPDSYYEPWETLISMFHNLMLAGRLREYVKRLPILKTDR 312
            LEDYDIS  TGFLPS PPL+ L D Y+ PWE ++  F+ L+LAG+LRE V ++P+L   +
Sbjct: 4    LEDYDISVKTGFLPSTPPLRRLSDPYFAPWEEMMDDFNGLLLAGKLREKVHKMPLLDHTQ 63

Query: 313  LKTPEEYRRAFLVLSFIAHGYVWGKYETVSDRLPANIAIPWVEVSKYLDVAPIINHAAVV 492
            LK+ EEYRRAFL+L  ++H YVWGK+ET S+ LP+N+AIPW  ++ +L + P++ HAAVV
Sbjct: 64   LKSVEEYRRAFLILCMVSHSYVWGKHETTSETLPSNLAIPWTSIADHLGLCPVVCHAAVV 123

Query: 493  TWNWSLLFSDEPFKLNNLATLITFSNTLDESWFYLVTTAIEGFGGRALTSIMAAIQATYD 672
             WN+ LL  + P  L+NLA L T+S +LDESWFYL+TTAIE  G   L+ I  AI   + 
Sbjct: 124  LWNYRLLDKEGPIDLSNLAALATYSGSLDESWFYLITTAIESSGAPCLSQITYAIDNIHQ 183

Query: 673  GXXXXXXXXXXXXSSTIFDINKTLQKMFKKCDPYVFYWKVRPYLSGWEN--EDRLPKGLI 846
            G             + + ++N  L++M++KCDPYVFYWK+RPYL+GWEN  E  LP GLI
Sbjct: 184  GKYGDLKQNLETIRTALANMNDDLKRMYEKCDPYVFYWKIRPYLAGWENMAEAGLPLGLI 243

Query: 847  YDGVDGNDENGNPIYRRYIGGSAGQSALIQALDIALSVKHYPTGIKPHTNSSC----PRY 1014
            Y+GVD         YRRY GGSA QS+LI ALD+A  V+H+ TG KP    +      RY
Sbjct: 244  YEGVDALQ------YRRYAGGSAAQSSLIAALDVAFGVEHHRTGEKPSFIKAADLPNDRY 297

Query: 1015 TSCSNGYPQPHDIHQYVSNGHTEPQQP----------YLHRIRQNIPGPHRRFLEDLAKI 1164
            T      P        ++NG   P+ P          +L  +R+ +P PHR FLEDL + 
Sbjct: 298  TKLPATNPADE-----INNGAETPRTPPRFKRTNRNTFLRAMRKYMPRPHREFLEDLEEA 352

Query: 1165 ADIRNYIIXXXXXXXXXXXXXXXXXXXXCLLRETDEADDLIKAYNECLNQMKDFR 1329
            A+IR YI+                         T E  +++KAYNECL+Q+K FR
Sbjct: 353  ANIRPYILQLEENDKNGNI--------------TAEELEIVKAYNECLHQLKLFR 393


>gb|ORZ10546.1| Indoleamine 2,3-dioxygenase [Absidia repens]
          Length = 607

 Score =  348 bits (894), Expect = e-111
 Identities = 191/447 (42%), Positives = 257/447 (57%), Gaps = 48/447 (10%)
 Frame = +1

Query: 133  LEDYDISPSTGFLPSIPPLQCLPDSYYEPWETLISMFHNLMLAGRLREYVKRLPILKTDR 312
            LE+YDISP TGFLP  PPL+ L D Y+ PWE ++  F+ L+LAG+LR  + ++P+L   +
Sbjct: 4    LEEYDISPVTGFLPHDPPLRRLSDPYFTPWEDMMDDFNGLLLAGKLRAKIHKMPMLNHKK 63

Query: 313  LKTPEEYRRAFLVLSFIAHGYVWGKYETVSDRLPANIAIPWVEVSKYLDVAPIINHAAVV 492
            L T +EYRRAFL+L  ++H YVWGK+E  S+ LPAN+A+PW  +++YL + P++ HAAVV
Sbjct: 64   LNTVQEYRRAFLILCMLSHSYVWGKHEEASETLPANLAVPWNAIAEYLGLCPVVCHAAVV 123

Query: 493  TWNWSLLFSDEPFKLNNLATLITFSNTLDESWFYLVTTAIEGFGGRALTSIMAAIQATYD 672
             WN+ LL S+ P  L NL TL T+S +LDESWFYLVTTAIE  G +   SI++ +    D
Sbjct: 124  LWNYRLLDSEGPIDLGNLTTLATYSGSLDESWFYLVTTAIESAGSKCPASILSCVNNIQD 183

Query: 673  GXXXXXXXXXXXXSSTIFDINKTLQKMFKKCDPYVFYWKVRPYLSGWEN--EDRLPKGLI 846
            G              ++ DIN  L +MF+KCDPYVFYWK+RPYL+GWEN  E  LP GLI
Sbjct: 184  GNYEGLQANLTTIRDSLADINDVLHRMFEKCDPYVFYWKIRPYLAGWENMAEAGLPLGLI 243

Query: 847  YDGVDGN------DE--------NGNPI---YRRYIGGSAGQSALIQALDIALSVKHYPT 975
            Y+GV+ +      DE         G  +   YRRY GGSA QS+LI A D+A  V+H+P 
Sbjct: 244  YEGVNDSIWSAETDEYADISHLTEGERLLRQYRRYAGGSAAQSSLIAAFDVAFGVEHHPV 303

Query: 976  GIKPHTNSSCP---------------------RYTSCSNGYPQPHDIHQYVSNGHTEPQQ 1092
            G KP T+SS P                     RY    +  P     H   S+G T P+ 
Sbjct: 304  GEKPTTSSSSPLVIKLDTATTTSPSSPVDKHDRYRHLPSTRPADELDHSGTSSGATTPRP 363

Query: 1093 PY--------LHRIRQNIPGPHRRFLEDLAKIADIRNYIIXXXXXXXXXXXXXXXXXXXX 1248
            PY        L  +R+ +P  HR +LEDL   A+IR +++                    
Sbjct: 364  PYKRTNRNAFLRAMRKYMPEKHRDYLEDLETAANIRPFMMHLESLLHTGEI--------- 414

Query: 1249 CLLRETDEADDLIKAYNECLNQMKDFR 1329
                 +DE  DLI+ YN+CL+Q+K FR
Sbjct: 415  -----SDEERDLIRLYNDCLHQLKLFR 436


>emb|CDS14488.1| hypothetical protein LRAMOSA06657 [Lichtheimia ramosa]
          Length = 590

 Score =  345 bits (886), Expect = e-110
 Identities = 190/438 (43%), Positives = 254/438 (57%), Gaps = 39/438 (8%)
 Frame = +1

Query: 133  LEDYDISPSTGFLPSIPPLQCLPDSYYEPWETLISMFHNLMLAGRLREYVKRLPILKTDR 312
            LE+YDISP TGFLP  PPL+ LPD Y+ PWE+++  F+ L+LAG+LR  V+++P+L   R
Sbjct: 10   LEEYDISPKTGFLPPEPPLRRLPDPYFAPWESMMDDFNGLLLAGKLRRSVEKMPMLDHRR 69

Query: 313  LKTPEEYRRAFLVLSFIAHGYVWGKYETVSDRLPANIAIPWVEVSKYLDVAPIINHAAVV 492
            LKT  EYRRAFLVL  I+HGYVWGK+E  S+ LPAN+A+PW  ++ +L + P++ +AAVV
Sbjct: 70   LKTTPEYRRAFLVLCMISHGYVWGKHEKTSETLPANLAVPWTGIANHLGLCPVVCNAAVV 129

Query: 493  TWNWSLLFSDEPFKLNNLATLITFSNTLDESWFYLVTTAIEGFGGRALTSIMAAIQATYD 672
             WN+ LL  + P  L+NLA L T+S +LDE+WFYLVTTAIE  G  ++T+I+ AI   ++
Sbjct: 130  LWNYRLLDENGPIDLSNLAALATYSGSLDEAWFYLVTTAIESAGAPSITAIVNAINHIHE 189

Query: 673  GXXXXXXXXXXXXSSTIFDINKTLQKMFKKCDPYVFYWKVRPYLSGWEN--EDRLPKGLI 846
                          +++  +N  LQ+M++KCDPYVFYWK+RPYL+GWEN  E  LP GLI
Sbjct: 190  NNQVALLNDLETIRNSLSTMNDVLQRMYEKCDPYVFYWKIRPYLAGWENMAEAGLPFGLI 249

Query: 847  YDGVDG-----NDE--------NGNPI---YRRYIGGSAGQSALIQALDIALSVKHYPTG 978
            Y+GVD       DE         G  I   YRRY GGSA QS+LI  LD+AL V HYPTG
Sbjct: 250  YEGVDSLWDSETDEYADMSHLSEGERILRQYRRYAGGSAAQSSLIATLDVALGVAHYPTG 309

Query: 979  ---IKPHTNSSCPRYTSCSNGYPQPHDIHQYVSNGHTEPQQP------------------ 1095
                K  T ++         G P P+   +   N   +P  P                  
Sbjct: 310  EKSTKTDTQANDNGVKDRYKGLPTPNPADELHQNNDDQPSTPQIYKKSSAPPFVRTNRNA 369

Query: 1096 YLHRIRQNIPGPHRRFLEDLAKIADIRNYIIXXXXXXXXXXXXXXXXXXXXCLLRETDEA 1275
            +L  +R  +P PHR FLEDL    +IR Y++                         TD  
Sbjct: 370  FLSAMRAYMPRPHREFLEDLETACNIRPYMMQLQEHKHAL----------------TDSE 413

Query: 1276 DDLIKAYNECLNQMKDFR 1329
             DLI+ YNE L+ +K+FR
Sbjct: 414  KDLIRVYNEILSLLKNFR 431


>emb|CDH56721.1| indoleamine-dioxygenase subfamily [Lichtheimia corymbifera
            JMRC:FSU:9682]
          Length = 592

 Score =  345 bits (884), Expect = e-109
 Identities = 192/441 (43%), Positives = 254/441 (57%), Gaps = 42/441 (9%)
 Frame = +1

Query: 133  LEDYDISPSTGFLPSIPPLQCLPDSYYEPWETLISMFHNLMLAGRLREYVKRLPILKTDR 312
            LE+YDISP+TGFLP  PPL+ LPD Y+ PWE+++  F+ L+LAG+LR  V+++P+L   R
Sbjct: 10   LEEYDISPTTGFLPPEPPLRRLPDPYFAPWESMMDDFNGLLLAGKLRRSVEKMPMLDYRR 69

Query: 313  LKTPEEYRRAFLVLSFIAHGYVWGKYETVSDRLPANIAIPWVEVSKYLDVAPIINHAAVV 492
            LKT  EYRRAFLVL  I+H YVWGK+E  S+ LPAN+A+PW  ++ +L + P++ +AAVV
Sbjct: 70   LKTTPEYRRAFLVLCMISHSYVWGKHEKTSETLPANLAVPWTGIANHLGLCPVVCNAAVV 129

Query: 493  TWNWSLLFSDEPFKLNNLATLITFSNTLDESWFYLVTTAIEGFGGRALTSIMAAIQATYD 672
             WN+ LL  D P  L+NLA L T+S +LDESWFYLVTTAIE  G  ++T+I+ AI   ++
Sbjct: 130  LWNYRLLDEDGPIDLSNLAALATYSGSLDESWFYLVTTAIESAGAPSITAIVNAINHIHE 189

Query: 673  GXXXXXXXXXXXXSSTIFDINKTLQKMFKKCDPYVFYWKVRPYLSGWEN--EDRLPKGLI 846
                          +++  +N  LQ+M++KCDPYVFYWK+RPYL+GWEN  E  LP GLI
Sbjct: 190  NNQVALLNDLETIRNSLSTMNDVLQRMYEKCDPYVFYWKIRPYLAGWENMAEAGLPFGLI 249

Query: 847  YDGVDG-----NDENGNPI-----------YRRYIGGSAGQSALIQALDIALSVKHYPTG 978
            Y+GVD       DE  +             YRRY GGSA QS+LI  LD+AL V HYPTG
Sbjct: 250  YEGVDSLWDSETDEYADMSHLSEGERLLRQYRRYAGGSAAQSSLIATLDVALGVAHYPTG 309

Query: 979  IK-PHTNSSCPRYTSCSNGY-----PQPHDIHQYVSNGHTEPQQP--------------- 1095
             K   T  + P  T   + Y     P P D     ++   +P  P               
Sbjct: 310  EKSTKTAGAPPNDTGIKDRYKGLPTPNPADELHQNNDDDQQPSTPQIYKKSSAPPFVRTN 369

Query: 1096 ---YLHRIRQNIPGPHRRFLEDLAKIADIRNYIIXXXXXXXXXXXXXXXXXXXXCLLRET 1266
               +L  +R  +P PHR FLEDL    +IR Y++                         T
Sbjct: 370  RNAFLSAMRAYMPRPHREFLEDLETACNIRPYMMQLQEHKHTL----------------T 413

Query: 1267 DEADDLIKAYNECLNQMKDFR 1329
            D   DLIK YNE L  +K+FR
Sbjct: 414  DNEKDLIKVYNEILGLLKNFR 434


>gb|EPB89940.1| hypothetical protein HMPREF1544_03188 [Mucor circinelloides f.
            circinelloides 1006PhL]
          Length = 588

 Score =  344 bits (882), Expect = e-109
 Identities = 190/438 (43%), Positives = 256/438 (58%), Gaps = 39/438 (8%)
 Frame = +1

Query: 133  LEDYDISPSTGFLPSIPPLQCLPDSYYEPWETLISMFHNLMLAGRLREYVKRLPILKTDR 312
            LE+YDIS  TGFLPS PPL+ L D Y+ PWE ++  F+ L+LAG+LRE V ++P+L    
Sbjct: 13   LEEYDISVKTGFLPSTPPLRRLSDPYFAPWEEMMDDFNGLLLAGKLREKVHKMPLLDHTH 72

Query: 313  LKTPEEYRRAFLVLSFIAHGYVWGKYETVSDRLPANIAIPWVEVSKYLDVAPIINHAAVV 492
            LK+ EEYRRAFL+L  ++H YVWGK+ET S+ LP+N+AIPW  ++ +L + P++ HAAVV
Sbjct: 73   LKSVEEYRRAFLILCMVSHSYVWGKHETTSETLPSNLAIPWTSIADHLGLCPVVCHAAVV 132

Query: 493  TWNWSLLFSDEPFKLNNLATLITFSNTLDESWFYLVTTAIEGFGGRALTSIMAAIQATYD 672
             WN+ LL  + P  L+NLA L T+S +LDESWFYL+TTAIE  G   L+ I  AI   + 
Sbjct: 133  LWNYRLLDKEGPIDLSNLAALATYSGSLDESWFYLITTAIESSGAPCLSQITYAIDNIHQ 192

Query: 673  GXXXXXXXXXXXXSSTIFDINKTLQKMFKKCDPYVFYWKVRPYLSGWEN--EDRLPKGLI 846
            G             + + ++N  L++M++KCDPYVFYWK+RPYL+GWEN  E  LP GLI
Sbjct: 193  GKYGDLKQNLETIRTALANMNDDLKRMYEKCDPYVFYWKIRPYLAGWENMAEAGLPLGLI 252

Query: 847  YDGVDG-----NDENGN-----------PIYRRYIGGSAGQSALIQALDIALSVKHYPTG 978
            Y+GVD       DE  +             YRRY GGSA QS+LI ALD+A  V+H+ TG
Sbjct: 253  YEGVDSLWNAQTDEYADMSHLDEAERLLSQYRRYAGGSAAQSSLIAALDVAFGVEHHRTG 312

Query: 979  IKPHTNSSC----PRYTSCSNGYPQPHDIHQYVSNGHTEPQQP----------YLHRIRQ 1116
             KP    +      RYT      P        ++NG   P+ P          +L  +R+
Sbjct: 313  EKPSFIKAADLPNDRYTKLPATNPADE-----INNGAETPRTPPRFKRTNRNTFLRAMRK 367

Query: 1117 NIPGPHRRFLEDLAKIADIRNYIIXXXXXXXXXXXXXXXXXXXXCLLRETD-------EA 1275
             +P PHR FLEDL + A+IR YI+                      L E D       E 
Sbjct: 368  YMPRPHREFLEDLEEAANIRPYILQ---------------------LEENDKNGNISAEE 406

Query: 1276 DDLIKAYNECLNQMKDFR 1329
             +++KAYN+CL+Q+K FR
Sbjct: 407  LEIVKAYNDCLHQLKLFR 424


>dbj|GAN01973.1| indoleamine 2,3-dioxygenase subfamily [Mucor ambiguus]
          Length = 591

 Score =  344 bits (882), Expect = e-109
 Identities = 188/431 (43%), Positives = 255/431 (59%), Gaps = 32/431 (7%)
 Frame = +1

Query: 133  LEDYDISPSTGFLPSIPPLQCLPDSYYEPWETLISMFHNLMLAGRLREYVKRLPILKTDR 312
            L DYDIS  TGFLPS PPL+ L D Y+  WE ++  F+ L+LAG+LRE V+++P+L   +
Sbjct: 15   LGDYDISIKTGFLPSTPPLRRLSDPYFSSWEEMMDDFNGLLLAGKLREKVQKMPLLDHTK 74

Query: 313  LKTPEEYRRAFLVLSFIAHGYVWGKYETVSDRLPANIAIPWVEVSKYLDVAPIINHAAVV 492
            LK+ EEYRRAFL+L  ++H YVWGK+ET S+ LP+N+AIPW  ++++L + P++ HAAVV
Sbjct: 75   LKSVEEYRRAFLILCMVSHSYVWGKHETTSETLPSNLAIPWTSIAEHLGLCPVVCHAAVV 134

Query: 493  TWNWSLLFSDEPFKLNNLATLITFSNTLDESWFYLVTTAIEGFGGRALTSIMAAIQATYD 672
             WN+ LL  + P  L+NLA L T+S +LDESWFYLVTTAIE  G   L+ I  AI   + 
Sbjct: 135  LWNYRLLDKEGPIDLSNLAALATYSGSLDESWFYLVTTAIESSGAPCLSQITYAIDNIHQ 194

Query: 673  GXXXXXXXXXXXXSSTIFDINKTLQKMFKKCDPYVFYWKVRPYLSGWEN--EDRLPKGLI 846
            G             + + ++N  L++M++KCDPYVFYWK+RPYL+GWEN  E  LP GLI
Sbjct: 195  GKYGDLKQNLETIRTALANMNDDLKRMYEKCDPYVFYWKIRPYLAGWENMAEAGLPLGLI 254

Query: 847  YDGVDG-----NDENGN-----------PIYRRYIGGSAGQSALIQALDIALSVKHYPTG 978
            Y+GVD       DE  +             YRRY GGSA QS+LI ALD+A  V+H+ TG
Sbjct: 255  YEGVDALWNAQTDEYADMSHLDEAERLLSQYRRYAGGSAAQSSLIAALDVAFGVEHHRTG 314

Query: 979  IKPHTNSSC----PRYTSCSNGYPQPHDIHQYVSNGHTEPQQP----------YLHRIRQ 1116
             KP    +      RYT      P        ++NG   P+ P          +L  +R+
Sbjct: 315  EKPSFIKAADLPNDRYTKLPATNPADE-----INNGAETPRTPPRFKRTNRNTFLRAMRK 369

Query: 1117 NIPGPHRRFLEDLAKIADIRNYIIXXXXXXXXXXXXXXXXXXXXCLLRETDEADDLIKAY 1296
             +P PHR FLEDL + A+IR YI+                         T E  +++KAY
Sbjct: 370  YMPRPHREFLEDLEEAANIRPYILQLEENDKNGSI--------------TTEELEIVKAY 415

Query: 1297 NECLNQMKDFR 1329
            N+CL+Q+K FR
Sbjct: 416  NDCLHQLKLFR 426


>gb|OAQ23912.1| Indoleamine 2,3-dioxygenase [Mortierella elongata AG-77]
          Length = 519

 Score =  340 bits (873), Expect = e-109
 Identities = 177/405 (43%), Positives = 238/405 (58%), Gaps = 3/405 (0%)
 Frame = +1

Query: 124  VPRLEDYDISPSTGFLPSIPPLQCLPDSYYEPWETLISMFHNLMLAGRLREYVKRLPILK 303
            +P L +YDISP TGFLP   PLQ LPD Y+ PWE     F+ L+LA RLR+YV  LP+L 
Sbjct: 9    LPVLSEYDISPITGFLPVEEPLQVLPDPYFAPWEETFQKFNGLLLASRLRQYVNELPVLD 68

Query: 304  TDRLKTPEEYRRAFLVLSFIAHGYVWGKYETVSDRLPANIAIPWVEVSKYLDVAPIINHA 483
              +LKT  E RR +L+L  ++H YVWGK+E  ++ LPA +A+PW +V+  L++ P++ HA
Sbjct: 69   AAKLKTKAEQRRGYLILCMLSHAYVWGKHEQAAEVLPAALAVPWQKVADMLEMQPVLTHA 128

Query: 484  AVVTWNWSLLFSDEPFKLNNLATLITFSNTLDESWFYLVTTAIEGFGGRALTSIMAAIQA 663
            AVV WNW LL+ D P  LNNL TL T S + DESWFYLVTTAIE  G   L+ I+ AIQ 
Sbjct: 129  AVVMWNWRLLYKDGPRDLNNLDTLGTLSGSSDESWFYLVTTAIEATGAPVLSKILTAIQQ 188

Query: 664  TYDGXXXXXXXXXXXXSSTIFDINKTLQKMFKKCDPYVFYWKVRPYLSGWEN--EDRLPK 837
              D                I D+   L++MF++CDPYVFYWKVRPYL+GWEN  E  LP 
Sbjct: 189  ARDNNIVGLTQELEGIRGIIEDLVSVLRRMFERCDPYVFYWKVRPYLAGWENMAEAGLPN 248

Query: 838  GLIYDGVDGNDENGNPIYRRYIGGSAGQSALIQALDIALSVKHYPTGIKPH-TNSSCPRY 1014
            G+ Y+GVD  +      Y++  GGSA QS+LI ALDIA  V+H+PTG +PH   +S P  
Sbjct: 249  GVRYEGVDNGE------YKKLAGGSAAQSSLIHALDIAFGVEHHPTGFRPHKAGASAP-- 300

Query: 1015 TSCSNGYPQPHDIHQYVSNGHTEPQQPYLHRIRQNIPGPHRRFLEDLAKIADIRNYIIXX 1194
               + G P  H      +         ++ ++R  +PGPHR FL  L ++++IR ++   
Sbjct: 301  ---ATGSPAVHPPSAATAAPAAVKPTNFIQKMRFYMPGPHRSFLTHLTEVSNIRQFVTEK 357

Query: 1195 XXXXXXXXXXXXXXXXXXCLLRETDEADDLIKAYNECLNQMKDFR 1329
                                   T E + LI  Y+EC++Q+K FR
Sbjct: 358  AAG------------------ERTAEVEKLITVYDECVHQIKVFR 384


>emb|CEG75499.1| hypothetical protein RMATCC62417_10531 [Rhizopus microsporus]
          Length = 549

 Score =  336 bits (862), Expect = e-107
 Identities = 185/433 (42%), Positives = 251/433 (57%), Gaps = 28/433 (6%)
 Frame = +1

Query: 115  TFNVPRLEDYDISPSTGFLPSIPPLQCLPDSYYEPWETLISMFHNLMLAGRLREYVKRLP 294
            T  +  LEDYDISP TGFLPS PPL+ L D Y+ PWE ++  F+ L+LAGRLRE +  LP
Sbjct: 2    TLTMRPLEDYDISPVTGFLPSKPPLKRLTDEYFAPWENMMDNFNGLLLAGRLREKIHELP 61

Query: 295  ILKTDRLKTPEEYRRAFLVLSFIAHGYVWGKYETVSDRLPANIAIPWVEVSKYLDVAPII 474
            +L  ++L + EEYRRAFL+L  ++H YVWGK E  S+ LP+ +A+PW +++ +L + P++
Sbjct: 62   LLDANKLGSIEEYRRAFLILCLLSHAYVWGKLELASETLPSQLAVPWTKIADHLGLCPVV 121

Query: 475  NHAAVVTWNWSLLFSDEPFKLNNLATLITFSNTLDESWFYLVTTAIEGFGGRALTSIMAA 654
             HAAV  WN+ LL  D P  L+NLA + T+S +LDE+WFYLVTT+IE  G   ++ IMAA
Sbjct: 122  CHAAVALWNYRLLDEDGPIDLSNLAIMGTYSGSLDEAWFYLVTTSIESAGAPCVSQIMAA 181

Query: 655  IQATYDGXXXXXXXXXXXXSSTIFDINKTLQKMFKKCDPYVFYWKVRPYLSGWEN--EDR 828
            I    DG              +I ++   L +M++KCDPYVFYWK+RPYL+GWEN  E  
Sbjct: 182  IDNIQDGNYAGLKANLETIRDSIAEMTHVLTRMYEKCDPYVFYWKIRPYLAGWENMAEAG 241

Query: 829  LPKGLIYDGVDGNDENGNPI---------------YRRYIGGSAGQSALIQALDIALSVK 963
            LP GLIY+GVD   E  +                 YRRY GGSA QS+LI ALD+A  V+
Sbjct: 242  LPLGLIYEGVDLWSEQTDEYADMSHLDSAQRLLRQYRRYAGGSAAQSSLIAALDVAFGVE 301

Query: 964  HYPTGIKP----HTNSSCPRYTSCSNGYPQPHD-IHQYVSNGHTEPQ------QPYLHRI 1110
            H+ TG KP     +     RYT      P P D ++       T PQ        +L  +
Sbjct: 302  HHRTGEKPTVIKPSELPADRYTKLP--APNPADELNGSAETPRTPPQFKRTNHNAFLRAM 359

Query: 1111 RQNIPGPHRRFLEDLAKIADIRNYIIXXXXXXXXXXXXXXXXXXXXCLLRETDEADDLIK 1290
            R+ +P  HR FLEDL   A+IR +I+                         T+E  +L++
Sbjct: 360  RKYMPRSHREFLEDLEVAANIRPFILHLEEQHRQGAI--------------TEEEIELVE 405

Query: 1291 AYNECLNQMKDFR 1329
             YN+CL+Q+K FR
Sbjct: 406  MYNQCLHQLKLFR 418


>emb|CEP11056.1| hypothetical protein [Parasitella parasitica]
          Length = 595

 Score =  337 bits (865), Expect = e-107
 Identities = 185/431 (42%), Positives = 249/431 (57%), Gaps = 32/431 (7%)
 Frame = +1

Query: 133  LEDYDISPSTGFLPSIPPLQCLPDSYYEPWETLISMFHNLMLAGRLREYVKRLPILKTDR 312
            L++YDIS  TGFLP  PPL+ L D Y+ PWE ++  F+ L+LAG+LRE V ++P+L   +
Sbjct: 13   LDEYDISVKTGFLPPTPPLRRLSDPYFAPWEDMMDDFNGLLLAGKLREKVHKMPLLDYSK 72

Query: 313  LKTPEEYRRAFLVLSFIAHGYVWGKYETVSDRLPANIAIPWVEVSKYLDVAPIINHAAVV 492
            L+  EEYRRAFL+L  ++H YVWGK+E  S+ LP+N+AIPW  ++ +L + P++ HAAVV
Sbjct: 73   LQLVEEYRRAFLILCMVSHSYVWGKHEATSETLPSNLAIPWTGIADHLGLCPVVCHAAVV 132

Query: 493  TWNWSLLFSDEPFKLNNLATLITFSNTLDESWFYLVTTAIEGFGGRALTSIMAAIQATYD 672
             WN+ LL  D P  L N+A L T+S +LDESWFYL+TTAIE  G   L+ I +AI     
Sbjct: 133  LWNYRLLDKDGPIDLGNMAALATYSGSLDESWFYLITTAIESSGAPCLSQITSAIDNIEQ 192

Query: 673  GXXXXXXXXXXXXSSTIFDINKTLQKMFKKCDPYVFYWKVRPYLSGWEN--EDRLPKGLI 846
            G             S +  +N  L++M++KCDPYVFYWK+RPYL+GWEN  E  LP GLI
Sbjct: 193  GKYSELKQNLETICSALASMNDDLKRMYEKCDPYVFYWKIRPYLAGWENMAEAGLPLGLI 252

Query: 847  YDGVDG-----NDENGNPI-----------YRRYIGGSAGQSALIQALDIALSVKHYPTG 978
            Y+GVD       DE  +             YRRY GGSA QS+LI ALD+A  V+H+ TG
Sbjct: 253  YEGVDSLWNAQTDEYADMSHLDEAERLLNQYRRYAGGSAAQSSLIAALDVAFGVEHHRTG 312

Query: 979  IKPHTNSSC----PRYTSCSNGYPQPHDIHQYVSNGHTEPQQP----------YLHRIRQ 1116
             KP    +      RYT      P        ++NG   P+ P          +L  +R+
Sbjct: 313  EKPSFIKAADLPNDRYTKLPATNPADE-----INNGAETPRTPPRFKRTNRNTFLRAMRK 367

Query: 1117 NIPGPHRRFLEDLAKIADIRNYIIXXXXXXXXXXXXXXXXXXXXCLLRETDEADDLIKAY 1296
             +P PHR FLEDL + A+IR YI+                         T E  +++ AY
Sbjct: 368  YMPRPHREFLEDLEEAANIRPYILQLQENDKNGSI--------------TLEELEIVSAY 413

Query: 1297 NECLNQMKDFR 1329
            NECL+Q+K FR
Sbjct: 414  NECLHQLKLFR 424


>gb|ORE18396.1| Indoleamine 2,3-dioxygenase [Rhizopus microsporus]
          Length = 549

 Score =  336 bits (861), Expect = e-106
 Identities = 184/433 (42%), Positives = 252/433 (58%), Gaps = 28/433 (6%)
 Frame = +1

Query: 115  TFNVPRLEDYDISPSTGFLPSIPPLQCLPDSYYEPWETLISMFHNLMLAGRLREYVKRLP 294
            T  +  LEDYDISP TGFLPS PPL+ L + Y+ PWE ++  F+ L+LAGRLRE ++ LP
Sbjct: 2    TLTMRPLEDYDISPVTGFLPSKPPLKRLTNEYFAPWENMMDNFNGLLLAGRLREKIQELP 61

Query: 295  ILKTDRLKTPEEYRRAFLVLSFIAHGYVWGKYETVSDRLPANIAIPWVEVSKYLDVAPII 474
            +L  +RL + EEYRRAFL+L  ++H YVWGK E  S+ LP+ +A+PW +++ +L + P++
Sbjct: 62   LLDANRLGSIEEYRRAFLILCLLSHAYVWGKLELASETLPSQLAVPWTKIADHLGLCPVV 121

Query: 475  NHAAVVTWNWSLLFSDEPFKLNNLATLITFSNTLDESWFYLVTTAIEGFGGRALTSIMAA 654
             HAAV  WN+ LL  D P  L+NLA + T+S +LDE+WFYLVTT+IE  G   ++ IMAA
Sbjct: 122  CHAAVALWNYRLLDEDGPIDLSNLAIMGTYSGSLDEAWFYLVTTSIESAGAPCISQIMAA 181

Query: 655  IQATYDGXXXXXXXXXXXXSSTIFDINKTLQKMFKKCDPYVFYWKVRPYLSGWEN--EDR 828
            I    DG              +I ++   L +M++KCDPYVFYWK+RPYL+GWEN  E  
Sbjct: 182  IDNIQDGNYTGLKANLETIRDSIAEMTHVLTRMYEKCDPYVFYWKIRPYLAGWENMAEAG 241

Query: 829  LPKGLIYDGVDGNDENGNPI---------------YRRYIGGSAGQSALIQALDIALSVK 963
            LP GLIY+GVD   E  +                 YRRY GGSA QS+LI ALD+A  V+
Sbjct: 242  LPLGLIYEGVDLWSEQTDEYADMSHLDSAQRLLRQYRRYAGGSAAQSSLIAALDVAFGVE 301

Query: 964  HYPTGIKP----HTNSSCPRYTSCSNGYPQPHD-IHQYVSNGHTEPQ------QPYLHRI 1110
            H+ TG KP     +     RYT      P P D ++       T PQ        +L  +
Sbjct: 302  HHRTGEKPTVIKPSELPADRYTKLP--APNPADELNGSAETPRTPPQFKRTNHNAFLRAM 359

Query: 1111 RQNIPGPHRRFLEDLAKIADIRNYIIXXXXXXXXXXXXXXXXXXXXCLLRETDEADDLIK 1290
            R+ +P  HR FLEDL   A+IR +++                         T+E  +L++
Sbjct: 360  RKYMPRSHREFLEDLEVAANIRPFMLQLEEQHRQGAI--------------TEEEIELVE 405

Query: 1291 AYNECLNQMKDFR 1329
             YN+CL+Q+K FR
Sbjct: 406  VYNQCLHQLKLFR 418


>ref|XP_023463810.1| Indoleamine 2,3-dioxygenase [Rhizopus microsporus ATCC 52813]
 gb|PHZ10102.1| Indoleamine 2,3-dioxygenase [Rhizopus microsporus ATCC 52813]
          Length = 549

 Score =  335 bits (860), Expect = e-106
 Identities = 184/433 (42%), Positives = 252/433 (58%), Gaps = 28/433 (6%)
 Frame = +1

Query: 115  TFNVPRLEDYDISPSTGFLPSIPPLQCLPDSYYEPWETLISMFHNLMLAGRLREYVKRLP 294
            T  +  LEDYDISP TGFLPS PPL+ L + Y+ PWE ++  F+ L+LAGRLRE +  LP
Sbjct: 2    TLTMRPLEDYDISPVTGFLPSKPPLKRLTNEYFAPWENMMDNFNGLLLAGRLREKIHELP 61

Query: 295  ILKTDRLKTPEEYRRAFLVLSFIAHGYVWGKYETVSDRLPANIAIPWVEVSKYLDVAPII 474
            +L  +RL + EEYRRAFL+L  ++H YVWGK E  S+ LP+ +A+PW +++ +L + P++
Sbjct: 62   LLDANRLGSIEEYRRAFLILCLLSHAYVWGKLELASETLPSQLAVPWTKIADHLGLCPVV 121

Query: 475  NHAAVVTWNWSLLFSDEPFKLNNLATLITFSNTLDESWFYLVTTAIEGFGGRALTSIMAA 654
             HAAV  WN+ LL  D P  L+NLA + T+S +LDE+WFYLVTT+IE  G   ++ IMAA
Sbjct: 122  CHAAVALWNYRLLDEDGPIDLSNLAIMGTYSGSLDEAWFYLVTTSIESAGAPCVSQIMAA 181

Query: 655  IQATYDGXXXXXXXXXXXXSSTIFDINKTLQKMFKKCDPYVFYWKVRPYLSGWEN--EDR 828
            I    DG              +I ++ + L +M++KCDPYVFYWK+RPYL+GWEN  E  
Sbjct: 182  IDNIQDGNYTGLKANLETIRDSIAEMTQVLTRMYEKCDPYVFYWKIRPYLAGWENMAEAG 241

Query: 829  LPKGLIYDGVDGNDENGNPI---------------YRRYIGGSAGQSALIQALDIALSVK 963
            LP GLIY+GVD   E  +                 YRRY GGSA QS+LI ALD+A  V+
Sbjct: 242  LPLGLIYEGVDLWSEQTDEYADMSHLDSAQRLLRQYRRYAGGSAAQSSLIAALDVAFGVE 301

Query: 964  HYPTGIKP----HTNSSCPRYTSCSNGYPQPHD-IHQYVSNGHTEPQ------QPYLHRI 1110
            H+ TG KP     +     RYT      P P D ++       T PQ        +L  +
Sbjct: 302  HHRTGEKPTVIKPSELPADRYTKLP--APNPADELNGSAETPRTPPQFKRTNHNAFLRAM 359

Query: 1111 RQNIPGPHRRFLEDLAKIADIRNYIIXXXXXXXXXXXXXXXXXXXXCLLRETDEADDLIK 1290
            R+ +P  HR FLEDL   A+IR +++                         T+E  +L++
Sbjct: 360  RKYMPRSHREFLEDLEVAANIRPFMLQLEEQHRQGTI--------------TEEEIELVE 405

Query: 1291 AYNECLNQMKDFR 1329
             YN+CL+Q+K FR
Sbjct: 406  VYNQCLHQLKLFR 418


>gb|ORE11191.1| Indoleamine 2,3-dioxygenase [Rhizopus microsporus var. microsporus]
          Length = 549

 Score =  335 bits (860), Expect = e-106
 Identities = 184/433 (42%), Positives = 252/433 (58%), Gaps = 28/433 (6%)
 Frame = +1

Query: 115  TFNVPRLEDYDISPSTGFLPSIPPLQCLPDSYYEPWETLISMFHNLMLAGRLREYVKRLP 294
            T  +  LEDYDISP TGFLPS PPL+ L + Y+ PWE ++  F+ L+LAGRLRE +  LP
Sbjct: 2    TLTMRPLEDYDISPVTGFLPSKPPLKRLTNEYFAPWENMMDNFNGLLLAGRLREKIHELP 61

Query: 295  ILKTDRLKTPEEYRRAFLVLSFIAHGYVWGKYETVSDRLPANIAIPWVEVSKYLDVAPII 474
            +L  +RL + EEYRRAFL+L  ++H YVWGK E  S+ LP+ +A+PW +++ +L + P++
Sbjct: 62   LLDANRLGSIEEYRRAFLILCLLSHAYVWGKLELASETLPSQLAVPWTKIADHLGLCPVV 121

Query: 475  NHAAVVTWNWSLLFSDEPFKLNNLATLITFSNTLDESWFYLVTTAIEGFGGRALTSIMAA 654
             HAAV  WN+ LL  D P  L+NLA + T+S +LDE+WFYLVTT+IE  G   ++ IMAA
Sbjct: 122  CHAAVALWNYRLLDEDGPIDLSNLAIMGTYSGSLDEAWFYLVTTSIESAGAPCVSQIMAA 181

Query: 655  IQATYDGXXXXXXXXXXXXSSTIFDINKTLQKMFKKCDPYVFYWKVRPYLSGWEN--EDR 828
            I    DG              +I ++ + L +M++KCDPYVFYWK+RPYL+GWEN  E  
Sbjct: 182  IDNIQDGNYTGLKSNLETIRDSIAEMTQVLTRMYEKCDPYVFYWKIRPYLAGWENMAEAG 241

Query: 829  LPKGLIYDGVDGNDENGNPI---------------YRRYIGGSAGQSALIQALDIALSVK 963
            LP GLIY+GVD   E  +                 YRRY GGSA QS+LI ALD+A  V+
Sbjct: 242  LPLGLIYEGVDLWSEQTDEYADMSHLDSAQRLLRQYRRYAGGSAAQSSLIAALDVAFGVE 301

Query: 964  HYPTGIKP----HTNSSCPRYTSCSNGYPQPHD-IHQYVSNGHTEPQ------QPYLHRI 1110
            H+ TG KP     +     RYT      P P D ++       T PQ        +L  +
Sbjct: 302  HHRTGEKPTVIKPSELPADRYTKLP--APNPADELNGSAETPRTPPQFKRTNHNAFLRAM 359

Query: 1111 RQNIPGPHRRFLEDLAKIADIRNYIIXXXXXXXXXXXXXXXXXXXXCLLRETDEADDLIK 1290
            R+ +P  HR FLEDL   A+IR +++                         T+E  +L++
Sbjct: 360  RKYMPRSHREFLEDLEVAANIRPFMLQLEEQHRQGTI--------------TEEEIELVE 405

Query: 1291 AYNECLNQMKDFR 1329
             YN+CL+Q+K FR
Sbjct: 406  VYNQCLHQLKLFR 418


>gb|EIE92414.1| hypothetical protein RO3G_16936 [Rhizopus delemar RA 99-880]
 dbj|BAO42879.1| indoleamine 2,3-dioxygenase isoform I [Rhizopus delemar]
          Length = 553

 Score =  335 bits (860), Expect = e-106
 Identities = 185/427 (43%), Positives = 253/427 (59%), Gaps = 28/427 (6%)
 Frame = +1

Query: 133  LEDYDISPSTGFLPSIPPLQCLPDSYYEPWETLISMFHNLMLAGRLREYVKRLPILKTDR 312
            LE YD+SP TGFLPS PPL+ L + Y+ PWE ++  F++L+LAG+LRE + +LP+L + R
Sbjct: 8    LEKYDVSPITGFLPSTPPLKRLSNEYFAPWENMMDDFNDLLLAGKLREKIHKLPLLDSRR 67

Query: 313  LKTPEEYRRAFLVLSFIAHGYVWGKYETVSDRLPANIAIPWVEVSKYLDVAPIINHAAVV 492
            L+T EEYRRAFL++  ++H YVWGK E  S+ LPA +AIPW  ++ +L + P++ HAAVV
Sbjct: 68   LQTIEEYRRAFLIMCMLSHSYVWGKLEQASESLPAQLAIPWTNIADHLGLCPVVCHAAVV 127

Query: 493  TWNWSLLFSDEPFKLNNLATLITFSNTLDESWFYLVTTAIEGFGGRALTSIMAAIQATYD 672
             WN+ +L  DEP  LNN+  L T+S +LDE+WFYLVT +IE  G   L+ I++AI    D
Sbjct: 128  LWNYRMLDQDEPLDLNNIGALATYSGSLDEAWFYLVTASIEITGAPCLSQIVSAIDNIRD 187

Query: 673  GXXXXXXXXXXXXSSTIFDINKTLQKMFKKCDPYVFYWKVRPYLSGWEN--EDRLPKGLI 846
            G              ++  +N +L +M++KCDPYVFYWK+RPYL+GWEN  E  LP GLI
Sbjct: 188  GNYSGLKLNLETIRDSLVQMNASLMRMYEKCDPYVFYWKIRPYLAGWENMAEAGLPLGLI 247

Query: 847  YDGVDGNDENGNPI---------------YRRYIGGSAGQSALIQALDIALSVKHYPTGI 981
            Y+GVD   E  +                 YRRY GGSA QS+LI ALDIA  V+H+ TG 
Sbjct: 248  YEGVDLWSEQTDEYADMSHLDDAQRLLRQYRRYAGGSAAQSSLIAALDIAFGVEHHRTGE 307

Query: 982  KP----HTNSSCPRYTSCSNGYPQPHD-IHQYVSNGHTEPQ------QPYLHRIRQNIPG 1128
            KP     +     RYT      P P D ++    +  T PQ        +L  +R+ +P 
Sbjct: 308  KPLVVKPSELPVDRYTKLP--APNPADELNGTAESPRTPPQFKRTNRNTFLRAMRKYMPR 365

Query: 1129 PHRRFLEDLAKIADIRNYIIXXXXXXXXXXXXXXXXXXXXCLLRETDEADDLIKAYNECL 1308
            PHR FLE+L   A+IR +I+                     LL E  +   LI+ YNEC+
Sbjct: 366  PHREFLEELEIAANIRPFIL-----------QLEEQLRSGALLPEEAQ---LIETYNECI 411

Query: 1309 NQMKDFR 1329
            +Q+K FR
Sbjct: 412  HQLKLFR 418


>ref|XP_021883366.1| Indoleamine 2,3-dioxygenase [Lobosporangium transversale]
 gb|ORZ22812.1| Indoleamine 2,3-dioxygenase [Lobosporangium transversale]
          Length = 545

 Score =  335 bits (859), Expect = e-106
 Identities = 182/416 (43%), Positives = 248/416 (59%), Gaps = 14/416 (3%)
 Frame = +1

Query: 124  VPRLEDYDISPSTGFLPSIPPLQCLPDSYYEPWETLISMFHNLMLAGRLREYVKRLPILK 303
            +P LEDYDISP TGFLP   PL+ L D Y+ PWE    +F+ L+LA R+R++V+ LPIL 
Sbjct: 6    LPILEDYDISPVTGFLPVDEPLEVLSDPYFAPWEETFKIFNGLLLASRIRQHVQDLPILD 65

Query: 304  TDRLKTPEEYRRAFLVLSFIAHGYVWGKYETVSDRLPANIAIPWVEVSKYLDVAPIINHA 483
              RLKT  E RRA+L+L  ++H +VWGK+E  ++ LPA++A+PW +V+  L++ P++ HA
Sbjct: 66   ASRLKTKAEQRRAYLILCMLSHAFVWGKHEIAAESLPASLAVPWQKVADMLEIQPVLTHA 125

Query: 484  AVVTWNWSLLFSDEPFKLNNLATLITFSNTLDESWFYLVTTAIEGFGGRALTSIMAAIQA 663
            AVV WNW LL+ D P  L+NL TL T S + DESWFYLVTTAIE  G  AL+ I+ AIQ 
Sbjct: 126  AVVLWNWRLLYKDGPRDLSNLDTLGTLSGSSDESWFYLVTTAIEATGAPALSKILKAIQL 185

Query: 664  TYDGXXXXXXXXXXXXSSTIFDINKTLQKMFKKCDPYVFYWKVRPYLSGWEN--EDRLPK 837
              D                I  +   L++MF++CDPYVFYWKVRPYL+GWEN  E  LP 
Sbjct: 186  VRDDNISGLTEELTAIRGIIESLVAVLRRMFERCDPYVFYWKVRPYLAGWENMAEAGLPN 245

Query: 838  GLIYDGVDGNDENGNPIYRRYIGGSAGQSALIQALDIALSVKHYPTGIKPHTNSSCPRYT 1017
            G+ Y+GVD    +GN  Y++  GGSA QS+LI ALDIA  V+HYPTG +P+  +     T
Sbjct: 246  GVRYEGVD----DGN--YKKLAGGSAAQSSLIHALDIAFGVEHYPTGFRPNKATG----T 295

Query: 1018 SCSNGYPQPHDIHQYVS--------NGHT----EPQQPYLHRIRQNIPGPHRRFLEDLAK 1161
              +NG   PH+ +  VS        NG           ++ ++R  +PGPHR FL  L +
Sbjct: 296  ITANGV--PHNSYNDVSAPTPGTKANGAPASAGSGSTNFIQKMRFYMPGPHRNFLTHLTE 353

Query: 1162 IADIRNYIIXXXXXXXXXXXXXXXXXXXXCLLRETDEADDLIKAYNECLNQMKDFR 1329
            +A+IR Y+                            + + LI  Y+EC++Q+K FR
Sbjct: 354  VANIRQYVTTKAAASEKG--------------SRPADVEQLITVYDECVHQIKVFR 395


>gb|KXN71802.1| Indoleamine 2,3-dioxygenase [Conidiobolus coronatus NRRL 28638]
          Length = 529

 Score =  332 bits (850), Expect = e-105
 Identities = 171/362 (47%), Positives = 230/362 (63%), Gaps = 8/362 (2%)
 Frame = +1

Query: 124  VPRLEDYDISPSTGFLPSIPPLQCLPDSYYEPWETLISMFHNLMLAGRLREYVKRLPILK 303
            +PRL+DYDI P  GFLP+ PPL  LPDSYY+PWE +I+ F++L+L G+LRE V +LP+L+
Sbjct: 10   LPRLQDYDIDPHNGFLPATPPLSKLPDSYYQPWEDIINNFNSLLLIGKLRERVLKLPLLE 69

Query: 304  TDRLKTPEEYRRAFLVLSFIAHGYVWGKYETVSDRLPANIAIPWVEVSKYLDVAPIINHA 483
             DRL+T +EY+RA+ +L FI H Y+WGK E V + LPA IA+P+ ++S YL + P++++A
Sbjct: 70   VDRLQTLKEYQRAYTILGFITHAYIWGKNEPVKEVLPACIAVPFCKISDYLGLPPVMSYA 129

Query: 484  AVVTWNWSLLFSDEPFKLNNLATLITFSNTLDESWFYLVTTAIEGFGGRALTSIMAAIQA 663
            +   WNW LL  +EP  ++N+    T+S + DE WFYL++  IE FGG+AL +++ AIQA
Sbjct: 130  SSAMWNWHLLDPNEPINVDNIVMTYTYSGSTDEMWFYLISVQIEHFGGKALDNMIKAIQA 189

Query: 664  TYDGXXXXXXXXXXXXSSTIFDINKTLQKMFKKCDPYVFYWKVRPYLSGWENEDR--LPK 837
              +             +  I DINKTL KM +KCDPYVFYWKVRPYL+GWEN     LP 
Sbjct: 190  AQNWDLEGLSKNLAAIADAITDINKTLIKMHEKCDPYVFYWKVRPYLAGWENMQNAGLPH 249

Query: 838  GLIYDGVD-----GNDENGNPI-YRRYIGGSAGQSALIQALDIALSVKHYPTGIKPHTNS 999
            G+IY+GVD      N E  +P  YR+Y GGSAGQS+LIQALD+ L V HYPT  +     
Sbjct: 250  GIIYEGVDCPAPVTNPEEVSPSKYRQYAGGSAGQSSLIQALDVFLGVNHYPTSSEWREWK 309

Query: 1000 SCPRYTSCSNGYPQPHDIHQYVSNGHTEPQQPYLHRIRQNIPGPHRRFLEDLAKIADIRN 1179
              P                 Y  + H      YL +IR  +P  HR+FL DL +  DIR 
Sbjct: 310  KNPEL---------------YNPSKHVN----YLMKIRDYMPNLHRQFLYDLKEAFDIRA 350

Query: 1180 YI 1185
            +I
Sbjct: 351  FI 352


>ref|XP_019023834.1| Indoleamine 2,3-dioxygenase, partial [Saitoella complicata NRRL
            Y-17804]
 gb|ODQ52721.1| Indoleamine 2,3-dioxygenase, partial [Saitoella complicata NRRL
            Y-17804]
          Length = 430

 Score =  327 bits (839), Expect = e-105
 Identities = 178/405 (43%), Positives = 237/405 (58%), Gaps = 2/405 (0%)
 Frame = +1

Query: 121  NVPRLEDYDISPSTGFLPSIPPLQCLPDSYYEPWETLISMFHNLMLAGRLREYVKRLPIL 300
            ++P L DY +SP TGFLP+  PL  L D YYEPWE ++  ++  +LAGRLRE V  LP L
Sbjct: 4    SIPDLADYGLSPETGFLPASAPLARLTDPYYEPWERIMDSYNGYLLAGRLREVVHALPEL 63

Query: 301  KTDRLKTPEEYRRAFLVLSFIAHGYVWGKYETVSDRLPANIAIPWVEVSKYLDVAPIINH 480
             T+ L    + RRAF+VL FIAHGYVWG  + + +RLP  +A+PWV+V+  L+V P++ H
Sbjct: 64   STEYLHNVRDLRRAFVVLCFIAHGYVWGGAQPM-ERLPRQLAVPWVQVANALEVRPVVCH 122

Query: 481  AAVVTWNWSLLFSDEPFKLNNLATLITFSNTLDESWFYLVTTAIEGFGGRALTSIMAAIQ 660
            AAV  WN+  LF DEP  L NLAT  TFS  +DESWFYL+TTAIE  GG  +  ++ A+Q
Sbjct: 123  AAVCLWNYKPLFFDEPLDLENLATFHTFSGAMDESWFYLITTAIEARGGPCMPLLLDAMQ 182

Query: 661  ATYDGXXXXXXXXXXXXSSTIFDINKTLQKMFKKCDPYVFYWKVRPYLSGWEN--EDRLP 834
            A  +             +  +  +N  L +M++KCDPYVFYWKVRPYL+GW N  E  LP
Sbjct: 183  AAREDDKVRFVDNLRTLAVQLDGLNDALARMYEKCDPYVFYWKVRPYLAGWNNMAEAGLP 242

Query: 835  KGLIYDGVDGNDENGNPIYRRYIGGSAGQSALIQALDIALSVKHYPTGIKPHTNSSCPRY 1014
             G+IY+G D  +EN    YR+Y GGSA QSALI ALDIAL V+H PTG K  T    PR 
Sbjct: 243  NGVIYEGCD--EENH---YRKYAGGSAAQSALIHALDIALGVEHRPTGEKKDT----PRQ 293

Query: 1015 TSCSNGYPQPHDIHQYVSNGHTEPQQPYLHRIRQNIPGPHRRFLEDLAKIADIRNYIIXX 1194
             S     P               P+  ++H +R  +PGPHRRFL  L+ +A+IR Y+   
Sbjct: 294  PSPPGQAP--------------PPKHNFIHEMRNYMPGPHRRFLAHLSTVANIRPYV--- 336

Query: 1195 XXXXXXXXXXXXXXXXXXCLLRETDEADDLIKAYNECLNQMKDFR 1329
                                 + +    ++ +AY+ CL  ++ FR
Sbjct: 337  --------------------QQHSQSHPEVAQAYDACLAMLRSFR 361


>gb|PIA19309.1| Indoleamine 2,3-dioxygenase [Coemansia reversa NRRL 1564]
          Length = 546

 Score =  328 bits (840), Expect = e-103
 Identities = 179/418 (42%), Positives = 249/418 (59%), Gaps = 18/418 (4%)
 Frame = +1

Query: 130  RLEDYDISPSTGFLPSIPPLQCLPDSYYEPWETLISMFHNLMLAGRLREYVKRLPILKTD 309
            RLEDYDISP+ GFLPS PPL+ LPD YY PWE ++  F+  +LA ++R  V+++P+L T 
Sbjct: 7    RLEDYDISPTHGFLPSEPPLRRLPDPYYTPWEHIMDRFNQFVLAHQIRRLVRKMPVLNTS 66

Query: 310  RLKTPEEYRRAFLVLSFIAHGYVWGK----YETVSDRLPANIAIPWVEVSKYLDVAPIIN 477
            RL T  EY+RAF +LSF+AH Y+WG+     E  S+ LPA+I+IPWVE++ +L + P++ 
Sbjct: 67   RLSTQSEYQRAFSILSFMAHAYIWGRNGAVAEPASEFLPASISIPWVEIADFLQLNPVVC 126

Query: 478  HAAVVTWNWSLL--FSDEPFKLNNLATLITFSNTLDESWFYLVTTAIEGFGGRALTSIMA 651
             AAV  WNW +L   +++P  + NL T+ TFS + DESWFYLVTTAIE    R L +I+A
Sbjct: 127  CAAVCHWNWQILDENAEDPMDICNLGTIQTFSGSTDESWFYLVTTAIEAKCARGLNAIIA 186

Query: 652  AIQATYDGXXXXXXXXXXXXSSTIFDINKTLQKMFKKCDPYVFYWKVRPYLSGWEN--ED 825
            A++A                + ++ D N  L++M+++CDPYVFYWK+R +L+GWEN  E 
Sbjct: 187  AVEAVEQDNIENVTLSLQQMAISLIDANFILERMYERCDPYVFYWKIRAFLAGWENMAEA 246

Query: 826  RLPKGLIYDGVDGND----ENGNPI---YRRYIGGSAGQSALIQALDIALSVKHYPTGIK 984
             LP G++Y+GVD  D    +N   +   +R+Y GGSA Q+ L+QA DIAL +KHYPTG K
Sbjct: 247  GLPYGVLYEGVDDTDTFSLDNWQSLIRRFRKYAGGSAAQTPLLQAFDIALGIKHYPTGQK 306

Query: 985  PHTNSSCPRYTSCSNGYPQPHDIHQYVSNGHTEP--QQPYLHRIRQNIPGPHRRFLEDLA 1158
                S         N              G +EP     YL ++R  +PG HRRFLEDLA
Sbjct: 307  GQQTSVVDARDRLRN-------------RGVSEPPVANSYLVQMRNYMPGGHRRFLEDLA 353

Query: 1159 KIADIRNYIIXXXXXXXXXXXXXXXXXXXXCLLRETDEADDLI-KAYNECLNQMKDFR 1329
                +R Y++                     LL  TD    L+ +AYN+C++ MK FR
Sbjct: 354  GTCRVREYVL-------------LTCPDSLLLLGSTDNPRVLLRRAYNDCVDLMKSFR 398