BLASTX 2.2.25 [Feb-01-2011]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= Mentha25_contig00054207
         (859 letters)

Database: ./nr 
           38,876,450 sequences; 13,856,398,315 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gb|EPQ63370.1| Nucleosomal histone H3-Lys79 methylase [Blumeria ...   246   8e-63
emb|CCU81714.1| histone-lysine N-methyltransferase [Blumeria gra...   240   6e-61
gb|EPE35612.1| S-adenosyl-L-methionine-dependent methyltransfera...   197   4e-48
gb|EHK96665.1| putative Histone-lysine N-methyltransferase, H3 l...   193   6e-47
ref|XP_001274501.1| histone methylation protein Dot1, putative [...   181   2e-43
ref|XP_002144846.1| conserved hypothetical protein [Talaromyces ...   181   4e-43
ref|XP_001824052.2| histone-lysine N-methyltransferase, H3 lysin...   180   5e-43
ref|XP_002381134.1| histone H3 methyltransferase, putative [Aspe...   180   5e-43
gb|EQL02193.1| Histone methylation DOT1 [Ophiocordyceps sinensis...   179   2e-42
gb|EQB58942.1| histone methylation protein DOT1 [Colletotrichum ...   177   6e-42
gb|EPS32524.1| hypothetical protein PDE_07484 [Penicillium oxali...   177   6e-42
ref|XP_002621940.1| histone methylation protein Dot1 [Ajellomyce...   177   6e-42
gb|EZF33960.1| histone-lysine N-methyltransferase, H3 lysine-79 ...   176   1e-41
ref|XP_007278523.1| histone-lysine n-methyltransferase [Colletot...   176   1e-41
dbj|GAA91645.1| histone H3 methyltransferase [Aspergillus kawach...   176   1e-41
ref|XP_003067183.1| histone-lysine N-methyltransferase, H3 lysin...   176   1e-41
ref|XP_003022720.1| hypothetical protein TRV_03181 [Trichophyton...   175   2e-41
ref|XP_003044852.1| predicted protein [Nectria haematococca mpVI...   175   2e-41
ref|XP_001239604.1| hypothetical protein CIMG_09225 [Coccidioide...   174   4e-41
ref|XP_753440.1| conserved hypothetical protein [Aspergillus fum...   174   5e-41

>gb|EPQ63370.1| Nucleosomal histone H3-Lys79 methylase [Blumeria graminis f. sp.
           tritici 96224]
          Length = 506

 Score =  246 bits (628), Expect = 8e-63
 Identities = 127/245 (51%), Positives = 171/245 (69%), Gaps = 1/245 (0%)
 Frame = +1

Query: 127 RRELSRFVDKKRKICLENAFSGHSASIARMIHASALVXXXXXXXXXXXXXH-VVTLGLKY 303
           R+++ ++ +KKRK+ LE+AFS + +    +IHA+ +                VV + ++Y
Sbjct: 116 RQKMIKYANKKRKLNLEDAFSVNQSESLEIIHAADITSVDKRPKMDRNEFTAVVMVQVQY 175

Query: 304 PSSSNPERYALIFGNDFNPAEEIINVVRVVLDFYFPEDQAKCLKDSEKGLIRRLNKYYNI 483
           PS+S  ERY LI G++FNP +EIINV+  VL+ YF E+Q   LK  + G+IRRL K YN+
Sbjct: 176 PSASQLERYVLIPGDNFNPVQEIINVITNVLELYFSEEQEIPLKGPDNGIIRRLTKAYNL 235

Query: 484 FARDLTDIKPLVEFKNVVEIYNSIIEKKISDGTFIRNLGSAHHIPLYMVEFILQQVYARA 663
             +  +D   L +FK  VE YNS +++ + DG+  + L S   +PL MVE ILQQVYAR 
Sbjct: 236 HTKRSSDNNFLKDFKEAVEAYNSSLQRLLKDGSIGKRLDSTQTLPLDMVECILQQVYART 295

Query: 664 VSPKIEILKKYENGTDNVYGELLPPFVSKILSESGLKSESIFVDLGSGVGNVVLQAALEF 843
           VSPK+ ILK+YENGTDN+YGELLPPF+S+IL+E+ L  E +FVDLGSGVGNVVLQAALEF
Sbjct: 296 VSPKVNILKQYENGTDNIYGELLPPFISRILAEASLTCEDVFVDLGSGVGNVVLQAALEF 355

Query: 844 GCESW 858
           GCESW
Sbjct: 356 GCESW 360


>emb|CCU81714.1| histone-lysine N-methyltransferase [Blumeria graminis f. sp. hordei
           DH14]
          Length = 506

 Score =  240 bits (612), Expect = 6e-61
 Identities = 130/287 (45%), Positives = 183/287 (63%), Gaps = 1/287 (0%)
 Frame = +1

Query: 1   DRLSNKLSLRKSRIVKKRPXXXXXXXXXXXENNTVIGVKSYKRRELSRFVDKKRKICLEN 180
           D+   KL LR++      P           E+   +   +  R+++ ++ +KKRK+ L +
Sbjct: 78  DKSKRKLPLRRT----PAPQHPLSSDSSDAEDVPDLKTPACTRQKMIKYANKKRKLNLGD 133

Query: 181 AFSGHSASIARMIHASALVXXXXXXXXXXXXXH-VVTLGLKYPSSSNPERYALIFGNDFN 357
           AFS + +    +IHA+ +                VV + ++YPS+S  ERY L+ G++FN
Sbjct: 134 AFSVNQSESLEIIHAADITSVDKRPKMDRNDFPAVVMVQVQYPSASQLERYVLMPGDNFN 193

Query: 358 PAEEIINVVRVVLDFYFPEDQAKCLKDSEKGLIRRLNKYYNIFARDLTDIKPLVEFKNVV 537
           P +EIINV+  VL+ YF E+Q   LK  + G+IR+L K YN+  +  +D   L +FK  V
Sbjct: 194 PVQEIINVITNVLELYFSEEQKIPLKGPDNGIIRKLTKAYNLHTKGSSDNNFLNDFKEAV 253

Query: 538 EIYNSIIEKKISDGTFIRNLGSAHHIPLYMVEFILQQVYARAVSPKIEILKKYENGTDNV 717
           E YN+ +++ + DG+  + L S   +PL MVE ILQQVYAR VSPK+ ILK+YENGTDN+
Sbjct: 254 EAYNTSLQRLLKDGSIGKRLDSTQILPLDMVECILQQVYARTVSPKVNILKQYENGTDNI 313

Query: 718 YGELLPPFVSKILSESGLKSESIFVDLGSGVGNVVLQAALEFGCESW 858
           YGELLPPF+S+IL+E+ L  E +FVDLGSGVGNVVLQAALEFGCESW
Sbjct: 314 YGELLPPFISRILAEASLTCEDVFVDLGSGVGNVVLQAALEFGCESW 360


>gb|EPE35612.1| S-adenosyl-L-methionine-dependent methyltransferase [Glarea
           lozoyensis ATCC 20868]
          Length = 513

 Score =  197 bits (501), Expect = 4e-48
 Identities = 117/258 (45%), Positives = 155/258 (60%), Gaps = 13/258 (5%)
 Frame = +1

Query: 124 KRRELSRF---VDKKRKICLENAFS-GHSASIARMIHAS--ALVXXXXXXXXXXXXXHVV 285
           KRR +      VD KRK+    AFS         MIHA+    V               +
Sbjct: 110 KRRRVEAIPGNVDLKRKLRSRRAFSTDEDRGKFAMIHAADTTAVPRKTSTISESATIDDI 169

Query: 286 TLGLKYPSSSNPERYALIFGND-FNPAEEIINVVRVVLDFYFPEDQAKCLKDSEKGLIRR 462
           T+ L+YPS+S  ERY L FG D  +  +EII++ + V DFY  ++QAK   +   G IR+
Sbjct: 170 TVKLRYPSASQRERYDLEFGKDRIDSVQEIIDIAKTVADFYLTDEQAKPFLEPNSGYIRQ 229

Query: 463 LNKYYNIFARDLT--DIKP----LVEFKNVVEIYNSIIEKKISDGTFIRNLGSAHHIPLY 624
           L K  N  A +    +I P    L +FK  V+ YN+ ++K   D    +NL   HH+P  
Sbjct: 230 LEKARNNLANNKKRGEITPRPVLLNDFKAAVDQYNAALQKLRLDKVLEQNLDDKHHLPFN 289

Query: 625 MVEFILQQVYARAVSPKIEILKKYENGTDNVYGELLPPFVSKILSESGLKSESIFVDLGS 804
           MV+ IL QVY RAVSPK+++L++YENG DNVYGELLP  V+++L+E+ LKS+ +FVDLGS
Sbjct: 290 MVKLILNQVYERAVSPKVDLLRQYENGGDNVYGELLPKLVNQVLTETNLKSDQVFVDLGS 349

Query: 805 GVGNVVLQAALEFGCESW 858
           GVGNV LQAALEFGCESW
Sbjct: 350 GVGNVALQAALEFGCESW 367


>gb|EHK96665.1| putative Histone-lysine N-methyltransferase, H3 lysine-79 specific
           [Glarea lozoyensis 74030]
          Length = 421

 Score =  193 bits (491), Expect = 6e-47
 Identities = 101/199 (50%), Positives = 136/199 (68%), Gaps = 7/199 (3%)
 Frame = +1

Query: 283 VTLGLKYPSSSNPERYALIFGND-FNPAEEIINVVRVVLDFYFPEDQAKCLKDSEKGLIR 459
           +T+ L+YPS+S  ERY L FG D  +  +EII++ + V DFY  ++QAK   +   G IR
Sbjct: 77  ITVKLRYPSASQRERYDLEFGKDRIDSVQEIIDIAKTVADFYLTDEQAKPFLEPNSGYIR 136

Query: 460 RLNKYYNIFARDLT--DIKP----LVEFKNVVEIYNSIIEKKISDGTFIRNLGSAHHIPL 621
           +L K  N  A +    +I P    L +FK  V+ YN+ ++K   D    +NL   HH+P 
Sbjct: 137 QLEKARNNLANNKKRGEITPRPVLLNDFKAAVDQYNAALQKLRLDKVLEQNLDDKHHLPF 196

Query: 622 YMVEFILQQVYARAVSPKIEILKKYENGTDNVYGELLPPFVSKILSESGLKSESIFVDLG 801
            MV+ IL QVY RAVSPK+++L++YENG DNVYGELLP  V+++L+E+ LKS+ +FVDLG
Sbjct: 197 NMVKLILNQVYERAVSPKVDLLRQYENGGDNVYGELLPKLVNQVLTETNLKSDQVFVDLG 256

Query: 802 SGVGNVVLQAALEFGCESW 858
           SGVGNV LQAALEFGCESW
Sbjct: 257 SGVGNVALQAALEFGCESW 275


>ref|XP_001274501.1| histone methylation protein Dot1, putative [Aspergillus clavatus
           NRRL 1] gi|119402654|gb|EAW13075.1| histone methylation
           protein Dot1, putative [Aspergillus clavatus NRRL 1]
          Length = 504

 Score =  181 bits (460), Expect = 2e-43
 Identities = 104/243 (42%), Positives = 142/243 (58%), Gaps = 7/243 (2%)
 Frame = +1

Query: 151 DKKRKICLENAFSGHSASIARMIHASALVXXXXXXXXXXXXXHVVT----LGLKYPSSSN 318
           D  R+I    AFS  +     ++HA+ +V                +    + L+YPS+S 
Sbjct: 122 DLSRRIRSLKAFSEENVKPLPLVHAADIVSKQKAAGNFKRAFSGASGPTEILLQYPSASR 181

Query: 319 PERYALIF---GNDFNPAEEIINVVRVVLDFYFPEDQAKCLKDSEKGLIRRLNKYYNIFA 489
            ERY LI     +DF P ++I++V+ +V + Y PE +A    +   G+ RRL +     +
Sbjct: 182 KERYNLIVPRDNDDFKPTDDIVHVIDIVSENYIPETKADAFNNESTGIRRRLRRALAHSS 241

Query: 490 RDLTDIKPLVEFKNVVEIYNSIIEKKISDGTFIRNLGSAHHIPLYMVEFILQQVYARAVS 669
                     EF+  V  YN  IE+   DG+  R+L S H + L +VE IL Q+YAR VS
Sbjct: 242 EP--------EFREAVADYNHEIERLRRDGSIARHLDSMHRLSLPLVERILTQIYARTVS 293

Query: 670 PKIEILKKYENGTDNVYGELLPPFVSKILSESGLKSESIFVDLGSGVGNVVLQAALEFGC 849
           P+++ L++YENGTDNVYGELLP F+S I  E+GLKS  +FVDLGSGVGNVVLQAALE GC
Sbjct: 294 PRVDALRQYENGTDNVYGELLPRFISTIFKETGLKSGQVFVDLGSGVGNVVLQAALEIGC 353

Query: 850 ESW 858
           ESW
Sbjct: 354 ESW 356


>ref|XP_002144846.1| conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
           gi|210074244|gb|EEA28331.1| conserved hypothetical
           protein [Talaromyces marneffei ATCC 18224]
          Length = 512

 Score =  181 bits (458), Expect = 4e-43
 Identities = 106/266 (39%), Positives = 148/266 (55%), Gaps = 10/266 (3%)
 Frame = +1

Query: 91  ENNTVIGVKSYKRRELSRFV--DKKRKICLENAFSGHSASIARMIHASALVXXXXXXXXX 264
           +N+T    +  KR +LS  V  D  R+I    AFS       +M+HA+ +          
Sbjct: 106 DNDTDTSFEVRKRTKLSDSVEPDFARRIRSVEAFSKDGPKALKMVHAADITAAKAVGKYK 165

Query: 265 XXXXHVVTLG-----LKYPSSSNPERYALIF---GNDFNPAEEIINVVRVVLDFYFPEDQ 420
                    G     L+YPS+   ERY L+     +DF P ++I+ VV +V  +Y PED 
Sbjct: 166 PAFEKGADKGPSEIRLQYPSTVKGERYQLVVPKENDDFKPLDDIVQVVEMVSQYYIPEDM 225

Query: 421 AKCLKDSEKGLIRRLNKYYNIFARDLTDIKPLVEFKNVVEIYNSIIEKKISDGTFIRNLG 600
                    G+ RR+ + +   +          EF+ V+  YN  ++  +SDG+  ++L 
Sbjct: 226 LDEFNHESTGIKRRIRRAFAHASE--------AEFREVISDYNRAVQIYVSDGSIAKHLD 277

Query: 601 SAHHIPLYMVEFILQQVYARAVSPKIEILKKYENGTDNVYGELLPPFVSKILSESGLKSE 780
             H + L +VE IL Q+Y+R VSP+++ L++YENGTDNVYGELLP FVS I  E+ LKS 
Sbjct: 278 ETHALQLPLVERILTQIYSRTVSPRVDSLRQYENGTDNVYGELLPRFVSTIFKETHLKSG 337

Query: 781 SIFVDLGSGVGNVVLQAALEFGCESW 858
            +FVDLGSGVGNVVLQAALE GCESW
Sbjct: 338 QVFVDLGSGVGNVVLQAALEIGCESW 363


>ref|XP_001824052.2| histone-lysine N-methyltransferase, H3 lysine-79 specific
           [Aspergillus oryzae RIB40]
          Length = 502

 Score =  180 bits (457), Expect = 5e-43
 Identities = 96/191 (50%), Positives = 123/191 (64%), Gaps = 3/191 (1%)
 Frame = +1

Query: 295 LKYPSSSNPERYALIFG---NDFNPAEEIINVVRVVLDFYFPEDQAKCLKDSEKGLIRRL 465
           L+YPS+S  ERY L+     +DF P ++I  V+  V   Y PED+A    +   G+ RRL
Sbjct: 172 LQYPSASPKERYNLVVPRDKDDFRPIDDIFQVIETVSQNYIPEDEADYFDNESTGIKRRL 231

Query: 466 NKYYNIFARDLTDIKPLVEFKNVVEIYNSIIEKKISDGTFIRNLGSAHHIPLYMVEFILQ 645
            +     +          EF+NVV  YN  IE+   DG+  + L S H + L +VE IL 
Sbjct: 232 RRALAHASE--------AEFRNVVTDYNEAIERLRRDGSIAQKLDSTHRLNLPLVERILT 283

Query: 646 QVYARAVSPKIEILKKYENGTDNVYGELLPPFVSKILSESGLKSESIFVDLGSGVGNVVL 825
           Q+Y+R VSP++E L++YENGTDNVYGELLP F+S I  E+GLKS  +FVDLGSGVGNVVL
Sbjct: 284 QIYSRTVSPRVESLRQYENGTDNVYGELLPRFISTIFKETGLKSGQVFVDLGSGVGNVVL 343

Query: 826 QAALEFGCESW 858
           QAALE GCESW
Sbjct: 344 QAALEIGCESW 354


>ref|XP_002381134.1| histone H3 methyltransferase, putative [Aspergillus flavus
           NRRL3357] gi|220692887|gb|EED49233.1| histone H3
           methyltransferase, putative [Aspergillus flavus
           NRRL3357] gi|391874239|gb|EIT83160.1| putative protein
           methyltransferase involved in meiosis and
           transcriptional silencing [Aspergillus oryzae 3.042]
          Length = 502

 Score =  180 bits (457), Expect = 5e-43
 Identities = 96/191 (50%), Positives = 123/191 (64%), Gaps = 3/191 (1%)
 Frame = +1

Query: 295 LKYPSSSNPERYALIFG---NDFNPAEEIINVVRVVLDFYFPEDQAKCLKDSEKGLIRRL 465
           L+YPS+S  ERY L+     +DF P ++I  V+  V   Y PED+A    +   G+ RRL
Sbjct: 172 LQYPSASPKERYNLVVPRDKDDFRPIDDIFQVIETVSQNYIPEDEADYFDNESTGIKRRL 231

Query: 466 NKYYNIFARDLTDIKPLVEFKNVVEIYNSIIEKKISDGTFIRNLGSAHHIPLYMVEFILQ 645
            +     +          EF+NVV  YN  IE+   DG+  + L S H + L +VE IL 
Sbjct: 232 RRALAHASE--------AEFRNVVTDYNDAIERLRRDGSIAQKLDSTHRLNLPLVERILT 283

Query: 646 QVYARAVSPKIEILKKYENGTDNVYGELLPPFVSKILSESGLKSESIFVDLGSGVGNVVL 825
           Q+Y+R VSP++E L++YENGTDNVYGELLP F+S I  E+GLKS  +FVDLGSGVGNVVL
Sbjct: 284 QIYSRTVSPRVESLRQYENGTDNVYGELLPRFISTIFKETGLKSGQVFVDLGSGVGNVVL 343

Query: 826 QAALEFGCESW 858
           QAALE GCESW
Sbjct: 344 QAALEIGCESW 354


>gb|EQL02193.1| Histone methylation DOT1 [Ophiocordyceps sinensis CO18]
          Length = 469

 Score =  179 bits (453), Expect = 2e-42
 Identities = 107/242 (44%), Positives = 140/242 (57%), Gaps = 3/242 (1%)
 Frame = +1

Query: 142 RFVDKKRKICLENAFSGHSASIARMIHASALVXXXXXXXXXXXXXHV-VTLGLKYPSSSN 318
           RF+D KRK+    AF G +  + R IHA  +                 V + L+YPS   
Sbjct: 100 RFLDPKRKLRNSRAFEGRNEHL-RFIHAVQVASLEAKCVPVMGAQKEDVAIELQYPSLQP 158

Query: 319 PERYALIFGND-FNPAEEIINVVRVVLDFYFPEDQAKCLKDSEKGLIRRLNKYYNIFARD 495
            ER+ L++G D  +  E  I +VR V + Y   ++A+   +   GLIRRL K  N     
Sbjct: 159 RERFELVWGRDKIDAVEASIRIVRHVAETYLSGEEAEPFTNPHSGLIRRLEKASN----- 213

Query: 496 LTDIKPLVEFKNVVEIYNSIIEKKISDGTFIRNLGSAHHIPLYMVEFILQQVYARAVSPK 675
             +I+ L  FK  +  YN  + + I DG   RNL + H +P  +V FIL Q+Y R V+PK
Sbjct: 214 -RNIQDLAGFKAALHEYNETLLELIEDGVVERNLDNMHELPRNLVAFILDQIYDRTVAPK 272

Query: 676 IEILKKYENGTDNVYGELLPPFVSKILSES-GLKSESIFVDLGSGVGNVVLQAALEFGCE 852
           +E+L KYENGTD VYGELL PFVS+IL E   + S+ +FVDLGSGVGNV LQAALE GCE
Sbjct: 273 VELLSKYENGTDYVYGELLHPFVSRILVEQMSMTSDHVFVDLGSGVGNVCLQAALEIGCE 332

Query: 853 SW 858
           SW
Sbjct: 333 SW 334


>gb|EQB58942.1| histone methylation protein DOT1 [Colletotrichum gloeosporioides
           Cg-14]
          Length = 489

 Score =  177 bits (448), Expect = 6e-42
 Identities = 108/254 (42%), Positives = 150/254 (59%), Gaps = 8/254 (3%)
 Frame = +1

Query: 121 YKRRELS--RFVDKKRKICLENAFSGHSASIARMIHASALVXXXXXXXXXXXXXHV---- 282
           +KR+ L+  + VD KR +   +AF      ++R+IHA+ L                    
Sbjct: 110 HKRQRLADGQLVDTKRVLTRASAFKEGLRDLSRLIHAADLTNLKTCPKAMRVLGATEQDD 169

Query: 283 VTLGLKYPSSSNPERYALIFGND-FNPAEEIINVVRVVLDFYFPEDQAKCLKDSEKGLIR 459
           V + L+YPS   PE Y LI+  D  N  E+I+ VV+ V D Y  E QA+  +D + G+IR
Sbjct: 170 VRVRLQYPSMYGPENYELIWEADKINSIEDILKVVQHVADVYLTEKQAEEFRDPDTGIIR 229

Query: 460 RLNKYYNIFARDLTDIKPLVEFKNVVEIYNSIIEKKISDGTFIRNLGSAHHIPLYMVEFI 639
           RL +     AR+  D++    FK  ++  N  I    +DGT  +NL + H +P  MV FI
Sbjct: 230 RLTR-----ARNTNDLRG---FKTALQDANRRIRALAADGTIRKNLDNMHGLPRDMVHFI 281

Query: 640 LQQVYARAVSPKIEILKKYENGTDNVYGELLPPFVSKILSE-SGLKSESIFVDLGSGVGN 816
           L+QVY R VSP +E LK+Y+NGTDNVYGEL   F+S++L E + + S+ +F+DLGSGVGN
Sbjct: 282 LRQVYERTVSPNVEKLKQYKNGTDNVYGELGELFISEVLQEKTRMTSDQVFIDLGSGVGN 341

Query: 817 VVLQAALEFGCESW 858
           VV QAALE GCESW
Sbjct: 342 VVFQAALEIGCESW 355


>gb|EPS32524.1| hypothetical protein PDE_07484 [Penicillium oxalicum 114-2]
          Length = 501

 Score =  177 bits (448), Expect = 6e-42
 Identities = 103/262 (39%), Positives = 144/262 (54%), Gaps = 6/262 (2%)
 Frame = +1

Query: 91  ENNTVIGVKSYKRRELSRFVDKKRKICLENAFSGHSASIARMIHASALVXXXXXXXXXXX 270
           +++T   ++   R   S   D +R+I    AFS  ++   +M+HA+ +            
Sbjct: 100 DSDTSFEMRKRARVSASAEPDPERRIRSVKAFSEEASRPFKMVHAADITSGQKAGKFKPA 159

Query: 271 XXHVVT---LGLKYPSSSNPERYALIFGND---FNPAEEIINVVRVVLDFYFPEDQAKCL 432
                    + L+YPS+S  ER+  +   D   F P ++I+ V+  V D Y P D+A   
Sbjct: 160 FGAASKPKEILLQYPSASRKERFDCMVPKDNDEFRPIDDIVQVIETVADHYIPSDKAAEF 219

Query: 433 KDSEKGLIRRLNKYYNIFARDLTDIKPLVEFKNVVEIYNSIIEKKISDGTFIRNLGSAHH 612
            D   G+ RRL +   + +          +F+  VE YN ++E+   DG   + L   H 
Sbjct: 220 NDETTGIRRRLRRAIALSSE--------TQFREAVEDYNKLVERLRIDGHIAKTLDETHR 271

Query: 613 IPLYMVEFILQQVYARAVSPKIEILKKYENGTDNVYGELLPPFVSKILSESGLKSESIFV 792
           + L  VE IL Q YAR VSP++E L++YENGTDNVYGELLP F+S I  E+ LKS  +FV
Sbjct: 272 MGLPWVERILNQTYARTVSPRVESLRQYENGTDNVYGELLPRFISDIFKETKLKSGHVFV 331

Query: 793 DLGSGVGNVVLQAALEFGCESW 858
           DLGSGVGNVVLQAALE GCESW
Sbjct: 332 DLGSGVGNVVLQAALEIGCESW 353


>ref|XP_002621940.1| histone methylation protein Dot1 [Ajellomyces dermatitidis
           SLH14081] gi|239590984|gb|EEQ73565.1| histone
           methylation protein Dot1 [Ajellomyces dermatitidis
           SLH14081] gi|531983970|gb|EQL34557.1| histone-lysine
           N-methyltransferase, H3 lysine-79 specific [Ajellomyces
           dermatitidis ATCC 26199]
          Length = 532

 Score =  177 bits (448), Expect = 6e-42
 Identities = 92/195 (47%), Positives = 127/195 (65%), Gaps = 3/195 (1%)
 Frame = +1

Query: 283 VTLGLKYPSSSNPERYALIFGND---FNPAEEIINVVRVVLDFYFPEDQAKCLKDSEKGL 453
           VT+ L+YP +S  E+Y L+   +   F P ++I+++V +V   Y PE+ A    D   G+
Sbjct: 196 VTVRLQYPGASQGEKYQLVVPREKEGFKPLDDIVHLVNIVSQNYIPEEYAHLFNDEATGI 255

Query: 454 IRRLNKYYNIFARDLTDIKPLVEFKNVVEIYNSIIEKKISDGTFIRNLGSAHHIPLYMVE 633
            RR       F R L       EF   ++ YN+ I +  +DG+  ++L + H +PL +VE
Sbjct: 256 NRR-------FRRALAHASQS-EFMEAIDEYNNTITRLRADGSIAKHLDTIHSLPLPLVE 307

Query: 634 FILQQVYARAVSPKIEILKKYENGTDNVYGELLPPFVSKILSESGLKSESIFVDLGSGVG 813
            IL Q+YAR VSP++E L++YENGTDNVYGELLP F+S+I  ++ LKS  +FVDLGSGVG
Sbjct: 308 RILNQIYARTVSPRVESLRRYENGTDNVYGELLPRFISEIFKQTKLKSNQVFVDLGSGVG 367

Query: 814 NVVLQAALEFGCESW 858
           NVVLQAALE GCESW
Sbjct: 368 NVVLQAALEIGCESW 382


>gb|EZF33960.1| histone-lysine N-methyltransferase, H3 lysine-79 specific
           [Trichophyton interdigitale H6]
          Length = 521

 Score =  176 bits (446), Expect = 1e-41
 Identities = 109/264 (41%), Positives = 146/264 (55%), Gaps = 8/264 (3%)
 Frame = +1

Query: 91  ENNTVIGVKSYKRRELSRFV--DKKRKICLENAFSGHSASIARMIHA---SALVXXXXXX 255
           E +  + ++  KR ++S     D KR++  E AFS  +     M+HA   +++       
Sbjct: 117 ETDESLDIRLSKRTKVSASAEPDLKRQLRSEIAFSETAEHSFPMVHALDIASIEKTPGFS 176

Query: 256 XXXXXXXHVVTLGLKYPSSSNPERYALIFGND---FNPAEEIINVVRVVLDFYFPEDQAK 426
                     T+ L+YP+ S  ERY L+   +   F P E+I+ VV  V   Y PEDQ  
Sbjct: 177 SAFKETSGCTTIALQYPTYSQRERYQLVIPRENDGFKPLEDIVQVVETVSHNYIPEDQIS 236

Query: 427 CLKDSEKGLIRRLNKYYNIFARDLTDIKPLVEFKNVVEIYNSIIEKKISDGTFIRNLGSA 606
              D   G IR L        R +    P  +F N V+ YN  I +   +G   ++L S 
Sbjct: 237 AFTDDSTGYIRLLR-------RAIKQESPK-DFWNAVKAYNGTIRRLRDEGVIAKHLDST 288

Query: 607 HHIPLYMVEFILQQVYARAVSPKIEILKKYENGTDNVYGELLPPFVSKILSESGLKSESI 786
           H + L  VE IL QVY+R VS ++E LKKYE+GTDNVYGELLP F+S I  ++ LKS+ +
Sbjct: 289 HSLSLPWVERILTQVYSRTVSLRVESLKKYESGTDNVYGELLPRFISDIFQKTHLKSDQV 348

Query: 787 FVDLGSGVGNVVLQAALEFGCESW 858
           FVDLGSGVGNVVLQAALE GCESW
Sbjct: 349 FVDLGSGVGNVVLQAALEVGCESW 372


>ref|XP_007278523.1| histone-lysine n-methyltransferase [Colletotrichum gloeosporioides
           Nara gc5] gi|429857522|gb|ELA32385.1| histone-lysine
           n-methyltransferase [Colletotrichum gloeosporioides Nara
           gc5]
          Length = 490

 Score =  176 bits (446), Expect = 1e-41
 Identities = 108/254 (42%), Positives = 149/254 (58%), Gaps = 8/254 (3%)
 Frame = +1

Query: 121 YKRRELS--RFVDKKRKICLENAFSGHSASIARMIHASALVXXXXXXXXXXXXXHV---- 282
           +KR+ L+  + VD KR +   +AF      ++R+IHA+ L                    
Sbjct: 111 HKRQRLADGQLVDTKRVLTRASAFKEGLRDLSRLIHAADLTNLKTCPKAMRVLGATEQDD 170

Query: 283 VTLGLKYPSSSNPERYALIFGND-FNPAEEIINVVRVVLDFYFPEDQAKCLKDSEKGLIR 459
           V + L+YPS   PE Y LI+  D  N  E+I+ VV+ V D Y  E QA+  +D + G IR
Sbjct: 171 VRVRLQYPSMYGPENYELIWEADKINSIEDILKVVQHVADVYLTEKQAEEFRDPDTGFIR 230

Query: 460 RLNKYYNIFARDLTDIKPLVEFKNVVEIYNSIIEKKISDGTFIRNLGSAHHIPLYMVEFI 639
           RL +     AR+  D++    FK  ++  N  I    +DGT  +NL + H +P  MV FI
Sbjct: 231 RLTR-----ARNTNDLRG---FKTALQDANRRIRALAADGTIRKNLDNMHALPRDMVHFI 282

Query: 640 LQQVYARAVSPKIEILKKYENGTDNVYGELLPPFVSKILSE-SGLKSESIFVDLGSGVGN 816
           L+QVY R VSP +E LK+Y+NGTDNVYGEL   F+S++L E + + S+ +F+DLGSGVGN
Sbjct: 283 LRQVYERTVSPNVEKLKQYKNGTDNVYGELGELFISEVLQEKTRMTSDQVFIDLGSGVGN 342

Query: 817 VVLQAALEFGCESW 858
           VV QAALE GCESW
Sbjct: 343 VVFQAALEIGCESW 356


>dbj|GAA91645.1| histone H3 methyltransferase [Aspergillus kawachii IFO 4308]
          Length = 501

 Score =  176 bits (445), Expect = 1e-41
 Identities = 102/242 (42%), Positives = 140/242 (57%), Gaps = 6/242 (2%)
 Frame = +1

Query: 151 DKKRKICLENAFSGHSASIARMIHASALVXXXXXXXXXXXXXHVVTLG---LKYPSSSNP 321
           D  R++    AFS  S     MIHA+ +                  L    L+YPS+S+P
Sbjct: 120 DPARRVRSLKAFSEDSIRSLPMIHAADITSRQKSGNFKPAFGAAKPLPELLLQYPSTSSP 179

Query: 322 ERYALIFG---NDFNPAEEIINVVRVVLDFYFPEDQAKCLKDSEKGLIRRLNKYYNIFAR 492
           ERY L+     +DF P ++I+ V+ +V   Y P+++A    +   G+ RRL +     + 
Sbjct: 180 ERYDLVVPRDHDDFKPIDDIVQVLDIVSQNYIPDEEADEFNNESTGIKRRLRRALAHSSE 239

Query: 493 DLTDIKPLVEFKNVVEIYNSIIEKKISDGTFIRNLGSAHHIPLYMVEFILQQVYARAVSP 672
                    +F+++V  YNS I +   DG+  + L S   + L  VE IL Q+Y+R VSP
Sbjct: 240 --------ADFRSIVAEYNSAIVRLRRDGSIAKKLDSTSRLNLPHVERILNQIYSRTVSP 291

Query: 673 KIEILKKYENGTDNVYGELLPPFVSKILSESGLKSESIFVDLGSGVGNVVLQAALEFGCE 852
           ++E L++YENGTDNVYGELLP F+S I  E+GLKS  +FVDLGSGVGNVVLQAALE GCE
Sbjct: 292 RVESLRQYENGTDNVYGELLPRFISTIFKETGLKSGQVFVDLGSGVGNVVLQAALEIGCE 351

Query: 853 SW 858
           SW
Sbjct: 352 SW 353


>ref|XP_003067183.1| histone-lysine N-methyltransferase, H3 lysine-79 specific, putative
           [Coccidioides posadasii C735 delta SOWgp]
           gi|240106851|gb|EER25038.1| histone-lysine
           N-methyltransferase, H3 lysine-79 specific, putative
           [Coccidioides posadasii C735 delta SOWgp]
          Length = 498

 Score =  176 bits (445), Expect = 1e-41
 Identities = 106/264 (40%), Positives = 155/264 (58%), Gaps = 8/264 (3%)
 Frame = +1

Query: 91  ENNTVIGVKSYKRRELSRFV--DKKRKICLENAFSGHSASIARMIHASALVXXXXXXXXX 264
           + +  + ++  KR  +S  V  D  R++   +AFS  +A    MIHA+ ++         
Sbjct: 97  DTDVSLDLRITKRARVSSSVEPDLHRRVRDTDAFSDEAAF--DMIHAADIISSKKSLGFN 154

Query: 265 XXXX---HVVTLGLKYPSSSNPERYALIFGND---FNPAEEIINVVRVVLDFYFPEDQAK 426
                    + + L+YP +   ERY L+   D   F P ++I+ ++ +V   Y PE+   
Sbjct: 155 NAFGIEDGPIIVELQYPGAPQKERYQLVVPRDNDGFKPLDDIVQLLEIVSQNYIPEEHLA 214

Query: 427 CLKDSEKGLIRRLNKYYNIFARDLTDIKPLVEFKNVVEIYNSIIEKKISDGTFIRNLGSA 606
             +D   GL+RRL        R L++   L +F + V+ YN  I++   DG+  R+L S 
Sbjct: 215 LFEDESNGLLRRLR-------RALSNTS-LTDFLDGVKSYNETIQRLHQDGSISRHLDSK 266

Query: 607 HHIPLYMVEFILQQVYARAVSPKIEILKKYENGTDNVYGELLPPFVSKILSESGLKSESI 786
           H + L +VE IL QVY+R VSP+++ L++YENG+DNVYGELLP  VSKI +E+ LKS+ +
Sbjct: 267 HALALPLVERILTQVYSRTVSPRVDSLRQYENGSDNVYGELLPRLVSKIFAETRLKSDQV 326

Query: 787 FVDLGSGVGNVVLQAALEFGCESW 858
           FVDLGSGVGNVVLQAALE GCESW
Sbjct: 327 FVDLGSGVGNVVLQAALEIGCESW 350


>ref|XP_003022720.1| hypothetical protein TRV_03181 [Trichophyton verrucosum HKI 0517]
           gi|291186680|gb|EFE42102.1| hypothetical protein
           TRV_03181 [Trichophyton verrucosum HKI 0517]
          Length = 522

 Score =  175 bits (444), Expect = 2e-41
 Identities = 109/265 (41%), Positives = 144/265 (54%), Gaps = 9/265 (3%)
 Frame = +1

Query: 91  ENNTVIGVKSYKRRELSRFV--DKKRKICLENAFSGHSASIARMIHASALVXXXXXXXXX 264
           E +  + ++  KR ++S     D KR++  E AFS  +     M+HA  +          
Sbjct: 117 ETDESLDIRLSKRTKVSASAEPDLKRQLRSEIAFSETAEHSFPMVHAMDIASIEKKTPGF 176

Query: 265 XXXXH----VVTLGLKYPSSSNPERYALIFGND---FNPAEEIINVVRVVLDFYFPEDQA 423
                      T+ L+YP+ S  ERY L+   +   F P E+I+ VV  V   Y PEDQ 
Sbjct: 177 SSAFKEPSGCTTIALQYPTYSQRERYQLVIPRENDGFKPLEDIVQVVETVSHNYIPEDQI 236

Query: 424 KCLKDSEKGLIRRLNKYYNIFARDLTDIKPLVEFKNVVEIYNSIIEKKISDGTFIRNLGS 603
               D   G IR L        R +    P  +F N V+ YN  I +   +G   ++L +
Sbjct: 237 SAFTDDSTGYIRLLR-------RAIKQESPK-DFWNAVKAYNETIRRLRDEGVIAKHLDA 288

Query: 604 AHHIPLYMVEFILQQVYARAVSPKIEILKKYENGTDNVYGELLPPFVSKILSESGLKSES 783
            H + L  VE IL QVY+R VS ++E LKKYENGTDNVYGELLP F+S I  ++ LKS+ 
Sbjct: 289 MHSLSLPWVERILTQVYSRTVSLRVESLKKYENGTDNVYGELLPRFISDIFQKTHLKSDQ 348

Query: 784 IFVDLGSGVGNVVLQAALEFGCESW 858
           +FVDLGSGVGNVVLQAALE GCESW
Sbjct: 349 VFVDLGSGVGNVVLQAALEVGCESW 373


>ref|XP_003044852.1| predicted protein [Nectria haematococca mpVI 77-13-4]
           gi|256725777|gb|EEU39139.1| predicted protein [Nectria
           haematococca mpVI 77-13-4]
          Length = 494

 Score =  175 bits (444), Expect = 2e-41
 Identities = 105/248 (42%), Positives = 140/248 (56%), Gaps = 10/248 (4%)
 Frame = +1

Query: 145 FVDKKRKICLENAFSG--------HSASIARMIHASALVXXXXXXXXXXXXXHVVTLGLK 300
           FVD  RK+    AF          H+  +A + H    V               V + L+
Sbjct: 125 FVDTNRKLRSVRAFKDRLDRRSFIHAVDVASLQHKCVPVMGAQKED--------VAIELQ 176

Query: 301 YPSSSNPERYALIFGND-FNPAEEIINVVRVVLDFYFPEDQAKCLKDSEKGLIRRLNKYY 477
           YPS    E+Y L++G D  +  E  I VVR V + Y  +D+A+   +   G+IRRL K  
Sbjct: 177 YPSLQPREKYELVWGKDKIDAVEASIKVVRHVAETYLTDDEAEPFTNPNGGIIRRLEKAS 236

Query: 478 NIFARDLTDIKPLVEFKNVVEIYNSIIEKKISDGTFIRNLGSAHHIPLYMVEFILQQVYA 657
           N       +I+ L+ FK  +  YN  +   + DG   +NL + H +P ++V FIL Q+Y 
Sbjct: 237 N------RNIQDLMGFKTALREYNEKLLALVEDGVISKNLDNMHELPQHLVAFILDQIYD 290

Query: 658 RAVSPKIEILKKYENGTDNVYGELLPPFVSKILSE-SGLKSESIFVDLGSGVGNVVLQAA 834
           R V+PK+E+L KYENGTD VYGELL PF+SKIL E + + S  +FVDLGSGVGNVVLQAA
Sbjct: 291 RTVAPKVELLSKYENGTDYVYGELLHPFISKILVEQTQMTSGQVFVDLGSGVGNVVLQAA 350

Query: 835 LEFGCESW 858
           LE GCESW
Sbjct: 351 LEIGCESW 358


>ref|XP_001239604.1| hypothetical protein CIMG_09225 [Coccidioides immitis RS]
           gi|121931483|sp|Q1DKD8.1|DOT1_COCIM RecName:
           Full=Histone-lysine N-methyltransferase, H3 lysine-79
           specific; AltName: Full=Histone H3-K79
           methyltransferase; Short=H3-K79-HMTase
           gi|392869804|gb|EAS28329.2| histone-lysine
           N-methyltransferase, H3 lysine-79 specific [Coccidioides
           immitis RS]
          Length = 499

 Score =  174 bits (441), Expect = 4e-41
 Identities = 106/264 (40%), Positives = 154/264 (58%), Gaps = 8/264 (3%)
 Frame = +1

Query: 91  ENNTVIGVKSYKRRELSRFV--DKKRKICLENAFSGHSASIARMIHASALVXXXXXXXXX 264
           + +  + ++  KR  +S  V  D  R++   +AFS   A+   MIHA+ ++         
Sbjct: 97  DTDVSLDLRITKRARVSSSVEPDLHRRVRDTDAFSDGEAAFD-MIHAADIISSKKSLGFN 155

Query: 265 XXXX---HVVTLGLKYPSSSNPERYALIFGND---FNPAEEIINVVRVVLDFYFPEDQAK 426
                    + + L+YP +   ERY L+   D   F P ++I+ V+ +V   Y  E+   
Sbjct: 156 NAFGIEDGPIIVELQYPGAPQKERYQLVVPRDNDGFKPLDDIVQVLEIVSQNYISEEHLA 215

Query: 427 CLKDSEKGLIRRLNKYYNIFARDLTDIKPLVEFKNVVEIYNSIIEKKISDGTFIRNLGSA 606
             +D   GL+RRL        R L++   L +F + V+ YN  I++   DG+  R+L S 
Sbjct: 216 LFEDESNGLLRRLR-------RALSNTS-LTDFLDGVKSYNETIQRLHQDGSISRHLDSK 267

Query: 607 HHIPLYMVEFILQQVYARAVSPKIEILKKYENGTDNVYGELLPPFVSKILSESGLKSESI 786
           H + L +VE IL QVY+R VSP+++ L++YENG+DNVYGELLP  VSKI +E+ LKS+ +
Sbjct: 268 HALALPLVERILTQVYSRTVSPRVDSLRQYENGSDNVYGELLPRLVSKIFAETRLKSDQV 327

Query: 787 FVDLGSGVGNVVLQAALEFGCESW 858
           FVDLGSGVGNVVLQAALE GCESW
Sbjct: 328 FVDLGSGVGNVVLQAALEIGCESW 351


>ref|XP_753440.1| conserved hypothetical protein [Aspergillus fumigatus Af293]
           gi|74673512|sp|Q4WVH4.1|DOT1_ASPFU RecName:
           Full=Histone-lysine N-methyltransferase, H3 lysine-79
           specific; AltName: Full=Histone H3-K79
           methyltransferase; Short=H3-K79-HMTase
           gi|66851076|gb|EAL91402.1| conserved hypothetical
           protein [Aspergillus fumigatus Af293]
          Length = 502

 Score =  174 bits (440), Expect = 5e-41
 Identities = 109/291 (37%), Positives = 153/291 (52%), Gaps = 6/291 (2%)
 Frame = +1

Query: 4   RLSNKLSLRKSRIVKKRPXXXXXXXXXXXENNTVIGVKSYKRRELSRFVDKKRKICLENA 183
           RLS  L  RK    +  P           + +T   ++   R E S   D  R+I    A
Sbjct: 76  RLSTPLRNRK----RPTPEQRFSSDDDASDTDTSFELRKRARTEDSAEPDLARRIRSLKA 131

Query: 184 FSGHSASIARMIHASALVXXXXXXXXXXXXXHV---VTLGLKYPSSSNPERYALIF---G 345
           FS  +     ++HA+ +                     + L+YPS+S  ER+ L+     
Sbjct: 132 FSEENVKPLPLVHAADITSKQKAGNFRRAFGGADRPTEILLQYPSASLKERFNLVVPRDN 191

Query: 346 NDFNPAEEIINVVRVVLDFYFPEDQAKCLKDSEKGLIRRLNKYYNIFARDLTDIKPLVEF 525
           +DF P ++I++V+ +V + Y PE +A    +   G+ RRL +     +          EF
Sbjct: 192 DDFKPIDDIVHVIDIVSENYIPESEADFFNNESTGIKRRLRRALAHSSE--------TEF 243

Query: 526 KNVVEIYNSIIEKKISDGTFIRNLGSAHHIPLYMVEFILQQVYARAVSPKIEILKKYENG 705
           +  V  YN  IE+    G   ++L + H + L +VE IL Q+YAR VSP++E L++YENG
Sbjct: 244 REAVASYNREIERLRRSGAIAKHLDATHRLNLPLVERILTQIYARTVSPRVESLRRYENG 303

Query: 706 TDNVYGELLPPFVSKILSESGLKSESIFVDLGSGVGNVVLQAALEFGCESW 858
           TDNVYGELLP F+S I  E+ LKS  +FVDLGSGVGNVVLQAALE GCESW
Sbjct: 304 TDNVYGELLPRFISTIFKETRLKSGHVFVDLGSGVGNVVLQAALEIGCESW 354