BLASTX 2.2.25 [Feb-01-2011]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= Mentha26_contig00017769
         (305 letters)

Database: ./nr 
           38,876,450 sequences; 13,856,398,315 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

ref|XP_002276633.2| PREDICTED: protein RRP5 homolog [Vitis vinif...   159   3e-37
emb|CBI29966.3| unnamed protein product [Vitis vinifera]              159   3e-37
ref|XP_007029112.1| RNA binding,RNA binding isoform 1 [Theobroma...   157   2e-36
ref|XP_004514152.1| PREDICTED: protein RRP5 homolog [Cicer ariet...   155   6e-36
ref|XP_004234751.1| PREDICTED: protein RRP5 homolog [Solanum lyc...   155   7e-36
ref|XP_002884876.1| S1 RNA-binding domain-containing protein [Ar...   154   9e-36
ref|XP_006429952.1| hypothetical protein CICLE_v10013867mg [Citr...   154   1e-35
ref|XP_002322744.2| hypothetical protein POPTR_0016s06250g [Popu...   152   4e-35
ref|XP_006407387.1| hypothetical protein EUTSA_v10019877mg [Eutr...   152   5e-35
ref|XP_006481689.1| PREDICTED: protein RRP5 homolog isoform X2 [...   152   6e-35
ref|XP_006481688.1| PREDICTED: protein RRP5 homolog isoform X1 [...   152   6e-35
dbj|BAB03107.1| pre-rRNA processing protein RRP5 [Arabidopsis th...   152   6e-35
ref|NP_187803.4| protein ribosomal RNA processing 5 [Arabidopsis...   152   6e-35
gb|AAF23213.1|AC016795_26 putative pre-rRNA processing protein, ...   152   6e-35
ref|XP_002531584.1| programmed cell death protein, putative [Ric...   151   8e-35
ref|XP_006587177.1| PREDICTED: protein RRP5 homolog isoform X3 [...   150   2e-34
ref|XP_006587176.1| PREDICTED: protein RRP5 homolog isoform X2 [...   150   2e-34
ref|XP_006587175.1| PREDICTED: protein RRP5 homolog isoform X1 [...   150   2e-34
ref|XP_007145812.1| hypothetical protein PHAVU_007G270000g [Phas...   148   7e-34
ref|XP_006575180.1| PREDICTED: protein RRP5 homolog isoform X2 [...   148   9e-34

>ref|XP_002276633.2| PREDICTED: protein RRP5 homolog [Vitis vinifera]
          Length = 1879

 Score =  159 bits (403), Expect = 3e-37
 Identities = 73/101 (72%), Positives = 89/101 (88%)
 Frame = -3

Query: 303  LVDDLLNRMTRKFKQSCKVWLKKIKSLVKINSDGVQSVVERALKALPRRKHIKFITQTAI 124
            L D+LL +MT+KFK SCKVWL+++++++K + DGVQ V+ RAL  LPR KHIKFI+QTAI
Sbjct: 1722 LADELLEKMTKKFKHSCKVWLRRVQNVLKQHQDGVQPVINRALLCLPRHKHIKFISQTAI 1781

Query: 123  EEFKNGVPDRGRSLFENMLREYPKRTDLWSVYIDQEIRLGD 1
             EFK+GVPDRGRS+FE MLREYPKRTDLWSVY+DQEIRLGD
Sbjct: 1782 LEFKSGVPDRGRSMFEGMLREYPKRTDLWSVYLDQEIRLGD 1822


>emb|CBI29966.3| unnamed protein product [Vitis vinifera]
          Length = 1862

 Score =  159 bits (403), Expect = 3e-37
 Identities = 73/101 (72%), Positives = 89/101 (88%)
 Frame = -3

Query: 303  LVDDLLNRMTRKFKQSCKVWLKKIKSLVKINSDGVQSVVERALKALPRRKHIKFITQTAI 124
            L D+LL +MT+KFK SCKVWL+++++++K + DGVQ V+ RAL  LPR KHIKFI+QTAI
Sbjct: 1705 LADELLEKMTKKFKHSCKVWLRRVQNVLKQHQDGVQPVINRALLCLPRHKHIKFISQTAI 1764

Query: 123  EEFKNGVPDRGRSLFENMLREYPKRTDLWSVYIDQEIRLGD 1
             EFK+GVPDRGRS+FE MLREYPKRTDLWSVY+DQEIRLGD
Sbjct: 1765 LEFKSGVPDRGRSMFEGMLREYPKRTDLWSVYLDQEIRLGD 1805


>ref|XP_007029112.1| RNA binding,RNA binding isoform 1 [Theobroma cacao]
            gi|508717717|gb|EOY09614.1| RNA binding,RNA binding
            isoform 1 [Theobroma cacao]
          Length = 1824

 Score =  157 bits (396), Expect = 2e-36
 Identities = 73/101 (72%), Positives = 87/101 (86%)
 Frame = -3

Query: 303  LVDDLLNRMTRKFKQSCKVWLKKIKSLVKINSDGVQSVVERALKALPRRKHIKFITQTAI 124
            L D+LL++MTRKFK SCKVWL++++ L+    DGVQSVV RAL  LPR KHIKFI+QTAI
Sbjct: 1667 LADELLDKMTRKFKHSCKVWLRRVQMLLMQQQDGVQSVVNRALLCLPRHKHIKFISQTAI 1726

Query: 123  EEFKNGVPDRGRSLFENMLREYPKRTDLWSVYIDQEIRLGD 1
             EFK+GVPDRGRS+FE +LREYPKRTDLWS+Y+D EIRLGD
Sbjct: 1727 LEFKSGVPDRGRSMFEGILREYPKRTDLWSIYLDXEIRLGD 1767


>ref|XP_004514152.1| PREDICTED: protein RRP5 homolog [Cicer arietinum]
          Length = 1907

 Score =  155 bits (392), Expect = 6e-36
 Identities = 74/101 (73%), Positives = 86/101 (85%)
 Frame = -3

Query: 303  LVDDLLNRMTRKFKQSCKVWLKKIKSLVKINSDGVQSVVERALKALPRRKHIKFITQTAI 124
            L D+LLN+MT+KFK SCKVWL++++SL+    D VQ VV RAL +LPRRKHIKFI+QTAI
Sbjct: 1750 LADELLNKMTKKFKHSCKVWLRRVQSLLLQKQDAVQPVVNRALLSLPRRKHIKFISQTAI 1809

Query: 123  EEFKNGVPDRGRSLFENMLREYPKRTDLWSVYIDQEIRLGD 1
             EFK GVPDRGRSLFE +LREYPKRTDLWSVY+DQEI L D
Sbjct: 1810 LEFKTGVPDRGRSLFEGILREYPKRTDLWSVYLDQEIHLKD 1850


>ref|XP_004234751.1| PREDICTED: protein RRP5 homolog [Solanum lycopersicum]
          Length = 1869

 Score =  155 bits (391), Expect = 7e-36
 Identities = 75/101 (74%), Positives = 85/101 (84%)
 Frame = -3

Query: 303  LVDDLLNRMTRKFKQSCKVWLKKIKSLVKINSDGVQSVVERALKALPRRKHIKFITQTAI 124
            L D+LLN+M +KFK SCKVWL++ + L+K   DGVQSVV RAL +LP  KHI FITQTAI
Sbjct: 1712 LTDELLNKMVKKFKHSCKVWLRRTQWLLKQKQDGVQSVVNRALLSLPAHKHINFITQTAI 1771

Query: 123  EEFKNGVPDRGRSLFENMLREYPKRTDLWSVYIDQEIRLGD 1
             EFK GVPDRGRSLFE MLREYPKRTDLWSVY+DQEIRLG+
Sbjct: 1772 LEFKCGVPDRGRSLFEKMLREYPKRTDLWSVYLDQEIRLGN 1812


>ref|XP_002884876.1| S1 RNA-binding domain-containing protein [Arabidopsis lyrata subsp.
            lyrata] gi|297330716|gb|EFH61135.1| S1 RNA-binding
            domain-containing protein [Arabidopsis lyrata subsp.
            lyrata]
          Length = 1843

 Score =  154 bits (390), Expect = 9e-36
 Identities = 74/101 (73%), Positives = 87/101 (86%)
 Frame = -3

Query: 303  LVDDLLNRMTRKFKQSCKVWLKKIKSLVKINSDGVQSVVERALKALPRRKHIKFITQTAI 124
            LVD LL+ M +KFKQSCK+WL+KI+S ++ N +G+QSVV RAL  LPR KHIKFI+QTAI
Sbjct: 1686 LVDKLLDEMVKKFKQSCKIWLRKIQSSLQQNEEGIQSVVNRALLCLPRHKHIKFISQTAI 1745

Query: 123  EEFKNGVPDRGRSLFENMLREYPKRTDLWSVYIDQEIRLGD 1
             EFK GV DRGRSLFE +LREYPKRTDLWSVY+DQEIRLG+
Sbjct: 1746 LEFKCGVADRGRSLFEGVLREYPKRTDLWSVYLDQEIRLGE 1786


>ref|XP_006429952.1| hypothetical protein CICLE_v10013867mg [Citrus clementina]
            gi|557532009|gb|ESR43192.1| hypothetical protein
            CICLE_v10013867mg [Citrus clementina]
          Length = 1935

 Score =  154 bits (389), Expect = 1e-35
 Identities = 71/101 (70%), Positives = 88/101 (87%)
 Frame = -3

Query: 303  LVDDLLNRMTRKFKQSCKVWLKKIKSLVKINSDGVQSVVERALKALPRRKHIKFITQTAI 124
            L D+LL +M +KFK SCKVWL++++ L+K   +GVQ+VV+RAL +LPR KHIKFI+QTAI
Sbjct: 1778 LADELLYKMIKKFKHSCKVWLRRVQRLLKQQQEGVQAVVQRALLSLPRHKHIKFISQTAI 1837

Query: 123  EEFKNGVPDRGRSLFENMLREYPKRTDLWSVYIDQEIRLGD 1
             EFKNGV DRGRS+FE +LREYPKRTDLWS+Y+DQEIRLGD
Sbjct: 1838 LEFKNGVADRGRSMFEGILREYPKRTDLWSIYLDQEIRLGD 1878


>ref|XP_002322744.2| hypothetical protein POPTR_0016s06250g [Populus trichocarpa]
            gi|550320958|gb|EEF04505.2| hypothetical protein
            POPTR_0016s06250g [Populus trichocarpa]
          Length = 1856

 Score =  152 bits (385), Expect = 4e-35
 Identities = 72/101 (71%), Positives = 86/101 (85%)
 Frame = -3

Query: 303  LVDDLLNRMTRKFKQSCKVWLKKIKSLVKINSDGVQSVVERALKALPRRKHIKFITQTAI 124
            L ++LL++M +KFK SCK WLK++K L+K   DGVQSVV+RAL  LPR KHIKFI+QTAI
Sbjct: 1699 LAEELLDKMIKKFKHSCKFWLKRVKWLLKQKQDGVQSVVQRALLCLPRHKHIKFISQTAI 1758

Query: 123  EEFKNGVPDRGRSLFENMLREYPKRTDLWSVYIDQEIRLGD 1
             EFK GV DRGR+LFE +LREYPKRTDLWSVY+DQEI+LGD
Sbjct: 1759 REFKCGVADRGRTLFEEILREYPKRTDLWSVYLDQEIKLGD 1799


>ref|XP_006407387.1| hypothetical protein EUTSA_v10019877mg [Eutrema salsugineum]
            gi|557108533|gb|ESQ48840.1| hypothetical protein
            EUTSA_v10019877mg [Eutrema salsugineum]
          Length = 1926

 Score =  152 bits (384), Expect = 5e-35
 Identities = 73/101 (72%), Positives = 85/101 (84%)
 Frame = -3

Query: 303  LVDDLLNRMTRKFKQSCKVWLKKIKSLVKINSDGVQSVVERALKALPRRKHIKFITQTAI 124
            L D LL+ M +KFKQSCKVWL+K++S +K   +G+QSVV RAL  LPR KHIKFI+QTAI
Sbjct: 1769 LADKLLDEMIKKFKQSCKVWLRKVQSYLKQKEEGIQSVVNRALLCLPRHKHIKFISQTAI 1828

Query: 123  EEFKNGVPDRGRSLFENMLREYPKRTDLWSVYIDQEIRLGD 1
             EFK GV DRGRSLFE +LREYPKRTDLWSVY+DQEIRLG+
Sbjct: 1829 LEFKCGVADRGRSLFEGVLREYPKRTDLWSVYLDQEIRLGE 1869


>ref|XP_006481689.1| PREDICTED: protein RRP5 homolog isoform X2 [Citrus sinensis]
          Length = 1923

 Score =  152 bits (383), Expect = 6e-35
 Identities = 70/101 (69%), Positives = 87/101 (86%)
 Frame = -3

Query: 303  LVDDLLNRMTRKFKQSCKVWLKKIKSLVKINSDGVQSVVERALKALPRRKHIKFITQTAI 124
            L D+LL +M +KFK SCKVWL++++ L+K   +GVQ+VV+RAL +LPR KHIKFI+QTAI
Sbjct: 1766 LADELLYKMIKKFKHSCKVWLRRVQRLLKQQQEGVQAVVQRALLSLPRHKHIKFISQTAI 1825

Query: 123  EEFKNGVPDRGRSLFENMLREYPKRTDLWSVYIDQEIRLGD 1
             EFKNGV DRGRS+FE +L EYPKRTDLWS+Y+DQEIRLGD
Sbjct: 1826 LEFKNGVADRGRSMFEGILSEYPKRTDLWSIYLDQEIRLGD 1866


>ref|XP_006481688.1| PREDICTED: protein RRP5 homolog isoform X1 [Citrus sinensis]
          Length = 1934

 Score =  152 bits (383), Expect = 6e-35
 Identities = 70/101 (69%), Positives = 87/101 (86%)
 Frame = -3

Query: 303  LVDDLLNRMTRKFKQSCKVWLKKIKSLVKINSDGVQSVVERALKALPRRKHIKFITQTAI 124
            L D+LL +M +KFK SCKVWL++++ L+K   +GVQ+VV+RAL +LPR KHIKFI+QTAI
Sbjct: 1777 LADELLYKMIKKFKHSCKVWLRRVQRLLKQQQEGVQAVVQRALLSLPRHKHIKFISQTAI 1836

Query: 123  EEFKNGVPDRGRSLFENMLREYPKRTDLWSVYIDQEIRLGD 1
             EFKNGV DRGRS+FE +L EYPKRTDLWS+Y+DQEIRLGD
Sbjct: 1837 LEFKNGVADRGRSMFEGILSEYPKRTDLWSIYLDQEIRLGD 1877


>dbj|BAB03107.1| pre-rRNA processing protein RRP5 [Arabidopsis thaliana]
          Length = 1765

 Score =  152 bits (383), Expect = 6e-35
 Identities = 73/101 (72%), Positives = 85/101 (84%)
 Frame = -3

Query: 303  LVDDLLNRMTRKFKQSCKVWLKKIKSLVKINSDGVQSVVERALKALPRRKHIKFITQTAI 124
            L D LL+ M +KFKQSCK+WL+KI+S +K N + +QSVV RAL  LPR KHIKFI+QTAI
Sbjct: 1608 LADKLLDEMIKKFKQSCKIWLRKIQSSLKQNEEAIQSVVNRALLCLPRHKHIKFISQTAI 1667

Query: 123  EEFKNGVPDRGRSLFENMLREYPKRTDLWSVYIDQEIRLGD 1
             EFK GV DRGRSLFE +LREYPKRTDLWSVY+DQEIRLG+
Sbjct: 1668 LEFKCGVADRGRSLFEGVLREYPKRTDLWSVYLDQEIRLGE 1708


>ref|NP_187803.4| protein ribosomal RNA processing 5 [Arabidopsis thaliana]
            gi|332641610|gb|AEE75131.1| protein ribosomal RNA
            processing 5 [Arabidopsis thaliana]
          Length = 1896

 Score =  152 bits (383), Expect = 6e-35
 Identities = 73/101 (72%), Positives = 85/101 (84%)
 Frame = -3

Query: 303  LVDDLLNRMTRKFKQSCKVWLKKIKSLVKINSDGVQSVVERALKALPRRKHIKFITQTAI 124
            L D LL+ M +KFKQSCK+WL+KI+S +K N + +QSVV RAL  LPR KHIKFI+QTAI
Sbjct: 1739 LADKLLDEMIKKFKQSCKIWLRKIQSSLKQNEEAIQSVVNRALLCLPRHKHIKFISQTAI 1798

Query: 123  EEFKNGVPDRGRSLFENMLREYPKRTDLWSVYIDQEIRLGD 1
             EFK GV DRGRSLFE +LREYPKRTDLWSVY+DQEIRLG+
Sbjct: 1799 LEFKCGVADRGRSLFEGVLREYPKRTDLWSVYLDQEIRLGE 1839


>gb|AAF23213.1|AC016795_26 putative pre-rRNA processing protein, 5' partial [Arabidopsis
            thaliana]
          Length = 1111

 Score =  152 bits (383), Expect = 6e-35
 Identities = 73/101 (72%), Positives = 85/101 (84%)
 Frame = -3

Query: 303  LVDDLLNRMTRKFKQSCKVWLKKIKSLVKINSDGVQSVVERALKALPRRKHIKFITQTAI 124
            L D LL+ M +KFKQSCK+WL+KI+S +K N + +QSVV RAL  LPR KHIKFI+QTAI
Sbjct: 954  LADKLLDEMIKKFKQSCKIWLRKIQSSLKQNEEAIQSVVNRALLCLPRHKHIKFISQTAI 1013

Query: 123  EEFKNGVPDRGRSLFENMLREYPKRTDLWSVYIDQEIRLGD 1
             EFK GV DRGRSLFE +LREYPKRTDLWSVY+DQEIRLG+
Sbjct: 1014 LEFKCGVADRGRSLFEGVLREYPKRTDLWSVYLDQEIRLGE 1054


>ref|XP_002531584.1| programmed cell death protein, putative [Ricinus communis]
            gi|223528780|gb|EEF30787.1| programmed cell death
            protein, putative [Ricinus communis]
          Length = 1330

 Score =  151 bits (382), Expect = 8e-35
 Identities = 71/101 (70%), Positives = 86/101 (85%)
 Frame = -3

Query: 303  LVDDLLNRMTRKFKQSCKVWLKKIKSLVKINSDGVQSVVERALKALPRRKHIKFITQTAI 124
            L D+LL+RM +KFK SCK+WL++++  +K   DGVQS V+RAL +LPR KHIKFI+Q AI
Sbjct: 1173 LADELLDRMVKKFKISCKIWLRRVQRHLKQEQDGVQSTVKRALLSLPRHKHIKFISQAAI 1232

Query: 123  EEFKNGVPDRGRSLFENMLREYPKRTDLWSVYIDQEIRLGD 1
             EFK GVPDRGRS+FE +LREYPKRTDLWSVY+DQEIRLGD
Sbjct: 1233 LEFKCGVPDRGRSMFEGILREYPKRTDLWSVYLDQEIRLGD 1273


>ref|XP_006587177.1| PREDICTED: protein RRP5 homolog isoform X3 [Glycine max]
          Length = 1907

 Score =  150 bits (378), Expect = 2e-34
 Identities = 69/101 (68%), Positives = 86/101 (85%)
 Frame = -3

Query: 303  LVDDLLNRMTRKFKQSCKVWLKKIKSLVKINSDGVQSVVERALKALPRRKHIKFITQTAI 124
            L D+LLN+MT+KFK SCKVWL++I+SL+K N DG+Q V++RA  +LP+ KHIKF +QTAI
Sbjct: 1750 LADELLNKMTKKFKHSCKVWLRRIQSLLKQNKDGIQPVIDRASLSLPKHKHIKFFSQTAI 1809

Query: 123  EEFKNGVPDRGRSLFENMLREYPKRTDLWSVYIDQEIRLGD 1
             EFK G PDRGRS+FE +LREYPKRTDLWSVY+DQEI+  D
Sbjct: 1810 LEFKVGFPDRGRSMFEKILREYPKRTDLWSVYLDQEIQHKD 1850


>ref|XP_006587176.1| PREDICTED: protein RRP5 homolog isoform X2 [Glycine max]
          Length = 1910

 Score =  150 bits (378), Expect = 2e-34
 Identities = 69/101 (68%), Positives = 86/101 (85%)
 Frame = -3

Query: 303  LVDDLLNRMTRKFKQSCKVWLKKIKSLVKINSDGVQSVVERALKALPRRKHIKFITQTAI 124
            L D+LLN+MT+KFK SCKVWL++I+SL+K N DG+Q V++RA  +LP+ KHIKF +QTAI
Sbjct: 1753 LADELLNKMTKKFKHSCKVWLRRIQSLLKQNKDGIQPVIDRASLSLPKHKHIKFFSQTAI 1812

Query: 123  EEFKNGVPDRGRSLFENMLREYPKRTDLWSVYIDQEIRLGD 1
             EFK G PDRGRS+FE +LREYPKRTDLWSVY+DQEI+  D
Sbjct: 1813 LEFKVGFPDRGRSMFEKILREYPKRTDLWSVYLDQEIQHKD 1853


>ref|XP_006587175.1| PREDICTED: protein RRP5 homolog isoform X1 [Glycine max]
          Length = 1911

 Score =  150 bits (378), Expect = 2e-34
 Identities = 69/101 (68%), Positives = 86/101 (85%)
 Frame = -3

Query: 303  LVDDLLNRMTRKFKQSCKVWLKKIKSLVKINSDGVQSVVERALKALPRRKHIKFITQTAI 124
            L D+LLN+MT+KFK SCKVWL++I+SL+K N DG+Q V++RA  +LP+ KHIKF +QTAI
Sbjct: 1754 LADELLNKMTKKFKHSCKVWLRRIQSLLKQNKDGIQPVIDRASLSLPKHKHIKFFSQTAI 1813

Query: 123  EEFKNGVPDRGRSLFENMLREYPKRTDLWSVYIDQEIRLGD 1
             EFK G PDRGRS+FE +LREYPKRTDLWSVY+DQEI+  D
Sbjct: 1814 LEFKVGFPDRGRSMFEKILREYPKRTDLWSVYLDQEIQHKD 1854


>ref|XP_007145812.1| hypothetical protein PHAVU_007G270000g [Phaseolus vulgaris]
            gi|561019002|gb|ESW17806.1| hypothetical protein
            PHAVU_007G270000g [Phaseolus vulgaris]
          Length = 1906

 Score =  148 bits (374), Expect = 7e-34
 Identities = 69/101 (68%), Positives = 85/101 (84%)
 Frame = -3

Query: 303  LVDDLLNRMTRKFKQSCKVWLKKIKSLVKINSDGVQSVVERALKALPRRKHIKFITQTAI 124
            L DDLLN+MT+KFK SCKVWL++I+SL+  N D +Q +++RA  +LP+ KHIKF +QTAI
Sbjct: 1749 LADDLLNKMTKKFKHSCKVWLRRIQSLLNQNQDEIQPLIDRASLSLPKHKHIKFFSQTAI 1808

Query: 123  EEFKNGVPDRGRSLFENMLREYPKRTDLWSVYIDQEIRLGD 1
             EFK GVPDRGRSLFE +LREYPKRTDLWSVY+DQEI+  D
Sbjct: 1809 LEFKAGVPDRGRSLFEKILREYPKRTDLWSVYLDQEIQHKD 1849


>ref|XP_006575180.1| PREDICTED: protein RRP5 homolog isoform X2 [Glycine max]
          Length = 1910

 Score =  148 bits (373), Expect = 9e-34
 Identities = 69/101 (68%), Positives = 86/101 (85%)
 Frame = -3

Query: 303  LVDDLLNRMTRKFKQSCKVWLKKIKSLVKINSDGVQSVVERALKALPRRKHIKFITQTAI 124
            L D+LLN+MT+KFK SCKVWL++I+SL+K N DG+Q V++RA  +LP+ KHIKF +QTAI
Sbjct: 1753 LADELLNKMTKKFKHSCKVWLRRIQSLLKQNQDGIQPVIDRASLSLPKHKHIKFFSQTAI 1812

Query: 123  EEFKNGVPDRGRSLFENMLREYPKRTDLWSVYIDQEIRLGD 1
             EFK GV DRGRS+FE +LREYPKRTDLWSVY+DQEI+  D
Sbjct: 1813 LEFKVGVLDRGRSMFEKILREYPKRTDLWSVYLDQEIQHKD 1853