BLASTX 2.2.26 [Sep-21-2011]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= Ophiopogon23_contig00004479
         (3980 letters)

Database: All non-redundant GenBank CDS
translations+PDB+SwissProt+PIR+PRF excluding environmental samples
from WGS projects 
           149,584,005 sequences; 54,822,741,787 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

ref|XP_020260991.1| Niemann-Pick C1 protein-like isoform X1 [Asp...  2051   0.0  
ref|XP_020260992.1| Niemann-Pick C1 protein-like isoform X2 [Asp...  2014   0.0  
ref|XP_020260993.1| Niemann-Pick C1 protein-like isoform X3 [Asp...  1885   0.0  
ref|XP_020084535.1| Niemann-Pick C1 protein-like [Ananas comosus]    1817   0.0  
ref|XP_020240540.1| Niemann-Pick C1 protein isoform X1 [Cajanus ...  1679   0.0  
ref|XP_004976504.2| Niemann-Pick C1 protein [Setaria italica]        1677   0.0  
gb|KQK98466.1| hypothetical protein SETIT_009194mg [Setaria ital...  1677   0.0  
gb|KRH14018.1| hypothetical protein GLYMA_14G001500 [Glycine max]    1670   0.0  
ref|XP_006595638.1| PREDICTED: Niemann-Pick C1 protein isoform X...  1670   0.0  
ref|XP_006595637.1| PREDICTED: Niemann-Pick C1 protein isoform X...  1668   0.0  
ref|XP_006575763.1| PREDICTED: Niemann-Pick C1 protein-like isof...  1658   0.0  
gb|PAN39594.1| hypothetical protein PAHAL_G01943 [Panicum hallii]    1657   0.0  
ref|XP_004491642.1| PREDICTED: Niemann-Pick C1 protein [Cicer ar...  1657   0.0  
ref|XP_007142570.1| hypothetical protein PHAVU_008G291900g [Phas...  1656   0.0  
ref|XP_015636550.1| PREDICTED: Niemann-Pick C1 protein [Oryza sa...  1653   0.0  
ref|XP_021318590.1| Niemann-Pick C1 protein [Sorghum bicolor]        1652   0.0  
ref|XP_016191044.1| Niemann-Pick C1 protein isoform X1 [Arachis ...  1651   0.0  
gb|KHN29878.1| Niemann-Pick C1 protein [Glycine soja]                1648   0.0  
ref|XP_020173434.1| Niemann-Pick C1 protein-like [Aegilops tausc...  1645   0.0  
ref|XP_006652645.2| PREDICTED: Niemann-Pick C1 protein-like [Ory...  1645   0.0  

>ref|XP_020260991.1| Niemann-Pick C1 protein-like isoform X1 [Asparagus officinalis]
 gb|ONK71923.1| uncharacterized protein A4U43_C04F13800 [Asparagus officinalis]
          Length = 1289

 Score = 2051 bits (5315), Expect = 0.0
 Identities = 1027/1246 (82%), Positives = 1100/1246 (88%), Gaps = 2/1246 (0%)
 Frame = +1

Query: 247  IQVNLHVFSASAQDSHSHFRILAGARPEKISAEGYCSMYGICEKRSDGKPLNCPSNTPSV 426
            IQVNLHVFSAS QD   HFR+L  + PEKI AEG+CSMYGIC +RSDGKPLNCP NTPSV
Sbjct: 14   IQVNLHVFSASTQDYQPHFRMLTDSEPEKIYAEGFCSMYGICAERSDGKPLNCPFNTPSV 73

Query: 427  KPDKLLSSKVQSLCPTITGNVCCTADQFDTLRGQVQQAIPFLVGCPACLRNFLNVFCELS 606
            KPDKLLSSKVQSLCPTITGNVCCTADQFDTLR QVQQAIP +VGCPACLRNFLN+FCELS
Sbjct: 74   KPDKLLSSKVQSLCPTITGNVCCTADQFDTLRKQVQQAIPLIVGCPACLRNFLNLFCELS 133

Query: 607  CSPNQSLFINVTSVMKGSNTTTVDGIDLYITSTYGEALYNSCKDVKFGTMNTRAMDFIGG 786
            CSPNQSLFINVTS++K +NTT VDGIDLYITSTY E LYNSCKDVKFGTMN+RAM+ IGG
Sbjct: 134  CSPNQSLFINVTSILKVTNTTAVDGIDLYITSTYAEELYNSCKDVKFGTMNSRAMELIGG 193

Query: 787  GAQNYNEWFAFIGKQAGVGEIGSPYAIDFRSNISDSSGMKPMNVTVHSCGDLSLGCSCGD 966
            GAQNY EW AF+GK+AG GE GSPYAIDFRSNI  SS +KP+NVTVH CGD SLGCSCGD
Sbjct: 194  GAQNYTEWLAFMGKRAGDGEPGSPYAIDFRSNIFASSVIKPLNVTVHPCGDPSLGCSCGD 253

Query: 967  CPSSSVCSESATPASHKQGSCHVKMGSLEVNCLEFSLAVVYIVFISVLLLWGLLHRKRVK 1146
            CPSSSVCSESA PASHK GSC +KMGSLEV CLE SLA++YI FI  +LLW LLHR+RVK
Sbjct: 254  CPSSSVCSESAPPASHKNGSCRIKMGSLEVRCLELSLAIMYIAFICAILLWTLLHRRRVK 313

Query: 1147 EGPSSKTNPLVNVKDENE--PVNKQETSIQPVQIPEGPPAVQALQPSIVQRYMSSFFRKY 1320
            + PSS+TNPLVNV+DENE    +KQE S+Q VQIPE PP  QALQPS+VQ YMS+FFRKY
Sbjct: 314  KDPSSRTNPLVNVRDENELQGADKQENSVQHVQIPEDPPVAQALQPSVVQGYMSNFFRKY 373

Query: 1321 GAFVSRKPLLILCLSVAVPLLLCIGLVRFKVETRPEKLWVGPGSKAAEEKKYFDYHLAPF 1500
            G FVSRKP+L+LCLSVAVPLLLCIG VRFKVETRPEKLWVGPGSKAAEEKKYFD HLAPF
Sbjct: 374  GTFVSRKPMLVLCLSVAVPLLLCIGFVRFKVETRPEKLWVGPGSKAAEEKKYFDEHLAPF 433

Query: 1501 YRIEELILATVPGSKDGKSPSIVSDENMKLLFEIQKKIDGLKVNYSGSMISLSDICLKPL 1680
            YRIE+LILAT+P SKDGKSPSIV+D+N+KLLFEIQ KIDGLK NYSGSM+SL+DICLKPL
Sbjct: 434  YRIEQLILATIPDSKDGKSPSIVTDKNIKLLFEIQNKIDGLKANYSGSMVSLTDICLKPL 493

Query: 1681 GDACATQSVLQYFKMDPENYNNYGGVEHADYCFLHYSSAETCLSAFQAPLDPSTALGGFS 1860
            GD CATQSVLQYFKMDPE Y+ YGGV+HA+YCFLHYSSAE+CLSAFQAPLDPSTALGGFS
Sbjct: 494  GDDCATQSVLQYFKMDPEKYSEYGGVDHAEYCFLHYSSAESCLSAFQAPLDPSTALGGFS 553

Query: 1861 GNNFSEASAFVITYPVNNEVERTGNENGKAVAWEKAFVRLVKEEIGPMVKLQNLTLSFSS 2040
            G+N+SEASAFVITYPVNNEV+RTGNENGKAVAWEKAFV+LVKEEI PM K Q+LT SFSS
Sbjct: 554  GSNYSEASAFVITYPVNNEVDRTGNENGKAVAWEKAFVQLVKEEITPMAKSQHLTFSFSS 613

Query: 2041 ESSVQEELKRESSADVITILVSYLVMFAYISFTLGDSPHXXXXXXXXXXXXXXXXXXXXX 2220
            ESSVQEEL RES+ADVITI+VSYLVMF YISFTLGDSP                      
Sbjct: 614  ESSVQEELTRESTADVITIVVSYLVMFVYISFTLGDSPRLSSSFFTSSKVLLGLSGVVVV 673

Query: 2221 XXXXXXXXXXXXAIGVKSTLIIMEVIPFLVLAVGVDNMCILVHAFKRQPLDLPLEGRVSN 2400
                        AIGV+STLIIMEVIPFLVLAVGVDNMCILVHA KRQPL+LPLEGRVSN
Sbjct: 674  ILSVLGSVGFFSAIGVESTLIIMEVIPFLVLAVGVDNMCILVHAIKRQPLELPLEGRVSN 733

Query: 2401 ALVEVGPSITLASLSEVLAFAVGSFIPMPACRVFSMXXXXXXXXXXXXQVTAFVALIVLD 2580
            ALVEVGPSITLASLSEVLAFAVGSFIPMPACRVFSM            QVTAFVALIVLD
Sbjct: 734  ALVEVGPSITLASLSEVLAFAVGSFIPMPACRVFSMFAALAVLLDFLLQVTAFVALIVLD 793

Query: 2581 FLRAEDYRIDCIPCVKVSLSDESNKGDDPRNLGLVARYMKDVHAPMLEIPGVKMIVIAVF 2760
            FLRA+D RIDC PC+K+S S  S+KG+  RNLGLVARYMK+VHAPMLEIPGVK+IVIAVF
Sbjct: 794  FLRAKDNRIDCAPCIKLSSSHGSDKGEK-RNLGLVARYMKEVHAPMLEIPGVKIIVIAVF 852

Query: 2761 VAFSFASIDLCTRLQPGLEQQVVLPRDSYLQDYFGDLAKYLRVGPPLYFVVKDFNYSLES 2940
            +AFSF SIDL TRLQPGLEQQ+VLPRDSYLQDYF D+AKYLRVGPPLYFVVKDFNYS ES
Sbjct: 853  IAFSFVSIDLSTRLQPGLEQQIVLPRDSYLQDYFEDIAKYLRVGPPLYFVVKDFNYSSES 912

Query: 2941 EQTNQLCSISQCDSNSLLNEITRASLTAESSYIAKPAASWLDDFLIWLSPEAFSCCRKFV 3120
            EQTNQ+CSISQCDSNSLLNEIT ASLT+ESSYIAKPAASWLDDFL+WLSPEAFSCCRKFV
Sbjct: 913  EQTNQICSISQCDSNSLLNEITHASLTSESSYIAKPAASWLDDFLVWLSPEAFSCCRKFV 972

Query: 3121 NGSYXXXXXXXXXXXXGDSSCGMGGICKDCTTCFRHSDLQDGRPSTSQFKEKLPWFLKAL 3300
            NGSY            GDSSCG+ GICKDCTTCFRHSDL DGRPST+QFKEKLPWFLKAL
Sbjct: 973  NGSYCPPDDQPPCCQPGDSSCGIAGICKDCTTCFRHSDLHDGRPSTAQFKEKLPWFLKAL 1032

Query: 3301 PSSNCAKGGNGAYTSSVDLTGYDSGIIQASSFRTYHTPLNKQSDYVNGMRAAREFSSEVS 3480
            PSSNCAKGGNGAYTSSVDLTGY+SG IQASSFRTYHTPLNKQSDYVNGMRAAREFSS+VS
Sbjct: 1033 PSSNCAKGGNGAYTSSVDLTGYESGTIQASSFRTYHTPLNKQSDYVNGMRAAREFSSKVS 1092

Query: 3481 KSLKMQIFPYSVFYIFFEQYLDIWKTALVNILIGLGAVFIVCSVITCSFWTSTIILVVLA 3660
             SLKM+IFPYSVFYIFFEQYLDIWKTAL+NI IGLGAVF+VC  ITCS WTS IILVVLA
Sbjct: 1093 NSLKMEIFPYSVFYIFFEQYLDIWKTALINISIGLGAVFLVCMGITCSLWTSLIILVVLA 1152

Query: 3661 MIVIDMMGVMAILKIQLNAISVVNLVMSIGIAVEFCVHITHSFSVSCGDRGTRARAALCT 3840
            MIVIDMMGVMAILKIQLNA+SVVNLVM+IGIAVEFCVHITHSFS S GDR TRA+AAL T
Sbjct: 1153 MIVIDMMGVMAILKIQLNAVSVVNLVMAIGIAVEFCVHITHSFSASSGDRRTRAKAALST 1212

Query: 3841 MGASIFSGITLTKLVGVIVLRFARSEIFVVYYFQMYLALVLLGFLH 3978
            MGASIFSGITLTKLVGVIVL FA+SEIFVVYYFQMYLALVLLGFLH
Sbjct: 1213 MGASIFSGITLTKLVGVIVLHFAKSEIFVVYYFQMYLALVLLGFLH 1258


>ref|XP_020260992.1| Niemann-Pick C1 protein-like isoform X2 [Asparagus officinalis]
          Length = 1252

 Score = 2014 bits (5218), Expect = 0.0
 Identities = 1008/1218 (82%), Positives = 1079/1218 (88%), Gaps = 2/1218 (0%)
 Frame = +1

Query: 331  KISAEGYCSMYGICEKRSDGKPLNCPSNTPSVKPDKLLSSKVQSLCPTITGNVCCTADQF 510
            KI AEG+CSMYGIC +RSDGKPLNCP NTPSVKPDKLLSSKVQSLCPTITGNVCCTADQF
Sbjct: 5    KIYAEGFCSMYGICAERSDGKPLNCPFNTPSVKPDKLLSSKVQSLCPTITGNVCCTADQF 64

Query: 511  DTLRGQVQQAIPFLVGCPACLRNFLNVFCELSCSPNQSLFINVTSVMKGSNTTTVDGIDL 690
            DTLR QVQQAIP +VGCPACLRNFLN+FCELSCSPNQSLFINVTS++K +NTT VDGIDL
Sbjct: 65   DTLRKQVQQAIPLIVGCPACLRNFLNLFCELSCSPNQSLFINVTSILKVTNTTAVDGIDL 124

Query: 691  YITSTYGEALYNSCKDVKFGTMNTRAMDFIGGGAQNYNEWFAFIGKQAGVGEIGSPYAID 870
            YITSTY E LYNSCKDVKFGTMN+RAM+ IGGGAQNY EW AF+GK+AG GE GSPYAID
Sbjct: 125  YITSTYAEELYNSCKDVKFGTMNSRAMELIGGGAQNYTEWLAFMGKRAGDGEPGSPYAID 184

Query: 871  FRSNISDSSGMKPMNVTVHSCGDLSLGCSCGDCPSSSVCSESATPASHKQGSCHVKMGSL 1050
            FRSNI  SS +KP+NVTVH CGD SLGCSCGDCPSSSVCSESA PASHK GSC +KMGSL
Sbjct: 185  FRSNIFASSVIKPLNVTVHPCGDPSLGCSCGDCPSSSVCSESAPPASHKNGSCRIKMGSL 244

Query: 1051 EVNCLEFSLAVVYIVFISVLLLWGLLHRKRVKEGPSSKTNPLVNVKDENE--PVNKQETS 1224
            EV CLE SLA++YI FI  +LLW LLHR+RVK+ PSS+TNPLVNV+DENE    +KQE S
Sbjct: 245  EVRCLELSLAIMYIAFICAILLWTLLHRRRVKKDPSSRTNPLVNVRDENELQGADKQENS 304

Query: 1225 IQPVQIPEGPPAVQALQPSIVQRYMSSFFRKYGAFVSRKPLLILCLSVAVPLLLCIGLVR 1404
            +Q VQIPE PP  QALQPS+VQ YMS+FFRKYG FVSRKP+L+LCLSVAVPLLLCIG VR
Sbjct: 305  VQHVQIPEDPPVAQALQPSVVQGYMSNFFRKYGTFVSRKPMLVLCLSVAVPLLLCIGFVR 364

Query: 1405 FKVETRPEKLWVGPGSKAAEEKKYFDYHLAPFYRIEELILATVPGSKDGKSPSIVSDENM 1584
            FKVETRPEKLWVGPGSKAAEEKKYFD HLAPFYRIE+LILAT+P SKDGKSPSIV+D+N+
Sbjct: 365  FKVETRPEKLWVGPGSKAAEEKKYFDEHLAPFYRIEQLILATIPDSKDGKSPSIVTDKNI 424

Query: 1585 KLLFEIQKKIDGLKVNYSGSMISLSDICLKPLGDACATQSVLQYFKMDPENYNNYGGVEH 1764
            KLLFEIQ KIDGLK NYSGSM+SL+DICLKPLGD CATQSVLQYFKMDPE Y+ YGGV+H
Sbjct: 425  KLLFEIQNKIDGLKANYSGSMVSLTDICLKPLGDDCATQSVLQYFKMDPEKYSEYGGVDH 484

Query: 1765 ADYCFLHYSSAETCLSAFQAPLDPSTALGGFSGNNFSEASAFVITYPVNNEVERTGNENG 1944
            A+YCFLHYSSAE+CLSAFQAPLDPSTALGGFSG+N+SEASAFVITYPVNNEV+RTGNENG
Sbjct: 485  AEYCFLHYSSAESCLSAFQAPLDPSTALGGFSGSNYSEASAFVITYPVNNEVDRTGNENG 544

Query: 1945 KAVAWEKAFVRLVKEEIGPMVKLQNLTLSFSSESSVQEELKRESSADVITILVSYLVMFA 2124
            KAVAWEKAFV+LVKEEI PM K Q+LT SFSSESSVQEEL RES+ADVITI+VSYLVMF 
Sbjct: 545  KAVAWEKAFVQLVKEEITPMAKSQHLTFSFSSESSVQEELTRESTADVITIVVSYLVMFV 604

Query: 2125 YISFTLGDSPHXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXAIGVKSTLIIMEVIPF 2304
            YISFTLGDSP                                  AIGV+STLIIMEVIPF
Sbjct: 605  YISFTLGDSPRLSSSFFTSSKVLLGLSGVVVVILSVLGSVGFFSAIGVESTLIIMEVIPF 664

Query: 2305 LVLAVGVDNMCILVHAFKRQPLDLPLEGRVSNALVEVGPSITLASLSEVLAFAVGSFIPM 2484
            LVLAVGVDNMCILVHA KRQPL+LPLEGRVSNALVEVGPSITLASLSEVLAFAVGSFIPM
Sbjct: 665  LVLAVGVDNMCILVHAIKRQPLELPLEGRVSNALVEVGPSITLASLSEVLAFAVGSFIPM 724

Query: 2485 PACRVFSMXXXXXXXXXXXXQVTAFVALIVLDFLRAEDYRIDCIPCVKVSLSDESNKGDD 2664
            PACRVFSM            QVTAFVALIVLDFLRA+D RIDC PC+K+S S  S+KG+ 
Sbjct: 725  PACRVFSMFAALAVLLDFLLQVTAFVALIVLDFLRAKDNRIDCAPCIKLSSSHGSDKGEK 784

Query: 2665 PRNLGLVARYMKDVHAPMLEIPGVKMIVIAVFVAFSFASIDLCTRLQPGLEQQVVLPRDS 2844
             RNLGLVARYMK+VHAPMLEIPGVK+IVIAVF+AFSF SIDL TRLQPGLEQQ+VLPRDS
Sbjct: 785  -RNLGLVARYMKEVHAPMLEIPGVKIIVIAVFIAFSFVSIDLSTRLQPGLEQQIVLPRDS 843

Query: 2845 YLQDYFGDLAKYLRVGPPLYFVVKDFNYSLESEQTNQLCSISQCDSNSLLNEITRASLTA 3024
            YLQDYF D+AKYLRVGPPLYFVVKDFNYS ESEQTNQ+CSISQCDSNSLLNEIT ASLT+
Sbjct: 844  YLQDYFEDIAKYLRVGPPLYFVVKDFNYSSESEQTNQICSISQCDSNSLLNEITHASLTS 903

Query: 3025 ESSYIAKPAASWLDDFLIWLSPEAFSCCRKFVNGSYXXXXXXXXXXXXGDSSCGMGGICK 3204
            ESSYIAKPAASWLDDFL+WLSPEAFSCCRKFVNGSY            GDSSCG+ GICK
Sbjct: 904  ESSYIAKPAASWLDDFLVWLSPEAFSCCRKFVNGSYCPPDDQPPCCQPGDSSCGIAGICK 963

Query: 3205 DCTTCFRHSDLQDGRPSTSQFKEKLPWFLKALPSSNCAKGGNGAYTSSVDLTGYDSGIIQ 3384
            DCTTCFRHSDL DGRPST+QFKEKLPWFLKALPSSNCAKGGNGAYTSSVDLTGY+SG IQ
Sbjct: 964  DCTTCFRHSDLHDGRPSTAQFKEKLPWFLKALPSSNCAKGGNGAYTSSVDLTGYESGTIQ 1023

Query: 3385 ASSFRTYHTPLNKQSDYVNGMRAAREFSSEVSKSLKMQIFPYSVFYIFFEQYLDIWKTAL 3564
            ASSFRTYHTPLNKQSDYVNGMRAAREFSS+VS SLKM+IFPYSVFYIFFEQYLDIWKTAL
Sbjct: 1024 ASSFRTYHTPLNKQSDYVNGMRAAREFSSKVSNSLKMEIFPYSVFYIFFEQYLDIWKTAL 1083

Query: 3565 VNILIGLGAVFIVCSVITCSFWTSTIILVVLAMIVIDMMGVMAILKIQLNAISVVNLVMS 3744
            +NI IGLGAVF+VC  ITCS WTS IILVVLAMIVIDMMGVMAILKIQLNA+SVVNLVM+
Sbjct: 1084 INISIGLGAVFLVCMGITCSLWTSLIILVVLAMIVIDMMGVMAILKIQLNAVSVVNLVMA 1143

Query: 3745 IGIAVEFCVHITHSFSVSCGDRGTRARAALCTMGASIFSGITLTKLVGVIVLRFARSEIF 3924
            IGIAVEFCVHITHSFS S GDR TRA+AAL TMGASIFSGITLTKLVGVIVL FA+SEIF
Sbjct: 1144 IGIAVEFCVHITHSFSASSGDRRTRAKAALSTMGASIFSGITLTKLVGVIVLHFAKSEIF 1203

Query: 3925 VVYYFQMYLALVLLGFLH 3978
            VVYYFQMYLALVLLGFLH
Sbjct: 1204 VVYYFQMYLALVLLGFLH 1221


>ref|XP_020260993.1| Niemann-Pick C1 protein-like isoform X3 [Asparagus officinalis]
          Length = 1181

 Score = 1885 bits (4883), Expect = 0.0
 Identities = 946/1150 (82%), Positives = 1015/1150 (88%), Gaps = 2/1150 (0%)
 Frame = +1

Query: 535  QAIPFLVGCPACLRNFLNVFCELSCSPNQSLFINVTSVMKGSNTTTVDGIDLYITSTYGE 714
            QAIP +VGCPACLRNFLN+FCELSCSPNQSLFINVTS++K +NTT VDGIDLYITSTY E
Sbjct: 2    QAIPLIVGCPACLRNFLNLFCELSCSPNQSLFINVTSILKVTNTTAVDGIDLYITSTYAE 61

Query: 715  ALYNSCKDVKFGTMNTRAMDFIGGGAQNYNEWFAFIGKQAGVGEIGSPYAIDFRSNISDS 894
             LYNSCKDVKFGTMN+RAM+ IGGGAQNY EW AF+GK+AG GE GSPYAIDFRSNI  S
Sbjct: 62   ELYNSCKDVKFGTMNSRAMELIGGGAQNYTEWLAFMGKRAGDGEPGSPYAIDFRSNIFAS 121

Query: 895  SGMKPMNVTVHSCGDLSLGCSCGDCPSSSVCSESATPASHKQGSCHVKMGSLEVNCLEFS 1074
            S +KP+NVTVH CGD SLGCSCGDCPSSSVCSESA PASHK GSC +KMGSLEV CLE S
Sbjct: 122  SVIKPLNVTVHPCGDPSLGCSCGDCPSSSVCSESAPPASHKNGSCRIKMGSLEVRCLELS 181

Query: 1075 LAVVYIVFISVLLLWGLLHRKRVKEGPSSKTNPLVNVKDENE--PVNKQETSIQPVQIPE 1248
            LA++YI FI  +LLW LLHR+RVK+ PSS+TNPLVNV+DENE    +KQE S+Q VQIPE
Sbjct: 182  LAIMYIAFICAILLWTLLHRRRVKKDPSSRTNPLVNVRDENELQGADKQENSVQHVQIPE 241

Query: 1249 GPPAVQALQPSIVQRYMSSFFRKYGAFVSRKPLLILCLSVAVPLLLCIGLVRFKVETRPE 1428
             PP  QALQPS+VQ YMS+FFRKYG FVSRKP+L+LCLSVAVPLLLCIG VRFKVETRPE
Sbjct: 242  DPPVAQALQPSVVQGYMSNFFRKYGTFVSRKPMLVLCLSVAVPLLLCIGFVRFKVETRPE 301

Query: 1429 KLWVGPGSKAAEEKKYFDYHLAPFYRIEELILATVPGSKDGKSPSIVSDENMKLLFEIQK 1608
            KLWVGPGSKAAEEKKYFD HLAPFYRIE+LILAT+P SKDGKSPSIV+D+N+KLLFEIQ 
Sbjct: 302  KLWVGPGSKAAEEKKYFDEHLAPFYRIEQLILATIPDSKDGKSPSIVTDKNIKLLFEIQN 361

Query: 1609 KIDGLKVNYSGSMISLSDICLKPLGDACATQSVLQYFKMDPENYNNYGGVEHADYCFLHY 1788
            KIDGLK NYSGSM+SL+DICLKPLGD CATQSVLQYFKMDPE Y+ YGGV+HA+YCFLHY
Sbjct: 362  KIDGLKANYSGSMVSLTDICLKPLGDDCATQSVLQYFKMDPEKYSEYGGVDHAEYCFLHY 421

Query: 1789 SSAETCLSAFQAPLDPSTALGGFSGNNFSEASAFVITYPVNNEVERTGNENGKAVAWEKA 1968
            SSAE+CLSAFQAPLDPSTALGGFSG+N+SEASAFVITYPVNNEV+RTGNENGKAVAWEKA
Sbjct: 422  SSAESCLSAFQAPLDPSTALGGFSGSNYSEASAFVITYPVNNEVDRTGNENGKAVAWEKA 481

Query: 1969 FVRLVKEEIGPMVKLQNLTLSFSSESSVQEELKRESSADVITILVSYLVMFAYISFTLGD 2148
            FV+LVKEEI PM K Q+LT SFSSESSVQEEL RES+ADVITI+VSYLVMF YISFTLGD
Sbjct: 482  FVQLVKEEITPMAKSQHLTFSFSSESSVQEELTRESTADVITIVVSYLVMFVYISFTLGD 541

Query: 2149 SPHXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXAIGVKSTLIIMEVIPFLVLAVGVD 2328
            SP                                  AIGV+STLIIMEVIPFLVLAVGVD
Sbjct: 542  SPRLSSSFFTSSKVLLGLSGVVVVILSVLGSVGFFSAIGVESTLIIMEVIPFLVLAVGVD 601

Query: 2329 NMCILVHAFKRQPLDLPLEGRVSNALVEVGPSITLASLSEVLAFAVGSFIPMPACRVFSM 2508
            NMCILVHA KRQPL+LPLEGRVSNALVEVGPSITLASLSEVLAFAVGSFIPMPACRVFSM
Sbjct: 602  NMCILVHAIKRQPLELPLEGRVSNALVEVGPSITLASLSEVLAFAVGSFIPMPACRVFSM 661

Query: 2509 XXXXXXXXXXXXQVTAFVALIVLDFLRAEDYRIDCIPCVKVSLSDESNKGDDPRNLGLVA 2688
                        QVTAFVALIVLDFLRA+D RIDC PC+K+S S  S+KG+  RNLGLVA
Sbjct: 662  FAALAVLLDFLLQVTAFVALIVLDFLRAKDNRIDCAPCIKLSSSHGSDKGEK-RNLGLVA 720

Query: 2689 RYMKDVHAPMLEIPGVKMIVIAVFVAFSFASIDLCTRLQPGLEQQVVLPRDSYLQDYFGD 2868
            RYMK+VHAPMLEIPGVK+IVIAVF+AFSF SIDL TRLQPGLEQQ+VLPRDSYLQDYF D
Sbjct: 721  RYMKEVHAPMLEIPGVKIIVIAVFIAFSFVSIDLSTRLQPGLEQQIVLPRDSYLQDYFED 780

Query: 2869 LAKYLRVGPPLYFVVKDFNYSLESEQTNQLCSISQCDSNSLLNEITRASLTAESSYIAKP 3048
            +AKYLRVGPPLYFVVKDFNYS ESEQTNQ+CSISQCDSNSLLNEIT ASLT+ESSYIAKP
Sbjct: 781  IAKYLRVGPPLYFVVKDFNYSSESEQTNQICSISQCDSNSLLNEITHASLTSESSYIAKP 840

Query: 3049 AASWLDDFLIWLSPEAFSCCRKFVNGSYXXXXXXXXXXXXGDSSCGMGGICKDCTTCFRH 3228
            AASWLDDFL+WLSPEAFSCCRKFVNGSY            GDSSCG+ GICKDCTTCFRH
Sbjct: 841  AASWLDDFLVWLSPEAFSCCRKFVNGSYCPPDDQPPCCQPGDSSCGIAGICKDCTTCFRH 900

Query: 3229 SDLQDGRPSTSQFKEKLPWFLKALPSSNCAKGGNGAYTSSVDLTGYDSGIIQASSFRTYH 3408
            SDL DGRPST+QFKEKLPWFLKALPSSNCAKGGNGAYTSSVDLTGY+SG IQASSFRTYH
Sbjct: 901  SDLHDGRPSTAQFKEKLPWFLKALPSSNCAKGGNGAYTSSVDLTGYESGTIQASSFRTYH 960

Query: 3409 TPLNKQSDYVNGMRAAREFSSEVSKSLKMQIFPYSVFYIFFEQYLDIWKTALVNILIGLG 3588
            TPLNKQSDYVNGMRAAREFSS+VS SLKM+IFPYSVFYIFFEQYLDIWKTAL+NI IGLG
Sbjct: 961  TPLNKQSDYVNGMRAAREFSSKVSNSLKMEIFPYSVFYIFFEQYLDIWKTALINISIGLG 1020

Query: 3589 AVFIVCSVITCSFWTSTIILVVLAMIVIDMMGVMAILKIQLNAISVVNLVMSIGIAVEFC 3768
            AVF+VC  ITCS WTS IILVVLAMIVIDMMGVMAILKIQLNA+SVVNLVM+IGIAVEFC
Sbjct: 1021 AVFLVCMGITCSLWTSLIILVVLAMIVIDMMGVMAILKIQLNAVSVVNLVMAIGIAVEFC 1080

Query: 3769 VHITHSFSVSCGDRGTRARAALCTMGASIFSGITLTKLVGVIVLRFARSEIFVVYYFQMY 3948
            VHITHSFS S GDR TRA+AAL TMGASIFSGITLTKLVGVIVL FA+SEIFVVYYFQMY
Sbjct: 1081 VHITHSFSASSGDRRTRAKAALSTMGASIFSGITLTKLVGVIVLHFAKSEIFVVYYFQMY 1140

Query: 3949 LALVLLGFLH 3978
            LALVLLGFLH
Sbjct: 1141 LALVLLGFLH 1150


>ref|XP_020084535.1| Niemann-Pick C1 protein-like [Ananas comosus]
          Length = 1300

 Score = 1817 bits (4706), Expect = 0.0
 Identities = 899/1247 (72%), Positives = 1036/1247 (83%), Gaps = 3/1247 (0%)
 Frame = +1

Query: 247  IQVNLHVFSASAQDSHSHFRILAGARPEKISAEGYCSMYGICEKRSDGKPLNCPSNTPSV 426
            +Q  +  F A AQ S+            KI AEGYCSMYGIC +RSDGK LNCP+ T + 
Sbjct: 27   LQAIILFFPACAQQSNG--------TSGKIYAEGYCSMYGICGQRSDGKVLNCPNETRAA 78

Query: 427  KPDKLLSSKVQSLCPTITGNVCCTADQFDTLRGQVQQAIPFLVGCPACLRNFLNVFCELS 606
            KPD L S+K+QSLCPTI+GNVCCTADQFDTL   VQQAIPFLVGCPACLRNFLN+FCELS
Sbjct: 79   KPDDLFSAKIQSLCPTISGNVCCTADQFDTLHENVQQAIPFLVGCPACLRNFLNIFCELS 138

Query: 607  CSPNQSLFINVTSVMKGSNTTTVDGIDLYITSTYGEALYNSCKDVKFGTMNTRAMDFIGG 786
            CSPNQSLFINVTS+ + +NT TVDGID ++TS YGE LYNSCKDVKFGTMNTR+MDFIGG
Sbjct: 139  CSPNQSLFINVTSIAEVNNTMTVDGIDFFVTSEYGEELYNSCKDVKFGTMNTRSMDFIGG 198

Query: 787  GAQNYNEWFAFIGKQAGVGEIGSPYAIDFRSNISDSSGMKPMNVTVHSCGDLSLGCSCGD 966
             AQNY EWFAF+G+QA + E GSPYA+ FRS+ISDSSGMKP+N+TV+SCGD SLGCSCGD
Sbjct: 199  AAQNYTEWFAFLGRQANLNEPGSPYAVSFRSDISDSSGMKPLNITVYSCGDHSLGCSCGD 258

Query: 967  CPSSSVCSESATPASHKQGSCHVKMGSLEVNCLEFSLAVVYIVFISVLLLWGLLHRKRVK 1146
            CPSSSVC  +A  AS  + SC  KMGSL+V CLEFSLA+VY V ++  L W  LHRKR +
Sbjct: 259  CPSSSVCMNNAPSASRGKRSCSFKMGSLKVKCLEFSLAIVYFVLLAAFLTWVSLHRKRER 318

Query: 1147 EGPSSKTNPLVNVKDENE--PVNKQETSIQPVQIPEGPPAV-QALQPSIVQRYMSSFFRK 1317
             G  S+T PL NV+D+N+   V+K+E S +P+QI E  P V + L+PS+VQ YM+SFFRK
Sbjct: 319  VGLFSRTEPLQNVQDQNQLHSVSKEELSGRPLQITEEVPLVAETLRPSVVQSYMTSFFRK 378

Query: 1318 YGAFVSRKPLLILCLSVAVPLLLCIGLVRFKVETRPEKLWVGPGSKAAEEKKYFDYHLAP 1497
            YG FV+R P+L+LCLS+AVPLLLCIGL+RFKVETRPEKLWVGPGSKAAEEK+YFD HLAP
Sbjct: 379  YGTFVARNPILVLCLSLAVPLLLCIGLIRFKVETRPEKLWVGPGSKAAEEKQYFDSHLAP 438

Query: 1498 FYRIEELILATVPGSKDGKSPSIVSDENMKLLFEIQKKIDGLKVNYSGSMISLSDICLKP 1677
            FYRIE+LI+AT+P S+   SP+IV+  N++LLFE+QKK+DGL+ NYSG+M+SLSDIC KP
Sbjct: 439  FYRIEQLIVATIPASRTSSSPTIVTGNNIQLLFEVQKKVDGLRANYSGNMVSLSDICFKP 498

Query: 1678 LGDACATQSVLQYFKMDPENYNNYGGVEHADYCFLHYSSAETCLSAFQAPLDPSTALGGF 1857
            LG  CATQSVLQYF+MDP+ YN+ G ++HA YCF H+SS E+CLSAFQAPLDPSTALGGF
Sbjct: 499  LGADCATQSVLQYFQMDPQKYNDLG-IDHAKYCFQHFSSDESCLSAFQAPLDPSTALGGF 557

Query: 1858 SGNNFSEASAFVITYPVNNEVERTGNENGKAVAWEKAFVRLVKEEIGPMVKLQNLTLSFS 2037
            SGNN+SEASAFVITYPVNN+V++TG ENG+AVAWE+AF+ L+KEEI PM+++QNLTL+FS
Sbjct: 558  SGNNYSEASAFVITYPVNNKVDKTGEENGQAVAWEEAFIHLMKEEIMPMIQMQNLTLAFS 617

Query: 2038 SESSVQEELKRESSADVITILVSYLVMFAYISFTLGDSPHXXXXXXXXXXXXXXXXXXXX 2217
            SESS+QEELKRES+AD ITIL+SYLVMFAYISF LGDS                      
Sbjct: 618  SESSIQEELKRESTADAITILISYLVMFAYISFALGDSFRCSSSFIISSKVLLGLSGVVL 677

Query: 2218 XXXXXXXXXXXXXAIGVKSTLIIMEVIPFLVLAVGVDNMCILVHAFKRQPLDLPLEGRVS 2397
                         AIGVKSTLIIMEVIPFLVLAVGVDNMCILVHA KRQPL L LEGR+S
Sbjct: 678  VLLSVLGSIGFFTAIGVKSTLIIMEVIPFLVLAVGVDNMCILVHAVKRQPLALSLEGRIS 737

Query: 2398 NALVEVGPSITLASLSEVLAFAVGSFIPMPACRVFSMXXXXXXXXXXXXQVTAFVALIVL 2577
            NALVEVGPSITLASLSE LAFAV +F PMPACRVFSM            QVTAFVALIV 
Sbjct: 738  NALVEVGPSITLASLSEFLAFAVSTFTPMPACRVFSMFAALAVLLDFVLQVTAFVALIVF 797

Query: 2578 DFLRAEDYRIDCIPCVKVSLSDESNKGDDPRNLGLVARYMKDVHAPMLEIPGVKMIVIAV 2757
            DF+RAE  R+DC+PC+K+S S++ +KGD    LG +ARYMK+VHAP+L + GVK+IVIAV
Sbjct: 798  DFIRAEAGRVDCVPCIKISPSNDPDKGDGQHKLGFLARYMKEVHAPILGLRGVKVIVIAV 857

Query: 2758 FVAFSFASIDLCTRLQPGLEQQVVLPRDSYLQDYFGDLAKYLRVGPPLYFVVKDFNYSLE 2937
            FV F+F SI L TRLQPGLEQ++VLPR+SYLQDYF DLAKYLR+GPPLYFVVKDFNYSLE
Sbjct: 858  FVGFAFTSIVLSTRLQPGLEQKIVLPRNSYLQDYFDDLAKYLRIGPPLYFVVKDFNYSLE 917

Query: 2938 SEQTNQLCSISQCDSNSLLNEITRASLTAESSYIAKPAASWLDDFLIWLSPEAFSCCRKF 3117
            S QTNQ+CSISQC+SNSLLNEI +ASL  ESSYIAKPAASWLDDFLIWLSPEAFSCCR+F
Sbjct: 918  SSQTNQICSISQCNSNSLLNEIAKASLVPESSYIAKPAASWLDDFLIWLSPEAFSCCREF 977

Query: 3118 VNGSYXXXXXXXXXXXXGDSSCGMGGICKDCTTCFRHSDLQDGRPSTSQFKEKLPWFLKA 3297
            VNGSY               SCG+ G CKDCTTCFRHSDL DGRPS +QFKEKLPWFL A
Sbjct: 978  VNGSYCPPDDQPPCCQPSQGSCGVTGKCKDCTTCFRHSDLHDGRPSIAQFKEKLPWFLNA 1037

Query: 3298 LPSSNCAKGGNGAYTSSVDLTGYDSGIIQASSFRTYHTPLNKQSDYVNGMRAAREFSSEV 3477
            LPSS+CAKGG GAYT++V+LTGY+ GIIQAS+FRTYHTPLNKQ+DYVN M+AAR+FSS++
Sbjct: 1038 LPSSDCAKGGKGAYTTNVNLTGYERGIIQASAFRTYHTPLNKQTDYVNSMKAARDFSSKI 1097

Query: 3478 SKSLKMQIFPYSVFYIFFEQYLDIWKTALVNILIGLGAVFIVCSVITCSFWTSTIILVVL 3657
            S SL+MQIFPYSVFYIFFEQYLDIWKT+L+NI IGLGAVF+VC V+T S W S IIL+V+
Sbjct: 1098 SDSLQMQIFPYSVFYIFFEQYLDIWKTSLINISIGLGAVFMVCLVVTGSLWASAIILLVI 1157

Query: 3658 AMIVIDMMGVMAILKIQLNAISVVNLVMSIGIAVEFCVHITHSFSVSCGDRGTRARAALC 3837
            AMI++DMMGVM IL IQLNAISVVNLVMSIGIAVEFCVHITH+FS+S GDR TRA+ ALC
Sbjct: 1158 AMIILDMMGVMGILDIQLNAISVVNLVMSIGIAVEFCVHITHAFSISRGDRNTRAKEALC 1217

Query: 3838 TMGASIFSGITLTKLVGVIVLRFARSEIFVVYYFQMYLALVLLGFLH 3978
            TMGAS+FSGITLTKLVGVIVLRFARSE+FV+YYFQMYLALVL+GFLH
Sbjct: 1218 TMGASVFSGITLTKLVGVIVLRFARSEVFVIYYFQMYLALVLIGFLH 1264


>ref|XP_020240540.1| Niemann-Pick C1 protein isoform X1 [Cajanus cajan]
          Length = 1289

 Score = 1679 bits (4349), Expect = 0.0
 Identities = 819/1220 (67%), Positives = 984/1220 (80%), Gaps = 7/1220 (0%)
 Frame = +1

Query: 340  AEGYCSMYGICEKRSDGKPLNCPSNTPSVKPDKLLSSKVQSLCPTITGNVCCTADQFDTL 519
            +E YC+MY IC +RSDGK LNCP  +PSVKPD LLS+K+QSLCPTITGNVCCTADQFDTL
Sbjct: 35   SEEYCAMYDICGQRSDGKALNCPYGSPSVKPDDLLSAKIQSLCPTITGNVCCTADQFDTL 94

Query: 520  RGQVQQAIPFLVGCPACLRNFLNVFCELSCSPNQSLFINVTSVMKGSNTTTVDGIDLYIT 699
            R QVQQA+P LVGCPACLRNFLN+FCELSCSPNQSLFINVTS+ + +   TVDGI+ YIT
Sbjct: 95   RVQVQQAVPILVGCPACLRNFLNLFCELSCSPNQSLFINVTSISEVNGNMTVDGIEFYIT 154

Query: 700  STYGEALYNSCKDVKFGTMNTRAMDFIGGGAQNYNEWFAFIGKQAGVGEIGSPYAIDFRS 879
             T+GE LY SCKDVKFGTMNTRA+DF+G GA N+ EWFAF+G++   G  GSPY+I F++
Sbjct: 155  ETFGEGLYESCKDVKFGTMNTRAIDFVGAGASNFKEWFAFLGQKVPPGFPGSPYSIQFKT 214

Query: 880  NISDSSGMKPMNVTVHSCGDLSLGCSCGDCPSSSVCSESATPASHKQGSCHVKMGSLEVN 1059
             + D S MK MNV+V+SC D SLGCSCGDCPSS VCS+S  P+  ++  C +++GSL+V 
Sbjct: 215  TVLDPSPMKLMNVSVYSCNDTSLGCSCGDCPSSPVCSDSE-PSPPRKDPCSIRIGSLKVR 273

Query: 1060 CLEFSLAVVYIVFISVLLLWGLLHRKRVKEGPSSKTNPLVN--VKDENEPVNKQETSIQP 1233
            C+EFSLA++YIV + VL  W LL R R + G  S   PL+N  V + +   N Q+    P
Sbjct: 274  CVEFSLAILYIVLVFVLFGWALLQRTRGRRGLGSSVEPLLNDMVGEGSSFANLQKNGTHP 333

Query: 1234 VQI----PEGPPAVQALQPSIVQRYMSSFFRKYGAFVSRKPLLILCLSVAVPLLLCIGLV 1401
             ++    P+G   VQ    S VQ  +SSF+R YG + +RKP ++LCLS+A+ +LL +GL+
Sbjct: 334  EEVQLIDPQGKNVVQF---SFVQGCLSSFYRTYGRWAARKPTVVLCLSLAIVVLLSLGLL 390

Query: 1402 RFKVETRPEKLWVGPGSKAAEEKKYFDYHLAPFYRIEELILATVPGSKDGKSPSIVSDEN 1581
            RF+VETRPEKLWVGPGSKAAEEK +FD HLAPFYRIE+LI+AT+P SK GK PSI+++EN
Sbjct: 391  RFEVETRPEKLWVGPGSKAAEEKDFFDSHLAPFYRIEQLIIATIPESKHGKPPSIITEEN 450

Query: 1582 MKLLFEIQKKIDGLKVNYSGSMISLSDICLKPLGDACATQSVLQYFKMDPENYNNYGGVE 1761
            ++LLFEIQ+K+DG++ NYSG ++SLSDICLKPLG+ CATQS+LQYF+MDP+NY+NYGGVE
Sbjct: 451  IELLFEIQEKVDGIRANYSGLLVSLSDICLKPLGEDCATQSILQYFQMDPDNYDNYGGVE 510

Query: 1762 HADYCFLHYSSAETCLSAFQAPLDPSTALGGFSGNNFSEASAFVITYPVNNEVERTGNEN 1941
            HA+YCF HY+S ETC SAF+APL+P+TALGGFSGNN+SEASAF+ITYPVNN   R G+EN
Sbjct: 511  HAEYCFQHYTSTETCFSAFKAPLEPTTALGGFSGNNYSEASAFIITYPVNNAFTRVGDEN 570

Query: 1942 GKAVAWEKAFVRLVKEEIGPMVKLQNLTLSFSSESSVQEELKRESSADVITILVSYLVMF 2121
            GKA+AWEKAF++L KEE+ PMV+ +NLTLSFS+ESS++EELKRES+ADVITILVSY+VMF
Sbjct: 571  GKAIAWEKAFIQLAKEELLPMVQSRNLTLSFSTESSIEEELKRESTADVITILVSYIVMF 630

Query: 2122 AYISFTLGDSPHXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXAIGVKSTLIIMEVIP 2301
            AYIS TLGD+P                                  AIGVKSTLIIMEVIP
Sbjct: 631  AYISVTLGDTPPHPCSFYLSSKVLLGLLGVLLVMLSVLGSVGFFSAIGVKSTLIIMEVIP 690

Query: 2302 FLVLAVGVDNMCILVHAFKRQPLDLPLEGRVSNALVEVGPSITLASLSEVLAFAVGSFIP 2481
            FLVLAVGVDNMCI+V A KRQPL LP+E ++S A+ EVGPSITLASLSE+LAFAVGSF+ 
Sbjct: 691  FLVLAVGVDNMCIIVDAVKRQPLGLPIEEKISGAMGEVGPSITLASLSEILAFAVGSFVS 750

Query: 2482 MPACRVFSMXXXXXXXXXXXXQVTAFVALIVLDFLRAEDYRIDCIPCVKVSLSD-ESNKG 2658
            MPACRVFSM            Q+TAFVAL+ LDF+RA+D RIDC PC+K+S S  E N+G
Sbjct: 751  MPACRVFSMIAALAVLLDFLLQITAFVALVTLDFVRAKDNRIDCFPCIKLSSSSTEQNEG 810

Query: 2659 DDPRNLGLVARYMKDVHAPMLEIPGVKMIVIAVFVAFSFASIDLCTRLQPGLEQQVVLPR 2838
            +     GL+ RYMK+VHAP L + GVK+ VIA+F AF+ ASI LCTR++PGLEQQ+ LPR
Sbjct: 811  NRQERDGLLTRYMKEVHAPFLGLWGVKISVIAIFAAFTLASIALCTRIEPGLEQQIALPR 870

Query: 2839 DSYLQDYFGDLAKYLRVGPPLYFVVKDFNYSLESEQTNQLCSISQCDSNSLLNEITRASL 3018
            DSYLQ YF ++++YLRVGPPLYFVVKD+NYSL S+ TNQLCSIS CDSNSLLNEI+RASL
Sbjct: 871  DSYLQGYFSNISEYLRVGPPLYFVVKDYNYSLGSKHTNQLCSISHCDSNSLLNEISRASL 930

Query: 3019 TAESSYIAKPAASWLDDFLIWLSPEAFSCCRKFVNGSYXXXXXXXXXXXXGDSSCGMGGI 3198
              ESSYIAKPAASWLDDFL+W+SPEAFSCCRKF NGSY             +  CG+GG+
Sbjct: 931  VPESSYIAKPAASWLDDFLVWISPEAFSCCRKFTNGSYCPPDDQPPCCFPDEGPCGLGGV 990

Query: 3199 CKDCTTCFRHSDLQDGRPSTSQFKEKLPWFLKALPSSNCAKGGNGAYTSSVDLTGYDSGI 3378
            CKDCTTCFRH DL + RPST+QF+EKLPWFL ALPS++CAKGG+GAYT+SVDL GY+ G+
Sbjct: 991  CKDCTTCFRHLDLVNDRPSTAQFREKLPWFLDALPSADCAKGGHGAYTNSVDLNGYEGGV 1050

Query: 3379 IQASSFRTYHTPLNKQSDYVNGMRAAREFSSEVSKSLKMQIFPYSVFYIFFEQYLDIWKT 3558
            IQAS FRTYHTPLN+Q DYVN +RAAR+FS+ +S SLKM IFPYSVFYIFFEQYLDIW  
Sbjct: 1051 IQASEFRTYHTPLNRQGDYVNAIRAARDFSARISTSLKMDIFPYSVFYIFFEQYLDIWML 1110

Query: 3559 ALVNILIGLGAVFIVCSVITCSFWTSTIILVVLAMIVIDMMGVMAILKIQLNAISVVNLV 3738
            AL+NI I LGA+F+VC VIT S W+S IIL+VL MI++++MGVMAIL IQLNA+SVVNL+
Sbjct: 1111 ALINIAIALGAIFVVCLVITSSLWSSAIILLVLVMIILELMGVMAILGIQLNAVSVVNLI 1170

Query: 3739 MSIGIAVEFCVHITHSFSVSCGDRGTRARAALCTMGASIFSGITLTKLVGVIVLRFARSE 3918
            MSIGIAVEFCVHI H+F VS GDR  RA+ ALCTMGAS+FSGITLTKLVGV+VL F+ SE
Sbjct: 1171 MSIGIAVEFCVHIVHAFMVSMGDRSQRAKTALCTMGASVFSGITLTKLVGVLVLCFSTSE 1230

Query: 3919 IFVVYYFQMYLALVLLGFLH 3978
            IFVVYYFQMYLALV++GFLH
Sbjct: 1231 IFVVYYFQMYLALVIIGFLH 1250


>ref|XP_004976504.2| Niemann-Pick C1 protein [Setaria italica]
          Length = 1291

 Score = 1677 bits (4344), Expect = 0.0
 Identities = 836/1247 (67%), Positives = 984/1247 (78%), Gaps = 3/1247 (0%)
 Frame = +1

Query: 247  IQVNLHVFSASAQDSHSHFRILAGARPEKISAEGYCSMYGICEKRSDGKPLNCPSNTPSV 426
            +Q++L  F  SAQ S+       G+R   + AEGYCSMYGIC +RSDGK LNC + T +V
Sbjct: 21   VQISLLAFPISAQQSN-------GSRV--VPAEGYCSMYGICAQRSDGKVLNCANATKAV 71

Query: 427  KPDKLLSSKVQSLCPTITGNVCCTADQFDTLRGQVQQAIPFLVGCPACLRNFLNVFCELS 606
            KPD L SS++QSLCPTITGNVCCTADQFDTL  QVQQA+PFLVGCPACLRNFLN+FCE+S
Sbjct: 72   KPDTLFSSRIQSLCPTITGNVCCTADQFDTLHQQVQQAVPFLVGCPACLRNFLNLFCEMS 131

Query: 607  CSPNQSLFINVTSVMKGSNTTTVDGIDLYITSTYGEALYNSCKDVKFGTMNTRAMDFIGG 786
            CSPNQSLFINVTSV + ++T TVDGID Y+T+ YGE LYNSCKDVKFGT+NTRAMDF+GG
Sbjct: 132  CSPNQSLFINVTSVKQINSTMTVDGIDYYVTTNYGEELYNSCKDVKFGTLNTRAMDFLGG 191

Query: 787  GAQNYNEWFAFIGKQAGVGEIGSPYAIDFRSNISDSSGMKPMNVTVHSCGDLSLGCSCGD 966
            GA+ Y EW AFIG+QA   E GSPY I FRS+ SDSSG+KP+N T++SCGD SLGCSCGD
Sbjct: 192  GAKTYKEWLAFIGRQANPNEPGSPYLITFRSDFSDSSGVKPLNSTIYSCGDPSLGCSCGD 251

Query: 967  CPSSSVCSESATPASHKQGSCHVKMGSLEVNCLEFSLAVVYIVFISVLLLWGLLHRKRVK 1146
            CPSSSVC+ S  P  +   SC VKMGSL+  CL+FSL V+Y+  +   LLWGLLHR R +
Sbjct: 252  CPSSSVCTGSLLPQLNTDTSCSVKMGSLKAKCLDFSLVVIYLALLCAFLLWGLLHRARGR 311

Query: 1147 EGPSSKTNPLVNVKDENEPVNKQETSIQPVQIPEGPPA-VQALQPSIVQRYMSSFFRKYG 1323
               S +T PL N  D+++     ++    VQ+ E   + V+   PSIVQ YMS FFRK+G
Sbjct: 312  TASSLQTKPLKNSDDKSDSNQNGKSPHNSVQVSEAASSTVKPSYPSIVQTYMSIFFRKHG 371

Query: 1324 AFVSRKPLLILCLSVAVPLLLCIGLVRFKVETRPEKLWVGPGSKAAEEKKYFDYHLAPFY 1503
             FV+R PLL+LC+S+ +PLLLCIGL+RFKVET+PEKLWV PGS+AA+EK YFD HLAPFY
Sbjct: 372  IFVARHPLLVLCVSLLIPLLLCIGLLRFKVETQPEKLWVSPGSRAADEKNYFDSHLAPFY 431

Query: 1504 RIEELILATVPGSKDGKSPSIVSDENMKLLFEIQKKIDGLKVNYSGSMISLSDICLKPLG 1683
            RIE+L+LAT   S    +PSIV+D NMKLLF+IQKK+D L+ +YSGS ++L+DICLKPL 
Sbjct: 432  RIEQLVLAT-SASSGSAAPSIVNDNNMKLLFQIQKKVDDLRASYSGSTVALADICLKPLS 490

Query: 1684 DACATQSVLQYFKMDPENYNNYGGVEHADYCFLHYSSAETCLSAFQAPLDPSTALGGFSG 1863
              CATQSVLQYF++DP+ Y++  G++HA +CF HY+S ETCLS FQ+P+DPST LGGFSG
Sbjct: 491  TDCATQSVLQYFQLDPKKYDD-SGIDHAKFCFQHYTSEETCLSTFQSPIDPSTILGGFSG 549

Query: 1864 NNFSEASAFVITYPVNNEVERTGNENGKAVAWEKAFVRLVKEEIGPMVKLQNLTLSFSSE 2043
            NNF+EASAFVITYPVNN+VE TG ENGKAVAWE+AF+ LVKEEI PMV  QNLTLSFSSE
Sbjct: 550  NNFTEASAFVITYPVNNKVETTGQENGKAVAWERAFINLVKEEILPMVLAQNLTLSFSSE 609

Query: 2044 SSVQEELKRESSADVITILVSYLVMFAYISFTLGDSPHXXXXXXXXXXXXXXXXXXXXXX 2223
            SS+Q+EL RES+AD ITI++SY+VMFAYISFTLGD P                       
Sbjct: 610  SSIQDELNRESTADAITIVISYIVMFAYISFTLGDRPSRWLSLFVSSKVLLGLSGVVLVM 669

Query: 2224 XXXXXXXXXXXAIGVKSTLIIMEVIPFLVLAVGVDNMCILVHAFKRQPLDLPLEGRVSNA 2403
                       AIGVKSTLIIMEVIPFLVLAVGVDNMCILVHA KRQP    LE R+S A
Sbjct: 670  LSVLGSMGFFSAIGVKSTLIIMEVIPFLVLAVGVDNMCILVHAVKRQPDQSNLEERISEA 729

Query: 2404 LVEVGPSITLASLSEVLAFAVGSFIPMPACRVFSMXXXXXXXXXXXXQVTAFVALIVLDF 2583
            LVEVGPSITLAS +EVLAFAV +  PMPA RVFSM            QVTAFVALIV DF
Sbjct: 730  LVEVGPSITLASFAEVLAFAVSAINPMPATRVFSMFAALAVFMDFLLQVTAFVALIVFDF 789

Query: 2584 LRAEDYRIDCIPCVKVSLSDESNKGDDPRNLGLVARYMKDVHAPMLEIPGVKMIVIAVFV 2763
             RA+D RIDC+PC +++ S  +  G D + L L+ARYM+D+H P+L    VK +VI VFV
Sbjct: 790  RRAQDGRIDCVPCARIASSPAAGDGGDGQRLHLLARYMRDIHGPILSYRAVKFVVITVFV 849

Query: 2764 AFSFASIDLCTRLQPGLEQQVVLPRDSYLQDYFGDLAKYLRVGPPLYFVVKDFNYSLESE 2943
              +F+SI L TRLQPGLEQQ+VLPR+SYLQDYF DLAKY++VGPPLYFVVKDFNYS  S 
Sbjct: 850  GLAFSSIALSTRLQPGLEQQIVLPRNSYLQDYFDDLAKYMKVGPPLYFVVKDFNYSSASV 909

Query: 2944 QTNQLCSISQCDSNSLLNEITRASLTAESSYIAKPAASWLDDFLIWLSPEAFSCCRKFVN 3123
             TNQ+CSI+QC+SNSLLNEI R SL+ E+SYIAKPAASWLDDFLIW+SPEAF CCRKFVN
Sbjct: 910  HTNQICSINQCNSNSLLNEIARQSLSPETSYIAKPAASWLDDFLIWMSPEAFGCCRKFVN 969

Query: 3124 GSYXXXXXXXXXXXXGDSS--CGMGGICKDCTTCFRHSDLQDGRPSTSQFKEKLPWFLKA 3297
            GSY               S  C     C +CTTCF HSDL +GRPST+QFK+KLPWFL A
Sbjct: 970  GSYCPPDDQPPCCQLDQDSGTCSASRTCSNCTTCFLHSDLDNGRPSTTQFKDKLPWFLDA 1029

Query: 3298 LPSSNCAKGGNGAYTSSVDLTGYDSGIIQASSFRTYHTPLNKQSDYVNGMRAAREFSSEV 3477
            LPSS+C+KGG GAY++S+DL GY+SGIIQAS+FRTYHTPLNKQ+DYVN MRAAR+FSS++
Sbjct: 1030 LPSSDCSKGGKGAYSTSLDLNGYESGIIQASAFRTYHTPLNKQTDYVNSMRAARDFSSKM 1089

Query: 3478 SKSLKMQIFPYSVFYIFFEQYLDIWKTALVNILIGLGAVFIVCSVITCSFWTSTIILVVL 3657
            SK L+M+IFPYSVFYIFFEQYL +WKTA++NI + LG +F+VC ++T S W S IIL+VL
Sbjct: 1090 SKDLQMEIFPYSVFYIFFEQYLGVWKTAIMNICVCLGTIFVVCFLVTSSLWASAIILIVL 1149

Query: 3658 AMIVIDMMGVMAILKIQLNAISVVNLVMSIGIAVEFCVHITHSFSVSCGDRGTRARAALC 3837
            AMIV+D+MGVMAIL IQLNAISVVNLVMSIGIAVEFCVHITH+F +  GDR TRAR AL 
Sbjct: 1150 AMIVLDLMGVMAILGIQLNAISVVNLVMSIGIAVEFCVHITHAFMIGTGDRETRARQALS 1209

Query: 3838 TMGASIFSGITLTKLVGVIVLRFARSEIFVVYYFQMYLALVLLGFLH 3978
            TMGAS+FSGITLTKLVGVIVLRFA+SE+FVVYYFQMYLALVL+GFLH
Sbjct: 1210 TMGASVFSGITLTKLVGVIVLRFAKSEVFVVYYFQMYLALVLIGFLH 1256


>gb|KQK98466.1| hypothetical protein SETIT_009194mg [Setaria italica]
          Length = 1272

 Score = 1677 bits (4342), Expect = 0.0
 Identities = 836/1247 (67%), Positives = 984/1247 (78%), Gaps = 3/1247 (0%)
 Frame = +1

Query: 247  IQVNLHVFSASAQDSHSHFRILAGARPEKISAEGYCSMYGICEKRSDGKPLNCPSNTPSV 426
            +Q++L  F  SAQ S+       G+R   + AEGYCSMYGIC +RSDGK LNC + T +V
Sbjct: 2    MQISLLAFPISAQQSN-------GSRV--VPAEGYCSMYGICAQRSDGKVLNCANATKAV 52

Query: 427  KPDKLLSSKVQSLCPTITGNVCCTADQFDTLRGQVQQAIPFLVGCPACLRNFLNVFCELS 606
            KPD L SS++QSLCPTITGNVCCTADQFDTL  QVQQA+PFLVGCPACLRNFLN+FCE+S
Sbjct: 53   KPDTLFSSRIQSLCPTITGNVCCTADQFDTLHQQVQQAVPFLVGCPACLRNFLNLFCEMS 112

Query: 607  CSPNQSLFINVTSVMKGSNTTTVDGIDLYITSTYGEALYNSCKDVKFGTMNTRAMDFIGG 786
            CSPNQSLFINVTSV + ++T TVDGID Y+T+ YGE LYNSCKDVKFGT+NTRAMDF+GG
Sbjct: 113  CSPNQSLFINVTSVKQINSTMTVDGIDYYVTTNYGEELYNSCKDVKFGTLNTRAMDFLGG 172

Query: 787  GAQNYNEWFAFIGKQAGVGEIGSPYAIDFRSNISDSSGMKPMNVTVHSCGDLSLGCSCGD 966
            GA+ Y EW AFIG+QA   E GSPY I FRS+ SDSSG+KP+N T++SCGD SLGCSCGD
Sbjct: 173  GAKTYKEWLAFIGRQANPNEPGSPYLITFRSDFSDSSGVKPLNSTIYSCGDPSLGCSCGD 232

Query: 967  CPSSSVCSESATPASHKQGSCHVKMGSLEVNCLEFSLAVVYIVFISVLLLWGLLHRKRVK 1146
            CPSSSVC+ S  P  +   SC VKMGSL+  CL+FSL V+Y+  +   LLWGLLHR R +
Sbjct: 233  CPSSSVCTGSLLPQLNTDTSCSVKMGSLKAKCLDFSLVVIYLALLCAFLLWGLLHRARGR 292

Query: 1147 EGPSSKTNPLVNVKDENEPVNKQETSIQPVQIPEGPPA-VQALQPSIVQRYMSSFFRKYG 1323
               S +T PL N  D+++     ++    VQ+ E   + V+   PSIVQ YMS FFRK+G
Sbjct: 293  TASSLQTKPLKNSDDKSDSNQNGKSPHNSVQVSEAASSTVKPSYPSIVQTYMSIFFRKHG 352

Query: 1324 AFVSRKPLLILCLSVAVPLLLCIGLVRFKVETRPEKLWVGPGSKAAEEKKYFDYHLAPFY 1503
             FV+R PLL+LC+S+ +PLLLCIGL+RFKVET+PEKLWV PGS+AA+EK YFD HLAPFY
Sbjct: 353  IFVARHPLLVLCVSLLIPLLLCIGLLRFKVETQPEKLWVSPGSRAADEKNYFDSHLAPFY 412

Query: 1504 RIEELILATVPGSKDGKSPSIVSDENMKLLFEIQKKIDGLKVNYSGSMISLSDICLKPLG 1683
            RIE+L+LAT   S    +PSIV+D NMKLLF+IQKK+D L+ +YSGS ++L+DICLKPL 
Sbjct: 413  RIEQLVLAT-SASSGSAAPSIVNDNNMKLLFQIQKKVDDLRASYSGSTVALADICLKPLS 471

Query: 1684 DACATQSVLQYFKMDPENYNNYGGVEHADYCFLHYSSAETCLSAFQAPLDPSTALGGFSG 1863
              CATQSVLQYF++DP+ Y++  G++HA +CF HY+S ETCLS FQ+P+DPST LGGFSG
Sbjct: 472  TDCATQSVLQYFQLDPKKYDD-SGIDHAKFCFQHYTSEETCLSTFQSPIDPSTILGGFSG 530

Query: 1864 NNFSEASAFVITYPVNNEVERTGNENGKAVAWEKAFVRLVKEEIGPMVKLQNLTLSFSSE 2043
            NNF+EASAFVITYPVNN+VE TG ENGKAVAWE+AF+ LVKEEI PMV  QNLTLSFSSE
Sbjct: 531  NNFTEASAFVITYPVNNKVETTGQENGKAVAWERAFINLVKEEILPMVLAQNLTLSFSSE 590

Query: 2044 SSVQEELKRESSADVITILVSYLVMFAYISFTLGDSPHXXXXXXXXXXXXXXXXXXXXXX 2223
            SS+Q+EL RES+AD ITI++SY+VMFAYISFTLGD P                       
Sbjct: 591  SSIQDELNRESTADAITIVISYIVMFAYISFTLGDRPSRWLSLFVSSKVLLGLSGVVLVM 650

Query: 2224 XXXXXXXXXXXAIGVKSTLIIMEVIPFLVLAVGVDNMCILVHAFKRQPLDLPLEGRVSNA 2403
                       AIGVKSTLIIMEVIPFLVLAVGVDNMCILVHA KRQP    LE R+S A
Sbjct: 651  LSVLGSMGFFSAIGVKSTLIIMEVIPFLVLAVGVDNMCILVHAVKRQPDQSNLEERISEA 710

Query: 2404 LVEVGPSITLASLSEVLAFAVGSFIPMPACRVFSMXXXXXXXXXXXXQVTAFVALIVLDF 2583
            LVEVGPSITLAS +EVLAFAV +  PMPA RVFSM            QVTAFVALIV DF
Sbjct: 711  LVEVGPSITLASFAEVLAFAVSAINPMPATRVFSMFAALAVFMDFLLQVTAFVALIVFDF 770

Query: 2584 LRAEDYRIDCIPCVKVSLSDESNKGDDPRNLGLVARYMKDVHAPMLEIPGVKMIVIAVFV 2763
             RA+D RIDC+PC +++ S  +  G D + L L+ARYM+D+H P+L    VK +VI VFV
Sbjct: 771  RRAQDGRIDCVPCARIASSPAAGDGGDGQRLHLLARYMRDIHGPILSYRAVKFVVITVFV 830

Query: 2764 AFSFASIDLCTRLQPGLEQQVVLPRDSYLQDYFGDLAKYLRVGPPLYFVVKDFNYSLESE 2943
              +F+SI L TRLQPGLEQQ+VLPR+SYLQDYF DLAKY++VGPPLYFVVKDFNYS  S 
Sbjct: 831  GLAFSSIALSTRLQPGLEQQIVLPRNSYLQDYFDDLAKYMKVGPPLYFVVKDFNYSSASV 890

Query: 2944 QTNQLCSISQCDSNSLLNEITRASLTAESSYIAKPAASWLDDFLIWLSPEAFSCCRKFVN 3123
             TNQ+CSI+QC+SNSLLNEI R SL+ E+SYIAKPAASWLDDFLIW+SPEAF CCRKFVN
Sbjct: 891  HTNQICSINQCNSNSLLNEIARQSLSPETSYIAKPAASWLDDFLIWMSPEAFGCCRKFVN 950

Query: 3124 GSYXXXXXXXXXXXXGDSS--CGMGGICKDCTTCFRHSDLQDGRPSTSQFKEKLPWFLKA 3297
            GSY               S  C     C +CTTCF HSDL +GRPST+QFK+KLPWFL A
Sbjct: 951  GSYCPPDDQPPCCQLDQDSGTCSASRTCSNCTTCFLHSDLDNGRPSTTQFKDKLPWFLDA 1010

Query: 3298 LPSSNCAKGGNGAYTSSVDLTGYDSGIIQASSFRTYHTPLNKQSDYVNGMRAAREFSSEV 3477
            LPSS+C+KGG GAY++S+DL GY+SGIIQAS+FRTYHTPLNKQ+DYVN MRAAR+FSS++
Sbjct: 1011 LPSSDCSKGGKGAYSTSLDLNGYESGIIQASAFRTYHTPLNKQTDYVNSMRAARDFSSKM 1070

Query: 3478 SKSLKMQIFPYSVFYIFFEQYLDIWKTALVNILIGLGAVFIVCSVITCSFWTSTIILVVL 3657
            SK L+M+IFPYSVFYIFFEQYL +WKTA++NI + LG +F+VC ++T S W S IIL+VL
Sbjct: 1071 SKDLQMEIFPYSVFYIFFEQYLGVWKTAIMNICVCLGTIFVVCFLVTSSLWASAIILIVL 1130

Query: 3658 AMIVIDMMGVMAILKIQLNAISVVNLVMSIGIAVEFCVHITHSFSVSCGDRGTRARAALC 3837
            AMIV+D+MGVMAIL IQLNAISVVNLVMSIGIAVEFCVHITH+F +  GDR TRAR AL 
Sbjct: 1131 AMIVLDLMGVMAILGIQLNAISVVNLVMSIGIAVEFCVHITHAFMIGTGDRETRARQALS 1190

Query: 3838 TMGASIFSGITLTKLVGVIVLRFARSEIFVVYYFQMYLALVLLGFLH 3978
            TMGAS+FSGITLTKLVGVIVLRFA+SE+FVVYYFQMYLALVL+GFLH
Sbjct: 1191 TMGASVFSGITLTKLVGVIVLRFAKSEVFVVYYFQMYLALVLIGFLH 1237


>gb|KRH14018.1| hypothetical protein GLYMA_14G001500 [Glycine max]
          Length = 1284

 Score = 1670 bits (4325), Expect = 0.0
 Identities = 821/1240 (66%), Positives = 988/1240 (79%), Gaps = 4/1240 (0%)
 Frame = +1

Query: 271  SASAQDSHSHFRILAGARPEKISAEGYCSMYGICEKRSDGKPLNCPSNTPSVKPDKLLSS 450
            S+ A   H  FR           +E YC+MY IC + SDGK LNCP  +PSVKPD LLS+
Sbjct: 18   SSPATSQHETFRAK--------HSEEYCAMYDICGQSSDGKALNCPYGSPSVKPDDLLSA 69

Query: 451  KVQSLCPTITGNVCCTADQFDTLRGQVQQAIPFLVGCPACLRNFLNVFCELSCSPNQSLF 630
            K+QSLCPTITGNVCCTADQFDTLR QVQQA+P LVGCPACLRNFLN+FCELSCSPNQSLF
Sbjct: 70   KIQSLCPTITGNVCCTADQFDTLRVQVQQAVPILVGCPACLRNFLNLFCELSCSPNQSLF 129

Query: 631  INVTSVMKGSNTTTVDGIDLYITSTYGEALYNSCKDVKFGTMNTRAMDFIGGGAQNYNEW 810
            INVTS+ + +   TVDGID YIT T+GE LY SCKDVKFGTMNTRA+DF+G GA N+ EW
Sbjct: 130  INVTSISEVNGNMTVDGIDYYITETFGEGLYESCKDVKFGTMNTRAIDFVGAGASNFKEW 189

Query: 811  FAFIGKQAGVGEIGSPYAIDFRSNISDSSGMKPMNVTVHSCGDLSLGCSCGDCPSSSVCS 990
            FAF+G++   G  GSPY+I F++ I DSS MK MN +V+SC D SLGCSCGDCPSS VCS
Sbjct: 190  FAFLGQKVPPGFPGSPYSILFKTTILDSSPMKLMNASVYSCNDTSLGCSCGDCPSSPVCS 249

Query: 991  ESATPASHKQGSCHVKMGSLEVNCLEFSLAVVYIVFISVLLLWGLLHRKRVKEGPSSKTN 1170
             S  P+  ++  C +++GSL+V C++FS+A++YIV + VL  W LL R R +    S   
Sbjct: 250  GSE-PSPPRKDPCSIRIGSLKVRCVDFSMAILYIVLVFVLFGWALLQRTRGRRRLGSGVE 308

Query: 1171 PLVN--VKDENEPVNKQETSIQPVQI-PEGPPAVQALQPSIVQRYMSSFFRKYGAFVSRK 1341
            PL++  V + +   N Q+    P +I P+G   VQ    S VQ  +SSF+R YG + +RK
Sbjct: 309  PLLDDMVDEGSSFANLQKDGTHPAEIDPQGQNVVQF---SFVQGCLSSFYRTYGRWATRK 365

Query: 1342 PLLILCLSVAVPLLLCIGLVRFKVETRPEKLWVGPGSKAAEEKKYFDYHLAPFYRIEELI 1521
            P ++LC S+ + +LLC+GL+RF+VETRPEKLWVGPGSKAAEEK++FD HLAPFYRIE+LI
Sbjct: 366  PTIVLCSSLTIVVLLCLGLLRFEVETRPEKLWVGPGSKAAEEKEFFDSHLAPFYRIEQLI 425

Query: 1522 LATVPGSKDGKSPSIVSDENMKLLFEIQKKIDGLKVNYSGSMISLSDICLKPLGDACATQ 1701
            +AT+P SK GK PSI+++EN++LLFEIQ+K+DG++ NYSG ++SLSDICLKPLGD CA+Q
Sbjct: 426  IATIPESKHGKPPSIITEENIELLFEIQEKVDGIRANYSGLLVSLSDICLKPLGDDCASQ 485

Query: 1702 SVLQYFKMDPENYNNYGGVEHADYCFLHYSSAETCLSAFQAPLDPSTALGGFSGNNFSEA 1881
            S+LQYF+MDP+NY+NYGGVEHA+YCF HY+S ETC SAF+APL+P+TALGGFSGNN+SEA
Sbjct: 486  SILQYFQMDPDNYDNYGGVEHAEYCFQHYTSTETCFSAFKAPLEPTTALGGFSGNNYSEA 545

Query: 1882 SAFVITYPVNNEVERTGNENGKAVAWEKAFVRLVKEEIGPMVKLQNLTLSFSSESSVQEE 2061
            SAFVITYPVNN + + G+ENGKA+AWEKAF++L KEE+ PMV+  NLTLSFS+ESS++EE
Sbjct: 546  SAFVITYPVNNAITKVGDENGKAIAWEKAFIQLAKEELLPMVQSSNLTLSFSTESSIEEE 605

Query: 2062 LKRESSADVITILVSYLVMFAYISFTLGDSPHXXXXXXXXXXXXXXXXXXXXXXXXXXXX 2241
            LKRES+ADVITILVSY+VMFAYIS TLGD P                             
Sbjct: 606  LKRESTADVITILVSYIVMFAYISVTLGDRPPHPSSLFLSSKVLLGLLGVLLVMLSVLGS 665

Query: 2242 XXXXXAIGVKSTLIIMEVIPFLVLAVGVDNMCILVHAFKRQPLDLPLEGRVSNALVEVGP 2421
                 AIGVKSTLIIMEVIPFLVLAVGVDNMCI+V A KRQP  LP+E ++SNA+ EVGP
Sbjct: 666  VGFFSAIGVKSTLIIMEVIPFLVLAVGVDNMCIIVDAVKRQPSGLPVEEQISNAMGEVGP 725

Query: 2422 SITLASLSEVLAFAVGSFIPMPACRVFSMXXXXXXXXXXXXQVTAFVALIVLDFLRAEDY 2601
            SITLASLSE+LAFAVGSF+ MPACRVFSM            Q+TAFVAL+ LDF+RA+D 
Sbjct: 726  SITLASLSEILAFAVGSFVSMPACRVFSMIAALAVLLDFLLQITAFVALVTLDFMRAKDN 785

Query: 2602 RIDCIPCVKVSL-SDESNKGDDPRNLGLVARYMKDVHAPMLEIPGVKMIVIAVFVAFSFA 2778
            RIDC PC+K++  S E N+G      GL+ RYMK+VHAP L + GVK++VIAVF AF+ A
Sbjct: 786  RIDCFPCMKLNPPSAERNEGVRRERDGLLTRYMKEVHAPFLGLCGVKILVIAVFAAFTLA 845

Query: 2779 SIDLCTRLQPGLEQQVVLPRDSYLQDYFGDLAKYLRVGPPLYFVVKDFNYSLESEQTNQL 2958
            SI LCTR++PGLEQQ+ LPRDSYLQ YF ++++YLRVGPPLYFVVKD+NYSLES+ TNQL
Sbjct: 846  SIALCTRIEPGLEQQIALPRDSYLQGYFSNISEYLRVGPPLYFVVKDYNYSLESKHTNQL 905

Query: 2959 CSISQCDSNSLLNEITRASLTAESSYIAKPAASWLDDFLIWLSPEAFSCCRKFVNGSYXX 3138
            CSIS CDSNSLLNEI+RASL   SSYIAKPAASWLDDFL+W+SPEAFSCCRKF N SY  
Sbjct: 906  CSISHCDSNSLLNEISRASLVPTSSYIAKPAASWLDDFLVWISPEAFSCCRKFTNDSYCP 965

Query: 3139 XXXXXXXXXXGDSSCGMGGICKDCTTCFRHSDLQDGRPSTSQFKEKLPWFLKALPSSNCA 3318
                       +  CG+GG+CKDCTTCFRHSDL + RPST+QF+EKLPWFL ALPS++CA
Sbjct: 966  PDDQPPCCLPDEGPCGLGGVCKDCTTCFRHSDLVNDRPSTAQFREKLPWFLDALPSADCA 1025

Query: 3319 KGGNGAYTSSVDLTGYDSGIIQASSFRTYHTPLNKQSDYVNGMRAAREFSSEVSKSLKMQ 3498
            KGG+GAYT+SVDL GY+ G+IQAS FRTYHTP+N+Q DYVN +RAAR+FS+ +S SLKM 
Sbjct: 1026 KGGHGAYTNSVDLNGYEGGVIQASEFRTYHTPVNRQGDYVNAIRAARDFSARISSSLKMD 1085

Query: 3499 IFPYSVFYIFFEQYLDIWKTALVNILIGLGAVFIVCSVITCSFWTSTIILVVLAMIVIDM 3678
            IFPYSVFYIFFEQYLDIWK AL+NI I LGA+F+VC +IT S W+S IIL+VL MI++D+
Sbjct: 1086 IFPYSVFYIFFEQYLDIWKLALINISIALGAIFVVCLIITSSVWSSVIILLVLIMIILDL 1145

Query: 3679 MGVMAILKIQLNAISVVNLVMSIGIAVEFCVHITHSFSVSCGDRGTRARAALCTMGASIF 3858
            MGVMAIL IQLNA+SVVNL+MSIGIAVEFCVHI H+F+VS GDR  RA+ ALCTMGAS+F
Sbjct: 1146 MGVMAILGIQLNAVSVVNLIMSIGIAVEFCVHIVHAFTVSLGDRSQRAKTALCTMGASVF 1205

Query: 3859 SGITLTKLVGVIVLRFARSEIFVVYYFQMYLALVLLGFLH 3978
            SGITLTKLVGV+VL F+ S+IFVVYYFQMYLALVL+GFLH
Sbjct: 1206 SGITLTKLVGVLVLCFSTSQIFVVYYFQMYLALVLIGFLH 1245


>ref|XP_006595638.1| PREDICTED: Niemann-Pick C1 protein isoform X2 [Glycine max]
 gb|KRH14017.1| hypothetical protein GLYMA_14G001500 [Glycine max]
          Length = 1287

 Score = 1670 bits (4325), Expect = 0.0
 Identities = 819/1240 (66%), Positives = 988/1240 (79%), Gaps = 4/1240 (0%)
 Frame = +1

Query: 271  SASAQDSHSHFRILAGARPEKISAEGYCSMYGICEKRSDGKPLNCPSNTPSVKPDKLLSS 450
            S+ A   H  FR           +E YC+MY IC + SDGK LNCP  +PSVKPD LLS+
Sbjct: 18   SSPATSQHETFRAK--------HSEEYCAMYDICGQSSDGKALNCPYGSPSVKPDDLLSA 69

Query: 451  KVQSLCPTITGNVCCTADQFDTLRGQVQQAIPFLVGCPACLRNFLNVFCELSCSPNQSLF 630
            K+QSLCPTITGNVCCTADQFDTLR QVQQA+P LVGCPACLRNFLN+FCELSCSPNQSLF
Sbjct: 70   KIQSLCPTITGNVCCTADQFDTLRVQVQQAVPILVGCPACLRNFLNLFCELSCSPNQSLF 129

Query: 631  INVTSVMKGSNTTTVDGIDLYITSTYGEALYNSCKDVKFGTMNTRAMDFIGGGAQNYNEW 810
            INVTS+ + +   TVDGID YIT T+GE LY SCKDVKFGTMNTRA+DF+G GA N+ EW
Sbjct: 130  INVTSISEVNGNMTVDGIDYYITETFGEGLYESCKDVKFGTMNTRAIDFVGAGASNFKEW 189

Query: 811  FAFIGKQAGVGEIGSPYAIDFRSNISDSSGMKPMNVTVHSCGDLSLGCSCGDCPSSSVCS 990
            FAF+G++   G  GSPY+I F++ I DSS MK MN +V+SC D SLGCSCGDCPSS VCS
Sbjct: 190  FAFLGQKVPPGFPGSPYSILFKTTILDSSPMKLMNASVYSCNDTSLGCSCGDCPSSPVCS 249

Query: 991  ESATPASHKQGSCHVKMGSLEVNCLEFSLAVVYIVFISVLLLWGLLHRKRVKEGPSSKTN 1170
             S  P+  ++  C +++GSL+V C++FS+A++YIV + VL  W LL R R +    S   
Sbjct: 250  GSE-PSPPRKDPCSIRIGSLKVRCVDFSMAILYIVLVFVLFGWALLQRTRGRRRLGSGVE 308

Query: 1171 PLVN--VKDENEPVNKQETSIQPVQIPEGPPAVQ-ALQPSIVQRYMSSFFRKYGAFVSRK 1341
            PL++  V + +   N Q+    P ++ +  P  Q  +Q S VQ  +SSF+R YG + +RK
Sbjct: 309  PLLDDMVDEGSSFANLQKDGTHPAEVQQIDPQGQNVVQFSFVQGCLSSFYRTYGRWATRK 368

Query: 1342 PLLILCLSVAVPLLLCIGLVRFKVETRPEKLWVGPGSKAAEEKKYFDYHLAPFYRIEELI 1521
            P ++LC S+ + +LLC+GL+RF+VETRPEKLWVGPGSKAAEEK++FD HLAPFYRIE+LI
Sbjct: 369  PTIVLCSSLTIVVLLCLGLLRFEVETRPEKLWVGPGSKAAEEKEFFDSHLAPFYRIEQLI 428

Query: 1522 LATVPGSKDGKSPSIVSDENMKLLFEIQKKIDGLKVNYSGSMISLSDICLKPLGDACATQ 1701
            +AT+P SK GK PSI+++EN++LLFEIQ+K+DG++ NYSG ++SLSDICLKPLGD CA+Q
Sbjct: 429  IATIPESKHGKPPSIITEENIELLFEIQEKVDGIRANYSGLLVSLSDICLKPLGDDCASQ 488

Query: 1702 SVLQYFKMDPENYNNYGGVEHADYCFLHYSSAETCLSAFQAPLDPSTALGGFSGNNFSEA 1881
            S+LQYF+MDP+NY+NYGGVEHA+YCF HY+S ETC SAF+APL+P+TALGGFSGNN+SEA
Sbjct: 489  SILQYFQMDPDNYDNYGGVEHAEYCFQHYTSTETCFSAFKAPLEPTTALGGFSGNNYSEA 548

Query: 1882 SAFVITYPVNNEVERTGNENGKAVAWEKAFVRLVKEEIGPMVKLQNLTLSFSSESSVQEE 2061
            SAFVITYPVNN + + G+ENGKA+AWEKAF++L KEE+ PMV+  NLTLSFS+ESS++EE
Sbjct: 549  SAFVITYPVNNAITKVGDENGKAIAWEKAFIQLAKEELLPMVQSSNLTLSFSTESSIEEE 608

Query: 2062 LKRESSADVITILVSYLVMFAYISFTLGDSPHXXXXXXXXXXXXXXXXXXXXXXXXXXXX 2241
            LKRES+ADVITILVSY+VMFAYIS TLGD P                             
Sbjct: 609  LKRESTADVITILVSYIVMFAYISVTLGDRPPHPSSLFLSSKVLLGLLGVLLVMLSVLGS 668

Query: 2242 XXXXXAIGVKSTLIIMEVIPFLVLAVGVDNMCILVHAFKRQPLDLPLEGRVSNALVEVGP 2421
                 AIGVKSTLIIMEVIPFLVLAVGVDNMCI+V A KRQP  LP+E ++SNA+ EVGP
Sbjct: 669  VGFFSAIGVKSTLIIMEVIPFLVLAVGVDNMCIIVDAVKRQPSGLPVEEQISNAMGEVGP 728

Query: 2422 SITLASLSEVLAFAVGSFIPMPACRVFSMXXXXXXXXXXXXQVTAFVALIVLDFLRAEDY 2601
            SITLASLSE+LAFAVGSF+ MPACRVFSM            Q+TAFVAL+ LDF+RA+D 
Sbjct: 729  SITLASLSEILAFAVGSFVSMPACRVFSMIAALAVLLDFLLQITAFVALVTLDFMRAKDN 788

Query: 2602 RIDCIPCVKVSL-SDESNKGDDPRNLGLVARYMKDVHAPMLEIPGVKMIVIAVFVAFSFA 2778
            RIDC PC+K++  S E N+G      GL+ RYMK+VHAP L + GVK++VIAVF AF+ A
Sbjct: 789  RIDCFPCMKLNPPSAERNEGVRRERDGLLTRYMKEVHAPFLGLCGVKILVIAVFAAFTLA 848

Query: 2779 SIDLCTRLQPGLEQQVVLPRDSYLQDYFGDLAKYLRVGPPLYFVVKDFNYSLESEQTNQL 2958
            SI LCTR++PGLEQQ+ LPRDSYLQ YF ++++YLRVGPPLYFVVKD+NYSLES+ TNQL
Sbjct: 849  SIALCTRIEPGLEQQIALPRDSYLQGYFSNISEYLRVGPPLYFVVKDYNYSLESKHTNQL 908

Query: 2959 CSISQCDSNSLLNEITRASLTAESSYIAKPAASWLDDFLIWLSPEAFSCCRKFVNGSYXX 3138
            CSIS CDSNSLLNEI+RASL   SSYIAKPAASWLDDFL+W+SPEAFSCCRKF N SY  
Sbjct: 909  CSISHCDSNSLLNEISRASLVPTSSYIAKPAASWLDDFLVWISPEAFSCCRKFTNDSYCP 968

Query: 3139 XXXXXXXXXXGDSSCGMGGICKDCTTCFRHSDLQDGRPSTSQFKEKLPWFLKALPSSNCA 3318
                       +  CG+GG+CKDCTTCFRHSDL + RPST+QF+EKLPWFL ALPS++CA
Sbjct: 969  PDDQPPCCLPDEGPCGLGGVCKDCTTCFRHSDLVNDRPSTAQFREKLPWFLDALPSADCA 1028

Query: 3319 KGGNGAYTSSVDLTGYDSGIIQASSFRTYHTPLNKQSDYVNGMRAAREFSSEVSKSLKMQ 3498
            KGG+GAYT+SVDL GY+ G+IQAS FRTYHTP+N+Q DYVN +RAAR+FS+ +S SLKM 
Sbjct: 1029 KGGHGAYTNSVDLNGYEGGVIQASEFRTYHTPVNRQGDYVNAIRAARDFSARISSSLKMD 1088

Query: 3499 IFPYSVFYIFFEQYLDIWKTALVNILIGLGAVFIVCSVITCSFWTSTIILVVLAMIVIDM 3678
            IFPYSVFYIFFEQYLDIWK AL+NI I LGA+F+VC +IT S W+S IIL+VL MI++D+
Sbjct: 1089 IFPYSVFYIFFEQYLDIWKLALINISIALGAIFVVCLIITSSVWSSVIILLVLIMIILDL 1148

Query: 3679 MGVMAILKIQLNAISVVNLVMSIGIAVEFCVHITHSFSVSCGDRGTRARAALCTMGASIF 3858
            MGVMAIL IQLNA+SVVNL+MSIGIAVEFCVHI H+F+VS GDR  RA+ ALCTMGAS+F
Sbjct: 1149 MGVMAILGIQLNAVSVVNLIMSIGIAVEFCVHIVHAFTVSLGDRSQRAKTALCTMGASVF 1208

Query: 3859 SGITLTKLVGVIVLRFARSEIFVVYYFQMYLALVLLGFLH 3978
            SGITLTKLVGV+VL F+ S+IFVVYYFQMYLALVL+GFLH
Sbjct: 1209 SGITLTKLVGVLVLCFSTSQIFVVYYFQMYLALVLIGFLH 1248


>ref|XP_006595637.1| PREDICTED: Niemann-Pick C1 protein isoform X1 [Glycine max]
          Length = 1289

 Score = 1668 bits (4319), Expect = 0.0
 Identities = 820/1242 (66%), Positives = 989/1242 (79%), Gaps = 6/1242 (0%)
 Frame = +1

Query: 271  SASAQDSHSHFRILAGARPEKISAEGYCSMYGICEKRSDGKPLNCPSNTPSVKPDKLLSS 450
            S+ A   H  FR           +E YC+MY IC + SDGK LNCP  +PSVKPD LLS+
Sbjct: 18   SSPATSQHETFRAK--------HSEEYCAMYDICGQSSDGKALNCPYGSPSVKPDDLLSA 69

Query: 451  KVQSLCPTITGNVCCTADQFDTLRGQVQQAIPFLVGCPACLRNFLNVFCELSCSPNQSLF 630
            K+QSLCPTITGNVCCTADQFDTLR QVQQA+P LVGCPACLRNFLN+FCELSCSPNQSLF
Sbjct: 70   KIQSLCPTITGNVCCTADQFDTLRVQVQQAVPILVGCPACLRNFLNLFCELSCSPNQSLF 129

Query: 631  INVTSVMKGSNTTTVDGIDLYITSTYGEALYNSCKDVKFGTMNTRAMDFIGGGAQNYNEW 810
            INVTS+ + +   TVDGID YIT T+GE LY SCKDVKFGTMNTRA+DF+G GA N+ EW
Sbjct: 130  INVTSISEVNGNMTVDGIDYYITETFGEGLYESCKDVKFGTMNTRAIDFVGAGASNFKEW 189

Query: 811  FAFIGKQAGVGEIGSPYAIDFRSNISDSSGMKPMNVTVHSCGDLSLGCSCGDCPSSSVCS 990
            FAF+G++   G  GSPY+I F++ I DSS MK MN +V+SC D SLGCSCGDCPSS VCS
Sbjct: 190  FAFLGQKVPPGFPGSPYSILFKTTILDSSPMKLMNASVYSCNDTSLGCSCGDCPSSPVCS 249

Query: 991  ESATPASHKQGSCHVKMGSLEVNCLEFSLAVVYIVFISVLLLWGLLHRKRVKEGPSSKTN 1170
             S  P+  ++  C +++GSL+V C++FS+A++YIV + VL  W LL R R +    S   
Sbjct: 250  GSE-PSPPRKDPCSIRIGSLKVRCVDFSMAILYIVLVFVLFGWALLQRTRGRRRLGSGVE 308

Query: 1171 PLVN--VKDENEPVNKQETSIQPVQIPEGPPAVQ-ALQPSIVQRYMSSFFRKYGAFVSRK 1341
            PL++  V + +   N Q+    P ++ +  P  Q  +Q S VQ  +SSF+R YG + +RK
Sbjct: 309  PLLDDMVDEGSSFANLQKDGTHPAEVQQIDPQGQNVVQFSFVQGCLSSFYRTYGRWATRK 368

Query: 1342 PLLILCLSVAVPLLLCIGLVRFKVETRPEKLWVGPGSKAAEEKKYFDYHLAPFYRIEELI 1521
            P ++LC S+ + +LLC+GL+RF+VETRPEKLWVGPGSKAAEEK++FD HLAPFYRIE+LI
Sbjct: 369  PTIVLCSSLTIVVLLCLGLLRFEVETRPEKLWVGPGSKAAEEKEFFDSHLAPFYRIEQLI 428

Query: 1522 LATVPGSKDGKSPSIVSDENMKLLFEIQKKIDGLKVNYSGSMISLSDICLKPLGDACATQ 1701
            +AT+P SK GK PSI+++EN++LLFEIQ+K+DG++ NYSG ++SLSDICLKPLGD CA+Q
Sbjct: 429  IATIPESKHGKPPSIITEENIELLFEIQEKVDGIRANYSGLLVSLSDICLKPLGDDCASQ 488

Query: 1702 SVLQYFKMDPENYNNYGGVEHADYCFLHYSSAETCLSAFQAPLDPSTALGGFSGNNFSEA 1881
            S+LQYF+MDP+NY+NYGGVEHA+YCF HY+S ETC SAF+APL+P+TALGGFSGNN+SEA
Sbjct: 489  SILQYFQMDPDNYDNYGGVEHAEYCFQHYTSTETCFSAFKAPLEPTTALGGFSGNNYSEA 548

Query: 1882 SAFVITYPVNNEVERTGNENGKAVAWEKAFVRLVKEEIGPMVKLQNLTLSFSSESSVQEE 2061
            SAFVITYPVNN + + G+ENGKA+AWEKAF++L KEE+ PMV+  NLTLSFS+ESS++EE
Sbjct: 549  SAFVITYPVNNAITKVGDENGKAIAWEKAFIQLAKEELLPMVQSSNLTLSFSTESSIEEE 608

Query: 2062 LKRESSADVITILVSYLVMFAYISFTLGDSPHXXXXXXXXXXXXXXXXXXXXXXXXXXXX 2241
            LKRES+ADVITILVSY+VMFAYIS TLGD P                             
Sbjct: 609  LKRESTADVITILVSYIVMFAYISVTLGDRPPHPSSLFLSSKVLLGLLGVLLVMLSVLGS 668

Query: 2242 XXXXXAIGVKSTLIIMEVIPFLVLAVGVDNMCILVHAFKRQPLDLPLEGRVSNALVEVGP 2421
                 AIGVKSTLIIMEVIPFLVLAVGVDNMCI+V A KRQP  LP+E ++SNA+ EVGP
Sbjct: 669  VGFFSAIGVKSTLIIMEVIPFLVLAVGVDNMCIIVDAVKRQPSGLPVEEQISNAMGEVGP 728

Query: 2422 SITLASLSEVLAFAVGSFIPMPACRVFSMXXXXXXXXXXXXQVTAFVALIVLDFLRAEDY 2601
            SITLASLSE+LAFAVGSF+ MPACRVFSM            Q+TAFVAL+ LDF+RA+D 
Sbjct: 729  SITLASLSEILAFAVGSFVSMPACRVFSMIAALAVLLDFLLQITAFVALVTLDFMRAKDN 788

Query: 2602 RIDCIPCVKVSL-SDESNKGDDPRNL--GLVARYMKDVHAPMLEIPGVKMIVIAVFVAFS 2772
            RIDC PC+K++  S E N+G   R    GL+ RYMK+VHAP L + GVK++VIAVF AF+
Sbjct: 789  RIDCFPCMKLNPPSAERNEGTCVRRERDGLLTRYMKEVHAPFLGLCGVKILVIAVFAAFT 848

Query: 2773 FASIDLCTRLQPGLEQQVVLPRDSYLQDYFGDLAKYLRVGPPLYFVVKDFNYSLESEQTN 2952
             ASI LCTR++PGLEQQ+ LPRDSYLQ YF ++++YLRVGPPLYFVVKD+NYSLES+ TN
Sbjct: 849  LASIALCTRIEPGLEQQIALPRDSYLQGYFSNISEYLRVGPPLYFVVKDYNYSLESKHTN 908

Query: 2953 QLCSISQCDSNSLLNEITRASLTAESSYIAKPAASWLDDFLIWLSPEAFSCCRKFVNGSY 3132
            QLCSIS CDSNSLLNEI+RASL   SSYIAKPAASWLDDFL+W+SPEAFSCCRKF N SY
Sbjct: 909  QLCSISHCDSNSLLNEISRASLVPTSSYIAKPAASWLDDFLVWISPEAFSCCRKFTNDSY 968

Query: 3133 XXXXXXXXXXXXGDSSCGMGGICKDCTTCFRHSDLQDGRPSTSQFKEKLPWFLKALPSSN 3312
                         +  CG+GG+CKDCTTCFRHSDL + RPST+QF+EKLPWFL ALPS++
Sbjct: 969  CPPDDQPPCCLPDEGPCGLGGVCKDCTTCFRHSDLVNDRPSTAQFREKLPWFLDALPSAD 1028

Query: 3313 CAKGGNGAYTSSVDLTGYDSGIIQASSFRTYHTPLNKQSDYVNGMRAAREFSSEVSKSLK 3492
            CAKGG+GAYT+SVDL GY+ G+IQAS FRTYHTP+N+Q DYVN +RAAR+FS+ +S SLK
Sbjct: 1029 CAKGGHGAYTNSVDLNGYEGGVIQASEFRTYHTPVNRQGDYVNAIRAARDFSARISSSLK 1088

Query: 3493 MQIFPYSVFYIFFEQYLDIWKTALVNILIGLGAVFIVCSVITCSFWTSTIILVVLAMIVI 3672
            M IFPYSVFYIFFEQYLDIWK AL+NI I LGA+F+VC +IT S W+S IIL+VL MI++
Sbjct: 1089 MDIFPYSVFYIFFEQYLDIWKLALINISIALGAIFVVCLIITSSVWSSVIILLVLIMIIL 1148

Query: 3673 DMMGVMAILKIQLNAISVVNLVMSIGIAVEFCVHITHSFSVSCGDRGTRARAALCTMGAS 3852
            D+MGVMAIL IQLNA+SVVNL+MSIGIAVEFCVHI H+F+VS GDR  RA+ ALCTMGAS
Sbjct: 1149 DLMGVMAILGIQLNAVSVVNLIMSIGIAVEFCVHIVHAFTVSLGDRSQRAKTALCTMGAS 1208

Query: 3853 IFSGITLTKLVGVIVLRFARSEIFVVYYFQMYLALVLLGFLH 3978
            +FSGITLTKLVGV+VL F+ S+IFVVYYFQMYLALVL+GFLH
Sbjct: 1209 VFSGITLTKLVGVLVLCFSTSQIFVVYYFQMYLALVLIGFLH 1250


>ref|XP_006575763.1| PREDICTED: Niemann-Pick C1 protein-like isoform X1 [Glycine max]
          Length = 1268

 Score = 1658 bits (4294), Expect = 0.0
 Identities = 811/1220 (66%), Positives = 978/1220 (80%), Gaps = 7/1220 (0%)
 Frame = +1

Query: 340  AEGYCSMYGICEKRSDGKPLNCPSNTPSVKPDKLLSSKVQSLCPTITGNVCCTADQFDTL 519
            +E YC+MY IC +RSDGK LNCP  +PSVKPD LLS+K+QSLCPTITGNVCCTADQFDTL
Sbjct: 33   SEEYCAMYDICGQRSDGKALNCPYGSPSVKPDDLLSAKIQSLCPTITGNVCCTADQFDTL 92

Query: 520  RGQVQQAIPFLVGCPACLRNFLNVFCELSCSPNQSLFINVTSVMKGSNTTTVDGIDLYIT 699
            R QVQQA+P LVGCPACLRNFLN+FCELSCSPNQSLFINVTS+ +    TTVDGID ++T
Sbjct: 93   RVQVQQAVPILVGCPACLRNFLNLFCELSCSPNQSLFINVTSISEVDGNTTVDGIDYHLT 152

Query: 700  STYGEALYNSCKDVKFGTMNTRAMDFIGGGAQNYNEWFAFIGKQAGVGEIGSPYAIDFRS 879
             T+G+ LY SCKDVKFGTMNTRA+DF+G GA N+ EW  F+G++   G  GSPY+I F++
Sbjct: 153  ETFGQGLYESCKDVKFGTMNTRAIDFVGAGASNFKEWAEFLGQKVPPGFPGSPYSILFKT 212

Query: 880  NISDSSGMKPMNVTVHSCGDLSLGCSCGDCPSSSVCSESATPASHKQGSCHVKMGSLEVN 1059
             I DSS MK MN +V+SC D SLGCSCGDCPSS VCS S  P+  ++  C + +GSL+V 
Sbjct: 213  AILDSSPMKLMNASVYSCNDTSLGCSCGDCPSSPVCSGSE-PSPPRKDPCSIGIGSLKVR 271

Query: 1060 CLEFSLAVVYIVFISVLLLWGLLHRKRVKEGPSSKTNPLVN--VKDENEPVNKQETSIQP 1233
            C++FS+A++YIV + VL  W LL R R +    S   PL++  V + +   N  +    P
Sbjct: 272  CVDFSIAILYIVLVFVLFGWALLQRTRGRRRLGSSAEPLLDDMVGEGSSFANLPKDGTHP 331

Query: 1234 VQI----PEGPPAVQALQPSIVQRYMSSFFRKYGAFVSRKPLLILCLSVAVPLLLCIGLV 1401
             ++    P+G   VQ    S VQ  +SSF+R YG + +RKP ++LC S+A+ +LLC+GL+
Sbjct: 332  AEVQWIDPQGQNVVQF---SFVQGCLSSFYRTYGRWAARKPTIVLCSSLAIVVLLCLGLL 388

Query: 1402 RFKVETRPEKLWVGPGSKAAEEKKYFDYHLAPFYRIEELILATVPGSKDGKSPSIVSDEN 1581
            RF+VETRPEKLWVGPGSKAAEEK++FD HLAPFYRIE+LI+AT+P SK GK PSI+++EN
Sbjct: 389  RFEVETRPEKLWVGPGSKAAEEKEFFDSHLAPFYRIEQLIIATIPESKHGKPPSIITEEN 448

Query: 1582 MKLLFEIQKKIDGLKVNYSGSMISLSDICLKPLGDACATQSVLQYFKMDPENYNNYGGVE 1761
            ++LLFEIQ+K+DG++ NYSG ++SLSDICLKPLGD CATQS+LQYF+MDP+NY+NYGGVE
Sbjct: 449  IELLFEIQEKVDGIRANYSGFLVSLSDICLKPLGDDCATQSILQYFQMDPDNYDNYGGVE 508

Query: 1762 HADYCFLHYSSAETCLSAFQAPLDPSTALGGFSGNNFSEASAFVITYPVNNEVERTGNEN 1941
            HA+YCF HY+S ETC SAF+APL+P+TALGGFSGNN+SEASAFVITYPVNN + + G EN
Sbjct: 509  HAEYCFQHYTSTETCFSAFKAPLEPTTALGGFSGNNYSEASAFVITYPVNNAITKVGGEN 568

Query: 1942 GKAVAWEKAFVRLVKEEIGPMVKLQNLTLSFSSESSVQEELKRESSADVITILVSYLVMF 2121
            GKA+AWEKAF++L K+E+ PMV+  NLTLSFS+ESS++EELKRES+ADVITILVSY+VMF
Sbjct: 569  GKAIAWEKAFIQLAKDELLPMVQSSNLTLSFSTESSIEEELKRESTADVITILVSYIVMF 628

Query: 2122 AYISFTLGDSPHXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXAIGVKSTLIIMEVIP 2301
            AYIS TLGD+P                                  AIGVKSTLIIMEVIP
Sbjct: 629  AYISVTLGDTPPHPSFFFLSSKVLLGLLGVLLVMLSVLGSVGFFSAIGVKSTLIIMEVIP 688

Query: 2302 FLVLAVGVDNMCILVHAFKRQPLDLPLEGRVSNALVEVGPSITLASLSEVLAFAVGSFIP 2481
            FLVLAVGVDNMCI+V A KRQP  LP+E ++SNA+ EVGPSITLASLSE+LAFAVGSF+ 
Sbjct: 689  FLVLAVGVDNMCIIVDAVKRQPSGLPVEEQISNAMGEVGPSITLASLSEILAFAVGSFVS 748

Query: 2482 MPACRVFSMXXXXXXXXXXXXQVTAFVALIVLDFLRAEDYRIDCIPCVKVSL-SDESNKG 2658
            MPACRVFSM            Q+TAFVAL+ LDF+RA+D RIDC PCVK++  S E N+G
Sbjct: 749  MPACRVFSMIAALAVLLDFLLQITAFVALVTLDFMRAKDNRIDCFPCVKLNPPSAEQNEG 808

Query: 2659 DDPRNLGLVARYMKDVHAPMLEIPGVKMIVIAVFVAFSFASIDLCTRLQPGLEQQVVLPR 2838
                  GL+ RYMK+VHAP L + GVK++VIAVF AF+ ASI LCTR++ GLEQQ+ LPR
Sbjct: 809  IRLERDGLLTRYMKEVHAPFLGLWGVKILVIAVFAAFTLASIALCTRIEAGLEQQIALPR 868

Query: 2839 DSYLQDYFGDLAKYLRVGPPLYFVVKDFNYSLESEQTNQLCSISQCDSNSLLNEITRASL 3018
            DSYLQ YF ++++YLRVGPPLYFVVKD+NYSLES+ TNQLCSIS CDSNSLLNEI+RASL
Sbjct: 869  DSYLQGYFSNISEYLRVGPPLYFVVKDYNYSLESKHTNQLCSISHCDSNSLLNEISRASL 928

Query: 3019 TAESSYIAKPAASWLDDFLIWLSPEAFSCCRKFVNGSYXXXXXXXXXXXXGDSSCGMGGI 3198
               SSYIAKPAASWLDDFL+W+SPEAFSCCRKF N SY             +  CG+GG+
Sbjct: 929  VPTSSYIAKPAASWLDDFLVWISPEAFSCCRKFTNDSYCPPDDQPPCCLPDEGPCGLGGV 988

Query: 3199 CKDCTTCFRHSDLQDGRPSTSQFKEKLPWFLKALPSSNCAKGGNGAYTSSVDLTGYDSGI 3378
            CKDCTTCFRHSDL + RPST+QF+EKLPWFL ALPS++CAKGG+GAYT+SVDL GY+ G+
Sbjct: 989  CKDCTTCFRHSDLVNDRPSTAQFREKLPWFLDALPSADCAKGGHGAYTNSVDLNGYEGGV 1048

Query: 3379 IQASSFRTYHTPLNKQSDYVNGMRAAREFSSEVSKSLKMQIFPYSVFYIFFEQYLDIWKT 3558
            IQAS FRTYHTPLN+Q DYVN +RAAR+FS+ +S SLKM IFPYSVFYIFFEQYLDIWK 
Sbjct: 1049 IQASEFRTYHTPLNRQGDYVNAIRAARDFSAIISSSLKMDIFPYSVFYIFFEQYLDIWKL 1108

Query: 3559 ALVNILIGLGAVFIVCSVITCSFWTSTIILVVLAMIVIDMMGVMAILKIQLNAISVVNLV 3738
            AL+NI + LGA+F+VC +IT S W+S I+L+VL MI++D+MGVMAIL IQLNA+SVVNL+
Sbjct: 1109 ALINITVALGAIFVVCLIITSSVWSSAILLLVLIMIILDLMGVMAILGIQLNAVSVVNLI 1168

Query: 3739 MSIGIAVEFCVHITHSFSVSCGDRGTRARAALCTMGASIFSGITLTKLVGVIVLRFARSE 3918
            MSIGIAVEFCVHI H+F VS GDR  RA+ ALCTMGAS+FSGITLTKLVGV+VL F+ SE
Sbjct: 1169 MSIGIAVEFCVHIVHAFMVSLGDRSQRAKTALCTMGASVFSGITLTKLVGVLVLCFSTSE 1228

Query: 3919 IFVVYYFQMYLALVLLGFLH 3978
            IFVVYYFQMYLALV++GFLH
Sbjct: 1229 IFVVYYFQMYLALVIIGFLH 1248


>gb|PAN39594.1| hypothetical protein PAHAL_G01943 [Panicum hallii]
          Length = 1291

 Score = 1657 bits (4292), Expect = 0.0
 Identities = 827/1247 (66%), Positives = 980/1247 (78%), Gaps = 3/1247 (0%)
 Frame = +1

Query: 247  IQVNLHVFSASAQDSHSHFRILAGARPEKISAEGYCSMYGICEKRSDGKPLNCPSNTPSV 426
            +Q++  VF  SAQ+S+S            + AEGYCSMYGIC +RSDGK LNC + T +V
Sbjct: 21   MQISFLVFPISAQESNSS---------RVVPAEGYCSMYGICGQRSDGKVLNCANATKAV 71

Query: 427  KPDKLLSSKVQSLCPTITGNVCCTADQFDTLRGQVQQAIPFLVGCPACLRNFLNVFCELS 606
            KPD L SS+VQSLCPTITGNVCCT DQFDTL  QVQQA+PFLVGCPACLRNFLN+FCE+S
Sbjct: 72   KPDTLFSSRVQSLCPTITGNVCCTVDQFDTLHQQVQQAVPFLVGCPACLRNFLNLFCEMS 131

Query: 607  CSPNQSLFINVTSVMKGSNTTTVDGIDLYITSTYGEALYNSCKDVKFGTMNTRAMDFIGG 786
            CSPNQSLFINVTSV + ++T TVDGID Y+T+ YGE LYNSCKDVKFGT+NTRAMDF+GG
Sbjct: 132  CSPNQSLFINVTSVKQINSTATVDGIDYYVTTNYGEDLYNSCKDVKFGTLNTRAMDFLGG 191

Query: 787  GAQNYNEWFAFIGKQAGVGEIGSPYAIDFRSNISDSSGMKPMNVTVHSCGDLSLGCSCGD 966
            GA+ Y EW AF+G+QA   E GSPY I +RS+ SDSSG+KP+N T++SCGD SLGCSCGD
Sbjct: 192  GAKTYKEWLAFLGRQAKPNEPGSPYLITYRSDSSDSSGVKPLNSTIYSCGDPSLGCSCGD 251

Query: 967  CPSSSVCSESATPASHKQGSCHVKMGSLEVNCLEFSLAVVYIVFISVLLLWGLLHRKRVK 1146
            CPSSSVC+ S  P  + + SC VKMGSL+  CL+FSL VVY+  +  +LLWGLL+R R +
Sbjct: 252  CPSSSVCTGSLLPQLNTETSCSVKMGSLKAKCLDFSLVVVYLALLCAVLLWGLLYRTRGR 311

Query: 1147 EGPSSKTNPLVNVKDENEPVNKQETSIQPVQIPEGPPA-VQALQPSIVQRYMSSFFRKYG 1323
                 KT PL N  D+++     ++    VQ+ E   + V+   PSIVQ YMS FFRK+G
Sbjct: 312  TAFPLKTKPLRNSDDKSDSNKNGKSPHNSVQVSEAASSTVKPSHPSIVQTYMSIFFRKHG 371

Query: 1324 AFVSRKPLLILCLSVAVPLLLCIGLVRFKVETRPEKLWVGPGSKAAEEKKYFDYHLAPFY 1503
             FV+R PLL+LC+S+ +P+LLCIGL+RFKVETRPEKLWV PGS+ A EK YFD HL PFY
Sbjct: 372  IFVARHPLLVLCVSLLIPVLLCIGLLRFKVETRPEKLWVSPGSRTAGEKNYFDSHLTPFY 431

Query: 1504 RIEELILATVPGSKDGKSPSIVSDENMKLLFEIQKKIDGLKVNYSGSMISLSDICLKPLG 1683
            RIE+L+LAT   S    +PSIV+D NMKLLF+IQKK+D L+ NYSGS ++L+DICLKPL 
Sbjct: 432  RIEQLVLAT-SASGGSAAPSIVNDNNMKLLFQIQKKVDDLRANYSGSTVALADICLKPLS 490

Query: 1684 DACATQSVLQYFKMDPENYNNYGGVEHADYCFLHYSSAETCLSAFQAPLDPSTALGGFSG 1863
              CATQSVLQYF++DP+ Y++  G++HA +CF HY+S ETCLS FQ+P+DPST LGGF G
Sbjct: 491  TDCATQSVLQYFQLDPKKYDD-SGIDHAKFCFQHYTSEETCLSTFQSPIDPSTILGGFPG 549

Query: 1864 NNFSEASAFVITYPVNNEVERTGNENGKAVAWEKAFVRLVKEEIGPMVKLQNLTLSFSSE 2043
            NNF+EASAFVITYPVNN+VE TG ENGKAVAWE+AF+ LVKEEI PMV  QNLTLSFSSE
Sbjct: 550  NNFTEASAFVITYPVNNKVETTGQENGKAVAWERAFISLVKEEILPMVLAQNLTLSFSSE 609

Query: 2044 SSVQEELKRESSADVITILVSYLVMFAYISFTLGDSPHXXXXXXXXXXXXXXXXXXXXXX 2223
            SS+Q+EL RES+AD ITI++SY+VMFAYISFTLGD P                       
Sbjct: 610  SSIQDELNRESTADAITIVISYIVMFAYISFTLGDRPSRWLSLFVSSKVLLGLSGVVLVM 669

Query: 2224 XXXXXXXXXXXAIGVKSTLIIMEVIPFLVLAVGVDNMCILVHAFKRQPLDLPLEGRVSNA 2403
                       AIG+KSTLIIMEVIPFLVLAVGVDNMCILVHA KRQP    LE R+S+A
Sbjct: 670  LSVLGSMGFFSAIGMKSTLIIMEVIPFLVLAVGVDNMCILVHAVKRQPDQSNLEERISDA 729

Query: 2404 LVEVGPSITLASLSEVLAFAVGSFIPMPACRVFSMXXXXXXXXXXXXQVTAFVALIVLDF 2583
            LVEVGPSITLAS +EVLAFAV +  PMPA RVFSM            QVTAFVALIV DF
Sbjct: 730  LVEVGPSITLASFAEVLAFAVSAINPMPATRVFSMFAALAVFMDFILQVTAFVALIVFDF 789

Query: 2584 LRAEDYRIDCIPCVKVSLSDESNKGDDPRNLGLVARYMKDVHAPMLEIPGVKMIVIAVFV 2763
             RA+D RIDC+PC ++  S  +  G D + L L+ARYM+D+H P+L    VK +VIAVFV
Sbjct: 790  RRAQDGRIDCVPCARILSSPTTGDGGDGQKLHLLARYMRDIHGPILSYRAVKFVVIAVFV 849

Query: 2764 AFSFASIDLCTRLQPGLEQQVVLPRDSYLQDYFGDLAKYLRVGPPLYFVVKDFNYSLESE 2943
              +FASI L TRLQPGLEQ++VLPR+SYLQ YF DLAKY++VGPPLYFVVK+FNYS  S 
Sbjct: 850  GLAFASIALSTRLQPGLEQKIVLPRNSYLQGYFDDLAKYMKVGPPLYFVVKNFNYSSASV 909

Query: 2944 QTNQLCSISQCDSNSLLNEITRASLTAESSYIAKPAASWLDDFLIWLSPEAFSCCRKFVN 3123
             TNQ+CSI+QC+SNSLLNEI R SL+ E+SYIAKPAASWLDDFLIW+SPEAF CCRKFVN
Sbjct: 910  HTNQICSINQCNSNSLLNEIARQSLSPETSYIAKPAASWLDDFLIWMSPEAFGCCRKFVN 969

Query: 3124 GSYXXXXXXXXXXXXGDSS--CGMGGICKDCTTCFRHSDLQDGRPSTSQFKEKLPWFLKA 3297
            GSY               S  C     C +CTTCF HS+L +GRPST+QFK+KLPWFL A
Sbjct: 970  GSYCPPDDQPPCCQLDQDSGTCSASATCNNCTTCFLHSELDNGRPSTTQFKDKLPWFLDA 1029

Query: 3298 LPSSNCAKGGNGAYTSSVDLTGYDSGIIQASSFRTYHTPLNKQSDYVNGMRAAREFSSEV 3477
            LPSS+C+KGG GAY++S+DL+GY+SGIIQAS+FRTYHTPLNKQ+DYVN MRAAR+FSS++
Sbjct: 1030 LPSSDCSKGGKGAYSTSLDLSGYESGIIQASAFRTYHTPLNKQTDYVNSMRAARDFSSKM 1089

Query: 3478 SKSLKMQIFPYSVFYIFFEQYLDIWKTALVNILIGLGAVFIVCSVITCSFWTSTIILVVL 3657
            S+ L+M+IFPYSVFYIFFEQYL +WKTA++NI + LG VF+VC ++T S W S IIL+VL
Sbjct: 1090 SEDLQMEIFPYSVFYIFFEQYLGVWKTAIMNICVCLGTVFVVCFIVTSSLWASAIILIVL 1149

Query: 3658 AMIVIDMMGVMAILKIQLNAISVVNLVMSIGIAVEFCVHITHSFSVSCGDRGTRARAALC 3837
            AMIV+D+MGVMA+L IQLNAISVVNLVMSIGIAVEFCVHITH+F +  GDR TRAR AL 
Sbjct: 1150 AMIVLDLMGVMAMLGIQLNAISVVNLVMSIGIAVEFCVHITHAFMIGNGDRETRARQALS 1209

Query: 3838 TMGASIFSGITLTKLVGVIVLRFARSEIFVVYYFQMYLALVLLGFLH 3978
            TMGAS+FSGITLTKLVGVIVLRFA+SE+FVVYYFQMYLALVL+GFLH
Sbjct: 1210 TMGASVFSGITLTKLVGVIVLRFAKSEVFVVYYFQMYLALVLIGFLH 1256


>ref|XP_004491642.1| PREDICTED: Niemann-Pick C1 protein [Cicer arietinum]
          Length = 1278

 Score = 1657 bits (4290), Expect = 0.0
 Identities = 807/1218 (66%), Positives = 973/1218 (79%), Gaps = 3/1218 (0%)
 Frame = +1

Query: 334  ISAEGYCSMYGICEKRSDGKPLNCPSNTPSVKPDKLLSSKVQSLCPTITGNVCCTADQFD 513
            I ++ YC+MY IC +R+DGK LNCP ++PSVKPD LLS+K+QSLCP+I GNVCCT  QFD
Sbjct: 40   IHSDEYCAMYDICGQRTDGKVLNCPYSSPSVKPDDLLSAKIQSLCPSINGNVCCTEQQFD 99

Query: 514  TLRGQVQQAIPFLVGCPACLRNFLNVFCELSCSPNQSLFINVTSVMKGSNTTTVDGIDLY 693
            TLR QVQQA+P LVGCPACLRNFLN+FCELSCSP+QSLFINVTSV + +   TVDGID Y
Sbjct: 100  TLRVQVQQAVPILVGCPACLRNFLNLFCELSCSPSQSLFINVTSVSQVNGNMTVDGIDFY 159

Query: 694  ITSTYGEALYNSCKDVKFGTMNTRAMDFIGGGAQNYNEWFAFIGKQAGVGEIGSPYAIDF 873
            +T T+GE LY SCKDVKFGTMNTRAMDF+G GA NY EW AF+G++   G  GSPY+I F
Sbjct: 160  VTETFGEGLYQSCKDVKFGTMNTRAMDFVGAGASNYEEWLAFLGEKVPPGFPGSPYSIHF 219

Query: 874  RSNISDSSGMKPMNVTVHSCGDLSLGCSCGDCPSSSVCSESATPASHKQGSCHVKMGSLE 1053
            ++ I DSS M+PMN +V++C D SLGCSCGDCPSS VCS S  P   K   C +++GSL+
Sbjct: 220  KTTIPDSSPMEPMNASVYTCNDTSLGCSCGDCPSSPVCSGSEPPPP-KSDPCSIRLGSLK 278

Query: 1054 VNCLEFSLAVVYIVFISVLLLWGLLHRKRVKEGPSSKTNPLVNVKDENEPVNKQETSIQP 1233
            V C++FSLA++YI+ + VL  W LL R R +    S   PL+N  + +   N Q     P
Sbjct: 279  VRCVDFSLALLYILLVFVLFGWVLLKRTRQERSLGSNVEPLLNDGEGSSFTNIQREGTHP 338

Query: 1234 --VQIPEGPPAVQALQPSIVQRYMSSFFRKYGAFVSRKPLLILCLSVAVPLLLCIGLVRF 1407
              VQ+ E      A+Q S V   +S F+R YG + +R+P +IL  S+A+ LLLC+GL+RF
Sbjct: 339  EEVQVME-QKRQNAMQYSFVHGCLSRFYRAYGRWAARRPAIILFSSLAIVLLLCLGLLRF 397

Query: 1408 KVETRPEKLWVGPGSKAAEEKKYFDYHLAPFYRIEELILATVPGSKDGKSPSIVSDENMK 1587
            +VETRPEKLWVGPGSKAAEEK +FD HLAPFYRIE+LI+ATVP SK GK PSI++++N++
Sbjct: 398  QVETRPEKLWVGPGSKAAEEKDFFDSHLAPFYRIEQLIIATVPESKHGKPPSIITEDNIE 457

Query: 1588 LLFEIQKKIDGLKVNYSGSMISLSDICLKPLGDACATQSVLQYFKMDPENYNNYGGVEHA 1767
            LLFEIQ+K+D ++ NYSG +ISLSDICL+PLGD CATQS+LQYF+MDP+NY+NYGGVEHA
Sbjct: 458  LLFEIQEKVDAIRANYSGLLISLSDICLRPLGDDCATQSILQYFQMDPDNYDNYGGVEHA 517

Query: 1768 DYCFLHYSSAETCLSAFQAPLDPSTALGGFSGNNFSEASAFVITYPVNNEVERTGNENGK 1947
            +YCF HY+S ETC SAF+APL+P+TALGGFSGNN+SEASAF+ITYPVNN + + G+ENGK
Sbjct: 518  EYCFQHYTSTETCFSAFKAPLEPTTALGGFSGNNYSEASAFIITYPVNNAITKVGDENGK 577

Query: 1948 AVAWEKAFVRLVKEEIGPMVKLQNLTLSFSSESSVQEELKRESSADVITILVSYLVMFAY 2127
            A+AWE+AF+RL KEE+ PMV+  NLTLSFS+ESS++EELKRES+ADVITILVSY+VMFAY
Sbjct: 578  AIAWEEAFIRLAKEELLPMVQSSNLTLSFSAESSIEEELKRESTADVITILVSYVVMFAY 637

Query: 2128 ISFTLGDSPHXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXAIGVKSTLIIMEVIPFL 2307
            IS TLGD+P                                  A+GVKSTLIIMEVIPFL
Sbjct: 638  ISVTLGDTPPRLSSFYLSTKVLLGLSGVLLVLLSVLGSVGFFSAVGVKSTLIIMEVIPFL 697

Query: 2308 VLAVGVDNMCILVHAFKRQPLDLPLEGRVSNALVEVGPSITLASLSEVLAFAVGSFIPMP 2487
            VLAVGVDNMCI++ A KRQP DLP+E ++SNA+ EVGPSITLASLSE+LAFAVGSF+ MP
Sbjct: 698  VLAVGVDNMCIIIDAVKRQPSDLPIEEQISNAMGEVGPSITLASLSEILAFAVGSFVSMP 757

Query: 2488 ACRVFSMXXXXXXXXXXXXQVTAFVALIVLDFLRAEDYRIDCIPCVKVS-LSDESNKGDD 2664
            ACRVFSM            Q+TAFVAL+ LDF+RA+D R+DC PC+K++  S E  +G  
Sbjct: 758  ACRVFSMIAALAVLLDFLLQITAFVALVTLDFVRAKDNRVDCFPCIKLNRYSMEQTEGIR 817

Query: 2665 PRNLGLVARYMKDVHAPMLEIPGVKMIVIAVFVAFSFASIDLCTRLQPGLEQQVVLPRDS 2844
                GL+ RYMK+VHAP L + GVK++VIA+F AF+ ASI LCTR++PGLEQQ+ LPRDS
Sbjct: 818  QETDGLLTRYMKEVHAPFLGLWGVKVLVIAIFGAFTLASIALCTRIEPGLEQQIALPRDS 877

Query: 2845 YLQDYFGDLAKYLRVGPPLYFVVKDFNYSLESEQTNQLCSISQCDSNSLLNEITRASLTA 3024
            YLQ YF ++++YLRVGPPLYFVVKD+NYSLES+ TNQLCSIS CDSNSLLNEI+RASL  
Sbjct: 878  YLQGYFSNISEYLRVGPPLYFVVKDYNYSLESKHTNQLCSISHCDSNSLLNEISRASLVP 937

Query: 3025 ESSYIAKPAASWLDDFLIWLSPEAFSCCRKFVNGSYXXXXXXXXXXXXGDSSCGMGGICK 3204
            +SSYIAKPAASWLDDFL+W+SPEAFSCCRKF+N SY             +  CG+GG+CK
Sbjct: 938  KSSYIAKPAASWLDDFLVWISPEAFSCCRKFINDSYCPPDDQPPCCLPDEGPCGLGGVCK 997

Query: 3205 DCTTCFRHSDLQDGRPSTSQFKEKLPWFLKALPSSNCAKGGNGAYTSSVDLTGYDSGIIQ 3384
            DCTTCFRHSDL + RPST+QFKEKLPWFL ALPS++CAKGG+GAYT+S+DL GY  G+IQ
Sbjct: 998  DCTTCFRHSDLVNDRPSTAQFKEKLPWFLDALPSADCAKGGHGAYTNSIDLNGYGHGVIQ 1057

Query: 3385 ASSFRTYHTPLNKQSDYVNGMRAAREFSSEVSKSLKMQIFPYSVFYIFFEQYLDIWKTAL 3564
            AS FRTYHTPLN+Q DYVN +RAAREF S +S SLKM IFPYSVFYIFFEQYLD+W  AL
Sbjct: 1058 ASEFRTYHTPLNRQGDYVNAIRAAREFCSRISASLKMDIFPYSVFYIFFEQYLDVWNIAL 1117

Query: 3565 VNILIGLGAVFIVCSVITCSFWTSTIILVVLAMIVIDMMGVMAILKIQLNAISVVNLVMS 3744
            +NI I LGAVF+VC VIT S W+S IIL+VL MI++D+MGVMAIL IQLNA+S+VNL+M+
Sbjct: 1118 INIAIALGAVFVVCLVITSSLWSSAIILLVLLMIILDLMGVMAILGIQLNAVSIVNLIMA 1177

Query: 3745 IGIAVEFCVHITHSFSVSCGDRGTRARAALCTMGASIFSGITLTKLVGVIVLRFARSEIF 3924
            IGIAVEFCVHI H+F VS GDR  RAR ALCTMGAS+FSGITLTKLVGV+VL F+ SEIF
Sbjct: 1178 IGIAVEFCVHIAHAFMVSSGDRSQRARTALCTMGASVFSGITLTKLVGVLVLYFSTSEIF 1237

Query: 3925 VVYYFQMYLALVLLGFLH 3978
            VVYYFQMYLALV++GFLH
Sbjct: 1238 VVYYFQMYLALVIIGFLH 1255


>ref|XP_007142570.1| hypothetical protein PHAVU_008G291900g [Phaseolus vulgaris]
 gb|ESW14564.1| hypothetical protein PHAVU_008G291900g [Phaseolus vulgaris]
          Length = 1288

 Score = 1656 bits (4288), Expect = 0.0
 Identities = 807/1239 (65%), Positives = 987/1239 (79%), Gaps = 3/1239 (0%)
 Frame = +1

Query: 271  SASAQDSHSHFRILAGARPEKISAEGYCSMYGICEKRSDGKPLNCPSNTPSVKPDKLLSS 450
            S SA   H  +R           +E YC+MYGIC +RSDGK LNCP  +PSVKPD+LLS+
Sbjct: 20   SLSAASQHETYRAK--------HSEEYCAMYGICAQRSDGKALNCPYGSPSVKPDELLSA 71

Query: 451  KVQSLCPTITGNVCCTADQFDTLRGQVQQAIPFLVGCPACLRNFLNVFCELSCSPNQSLF 630
            K+QSLCP+ITGNVCCTADQFDTLR QVQQA+P LVGCP+CLRNFLN+FCELSCSPNQSLF
Sbjct: 72   KIQSLCPSITGNVCCTADQFDTLRVQVQQAMPILVGCPSCLRNFLNLFCELSCSPNQSLF 131

Query: 631  INVTSVMKGSNTTTVDGIDLYITSTYGEALYNSCKDVKFGTMNTRAMDFIGGGAQNYNEW 810
            INVTS+ + +   TVDGID Y+T T+GE LY SCKDVKFGTMNTRA+DF+G GA N+ EW
Sbjct: 132  INVTSISEVNGNMTVDGIDFYVTETFGEGLYESCKDVKFGTMNTRAIDFVGAGASNFKEW 191

Query: 811  FAFIGKQAGVGEIGSPYAIDFRSNISDSSGMKPMNVTVHSCGDLSLGCSCGDCPSSSVCS 990
            F F+G++   G  GSPY+I F++   D S MK MN +V+SC D SLGCSCGDCPSSSVCS
Sbjct: 192  FEFLGQKVPPGLPGSPYSILFKTATLDPSPMKLMNASVYSCNDTSLGCSCGDCPSSSVCS 251

Query: 991  ESATPASHKQGSCHVKMGSLEVNCLEFSLAVVYIVFISVLLLWGLLHRKRVKEGPSSKTN 1170
             +  P+   +  C +++ SL+V C++FSLA++YIV + VL  W L    R +  P S   
Sbjct: 252  -APEPSPPSKDPCAIRIWSLKVRCVDFSLAILYIVLVFVLFGWALQQGSRGRRRPESSVE 310

Query: 1171 PLVN--VKDENEPVNKQETSIQPVQIPEGPPAVQ-ALQPSIVQRYMSSFFRKYGAFVSRK 1341
            PL+N  V + +   + Q+    PV++ +  P  Q  +Q S VQ ++SSF+R YG + +R 
Sbjct: 311  PLLNDMVGEGSSLADLQKDGNHPVEVQQLDPQGQNVVQFSFVQGWLSSFYRTYGRWAARN 370

Query: 1342 PLLILCLSVAVPLLLCIGLVRFKVETRPEKLWVGPGSKAAEEKKYFDYHLAPFYRIEELI 1521
            P ++LC S+A+ +LLC+GL+RF+VETRPEKLWVGPGSKAAEEK +FD  LAPFYRIE+LI
Sbjct: 371  PTIVLCSSLAIVVLLCLGLLRFEVETRPEKLWVGPGSKAAEEKDFFDNQLAPFYRIEQLI 430

Query: 1522 LATVPGSKDGKSPSIVSDENMKLLFEIQKKIDGLKVNYSGSMISLSDICLKPLGDACATQ 1701
            +AT+P SK GK PSI+++EN++LLFEIQ+K+DG++ NYSG ++SLSDICLKPLG+ CATQ
Sbjct: 431  IATIPESKHGKPPSIITEENIQLLFEIQEKVDGIRANYSGLLVSLSDICLKPLGEDCATQ 490

Query: 1702 SVLQYFKMDPENYNNYGGVEHADYCFLHYSSAETCLSAFQAPLDPSTALGGFSGNNFSEA 1881
            S+LQYF+MDP+NY+NYGGVEHA+YCF HY+S ETC SAF+APL+P+TALGGFSGNN+SEA
Sbjct: 491  SILQYFQMDPDNYDNYGGVEHAEYCFEHYTSTETCFSAFKAPLEPTTALGGFSGNNYSEA 550

Query: 1882 SAFVITYPVNNEVERTGNENGKAVAWEKAFVRLVKEEIGPMVKLQNLTLSFSSESSVQEE 2061
            SAFVITYPVNN + + G+ENGKA+AWEKAF++L KEE+ PMV+  NLTLSFS+ESS++EE
Sbjct: 551  SAFVITYPVNNAIMKVGDENGKAIAWEKAFIQLAKEELLPMVQTSNLTLSFSTESSIEEE 610

Query: 2062 LKRESSADVITILVSYLVMFAYISFTLGDSPHXXXXXXXXXXXXXXXXXXXXXXXXXXXX 2241
            LKRES+ADVITILVSY+VMFAYIS TLGD+P                             
Sbjct: 611  LKRESTADVITILVSYIVMFAYISVTLGDTPRHPSSFFLSSKVLLGLLGVLLVMLSVLGS 670

Query: 2242 XXXXXAIGVKSTLIIMEVIPFLVLAVGVDNMCILVHAFKRQPLDLPLEGRVSNALVEVGP 2421
                 AIGVKSTLIIMEVIPFLVLAVGVDNMCI+V A KRQP +L +E ++SNA+ EVGP
Sbjct: 671  VGFFSAIGVKSTLIIMEVIPFLVLAVGVDNMCIIVDAVKRQPSNLSVEEKISNAMGEVGP 730

Query: 2422 SITLASLSEVLAFAVGSFIPMPACRVFSMXXXXXXXXXXXXQVTAFVALIVLDFLRAEDY 2601
            SITLAS+SE+LAFAVGSF+ MPACRVFSM            Q+TAFVAL+ LDF+RA+D 
Sbjct: 731  SITLASVSEILAFAVGSFVSMPACRVFSMIAALAVLLDFLLQITAFVALVTLDFVRAKDN 790

Query: 2602 RIDCIPCVKVSLSDESNKGDDPRNLGLVARYMKDVHAPMLEIPGVKMIVIAVFVAFSFAS 2781
            RIDC PC+K++ S E N+G+     GL+ +YMK+VHAP L +  VK++VIA+FV F+ AS
Sbjct: 791  RIDCFPCIKLNRSSE-NEGNRQEKDGLLTQYMKEVHAPFLGLRVVKILVIAIFVGFTLAS 849

Query: 2782 IDLCTRLQPGLEQQVVLPRDSYLQDYFGDLAKYLRVGPPLYFVVKDFNYSLESEQTNQLC 2961
            I LCTR++PGLEQQ+ LPRDSYLQ YF ++++YLRVGPPLYFVVKD+NYSLES+ TNQLC
Sbjct: 850  IALCTRIEPGLEQQIALPRDSYLQGYFSNISEYLRVGPPLYFVVKDYNYSLESKHTNQLC 909

Query: 2962 SISQCDSNSLLNEITRASLTAESSYIAKPAASWLDDFLIWLSPEAFSCCRKFVNGSYXXX 3141
            SIS CDSNSLLNEI+RASL  +SSYIAKPAASWLDDFL+W+SPEAFSCCRKF NGSY   
Sbjct: 910  SISHCDSNSLLNEISRASLVPKSSYIAKPAASWLDDFLVWMSPEAFSCCRKFTNGSYCPP 969

Query: 3142 XXXXXXXXXGDSSCGMGGICKDCTTCFRHSDLQDGRPSTSQFKEKLPWFLKALPSSNCAK 3321
                      +  CG+GG+C+DCTTCF HSDL + RPS +QF+EKLPWFL ALPS++CAK
Sbjct: 970  DDQPPCCLPDEGPCGLGGVCQDCTTCFLHSDLVNDRPSAAQFREKLPWFLDALPSADCAK 1029

Query: 3322 GGNGAYTSSVDLTGYDSGIIQASSFRTYHTPLNKQSDYVNGMRAAREFSSEVSKSLKMQI 3501
            GG+GAYT+SVDL GY+SG+IQAS FRTYHTPLN Q DYVN ++AAR+FSS +S SLKM I
Sbjct: 1030 GGHGAYTNSVDLNGYESGVIQASEFRTYHTPLNSQGDYVNAIQAARDFSSRISTSLKMDI 1089

Query: 3502 FPYSVFYIFFEQYLDIWKTALVNILIGLGAVFIVCSVITCSFWTSTIILVVLAMIVIDMM 3681
            FPYSVFYIFFEQYLDIWK +L+NI I LGA+F+VC VIT S W+S I+L+VL MI++D+M
Sbjct: 1090 FPYSVFYIFFEQYLDIWKLSLINITIALGAIFVVCLVITSSLWSSAIVLLVLVMIILDLM 1149

Query: 3682 GVMAILKIQLNAISVVNLVMSIGIAVEFCVHITHSFSVSCGDRGTRARAALCTMGASIFS 3861
            GVMAIL IQLNA+SVVNLVMS+GIAVEFCVHI H+F+VS GDR  RA+ ALCT+GAS+FS
Sbjct: 1150 GVMAILGIQLNAVSVVNLVMSLGIAVEFCVHIVHAFTVSLGDRSQRAKTALCTVGASVFS 1209

Query: 3862 GITLTKLVGVIVLRFARSEIFVVYYFQMYLALVLLGFLH 3978
            GITLTKLVGVIVL F+ SE+FVVYYFQMYLALV++GFLH
Sbjct: 1210 GITLTKLVGVIVLCFSTSELFVVYYFQMYLALVIIGFLH 1248


>ref|XP_015636550.1| PREDICTED: Niemann-Pick C1 protein [Oryza sativa Japonica Group]
          Length = 1293

 Score = 1653 bits (4281), Expect = 0.0
 Identities = 822/1218 (67%), Positives = 973/1218 (79%), Gaps = 3/1218 (0%)
 Frame = +1

Query: 334  ISAEGYCSMYGICEKRSDGKPLNCPSNTPSVKPDKLLSSKVQSLCPTITGNVCCTADQFD 513
            + AEGYCSMYGIC +RSDGK LNC + T +VKPD L S+++QSLCPTITG+VCCT DQFD
Sbjct: 47   VPAEGYCSMYGICAQRSDGKVLNCVNATKAVKPDTLFSARIQSLCPTITGDVCCTVDQFD 106

Query: 514  TLRGQVQQAIPFLVGCPACLRNFLNVFCELSCSPNQSLFINVTSVMKGSNTTTVDGIDLY 693
            TL  QVQQAIPFLVGCPACLRNFLN+FCE+SCSPNQSLFINVTSV + +NT TV+GID Y
Sbjct: 107  TLHQQVQQAIPFLVGCPACLRNFLNLFCEMSCSPNQSLFINVTSVKQVNNTMTVNGIDYY 166

Query: 694  ITSTYGEALYNSCKDVKFGTMNTRAMDFIGGGAQNYNEWFAFIGKQAGVGEIGSPYAIDF 873
            +TSTYGE LYNSCKDVKFGT+NTRAMDF+GGGA+NY EW AFIG+QA + +IGSPY I F
Sbjct: 167  VTSTYGEELYNSCKDVKFGTLNTRAMDFLGGGAKNYKEWMAFIGRQADLNQIGSPYLITF 226

Query: 874  RSNISDSSGMKPMNVTVHSCGDLSLGCSCGDCPSSSVCSESATPASHKQGSCHVKMGSLE 1053
             S+IS S+ +KP+N T++SCGD SLGCSCGDCPSSSVC+ S  P  + + SC VKMGSL+
Sbjct: 227  PSDISGSTAVKPLNATIYSCGDPSLGCSCGDCPSSSVCTGSLLPQLNTETSCSVKMGSLK 286

Query: 1054 VNCLEFSLAVVYIVFISVLLLWGLLHRKRVKEGPSSKTNPLVNVKDENEPVNKQETSIQP 1233
              CL+FSL VVY+V + + L    LHR R + G  S T PL N +D+    N  +     
Sbjct: 287  AKCLDFSLVVVYLVLLCIFLFGAFLHRTR-RSGIFSHTKPLKNAEDKIHSSNNGKVPDSS 345

Query: 1234 VQIPEGPPA-VQALQPSIVQRYMSSFFRKYGAFVSRKPLLILCLSVAVPLLLCIGLVRFK 1410
             Q+ E   A VQ+  PS++Q YMS+FFRK+G FV++ PLL+L +S+ VP LLCIGL+RFK
Sbjct: 346  AQVSEAASAPVQSAHPSVIQTYMSTFFRKHGTFVAKHPLLVLFVSLLVPTLLCIGLIRFK 405

Query: 1411 VETRPEKLWVGPGSKAAEEKKYFDYHLAPFYRIEELILATVPGSKDGKSPSIVSDENMKL 1590
            VE RPEKLWV  GS+AA+EK+YFD HLAPFYRIE+L+LAT       ++P+IV+D NMKL
Sbjct: 406  VEIRPEKLWVSSGSRAADEKQYFDSHLAPFYRIEQLVLAT-SAFGGSEAPTIVNDNNMKL 464

Query: 1591 LFEIQKKIDGLKVNYSGSMISLSDICLKPLGDACATQSVLQYFKMDPENYNNYGGVEHAD 1770
            LF+IQKKID L+ NYSGS +SL+DICLKPLG  CATQSVLQYF++DP+ Y++  G++HA 
Sbjct: 465  LFQIQKKIDDLRANYSGSTVSLADICLKPLGTECATQSVLQYFQLDPKKYDD-SGIDHAK 523

Query: 1771 YCFLHYSSAETCLSAFQAPLDPSTALGGFSGNNFSEASAFVITYPVNNEVERTGNENGKA 1950
            +CF HY++ ETCLS FQ+P+DPST LGGF GNNF+EASAFVITYPVNN+VE TG ENGKA
Sbjct: 524  FCFQHYTTEETCLSTFQSPIDPSTILGGFPGNNFTEASAFVITYPVNNKVETTGQENGKA 583

Query: 1951 VAWEKAFVRLVKEEIGPMVKLQNLTLSFSSESSVQEELKRESSADVITILVSYLVMFAYI 2130
            VAWE+A+V LVKEEI PMV   NLT+SFSSESS+Q+EL RES+AD ITI++SY+VMFAYI
Sbjct: 584  VAWERAYVNLVKEEILPMVLAHNLTMSFSSESSIQDELNRESTADAITIVISYIVMFAYI 643

Query: 2131 SFTLGDSPHXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXAIGVKSTLIIMEVIPFLV 2310
            SFTLGD P                                  AIGVKSTLIIMEVIPFLV
Sbjct: 644  SFTLGDRPSHLLSLFVSSKVLLGLSGVVLVMLSVLGSMGFFSAIGVKSTLIIMEVIPFLV 703

Query: 2311 LAVGVDNMCILVHAFKRQPLDLPLEGRVSNALVEVGPSITLASLSEVLAFAVGSFIPMPA 2490
            LAVGVDNMCILVHA KRQP  L LE R+S ALVEVGPSITLASL+EVLAFAV +  PMPA
Sbjct: 704  LAVGVDNMCILVHAVKRQPDGLDLEERISTALVEVGPSITLASLAEVLAFAVSAINPMPA 763

Query: 2491 CRVFSMXXXXXXXXXXXXQVTAFVALIVLDFLRAEDYRIDCIPCVKVSLSDESNKGDDPR 2670
             RVFSM            QV+AFVALIVLDF RA+D RIDC+PC +V  S  ++ G + +
Sbjct: 764  TRVFSMFAALAVLLDFLLQVSAFVALIVLDFRRAQDGRIDCMPCARVKSSVVASDGGNHQ 823

Query: 2671 NLGLVARYMKDVHAPMLEIPGVKMIVIAVFVAFSFASIDLCTRLQPGLEQQVVLPRDSYL 2850
             L L+ARYMK+VHAP+L    VK +VIAVFV FSFASI L TRLQPGLEQ++VLPRDSYL
Sbjct: 824  GLPLLARYMKNVHAPILGYRAVKFVVIAVFVGFSFASIALSTRLQPGLEQKIVLPRDSYL 883

Query: 2851 QDYFGDLAKYLRVGPPLYFVVKDFNYSLESEQTNQLCSISQCDSNSLLNEITRASLTAES 3030
            QDYF DLA Y++VGPPLYFV+K+FNYS  SE TN++CSI+QCDSNSLLNEI + SL+ E+
Sbjct: 884  QDYFDDLATYMKVGPPLYFVIKNFNYSSASEHTNKICSINQCDSNSLLNEIAKQSLSPET 943

Query: 3031 SYIAKPAASWLDDFLIWLSPEAFSCCRKFVNGSYXXXXXXXXXXXXGD--SSCGMGGICK 3204
            SYIAKPAASWLDDFLIW+SPEAF CCRKFVNGSY                SSC   G C 
Sbjct: 944  SYIAKPAASWLDDFLIWMSPEAFGCCRKFVNGSYCPPDDQPPCCQHDQDSSSCSASGACN 1003

Query: 3205 DCTTCFRHSDLQDGRPSTSQFKEKLPWFLKALPSSNCAKGGNGAYTSSVDLTGYDSGIIQ 3384
            +CTTCF  SDL +GRPST+QFKEKLPWFL ALPSS+C+KGG GAY++S+DL GY++GIIQ
Sbjct: 1004 NCTTCFLRSDLHNGRPSTTQFKEKLPWFLDALPSSDCSKGGKGAYSTSLDLNGYENGIIQ 1063

Query: 3385 ASSFRTYHTPLNKQSDYVNGMRAAREFSSEVSKSLKMQIFPYSVFYIFFEQYLDIWKTAL 3564
            AS+FRTYHTPLNKQSDYVN M+AAR+FSS++SK L+MQ+FPYSVFYIFFEQYL +WKTA+
Sbjct: 1064 ASAFRTYHTPLNKQSDYVNSMKAARDFSSKMSKELQMQMFPYSVFYIFFEQYLGVWKTAI 1123

Query: 3565 VNILIGLGAVFIVCSVITCSFWTSTIILVVLAMIVIDMMGVMAILKIQLNAISVVNLVMS 3744
            +NI + LG VF+VC V+T S W S IIL+VLAMIV+D+MG+MAIL IQLNAIS+VNLVMS
Sbjct: 1124 MNICVCLGTVFVVCFVVTSSLWASIIILIVLAMIVLDLMGMMAILGIQLNAISIVNLVMS 1183

Query: 3745 IGIAVEFCVHITHSFSVSCGDRGTRARAALCTMGASIFSGITLTKLVGVIVLRFARSEIF 3924
            IGIAVEFCVHITH+F +  G+R +RAR AL TMGAS+FSGITLTKLVGVIVLRFA+SE+F
Sbjct: 1184 IGIAVEFCVHITHAFMIGIGNRESRARQALSTMGASVFSGITLTKLVGVIVLRFAKSEVF 1243

Query: 3925 VVYYFQMYLALVLLGFLH 3978
            VVYYFQMYLALV++GFLH
Sbjct: 1244 VVYYFQMYLALVIIGFLH 1261


>ref|XP_021318590.1| Niemann-Pick C1 protein [Sorghum bicolor]
          Length = 1290

 Score = 1652 bits (4277), Expect = 0.0
 Identities = 821/1247 (65%), Positives = 981/1247 (78%), Gaps = 3/1247 (0%)
 Frame = +1

Query: 247  IQVNLHVFSASAQDSHSHFRILAGARPEKISAEGYCSMYGICEKRSDGKPLNCPSNTPSV 426
            +Q++  +F  SAQ         +G+R   + AEGYCSMYGIC +RSDGK LNC + T +V
Sbjct: 21   MQISSLLFPISAQQ-------FSGSRV--VPAEGYCSMYGICAQRSDGKVLNCANATKAV 71

Query: 427  KPDKLLSSKVQSLCPTITGNVCCTADQFDTLRGQVQQAIPFLVGCPACLRNFLNVFCELS 606
            KPD L SS++QSLCPTITG+VCCT DQFDTL  QVQQA+PFLVGCPACLRNFLN+FCE+S
Sbjct: 72   KPDTLFSSRIQSLCPTITGDVCCTVDQFDTLHQQVQQAVPFLVGCPACLRNFLNLFCEMS 131

Query: 607  CSPNQSLFINVTSVMKGSNTTTVDGIDLYITSTYGEALYNSCKDVKFGTMNTRAMDFIGG 786
            CSPNQSLFINVTSV + ++T TVDG+D Y+T+ YGE LY+SCKDVKFGT+NTRAMDFIG 
Sbjct: 132  CSPNQSLFINVTSVKQINSTMTVDGLDYYVTTNYGEELYDSCKDVKFGTLNTRAMDFIGA 191

Query: 787  GAQNYNEWFAFIGKQAGVGEIGSPYAIDFRSNISDSSGMKPMNVTVHSCGDLSLGCSCGD 966
            GA+ Y +W AFIG+QA   E GSPY I FRS+ SDSSG+KP+N T++SCGD SLGCSCGD
Sbjct: 192  GAKTYKDWLAFIGRQANSNEPGSPYLITFRSDFSDSSGVKPLNSTIYSCGDPSLGCSCGD 251

Query: 967  CPSSSVCSESATPASHKQGSCHVKMGSLEVNCLEFSLAVVYIVFISVLLLWGLLHRKRVK 1146
            CPSSS C+ S  P  + + SC VKMGSL+  CL+FSL V+Y+  +   LLWGLLHR R +
Sbjct: 252  CPSSSECTGSLLPQLNTETSCSVKMGSLKAKCLDFSLVVIYLALLCAFLLWGLLHRTRGR 311

Query: 1147 EGPSSKTNPLVNVKDENEPVNKQETSIQPVQIPEGPPA-VQALQPSIVQRYMSSFFRKYG 1323
                 +T PL N  ++++     ++    VQ+PE   + V+   PSIVQ YMS FFRK+G
Sbjct: 312  TA-FGQTRPLRNSDNKSDSNKNGKSPHNSVQVPEAASSTVKPSNPSIVQAYMSIFFRKHG 370

Query: 1324 AFVSRKPLLILCLSVAVPLLLCIGLVRFKVETRPEKLWVGPGSKAAEEKKYFDYHLAPFY 1503
             FV+R PLL+LC+S+ VP+LLCIGL RFKVETRPEKLWV PGS+AA+EK YFD HLAPFY
Sbjct: 371  IFVARHPLLVLCVSLLVPVLLCIGLFRFKVETRPEKLWVSPGSQAADEKNYFDSHLAPFY 430

Query: 1504 RIEELILATVPGSKDGKSPSIVSDENMKLLFEIQKKIDGLKVNYSGSMISLSDICLKPLG 1683
            RIE+L+LAT   S   ++PSIV+D NMKLLF++QKK+D L+VNYSGS ++L+DICLKPL 
Sbjct: 431  RIEQLVLAT-SASGGSEAPSIVNDNNMKLLFDVQKKVDDLRVNYSGSTVALADICLKPLS 489

Query: 1684 DACATQSVLQYFKMDPENYNNYGGVEHADYCFLHYSSAETCLSAFQAPLDPSTALGGFSG 1863
              CATQSVLQYF++DP+ +++  G++HA +CF HY+S ETCLS FQ+P+DPST LGGF G
Sbjct: 490  TDCATQSVLQYFQLDPKKFDD-SGIDHAKFCFQHYTSEETCLSTFQSPIDPSTILGGFLG 548

Query: 1864 NNFSEASAFVITYPVNNEVERTGNENGKAVAWEKAFVRLVKEEIGPMVKLQNLTLSFSSE 2043
            +NF+EASAFVITYPVNN+VE TG ENGKAVAWE+AF+ LVKEEI PMV  QNLTLSFSSE
Sbjct: 549  SNFTEASAFVITYPVNNKVETTGKENGKAVAWERAFINLVKEEIRPMVLAQNLTLSFSSE 608

Query: 2044 SSVQEELKRESSADVITILVSYLVMFAYISFTLGDSPHXXXXXXXXXXXXXXXXXXXXXX 2223
            SS+Q+EL RES+AD ITI++SY+VMFAYISFTLGD P                       
Sbjct: 609  SSIQDELNRESTADAITIVISYIVMFAYISFTLGDRPSRWLLLFVSSKVLLGLSGVVLVM 668

Query: 2224 XXXXXXXXXXXAIGVKSTLIIMEVIPFLVLAVGVDNMCILVHAFKRQPLDLPLEGRVSNA 2403
                       AIGVKSTLIIMEVIPFLVLAVGVDNMCILVHA KRQP    LE R+SNA
Sbjct: 669  LSVLGSMGFFSAIGVKSTLIIMEVIPFLVLAVGVDNMCILVHAVKRQPDQSNLEERISNA 728

Query: 2404 LVEVGPSITLASLSEVLAFAVGSFIPMPACRVFSMXXXXXXXXXXXXQVTAFVALIVLDF 2583
            LVEVGPSITLAS +EVLAFAV +  P PA RVFSM            QVTAFVALIV DF
Sbjct: 729  LVEVGPSITLASFAEVLAFAVSAINPTPATRVFSMFAALAVFMDFLLQVTAFVALIVFDF 788

Query: 2584 LRAEDYRIDCIPCVKVSLSDESNKGDDPRNLGLVARYMKDVHAPMLEIPGVKMIVIAVFV 2763
             RA+D RIDC+PC ++  S  +  G D + L L+ARYM+D+H P+L    VK +V+ VF+
Sbjct: 789  RRAQDGRIDCVPCARIMPSTGAGDGGDEQRLHLLARYMRDIHGPILSYRAVKFVVVTVFL 848

Query: 2764 AFSFASIDLCTRLQPGLEQQVVLPRDSYLQDYFGDLAKYLRVGPPLYFVVKDFNYSLESE 2943
              +FASI L TRLQPGLEQQ+VLPR+SYLQDYF DLAKY++VGPPLYFVVKDFNYS  S 
Sbjct: 849  GLTFASIALSTRLQPGLEQQIVLPRNSYLQDYFDDLAKYMKVGPPLYFVVKDFNYSSASV 908

Query: 2944 QTNQLCSISQCDSNSLLNEITRASLTAESSYIAKPAASWLDDFLIWLSPEAFSCCRKFVN 3123
             TNQ+CSI+QC+SNSLLNEI+R SL+ E+SYIAKPAASWLDDFL+W+SPEAF CCRKFVN
Sbjct: 909  HTNQICSINQCNSNSLLNEISRQSLSPETSYIAKPAASWLDDFLVWMSPEAFGCCRKFVN 968

Query: 3124 GSYXXXXXXXXXXXXGD--SSCGMGGICKDCTTCFRHSDLQDGRPSTSQFKEKLPWFLKA 3297
            G+Y                 SC     C +CTTCF HSDL +GRPST+QF++KLPWFL A
Sbjct: 969  GNYCPPDDQPPCCQHNQVSGSCVTSSTCSNCTTCFLHSDLDNGRPSTTQFRDKLPWFLDA 1028

Query: 3298 LPSSNCAKGGNGAYTSSVDLTGYDSGIIQASSFRTYHTPLNKQSDYVNGMRAAREFSSEV 3477
            LPSS+C+KGG GAY++S+DL+GY+SGIIQAS+FRTYHTPLNKQSDYVN MRAAR+FSS++
Sbjct: 1029 LPSSDCSKGGKGAYSTSLDLSGYESGIIQASAFRTYHTPLNKQSDYVNSMRAARDFSSKM 1088

Query: 3478 SKSLKMQIFPYSVFYIFFEQYLDIWKTALVNILIGLGAVFIVCSVITCSFWTSTIILVVL 3657
            SK L+M IFPYSVFYIFFEQYL +WKTA++NI + LG +F+VC ++T S W S IIL+VL
Sbjct: 1089 SKDLQMNIFPYSVFYIFFEQYLSVWKTAIMNICVCLGTIFVVCFIVTGSLWASAIILIVL 1148

Query: 3658 AMIVIDMMGVMAILKIQLNAISVVNLVMSIGIAVEFCVHITHSFSVSCGDRGTRARAALC 3837
            AMIV+D+MGVMAIL IQLNAI+VVNLVMSIGIAVEFCVHITH+F +  GDR TRAR AL 
Sbjct: 1149 AMIVLDLMGVMAILGIQLNAIAVVNLVMSIGIAVEFCVHITHAFMIGAGDRETRARQALS 1208

Query: 3838 TMGASIFSGITLTKLVGVIVLRFARSEIFVVYYFQMYLALVLLGFLH 3978
            TMGAS+FSGITLTKLVGVIVLRFA+SE+FVVYYFQMYLALV++GFLH
Sbjct: 1209 TMGASVFSGITLTKLVGVIVLRFAKSEVFVVYYFQMYLALVIIGFLH 1255


>ref|XP_016191044.1| Niemann-Pick C1 protein isoform X1 [Arachis ipaensis]
          Length = 1277

 Score = 1651 bits (4276), Expect = 0.0
 Identities = 806/1216 (66%), Positives = 976/1216 (80%), Gaps = 3/1216 (0%)
 Frame = +1

Query: 340  AEGYCSMYGICEKRSDGKPLNCPSNTPSVKPDKLLSSKVQSLCPTITGNVCCTADQFDTL 519
            +E YC+MY IC + SDGK LNCP  +PSVKPD LLS+K+QSLCPTITGNVCCT  QFDTL
Sbjct: 41   SEEYCAMYDICGESSDGKVLNCPYGSPSVKPDDLLSAKIQSLCPTITGNVCCTEQQFDTL 100

Query: 520  RGQVQQAIPFLVGCPACLRNFLNVFCELSCSPNQSLFINVTSVMKGSNTTTVDGIDLYIT 699
            R QVQQA+P LVGCPACLRNFLN+FCELSCSPNQSLFINVTS+ + +   TVDGID Y+T
Sbjct: 101  RVQVQQAVPILVGCPACLRNFLNLFCELSCSPNQSLFINVTSISEVNGNKTVDGIDFYVT 160

Query: 700  STYGEALYNSCKDVKFGTMNTRAMDFIGGGAQNYNEWFAFIGKQAGVGEIGSPYAIDFRS 879
             T+GE LY+SCKDVKFGTMNTRA+DF+G GA +Y EWFAF+G +   G  GSPY+I+F+ 
Sbjct: 161  ETFGEGLYDSCKDVKFGTMNTRAIDFVGAGANSYKEWFAFLGAKVPPGFPGSPYSINFKI 220

Query: 880  NISDSSGMKPMNVTVHSCGDLSLGCSCGDCPSSSVCSESATPASHKQGSCHVKMGSLEVN 1059
             I DSS M+ MN +V+SC D SLGCSCGDCPSS VCS    P+  ++  C +++GSL+V 
Sbjct: 221  TIPDSSPMELMNASVYSCNDTSLGCSCGDCPSSPVCSHPE-PSPPRKDPCSIRIGSLKVR 279

Query: 1060 CLEFSLAVVYIVFISVLLLWGLLHRKRVKEGPSSKTNPLVN-VKDENEP-VNKQETSIQP 1233
            C+E S+AV+Y+V I +   W LL R+R +        PL+N + DE    ++ Q+    P
Sbjct: 280  CVELSMAVLYVVLIFMFFGWVLLQRRRERRRLGYDAEPLLNDMSDEGSTLISNQKEGTHP 339

Query: 1234 VQIPEGPPAVQALQPSIVQRYMSSFFRKYGAFVSRKPLLILCLSVAVPLLLCIGLVRFKV 1413
             ++          Q S VQ  +S F+R YG +++R+P ++LC SVA+ LLLC+GL+RF+V
Sbjct: 340  EEV----------QFSFVQGCLSRFYRTYGRWIARRPTIVLCSSVAMVLLLCLGLLRFEV 389

Query: 1414 ETRPEKLWVGPGSKAAEEKKYFDYHLAPFYRIEELILATVPGSKDGKSPSIVSDENMKLL 1593
            ETRPEKLWVGPGSKAAEEK++FD HLAPFYRIE+LI+AT+P S+  K PSI++++N++LL
Sbjct: 390  ETRPEKLWVGPGSKAAEEKEFFDSHLAPFYRIEQLIIATIPESEHEKPPSIITEDNIELL 449

Query: 1594 FEIQKKIDGLKVNYSGSMISLSDICLKPLGDACATQSVLQYFKMDPENYNNYGGVEHADY 1773
            FEIQ+K+DG++ NYS S+++LSDICLKPLG+ CATQS+LQYF+MDP+NY+NYGGVEHA+Y
Sbjct: 450  FEIQQKVDGIRANYSTSLVTLSDICLKPLGEDCATQSILQYFQMDPDNYDNYGGVEHAEY 509

Query: 1774 CFLHYSSAETCLSAFQAPLDPSTALGGFSGNNFSEASAFVITYPVNNEVERTGNENGKAV 1953
            CF HY+SAETC SAF+APL+P+TALGGF G+N+SEASAF+ITYPVNN + + G+ENGKA+
Sbjct: 510  CFQHYTSAETCFSAFKAPLEPTTALGGFFGDNYSEASAFIITYPVNNAMTKVGDENGKAI 569

Query: 1954 AWEKAFVRLVKEEIGPMVKLQNLTLSFSSESSVQEELKRESSADVITILVSYLVMFAYIS 2133
            AWEKAF+ L KEE+ PMV+ +NLTLSFS+ESS++EELKRES+ADVITILVSY+VMF YIS
Sbjct: 570  AWEKAFIELAKEELLPMVQSRNLTLSFSTESSIEEELKRESTADVITILVSYIVMFGYIS 629

Query: 2134 FTLGDSPHXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXAIGVKSTLIIMEVIPFLVL 2313
             TLGD+P                                   IGVKSTLIIMEVIPFLVL
Sbjct: 630  VTLGDTPSHQSSFYLSSKVLLGLSGVLLVVLSVLGSVGFFSLIGVKSTLIIMEVIPFLVL 689

Query: 2314 AVGVDNMCILVHAFKRQPLDLPLEGRVSNALVEVGPSITLASLSEVLAFAVGSFIPMPAC 2493
            AVGVDNMCI+V A KRQP DLP+E ++SNA+  VGPSITLASLSE+LAFAVGSFI MPAC
Sbjct: 690  AVGVDNMCIIVDAVKRQPSDLPIEEQISNAMGAVGPSITLASLSEILAFAVGSFISMPAC 749

Query: 2494 RVFSMXXXXXXXXXXXXQVTAFVALIVLDFLRAEDYRIDCIPCVKV-SLSDESNKGDDPR 2670
            RVFSM            Q+TAFVAL+ LDFLRA+D RIDC PC+KV S S E ++G    
Sbjct: 750  RVFSMIAALAVLLDFLLQITAFVALVTLDFLRAKDSRIDCFPCIKVNSSSAEESEGIREE 809

Query: 2671 NLGLVARYMKDVHAPMLEIPGVKMIVIAVFVAFSFASIDLCTRLQPGLEQQVVLPRDSYL 2850
              GL+ RYMK+VHAP L + GVK++VIAVF+AF+ ASI LCTR++PGLEQQ+ LPRDSYL
Sbjct: 810  RGGLLTRYMKEVHAPFLGLWGVKILVIAVFIAFTLASIALCTRIEPGLEQQIALPRDSYL 869

Query: 2851 QDYFGDLAKYLRVGPPLYFVVKDFNYSLESEQTNQLCSISQCDSNSLLNEITRASLTAES 3030
            Q YF ++++YLRVGPPLYFVVKD+NYSLES+ TNQLCSISQCDSNSLLNEI+RASL  +S
Sbjct: 870  QGYFSNISEYLRVGPPLYFVVKDYNYSLESKHTNQLCSISQCDSNSLLNEISRASLVPKS 929

Query: 3031 SYIAKPAASWLDDFLIWLSPEAFSCCRKFVNGSYXXXXXXXXXXXXGDSSCGMGGICKDC 3210
            SYIAKPAASWLDDFL+W+SPEAFSCCRKFVNGSY             +  CG+GG+CKDC
Sbjct: 930  SYIAKPAASWLDDFLVWISPEAFSCCRKFVNGSYCPPDDQPPCCFPDEGPCGLGGVCKDC 989

Query: 3211 TTCFRHSDLQDGRPSTSQFKEKLPWFLKALPSSNCAKGGNGAYTSSVDLTGYDSGIIQAS 3390
            TTCFRHSDL + RP+T+QF+EKLPWFL ALPS++CAKGG+GAYT+SVDL G+ SG+IQAS
Sbjct: 990  TTCFRHSDLVNDRPTTAQFREKLPWFLDALPSADCAKGGHGAYTNSVDLNGFQSGVIQAS 1049

Query: 3391 SFRTYHTPLNKQSDYVNGMRAAREFSSEVSKSLKMQIFPYSVFYIFFEQYLDIWKTALVN 3570
             FRTYHTP+N+Q DYVN +RAAR+F S +S SLKM IFPYSVFYIFFEQYLDIWK AL+N
Sbjct: 1050 EFRTYHTPVNRQGDYVNALRAARDFCSRISASLKMDIFPYSVFYIFFEQYLDIWKIALIN 1109

Query: 3571 ILIGLGAVFIVCSVITCSFWTSTIILVVLAMIVIDMMGVMAILKIQLNAISVVNLVMSIG 3750
            + + LGAVF+VC +IT S W+S IIL+VL MIV+D+MGVMAIL IQLNA+SVVNLVMSIG
Sbjct: 1110 LAVALGAVFVVCLIITSSLWSSAIILLVLVMIVLDIMGVMAILGIQLNAVSVVNLVMSIG 1169

Query: 3751 IAVEFCVHITHSFSVSCGDRGTRARAALCTMGASIFSGITLTKLVGVIVLRFARSEIFVV 3930
            IAVEFCVHI H+F VS GDR  RA+ ALCTMGAS+FSGITLTKLVGV+VL FA SEIFVV
Sbjct: 1170 IAVEFCVHIAHAFMVSTGDRSQRAKIALCTMGASVFSGITLTKLVGVLVLCFATSEIFVV 1229

Query: 3931 YYFQMYLALVLLGFLH 3978
            YYFQMYLALV++GFLH
Sbjct: 1230 YYFQMYLALVIIGFLH 1245


>gb|KHN29878.1| Niemann-Pick C1 protein [Glycine soja]
          Length = 1720

 Score = 1648 bits (4268), Expect = 0.0
 Identities = 813/1232 (65%), Positives = 979/1232 (79%), Gaps = 7/1232 (0%)
 Frame = +1

Query: 304  RILAGARPEKISAEGYCSMYGICEKRSDGKPLNCPSNTPSVKPDKLLSSKVQSLCPTITG 483
            R  AGA   K S E YC+MY IC +RSDGK LNCP  +PSVKPD LLS+K+QSLCPTITG
Sbjct: 477  RAAAGAVRAKHSEE-YCAMYDICGQRSDGKALNCPYGSPSVKPDDLLSAKIQSLCPTITG 535

Query: 484  NVCCTADQFDTLRGQVQQAIPFLVGCPACLRNFLNVFCELSCSPNQSLFINVTSVMKGSN 663
            NVCCTADQFDTLR    QA+P LVGCPACLRNFLN+FCELSCSPNQSLFINVTS+ +   
Sbjct: 536  NVCCTADQFDTLR---VQAVPILVGCPACLRNFLNLFCELSCSPNQSLFINVTSISEVDG 592

Query: 664  TTTVDGIDLYITSTYGEALYNSCKDVKFGTMNTRAMDFIGGGAQNYNEWFAFIGKQAGVG 843
             TTVDGID ++T T+G+ LY SCKDVKFGTMNTRA+DF+G GA N+ EW  F+G++   G
Sbjct: 593  NTTVDGIDYHLTETFGQGLYESCKDVKFGTMNTRAIDFVGAGASNFKEWAEFLGQKVPPG 652

Query: 844  EIGSPYAIDFRSNISDSSGMKPMNVTVHSCGDLSLGCSCGDCPSSSVCSESATPASHKQG 1023
              GSPY+I F++ I DSS MK MN +V+SC D SLGCSCGDCPSS VCS S  P+  ++ 
Sbjct: 653  FPGSPYSILFKTAILDSSPMKLMNASVYSCNDTSLGCSCGDCPSSPVCSGSE-PSPPRKD 711

Query: 1024 SCHVKMGSLEVNCLEFSLAVVYIVFISVLLLWGLLHRKRVKEGPSSKTNPLVN--VKDEN 1197
             C + +GSL+V C++FS+A++YIV + VL  W LL R R +    S   PL++  V + +
Sbjct: 712  PCSIGIGSLKVRCVDFSIAILYIVLVFVLFGWALLQRTRGRRRLGSSAEPLLDDMVGEGS 771

Query: 1198 EPVNKQETSIQPVQI----PEGPPAVQALQPSIVQRYMSSFFRKYGAFVSRKPLLILCLS 1365
               N  +    P ++    P+G   VQ    S VQ  +SSF+R YG + +RKP ++LC S
Sbjct: 772  SFANLPKDGTHPAEVQWIDPQGQNVVQF---SFVQGCLSSFYRTYGRWAARKPTIVLCSS 828

Query: 1366 VAVPLLLCIGLVRFKVETRPEKLWVGPGSKAAEEKKYFDYHLAPFYRIEELILATVPGSK 1545
            +A+ +LLC+GL+RF+VETRPEKLWVGPGSKAAEEK++FD HLAPFYRIE+LI+AT+P SK
Sbjct: 829  LAIVVLLCLGLLRFEVETRPEKLWVGPGSKAAEEKEFFDSHLAPFYRIEQLIIATIPESK 888

Query: 1546 DGKSPSIVSDENMKLLFEIQKKIDGLKVNYSGSMISLSDICLKPLGDACATQSVLQYFKM 1725
             GK PSI+++EN++LLFEIQ+K+DG++ NYSG ++SLSDICLKPLGD CATQS+LQYF+M
Sbjct: 889  HGKPPSIITEENIELLFEIQEKVDGIRANYSGFLVSLSDICLKPLGDDCATQSILQYFQM 948

Query: 1726 DPENYNNYGGVEHADYCFLHYSSAETCLSAFQAPLDPSTALGGFSGNNFSEASAFVITYP 1905
            DP+NY+NYGGVEHA+YCF HY+S ETC SAF+APL+P+TALGGFSGNN+SEASAFVITYP
Sbjct: 949  DPDNYDNYGGVEHAEYCFQHYTSTETCFSAFKAPLEPTTALGGFSGNNYSEASAFVITYP 1008

Query: 1906 VNNEVERTGNENGKAVAWEKAFVRLVKEEIGPMVKLQNLTLSFSSESSVQEELKRESSAD 2085
            VNN + + G ENGKA+AWEKAF++L K+E+ PMV+  NLTLSFS+ESS++EELKRES+AD
Sbjct: 1009 VNNAITKVGGENGKAIAWEKAFIQLAKDELLPMVQSSNLTLSFSTESSIEEELKRESTAD 1068

Query: 2086 VITILVSYLVMFAYISFTLGDSPHXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXAIG 2265
            VITILV Y+VMFAYIS TLGD+P                                  AIG
Sbjct: 1069 VITILVGYIVMFAYISVTLGDTPPHPSFFFLSSKVLLGLLGVLLVMLSVLGSVGFFSAIG 1128

Query: 2266 VKSTLIIMEVIPFLVLAVGVDNMCILVHAFKRQPLDLPLEGRVSNALVEVGPSITLASLS 2445
            VKSTLIIMEVIPFLVLAVGVDNMCI+V A KRQP  LP+E ++SNA+ EVGPSITLASLS
Sbjct: 1129 VKSTLIIMEVIPFLVLAVGVDNMCIIVDAVKRQPSGLPVEEQISNAMGEVGPSITLASLS 1188

Query: 2446 EVLAFAVGSFIPMPACRVFSMXXXXXXXXXXXXQVTAFVALIVLDFLRAEDYRIDCIPCV 2625
            E+LAFAVGSF+ MPACRVFSM            Q+TAFVAL+ LDF+RA+D RIDC PCV
Sbjct: 1189 EILAFAVGSFVSMPACRVFSMIAALAVLLDFLLQITAFVALVTLDFMRAKDNRIDCFPCV 1248

Query: 2626 KVSL-SDESNKGDDPRNLGLVARYMKDVHAPMLEIPGVKMIVIAVFVAFSFASIDLCTRL 2802
            K++  S E N+G      GL+ RYMK+VHAP L + GVK++VIAVF AF+ ASI LCTR+
Sbjct: 1249 KLNPPSAEQNEGIRLERDGLLTRYMKEVHAPFLGLWGVKILVIAVFAAFTLASIALCTRI 1308

Query: 2803 QPGLEQQVVLPRDSYLQDYFGDLAKYLRVGPPLYFVVKDFNYSLESEQTNQLCSISQCDS 2982
            + GLEQQ+ LPRDSYLQ YF ++++YLRVGPPLYFVVKD+NYSLES+ TNQLCSIS CDS
Sbjct: 1309 EAGLEQQIALPRDSYLQGYFSNISEYLRVGPPLYFVVKDYNYSLESKHTNQLCSISHCDS 1368

Query: 2983 NSLLNEITRASLTAESSYIAKPAASWLDDFLIWLSPEAFSCCRKFVNGSYXXXXXXXXXX 3162
            NSLLNEI+RASL   SSYIAKPAASWLDDFL+W+SPEAFSCCRKF N SY          
Sbjct: 1369 NSLLNEISRASLVPTSSYIAKPAASWLDDFLVWISPEAFSCCRKFTNDSYCPPDDQPPCC 1428

Query: 3163 XXGDSSCGMGGICKDCTTCFRHSDLQDGRPSTSQFKEKLPWFLKALPSSNCAKGGNGAYT 3342
               +  CG+GG+CKDCTTCFRHSDL + RPST+QF+EKLPWFL ALPS++CAKGG+GAYT
Sbjct: 1429 LPDEGPCGLGGVCKDCTTCFRHSDLVNDRPSTAQFREKLPWFLDALPSADCAKGGHGAYT 1488

Query: 3343 SSVDLTGYDSGIIQASSFRTYHTPLNKQSDYVNGMRAAREFSSEVSKSLKMQIFPYSVFY 3522
            +SVDL GY+ G+IQAS FRTYHTPLN+Q DYVN +RAAR+FS+ +S SLKM IFPYSVFY
Sbjct: 1489 NSVDLNGYEGGVIQASEFRTYHTPLNRQGDYVNAIRAARDFSAIISSSLKMDIFPYSVFY 1548

Query: 3523 IFFEQYLDIWKTALVNILIGLGAVFIVCSVITCSFWTSTIILVVLAMIVIDMMGVMAILK 3702
            IFFEQYLDIWK AL+NI + LGA+F+VC +IT S W+S I+L+VL MI++D+MGVMAIL 
Sbjct: 1549 IFFEQYLDIWKLALINITVALGAIFVVCLIITSSVWSSAILLLVLIMIILDLMGVMAILG 1608

Query: 3703 IQLNAISVVNLVMSIGIAVEFCVHITHSFSVSCGDRGTRARAALCTMGASIFSGITLTKL 3882
            IQLNA+SVVNL+MSIGIAVEFCVHI H+F VS GDR  RA+ ALCTMGAS+FSGITLTKL
Sbjct: 1609 IQLNAVSVVNLIMSIGIAVEFCVHIVHAFMVSLGDRSQRAKTALCTMGASVFSGITLTKL 1668

Query: 3883 VGVIVLRFARSEIFVVYYFQMYLALVLLGFLH 3978
            VGV+VL F+ SEIFVVYYFQMYLALV++GFLH
Sbjct: 1669 VGVLVLCFSTSEIFVVYYFQMYLALVIIGFLH 1700


>ref|XP_020173434.1| Niemann-Pick C1 protein-like [Aegilops tauschii subsp. tauschii]
          Length = 1285

 Score = 1645 bits (4260), Expect = 0.0
 Identities = 823/1246 (66%), Positives = 970/1246 (77%), Gaps = 2/1246 (0%)
 Frame = +1

Query: 247  IQVNLHVFSASAQDSHSHFRILAGARPEKISAEGYCSMYGICEKRSDGKPLNCPSNTPSV 426
            +Q+   V   SAQ S+          P  + AEGYCSMYGIC  RSDGK LNC + T +V
Sbjct: 24   LQIVFLVHPTSAQQSNG--------APRVVPAEGYCSMYGICANRSDGKVLNCVNATKAV 75

Query: 427  KPDKLLSSKVQSLCPTITGNVCCTADQFDTLRGQVQQAIPFLVGCPACLRNFLNVFCELS 606
            KPD L S+++QSLCPTITG+VCCT DQFDTL  QVQQA+PFLVGCPACLRNFLN+FCE+S
Sbjct: 76   KPDTLFSTRIQSLCPTITGDVCCTVDQFDTLHQQVQQAVPFLVGCPACLRNFLNLFCEMS 135

Query: 607  CSPNQSLFINVTSVMKGSNTTTVDGIDLYITSTYGEALYNSCKDVKFGTMNTRAMDFIGG 786
            CSPNQSLFINVTS  +  N TTVDGID YITS YGE LYNSCK+VKFGT+NTRAMDF+GG
Sbjct: 136  CSPNQSLFINVTSAKQVDNITTVDGIDYYITSNYGEELYNSCKEVKFGTLNTRAMDFLGG 195

Query: 787  GAQNYNEWFAFIGKQAGVGEIGSPYAIDFRSNISDSSGMKPMNVTVHSCGDLSLGCSCGD 966
            GA+ Y EWFAF+G+QA   E GSPY I +R ++SDSSG+KP+N TV+SCGD SLGCSCGD
Sbjct: 196  GAKTYKEWFAFLGRQANPNEPGSPYLITYRPDLSDSSGVKPLNTTVYSCGDPSLGCSCGD 255

Query: 967  CPSSSVCSESATPASHKQGSCHVKMGSLEVNCLEFSLAVVYIVFISVLLLWGLLHRKRVK 1146
            CPSSSVC  S  P S  + SC VKMGSL+  CL+FSL VVYIVF+  +LLWGLL+R R +
Sbjct: 256  CPSSSVCMGSLLPQSKTETSCSVKMGSLKAECLDFSLVVVYIVFLCAILLWGLLYRTRGR 315

Query: 1147 EGPSSKTNPLVNVKDENEPVNKQETSIQPVQIPEGPPAVQALQPSIVQRYMSSFFRKYGA 1326
             G  S+T P  N  D++   N         Q+P      +A   SIVQ YMS+FFR++G 
Sbjct: 316  TGFPSQTKPPKNADDKSN--NNGNVPENSAQVP------KAASSSIVQTYMSTFFRRHGV 367

Query: 1327 FVSRKPLLILCLSVAVPLLLCIGLVRFKVETRPEKLWVGPGSKAAEEKKYFDYHLAPFYR 1506
            FV+R PLL+LC S+ VP+LLCIGL+RFKVETRPEKLWV PGS+ A EK+YFD HLAPFYR
Sbjct: 368  FVTRHPLLVLCASLLVPILLCIGLIRFKVETRPEKLWVSPGSQTAYEKQYFDSHLAPFYR 427

Query: 1507 IEELILATVPGSKDGKSPSIVSDENMKLLFEIQKKIDGLKVNYSGSMISLSDICLKPLGD 1686
            IE+L+LAT   S   ++P+IV+D N KLLF+IQKKID L+ NYSGS +SL+DICLKPL  
Sbjct: 428  IEQLVLAT-SASDQLEAPTIVNDNNFKLLFQIQKKIDDLRANYSGSTVSLADICLKPLST 486

Query: 1687 ACATQSVLQYFKMDPENYNNYGGVEHADYCFLHYSSAETCLSAFQAPLDPSTALGGFSGN 1866
             CATQSVLQYF++DP+ +++  G++HA +CF HYSS ETCLS FQ+P+DPST LGGF G+
Sbjct: 487  DCATQSVLQYFQLDPKKHDDL-GIDHAKFCFEHYSSEETCLSTFQSPIDPSTILGGFPGS 545

Query: 1867 NFSEASAFVITYPVNNEVERTGNENGKAVAWEKAFVRLVKEEIGPMVKLQNLTLSFSSES 2046
            NF+EASAFVITYPVNN+VE TG EN KA+AWE+A++ LVKEEI PMV  QNLTLSFSSES
Sbjct: 546  NFTEASAFVITYPVNNKVETTGQENAKAMAWERAYINLVKEEILPMVLAQNLTLSFSSES 605

Query: 2047 SVQEELKRESSADVITILVSYLVMFAYISFTLGDSPHXXXXXXXXXXXXXXXXXXXXXXX 2226
            S+++EL RES+AD ITI++SY+VMFAYISFTLGD P                        
Sbjct: 606  SIKDELNRESTADAITIVISYIVMFAYISFTLGDRPSRLWALFVSSKVLLGLSGVVLVML 665

Query: 2227 XXXXXXXXXXAIGVKSTLIIMEVIPFLVLAVGVDNMCILVHAFKRQPLDLPLEGRVSNAL 2406
                      A+GVKSTLIIMEVIPFLVLAVGVDNMCILVHA KRQP  + LE R+SNAL
Sbjct: 666  SVLGSMGFFSAVGVKSTLIIMEVIPFLVLAVGVDNMCILVHAVKRQPDGIVLEERISNAL 725

Query: 2407 VEVGPSITLASLSEVLAFAVGSFIPMPACRVFSMXXXXXXXXXXXXQVTAFVALIVLDFL 2586
            VEVGPSITLASL+EVLAF+V +  PMPA R FSM            QVTAFVALIV DF 
Sbjct: 726  VEVGPSITLASLAEVLAFSVSAINPMPATRAFSMFAAMAVLLDFVLQVTAFVALIVYDFR 785

Query: 2587 RAEDYRIDCIPCVKVSLSDESNKGDDPRNLGLVARYMKDVHAPMLEIPGVKMIVIAVFVA 2766
            RAED RIDC+PC ++  S  +      + L  VARYMKDVH P+L    VK IVIAVFV 
Sbjct: 786  RAEDGRIDCVPCARLKSSTVAGDNGGHQRLHFVARYMKDVHGPILGYRPVKFIVIAVFVG 845

Query: 2767 FSFASIDLCTRLQPGLEQQVVLPRDSYLQDYFGDLAKYLRVGPPLYFVVKDFNYSLESEQ 2946
             +FASI + TRLQPGLEQ++VLPRDSYLQ YF DL KY++VGPPLYFVVK+FNYS  SE 
Sbjct: 846  LAFASIAMSTRLQPGLEQKIVLPRDSYLQGYFDDLEKYMKVGPPLYFVVKNFNYSSASEN 905

Query: 2947 TNQLCSISQCDSNSLLNEITRASLTAESSYIAKPAASWLDDFLIWLSPEAFSCCRKFVNG 3126
            TNQ+CSI+QC+SNSLLNEI R SL+ E+SYIAKPAASWLDDFLIW+SPEAF CCRKFVNG
Sbjct: 906  TNQICSINQCNSNSLLNEIARQSLSPETSYIAKPAASWLDDFLIWMSPEAFGCCRKFVNG 965

Query: 3127 SY--XXXXXXXXXXXXGDSSCGMGGICKDCTTCFRHSDLQDGRPSTSQFKEKLPWFLKAL 3300
            +Y                 SC   G C +CTTCF HSDL +GRPST+QF+EKLPWFL AL
Sbjct: 966  NYCPPDDQPPCCQLDQDSGSCSSNGACNNCTTCFLHSDLHNGRPSTTQFREKLPWFLDAL 1025

Query: 3301 PSSNCAKGGNGAYTSSVDLTGYDSGIIQASSFRTYHTPLNKQSDYVNGMRAAREFSSEVS 3480
            PSS+C+KGG GAY++S+D +GY++GIIQAS+FRTYHTPLNKQ+DYVN +RAAR+FSS++S
Sbjct: 1026 PSSDCSKGGKGAYSTSLDHSGYENGIIQASAFRTYHTPLNKQTDYVNSLRAARDFSSQMS 1085

Query: 3481 KSLKMQIFPYSVFYIFFEQYLDIWKTALVNILIGLGAVFIVCSVITCSFWTSTIILVVLA 3660
            K L+M+IFPYSVF+IFFEQYL +WKTA++NI + LGAVF+VC V+T S W S IIL+VLA
Sbjct: 1086 KDLQMEIFPYSVFHIFFEQYLSVWKTAIMNICVCLGAVFVVCFVVTSSLWASAIILIVLA 1145

Query: 3661 MIVIDMMGVMAILKIQLNAISVVNLVMSIGIAVEFCVHITHSFSVSCGDRGTRARAALCT 3840
            MIV+D+MGVMA+L IQLNAIS+VNLVMSIGIAVEFCVHITH+F +  GDR  R R AL T
Sbjct: 1146 MIVLDLMGVMAVLGIQLNAISIVNLVMSIGIAVEFCVHITHAFMIGIGDRENRVRQALST 1205

Query: 3841 MGASIFSGITLTKLVGVIVLRFARSEIFVVYYFQMYLALVLLGFLH 3978
            MGAS+FSGITLTKLVGVIVLRFA+SE+FVVYYFQMYLALVL+GFLH
Sbjct: 1206 MGASVFSGITLTKLVGVIVLRFAKSEVFVVYYFQMYLALVLIGFLH 1251


>ref|XP_006652645.2| PREDICTED: Niemann-Pick C1 protein-like [Oryza brachyantha]
          Length = 1281

 Score = 1645 bits (4260), Expect = 0.0
 Identities = 825/1247 (66%), Positives = 978/1247 (78%), Gaps = 3/1247 (0%)
 Frame = +1

Query: 247  IQVNLHVFSASAQDSHSHFRILAGARPEKISAEGYCSMYGICEKRSDGKPLNCPSNTPSV 426
            +Q+   V   SAQ S+   R+          AEGYCSMYGIC KRSDGK LNC + T +V
Sbjct: 21   VQIVFLVPPTSAQQSNGTSRV---------PAEGYCSMYGICAKRSDGKVLNCVNATKAV 71

Query: 427  KPDKLLSSKVQSLCPTITGNVCCTADQFDTLRGQVQQAIPFLVGCPACLRNFLNVFCELS 606
            KPD L S+++QSLCPTITG+VCCT DQFDTL  QVQQAIPFLVGCPACLRNFLN+FCE+S
Sbjct: 72   KPDTLFSTRIQSLCPTITGDVCCTVDQFDTLHQQVQQAIPFLVGCPACLRNFLNLFCEMS 131

Query: 607  CSPNQSLFINVTSVMKGSNTTTVDGIDLYITSTYGEALYNSCKDVKFGTMNTRAMDFIGG 786
            CSPNQSLFINVTSV + +NT TV+GID Y+TS YGE LY SCKDVKFGT+NTRAMDF+GG
Sbjct: 132  CSPNQSLFINVTSVKQVNNTMTVNGIDYYVTSNYGEELYKSCKDVKFGTLNTRAMDFLGG 191

Query: 787  GAQNYNEWFAFIGKQAGVGEIGSPYAIDFRSNISDSSGMKPMNVTVHSCGDLSLGCSCGD 966
            GA+NY +WFAF+G+QA V EIGSPY I F S+IS  S +KP+N T++SCGD SLGCSCGD
Sbjct: 192  GAKNYKDWFAFLGRQANVNEIGSPYLITFPSDISGMSSVKPLNATIYSCGDPSLGCSCGD 251

Query: 967  CPSSSVCSESATPASHKQGSCHVKMGSLEVNCLEFSLAVVYIVFISVLLLWGLLHRKRVK 1146
            CPSSSVC+ S  P  + + SC VKMGSL+  CL+FSL VVY+V + + L W  LHR R  
Sbjct: 252  CPSSSVCTGSLLPQLNTETSCSVKMGSLKAKCLDFSLVVVYLVLLGIFLFWAFLHRTR-- 309

Query: 1147 EGPSSKTNPLVNVKDENEPVNKQETSIQPVQIPE-GPPAVQALQPSIVQRYMSSFFRKYG 1323
                 +T PL N +D+    N  +      Q+ E     VQ+  PS++Q YMS+FFRK+G
Sbjct: 310  -----RTKPLKNAEDKLHSSNNGKIPGSSAQVSEVASTPVQSAHPSVIQTYMSTFFRKHG 364

Query: 1324 AFVSRKPLLILCLSVAVPLLLCIGLVRFKVETRPEKLWVGPGSKAAEEKKYFDYHLAPFY 1503
             FV++ PLL+L +S+ VP LLCIGLVRFKVE RPEKLWV  GS++A+EK+YFD HLAPFY
Sbjct: 365  IFVAKHPLLVLFVSLLVPTLLCIGLVRFKVEIRPEKLWVSSGSRSADEKQYFDSHLAPFY 424

Query: 1504 RIEELILATVPGSKDGKSPSIVSDENMKLLFEIQKKIDGLKVNYSGSMISLSDICLKPLG 1683
            RIE+L+LAT   S   ++P+IV+D NMKLLF+IQKKID L+ NYSGS +SL+DICLKPLG
Sbjct: 425  RIEQLVLATSE-SGGSEAPTIVNDNNMKLLFQIQKKIDDLRANYSGSTVSLADICLKPLG 483

Query: 1684 DACATQSVLQYFKMDPENYNNYGGVEHADYCFLHYSSAETCLSAFQAPLDPSTALGGFSG 1863
              CA+QSVLQYF++DP+ Y++ G ++HA +CF HY+S E CLS FQ+P+DPST LGGF+G
Sbjct: 484  TDCASQSVLQYFQLDPKKYDDLG-IDHAKFCFQHYTSEEKCLSTFQSPIDPSTILGGFAG 542

Query: 1864 NNFSEASAFVITYPVNNEVERTGNENGKAVAWEKAFVRLVKEEIGPMVKLQNLTLSFSSE 2043
            NNF++ASAFVITYPVNN+VE TG ENGKA+AWE+A+V LVKEEI PMV  QNLTLSFSSE
Sbjct: 543  NNFTQASAFVITYPVNNKVETTGQENGKAIAWERAYVNLVKEEILPMVLAQNLTLSFSSE 602

Query: 2044 SSVQEELKRESSADVITILVSYLVMFAYISFTLGDSPHXXXXXXXXXXXXXXXXXXXXXX 2223
            SS+Q+EL RES+AD ITI++SY+VMFAYISFTLGD P                       
Sbjct: 603  SSIQDELNRESTADAITIVISYIVMFAYISFTLGDRPSHLLSLFISSKVLLGLSGVVLVM 662

Query: 2224 XXXXXXXXXXXAIGVKSTLIIMEVIPFLVLAVGVDNMCILVHAFKRQPLDLPLEGRVSNA 2403
                       AIGVKSTLIIMEVIPFLVLAVGVDNMCILVHA KRQP    LE R+S A
Sbjct: 663  LSVLGSMGFFSAIGVKSTLIIMEVIPFLVLAVGVDNMCILVHAVKRQPDGFDLEERISTA 722

Query: 2404 LVEVGPSITLASLSEVLAFAVGSFIPMPACRVFSMXXXXXXXXXXXXQVTAFVALIVLDF 2583
            LVEVGPSITLASL+EVLAFAV +  PMPA RVFSM            QV+AFVALIVLDF
Sbjct: 723  LVEVGPSITLASLAEVLAFAVSAINPMPATRVFSMFAALAVLLDFLLQVSAFVALIVLDF 782

Query: 2584 LRAEDYRIDCIPCVKVSLSDESNKGDDPRNLGLVARYMKDVHAPMLEIPGVKMIVIAVFV 2763
             RA+D RIDC+PC +V  +  ++ G + + L L+ARYMKDVHAP+L    VK IVIAVFV
Sbjct: 783  RRAQDGRIDCVPCARVKSNVVASNGGNHQGLPLLARYMKDVHAPILGYRAVKFIVIAVFV 842

Query: 2764 AFSFASIDLCTRLQPGLEQQVVLPRDSYLQDYFGDLAKYLRVGPPLYFVVKDFNYSLESE 2943
             FSFASI L TRLQPGLEQ++VLPRDSYLQ+YF DLA Y++VGPPLYF+VK+FNYS  SE
Sbjct: 843  GFSFASIALSTRLQPGLEQKIVLPRDSYLQNYFDDLATYMKVGPPLYFIVKNFNYSSLSE 902

Query: 2944 QTNQLCSISQCDSNSLLNEITRASLTAESSYIAKPAASWLDDFLIWLSPEAFSCCRKFVN 3123
             TNQ+CSI+QC+SNSLLNEI + SL+ E+SYIAKPAASWLDDFLIW+SPEAF CCRKFVN
Sbjct: 903  HTNQICSINQCNSNSLLNEIAKQSLSPETSYIAKPAASWLDDFLIWMSPEAFGCCRKFVN 962

Query: 3124 GSYXXXXXXXXXXXXGD--SSCGMGGICKDCTTCFRHSDLQDGRPSTSQFKEKLPWFLKA 3297
            GSY                SSC   G C +CTTCF  SDL +GRPST+QF+EKLPWFL A
Sbjct: 963  GSYCPPDDQAPCCQHDQDSSSCSSSGACNNCTTCFLRSDLHNGRPSTTQFEEKLPWFLDA 1022

Query: 3298 LPSSNCAKGGNGAYTSSVDLTGYDSGIIQASSFRTYHTPLNKQSDYVNGMRAAREFSSEV 3477
            LPSS+C+KGG GAY++S+DL GY+SGII+AS+FRTYHTPLNKQSDYVN M+AAR+FSS++
Sbjct: 1023 LPSSDCSKGGKGAYSTSLDLNGYESGIIKASAFRTYHTPLNKQSDYVNSMKAARDFSSKM 1082

Query: 3478 SKSLKMQIFPYSVFYIFFEQYLDIWKTALVNILIGLGAVFIVCSVITCSFWTSTIILVVL 3657
            S+ L+MQIFPYSVFYIFFEQYL +WK A++NI + LG VF+VC ++T S W S IILVVL
Sbjct: 1083 SRDLQMQIFPYSVFYIFFEQYLGVWKMAIMNICVCLGTVFVVCFIVTSSLWASIIILVVL 1142

Query: 3658 AMIVIDMMGVMAILKIQLNAISVVNLVMSIGIAVEFCVHITHSFSVSCGDRGTRARAALC 3837
            AMIV+D+MGVMAIL IQLNAISVVNLVMSIGIAVEFCVHITH+F +  G+R  RAR +L 
Sbjct: 1143 AMIVLDLMGVMAILGIQLNAISVVNLVMSIGIAVEFCVHITHAFMIGTGNRENRARQSLS 1202

Query: 3838 TMGASIFSGITLTKLVGVIVLRFARSEIFVVYYFQMYLALVLLGFLH 3978
            TMGAS+FSGITLTKLVGVIVLRFA+SE+FVVYYFQMYLALV++GFLH
Sbjct: 1203 TMGASVFSGITLTKLVGVIVLRFAKSEVFVVYYFQMYLALVIIGFLH 1249