BLASTX 2.2.26 [Sep-21-2011]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= Ophiopogon25_contig00043494
         (1932 letters)

Database: All non-redundant GenBank CDS
translations+PDB+SwissProt+PIR+PRF excluding environmental samples
from WGS projects 
           149,584,005 sequences; 54,822,741,787 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gb|POG69495.1| neutral ceramidase-like protein [Rhizophagus irre...  1236   0.0  
gb|PKY43755.1| neutral ceramidase-like protein [Rhizophagus irre...  1236   0.0  
dbj|GBC14434.1| Neutral/alkaline nonlysosomal ceramidase [Rhizop...  1236   0.0  
gb|PKC57179.1| neutral ceramidase-like protein [Rhizophagus irre...  1232   0.0  
gb|ORX82000.1| Neutral/alkaline nonlysosomal ceramidase [Basidio...   628   0.0  
gb|ORX89074.1| Neutral/alkaline nonlysosomal ceramidase [Basidio...   618   0.0  
ref|XP_011454842.1| PREDICTED: neutral ceramidase [Crassostrea g...   571   0.0  
ref|XP_022319136.1| neutral ceramidase-like [Crassostrea virginica]   570   0.0  
ref|XP_019620213.1| PREDICTED: neutral ceramidase-like isoform X...   567   0.0  
ref|XP_022319861.1| neutral ceramidase-like [Crassostrea virginica]   565   0.0  
ref|XP_014680017.1| PREDICTED: neutral ceramidase-like [Priapulu...   562   0.0  
ref|XP_013094635.1| PREDICTED: neutral ceramidase-like isoform X...   557   0.0  
ref|XP_013094566.1| PREDICTED: neutral ceramidase-like isoform X...   557   0.0  
ref|XP_013402701.1| neutral ceramidase isoform X2 [Lingula anatina]   554   0.0  
ref|XP_023932283.1| neutral ceramidase isoform X1 [Lingula anatina]   554   0.0  
ref|XP_013402699.1| neutral ceramidase [Lingula anatina]              555   0.0  
gb|KVI11923.1| Neutral/alkaline nonlysosomal ceramidase [Cynara ...   547   0.0  
ref|XP_005100690.1| PREDICTED: neutral ceramidase-like [Aplysia ...   544   0.0  
ref|XP_002989773.1| hypothetical protein SELMODRAFT_130277 [Sela...   541   0.0  
ref|XP_002964917.1| hypothetical protein SELMODRAFT_167350 [Sela...   540   0.0  

>gb|POG69495.1| neutral ceramidase-like protein [Rhizophagus irregularis DAOM
            181602=DAOM 197198]
          Length = 699

 Score = 1236 bits (3198), Expect = 0.0
 Identities = 604/615 (98%), Positives = 608/615 (98%)
 Frame = -3

Query: 1930 KRVVFVSADLAMGSLAVRRATLEKLKESFGDLYNDENVAISGTHTHAGPAGYLQYALYQI 1751
            KRVVFVSADLAMGSLAVRRATLEKLKESFGDLYNDENVAISGTHTHAGPAGYLQYALYQI
Sbjct: 81   KRVVFVSADLAMGSLAVRRATLEKLKESFGDLYNDENVAISGTHTHAGPAGYLQYALYQI 140

Query: 1750 TSFGYFKENTEAISTGIYNSIVKAHNSIQPASIFVSTGELLNTNINRSPFSYEQNPEEER 1571
            TSFGYFKENTEAISTGIYNSIVKAHNSIQPASIFVSTGELLNTNINRSPFSYEQNPEEER
Sbjct: 141  TSFGYFKENTEAISTGIYNSIVKAHNSIQPASIFVSTGELLNTNINRSPFSYEQNPEEER 200

Query: 1570 SQYKYNVDKEMILLKFTNEKGDVIGSINWFPVHPVSMMNNNTLVSGDNKGTASYFLEREY 1391
            SQYKYNVDKEMILLKFTN KGDVIGSINWFPVHPVSMMNNNTLVSGDNKGTASYFLEREY
Sbjct: 201  SQYKYNVDKEMILLKFTNAKGDVIGSINWFPVHPVSMMNNNTLVSGDNKGTASYFLEREY 260

Query: 1390 NNGTLPGEETIIHAFANSNLGDSSPNIFGPYCADTGLPCEYRTSTCNGKKETCFGRGYGY 1211
            NN TLPGEETIIHAFANSNLGDSSPNIFGPYCADTGLPCEYRTSTCNGKKETCFGRGYGY
Sbjct: 261  NNSTLPGEETIIHAFANSNLGDSSPNIFGPYCADTGLPCEYRTSTCNGKKETCFGRGYGY 320

Query: 1210 LTGDDIYATRKIAELHVTKAKELIDTAKTPITGSIDYKFTKVDIQNYNFTLNGKTVSLCK 1031
            LTGDDIYATRKIAELHV KAKELIDTAKTPITGSIDYKFTKV+IQNYNFTLNGKTVSLCK
Sbjct: 321  LTGDDIYATRKIAELHVAKAKELIDTAKTPITGSIDYKFTKVNIQNYNFTLNGKTVSLCK 380

Query: 1030 AALGYSMIAGTTDGPGGFNFIQGDNSTGNPFWKLITRIIKQPTKETIECQRPKPIVLATG 851
            AALGYSMIAGTTDGPGGFNFIQGDNSTGNPFWKLITRIIKQPTKETIECQRPKPIVLATG
Sbjct: 381  AALGYSMIAGTTDGPGGFNFIQGDNSTGNPFWKLITRIIKQPTKETIECQRPKPIVLATG 440

Query: 850  EMRSPYDFTPSIIEIQLLKIGNFIICVVPGEFTTMSGRRLTKTVKNILMKKGVIDENGIV 671
            EMRSPYDFTPSIIEIQLLKIGNFIICVVPGEFTTMSGRRLTKTVKNILMKKGVIDENGIV
Sbjct: 441  EMRSPYDFTPSIIEIQLLKIGNFIICVVPGEFTTMSGRRLTKTVKNILMKKGVIDENGIV 500

Query: 670  VVSGPSNSYTHYITTPEEYLVQRYEGGSTIYGPNTLNAYLQLYTDLSIALADNLYVPIGP 491
            +VSGPSNSYTHYITTPEEYLVQRYEGGSTIYGPNTLNAYLQLYTDLSIALADNLYVPIGP
Sbjct: 501  IVSGPSNSYTHYITTPEEYLVQRYEGGSTIYGPNTLNAYLQLYTDLSIALADNLYVPIGP 560

Query: 490  EAPDFTDKALNFVLPVIVDIPPLFKKFGDVTKDANKKYIRGETVEVEFVGGHPKNRIQLE 311
            EAPDFTDKALNFVLPVIVDIPPLFKKFGDVTKDANKKYIRGETV VEFVGGHPKN IQLE
Sbjct: 561  EAPDFTDKALNFVLPVIVDIPPLFKKFGDVTKDANKKYIRGETVAVEFVGGHPKNHIQLE 620

Query: 310  GSFLYVQRLENNNNWINFKNDGDITTQFKWLGNSIVRITWEIGDDVEAGTYRIFYQGHHK 131
            GSFLYVQRLENNNNW+NFKNDGDITT+FKWLGNSIVRITWEI DDVEAGTYRIFYQGHHK
Sbjct: 621  GSFLYVQRLENNNNWVNFKNDGDITTKFKWLGNSIVRITWEIDDDVEAGTYRIFYQGHHK 680

Query: 130  QLGGKIVPEFGTTSN 86
            QLGGKIVPEFG TSN
Sbjct: 681  QLGGKIVPEFGITSN 695


>gb|PKY43755.1| neutral ceramidase-like protein [Rhizophagus irregularis]
          Length = 686

 Score = 1236 bits (3198), Expect = 0.0
 Identities = 604/615 (98%), Positives = 608/615 (98%)
 Frame = -3

Query: 1930 KRVVFVSADLAMGSLAVRRATLEKLKESFGDLYNDENVAISGTHTHAGPAGYLQYALYQI 1751
            KRVVFVSADLAMGSLAVRRATLEKLKESFGDLYNDENVAISGTHTHAGPAGYLQYALYQI
Sbjct: 68   KRVVFVSADLAMGSLAVRRATLEKLKESFGDLYNDENVAISGTHTHAGPAGYLQYALYQI 127

Query: 1750 TSFGYFKENTEAISTGIYNSIVKAHNSIQPASIFVSTGELLNTNINRSPFSYEQNPEEER 1571
            TSFGYFKENTEAISTGIYNSIVKAHNSIQPASIFVSTGELLNTNINRSPFSYEQNPEEER
Sbjct: 128  TSFGYFKENTEAISTGIYNSIVKAHNSIQPASIFVSTGELLNTNINRSPFSYEQNPEEER 187

Query: 1570 SQYKYNVDKEMILLKFTNEKGDVIGSINWFPVHPVSMMNNNTLVSGDNKGTASYFLEREY 1391
            SQYKYNVDKEMILLKFTN KGDVIGSINWFPVHPVSMMNNNTLVSGDNKGTASYFLEREY
Sbjct: 188  SQYKYNVDKEMILLKFTNAKGDVIGSINWFPVHPVSMMNNNTLVSGDNKGTASYFLEREY 247

Query: 1390 NNGTLPGEETIIHAFANSNLGDSSPNIFGPYCADTGLPCEYRTSTCNGKKETCFGRGYGY 1211
            NN TLPGEETIIHAFANSNLGDSSPNIFGPYCADTGLPCEYRTSTCNGKKETCFGRGYGY
Sbjct: 248  NNSTLPGEETIIHAFANSNLGDSSPNIFGPYCADTGLPCEYRTSTCNGKKETCFGRGYGY 307

Query: 1210 LTGDDIYATRKIAELHVTKAKELIDTAKTPITGSIDYKFTKVDIQNYNFTLNGKTVSLCK 1031
            LTGDDIYATRKIAELHV KAKELIDTAKTPITGSIDYKFTKV+IQNYNFTLNGKTVSLCK
Sbjct: 308  LTGDDIYATRKIAELHVAKAKELIDTAKTPITGSIDYKFTKVNIQNYNFTLNGKTVSLCK 367

Query: 1030 AALGYSMIAGTTDGPGGFNFIQGDNSTGNPFWKLITRIIKQPTKETIECQRPKPIVLATG 851
            AALGYSMIAGTTDGPGGFNFIQGDNSTGNPFWKLITRIIKQPTKETIECQRPKPIVLATG
Sbjct: 368  AALGYSMIAGTTDGPGGFNFIQGDNSTGNPFWKLITRIIKQPTKETIECQRPKPIVLATG 427

Query: 850  EMRSPYDFTPSIIEIQLLKIGNFIICVVPGEFTTMSGRRLTKTVKNILMKKGVIDENGIV 671
            EMRSPYDFTPSIIEIQLLKIGNFIICVVPGEFTTMSGRRLTKTVKNILMKKGVIDENGIV
Sbjct: 428  EMRSPYDFTPSIIEIQLLKIGNFIICVVPGEFTTMSGRRLTKTVKNILMKKGVIDENGIV 487

Query: 670  VVSGPSNSYTHYITTPEEYLVQRYEGGSTIYGPNTLNAYLQLYTDLSIALADNLYVPIGP 491
            +VSGPSNSYTHYITTPEEYLVQRYEGGSTIYGPNTLNAYLQLYTDLSIALADNLYVPIGP
Sbjct: 488  IVSGPSNSYTHYITTPEEYLVQRYEGGSTIYGPNTLNAYLQLYTDLSIALADNLYVPIGP 547

Query: 490  EAPDFTDKALNFVLPVIVDIPPLFKKFGDVTKDANKKYIRGETVEVEFVGGHPKNRIQLE 311
            EAPDFTDKALNFVLPVIVDIPPLFKKFGDVTKDANKKYIRGETV VEFVGGHPKN IQLE
Sbjct: 548  EAPDFTDKALNFVLPVIVDIPPLFKKFGDVTKDANKKYIRGETVTVEFVGGHPKNHIQLE 607

Query: 310  GSFLYVQRLENNNNWINFKNDGDITTQFKWLGNSIVRITWEIGDDVEAGTYRIFYQGHHK 131
            GSFLYVQRLENNNNW+NFKNDGDITT+FKWLGNSIVRITWEI DDVEAGTYRIFYQGHHK
Sbjct: 608  GSFLYVQRLENNNNWVNFKNDGDITTKFKWLGNSIVRITWEIDDDVEAGTYRIFYQGHHK 667

Query: 130  QLGGKIVPEFGTTSN 86
            QLGGKIVPEFG TSN
Sbjct: 668  QLGGKIVPEFGITSN 682


>dbj|GBC14434.1| Neutral/alkaline nonlysosomal ceramidase [Rhizophagus irregularis
            DAOM 181602]
 gb|PKC06905.1| neutral ceramidase-like protein [Rhizophagus irregularis]
 gb|PKK68696.1| neutral ceramidase-like protein [Rhizophagus irregularis]
 gb|PKY31427.1| neutral ceramidase-like protein [Rhizophagus irregularis]
          Length = 686

 Score = 1236 bits (3198), Expect = 0.0
 Identities = 604/615 (98%), Positives = 608/615 (98%)
 Frame = -3

Query: 1930 KRVVFVSADLAMGSLAVRRATLEKLKESFGDLYNDENVAISGTHTHAGPAGYLQYALYQI 1751
            KRVVFVSADLAMGSLAVRRATLEKLKESFGDLYNDENVAISGTHTHAGPAGYLQYALYQI
Sbjct: 68   KRVVFVSADLAMGSLAVRRATLEKLKESFGDLYNDENVAISGTHTHAGPAGYLQYALYQI 127

Query: 1750 TSFGYFKENTEAISTGIYNSIVKAHNSIQPASIFVSTGELLNTNINRSPFSYEQNPEEER 1571
            TSFGYFKENTEAISTGIYNSIVKAHNSIQPASIFVSTGELLNTNINRSPFSYEQNPEEER
Sbjct: 128  TSFGYFKENTEAISTGIYNSIVKAHNSIQPASIFVSTGELLNTNINRSPFSYEQNPEEER 187

Query: 1570 SQYKYNVDKEMILLKFTNEKGDVIGSINWFPVHPVSMMNNNTLVSGDNKGTASYFLEREY 1391
            SQYKYNVDKEMILLKFTN KGDVIGSINWFPVHPVSMMNNNTLVSGDNKGTASYFLEREY
Sbjct: 188  SQYKYNVDKEMILLKFTNAKGDVIGSINWFPVHPVSMMNNNTLVSGDNKGTASYFLEREY 247

Query: 1390 NNGTLPGEETIIHAFANSNLGDSSPNIFGPYCADTGLPCEYRTSTCNGKKETCFGRGYGY 1211
            NN TLPGEETIIHAFANSNLGDSSPNIFGPYCADTGLPCEYRTSTCNGKKETCFGRGYGY
Sbjct: 248  NNSTLPGEETIIHAFANSNLGDSSPNIFGPYCADTGLPCEYRTSTCNGKKETCFGRGYGY 307

Query: 1210 LTGDDIYATRKIAELHVTKAKELIDTAKTPITGSIDYKFTKVDIQNYNFTLNGKTVSLCK 1031
            LTGDDIYATRKIAELHV KAKELIDTAKTPITGSIDYKFTKV+IQNYNFTLNGKTVSLCK
Sbjct: 308  LTGDDIYATRKIAELHVAKAKELIDTAKTPITGSIDYKFTKVNIQNYNFTLNGKTVSLCK 367

Query: 1030 AALGYSMIAGTTDGPGGFNFIQGDNSTGNPFWKLITRIIKQPTKETIECQRPKPIVLATG 851
            AALGYSMIAGTTDGPGGFNFIQGDNSTGNPFWKLITRIIKQPTKETIECQRPKPIVLATG
Sbjct: 368  AALGYSMIAGTTDGPGGFNFIQGDNSTGNPFWKLITRIIKQPTKETIECQRPKPIVLATG 427

Query: 850  EMRSPYDFTPSIIEIQLLKIGNFIICVVPGEFTTMSGRRLTKTVKNILMKKGVIDENGIV 671
            EMRSPYDFTPSIIEIQLLKIGNFIICVVPGEFTTMSGRRLTKTVKNILMKKGVIDENGIV
Sbjct: 428  EMRSPYDFTPSIIEIQLLKIGNFIICVVPGEFTTMSGRRLTKTVKNILMKKGVIDENGIV 487

Query: 670  VVSGPSNSYTHYITTPEEYLVQRYEGGSTIYGPNTLNAYLQLYTDLSIALADNLYVPIGP 491
            +VSGPSNSYTHYITTPEEYLVQRYEGGSTIYGPNTLNAYLQLYTDLSIALADNLYVPIGP
Sbjct: 488  IVSGPSNSYTHYITTPEEYLVQRYEGGSTIYGPNTLNAYLQLYTDLSIALADNLYVPIGP 547

Query: 490  EAPDFTDKALNFVLPVIVDIPPLFKKFGDVTKDANKKYIRGETVEVEFVGGHPKNRIQLE 311
            EAPDFTDKALNFVLPVIVDIPPLFKKFGDVTKDANKKYIRGETV VEFVGGHPKN IQLE
Sbjct: 548  EAPDFTDKALNFVLPVIVDIPPLFKKFGDVTKDANKKYIRGETVAVEFVGGHPKNHIQLE 607

Query: 310  GSFLYVQRLENNNNWINFKNDGDITTQFKWLGNSIVRITWEIGDDVEAGTYRIFYQGHHK 131
            GSFLYVQRLENNNNW+NFKNDGDITT+FKWLGNSIVRITWEI DDVEAGTYRIFYQGHHK
Sbjct: 608  GSFLYVQRLENNNNWVNFKNDGDITTKFKWLGNSIVRITWEIDDDVEAGTYRIFYQGHHK 667

Query: 130  QLGGKIVPEFGTTSN 86
            QLGGKIVPEFG TSN
Sbjct: 668  QLGGKIVPEFGITSN 682


>gb|PKC57179.1| neutral ceramidase-like protein [Rhizophagus irregularis]
          Length = 686

 Score = 1232 bits (3188), Expect = 0.0
 Identities = 603/615 (98%), Positives = 607/615 (98%)
 Frame = -3

Query: 1930 KRVVFVSADLAMGSLAVRRATLEKLKESFGDLYNDENVAISGTHTHAGPAGYLQYALYQI 1751
            KRVVFVSADLAMGSLAVRRATLEKLKESFGDLYNDENVAISGTHTHAGPAGYLQYALYQI
Sbjct: 68   KRVVFVSADLAMGSLAVRRATLEKLKESFGDLYNDENVAISGTHTHAGPAGYLQYALYQI 127

Query: 1750 TSFGYFKENTEAISTGIYNSIVKAHNSIQPASIFVSTGELLNTNINRSPFSYEQNPEEER 1571
            TSFGYFKENTEAISTGIYNSIVKAHNSIQPASIFVSTGELLNTNINRSPFSYEQNPEEER
Sbjct: 128  TSFGYFKENTEAISTGIYNSIVKAHNSIQPASIFVSTGELLNTNINRSPFSYEQNPEEER 187

Query: 1570 SQYKYNVDKEMILLKFTNEKGDVIGSINWFPVHPVSMMNNNTLVSGDNKGTASYFLEREY 1391
            SQYKYNVDKEMILLKFTN KGDVIGSINWFPVHPVSMMNNNTLVSGDNKGTASYFLEREY
Sbjct: 188  SQYKYNVDKEMILLKFTNAKGDVIGSINWFPVHPVSMMNNNTLVSGDNKGTASYFLEREY 247

Query: 1390 NNGTLPGEETIIHAFANSNLGDSSPNIFGPYCADTGLPCEYRTSTCNGKKETCFGRGYGY 1211
            NN TLPGEETIIHAFANSNLGDSSPNIFGPYCADTGLPCEYRTSTCNGKKETCFGRGYGY
Sbjct: 248  NNSTLPGEETIIHAFANSNLGDSSPNIFGPYCADTGLPCEYRTSTCNGKKETCFGRGYGY 307

Query: 1210 LTGDDIYATRKIAELHVTKAKELIDTAKTPITGSIDYKFTKVDIQNYNFTLNGKTVSLCK 1031
            LTGDDIYATRKIAELHV KAKELIDTAKTPITGSIDYKFTKV+IQNYNFTLNGKTVSLCK
Sbjct: 308  LTGDDIYATRKIAELHVAKAKELIDTAKTPITGSIDYKFTKVNIQNYNFTLNGKTVSLCK 367

Query: 1030 AALGYSMIAGTTDGPGGFNFIQGDNSTGNPFWKLITRIIKQPTKETIECQRPKPIVLATG 851
            AALGYSMIAGTTDGPGGFNFIQGDNSTGNPFWKLITRIIKQPTKETIE QRPKPIVLATG
Sbjct: 368  AALGYSMIAGTTDGPGGFNFIQGDNSTGNPFWKLITRIIKQPTKETIELQRPKPIVLATG 427

Query: 850  EMRSPYDFTPSIIEIQLLKIGNFIICVVPGEFTTMSGRRLTKTVKNILMKKGVIDENGIV 671
            EMRSPYDFTPSIIEIQLLKIGNFIICVVPGEFTTMSGRRLTKTVKNILMKKGVIDENGIV
Sbjct: 428  EMRSPYDFTPSIIEIQLLKIGNFIICVVPGEFTTMSGRRLTKTVKNILMKKGVIDENGIV 487

Query: 670  VVSGPSNSYTHYITTPEEYLVQRYEGGSTIYGPNTLNAYLQLYTDLSIALADNLYVPIGP 491
            +VSGPSNSYTHYITTPEEYLVQRYEGGSTIYGPNTLNAYLQLYTDLSIALADNLYVPIGP
Sbjct: 488  IVSGPSNSYTHYITTPEEYLVQRYEGGSTIYGPNTLNAYLQLYTDLSIALADNLYVPIGP 547

Query: 490  EAPDFTDKALNFVLPVIVDIPPLFKKFGDVTKDANKKYIRGETVEVEFVGGHPKNRIQLE 311
            EAPDFTDKALNFVLPVIVDIPPLFKKFGDVTKDANKKYIRGETV VEFVGGHPKN IQLE
Sbjct: 548  EAPDFTDKALNFVLPVIVDIPPLFKKFGDVTKDANKKYIRGETVAVEFVGGHPKNHIQLE 607

Query: 310  GSFLYVQRLENNNNWINFKNDGDITTQFKWLGNSIVRITWEIGDDVEAGTYRIFYQGHHK 131
            GSFLYVQRLENNNNW+NFKNDGDITT+FKWLGNSIVRITWEI DDVEAGTYRIFYQGHHK
Sbjct: 608  GSFLYVQRLENNNNWVNFKNDGDITTKFKWLGNSIVRITWEIDDDVEAGTYRIFYQGHHK 667

Query: 130  QLGGKIVPEFGTTSN 86
            QLGGKIVPEFG TSN
Sbjct: 668  QLGGKIVPEFGITSN 682


>gb|ORX82000.1| Neutral/alkaline nonlysosomal ceramidase [Basidiobolus meristosporus
            CBS 931.73]
          Length = 692

 Score =  628 bits (1619), Expect = 0.0
 Identities = 316/618 (51%), Positives = 420/618 (67%), Gaps = 5/618 (0%)
 Frame = -3

Query: 1930 KRVVFVSADLAMGSLAVRRATLEKLKESFGDLYNDENVAISGTHTHAGPAGYLQYALYQI 1751
            KRVV+VSAD+ M S  +RR  + KLK  +G+LYND+NVA++GTHTH+GP G+ QY LYQ 
Sbjct: 75   KRVVYVSADIGMISQVIRRRVVAKLKTLYGNLYNDDNVALTGTHTHSGPGGWHQYVLYQF 134

Query: 1750 TSFGYFKENTEAISTGIYNSIVKAHNSIQPASIFVSTGELLNTNINRSPFSYEQNPEEER 1571
            T+ G+ +E T  +  GI NSI KAH S+ P SI  S+G++ N NINRSP++YEQNPE ER
Sbjct: 135  TNLGFIEEATRPVVDGIVNSIKKAHESMVPGSITTSSGDVENGNINRSPWAYEQNPESER 194

Query: 1570 SQYKYNVDKEMILLKFTNEKGDVIGSINWFPVHPVSMMNNNTLVSGDNKGTASYFLEREY 1391
            ++YK+N D  M L+KFT+E G  IG +NW+ VH  SM ++N L+SGDNKG ASY  E+E 
Sbjct: 195  ARYKHNTDTNMRLIKFTDESGKPIGILNWYAVHCTSMNSDNLLISGDNKGYASYLFEKEM 254

Query: 1390 NNGTLPGEETIIHAFANSNLGDSSPNIFGPYCADTGLPCEYRTSTCNGKKETCFGRGYGY 1211
            N  TLPG    +  FA SN+GD SPN  GP C DTGLPC+Y+TSTC+GK       G GY
Sbjct: 255  NENTLPGTGKFVAGFAQSNMGDVSPNTQGPRCLDTGLPCDYKTSTCDGKN----ALGPGY 310

Query: 1210 LTGDDIYATRKIAELHVTKAKELIDTAKTPITGSIDYKFTKVDIQNYNFTLNG-KTVSLC 1034
             TG D+ +TR I       A++L++ A   I GSID++   VD+      LN   TV+LC
Sbjct: 311  ETGGDVESTRIIGSYQYQTARKLMNEATNAIKGSIDFRHQFVDMTGVQVKLNATTTVNLC 370

Query: 1033 KAALGYSMIAGTTDGPGGFNFIQGDNSTGNPFWKLITRIIKQPTKETIECQRPKPIVLAT 854
            K A+GYS  AGTTDGPG F+F QGD+   +PFW ++   I  P+KE   C  PKPI+LAT
Sbjct: 371  KPAMGYSFAAGTTDGPGEFDFKQGDSDKKHPFWDVVRAFITTPSKELEACHSPKPILLAT 430

Query: 853  GEMRSPYDFTPSIIEIQLLKIGNFIICVVPGEFTTMSGRRLTKTVKNILMKKGVIDENGI 674
            GE++ PY + P +++IQ+L+IG  +I VVPGEFTTMSGRRL + +  + ++   I ++ I
Sbjct: 431  GEIKLPYMWQPKVVDIQILRIGQLVIAVVPGEFTTMSGRRLREAIAKVFLETSDI-KDPI 489

Query: 673  VVVSGPSNSYTHYITTPEEYLVQRYEGGSTIYGPNTLNAYLQLYTDLSIALADNLYVPIG 494
            VV++GPSN+Y+ YI TPEEY VQRYEGGSTIYGPNTL  Y+QLY++++ A+  N      
Sbjct: 490  VVLAGPSNTYSSYIATPEEYSVQRYEGGSTIYGPNTLPGYIQLYSEMAAAMIQNKPTVSL 549

Query: 493  PEAPDFTDKALNFVLPVIVDIPPLFKKFGDVTKDANKKYIRGETVEVEFVGGHPKNRIQL 314
             + PD T  A+N    V++D  P+ KKFG+V KDAN  Y  G TV V FVGGHPKN+I L
Sbjct: 550  TQPPDLTPGAINLQTGVVLDTAPIGKKFGNVLKDANDSYKPGNTVSVTFVGGHPKNKITL 609

Query: 313  EGSFLYVQRLENNNNWINFKNDGDITTQFKW----LGNSIVRITWEIGDDVEAGTYRIFY 146
            E +FL V+ +++++ W   KNDGD +T+F+W    +  S+V I W+I  D + G+YRI Y
Sbjct: 610  EDTFLTVE-MQSSDGWKTVKNDGDWSTKFQWARQGVSESLVTIEWQIEPDTKPGSYRIGY 668

Query: 145  QGHHKQLGGKIVPEFGTT 92
             G +K   GKI P  G T
Sbjct: 669  FGANKAF-GKITPHSGYT 685


>gb|ORX89074.1| Neutral/alkaline nonlysosomal ceramidase [Basidiobolus meristosporus
            CBS 931.73]
          Length = 693

 Score =  618 bits (1593), Expect = 0.0
 Identities = 306/619 (49%), Positives = 417/619 (67%), Gaps = 6/619 (0%)
 Frame = -3

Query: 1927 RVVFVSADLAMGSLAVRRATLEKLKESFGDLYNDENVAISGTHTHAGPAGYLQYALYQIT 1748
            R+ +VSADL M S  VRR  +E LK+ +GDLYND NVA++GTHTH+GP G+ QY LYQ T
Sbjct: 72   RIAYVSADLGMISQVVRRRVIEALKQLYGDLYNDNNVALTGTHTHSGPGGWHQYVLYQFT 131

Query: 1747 SFGYFKENTEAISTGIYNSIVKAHNSIQPASIFVSTGELLNTNINRSPFSYEQNPEEERS 1568
            + G+ ++ T  +  GI NSI +AH ++ P  I  S G++ N NINRSP++Y+QNP+ ER+
Sbjct: 132  NLGFIEDATRPVVNGIVNSIQRAHENMTPGFITTSAGDVENGNINRSPWAYDQNPQSERA 191

Query: 1567 QYKYNVDKEMILLKFTNEKGDVIGSINWFPVHPVSMMNNNTLVSGDNKGTASYFLEREYN 1388
            +YK+N D+EM L+KFTNE G+ +G +NW+ VH  SM N N L+SGDNKG A+Y  ERE N
Sbjct: 192  RYKHNTDQEMRLVKFTNEAGEPLGILNWYAVHCTSMNNENLLISGDNKGYAAYAFEREMN 251

Query: 1387 -NGTLPGEETIIHAFANSNLGDSSPNIFGPYCADTGLPCEYRTSTCNGKKETCFGRGYGY 1211
             +  LPG    +  FA SN+GD SPN  GP C D+GLPC+Y+TSTCNGK E C  RG GY
Sbjct: 252  GDDILPGTGKFVAGFAQSNMGDVSPNTQGPRCLDSGLPCDYKTSTCNGKNELCVARGPGY 311

Query: 1210 LTGDDIYATRKIAELHVTKAKELIDTAKTPITGSIDYKFTKVDIQNYNFTL-NGKTVSLC 1034
             TG D+ +TR I       AK L++ AK  + G +D++   VD+      L N  T  LC
Sbjct: 312  ETGGDVESTRIIGSYQYETAKRLMNEAKEYVKGPVDFRHQFVDLTKVEVKLGNSTTKRLC 371

Query: 1033 KAALGYSMIAGTTDGPGGFNFIQGDNSTGNPFWKLITRIIKQPTKETIECQRPKPIVLAT 854
            K A+GYS  AGTTDGPG F+F QGD++  +PFW ++   I +P++E  ECQ PKP++LAT
Sbjct: 372  KPAMGYSFAAGTTDGPGEFDFTQGDSNVSHPFWDVVRAFITKPSEELKECQSPKPVLLAT 431

Query: 853  GEMRSPYDFTPSIIEIQLLKIGNFIICVVPGEFTTMSGRRLTKTVKNILMKKGVIDENGI 674
            GE++ PY + P +++IQ+L++G  +I VVPGEFTTMSGRRL + +  +  +   + +N I
Sbjct: 432  GEIKLPYMWQPRVVDIQILRVGQLVIAVVPGEFTTMSGRRLREAIGQVFAETSDL-KNPI 490

Query: 673  VVVSGPSNSYTHYITTPEEYLVQRYEGGSTIYGPNTLNAYLQLYTDLSIALADNLYVPIG 494
            VV++GPSN+Y+ Y+TTPEEY  QRYEG STIYGPNTL+ Y+QLY +++ A+     V   
Sbjct: 491  VVLAGPSNTYSSYVTTPEEYSAQRYEGASTIYGPNTLDGYIQLYKEVAAAMIQGKPVVSL 550

Query: 493  PEAPDFTDKALNFVLPVIVDIPPLFKKFGDVTKDANKKYIRGETVEVEFVGGHPKNRIQL 314
               PD T  A+N    V++D  P+ KKFGDV KDA   Y  G+TV V FVGGHPKN++ L
Sbjct: 551  ISTPDLTRNAINLQTGVVLDTAPIGKKFGDVLKDAQATYKIGDTVSVAFVGGHPKNKVAL 610

Query: 313  EGSFLYVQRLENNNNWINFKNDGDITTQFKW----LGNSIVRITWEIGDDVEAGTYRIFY 146
            E +FL V+ ++ +++W   +NDGD  T+F+W    +  S V I W+I  +V+ G YRI Y
Sbjct: 611  EETFLTVE-MQTSDDWKVVRNDGDWCTKFQWKRQGIAESNVTIQWQIEPNVKPGIYRIGY 669

Query: 145  QGHHKQLGGKIVPEFGTTS 89
             G +K   GKI    G +S
Sbjct: 670  FGANKAF-GKISSHSGYSS 687


>ref|XP_011454842.1| PREDICTED: neutral ceramidase [Crassostrea gigas]
 gb|EKC40757.1| Neutral ceramidase B [Crassostrea gigas]
          Length = 740

 Score =  571 bits (1472), Expect = 0.0
 Identities = 296/614 (48%), Positives = 392/614 (63%), Gaps = 9/614 (1%)
 Frame = -3

Query: 1927 RVVFVSADLAMGSLAVRRATLEKLKESFGDLYNDENVAISGTHTHAGPAGYLQYALYQIT 1748
            R+VFVS D  M S  ++   +++LK  +GDLYN+ NVAISGTHTH+GP G+ QY LY IT
Sbjct: 77   RIVFVSTDSCMQSQGLKLEIIKRLKSKYGDLYNERNVAISGTHTHSGPGGFHQYLLYDIT 136

Query: 1747 SFGYFKENTEAISTGIYNSIVKAHNSIQPASIFVSTGELLNTNINRSPFSYEQNPEEERS 1568
            S G+  E    +  GI  SI KAHNS++P +++V+TGELL +NINRSP +Y  NP EER+
Sbjct: 137  SLGFVNETFVPLVEGIVASIDKAHNSMKPGNLYVNTGELLESNINRSPTAYLNNPAEERA 196

Query: 1567 QYKYNVDKEMILLKFTNEKGDVIGSINWFPVHPVSMMNNNTLVSGDNKGTASYFLEREYN 1388
            +YKYNVDK M +L+ T+ + + IG INWF VH  SM N N L+S DNKG A+   E + N
Sbjct: 197  KYKYNVDKNMTVLRLTDAQNNGIGMINWFAVHCTSMNNTNHLISSDNKGLAAQMFEADMN 256

Query: 1387 NGTLPGEETIIHAFANSNLGDSSPNIFGPYCADTGLPCEYRTSTCNGKKETCFGRGYGYL 1208
             G  PG+   + AFA SN GD SPN  GP+C DTG PC+  TSTCNG+ E C   G    
Sbjct: 257  KGAFPGKGKFVAAFAQSNEGDVSPNTKGPHCMDTGKPCDVPTSTCNGRNELCVSPG---- 312

Query: 1207 TGDDIY-ATRKIAELHVTKAKELI-DTAKTPITGSIDYKFTKVDIQNYNFTLNGKT-VSL 1037
             G D+Y +TR IA+    KAK L  D +   + G +D++ T VD+ N    +N  T V  
Sbjct: 313  PGKDMYDSTRIIAKNQYQKAKILYNDPSNMKLEGPVDFRHTYVDMSNVMVQINQTTKVKT 372

Query: 1036 CKAALGYSMIAGTTDGPGGFNFIQGDNSTGNPFWKLITRIIKQPTKETIECQRPKPIVLA 857
            CK A+G+S  AGTTDGPG FNF QGD +T NPFW  +   +K+P+ E + CQ PKPI+L 
Sbjct: 373  CKPAMGFSFAAGTTDGPGAFNFTQGD-TTDNPFWDFVRDFLKKPSPEQLACQHPKPILLD 431

Query: 856  TGEMRSPYDFTPSIIEIQLLKIGNFIICVVPGEFTTMSGRRLTKTVKNILMKKGVIDENG 677
            TGEM  PY ++PSI+++Q+ +IG   I  VP EF+TMSGRR   ++   L   G    N 
Sbjct: 432  TGEMTVPYAWSPSIVDLQIFRIGQLAIISVPAEFSTMSGRRTRDSITATLKAAG-FPANT 490

Query: 676  IVVVSGPSNSYTHYITTPEEYLVQRYEGGSTIYGPNTLNAYLQLYTDLSIALADNLYVPI 497
            + V++G +N Y  Y+TT EEY +QRYEG STIYGP+TL A++Q +  L+ ALA     P 
Sbjct: 491  VSVIAGLTNDYADYVTTYEEYQIQRYEGASTIYGPHTLEAFIQEFNKLADALAKGTPAPK 550

Query: 496  GPEAPDFTDKALNFVLPVIVDIPPLFKKFGDVTKDANKKYIRGETVEVEFVGGHPKNRIQ 317
            GP  P+  DK L+F+ PV+ D  P  K FGDV  DA+ +Y +G +V+V F+G +P+N ++
Sbjct: 551  GPTPPNLLDKQLSFLPPVVFDHAPFGKSFGDVVVDADVQYKQGSSVKVTFIGANPRNNVK 610

Query: 316  LEGSFLYVQRLENNNNWINFKNDGDITTQFKW------LGNSIVRITWEIGDDVEAGTYR 155
            LEG+FL V+ L+ +NNW     D    T+F+W      LG S V ITW+I      GTYR
Sbjct: 611  LEGTFLSVEMLQPDNNWKVVFTDSQWETKFEWKHTSLLLGESEVTITWDIPQTQALGTYR 670

Query: 154  IFYQGHHKQLGGKI 113
            I Y G  K L  KI
Sbjct: 671  IQYFGDAKSLDQKI 684


>ref|XP_022319136.1| neutral ceramidase-like [Crassostrea virginica]
          Length = 740

 Score =  570 bits (1470), Expect = 0.0
 Identities = 297/621 (47%), Positives = 396/621 (63%), Gaps = 8/621 (1%)
 Frame = -3

Query: 1927 RVVFVSADLAMGSLAVRRATLEKLKESFGDLYNDENVAISGTHTHAGPAGYLQYALYQIT 1748
            R+VFVS D  M S  ++   +++L+  +GDLYN+ NVAISGTHTH+GP G+ QY LY +T
Sbjct: 77   RIVFVSTDSCMQSQGLKLEIIKRLRSKYGDLYNERNVAISGTHTHSGPGGFHQYLLYDVT 136

Query: 1747 SFGYFKENTEAISTGIYNSIVKAHNSIQPASIFVSTGELLNTNINRSPFSYEQNPEEERS 1568
            S G+  E   ++  GI  SI KAHNS++P +++V+TGELL++NINRSP +Y  NP EER+
Sbjct: 137  SLGFVNETFVSLVEGIVASIDKAHNSMKPGNLYVNTGELLDSNINRSPTAYLNNPAEERA 196

Query: 1567 QYKYNVDKEMILLKFTNEKGDVIGSINWFPVHPVSMMNNNTLVSGDNKGTASYFLEREYN 1388
            +YKY+VDK M +L+ T+ + + IG INWF VH  SM N N L+S DNKG A+   E + N
Sbjct: 197  KYKYDVDKNMTVLRMTDAQNNGIGMINWFAVHCTSMNNTNHLISSDNKGLAAQMFEADMN 256

Query: 1387 NGTLPGEETIIHAFANSNLGDSSPNIFGPYCADTGLPCEYRTSTCNGKKETCFGRGYGYL 1208
             G  PG+   + AFA SN GD SPN  GP+C DTG PC+  TSTCNG+ E C   G G  
Sbjct: 257  KGGFPGKGKFVAAFAQSNEGDVSPNTKGPHCMDTGKPCDVPTSTCNGRNELCVSPGPG-- 314

Query: 1207 TGDDIYATRKIAELHVTKAKELI-DTAKTPITGSIDYKFTKVDIQNYNFTLNGKT-VSLC 1034
              D   +TR IA     KAK L  D A   + G +D++ T VD+ +    +N  T V  C
Sbjct: 315  -KDMFDSTRIIASNQYKKAKILYSDPAGMKLEGPVDFRHTYVDMSSVMVQINQTTKVKTC 373

Query: 1033 KAALGYSMIAGTTDGPGGFNFIQGDNSTGNPFWKLITRIIKQPTKETIECQRPKPIVLAT 854
            K A+G+S  AGTTDGPG FNF QGD +T NPFW  I   +K+PT E + CQ PKPI+L T
Sbjct: 374  KPAMGFSFAAGTTDGPGAFNFTQGD-TTDNPFWDFIRDFLKKPTPEQLACQHPKPILLDT 432

Query: 853  GEMRSPYDFTPSIIEIQLLKIGNFIICVVPGEFTTMSGRRLTKTVKNILMKKGVIDENGI 674
            GEM +PY ++PSI+++Q+ +IG   I  VP EF+TMSGRR T+      +K G    N +
Sbjct: 433  GEMTAPYAWSPSIVDLQIFRIGQLAIISVPAEFSTMSGRR-TRDSITATLKAGGFPANTV 491

Query: 673  VVVSGPSNSYTHYITTPEEYLVQRYEGGSTIYGPNTLNAYLQLYTDLSIALADNLYVPIG 494
             V++G +N Y  Y+TT EEY VQRYEG STIYGP+TL A++Q +  L+ ALA     P G
Sbjct: 492  SVIAGLTNDYADYVTTYEEYQVQRYEGASTIYGPHTLQAFIQEFNKLADALAKGTPSPKG 551

Query: 493  PEAPDFTDKALNFVLPVIVDIPPLFKKFGDVTKDANKKYIRGETVEVEFVGGHPKNRIQL 314
            P  P+  DK L+F+ PV+ D  P   KFGDV  DAN +Y +G++V+V F+G +P+N ++L
Sbjct: 552  PTPPNLLDKQLSFLPPVVFDHAPFGSKFGDVVVDANSQYKQGDSVKVTFIGANPRNNVKL 611

Query: 313  EGSFLYVQRLENNNNWINFKNDGDITTQFKW------LGNSIVRITWEIGDDVEAGTYRI 152
            E +FL V+ L+ +NNW     D    T+F+W      LG S V ITW+I      GTYRI
Sbjct: 612  EDTFLSVEMLQPDNNWKVVFTDSQWETKFEWKHTSLLLGESEVTITWDIPQSQAPGTYRI 671

Query: 151  FYQGHHKQLGGKIVPEFGTTS 89
             Y G  K L  KI    G ++
Sbjct: 672  QYFGDAKSLDQKITSFTGKST 692


>ref|XP_019620213.1| PREDICTED: neutral ceramidase-like isoform X2 [Branchiostoma
            belcheri]
          Length = 717

 Score =  567 bits (1462), Expect = 0.0
 Identities = 291/620 (46%), Positives = 394/620 (63%), Gaps = 8/620 (1%)
 Frame = -3

Query: 1927 RVVFVSADLAMGSLAVRRATLEKLKESFGDLYNDENVAISGTHTHAGPAGYLQYALYQIT 1748
            R VFVS D AM S  ++   ++KLK  FG+ YN+ NV +S  HTH+GPAG+LQY L+ +T
Sbjct: 96   RTVFVSVDCAMVSQILKIEVVKKLKPLFGNAYNESNVCLSAIHTHSGPAGFLQYVLFDVT 155

Query: 1747 SFGYFKENTEAISTGIYNSIVKAHNSIQPASIFVSTGELLNTNINRSPFSYEQNPEEERS 1568
            S G+ +E+  A+  GI  SI +AHN++ P  ++++ GEL + NINRSP +Y  NPE ER+
Sbjct: 156  SLGFVRESFNALVDGIVASIQRAHNNVVPGDLYLNQGELQDANINRSPTAYLNNPESERA 215

Query: 1567 QYKYNVDKEMILLKFTNEKGDVIGSINWFPVHPVSMMNNNTLVSGDNKGTASYFLEREYN 1388
            +Y  N DK M++LKF ++ G  +G I+WF VH  SM N N L+SGDNKG AS   E + N
Sbjct: 216  KYDANTDKNMVVLKFVDQHGTGLGMISWFAVHCTSMNNTNGLISGDNKGYASQLFEADMN 275

Query: 1387 NGTLPGEETIIHAFANSNLGDSSPNIFGPYCADTGLPCEYRTSTCNGKKETCFGRGYGYL 1208
             G+L G+ + + AFA SN GD SPN  GP+C DTGL C+  TSTCNGK E C   G G  
Sbjct: 276  PGSLAGQGSFVAAFAQSNEGDVSPNTRGPHCQDTGLACDLETSTCNGKSELCVSPGPGV- 334

Query: 1207 TGDDIYATRKIAELHVTKAKELIDT-AKTPITGSIDYKFTKVDIQNYNFTLNGK-TVSLC 1034
              D   +TR I     +KAKEL +  A+  ++G + +    VD+ +    +N   +   C
Sbjct: 335  --DMFDSTRIIGHKQYSKAKELYNADAQEKLSGPVQFALQFVDMSDVTVQINSSYSAKTC 392

Query: 1033 KAALGYSMIAGTTDGPGGFNFIQGDNSTGNPFWKLITRIIKQPTKETIECQRPKPIVLAT 854
            K A+GYS  AGTTDGPG F+F QGD + GNPFW  +  IIKQP+ E + CQ PKPI+L T
Sbjct: 393  KPAMGYSFAAGTTDGPGAFDFTQGD-TEGNPFWNFVRNIIKQPSAEEVACQAPKPILLPT 451

Query: 853  GEMRSPYDFTPSIIEIQLLKIGNFIICVVPGEFTTMSGRRLTKTVKNILMKKGVIDENGI 674
            GEM  PY + P I++IQLL+ G  ++  VPGEF+TMSGRRL  +++  ++ KG + E+  
Sbjct: 452  GEMTFPYAWQPDIVDIQLLRWGQLVVAAVPGEFSTMSGRRLRDSIQRAVVSKG-LPEDTE 510

Query: 673  VVVSGPSNSYTHYITTPEEYLVQRYEGGSTIYGPNTLNAYLQLYTDLSIALADNLYVPIG 494
            VVV+G SN+Y+ YITT EEY VQRYEG STIYGP+TL AY QLY+ L+  +     + IG
Sbjct: 511  VVVAGLSNTYSDYITTYEEYQVQRYEGASTIYGPHTLAAYQQLYSQLAQDMVMGADIDIG 570

Query: 493  PEAPDFTDKALNFVLPVIVDIPPLFKKFGDVTKDANKKYIRGETVEVEFVGGHPKNRIQL 314
            P  P+   + L+F+ PV++D  PLF  FG+V  DA   Y   ETV V F   HP+N +QL
Sbjct: 571  PSPPNLLSRQLSFLPPVVLDTTPLFTHFGEVITDAGSAYHTNETVSVRFHSAHPRNNLQL 630

Query: 313  EGSFLYVQRLENNNNWINFKNDGDITTQFKW------LGNSIVRITWEIGDDVEAGTYRI 152
            +GSFL V+R +++  +    ND    T +KW      +G+S   ITW I      GTYRI
Sbjct: 631  DGSFLTVERKKDDGTFEVVHNDASWDTMYKWKRTNVLVGHSEATITWTISPGTPPGTYRI 690

Query: 151  FYQGHHKQLGGKIVPEFGTT 92
             + GH K L G+I P  G++
Sbjct: 691  RHFGHSKNLVGEITPFVGSS 710


>ref|XP_022319861.1| neutral ceramidase-like [Crassostrea virginica]
          Length = 740

 Score =  565 bits (1457), Expect = 0.0
 Identities = 295/621 (47%), Positives = 393/621 (63%), Gaps = 8/621 (1%)
 Frame = -3

Query: 1927 RVVFVSADLAMGSLAVRRATLEKLKESFGDLYNDENVAISGTHTHAGPAGYLQYALYQIT 1748
            R+VFVS D  M S  ++   +++L+  +GDLYN+ NVAISGTHTH+GP G+ QY LY +T
Sbjct: 77   RIVFVSTDSCMQSQGLKLEIIKRLRSKYGDLYNERNVAISGTHTHSGPGGFHQYLLYDVT 136

Query: 1747 SFGYFKENTEAISTGIYNSIVKAHNSIQPASIFVSTGELLNTNINRSPFSYEQNPEEERS 1568
            S G+  E   ++  GI  SI KAHNS++P +++V+TGELL +NINRSP +Y  NP EER+
Sbjct: 137  SLGFVNETFVSLVEGIVASIDKAHNSMKPGNLYVNTGELLESNINRSPTAYLNNPAEERA 196

Query: 1567 QYKYNVDKEMILLKFTNEKGDVIGSINWFPVHPVSMMNNNTLVSGDNKGTASYFLEREYN 1388
            +YKY+VDK M +L+ T+ + + IG INWF VH  SM N N L+S DNKG A+   E + N
Sbjct: 197  KYKYDVDKNMTVLRMTDAQNNGIGMINWFAVHCTSMNNTNHLISSDNKGLAAQMFEADMN 256

Query: 1387 NGTLPGEETIIHAFANSNLGDSSPNIFGPYCADTGLPCEYRTSTCNGKKETCFGRGYGYL 1208
             G  PG+   + AFA SN GD SPN  GP+C DTG PC+  TSTCNG+ E C   G G  
Sbjct: 257  KGGFPGKGKFVAAFAQSNEGDVSPNTKGPHCMDTGKPCDVPTSTCNGRNELCVSPGPG-- 314

Query: 1207 TGDDIYATRKIAELHVTKAKELI-DTAKTPITGSIDYKFTKVDIQNYNFTLNGKT-VSLC 1034
              D   +TR IA     KAK L  D A   + G +D++ T VD+ +    +N  T V  C
Sbjct: 315  -KDMFDSTRIIASNQYKKAKILYSDPAGMKLEGPVDFRHTYVDMSSVMVQINQTTKVKTC 373

Query: 1033 KAALGYSMIAGTTDGPGGFNFIQGDNSTGNPFWKLITRIIKQPTKETIECQRPKPIVLAT 854
            K A+G+S  AGTTDGPG FNF QG  +T NPFW  I   +K+PT E + CQ PKPI+L T
Sbjct: 374  KPAMGFSFAAGTTDGPGAFNFTQG-ATTDNPFWDFIRDFLKKPTPEQLACQHPKPILLDT 432

Query: 853  GEMRSPYDFTPSIIEIQLLKIGNFIICVVPGEFTTMSGRRLTKTVKNILMKKGVIDENGI 674
            GEM +PY ++PSI+++Q+ +IG   I  VP EF+TMSGRR   ++   L   G    N +
Sbjct: 433  GEMTAPYAWSPSIVDLQIFRIGQLAIISVPAEFSTMSGRRTRDSITATLKAAG-FPANTV 491

Query: 673  VVVSGPSNSYTHYITTPEEYLVQRYEGGSTIYGPNTLNAYLQLYTDLSIALADNLYVPIG 494
             V++G +N Y  Y+TT EEY VQRYEG STIYGP+TL A++Q +  L+ ALA     P G
Sbjct: 492  SVIAGLTNDYADYVTTYEEYQVQRYEGASTIYGPHTLQAFIQEFNKLADALAKGTPSPKG 551

Query: 493  PEAPDFTDKALNFVLPVIVDIPPLFKKFGDVTKDANKKYIRGETVEVEFVGGHPKNRIQL 314
            P  P+  DK L+F+ PV+ D  P   KFGDV  DAN +Y +G++V+V F+G +P+N ++L
Sbjct: 552  PTPPNLLDKQLSFLPPVVFDHAPFGSKFGDVVVDANSQYKQGDSVKVTFIGANPRNNVKL 611

Query: 313  EGSFLYVQRLENNNNWINFKNDGDITTQFKW------LGNSIVRITWEIGDDVEAGTYRI 152
            E +FL V+ L+ +NNW     D    T+F+W      LG S V ITW+I      GTYRI
Sbjct: 612  EDTFLSVEMLQPDNNWKVVFTDSQWETKFEWKHTSLLLGESEVTITWDIPQSQAPGTYRI 671

Query: 151  FYQGHHKQLGGKIVPEFGTTS 89
             Y G  K L  KI    G ++
Sbjct: 672  QYFGDAKSLDQKITSFTGKST 692


>ref|XP_014680017.1| PREDICTED: neutral ceramidase-like [Priapulus caudatus]
          Length = 759

 Score =  562 bits (1448), Expect = 0.0
 Identities = 297/622 (47%), Positives = 382/622 (61%), Gaps = 8/622 (1%)
 Frame = -3

Query: 1927 RVVFVSADLAMGSLAVRRATLEKLKESFGDLYNDENVAISGTHTHAGPAGYLQYALYQIT 1748
            RVV+VSAD+AM S  ++   ++KLK  +GD+Y + NV +S  HTH+GP G+LQY LY IT
Sbjct: 79   RVVYVSADIAMVSQIIKIEVVKKLKTHYGDIYTEMNVCLSSIHTHSGPGGFLQYLLYDIT 138

Query: 1747 SFGYFKENTEAISTGIYNSIVKAHNSIQPASIFVSTGELLNTNINRSPFSYEQNPEEERS 1568
            S G+  E+T+AI  GI  SI  AH  + P  IF++ G LL++NINRSP +Y  NP+EER 
Sbjct: 139  SLGFVAESTDAIVNGIVKSIQIAHERLVPGDIFINRGTLLDSNINRSPTAYLNNPQEERD 198

Query: 1567 QYKYNVDKEMILLKFTNEKGDVIGSINWFPVHPVSMMNNNTLVSGDNKGTASYFLEREYN 1388
            +Y+Y+VDK+M++LK  N  G  IG I+WF VH  SM N N L+SGDNKG ASY  E+  N
Sbjct: 199  RYQYDVDKDMVVLKMVNSTGAAIGMISWFAVHCTSMNNTNHLISGDNKGYASYLFEQHMN 258

Query: 1387 NGTLPGEETIIHAFANSNLGDSSPNIFGPYCADTGLPCEYRTSTCNGKKETCFGRGYGYL 1208
             G+LPGE   + AFA +N GD SPN  GP+C DTGLPC   TSTCNGK E C   G G  
Sbjct: 259  PGSLPGEGDFVAAFAQANEGDVSPNTRGPHCLDTGLPCHMNTSTCNGKSELCVAFGPGVD 318

Query: 1207 TGDDIYATRKIAELHVTKAKELIDTAKTPITGSIDYKFTKVDIQNYNFTL-NGKTVSLCK 1031
              D   +TR I      KA  L + A   ++G +D+K   VD+ N    L +G     CK
Sbjct: 319  MAD---STRIIGNNQFIKALNLYNNATRKLSGPVDFKHQNVDMTNVQVNLSDGSQAHTCK 375

Query: 1030 AALGYSMIAGTTDGPGGFNFIQGDNSTGNPFWKLITRIIKQPTKETIECQRPKPIVLATG 851
             A+GYS  AGTTDGPG  +F QG  + GN  W LI   IK+P+ E   CQ PKPI+L TG
Sbjct: 376  PAMGYSFAAGTTDGPGAMDFTQG-TTQGNALWNLIRNFIKKPSAEQTACQLPKPILLDTG 434

Query: 850  EMRSPYDFTPSIIEIQLLKIGNFIICVVPGEFTTMSGRRLTKTVKNILMKKGVIDENGIV 671
            E+  PY + P I+E+QLL++G+FII  VPGEF+TMSGRR+   V   L + G   E    
Sbjct: 435  EISYPYSWQPDIVELQLLRVGDFIIVAVPGEFSTMSGRRVRSNVTATLAQHG-FPETTET 493

Query: 670  VVSGPSNSYTHYITTPEEYLVQRYEGGSTIYGPNTLNAYLQLYTDLSIALADNLYVPIGP 491
            V++G SN+Y+ YITT EEY VQRYEG STIYGP+TL AY+Q +  L+ A+A N  V  GP
Sbjct: 494  VIAGLSNTYSSYITTFEEYQVQRYEGASTIYGPHTLQAYIQHFNVLAAAIAQNSTVDKGP 553

Query: 490  EAPDFTDKALNFVLPVIVDIPPLFKKFGDVTKDANKKYIRGETVEVEFVGGHPKNRIQLE 311
              P   DK L FVLPV+ D   + K FGDV  DA  KY+   TV V FV GHP+N +   
Sbjct: 554  SVPYLRDKQLCFVLPVVYDGSGIGKSFGDVLTDAKPKYVVNTTVSVSFVAGHPRNNLMTG 613

Query: 310  GSFLYVQRLE-NNNNWINFKNDGDITTQFKW------LGNSIVRITWEIGDDVEAGTYRI 152
             +FL V+      + W     D    T+FKW      LG S   + W+I      G YR+
Sbjct: 614  ATFLTVEWWNPEQSTWHVAYTDSSWETRFKWTRTSSLLGKSQATVEWDIPAAAMPGVYRM 673

Query: 151  FYQGHHKQLGGKIVPEFGTTSN 86
             + GH K + G I P  GT+++
Sbjct: 674  RHFGHEKSVTGDIHPYAGTSAS 695


>ref|XP_013094635.1| PREDICTED: neutral ceramidase-like isoform X2 [Biomphalaria glabrata]
          Length = 664

 Score =  557 bits (1436), Expect = 0.0
 Identities = 292/620 (47%), Positives = 387/620 (62%), Gaps = 7/620 (1%)
 Frame = -3

Query: 1930 KRVVFVSADLAMGSLAVRRATLEKLKESFGDLYNDENVAISGTHTHAGPAGYLQYALYQI 1751
            KR VFVS D      AV+R  ++ LK  FGDLY + N+A+SGTHTH G  G+ QY L+ +
Sbjct: 31   KRTVFVSLDACWSPGAVKRLVVQILKNKFGDLYTERNIAVSGTHTHGGSGGFSQYLLFDL 90

Query: 1750 TSFGYFKENTEAISTGIYNSIVKAHNSIQPASIFVSTGELLNTNINRSPFSYEQNPEEER 1571
            T+ G+ ++N  A+  G   SI+ AH ++QPA IF+++GELL++NINRSP +Y  NP EER
Sbjct: 91   TALGFNQQNFGALVDGTLQSIINAHENLQPADIFMNSGELLDSNINRSPTAYLNNPAEER 150

Query: 1570 SQYKYNVDKEMILLKFTNEKGDVIGSINWFPVHPVSMMNNNTLVSGDNKGTASYFLEREY 1391
            S+YKY+VDKEM++LKF N+ G  IG I+WF VH  SM N N +++ DNKG AS   E+++
Sbjct: 151  SKYKYDVDKEMVVLKFVNQTGHGIGMISWFAVHGTSMNNTNKMLTSDNKGYASLLFEQQF 210

Query: 1390 NNGTLPGEETIIHAFANSNLGDSSPNIFGPYCADTGLPCEYRTSTCNGKKETCFGRGYGY 1211
            N G LPG+ T + AFA SNLGD SPN  GP+C DTGLPC+  TSTCNGK E C   G G 
Sbjct: 211  NPGALPGKGTFVAAFAQSNLGDVSPNTKGPHCLDTGLPCDAITSTCNGKNELCVAFGPG- 269

Query: 1210 LTGDDIYATRKIAELHVTKAKELIDTAKTPITGSIDYKFTKVDIQNYNFTL-NGKTVSLC 1034
               D   +T+ IA     KA EL ++A+  ITG +D++ + +++      L NG  V  C
Sbjct: 270  --KDMFESTQIIANNQYQKALELYNSAQIKITGPVDFRHSYINMTQQVVPLANGTKVQTC 327

Query: 1033 KAALGYSMIAGTTDGPGGFNFIQGDNSTGNPFWKLITRIIKQPTKETIECQRPKPIVLAT 854
            K A+GYS  AGTTDGPG F+F QG NS+ NPFW L+  +IK+PT+    C  PKPI+L T
Sbjct: 328  KPAMGYSFAAGTTDGPGAFDFKQGSNSS-NPFWNLVRDLIKEPTENQKRCHFPKPILLDT 386

Query: 853  GEMRSPYDFTPSIIEIQLLKIGNFIICVVPGEFTTMSGRRLTKTVKNILMKKGVIDENGI 674
            GE+  PY + P I++ Q+L+IG F+I  VPGEFTTMSGRR+   V   L  +G    +  
Sbjct: 387  GEISLPYFWQPQIVDNQILRIGQFVIIAVPGEFTTMSGRRMRDNVYLALTSQG-FPADTK 445

Query: 673  VVVSGPSNSYTHYITTPEEYLVQRYEGGSTIYGPNTLNAYLQLYTDLSIALADNLYVPIG 494
             V++G +N Y  YI T EEY  QRYE  STI+GP+TL AYLQ +  L+I +A     P G
Sbjct: 446  TVIAGLANEYADYIATYEEYQQQRYEAASTIFGPHTLEAYLQTFRSLAIQMAQGQPSPPG 505

Query: 493  PEAPDFTDKALNFVLPVIVDIPPLFKKFGDVTKDANKKYIRGETVEVEFVGGHPKNRIQL 314
            P  P+  DK ++ +  VI D  P   +FG V KDA   Y  G TV V FV  +P+N ++ 
Sbjct: 506  PTPPNQLDKQISLLPGVIFDSAPSGTQFGSVVKDAESTYTAGSTVTVTFVSANPRNDLRT 565

Query: 313  EGSFLYVQRLENNNNWINFKNDGDITTQFKW------LGNSIVRITWEIGDDVEAGTYRI 152
              +FL V+  EN +NW+    D +  T+FKW      LG+S   I WEI  D   G YRI
Sbjct: 566  GDTFLTVEHKENGDNWVVLYADANWETRFKWVQTSLILGHSQAEIMWEIPKDQIPGVYRI 625

Query: 151  FYQGHHKQLGGKIVPEFGTT 92
             + G  K + G   P  G T
Sbjct: 626  RHFGTSKSIIGSKTPFVGQT 645


>ref|XP_013094566.1| PREDICTED: neutral ceramidase-like isoform X1 [Biomphalaria glabrata]
          Length = 711

 Score =  557 bits (1436), Expect = 0.0
 Identities = 292/620 (47%), Positives = 387/620 (62%), Gaps = 7/620 (1%)
 Frame = -3

Query: 1930 KRVVFVSADLAMGSLAVRRATLEKLKESFGDLYNDENVAISGTHTHAGPAGYLQYALYQI 1751
            KR VFVS D      AV+R  ++ LK  FGDLY + N+A+SGTHTH G  G+ QY L+ +
Sbjct: 78   KRTVFVSLDACWSPGAVKRLVVQILKNKFGDLYTERNIAVSGTHTHGGSGGFSQYLLFDL 137

Query: 1750 TSFGYFKENTEAISTGIYNSIVKAHNSIQPASIFVSTGELLNTNINRSPFSYEQNPEEER 1571
            T+ G+ ++N  A+  G   SI+ AH ++QPA IF+++GELL++NINRSP +Y  NP EER
Sbjct: 138  TALGFNQQNFGALVDGTLQSIINAHENLQPADIFMNSGELLDSNINRSPTAYLNNPAEER 197

Query: 1570 SQYKYNVDKEMILLKFTNEKGDVIGSINWFPVHPVSMMNNNTLVSGDNKGTASYFLEREY 1391
            S+YKY+VDKEM++LKF N+ G  IG I+WF VH  SM N N +++ DNKG AS   E+++
Sbjct: 198  SKYKYDVDKEMVVLKFVNQTGHGIGMISWFAVHGTSMNNTNKMLTSDNKGYASLLFEQQF 257

Query: 1390 NNGTLPGEETIIHAFANSNLGDSSPNIFGPYCADTGLPCEYRTSTCNGKKETCFGRGYGY 1211
            N G LPG+ T + AFA SNLGD SPN  GP+C DTGLPC+  TSTCNGK E C   G G 
Sbjct: 258  NPGALPGKGTFVAAFAQSNLGDVSPNTKGPHCLDTGLPCDAITSTCNGKNELCVAFGPG- 316

Query: 1210 LTGDDIYATRKIAELHVTKAKELIDTAKTPITGSIDYKFTKVDIQNYNFTL-NGKTVSLC 1034
               D   +T+ IA     KA EL ++A+  ITG +D++ + +++      L NG  V  C
Sbjct: 317  --KDMFESTQIIANNQYQKALELYNSAQIKITGPVDFRHSYINMTQQVVPLANGTKVQTC 374

Query: 1033 KAALGYSMIAGTTDGPGGFNFIQGDNSTGNPFWKLITRIIKQPTKETIECQRPKPIVLAT 854
            K A+GYS  AGTTDGPG F+F QG NS+ NPFW L+  +IK+PT+    C  PKPI+L T
Sbjct: 375  KPAMGYSFAAGTTDGPGAFDFKQGSNSS-NPFWNLVRDLIKEPTENQKRCHFPKPILLDT 433

Query: 853  GEMRSPYDFTPSIIEIQLLKIGNFIICVVPGEFTTMSGRRLTKTVKNILMKKGVIDENGI 674
            GE+  PY + P I++ Q+L+IG F+I  VPGEFTTMSGRR+   V   L  +G    +  
Sbjct: 434  GEISLPYFWQPQIVDNQILRIGQFVIIAVPGEFTTMSGRRMRDNVYLALTSQG-FPADTK 492

Query: 673  VVVSGPSNSYTHYITTPEEYLVQRYEGGSTIYGPNTLNAYLQLYTDLSIALADNLYVPIG 494
             V++G +N Y  YI T EEY  QRYE  STI+GP+TL AYLQ +  L+I +A     P G
Sbjct: 493  TVIAGLANEYADYIATYEEYQQQRYEAASTIFGPHTLEAYLQTFRSLAIQMAQGQPSPPG 552

Query: 493  PEAPDFTDKALNFVLPVIVDIPPLFKKFGDVTKDANKKYIRGETVEVEFVGGHPKNRIQL 314
            P  P+  DK ++ +  VI D  P   +FG V KDA   Y  G TV V FV  +P+N ++ 
Sbjct: 553  PTPPNQLDKQISLLPGVIFDSAPSGTQFGSVVKDAESTYTAGSTVTVTFVSANPRNDLRT 612

Query: 313  EGSFLYVQRLENNNNWINFKNDGDITTQFKW------LGNSIVRITWEIGDDVEAGTYRI 152
              +FL V+  EN +NW+    D +  T+FKW      LG+S   I WEI  D   G YRI
Sbjct: 613  GDTFLTVEHKENGDNWVVLYADANWETRFKWVQTSLILGHSQAEIMWEIPKDQIPGVYRI 672

Query: 151  FYQGHHKQLGGKIVPEFGTT 92
             + G  K + G   P  G T
Sbjct: 673  RHFGTSKSIIGSKTPFVGQT 692


>ref|XP_013402701.1| neutral ceramidase isoform X2 [Lingula anatina]
          Length = 696

 Score =  554 bits (1428), Expect = 0.0
 Identities = 280/609 (45%), Positives = 385/609 (63%), Gaps = 8/609 (1%)
 Frame = -3

Query: 1927 RVVFVSADLAMGSLAVRRATLEKLKESFGDLYNDENVAISGTHTHAGPAGYLQYALYQIT 1748
            RVVFV+ D  M S  +++    KLK  +  LY++ NV +SGTHTH+GP GY +Y L+ +T
Sbjct: 76   RVVFVNVDACMISDIMKKKVANKLKTLYNGLYDETNVCVSGTHTHSGPGGYHRYVLFDVT 135

Query: 1747 SFGYFKENTEAISTGIYNSIVKAHNSIQPASIFVSTGELLNTNINRSPFSYEQNPEEERS 1568
            S G+ +E+ + +  GI  SI  AHN++   +I+++TG LLN+NINRSP +Y  NP  E++
Sbjct: 136  SLGFVEESLDPLVDGIVKSIQNAHNNMVAGNIYINTGVLLNSNINRSPTAYLNNPPGEKA 195

Query: 1567 QYKYNVDKEMILLKFTNEKGDVIGSINWFPVHPVSMMNNNTLVSGDNKGTASYFLEREYN 1388
            +Y YNVDK+M +LKF +  G  +G I+WF VH  SM N N  +SGDNKG A+   ERE N
Sbjct: 196  KYNYNVDKDMTVLKFVDGNGQPLGMISWFAVHCTSMNNTNGYISGDNKGYAAQLFEREMN 255

Query: 1387 NGTLPGEETIIHAFANSNLGDSSPNIFGPYCADTGLPCEYRTSTCNGKKETCFGRGYGYL 1208
             G+LPGE   I AFA SN GD SPN  G +C DTG PC+  TSTCNGK E C   G    
Sbjct: 256  PGSLPGEGKFIAAFAQSNEGDVSPNTKGAHCIDTGKPCDVSTSTCNGKPELCVASG---- 311

Query: 1207 TGDDIY-ATRKIAELHVTKAKELIDTAKTPITGSIDYKFTKVDIQNYNFTLNG-KTVSLC 1034
             G D+Y +T+ I +    KAKEL D A T +TG +DY+   VD+ N    ++     + C
Sbjct: 312  PGKDMYESTKIIGKKQYEKAKELFDGANTLLTGPVDYRHQFVDMSNQKVQIDATHYATTC 371

Query: 1033 KAALGYSMIAGTTDGPGGFNFIQGDNSTGNPFWKLITRIIKQPTKETIECQRPKPIVLAT 854
              A+GYS  AGTTDGPG F+F QG  +TGNPFW  +  I+ +P++  I+CQ PKPI+L T
Sbjct: 372  PPAMGYSFAAGTTDGPGSFDFTQG-TTTGNPFWNFVRNILSKPSRAQIQCQHPKPILLNT 430

Query: 853  GEMRSPYDFTPSIIEIQLLKIGNFIICVVPGEFTTMSGRRLTKTVKNILMKKGVIDENGI 674
            GEM  PY + PS++  Q+L+IG  +I  VPGEF+TMSGRRL   V  I  ++G +  N  
Sbjct: 431  GEMSFPYPWQPSVVPTQILRIGELMILAVPGEFSTMSGRRLRNAVTEIATQQG-LPSNTK 489

Query: 673  VVVSGPSNSYTHYITTPEEYLVQRYEGGSTIYGPNTLNAYLQLYTDLSIALADNLYVPIG 494
             VV+G SNSY  Y+ T EEY +QRYEG STIYGP+TL A++Q +  L+ A+A    +  G
Sbjct: 490  TVVAGLSNSYADYVVTYEEYQIQRYEGASTIYGPHTLLAFIQKFKGLTTAMAQGSTLSSG 549

Query: 493  PEAPDFTDKALNFVLPVIVDIPPLFKKFGDVTKDANKKYIRGETVEVEFVGGHPKNRIQL 314
            P  P+F  K ++F+ PV+ D PPLF+ FGDV K    KYI+G+ V+V F+  +P+N +  
Sbjct: 550  PSTPNFPSKLISFLTPVLHDSPPLFRSFGDVIKQPKSKYIQGDVVKVSFISANPRNNVMS 609

Query: 313  EGSFLYVQRLENNNNWINFKNDGDITTQFKW------LGNSIVRITWEIGDDVEAGTYRI 152
              SFL V++ +++ +W     D D  T + W      L  S+  I+W+I D    GTYRI
Sbjct: 610  GKSFLTVEKKQSDGSWKTVFTDADWETSYYWKRTSTILALSVSEISWKIPDQQPKGTYRI 669

Query: 151  FYQGHHKQL 125
             + G  K++
Sbjct: 670  RHFGTAKKM 678


>ref|XP_023932283.1| neutral ceramidase isoform X1 [Lingula anatina]
          Length = 699

 Score =  554 bits (1428), Expect = 0.0
 Identities = 280/609 (45%), Positives = 385/609 (63%), Gaps = 8/609 (1%)
 Frame = -3

Query: 1927 RVVFVSADLAMGSLAVRRATLEKLKESFGDLYNDENVAISGTHTHAGPAGYLQYALYQIT 1748
            RVVFV+ D  M S  +++    KLK  +  LY++ NV +SGTHTH+GP GY +Y L+ +T
Sbjct: 79   RVVFVNVDACMISDIMKKKVANKLKTLYNGLYDETNVCVSGTHTHSGPGGYHRYVLFDVT 138

Query: 1747 SFGYFKENTEAISTGIYNSIVKAHNSIQPASIFVSTGELLNTNINRSPFSYEQNPEEERS 1568
            S G+ +E+ + +  GI  SI  AHN++   +I+++TG LLN+NINRSP +Y  NP  E++
Sbjct: 139  SLGFVEESLDPLVDGIVKSIQNAHNNMVAGNIYINTGVLLNSNINRSPTAYLNNPPGEKA 198

Query: 1567 QYKYNVDKEMILLKFTNEKGDVIGSINWFPVHPVSMMNNNTLVSGDNKGTASYFLEREYN 1388
            +Y YNVDK+M +LKF +  G  +G I+WF VH  SM N N  +SGDNKG A+   ERE N
Sbjct: 199  KYNYNVDKDMTVLKFVDGNGQPLGMISWFAVHCTSMNNTNGYISGDNKGYAAQLFEREMN 258

Query: 1387 NGTLPGEETIIHAFANSNLGDSSPNIFGPYCADTGLPCEYRTSTCNGKKETCFGRGYGYL 1208
             G+LPGE   I AFA SN GD SPN  G +C DTG PC+  TSTCNGK E C   G    
Sbjct: 259  PGSLPGEGKFIAAFAQSNEGDVSPNTKGAHCIDTGKPCDVSTSTCNGKPELCVASG---- 314

Query: 1207 TGDDIY-ATRKIAELHVTKAKELIDTAKTPITGSIDYKFTKVDIQNYNFTLNG-KTVSLC 1034
             G D+Y +T+ I +    KAKEL D A T +TG +DY+   VD+ N    ++     + C
Sbjct: 315  PGKDMYESTKIIGKKQYEKAKELFDGANTLLTGPVDYRHQFVDMSNQKVQIDATHYATTC 374

Query: 1033 KAALGYSMIAGTTDGPGGFNFIQGDNSTGNPFWKLITRIIKQPTKETIECQRPKPIVLAT 854
              A+GYS  AGTTDGPG F+F QG  +TGNPFW  +  I+ +P++  I+CQ PKPI+L T
Sbjct: 375  PPAMGYSFAAGTTDGPGSFDFTQG-TTTGNPFWNFVRNILSKPSRAQIQCQHPKPILLNT 433

Query: 853  GEMRSPYDFTPSIIEIQLLKIGNFIICVVPGEFTTMSGRRLTKTVKNILMKKGVIDENGI 674
            GEM  PY + PS++  Q+L+IG  +I  VPGEF+TMSGRRL   V  I  ++G +  N  
Sbjct: 434  GEMSFPYPWQPSVVPTQILRIGELMILAVPGEFSTMSGRRLRNAVTEIATQQG-LPSNTK 492

Query: 673  VVVSGPSNSYTHYITTPEEYLVQRYEGGSTIYGPNTLNAYLQLYTDLSIALADNLYVPIG 494
             VV+G SNSY  Y+ T EEY +QRYEG STIYGP+TL A++Q +  L+ A+A    +  G
Sbjct: 493  TVVAGLSNSYADYVVTYEEYQIQRYEGASTIYGPHTLLAFIQKFKGLTTAMAQGSTLSSG 552

Query: 493  PEAPDFTDKALNFVLPVIVDIPPLFKKFGDVTKDANKKYIRGETVEVEFVGGHPKNRIQL 314
            P  P+F  K ++F+ PV+ D PPLF+ FGDV K    KYI+G+ V+V F+  +P+N +  
Sbjct: 553  PSTPNFPSKLISFLTPVLHDSPPLFRSFGDVIKQPKSKYIQGDVVKVSFISANPRNNVMS 612

Query: 313  EGSFLYVQRLENNNNWINFKNDGDITTQFKW------LGNSIVRITWEIGDDVEAGTYRI 152
              SFL V++ +++ +W     D D  T + W      L  S+  I+W+I D    GTYRI
Sbjct: 613  GKSFLTVEKKQSDGSWKTVFTDADWETSYYWKRTSTILALSVSEISWKIPDQQPKGTYRI 672

Query: 151  FYQGHHKQL 125
             + G  K++
Sbjct: 673  RHFGTAKKM 681


>ref|XP_013402699.1| neutral ceramidase [Lingula anatina]
          Length = 729

 Score =  555 bits (1430), Expect = 0.0
 Identities = 291/624 (46%), Positives = 392/624 (62%), Gaps = 12/624 (1%)
 Frame = -3

Query: 1927 RVVFVSADLAMGSLAVRRATLEKLKESFGDLYNDENVAISGTHTHAGPAGYLQYALYQIT 1748
            RVVFV+ D  M S  ++   ++KL+  +  LYND NV +SG HTH+GP G+ QY L+ +T
Sbjct: 78   RVVFVNVDACMISEILKIQVVQKLQTLYHGLYNDSNVCLSGIHTHSGPGGFHQYVLFDVT 137

Query: 1747 SFGYFKENTEAISTGIYNSIVKAHNSIQPASIFVSTGELLNTNINRSPFSYEQNPEEERS 1568
            S G+ KE+ +++  GI  SI  AHN++   +I+++TGELL++NINRSP +Y  NP EE++
Sbjct: 138  SLGFVKESLDSLVNGIVKSIQNAHNNMVAGNIYINTGELLDSNINRSPSAYLNNPAEEKA 197

Query: 1567 QYKYNVDKEMILLKFTNEKGDVIGSINWFPVHPVSMMNNNTLVSGDNKGTASYFLEREYN 1388
            +YKYNVDK M +LKF +E    +G I+WF VH  SM N N  +SGDNKG A+   ERE N
Sbjct: 198  RYKYNVDKNMTVLKFVDENAKPLGMISWFAVHCTSMNNTNGYISGDNKGYAAQLFEREMN 257

Query: 1387 NGTLPGEETIIHAFANSNLGDSSPNIFGPYCADTGLPCEYRTSTCNGKKETCFGRGYGYL 1208
             G+LPGE   + AFA SN GD SPN  GP+C +TG PC+  TSTC GK E C   G    
Sbjct: 258  PGSLPGEGKFVAAFAQSNEGDVSPNTKGPHCINTGKPCDILTSTCEGKNELCIASG---- 313

Query: 1207 TGDDIY-ATRKIAELHVTKAKELIDTAKTPITGSIDYK--FTKVDIQ--NYNFTLNGKTV 1043
             G D+Y +T+ I      KAKEL  +A T +TG +DY+  F  + IQ    N T N  T 
Sbjct: 314  PGRDMYESTKIIGGNQFKKAKELFHSASTLLTGPVDYRHQFVNMSIQIVQVNATHNATT- 372

Query: 1042 SLCKAALGYSMIAGTTDGPGGFNFIQGDNSTGNPFWKLITRIIKQPTKETIECQRPKPIV 863
              C  A+GYS  AGTTDGPG F+F QG ++T NPFW +I   + +PT + I+CQ PKPI+
Sbjct: 373  --CPPAMGYSFAAGTTDGPGMFDFTQG-STTSNPFWNVIRDFLSKPTPQQIKCQHPKPIL 429

Query: 862  LATGEMRSPYDFTPSIIEIQLLKIGNFIICVVPGEFTTMSGRRLTKTVKNILMKKGVIDE 683
            L TGE+  PY + PS++  Q+L+IG  +I  VPGEF+TMSGRRL   +  I ++ G    
Sbjct: 430  LNTGEISFPYPWQPSVVPTQILRIGELMILAVPGEFSTMSGRRLRNAITEIAIQHG-FPS 488

Query: 682  NGIVVVSGPSNSYTHYITTPEEYLVQRYEGGSTIYGPNTLNAYLQLYTDLSIALADNLYV 503
            N   VV+G SN+Y  YI T EEY +QRYEG STI+GP+TL AY+Q +  L++A+A    V
Sbjct: 489  NTTTVVAGLSNAYADYIATYEEYQIQRYEGASTIFGPHTLQAYIQKFKTLTVAMARGSPV 548

Query: 502  PIGPEAPDFTDKALNFVLPVIVDIPPLFKKFGDVTKDANKKYIRGETVEVEFVGGHPKNR 323
            P+GP  P+F  +  +F+ PV+ D  P+ + FGDV K  N KY+ G TVEV F+  +P+N 
Sbjct: 549  PVGPSPPNFMKELFSFLPPVLFDHAPMGQNFGDVVKKPNPKYMPGGTVEVSFISANPRNN 608

Query: 322  IQLEGSFLYVQRLENNNNWINFKNDGDITTQFKW------LGNSIVRITWEIGDDVEAGT 161
            +    SFL V+  +++ +W     D D  T + W      LG SI  ITW I D    GT
Sbjct: 609  LMSGKSFLTVEMKQSDGSWKTMFTDADWETSYHWERTSTILGESISVITWNIPDQQMPGT 668

Query: 160  YRIFYQGHHK-QLGGKIVPEFGTT 92
            YRI + G  K  +GG I P  G+T
Sbjct: 669  YRIRHFGSSKSMIGGSITPFEGST 692


>gb|KVI11923.1| Neutral/alkaline nonlysosomal ceramidase [Cynara cardunculus var.
            scolymus]
          Length = 727

 Score =  547 bits (1410), Expect = 0.0
 Identities = 282/638 (44%), Positives = 392/638 (61%), Gaps = 33/638 (5%)
 Frame = -3

Query: 1927 RVVFVSADLAMGSLAVRRATLEKLKESFGDLYNDENVAISGTHTHAGPAGYLQYALYQIT 1748
            RVVFV+ D  M S  V    LE+LK  +G+LY ++NVAISG HTHAGP GYLQY +Y +T
Sbjct: 86   RVVFVNLDACMASQLVTIKVLERLKARYGNLYTEKNVAISGIHTHAGPGGYLQYVVYIVT 145

Query: 1747 SFGYFKENTEAISTGIYNSIVKAHNSIQPASIFVSTGELLNTNINRSPFSYEQNPEEERS 1568
            S G+ +++ + I  GI  SI++AH +++  S++V+ GE+L+  +NRSP SY  NP  ERS
Sbjct: 146  SLGFVRQSFDVIVDGIEQSIMRAHENLRAGSVYVNKGEILDAGVNRSPSSYLNNPAAERS 205

Query: 1567 QYKYNVDKEMILLKFTNEKGDVIGSINWFPVHPVSMMNNNTLVSGDNKGTASYFLEREYN 1388
            +YKY+VDKE+ LLKF +++   +G+ NWF  H  SM   N L+SGDNKGTA+  +E  ++
Sbjct: 206  KYKYDVDKEITLLKFVDDQWGPVGAFNWFATHGTSMSRTNELISGDNKGTAARLMEDWFD 265

Query: 1387 ---------------NGTLPGEE-----TIIHAFANSNLGDSSPNIFGPYCADTGLPCEY 1268
                           +  +PG +       + AF  SN GD SPN+ G +C DTGLPC++
Sbjct: 266  QKSVGGIANEIPRRVSNIVPGTQGNHRPKFVSAFCQSNCGDVSPNVLGAFCTDTGLPCDF 325

Query: 1267 RTSTCNGKKETCFGRGYGYLTGDDIYATRKIAELHVTKAKELIDTAKTPITGSIDYKFTK 1088
              STC GK E C+GRG GY   D+  +TR I E    KA EL ++A   + G ID++ T 
Sbjct: 326  NHSTCGGKNELCYGRGPGY--PDEFESTRIIGERQFKKATELFNSASQKLNGKIDFRHTY 383

Query: 1087 VDIQNYNFTL-----NGKTVSLCKAALGYSMIAGTTDGPGGFNFIQGDNSTGNPFWKLIT 923
            +D      TL       +TV  C AA+G++  AGTTDGPG F+F QGD+S GN FWKL+ 
Sbjct: 384  LDFSQLEVTLPKQGGGSETVKTCPAAMGFAFAAGTTDGPGAFDFKQGDDS-GNAFWKLVR 442

Query: 922  RIIKQPTKETIECQRPKPIVLATGEMRSPYDFTPSIIEIQLLKIGNFIICVVPGEFTTMS 743
             ++K P+KE  +CQ+PKPI+L TGEM+ PYD+ PSI+ IQ+LKIG  +I  VPGEFTTM+
Sbjct: 443  NVLKTPSKEQTDCQQPKPILLDTGEMKQPYDWAPSILPIQILKIGQLVILSVPGEFTTMA 502

Query: 742  GRRLTKTVKNILMKKGVIDENGIVVVSGPSNSYTHYITTPEEYLVQRYEGGSTIYGPNTL 563
            GRRL   V        V  E   VV++G +N+Y+ Y+TT EEY +QRYEG ST+YGP+TL
Sbjct: 503  GRRLRDAV------GAVFKEKVQVVIAGLTNTYSQYVTTLEEYKMQRYEGASTLYGPHTL 556

Query: 562  NAYLQLYTDLSIALADNLYVPIGPEAPDFTDKALNFVLPVIVDIPPLFKKFGDVTKD--A 389
            +AY+Q +T L+ A+     V  GP+ PD  +K ++ + PV+VD  PL   FGDV+ +   
Sbjct: 557  SAYIQEFTKLATAIVSGKPVEAGPQPPDLLNKQISLLAPVVVDSTPLGVGFGDVSTNIPR 616

Query: 388  NKKYIRGETVEVEFVGGHPKNRIQLEGSFLYVQRLENNNNWINFKNDGDITTQFKW---- 221
            N  + +G+TV V F    P+N +  EG+F  V+ L+  + W+   +D DI  +FKW    
Sbjct: 617  NSTFKKGDTVSVVFWSACPRNDLMTEGTFALVELLQGQDTWVPAYDDDDICLRFKWSRPS 676

Query: 220  --LGNSIVRITWEIGDDVEAGTYRIFYQGHHKQLGGKI 113
                 S   I W +      G YR+ + G  K L G I
Sbjct: 677  KLSAQSHATIEWRVPQSAVPGVYRVSHFGASKSLFGSI 714


>ref|XP_005100690.1| PREDICTED: neutral ceramidase-like [Aplysia californica]
          Length = 696

 Score =  544 bits (1402), Expect = 0.0
 Identities = 286/620 (46%), Positives = 386/620 (62%), Gaps = 7/620 (1%)
 Frame = -3

Query: 1927 RVVFVSADLAMGSLAVRRATLEKLKESFGDLYNDENVAISGTHTHAGPAGYLQYALYQIT 1748
            RV+FV+ D A    AV+R  ++KLK+ FG+LY D+NV ISGTHTH+G  GY QY L+ IT
Sbjct: 74   RVIFVNLDAAWAGGAVKRQVVQKLKKRFGNLYTDKNVCISGTHTHSGMGGYSQYLLFDIT 133

Query: 1747 SFGYFKENTEAISTGIYNSIVKAHNSIQPASIFVSTGELLNTNINRSPFSYEQNPEEERS 1568
            + G+  +  EA+  GI  SIVKAH+S+QPA ++V+ GELL +NINRSP +Y  NPE ER+
Sbjct: 134  ALGFNHQTFEALVDGIVVSIVKAHDSMQPADLYVNKGELLESNINRSPTAYLNNPEAERA 193

Query: 1567 QYKYNVDKEMILLKFTNEKGDVIGSINWFPVHPVSMMNNNTLVSGDNKGTASYFLEREYN 1388
            +Y +NVDK+M++LK  +  G  IG I+WF VH  SM N N ++S DNKG A+   E  +N
Sbjct: 194  KYTHNVDKDMVVLKIVSSSGVDIGMISWFAVHCTSMNNTNQMISSDNKGYAAQQFENMFN 253

Query: 1387 NGTLPGEETIIHAFANSNLGDSSPNIFGPYCADTGLPCEYRTSTCNGKKETCFGRGYGYL 1208
             G+ PG+   + AFA SN GD SPN  GP+C DTG  C+  TSTCN + E C   G G  
Sbjct: 254  PGSAPGKGPFVAAFAQSNEGDVSPNTRGPHCLDTGKECDVPTSTCNDRNELCVAFGPG-- 311

Query: 1207 TGDDIYATRKIAELHVTKAKELIDTAKTPITGSIDYKFTKVDIQNYNFTL-NGKTVSLCK 1031
              D   +T+ I      KA EL ++A   ++G +D++ +  D+   N +L NG  V  CK
Sbjct: 312  -KDMFESTQIIGNNQFKKAVELYNSASFKLSGPVDFRHSFADMTIQNVSLSNGSKVQTCK 370

Query: 1030 AALGYSMIAGTTDGPGGFNFIQGDNSTGNPFWKLITRIIKQPTKETIECQRPKPIVLATG 851
             ++GYS  AGTTDGPG F+F QG  +T NPFW  +  +I+ P+ E ++CQ PKPI+L TG
Sbjct: 371  PSMGYSFAAGTTDGPGAFDFKQG-TTTSNPFWNFVRDLIEDPSPELVKCQEPKPILLPTG 429

Query: 850  EMRSPYDFTPSIIEIQLLKIGNFIICVVPGEFTTMSGRRLTKTVKNILMKKGVIDENGIV 671
            E+  PY + P I++ QLL++G F+I  VPGEF+TMSGRR+   V +IL++ G    N   
Sbjct: 430  EITKPYLWQPQIVDTQLLRLGQFVIIAVPGEFSTMSGRRMRDAVSSILIQGG-FPANTST 488

Query: 670  VVSGPSNSYTHYITTPEEYLVQRYEGGSTIYGPNTLNAYLQLYTDLSIALADNLYVPIGP 491
            V+ G  N Y  YITT EEY +QRYEG ST YGP TL AY+QLY  L+ A+A     P GP
Sbjct: 489  VIGGLCNEYADYITTYEEYQIQRYEGASTTYGPYTLAAYIQLYRQLASAMAKGTPSPDGP 548

Query: 490  EAPDFTDKALNFVLPVIVDIPPLFKKFGDVTKDANKKYIRGETVEVEFVGGHPKNRIQLE 311
              P+  D  LNFV  VI D+ P  ++FG V +DAN  Y  G  V V F   +P+N ++  
Sbjct: 549  TPPNLLDVQLNFVPGVIFDLAPSGEEFGSVLQDANPSYRAGSQVTVRFQSANPRNNLRTN 608

Query: 310  GSFLYVQRLENNNNWINFKNDGDITTQFKW------LGNSIVRITWEIGDDVEAGTYRIF 149
            G+FL V+R + +  WI   +D    T+F W      LG S   I W+I    ++GTYRI 
Sbjct: 609  GTFLSVERKDESGRWIIAFSDSYWETRFHWIRTETFLGYSEALIIWDIPIGQKSGTYRIQ 668

Query: 148  YQGHHKQLGGKIVPEFGTTS 89
            + G  K + G +    GTTS
Sbjct: 669  HFGTSKTVTGTLTNFVGTTS 688


>ref|XP_002989773.1| hypothetical protein SELMODRAFT_130277 [Selaginella moellendorffii]
 gb|EFJ09250.1| hypothetical protein SELMODRAFT_130277 [Selaginella moellendorffii]
          Length = 713

 Score =  541 bits (1395), Expect = 0.0
 Identities = 284/620 (45%), Positives = 388/620 (62%), Gaps = 15/620 (2%)
 Frame = -3

Query: 1927 RVVFVSADLAMGSLAVRRATLEKLKESFGDLYNDENVAISGTHTHAGPAGYLQYALYQIT 1748
            R+V+VS D  M S AV  A L KLK  +GDLY ++NVA+SG HTH+GP GYLQY LY IT
Sbjct: 87   RIVYVSLDACMASQAVTTAVLSKLKTRYGDLYTEKNVALSGIHTHSGPGGYLQYLLYSIT 146

Query: 1747 SFGYFKENTEAISTGIYNSIVKAHNSIQPASIFVSTGELLNTNINRSPFSYEQNPEEERS 1568
            S G+ K++ +AI  G   SI +AHN+++P SIFV+ GE+L+ NINRSP +Y  NP EER 
Sbjct: 147  SLGFVKQSFDAIVDGAVASITQAHNNLKPGSIFVNEGEILDANINRSPSAYLNNPAEERK 206

Query: 1567 QYKYNVDKEMILLKFTNEKGDVIGSINWFPVHPVSMMNNNTLVSGDNKGTASYFLEREY- 1391
            +YKY+VDK M+LLK  + +   +G++NWFPVH  SM N NTLVSGDNKG AS F+E  + 
Sbjct: 207  RYKYDVDKSMLLLKLVDAQRGPVGTVNWFPVHCTSMNNTNTLVSGDNKGAASRFMEDWFD 266

Query: 1390 ----------NNGTLPGEETIIHAFANSNLGDSSPNIFGPYCADTGLPCEYRTSTCNGKK 1241
                      N   +  + + + AFA +N GD SPN  G +C DT L C++  STCNG  
Sbjct: 267  HRSVKREPSANTSRVRSKTSFVAAFAQTNEGDVSPNTLGAFCGDTNLRCDFNHSTCNGSN 326

Query: 1240 ETCFGRGYGYLTGDDIYATRKIAELHVTKAKELIDTAKTPITGSIDYKFTKVDIQNYNFT 1061
            E C  RG GY   D   +T  IA   + +A EL   AK  + G ++Y+ + VD    N +
Sbjct: 327  ELCIARGPGY--PDHFASTEIIATRQMERAIELFANAKDLLKGPVNYRQSYVDFT--NIS 382

Query: 1060 LNGKTVSLCKAALGYSMIAGTTDGPGGFNFIQGDNSTGNPFWKLITRIIKQPTKETIECQ 881
            +  ++ + C AA+G+S  AGTTDGPG F+F QGD + GNPFWK +  ++++PT++ + CQ
Sbjct: 383  IAAQSATTCPAAMGFSFAAGTTDGPGAFDFKQGD-TDGNPFWKAVRDLLRKPTEKQVACQ 441

Query: 880  RPKPIVLATGEMRSPYDFTPSIIEIQLLKIGNFIICVVPGEFTTMSGRRLTKTVKNILMK 701
             PKP++L TGEM  PYD+ P+I+ IQ+L++G   I  VP EFTTM+GRRL   VK  L++
Sbjct: 442  SPKPVLLDTGEMFFPYDWAPAILPIQILQVGQLFILSVPSEFTTMAGRRLKDAVKATLVE 501

Query: 700  K--GVIDENGIVVVSGPSNSYTHYITTPEEYLVQRYEGGSTIYGPNTLNAYLQLYTDLSI 527
            K  G  D+   +V+SG +N+Y+ Y+TT EEY +QRYEG ST+YGP+TL+AY+Q +  L+ 
Sbjct: 502  KSNGKYDKEVRIVISGLTNAYSSYVTTLEEYQIQRYEGASTLYGPHTLSAYIQEFKKLAE 561

Query: 526  ALADNLYVPIGPEAPDFTDKALNFVLPVIVDIPPLFKKFGDVTKDA--NKKYIRGETVEV 353
            AL  +  V  GP  PD   K ++ +  VI D  P   KFGDV++D   N  +  G+TVE 
Sbjct: 562  ALVLDTQVAKGPSPPDLISKQISLLPEVIPDTTPAGIKFGDVSRDVARNASFRAGDTVEA 621

Query: 352  EFVGGHPKNRIQLEGSFLYVQRLENNNNWINFKNDGDITTQFKWLGNSIVRITWEIGDDV 173
             F  G P+N +  E S+  V+       W    +D D + QF W   S   I W++  D 
Sbjct: 622  TFWSGSPRNNLMTEASYTMVEFQSAPGVWTPAYDDDDWSVQFVWKRPS-ATIKWKVPKDA 680

Query: 172  EAGTYRIFYQGHHKQLGGKI 113
             AGTYR+   G  K L GKI
Sbjct: 681  LAGTYRLRLFGASKALMGKI 700


>ref|XP_002964917.1| hypothetical protein SELMODRAFT_167350 [Selaginella moellendorffii]
 gb|EFJ33755.1| hypothetical protein SELMODRAFT_167350 [Selaginella moellendorffii]
          Length = 735

 Score =  540 bits (1391), Expect = 0.0
 Identities = 293/661 (44%), Positives = 403/661 (60%), Gaps = 46/661 (6%)
 Frame = -3

Query: 1930 KRVVFVSADLAMGSLAVRRATLEKLKES-FGDLYNDENVAISGTHTHAGPAGYLQYALYQ 1754
            +RV FV+ D  MGS A+    L KLK+  +GD Y+++NV ISG HTH+GP GYLQY LY 
Sbjct: 73   RRVAFVNVDSCMGSQAITLKVLSKLKDRRYGDTYSEKNVIISGIHTHSGPGGYLQYVLYI 132

Query: 1753 ITSFGYFKENTEAISTGIYNSIVKAHNSIQPASIFVSTGELLNTNINRSPFSYEQNPEEE 1574
            +TS G+ K++  A+  GI++SIV+AH +++P SI ++ GELL+ NINRSP +Y  NP EE
Sbjct: 133  VTSIGFVKQSFNALVDGIFSSIVQAHENLRPGSILLNEGELLDANINRSPSAYLNNPVEE 192

Query: 1573 RSQYKYNVDKEMILLKFTNEKGDVIGSINWFPVHPVSMMNNNTLVSGDNKGTASYFLERE 1394
            R +YKYNVDK M+LLKF + K   IG+ +WFPVH  SM   N L+SGDNKG A++F+E  
Sbjct: 193  RKRYKYNVDKNMVLLKFLDSKRAPIGAFSWFPVHCTSMNRTNELISGDNKGAAAHFMEAW 252

Query: 1393 Y----------------------------NNGTLPGEET--IIHAFANSNLGDSSPNIFG 1304
            +                            N   L G+ +   I AF+ SN GD SPN  G
Sbjct: 253  FDKQLEQEDPTIEMLGKPGWTMNASVTIRNRRRLVGDSSSPFIAAFSQSNEGDVSPNTLG 312

Query: 1303 PYCADTGLPCEYRTSTCNGKKETCFGRGYGYLTGDDIYATRKIAELHVTKAKELIDTAKT 1124
             +CAD+ + CE+  STC+G+ E C GRG GY   D   +T+ IA+  + KA EL  +AK 
Sbjct: 313  AFCADSTVACEFNHSTCDGRNEQCIGRGPGY--PDHFASTKIIAQKQLQKAIELFRSAKE 370

Query: 1123 PITGSIDYKFTKVDIQNYNFTL---NG--KTVSLCKAALGYSMIAGTTDGPGGFNFIQGD 959
             + G ++YK T VD      TL   NG   TV+ C AA+G+S  AGTTDGPG F+F QGD
Sbjct: 371  QVVGRVNYKQTFVDFTRLKVTLTAANGTTSTVTTCPAAVGFSFAAGTTDGPGAFDFTQGD 430

Query: 958  NSTGNPFWKLITRIIKQPTKETIECQRPKPIVLATGEMRSPYDFTPSIIEIQLLKIGNFI 779
             + GN FW+++   +K P K  ++CQ PKPI++ TGEM  PYD+ PS++ IQ+ +IG  I
Sbjct: 431  -TKGNAFWRIVRAALKTPNKAQVDCQYPKPILIDTGEMTFPYDWAPSVLPIQISQIGQLI 489

Query: 778  ICVVPGEFTTMSGRRLTKTVKNILMKK--GVIDENGIVVVSGPSNSYTHYITTPEEYLVQ 605
            I  VP EF+TM+GRRL   VK  L+ K  G       VV++G SN Y+ Y+TT EEY +Q
Sbjct: 490  ILSVPAEFSTMAGRRLRDAVKETLIAKGRGQFGPKTRVVIAGLSNDYSQYVTTFEEYQIQ 549

Query: 604  RYEGGSTIYGPNTLNAYLQLYTDLSIALADNLYVPIGPEAPDFTDKALNFVLPVIVDIPP 425
            RYEG ST++GP+TL+ YLQ +  L+IALA+N  V  GP  PD  DK L  + PV++D  P
Sbjct: 550  RYEGASTLFGPHTLSGYLQEFRKLAIALAENSNVDSGPSPPDLLDKQLELLPPVVMDTTP 609

Query: 424  LFKKFGDVTKDANK--KYIRGETVEVEFVGGHPKNRIQLEGSFLYVQRLENNNNWINFKN 251
            +   FGD   +  +   Y  G+ VEV F  G P+N +  E SF  V+  +++ +W +  +
Sbjct: 610  VGVDFGDAKNNVKRGASYRPGDVVEVVFWTGCPRNDLLTEKSFSSVEIEQSDGSWRSLYD 669

Query: 250  DGDITTQFKW------LGNSIVRITWEIGDDVEAGTYRIFYQGHHKQLGGKIVPEFGTTS 89
            D D + +F W         S   I WEI  +V+AGTYRI + G  K L G + P  G+++
Sbjct: 670  DNDWSVRFLWRRPSSLSSRSYATIRWEIPQEVKAGTYRISHFGASKSLFGSVRPFSGSSN 729

Query: 88   N 86
            +
Sbjct: 730  S 730