BLASTX nr result
ID: Mentha24_contig00033342
seq
BLASTX 2.2.25 [Feb-01-2011]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Mentha24_contig00033342
(419 letters)
Database: ./nr
38,876,450 sequences; 13,856,398,315 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gb|EYU27303.1| hypothetical protein MIMGU_mgv1a026892mg [Mimulus... 172 6e-41
ref|XP_006346555.1| PREDICTED: uncharacterized protein LOC102592... 119 4e-25
gb|EYU20505.1| hypothetical protein MIMGU_mgv1a024584mg [Mimulus... 116 4e-24
gb|EYU20509.1| hypothetical protein MIMGU_mgv1a018255mg [Mimulus... 115 5e-24
ref|XP_004242947.1| PREDICTED: cytidine deaminase-like [Solanum ... 110 2e-22
gb|AAD30449.1|AF121878_1 cytidine deaminase [Arabidopsis thaliana] 98 1e-18
ref|XP_006371993.1| cytidine deaminase 1 family protein [Populus... 98 1e-18
gb|EXB38831.1| Cytidine deaminase [Morus notabilis] 97 3e-18
ref|NP_179547.1| cytidine deaminase 1 [Arabidopsis thaliana] gi|... 92 7e-17
ref|XP_007160233.1| hypothetical protein PHAVU_002G304000g [Phas... 92 7e-17
gb|AAF03356.1|AF134485_1 cytidine deaminase 1 [Arabidopsis thali... 92 7e-17
gb|AAF03357.1|AF134486_1 cytidine deaminase 1, partial [Arabidop... 92 7e-17
ref|XP_002514140.1| cytidine deaminase 1, 2, 7, putative [Ricinu... 92 7e-17
gb|AAM62679.1| putative cytidine deaminase [Arabidopsis thaliana] 92 7e-17
ref|XP_007012863.1| Cytidine deaminase [Theobroma cacao] gi|5087... 92 1e-16
ref|XP_002308296.1| cytidine deaminase 1 family protein [Populus... 90 4e-16
ref|XP_006298210.1| hypothetical protein CARUB_v10014260mg [Caps... 89 5e-16
gb|AFK48519.1| unknown [Lotus japonicus] 88 1e-15
ref|XP_002883984.1| hypothetical protein ARALYDRAFT_480515 [Arab... 88 1e-15
ref|XP_004287542.1| PREDICTED: cytidine deaminase-like [Fragaria... 88 1e-15
>gb|EYU27303.1| hypothetical protein MIMGU_mgv1a026892mg [Mimulus guttatus]
Length = 324
Score = 172 bits (435), Expect = 6e-41
Identities = 88/140 (62%), Positives = 104/140 (74%), Gaps = 1/140 (0%)
Frame = +2
Query: 2 HRCPSLLAVAVSAAPCGHCRQFYQELRHSASLQILITDEDNCVQNHDRIGMLENKAPDFM 181
HRC LL+ AVS+APCGHCRQF QELRHS+S+QIL+ DE+NC QN D + EN+
Sbjct: 95 HRCRRLLSFAVSSAPCGHCRQFLQELRHSSSVQILVIDEENCAQNIDHV---ENR----K 147
Query: 182 PLLKFLPHPFGPHDLLDQETPLMLEQHDNRLDLLHQDDSDTDTSSANLCNGND-NSGKFS 358
PL KFLP+PFGPHDLLD E PL+L+QHDNRLDLL +S NL NGND N K +
Sbjct: 148 PLSKFLPNPFGPHDLLDHECPLLLDQHDNRLDLL----PPNTVNSVNLSNGNDENFSKLA 203
Query: 359 NGDCGKHEKGESLLREAALE 418
NG+CGK+EK E LLRE+ALE
Sbjct: 204 NGNCGKYEKSEDLLRESALE 223
>ref|XP_006346555.1| PREDICTED: uncharacterized protein LOC102592443 [Solanum tuberosum]
Length = 324
Score = 119 bits (298), Expect = 4e-25
Identities = 72/143 (50%), Positives = 88/143 (61%), Gaps = 4/143 (2%)
Frame = +2
Query: 2 HRCPSLLAVAVSAAPCGHCRQFYQELRHSASLQILITDEDNCVQNHDRIGMLENKAPDFM 181
HRCP L+A AVSAAPCGHCRQF QELR+ + LQI IT + QN+ + F
Sbjct: 90 HRCPRLVAFAVSAAPCGHCRQFLQELRNPSDLQIHITSQH---QNNPNV--------TFE 138
Query: 182 PLLKFLPHPFGPHDLLDQETPLMLEQHDNRLDLLHQDDSDTDTSSANLCNGNDN----SG 349
PL + LP+PFGP DLLD ETPL+LE+H+N L L ++ + D D LCNG + SG
Sbjct: 139 PLREILPNPFGPFDLLDDETPLLLERHNNGLILSYEINHDGD-----LCNGFSDDDLKSG 193
Query: 350 KFSNGDCGKHEKGESLLREAALE 418
SNG E +LLR AALE
Sbjct: 194 NLSNGFYKLTETESTLLRIAALE 216
>gb|EYU20505.1| hypothetical protein MIMGU_mgv1a024584mg [Mimulus guttatus]
Length = 269
Score = 116 bits (290), Expect = 4e-24
Identities = 58/94 (61%), Positives = 70/94 (74%)
Frame = +2
Query: 2 HRCPSLLAVAVSAAPCGHCRQFYQELRHSASLQILITDEDNCVQNHDRIGMLENKAPDFM 181
HRC LL+ AVS+APCGH R+F QELRH +S+QIL+ +E+NC QN D + EN+
Sbjct: 95 HRCRRLLSFAVSSAPCGHFREFLQELRHCSSVQILVINEENCAQNIDHV---ENR----K 147
Query: 182 PLLKFLPHPFGPHDLLDQETPLMLEQHDNRLDLL 283
PL KFLP+PFGPHDLLD E L+L QHDN LDLL
Sbjct: 148 PLSKFLPNPFGPHDLLDHECWLLLNQHDNWLDLL 181
>gb|EYU20509.1| hypothetical protein MIMGU_mgv1a018255mg [Mimulus guttatus]
Length = 269
Score = 115 bits (289), Expect = 5e-24
Identities = 58/94 (61%), Positives = 70/94 (74%)
Frame = +2
Query: 2 HRCPSLLAVAVSAAPCGHCRQFYQELRHSASLQILITDEDNCVQNHDRIGMLENKAPDFM 181
HRC LL+ AVS+APCGH R+F QELRH +S+QIL+ +E+NC QN D + EN+
Sbjct: 95 HRCRRLLSFAVSSAPCGHFRKFLQELRHCSSVQILVINEENCAQNIDHV---ENR----K 147
Query: 182 PLLKFLPHPFGPHDLLDQETPLMLEQHDNRLDLL 283
PL KFLP+PFGPHDLLD E L+L QHDN LDLL
Sbjct: 148 PLSKFLPNPFGPHDLLDHECWLLLNQHDNWLDLL 181
>ref|XP_004242947.1| PREDICTED: cytidine deaminase-like [Solanum lycopersicum]
Length = 326
Score = 110 bits (275), Expect = 2e-22
Identities = 72/143 (50%), Positives = 86/143 (60%), Gaps = 5/143 (3%)
Frame = +2
Query: 2 HRCPSLLAVAVSAAPCGHCRQFYQELRHSASLQILITDEDNCVQNHDRIGMLENKAPDFM 181
H CP L+A AVSAAPCGHCRQF QELR+S+ LQI IT + N D I F
Sbjct: 90 HLCPRLVAFAVSAAPCGHCRQFLQELRNSSDLQIHITSQHQ--NNPDVI---------FE 138
Query: 182 PLLKFLPHPFGPHDLLDQETPLMLEQHDNRLDLLHQDDSDTDTSSANLCNGNDN----SG 349
PL + LP+PFGP DLLD ETPL+LE+H+N L L ++ + D LCNG + SG
Sbjct: 139 PLREILPNPFGPFDLLDDETPLLLERHNNNLILSYEINHVGD-----LCNGFSDDDLKSG 193
Query: 350 K-FSNGDCGKHEKGESLLREAAL 415
K SNG E +LLR AAL
Sbjct: 194 KNLSNGFYKLTETESTLLRIAAL 216
>gb|AAD30449.1|AF121878_1 cytidine deaminase [Arabidopsis thaliana]
Length = 304
Score = 98.2 bits (243), Expect = 1e-18
Identities = 54/110 (49%), Positives = 70/110 (63%), Gaps = 1/110 (0%)
Frame = +2
Query: 29 AVSAAPCGHCRQFYQELRHSASLQILITDEDNCVQNHDRIGMLENKAPDFMPLLKFLPHP 208
AVSAAPCGHCRQF QE+R + ++ILITD +N + + F+ L FLPH
Sbjct: 98 AVSAAPCGHCRQFLQEIRDAPEIKILITDPNNSADSDSDSAA---DSDGFLALGSFLPHR 154
Query: 209 FGPHDLLDQETPLMLEQHDNRLDLLHQDDSDTDTSSANLCNGN-DNSGKF 355
FGP DLL ++TPL+LE HDN L + SD D ++CNGN D+SG+F
Sbjct: 155 FGPDDLLGKDTPLLLESHDNHLKI-----SDLD----SICNGNTDSSGRF 195
>ref|XP_006371993.1| cytidine deaminase 1 family protein [Populus trichocarpa]
gi|550318239|gb|ERP49790.1| cytidine deaminase 1 family
protein [Populus trichocarpa]
Length = 314
Score = 97.8 bits (242), Expect = 1e-18
Identities = 52/103 (50%), Positives = 64/103 (62%)
Frame = +2
Query: 11 PSLLAVAVSAAPCGHCRQFYQELRHSASLQILITDEDNCVQNHDRIGMLENKAPDFMPLL 190
PSL VAVSAAPCGHCRQF+QE+RH+ + ILIT + N NH+ L N+ F P+
Sbjct: 92 PSLKYVAVSAAPCGHCRQFFQEIRHAPDIHILITGDSN--SNHNYKNDLANE-EQFEPMS 148
Query: 191 KFLPHPFGPHDLLDQETPLMLEQHDNRLDLLHQDDSDTDTSSA 319
LPH FGP DLL ++ PL+LE H N L L D S+A
Sbjct: 149 CLLPHRFGPDDLLGKDVPLLLEPHHNNLSFLGDDKLPYGVSAA 191
>gb|EXB38831.1| Cytidine deaminase [Morus notabilis]
Length = 307
Score = 96.7 bits (239), Expect = 3e-18
Identities = 52/116 (44%), Positives = 68/116 (58%)
Frame = +2
Query: 2 HRCPSLLAVAVSAAPCGHCRQFYQELRHSASLQILITDEDNCVQNHDRIGMLENKAPDFM 181
H P L + AVS+APCGHCRQF QELR + +++ILIT+ D ++ DF
Sbjct: 90 HSEPHLDSFAVSSAPCGHCRQFLQELRGAPAIKILITEPDGGCRS------------DFE 137
Query: 182 PLLKFLPHPFGPHDLLDQETPLMLEQHDNRLDLLHQDDSDTDTSSANLCNGNDNSG 349
PLL LPH FGP DLL ++ PL+LE HDNRL+ + + LCNG +G
Sbjct: 138 PLLSLLPHRFGPDDLLSRDVPLLLEPHDNRLEFPIE-------AGGGLCNGGGENG 186
>ref|NP_179547.1| cytidine deaminase 1 [Arabidopsis thaliana]
gi|6090835|gb|AAF03358.1|AF134487_1 cytidine deaminase 1
[Arabidopsis thaliana] gi|3046700|emb|CAA06460.1|
cytidine deaminase [Arabidopsis thaliana]
gi|3093276|emb|CAA06671.1| cytidine deaminase
[Arabidopsis thaliana] gi|4191787|gb|AAD10156.1|
putative cytidine deaminase [Arabidopsis thaliana]
gi|22135974|gb|AAM91569.1| putative cytidine deaminase
[Arabidopsis thaliana] gi|30984516|gb|AAP42721.1|
At2g19570 [Arabidopsis thaliana]
gi|330251802|gb|AEC06896.1| cytidine deaminase 1
[Arabidopsis thaliana]
Length = 301
Score = 92.0 bits (227), Expect = 7e-17
Identities = 50/106 (47%), Positives = 65/106 (61%)
Frame = +2
Query: 29 AVSAAPCGHCRQFYQELRHSASLQILITDEDNCVQNHDRIGMLENKAPDFMPLLKFLPHP 208
AVSAAPCGHCRQF QE+R + ++ILITD +N + + F+ L FLPH
Sbjct: 98 AVSAAPCGHCRQFLQEIRDAPEIKILITDPNNSADSDSAA-----DSDGFLRLGSFLPHR 152
Query: 209 FGPHDLLDQETPLMLEQHDNRLDLLHQDDSDTDTSSANLCNGNDNS 346
FGP DLL ++ PL+LE HDN L + SD D ++CNGN +S
Sbjct: 153 FGPDDLLGKDHPLLLESHDNHLKI-----SDLD----SICNGNTDS 189
>ref|XP_007160233.1| hypothetical protein PHAVU_002G304000g [Phaseolus vulgaris]
gi|561033648|gb|ESW32227.1| hypothetical protein
PHAVU_002G304000g [Phaseolus vulgaris]
Length = 324
Score = 92.0 bits (227), Expect = 7e-17
Identities = 52/116 (44%), Positives = 65/116 (56%)
Frame = +2
Query: 14 SLLAVAVSAAPCGHCRQFYQELRHSASLQILITDEDNCVQNHDRIGMLENKAPDFMPLLK 193
+L + AVSAAPCGHCRQF QELR ++ + IL+T + P F PL
Sbjct: 119 NLASFAVSAAPCGHCRQFLQELRAASDVNILVTS---------------HATPQFTPLSD 163
Query: 194 FLPHPFGPHDLLDQETPLMLEQHDNRLDLLHQDDSDTDTSSANLCNGNDNSGKFSN 361
FLPH FGPHDLL TPL+LE H N L LL + + A L NG+ ++ K N
Sbjct: 164 FLPHQFGPHDLLSLRTPLLLEPHHNALTLLPSHAA----NDAALSNGHLHNHKLKN 215
>gb|AAF03356.1|AF134485_1 cytidine deaminase 1 [Arabidopsis thaliana]
Length = 288
Score = 92.0 bits (227), Expect = 7e-17
Identities = 50/106 (47%), Positives = 65/106 (61%)
Frame = +2
Query: 29 AVSAAPCGHCRQFYQELRHSASLQILITDEDNCVQNHDRIGMLENKAPDFMPLLKFLPHP 208
AVSAAPCGHCRQF QE+R + ++ILITD +N + + F+ L FLPH
Sbjct: 98 AVSAAPCGHCRQFLQEIRDAPEIKILITDPNNSADSDSAA-----DSDGFLRLGSFLPHR 152
Query: 209 FGPHDLLDQETPLMLEQHDNRLDLLHQDDSDTDTSSANLCNGNDNS 346
FGP DLL ++ PL+LE HDN L + SD D ++CNGN +S
Sbjct: 153 FGPDDLLGKDHPLLLESHDNHLKI-----SDLD----SICNGNTDS 189
>gb|AAF03357.1|AF134486_1 cytidine deaminase 1, partial [Arabidopsis thaliana]
Length = 237
Score = 92.0 bits (227), Expect = 7e-17
Identities = 50/106 (47%), Positives = 65/106 (61%)
Frame = +2
Query: 29 AVSAAPCGHCRQFYQELRHSASLQILITDEDNCVQNHDRIGMLENKAPDFMPLLKFLPHP 208
AVSAAPCGHCRQF QE+R + ++ILITD +N + + F+ L FLPH
Sbjct: 34 AVSAAPCGHCRQFLQEIRDAPEIKILITDPNNSADSDSAA-----DSDGFLRLGSFLPHR 88
Query: 209 FGPHDLLDQETPLMLEQHDNRLDLLHQDDSDTDTSSANLCNGNDNS 346
FGP DLL ++ PL+LE HDN L + SD D ++CNGN +S
Sbjct: 89 FGPDDLLGKDHPLLLESHDNHLKI-----SDLD----SICNGNTDS 125
>ref|XP_002514140.1| cytidine deaminase 1, 2, 7, putative [Ricinus communis]
gi|223546596|gb|EEF48094.1| cytidine deaminase 1, 2, 7,
putative [Ricinus communis]
Length = 311
Score = 92.0 bits (227), Expect = 7e-17
Identities = 47/103 (45%), Positives = 63/103 (61%)
Frame = +2
Query: 14 SLLAVAVSAAPCGHCRQFYQELRHSASLQILITDEDNCVQNHDRIGMLENKAPDFMPLLK 193
+L VAVSAAPCGHCRQF+QE+R + +QILIT + N N+D+ F L
Sbjct: 93 NLKYVAVSAAPCGHCRQFFQEIRDAPDIQILITGDSNNTNNNDQ---SNGDIKRFDTLSN 149
Query: 194 FLPHPFGPHDLLDQETPLMLEQHDNRLDLLHQDDSDTDTSSAN 322
LP FGP+DLLD+ PL+LE+H+N + L + D S+ N
Sbjct: 150 LLPQRFGPYDLLDKSVPLVLEKHNNHMSLQNDDISNNSKKVPN 192
>gb|AAM62679.1| putative cytidine deaminase [Arabidopsis thaliana]
Length = 301
Score = 92.0 bits (227), Expect = 7e-17
Identities = 50/106 (47%), Positives = 65/106 (61%)
Frame = +2
Query: 29 AVSAAPCGHCRQFYQELRHSASLQILITDEDNCVQNHDRIGMLENKAPDFMPLLKFLPHP 208
AVSAAPCGHCRQF QE+R + ++ILITD +N + + F+ L FLPH
Sbjct: 98 AVSAAPCGHCRQFLQEIRDAPEIKILITDPNNSADSDSAA-----DSDGFLRLGSFLPHR 152
Query: 209 FGPHDLLDQETPLMLEQHDNRLDLLHQDDSDTDTSSANLCNGNDNS 346
FGP DLL ++ PL+LE HDN L + SD D ++CNGN +S
Sbjct: 153 FGPDDLLGKDHPLLLESHDNHLKI-----SDLD----SICNGNTDS 189
>ref|XP_007012863.1| Cytidine deaminase [Theobroma cacao] gi|508783226|gb|EOY30482.1|
Cytidine deaminase [Theobroma cacao]
Length = 304
Score = 91.7 bits (226), Expect = 1e-16
Identities = 50/111 (45%), Positives = 65/111 (58%)
Frame = +2
Query: 11 PSLLAVAVSAAPCGHCRQFYQELRHSASLQILITDEDNCVQNHDRIGMLENKAPDFMPLL 190
P L +AVSAAPCGHCRQF QELR + +++LIT D+ +N +K +F PL
Sbjct: 92 PLLKYLAVSAAPCGHCRQFLQELRGAPDVKLLITSSDDEKENKTN-NNYNDKDQEFTPLS 150
Query: 191 KFLPHPFGPHDLLDQETPLMLEQHDNRLDLLHQDDSDTDTSSANLCNGNDN 343
FLPH FGP DLL+++ PL+LE H N L ++LCNG N
Sbjct: 151 HFLPHRFGPDDLLEKDVPLLLEPHRNGLSFY-----------SDLCNGKIN 190
>ref|XP_002308296.1| cytidine deaminase 1 family protein [Populus trichocarpa]
gi|222854272|gb|EEE91819.1| cytidine deaminase 1 family
protein [Populus trichocarpa]
Length = 315
Score = 89.7 bits (221), Expect = 4e-16
Identities = 48/91 (52%), Positives = 57/91 (62%)
Frame = +2
Query: 11 PSLLAVAVSAAPCGHCRQFYQELRHSASLQILITDEDNCVQNHDRIGMLENKAPDFMPLL 190
PSL +AVSAAPCGHCRQF QE+RH+ +QILIT + N L NK F PL
Sbjct: 92 PSLKYIAVSAAPCGHCRQFLQEIRHAPDVQILITGDS--TNNQSYKNDLANK-QQFEPLS 148
Query: 191 KFLPHPFGPHDLLDQETPLMLEQHDNRLDLL 283
LPH FGP DLLD++ PL+LE N L +
Sbjct: 149 CLLPHRFGPDDLLDKDIPLLLETRHNNLSFV 179
>ref|XP_006298210.1| hypothetical protein CARUB_v10014260mg [Capsella rubella]
gi|482566919|gb|EOA31108.1| hypothetical protein
CARUB_v10014260mg [Capsella rubella]
Length = 303
Score = 89.4 bits (220), Expect = 5e-16
Identities = 49/106 (46%), Positives = 65/106 (61%)
Frame = +2
Query: 17 LLAVAVSAAPCGHCRQFYQELRHSASLQILITDEDNCVQNHDRIGMLENKAPDFMPLLKF 196
L +VSAAPCGHCRQF QE+R ++ ++ILITD N + + F+ L F
Sbjct: 94 LKCFSVSAAPCGHCRQFLQEIRGASEIKILITDPKNSADSDSAA-----DSDGFLRLGSF 148
Query: 197 LPHPFGPHDLLDQETPLMLEQHDNRLDLLHQDDSDTDTSSANLCNG 334
LPH FGP DLL+++ PL+LE HDNRL + SD D ++CNG
Sbjct: 149 LPHRFGPDDLLEKDIPLLLEPHDNRLAV-----SDLD----SICNG 185
>gb|AFK48519.1| unknown [Lotus japonicus]
Length = 294
Score = 88.2 bits (217), Expect = 1e-15
Identities = 47/93 (50%), Positives = 55/93 (59%)
Frame = +2
Query: 14 SLLAVAVSAAPCGHCRQFYQELRHSASLQILITDEDNCVQNHDRIGMLENKAPDFMPLLK 193
+L + AVSAAPCGHCRQF QELR + +QILIT E + P F PL
Sbjct: 89 NLHSFAVSAAPCGHCRQFLQELRGAPEIQILITSEPD---------------PKFTPLSH 133
Query: 194 FLPHPFGPHDLLDQETPLMLEQHDNRLDLLHQD 292
FLPH F PHDLL PL+LE H N L LL ++
Sbjct: 134 FLPHRFSPHDLLPPRAPLLLEYHHNGLTLLREN 166
>ref|XP_002883984.1| hypothetical protein ARALYDRAFT_480515 [Arabidopsis lyrata subsp.
lyrata] gi|297329824|gb|EFH60243.1| hypothetical protein
ARALYDRAFT_480515 [Arabidopsis lyrata subsp. lyrata]
Length = 301
Score = 88.2 bits (217), Expect = 1e-15
Identities = 49/117 (41%), Positives = 63/117 (53%), Gaps = 7/117 (5%)
Frame = +2
Query: 29 AVSAAPCGHCRQFYQELRHSASLQILITDEDNCVQNHDRIGMLENKAPDFMPLLKFLPHP 208
AVSAAPCGHCRQF QE+R + ++ILITD N + + F+ L FLPH
Sbjct: 98 AVSAAPCGHCRQFLQEIRDAPEIKILITDPKNSADSDSAA-----DSDGFLRLGSFLPHR 152
Query: 209 FGPHDLLDQETPLMLEQHDNRLDLLHQD-------DSDTDTSSANLCNGNDNSGKFS 358
FGP DLL+++ PL+LE HDN L + D DS D L N + +S
Sbjct: 153 FGPDDLLEKDLPLLLEPHDNHLKISDLDSIRNGITDSSADLKQTALAAANRSYAPYS 209
>ref|XP_004287542.1| PREDICTED: cytidine deaminase-like [Fragaria vesca subsp. vesca]
Length = 291
Score = 87.8 bits (216), Expect = 1e-15
Identities = 43/99 (43%), Positives = 62/99 (62%)
Frame = +2
Query: 11 PSLLAVAVSAAPCGHCRQFYQELRHSASLQILITDEDNCVQNHDRIGMLENKAPDFMPLL 190
P L VAVSAAPCGHCRQF+QE+R + + ILIT +++ +D+ F PL
Sbjct: 92 PRLDYVAVSAAPCGHCRQFFQEIRRAQDINILITSDESGDDENDK------SCGQFSPLR 145
Query: 191 KFLPHPFGPHDLLDQETPLMLEQHDNRLDLLHQDDSDTD 307
LP FGP DLL ++ PL+LE+H+N L +++ ++ D
Sbjct: 146 HLLPRRFGPEDLLGEDVPLVLEKHNNALSFINKPETFGD 184