BLASTX 2.2.26 [Sep-21-2011]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= Ophiopogon25_contig00042613
         (1670 letters)

Database: All non-redundant GenBank CDS
translations+PDB+SwissProt+PIR+PRF excluding environmental samples
from WGS projects 
           149,584,005 sequences; 54,822,741,787 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

dbj|GBC46544.1| 3-phosphoinositide dependent protein kinase-1 [R...   868   0.0  
gb|PKC07109.1| Pkinase-domain-containing protein [Rhizophagus ir...   657   0.0  
gb|ORY01027.1| kinase-like protein [Basidiobolus meristosporus C...   497   e-168
ref|XP_004346099.1| PkB kinase [Capsaspora owczarzaki ATCC 30864...   453   e-150
ref|XP_021089426.1| 3-phosphoinositide-dependent protein kinase ...   421   e-138
ref|XP_006979015.1| PREDICTED: 3-phosphoinositide-dependent prot...   421   e-138
ref|XP_006913986.1| PREDICTED: 3-phosphoinositide-dependent prot...   422   e-138
gb|ELK10765.1| 3-phosphoinositide-dependent protein kinase 1 [Pt...   422   e-138
ref|XP_007606614.1| PREDICTED: 3-phosphoinositide-dependent prot...   421   e-138
ref|XP_008061434.1| 3-phosphoinositide-dependent protein kinase ...   420   e-138
ref|XP_005081691.1| 3-phosphoinositide-dependent protein kinase ...   421   e-138
ref|XP_020024613.1| 3-phosphoinositide-dependent protein kinase ...   419   e-138
ref|XP_015977724.1| PREDICTED: 3-phosphoinositide-dependent prot...   419   e-137
ref|XP_008843764.1| PREDICTED: 3-phosphoinositide-dependent prot...   419   e-137
ref|XP_014442528.1| PREDICTED: 3-phosphoinositide-dependent prot...   419   e-137
ref|XP_005349254.1| PREDICTED: 3-phosphoinositide-dependent prot...   419   e-137
ref|XP_012867072.1| PREDICTED: 3-phosphoinositide-dependent prot...   418   e-137
ref|XP_020024612.1| 3-phosphoinositide-dependent protein kinase ...   419   e-137
ref|NP_001273591.1| 3-phosphoinositide-dependent protein kinase ...   418   e-137
gb|AAL47185.1| phosphoinositide-dependent protein kinase-1 beta ...   418   e-137

>dbj|GBC46544.1| 3-phosphoinositide dependent protein kinase-1 [Rhizophagus
            irregularis DAOM 181602]
 gb|PKK72345.1| Pkinase-domain-containing protein [Rhizophagus irregularis]
 gb|PKY16403.1| Pkinase-domain-containing protein [Rhizophagus irregularis]
 gb|PKY50811.1| Pkinase-domain-containing protein [Rhizophagus irregularis]
 gb|POG77894.1| kinase-like domain-containing protein [Rhizophagus irregularis DAOM
            181602=DAOM 197198]
          Length = 528

 Score =  868 bits (2244), Expect = 0.0
 Identities = 428/459 (93%), Positives = 431/459 (93%)
 Frame = +3

Query: 3    TLGEGSYSTVVAARDRSNNREYAVXXXXXXXXXXXXXXXYVNIEKNTLNKMNHPGIVRLY 182
            TLGEGSYSTVVAARDRSNNREYAV               YVNIEKNTLNKMNHPGIVRLY
Sbjct: 70   TLGEGSYSTVVAARDRSNNREYAVKILDKKHIIKEKKVKYVNIEKNTLNKMNHPGIVRLY 129

Query: 183  YTFQDPDSLYFVLDHAKNGELLTFIKKLGSFDMDCTKFYASQILSAIEYMHSQGVIHRDL 362
            YTFQDPDSLYFVLDHAKNGELLTFIKKLGSFDMDCTKFYASQILSAIEYMHSQGVIHRDL
Sbjct: 130  YTFQDPDSLYFVLDHAKNGELLTFIKKLGSFDMDCTKFYASQILSAIEYMHSQGVIHRDL 189

Query: 363  KPENILLDEKMHVKVTDFGTAKILEQNADGEDDDRANSFVGTAEYVSPELLKEKAACKSS 542
            KPENILLDEKMHVKVTDFGTAKILEQNA+GE+DDRANSFVGTAEYVSPELLKEKAACKSS
Sbjct: 190  KPENILLDEKMHVKVTDFGTAKILEQNAEGEEDDRANSFVGTAEYVSPELLKEKAACKSS 249

Query: 543  DFWALGCIIYQLIAGRPPFKGANEYRTFQKIVNLEYSFPDGFPPVARDLVQKLLVLNPSE 722
            DFWALGCIIYQLIAGRPPFKGANEYRTFQKIVNLEYSFPDGFPPVARDLVQKLLVLNPSE
Sbjct: 250  DFWALGCIIYQLIAGRPPFKGANEYRTFQKIVNLEYSFPDGFPPVARDLVQKLLVLNPSE 309

Query: 723  RLGSGGKAGVERLKAHPFFQGIDWDTLWQQXXXXXXXXXXXXXKHNDPEFRTPTNAYLPK 902
            RLGSGGKAGVERLKAHPFFQGIDWDTLWQQ             KHNDPEFRTPTNAYLPK
Sbjct: 310  RLGSGGKAGVERLKAHPFFQGIDWDTLWQQPAPNLLPYLPPNPKHNDPEFRTPTNAYLPK 369

Query: 903  LSDNSEVNGSPIATGLRQNDPFRLESWAGGDDSSDKVDPEKVKKLEEQKRTSAQWIPFIL 1082
            LSDNSEVNGSPIATGLRQNDPFRLESWAGGDDSSDKVDPEKVKKLEEQKRTSAQW+PFIL
Sbjct: 370  LSDNSEVNGSPIATGLRQNDPFRLESWAGGDDSSDKVDPEKVKKLEEQKRTSAQWLPFIL 429

Query: 1083 KSELIIKTGPINKRKGFFSKKRTLILTDFPRLIYVDQEKNSQKGEIYWSSRMVVELKNKR 1262
            KSELIIKTGPINKRKGFFSKKRTLILTDFPRLIYVDQEKNSQKGEIYWSSRMVVELKNKR
Sbjct: 430  KSELIIKTGPINKRKGFFSKKRTLILTDFPRLIYVDQEKNSQKGEIYWSSRMVVELKNKR 489

Query: 1263 NFFIHTPRKTYYFEDPNNAAHEWVTKINELLVANYGEMF 1379
            NFFIHTPRKTYYFEDPNNAAHEWVTKINELLVANYGEMF
Sbjct: 490  NFFIHTPRKTYYFEDPNNAAHEWVTKINELLVANYGEMF 528


>gb|PKC07109.1| Pkinase-domain-containing protein [Rhizophagus irregularis]
 gb|PKC63720.1| Pkinase-domain-containing protein [Rhizophagus irregularis]
          Length = 424

 Score =  657 bits (1696), Expect = 0.0
 Identities = 325/355 (91%), Positives = 327/355 (92%)
 Frame = +3

Query: 3    TLGEGSYSTVVAARDRSNNREYAVXXXXXXXXXXXXXXXYVNIEKNTLNKMNHPGIVRLY 182
            TLGEGSYSTVVAARDRSNNREYAV               YVNIEKNTLNKMNHPGIVRLY
Sbjct: 70   TLGEGSYSTVVAARDRSNNREYAVKILDKKHIIKEKKVKYVNIEKNTLNKMNHPGIVRLY 129

Query: 183  YTFQDPDSLYFVLDHAKNGELLTFIKKLGSFDMDCTKFYASQILSAIEYMHSQGVIHRDL 362
            YTFQDPDSLYFVLDHAKNGELLTFIKKLGSFDMDCTKFYASQILSAIEYMHSQGVIHRDL
Sbjct: 130  YTFQDPDSLYFVLDHAKNGELLTFIKKLGSFDMDCTKFYASQILSAIEYMHSQGVIHRDL 189

Query: 363  KPENILLDEKMHVKVTDFGTAKILEQNADGEDDDRANSFVGTAEYVSPELLKEKAACKSS 542
            KPENILLDEKMHVKVTDFGTAKILEQNA+GE+DDRANSFVGTAEYVSPELLKEKAACKSS
Sbjct: 190  KPENILLDEKMHVKVTDFGTAKILEQNAEGEEDDRANSFVGTAEYVSPELLKEKAACKSS 249

Query: 543  DFWALGCIIYQLIAGRPPFKGANEYRTFQKIVNLEYSFPDGFPPVARDLVQKLLVLNPSE 722
            DFWALGCIIYQLIAGRPPFKGANEYRTFQKIVNLEYSFPDGFPPVARDLVQKLLVLNPSE
Sbjct: 250  DFWALGCIIYQLIAGRPPFKGANEYRTFQKIVNLEYSFPDGFPPVARDLVQKLLVLNPSE 309

Query: 723  RLGSGGKAGVERLKAHPFFQGIDWDTLWQQXXXXXXXXXXXXXKHNDPEFRTPTNAYLPK 902
            RLGSGGKAGVERLKAHPFFQGIDWDTLWQQ             KHNDPEFRTPTNAYLPK
Sbjct: 310  RLGSGGKAGVERLKAHPFFQGIDWDTLWQQPAPNLLPYLPPNPKHNDPEFRTPTNAYLPK 369

Query: 903  LSDNSEVNGSPIATGLRQNDPFRLESWAGGDDSSDKVDPEKVKKLEEQKRTSAQW 1067
            LSDNSEVNGSPIATGLRQNDPFRLESWAGGDDSSDKVDPEKVKKLEEQKRTSAQW
Sbjct: 370  LSDNSEVNGSPIATGLRQNDPFRLESWAGGDDSSDKVDPEKVKKLEEQKRTSAQW 424


>gb|ORY01027.1| kinase-like protein [Basidiobolus meristosporus CBS 931.73]
          Length = 514

 Score =  497 bits (1279), Expect = e-168
 Identities = 246/458 (53%), Positives = 330/458 (72%), Gaps = 4/458 (0%)
 Frame = +3

Query: 6    LGEGSYSTVVAARDRSNNREYAVXXXXXXXXXXXXXXXYVNIEKNTLNKMNHPGIVRLYY 185
            LGEGSYSTV +A + +  RE+AV               YV IEK+TL+K++HP IVRL++
Sbjct: 69   LGEGSYSTVYSAMEYNTGREFAVKVLDKRHIIKEKKVKYVTIEKSTLSKLHHPFIVRLHF 128

Query: 186  TFQDPDSLYFVLDHAKNGELLTFIKKLGSFDMDCTKFYASQILSAIEYMHSQGVIHRDLK 365
            TFQD  SLY+VLD+A+NGELL++I+KLGSFD  CT+FYA++I++A+EY+HSQG+IHRDLK
Sbjct: 129  TFQDNSSLYYVLDYAQNGELLSYIRKLGSFDEKCTRFYAAEIITAMEYIHSQGIIHRDLK 188

Query: 366  PENILLDEKMHVKVTDFGTAKILEQNADGEDDD----RANSFVGTAEYVSPELLKEKAAC 533
            PENILLD KMH+K+TDFGTAK+++   +   D+    RA+SFVGTAEYVSPELL +K   
Sbjct: 189  PENILLDHKMHIKLTDFGTAKMVDDPPEAASDELMEGRASSFVGTAEYVSPELLTDKEVS 248

Query: 534  KSSDFWALGCIIYQLIAGRPPFKGANEYRTFQKIVNLEYSFPDGFPPVARDLVQKLLVLN 713
            KS+DFWALGCI+YQL+AGRPPFKGANEY+TFQKI+ LEYSFP GFP  A+DLV++LLV +
Sbjct: 249  KSADFWALGCILYQLLAGRPPFKGANEYQTFQKIIKLEYSFPVGFPKTAQDLVERLLVAD 308

Query: 714  PSERLGSGGKAGVERLKAHPFFQGIDWDTLWQQXXXXXXXXXXXXXKHNDPEFRTPTNAY 893
            P +RLG     G+++LK HPFF+GIDW+ L +Q             +HN  E R      
Sbjct: 309  PQQRLGCDSD-GIQKLKKHPFFEGIDWNDLHKQEAPKLVPYLPPNPEHNAEELR------ 361

Query: 894  LPKLSDNSEVNGSPIATGLRQNDPFRLESWAGGDDSSDKVDPEKVKKLEEQKRTSAQWIP 1073
                S   +    P    L + DPF+ E  A  D ++   DP++ +KLE Q++  ++W P
Sbjct: 362  ----STEPDYTHPPTQPSLTEQDPFQ-EPRASIDQAN---DPDRAQKLEAQRK--SKWSP 411

Query: 1074 FILKSELIIKTGPINKRKGFFSKKRTLILTDFPRLIYVDQEKNSQKGEIYWSSRMVVELK 1253
            F+L+SELI++ G + KR+G FSKKR L+LTDFPRLIY+++EK +Q GEI WS R++ E K
Sbjct: 412  FLLESELIVRCGKLTKRRGLFSKKRVLLLTDFPRLIYINEEKMTQAGEIAWSKRLLPEYK 471

Query: 1254 NKRNFFIHTPRKTYYFEDPNNAAHEWVTKINELLVANY 1367
            NK++FF+HTP KT+YFEDP   A +WV  I++L+  +Y
Sbjct: 472  NKKHFFVHTPNKTHYFEDPTGNAQQWVESISQLMKQSY 509


>ref|XP_004346099.1| PkB kinase [Capsaspora owczarzaki ATCC 30864]
 gb|KJE94855.1| AGC/PDK1 protein kinase [Capsaspora owczarzaki ATCC 30864]
          Length = 602

 Score =  453 bits (1165), Expect = e-150
 Identities = 238/453 (52%), Positives = 304/453 (67%), Gaps = 3/453 (0%)
 Frame = +3

Query: 6    LGEGSYSTVVAARDRSNNREYAVXXXXXXXXXXXXXXXYVNIEKNTLNKMNHPGIVRLYY 185
            LGEGSYSTVV A+++S +R +AV               YVN EK+ LN++NHP  VRL+Y
Sbjct: 154  LGEGSYSTVVLAKEKSTSRYFAVKILEKKHIIKEKKVKYVNTEKDVLNRVNHPFFVRLFY 213

Query: 186  TFQDPDSLYFVLDHAKNGELLTFIKKLGSFDMDCTKFYASQILSAIEYMHSQGVIHRDLK 365
            TFQD + LYFV+  A NGELLT IKKLGSFD  C +FYA++I+ A+EY+H+ GVIHRDLK
Sbjct: 214  TFQDVERLYFVISFAANGELLTTIKKLGSFDERCAQFYAAEIVVALEYLHNLGVIHRDLK 273

Query: 366  PENILLDEKMHVKVTDFGTAKILEQNADGEDDDRANSFVGTAEYVSPELLKEKAACKSSD 545
            PENILLD  MH+K+TDFG+A ++ Q  D E D RANSFVGTAEYVSPELL EK A K+SD
Sbjct: 274  PENILLDTDMHIKITDFGSAYLIGQ--DAETDVRANSFVGTAEYVSPELLTEKIASKASD 331

Query: 546  FWALGCIIYQLIAGRPPFKGANEYRTFQKIVNLEYSFPDGFPPVARDLVQKLLVLNPSER 725
            +WALGCIIYQ++AGRPPF+  NEY+TFQKI  L+YS P+GFPP ARDLV+KLLVL+ S+R
Sbjct: 332  WWALGCIIYQMLAGRPPFRAGNEYQTFQKITKLDYSIPNGFPPAARDLVEKLLVLDSSKR 391

Query: 726  LGSGGKAGVERLKAHPFFQGIDWDTLWQQXXXXXXXXXXXXXKHNDPEFRTPTNAYLPKL 905
            LGS    GV  +K+HPFF+G++W++L  Q                 P    P   YLP +
Sbjct: 392  LGSDSAGGVNAIKSHPFFRGLEWNSLHMQ----------------QPPALVP---YLPPI 432

Query: 906  SDNSEVNGSPIATGLRQNDPFRLESWAGGDDSSDKVDPEKV---KKLEEQKRTSAQWIPF 1076
            S NS     P+ + +R +D           +S     PE+     +L  ++   +QW  F
Sbjct: 433  SRNS----VPLHSVIRDDDDEEAAPLQSALESFTLTAPERAGMRSQLLLRQAQESQWHRF 488

Query: 1077 ILKSELIIKTGPINKRKGFFSKKRTLILTDFPRLIYVDQEKNSQKGEIYWSSRMVVELKN 1256
            +   ELIIKTG I+KRKG FSK+R L+LTD PR +Y+D +K   KGEI WS+ M  E+KN
Sbjct: 489  VQVDELIIKTGIIHKRKGLFSKRRQLVLTDKPRCLYIDVDKMEIKGEIPWSTEMRFEVKN 548

Query: 1257 KRNFFIHTPRKTYYFEDPNNAAHEWVTKINELL 1355
            K+ FFIHTP +TYY ED +  A+ W  + N LL
Sbjct: 549  KKTFFIHTPNRTYYLEDLSADAYGWCEQFNALL 581


>ref|XP_021089426.1| 3-phosphoinositide-dependent protein kinase 1 isoform X1
            [Mesocricetus auratus]
          Length = 532

 Score =  421 bits (1082), Expect = e-138
 Identities = 221/464 (47%), Positives = 300/464 (64%), Gaps = 10/464 (2%)
 Frame = +3

Query: 6    LGEGSYSTVVAARDRSNNREYAVXXXXXXXXXXXXXXXYVNIEKNTLNKMNHPGIVRLYY 185
            LGEGS+STVV AR+ + +REYA+               YV  E++ +++++HP  V+LY+
Sbjct: 64   LGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSRLDHPFFVKLYF 123

Query: 186  TFQDPDSLYFVLDHAKNGELLTFIKKLGSFDMDCTKFYASQILSAIEYMHSQGVIHRDLK 365
            TFQD + LYF L +AKNGELL +I+K+GSFD  CT+FY ++I+SA+EY+H +G+IHRDLK
Sbjct: 124  TFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSALEYLHGKGIIHRDLK 183

Query: 366  PENILLDEKMHVKVTDFGTAKILEQNADGEDDDRANSFVGTAEYVSPELLKEKAACKSSD 545
            PENILL+E MH+++TDFGTAK+L   +      RANSFVGTA+YVSPELL EK+ACKSSD
Sbjct: 184  PENILLNEDMHIQITDFGTAKVLSPES---KQARANSFVGTAQYVSPELLTEKSACKSSD 240

Query: 546  FWALGCIIYQLIAGRPPFKGANEYRTFQKIVNLEYSFPDGFPPVARDLVQKLLVLNPSER 725
             WALGCIIYQL+AG PPF+  NEY  FQKI+ LEY FP+ F P ARDLV+KLLVL+ ++R
Sbjct: 241  LWALGCIIYQLVAGLPPFRAGNEYLIFQKIIKLEYDFPEKFFPKARDLVEKLLVLDATKR 300

Query: 726  LGSGGKAGVERLKAHPFFQGIDWDTLWQQXXXXXXXXXXXXXKHNDPEFRTPTN-----A 890
            LG     G E LKAHPFF+ I W+ L QQ             + ++  +    N      
Sbjct: 301  LGCEEMEGYEPLKAHPFFESITWENLHQQTPPKLTAYLPAMSEDDEDCYGNYDNLLSQFG 360

Query: 891  YLPKLSDNSEVNGSPIATGLRQNDPFRLESWAGG-DDSSDKVD---PEKVKKLEEQKRTS 1058
             +   S +S  + S + T L Q     +E +    D +S ++D    E  K+L  +K+ S
Sbjct: 361  CMQVSSSSSSHSLSAVDTSLPQRSGSNIEQYIHDLDTNSFELDLQFSEDEKRLLLEKQAS 420

Query: 1059 AQ-WIPFILKSELIIKTGPINKRKGFFSKKRTLILTDFPRLIYVDQEKNSQKGEIYWSSR 1235
               W  F+ ++ LI+K GP++KRKG F+++R L+LT+ P L YVD      KGEI WS  
Sbjct: 421  GNPWHQFV-ENNLILKMGPVDKRKGLFARRRQLLLTEGPHLYYVDPVNKVLKGEIPWSQE 479

Query: 1236 MVVELKNKRNFFIHTPRKTYYFEDPNNAAHEWVTKINELLVANY 1367
            +  E KN + FF+HTP +TYY  DP+  AH+W  KI E+    Y
Sbjct: 480  LRPEAKNFKTFFVHTPNRTYYLMDPSGNAHKWCRKIQEVWRQRY 523


>ref|XP_006979015.1| PREDICTED: 3-phosphoinositide-dependent protein kinase 1 [Peromyscus
            maniculatus bairdii]
 ref|XP_016834747.1| PREDICTED: 3-phosphoinositide-dependent protein kinase 1 [Cricetulus
            griseus]
          Length = 532

 Score =  421 bits (1082), Expect = e-138
 Identities = 221/464 (47%), Positives = 300/464 (64%), Gaps = 10/464 (2%)
 Frame = +3

Query: 6    LGEGSYSTVVAARDRSNNREYAVXXXXXXXXXXXXXXXYVNIEKNTLNKMNHPGIVRLYY 185
            LGEGS+STVV AR+ + +REYA+               YV  E++ +++++HP  V+LY+
Sbjct: 64   LGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSRLDHPFFVKLYF 123

Query: 186  TFQDPDSLYFVLDHAKNGELLTFIKKLGSFDMDCTKFYASQILSAIEYMHSQGVIHRDLK 365
            TFQD + LYF L +AKNGELL +I+K+GSFD  CT+FY ++I+SA+EY+H +G+IHRDLK
Sbjct: 124  TFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSALEYLHGKGIIHRDLK 183

Query: 366  PENILLDEKMHVKVTDFGTAKILEQNADGEDDDRANSFVGTAEYVSPELLKEKAACKSSD 545
            PENILL+E MH+++TDFGTAK+L   +      RANSFVGTA+YVSPELL EK+ACKSSD
Sbjct: 184  PENILLNEDMHIQITDFGTAKVLSPES---KQARANSFVGTAQYVSPELLTEKSACKSSD 240

Query: 546  FWALGCIIYQLIAGRPPFKGANEYRTFQKIVNLEYSFPDGFPPVARDLVQKLLVLNPSER 725
             WALGCIIYQL+AG PPF+  NEY  FQKI+ LEY FP+ F P ARDLV+KLLVL+ ++R
Sbjct: 241  LWALGCIIYQLVAGLPPFRAGNEYLIFQKIIKLEYDFPEKFFPKARDLVEKLLVLDATKR 300

Query: 726  LGSGGKAGVERLKAHPFFQGIDWDTLWQQXXXXXXXXXXXXXKHNDPEFRTPTN-----A 890
            LG     G E LKAHPFF+ I W+ L QQ             + ++  +    N      
Sbjct: 301  LGCEEMEGYEPLKAHPFFESITWENLHQQTPPKLTAYLPAMSEDDEDCYGNYDNLLSQFG 360

Query: 891  YLPKLSDNSEVNGSPIATGLRQNDPFRLESWAGG-DDSSDKVD---PEKVKKLEEQKRTS 1058
             +   S +S  + S + T L Q     +E +    D +S ++D    E  K+L  +K+ S
Sbjct: 361  CMQVSSSSSSHSLSAVDTSLPQRSGSNIEQYIHDLDTNSFELDLQFSEDEKRLLLEKQAS 420

Query: 1059 AQ-WIPFILKSELIIKTGPINKRKGFFSKKRTLILTDFPRLIYVDQEKNSQKGEIYWSSR 1235
               W  F+ ++ LI+K GP++KRKG F+++R L+LT+ P L YVD      KGEI WS  
Sbjct: 421  GNPWHQFV-ENNLILKMGPVDKRKGLFARRRQLLLTEGPHLYYVDPVNKVLKGEIPWSQE 479

Query: 1236 MVVELKNKRNFFIHTPRKTYYFEDPNNAAHEWVTKINELLVANY 1367
            +  E KN + FF+HTP +TYY  DP+  AH+W  KI E+    Y
Sbjct: 480  LRPEAKNFKTFFVHTPNRTYYLMDPSGNAHKWCRKIQEVWRQRY 523


>ref|XP_006913986.1| PREDICTED: 3-phosphoinositide-dependent protein kinase 1 [Pteropus
            alecto]
 ref|XP_011374914.1| 3-phosphoinositide-dependent protein kinase 1 [Pteropus vampyrus]
          Length = 557

 Score =  422 bits (1084), Expect = e-138
 Identities = 219/458 (47%), Positives = 299/458 (65%), Gaps = 9/458 (1%)
 Frame = +3

Query: 6    LGEGSYSTVVAARDRSNNREYAVXXXXXXXXXXXXXXXYVNIEKNTLNKMNHPGIVRLYY 185
            LGEGS+STVV AR+ + +REYA+               YV  E++ +++++HP  V+LY+
Sbjct: 90   LGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSRLDHPFFVKLYF 149

Query: 186  TFQDPDSLYFVLDHAKNGELLTFIKKLGSFDMDCTKFYASQILSAIEYMHSQGVIHRDLK 365
            TFQD + LYF L +AKNGELL +I+K+GSFD  CT+FY ++++SA+EY+H +G+IHRDLK
Sbjct: 150  TFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEMVSALEYLHGRGIIHRDLK 209

Query: 366  PENILLDEKMHVKVTDFGTAKILEQNADGEDDDRANSFVGTAEYVSPELLKEKAACKSSD 545
            PENILL+E MH+++TDFGTAK+L   +      RANSFVGTA+YVSPELL EK+ACKSSD
Sbjct: 210  PENILLNEDMHIQITDFGTAKVLSPES---KQARANSFVGTAQYVSPELLTEKSACKSSD 266

Query: 546  FWALGCIIYQLIAGRPPFKGANEYRTFQKIVNLEYSFPDGFPPVARDLVQKLLVLNPSER 725
             WALGCIIYQL+AG PPF+  NEY  FQKI+ LEY FP+ F P ARDLV+KLLVL+ ++R
Sbjct: 267  LWALGCIIYQLVAGLPPFRAGNEYLIFQKIIKLEYDFPEKFFPKARDLVEKLLVLDATKR 326

Query: 726  LGSGGKAGVERLKAHPFFQGIDWDTLWQQXXXXXXXXXXXXXKHNDPEFRTPTNAY---- 893
            LG     G   LKAHPFF+ I W+ L  Q             + ++  +    N      
Sbjct: 327  LGCEEMEGYGPLKAHPFFESITWENLHHQTPPKLTAYLPAMSEDDEDCYGNYDNLLSQFG 386

Query: 894  LPKLSDNSEVNGSPIATGLRQNDPFRLESWAGGDDSS----DKVDPEKVKKLEEQKRTSA 1061
              ++S +S  + S + TGL Q     +E +  G D++    D +  E  KKL  +K+ S 
Sbjct: 387  CMQVSSSSSHSLSALDTGLPQRAGSNIEQYIHGLDTNSFELDLLFSEDEKKLLLEKQASG 446

Query: 1062 Q-WIPFILKSELIIKTGPINKRKGFFSKKRTLILTDFPRLIYVDQEKNSQKGEIYWSSRM 1238
              W  F+ ++ LI+K GP++KRKG F+++R L+LT+ P L YVD      KGEI WS  +
Sbjct: 447  NPWHQFV-ENNLILKMGPVDKRKGLFARRRQLLLTEGPHLYYVDPVNKVLKGEIPWSQEL 505

Query: 1239 VVELKNKRNFFIHTPRKTYYFEDPNNAAHEWVTKINEL 1352
              E KN + FF+HTP +TYY  DP+  AH+W  KI E+
Sbjct: 506  RPEAKNFKTFFVHTPNRTYYLMDPSGNAHKWCKKIQEV 543


>gb|ELK10765.1| 3-phosphoinositide-dependent protein kinase 1 [Pteropus alecto]
          Length = 563

 Score =  422 bits (1084), Expect = e-138
 Identities = 219/458 (47%), Positives = 299/458 (65%), Gaps = 9/458 (1%)
 Frame = +3

Query: 6    LGEGSYSTVVAARDRSNNREYAVXXXXXXXXXXXXXXXYVNIEKNTLNKMNHPGIVRLYY 185
            LGEGS+STVV AR+ + +REYA+               YV  E++ +++++HP  V+LY+
Sbjct: 96   LGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSRLDHPFFVKLYF 155

Query: 186  TFQDPDSLYFVLDHAKNGELLTFIKKLGSFDMDCTKFYASQILSAIEYMHSQGVIHRDLK 365
            TFQD + LYF L +AKNGELL +I+K+GSFD  CT+FY ++++SA+EY+H +G+IHRDLK
Sbjct: 156  TFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEMVSALEYLHGRGIIHRDLK 215

Query: 366  PENILLDEKMHVKVTDFGTAKILEQNADGEDDDRANSFVGTAEYVSPELLKEKAACKSSD 545
            PENILL+E MH+++TDFGTAK+L   +      RANSFVGTA+YVSPELL EK+ACKSSD
Sbjct: 216  PENILLNEDMHIQITDFGTAKVLSPES---KQARANSFVGTAQYVSPELLTEKSACKSSD 272

Query: 546  FWALGCIIYQLIAGRPPFKGANEYRTFQKIVNLEYSFPDGFPPVARDLVQKLLVLNPSER 725
             WALGCIIYQL+AG PPF+  NEY  FQKI+ LEY FP+ F P ARDLV+KLLVL+ ++R
Sbjct: 273  LWALGCIIYQLVAGLPPFRAGNEYLIFQKIIKLEYDFPEKFFPKARDLVEKLLVLDATKR 332

Query: 726  LGSGGKAGVERLKAHPFFQGIDWDTLWQQXXXXXXXXXXXXXKHNDPEFRTPTNAY---- 893
            LG     G   LKAHPFF+ I W+ L  Q             + ++  +    N      
Sbjct: 333  LGCEEMEGYGPLKAHPFFESITWENLHHQTPPKLTAYLPAMSEDDEDCYGNYDNLLSQFG 392

Query: 894  LPKLSDNSEVNGSPIATGLRQNDPFRLESWAGGDDSS----DKVDPEKVKKLEEQKRTSA 1061
              ++S +S  + S + TGL Q     +E +  G D++    D +  E  KKL  +K+ S 
Sbjct: 393  CMQVSSSSSHSLSALDTGLPQRAGSNIEQYIHGLDTNSFELDLLFSEDEKKLLLEKQASG 452

Query: 1062 Q-WIPFILKSELIIKTGPINKRKGFFSKKRTLILTDFPRLIYVDQEKNSQKGEIYWSSRM 1238
              W  F+ ++ LI+K GP++KRKG F+++R L+LT+ P L YVD      KGEI WS  +
Sbjct: 453  NPWHQFV-ENNLILKMGPVDKRKGLFARRRQLLLTEGPHLYYVDPVNKVLKGEIPWSQEL 511

Query: 1239 VVELKNKRNFFIHTPRKTYYFEDPNNAAHEWVTKINEL 1352
              E KN + FF+HTP +TYY  DP+  AH+W  KI E+
Sbjct: 512  RPEAKNFKTFFVHTPNRTYYLMDPSGNAHKWCKKIQEV 549


>ref|XP_007606614.1| PREDICTED: 3-phosphoinositide-dependent protein kinase 1 [Cricetulus
            griseus]
          Length = 532

 Score =  421 bits (1081), Expect = e-138
 Identities = 221/464 (47%), Positives = 300/464 (64%), Gaps = 10/464 (2%)
 Frame = +3

Query: 6    LGEGSYSTVVAARDRSNNREYAVXXXXXXXXXXXXXXXYVNIEKNTLNKMNHPGIVRLYY 185
            LGEGS+STVV AR+ + +REYA+               YV  E++ +++++HP  V+LY+
Sbjct: 64   LGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSRLDHPFFVKLYF 123

Query: 186  TFQDPDSLYFVLDHAKNGELLTFIKKLGSFDMDCTKFYASQILSAIEYMHSQGVIHRDLK 365
            TFQD + LYF L +AKNGELL +I+K+GSFD  CT+FY ++I+SA+EY+H +G+IHRDLK
Sbjct: 124  TFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSALEYLHGKGIIHRDLK 183

Query: 366  PENILLDEKMHVKVTDFGTAKILEQNADGEDDDRANSFVGTAEYVSPELLKEKAACKSSD 545
            PENILL+E MH+++TDFGTAK+L   +      RANSFVGTA+YVSPELL EK+ACKSSD
Sbjct: 184  PENILLNEDMHIQITDFGTAKVLSPES---KQARANSFVGTAQYVSPELLTEKSACKSSD 240

Query: 546  FWALGCIIYQLIAGRPPFKGANEYRTFQKIVNLEYSFPDGFPPVARDLVQKLLVLNPSER 725
             WALGCIIYQL+AG PPF+  NEY  FQKI+ LEY FP+ F P ARDLV+KLLVL+ ++R
Sbjct: 241  LWALGCIIYQLVAGLPPFRAGNEYLIFQKIIKLEYDFPEKFFPKARDLVEKLLVLDATKR 300

Query: 726  LGSGGKAGVERLKAHPFFQGIDWDTLWQQXXXXXXXXXXXXXKHNDPEFRTPTN-----A 890
            LG     G E LKAHPFF+ I W+ L QQ             + ++  +    N      
Sbjct: 301  LGCEEMEGYEPLKAHPFFESITWENLHQQTPPKLTAYLPAMSEDDEDCYGNYDNLLSQFG 360

Query: 891  YLPKLSDNSEVNGSPIATGLRQNDPFRLESWAGG-DDSSDKVD---PEKVKKLEEQKRTS 1058
             +   S +S  + S + T L Q     +E +    D +S ++D    E  K+L  +K+ S
Sbjct: 361  CMQVSSSSSSHSLSAVDTSLPQRSGSNIEQYIHDLDTNSFELDLQFSEDEKRLLLEKQAS 420

Query: 1059 AQ-WIPFILKSELIIKTGPINKRKGFFSKKRTLILTDFPRLIYVDQEKNSQKGEIYWSSR 1235
               W  F+ ++ LI+K GP++KRKG F+++R L+LT+ P L YVD      KGEI WS  
Sbjct: 421  GNPWHQFV-ENNLILKMGPVDKRKGLFARRRQLLLTEGPHLYYVDPVNKVLKGEIPWSHE 479

Query: 1236 MVVELKNKRNFFIHTPRKTYYFEDPNNAAHEWVTKINELLVANY 1367
            +  E KN + FF+HTP +TYY  DP+  AH+W  KI E+    Y
Sbjct: 480  LRPEAKNFKTFFVHTPNRTYYLMDPSGNAHKWCRKIQEVWRQRY 523


>ref|XP_008061434.1| 3-phosphoinositide-dependent protein kinase 1 [Carlito syrichta]
 ref|XP_021570796.1| 3-phosphoinositide-dependent protein kinase 1 [Carlito syrichta]
          Length = 531

 Score =  420 bits (1080), Expect = e-138
 Identities = 221/464 (47%), Positives = 299/464 (64%), Gaps = 10/464 (2%)
 Frame = +3

Query: 6    LGEGSYSTVVAARDRSNNREYAVXXXXXXXXXXXXXXXYVNIEKNTLNKMNHPGIVRLYY 185
            LGEGS+STVV AR+ + +REYA+               YV  E++ +++++HP  V+LY+
Sbjct: 63   LGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSRLDHPFFVKLYF 122

Query: 186  TFQDPDSLYFVLDHAKNGELLTFIKKLGSFDMDCTKFYASQILSAIEYMHSQGVIHRDLK 365
            TFQD + LYF L +AKNGELL +I+K+GSFD  CT+FY ++I+SA+EY+H +G+IHRDLK
Sbjct: 123  TFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSALEYLHGKGIIHRDLK 182

Query: 366  PENILLDEKMHVKVTDFGTAKILEQNADGEDDDRANSFVGTAEYVSPELLKEKAACKSSD 545
            PENILL+E MH+++TDFGTAK+L   +      RANSFVGTA+YVSPELL EK+ACKSSD
Sbjct: 183  PENILLNEDMHIQITDFGTAKVLSPES---KQARANSFVGTAQYVSPELLTEKSACKSSD 239

Query: 546  FWALGCIIYQLIAGRPPFKGANEYRTFQKIVNLEYSFPDGFPPVARDLVQKLLVLNPSER 725
             WALGCIIYQL+AG PPF+  NEY  FQKI+ LEY FP+ F P ARDLV+KLLVL+ ++R
Sbjct: 240  LWALGCIIYQLVAGLPPFRAGNEYLIFQKIIKLEYDFPEKFFPKARDLVEKLLVLDATKR 299

Query: 726  LGSGGKAGVERLKAHPFFQGIDWDTLWQQXXXXXXXXXXXXXKHNDPEFRTPTN-----A 890
            LG     G E LKAHPFF+ I W+ L QQ             + ++  +    N      
Sbjct: 300  LGCEEMEGYEPLKAHPFFESITWENLHQQTPPKLTAYLPAMSEDDEDCYGNYDNLLSQFG 359

Query: 891  YLPKLSDNSEVNGSPIATGLRQNDPFRLESWAGG-DDSSDKVD---PEKVKKLEEQKRTS 1058
             +   S +S  + S   TGL Q     +E +    D +S ++D    E  K+L  +K+  
Sbjct: 360  CMQVSSSSSSHSFSASDTGLPQRSGSNIEQYIHDLDTNSFELDLQFSEDEKRLLLEKQAG 419

Query: 1059 AQ-WIPFILKSELIIKTGPINKRKGFFSKKRTLILTDFPRLIYVDQEKNSQKGEIYWSSR 1235
               W  F+ ++ LI+K GP++KRKG F+++R L+LT+ P L YVD      KGEI WS  
Sbjct: 420  GNPWHQFV-ENNLILKMGPVDKRKGLFARRRQLLLTEGPHLYYVDPVNKVLKGEIPWSQE 478

Query: 1236 MVVELKNKRNFFIHTPRKTYYFEDPNNAAHEWVTKINELLVANY 1367
            +  E KN + FF+HTP +TYY  DP+  AH+W  KI E+    Y
Sbjct: 479  LRPEAKNFKTFFVHTPNRTYYLMDPSGNAHKWCRKIQEVWRQRY 522


>ref|XP_005081691.1| 3-phosphoinositide-dependent protein kinase 1 isoform X2
            [Mesocricetus auratus]
          Length = 559

 Score =  421 bits (1082), Expect = e-138
 Identities = 221/464 (47%), Positives = 300/464 (64%), Gaps = 10/464 (2%)
 Frame = +3

Query: 6    LGEGSYSTVVAARDRSNNREYAVXXXXXXXXXXXXXXXYVNIEKNTLNKMNHPGIVRLYY 185
            LGEGS+STVV AR+ + +REYA+               YV  E++ +++++HP  V+LY+
Sbjct: 91   LGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSRLDHPFFVKLYF 150

Query: 186  TFQDPDSLYFVLDHAKNGELLTFIKKLGSFDMDCTKFYASQILSAIEYMHSQGVIHRDLK 365
            TFQD + LYF L +AKNGELL +I+K+GSFD  CT+FY ++I+SA+EY+H +G+IHRDLK
Sbjct: 151  TFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSALEYLHGKGIIHRDLK 210

Query: 366  PENILLDEKMHVKVTDFGTAKILEQNADGEDDDRANSFVGTAEYVSPELLKEKAACKSSD 545
            PENILL+E MH+++TDFGTAK+L   +      RANSFVGTA+YVSPELL EK+ACKSSD
Sbjct: 211  PENILLNEDMHIQITDFGTAKVLSPES---KQARANSFVGTAQYVSPELLTEKSACKSSD 267

Query: 546  FWALGCIIYQLIAGRPPFKGANEYRTFQKIVNLEYSFPDGFPPVARDLVQKLLVLNPSER 725
             WALGCIIYQL+AG PPF+  NEY  FQKI+ LEY FP+ F P ARDLV+KLLVL+ ++R
Sbjct: 268  LWALGCIIYQLVAGLPPFRAGNEYLIFQKIIKLEYDFPEKFFPKARDLVEKLLVLDATKR 327

Query: 726  LGSGGKAGVERLKAHPFFQGIDWDTLWQQXXXXXXXXXXXXXKHNDPEFRTPTN-----A 890
            LG     G E LKAHPFF+ I W+ L QQ             + ++  +    N      
Sbjct: 328  LGCEEMEGYEPLKAHPFFESITWENLHQQTPPKLTAYLPAMSEDDEDCYGNYDNLLSQFG 387

Query: 891  YLPKLSDNSEVNGSPIATGLRQNDPFRLESWAGG-DDSSDKVD---PEKVKKLEEQKRTS 1058
             +   S +S  + S + T L Q     +E +    D +S ++D    E  K+L  +K+ S
Sbjct: 388  CMQVSSSSSSHSLSAVDTSLPQRSGSNIEQYIHDLDTNSFELDLQFSEDEKRLLLEKQAS 447

Query: 1059 AQ-WIPFILKSELIIKTGPINKRKGFFSKKRTLILTDFPRLIYVDQEKNSQKGEIYWSSR 1235
               W  F+ ++ LI+K GP++KRKG F+++R L+LT+ P L YVD      KGEI WS  
Sbjct: 448  GNPWHQFV-ENNLILKMGPVDKRKGLFARRRQLLLTEGPHLYYVDPVNKVLKGEIPWSQE 506

Query: 1236 MVVELKNKRNFFIHTPRKTYYFEDPNNAAHEWVTKINELLVANY 1367
            +  E KN + FF+HTP +TYY  DP+  AH+W  KI E+    Y
Sbjct: 507  LRPEAKNFKTFFVHTPNRTYYLMDPSGNAHKWCRKIQEVWRQRY 550


>ref|XP_020024613.1| 3-phosphoinositide-dependent protein kinase 1 isoform X2 [Castor
            canadensis]
          Length = 532

 Score =  419 bits (1077), Expect = e-138
 Identities = 220/464 (47%), Positives = 299/464 (64%), Gaps = 10/464 (2%)
 Frame = +3

Query: 6    LGEGSYSTVVAARDRSNNREYAVXXXXXXXXXXXXXXXYVNIEKNTLNKMNHPGIVRLYY 185
            LGEGS+STVV AR+ + +REYA+               YV  E++ +++++HP  V+LY+
Sbjct: 63   LGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSRLDHPFFVKLYF 122

Query: 186  TFQDPDSLYFVLDHAKNGELLTFIKKLGSFDMDCTKFYASQILSAIEYMHSQGVIHRDLK 365
            TFQD + LYF L +AKNGELL +I+K+GSFD  CT+FY ++I+SA+EY+H +G+IHRDLK
Sbjct: 123  TFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSALEYLHGKGIIHRDLK 182

Query: 366  PENILLDEKMHVKVTDFGTAKILEQNADGEDDDRANSFVGTAEYVSPELLKEKAACKSSD 545
            PENILL+E MH+++TDFGTAK+L   +      RANSFVGTA+YVSPELL EK+ACKSSD
Sbjct: 183  PENILLNEDMHIQITDFGTAKVLSPES---KQARANSFVGTAQYVSPELLTEKSACKSSD 239

Query: 546  FWALGCIIYQLIAGRPPFKGANEYRTFQKIVNLEYSFPDGFPPVARDLVQKLLVLNPSER 725
             WALGCIIYQL+AG PPF+  NEY  FQKI+ LEY FP+ F P ARDLV+KLLVL+ ++R
Sbjct: 240  LWALGCIIYQLVAGLPPFRAGNEYLIFQKIIKLEYDFPEKFFPKARDLVEKLLVLDATKR 299

Query: 726  LGSGGKAGVERLKAHPFFQGIDWDTLWQQXXXXXXXXXXXXXKHNDPEFRTPTN-----A 890
            LG     G E LKAHPFF+ I W+ L QQ             + ++  +    N      
Sbjct: 300  LGCEEMEGYEPLKAHPFFESIMWENLHQQTPPKLTAYLPAMSEDDEDCYGNYDNLLSQFG 359

Query: 891  YLPKLSDNSEVNGSPIATGLRQNDPFRLESWAGG-DDSSDKVD---PEKVKKLEEQKRTS 1058
             +   S +S  + S + TGL       +E +    D +S ++D    E  K+L  +K+  
Sbjct: 360  CMQVSSSSSSHSLSAVDTGLPHRSGSNIEQYIHDLDTNSFELDLQFSEDEKRLLLEKQAG 419

Query: 1059 AQ-WIPFILKSELIIKTGPINKRKGFFSKKRTLILTDFPRLIYVDQEKNSQKGEIYWSSR 1235
               W  F+ ++ LI+K GP++KRKG F+++R L+LT+ P L YVD      KGEI WS  
Sbjct: 420  GNPWHQFV-ENNLILKMGPVDKRKGLFARRRQLLLTEGPHLYYVDPVNKVLKGEIPWSQE 478

Query: 1236 MVVELKNKRNFFIHTPRKTYYFEDPNNAAHEWVTKINELLVANY 1367
            +  E KN + FF+HTP +TYY  DP+  AH+W  KI E+    Y
Sbjct: 479  LRPEAKNFKTFFVHTPNRTYYLMDPSGNAHKWCRKIQEVWRQRY 522


>ref|XP_015977724.1| PREDICTED: 3-phosphoinositide-dependent protein kinase 1 isoform X3
            [Rousettus aegyptiacus]
          Length = 530

 Score =  419 bits (1076), Expect = e-137
 Identities = 219/458 (47%), Positives = 299/458 (65%), Gaps = 9/458 (1%)
 Frame = +3

Query: 6    LGEGSYSTVVAARDRSNNREYAVXXXXXXXXXXXXXXXYVNIEKNTLNKMNHPGIVRLYY 185
            LGEGS+STVV AR+ + +REYA+               YV  E++ +++++HP  V+LY+
Sbjct: 63   LGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSRLDHPFFVKLYF 122

Query: 186  TFQDPDSLYFVLDHAKNGELLTFIKKLGSFDMDCTKFYASQILSAIEYMHSQGVIHRDLK 365
            TFQD + LYF L +AKNGELL +I+K+GSFD  CT+FY ++++SA+EY+H +G+IHRDLK
Sbjct: 123  TFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEMVSALEYLHGRGIIHRDLK 182

Query: 366  PENILLDEKMHVKVTDFGTAKILEQNADGEDDDRANSFVGTAEYVSPELLKEKAACKSSD 545
            PENILL+E MH+++TDFGTAK+L   +      RANSFVGTA+YVSPELL EK+ACKSSD
Sbjct: 183  PENILLNEDMHIQITDFGTAKVLSPES---KQARANSFVGTAQYVSPELLTEKSACKSSD 239

Query: 546  FWALGCIIYQLIAGRPPFKGANEYRTFQKIVNLEYSFPDGFPPVARDLVQKLLVLNPSER 725
             WALGCIIYQL+AG PPF+  NEY  FQKI+ LEY FP+ F P ARDLV+KLLVL+ ++R
Sbjct: 240  LWALGCIIYQLVAGLPPFRAGNEYLIFQKIIKLEYDFPEKFFPKARDLVEKLLVLDATKR 299

Query: 726  LGSGGKAGVERLKAHPFFQGIDWDTLWQQXXXXXXXXXXXXXKHNDPEFRTPTNAY---- 893
            LG     G   LKAHPFF+ I W+ L  Q             + ++  +    N      
Sbjct: 300  LGCEEMGGYGPLKAHPFFESITWENLHHQTPPKLTAYLPAMSEDDEDCYGNYDNLLSQFG 359

Query: 894  LPKLSDNSEVNGSPIATGLRQNDPFRLESWAGG-DDSSDKVD---PEKVKKLEEQKRTSA 1061
              ++S +S  + S + TGL Q     +E +    D +S ++D    E  KKL  +K+ S 
Sbjct: 360  CMQVSSSSSHSLSALDTGLPQRAGSNIEQYIHDLDTNSFELDLQFSEDEKKLLLEKQASG 419

Query: 1062 Q-WIPFILKSELIIKTGPINKRKGFFSKKRTLILTDFPRLIYVDQEKNSQKGEIYWSSRM 1238
              W  F+ ++ LI+K GP++KRKG F+++R L+LT+ P L YVD      KGEI WS  +
Sbjct: 420  NPWHQFV-ENNLILKMGPVDKRKGLFARRRQLLLTEGPHLYYVDPVNKVLKGEIPWSQEL 478

Query: 1239 VVELKNKRNFFIHTPRKTYYFEDPNNAAHEWVTKINEL 1352
              E KN + FF+HTP +TYY  DP+  AH+W  KI E+
Sbjct: 479  RPEAKNFKTFFVHTPNRTYYLMDPSGNAHKWCKKIQEV 516


>ref|XP_008843764.1| PREDICTED: 3-phosphoinositide-dependent protein kinase 1 isoform X2
            [Nannospalax galili]
          Length = 531

 Score =  419 bits (1076), Expect = e-137
 Identities = 216/464 (46%), Positives = 296/464 (63%), Gaps = 10/464 (2%)
 Frame = +3

Query: 6    LGEGSYSTVVAARDRSNNREYAVXXXXXXXXXXXXXXXYVNIEKNTLNKMNHPGIVRLYY 185
            LGEGS+STVV AR+ + +REYA+               YV  E++ +++++HP  V+LY+
Sbjct: 63   LGEGSFSTVVLARELTTSREYAIKILEKRHIIKENKVPYVTRERDVMSRLDHPFFVKLYF 122

Query: 186  TFQDPDSLYFVLDHAKNGELLTFIKKLGSFDMDCTKFYASQILSAIEYMHSQGVIHRDLK 365
            TFQD + LYF L +AKNGELL +I+K+GSFD  CT+FY ++I+SA+EY+H +G+IHRDLK
Sbjct: 123  TFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSALEYLHGKGIIHRDLK 182

Query: 366  PENILLDEKMHVKVTDFGTAKILEQNADGEDDDRANSFVGTAEYVSPELLKEKAACKSSD 545
            PENILL+E MH+++TDFGTAK+L   +      RANSFVGTA+YVSPELL EK+ACKSSD
Sbjct: 183  PENILLNEDMHIQITDFGTAKVLSPES---KQARANSFVGTAQYVSPELLTEKSACKSSD 239

Query: 546  FWALGCIIYQLIAGRPPFKGANEYRTFQKIVNLEYSFPDGFPPVARDLVQKLLVLNPSER 725
             WALGCIIYQL+AG PPF+  NEY  FQKI+ LEY FP+ F P ARDLV+KLLVL+ ++R
Sbjct: 240  LWALGCIIYQLVAGLPPFRAGNEYLIFQKIIKLEYDFPEKFFPKARDLVEKLLVLDATKR 299

Query: 726  LGSGGKAGVERLKAHPFFQGIDWDTLWQQXXXXXXXXXXXXXKHNDPEFRTPTN-----A 890
            LG     G E LKAHPFF+ I W+ L QQ             + ++  +    N      
Sbjct: 300  LGCEEMEGYEPLKAHPFFESITWENLHQQTPPKLTAYLPAMSEDDEDCYGNYDNLLSQFG 359

Query: 891  YLPKLSDNSEVNGSPIATGLRQNDPFRLESWAGGDDSSD-----KVDPEKVKKLEEQKRT 1055
             +   S +S  + S +  GL       +E +    D++      +   E+ + L E++  
Sbjct: 360  CMQVSSSSSSHSLSAVDAGLPHRSGSNIEQYIHDLDTNSFELDLQFSEEEKRLLLEKQAG 419

Query: 1056 SAQWIPFILKSELIIKTGPINKRKGFFSKKRTLILTDFPRLIYVDQEKNSQKGEIYWSSR 1235
               W  F+ ++ LI+K GP++KRKG F+++R L+LT+ P L YVD      KGEI WS  
Sbjct: 420  GNPWHQFV-ENNLILKMGPVDKRKGLFARRRQLLLTEGPHLYYVDPVNKVLKGEIPWSQE 478

Query: 1236 MVVELKNKRNFFIHTPRKTYYFEDPNNAAHEWVTKINELLVANY 1367
            +  E KN + FF+HTP +TYY  DP+  AH+W  KI E+    Y
Sbjct: 479  LRPEAKNFKTFFVHTPNRTYYLMDPSGNAHKWCRKIQEVWRQRY 522


>ref|XP_014442528.1| PREDICTED: 3-phosphoinositide-dependent protein kinase 1 [Tupaia
            chinensis]
          Length = 531

 Score =  419 bits (1076), Expect = e-137
 Identities = 220/464 (47%), Positives = 301/464 (64%), Gaps = 10/464 (2%)
 Frame = +3

Query: 6    LGEGSYSTVVAARDRSNNREYAVXXXXXXXXXXXXXXXYVNIEKNTLNKMNHPGIVRLYY 185
            LGEGS+STVV AR+ + +REYA+               YV  E++ +++++HP  V+LY+
Sbjct: 63   LGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSRLDHPFFVKLYF 122

Query: 186  TFQDPDSLYFVLDHAKNGELLTFIKKLGSFDMDCTKFYASQILSAIEYMHSQGVIHRDLK 365
            TFQD + LYF L +AKNGELL +I+K+GSFD  CT+FYA++I+SA+EY+H +G+IHRDLK
Sbjct: 123  TFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYAAEIVSALEYLHGKGIIHRDLK 182

Query: 366  PENILLDEKMHVKVTDFGTAKILEQNADGEDDDRANSFVGTAEYVSPELLKEKAACKSSD 545
            PENILL+E MH+++TDFGTAK+L   +      RANSFVGTA+YVSPELL EK+ACKSSD
Sbjct: 183  PENILLNEDMHIQITDFGTAKVLSPES---KQARANSFVGTAQYVSPELLTEKSACKSSD 239

Query: 546  FWALGCIIYQLIAGRPPFKGANEYRTFQKIVNLEYSFPDGFPPVARDLVQKLLVLNPSER 725
             WALGCIIYQL+AG PPF+  NEY  FQKI+ LEY FP+ F P ARDLV++LLVL+ ++R
Sbjct: 240  LWALGCIIYQLVAGLPPFRAGNEYLIFQKIIKLEYDFPEKFFPKARDLVERLLVLDAAKR 299

Query: 726  LGSGGKAGVERLKAHPFFQGIDWDTLWQQXXXXXXXXXXXXXKHNDPEFRTPTN-----A 890
            LG     G   L+AH FF+ I W+ L QQ             + ++  +    N      
Sbjct: 300  LGCEEMEGYGPLRAHSFFESITWENLHQQTPPKLTAYLPAMSEDDEDCYGNYDNLLSQFG 359

Query: 891  YLPKLSDNSEVNGSPIATGLRQNDPFRLESWAGG-DDSSDKVD---PEKVKKLEEQKRTS 1058
             +   + +S  + S + TGL Q     +E +  G D +S ++D    E  KKL  +K+ S
Sbjct: 360  CMQVSASSSSHSLSALDTGLPQRSGSNIEQYIHGLDTNSFELDLQFSEDEKKLLLEKQAS 419

Query: 1059 AQ-WIPFILKSELIIKTGPINKRKGFFSKKRTLILTDFPRLIYVDQEKNSQKGEIYWSSR 1235
               W  F+ ++ LI+K GP++KRKG F+++R L+LT+ P L YVD      KGEI WS  
Sbjct: 420  ENPWHQFV-ENNLILKMGPVDKRKGLFARRRQLLLTEGPHLYYVDPVNKVLKGEIPWSQE 478

Query: 1236 MVVELKNKRNFFIHTPRKTYYFEDPNNAAHEWVTKINELLVANY 1367
            +  E KN + FF+HTP +TYY  DP+  AH+W  KI E+    Y
Sbjct: 479  LRPEAKNFKTFFVHTPNRTYYLMDPSGNAHKWCRKIQEVWRQRY 522


>ref|XP_005349254.1| PREDICTED: 3-phosphoinositide-dependent protein kinase 1 [Microtus
            ochrogaster]
          Length = 559

 Score =  419 bits (1078), Expect = e-137
 Identities = 220/464 (47%), Positives = 299/464 (64%), Gaps = 10/464 (2%)
 Frame = +3

Query: 6    LGEGSYSTVVAARDRSNNREYAVXXXXXXXXXXXXXXXYVNIEKNTLNKMNHPGIVRLYY 185
            LGEGS+STVV AR+ + +REYA+               YV  E++ +++++HP  V+LY+
Sbjct: 91   LGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSRLDHPFFVKLYF 150

Query: 186  TFQDPDSLYFVLDHAKNGELLTFIKKLGSFDMDCTKFYASQILSAIEYMHSQGVIHRDLK 365
            TFQD + LYF L +AKNGELL +I+K+GSFD  CT+FY ++I+SA+EY+H +G+IHRDLK
Sbjct: 151  TFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSALEYLHGKGIIHRDLK 210

Query: 366  PENILLDEKMHVKVTDFGTAKILEQNADGEDDDRANSFVGTAEYVSPELLKEKAACKSSD 545
            PENILL+E MH+++TDFGTAK+L   +      RANSFVGTA+YVSPELL EK+ACKSSD
Sbjct: 211  PENILLNEDMHIQITDFGTAKVLSPES---KQARANSFVGTAQYVSPELLTEKSACKSSD 267

Query: 546  FWALGCIIYQLIAGRPPFKGANEYRTFQKIVNLEYSFPDGFPPVARDLVQKLLVLNPSER 725
             WALGCIIYQL+AG PPF+  NEY  FQKI+ LEY FP+ F P ARDLV+KLLVL+ ++R
Sbjct: 268  LWALGCIIYQLVAGLPPFRAGNEYLIFQKIIKLEYDFPEKFFPKARDLVEKLLVLDATKR 327

Query: 726  LGSGGKAGVERLKAHPFFQGIDWDTLWQQXXXXXXXXXXXXXKHNDPEFRTPTN-----A 890
            LG     G E LKAHPFF+ I W+ L QQ             + ++  +    N      
Sbjct: 328  LGCEEMEGYEPLKAHPFFESITWENLHQQTPPKLTAYLPAMSEDDEDCYGNYDNLLSQFG 387

Query: 891  YLPKLSDNSEVNGSPIATGLRQNDPFRLESWAGG-DDSSDKVD---PEKVKKLEEQKRTS 1058
             +   S +S  + S + T L Q     +E +    D +S ++D    E  K+L  +K+  
Sbjct: 388  CMQVSSSSSSHSLSAVDTSLPQRSGSNIEQYIHDLDTNSFELDLQFSEDEKRLLLEKQAG 447

Query: 1059 AQ-WIPFILKSELIIKTGPINKRKGFFSKKRTLILTDFPRLIYVDQEKNSQKGEIYWSSR 1235
               W  F+ ++ LI+K GP++KRKG F+++R L+LT+ P L YVD      KGEI WS  
Sbjct: 448  GNPWHQFV-ENNLILKMGPVDKRKGLFARRRQLLLTEGPHLYYVDPVNKVLKGEIPWSQE 506

Query: 1236 MVVELKNKRNFFIHTPRKTYYFEDPNNAAHEWVTKINELLVANY 1367
            +  E KN + FF+HTP +TYY  DP+  AH+W  KI E+    Y
Sbjct: 507  LRPEAKNFKTFFVHTPNRTYYLMDPSGNAHKWCRKIQEVWRQRY 550


>ref|XP_012867072.1| PREDICTED: 3-phosphoinositide-dependent protein kinase 1 isoform X1
            [Dipodomys ordii]
          Length = 533

 Score =  418 bits (1075), Expect = e-137
 Identities = 217/466 (46%), Positives = 296/466 (63%), Gaps = 12/466 (2%)
 Frame = +3

Query: 6    LGEGSYSTVVAARDRSNNREYAVXXXXXXXXXXXXXXXYVNIEKNTLNKMNHPGIVRLYY 185
            LGEGS+STVV AR+ + +REYA+               YV  E++ +++++HP  V+LY+
Sbjct: 63   LGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSRLDHPFFVKLYF 122

Query: 186  TFQDPDSLYFVLDHAKNGELLTFIKKLGSFDMDCTKFYASQILSAIEYMHSQGVIHRDLK 365
            TFQD + LYF L +AKNGELL +I+K+GSFD  CT+FY ++I+SA+EY+H +G+IHRDLK
Sbjct: 123  TFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSALEYLHGKGIIHRDLK 182

Query: 366  PENILLDEKMHVKVTDFGTAKILEQNADGEDDDRANSFVGTAEYVSPELLKEKAACKSSD 545
            PENILL+E MH+++TDFGTAK+L   +      RANSFVGTA+YVSPELL EK+ACKSSD
Sbjct: 183  PENILLNEDMHIQITDFGTAKVLSPES---KQARANSFVGTAQYVSPELLTEKSACKSSD 239

Query: 546  FWALGCIIYQLIAGRPPFKGANEYRTFQKIVNLEYSFPDGFPPVARDLVQKLLVLNPSER 725
             WALGCIIYQL+AG PPF+  NEY  FQKI+ LEY FP+ F P ARDLV+KLLVL+ ++R
Sbjct: 240  LWALGCIIYQLVAGLPPFRAGNEYLIFQKIIKLEYDFPEKFFPKARDLVEKLLVLDATKR 299

Query: 726  LGSGGKAGVERLKAHPFFQGIDWDTLWQQXXXXXXXXXXXXXKHNDPEFRTPTN------ 887
            LG     G E LKAHPFF+ I W  L QQ             + ++  +    N      
Sbjct: 300  LGCEEMEGYEPLKAHPFFESILWANLHQQTPPKLTAYLPAMSEDDEDCYGNYDNLLSQFG 359

Query: 888  -AYLPKLSDNSEVNGSPIATGLRQNDPFRLESWAGGDDSSD-----KVDPEKVKKLEEQK 1049
               +   S +S  + S + T L       +E +  G D++      +   ++ K L E++
Sbjct: 360  CMQVSSSSSSSSHSLSAVDTSLPHRSGSNIEQYIHGLDTNSFELDLQFSEDEKKLLLEKQ 419

Query: 1050 RTSAQWIPFILKSELIIKTGPINKRKGFFSKKRTLILTDFPRLIYVDQEKNSQKGEIYWS 1229
                 W  F+ ++ LI+K GP++KRKG F+++R L+LT+ P L YVD      KGEI WS
Sbjct: 420  ACGNPWHQFV-ENNLILKMGPVDKRKGLFARRRQLLLTEGPHLYYVDPVNKVLKGEIPWS 478

Query: 1230 SRMVVELKNKRNFFIHTPRKTYYFEDPNNAAHEWVTKINELLVANY 1367
              +  E KN + FF+HTP +TYY  DP+  AH+W  KI E+    Y
Sbjct: 479  QELRPEAKNFKTFFVHTPNRTYYLMDPSGNAHKWCRKIQEVWRQRY 524


>ref|XP_020024612.1| 3-phosphoinositide-dependent protein kinase 1 isoform X1 [Castor
            canadensis]
          Length = 559

 Score =  419 bits (1077), Expect = e-137
 Identities = 220/464 (47%), Positives = 299/464 (64%), Gaps = 10/464 (2%)
 Frame = +3

Query: 6    LGEGSYSTVVAARDRSNNREYAVXXXXXXXXXXXXXXXYVNIEKNTLNKMNHPGIVRLYY 185
            LGEGS+STVV AR+ + +REYA+               YV  E++ +++++HP  V+LY+
Sbjct: 90   LGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSRLDHPFFVKLYF 149

Query: 186  TFQDPDSLYFVLDHAKNGELLTFIKKLGSFDMDCTKFYASQILSAIEYMHSQGVIHRDLK 365
            TFQD + LYF L +AKNGELL +I+K+GSFD  CT+FY ++I+SA+EY+H +G+IHRDLK
Sbjct: 150  TFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSALEYLHGKGIIHRDLK 209

Query: 366  PENILLDEKMHVKVTDFGTAKILEQNADGEDDDRANSFVGTAEYVSPELLKEKAACKSSD 545
            PENILL+E MH+++TDFGTAK+L   +      RANSFVGTA+YVSPELL EK+ACKSSD
Sbjct: 210  PENILLNEDMHIQITDFGTAKVLSPES---KQARANSFVGTAQYVSPELLTEKSACKSSD 266

Query: 546  FWALGCIIYQLIAGRPPFKGANEYRTFQKIVNLEYSFPDGFPPVARDLVQKLLVLNPSER 725
             WALGCIIYQL+AG PPF+  NEY  FQKI+ LEY FP+ F P ARDLV+KLLVL+ ++R
Sbjct: 267  LWALGCIIYQLVAGLPPFRAGNEYLIFQKIIKLEYDFPEKFFPKARDLVEKLLVLDATKR 326

Query: 726  LGSGGKAGVERLKAHPFFQGIDWDTLWQQXXXXXXXXXXXXXKHNDPEFRTPTN-----A 890
            LG     G E LKAHPFF+ I W+ L QQ             + ++  +    N      
Sbjct: 327  LGCEEMEGYEPLKAHPFFESIMWENLHQQTPPKLTAYLPAMSEDDEDCYGNYDNLLSQFG 386

Query: 891  YLPKLSDNSEVNGSPIATGLRQNDPFRLESWAGG-DDSSDKVD---PEKVKKLEEQKRTS 1058
             +   S +S  + S + TGL       +E +    D +S ++D    E  K+L  +K+  
Sbjct: 387  CMQVSSSSSSHSLSAVDTGLPHRSGSNIEQYIHDLDTNSFELDLQFSEDEKRLLLEKQAG 446

Query: 1059 AQ-WIPFILKSELIIKTGPINKRKGFFSKKRTLILTDFPRLIYVDQEKNSQKGEIYWSSR 1235
               W  F+ ++ LI+K GP++KRKG F+++R L+LT+ P L YVD      KGEI WS  
Sbjct: 447  GNPWHQFV-ENNLILKMGPVDKRKGLFARRRQLLLTEGPHLYYVDPVNKVLKGEIPWSQE 505

Query: 1236 MVVELKNKRNFFIHTPRKTYYFEDPNNAAHEWVTKINELLVANY 1367
            +  E KN + FF+HTP +TYY  DP+  AH+W  KI E+    Y
Sbjct: 506  LRPEAKNFKTFFVHTPNRTYYLMDPSGNAHKWCRKIQEVWRQRY 549


>ref|NP_001273591.1| 3-phosphoinositide-dependent protein kinase 1 isoform C [Mus
            musculus]
 ref|XP_017172809.1| PREDICTED: 3-phosphoinositide-dependent protein kinase 1 isoform X1
            [Mus musculus]
 ref|XP_017172810.1| PREDICTED: 3-phosphoinositide-dependent protein kinase 1 isoform X1
            [Mus musculus]
 ref|XP_017172811.1| PREDICTED: 3-phosphoinositide-dependent protein kinase 1 isoform X1
            [Mus musculus]
 ref|XP_017172812.1| PREDICTED: 3-phosphoinositide-dependent protein kinase 1 isoform X1
            [Mus musculus]
 ref|XP_017172815.1| PREDICTED: 3-phosphoinositide-dependent protein kinase 1 isoform X1
            [Mus musculus]
          Length = 532

 Score =  418 bits (1074), Expect = e-137
 Identities = 219/464 (47%), Positives = 299/464 (64%), Gaps = 10/464 (2%)
 Frame = +3

Query: 6    LGEGSYSTVVAARDRSNNREYAVXXXXXXXXXXXXXXXYVNIEKNTLNKMNHPGIVRLYY 185
            LGEGS+STVV AR+ + +REYA+               YV  E++ +++++HP  V+LY+
Sbjct: 64   LGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSRLDHPFFVKLYF 123

Query: 186  TFQDPDSLYFVLDHAKNGELLTFIKKLGSFDMDCTKFYASQILSAIEYMHSQGVIHRDLK 365
            TFQD + LYF L +AKNGELL +I+K+GSFD  CT+FY ++I+SA+EY+H +G+IHRDLK
Sbjct: 124  TFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSALEYLHGKGIIHRDLK 183

Query: 366  PENILLDEKMHVKVTDFGTAKILEQNADGEDDDRANSFVGTAEYVSPELLKEKAACKSSD 545
            PENILL+E MH+++TDFGTAK+L   +      RANSFVGTA+YVSPELL EK+ACKSSD
Sbjct: 184  PENILLNEDMHIQITDFGTAKVLSPES---KQARANSFVGTAQYVSPELLTEKSACKSSD 240

Query: 546  FWALGCIIYQLIAGRPPFKGANEYRTFQKIVNLEYSFPDGFPPVARDLVQKLLVLNPSER 725
             WALGCIIYQL+AG PPF+  NEY  FQKI+ LEY FP+ F P ARDLV+KLLVL+ ++R
Sbjct: 241  LWALGCIIYQLVAGLPPFRAGNEYLIFQKIIKLEYHFPEKFFPKARDLVEKLLVLDATKR 300

Query: 726  LGSGGKAGVERLKAHPFFQGIDWDTLWQQXXXXXXXXXXXXXKHNDPEFRTPTN-----A 890
            LG     G   LKAHPFF+ I W+ L QQ             + ++  +    N      
Sbjct: 301  LGCEEMEGYGPLKAHPFFETITWENLHQQTPPKLTAYLPAMSEDDEDCYGNYDNLLSQFG 360

Query: 891  YLPKLSDNSEVNGSPIATGLRQNDPFRLESWAGG-DDSSDKVD---PEKVKKLEEQKRTS 1058
            ++   S +S  + S + T L Q     +E +    D +S ++D    E  K+L  +K+  
Sbjct: 361  FMQVSSSSSSHSLSTVETSLPQRSGSNIEQYIHDLDTNSFELDLQFSEDEKRLLLEKQAG 420

Query: 1059 AQ-WIPFILKSELIIKTGPINKRKGFFSKKRTLILTDFPRLIYVDQEKNSQKGEIYWSSR 1235
               W  F+ ++ LI+K GP++KRKG F+++R L+LT+ P L YVD      KGEI WS  
Sbjct: 421  GNPWHQFV-ENNLILKMGPVDKRKGLFARRRQLLLTEGPHLYYVDPVNKVLKGEIPWSQE 479

Query: 1236 MVVELKNKRNFFIHTPRKTYYFEDPNNAAHEWVTKINELLVANY 1367
            +  E KN + FF+HTP +TYY  DP+  AH+W  KI E+    Y
Sbjct: 480  LRPEAKNFKTFFVHTPNRTYYLMDPSGNAHKWCRKIQEVWRQQY 523


>gb|AAL47185.1| phosphoinositide-dependent protein kinase-1 beta [Mus musculus]
          Length = 532

 Score =  418 bits (1074), Expect = e-137
 Identities = 219/464 (47%), Positives = 299/464 (64%), Gaps = 10/464 (2%)
 Frame = +3

Query: 6    LGEGSYSTVVAARDRSNNREYAVXXXXXXXXXXXXXXXYVNIEKNTLNKMNHPGIVRLYY 185
            LGEGS+STVV AR+ + +REYA+               YV  E++ +++++HP  V+LY+
Sbjct: 64   LGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSRLDHPFFVKLYF 123

Query: 186  TFQDPDSLYFVLDHAKNGELLTFIKKLGSFDMDCTKFYASQILSAIEYMHSQGVIHRDLK 365
            TFQD + LYF L +AKNGELL +I+K+GSFD  CT+FY ++I+SA+EY+H +G+IHRDLK
Sbjct: 124  TFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSALEYLHGKGIIHRDLK 183

Query: 366  PENILLDEKMHVKVTDFGTAKILEQNADGEDDDRANSFVGTAEYVSPELLKEKAACKSSD 545
            PENILL+E MH+++TDFGTAK+L   +      RANSFVGTA+YVSPELL EK+ACKSSD
Sbjct: 184  PENILLNEDMHIQITDFGTAKVLSPES---KQARANSFVGTAQYVSPELLTEKSACKSSD 240

Query: 546  FWALGCIIYQLIAGRPPFKGANEYRTFQKIVNLEYSFPDGFPPVARDLVQKLLVLNPSER 725
             WALGCIIYQL+AG PPF+  NEY  FQKI+ LEY FP+ F P ARDLV+KLLVL+ ++R
Sbjct: 241  LWALGCIIYQLVAGLPPFRAGNEYLIFQKIIKLEYHFPEKFFPKARDLVEKLLVLDATKR 300

Query: 726  LGSGGKAGVERLKAHPFFQGIDWDTLWQQXXXXXXXXXXXXXKHNDPEFRTPTN-----A 890
            LG     G   LKAHPFF+ I W+ L QQ             + ++  +    N      
Sbjct: 301  LGCEEMEGYGPLKAHPFFETITWENLHQQTPPKLTAYLPAMSEDDEDCYGNYDNLLSQFG 360

Query: 891  YLPKLSDNSEVNGSPIATGLRQNDPFRLESWAGG-DDSSDKVD---PEKVKKLEEQKRTS 1058
            ++   S +S  + S + T L Q     +E +    D +S ++D    E  K+L  +K+  
Sbjct: 361  FMQVSSSSSSHSLSTVETSLPQRSGSNIEQYIHDLDTNSFELDLQFSEDEKRLLLEKQAG 420

Query: 1059 AQ-WIPFILKSELIIKTGPINKRKGFFSKKRTLILTDFPRLIYVDQEKNSQKGEIYWSSR 1235
               W  F+ ++ LI+K GP++KRKG F+++R L+LT+ P L YVD      KGEI WS  
Sbjct: 421  GNPWHQFV-ENNLILKMGPVDKRKGLFARRRQLLLTEGPHLYYVDPVNKVLKGEIPWSQE 479

Query: 1236 MVVELKNKRNFFIHTPRKTYYFEDPNNAAHEWVTKINELLVANY 1367
            +  E KN + FF+HTP +TYY  DP+  AH+W  KI E+    Y
Sbjct: 480  LRPEAKNFKTFFVHTPNRTYYLMDPSGNAHKWCRKIQEVWRQQY 523