BLASTX 2.2.26 [Sep-21-2011]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= Ophiopogon23_contig00032002
         (3070 letters)

Database: All non-redundant GenBank CDS
translations+PDB+SwissProt+PIR+PRF excluding environmental samples
from WGS projects 
           149,584,005 sequences; 54,822,741,787 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

ref|XP_020262391.1| LOW QUALITY PROTEIN: DNA topoisomerase 2-lik...  1357   0.0  
gb|ONK71489.1| uncharacterized protein A4U43_C04F9180 [Asparagus...  1357   0.0  
ref|XP_008779357.2| PREDICTED: DNA topoisomerase 2 [Phoenix dact...  1214   0.0  
ref|XP_010920068.1| PREDICTED: DNA topoisomerase 2 [Elaeis guine...  1197   0.0  
gb|OAY66581.1| DNA topoisomerase 2 [Ananas comosus]                  1180   0.0  
ref|XP_010241213.1| PREDICTED: DNA topoisomerase 2-like isoform ...  1167   0.0  
ref|XP_010241214.1| PREDICTED: DNA topoisomerase 2-like isoform ...  1166   0.0  
ref|XP_020703085.1| DNA topoisomerase 2-like [Dendrobium catenat...  1160   0.0  
ref|XP_009399445.1| PREDICTED: DNA topoisomerase 2-like [Musa ac...  1158   0.0  
ref|XP_020693654.1| DNA topoisomerase 2 [Dendrobium catenatum] >...  1155   0.0  
ref|XP_009402954.1| PREDICTED: DNA topoisomerase 2-like [Musa ac...  1154   0.0  
ref|XP_020577441.1| DNA topoisomerase 2 [Phalaenopsis equestris]     1138   0.0  
gb|OVA19386.1| DNA topoisomerase II [Macleaya cordata]               1134   0.0  
ref|XP_002274267.1| PREDICTED: DNA topoisomerase 2 [Vitis vinifera]  1124   0.0  
emb|CDP07797.1| unnamed protein product [Coffea canephora]           1117   0.0  
gb|EOY18138.1| DNA topoisomerase 2 isoform 2 [Theobroma cacao]       1110   0.0  
ref|XP_010023678.1| PREDICTED: DNA topoisomerase 2 [Eucalyptus g...  1107   0.0  
ref|XP_021295966.1| DNA topoisomerase 2 [Herrania umbratica]         1106   0.0  
ref|XP_006345427.1| PREDICTED: DNA topoisomerase 2 isoform X3 [S...  1093   0.0  
ref|XP_015163347.1| PREDICTED: DNA topoisomerase 2 isoform X2 [S...  1093   0.0  

>ref|XP_020262391.1| LOW QUALITY PROTEIN: DNA topoisomerase 2-like [Asparagus officinalis]
          Length = 1489

 Score = 1357 bits (3512), Expect = 0.0
 Identities = 700/982 (71%), Positives = 770/982 (78%), Gaps = 5/982 (0%)
 Frame = +3

Query: 3    KGKLLNVREASLKQIMQNAEIQNIKQILGLQHGKQYDSVKGLRYGSLMIMTDQDHDGSHI 182
            KGKLLNVREASLKQIMQN EIQ++KQILGLQ  K+YDSVKGLRYG LMIMTDQDHDGSHI
Sbjct: 488  KGKLLNVREASLKQIMQNDEIQHLKQILGLQQDKKYDSVKGLRYGHLMIMTDQDHDGSHI 547

Query: 183  KGLLINFIHSFWPSLLKVKGFMVEFITPIVKASHKNGTVLSFYTMPEYEAWKESLNGNAT 362
            KGLLINFIHSFWPSLLK+ GFM EFITPIVKAS KNG VLSFY+MPEYEAWKESLNGNA+
Sbjct: 548  KGLLINFIHSFWPSLLKINGFMEEFITPIVKASRKNGEVLSFYSMPEYEAWKESLNGNAS 607

Query: 363  GWTIKYYKGLGTSTAKEGKEYFKQLRKHKKSFVWADEQDGESIELAFSKKKIEARKNWLR 542
            GWTIKYYKGLGTST+KEGKEYF+Q+RKHKKSF+W+D+QDGE+IELAFSKKKIEARKNWLR
Sbjct: 608  GWTIKYYKGLGTSTSKEGKEYFRQIRKHKKSFIWSDDQDGEAIELAFSKKKIEARKNWLR 667

Query: 543  QFEAGTYLDHKEEEIKYSDFVNKELILFSRADLQRSIPSMVDGLKPGQRKILFCAFKRNL 722
            QFE GTYLD + E+I YSDFVNKELILFSRADLQRSIPSMVDGLKPGQRKILFCAFKRN 
Sbjct: 668  QFEPGTYLDQEGEKITYSDFVNKELILFSRADLQRSIPSMVDGLKPGQRKILFCAFKRNF 727

Query: 723  IKEAKVAQFSGYVSEHSAYHHGEQSLASTIVGMAQDFVGSNNINLFQPKGQFGTRNKGGK 902
            +KEAKVAQFSGYVSEHSAYHHGEQSL STIVGMAQDFVGSNNINLFQP GQFGTRN+GGK
Sbjct: 728  VKEAKVAQFSGYVSEHSAYHHGEQSLVSTIVGMAQDFVGSNNINLFQPNGQFGTRNRGGK 787

Query: 903  DAASGRYIYTCLSPITRFLFPKXXXXXXXXXXXXGQSIEPAWYMPIIPMVLVNGSEGIGT 1082
            DAASGRYIYTCLSPITR+LFPK            GQSIEP+WY+PIIPMVL+NGSEGIGT
Sbjct: 788  DAASGRYIYTCLSPITRYLFPKDDDLLLDYLDEDGQSIEPSWYVPIIPMVLINGSEGIGT 847

Query: 1083 GWSSYVPNYNPRDVVANVRRLLNDEPMRPMEPWYRGFKGLIEKSAQKETGVTYTISGIIE 1262
            GWSSYVPNYNPRDV+ANVRRLLNDEPM+PM+PWYRGF+G+I KSA+KETGVTYTISGIIE
Sbjct: 848  GWSSYVPNYNPRDVIANVRRLLNDEPMQPMDPWYRGFQGIIWKSAEKETGVTYTISGIIE 907

Query: 1263 EVDITTLRITELPIRSWTADYNEFLDAMMKGTDKFKEPFIQDKRAYNDDVIVHFEVILSE 1442
            EVD +TLRITELPIRSWT +YNEFL+AMM GTDKFKEPFIQDK+AYNDD  VHFE++LSE
Sbjct: 908  EVDSSTLRITELPIRSWTLEYNEFLEAMMNGTDKFKEPFIQDKKAYNDDTTVHFEIMLSE 967

Query: 1443 ENMMAAKQEGXXXXXXXXXXISTSNMHLFDSNGTIKKYDTPEQILEDFFHLRLQFYEKRK 1622
            +NM  AKQEG          IST+NMHLFD +G IKKYDTPEQILEDFFHLRL+FYEKR+
Sbjct: 968  QNMEVAKQEGLEKKFKLTNTISTTNMHLFDPSGVIKKYDTPEQILEDFFHLRLEFYEKRR 1027

Query: 1623 KVXXXXXXXXXXXXXXXVRFILAVVKGEIIVNNRRRADLFLELHQKGFTPFPKKTKGIDA 1802
            K+               VRFIL VV+GEIIVNNR+R DLFLELHQKGFTPFPKKTKGIDA
Sbjct: 1028 KILLDNLEFDLLKLDNKVRFILGVVRGEIIVNNRKRVDLFLELHQKGFTPFPKKTKGIDA 1087

Query: 1803 AIAGATVDTXXXXXXXXXTVKGVVKASDYEYLLSMSIGSLTLEKVQELCADKQKLDHELE 1982
            AIAGATV+T          VKG VKASDYEYLLS++IG+LTLEKVQ LCADK++L+HELE
Sbjct: 1088 AIAGATVETEENEEESPEMVKGAVKASDYEYLLSLAIGTLTLEKVQALCADKERLEHELE 1147

Query: 1983 ELRSTSSKILWMRDLDALEKQLDELDQKDVEAANMQEKIRRR-NTGAAVPSKAPKKPRKN 2159
             LRSTS + LWMRDLDALE QLDE DQ+D  AA  ++++R + N GAAV  KAPK  +KN
Sbjct: 1148 MLRSTSPRALWMRDLDALEAQLDEHDQQDAVAAKTRQEMRAKINKGAAVSRKAPKPLKKN 1207

Query: 2160 NAIKGPTVAANDADVGTTSTAMDAGNXXXXXXXXXXXXXXXDAAKKTTVVXXXXXXXXXX 2339
            N  K        A VG+TSTA +AGN                 AKK TVV          
Sbjct: 1208 NTTKSIAATETGATVGSTSTATEAGNVTEVAKPKPRGGQKKAPAKKATVVDSDDDEVLEL 1267

Query: 2340 KDRLAAYNLDSSPDQTFMETESVAQEVLKMKAPSKRATVRKGKSTMTILXXXXXXXXXXX 2519
            KDRLAAYNLDSSPDQT METE+V +     K  +KRA  RK KST+TI            
Sbjct: 1268 KDRLAAYNLDSSPDQTSMETEAVGK-----KEANKRAAARKPKSTLTISDDDDDMNAEEM 1322

Query: 2520 PAISEDG-DDGDFQMVEV---XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXQGKSLVSQ 2687
            P I EDG DD DF+M+E                                   +GKSL+SQ
Sbjct: 1323 PTIVEDGDDDADFEMMEAAPKGKKGGAGRKPANAKAKGTTTMTTARKRGGGAKGKSLLSQ 1382

Query: 2688 KLITDVLKPVVNASPEKKVRKMRESPFNKKSGSVLGRARGPVVESEGSIDSSPSVNLEVE 2867
            K ITD+LKPV NASPEKKVRKMRESPFNKKSGSVLGRA G + ESEGS+ S  SVNLE  
Sbjct: 1383 KAITDMLKPVENASPEKKVRKMRESPFNKKSGSVLGRAGGSMTESEGSVGSLSSVNLEAG 1442

Query: 2868 MNEVPVARNRPKRENRSKVQYV 2933
             + V V RN PKRENR KV YV
Sbjct: 1443 RDVVQVTRNLPKRENRKKVTYV 1464


>gb|ONK71489.1| uncharacterized protein A4U43_C04F9180 [Asparagus officinalis]
          Length = 1419

 Score = 1357 bits (3512), Expect = 0.0
 Identities = 700/982 (71%), Positives = 770/982 (78%), Gaps = 5/982 (0%)
 Frame = +3

Query: 3    KGKLLNVREASLKQIMQNAEIQNIKQILGLQHGKQYDSVKGLRYGSLMIMTDQDHDGSHI 182
            KGKLLNVREASLKQIMQN EIQ++KQILGLQ  K+YDSVKGLRYG LMIMTDQDHDGSHI
Sbjct: 418  KGKLLNVREASLKQIMQNDEIQHLKQILGLQQDKKYDSVKGLRYGHLMIMTDQDHDGSHI 477

Query: 183  KGLLINFIHSFWPSLLKVKGFMVEFITPIVKASHKNGTVLSFYTMPEYEAWKESLNGNAT 362
            KGLLINFIHSFWPSLLK+ GFM EFITPIVKAS KNG VLSFY+MPEYEAWKESLNGNA+
Sbjct: 478  KGLLINFIHSFWPSLLKINGFMEEFITPIVKASRKNGEVLSFYSMPEYEAWKESLNGNAS 537

Query: 363  GWTIKYYKGLGTSTAKEGKEYFKQLRKHKKSFVWADEQDGESIELAFSKKKIEARKNWLR 542
            GWTIKYYKGLGTST+KEGKEYF+Q+RKHKKSF+W+D+QDGE+IELAFSKKKIEARKNWLR
Sbjct: 538  GWTIKYYKGLGTSTSKEGKEYFRQIRKHKKSFIWSDDQDGEAIELAFSKKKIEARKNWLR 597

Query: 543  QFEAGTYLDHKEEEIKYSDFVNKELILFSRADLQRSIPSMVDGLKPGQRKILFCAFKRNL 722
            QFE GTYLD + E+I YSDFVNKELILFSRADLQRSIPSMVDGLKPGQRKILFCAFKRN 
Sbjct: 598  QFEPGTYLDQEGEKITYSDFVNKELILFSRADLQRSIPSMVDGLKPGQRKILFCAFKRNF 657

Query: 723  IKEAKVAQFSGYVSEHSAYHHGEQSLASTIVGMAQDFVGSNNINLFQPKGQFGTRNKGGK 902
            +KEAKVAQFSGYVSEHSAYHHGEQSL STIVGMAQDFVGSNNINLFQP GQFGTRN+GGK
Sbjct: 658  VKEAKVAQFSGYVSEHSAYHHGEQSLVSTIVGMAQDFVGSNNINLFQPNGQFGTRNRGGK 717

Query: 903  DAASGRYIYTCLSPITRFLFPKXXXXXXXXXXXXGQSIEPAWYMPIIPMVLVNGSEGIGT 1082
            DAASGRYIYTCLSPITR+LFPK            GQSIEP+WY+PIIPMVL+NGSEGIGT
Sbjct: 718  DAASGRYIYTCLSPITRYLFPKDDDLLLDYLDEDGQSIEPSWYVPIIPMVLINGSEGIGT 777

Query: 1083 GWSSYVPNYNPRDVVANVRRLLNDEPMRPMEPWYRGFKGLIEKSAQKETGVTYTISGIIE 1262
            GWSSYVPNYNPRDV+ANVRRLLNDEPM+PM+PWYRGF+G+I KSA+KETGVTYTISGIIE
Sbjct: 778  GWSSYVPNYNPRDVIANVRRLLNDEPMQPMDPWYRGFQGIIWKSAEKETGVTYTISGIIE 837

Query: 1263 EVDITTLRITELPIRSWTADYNEFLDAMMKGTDKFKEPFIQDKRAYNDDVIVHFEVILSE 1442
            EVD +TLRITELPIRSWT +YNEFL+AMM GTDKFKEPFIQDK+AYNDD  VHFE++LSE
Sbjct: 838  EVDSSTLRITELPIRSWTLEYNEFLEAMMNGTDKFKEPFIQDKKAYNDDTTVHFEIMLSE 897

Query: 1443 ENMMAAKQEGXXXXXXXXXXISTSNMHLFDSNGTIKKYDTPEQILEDFFHLRLQFYEKRK 1622
            +NM  AKQEG          IST+NMHLFD +G IKKYDTPEQILEDFFHLRL+FYEKR+
Sbjct: 898  QNMEVAKQEGLEKKFKLTNTISTTNMHLFDPSGVIKKYDTPEQILEDFFHLRLEFYEKRR 957

Query: 1623 KVXXXXXXXXXXXXXXXVRFILAVVKGEIIVNNRRRADLFLELHQKGFTPFPKKTKGIDA 1802
            K+               VRFIL VV+GEIIVNNR+R DLFLELHQKGFTPFPKKTKGIDA
Sbjct: 958  KILLDNLEFDLLKLDNKVRFILGVVRGEIIVNNRKRVDLFLELHQKGFTPFPKKTKGIDA 1017

Query: 1803 AIAGATVDTXXXXXXXXXTVKGVVKASDYEYLLSMSIGSLTLEKVQELCADKQKLDHELE 1982
            AIAGATV+T          VKG VKASDYEYLLS++IG+LTLEKVQ LCADK++L+HELE
Sbjct: 1018 AIAGATVETEENEEESPEMVKGAVKASDYEYLLSLAIGTLTLEKVQALCADKERLEHELE 1077

Query: 1983 ELRSTSSKILWMRDLDALEKQLDELDQKDVEAANMQEKIRRR-NTGAAVPSKAPKKPRKN 2159
             LRSTS + LWMRDLDALE QLDE DQ+D  AA  ++++R + N GAAV  KAPK  +KN
Sbjct: 1078 MLRSTSPRALWMRDLDALEAQLDEHDQQDAVAAKTRQEMRAKINKGAAVSRKAPKPLKKN 1137

Query: 2160 NAIKGPTVAANDADVGTTSTAMDAGNXXXXXXXXXXXXXXXDAAKKTTVVXXXXXXXXXX 2339
            N  K        A VG+TSTA +AGN                 AKK TVV          
Sbjct: 1138 NTTKSIAATETGATVGSTSTATEAGNVTEVAKPKPRGGQKKAPAKKATVVDSDDDEVLEL 1197

Query: 2340 KDRLAAYNLDSSPDQTFMETESVAQEVLKMKAPSKRATVRKGKSTMTILXXXXXXXXXXX 2519
            KDRLAAYNLDSSPDQT METE+V +     K  +KRA  RK KST+TI            
Sbjct: 1198 KDRLAAYNLDSSPDQTSMETEAVGK-----KEANKRAAARKPKSTLTISDDDDDMNAEEM 1252

Query: 2520 PAISEDG-DDGDFQMVEV---XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXQGKSLVSQ 2687
            P I EDG DD DF+M+E                                   +GKSL+SQ
Sbjct: 1253 PTIVEDGDDDADFEMMEAAPKGKKGGAGRKPANAKAKGTTTMTTARKRGGGAKGKSLLSQ 1312

Query: 2688 KLITDVLKPVVNASPEKKVRKMRESPFNKKSGSVLGRARGPVVESEGSIDSSPSVNLEVE 2867
            K ITD+LKPV NASPEKKVRKMRESPFNKKSGSVLGRA G + ESEGS+ S  SVNLE  
Sbjct: 1313 KAITDMLKPVENASPEKKVRKMRESPFNKKSGSVLGRAGGSMTESEGSVGSLSSVNLEAG 1372

Query: 2868 MNEVPVARNRPKRENRSKVQYV 2933
             + V V RN PKRENR KV YV
Sbjct: 1373 RDVVQVTRNLPKRENRKKVTYV 1394


>ref|XP_008779357.2| PREDICTED: DNA topoisomerase 2 [Phoenix dactylifera]
          Length = 1378

 Score = 1214 bits (3142), Expect = 0.0
 Identities = 638/982 (64%), Positives = 727/982 (74%), Gaps = 5/982 (0%)
 Frame = +3

Query: 3    KGKLLNVREASLKQIMQNAEIQNIKQILGLQHGKQYDSVKGLRYGSLMIMTDQDHDGSHI 182
            +GKLLNVREAS KQIM+NAEIQNIKQILGLQHGK+YDS KGLRYG LMIMTDQDHDGSHI
Sbjct: 386  RGKLLNVREASHKQIMENAEIQNIKQILGLQHGKEYDSTKGLRYGHLMIMTDQDHDGSHI 445

Query: 183  KGLLINFIHSFWPSLLKVKGFMVEFITPIVKASH-KNGTVLSFYTMPEYEAWKESLNGNA 359
            KGLLINFIHSFWPSLLK+  FMVEFITPIVKA+H KN TVL FY+MPEYEAWKE L GNA
Sbjct: 446  KGLLINFIHSFWPSLLKIPSFMVEFITPIVKATHSKNKTVLPFYSMPEYEAWKERLGGNA 505

Query: 360  TGWTIKYYKGLGTSTAKEGKEYFKQLRKHKKSFVWADEQDGESIELAFSKKKIEARKNWL 539
            +GW+IKYYKGLGTST+KEGKEYF  + KHKK F+W D+QDG++IELAFSKKKIEARKNWL
Sbjct: 506  SGWSIKYYKGLGTSTSKEGKEYFHDIDKHKKDFIWVDDQDGDAIELAFSKKKIEARKNWL 565

Query: 540  RQFEAGTYLDHKEEEIKYSDFVNKELILFSRADLQRSIPSMVDGLKPGQRKILFCAFKRN 719
            R FE GTYLD +++ IKYSDFVNKELILFS ADLQRSIPS VDGLKPGQRKILFC+FKRN
Sbjct: 566  RHFETGTYLDQRQKHIKYSDFVNKELILFSMADLQRSIPSTVDGLKPGQRKILFCSFKRN 625

Query: 720  LIKEAKVAQFSGYVSEHSAYHHGEQSLASTIVGMAQDFVGSNNINLFQPKGQFGTRNKGG 899
             +KEAKVAQFSGYVSEHSAYHHGEQSLASTI+GMAQDFVGSNNINL QP GQFGTR++GG
Sbjct: 626  FVKEAKVAQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLQPNGQFGTRHQGG 685

Query: 900  KDAASGRYIYTCLSPITRFLFPKXXXXXXXXXXXXGQSIEPAWYMPIIPMVLVNGSEGIG 1079
            KD AS RYIYT LSP+TRFLFPK            GQSIEP WYMPIIP+VLVNGSEGIG
Sbjct: 686  KDHASARYIYTRLSPLTRFLFPKDDDMLLDYLNEDGQSIEPTWYMPIIPLVLVNGSEGIG 745

Query: 1080 TGWSSYVPNYNPRDVVANVRRLLNDEPMRPMEPWYRGFKGLIEKSAQKETGVTYTISGII 1259
            TGWSS+VPNYNPRD+VANVRRLLNDEPM+PM+PWYRGFKGLIEKSA KE GVTYTI+G+I
Sbjct: 746  TGWSSFVPNYNPRDIVANVRRLLNDEPMQPMDPWYRGFKGLIEKSATKEAGVTYTITGLI 805

Query: 1260 EEVDITTLRITELPIRSWTADYNEFLDAMMKGTDKFKEPFIQDKRAYNDDVIVHFEVILS 1439
            EEVD TTLRITELPIR WT DY EFL++MM G DK KEPFI+D R +NDD+ VHFE+IL+
Sbjct: 806  EEVDSTTLRITELPIRRWTQDYKEFLESMMTGNDKIKEPFIKDYREHNDDINVHFEIILT 865

Query: 1440 EENMMAAKQEGXXXXXXXXXXISTSNMHLFDSNGTIKKYDTPEQILEDFFHLRLQFYEKR 1619
            EE +  AK+EG          IST+NMHLFDS G IKKYDTPEQILEDFFHLRL++Y KR
Sbjct: 866  EEKLKMAKEEGLERKFKLTTTISTTNMHLFDSEGVIKKYDTPEQILEDFFHLRLEYYAKR 925

Query: 1620 KKVXXXXXXXXXXXXXXXVRFILAVVKGEIIVNNRRRADLFLELHQKGFTPFPKKTKGID 1799
            KKV               VRFIL VV+GEIIV+NR+RADLFLEL QKGFTPFPKK+KGID
Sbjct: 926  KKVLLDNLEMDLLKLDNKVRFILGVVRGEIIVSNRKRADLFLELQQKGFTPFPKKSKGID 985

Query: 1800 AAIAGATVDTXXXXXXXXXTVKGVVKASDYEYLLSMSIGSLTLEKVQELCADKQKLDHEL 1979
            AAIAGAT +          + +   +A+DYEYLLSM+IG+LT EKVQELCAD++KL+ E+
Sbjct: 986  AAIAGATEE-----DDNEESPEVAARATDYEYLLSMAIGTLTWEKVQELCADRKKLEGEV 1040

Query: 1980 EELRSTSSKILWMRDLDALEKQLDELDQKDVEAANMQEKIRRRNTGAAVPSKAPKKPRKN 2159
            EEL+ +S + LWM+DLD  E++LDEL++KD E    +E   +  TGAAV  + PKKPRKN
Sbjct: 1041 EELKKSSPRDLWMKDLDDFERELDELERKDAEEGMKRETRTKNITGAAVSRQGPKKPRKN 1100

Query: 2160 NAIKGPTVAANDADVGTTSTAMDAGNXXXXXXXXXXXXXXXDAAKKTTVV-XXXXXXXXX 2336
            N        AN++   +  T+ DAGN                 AKK  VV          
Sbjct: 1101 N--------ANNSSSISNVTSTDAGNAPEPSKLKARGGAKKAPAKKVMVVESDEDEEVLA 1152

Query: 2337 XKDRLAAYNLDSSPDQTFMETE-SVAQEVLKMKAPSKRATVRKGKSTMTILXXXXXXXXX 2513
             KDRLAAYNLDSSPDQ+ ME E +++Q   + K PSKR  +RK  ST T +         
Sbjct: 1153 LKDRLAAYNLDSSPDQSAMEAEAALSQREHRKKEPSKRTALRKAPSTFTEI-SDGDDVED 1211

Query: 2514 XXPAISEDGDDGDFQMVEVXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXQGKSLVSQKL 2693
              P + ED DD DF++ E                                Q K ++SQKL
Sbjct: 1212 NMPIVGED-DDEDFELAEAPKGGQARGRKPANEKAKRGKATTTTRKRGAAQSKPVLSQKL 1270

Query: 2694 ITDVLKPVVNA--SPEKKVRKMRESPFNKKSGSVLGRARGPVVESEGSIDSSPSVNLEVE 2867
            IT+VLKPV NA  SP+KKVRKMR SPFNKKSG VLGR      +SE S   S S     E
Sbjct: 1271 ITEVLKPVENAGISPDKKVRKMRASPFNKKSGPVLGRTGSSPTDSEES--GSHSSGSPAE 1328

Query: 2868 MNEVPVARNRPKRENRSKVQYV 2933
            MNEVPVA  RPKR NR +  Y+
Sbjct: 1329 MNEVPVAAPRPKRGNRIRAVYM 1350


>ref|XP_010920068.1| PREDICTED: DNA topoisomerase 2 [Elaeis guineensis]
          Length = 1486

 Score = 1197 bits (3098), Expect = 0.0
 Identities = 637/987 (64%), Positives = 721/987 (73%), Gaps = 10/987 (1%)
 Frame = +3

Query: 3    KGKLLNVREASLKQIMQNAEIQNIKQILGLQHGKQYDSVKGLRYGSLMIMTDQDHDGSHI 182
            +GKLLNVREAS KQIM NAEIQ+IKQILGLQ GK+Y+S KGLRYG LMIMTDQDHDGSHI
Sbjct: 488  RGKLLNVREASHKQIMDNAEIQSIKQILGLQQGKEYESTKGLRYGHLMIMTDQDHDGSHI 547

Query: 183  KGLLINFIHSFWPSLLKVKGFMVEFITPIVKASH-KNGTVLSFYTMPEYEAWKESLNGNA 359
            KGLLINFIHSFWPSLLK+  FMVEFITPIVKA+H +N  VL FY+MPEYEAWKESL GNA
Sbjct: 548  KGLLINFIHSFWPSLLKIPSFMVEFITPIVKATHNRNKNVLPFYSMPEYEAWKESLGGNA 607

Query: 360  TGWTIKYYKGLGTSTAKEGKEYFKQLRKHKKSFVWADEQDGESIELAFSKKKIEARKNWL 539
            +GW+IKYYKGLGTST+KEGKEYF+ + KHKK F+W D QDG++IELAFSKKKIEARKNWL
Sbjct: 608  SGWSIKYYKGLGTSTSKEGKEYFQDIVKHKKDFMWVDNQDGDAIELAFSKKKIEARKNWL 667

Query: 540  RQFEAGTYLDHKEEEIKYSDFVNKELILFSRADLQRSIPSMVDGLKPGQRKILFCAFKRN 719
            RQFE GTYLD +E+ IKYSDFVNKELILFS ADLQRSIPSMVDGLKPGQRKILFC+FKRN
Sbjct: 668  RQFEPGTYLDQREKLIKYSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKILFCSFKRN 727

Query: 720  LIKEAKVAQFSGYVSEHSAYHHGEQSLASTIVGMAQDFVGSNNINLFQPKGQFGTRNKGG 899
             +KEAKVAQF+GYVSEHSAYHHGEQSLASTI+GMAQDFVGSNNINL QP GQFGTR++GG
Sbjct: 728  FVKEAKVAQFAGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLQPNGQFGTRHQGG 787

Query: 900  KDAASGRYIYTCLSPITRFLFPKXXXXXXXXXXXXGQSIEPAWYMPIIPMVLVNGSEGIG 1079
            KD AS RYIYT LSP+TRFLFPK            GQ IEP WYMPIIPMVLVNGSEGIG
Sbjct: 788  KDHASARYIYTRLSPLTRFLFPKDDDILLDYLNEDGQLIEPTWYMPIIPMVLVNGSEGIG 847

Query: 1080 TGWSSYVPNYNPRDVVANVRRLLNDEPMRPMEPWYRGFKGLIEKSAQKETGVTYTISGII 1259
            TGWS++VPNYNPRD+VANVRRLLN+EPM+PM+PWYR FKGLIEKSA KE GVTYTI+G+ 
Sbjct: 848  TGWSTFVPNYNPRDIVANVRRLLNNEPMQPMDPWYRSFKGLIEKSASKEAGVTYTITGLA 907

Query: 1260 EEVDITTLRITELPIRSWTADYNEFLDAMMKGTDKFKEPFIQDKRAYNDDVIVHFEVILS 1439
            EEVD TTL+ITELPIR WT DY EFL+++M G DK KEPFI+D R  NDDV VHFE+IL+
Sbjct: 908  EEVDSTTLKITELPIRRWTQDYKEFLESLMTGNDKIKEPFIKDYREQNDDVNVHFEIILT 967

Query: 1440 EENMMAAKQEGXXXXXXXXXXISTSNMHLFDSNGTIKKYDTPEQILEDFFHLRLQFYEKR 1619
            EE +  A++EG          IST+NMHLFDS G IKKYDTPEQILEDFFHLRL+FY KR
Sbjct: 968  EEKLNMAREEGLEKKFKLTTTISTTNMHLFDSKGVIKKYDTPEQILEDFFHLRLEFYAKR 1027

Query: 1620 KKVXXXXXXXXXXXXXXXVRFILAVVKGEIIVNNRRRADLFLELHQKGFTPFPKKTKGID 1799
            KK                VRFIL VV+GEIIVNNR+RADLFLEL QKGF PFPKK+KGID
Sbjct: 1028 KKALLDNLELDLLKLDNKVRFILGVVRGEIIVNNRKRADLFLELQQKGFAPFPKKSKGID 1087

Query: 1800 AAIAGATVDTXXXXXXXXXTVKGVVKASDYEYLLSMSIGSLTLEKVQELCADKQKLDHEL 1979
            AAIAGATV+             G  +A+DYEYLLSM+IG+LT EKVQELCA+++KL+ E+
Sbjct: 1088 AAIAGATVEEDGNEESPEVVNGGGARAADYEYLLSMAIGTLTWEKVQELCAERKKLEDEV 1147

Query: 1980 EELRSTSSKILWMRDLDALEKQLDELDQKDVEAANMQEKIRRRNTGAAVPSKAPKKPRKN 2159
            EELR +S + LWM+DLDA E +LDE ++KD E    +E   +  TGAA+  + PKKPRKN
Sbjct: 1148 EELRKSSPRDLWMKDLDAFEMELDEQERKDAEEGIKRETRMKNITGAALSKQGPKKPRKN 1207

Query: 2160 NAIKGPTVAANDADVGTTSTAMDAGNXXXXXXXXXXXXXXXDAAKKTTVV---XXXXXXX 2330
            NA    TV    +DV    T+ DAGN                 AKK  VV          
Sbjct: 1208 NANNSSTV----SDV----TSTDAGNAPEASKPKPRGRAKKAPAKKVAVVESDEDDEEEV 1259

Query: 2331 XXXKDRLAAYNLDSSPD-QTFMETESV-AQEVLKMKAPSKRATVRKGKSTMTILXXXXXX 2504
               KDRLAAYNLDSSPD Q+ METE+V +Q+  + K PSKR   RK  ST T +      
Sbjct: 1260 LALKDRLAAYNLDSSPDHQSAMETEAVLSQKEQRKKEPSKRTAARKAPSTFTEI-SDGDD 1318

Query: 2505 XXXXXPAISEDGDDGDFQMVEV--XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXQGKSL 2678
                 P I ED DD DF++VE                                  Q K +
Sbjct: 1319 AEDDMPTILEDDDDEDFELVEAPPKGGKARGKKPANEKAKGGKAGTTTTRKRGTAQSKPV 1378

Query: 2679 VSQKLITDVLKPVVNA--SPEKKVRKMRESPFNKKSGSVLGRARGPVVESEGSIDSSPSV 2852
            +SQKLIT+VLKPV N   SPEKKVRKMR SPFNKKSGSVLGR       SE S  SSP  
Sbjct: 1379 LSQKLITEVLKPVENTGISPEKKVRKMRASPFNKKSGSVLGRIGSSPTSSEESGSSSP-- 1436

Query: 2853 NLEVEMNEVPVARNRPKRENRSKVQYV 2933
                E+NEV  A  RPKREN  +  Y+
Sbjct: 1437 GNPAELNEVLAAAARPKRENSRRAVYI 1463


>gb|OAY66581.1| DNA topoisomerase 2 [Ananas comosus]
          Length = 1476

 Score = 1180 bits (3053), Expect = 0.0
 Identities = 617/982 (62%), Positives = 704/982 (71%), Gaps = 5/982 (0%)
 Frame = +3

Query: 3    KGKLLNVREASLKQIMQNAEIQNIKQILGLQHGKQYDSVKGLRYGSLMIMTDQDHDGSHI 182
            +GKLLNVR+A+ KQIM NAEIQNIK ILGLQHGKQYDS KGLRYG LMIMTDQDHDGSHI
Sbjct: 486  RGKLLNVRDANHKQIMDNAEIQNIKLILGLQHGKQYDSTKGLRYGHLMIMTDQDHDGSHI 545

Query: 183  KGLLINFIHSFWPSLLKVKGFMVEFITPIVKASH-KNGTVLSFYTMPEYEAWKESLNGNA 359
            KGLLINF+HSFWPSLLK+  FMVEFITPIVKA+H +N TVLSFY+MPEYEAWKESL G+A
Sbjct: 546  KGLLINFVHSFWPSLLKIPSFMVEFITPIVKATHNRNKTVLSFYSMPEYEAWKESLGGSA 605

Query: 360  TGWTIKYYKGLGTSTAKEGKEYFKQLRKHKKSFVWADEQDGESIELAFSKKKIEARKNWL 539
             GW+IKYYKGLGTST+KEGKEYF+ + KHKK FVW DEQDG++I+LAFSKKKIEARKNWL
Sbjct: 606  NGWSIKYYKGLGTSTSKEGKEYFQDIDKHKKDFVWVDEQDGDAIDLAFSKKKIEARKNWL 665

Query: 540  RQFEAGTYLDHKEEEIKYSDFVNKELILFSRADLQRSIPSMVDGLKPGQRKILFCAFKRN 719
            RQFE GTYLD + ++IKYSDFVNKELILFS ADLQRSIPSMVDGLKPGQRKILFC+FKRN
Sbjct: 666  RQFEPGTYLDQRMKKIKYSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKILFCSFKRN 725

Query: 720  LIKEAKVAQFSGYVSEHSAYHHGEQSLASTIVGMAQDFVGSNNINLFQPKGQFGTRNKGG 899
             +KEAKVAQFSGYVSEHSAYHHGEQSLASTI+GMAQDFVGSNNINL QP GQFGTRN+GG
Sbjct: 726  FVKEAKVAQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLQPNGQFGTRNQGG 785

Query: 900  KDAASGRYIYTCLSPITRFLFPKXXXXXXXXXXXXGQSIEPAWYMPIIPMVLVNGSEGIG 1079
            KD AS RYIYT LSP+TRFLFPK            GQSIEP WY+PIIPMVL+NGSEGIG
Sbjct: 786  KDHASARYIYTSLSPLTRFLFPKDDDILLDYLNEDGQSIEPTWYIPIIPMVLINGSEGIG 845

Query: 1080 TGWSSYVPNYNPRDVVANVRRLLNDEPMRPMEPWYRGFKGLIEKSAQKETGVTYTISGII 1259
            TGWSS+VPNYNPRD++ANVRRLLNDEPM+PM+PWYRGFKGLIEKSA KE GVTYTI+GII
Sbjct: 846  TGWSSFVPNYNPRDIIANVRRLLNDEPMQPMDPWYRGFKGLIEKSATKEAGVTYTITGII 905

Query: 1260 EEVDITTLRITELPIRSWTADYNEFLDAMMKGTDKFKEPFIQDKRAYNDDVIVHFEVILS 1439
            EEVD  TLRI ELP+R WT DY EFL+A+M G DK KEPFI+D R +NDD  VHFEV L+
Sbjct: 906  EEVDNATLRIMELPVRRWTQDYKEFLEALMTGNDKVKEPFIKDYREHNDDTTVHFEVTLT 965

Query: 1440 EENMMAAKQEGXXXXXXXXXXISTSNMHLFDSNGTIKKYDTPEQILEDFFHLRLQFYEKR 1619
            EEN+  A QEG          I T+NMHLFDSNG IKKYDTPEQILEDFFHLRL+FYEKR
Sbjct: 966  EENLNIALQEGLEKKFKLTTTIGTTNMHLFDSNGVIKKYDTPEQILEDFFHLRLEFYEKR 1025

Query: 1620 KKVXXXXXXXXXXXXXXXVRFILAVVKGEIIVNNRRRADLFLELHQKGFTPFPKKTKGID 1799
            KKV               VRFIL VV+GEIIVNNR+RA+LF+ELHQKGFTPFPKK+KGID
Sbjct: 1026 KKVLLDNLEMDLLKLDNKVRFILGVVRGEIIVNNRKRAELFIELHQKGFTPFPKKSKGID 1085

Query: 1800 AAIAGATVDTXXXXXXXXXTVKGVVKASDYEYLLSMSIGSLTLEKVQELCADKQKLDHEL 1979
             AI GAT +            KG V+ASDYEYLLSM+IG+LTLEKVQELC ++ KL+ E+
Sbjct: 1086 VAIVGATTEEEENEESPEMG-KGGVRASDYEYLLSMAIGTLTLEKVQELCGERDKLESEV 1144

Query: 1980 EELRSTSSKILWMRDLDALEKQLDELDQKDVEAANMQEKIRRRNTGAAVPSK-APKKPRK 2156
            EELR  + + LW++DLDALE++L+E ++KD EA   +  +R +N GAA  SK   KKPRK
Sbjct: 1145 EELRKATPRSLWLKDLDALERELEEQERKDAEADGARRAMRAKNIGAAAASKQGAKKPRK 1204

Query: 2157 NNAIKGPTVAANDADVGTTSTAMDAGNXXXXXXXXXXXXXXXDAAKKTTVVXXXXXXXXX 2336
            N A K  T    D            GN                 AK   V          
Sbjct: 1205 NTANKASTTTLEDT---------SNGNIPEPSKPKPRGPPKKAPAKSKAVESDDEDEVLE 1255

Query: 2337 XKDRLAAYNLDSSPDQTFMETESVAQEVLKMKAPSKRATVRKGKSTMTILXXXXXXXXXX 2516
             K+RLAAYNL+SSPD + ME E +  +V   K PSK A  RK  + +T L          
Sbjct: 1256 LKERLAAYNLNSSPDHSTMEIEGLVSQVEPEKEPSKGAAARKAPAAITHL-SDEDGDDDQ 1314

Query: 2517 XPAISEDGDDGDFQMVEVXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXQGKSLVSQKLI 2696
             P I E  DD +F+++E                                Q K  ++QKLI
Sbjct: 1315 MPTILEGNDDDEFELLEEAAPKEKKPARGRKPAGDKLKAAVGTRKRGPAQNKPALTQKLI 1374

Query: 2697 TDVLKPVVN---ASPEKKVRKMRESPFNKKSGSVLGRARGPVVESEGSIDSSPSVNLEVE 2867
            T VLKP      ASP+KKVRKMR SPFNKKSG++LG     ++ S  S + S     E  
Sbjct: 1375 TQVLKPSEKAKIASPKKKVRKMRASPFNKKSGTLLGNR---ILSSSASSEDSGGHASEGS 1431

Query: 2868 MNEVPVARNRPKRENRSKVQYV 2933
              E     NRPKR N  +  Y+
Sbjct: 1432 SAEAIAPVNRPKRNNIQRAVYI 1453


>ref|XP_010241213.1| PREDICTED: DNA topoisomerase 2-like isoform X1 [Nelumbo nucifera]
          Length = 1504

 Score = 1167 bits (3018), Expect = 0.0
 Identities = 621/1009 (61%), Positives = 709/1009 (70%), Gaps = 32/1009 (3%)
 Frame = +3

Query: 3    KGKLLNVREASLKQIMQNAEIQNIKQILGLQHGKQYDSVKGLRYGSLMIMTDQDHDGSHI 182
            +GKLLNVREA+ KQIM NAEIQNIKQILGLQHGK+YDSVK LRYG LMIMTDQDHDGSHI
Sbjct: 486  RGKLLNVREATHKQIMDNAEIQNIKQILGLQHGKEYDSVKSLRYGHLMIMTDQDHDGSHI 545

Query: 183  KGLLINFIHSFWPSLLKVKGFMVEFITPIVKASHKNGTVLSFYTMPEYEAWKESLNGNAT 362
            KGLLINFIHSFWPSLLK+  F+VEFITPIVKA+HKNG VLSFY+MPEYE+WK  L GNA+
Sbjct: 546  KGLLINFIHSFWPSLLKIPSFLVEFITPIVKATHKNGKVLSFYSMPEYESWKX-LGGNAS 604

Query: 363  GWTIKYYKGLGTSTAKEGKEYFKQLRKHKKSFVWADEQDGESIELAFSKKKIEARKNWLR 542
            GW+IKYYKGLGTST+KEGKEYFK L KHKK F+W D++DG++IELAFSKKKIEARKNWLR
Sbjct: 605  GWSIKYYKGLGTSTSKEGKEYFKDLHKHKKDFLWVDDRDGDAIELAFSKKKIEARKNWLR 664

Query: 543  QFEAGTYLDHKEEEIKYSDFVNKELILFSRADLQRSIPSMVDGLKPGQRKILFCAFKRNL 722
            QFE GT LD KE+ IKYSDFVNKELILFS ADLQRSIPSMVDGLKPGQRKILFCAFKRNL
Sbjct: 665  QFEPGTCLDQKEKLIKYSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKILFCAFKRNL 724

Query: 723  IKEAKVAQFSGYVSEHSAYHHGEQSLASTIVGMAQDFVGSNNINLFQPKGQFGTRNKGGK 902
            IKEAKVAQFSGYVSEHSAYHHGEQSL STI+GMAQD+VGSNNINLFQP GQFGTR++GGK
Sbjct: 725  IKEAKVAQFSGYVSEHSAYHHGEQSLMSTIIGMAQDYVGSNNINLFQPNGQFGTRHQGGK 784

Query: 903  DAASGRYIYTCLSPITRFLFPKXXXXXXXXXXXXGQSIEPAWYMPIIPMVLVNGSEGIGT 1082
            D AS RYIYT LSPITRFLFPK            GQSIEP WYMPIIP VLVNGSEGIGT
Sbjct: 785  DHASARYIYTRLSPITRFLFPKGDDILLDYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGT 844

Query: 1083 GWSSYVPNYNPRDVVANVRRLLNDEPMRPMEPWYRGFKGLIEKSAQKETGVTYTISGIIE 1262
            GWSSY+PNYNPRD+VAN++RLLN EPM PM+PWY+GFKGLIEK+A KE G +YT+SGIIE
Sbjct: 845  GWSSYIPNYNPRDIVANIKRLLNGEPMEPMDPWYKGFKGLIEKTATKEAGSSYTVSGIIE 904

Query: 1263 EVDITTLRITELPIRSWTADYNEFLDAMMKGTDKFKEPFIQDKRAYNDDVIVHFEVILSE 1442
            E++ TTLRITELPIR WT DY EFL+++M G DK KEPFI+D + +NDD  VHFE+ILSE
Sbjct: 905  EINETTLRITELPIRRWTQDYKEFLESIMTGNDKIKEPFIKDYKEHNDDTTVHFEIILSE 964

Query: 1443 ENMMAAKQEGXXXXXXXXXXISTSNMHLFDSNGTIKKYDTPEQILEDFFHLRLQFYEKRK 1622
            EN+M AKQEG          ISTSNMHLFD  GTIKKYD PEQILE+FFHLRL+FYEKRK
Sbjct: 965  ENLMMAKQEGLMKKFKLTTTISTSNMHLFDPKGTIKKYDNPEQILEEFFHLRLEFYEKRK 1024

Query: 1623 KVXXXXXXXXXXXXXXXVRFILAVVKGEIIVNNRRRADLFLELHQKGFTPFPKKTKGIDA 1802
            K                VRFIL VVKGEIIV+NR+R DLFLEL QKGFTPFPKKTK ++A
Sbjct: 1025 KTQLDNLELDLLKLDNKVRFILGVVKGEIIVSNRKRVDLFLELQQKGFTPFPKKTKALEA 1084

Query: 1803 AIAGATVDTXXXXXXXXXTVKGVVKASDYEYLLSMSIGSLTLEKVQELCADKQKLDHELE 1982
            A+AGA  D               V+ASDYEYLLSM+IG+LTLEKVQELC+D+ KL+HE+E
Sbjct: 1085 AVAGANEDGEENEENSEVVSSRGVRASDYEYLLSMAIGTLTLEKVQELCSDRDKLNHEVE 1144

Query: 1983 ELRSTSSKILWMRDLDALEKQLDELDQKDVEAANMQEKIRRR---NTGAAVPSKAPKKPR 2153
            ELR  +   LWM DLDALEK+LDE D+ D +A   +++++ R     G     +APK PR
Sbjct: 1145 ELRKATPNSLWMNDLDALEKELDEQDKNDAQAEEARKELKNRVMSEAGMKASRQAPKNPR 1204

Query: 2154 KNNAIKGPTVAANDADVGTTS--TAMDAGNXXXXXXXXXXXXXXXDAAKKTTV----VXX 2315
            K NA K  T       V  +S  +AM+                   A K+  +       
Sbjct: 1205 KTNAKKPSTSETVTESVAASSVGSAMETVPEVVKPKGRGGRPKKAPAKKQDNMRLVDSDE 1264

Query: 2316 XXXXXXXXKDRLAAYNLDSSPDQTFMETESVAQEVLKMKAPSKRATVRKGKSTMTILXXX 2495
                    K+RLAAYNLDSSP+Q+ +    VA+   K K PSKRA  +K  S+ T     
Sbjct: 1265 DDVDVIELKERLAAYNLDSSPEQSAVMETEVAKVPAKKKEPSKRAAAQKQPSSYT----- 1319

Query: 2496 XXXXXXXXPAISEDGDDGDFQMVEVXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXQGK- 2672
                      IS+D D  D Q +                                  GK 
Sbjct: 1320 ---------EISDDDDGMDVQTIREESIGEIVSDEDFEPEVEEAPKGGRGGRKPAANGKA 1370

Query: 2673 --------------SLVSQKLITDVLKPVVNA--SPEKKVRKMRESPFNKKSGSVLGRAR 2804
                          S++ QK ITD+LKP  NA  SPEKKVRKMR SPFNKKSGSVLGR  
Sbjct: 1371 AASTKKRGAANKQTSVLGQKKITDLLKPAENAGVSPEKKVRKMRASPFNKKSGSVLGRVG 1430

Query: 2805 G------PVVESEGSIDSSPSVNLEVEMNEVPVARNRPKRENRSKVQYV 2933
            G      P+   E    +S +     E++EV  AR RP+R NR K +YV
Sbjct: 1431 GMVGDISPMGSEEQQTGTSSASTDSAELSEVVPARPRPQRVNRGKAKYV 1479


>ref|XP_010241214.1| PREDICTED: DNA topoisomerase 2-like isoform X2 [Nelumbo nucifera]
          Length = 1503

 Score = 1166 bits (3016), Expect = 0.0
 Identities = 621/1008 (61%), Positives = 708/1008 (70%), Gaps = 31/1008 (3%)
 Frame = +3

Query: 3    KGKLLNVREASLKQIMQNAEIQNIKQILGLQHGKQYDSVKGLRYGSLMIMTDQDHDGSHI 182
            +GKLLNVREA+ KQIM NAEIQNIKQILGLQHGK+YDSVK LRYG LMIMTDQDHDGSHI
Sbjct: 486  RGKLLNVREATHKQIMDNAEIQNIKQILGLQHGKEYDSVKSLRYGHLMIMTDQDHDGSHI 545

Query: 183  KGLLINFIHSFWPSLLKVKGFMVEFITPIVKASHKNGTVLSFYTMPEYEAWKESLNGNAT 362
            KGLLINFIHSFWPSLLK+  F+VEFITPIVKA+HKNG VLSFY+MPEYE+WK  L GNA+
Sbjct: 546  KGLLINFIHSFWPSLLKIPSFLVEFITPIVKATHKNGKVLSFYSMPEYESWKX-LGGNAS 604

Query: 363  GWTIKYYKGLGTSTAKEGKEYFKQLRKHKKSFVWADEQDGESIELAFSKKKIEARKNWLR 542
            GW+IKYYKGLGTST+KEGKEYFK L KHKK F+W D++DG++IELAFSKKKIEARKNWLR
Sbjct: 605  GWSIKYYKGLGTSTSKEGKEYFKDLHKHKKDFLWVDDRDGDAIELAFSKKKIEARKNWLR 664

Query: 543  QFEAGTYLDHKEEEIKYSDFVNKELILFSRADLQRSIPSMVDGLKPGQRKILFCAFKRNL 722
            QFE GT LD KE+ IKYSDFVNKELILFS ADLQRSIPSMVDGLKPGQRKILFCAFKRNL
Sbjct: 665  QFEPGTCLDQKEKLIKYSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKILFCAFKRNL 724

Query: 723  IKEAKVAQFSGYVSEHSAYHHGEQSLASTIVGMAQDFVGSNNINLFQPKGQFGTRNKGGK 902
            IKEAKVAQFSGYVSEHSAYHHGEQSL STI+GMAQD+VGSNNINLFQP GQFGTR++GGK
Sbjct: 725  IKEAKVAQFSGYVSEHSAYHHGEQSLMSTIIGMAQDYVGSNNINLFQPNGQFGTRHQGGK 784

Query: 903  DAASGRYIYTCLSPITRFLFPKXXXXXXXXXXXXGQSIEPAWYMPIIPMVLVNGSEGIGT 1082
            D AS RYIYT LSPITRFLFPK            GQSIEP WYMPIIP VLVNGSEGIGT
Sbjct: 785  DHASARYIYTRLSPITRFLFPKGDDILLDYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGT 844

Query: 1083 GWSSYVPNYNPRDVVANVRRLLNDEPMRPMEPWYRGFKGLIEKSAQKETGVTYTISGIIE 1262
            GWSSY+PNYNPRD+VAN++RLLN EPM PM+PWY+GFKGLIEK+A KE G +YT+SGIIE
Sbjct: 845  GWSSYIPNYNPRDIVANIKRLLNGEPMEPMDPWYKGFKGLIEKTATKEAGSSYTVSGIIE 904

Query: 1263 EVDITTLRITELPIRSWTADYNEFLDAMMKGTDKFKEPFIQDKRAYNDDVIVHFEVILSE 1442
            E++ TTLRITELPIR WT DY EFL+++M G DK KEPFI+D + +NDD  VHFE+ILSE
Sbjct: 905  EINETTLRITELPIRRWTQDYKEFLESIMTGNDKIKEPFIKDYKEHNDDTTVHFEIILSE 964

Query: 1443 ENMMAAKQEGXXXXXXXXXXISTSNMHLFDSNGTIKKYDTPEQILEDFFHLRLQFYEKRK 1622
            EN+M AKQEG          ISTSNMHLFD  GTIKKYD PEQILE+FFHLRL+FYEKRK
Sbjct: 965  ENLMMAKQEGLMKKFKLTTTISTSNMHLFDPKGTIKKYDNPEQILEEFFHLRLEFYEKRK 1024

Query: 1623 KVXXXXXXXXXXXXXXXVRFILAVVKGEIIVNNRRRADLFLELHQKGFTPFPKKTKGIDA 1802
            K                VRFIL VVKGEIIV+NR+R DLFLEL QKGFTPFPKKTK ++A
Sbjct: 1025 KTQLDNLELDLLKLDNKVRFILGVVKGEIIVSNRKRVDLFLELQQKGFTPFPKKTKALEA 1084

Query: 1803 AIAGATVDTXXXXXXXXXTVKGVVKASDYEYLLSMSIGSLTLEKVQELCADKQKLDHELE 1982
            A+AGA  D               V+ASDYEYLLSM+IG+LTLEKVQELC+D+ KL+HE+E
Sbjct: 1085 AVAGANEDGEENEENSEVVSSRGVRASDYEYLLSMAIGTLTLEKVQELCSDRDKLNHEVE 1144

Query: 1983 ELRSTSSKILWMRDLDALEKQLDELDQKDVEAANMQEKIRRR---NTGAAVPSKAPKKPR 2153
            ELR  +   LWM DLDALEK+LDE D+ D +A   +++++ R     G     +APK PR
Sbjct: 1145 ELRKATPNSLWMNDLDALEKELDEQDKNDAQAEEARKELKNRVMSEAGMKASRQAPKNPR 1204

Query: 2154 KNNAIKGPTVAANDADVGTTS--TAMDAGNXXXXXXXXXXXXXXXDAAK---KTTVVXXX 2318
            K NA K  T       V  +S  +AM+                   A K   +       
Sbjct: 1205 KTNAKKPSTSETVTESVAASSVGSAMETVPEVVKPKGRGGRPKKAPAKKDNMRLVDSDED 1264

Query: 2319 XXXXXXXKDRLAAYNLDSSPDQTFMETESVAQEVLKMKAPSKRATVRKGKSTMTILXXXX 2498
                   K+RLAAYNLDSSP+Q+ +    VA+   K K PSKRA  +K  S+ T      
Sbjct: 1265 DVDVIELKERLAAYNLDSSPEQSAVMETEVAKVPAKKKEPSKRAAAQKQPSSYT------ 1318

Query: 2499 XXXXXXXPAISEDGDDGDFQMVEVXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXQGK-- 2672
                     IS+D D  D Q +                                  GK  
Sbjct: 1319 --------EISDDDDGMDVQTIREESIGEIVSDEDFEPEVEEAPKGGRGGRKPAANGKAA 1370

Query: 2673 -------------SLVSQKLITDVLKPVVNA--SPEKKVRKMRESPFNKKSGSVLGRARG 2807
                         S++ QK ITD+LKP  NA  SPEKKVRKMR SPFNKKSGSVLGR  G
Sbjct: 1371 ASTKKRGAANKQTSVLGQKKITDLLKPAENAGVSPEKKVRKMRASPFNKKSGSVLGRVGG 1430

Query: 2808 ------PVVESEGSIDSSPSVNLEVEMNEVPVARNRPKRENRSKVQYV 2933
                  P+   E    +S +     E++EV  AR RP+R NR K +YV
Sbjct: 1431 MVGDISPMGSEEQQTGTSSASTDSAELSEVVPARPRPQRVNRGKAKYV 1478


>ref|XP_020703085.1| DNA topoisomerase 2-like [Dendrobium catenatum]
 gb|PKU64218.1| DNA topoisomerase 2 [Dendrobium catenatum]
          Length = 1268

 Score = 1160 bits (3000), Expect = 0.0
 Identities = 606/981 (61%), Positives = 715/981 (72%), Gaps = 4/981 (0%)
 Frame = +3

Query: 3    KGKLLNVREASLKQIMQNAEIQNIKQILGLQHGKQYDSVKGLRYGSLMIMTDQDHDGSHI 182
            +GKLLNVREAS KQIM+NAEIQNIKQILGLQ GKQY+SVKGLRYG LMIMTDQDHDGSHI
Sbjct: 290  RGKLLNVREASHKQIMENAEIQNIKQILGLQQGKQYESVKGLRYGHLMIMTDQDHDGSHI 349

Query: 183  KGLLINFIHSFWPSLLKVKGFMVEFITPIVKASHKNGTVLSFYTMPEYEAWKESLNGNAT 362
            KGLLINFIHSFWPSLLK+  F+VEFITPIVKA+++ G VLSFYTMPEYE+WKESL GNA+
Sbjct: 350  KGLLINFIHSFWPSLLKIPSFLVEFITPIVKATYRTGKVLSFYTMPEYESWKESLRGNAS 409

Query: 363  GWTIKYYKGLGTSTAKEGKEYFKQLRKHKKSFVWADEQDGESIELAFSKKKIEARKNWLR 542
            GW+IKYYKGLGTST+KEGKEYF+ L+KHKK FVW DEQDGE+IELAFSKKKIEARKNWLR
Sbjct: 410  GWSIKYYKGLGTSTSKEGKEYFQDLQKHKKDFVWFDEQDGEAIELAFSKKKIEARKNWLR 469

Query: 543  QFEAGTYLDHKEEEIKYSDFVNKELILFSRADLQRSIPSMVDGLKPGQRKILFCAFKRNL 722
            QFE GTYLD  E+ I YSDFVNKELILFS ADLQRSIPSM+DGLKPGQRKILFC+FKRN 
Sbjct: 470  QFEPGTYLDQNEKLISYSDFVNKELILFSMADLQRSIPSMLDGLKPGQRKILFCSFKRNF 529

Query: 723  IKEAKVAQFSGYVSEHSAYHHGEQSLASTIVGMAQDFVGSNNINLFQPKGQFGTRNKGGK 902
            +KEAK++QFSGYVSEHSAYHHGEQSLASTI+GMAQDFVGSNNINL QP GQFGTR++GGK
Sbjct: 530  VKEAKISQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLQPNGQFGTRHQGGK 589

Query: 903  DAASGRYIYTCLSPITRFLFPKXXXXXXXXXXXXGQSIEPAWYMPIIPMVLVNGSEGIGT 1082
            D AS RYIYT LSP+TRFLFPK            GQSIEPAWY+PIIPMVLVNGSEGIGT
Sbjct: 590  DHASARYIYTKLSPMTRFLFPKEDDLILDYMSEDGQSIEPAWYVPIIPMVLVNGSEGIGT 649

Query: 1083 GWSSYVPNYNPRDVVANVRRLLNDEPMRPMEPWYRGFKGLIEKSAQKETGVTYTISGIIE 1262
            GWSSY+PNYNPRD+V NVRRLLNDEPM PM+PWYRGFKGLIEK+A KE G TYT++GIIE
Sbjct: 650  GWSSYIPNYNPRDIVKNVRRLLNDEPMLPMDPWYRGFKGLIEKTAVKEAGATYTVTGIIE 709

Query: 1263 EVDITTLRITELPIRSWTADYNEFLDAMMKGTDKFKEPFIQDKRAYNDDVIVHFEVILSE 1442
            E D  TL ITELP+R WT DY EFL++++ GTDK K+PFI+D R YNDD  VHFEV LSE
Sbjct: 710  ESDSNTLTITELPVRRWTQDYKEFLESLVTGTDKVKDPFIKDYREYNDDTTVHFEVTLSE 769

Query: 1443 ENMMAAKQEGXXXXXXXXXXISTSNMHLFDSNGTIKKYDTPEQILEDFFHLRLQFYEKRK 1622
            +N++ AKQEG          ISTSNMHLFD  G IKKYDTPEQILE+FFHLR+ +YEKRK
Sbjct: 770  QNLIMAKQEGLEKKFKLSTTISTSNMHLFDHKGVIKKYDTPEQILEEFFHLRITYYEKRK 829

Query: 1623 KVXXXXXXXXXXXXXXXVRFILAVVKGEIIVNNRRRADLFLELHQKGFTPFPKKTKGIDA 1802
            K                VRFIL VVKG+IIVNNR+RA+LFLEL +KGFTPFPKKTKG+D 
Sbjct: 830  KALLDNLELDLLKLDNKVRFILGVVKGQIIVNNRKRAELFLELQEKGFTPFPKKTKGVDV 889

Query: 1803 AIAGATVDTXXXXXXXXXTVKGVVKASDYEYLLSMSIGSLTLEKVQELCADKQKLDHELE 1982
            AIAGAT +T           KG VK SDY+YLLSM+IG+LT EKVQELCA+K+K +++++
Sbjct: 890  AIAGATPET-EESEETTEVAKGGVKPSDYDYLLSMAIGTLTWEKVQELCAEKEKFENDVK 948

Query: 1983 ELRSTSSKILWMRDLDALEKQLDELDQKDVEAANMQEKIRRR--NTGAAVPSKAPKKPRK 2156
            ELR ++   LW++DLDAL+K+LD L+++D EA  M++KI+ +  N GAA   +APKKPRK
Sbjct: 949  ELRGSTPSSLWIKDLDALDKELDNLERQDAEAEVMRKKIKAKAGNGGAAAAKQAPKKPRK 1008

Query: 2157 NNAIKGPTVAANDADVGTTSTAMDAGNXXXXXXXXXXXXXXXDAAKKTTVVXXXXXXXXX 2336
            NN    P+ A       T   A+D+                   ++  +V          
Sbjct: 1009 NNT--KPSAA-------TEPIAIDSETVQEVTKNKPKGRQNKSKSQPVSVESDEDEDLIA 1059

Query: 2337 XKDRLAAYNLDSSPDQTFMETESVAQEVLKMKAPSKRATVRKGKSTMTILXXXXXXXXXX 2516
             K+RL AYNLDSSP++  METE++ +     + P KRA     +  MT++          
Sbjct: 1060 LKERLEAYNLDSSPERLAMETETMPEAAAAKEGPKKRAAA--ARKAMTVVS--------- 1108

Query: 2517 XPAISEDGDDGDFQMVEVXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXQGKSLVSQKLI 2696
                 ED DD DF+  +V                               Q K +++QKLI
Sbjct: 1109 ----DEDTDDEDFENSKV-PKGKKGAGGGRKPANATKAKATIAAKKREGQIKPILAQKLI 1163

Query: 2697 TDVLKPVVNA--SPEKKVRKMRESPFNKKSGSVLGRARGPVVESEGSIDSSPSVNLEVEM 2870
            +++L P  NA  SPEKKVRK+R SPFNKKSGS L ++    +    S +SS   + E + 
Sbjct: 1164 SELLPPATNAVDSPEKKVRKIRPSPFNKKSGSFLDKSG---INGSSSENSSLGASDEAQ- 1219

Query: 2871 NEVPVARNRPKRENRSKVQYV 2933
             E   A+ RPKRENR++  YV
Sbjct: 1220 REDSAAKARPKRENRTRAVYV 1240


>ref|XP_009399445.1| PREDICTED: DNA topoisomerase 2-like [Musa acuminata subsp.
            malaccensis]
          Length = 1466

 Score = 1158 bits (2995), Expect = 0.0
 Identities = 616/981 (62%), Positives = 700/981 (71%), Gaps = 4/981 (0%)
 Frame = +3

Query: 3    KGKLLNVREASLKQIMQNAEIQNIKQILGLQHGKQYDSVKGLRYGSLMIMTDQDHDGSHI 182
            +GKLLNVREA+ KQI+ NAEIQNIKQILGLQHGK+YDS KGLRYG LMIMTDQDHDGSHI
Sbjct: 486  RGKLLNVREANHKQILDNAEIQNIKQILGLQHGKEYDSAKGLRYGHLMIMTDQDHDGSHI 545

Query: 183  KGLLINFIHSFWPSLLKVKGFMVEFITPIVKASH-KNGTVLSFYTMPEYEAWKESLNGNA 359
            KGLLINFIH+FWPSLLKV  FMVEFITP++KA++ KN TVLSFY+MPEYEAWKESL GNA
Sbjct: 546  KGLLINFIHTFWPSLLKVPSFMVEFITPLLKATNNKNKTVLSFYSMPEYEAWKESLGGNA 605

Query: 360  TGWTIKYYKGLGTSTAKEGKEYFKQLRKHKKSFVWADEQDGESIELAFSKKKIEARKNWL 539
             GW+IKYYKGLGTS ++EGK+YFK + KHKK FVW DEQDG++IELAFSKKKIEARKNWL
Sbjct: 606  NGWSIKYYKGLGTSKSEEGKDYFKAIDKHKKDFVWVDEQDGDAIELAFSKKKIEARKNWL 665

Query: 540  RQFEAGTYLDHKEEEIKYSDFVNKELILFSRADLQRSIPSMVDGLKPGQRKILFCAFKRN 719
            RQFE   YLD +E+ IKYSDF+NKELILFSRADLQRSIPSMVDGLKPGQRKILFCAFKRN
Sbjct: 666  RQFEPENYLDQREKLIKYSDFINKELILFSRADLQRSIPSMVDGLKPGQRKILFCAFKRN 725

Query: 720  LIKEAKVAQFSGYVSEHSAYHHGEQSLASTIVGMAQDFVGSNNINLFQPKGQFGTRNKGG 899
             +K+AKVAQF GYVSE SAYHHGEQSLA+TI+GMAQDFVGSNNINL QP+GQFGTR++GG
Sbjct: 726  FVKQAKVAQFVGYVSEKSAYHHGEQSLATTIIGMAQDFVGSNNINLLQPEGQFGTRHQGG 785

Query: 900  KDAASGRYIYTCLSPITRFLFPKXXXXXXXXXXXXGQSIEPAWYMPIIPMVLVNGSEGIG 1079
            KD AS RYI+TCLSPITRFLFPK            GQSIEP WYMPIIPMVL NGSEGIG
Sbjct: 786  KDHASARYIFTCLSPITRFLFPKDDDILLDYLNEDGQSIEPTWYMPIIPMVLANGSEGIG 845

Query: 1080 TGWSSYVPNYNPRDVVANVRRLLNDEPMRPMEPWYRGFKGLIEKSAQKETGVTYTISGII 1259
            TGWSSY+PNYNP+D+VANVRRLLN+EPM+PM+PWYRGF G IEKSA KE GVTYTI+G I
Sbjct: 846  TGWSSYIPNYNPKDIVANVRRLLNNEPMQPMDPWYRGFTGRIEKSATKEAGVTYTITGAI 905

Query: 1260 EEVDITTLRITELPIRSWTADYNEFLDAMMKGTDKFKEPFIQDKRAYNDDVIVHFEVILS 1439
            EEV+ TTLRITELPIR WT DY EFL++MM G DK KEPFI+D R YNDD  VHFEV L+
Sbjct: 906  EEVNGTTLRITELPIRRWTQDYKEFLESMMTGNDKSKEPFIKDYREYNDDKTVHFEVTLT 965

Query: 1440 EENMMAAKQEGXXXXXXXXXXISTSNMHLFDSNGTIKKYDTPEQILEDFFHLRLQFYEKR 1619
            E+N+  A+QEG          I T+NMHLFD  G IKKYD  EQILE+FFHLR +FYEKR
Sbjct: 966  EDNLSIARQEGLEKKFKLTTSIGTTNMHLFDPKGVIKKYDNSEQILEEFFHLRYEFYEKR 1025

Query: 1620 KKVXXXXXXXXXXXXXXXVRFILAVVKGEIIVNNRRRADLFLELHQKGFTPFPKKTKGID 1799
            KK                VRFIL VV+GEIIVNNR+RADLFLEL QKGF P PKKTKGID
Sbjct: 1026 KKALLDNLEFQLLKLDNKVRFILGVVRGEIIVNNRKRADLFLELQQKGFAPMPKKTKGID 1085

Query: 1800 AAIAGATVDTXXXXXXXXXTVKGVVKASDYEYLLSMSIGSLTLEKVQELCADKQKLDHEL 1979
            AA      +            +G VKASDYEYL+SM IG+LTLEKVQELCA+K KL+ E+
Sbjct: 1086 AAATEEEEEDEQEEESPEAGKRG-VKASDYEYLMSMPIGTLTLEKVQELCAEKDKLEGEV 1144

Query: 1980 EELRSTSSKILWMRDLDALEKQLDELDQKDVEAANMQEKIRRRNTGAAVPSK-APKKPRK 2156
            +ELR TS + LW+++LDALE++LD+L++KD EA    E+IR +N   AVPS+ APKKPRK
Sbjct: 1145 DELRRTSPRSLWLKELDALEEELDKLERKDAEA----EEIRMKNNAGAVPSRQAPKKPRK 1200

Query: 2157 NNAIKGPTVAANDADVGTTSTAMDAGNXXXXXXXXXXXXXXXDAAKKTTVVXXXXXXXXX 2336
                     A+N +  G   T  DAG                   K T +          
Sbjct: 1201 K--------ASNKSVTGPEKTVTDAGQ-----KKTNGGSKRAPVKKNTVIESDEDDDIDD 1247

Query: 2337 XKDRLAAYNLDSSPDQTFMETESVAQEVLKMKAPSKRATVRKGKSTMTILXXXXXXXXXX 2516
             KDRLAAYNLDSSPDQT MET+SV  E    +      T    K+T T+L          
Sbjct: 1248 LKDRLAAYNLDSSPDQTVMETDSVVVEQQGGQKKQASRTAAARKATHTVLSDNEDDEAQN 1307

Query: 2517 XPAISEDGDDGDFQMVEVXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXQGKSLVSQKLI 2696
                 E+  D DF +VE                                  K ++SQKLI
Sbjct: 1308 YMPTIEEDKDKDFNLVE---PKGRKVRGRKPANEKAKPATTTRKRGPAQSSKPVLSQKLI 1364

Query: 2697 TDVLKPVVNA--SPEKKVRKMRESPFNKKSGSVLGRARGPVVESEGSIDSSPSVNLEVEM 2870
            T+VLKP  N   SPEKK+RKMR+SPFNK+SGSVLGR       SE S   SPS   E   
Sbjct: 1365 TEVLKPAENGGNSPEKKMRKMRDSPFNKRSGSVLGRPTSSPSGSEDSNGLSPSGPAET-T 1423

Query: 2871 NEVPVARNRPKRENRSKVQYV 2933
            N V  AR RPKREN +K  YV
Sbjct: 1424 NVVAAARTRPKRENMTKAVYV 1444


>ref|XP_020693654.1| DNA topoisomerase 2 [Dendrobium catenatum]
 gb|PKU72193.1| DNA topoisomerase 2 [Dendrobium catenatum]
          Length = 1466

 Score = 1155 bits (2989), Expect = 0.0
 Identities = 605/981 (61%), Positives = 715/981 (72%), Gaps = 4/981 (0%)
 Frame = +3

Query: 3    KGKLLNVREASLKQIMQNAEIQNIKQILGLQHGKQYDSVKGLRYGSLMIMTDQDHDGSHI 182
            +GKLLNVREAS KQIM+NAEIQNIKQILGLQ GK+Y+SVKGLRYG LMIMTDQDHDGSHI
Sbjct: 488  RGKLLNVREASHKQIMENAEIQNIKQILGLQQGKEYESVKGLRYGHLMIMTDQDHDGSHI 547

Query: 183  KGLLINFIHSFWPSLLKVKGFMVEFITPIVKASHKNGTVLSFYTMPEYEAWKESLNGNAT 362
            KGLLINFIHSFWPSLLK+  F+VEFITPIVKA+++ G VLSFYTMPEYE+WKESL GNA+
Sbjct: 548  KGLLINFIHSFWPSLLKIPSFLVEFITPIVKATYRTGKVLSFYTMPEYESWKESLGGNAS 607

Query: 363  GWTIKYYKGLGTSTAKEGKEYFKQLRKHKKSFVWADEQDGESIELAFSKKKIEARKNWLR 542
            GW+IKYYKGLGTST+KEGKEYF+ L+KHKK FVW DEQDGE+IELAFSKKKIEARKNWLR
Sbjct: 608  GWSIKYYKGLGTSTSKEGKEYFQDLQKHKKDFVWFDEQDGEAIELAFSKKKIEARKNWLR 667

Query: 543  QFEAGTYLDHKEEEIKYSDFVNKELILFSRADLQRSIPSMVDGLKPGQRKILFCAFKRNL 722
            QFE GTYLD  E+ I YSDFVNKELILFS ADLQRSIPSMVDGLKPGQRKILFC+FKRN 
Sbjct: 668  QFEPGTYLDQNEKLISYSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKILFCSFKRNF 727

Query: 723  IKEAKVAQFSGYVSEHSAYHHGEQSLASTIVGMAQDFVGSNNINLFQPKGQFGTRNKGGK 902
            +KEAK++QFSGYVSEHSAYHHGEQSLASTI+GMAQDFVGSNNINL QP GQFGTR++GGK
Sbjct: 728  VKEAKISQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLQPNGQFGTRHQGGK 787

Query: 903  DAASGRYIYTCLSPITRFLFPKXXXXXXXXXXXXGQSIEPAWYMPIIPMVLVNGSEGIGT 1082
            D AS RYIYT LSP+TRFLFPK            GQSIEPAWY+PIIPMVLVNGSEGIGT
Sbjct: 788  DHASARYIYTKLSPMTRFLFPKEDDLILDYMSEDGQSIEPAWYVPIIPMVLVNGSEGIGT 847

Query: 1083 GWSSYVPNYNPRDVVANVRRLLNDEPMRPMEPWYRGFKGLIEKSAQKETGVTYTISGIIE 1262
            GWSSY+PNYNPRD+V N+RRLLNDEPM PM+PWYRGFKGLIEK+A KE   TYT++GIIE
Sbjct: 848  GWSSYIPNYNPRDIVKNLRRLLNDEPMLPMDPWYRGFKGLIEKTAVKEACATYTVTGIIE 907

Query: 1263 EVDITTLRITELPIRSWTADYNEFLDAMMKGTDKFKEPFIQDKRAYNDDVIVHFEVILSE 1442
            E D  TL ITELP+R WT DY EFL++++ GTDK KEPFI+D R YNDD  VHFEV LS+
Sbjct: 908  ESDSNTLTITELPVRRWTQDYKEFLESLVTGTDKVKEPFIKDYREYNDDTTVHFEVTLSD 967

Query: 1443 ENMMAAKQEGXXXXXXXXXXISTSNMHLFDSNGTIKKYDTPEQILEDFFHLRLQFYEKRK 1622
            +N++ AKQEG          ISTSNMHLFD  G IKKYDTPEQILE+FFHLR+ +YEKRK
Sbjct: 968  QNLIMAKQEGLEKKFKLSTTISTSNMHLFDHKGVIKKYDTPEQILEEFFHLRITYYEKRK 1027

Query: 1623 KVXXXXXXXXXXXXXXXVRFILAVVKGEIIVNNRRRADLFLELHQKGFTPFPKKTKGIDA 1802
            K                VRFIL VVKG+IIVNNR+RA+LFLEL +KGFTPFPKKTKG+D 
Sbjct: 1028 KALLDNLELDLLKLDNKVRFILGVVKGQIIVNNRKRAELFLELQEKGFTPFPKKTKGVDV 1087

Query: 1803 AIAGATVDTXXXXXXXXXTVKGVVKASDYEYLLSMSIGSLTLEKVQELCADKQKLDHELE 1982
            AIAGAT +T          VKG VK SDY+YLLS++IG+LT EKVQELC++K+K +++++
Sbjct: 1088 AIAGATPET-EESEETTEVVKGGVKPSDYDYLLSLAIGTLTWEKVQELCSEKEKFENDVK 1146

Query: 1983 ELRSTSSKILWMRDLDALEKQLDELDQKDVEAANMQEKIRRR--NTGAAVPSKAPKKPRK 2156
            ELR +S   LW++DLDAL+K+LD L+++D EA   ++KI+ +  N GAA   +APKKPRK
Sbjct: 1147 ELRGSSPSSLWIKDLDALDKELDNLERQDAEAEVTRKKIKAKAGNGGAAAAKQAPKKPRK 1206

Query: 2157 NNAIKGPTVAANDADVGTTSTAMDAGNXXXXXXXXXXXXXXXDAAKKTTVVXXXXXXXXX 2336
            NN    P+ A       T   A+D+                   ++  +V          
Sbjct: 1207 NNT--KPSAA-------TEPIAIDSETVQEVTKNKPKRLQNKSKSQPVSVESDEDEDLVA 1257

Query: 2337 XKDRLAAYNLDSSPDQTFMETESVAQEVLKMKAPSKRATVRKGKSTMTILXXXXXXXXXX 2516
             K+RL AYNLDSSP++  METE++ +     + P KRA     +  MT++          
Sbjct: 1258 LKERLEAYNLDSSPERLAMETETMPEAAAAKEGPKKRAAA--ARKAMTVVS--------- 1306

Query: 2517 XPAISEDGDDGDFQMVEVXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXQGKSLVSQKLI 2696
                 ED DD DF+  +V                               Q K L++QKLI
Sbjct: 1307 ----DEDTDDEDFENSKV-PKGKKGAGGGRKPANATKAKATITTKKREGQIKPLLAQKLI 1361

Query: 2697 TDVLKPVVNA--SPEKKVRKMRESPFNKKSGSVLGRARGPVVESEGSIDSSPSVNLEVEM 2870
            +++L P  NA  SPEKKVRK+R SPFNKKSGS L ++    +    S +SS   + E + 
Sbjct: 1362 SELLPPATNAVDSPEKKVRKIRPSPFNKKSGSFLDKSG---INGSSSENSSLGTSDEAQ- 1417

Query: 2871 NEVPVARNRPKRENRSKVQYV 2933
             E  VA+ RPKRENR++  YV
Sbjct: 1418 REDSVAKARPKRENRTRAVYV 1438


>ref|XP_009402954.1| PREDICTED: DNA topoisomerase 2-like [Musa acuminata subsp.
            malaccensis]
          Length = 1473

 Score = 1154 bits (2986), Expect = 0.0
 Identities = 616/991 (62%), Positives = 709/991 (71%), Gaps = 14/991 (1%)
 Frame = +3

Query: 3    KGKLLNVREASLKQIMQNAEIQNIKQILGLQHGKQYDSVKGLRYGSLMIMTDQDHDGSHI 182
            +GKLLNVREA+ KQIM NAEIQN+KQILGLQHGK+YDS KGLRYG LMIMTDQDHDGSHI
Sbjct: 492  RGKLLNVREANHKQIMDNAEIQNVKQILGLQHGKEYDSTKGLRYGHLMIMTDQDHDGSHI 551

Query: 183  KGLLINFIHSFWPSLLKVKGFMVEFITPIVKASH-KNGTVLSFYTMPEYEAWKESLNGNA 359
            KGLLINFIH+FWPSLLKV  FMVEFITP++KA++ KN TVLSFY+MPEYEAWKESL GN+
Sbjct: 552  KGLLINFIHTFWPSLLKVPSFMVEFITPLLKATNNKNKTVLSFYSMPEYEAWKESLGGNS 611

Query: 360  TGWTIKYYKGLGTSTAKEGKEYFKQLRKHKKSFVWADEQDGESIELAFSKKKIEARKNWL 539
            +GW+IKYYKGLGTS ++EGKEYFK + KHKK FVWADEQDG +IELAFSKKKIEARKNWL
Sbjct: 612  SGWSIKYYKGLGTSKSEEGKEYFKDIDKHKKEFVWADEQDGNAIELAFSKKKIEARKNWL 671

Query: 540  RQFEAGTYLDHKEEEIKYSDFVNKELILFSRADLQRSIPSMVDGLKPGQRKILFCAFKRN 719
            RQFE   YLD K++ IKYSDF+NKELILFSRADLQRSIPSMVDGLKPGQRKILFCAFKRN
Sbjct: 672  RQFEPDNYLDQKQKLIKYSDFINKELILFSRADLQRSIPSMVDGLKPGQRKILFCAFKRN 731

Query: 720  LIKEAKVAQFSGYVSEHSAYHHGEQSLASTIVGMAQDFVGSNNINLFQPKGQFGTRNKGG 899
             +K+AKVAQF GYVSE SAYHHGEQSL++TI+GMAQDFVGSNNINL  P+GQFGTR++GG
Sbjct: 732  FVKQAKVAQFVGYVSEKSAYHHGEQSLSTTIIGMAQDFVGSNNINLLLPEGQFGTRHQGG 791

Query: 900  KDAASGRYIYTCLSPITRFLFPKXXXXXXXXXXXXGQSIEPAWYMPIIPMVLVNGSEGIG 1079
            KD AS RYI+TC+SP+TRFLF K            GQSIEP WYMP+IP VLVNGSEGIG
Sbjct: 792  KDHASARYIFTCMSPVTRFLFSKDDDILLDYLNEDGQSIEPTWYMPVIPTVLVNGSEGIG 851

Query: 1080 TGWSSYVPNYNPRDVVANVRRLLNDEPMRPMEPWYRGFKGLIEKSAQKETGVTYTISGII 1259
            TGWSSYVPNYNP+D+VAN+RRLLNDEPM+PM+PWYRGFKG IEKSA KE GVTYTI+G+I
Sbjct: 852  TGWSSYVPNYNPKDIVANIRRLLNDEPMQPMDPWYRGFKGRIEKSATKEAGVTYTIAGVI 911

Query: 1260 EEVDITTLRITELPIRSWTADYNEFLDAMMKGTDKFKEPFIQDKRAYNDDVIVHFEVILS 1439
            EEVD TTLRITELP+R WT DY EFL++MM G DK KEPFI+D R YNDD  VHFEV L+
Sbjct: 912  EEVDNTTLRITELPVRRWTQDYKEFLESMMTGNDKIKEPFIKDYREYNDDKTVHFEVTLT 971

Query: 1440 EENMMAAKQEGXXXXXXXXXXISTSNMHLFDSNGTIKKYDTPEQILEDFFHLRLQFYEKR 1619
            EENM  A+QEG          I T+NMHLFDS G IKKYD PEQILE+FFH+R +FYEKR
Sbjct: 972  EENMNIARQEGLEKKFKLTTTIGTTNMHLFDSKGVIKKYDNPEQILEEFFHMRYEFYEKR 1031

Query: 1620 KKVXXXXXXXXXXXXXXXVRFILAVVKGEIIVNNRRRADLFLELHQKGFTPFPKKTKGID 1799
            KK                 RFIL VV+GEIIV+NR+RADLFLEL QKGFTP PKK KGID
Sbjct: 1032 KKALLDNLELDLLKLDNKARFILGVVRGEIIVSNRKRADLFLELQQKGFTPMPKKKKGID 1091

Query: 1800 AAIAGATVDTXXXXXXXXXTVKGVVKASDYEYLLSMSIGSLTLEKVQELCADKQKLDHEL 1979
            A +AGA  +            KG VKASDYEYL+ M IGSLTLEKVQELCADK +L+ E+
Sbjct: 1092 AVVAGAVEEEEDQEEESPEVGKGGVKASDYEYLMCMPIGSLTLEKVQELCADKDRLEGEV 1151

Query: 1980 EELRSTSSKILWMRDLDALEKQLDELDQKDVEAANMQEKIRRRNTGAAVPSK-APKKPRK 2156
            +ELR TS+K LW+++LDALE++LD+L++KD E   +++++R + T    PS+  PKKPRK
Sbjct: 1152 DELRRTSAKSLWLKELDALEEELDKLERKDAEDEGVRKEMRMKTTAGLAPSRPGPKKPRK 1211

Query: 2157 NNAIKGPTVAANDADVGTTSTAMDAGNXXXXXXXXXXXXXXXDAAKKTTVV--XXXXXXX 2330
            N        A N + VG+ +TA DAG                  AK+  VV         
Sbjct: 1212 N-------AANNSSVVGSEATATDAGQKKPRGATKRA------PAKQRVVVESGDEDDDI 1258

Query: 2331 XXXKDRLAAYNLDSSPD-QTFMETES--VAQEVLKMKAPSKRATVRKGKSTMTILXXXXX 2501
               KDRLAAYNLDSSPD    MET    V Q   K +A    A  RK  S + +      
Sbjct: 1259 LALKDRLAAYNLDSSPDHHPAMETTDAVVGQGEDKKQADRNSAATRKATS-IDLSDDEDN 1317

Query: 2502 XXXXXXPAISEDGDDGDFQMVEVXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXQGKSLV 2681
                  PAI ED D+ DF +VE                                    + 
Sbjct: 1318 EAGNHMPAIDEDNDE-DFSVVEAPKGGKGRGKKPAKEKATTTATRKRGL------ALPVS 1370

Query: 2682 SQKLITDVLKPVVNA----SPEKKVRKMRESPFNKKSGSVLGRARGPVVESE---GSIDS 2840
            SQK IT+VLKP  NA    SP+KKVRKMR SPFN KSGSVLGR +G    SE   GS + 
Sbjct: 1371 SQKRITEVLKPAENATTRISPQKKVRKMRASPFNNKSGSVLGRLKGSPSGSEDSGGSSNG 1430

Query: 2841 SPSVNLEVEMNEVPVARNRPKRENRSKVQYV 2933
             PS      +NEV  AR RP+R N ++  YV
Sbjct: 1431 GPS-----PINEVAAARTRPRRANSTRAVYV 1456


>ref|XP_020577441.1| DNA topoisomerase 2 [Phalaenopsis equestris]
          Length = 1468

 Score = 1138 bits (2943), Expect = 0.0
 Identities = 609/983 (61%), Positives = 703/983 (71%), Gaps = 6/983 (0%)
 Frame = +3

Query: 3    KGKLLNVREASLKQIMQNAEIQNIKQILGLQHGKQYDSVKGLRYGSLMIMTDQDHDGSHI 182
            +GKLLNVREAS KQIM+NAEIQNIKQILGLQ GKQYDSVKGLRYG LMIMTDQDHDGSHI
Sbjct: 490  RGKLLNVREASHKQIMENAEIQNIKQILGLQQGKQYDSVKGLRYGHLMIMTDQDHDGSHI 549

Query: 183  KGLLINFIHSFWPSLLKVKGFMVEFITPIVKASHKN-GTVLSFYTMPEYEAWKESLNGNA 359
            KGLLINFIH+FWPSLLK+  F+VEFITPIVKA++K  G V SFYTMPEYEAWKESL GNA
Sbjct: 550  KGLLINFIHTFWPSLLKIPSFLVEFITPIVKATYKKTGKVTSFYTMPEYEAWKESLRGNA 609

Query: 360  TGWTIKYYKGLGTSTAKEGKEYFKQLRKHKKSFVWADEQDGESIELAFSKKKIEARKNWL 539
            + W+IKYYKGLGTST++EGKEYF+ L++HKK FVW+DEQDG++IELAFSKKKIEARKNWL
Sbjct: 610  SSWSIKYYKGLGTSTSQEGKEYFQDLQRHKKDFVWSDEQDGDAIELAFSKKKIEARKNWL 669

Query: 540  RQFEAGTYLDHKEEEIKYSDFVNKELILFSRADLQRSIPSMVDGLKPGQRKILFCAFKRN 719
            RQFE GT+LD  E+ I YSDFVNKELILFS ADLQRSIPSMVDGLKPGQRKILFC+FKRN
Sbjct: 670  RQFEPGTHLDQNEKLISYSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKILFCSFKRN 729

Query: 720  LIKEAKVAQFSGYVSEHSAYHHGEQSLASTIVGMAQDFVGSNNINLFQPKGQFGTRNKGG 899
             +KE K+ QF+GYVSEHSAYHHGEQSLA+TI+GMAQDFVGSNNINL QP GQFGTR++GG
Sbjct: 730  FVKELKIGQFAGYVSEHSAYHHGEQSLATTIIGMAQDFVGSNNINLLQPNGQFGTRHQGG 789

Query: 900  KDAASGRYIYTCLSPITRFLFPKXXXXXXXXXXXXGQSIEPAWYMPIIPMVLVNGSEGIG 1079
            KD AS RYIYT LSPITRFLFPK            GQSIEP WY+PIIPMVLVNGSEGIG
Sbjct: 790  KDHASARYIYTKLSPITRFLFPKEDDLVLDYLTDDGQSIEPTWYVPIIPMVLVNGSEGIG 849

Query: 1080 TGWSSYVPNYNPRDVVANVRRLLNDEPMRPMEPWYRGFKGLIEKSAQKETG-VTYTISGI 1256
            TGWSSY+PNYNPRD+V NVRRLLN+EPM PM PWYRGFKGLIEK+A KETG +TYT++GI
Sbjct: 850  TGWSSYIPNYNPRDIVKNVRRLLNNEPMVPMNPWYRGFKGLIEKTAVKETGAITYTVTGI 909

Query: 1257 IEEVDITTLRITELPIRSWTADYNEFLDAMMKGTDKFKEPFIQDKRAYNDDVIVHFEVIL 1436
            +EE+D TT+ ITELPIR WT DY EFL+++  G DK KEPFI+D R Y+DDV VHFEV L
Sbjct: 910  MEEIDSTTVAITELPIRRWTLDYKEFLESLETGNDKVKEPFIKDFREYSDDVSVHFEVTL 969

Query: 1437 SEENMMAAKQEGXXXXXXXXXXISTSNMHLFDSNGTIKKYDTPEQILEDFFHLRLQFYEK 1616
            SEENM+ AKQEG          ISTSNMHLFD  G IKKYDTPEQILE+FFHLR+ +YEK
Sbjct: 970  SEENMIIAKQEGLDKKFKLATSISTSNMHLFDHKGVIKKYDTPEQILEEFFHLRITYYEK 1029

Query: 1617 RKKVXXXXXXXXXXXXXXXVRFILAVVKGEIIVNNRRRADLFLELHQKGFTPFPKKTKGI 1796
            RKK                VRFIL VV+G IIVN R+ A+LFLEL +KGFTPFPK+TKGI
Sbjct: 1030 RKKALLDTLELELLKLDNKVRFILGVVEGRIIVNKRKGAELFLELKEKGFTPFPKETKGI 1089

Query: 1797 DAAIAGATVDTXXXXXXXXXTVKGVVKASDYEYLLSMSIGSLTLEKVQELCADKQKLDHE 1976
             AA AG T +           + GV KASDY+YL+SMSI SLTLEKVQ+LCA+K+K +  
Sbjct: 1090 GAATAGVTEEAEESEETAEVVIGGV-KASDYDYLISMSIASLTLEKVQKLCAEKEKHEKV 1148

Query: 1977 LEELRSTSSKILWMRDLDALEKQLDELDQKDVEAANMQEKIRRR--NTGAAVPSKAPKKP 2150
            + ELRS S   LW +DLDALEK+LDEL+++D EA   ++K + +  N GAA   KAPKKP
Sbjct: 1149 VVELRSCSPSSLWNKDLDALEKKLDELEKQDAEAEVTRKKNKEKAGNGGAAAAKKAPKKP 1208

Query: 2151 RKNNAIKGPTVAANDADVGTTSTAMDAGNXXXXXXXXXXXXXXXDAAKKTTVVXXXXXXX 2330
            RKNN    P+ A         S  +D+                   AK  +V        
Sbjct: 1209 RKNNT--KPSAAIE-------SMPIDSETVQEVPKPKPKRRQQKSTAKTVSVESDEDEAV 1259

Query: 2331 XXXKDRLAAYNLDSSPDQTFMETESVAQEVLKMKAPSKRATVRKGKSTMTILXXXXXXXX 2510
               KDRLAAYNLDSSP+ + METE+V  E+   K P KRA   K    +           
Sbjct: 1260 IALKDRLAAYNLDSSPETSAMETETVV-EIAAAKGPKKRAGAAKKPLKLD---------- 1308

Query: 2511 XXXPAISEDGDDGDFQMVEVXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXQGKSLVSQK 2690
                +  ED DD +F+  +                                Q KSL+SQK
Sbjct: 1309 ----SDEEDTDDENFENDKAPRGKKGGGGGRKPAANATKTKAITVRKKGDAQNKSLLSQK 1364

Query: 2691 LITDVLKPVVNA--SPEKKVRKMRESPFNKKSGSVLGRARGPVVESEGSIDSSPSVNLEV 2864
            LI+++L P  NA  SPEKKVRK+R SPFNKKSGS+L ++        GS DSS   + E 
Sbjct: 1365 LISELLPPATNAVNSPEKKVRKIRPSPFNKKSGSLLNKSE---TSGSGSQDSSSGASAED 1421

Query: 2865 EMNEVPVARNRPKRENRSKVQYV 2933
                  VAR RPKRENR++V YV
Sbjct: 1422 F-----VARARPKRENRARVVYV 1439


>gb|OVA19386.1| DNA topoisomerase II [Macleaya cordata]
          Length = 1515

 Score = 1134 bits (2934), Expect = 0.0
 Identities = 603/995 (60%), Positives = 698/995 (70%), Gaps = 18/995 (1%)
 Frame = +3

Query: 3    KGKLLNVREASLKQIMQNAEIQNIKQILGLQHGKQYDSVKGLRYGSLMIMTDQDHDGSHI 182
            +GKLLNVREAS KQIM+NAEIQ+IKQILGLQHGK+YDSVK LRYG LMIMTDQDHDGSHI
Sbjct: 513  RGKLLNVREASHKQIMENAEIQSIKQILGLQHGKEYDSVKSLRYGHLMIMTDQDHDGSHI 572

Query: 183  KGLLINFIHSFWPSLLKVKGFMVEFITPIVKASHKNGTVLSFYTMPEYEAWKESLNGNAT 362
            KGLLINFIHSFWPSLLK+  F++EFITPIVKA+HKNG V+SFY+MPEYE WKESL GNA+
Sbjct: 573  KGLLINFIHSFWPSLLKIPSFLIEFITPIVKATHKNGKVMSFYSMPEYEQWKESLGGNAS 632

Query: 363  GWTIKYYKGLGTSTAKEGKEYFKQLRKHKKSFVWADEQDGESIELAFSKKKIEARKNWLR 542
            GW+IKYYKGLGTST+KEGKEYFK L KH+K F+W DEQDG++I+LAFSKKKIEARKNWLR
Sbjct: 633  GWSIKYYKGLGTSTSKEGKEYFKDLEKHRKDFMWVDEQDGDAIDLAFSKKKIEARKNWLR 692

Query: 543  QFEAGTYLDHKEEEIKYSDFVNKELILFSRADLQRSIPSMVDGLKPGQRKILFCAFKRNL 722
            QFE GTYLD KE+ IKYSDFVNKELILFS ADLQRSIPSMVDGLKPGQRKILFC+FKRN 
Sbjct: 693  QFEPGTYLDQKEKLIKYSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKILFCSFKRNF 752

Query: 723  IKEAKVAQFSGYVSEHSAYHHGEQSLASTIVGMAQDFVGSNNINLFQPKGQFGTRNKGGK 902
            +KEAKVAQFSGYVSEHSAYHHGEQSLA TI+GMAQD+VGSNNINL QP GQFGTR++GGK
Sbjct: 753  VKEAKVAQFSGYVSEHSAYHHGEQSLAGTIIGMAQDYVGSNNINLLQPNGQFGTRHQGGK 812

Query: 903  DAASGRYIYTCLSPITRFLFPKXXXXXXXXXXXXGQSIEPAWYMPIIPMVLVNGSEGIGT 1082
            D AS RYIYT LSPITRFLFPK            GQSIEP WY+P+IP VLVNGSEGIGT
Sbjct: 813  DHASARYIYTRLSPITRFLFPKDDDILLDYLNEDGQSIEPTWYVPVIPTVLVNGSEGIGT 872

Query: 1083 GWSSYVPNYNPRDVVANVRRLLNDEPMRPMEPWYRGFKGLIEKSAQKETGVTYTISGIIE 1262
            GWS Y+PNYNPRD+V NV+RLLN EPM PM+PWY+GFKG IEK+A KE GV+YT+SGIIE
Sbjct: 873  GWSCYIPNYNPRDIVENVKRLLNGEPMEPMDPWYKGFKGRIEKTATKEGGVSYTVSGIIE 932

Query: 1263 EVDITTLRITELPIRSWTADYNEFLDAMMKGTDKFKEPFIQDKRAYNDDVIVHFEVILSE 1442
            EV+ TTLRI+ELP+R WT DY EFL+++M G DK KEPFI+D R +NDD  VHFEVILSE
Sbjct: 933  EVNETTLRISELPVRRWTQDYKEFLESIMTGNDKIKEPFIKDYREHNDDTTVHFEVILSE 992

Query: 1443 ENMMAAKQEGXXXXXXXXXXISTSNMHLFDSNGTIKKYDTPEQILEDFFHLRLQFYEKRK 1622
            EN++ AKQEG          +STSNMHLFD  G IKKYD PEQILE+FFHLRL+FYEKRK
Sbjct: 993  ENLVMAKQEGLLKKFKLTTTVSTSNMHLFDPKGVIKKYDNPEQILEEFFHLRLEFYEKRK 1052

Query: 1623 KVXXXXXXXXXXXXXXXVRFILAVVKGEIIVNNRRRADLFLELHQKGFTPFPKKTKGIDA 1802
            +V               VRFIL VVKGEIIV+NR+RADLFLEL QKGFTPFPKKTK ++A
Sbjct: 1053 RVLLENLELELLKLDNKVRFILGVVKGEIIVSNRKRADLFLELQQKGFTPFPKKTKLVEA 1112

Query: 1803 AIAGATVDTXXXXXXXXXTVKGVVKASDYEYLLSMSIGSLTLEKVQELCADKQKLDHELE 1982
             +AGAT DT              V+ASDYEYLLSM+IG+LTLEKVQELC DKQ+LD E++
Sbjct: 1113 VVAGATEDTEENEDNSEALSSRGVRASDYEYLLSMAIGTLTLEKVQELCNDKQRLDGEVD 1172

Query: 1983 ELRSTSSKILWMRDLDALEKQLDELDQKDVEAANMQEKIR---RRNTGAAVPSKAPKKPR 2153
            ELR  +SK LW +DLDALEK+ DE D+ D +A   ++ ++    +  G        K PR
Sbjct: 1173 ELRRATSKSLWKKDLDALEKEFDEQDKNDSKAEEARKVMKSKVMKEAGMKDSKPVAKNPR 1232

Query: 2154 KNNA--IKGPTVAANDADVGTTSTAMDAGNXXXXXXXXXXXXXXXDAAKKTTVV-----X 2312
            KNN   +  P   A  A V +T   M+  N                 AKK          
Sbjct: 1233 KNNTKKVNNPAAVAASAQVSST---MEIENISEAAKPKGRGGPRKAPAKKGKPALVDSDD 1289

Query: 2313 XXXXXXXXXKDRLAAYNLDSSPDQT------FMETESVAQEVLKMKAPSKRATVRKGKST 2474
                     K+RLAAYNLDSSP+Q+       METES      K K  SK  + +K K+T
Sbjct: 1290 EDDDEILELKERLAAYNLDSSPEQSSAGPVAAMETESGIVRA-KNKETSKMVSAQK-KAT 1347

Query: 2475 MTILXXXXXXXXXXXPAISEDGDDGDFQMVEVXXXXXXXXXXXXXXXXXXXXXXXXXXXX 2654
            +T +                + +D + ++V                              
Sbjct: 1348 ITEISDDEDNRNDEQMKTIMENEDFEPEVVVPAGRKGGKRGQTKPAANPKAAKPVTVARK 1407

Query: 2655 XXXQGKSLVSQKLITDVLKPV--VNASPEKKVRKMRESPFNKKSGSVLGRARGPVVESEG 2828
                 K L++Q LITD+LKP   V  SPEKKVRKMR SPFNKKSGS+LGR    V + + 
Sbjct: 1408 RGPTKKQLLNQTLITDILKPAENVGVSPEKKVRKMRASPFNKKSGSLLGR----VAKEDE 1463

Query: 2829 SIDSSPSVNLEVEMNEVPVARNRPKRENRSKVQYV 2933
                  S        EV   R RP+R NR+  +YV
Sbjct: 1464 EESPMGSEQQSGSSGEVVATRARPQRANRTVAKYV 1498


>ref|XP_002274267.1| PREDICTED: DNA topoisomerase 2 [Vitis vinifera]
          Length = 1489

 Score = 1124 bits (2907), Expect = 0.0
 Identities = 600/1002 (59%), Positives = 707/1002 (70%), Gaps = 25/1002 (2%)
 Frame = +3

Query: 3    KGKLLNVREASLKQIMQNAEIQNIKQILGLQHGKQYDSVKGLRYGSLMIMTDQDHDGSHI 182
            +GKLLNVR+A  KQI++NAEIQNIKQILGLQ GK+YDS+K LRYG LMIMTDQDHDGSHI
Sbjct: 482  RGKLLNVRDAQKKQILENAEIQNIKQILGLQQGKEYDSIKSLRYGHLMIMTDQDHDGSHI 541

Query: 183  KGLLINFIHSFWPSLLKVKGFMVEFITPIVKASHKNGTVLSFYTMPEYEAWKESLNGNAT 362
            KGLLINFIHSFWPSLLK+  F+VEFITPIVKA+H+NG VLSFY+MPEYE+WKESL GNA+
Sbjct: 542  KGLLINFIHSFWPSLLKIPSFLVEFITPIVKATHRNGRVLSFYSMPEYESWKESLGGNAS 601

Query: 363  GWTIKYYKGLGTSTAKEGKEYFKQLRKHKKSFVWADEQDGESIELAFSKKKIEARKNWLR 542
            GW+IKYYKGLGTST+KEGKEYFK L KHKK F+W DE+DG++IELAFSKKKIE RKNWLR
Sbjct: 602  GWSIKYYKGLGTSTSKEGKEYFKDLGKHKKDFMWVDEKDGDAIELAFSKKKIEERKNWLR 661

Query: 543  QFEAGTYLDHKEEEIKYSDFVNKELILFSRADLQRSIPSMVDGLKPGQRKILFCAFKRNL 722
            QF+ GTYLD KE+ IKYSDFVNKELILFS ADLQRSIPSMVDGLKPGQRKILFC+FKRN 
Sbjct: 662  QFQPGTYLDQKEKLIKYSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKILFCSFKRNF 721

Query: 723  IKEAKVAQFSGYVSEHSAYHHGEQSLASTIVGMAQDFVGSNNINLFQPKGQFGTRNKGGK 902
            IKEAK+AQFSGYVSEHSAYHHGEQSLASTI+GMAQDFVGSNNINL  P GQFGTR++GGK
Sbjct: 722  IKEAKIAQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRHQGGK 781

Query: 903  DAASGRYIYTCLSPITRFLFPKXXXXXXXXXXXXGQSIEPAWYMPIIPMVLVNGSEGIGT 1082
            D AS RYIYT LSPITRFLFPK            GQSIEP WY+P IPMVLVNGSEGIGT
Sbjct: 782  DHASARYIYTRLSPITRFLFPKDDDILLDYLNEDGQSIEPTWYVPTIPMVLVNGSEGIGT 841

Query: 1083 GWSSYVPNYNPRDVVANVRRLLNDEPMRPMEPWYRGFKGLIEKS-AQKETGVTYTISGII 1259
            GWSS +PNYNPRD++ANVRRLLN E M PM+PWYRGF+G IEK+   K+  V YT+ GII
Sbjct: 842  GWSSSIPNYNPRDIIANVRRLLNGEMMEPMDPWYRGFRGTIEKTDPTKQESVGYTVKGII 901

Query: 1260 EEVDITTLRITELPIRSWTADYNEFLDAMMKGTDKFKEPFIQDKRAYNDDVIVHFEVILS 1439
            EEV+ TTLRI+ELP+R WT DY EFL+++M G DK K+PFI+D + +NDD  VHFEVI+S
Sbjct: 902  EEVNETTLRISELPVRKWTQDYKEFLESIMTGNDKIKDPFIKDYKEHNDDTTVHFEVIMS 961

Query: 1440 EENMMAAKQEGXXXXXXXXXXISTSNMHLFDSNGTIKKYDTPEQILEDFFHLRLQFYEKR 1619
            EEN++ AKQEG          ISTSNMHLFDSNGTIKKY+TPEQILE+FFHLRL+FYEKR
Sbjct: 962  EENLLMAKQEGLLQKFKLTTKISTSNMHLFDSNGTIKKYETPEQILEEFFHLRLEFYEKR 1021

Query: 1620 KKVXXXXXXXXXXXXXXXVRFILAVVKGEIIVNNRRRADLFLELHQKGFTPFPKKTKGID 1799
            K+V               VRFIL VV+GEIIV+NR+RADLF ELHQKGFTPFPKK+K ++
Sbjct: 1022 KRVLLDNLELELLKLENKVRFILGVVRGEIIVSNRKRADLFHELHQKGFTPFPKKSKSVE 1081

Query: 1800 AAIAGATVDTXXXXXXXXXTVKGVVKASDYEYLLSMSIGSLTLEKVQELCADKQKLDHEL 1979
             A+AGAT DT           KG V+A+DYEYLLSM+IG+LTLEKVQELCAD+ KL+  +
Sbjct: 1082 IAVAGATDDTEEAEENTDAVSKGGVRATDYEYLLSMAIGTLTLEKVQELCADRDKLNKGV 1141

Query: 1980 EELRSTSSKILWMRDLDALEKQLDELDQKDVEAANMQEKIRRR---NTGAAVPSKAPKKP 2150
            ++L+  + K LW+ DLDALE++LDE D+ D  A   +++++ R     G  V  +APK P
Sbjct: 1142 DDLKKATPKALWITDLDALERELDEQDKNDARAEETRKQLKSRVMSEAGMKVSRQAPKNP 1201

Query: 2151 RKNN-AIKGPTVAANDADVGTTSTAMDAGNXXXXXXXXXXXXXXXDAAKK-----TTVVX 2312
            RKNN        AA   DV + S+AM+  +                 AKK     + +  
Sbjct: 1202 RKNNKKANNAEPAAETMDV-SASSAMEMESVPEVVKPKGRAAPRKAPAKKKEMPTSVLKD 1260

Query: 2313 XXXXXXXXXKDRLAAYNLDSSPD-QTFMETESVAQEVLKMKAPSKRATVRKGKSTMTILX 2489
                     K+RLAAYNL+SSPD    ME E       + K PS+RA  +K         
Sbjct: 1261 EDDDEVHELKERLAAYNLESSPDGSAAMEAEVPQVPAARKKEPSRRAAAQK--------- 1311

Query: 2490 XXXXXXXXXXPAISEDGDDGDFQMVEV-------XXXXXXXXXXXXXXXXXXXXXXXXXX 2648
                          +D DD DF++ EV                                 
Sbjct: 1312 ---KPLASFTEISDDDEDDEDFEVEEVSASDVKKKGGRKPAANAKAAAAKPAAAAAKNKR 1368

Query: 2649 XXXXXQGKSLVSQKLITDVLKP--VVNASPEKKVRKMRESPFNKKSGSVLGRARGPVVES 2822
                 Q   L+ Q L+T++ KP   +  SPEKKVRKMR SPFNKKSGSVLG + G   E+
Sbjct: 1369 GAANKQQPQLLGQTLLTEIFKPAETLGISPEKKVRKMRASPFNKKSGSVLG-STGEEDET 1427

Query: 2823 ----EGSIDSSPSVNLEVEMNEVPV-ARNRPKRENRSKVQYV 2933
                E S  +S S +   E NEV + AR RP+RENR + +YV
Sbjct: 1428 AETEENSGSASTSNSSGGESNEVVMPARTRPQRENRVQTRYV 1469


>emb|CDP07797.1| unnamed protein product [Coffea canephora]
          Length = 1486

 Score = 1117 bits (2890), Expect = 0.0
 Identities = 599/999 (59%), Positives = 698/999 (69%), Gaps = 22/999 (2%)
 Frame = +3

Query: 3    KGKLLNVREASLKQIMQNAEIQNIKQILGLQHGKQYDSVKGLRYGSLMIMTDQDHDGSHI 182
            +GKLLNVREAS KQIM NAEIQ IKQILGLQHGK YDSVK LRYG LMIMTDQDHDGSHI
Sbjct: 483  RGKLLNVREASHKQIMDNAEIQYIKQILGLQHGKVYDSVKSLRYGHLMIMTDQDHDGSHI 542

Query: 183  KGLLINFIHSFWPSLLKVKGFMVEFITPIVKASHKNGTVLSFYTMPEYEAWKESLNGNAT 362
            KGLLINFIHSFWPSLLK+  F+VEFITPIVKA+HKNG VLSFYTMPEYE+WKESL+GNAT
Sbjct: 543  KGLLINFIHSFWPSLLKIPSFLVEFITPIVKATHKNGRVLSFYTMPEYESWKESLSGNAT 602

Query: 363  GWTIKYYKGLGTSTAKEGKEYFKQLRKHKKSFVWADEQDGESIELAFSKKKIEARKNWLR 542
            GW+IKYYKGLGTST+KEGKEYFK L KHKK F+W D+ DGE+IELAFSKKKIEARKNWLR
Sbjct: 603  GWSIKYYKGLGTSTSKEGKEYFKDLGKHKKDFIWVDDNDGEAIELAFSKKKIEARKNWLR 662

Query: 543  QFEAGTYLDHKEEEIKYSDFVNKELILFSRADLQRSIPSMVDGLKPGQRKILFCAFKRNL 722
            QFE GTYLD KE+ IKYSDF+NKELILFS ADLQRSIPSMVDGLKPGQRKILFC+FKRN 
Sbjct: 663  QFEPGTYLDQKEKLIKYSDFINKELILFSLADLQRSIPSMVDGLKPGQRKILFCSFKRNF 722

Query: 723  IKEAKVAQFSGYVSEHSAYHHGEQSLASTIVGMAQDFVGSNNINLFQPKGQFGTRNKGGK 902
            +KEAKVAQFSGYVSEHSAYHHGEQSLAS I+GMAQDFVGSNNINL QP GQFGTRN+GGK
Sbjct: 723  VKEAKVAQFSGYVSEHSAYHHGEQSLASAIIGMAQDFVGSNNINLLQPNGQFGTRNQGGK 782

Query: 903  DAASGRYIYTCLSPITRFLFPKXXXXXXXXXXXXGQSIEPAWYMPIIPMVLVNGSEGIGT 1082
            D AS RY+YT LSPITR LFPK            GQSIEP WYMPIIPMVLVNGSEGIGT
Sbjct: 783  DHASARYVYTRLSPITRSLFPKDDDILLDYLNEDGQSIEPTWYMPIIPMVLVNGSEGIGT 842

Query: 1083 GWSSYVPNYNPRDVVANVRRLLNDEPMRPMEPWYRGFKGLIEKSAQKETGVTYTISGIIE 1262
            GWSSY+PNYNPRD++ N+RRLLN+EPM PMEPWY+GF+G IEK+A KE G +YT+SGI+E
Sbjct: 843  GWSSYIPNYNPRDIIGNIRRLLNNEPMEPMEPWYKGFRGTIEKTATKEAGASYTVSGIVE 902

Query: 1263 EVDITTLRITELPIRSWTADYNEFLDAMMKGTDKFKEPFIQDKRAYNDDVIVHFEVILSE 1442
            EVD TT+R+TELP+R WT DY EFL+++M G +K K+PFI++ R + DD  V+ ++I+SE
Sbjct: 903  EVDETTIRVTELPVRKWTQDYKEFLESIMMGNEKVKDPFIKEFRDHTDDTTVYLDIIMSE 962

Query: 1443 ENMMAAKQEGXXXXXXXXXXISTSNMHLFDSNGTIKKYDTPEQILEDFFHLRLQFYEKRK 1622
            EN++ AKQEG          ISTSNMHLFDS G IKK+D PEQILE+FFHLRL+FYEKRK
Sbjct: 963  ENLLMAKQEGLLKKFKLTTTISTSNMHLFDSQGIIKKFDNPEQILEEFFHLRLEFYEKRK 1022

Query: 1623 KVXXXXXXXXXXXXXXXVRFILAVVKGEIIVNNRRRADLFLELHQKGFTPFPKKTKGIDA 1802
            KV               VRFILAVV+G IIV+NR+RADLFLEL +KGFTPFPKK K ++A
Sbjct: 1023 KVLLDNLQLELLKLDNKVRFILAVVEGSIIVSNRKRADLFLELKEKGFTPFPKK-KSVEA 1081

Query: 1803 AIAGATVDTXXXXXXXXXTVKGVVKASDYEYLLSMSIGSLTLEKVQELCADKQKLDHELE 1982
            A+AG+  D               V+ASDYEYL+SM+IGSLTLEKVQELCAD+ KL  E++
Sbjct: 1082 AVAGSIEDAEETEESSEVATSKGVRASDYEYLISMAIGSLTLEKVQELCADRDKLKGEVD 1141

Query: 1983 ELRSTSSKILWMRDLDALEKQLDELDQKDVEAANMQEKIR---RRNTGAAVPSKAPKKPR 2153
            +L   + K LW +DLDALE QLDE D  D +A   ++++R    ++ G     +APK PR
Sbjct: 1142 DLIKATPKSLWTKDLDALESQLDEQDISDAQAEAARKEMRSKAMKDDGPKPTRQAPKNPR 1201

Query: 2154 KNNAIKGPTVAANDADVGTTSTAMDAGNXXXXXXXXXXXXXXXDAAKKTTVV-------X 2312
            K N     T    +    ++S+A++  N                 A+K            
Sbjct: 1202 KYNKKASNTEPTTEPMEISSSSALETNNVVEVAKPKGKAGPKKAPARKGKTFSVLRDEDD 1261

Query: 2313 XXXXXXXXXKDRLAAYNL-DSSPDQT-FMETESVAQEVLKMKAPSKRATVRKGKSTMTIL 2486
                     KDRLAAYNL  SSPDQ+  METE      +  + PSKRAT +K   ++T +
Sbjct: 1262 EDDDEVLALKDRLAAYNLGSSSPDQSETMETE------IPKREPSKRATTKKPLVSVTEI 1315

Query: 2487 XXXXXXXXXXXPAISEDGDDGDFQMVEVXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXQ 2666
                           E  DD DF++ EV                               +
Sbjct: 1316 SDDDDDQI-------EISDDEDFEL-EVEAAPKEKGRKKTANSKAAKPTAAPKKRGQANK 1367

Query: 2667 GKSLVSQKLITDVLKP--VVNASPEKKVRKMRESPFNKKSGSVLGRAR-------GPVVE 2819
               LV QKLIT+VLKP  V   SPEKKVR+MR SPFNKKSGSVL R          P  E
Sbjct: 1368 TSQLVGQKLITEVLKPADVSKISPEKKVRRMRPSPFNKKSGSVLERLSQQETDKISPESE 1427

Query: 2820 SEGSIDSSPSVNLEVEMNEVPVARNRPKR-ENRSKVQYV 2933
             +    +S +     E  +V V R RP+R  NR K +YV
Sbjct: 1428 EQEESPASNASGSTEESAQVVVPRARPRRGGNRGKAKYV 1466


>gb|EOY18138.1| DNA topoisomerase 2 isoform 2 [Theobroma cacao]
          Length = 1285

 Score = 1110 bits (2871), Expect = 0.0
 Identities = 606/992 (61%), Positives = 696/992 (70%), Gaps = 15/992 (1%)
 Frame = +3

Query: 3    KGKLLNVREASLKQIMQNAEIQNIKQILGLQHGKQYDSVKGLRYGSLMIMTDQDHDGSHI 182
            +GKLLNVREAS KQ+M NAEIQN+K+ILGLQ GK+Y +VK LRYG LMIMTDQDHDGSHI
Sbjct: 290  RGKLLNVREASHKQLMDNAEIQNLKRILGLQQGKEYSNVKSLRYGHLMIMTDQDHDGSHI 349

Query: 183  KGLLINFIHSFWPSLLKVKGFMVEFITPIVKASHKNGTVLSFYTMPEYEAWKESLNGNAT 362
            KGLLINFIHSFWPSLLKV  FMVEFITPIVKA+HK   VLSFY+MPEYE WKESL GNA 
Sbjct: 350  KGLLINFIHSFWPSLLKVPSFMVEFITPIVKATHKTKGVLSFYSMPEYEFWKESLGGNAK 409

Query: 363  GWTIKYYKGLGTSTAKEGKEYFKQLRKHKKSFVWADEQDGESIELAFSKKKIEARKNWLR 542
            GW+IKYYKGLGTST+KEGK+YFK L KH+K FVW DEQDGE+IELAFSKKKIEARKNWLR
Sbjct: 410  GWSIKYYKGLGTSTSKEGKDYFKNLDKHRKEFVWQDEQDGEAIELAFSKKKIEARKNWLR 469

Query: 543  QFEAGTYLDHKEEEIKYSDFVNKELILFSRADLQRSIPSMVDGLKPGQRKILFCAFKRNL 722
            QFE GT+LD  ++ IKYS+F+NKELILFS ADLQRSIPSM+DGLKPGQRKILFC+FKRN 
Sbjct: 470  QFEPGTHLDQSQKLIKYSEFINKELILFSMADLQRSIPSMIDGLKPGQRKILFCSFKRNF 529

Query: 723  IKEAKVAQFSGYVSEHSAYHHGEQSLASTIVGMAQDFVGSNNINLFQPKGQFGTRNKGGK 902
            +KEAKVAQFSGYVSEHSAYHHGEQSLASTIVGMAQDFVGSNNINL  P GQFGTRN+GGK
Sbjct: 530  VKEAKVAQFSGYVSEHSAYHHGEQSLASTIVGMAQDFVGSNNINLLNPGGQFGTRNQGGK 589

Query: 903  DAASGRYIYTCLSPITRFLFPKXXXXXXXXXXXXGQSIEPAWYMPIIPMVLVNGSEGIGT 1082
            DAAS RYI+T LSPITR+LFPK            GQSIEP WY+PIIPMVLVNGSEGIGT
Sbjct: 590  DAASARYIFTNLSPITRYLFPKDDDGLLDYLNEDGQSIEPIWYVPIIPMVLVNGSEGIGT 649

Query: 1083 GWSSYVPNYNPRDVVANVRRLLNDEPMRPMEPWYRGFKGLIEKSAQKETGVTYTISGIIE 1262
            GWSSY+PNYNPRD+VANVRRLLN E M PM PWYRGFKG IEK+A KE GVTYTI+GIIE
Sbjct: 650  GWSSYIPNYNPRDIVANVRRLLNGEQMEPMHPWYRGFKGNIEKTASKEAGVTYTITGIIE 709

Query: 1263 EVDITTLRITELPIRSWTADYNEFLDAMMKGTDKFKEPFIQDKRAYNDDVIVHFEVILSE 1442
            EVD TTLRITELP+R WT DY EFL++++ G D    PFI++ R Y+DD  V FEVIL+E
Sbjct: 710  EVDETTLRITELPVRRWTQDYREFLESIITGND----PFIKEFRQYSDDTTVEFEVILTE 765

Query: 1443 ENMMAAKQEGXXXXXXXXXXISTSNMHLFDSNGTIKKYDTPEQILEDFFHLRLQFYEKRK 1622
            ENMM AKQEG          ISTSNMHLFDS G IKKYDTPEQILE+FFHLR +FYEKRK
Sbjct: 766  ENMMVAKQEGLLKKFKLTTTISTSNMHLFDSKGMIKKYDTPEQILEEFFHLRFEFYEKRK 825

Query: 1623 KVXXXXXXXXXXXXXXXVRFILAVVKGEIIVNNRRRADLFLELHQKGFTPFPKKTKGIDA 1802
            K+               VRFIL VVKGEIIVNNR+RADLFLEL  KGFTPFPKK K ++ 
Sbjct: 826  KLLLDNLEMELLKMENKVRFILGVVKGEIIVNNRKRADLFLELQTKGFTPFPKKAKTVEV 885

Query: 1803 AIAGATVDTXXXXXXXXXTVKGVVKASDYEYLLSMSIGSLTLEKVQELCADKQKLDHELE 1982
            A+AGAT DT         + KG ++ASDY+YLLSM+IGSLTLEKVQELCAD+ KL  E+E
Sbjct: 886  AVAGATDDTEETEENSEVSAKG-LQASDYDYLLSMAIGSLTLEKVQELCADRDKLQQEVE 944

Query: 1983 ELRSTSSKILWMRDLDALEKQLDELDQKDVEAANMQEKIR-RRNTGAAVPSKAPKKPRK- 2156
            +LR  + K LW++DLD LE QLDE D K  +A    + ++ R   G     +APK PRK 
Sbjct: 945  DLRKATPKSLWLKDLDNLEIQLDEQD-KAAQAEEAAKLVKGRGEAGKRAQRQAPKIPRKI 1003

Query: 2157 NNAIKGPTVAANDADVGTTSTAMDAGNXXXXXXXXXXXXXXXDAAK-KTTVVXXXXXXXX 2333
            N   K         D+ ++S+AM+                   A K  +           
Sbjct: 1004 NKKEKNAETVTETTDI-SSSSAMETAETAPAAVKPKGRGGSRKAKKDDSDDDDDEDFGIP 1062

Query: 2334 XXKDRLAAYNLDSSPDQT-FMETESVAQEVLKMKAPSKRATVRKGKSTMTILXXXXXXXX 2510
              ++RLA YNLDSSPD +  METE V Q     K PSKRA   + K   ++         
Sbjct: 1063 DLRERLAKYNLDSSPDHSAAMETE-VPQVPAGKKEPSKRAAAARKKPATSL--------S 1113

Query: 2511 XXXPAISE-DGDDGDFQMVEVXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXQ-----GK 2672
                +I E D +D D ++VEV                               +     GK
Sbjct: 1114 EISESIGEIDINDEDLEVVEVAAAAAPAGKKGGRKPAANSKAAAKPPAAAKKRGPAAAGK 1173

Query: 2673 SLVSQKLITDVLKPVVNA--SPEKKVRKMRESPFNKKSGSVLGRARGPV---VESEGSID 2837
                QKL+T++LKP  ++  SPEKKVRKMR SPFNKKSGSVLGR    +    +SE +  
Sbjct: 1174 KSQQQKLLTEMLKPAEDSGISPEKKVRKMRASPFNKKSGSVLGRVGKELESTTDSEETFG 1233

Query: 2838 SSPSVNLEVEMNEVPVARNRPKRENRSKVQYV 2933
            SS       E+ E+  AR RP+R NR +  YV
Sbjct: 1234 SSSMSADTEEVTEIVPARPRPQRTNRKQTTYV 1265


>ref|XP_010023678.1| PREDICTED: DNA topoisomerase 2 [Eucalyptus grandis]
 gb|KCW60013.1| hypothetical protein EUGRSUZ_H02748 [Eucalyptus grandis]
          Length = 1496

 Score = 1107 bits (2862), Expect = 0.0
 Identities = 592/988 (59%), Positives = 686/988 (69%), Gaps = 11/988 (1%)
 Frame = +3

Query: 3    KGKLLNVREASLKQIMQNAEIQNIKQILGLQHGKQYDSVKGLRYGSLMIMTDQDHDGSHI 182
            +GKLLNVREAS  QIM+N EIQ IKQILGLQ  K YDSVK LRYG LMIMTDQDHDGSHI
Sbjct: 499  RGKLLNVREASHSQIMENKEIQYIKQILGLQQNKDYDSVKSLRYGHLMIMTDQDHDGSHI 558

Query: 183  KGLLINFIHSFWPSLLKVKGFMVEFITPIVKASHKNGTVLSFYTMPEYEAWKESLNGNAT 362
            KGLLINF+HSFWPSLLKV  F+VEFITPIVKA+HKNG  LSFYTMPEYE+WKESL G+ +
Sbjct: 559  KGLLINFVHSFWPSLLKVPSFLVEFITPIVKATHKNGRELSFYTMPEYESWKESLGGSGS 618

Query: 363  GWTIKYYKGLGTSTAKEGKEYFKQLRKHKKSFVWADEQDGESIELAFSKKKIEARKNWLR 542
            GW+IKYYKGLGTST+KEGK+YF+ L  HKK FVW D+QDG++IELAFSKKKIEARK WLR
Sbjct: 619  GWSIKYYKGLGTSTSKEGKQYFQNLDMHKKDFVWVDDQDGDAIELAFSKKKIEARKTWLR 678

Query: 543  QFEAGTYLDHKEEEIKYSDFVNKELILFSRADLQRSIPSMVDGLKPGQRKILFCAFKRNL 722
            QFE GTYLD KE+ IKYSDFVNKELILFS ADLQRSIPSMVDGLKPGQRKILFC+FKRN 
Sbjct: 679  QFEPGTYLDQKEKLIKYSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKILFCSFKRNF 738

Query: 723  IKEAKVAQFSGYVSEHSAYHHGEQSLASTIVGMAQDFVGSNNINLFQPKGQFGTRNKGGK 902
            IKEAKVAQFSGYVSEHSAYHHGEQSLASTI+GMAQD+VGSNNINL  P GQFGTRN GGK
Sbjct: 739  IKEAKVAQFSGYVSEHSAYHHGEQSLASTIIGMAQDYVGSNNINLLMPNGQFGTRNMGGK 798

Query: 903  DAASGRYIYTCLSPITRFLFPKXXXXXXXXXXXXGQSIEPAWYMPIIPMVLVNGSEGIGT 1082
            D AS RY+YT LSP TRFLFPK            GQSIEP WYMPI+PMVLVNGSEGIGT
Sbjct: 799  DHASPRYVYTKLSPTTRFLFPKDDDNLLSYLNEDGQSIEPTWYMPILPMVLVNGSEGIGT 858

Query: 1083 GWSSYVPNYNPRDVVANVRRLLNDEPMRPMEPWYRGFKGLIEKSAQKETGVTYTISGIIE 1262
            GWSSY+PNYNPRD++AN+RRLLN E M PM+PWYRGF+G IEK+A KE GVTYT+ GIIE
Sbjct: 859  GWSSYIPNYNPRDIIANLRRLLNGEMMEPMDPWYRGFRGTIEKTATKEAGVTYTVCGIIE 918

Query: 1263 EVDITTLRITELPIRSWTADYNEFLDAMMKGT-DKFKEPFIQDKRAYNDDVIVHFEVILS 1439
            EVD TTLRITELPIR WT DY EFL+++  G  DK K+PF+++ R Y+DDV VHFEV+L+
Sbjct: 919  EVDDTTLRITELPIRRWTQDYREFLESLSTGEKDKAKDPFVKEFRQYSDDVTVHFEVMLT 978

Query: 1440 EENMMAAKQEGXXXXXXXXXXISTSNMHLFDSNGTIKKYDTPEQILEDFFHLRLQFYEKR 1619
            EENMM AKQEG          ISTSNMHLFD NG IKKYD+PEQILE+FFHLRL+ YEKR
Sbjct: 979  EENMMIAKQEGLLKKFKLTSSISTSNMHLFDPNGVIKKYDSPEQILEEFFHLRLECYEKR 1038

Query: 1620 KKVXXXXXXXXXXXXXXXVRFILAVVKGEIIVNNRRRADLFLELHQKGFTPFPKKTKGID 1799
            KK+               VRFIL VV GEIIV+NR+RADLF EL  KGFTPF K+TK I+
Sbjct: 1039 KKILLENLELKLVMLDNKVRFILGVVHGEIIVSNRKRADLFQELQAKGFTPFRKETKTIE 1098

Query: 1800 AAIAGATVDTXXXXXXXXXTVKGVVKASDYEYLLSMSIGSLTLEKVQELCADKQKLDHEL 1979
             A+AG+T D          T KGV KASDYEYLLSM+IG+LTLEKVQELCADK KL  E+
Sbjct: 1099 TAVAGSTDDAEETEENSEPTTKGV-KASDYEYLLSMAIGALTLEKVQELCADKDKLVDEV 1157

Query: 1980 EELRSTSSKILWMRDLDALEKQLDELDQKDVEAANMQEKIRRRN-TGAAVPSKAPKKPRK 2156
            + LR  + + LW+ DL ALE++LDE ++ D +A   ++   + N  G  V  +APKKPRK
Sbjct: 1158 DALRKATPENLWLEDLAALEEKLDEQEKMDAQAEETRKARSKANGVGTKVSRQAPKKPRK 1217

Query: 2157 NNAIKGPTVAANDADVGTTSTAMDAGNXXXXXXXXXXXXXXXDAAKKTTVVXXXXXXXXX 2336
            N+       A  +   G+T T ++AGN                 A K +           
Sbjct: 1218 NDTKANNPEAQAEVTQGSTVT-LEAGNAADVAKPKRGAGARKAPAPKPSKSASVSDDDED 1276

Query: 2337 X-----KDRLAAYNLDSSPDQTFMETESVAQEVLKMKAPSKRATVRKGKSTMTILXXXXX 2501
                  K+RLAAYNL+SSPD +    + V +  +K K PSKRA  RK  S +        
Sbjct: 1277 FEMLDLKERLAAYNLESSPDNSSALEDKVPEIPVKEKEPSKRAATRKKPSVI-------- 1328

Query: 2502 XXXXXXPAISEDGDDGDFQMV--EVXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXQGKS 2675
                     S D  D D++ V  E                                Q   
Sbjct: 1329 LSEISEEENSNDSGDDDYETVDSEAEVAKKKGGRKPSAAAKKSKPPAATKKGQANRQQAR 1388

Query: 2676 LVSQKLITDVLKPV--VNASPEKKVRKMRESPFNKKSGSVLGRARGPVVESEGSIDSSPS 2849
              SQ+L+T++LKP      SPEKKVRKMR SPFNKKS S+LG+       +   + S+P 
Sbjct: 1389 GTSQRLLTEMLKPAESTGVSPEKKVRKMRASPFNKKSSSLLGKEGKADSSTSEEMSSNPM 1448

Query: 2850 VNLEVEMNEVPVARNRPKRENRSKVQYV 2933
             N   ++ EV   + RP+R NR +  YV
Sbjct: 1449 SNDGEDVVEVAPPKRRPQRVNRKQTTYV 1476


>ref|XP_021295966.1| DNA topoisomerase 2 [Herrania umbratica]
          Length = 1475

 Score = 1106 bits (2861), Expect = 0.0
 Identities = 602/993 (60%), Positives = 693/993 (69%), Gaps = 16/993 (1%)
 Frame = +3

Query: 3    KGKLLNVREASLKQIMQNAEIQNIKQILGLQHGKQYDSVKGLRYGSLMIMTDQDHDGSHI 182
            +GKLLNVREAS KQ+M NAEIQN+K+ILGLQ GK+Y +VK LRYG LMIMTDQDHDGSHI
Sbjct: 479  RGKLLNVREASHKQLMDNAEIQNLKRILGLQQGKEYTNVKSLRYGHLMIMTDQDHDGSHI 538

Query: 183  KGLLINFIHSFWPSLLKVKGFMVEFITPIVKASHKNGTVLSFYTMPEYEAWKESLNGNAT 362
            KGLLINFIHSFWPSLLKV  FMVEFITPIVKA+HK   VLSFY+MPEYE+WKE L GNA 
Sbjct: 539  KGLLINFIHSFWPSLLKVPSFMVEFITPIVKATHKTKGVLSFYSMPEYESWKERLGGNAK 598

Query: 363  GWTIKYYKGLGTSTAKEGKEYFKQLRKHKKSFVWADEQDGESIELAFSKKKIEARKNWLR 542
            GW+IKYYKGLGTST+KEGK+YFK L KHKK FVW  +QDGE+IELAFSKKKIEARKNWLR
Sbjct: 599  GWSIKYYKGLGTSTSKEGKDYFKNLDKHKKEFVWQGDQDGEAIELAFSKKKIEARKNWLR 658

Query: 543  QFEAGTYLDHKEEEIKYSDFVNKELILFSRADLQRSIPSMVDGLKPGQRKILFCAFKRNL 722
            QFE GT+LD  ++ IKYS+F+NKELILFS ADLQRSIPSM+DGLKPGQRKILFC+FKRN 
Sbjct: 659  QFEPGTHLDQSQKLIKYSEFINKELILFSMADLQRSIPSMIDGLKPGQRKILFCSFKRNF 718

Query: 723  IKEAKVAQFSGYVSEHSAYHHGEQSLASTIVGMAQDFVGSNNINLFQPKGQFGTRNKGGK 902
            +KEAKVAQFSGYVSEHSAYHHGEQSLASTIVGMAQDFVGSNNINL  P GQFGTRN+GGK
Sbjct: 719  VKEAKVAQFSGYVSEHSAYHHGEQSLASTIVGMAQDFVGSNNINLLHPGGQFGTRNQGGK 778

Query: 903  DAASGRYIYTCLSPITRFLFPKXXXXXXXXXXXXGQSIEPAWYMPIIPMVLVNGSEGIGT 1082
            DAAS RYI+T LSPITR+LFPK            GQSIEP WY+PIIPMVLVNGSEGIGT
Sbjct: 779  DAASARYIFTNLSPITRYLFPKDDDGVLDYLNEDGQSIEPIWYVPIIPMVLVNGSEGIGT 838

Query: 1083 GWSSYVPNYNPRDVVANVRRLLNDEPMRPMEPWYRGFKGLIEKSAQKETGVTYTISGIIE 1262
            GWSSY+PNYNPRD+VANVRRLLNDE M PM PWYRGFKG IEK+A KE GVTYTI+G+IE
Sbjct: 839  GWSSYIPNYNPRDIVANVRRLLNDEQMEPMHPWYRGFKGNIEKTASKEAGVTYTITGVIE 898

Query: 1263 EVDITTLRITELPIRSWTADYNEFLDAMMKGTDKFKEPFIQDKRAYNDDVIVHFEVILSE 1442
            EVD  TLRITELP+R WT DY EFL++++ G D    PFI++ R Y+DD  V FEVIL+E
Sbjct: 899  EVDEATLRITELPVRRWTQDYREFLESIITGND----PFIKEFRQYSDDTTVEFEVILTE 954

Query: 1443 ENMMAAKQEGXXXXXXXXXXISTSNMHLFDSNGTIKKYDTPEQILEDFFHLRLQFYEKRK 1622
            ENMM AKQEG          ISTSNMHLFDS G IKKYDTPEQILE+FFHLR +FYEKRK
Sbjct: 955  ENMMMAKQEGLLKKFKLTTTISTSNMHLFDSKGMIKKYDTPEQILEEFFHLRFEFYEKRK 1014

Query: 1623 KVXXXXXXXXXXXXXXXVRFILAVVKGEIIVNNRRRADLFLELHQKGFTPFPKKTKGIDA 1802
            K+               VRFIL VVKGEIIVNNR+RADLFLEL  KGFTPFPKK K ++ 
Sbjct: 1015 KLLLDNLEMELLKMENKVRFILGVVKGEIIVNNRKRADLFLELQTKGFTPFPKKAKTVEV 1074

Query: 1803 AIAGATVDTXXXXXXXXXTVKGVVKASDYEYLLSMSIGSLTLEKVQELCADKQKLDHELE 1982
            A+AGAT DT         + KG V+ASDY+YLLSM+IGSLTLEKVQELCAD+ KL  E+E
Sbjct: 1075 AVAGATDDTEETEENSEVSAKG-VQASDYDYLLSMAIGSLTLEKVQELCADRDKLQQEVE 1133

Query: 1983 ELRSTSSKILWMRDLDALEKQLDELDQKDVEAANMQEKIR-RRNTGAAVPSKAPKKPRK- 2156
            +LR  + K LW++DLD LE QLDE D K  +A    + ++ R   G     +APK PRK 
Sbjct: 1134 DLRKATPKSLWLKDLDNLEIQLDEQD-KAAQAEEAAKLVKGRAEAGKRAQRQAPKIPRKI 1192

Query: 2157 NNAIKGPTVAANDADVGTTSTAMDAGNXXXXXXXXXXXXXXXDAAKKTTVVXXXXXXXXX 2336
            N   K        +D+ ++S+AM+  N                    +            
Sbjct: 1193 NKKEKNAETVTETSDI-SSSSAMETENAPAAVKPKGRGGSRKAKKDDSDDDDDEDFGIPD 1251

Query: 2337 XKDRLAAYNLDSSPDQT-FMETESVAQEVLKMKAPSKRATVRKGKSTMTILXXXXXXXXX 2513
             ++RLA YNLDSSPD +  METE V       K PSKRA   + K   ++          
Sbjct: 1252 LRERLAKYNLDSSPDHSAAMETE-VPLVPAGKKEPSKRAAATRKKPASSL--------SE 1302

Query: 2514 XXPAISE-DGDDGDFQMVEVXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXQ-------G 2669
               +I E D +D D  +VEV                               +       G
Sbjct: 1303 ISESIGEIDINDEDLDVVEVEVAAAAAPAGKKGGRKPAANSKAAAKPPAAAKKRGPAASG 1362

Query: 2670 KSLVSQKLITDVLKPVVNA--SPEKKVRKMRESPFNKKSGSVLGRA---RGPVVESEGSI 2834
            K    QKL+T++LKP  ++  SPEKKVRKMR SPFNKKSGSVLGR    +    +SE + 
Sbjct: 1363 KKSQQQKLLTEMLKPAEDSGISPEKKVRKMRASPFNKKSGSVLGRVGKEQESTTDSEETF 1422

Query: 2835 DSSPSVNLEVEMNEVPVARNRPKRENRSKVQYV 2933
             SS       E+ E+  AR RP+R NR +  YV
Sbjct: 1423 GSSSMSADTEEVTEIVPARPRPQRTNRKQTTYV 1455


>ref|XP_006345427.1| PREDICTED: DNA topoisomerase 2 isoform X3 [Solanum tuberosum]
          Length = 1485

 Score = 1093 bits (2828), Expect = 0.0
 Identities = 581/993 (58%), Positives = 700/993 (70%), Gaps = 16/993 (1%)
 Frame = +3

Query: 3    KGKLLNVREASLKQIMQNAEIQNIKQILGLQHGKQYDSVKGLRYGSLMIMTDQDHDGSHI 182
            +GKLLNVREAS KQ+ +N EI++IK+ILGLQ GK+Y+SVK LRYG LMIMTDQDHDGSHI
Sbjct: 479  RGKLLNVREASHKQVSENKEIESIKKILGLQTGKEYESVKSLRYGHLMIMTDQDHDGSHI 538

Query: 183  KGLLINFIHSFWPSLLKVKGFMVEFITPIVKASHKNGTVLSFYTMPEYEAWKESLNGNAT 362
            KGLLINFIH+FWPSLLKV  F+VEFITPIVKA+HK+G +L+FYTMPEYEAW+ SL   ++
Sbjct: 539  KGLLINFIHTFWPSLLKVPSFLVEFITPIVKATHKSGRILAFYTMPEYEAWRRSLGATSS 598

Query: 363  GWTIKYYKGLGTSTAKEGKEYFKQLRKHKKSFVWADEQDGESIELAFSKKKIEARKNWLR 542
            GW+IKYYKGLGTST+KEGKEYF+ L+KH+K F+WAD QDGESIELAFSKKKIEARKNWLR
Sbjct: 599  GWSIKYYKGLGTSTSKEGKEYFQDLQKHRKDFIWADNQDGESIELAFSKKKIEARKNWLR 658

Query: 543  QFEAGTYLDHKEEEIKYSDFVNKELILFSRADLQRSIPSMVDGLKPGQRKILFCAFKRNL 722
            QFE GT+LD KE+ I Y++FVNKELILFS ADLQRSIPSM+DGLKPGQRKILFCAFKRN 
Sbjct: 659  QFEPGTHLDQKEKYISYTEFVNKELILFSMADLQRSIPSMLDGLKPGQRKILFCAFKRNF 718

Query: 723  IKEAKVAQFSGYVSEHSAYHHGEQSLASTIVGMAQDFVGSNNINLFQPKGQFGTRNKGGK 902
            +KEAKV+QFSGYVSEHSAYHHGEQSL+STI+GMAQD+VGSNN+NL QP GQFGTRN GGK
Sbjct: 719  VKEAKVSQFSGYVSEHSAYHHGEQSLSSTIIGMAQDYVGSNNVNLLQPNGQFGTRNMGGK 778

Query: 903  DAASGRYIYTCLSPITRFLFPKXXXXXXXXXXXXGQSIEPAWYMPIIPMVLVNGSEGIGT 1082
            D AS RYIYT LSPI RFLFPK            GQSIEP WY+PIIPMVLVNGSEGIGT
Sbjct: 779  DHASSRYIYTRLSPIARFLFPKDDDTVLDYLNEDGQSIEPTWYIPIIPMVLVNGSEGIGT 838

Query: 1083 GWSSYVPNYNPRDVVANVRRLLNDEPMRPMEPWYRGFKGLIEKSAQKETGVTYTISGIIE 1262
            GWSSYVPNYNPRD+VANVRRLLNDE M PM+PWY+GFKG IEK+A KETG TYT++GIIE
Sbjct: 839  GWSSYVPNYNPRDLVANVRRLLNDELMEPMDPWYKGFKGTIEKTATKETGATYTVTGIIE 898

Query: 1263 EVDITTLRITELPIRSWTADYNEFLDAMMKGTDKFKEPFIQDKRAYNDDVIVHFEVILSE 1442
            E   TTLRI+ELP+R WT DY +FL++M   TDK K+ FI++ RAY D+  V FEVI+SE
Sbjct: 899  EFSETTLRISELPVRRWTEDYKQFLESMTVSTDKSKDAFIKEVRAYGDENSVCFEVIMSE 958

Query: 1443 ENMMAAKQEGXXXXXXXXXXISTSNMHLFDSNGTIKKYDTPEQILEDFFHLRLQFYEKRK 1622
            EN++ A+QEG          ISTSNMHLFDS G IKKYD PE+ILE+F+H+RL++YEKRK
Sbjct: 959  ENLLLAQQEGLLKKFKLTTTISTSNMHLFDSKGKIKKYDAPEEILEEFYHVRLEYYEKRK 1018

Query: 1623 KVXXXXXXXXXXXXXXXVRFILAVVKGEIIVNNRRRADLFLELHQKGFTPFPKKTKGIDA 1802
            K                VRFIL VVKGEIIVNNR+RADL LEL  KGFTPFPKK K ++A
Sbjct: 1019 KTLLEILELELLRIENKVRFILGVVKGEIIVNNRKRADLLLELKNKGFTPFPKK-KPVEA 1077

Query: 1803 AIAGATVDTXXXXXXXXXTVKGVVKASDYEYLLSMSIGSLTLEKVQELCADKQKLDHELE 1982
             +A +T D          + KG V+ASDY+YLLSM+IG+LTLEKVQELCAD+ KL+ E+E
Sbjct: 1078 VVADSTDDAEDSEESPEESNKG-VRASDYDYLLSMAIGTLTLEKVQELCADRDKLNAEVE 1136

Query: 1983 ELRSTSSKILWMRDLDALEKQLDELDQKDVEAANMQEKIRRR--NTGAAVPSKAPKKPRK 2156
            ++R+ + K LWM+DLD L+KQLDE D+ D++    +EK++++  N     P   P+K  K
Sbjct: 1137 DMRNATPKDLWMKDLDVLDKQLDEQDKLDIQTEEAREKLKKKVMNAAGKAPKPKPRKTTK 1196

Query: 2157 NNAIKGPTVAANDADVGTTSTAMDAGNXXXXXXXXXXXXXXXDAAKKTTVV-XXXXXXXX 2333
              A+   T    D  VG+ +   +                    AK   V          
Sbjct: 1197 KAAVVESTAEPMDVSVGSMAETANVTEVAKPKGRGGGSKKAPAKAKPVVVEDEEEEDEVL 1256

Query: 2334 XXKDRLAAYNLDSSPDQTFMETESVAQEVLKMKAPSKRATVRKGKSTMTILXXXXXXXXX 2513
              KDRLAAYNL+SSPD++ + TE+ A +  + KAP+KRA  +K     T           
Sbjct: 1257 ALKDRLAAYNLNSSPDRSEV-TETEAPKA-QTKAPAKRAAAQKKALPST----------- 1303

Query: 2514 XXPAISED------GDDGDFQMVEVXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXQGKS 2675
              P +SE        DD +F   EV                               +   
Sbjct: 1304 --PDVSEGEDEIEISDDNEF-APEVAVGGKKKGGRKPAAAKAAAAPKPPKKRAPANKQSQ 1360

Query: 2676 LVSQKLITDVLKPVVNA--SPEKKVRKMRESPFNKKSGSVLGRARGPVVESEGSIDSSPS 2849
             V Q+LIT VLKP  +A  SP++KVRKMRESPFNKKSG+V+GR       +    + SP 
Sbjct: 1361 SVGQRLITQVLKPAEDAGVSPDRKVRKMRESPFNKKSGAVMGRNTSSSSSTSHESEVSPP 1420

Query: 2850 V----NLEVEMNEVPVA-RNRPKRENRSKVQYV 2933
            +    +LE E++EV VA + RP+R NR+K  YV
Sbjct: 1421 IPSLGSLEEEVSEVVVAPKARPQRANRTKTTYV 1453


>ref|XP_015163347.1| PREDICTED: DNA topoisomerase 2 isoform X2 [Solanum tuberosum]
          Length = 1486

 Score = 1093 bits (2827), Expect = 0.0
 Identities = 581/994 (58%), Positives = 700/994 (70%), Gaps = 17/994 (1%)
 Frame = +3

Query: 3    KGKLLNVREASLKQIMQNAEIQNIKQILGLQHGKQYDSVKGLRYGSLMIMTDQDHDGSHI 182
            +GKLLNVREAS KQ+ +N EI++IK+ILGLQ GK+Y+SVK LRYG LMIMTDQDHDGSHI
Sbjct: 479  RGKLLNVREASHKQVSENKEIESIKKILGLQTGKEYESVKSLRYGHLMIMTDQDHDGSHI 538

Query: 183  KGLLINFIHSFWPSLLKVKGFMVEFITPIVKASHKNGTVLSFYTMPEYEAWKESLNGNAT 362
            KGLLINFIH+FWPSLLKV  F+VEFITPIVKA+HK+G +L+FYTMPEYEAW+ SL   ++
Sbjct: 539  KGLLINFIHTFWPSLLKVPSFLVEFITPIVKATHKSGRILAFYTMPEYEAWRRSLGATSS 598

Query: 363  GWTIKYYKGLGTSTAKEGKEYFKQLRKHKKSFVWADEQDGESIELAFSKKKIEARKNWLR 542
            GW+IKYYKGLGTST+KEGKEYF+ L+KH+K F+WAD QDGESIELAFSKKKIEARKNWLR
Sbjct: 599  GWSIKYYKGLGTSTSKEGKEYFQDLQKHRKDFIWADNQDGESIELAFSKKKIEARKNWLR 658

Query: 543  QFEAGTYLDHKEEEIKYSDFVNKELILFSRADLQRSIPSMVDGLKPGQRKILFCAFKRNL 722
            QFE GT+LD KE+ I Y++FVNKELILFS ADLQRSIPSM+DGLKPGQRKILFCAFKRN 
Sbjct: 659  QFEPGTHLDQKEKYISYTEFVNKELILFSMADLQRSIPSMLDGLKPGQRKILFCAFKRNF 718

Query: 723  IKEAKVAQFSGYVSEHSAYHHGEQSLASTIVGMAQDFVGSNNINLFQPKGQFGTRNKGGK 902
            +KEAKV+QFSGYVSEHSAYHHGEQSL+STI+GMAQD+VGSNN+NL QP GQFGTRN GGK
Sbjct: 719  VKEAKVSQFSGYVSEHSAYHHGEQSLSSTIIGMAQDYVGSNNVNLLQPNGQFGTRNMGGK 778

Query: 903  DAASGRYIYTCLSPITRFLFPKXXXXXXXXXXXXGQSIEPAWYMPIIPMVLVNGSEGIGT 1082
            D AS RYIYT LSPI RFLFPK            GQSIEP WY+PIIPMVLVNGSEGIGT
Sbjct: 779  DHASSRYIYTRLSPIARFLFPKDDDTVLDYLNEDGQSIEPTWYIPIIPMVLVNGSEGIGT 838

Query: 1083 GWSSYVPNYNPRDVVANVRRLLNDEPMRPMEPWYRGFKGLIEKSAQKETGVTYTISGIIE 1262
            GWSSYVPNYNPRD+VANVRRLLNDE M PM+PWY+GFKG IEK+A KETG TYT++GIIE
Sbjct: 839  GWSSYVPNYNPRDLVANVRRLLNDELMEPMDPWYKGFKGTIEKTATKETGATYTVTGIIE 898

Query: 1263 EVDITTLRITELPIRSWTADYNEFLDAMMKGTDKFKEPFIQDKRAYNDDVIVHFEVILSE 1442
            E   TTLRI+ELP+R WT DY +FL++M   TDK K+ FI++ RAY D+  V FEVI+SE
Sbjct: 899  EFSETTLRISELPVRRWTEDYKQFLESMTVSTDKSKDAFIKEVRAYGDENSVCFEVIMSE 958

Query: 1443 ENMMAAKQEGXXXXXXXXXXISTSNMHLFDSNGTIKKYDTPEQILEDFFHLRLQFYEKRK 1622
            EN++ A+QEG          ISTSNMHLFDS G IKKYD PE+ILE+F+H+RL++YEKRK
Sbjct: 959  ENLLLAQQEGLLKKFKLTTTISTSNMHLFDSKGKIKKYDAPEEILEEFYHVRLEYYEKRK 1018

Query: 1623 KVXXXXXXXXXXXXXXXVRFILAVVKGEIIVNNRRRADLFLELHQKGFTPFPKKTKGIDA 1802
            K                VRFIL VVKGEIIVNNR+RADL LEL  KGFTPFPKK K ++A
Sbjct: 1019 KTLLEILELELLRIENKVRFILGVVKGEIIVNNRKRADLLLELKNKGFTPFPKK-KPVEA 1077

Query: 1803 AIAGATVDTXXXXXXXXXTVKGVVKASDYEYLLSMSIGSLTLEKVQELCADKQKLDHELE 1982
             +A +T D          + KG V+ASDY+YLLSM+IG+LTLEKVQELCAD+ KL+ E+E
Sbjct: 1078 VVADSTDDAEDSEESPEESNKG-VRASDYDYLLSMAIGTLTLEKVQELCADRDKLNAEVE 1136

Query: 1983 ELRSTSSKILWMRDLDALEKQLDELDQKDVEAANMQEKIRRR--NTGAAVPSKAPKKPRK 2156
            ++R+ + K LWM+DLD L+KQLDE D+ D++    +EK++++  N     P   P+K  K
Sbjct: 1137 DMRNATPKDLWMKDLDVLDKQLDEQDKLDIQTEEAREKLKKKVMNAAGKAPKPKPRKTTK 1196

Query: 2157 NNAIKGPTVAANDADVGTTSTAMDAGNXXXXXXXXXXXXXXXDAAKKTTVV--XXXXXXX 2330
              A+   T    D  VG+ +   +                      K  VV         
Sbjct: 1197 KAAVVESTAEPMDVSVGSMAETANVTEVAKPKGRGGGSKKAPAKQAKPVVVEDEEEEDEV 1256

Query: 2331 XXXKDRLAAYNLDSSPDQTFMETESVAQEVLKMKAPSKRATVRKGKSTMTILXXXXXXXX 2510
               KDRLAAYNL+SSPD++ + TE+ A +  + KAP+KRA  +K     T          
Sbjct: 1257 LALKDRLAAYNLNSSPDRSEV-TETEAPKA-QTKAPAKRAAAQKKALPST---------- 1304

Query: 2511 XXXPAISED------GDDGDFQMVEVXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXQGK 2672
               P +SE        DD +F   EV                               +  
Sbjct: 1305 ---PDVSEGEDEIEISDDNEF-APEVAVGGKKKGGRKPAAAKAAAAPKPPKKRAPANKQS 1360

Query: 2673 SLVSQKLITDVLKPVVNA--SPEKKVRKMRESPFNKKSGSVLGRARGPVVESEGSIDSSP 2846
              V Q+LIT VLKP  +A  SP++KVRKMRESPFNKKSG+V+GR       +    + SP
Sbjct: 1361 QSVGQRLITQVLKPAEDAGVSPDRKVRKMRESPFNKKSGAVMGRNTSSSSSTSHESEVSP 1420

Query: 2847 SV----NLEVEMNEVPVA-RNRPKRENRSKVQYV 2933
             +    +LE E++EV VA + RP+R NR+K  YV
Sbjct: 1421 PIPSLGSLEEEVSEVVVAPKARPQRANRTKTTYV 1454