BLASTX 2.2.25 [Feb-01-2011]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= Mentha25_contig00026144
         (336 letters)

Database: ./nr 
           38,876,450 sequences; 13,856,398,315 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gb|AHK23089.1| auxin response factor [Dimocarpus longan]              106   4e-21
ref|XP_006481465.1| PREDICTED: auxin response factor 18-like [Ci...   101   9e-20
ref|XP_006428777.1| hypothetical protein CICLE_v10011194mg [Citr...   101   9e-20
ref|XP_004246657.1| PREDICTED: auxin response factor 18-like [So...   101   9e-20
ref|XP_006354328.1| PREDICTED: auxin response factor 18-like iso...   100   2e-19
ref|XP_006354327.1| PREDICTED: auxin response factor 18-like iso...   100   2e-19
ref|XP_007208053.1| hypothetical protein PRUPE_ppa002195mg [Prun...    98   1e-18
gb|ACI13681.1| putative auxin response factor ARF16 [Malus domes...    97   2e-18
ref|XP_004304436.1| PREDICTED: auxin response factor 18-like [Fr...    96   4e-18
ref|XP_007144353.1| hypothetical protein PHAVU_007G149000g [Phas...    95   9e-18
ref|XP_007027336.1| Auxin response factor 19 [Theobroma cacao] g...    95   9e-18
gb|EXC16214.1| Auxin response factor 18 [Morus notabilis]              95   1e-17
ref|XP_003537296.1| PREDICTED: auxin response factor 18-like iso...    91   2e-16
ref|XP_002519531.1| Auxin response factor, putative [Ricinus com...    89   5e-16
gb|EYU34460.1| hypothetical protein MIMGU_mgv1a002753mg [Mimulus...    87   2e-15
ref|XP_006604575.1| PREDICTED: auxin response factor 18-like [Gl...    87   2e-15
ref|XP_004497510.1| PREDICTED: auxin response factor 18-like [Ci...    86   5e-15
ref|XP_002281486.1| PREDICTED: auxin response factor 18-like [Vi...    83   3e-14
gb|AGQ53958.1| auxin response factor 10b [Cucumis sativus]             82   6e-14
ref|XP_004156337.1| PREDICTED: auxin response factor 18-like [Cu...    82   6e-14

>gb|AHK23089.1| auxin response factor [Dimocarpus longan]
          Length = 699

 Score =  106 bits (264), Expect = 4e-21
 Identities = 53/106 (50%), Positives = 66/106 (62%), Gaps = 3/106 (2%)
 Frame = -3

Query: 334 FPFDGQIPLPPFPHQLMGSSNPFGCVPNSNTPAGMQGARHAQYGXXXXXXXXXXXXXXLF 155
           FP DGQ+P+P FP  L+G ++PFGC+P+ NTPAGMQGARHA YG               F
Sbjct: 420 FPLDGQLPMPTFPGNLLGHNSPFGCLPD-NTPAGMQGARHAHYGLSLSDHHLNKLQSGPF 478

Query: 154 PLGFLPLDRV---PTGPSTPHLPKPGSSENISCLLTIGNPTQGSNK 26
             GF+PLDR        S+P + KP  SEN+SCLLT+ + TQ S K
Sbjct: 479 SAGFVPLDRAAPPKRASSSPIIQKPSMSENVSCLLTMAHSTQTSKK 524


>ref|XP_006481465.1| PREDICTED: auxin response factor 18-like [Citrus sinensis]
          Length = 703

 Score =  101 bits (252), Expect = 9e-20
 Identities = 56/106 (52%), Positives = 66/106 (62%), Gaps = 3/106 (2%)
 Frame = -3

Query: 334 FPFDGQIPLPPFPHQLMGSSNPFGCVPNSNTPAGMQGARHAQYGXXXXXXXXXXXXXXLF 155
           FP DGQ+P+P F   L+G ++PFGC+P+ NTPAGMQGARHA YG              L 
Sbjct: 424 FPLDGQLPMPSFSGSLLGPNSPFGCLPD-NTPAGMQGARHAHYGLSLSDLHLNKLQSGLS 482

Query: 154 PLGFLPLDRV--PTGPS-TPHLPKPGSSENISCLLTIGNPTQGSNK 26
           P GF P DR   PT  S +P L KP  SENISCLLT+ + TQ S K
Sbjct: 483 PAGFPPFDRAAKPTRASNSPILQKPSMSENISCLLTMSHSTQPSKK 528


>ref|XP_006428777.1| hypothetical protein CICLE_v10011194mg [Citrus clementina]
           gi|557530834|gb|ESR42017.1| hypothetical protein
           CICLE_v10011194mg [Citrus clementina]
          Length = 703

 Score =  101 bits (252), Expect = 9e-20
 Identities = 56/106 (52%), Positives = 66/106 (62%), Gaps = 3/106 (2%)
 Frame = -3

Query: 334 FPFDGQIPLPPFPHQLMGSSNPFGCVPNSNTPAGMQGARHAQYGXXXXXXXXXXXXXXLF 155
           FP DGQ+P+P F   L+G ++PFGC+P+ NTPAGMQGARHA YG              L 
Sbjct: 424 FPLDGQLPMPSFSGSLLGPNSPFGCLPD-NTPAGMQGARHAHYGLSLSDLHLNKLQSGLS 482

Query: 154 PLGFLPLDRV--PTGPS-TPHLPKPGSSENISCLLTIGNPTQGSNK 26
           P GF P DR   PT  S +P L KP  SENISCLLT+ + TQ S K
Sbjct: 483 PAGFPPFDRAAKPTRASNSPILQKPSMSENISCLLTMSHSTQPSKK 528


>ref|XP_004246657.1| PREDICTED: auxin response factor 18-like [Solanum lycopersicum]
          Length = 694

 Score =  101 bits (252), Expect = 9e-20
 Identities = 52/108 (48%), Positives = 69/108 (63%), Gaps = 5/108 (4%)
 Frame = -3

Query: 334 FPFDGQIPLPPFP-HQLMGSSNPFGCVPNSNTPAGMQGARHAQYGXXXXXXXXXXXXXXL 158
           FP DG +P+P F  + L+G ++PFGC+P+ NTPAGMQGARHAQYG              L
Sbjct: 419 FPLDGHLPMPAFSGNHLLGPNSPFGCLPD-NTPAGMQGARHAQYGLSLSDLHFNKLHSSL 477

Query: 157 FPLGFLPLDRVPTGP----STPHLPKPGSSENISCLLTIGNPTQGSNK 26
           FP+GF PLD+    P    ++P + KP ++ENISCLLT+GN    + K
Sbjct: 478 FPVGFPPLDQAAAAPRRPLNSPMISKPCNNENISCLLTMGNSAHSTKK 525


>ref|XP_006354328.1| PREDICTED: auxin response factor 18-like isoform X2 [Solanum
           tuberosum]
          Length = 610

 Score =  100 bits (250), Expect = 2e-19
 Identities = 52/108 (48%), Positives = 68/108 (62%), Gaps = 5/108 (4%)
 Frame = -3

Query: 334 FPFDGQIPLPPFP-HQLMGSSNPFGCVPNSNTPAGMQGARHAQYGXXXXXXXXXXXXXXL 158
           FP DG +P+P F  + L+G ++PFGC+P+ NTPAGMQGARHAQYG              L
Sbjct: 421 FPLDGHLPMPAFSGNHLLGPNSPFGCLPD-NTPAGMQGARHAQYGLSLSDLHFNKLHSSL 479

Query: 157 FPLGFLPLDRVPTGP----STPHLPKPGSSENISCLLTIGNPTQGSNK 26
           FP+GF PLD+    P    + P + KP ++ENISCLLT+GN    + K
Sbjct: 480 FPVGFPPLDQAAAAPRRPLNIPMISKPCNNENISCLLTMGNSAHSTKK 527


>ref|XP_006354327.1| PREDICTED: auxin response factor 18-like isoform X1 [Solanum
           tuberosum]
          Length = 696

 Score =  100 bits (250), Expect = 2e-19
 Identities = 52/108 (48%), Positives = 68/108 (62%), Gaps = 5/108 (4%)
 Frame = -3

Query: 334 FPFDGQIPLPPFP-HQLMGSSNPFGCVPNSNTPAGMQGARHAQYGXXXXXXXXXXXXXXL 158
           FP DG +P+P F  + L+G ++PFGC+P+ NTPAGMQGARHAQYG              L
Sbjct: 421 FPLDGHLPMPAFSGNHLLGPNSPFGCLPD-NTPAGMQGARHAQYGLSLSDLHFNKLHSSL 479

Query: 157 FPLGFLPLDRVPTGP----STPHLPKPGSSENISCLLTIGNPTQGSNK 26
           FP+GF PLD+    P    + P + KP ++ENISCLLT+GN    + K
Sbjct: 480 FPVGFPPLDQAAAAPRRPLNIPMISKPCNNENISCLLTMGNSAHSTKK 527


>ref|XP_007208053.1| hypothetical protein PRUPE_ppa002195mg [Prunus persica]
           gi|462403695|gb|EMJ09252.1| hypothetical protein
           PRUPE_ppa002195mg [Prunus persica]
          Length = 703

 Score = 97.8 bits (242), Expect = 1e-18
 Identities = 51/106 (48%), Positives = 62/106 (58%), Gaps = 3/106 (2%)
 Frame = -3

Query: 334 FPFDGQIPLPPFPHQLMGSSNPFGCVPNSNTPAGMQGARHAQYGXXXXXXXXXXXXXXLF 155
           FPF+GQ+P+P F   L+G S+PFGC+P+  TPAGMQGARH  YG              LF
Sbjct: 422 FPFEGQLPMPTFSGNLLGPSSPFGCLPD-KTPAGMQGARHGHYGLSLSDMHLNKLQTGLF 480

Query: 154 PLGFLPLDRVPTG---PSTPHLPKPGSSENISCLLTIGNPTQGSNK 26
           P GF PLD   T     +     KP  SEN+SCLLT+ + TQ S K
Sbjct: 481 PAGFTPLDHAATATKFSNNTMTQKPTMSENVSCLLTMAHSTQTSKK 526


>gb|ACI13681.1| putative auxin response factor ARF16 [Malus domestica]
          Length = 702

 Score = 97.1 bits (240), Expect = 2e-18
 Identities = 53/107 (49%), Positives = 64/107 (59%), Gaps = 4/107 (3%)
 Frame = -3

Query: 334 FPFDGQIPLPPFPHQLMGSSNPFGCVPNSNTPAGMQGARHAQYGXXXXXXXXXXXXXXLF 155
           FPF+GQ+P+P F   L+G S+PFGC+P+  TPAGMQGARHA YG              LF
Sbjct: 422 FPFEGQLPMPTFSGNLLGPSSPFGCLPD-KTPAGMQGARHAHYGLSLSDMHLNKLHTGLF 480

Query: 154 PLGFLPLDRVPTGPS----TPHLPKPGSSENISCLLTIGNPTQGSNK 26
           P GF PLD     PS       + KP  SEN+SCLLT+ + TQ S K
Sbjct: 481 PAGFPPLDHA-AAPSKFSNNTMIQKPTMSENLSCLLTMSHSTQTSKK 526


>ref|XP_004304436.1| PREDICTED: auxin response factor 18-like [Fragaria vesca subsp.
           vesca]
          Length = 731

 Score = 96.3 bits (238), Expect = 4e-18
 Identities = 51/108 (47%), Positives = 66/108 (61%), Gaps = 5/108 (4%)
 Frame = -3

Query: 334 FPFDGQIPLPPFP--HQLMGSSNPFGCVPNSNTPAGMQGARHAQYGXXXXXXXXXXXXXX 161
           FPF+GQ+P+P F   H L+G+S+PFGC+P+  TPAGMQGARHA YG              
Sbjct: 450 FPFEGQLPMPTFSGNHHLLGTSSPFGCLPDK-TPAGMQGARHAHYGLSLSDIHLNKLQSG 508

Query: 160 LFPLGFLPLDRVPTG---PSTPHLPKPGSSENISCLLTIGNPTQGSNK 26
           LFP GF PLD V T     +   + +P  SEN+SCLLT+ +  Q + K
Sbjct: 509 LFPAGFPPLDHVATPTKFSNNTMIQRPTMSENVSCLLTMSHSPQSTKK 556


>ref|XP_007144353.1| hypothetical protein PHAVU_007G149000g [Phaseolus vulgaris]
           gi|561017543|gb|ESW16347.1| hypothetical protein
           PHAVU_007G149000g [Phaseolus vulgaris]
          Length = 708

 Score = 95.1 bits (235), Expect = 9e-18
 Identities = 56/114 (49%), Positives = 64/114 (56%), Gaps = 5/114 (4%)
 Frame = -3

Query: 334 FPFDGQIPLPPFPHQLMGSSNP--FGCVPNSNTPAGMQGARHAQYGXXXXXXXXXXXXXX 161
           FP DGQI LP F   L+G SN   FGC+P S TPAGMQGARHA YG              
Sbjct: 418 FPLDGQIHLPTFSGNLLGPSNTNQFGCLPES-TPAGMQGARHAHYGLSISDLHFSKLHSG 476

Query: 160 LFPLGFLPLDRVPTGPSTPH---LPKPGSSENISCLLTIGNPTQGSNKLPNSEK 8
           LFP GF PLD   T     +   L KP  SEN+SCLL++ N TQ S K+   +K
Sbjct: 477 LFPAGFPPLDHAATPMRISNNLTLQKPTISENVSCLLSMANSTQSSKKMDEGKK 530


>ref|XP_007027336.1| Auxin response factor 19 [Theobroma cacao]
           gi|508715941|gb|EOY07838.1| Auxin response factor 19
           [Theobroma cacao]
          Length = 709

 Score = 95.1 bits (235), Expect = 9e-18
 Identities = 50/112 (44%), Positives = 65/112 (58%), Gaps = 4/112 (3%)
 Frame = -3

Query: 334 FPFDGQIPLPPFPHQLMGSSNPFGCVPNSNTPAGMQGARHAQYGXXXXXXXXXXXXXXLF 155
           FP D Q+P+P F   L+G S+PFGC+P+ +TPAGMQGARHA YG              LF
Sbjct: 422 FPLDSQLPMPTFSGNLLGPSSPFGCLPD-HTPAGMQGARHAYYGLSLSDLHLKKLQSGLF 480

Query: 154 PLGFLPLDRVPTGPST----PHLPKPGSSENISCLLTIGNPTQGSNKLPNSE 11
           P GF P D   T   T    P + KP  SEN+SC+LT+ + TQ   K  +++
Sbjct: 481 PAGFPPPDHAATPNRTSNGGPIIQKPSMSENVSCVLTMAHSTQNCKKTDDAK 532


>gb|EXC16214.1| Auxin response factor 18 [Morus notabilis]
          Length = 691

 Score = 94.7 bits (234), Expect = 1e-17
 Identities = 51/106 (48%), Positives = 60/106 (56%), Gaps = 3/106 (2%)
 Frame = -3

Query: 334 FPFDGQIPLPPFPHQLMGSSNPFGCVPNSNTPAGMQGARHAQYGXXXXXXXXXXXXXXLF 155
           FPFDG IP+P F   L+G SNPFGC+ + NTPAGMQGARHA YG              LF
Sbjct: 412 FPFDGHIPIPTFSGNLLGHSNPFGCL-SENTPAGMQGARHAHYGLSISDLHLNKLQSGLF 470

Query: 154 PLGFLPLDRVPTG---PSTPHLPKPGSSENISCLLTIGNPTQGSNK 26
           P+GF P D V       S     KP  +E +SCLLT+ + TQ   K
Sbjct: 471 PVGFPPFDHVAAATKFSSNTMNYKPNLNEKVSCLLTMAHATQAPKK 516


>ref|XP_003537296.1| PREDICTED: auxin response factor 18-like isoform X1 [Glycine max]
           gi|571481827|ref|XP_006588784.1| PREDICTED: auxin
           response factor 18-like isoform X2 [Glycine max]
          Length = 700

 Score = 90.5 bits (223), Expect = 2e-16
 Identities = 55/109 (50%), Positives = 60/109 (55%), Gaps = 5/109 (4%)
 Frame = -3

Query: 334 FPFDGQIPLPPFPHQLMGSSNP--FGCVPNSNTPAGMQGARHAQYGXXXXXXXXXXXXXX 161
           FP DGQIPL  FP  L+G SN   FGC+  S TPAGMQGARHA YG              
Sbjct: 419 FPLDGQIPLSTFPSNLLGPSNTNQFGCLLES-TPAGMQGARHAHYGLSLSDLHLSKLQSG 477

Query: 160 LFPLGFLPLDRVPTGPSTPH---LPKPGSSENISCLLTIGNPTQGSNKL 23
           LF  GF  LD   T     +   L KP  SEN+SCLLT+ N TQ S KL
Sbjct: 478 LFSTGFPSLDHAATPMRVSNSITLQKPNLSENVSCLLTMANSTQSSKKL 526


>ref|XP_002519531.1| Auxin response factor, putative [Ricinus communis]
           gi|223541394|gb|EEF42945.1| Auxin response factor,
           putative [Ricinus communis]
          Length = 702

 Score = 89.4 bits (220), Expect = 5e-16
 Identities = 51/110 (46%), Positives = 62/110 (56%), Gaps = 4/110 (3%)
 Frame = -3

Query: 334 FPFDGQIPLPPFPHQLMGSSNPFGCVPNSNTPAGMQGARHAQYGXXXXXXXXXXXXXXLF 155
           FP D Q PLP F   L+G ++PFGC+P+ NTPAGMQGARHA YG              LF
Sbjct: 422 FPLDSQFPLPTFSGNLLGPTSPFGCLPD-NTPAGMQGARHAHYGLPLSDLRLNKLQTSLF 480

Query: 154 PLGF-LPLDRVPT---GPSTPHLPKPGSSENISCLLTIGNPTQGSNKLPN 17
             GF  PLD   T     + P + KP  SE++SC+LT+   TQ S K  N
Sbjct: 481 LAGFPPPLDHSATHSISSNGPTIVKPSMSESVSCVLTMARSTQNSGKPDN 530


>gb|EYU34460.1| hypothetical protein MIMGU_mgv1a002753mg [Mimulus guttatus]
          Length = 641

 Score = 87.0 bits (214), Expect = 2e-15
 Identities = 54/112 (48%), Positives = 64/112 (57%), Gaps = 3/112 (2%)
 Frame = -3

Query: 331 PFDGQIPLPPFPHQLMGSSNPFGCVPNSN---TPAGMQGARHAQYGXXXXXXXXXXXXXX 161
           PFDGQIPLP F      S NPFGC+PN+N   TPAGMQGARH                  
Sbjct: 413 PFDGQIPLPAF------SGNPFGCLPNNNNNNTPAGMQGARHG------------LSLSD 454

Query: 160 LFPLGFLPLDRVPTGPSTPHLPKPGSSENISCLLTIGNPTQGSNKLPNSEKA 5
           LFP GF+PL+RVP  PST       ++EN+SC LT+GN  +GS    N + A
Sbjct: 455 LFPAGFMPLNRVPL-PST-----TANNENVSCQLTMGNSNRGSKVSDNCKTA 500


>ref|XP_006604575.1| PREDICTED: auxin response factor 18-like [Glycine max]
          Length = 700

 Score = 87.0 bits (214), Expect = 2e-15
 Identities = 48/110 (43%), Positives = 60/110 (54%), Gaps = 6/110 (5%)
 Frame = -3

Query: 334 FPFDGQIPLPPFPHQLMGSSNPFGCVPNSNTPAGMQGARHAQYGXXXXXXXXXXXXXXLF 155
           F FDGQI LP FP   +G SNPFGC+  S TPAG+QGARHA YG              LF
Sbjct: 425 FSFDGQISLPAFPSNFLGPSNPFGCLAES-TPAGIQGARHANYGISLSNLHFNKLQSGLF 483

Query: 154 PLGFLPLDRVP------TGPSTPHLPKPGSSENISCLLTIGNPTQGSNKL 23
             GF PLD         +  +   + K G+ +N+SCLL++   TQ S K+
Sbjct: 484 QAGFPPLDHTASPVLRVSSNNAATMQKVGTGDNVSCLLSMSTATQPSKKV 533


>ref|XP_004497510.1| PREDICTED: auxin response factor 18-like [Cicer arietinum]
          Length = 692

 Score = 85.9 bits (211), Expect = 5e-15
 Identities = 51/113 (45%), Positives = 62/113 (54%), Gaps = 4/113 (3%)
 Frame = -3

Query: 334 FPFDGQIPLPP-FPHQLMGSSNPFGCVPNSNTPAGMQGARHAQYGXXXXXXXXXXXXXXL 158
           FP DGQI +PP FP  L+  +N FG +P S TPAGMQGARHA YG              L
Sbjct: 428 FPLDGQISMPPTFPSNLLDPNNLFGRLPES-TPAGMQGARHAHYGRPISDFHLSKVQSGL 486

Query: 157 FPLGFLPLDRVPTGPSTPH---LPKPGSSENISCLLTIGNPTQGSNKLPNSEK 8
           F  GFLP D   T  S  +   L K   SEN+SCLL++ +  Q S K  + +K
Sbjct: 487 FSAGFLPFDHAATPHSVSNNLMLQKSSVSENVSCLLSMASSNQSSTKFNDEKK 539


>ref|XP_002281486.1| PREDICTED: auxin response factor 18-like [Vitis vinifera]
          Length = 701

 Score = 83.2 bits (204), Expect = 3e-14
 Identities = 49/106 (46%), Positives = 56/106 (52%), Gaps = 3/106 (2%)
 Frame = -3

Query: 334 FPFDGQIPLPPFPHQLMGSSNPFGCVPNSNTPAGMQGARHAQYGXXXXXXXXXXXXXXLF 155
           FP D Q  +P F   L+G SNPFGC+ + N PAGMQGARHAQYG              LF
Sbjct: 420 FPLDAQFSMPTFSSNLVGPSNPFGCL-SDNIPAGMQGARHAQYGLSLSDPHHNKFQSGLF 478

Query: 154 PLGFLPLDRVPTGPSTPH---LPKPGSSENISCLLTIGNPTQGSNK 26
           P  F  LD   T P   +     K  SSEN+S LLTI   T+ S K
Sbjct: 479 PAPFPQLDHPATPPKASNDYVSRKRSSSENVSSLLTIAQSTETSKK 524


>gb|AGQ53958.1| auxin response factor 10b [Cucumis sativus]
          Length = 694

 Score = 82.4 bits (202), Expect = 6e-14
 Identities = 48/108 (44%), Positives = 59/108 (54%), Gaps = 5/108 (4%)
 Frame = -3

Query: 334 FPFDGQIPLPPFPHQLMGSSNPFGCVPNSNTPAGMQGARHAQYGXXXXXXXXXXXXXXLF 155
           FP D Q P+P F   L G+ +PFGC P++N PAGMQGARHA +G              LF
Sbjct: 415 FPLDNQPPVPSFSSYLHGTGSPFGCPPDNN-PAGMQGARHAHFGLSLSDFHVSKLQSGLF 473

Query: 154 PLGFLPLDRVPTGPST-----PHLPKPGSSENISCLLTIGNPTQGSNK 26
            +G+  LD  P   ST         KP  SEN+SCLLT+ + TQ S K
Sbjct: 474 SIGYRSLD--PAAGSTRLSGNVMTEKPSMSENVSCLLTMAHSTQASKK 519


>ref|XP_004156337.1| PREDICTED: auxin response factor 18-like [Cucumis sativus]
          Length = 701

 Score = 82.4 bits (202), Expect = 6e-14
 Identities = 48/108 (44%), Positives = 59/108 (54%), Gaps = 5/108 (4%)
 Frame = -3

Query: 334 FPFDGQIPLPPFPHQLMGSSNPFGCVPNSNTPAGMQGARHAQYGXXXXXXXXXXXXXXLF 155
           FP D Q P+P F   L G+ +PFGC P++N PAGMQGARHA +G              LF
Sbjct: 419 FPLDNQPPVPSFSSYLHGTGSPFGCPPDNN-PAGMQGARHAHFGLSLSDFHVSKLQSGLF 477

Query: 154 PLGFLPLDRVPTGPST-----PHLPKPGSSENISCLLTIGNPTQGSNK 26
            +G+  LD  P   ST         KP  SEN+SCLLT+ + TQ S K
Sbjct: 478 SIGYRSLD--PAAGSTRLSGNVMTEKPSMSENVSCLLTMAHSTQASKK 523