BLASTX 2.2.25 [Feb-01-2011]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= Mentha23_contig00035461
         (311 letters)

Database: ./nr 
           38,876,450 sequences; 13,856,398,315 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gb|EYU17726.1| hypothetical protein MIMGU_mgv1a003168mg [Mimulus...    89   5e-16
ref|XP_004236251.1| PREDICTED: uncharacterized protein LOC101264...    84   2e-14
ref|XP_007211281.1| hypothetical protein PRUPE_ppa003019mg [Prun...    65   1e-08
ref|XP_002272555.1| PREDICTED: uncharacterized protein LOC100264...    65   1e-08
emb|CAN62303.1| hypothetical protein VITISV_023688 [Vitis vinifera]    65   1e-08
ref|XP_006290754.1| hypothetical protein CARUB_v10016853mg [Caps...    65   1e-08
ref|XP_006483935.1| PREDICTED: ARM REPEAT PROTEIN INTERACTING WI...    63   5e-08
ref|XP_006438283.1| hypothetical protein CICLE_v10030994mg [Citr...    63   5e-08
ref|XP_002875325.1| armadillo/beta-catenin repeat family protein...    63   5e-08
ref|NP_189292.1| protein ARMADILLO REPEAT ONLY 4 [Arabidopsis th...    62   6e-08
ref|XP_002314601.2| armadillo/beta-catenin repeat family protein...    62   8e-08
gb|EYU22527.1| hypothetical protein MIMGU_mgv1a003037mg [Mimulus...    62   1e-07
gb|EPS71836.1| hypothetical protein M569_02913 [Genlisea aurea]        61   1e-07
ref|XP_007158408.1| hypothetical protein PHAVU_002G150500g [Phas...    61   2e-07
ref|XP_006395542.1| hypothetical protein EUTSA_v10003833mg [Eutr...    61   2e-07
emb|CBI14968.3| unnamed protein product [Vitis vinifera]               61   2e-07
emb|CAN76390.1| hypothetical protein VITISV_023591 [Vitis vinifera]    61   2e-07
ref|XP_003525564.1| PREDICTED: ARM REPEAT PROTEIN INTERACTING WI...    60   3e-07
ref|XP_007044776.1| Armadillo repeat only 4 [Theobroma cacao] gi...    60   4e-07
ref|XP_004142965.1| PREDICTED: uncharacterized protein LOC101207...    60   4e-07

>gb|EYU17726.1| hypothetical protein MIMGU_mgv1a003168mg [Mimulus guttatus]
          Length = 603

 Score = 89.4 bits (220), Expect = 5e-16
 Identities = 52/115 (45%), Positives = 74/115 (64%), Gaps = 12/115 (10%)
 Frame = -2

Query: 310 MDVNLEEFAEANSQKNP-NNLLSIVQINKEISRKGNIKFSE-----------KERDRETE 167
           +DV+L+EF E+ + K P N++ S+V+INKE+++K    +             KE++RE+E
Sbjct: 286 VDVDLDEFKESANPKKPVNSIHSLVEINKEMTKKSIHSYDSSNSLEGSGKRRKEKERESE 345

Query: 166 APEVKSRLKISCASALSILAKSNLFNSGKITDTKALLVLAXXXXXXXXXXXINCL 2
           +PEVKS LK+SCA+AL  LA+ +L NS KIT+TKALLVLA            NCL
Sbjct: 346 SPEVKSSLKLSCANALRKLARGSLSNSKKITETKALLVLAKTIETESGDLKTNCL 400


>ref|XP_004236251.1| PREDICTED: uncharacterized protein LOC101264310 isoform 1 [Solanum
           lycopersicum] gi|460381023|ref|XP_004236252.1|
           PREDICTED: uncharacterized protein LOC101264310 isoform
           2 [Solanum lycopersicum]
          Length = 600

 Score = 84.0 bits (206), Expect = 2e-14
 Identities = 55/117 (47%), Positives = 71/117 (60%), Gaps = 14/117 (11%)
 Frame = -2

Query: 310 MDVNLEEFAEANSQKNPNNLLSIVQINKEISR--------------KGNIKFSEKERDRE 173
           MDV L+E  +A  +K P+ L S+VQINKE++R              +G    ++KE+DRE
Sbjct: 289 MDVVLDEPKDAPPRKTPS-LHSLVQINKEMARNNYSVHSNSMDGSSRGGHYGNKKEKDRE 347

Query: 172 TEAPEVKSRLKISCASALSILAKSNLFNSGKITDTKALLVLAXXXXXXXXXXXINCL 2
            E PEVK++LK+SCA AL  LAK +L NS KIT+TKALL LA           INCL
Sbjct: 348 LEPPEVKAKLKVSCAMALWKLAKGSLMNSRKITETKALLCLAKIIEKEKGELQINCL 404


>ref|XP_007211281.1| hypothetical protein PRUPE_ppa003019mg [Prunus persica]
           gi|462407016|gb|EMJ12480.1| hypothetical protein
           PRUPE_ppa003019mg [Prunus persica]
          Length = 611

 Score = 65.1 bits (157), Expect = 1e-08
 Identities = 42/110 (38%), Positives = 55/110 (50%), Gaps = 20/110 (18%)
 Frame = -2

Query: 271 QKNPNNLLSIVQINKEISRKGNIKFSE--------------------KERDRETEAPEVK 152
           Q    ++ ++VQINKE++ KG+   S                     KERDRE E+PEVK
Sbjct: 298 QTGKPSIHNLVQINKELAVKGSNANSRSSSFSSHYHSDGSSRGAHYRKERDREAESPEVK 357

Query: 151 SRLKISCASALSILAKSNLFNSGKITDTKALLVLAXXXXXXXXXXXINCL 2
             LK+ CA AL  L K  L NS K+T+TK L+ LA           +NCL
Sbjct: 358 LELKVGCAEALWKLCKECLLNSRKVTETKGLICLAKIIETEVGELQLNCL 407


>ref|XP_002272555.1| PREDICTED: uncharacterized protein LOC100264922 [Vitis vinifera]
          Length = 605

 Score = 65.1 bits (157), Expect = 1e-08
 Identities = 43/120 (35%), Positives = 59/120 (49%), Gaps = 19/120 (15%)
 Frame = -2

Query: 304 VNLEEFAEANSQKNPN-NLLSIVQINKEISR------------------KGNIKFSEKER 182
           V L  F    ++ +P  ++ S+VQINKE+                    +G+ +     +
Sbjct: 286 VTLLSFEIVMNENDPKMSIHSLVQINKEVGESSTVNAKLHLNSCSSMYGEGSGRGGRHNK 345

Query: 181 DRETEAPEVKSRLKISCASALSILAKSNLFNSGKITDTKALLVLAXXXXXXXXXXXINCL 2
           DRE E PEVK  LK SCA AL +LA+ N+ NS +IT+TK LL LA            NCL
Sbjct: 346 DRENEKPEVKINLKTSCAEALRMLARGNVSNSKRITETKGLLCLAKLIEKEKGDLQFNCL 405


>emb|CAN62303.1| hypothetical protein VITISV_023688 [Vitis vinifera]
          Length = 943

 Score = 65.1 bits (157), Expect = 1e-08
 Identities = 43/120 (35%), Positives = 59/120 (49%), Gaps = 19/120 (15%)
 Frame = -2

Query: 304 VNLEEFAEANSQKNPN-NLLSIVQINKEISR------------------KGNIKFSEKER 182
           V L  F    ++ +P  ++ S+VQINKE+                    +G+ +     +
Sbjct: 624 VTLLSFEIVMNENDPKMSIHSLVQINKEVGESSTVNAKLHLNSSSSMYGEGSGRGGRHNK 683

Query: 181 DRETEAPEVKSRLKISCASALSILAKSNLFNSGKITDTKALLVLAXXXXXXXXXXXINCL 2
           DRE E PEVK  LK SCA AL +LA+ N+ NS +IT+TK LL LA            NCL
Sbjct: 684 DRENEKPEVKINLKTSCAEALRMLARGNVSNSKRITETKGLLCLAKLIEKEKGDLQFNCL 743


>ref|XP_006290754.1| hypothetical protein CARUB_v10016853mg [Capsella rubella]
           gi|482559461|gb|EOA23652.1| hypothetical protein
           CARUB_v10016853mg [Capsella rubella]
          Length = 614

 Score = 64.7 bits (156), Expect = 1e-08
 Identities = 42/123 (34%), Positives = 62/123 (50%), Gaps = 22/123 (17%)
 Frame = -2

Query: 304 VNLEEFAEANSQKNPNNLLSIVQINKEI-------------SRKGNI---------KFSE 191
           ++L+ F +       N++ S+VQ+NK+I             S K N+         K   
Sbjct: 290 LSLDVFVDDLQLSKHNSIHSLVQMNKDIEKDPSLKIPRPFKSSKSNVYREIGGSGSKTGN 349

Query: 190 KERDRETEAPEVKSRLKISCASALSILAKSNLFNSGKITDTKALLVLAXXXXXXXXXXXI 11
            +++R+ E PEVK  LK+SCA AL +LA+ N+ NS +IT+TK LL LA            
Sbjct: 350 FKKERDNENPEVKHELKVSCAEALWMLARGNVANSKRITETKGLLTLAKIVEKEVGELQY 409

Query: 10  NCL 2
           NCL
Sbjct: 410 NCL 412


>ref|XP_006483935.1| PREDICTED: ARM REPEAT PROTEIN INTERACTING WITH ABF2-like [Citrus
           sinensis]
          Length = 608

 Score = 62.8 bits (151), Expect = 5e-08
 Identities = 40/109 (36%), Positives = 58/109 (53%), Gaps = 16/109 (14%)
 Frame = -2

Query: 280 ANSQKNPNNLLSIVQINKEISRKGNI----------------KFSEKERDRETEAPEVKS 149
           ANS K   ++ +IVQINKE+ +   +                +  +  +DRE E PEVK 
Sbjct: 302 ANSGKQ--SIHTIVQINKEMEKNSFVGSKNYRPYLYSEYCSSRSGQNRKDRENEKPEVKI 359

Query: 148 RLKISCASALSILAKSNLFNSGKITDTKALLVLAXXXXXXXXXXXINCL 2
           +LKI+CA AL +LA+ ++ NS +I++TK LL LA            NCL
Sbjct: 360 KLKIACAEALWMLARGSVANSRRISETKGLLCLAKLVEKEQGELQFNCL 408


>ref|XP_006438283.1| hypothetical protein CICLE_v10030994mg [Citrus clementina]
           gi|557540479|gb|ESR51523.1| hypothetical protein
           CICLE_v10030994mg [Citrus clementina]
          Length = 608

 Score = 62.8 bits (151), Expect = 5e-08
 Identities = 40/109 (36%), Positives = 58/109 (53%), Gaps = 16/109 (14%)
 Frame = -2

Query: 280 ANSQKNPNNLLSIVQINKEISRKGNI----------------KFSEKERDRETEAPEVKS 149
           ANS K   ++ +IVQINKE+ +   +                +  +  +DRE E PEVK 
Sbjct: 302 ANSGKQ--SIHTIVQINKEMEKNSFVGSKNYRPYLYSEYCSSRSGQNRKDRENEKPEVKI 359

Query: 148 RLKISCASALSILAKSNLFNSGKITDTKALLVLAXXXXXXXXXXXINCL 2
           +LKI+CA AL +LA+ ++ NS +I++TK LL LA            NCL
Sbjct: 360 KLKIACAEALWMLARGSVANSRRISETKGLLCLAKLVEKEQGELQFNCL 408


>ref|XP_002875325.1| armadillo/beta-catenin repeat family protein [Arabidopsis lyrata
           subsp. lyrata] gi|297321163|gb|EFH51584.1|
           armadillo/beta-catenin repeat family protein
           [Arabidopsis lyrata subsp. lyrata]
          Length = 614

 Score = 62.8 bits (151), Expect = 5e-08
 Identities = 41/123 (33%), Positives = 63/123 (51%), Gaps = 22/123 (17%)
 Frame = -2

Query: 304 VNLEEFAEANSQKNPNNLLSIVQINKEISRKGNIKF-----SEK---------------- 188
           ++L+ F +       N++ S+VQ+NKE+ +  + KF     S K                
Sbjct: 290 LSLDVFFDDIHLSKHNSIHSLVQMNKEVEKDPSSKFYRPLKSSKSNVYREIGGSGSRTGN 349

Query: 187 -ERDRETEAPEVKSRLKISCASALSILAKSNLFNSGKITDTKALLVLAXXXXXXXXXXXI 11
            +++R+ E PEVK  LK++CA AL +LA+ N+ NS +IT+TK LL LA            
Sbjct: 350 FKKERDNENPEVKHELKVNCAEALWMLARGNVANSRRITETKGLLSLAKIVEKEVGELQY 409

Query: 10  NCL 2
           NCL
Sbjct: 410 NCL 412


>ref|NP_189292.1| protein ARMADILLO REPEAT ONLY 4 [Arabidopsis thaliana]
           gi|1402879|emb|CAA66810.1| hypothetical protein
           [Arabidopsis thaliana] gi|1495247|emb|CAA66220.1| orf 05
           [Arabidopsis thaliana] gi|9293939|dbj|BAB01842.1|
           unnamed protein product [Arabidopsis thaliana]
           gi|209414538|gb|ACI46509.1| At3g26600 [Arabidopsis
           thaliana] gi|332643663|gb|AEE77184.1| armadillo repeat
           only 4 protein [Arabidopsis thaliana]
          Length = 615

 Score = 62.4 bits (150), Expect = 6e-08
 Identities = 45/128 (35%), Positives = 61/128 (47%), Gaps = 27/128 (21%)
 Frame = -2

Query: 304 VNLEEFAEANSQKNPNNLLSIVQINKEI---------------------------SRKGN 206
           ++L+ F +       N++ S+VQ+NKE+                           SR GN
Sbjct: 291 LSLDVFVDDIHLSKHNSIHSLVQMNKEVEKDPSSKLYRPLKSSKSNVYRDIGGSGSRTGN 350

Query: 205 IKFSEKERDRETEAPEVKSRLKISCASALSILAKSNLFNSGKITDTKALLVLAXXXXXXX 26
            K   KERD E   PEVK  LK++CA AL +LA+ N+ NS +IT+TK LL LA       
Sbjct: 351 FK---KERDNEN--PEVKHELKVNCAEALWMLARGNVANSRRITETKGLLSLAKIVEKEV 405

Query: 25  XXXXINCL 2
                NCL
Sbjct: 406 GELQYNCL 413


>ref|XP_002314601.2| armadillo/beta-catenin repeat family protein [Populus trichocarpa]
           gi|550329142|gb|EEF00772.2| armadillo/beta-catenin
           repeat family protein [Populus trichocarpa]
          Length = 610

 Score = 62.0 bits (149), Expect = 8e-08
 Identities = 32/65 (49%), Positives = 41/65 (63%)
 Frame = -2

Query: 196 SEKERDRETEAPEVKSRLKISCASALSILAKSNLFNSGKITDTKALLVLAXXXXXXXXXX 17
           S   R+RE E+PEVK +LKISCA AL +LA+ ++ NS +IT+TK LL LA          
Sbjct: 346 SNHRRERENESPEVKHKLKISCAEALWMLARDSVLNSKRITETKGLLCLAKLVEKGEGEL 405

Query: 16  XINCL 2
             NCL
Sbjct: 406 QFNCL 410


>gb|EYU22527.1| hypothetical protein MIMGU_mgv1a003037mg [Mimulus guttatus]
          Length = 613

 Score = 61.6 bits (148), Expect = 1e-07
 Identities = 41/112 (36%), Positives = 55/112 (49%), Gaps = 18/112 (16%)
 Frame = -2

Query: 283 EANSQKNPNNLLSIVQINKEISRK------------------GNIKFSEKERDRETEAPE 158
           E   +    ++ S+VQIN E+ +K                  G+ K     ++RE E PE
Sbjct: 302 EPKVKPEKQSIHSLVQINMELEKKSLFKSGSGSSNLSIHYAEGSCKGLSHRKEREHEKPE 361

Query: 157 VKSRLKISCASALSILAKSNLFNSGKITDTKALLVLAXXXXXXXXXXXINCL 2
           +K  LKISCA AL +LAK ++ NS +ITDTK LL LA            NCL
Sbjct: 362 LKLELKISCAKALWMLAKWSVPNSKRITDTKGLLCLAKLVEAEEGELQRNCL 413


>gb|EPS71836.1| hypothetical protein M569_02913 [Genlisea aurea]
          Length = 636

 Score = 61.2 bits (147), Expect = 1e-07
 Identities = 37/101 (36%), Positives = 53/101 (52%), Gaps = 19/101 (18%)
 Frame = -2

Query: 247 SIVQINKEISRKG----------NIKFSE---------KERDRETEAPEVKSRLKISCAS 125
           SIVQINKE+ +K           ++ +SE           ++RE E PEV+  LK++CA 
Sbjct: 336 SIVQINKEMEKKNLYKPGLGTSLSLHYSEGSSKGGGSSNRKERENEKPEVRHELKVNCAE 395

Query: 124 ALSILAKSNLFNSGKITDTKALLVLAXXXXXXXXXXXINCL 2
           AL +LA+ ++ NS +ITDTK  + LA            NCL
Sbjct: 396 ALWMLARGSVVNSKRITDTKGFICLAKLVETEQGELQSNCL 436


>ref|XP_007158408.1| hypothetical protein PHAVU_002G150500g [Phaseolus vulgaris]
           gi|561031823|gb|ESW30402.1| hypothetical protein
           PHAVU_002G150500g [Phaseolus vulgaris]
          Length = 611

 Score = 60.8 bits (146), Expect = 2e-07
 Identities = 37/102 (36%), Positives = 52/102 (50%), Gaps = 20/102 (19%)
 Frame = -2

Query: 247 SIVQINKEISR--------------------KGNIKFSEKERDRETEAPEVKSRLKISCA 128
           SIVQINKE+ +                    +G+ +     ++RE E P VK +LK+SCA
Sbjct: 311 SIVQINKELGKGSSRGGRHFSNSYSNSYLFMEGSSRGGNHRKERENEDPAVKLQLKVSCA 370

Query: 127 SALSILAKSNLFNSGKITDTKALLVLAXXXXXXXXXXXINCL 2
            AL +LA+ ++ NS KIT+TK +L LA            NCL
Sbjct: 371 EALWMLARGSVINSRKITETKGMLCLAKIVQNEQGELQYNCL 412


>ref|XP_006395542.1| hypothetical protein EUTSA_v10003833mg [Eutrema salsugineum]
           gi|557092181|gb|ESQ32828.1| hypothetical protein
           EUTSA_v10003833mg [Eutrema salsugineum]
          Length = 617

 Score = 60.8 bits (146), Expect = 2e-07
 Identities = 38/109 (34%), Positives = 57/109 (52%), Gaps = 23/109 (21%)
 Frame = -2

Query: 259 NNLLSIVQINKEISRKGNIKF-----SEK------------------ERDRETEAPEVKS 149
           N++ S+VQ+NK+I +  ++K      S K                  +++R+ E PEVK 
Sbjct: 307 NSIHSLVQMNKDIEKDASLKIYRPYKSSKSNVYRDIGVSGSRTTGNFKKERDNENPEVKH 366

Query: 148 RLKISCASALSILAKSNLFNSGKITDTKALLVLAXXXXXXXXXXXINCL 2
            LK++CA AL +LA+ N+ NS +IT+TK LL LA            NCL
Sbjct: 367 ELKVNCAEALWMLARGNVANSRRITETKGLLSLAKIVEKEVGELQYNCL 415


>emb|CBI14968.3| unnamed protein product [Vitis vinifera]
          Length = 1372

 Score = 60.8 bits (146), Expect = 2e-07
 Identities = 31/73 (42%), Positives = 43/73 (58%)
 Frame = -2

Query: 220  SRKGNIKFSEKERDRETEAPEVKSRLKISCASALSILAKSNLFNSGKITDTKALLVLAXX 41
            S +G+ +     +DRE E PE+K +LK+SCA AL  L+K ++ NS KIT+TK L+ LA  
Sbjct: 1088 SSEGSSRGGHNRKDREVETPELKLKLKVSCAEALWKLSKDSVLNSRKITETKGLICLAKI 1147

Query: 40   XXXXXXXXXINCL 2
                      NCL
Sbjct: 1148 IEKEKGELQYNCL 1160


>emb|CAN76390.1| hypothetical protein VITISV_023591 [Vitis vinifera]
          Length = 617

 Score = 60.8 bits (146), Expect = 2e-07
 Identities = 31/73 (42%), Positives = 43/73 (58%)
 Frame = -2

Query: 220 SRKGNIKFSEKERDRETEAPEVKSRLKISCASALSILAKSNLFNSGKITDTKALLVLAXX 41
           S +G+ +     +DRE E PE+K +LK+SCA AL  L+K ++ NS KIT+TK L+ LA  
Sbjct: 348 SSEGSSRGGHNRKDREVETPELKLKLKVSCAEALWKLSKDSVLNSRKITETKGLICLAKI 407

Query: 40  XXXXXXXXXINCL 2
                     NCL
Sbjct: 408 IEKEKGELQYNCL 420


>ref|XP_003525564.1| PREDICTED: ARM REPEAT PROTEIN INTERACTING WITH ABF2-like [Glycine
           max]
          Length = 602

 Score = 60.1 bits (144), Expect = 3e-07
 Identities = 35/85 (41%), Positives = 51/85 (60%)
 Frame = -2

Query: 256 NLLSIVQINKEISRKGNIKFSEKERDRETEAPEVKSRLKISCASALSILAKSNLFNSGKI 77
           NL ++ + N + S +G+   S + RDRE E+PE+++ +KISCA AL  L+K  L +  KI
Sbjct: 321 NLSNVGEANSDGSSRGS---SHQRRDREVESPELRNEVKISCAKALWKLSKGCLSSCRKI 377

Query: 76  TDTKALLVLAXXXXXXXXXXXINCL 2
           T+TK LL LA           +NCL
Sbjct: 378 TETKGLLCLAKIIESESGELQLNCL 402


>ref|XP_007044776.1| Armadillo repeat only 4 [Theobroma cacao]
           gi|508708711|gb|EOY00608.1| Armadillo repeat only 4
           [Theobroma cacao]
          Length = 616

 Score = 59.7 bits (143), Expect = 4e-07
 Identities = 42/127 (33%), Positives = 62/127 (48%), Gaps = 26/127 (20%)
 Frame = -2

Query: 304 VNLEEFAE-ANSQKNPNNLLSIVQINKEISRKGNIKFSEKE------------------- 185
           ++ E F E + +Q    ++ SIVQINKE+ +  +I  + +                    
Sbjct: 291 LSFETFVEDSRTQMGKQSIHSIVQINKEMEKNSSIGSNSRNYSYRPYTNSYSNLHMEGSS 350

Query: 184 ------RDRETEAPEVKSRLKISCASALSILAKSNLFNSGKITDTKALLVLAXXXXXXXX 23
                 ++RE E PEVK +LKI+ A AL +LAK ++ NS +IT+TK LL LA        
Sbjct: 351 RGGNHRKERENEKPEVKIQLKINGAEALWMLAKGSVSNSRRITETKGLLCLAKLVEKEQG 410

Query: 22  XXXINCL 2
               NCL
Sbjct: 411 ELQYNCL 417


>ref|XP_004142965.1| PREDICTED: uncharacterized protein LOC101207247 [Cucumis sativus]
           gi|449500301|ref|XP_004161060.1| PREDICTED:
           uncharacterized LOC101207247 [Cucumis sativus]
          Length = 606

 Score = 59.7 bits (143), Expect = 4e-07
 Identities = 36/101 (35%), Positives = 55/101 (54%), Gaps = 1/101 (0%)
 Frame = -2

Query: 301 NLEEFA-EANSQKNPNNLLSIVQINKEISRKGNIKFSEKERDRETEAPEVKSRLKISCAS 125
           NLE+   +   ++NPN      + N   + +G I+     ++R  E PEVK +LKI+CA 
Sbjct: 309 NLEKKTLDKTMEQNPN-----AKTNALSNMEGGIRAGNSRKERGNERPEVKHKLKITCAE 363

Query: 124 ALSILAKSNLFNSGKITDTKALLVLAXXXXXXXXXXXINCL 2
           AL +LAK ++ NS +I +TK LL +A           +NCL
Sbjct: 364 ALWLLAKGSVSNSRRICETKGLLCMAKMVEKEEGELQMNCL 404