BLASTX 2.2.26 [Sep-21-2011]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= Ophiopogon23_contig00015385
         (1721 letters)

Database: All non-redundant GenBank CDS
translations+PDB+SwissProt+PIR+PRF excluding environmental samples
from WGS projects 
           149,584,005 sequences; 54,822,741,787 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

ref|XP_011494888.1| PREDICTED: membrane metallo-endopeptidase-li...   303   7e-91
ref|XP_001600059.2| PREDICTED: neprilysin-11-like isoform X4 [Na...   304   2e-90
ref|XP_008208161.1| PREDICTED: neprilysin-11-like isoform X3 [Na...   304   3e-90
ref|XP_011494889.1| PREDICTED: membrane metallo-endopeptidase-li...   303   3e-90
ref|XP_008208160.1| PREDICTED: membrane metallo-endopeptidase-li...   304   7e-90
ref|XP_008208159.1| PREDICTED: membrane metallo-endopeptidase-li...   304   8e-90
ref|XP_016836925.1| PREDICTED: neprilysin-11-like [Nasonia vitri...   301   3e-89
ref|XP_011312064.1| PREDICTED: membrane metallo-endopeptidase-li...   299   1e-88
ref|XP_011312063.1| PREDICTED: membrane metallo-endopeptidase-li...   299   2e-88
ref|XP_014366580.1| PREDICTED: neprilysin-11 isoform X2 [Papilio...   298   2e-88
ref|XP_015173767.1| PREDICTED: membrane metallo-endopeptidase-li...   299   2e-88
ref|XP_015173766.1| PREDICTED: neprilysin isoform X2 [Polistes d...   299   2e-88
ref|XP_015173765.1| PREDICTED: neprilysin isoform X1 [Polistes d...   299   2e-88
ref|XP_014366579.1| PREDICTED: endothelin-converting enzyme 1 is...   298   6e-88
ref|XP_003701340.1| PREDICTED: membrane metallo-endopeptidase-li...   297   7e-88
ref|XP_017882784.1| PREDICTED: neprilysin isoform X2 [Ceratina c...   297   7e-88
ref|NP_001036959.1| neutral endopeptidase 24.11 [Bombyx mori] >g...   297   8e-88
ref|XP_012548893.1| neutral endopeptidase 24.11 isoform X1 [Bomb...   298   8e-88
ref|XP_012136071.1| PREDICTED: membrane metallo-endopeptidase-li...   297   8e-88
gb|KPJ09289.1| Neprilysin-2 [Papilio machaon]                         298   1e-87

>ref|XP_011494888.1| PREDICTED: membrane metallo-endopeptidase-like 1 isoform X1
            [Ceratosolen solmsi marchali]
          Length = 696

 Score =  303 bits (777), Expect = 7e-91
 Identities = 190/580 (32%), Positives = 313/580 (53%), Gaps = 47/580 (8%)
 Frame = +3

Query: 87   RIEKTLPSSDVACTPCNSKECQDLSNYFDGNMNEEIDPCEDFYEFACGNFSKNAVLDKDT 266
            +I + L + D+  TP     C   ++    NM+  ++PC+DFY FACGNF KN V+  D 
Sbjct: 3    QIVEKLINEDICLTP----GCIHTASLILENMDTSVEPCDDFYRFACGNFLKNTVIPDDK 58

Query: 267  LMESTFTLAGQRIKDKIFNDLEHHKNPYKLKTFDKVKIFYENCKNEKKGNTDGVDYFLEQ 446
               +TF++   +++ ++ + +E   N    + F  VK  Y++C N+ K    G+D   + 
Sbjct: 59   TSVNTFSIISDKLQKQLRSSIEEESNINDPRPFRLVKTLYKSCMNKSKIEEQGLDPLHKI 118

Query: 447  AKEFGGWPLLAGNKWNEDNFEWISLLSKMRSRGFKINYPYTITM------ATLPVISAPS 608
             KE GGWP+L G+ W + NF W   + K R  G+ ++Y    ++      +T  VI    
Sbjct: 119  LKELGGWPVLMGDNWIDSNFNWKESVYKFRRMGYSVDYFLDFSIGIDLKNSTKRVIDLDQ 178

Query: 609  VNKYLELA-AATGKVNKIVRAYYSKMVSLAVMLGADEEVAINEMMEVLAFELKLMKLKVI 785
             +  L     + G  +KIV+AYY  MV +A +LGAD + A+ E+ + L FE+KL  + + 
Sbjct: 179  ASLGLSREYLSKGFNDKIVKAYYIYMVDIAEILGADRQYAMKELKDSLEFEIKLANISLP 238

Query: 786  YE---GTKSLVN-VKVKHLSMIYPTTDWVKLFNTLSNPYDNYFEKDTDIILTNVKLIVSL 953
             E      +L N + V+ L   +PT  W++ FNTL  P  +  E D  +I+     I  L
Sbjct: 239  SEKRRNATALYNLMTVRELDKNFPTIPWLEYFNTLLLPGISITE-DEQVIVNVPSFISDL 297

Query: 954  NQLLKNTPKRVQANYMFWKVFFDSITYMSDD-------YVEVIS-RTDRETL---CKEKV 1100
             +LL+ T KRVQANY+ ++    S++Y++DD       Y  V++ +T+RE     C E V
Sbjct: 298  ERLLQQTSKRVQANYIMFRAAASSVSYLTDDIRKVQLAYSTVVNGKTEREPRWKECVEIV 357

Query: 1101 MNNFQIAVGALYIRKYFNINSREGAIRLLSDIKRQFP---RQISGGPEAMALRTHIKEVF 1271
              +F I++GALY+RKYF  ++++ A+ ++SDI++QF    + +    EA       K V 
Sbjct: 358  SGSFSISIGALYVRKYFKDDAKKNAVEMVSDIRQQFMKILKMVDWMDEATRKSALDKAV- 416

Query: 1272 STMKTIVGYPDDLMNDTVLEEYYNELEISKGSFLSSSLNLTRHG-----EQRKRVYDPED 1436
             +M T + YPD+L++D  LE++Y +LEI+ G++L S LNLT  G     E+ ++  +  D
Sbjct: 417  -SMSTHIAYPDELLDDKKLEKFYKKLEITPGNYLQSILNLTLFGTEYSFEKLRKPVNKSD 475

Query: 1437 W-ANNQEFLLTPNAAYNLVLKSVEISTALLQSPFYGSKNPAYMNYGGMGFVVGHELAHAL 1613
            W A+ +  ++  NA Y+ +  S++    +LQ  F+ +  P YMNYG +GFV+GHE+ H  
Sbjct: 476  WIAHGRPAIV--NAFYSSIENSIQFPAGILQGAFFSNDRPRYMNYGAIGFVMGHEITHG- 532

Query: 1614 YLDEGVMAHEE----------------ERFKCILKQYSKH 1685
            + D+G    +E                +R +CI+ QY  +
Sbjct: 533  FDDQGRQFDKEGNLVEWWAKETKERYLKRAECIIHQYGNY 572


>ref|XP_001600059.2| PREDICTED: neprilysin-11-like isoform X4 [Nasonia vitripennis]
          Length = 764

 Score =  304 bits (778), Expect = 2e-90
 Identities = 186/579 (32%), Positives = 314/579 (54%), Gaps = 47/579 (8%)
 Frame = +3

Query: 90   IEKTLPSSDVACTPCNSKECQDLSNYFDGNMNEEIDPCEDFYEFACGNFSKNAVLDKDTL 269
            +EK+ P  D+    C S  C   ++    NM++ ++PC+DFY FACG+F KN ++  D  
Sbjct: 77   VEKS-PEGDI----CLSPGCIHTASSILENMDQNVEPCDDFYRFACGSFLKNTIIPDDKT 131

Query: 270  MESTFTLAGQRIKDKIFNDLEHHKNPYKLKTFDKVKIFYENCKNEKKGNTDGVDYFLEQA 449
              +TF++   +++ ++ + +E    P   + F  +K  Y+ C N+     +G++   +  
Sbjct: 132  SVNTFSIISDKLQKQLRSSIEEESKPNDPRPFRLLKTLYKTCMNKTLIEEEGLNPLHKIL 191

Query: 450  KEFGGWPLLAGNKWNEDNFEWISLLSKMRSRGFKINYPYTITMATLPVISAPSVNKYLEL 629
            KE GGWP+L G+KW++ +F W   + K   +G+ ++Y    ++    V    S  + ++L
Sbjct: 192  KELGGWPVLVGDKWSDGDFNWKESVYKFGKKGYSVDYFIDFSIG---VDLKNSTKRVIDL 248

Query: 630  AAAT----------GKVNKIVRAYYSKMVSLAVMLGADEEVAINEMMEVLAFELKLMKLK 779
              A+          G  +KIV AYY+ MV +A +LGAD E A  E+ E L FE+KL  + 
Sbjct: 249  DQASLGLSREYLSKGMDDKIVSAYYNYMVDIAEILGADREQAKIELKESLEFEIKLANIS 308

Query: 780  VIYE---GTKSLVN-VKVKHLSMIYPTTDWVKLFNTLSNPYDNYFEKDTDIILTNVKLIV 947
            +  E      +L N + V+ L+  +PT  W++ F+TL  P      +D  +I+     I 
Sbjct: 309  LPSEKRRNATALYNPMTVRQLTQKFPTIPWLEYFSTLL-PSSITVTEDEMVIVNVPSFIT 367

Query: 948  SLNQLLKNTPKRVQANYMFWKVFFDSITYMSDD-------YVEVIS-RTDRETL---CKE 1094
             L +LL+ TPKR+QANY+ W+    S++Y++D+       Y  VIS RT+RE     C +
Sbjct: 368  DLEKLLEQTPKRIQANYVMWRAAATSVSYLNDEIRKRQLAYSTVISGRTEREPRWKECVD 427

Query: 1095 KVMNNFQIAVGALYIRKYFNINSREGAIRLLSDIKRQFPRQISGGPEAM--ALRTHIKEV 1268
             V  +F I+VGALY+RKYFN ++++ A+ ++S+I+ +F ++I    + M    R    + 
Sbjct: 428  IVSGSFSISVGALYVRKYFNEDAKKNAVEMVSNIRGEF-KKILDQVDWMDDETRKAALDK 486

Query: 1269 FSTMKTIVGYPDDLMNDTVLEEYYNELEISKGSFLSSSLNLTRHG-----EQRKRVYDPE 1433
              +M T + YPD+L++DT LE++Y +LEI+ G++L S LNLT  G     E+ ++  +  
Sbjct: 487  ADSMSTHIAYPDELLDDTKLEQFYEKLEITPGNYLESILNLTLFGTQYSFEKLRKPVNKS 546

Query: 1434 DWANNQEFLLTPNAAYNLVLKSVEISTALLQSPFYGSKNPAYMNYGGMGFVVGHELAHAL 1613
            DW  +    +  NA Y+ +  S++    +LQ  F+ +  P YMNYG +GFV+GHE+ H  
Sbjct: 547  DWVTHGRPAIV-NAFYSSIENSIQFPAGILQGAFFSNDRPKYMNYGAIGFVMGHEITHGF 605

Query: 1614 -----------YLDEGVMAHEEERF----KCILKQYSKH 1685
                        L E   A  +E++    +CI+ QY  +
Sbjct: 606  DDQGRQFDKNGNLVEWWAAETKEKYLKRAQCIINQYGNY 644


>ref|XP_008208161.1| PREDICTED: neprilysin-11-like isoform X3 [Nasonia vitripennis]
          Length = 775

 Score =  304 bits (778), Expect = 3e-90
 Identities = 186/579 (32%), Positives = 314/579 (54%), Gaps = 47/579 (8%)
 Frame = +3

Query: 90   IEKTLPSSDVACTPCNSKECQDLSNYFDGNMNEEIDPCEDFYEFACGNFSKNAVLDKDTL 269
            +EK+ P  D+    C S  C   ++    NM++ ++PC+DFY FACG+F KN ++  D  
Sbjct: 88   VEKS-PEGDI----CLSPGCIHTASSILENMDQNVEPCDDFYRFACGSFLKNTIIPDDKT 142

Query: 270  MESTFTLAGQRIKDKIFNDLEHHKNPYKLKTFDKVKIFYENCKNEKKGNTDGVDYFLEQA 449
              +TF++   +++ ++ + +E    P   + F  +K  Y+ C N+     +G++   +  
Sbjct: 143  SVNTFSIISDKLQKQLRSSIEEESKPNDPRPFRLLKTLYKTCMNKTLIEEEGLNPLHKIL 202

Query: 450  KEFGGWPLLAGNKWNEDNFEWISLLSKMRSRGFKINYPYTITMATLPVISAPSVNKYLEL 629
            KE GGWP+L G+KW++ +F W   + K   +G+ ++Y    ++    V    S  + ++L
Sbjct: 203  KELGGWPVLVGDKWSDGDFNWKESVYKFGKKGYSVDYFIDFSIG---VDLKNSTKRVIDL 259

Query: 630  AAAT----------GKVNKIVRAYYSKMVSLAVMLGADEEVAINEMMEVLAFELKLMKLK 779
              A+          G  +KIV AYY+ MV +A +LGAD E A  E+ E L FE+KL  + 
Sbjct: 260  DQASLGLSREYLSKGMDDKIVSAYYNYMVDIAEILGADREQAKIELKESLEFEIKLANIS 319

Query: 780  VIYE---GTKSLVN-VKVKHLSMIYPTTDWVKLFNTLSNPYDNYFEKDTDIILTNVKLIV 947
            +  E      +L N + V+ L+  +PT  W++ F+TL  P      +D  +I+     I 
Sbjct: 320  LPSEKRRNATALYNPMTVRQLTQKFPTIPWLEYFSTLL-PSSITVTEDEMVIVNVPSFIT 378

Query: 948  SLNQLLKNTPKRVQANYMFWKVFFDSITYMSDD-------YVEVIS-RTDRETL---CKE 1094
             L +LL+ TPKR+QANY+ W+    S++Y++D+       Y  VIS RT+RE     C +
Sbjct: 379  DLEKLLEQTPKRIQANYVMWRAAATSVSYLNDEIRKRQLAYSTVISGRTEREPRWKECVD 438

Query: 1095 KVMNNFQIAVGALYIRKYFNINSREGAIRLLSDIKRQFPRQISGGPEAM--ALRTHIKEV 1268
             V  +F I+VGALY+RKYFN ++++ A+ ++S+I+ +F ++I    + M    R    + 
Sbjct: 439  IVSGSFSISVGALYVRKYFNEDAKKNAVEMVSNIRGEF-KKILDQVDWMDDETRKAALDK 497

Query: 1269 FSTMKTIVGYPDDLMNDTVLEEYYNELEISKGSFLSSSLNLTRHG-----EQRKRVYDPE 1433
              +M T + YPD+L++DT LE++Y +LEI+ G++L S LNLT  G     E+ ++  +  
Sbjct: 498  ADSMSTHIAYPDELLDDTKLEQFYEKLEITPGNYLESILNLTLFGTQYSFEKLRKPVNKS 557

Query: 1434 DWANNQEFLLTPNAAYNLVLKSVEISTALLQSPFYGSKNPAYMNYGGMGFVVGHELAHAL 1613
            DW  +    +  NA Y+ +  S++    +LQ  F+ +  P YMNYG +GFV+GHE+ H  
Sbjct: 558  DWVTHGRPAIV-NAFYSSIENSIQFPAGILQGAFFSNDRPKYMNYGAIGFVMGHEITHGF 616

Query: 1614 -----------YLDEGVMAHEEERF----KCILKQYSKH 1685
                        L E   A  +E++    +CI+ QY  +
Sbjct: 617  DDQGRQFDKNGNLVEWWAAETKEKYLKRAQCIINQYGNY 655


>ref|XP_011494889.1| PREDICTED: membrane metallo-endopeptidase-like 1 isoform X2
            [Ceratosolen solmsi marchali]
          Length = 763

 Score =  303 bits (777), Expect = 3e-90
 Identities = 190/580 (32%), Positives = 313/580 (53%), Gaps = 47/580 (8%)
 Frame = +3

Query: 87   RIEKTLPSSDVACTPCNSKECQDLSNYFDGNMNEEIDPCEDFYEFACGNFSKNAVLDKDT 266
            +I + L + D+  TP     C   ++    NM+  ++PC+DFY FACGNF KN V+  D 
Sbjct: 74   QIVEKLINEDICLTP----GCIHTASLILENMDTSVEPCDDFYRFACGNFLKNTVIPDDK 129

Query: 267  LMESTFTLAGQRIKDKIFNDLEHHKNPYKLKTFDKVKIFYENCKNEKKGNTDGVDYFLEQ 446
               +TF++   +++ ++ + +E   N    + F  VK  Y++C N+ K    G+D   + 
Sbjct: 130  TSVNTFSIISDKLQKQLRSSIEEESNINDPRPFRLVKTLYKSCMNKSKIEEQGLDPLHKI 189

Query: 447  AKEFGGWPLLAGNKWNEDNFEWISLLSKMRSRGFKINYPYTITM------ATLPVISAPS 608
             KE GGWP+L G+ W + NF W   + K R  G+ ++Y    ++      +T  VI    
Sbjct: 190  LKELGGWPVLMGDNWIDSNFNWKESVYKFRRMGYSVDYFLDFSIGIDLKNSTKRVIDLDQ 249

Query: 609  VNKYLELA-AATGKVNKIVRAYYSKMVSLAVMLGADEEVAINEMMEVLAFELKLMKLKVI 785
             +  L     + G  +KIV+AYY  MV +A +LGAD + A+ E+ + L FE+KL  + + 
Sbjct: 250  ASLGLSREYLSKGFNDKIVKAYYIYMVDIAEILGADRQYAMKELKDSLEFEIKLANISLP 309

Query: 786  YE---GTKSLVN-VKVKHLSMIYPTTDWVKLFNTLSNPYDNYFEKDTDIILTNVKLIVSL 953
             E      +L N + V+ L   +PT  W++ FNTL  P  +  E D  +I+     I  L
Sbjct: 310  SEKRRNATALYNLMTVRELDKNFPTIPWLEYFNTLLLPGISITE-DEQVIVNVPSFISDL 368

Query: 954  NQLLKNTPKRVQANYMFWKVFFDSITYMSDD-------YVEVIS-RTDRETL---CKEKV 1100
             +LL+ T KRVQANY+ ++    S++Y++DD       Y  V++ +T+RE     C E V
Sbjct: 369  ERLLQQTSKRVQANYIMFRAAASSVSYLTDDIRKVQLAYSTVVNGKTEREPRWKECVEIV 428

Query: 1101 MNNFQIAVGALYIRKYFNINSREGAIRLLSDIKRQFP---RQISGGPEAMALRTHIKEVF 1271
              +F I++GALY+RKYF  ++++ A+ ++SDI++QF    + +    EA       K V 
Sbjct: 429  SGSFSISIGALYVRKYFKDDAKKNAVEMVSDIRQQFMKILKMVDWMDEATRKSALDKAV- 487

Query: 1272 STMKTIVGYPDDLMNDTVLEEYYNELEISKGSFLSSSLNLTRHG-----EQRKRVYDPED 1436
             +M T + YPD+L++D  LE++Y +LEI+ G++L S LNLT  G     E+ ++  +  D
Sbjct: 488  -SMSTHIAYPDELLDDKKLEKFYKKLEITPGNYLQSILNLTLFGTEYSFEKLRKPVNKSD 546

Query: 1437 W-ANNQEFLLTPNAAYNLVLKSVEISTALLQSPFYGSKNPAYMNYGGMGFVVGHELAHAL 1613
            W A+ +  ++  NA Y+ +  S++    +LQ  F+ +  P YMNYG +GFV+GHE+ H  
Sbjct: 547  WIAHGRPAIV--NAFYSSIENSIQFPAGILQGAFFSNDRPRYMNYGAIGFVMGHEITHG- 603

Query: 1614 YLDEGVMAHEE----------------ERFKCILKQYSKH 1685
            + D+G    +E                +R +CI+ QY  +
Sbjct: 604  FDDQGRQFDKEGNLVEWWAKETKERYLKRAECIIHQYGNY 643


>ref|XP_008208160.1| PREDICTED: membrane metallo-endopeptidase-like 1 isoform X2 [Nasonia
            vitripennis]
          Length = 819

 Score =  304 bits (778), Expect = 7e-90
 Identities = 186/579 (32%), Positives = 314/579 (54%), Gaps = 47/579 (8%)
 Frame = +3

Query: 90   IEKTLPSSDVACTPCNSKECQDLSNYFDGNMNEEIDPCEDFYEFACGNFSKNAVLDKDTL 269
            +EK+ P  D+    C S  C   ++    NM++ ++PC+DFY FACG+F KN ++  D  
Sbjct: 132  VEKS-PEGDI----CLSPGCIHTASSILENMDQNVEPCDDFYRFACGSFLKNTIIPDDKT 186

Query: 270  MESTFTLAGQRIKDKIFNDLEHHKNPYKLKTFDKVKIFYENCKNEKKGNTDGVDYFLEQA 449
              +TF++   +++ ++ + +E    P   + F  +K  Y+ C N+     +G++   +  
Sbjct: 187  SVNTFSIISDKLQKQLRSSIEEESKPNDPRPFRLLKTLYKTCMNKTLIEEEGLNPLHKIL 246

Query: 450  KEFGGWPLLAGNKWNEDNFEWISLLSKMRSRGFKINYPYTITMATLPVISAPSVNKYLEL 629
            KE GGWP+L G+KW++ +F W   + K   +G+ ++Y    ++    V    S  + ++L
Sbjct: 247  KELGGWPVLVGDKWSDGDFNWKESVYKFGKKGYSVDYFIDFSIG---VDLKNSTKRVIDL 303

Query: 630  AAAT----------GKVNKIVRAYYSKMVSLAVMLGADEEVAINEMMEVLAFELKLMKLK 779
              A+          G  +KIV AYY+ MV +A +LGAD E A  E+ E L FE+KL  + 
Sbjct: 304  DQASLGLSREYLSKGMDDKIVSAYYNYMVDIAEILGADREQAKIELKESLEFEIKLANIS 363

Query: 780  VIYE---GTKSLVN-VKVKHLSMIYPTTDWVKLFNTLSNPYDNYFEKDTDIILTNVKLIV 947
            +  E      +L N + V+ L+  +PT  W++ F+TL  P      +D  +I+     I 
Sbjct: 364  LPSEKRRNATALYNPMTVRQLTQKFPTIPWLEYFSTLL-PSSITVTEDEMVIVNVPSFIT 422

Query: 948  SLNQLLKNTPKRVQANYMFWKVFFDSITYMSDD-------YVEVIS-RTDRETL---CKE 1094
             L +LL+ TPKR+QANY+ W+    S++Y++D+       Y  VIS RT+RE     C +
Sbjct: 423  DLEKLLEQTPKRIQANYVMWRAAATSVSYLNDEIRKRQLAYSTVISGRTEREPRWKECVD 482

Query: 1095 KVMNNFQIAVGALYIRKYFNINSREGAIRLLSDIKRQFPRQISGGPEAM--ALRTHIKEV 1268
             V  +F I+VGALY+RKYFN ++++ A+ ++S+I+ +F ++I    + M    R    + 
Sbjct: 483  IVSGSFSISVGALYVRKYFNEDAKKNAVEMVSNIRGEF-KKILDQVDWMDDETRKAALDK 541

Query: 1269 FSTMKTIVGYPDDLMNDTVLEEYYNELEISKGSFLSSSLNLTRHG-----EQRKRVYDPE 1433
              +M T + YPD+L++DT LE++Y +LEI+ G++L S LNLT  G     E+ ++  +  
Sbjct: 542  ADSMSTHIAYPDELLDDTKLEQFYEKLEITPGNYLESILNLTLFGTQYSFEKLRKPVNKS 601

Query: 1434 DWANNQEFLLTPNAAYNLVLKSVEISTALLQSPFYGSKNPAYMNYGGMGFVVGHELAHAL 1613
            DW  +    +  NA Y+ +  S++    +LQ  F+ +  P YMNYG +GFV+GHE+ H  
Sbjct: 602  DWVTHGRPAIV-NAFYSSIENSIQFPAGILQGAFFSNDRPKYMNYGAIGFVMGHEITHGF 660

Query: 1614 -----------YLDEGVMAHEEERF----KCILKQYSKH 1685
                        L E   A  +E++    +CI+ QY  +
Sbjct: 661  DDQGRQFDKNGNLVEWWAAETKEKYLKRAQCIINQYGNY 699


>ref|XP_008208159.1| PREDICTED: membrane metallo-endopeptidase-like 1 isoform X1 [Nasonia
            vitripennis]
          Length = 830

 Score =  304 bits (778), Expect = 8e-90
 Identities = 186/579 (32%), Positives = 314/579 (54%), Gaps = 47/579 (8%)
 Frame = +3

Query: 90   IEKTLPSSDVACTPCNSKECQDLSNYFDGNMNEEIDPCEDFYEFACGNFSKNAVLDKDTL 269
            +EK+ P  D+    C S  C   ++    NM++ ++PC+DFY FACG+F KN ++  D  
Sbjct: 143  VEKS-PEGDI----CLSPGCIHTASSILENMDQNVEPCDDFYRFACGSFLKNTIIPDDKT 197

Query: 270  MESTFTLAGQRIKDKIFNDLEHHKNPYKLKTFDKVKIFYENCKNEKKGNTDGVDYFLEQA 449
              +TF++   +++ ++ + +E    P   + F  +K  Y+ C N+     +G++   +  
Sbjct: 198  SVNTFSIISDKLQKQLRSSIEEESKPNDPRPFRLLKTLYKTCMNKTLIEEEGLNPLHKIL 257

Query: 450  KEFGGWPLLAGNKWNEDNFEWISLLSKMRSRGFKINYPYTITMATLPVISAPSVNKYLEL 629
            KE GGWP+L G+KW++ +F W   + K   +G+ ++Y    ++    V    S  + ++L
Sbjct: 258  KELGGWPVLVGDKWSDGDFNWKESVYKFGKKGYSVDYFIDFSIG---VDLKNSTKRVIDL 314

Query: 630  AAAT----------GKVNKIVRAYYSKMVSLAVMLGADEEVAINEMMEVLAFELKLMKLK 779
              A+          G  +KIV AYY+ MV +A +LGAD E A  E+ E L FE+KL  + 
Sbjct: 315  DQASLGLSREYLSKGMDDKIVSAYYNYMVDIAEILGADREQAKIELKESLEFEIKLANIS 374

Query: 780  VIYE---GTKSLVN-VKVKHLSMIYPTTDWVKLFNTLSNPYDNYFEKDTDIILTNVKLIV 947
            +  E      +L N + V+ L+  +PT  W++ F+TL  P      +D  +I+     I 
Sbjct: 375  LPSEKRRNATALYNPMTVRQLTQKFPTIPWLEYFSTLL-PSSITVTEDEMVIVNVPSFIT 433

Query: 948  SLNQLLKNTPKRVQANYMFWKVFFDSITYMSDD-------YVEVIS-RTDRETL---CKE 1094
             L +LL+ TPKR+QANY+ W+    S++Y++D+       Y  VIS RT+RE     C +
Sbjct: 434  DLEKLLEQTPKRIQANYVMWRAAATSVSYLNDEIRKRQLAYSTVISGRTEREPRWKECVD 493

Query: 1095 KVMNNFQIAVGALYIRKYFNINSREGAIRLLSDIKRQFPRQISGGPEAM--ALRTHIKEV 1268
             V  +F I+VGALY+RKYFN ++++ A+ ++S+I+ +F ++I    + M    R    + 
Sbjct: 494  IVSGSFSISVGALYVRKYFNEDAKKNAVEMVSNIRGEF-KKILDQVDWMDDETRKAALDK 552

Query: 1269 FSTMKTIVGYPDDLMNDTVLEEYYNELEISKGSFLSSSLNLTRHG-----EQRKRVYDPE 1433
              +M T + YPD+L++DT LE++Y +LEI+ G++L S LNLT  G     E+ ++  +  
Sbjct: 553  ADSMSTHIAYPDELLDDTKLEQFYEKLEITPGNYLESILNLTLFGTQYSFEKLRKPVNKS 612

Query: 1434 DWANNQEFLLTPNAAYNLVLKSVEISTALLQSPFYGSKNPAYMNYGGMGFVVGHELAHAL 1613
            DW  +    +  NA Y+ +  S++    +LQ  F+ +  P YMNYG +GFV+GHE+ H  
Sbjct: 613  DWVTHGRPAIV-NAFYSSIENSIQFPAGILQGAFFSNDRPKYMNYGAIGFVMGHEITHGF 671

Query: 1614 -----------YLDEGVMAHEEERF----KCILKQYSKH 1685
                        L E   A  +E++    +CI+ QY  +
Sbjct: 672  DDQGRQFDKNGNLVEWWAAETKEKYLKRAQCIINQYGNY 710


>ref|XP_016836925.1| PREDICTED: neprilysin-11-like [Nasonia vitripennis]
          Length = 779

 Score =  301 bits (771), Expect = 3e-89
 Identities = 160/526 (30%), Positives = 278/526 (52%), Gaps = 34/526 (6%)
 Frame = +3

Query: 132  CNSKECQDLSNYFDGNMNEEIDPCEDFYEFACGNFSKNAVLDKDTLMESTFTLAGQRIKD 311
            C+S  CQ+ +++F  N+++ IDPCEDFY+FACGNF KNA++  D       ++  +++  
Sbjct: 99   CSSLSCQNEASFFINNIDQNIDPCEDFYQFACGNFIKNAIIPDDENKIDMMSITQKKVLS 158

Query: 312  KIFNDLEHHKNPYKLKTFDKVKIFYENCKNEKKGNTDGVDYFLEQAKEFGGWPLLAGNKW 491
            ++ ++++    P ++  F K+KI+Y NC N+ +   +G    L    E G WP+L G  W
Sbjct: 159  ELVDEIKKEIQPNEISAFKKLKIYYHNCMNKSRIQEEGTYTLLRILDELGDWPVLLGESW 218

Query: 492  NEDNFEWISLLSKMRSRGFKINYPYTITMATLPVISAPSVNKYLELAAAT-------GKV 650
             ++N+ W  ++ +++  G+ + +P T  +   P  +  ++ K L             G  
Sbjct: 219  TDNNYNWPEIVFRIKDHGYPVLFPVTFYVGIDPKNTTKNILKILGATTRVSPTYLLDGPS 278

Query: 651  NKIVRAYYSKMVSLAVMLGADEEVAINEMMEVLAFELKLMKLKVIYEGTKSLVNVKVKH- 827
             KI  AYY  MV +AVMLGAD++ A  +M + L FE++L     I    + L+N+   H 
Sbjct: 279  GKIPNAYYDYMVDIAVMLGADKDFATKDMQKCLDFEVELFN---IQSSLEILMNITATHN 335

Query: 828  ------LSMIYPTTDWVKLFNTLSNPYDNYFEKDTDIILTNVKLIVSLNQLLKNTPKRVQ 989
                  LS  YP+  W++L + + N  +   +++  +I+ ++     + +L+  TPKRV 
Sbjct: 336  PITIIGLSEKYPSIPWLELISEVLNLSNVSVDENEVVIVNDLNFFSKIEKLIARTPKRVI 395

Query: 990  ANYMFWKVFFDSITYMSDDYVE-----------VISRTDRETLCKEKVMNNFQIAVGALY 1136
            ANY+ W+V +DSI Y+ D +++           V  R  R   C + VM  F I++ ALY
Sbjct: 396  ANYLIWQVVYDSIDYLPDAFLDRKLMFSRVVRGVKERKHRSYSCIQDVMEGFSISLSALY 455

Query: 1137 IRKYFNINSREGAIRLLSDIKRQFPRQISGGPEAMALRTHIKEV----FSTMKTIVGYPD 1304
            +R+YFN   +E  + L+ ++K QF + +    E   +    KE        M   VGY D
Sbjct: 456  VRRYFNKEIQENVLALVQNVKNQFRKMLE---EVDWMDNDTKETALDKIDAMDVFVGYSD 512

Query: 1305 DLMNDTVLEEYYNELEISKGSFLSSSLNLT-----RHGEQRKRVYDPEDWANNQEFLLTP 1469
            +L +D  +++YY +L+I+ GS+L S+ N++     ++    +   + +DW +N+   +  
Sbjct: 513  ELFDDLKIDKYYEDLDINYGSYLKSAFNISLFFTKQYYASLRGPVNKKDWKDNKNAAII- 571

Query: 1470 NAAYNLVLKSVEISTALLQSPFYGSKNPAYMNYGGMGFVVGHELAH 1607
            NA Y L   + EI    L+  FY    P Y+NYG +G ++GHE+ H
Sbjct: 572  NAYYYLQKNTFEIPAGFLRGSFYRYDRPKYLNYGAIGSIIGHEITH 617


>ref|XP_011312064.1| PREDICTED: membrane metallo-endopeptidase-like 1 isoform X2 [Fopius
            arisanus]
          Length = 763

 Score =  299 bits (766), Expect = 1e-88
 Identities = 181/568 (31%), Positives = 305/568 (53%), Gaps = 50/568 (8%)
 Frame = +3

Query: 132  CNSKECQDLSNYFDGNMNEEIDPCEDFYEFACGNFSKNAVLDKDTLMESTFTLAGQRIKD 311
            C +  C   ++    NM+E+++PC+DFY+FACG F KN ++  D +  ++F++   ++++
Sbjct: 85   CTTPACIHAASKVLNNMDEDVEPCDDFYKFACGGFLKNTLIPDDKVSVNSFSVISDKVQE 144

Query: 312  KIFNDLEHHKNPYKLKTFDKVKIFYENCKNEKKGNTDGVDYFLEQAKEFGGWPLLAGNKW 491
            ++   +E    P + K F   K  Y+ C N+      G+   L   ++ GGWP+L G+ W
Sbjct: 145  QLRISIEEPSYPMEPKPFKLAKNLYKACMNKTAIEAQGLTPLLNILRKLGGWPVLDGDMW 204

Query: 492  NEDNFEWISLLSKMRSRGFKINYPYTITMATLPVISAPSVNKYLELAAAT---------- 641
            NE++F+WI  + K R  G+ ++Y    ++    V    S  + ++L  A+          
Sbjct: 205  NEESFDWIESVYKFRDSGYSVDYFLDFSIG---VDLKNSTKRVIDLDQASLGLSREYLSK 261

Query: 642  GKVNKIVRAYYSKMVSLAVMLGADEEVAINEMMEVLAFELKLMKLKVIYEGTKS---LVN 812
            G  +KIV+AYY+ MV +AV+LGA  E+A  +++  L FE++L  + +  E  ++   L N
Sbjct: 262  GLDDKIVKAYYNYMVDIAVILGAKRELAAKQLLSSLKFEIQLANISLPNEKRRNATLLYN 321

Query: 813  -VKVKHLSMIYPTTDWVKLFNTLSNPYDNYFEKDTDIILTNV-KLIVSLNQLLKNTPKRV 986
             + V  LS  YP+  W + FN L  P  +    D +I + NV   I SL +L++ TPKR+
Sbjct: 322  PMTVAELSKTYPSIPWKEYFNRLLPP--SLQVDDNEIAIVNVPSFISSLEKLMRETPKRI 379

Query: 987  QANYMFWKVFFDSITYMSDD-------YVEVIS-RTDRETL---CKEKVMNNFQIAVGAL 1133
            QANY+ W+    S++Y +D+       Y   +S RT+RE+    C + V  +  I+VGA 
Sbjct: 380  QANYVMWRATAASVSYANDEIRKRQLQYSTALSGRTERESRWKECVDLVGGSLSISVGAQ 439

Query: 1134 YIRKYFNINSREGAIRLLSDIKRQFP---RQISGGPEAMALRTHIKEVFSTMKTIVGYPD 1304
            YIRKYFN  +++ AI +++DIK+QF     +I    E    R    E  ++M + + YPD
Sbjct: 440  YIRKYFNEEAKKNAIEMVNDIKKQFNYILEKIDWMDE--ETRKSALEKAASMTSHIAYPD 497

Query: 1305 DLMNDTVLEEYYNELEISKGSFLSSSLNLTRHG-----EQRKRVYDPEDWANNQEFLLTP 1469
            +L++D+ LEE+Y +LE+S  ++L   LNLT  G      + ++  +  DW  +    +  
Sbjct: 498  ELLDDSKLEEFYQDLELSDENYLQGILNLTLFGTEYSFSKLRKPVNKSDWVTHGRPAVV- 556

Query: 1470 NAAYNLVLKSVEISTALLQSPFYGSKNPAYMNYGGMGFVVGHELAHALYLDEGVMAHEE- 1646
            NA Y+ +  S++    +LQ  FY +  P YMNYG +GFV+GHE+ H  + D+G    +E 
Sbjct: 557  NAFYSSIENSIQFPAGILQDSFYSNDRPRYMNYGAIGFVIGHEITHG-FDDQGRQFDKEG 615

Query: 1647 ---------------ERFKCILKQYSKH 1685
                            + +CI+ QY  +
Sbjct: 616  NLVDWWAPSTKEKYLAKAECIINQYGNY 643


>ref|XP_011312063.1| PREDICTED: membrane metallo-endopeptidase-like 1 isoform X1 [Fopius
            arisanus]
          Length = 774

 Score =  299 bits (766), Expect = 2e-88
 Identities = 181/568 (31%), Positives = 305/568 (53%), Gaps = 50/568 (8%)
 Frame = +3

Query: 132  CNSKECQDLSNYFDGNMNEEIDPCEDFYEFACGNFSKNAVLDKDTLMESTFTLAGQRIKD 311
            C +  C   ++    NM+E+++PC+DFY+FACG F KN ++  D +  ++F++   ++++
Sbjct: 96   CTTPACIHAASKVLNNMDEDVEPCDDFYKFACGGFLKNTLIPDDKVSVNSFSVISDKVQE 155

Query: 312  KIFNDLEHHKNPYKLKTFDKVKIFYENCKNEKKGNTDGVDYFLEQAKEFGGWPLLAGNKW 491
            ++   +E    P + K F   K  Y+ C N+      G+   L   ++ GGWP+L G+ W
Sbjct: 156  QLRISIEEPSYPMEPKPFKLAKNLYKACMNKTAIEAQGLTPLLNILRKLGGWPVLDGDMW 215

Query: 492  NEDNFEWISLLSKMRSRGFKINYPYTITMATLPVISAPSVNKYLELAAAT---------- 641
            NE++F+WI  + K R  G+ ++Y    ++    V    S  + ++L  A+          
Sbjct: 216  NEESFDWIESVYKFRDSGYSVDYFLDFSIG---VDLKNSTKRVIDLDQASLGLSREYLSK 272

Query: 642  GKVNKIVRAYYSKMVSLAVMLGADEEVAINEMMEVLAFELKLMKLKVIYEGTKS---LVN 812
            G  +KIV+AYY+ MV +AV+LGA  E+A  +++  L FE++L  + +  E  ++   L N
Sbjct: 273  GLDDKIVKAYYNYMVDIAVILGAKRELAAKQLLSSLKFEIQLANISLPNEKRRNATLLYN 332

Query: 813  -VKVKHLSMIYPTTDWVKLFNTLSNPYDNYFEKDTDIILTNV-KLIVSLNQLLKNTPKRV 986
             + V  LS  YP+  W + FN L  P  +    D +I + NV   I SL +L++ TPKR+
Sbjct: 333  PMTVAELSKTYPSIPWKEYFNRLLPP--SLQVDDNEIAIVNVPSFISSLEKLMRETPKRI 390

Query: 987  QANYMFWKVFFDSITYMSDD-------YVEVIS-RTDRETL---CKEKVMNNFQIAVGAL 1133
            QANY+ W+    S++Y +D+       Y   +S RT+RE+    C + V  +  I+VGA 
Sbjct: 391  QANYVMWRATAASVSYANDEIRKRQLQYSTALSGRTERESRWKECVDLVGGSLSISVGAQ 450

Query: 1134 YIRKYFNINSREGAIRLLSDIKRQFP---RQISGGPEAMALRTHIKEVFSTMKTIVGYPD 1304
            YIRKYFN  +++ AI +++DIK+QF     +I    E    R    E  ++M + + YPD
Sbjct: 451  YIRKYFNEEAKKNAIEMVNDIKKQFNYILEKIDWMDE--ETRKSALEKAASMTSHIAYPD 508

Query: 1305 DLMNDTVLEEYYNELEISKGSFLSSSLNLTRHG-----EQRKRVYDPEDWANNQEFLLTP 1469
            +L++D+ LEE+Y +LE+S  ++L   LNLT  G      + ++  +  DW  +    +  
Sbjct: 509  ELLDDSKLEEFYQDLELSDENYLQGILNLTLFGTEYSFSKLRKPVNKSDWVTHGRPAVV- 567

Query: 1470 NAAYNLVLKSVEISTALLQSPFYGSKNPAYMNYGGMGFVVGHELAHALYLDEGVMAHEE- 1646
            NA Y+ +  S++    +LQ  FY +  P YMNYG +GFV+GHE+ H  + D+G    +E 
Sbjct: 568  NAFYSSIENSIQFPAGILQDSFYSNDRPRYMNYGAIGFVIGHEITHG-FDDQGRQFDKEG 626

Query: 1647 ---------------ERFKCILKQYSKH 1685
                            + +CI+ QY  +
Sbjct: 627  NLVDWWAPSTKEKYLAKAECIINQYGNY 654


>ref|XP_014366580.1| PREDICTED: neprilysin-11 isoform X2 [Papilio machaon]
          Length = 728

 Score =  298 bits (763), Expect = 2e-88
 Identities = 195/595 (32%), Positives = 314/595 (52%), Gaps = 54/595 (9%)
 Frame = +3

Query: 63   YSPESNEVRIE--KTLP----SSDVACTPCNSKECQDLSNYFDGNMNEEIDPCEDFYEFA 224
            Y P+++E+RI   +++P     SD     C S  C   ++    NM++ +DPC+DFYEF+
Sbjct: 22   YLPQTSEMRISSPQSMPPAVFGSDYEI--CYSPGCVHTASKLLSNMDQNVDPCDDFYEFS 79

Query: 225  CGNFSKNAVLDKDTLMESTFTLAGQRIKDKIFNDLEHHKNPYKLKTFDKVKIFYENCKNE 404
            CG+F KN  +  D    +TF++   +++++I   LE      +   F   K  Y+ C N+
Sbjct: 80   CGSFEKNTRIPDDKSSVNTFSIITDQLQEQIRALLEEPITEGEPHPFILAKTLYKACMNK 139

Query: 405  KKGNTDGVDYFLEQAKEFGGWPLLAGNKWNEDNFEWISLLSKMRSRGFKINYPYTITMAT 584
                  GV   L+  K FGGWP+L G+ WNE  F W   + + R+ G+ ++Y    +++ 
Sbjct: 140  SVIEARGVKPLLDIMKRFGGWPVLEGDNWNEHAFAWDDSVYRFRTAGYSVDYFLDFSIS- 198

Query: 585  LPVISAPSVNKYLELAAAT----------GKVNKIVRAYYSKMVSLAVMLGADEEVAINE 734
              V    S  + ++L  A+          G  +K+V+AYYS MV ++V+LGAD + A  E
Sbjct: 199  --VDVKNSTKRIIDLDQASLGLSREYLSHGFNDKLVQAYYSYMVDISVLLGADRKRAETE 256

Query: 735  MMEVLAFELKLMKLKVIYE---GTKSLVN-VKVKHLSMIYPTTDWVKLFNTLSNPYDNYF 902
            + E L FE+ L  + +  E      +L N + V  L   +P  DW+K  N L  P+ +  
Sbjct: 257  LRESLDFEITLANISLPLEKRRNATALYNPMTVTQLQKRFPKVDWMKYINRLLAPHVS-I 315

Query: 903  EKDTDIILTNVKLIVSLNQLLKNTPKRVQANYMFWKVFFDSITYMSDD-------YVEVI 1061
            + D  +I+     I SL Q L++TPKRVQANY+ W+V   S++Y++D+       YV V+
Sbjct: 316  DMDEVVIVNVPSYITSLEQFLESTPKRVQANYVMWRVAGASVSYLTDELRRRQLSYVTVL 375

Query: 1062 S-RTDRETLCKEKV---MNNFQIAVGALYIRKYFNINSREGAIRLLSDIKRQFPRQISGG 1229
            S +T+RE+  KE V     +  I+VGALYIRKYFN +S++ A+ ++ DI+ QF R +   
Sbjct: 376  SGKTERESRWKECVDTTSMSLSISVGALYIRKYFNEDSKKNALEMVKDIREQFRRTLE-E 434

Query: 1230 PEAM--ALRTHIKEVFSTMKTIVGYPDDLMNDTVLEEYYNELEISKGSFLSSSLNLTRHG 1403
             E M    R         M   + YPD+++ND  L E+Y  LE+S+   + S LNLT  G
Sbjct: 435  VEWMDDTTRRAALAKADAMAAHIAYPDEMLNDEKLSEFYEGLEMSEDKLMESVLNLTLFG 494

Query: 1404 -----EQRKRVYDPEDWANNQEFLLTPNAAYNLVLKSVEISTALLQSPFYGSKNPAYMNY 1568
                 ++ ++  +  DW  +    +  NA Y+ +  S++    +LQ  F+ +  PAYMNY
Sbjct: 495  TDYLFQKLRQPVNKTDWVTHGRPAIV-NAFYSSIENSIQFPAGILQGAFFSALRPAYMNY 553

Query: 1569 GGMGFVVGHELAHALYLDEGVMAHEE----------------ERFKCILKQYSKH 1685
            G +GFV+GHE+ H  + D+G    ++                ++ KCI+ QYS +
Sbjct: 554  GAIGFVIGHEITHG-FDDQGRQFDKDGNLVDWWQEETKQKYLKKAKCIIDQYSNY 607


>ref|XP_015173767.1| PREDICTED: membrane metallo-endopeptidase-like 1 isoform X3 [Polistes
            dominula]
          Length = 760

 Score =  299 bits (765), Expect = 2e-88
 Identities = 177/563 (31%), Positives = 303/563 (53%), Gaps = 45/563 (7%)
 Frame = +3

Query: 132  CNSKECQDLSNYFDGNMNEEIDPCEDFYEFACGNFSKNAVLDKDTLMESTFTLAGQRIKD 311
            C S  C   ++    NM+ +++PC+DFY+FACG F K+ ++  D    +TF++    ++ 
Sbjct: 82   CVSPGCVHTASKILENMDSDVEPCDDFYQFACGGFLKSTIIPDDKTSVNTFSIISDNLQQ 141

Query: 312  KIFNDLEHHKNPYKLKTFDKVKIFYENCKNEKKGNTDGVDYFLEQAKEFGGWPLLAGNKW 491
            ++   +E    P + K F   KIFY+ C N+      G++      K  GGWP+L G+ W
Sbjct: 142  QLRTSIEEKSPPNEPKPFTLAKIFYKTCMNKTAIEERGLEPLHNILKTLGGWPVLEGDNW 201

Query: 492  NEDNFEWISLLSKMRSRGFKINYPYTITM------ATLPVISAPSVNKYLELA-AATGKV 650
             E++F WI  + K R++G+ ++Y    ++      +T+ +I     +  L     + G  
Sbjct: 202  KEEDFNWIDSVYKFRTKGYSVDYFIDFSIGVDLKNSTMRIIDLDQASLGLSREYLSKGFD 261

Query: 651  NKIVRAYYSKMVSLAVMLGADEEVAINEMMEVLAFELKLMKLKVIYEGTKS---LVN-VK 818
            +KIV+AYY  MV +AV+LGAD+  A  E+ E L FE+KL  + +  E  ++   L N + 
Sbjct: 262  DKIVQAYYDYMVDIAVILGADKNRAKTELKESLEFEMKLANISLPNEKRRNATLLYNPMT 321

Query: 819  VKHLSMIYPTTDWVKLFNTLSNPYDNYFEKDTDIILTNVKLIVSLNQLLKNTPKRVQANY 998
            +  L+  +P+  W + FNT+  P     E +  +I++    I SL +LL  TPKR+QANY
Sbjct: 322  ITELNKNFPSIPWKEYFNTILAPTVQVDENEV-VIVSVPSYITSLEELLSKTPKRIQANY 380

Query: 999  MFWKVFFDSITYMSDD-------YVEVIS-RTDRETL---CKEKVMNNFQIAVGALYIRK 1145
            + W+    S++Y++++       Y   +S +T+RE     C + V  +  I+VGA+Y+RK
Sbjct: 381  VMWRAAAGSVSYLTENIRRRQLQYSTALSGKTEREARWKECVDIVSGSLSISVGAMYVRK 440

Query: 1146 YFNINSREGAIRLLSDIKRQFPRQISGGPEAMALRT--HIKEVFSTMKTIVGYPDDLMND 1319
            YF  ++++ AI ++SDI+ +F ++I    + M   T     +   +M + + YPD+L++D
Sbjct: 441  YFKEDAKKNAIEMVSDIREEF-KKILKKVDWMDENTKESALDKAESMSSHIAYPDELLDD 499

Query: 1320 TVLEEYYNELEISKGSFLSSSLNLTRHG-----EQRKRVYDPEDWANNQEFLLTPNAAYN 1484
              LEE+Y +LE++ GS+L S LNLT  G      + ++  +  DW  +    +  NA Y+
Sbjct: 500  KKLEEFYKKLELTDGSYLESILNLTLFGTEYSFSKLRKPVNKSDWVTHGRPAIV-NAFYS 558

Query: 1485 LVLKSVEISTALLQSPFYGSKNPAYMNYGGMGFVVGHELAHALYLDEGVMAHEE------ 1646
             +  S++    +LQ  F+ +  P YMNYG +GFV+GHE+ H  + D+G    +E      
Sbjct: 559  SIENSIQFPAGILQGTFFNNDRPRYMNYGAIGFVIGHEITHG-FDDQGRQFDKEGNLVDW 617

Query: 1647 ----------ERFKCILKQYSKH 1685
                      ER +CI+ QY  +
Sbjct: 618  WAPETKENYLERAECIVHQYGNY 640


>ref|XP_015173766.1| PREDICTED: neprilysin isoform X2 [Polistes dominula]
          Length = 766

 Score =  299 bits (765), Expect = 2e-88
 Identities = 177/563 (31%), Positives = 303/563 (53%), Gaps = 45/563 (7%)
 Frame = +3

Query: 132  CNSKECQDLSNYFDGNMNEEIDPCEDFYEFACGNFSKNAVLDKDTLMESTFTLAGQRIKD 311
            C S  C   ++    NM+ +++PC+DFY+FACG F K+ ++  D    +TF++    ++ 
Sbjct: 88   CVSPGCVHTASKILENMDSDVEPCDDFYQFACGGFLKSTIIPDDKTSVNTFSIISDNLQQ 147

Query: 312  KIFNDLEHHKNPYKLKTFDKVKIFYENCKNEKKGNTDGVDYFLEQAKEFGGWPLLAGNKW 491
            ++   +E    P + K F   KIFY+ C N+      G++      K  GGWP+L G+ W
Sbjct: 148  QLRTSIEEKSPPNEPKPFTLAKIFYKTCMNKTAIEERGLEPLHNILKTLGGWPVLEGDNW 207

Query: 492  NEDNFEWISLLSKMRSRGFKINYPYTITM------ATLPVISAPSVNKYLELA-AATGKV 650
             E++F WI  + K R++G+ ++Y    ++      +T+ +I     +  L     + G  
Sbjct: 208  KEEDFNWIDSVYKFRTKGYSVDYFIDFSIGVDLKNSTMRIIDLDQASLGLSREYLSKGFD 267

Query: 651  NKIVRAYYSKMVSLAVMLGADEEVAINEMMEVLAFELKLMKLKVIYEGTKS---LVN-VK 818
            +KIV+AYY  MV +AV+LGAD+  A  E+ E L FE+KL  + +  E  ++   L N + 
Sbjct: 268  DKIVQAYYDYMVDIAVILGADKNRAKTELKESLEFEMKLANISLPNEKRRNATLLYNPMT 327

Query: 819  VKHLSMIYPTTDWVKLFNTLSNPYDNYFEKDTDIILTNVKLIVSLNQLLKNTPKRVQANY 998
            +  L+  +P+  W + FNT+  P     E +  +I++    I SL +LL  TPKR+QANY
Sbjct: 328  ITELNKNFPSIPWKEYFNTILAPTVQVDENEV-VIVSVPSYITSLEELLSKTPKRIQANY 386

Query: 999  MFWKVFFDSITYMSDD-------YVEVIS-RTDRETL---CKEKVMNNFQIAVGALYIRK 1145
            + W+    S++Y++++       Y   +S +T+RE     C + V  +  I+VGA+Y+RK
Sbjct: 387  VMWRAAAGSVSYLTENIRRRQLQYSTALSGKTEREARWKECVDIVSGSLSISVGAMYVRK 446

Query: 1146 YFNINSREGAIRLLSDIKRQFPRQISGGPEAMALRT--HIKEVFSTMKTIVGYPDDLMND 1319
            YF  ++++ AI ++SDI+ +F ++I    + M   T     +   +M + + YPD+L++D
Sbjct: 447  YFKEDAKKNAIEMVSDIREEF-KKILKKVDWMDENTKESALDKAESMSSHIAYPDELLDD 505

Query: 1320 TVLEEYYNELEISKGSFLSSSLNLTRHG-----EQRKRVYDPEDWANNQEFLLTPNAAYN 1484
              LEE+Y +LE++ GS+L S LNLT  G      + ++  +  DW  +    +  NA Y+
Sbjct: 506  KKLEEFYKKLELTDGSYLESILNLTLFGTEYSFSKLRKPVNKSDWVTHGRPAIV-NAFYS 564

Query: 1485 LVLKSVEISTALLQSPFYGSKNPAYMNYGGMGFVVGHELAHALYLDEGVMAHEE------ 1646
             +  S++    +LQ  F+ +  P YMNYG +GFV+GHE+ H  + D+G    +E      
Sbjct: 565  SIENSIQFPAGILQGTFFNNDRPRYMNYGAIGFVIGHEITHG-FDDQGRQFDKEGNLVDW 623

Query: 1647 ----------ERFKCILKQYSKH 1685
                      ER +CI+ QY  +
Sbjct: 624  WAPETKENYLERAECIVHQYGNY 646


>ref|XP_015173765.1| PREDICTED: neprilysin isoform X1 [Polistes dominula]
          Length = 771

 Score =  299 bits (765), Expect = 2e-88
 Identities = 177/563 (31%), Positives = 303/563 (53%), Gaps = 45/563 (7%)
 Frame = +3

Query: 132  CNSKECQDLSNYFDGNMNEEIDPCEDFYEFACGNFSKNAVLDKDTLMESTFTLAGQRIKD 311
            C S  C   ++    NM+ +++PC+DFY+FACG F K+ ++  D    +TF++    ++ 
Sbjct: 93   CVSPGCVHTASKILENMDSDVEPCDDFYQFACGGFLKSTIIPDDKTSVNTFSIISDNLQQ 152

Query: 312  KIFNDLEHHKNPYKLKTFDKVKIFYENCKNEKKGNTDGVDYFLEQAKEFGGWPLLAGNKW 491
            ++   +E    P + K F   KIFY+ C N+      G++      K  GGWP+L G+ W
Sbjct: 153  QLRTSIEEKSPPNEPKPFTLAKIFYKTCMNKTAIEERGLEPLHNILKTLGGWPVLEGDNW 212

Query: 492  NEDNFEWISLLSKMRSRGFKINYPYTITM------ATLPVISAPSVNKYLELA-AATGKV 650
             E++F WI  + K R++G+ ++Y    ++      +T+ +I     +  L     + G  
Sbjct: 213  KEEDFNWIDSVYKFRTKGYSVDYFIDFSIGVDLKNSTMRIIDLDQASLGLSREYLSKGFD 272

Query: 651  NKIVRAYYSKMVSLAVMLGADEEVAINEMMEVLAFELKLMKLKVIYEGTKS---LVN-VK 818
            +KIV+AYY  MV +AV+LGAD+  A  E+ E L FE+KL  + +  E  ++   L N + 
Sbjct: 273  DKIVQAYYDYMVDIAVILGADKNRAKTELKESLEFEMKLANISLPNEKRRNATLLYNPMT 332

Query: 819  VKHLSMIYPTTDWVKLFNTLSNPYDNYFEKDTDIILTNVKLIVSLNQLLKNTPKRVQANY 998
            +  L+  +P+  W + FNT+  P     E +  +I++    I SL +LL  TPKR+QANY
Sbjct: 333  ITELNKNFPSIPWKEYFNTILAPTVQVDENEV-VIVSVPSYITSLEELLSKTPKRIQANY 391

Query: 999  MFWKVFFDSITYMSDD-------YVEVIS-RTDRETL---CKEKVMNNFQIAVGALYIRK 1145
            + W+    S++Y++++       Y   +S +T+RE     C + V  +  I+VGA+Y+RK
Sbjct: 392  VMWRAAAGSVSYLTENIRRRQLQYSTALSGKTEREARWKECVDIVSGSLSISVGAMYVRK 451

Query: 1146 YFNINSREGAIRLLSDIKRQFPRQISGGPEAMALRT--HIKEVFSTMKTIVGYPDDLMND 1319
            YF  ++++ AI ++SDI+ +F ++I    + M   T     +   +M + + YPD+L++D
Sbjct: 452  YFKEDAKKNAIEMVSDIREEF-KKILKKVDWMDENTKESALDKAESMSSHIAYPDELLDD 510

Query: 1320 TVLEEYYNELEISKGSFLSSSLNLTRHG-----EQRKRVYDPEDWANNQEFLLTPNAAYN 1484
              LEE+Y +LE++ GS+L S LNLT  G      + ++  +  DW  +    +  NA Y+
Sbjct: 511  KKLEEFYKKLELTDGSYLESILNLTLFGTEYSFSKLRKPVNKSDWVTHGRPAIV-NAFYS 569

Query: 1485 LVLKSVEISTALLQSPFYGSKNPAYMNYGGMGFVVGHELAHALYLDEGVMAHEE------ 1646
             +  S++    +LQ  F+ +  P YMNYG +GFV+GHE+ H  + D+G    +E      
Sbjct: 570  SIENSIQFPAGILQGTFFNNDRPRYMNYGAIGFVIGHEITHG-FDDQGRQFDKEGNLVDW 628

Query: 1647 ----------ERFKCILKQYSKH 1685
                      ER +CI+ QY  +
Sbjct: 629  WAPETKENYLERAECIVHQYGNY 651


>ref|XP_014366579.1| PREDICTED: endothelin-converting enzyme 1 isoform X1 [Papilio
            machaon]
          Length = 790

 Score =  298 bits (763), Expect = 6e-88
 Identities = 195/595 (32%), Positives = 314/595 (52%), Gaps = 54/595 (9%)
 Frame = +3

Query: 63   YSPESNEVRIE--KTLP----SSDVACTPCNSKECQDLSNYFDGNMNEEIDPCEDFYEFA 224
            Y P+++E+RI   +++P     SD     C S  C   ++    NM++ +DPC+DFYEF+
Sbjct: 84   YLPQTSEMRISSPQSMPPAVFGSDYEI--CYSPGCVHTASKLLSNMDQNVDPCDDFYEFS 141

Query: 225  CGNFSKNAVLDKDTLMESTFTLAGQRIKDKIFNDLEHHKNPYKLKTFDKVKIFYENCKNE 404
            CG+F KN  +  D    +TF++   +++++I   LE      +   F   K  Y+ C N+
Sbjct: 142  CGSFEKNTRIPDDKSSVNTFSIITDQLQEQIRALLEEPITEGEPHPFILAKTLYKACMNK 201

Query: 405  KKGNTDGVDYFLEQAKEFGGWPLLAGNKWNEDNFEWISLLSKMRSRGFKINYPYTITMAT 584
                  GV   L+  K FGGWP+L G+ WNE  F W   + + R+ G+ ++Y    +++ 
Sbjct: 202  SVIEARGVKPLLDIMKRFGGWPVLEGDNWNEHAFAWDDSVYRFRTAGYSVDYFLDFSIS- 260

Query: 585  LPVISAPSVNKYLELAAAT----------GKVNKIVRAYYSKMVSLAVMLGADEEVAINE 734
              V    S  + ++L  A+          G  +K+V+AYYS MV ++V+LGAD + A  E
Sbjct: 261  --VDVKNSTKRIIDLDQASLGLSREYLSHGFNDKLVQAYYSYMVDISVLLGADRKRAETE 318

Query: 735  MMEVLAFELKLMKLKVIYE---GTKSLVN-VKVKHLSMIYPTTDWVKLFNTLSNPYDNYF 902
            + E L FE+ L  + +  E      +L N + V  L   +P  DW+K  N L  P+ +  
Sbjct: 319  LRESLDFEITLANISLPLEKRRNATALYNPMTVTQLQKRFPKVDWMKYINRLLAPHVS-I 377

Query: 903  EKDTDIILTNVKLIVSLNQLLKNTPKRVQANYMFWKVFFDSITYMSDD-------YVEVI 1061
            + D  +I+     I SL Q L++TPKRVQANY+ W+V   S++Y++D+       YV V+
Sbjct: 378  DMDEVVIVNVPSYITSLEQFLESTPKRVQANYVMWRVAGASVSYLTDELRRRQLSYVTVL 437

Query: 1062 S-RTDRETLCKEKV---MNNFQIAVGALYIRKYFNINSREGAIRLLSDIKRQFPRQISGG 1229
            S +T+RE+  KE V     +  I+VGALYIRKYFN +S++ A+ ++ DI+ QF R +   
Sbjct: 438  SGKTERESRWKECVDTTSMSLSISVGALYIRKYFNEDSKKNALEMVKDIREQFRRTLE-E 496

Query: 1230 PEAM--ALRTHIKEVFSTMKTIVGYPDDLMNDTVLEEYYNELEISKGSFLSSSLNLTRHG 1403
             E M    R         M   + YPD+++ND  L E+Y  LE+S+   + S LNLT  G
Sbjct: 497  VEWMDDTTRRAALAKADAMAAHIAYPDEMLNDEKLSEFYEGLEMSEDKLMESVLNLTLFG 556

Query: 1404 -----EQRKRVYDPEDWANNQEFLLTPNAAYNLVLKSVEISTALLQSPFYGSKNPAYMNY 1568
                 ++ ++  +  DW  +    +  NA Y+ +  S++    +LQ  F+ +  PAYMNY
Sbjct: 557  TDYLFQKLRQPVNKTDWVTHGRPAIV-NAFYSSIENSIQFPAGILQGAFFSALRPAYMNY 615

Query: 1569 GGMGFVVGHELAHALYLDEGVMAHEE----------------ERFKCILKQYSKH 1685
            G +GFV+GHE+ H  + D+G    ++                ++ KCI+ QYS +
Sbjct: 616  GAIGFVIGHEITHG-FDDQGRQFDKDGNLVDWWQEETKQKYLKKAKCIIDQYSNY 669


>ref|XP_003701340.1| PREDICTED: membrane metallo-endopeptidase-like 1 isoform X4
            [Megachile rotundata]
          Length = 765

 Score =  297 bits (761), Expect = 7e-88
 Identities = 177/570 (31%), Positives = 310/570 (54%), Gaps = 49/570 (8%)
 Frame = +3

Query: 132  CNSKECQDLSNYFDGNMNEEIDPCEDFYEFACGNFSKNAVLDKDTLMESTFTLAGQRIKD 311
            C + EC   ++    NM+ E++PC+DFY+FACG F K+  +  D    +TFT  G  +++
Sbjct: 87   CFTPECIHTASRLLKNMDNEVEPCDDFYDFACGGFLKSTNIPDDKTSVNTFTEIGDELQN 146

Query: 312  KIFNDLEHHKNPYKLKTFDKVKIFYENCKNEKKGNTDGVDYFLEQAKEFGGWPLLAGNKW 491
            ++   +E   +P + K F   K  Y+ C N+      G++  ++  ++ GGWP+L G+ W
Sbjct: 147  QLRTSIEEKSSPDEPKPFRLAKNLYKACMNKTVIEQQGLEPLMKILEKLGGWPVLEGDNW 206

Query: 492  NEDNFEWISLLSKMRSRGFKINYPYTITMATLPVISAPSVNKYLELAAAT---------- 641
            NE++F W   + K R  G+ ++Y    ++    V    S  + ++L  A+          
Sbjct: 207  NENDFHWTESVYKFRKMGYSVDYFIDFSIG---VDLKNSTKRIIDLDQASLGLSREYLSK 263

Query: 642  GKVNKIVRAYYSKMVSLAVMLGADEEVAINEMMEVLAFELKLMKLKVIYEGTKS---LVN 812
            G  +KIV+AYYS MV +AV+LGA++  A+ E+ E L FE+KL  + +  E  ++   L N
Sbjct: 264  GFTDKIVQAYYSYMVDIAVILGANKTTAMEELKESLEFEIKLANISLPNEKRRNATLLYN 323

Query: 813  -VKVKHLSMIYPTTDWVKLFNTLSNPYDNYFEKDTDIILTNVKLIVSLNQLLKNTPKRVQ 989
             + V+ LS  Y +  W + FNTL  P     E++  +I++    I +L +LL  TPKRVQ
Sbjct: 324  PMSVRELSTTYSSVPWKEYFNTLLAPSVQVTEEEV-VIVSVPSYIANLQKLLATTPKRVQ 382

Query: 990  ANYMFWKVFFDSITYMSDD-------YVEVIS-RTDRETL---CKEKVMNNFQIAVGALY 1136
            ANY+ W+    S++Y++D+       Y   +S +T+RE     C + V  +  I+VGA+Y
Sbjct: 383  ANYVMWRAAASSVSYLTDEIRKRQLKYSTALSGKTEREPRWKECIDTVSGSLAISVGAMY 442

Query: 1137 IRKYFNINSREGAIRLLSDIKRQFPRQIS--GGPEAMALRTHIKEVFSTMKTIVGYPDDL 1310
            +RKYF  ++++ A+ +++DI+ +F + +      +    ++ +K+  ++M + + YPD+L
Sbjct: 443  VRKYFKEDAKKNALEMVADIREEFTKILKKVDWMDEDTRKSALKKA-ASMSSHIAYPDEL 501

Query: 1311 MNDTVLEEYYNELEISKGSFLSSSLNLTRHGEQ-----RKRVYDPEDWANNQEFLLTPNA 1475
            ++D  LEE+Y +LE++  ++L   LNLT  G +      ++  +  DW  +    +  NA
Sbjct: 502  LDDKKLEEFYEKLELTTDNYLEGILNLTLFGVEYSFGKLRKPVNKSDWVTHGRPAIV-NA 560

Query: 1476 AYNLVLKSVEISTALLQSPFYGSKNPAYMNYGGMGFVVGHELAHALYLDEGVMAHEE--- 1646
             Y+ +  S++    +LQ  F+ +  P YMNYG +GFV+GHE+ H  + D+G    ++   
Sbjct: 561  FYSSIENSIQFPAGILQGAFFSNDRPRYMNYGAIGFVIGHEITHG-FDDQGRQFDKDGNL 619

Query: 1647 -------------ERFKCILKQYSKH-VED 1694
                         ER +CI+ QY  + VED
Sbjct: 620  IDWWAPQTKEKYLERAECIIHQYGNYTVED 649


>ref|XP_017882784.1| PREDICTED: neprilysin isoform X2 [Ceratina calcarata]
          Length = 765

 Score =  297 bits (761), Expect = 7e-88
 Identities = 181/571 (31%), Positives = 311/571 (54%), Gaps = 50/571 (8%)
 Frame = +3

Query: 132  CNSKECQDLSNYFDGNMNEEIDPCEDFYEFACGNFSKNAVLDKDTLMESTFTLAGQRIKD 311
            C + EC   ++    NM+ E++PC+DFY+FACG F K+  +  D    +TFT     ++ 
Sbjct: 87   CYTPECIHTASRLLTNMDLEVEPCDDFYDFACGGFLKSTTIPDDKTSVNTFTGISDDLQK 146

Query: 312  KIFNDLEHHKNPYKLKTFDKVKIFYENCKNEKKGNTDGVDYFLEQAKEFGGWPLLAGNKW 491
            ++   +E   +P + K F  VK  Y+ C N+      G+D  L   ++ GGWP+L G +W
Sbjct: 147  QLRISIEEKSSPDEPKPFRLVKNLYKACMNKTLIEQQGLDPLLNILRKLGGWPVLEGGQW 206

Query: 492  NEDNFEWISLLSKMRSRGFKINYPYTITMATLPVISAPSVNKYLELAAAT---------- 641
            NED F W   + K R  G+ ++Y    ++    V    S  + ++L  A+          
Sbjct: 207  NEDAFNWKESVYKFREMGYSVDYFIDFSIG---VDLKNSTKRIIDLDQASLGLSREYLSK 263

Query: 642  GKVNKIVRAYYSKMVSLAVMLGADEEVAINEMMEVLAFELKLMKLKVIYEGTKS---LVN 812
            G  +KIV+AYY+ MV +AV+LGA++  A++E+ E L FE+ L  + +  E  ++   L N
Sbjct: 264  GFDDKIVQAYYNYMVDIAVILGANKTDAMSELKESLEFEMNLANISLPNEKRRNATLLYN 323

Query: 813  -VKVKHLSMIYPTTDWVKLFNTLSNPYDNYFEKDTDIILTNV-KLIVSLNQLLKNTPKRV 986
             + V+ LS  YP+  W + FNTL  P  N    + ++++ +V   I +L +LL +TPKRV
Sbjct: 324  PMTVQELSNNYPSVPWKEYFNTLLAP--NIQVDENEVVIVSVPSYITNLEKLLDSTPKRV 381

Query: 987  QANYMFWKVFFDSITYMSDD-------YVEVIS-RTDRETL---CKEKVMNNFQIAVGAL 1133
            QANY+ W+    S++Y++DD       Y   +S RT+RE+    C + V  +  I+VGA+
Sbjct: 382  QANYVMWRAAASSVSYLTDDIRKRQLQYSTALSGRTERESRWKECTDTVSGSLAISVGAM 441

Query: 1134 YIRKYFNINSREGAIRLLSDIKRQFPRQIS--GGPEAMALRTHIKEVFSTMKTIVGYPDD 1307
            Y+RKYF  ++++ A+ +++DI+ +F + +      +    ++ +K+  ++M + + YPD+
Sbjct: 442  YVRKYFKEDAKKNAVEMVADIREEFTKILKKVDWMDDETRKSALKKA-ASMSSHIAYPDE 500

Query: 1308 LMNDTVLEEYYNELEISKGSFLSSSLNLTRHG-----EQRKRVYDPEDWANNQEFLLTPN 1472
            L++D  LEE+Y +LE++  ++L   LNLT  G      + ++  +  DW  +    +  N
Sbjct: 501  LLDDKKLEEFYEKLELTTDNYLEGILNLTLFGVEYSFSKLRKPVNKSDWVTHGRPAIV-N 559

Query: 1473 AAYNLVLKSVEISTALLQSPFYGSKNPAYMNYGGMGFVVGHELAHALYLDEGVMAHEE-- 1646
            A Y+ +  S++    +LQ  F+ +  P YMNYG +GFV+GHE+ H  + D+G    ++  
Sbjct: 560  AFYSSIENSIQFPAGILQGAFFSNDRPRYMNYGAIGFVIGHEITHG-FDDQGRQFDKDGN 618

Query: 1647 --------------ERFKCILKQYSKH-VED 1694
                          ER +CI+ QY  + VED
Sbjct: 619  LVDWWAPQTKENYLERAECIIHQYGNYTVED 649


>ref|NP_001036959.1| neutral endopeptidase 24.11 [Bombyx mori]
 dbj|BAB33300.1| neutral endopeptidase 24.11 [Bombyx mori]
          Length = 772

 Score =  297 bits (761), Expect = 8e-88
 Identities = 188/593 (31%), Positives = 315/593 (53%), Gaps = 54/593 (9%)
 Frame = +3

Query: 69   PESNEVRIEKTLPSSDVA-----CTPCNSKECQDLSNYFDGNMNEEIDPCEDFYEFACGN 233
            P+++E+R+  ++P + VA        C++  C   ++    NM+E++DPC++FY+FACG+
Sbjct: 67   PQTSELRLSSSMPPAVVARGSDDVETCSAPGCIHTASRLLLNMDEKVDPCDNFYDFACGS 126

Query: 234  FSKNAVLDKDTLMESTFTLAGQRIKDKIFNDLEHHKNPYKLKTFDKVKIFYENCKNEKKG 413
            F KN  +  D    +TF++   +++++I + L+    P + + F   K  Y+ C N    
Sbjct: 127  FLKNTRIPGDKTSVNTFSIITDQLQEQIRSLLDEPVTPEEPRPFVLAKTLYQACMNRTAI 186

Query: 414  NTDGVDYFLEQAKEFGGWPLLAGNKWNEDNFEWISLLSKMRSRGFKINYPYTITMATLPV 593
               GV   L+  K  GGWP+L G  W+E++F W   + K R  G+ ++Y    +++   V
Sbjct: 187  EARGVQPLLDMLKRLGGWPVLDGQSWDENSFSWEQSVYKFRDAGYSVDYFLDFSIS---V 243

Query: 594  ISAPSVNKYLELAAAT----------GKVNKIVRAYYSKMVSLAVMLGADEEVAINEMME 743
                S  + ++L  A+          G  +K+V+AYY  MV +A++LGAD+  A  E+ E
Sbjct: 244  DVKNSTRRVIDLDQASLGLSREYLNRGFSDKLVQAYYEYMVDIAILLGADKTKATEELKE 303

Query: 744  VLAFELKLMKLKVIYE---GTKSLVN-VKVKHLSMIYPTTDWVKLFNTLSNPYDNYFEKD 911
             L FE+KL  + +  E      SL N + +  L   +P   W++  N L  P+      +
Sbjct: 304  SLQFEMKLANISLPLEKRRNATSLYNPMTIAELQQKFPKVPWLEYINRLLAPHITVDVNE 363

Query: 912  TDIILTNVKLIVSLNQLLKNTPKRVQANYMFWKVFFDSITYMSDD-------YVEVIS-R 1067
              I+ +  K I  L  LL+ TPKRVQANY+ W+V   S++Y++DD       Y+  +S +
Sbjct: 364  LTIV-SVPKYITDLEALLEKTPKRVQANYVMWRVAGASVSYLTDDLRRRQLAYITALSGK 422

Query: 1068 TDRETL---CKEKVMNNFQIAVGALYIRKYFNINSREGAIRLLSDIKRQFPRQIS--GGP 1232
            T+RE+    C +    +  IAVGALYIRKYFN NS+  A+ +++DI++QF + ++     
Sbjct: 423  TERESRWKECADTTSASMSIAVGALYIRKYFNENSKANALEMVNDIRQQFRKTLTKVDWM 482

Query: 1233 EAMALRTHIKEVFSTMKTIVGYPDDLMNDTVLEEYYNELEISKGSFLSSSLNLT------ 1394
            + M  R    E    M + + YP +++++  L E+Y+ LE+S    + S LNLT      
Sbjct: 483  DDMT-RQEALEKADAMASHIAYPSEMLDNNRLTEFYSGLEMSSEHLMESVLNLTLFTTEY 541

Query: 1395 RHGEQRKRVYDPEDWANNQEFLLTPNAAYNLVLKSVEISTALLQSPFYGSKNPAYMNYGG 1574
              G+ R+ V +  DW  +    +  NA Y+ +  S++    +LQ  F+ +K PAYMNYG 
Sbjct: 542  LFGKLREPV-NKTDWVTHGRPAIV-NAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGA 599

Query: 1575 MGFVVGHELAHALYLDEG--------------VMAHEE--ERFKCILKQYSKH 1685
            +GFV+GHE+ H  + D+G               M  E+  ++ KCI+ QYS +
Sbjct: 600  IGFVIGHEITHG-FDDQGRQFDKNGNLVDWWQEMTKEKYLDKAKCIIDQYSNY 651


>ref|XP_012548893.1| neutral endopeptidase 24.11 isoform X1 [Bombyx mori]
          Length = 792

 Score =  298 bits (762), Expect = 8e-88
 Identities = 188/593 (31%), Positives = 315/593 (53%), Gaps = 54/593 (9%)
 Frame = +3

Query: 69   PESNEVRIEKTLPSSDVA-----CTPCNSKECQDLSNYFDGNMNEEIDPCEDFYEFACGN 233
            P+++E+R+  ++P + VA        C++  C   ++    NM+E++DPC++FY+FACG+
Sbjct: 87   PQTSELRLSSSMPPAVVARGSDDVETCSAPGCIHTASRLLLNMDEKVDPCDNFYDFACGS 146

Query: 234  FSKNAVLDKDTLMESTFTLAGQRIKDKIFNDLEHHKNPYKLKTFDKVKIFYENCKNEKKG 413
            F KN  +  D    +TF++   +++++I + L+    P + + F   K  Y+ C N    
Sbjct: 147  FLKNTRIPDDKTSVNTFSIITDQLQEQIRSLLDEPVTPEEPRPFVLAKTLYQACMNRTAI 206

Query: 414  NTDGVDYFLEQAKEFGGWPLLAGNKWNEDNFEWISLLSKMRSRGFKINYPYTITMATLPV 593
               GV   L+  K  GGWP+L G  W+E++F W   + K R  G+ ++Y    +++   V
Sbjct: 207  EARGVQPLLDMLKRLGGWPVLDGQSWDENSFSWEQSVYKFRDAGYSVDYFLDFSIS---V 263

Query: 594  ISAPSVNKYLELAAAT----------GKVNKIVRAYYSKMVSLAVMLGADEEVAINEMME 743
                S  + ++L  A+          G  +K+V+AYY  MV +A++LGAD+  A  E+ E
Sbjct: 264  DVKNSTRRVIDLDQASLGLSREYLNRGFSDKLVQAYYEYMVDIAILLGADKTKATEELKE 323

Query: 744  VLAFELKLMKLKVIYE---GTKSLVN-VKVKHLSMIYPTTDWVKLFNTLSNPYDNYFEKD 911
             L FE+KL  + +  E      SL N + +  L   +P   W++  N L  P+      +
Sbjct: 324  SLQFEMKLANISLPLEKRRNATSLYNPMTIAELQQKFPKVPWLEYINRLLAPHITVDVNE 383

Query: 912  TDIILTNVKLIVSLNQLLKNTPKRVQANYMFWKVFFDSITYMSDD-------YVEVIS-R 1067
              I+ +  K I  L  LL+ TPKRVQANY+ W+V   S++Y++DD       Y+  +S +
Sbjct: 384  LTIV-SVPKYITDLEALLEKTPKRVQANYVMWRVAGASVSYLTDDLRRRQLAYITALSGK 442

Query: 1068 TDRETL---CKEKVMNNFQIAVGALYIRKYFNINSREGAIRLLSDIKRQFPRQIS--GGP 1232
            T+RE+    C +    +  IAVGALYIRKYFN NS+  A+ +++DI++QF + ++     
Sbjct: 443  TERESRWKECADTTSASMSIAVGALYIRKYFNENSKANALEMVNDIRQQFRKTLTKVDWM 502

Query: 1233 EAMALRTHIKEVFSTMKTIVGYPDDLMNDTVLEEYYNELEISKGSFLSSSLNLT------ 1394
            + M  R    E    M + + YP +++++  L E+Y+ LE+S    + S LNLT      
Sbjct: 503  DDMT-RQEALEKADAMASHIAYPSEMLDNNRLTEFYSGLEMSSEHLMESVLNLTLFTTEY 561

Query: 1395 RHGEQRKRVYDPEDWANNQEFLLTPNAAYNLVLKSVEISTALLQSPFYGSKNPAYMNYGG 1574
              G+ R+ V +  DW  +    +  NA Y+ +  S++    +LQ  F+ +K PAYMNYG 
Sbjct: 562  LFGKLREPV-NKTDWVTHGRPAIV-NAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGA 619

Query: 1575 MGFVVGHELAHALYLDEG--------------VMAHEE--ERFKCILKQYSKH 1685
            +GFV+GHE+ H  + D+G               M  E+  ++ KCI+ QYS +
Sbjct: 620  IGFVIGHEITHG-FDDQGRQFDKNGNLVDWWQEMTKEKYLDKAKCIIDQYSNY 671


>ref|XP_012136071.1| PREDICTED: membrane metallo-endopeptidase-like 1 isoform X3
            [Megachile rotundata]
          Length = 776

 Score =  297 bits (761), Expect = 8e-88
 Identities = 177/570 (31%), Positives = 310/570 (54%), Gaps = 49/570 (8%)
 Frame = +3

Query: 132  CNSKECQDLSNYFDGNMNEEIDPCEDFYEFACGNFSKNAVLDKDTLMESTFTLAGQRIKD 311
            C + EC   ++    NM+ E++PC+DFY+FACG F K+  +  D    +TFT  G  +++
Sbjct: 98   CFTPECIHTASRLLKNMDNEVEPCDDFYDFACGGFLKSTNIPDDKTSVNTFTEIGDELQN 157

Query: 312  KIFNDLEHHKNPYKLKTFDKVKIFYENCKNEKKGNTDGVDYFLEQAKEFGGWPLLAGNKW 491
            ++   +E   +P + K F   K  Y+ C N+      G++  ++  ++ GGWP+L G+ W
Sbjct: 158  QLRTSIEEKSSPDEPKPFRLAKNLYKACMNKTVIEQQGLEPLMKILEKLGGWPVLEGDNW 217

Query: 492  NEDNFEWISLLSKMRSRGFKINYPYTITMATLPVISAPSVNKYLELAAAT---------- 641
            NE++F W   + K R  G+ ++Y    ++    V    S  + ++L  A+          
Sbjct: 218  NENDFHWTESVYKFRKMGYSVDYFIDFSIG---VDLKNSTKRIIDLDQASLGLSREYLSK 274

Query: 642  GKVNKIVRAYYSKMVSLAVMLGADEEVAINEMMEVLAFELKLMKLKVIYEGTKS---LVN 812
            G  +KIV+AYYS MV +AV+LGA++  A+ E+ E L FE+KL  + +  E  ++   L N
Sbjct: 275  GFTDKIVQAYYSYMVDIAVILGANKTTAMEELKESLEFEIKLANISLPNEKRRNATLLYN 334

Query: 813  -VKVKHLSMIYPTTDWVKLFNTLSNPYDNYFEKDTDIILTNVKLIVSLNQLLKNTPKRVQ 989
             + V+ LS  Y +  W + FNTL  P     E++  +I++    I +L +LL  TPKRVQ
Sbjct: 335  PMSVRELSTTYSSVPWKEYFNTLLAPSVQVTEEEV-VIVSVPSYIANLQKLLATTPKRVQ 393

Query: 990  ANYMFWKVFFDSITYMSDD-------YVEVIS-RTDRETL---CKEKVMNNFQIAVGALY 1136
            ANY+ W+    S++Y++D+       Y   +S +T+RE     C + V  +  I+VGA+Y
Sbjct: 394  ANYVMWRAAASSVSYLTDEIRKRQLKYSTALSGKTEREPRWKECIDTVSGSLAISVGAMY 453

Query: 1137 IRKYFNINSREGAIRLLSDIKRQFPRQIS--GGPEAMALRTHIKEVFSTMKTIVGYPDDL 1310
            +RKYF  ++++ A+ +++DI+ +F + +      +    ++ +K+  ++M + + YPD+L
Sbjct: 454  VRKYFKEDAKKNALEMVADIREEFTKILKKVDWMDEDTRKSALKKA-ASMSSHIAYPDEL 512

Query: 1311 MNDTVLEEYYNELEISKGSFLSSSLNLTRHGEQ-----RKRVYDPEDWANNQEFLLTPNA 1475
            ++D  LEE+Y +LE++  ++L   LNLT  G +      ++  +  DW  +    +  NA
Sbjct: 513  LDDKKLEEFYEKLELTTDNYLEGILNLTLFGVEYSFGKLRKPVNKSDWVTHGRPAIV-NA 571

Query: 1476 AYNLVLKSVEISTALLQSPFYGSKNPAYMNYGGMGFVVGHELAHALYLDEGVMAHEE--- 1646
             Y+ +  S++    +LQ  F+ +  P YMNYG +GFV+GHE+ H  + D+G    ++   
Sbjct: 572  FYSSIENSIQFPAGILQGAFFSNDRPRYMNYGAIGFVIGHEITHG-FDDQGRQFDKDGNL 630

Query: 1647 -------------ERFKCILKQYSKH-VED 1694
                         ER +CI+ QY  + VED
Sbjct: 631  IDWWAPQTKEKYLERAECIIHQYGNYTVED 660


>gb|KPJ09289.1| Neprilysin-2 [Papilio machaon]
          Length = 822

 Score =  298 bits (763), Expect = 1e-87
 Identities = 195/595 (32%), Positives = 314/595 (52%), Gaps = 54/595 (9%)
 Frame = +3

Query: 63   YSPESNEVRIE--KTLP----SSDVACTPCNSKECQDLSNYFDGNMNEEIDPCEDFYEFA 224
            Y P+++E+RI   +++P     SD     C S  C   ++    NM++ +DPC+DFYEF+
Sbjct: 116  YLPQTSEMRISSPQSMPPAVFGSDYEI--CYSPGCVHTASKLLSNMDQNVDPCDDFYEFS 173

Query: 225  CGNFSKNAVLDKDTLMESTFTLAGQRIKDKIFNDLEHHKNPYKLKTFDKVKIFYENCKNE 404
            CG+F KN  +  D    +TF++   +++++I   LE      +   F   K  Y+ C N+
Sbjct: 174  CGSFEKNTRIPDDKSSVNTFSIITDQLQEQIRALLEEPITEGEPHPFILAKTLYKACMNK 233

Query: 405  KKGNTDGVDYFLEQAKEFGGWPLLAGNKWNEDNFEWISLLSKMRSRGFKINYPYTITMAT 584
                  GV   L+  K FGGWP+L G+ WNE  F W   + + R+ G+ ++Y    +++ 
Sbjct: 234  SVIEARGVKPLLDIMKRFGGWPVLEGDNWNEHAFAWDDSVYRFRTAGYSVDYFLDFSIS- 292

Query: 585  LPVISAPSVNKYLELAAAT----------GKVNKIVRAYYSKMVSLAVMLGADEEVAINE 734
              V    S  + ++L  A+          G  +K+V+AYYS MV ++V+LGAD + A  E
Sbjct: 293  --VDVKNSTKRIIDLDQASLGLSREYLSHGFNDKLVQAYYSYMVDISVLLGADRKRAETE 350

Query: 735  MMEVLAFELKLMKLKVIYE---GTKSLVN-VKVKHLSMIYPTTDWVKLFNTLSNPYDNYF 902
            + E L FE+ L  + +  E      +L N + V  L   +P  DW+K  N L  P+ +  
Sbjct: 351  LRESLDFEITLANISLPLEKRRNATALYNPMTVTQLQKRFPKVDWMKYINRLLAPHVS-I 409

Query: 903  EKDTDIILTNVKLIVSLNQLLKNTPKRVQANYMFWKVFFDSITYMSDD-------YVEVI 1061
            + D  +I+     I SL Q L++TPKRVQANY+ W+V   S++Y++D+       YV V+
Sbjct: 410  DMDEVVIVNVPSYITSLEQFLESTPKRVQANYVMWRVAGASVSYLTDELRRRQLSYVTVL 469

Query: 1062 S-RTDRETLCKEKV---MNNFQIAVGALYIRKYFNINSREGAIRLLSDIKRQFPRQISGG 1229
            S +T+RE+  KE V     +  I+VGALYIRKYFN +S++ A+ ++ DI+ QF R +   
Sbjct: 470  SGKTERESRWKECVDTTSMSLSISVGALYIRKYFNEDSKKNALEMVKDIREQFRRTLE-E 528

Query: 1230 PEAM--ALRTHIKEVFSTMKTIVGYPDDLMNDTVLEEYYNELEISKGSFLSSSLNLTRHG 1403
             E M    R         M   + YPD+++ND  L E+Y  LE+S+   + S LNLT  G
Sbjct: 529  VEWMDDTTRRAALAKADAMAAHIAYPDEMLNDEKLSEFYEGLEMSEDKLMESVLNLTLFG 588

Query: 1404 -----EQRKRVYDPEDWANNQEFLLTPNAAYNLVLKSVEISTALLQSPFYGSKNPAYMNY 1568
                 ++ ++  +  DW  +    +  NA Y+ +  S++    +LQ  F+ +  PAYMNY
Sbjct: 589  TDYLFQKLRQPVNKTDWVTHGRPAIV-NAFYSSIENSIQFPAGILQGAFFSALRPAYMNY 647

Query: 1569 GGMGFVVGHELAHALYLDEGVMAHEE----------------ERFKCILKQYSKH 1685
            G +GFV+GHE+ H  + D+G    ++                ++ KCI+ QYS +
Sbjct: 648  GAIGFVIGHEITHG-FDDQGRQFDKDGNLVDWWQEETKQKYLKKAKCIIDQYSNY 701