BLASTX nr result
ID: Magnolia22_contig00005146
seq
BLASTX 2.2.26 [Sep-21-2011]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Magnolia22_contig00005146
(1628 letters)
Database: ./nr
115,041,592 sequences; 42,171,959,267 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
XP_010253990.1 PREDICTED: probable (S)-N-methylcoclaurine 3'-hyd... 801 0.0
XP_010253989.1 PREDICTED: probable (S)-N-methylcoclaurine 3'-hyd... 707 0.0
Q9FXW4.1 RecName: Full=Probable (S)-N-methylcoclaurine 3'-hydrox... 532 0.0
ABS19627.1 (S)-N-methylcoclaurine-3'-hydroxylase [Coptis chinensis] 527 0.0
BAF80448.1 corytuberine synthase [Coptis japonica var. dissecta] 517 e-177
AKH61487.1 NMCH CYP80B1 P450 N-methylcoclaurine hydroxylase from... 509 e-174
AJD20229.1 corytuberine synthase [Sinopodophyllum hexandrum] 509 e-174
O64899.1 RecName: Full=(S)-N-methylcoclaurine 3'-hydroxylase iso... 509 e-174
ACO90224.1 putative (S)-N-methylcoclaurine 3'-hydroxylase, parti... 508 e-173
O64900.1 RecName: Full=(S)-N-methylcoclaurine 3'-hydroxylase iso... 507 e-173
AAU20767.1 (S)-N-methylcoclaurine 3'-hydroxylase [Thalictrum fla... 505 e-172
Q9SP06.1 RecName: Full=(S)-N-methylcoclaurine 3'-hydroxylase iso... 503 e-172
AAF61400.1 (S)-N-methylcoclaurine 3'-hydroxylase, partial [Papav... 501 e-171
XP_002283461.2 PREDICTED: probable (S)-N-methylcoclaurine 3'-hyd... 493 e-167
XP_019072647.1 PREDICTED: probable (S)-N-methylcoclaurine 3'-hyd... 488 e-165
XP_002283415.2 PREDICTED: probable (S)-N-methylcoclaurine 3'-hyd... 487 e-164
XP_019223612.1 PREDICTED: probable (S)-N-methylcoclaurine 3'-hyd... 485 e-164
XP_009610421.1 PREDICTED: (S)-N-methylcoclaurine 3'-hydroxylase ... 483 e-164
XP_006353352.1 PREDICTED: probable (S)-N-methylcoclaurine 3'-hyd... 483 e-164
XP_004234364.1 PREDICTED: probable (S)-N-methylcoclaurine 3'-hyd... 479 e-162
>XP_010253990.1 PREDICTED: probable (S)-N-methylcoclaurine 3'-hydroxylase isozyme 2
[Nelumbo nucifera]
Length = 485
Score = 801 bits (2068), Expect = 0.0
Identities = 387/463 (83%), Positives = 427/463 (92%)
Frame = +2
Query: 65 KPSTKNLPPGPFAWPIIGTLLPKLKKQPHIELSKLAKTYGPLMLLKFGVEPVVVASSHTA 244
KPS NLPPGPF+WPIIGTLLPKLKKQPH+ELSKLA+ +GPLMLLKFGVEPVVVASSH A
Sbjct: 22 KPSPNNLPPGPFSWPIIGTLLPKLKKQPHVELSKLAQRFGPLMLLKFGVEPVVVASSHVA 81
Query: 245 AMEVLKDQDRVLSGRFAPHSTRIKGYIEHSMVWADCTDYWKMIRKICRTELFSTKMLDAQ 424
A+EVLK+QDR+LSGRFAPHS RIKGYIEHSMVWADCTDYWKM+RK+ RTELFSTKMLD Q
Sbjct: 82 AVEVLKNQDRLLSGRFAPHSVRIKGYIEHSMVWADCTDYWKMVRKVWRTELFSTKMLDIQ 141
Query: 425 ASAREAKVVELIEFLRRKDGEIVKFADVIFGAILNVLGALIFNKDVFDFEDKTDNNLGMK 604
A ARE KV EL++FL RK+GE V FADVIFG+ILN+LGALIF+KDV+DFED+TDNNLGMK
Sbjct: 142 AHAREEKVSELMKFLIRKEGEKVNFADVIFGSILNILGALIFSKDVYDFEDRTDNNLGMK 201
Query: 605 GMIRQLMILASIPNLADLYPILGRSDLQGLRKASAVCVKRMNDSWAGIVKERRASNDQSK 784
GMIRQLMILA+IPNLADLYPILG SD QGLRKASA CVKRMN+SWA IVK+RR ++D SK
Sbjct: 202 GMIRQLMILAAIPNLADLYPILGGSDFQGLRKASAACVKRMNESWAAIVKQRRKNDDHSK 261
Query: 785 NDFLQVLIDAGFTDAQIDAMLLETFGPGSDTSTSTIEWAMAELLRNPTKLIKVREELDKV 964
NDFLQVL+D+GF+D QIDAMLLETFGPGSDTSTSTIEWAMAELLRNP KL+KVREELD+V
Sbjct: 262 NDFLQVLLDSGFSDPQIDAMLLETFGPGSDTSTSTIEWAMAELLRNPEKLVKVREELDRV 321
Query: 965 IGPNRAVKESDLPHLPYLHACVKETLRLHPPVTFLLPHRAIETCEVMNYTVPKGCQLMVN 1144
I + VKESDLP+LPYLHACVKETLRLHPPVTFLLPHRA+ETC++MNYT+PKGCQLMVN
Sbjct: 322 IRRSNNVKESDLPNLPYLHACVKETLRLHPPVTFLLPHRAMETCQMMNYTIPKGCQLMVN 381
Query: 1145 TYAIGRDPKTWPNPLSFTPERFLESDVDYQGNDFHYIPFGAGRRICPGLSLATRVVRLIL 1324
TYAIGRD KTW PLSF PERFL S++DYQGNDF YIPFGAGRRICPGLSLATRVVRLIL
Sbjct: 382 TYAIGRDSKTWEKPLSFLPERFLNSELDYQGNDFQYIPFGAGRRICPGLSLATRVVRLIL 441
Query: 1325 GSLIHTFEWSLPNGMNPDELDMTDKFGLALLKDEPLLVIPKAR 1453
SL+HTF+WSLP+GM+PDELDM DKFGLAL KD PL+VIPK R
Sbjct: 442 ASLLHTFDWSLPDGMHPDELDMNDKFGLALQKDIPLVVIPKLR 484
>XP_010253989.1 PREDICTED: probable (S)-N-methylcoclaurine 3'-hydroxylase isozyme 2
[Nelumbo nucifera]
Length = 486
Score = 707 bits (1825), Expect = 0.0
Identities = 339/464 (73%), Positives = 394/464 (84%), Gaps = 1/464 (0%)
Frame = +2
Query: 65 KPSTKNLPPGPFAWPIIGTLLPKLKKQPHIELSKLAKTYGPLMLLKFGVEPVVVASSHTA 244
KPS+K LPPGPF+WPIIGT LP +P++EL KLA+ YGPLML +FG E VVVAS+H A
Sbjct: 22 KPSSKKLPPGPFSWPIIGTQLPSPTMKPNLELFKLAQRYGPLMLFRFGFENVVVASNHVA 81
Query: 245 AMEVLKDQDRVLSGRFAPHSTRIKGYIEHSMVWADCTDYWKMIRKICRTELFSTKMLDAQ 424
AMEVLK+QDRVLSGRF +S R+KGYIE+SMVWADCTDYWKM+RKI RTELFSTKMLD
Sbjct: 82 AMEVLKNQDRVLSGRFKANSVRVKGYIEYSMVWADCTDYWKMVRKILRTELFSTKMLDVH 141
Query: 425 ASAREAKVVELIEFLRRKDGEIVKFADVIFGAILNVLGALIFNKDVFDFEDKTDNNLGMK 604
A RE KV EL++FLRRK+GE V F DVIFG ILN+LGALI++KDV+DFEDKTD NLGMK
Sbjct: 142 AHVREEKVSELMKFLRRKEGEEVNFVDVIFGCILNMLGALIYSKDVYDFEDKTDINLGMK 201
Query: 605 GMIRQLMILASIPNLADLYPIL-GRSDLQGLRKASAVCVKRMNDSWAGIVKERRASNDQS 781
GMIRQLMILA+ PN+ADLYPI SD QGLRK SA CVKRM++SWA I+ ERR +ND +
Sbjct: 202 GMIRQLMILAATPNIADLYPIFFDGSDFQGLRKESAACVKRMSESWAAIINERRKNNDHT 261
Query: 782 KNDFLQVLIDAGFTDAQIDAMLLETFGPGSDTSTSTIEWAMAELLRNPTKLIKVREELDK 961
KND LQVL+D+GF+D QIDA+ LETFGPGSDTS STIEWA+AELLRNP KL+K+ EELD+
Sbjct: 262 KNDLLQVLLDSGFSDPQIDAIFLETFGPGSDTSASTIEWALAELLRNPEKLVKLHEELDR 321
Query: 962 VIGPNRAVKESDLPHLPYLHACVKETLRLHPPVTFLLPHRAIETCEVMNYTVPKGCQLMV 1141
VIG N VK+SDLP+LPYLHACVKETLRLHPPV FL+PH A+E+CEVMNYT+PKG +++V
Sbjct: 322 VIGRNNTVKDSDLPNLPYLHACVKETLRLHPPVPFLIPHIALESCEVMNYTIPKGSEVLV 381
Query: 1142 NTYAIGRDPKTWPNPLSFTPERFLESDVDYQGNDFHYIPFGAGRRICPGLSLATRVVRLI 1321
N YAIGRDP TW NP SF PERFL S+VDYQGN F YIPFGAGRR+CPG+SL TRVVRLI
Sbjct: 382 NLYAIGRDPTTWDNPNSFLPERFLNSEVDYQGNHFQYIPFGAGRRMCPGMSLGTRVVRLI 441
Query: 1322 LGSLIHTFEWSLPNGMNPDELDMTDKFGLALLKDEPLLVIPKAR 1453
L +L+HTF+WSLP GM+ DELDM D+FG+ K+ PL+VIP R
Sbjct: 442 LAALVHTFDWSLPGGMHQDELDMADRFGVGFQKETPLVVIPTLR 485
>Q9FXW4.1 RecName: Full=Probable (S)-N-methylcoclaurine 3'-hydroxylase isozyme
2; AltName: Full=Cytochrome P450 80B2 BAB12433.1
(S)-N-methylcoclaurine-3'-hydroxylase [Coptis japonica]
Length = 488
Score = 532 bits (1370), Expect = 0.0
Identities = 259/466 (55%), Positives = 345/466 (74%), Gaps = 1/466 (0%)
Frame = +2
Query: 62 RKPSTKNLPPGPFAWPIIGTLLPKLKKQPHIELSKLAKTYGPLMLLKFGVEPVVVASSHT 241
R KNLPPGP PI+G LL +L +PH E +KLA+ YG L LK G + VVVASS
Sbjct: 22 RDSRPKNLPPGPRPSPIVGNLL-QLGDKPHAEFAKLAQKYGELFSLKLGSQTVVVASSPA 80
Query: 242 AAMEVLKDQDRVLSGRFAPHSTRIKGYIEHSMVWADCTDYWKMIRKICRTELFSTKMLDA 421
AA E+LK D++LSGR+ S R+K ++E+S+VW++C D WK++RK+CRTELF+ KM+++
Sbjct: 81 AAAEILKTHDKILSGRYVFQSFRVKEHVENSIVWSECNDNWKLLRKVCRTELFTPKMIES 140
Query: 422 QASAREAKVVELIEFLRRKDGEIVKFADVIFGAILNVLGALIFNKDVFDFEDKTDNNLGM 601
Q+ REAK E+++FLR K+GE+VK +V+FG ++N+ G LIF+KDVFD ED T ++ +
Sbjct: 141 QSEIREAKAREMVKFLRGKEGEVVKIVEVVFGTLVNIFGNLIFSKDVFDLEDPTGGSVEL 200
Query: 602 KGMIRQLMILASIPNLADLYPILGRSDLQGLRKASAVCVKRMNDSWAGIVKERRASN-DQ 778
K + +L+ + + N AD +PI+G+ DL G R+A A ++++ D W ++KERR + +
Sbjct: 201 KEHLWKLLDMGNSTNPADYFPIMGKLDLFGQRRAVAEVLQQIYDVWGVMLKERRGTKGSE 260
Query: 779 SKNDFLQVLIDAGFTDAQIDAMLLETFGPGSDTSTSTIEWAMAELLRNPTKLIKVREELD 958
SKNDF+ VL++AG D +I+A+L+E FG G++TS STIEWA+ EL + P + K+R EL
Sbjct: 261 SKNDFVDVLLNAGLDDQKINALLMELFGAGTETSASTIEWAITELTKKPLVVSKIRLELV 320
Query: 959 KVIGPNRAVKESDLPHLPYLHACVKETLRLHPPVTFLLPHRAIETCEVMNYTVPKGCQLM 1138
V+G N VKESDLPHLPYL A VKETLRLHPP LLP RA+ETC VMNYT+PK CQ+M
Sbjct: 321 NVVGDN-TVKESDLPHLPYLQAFVKETLRLHPPTPLLLPRRALETCTVMNYTIPKECQIM 379
Query: 1139 VNTYAIGRDPKTWPNPLSFTPERFLESDVDYQGNDFHYIPFGAGRRICPGLSLATRVVRL 1318
VN +AIGRDPKTW +PL+F PERFL SDVDY+GNDF IPFG GRRICPGL LA++ L
Sbjct: 380 VNAWAIGRDPKTWDDPLNFKPERFLSSDVDYKGNDFELIPFGGGRRICPGLPLASQFSNL 439
Query: 1319 ILGSLIHTFEWSLPNGMNPDELDMTDKFGLALLKDEPLLVIPKARA 1456
I+ +L+ FEWSLP GM+ EL M +KFGL L KD PLL++ KARA
Sbjct: 440 IVATLVQNFEWSLPQGMSTSELSMDEKFGLTLQKDPPLLIVLKARA 485
>ABS19627.1 (S)-N-methylcoclaurine-3'-hydroxylase [Coptis chinensis]
Length = 488
Score = 527 bits (1357), Expect = 0.0
Identities = 257/465 (55%), Positives = 341/465 (73%), Gaps = 1/465 (0%)
Frame = +2
Query: 62 RKPSTKNLPPGPFAWPIIGTLLPKLKKQPHIELSKLAKTYGPLMLLKFGVEPVVVASSHT 241
R P KNLPPGP PI+G LL +L +P E +KLA+ YG L LK G + VVVASS
Sbjct: 22 RDPRQKNLPPGPRPLPIVGNLL-QLGDKPRAEFAKLAQKYGQLFSLKLGSQTVVVASSPA 80
Query: 242 AAMEVLKDQDRVLSGRFAPHSTRIKGYIEHSMVWADCTDYWKMIRKICRTELFSTKMLDA 421
AA EVLK D++LSGR+ S R+K ++E+S+VW++C D WK++RK+CRTELF+ KM+++
Sbjct: 81 AAAEVLKTHDKILSGRYVFQSFRVKEHVENSIVWSECNDNWKLLRKVCRTELFTPKMIES 140
Query: 422 QASAREAKVVELIEFLRRKDGEIVKFADVIFGAILNVLGALIFNKDVFDFEDKTDNNLGM 601
Q+ RE K E+++FLR K+GE+VK +V+FG ++N+ G LIF+KDVFD ED T ++ +
Sbjct: 141 QSEIREGKAREMVKFLRSKEGEVVKIVEVVFGTLVNIFGNLIFSKDVFDLEDPTGGSVEL 200
Query: 602 KGMIRQLMILASIPNLADLYPILGRSDLQGLRKASAVCVKRMNDSWAGIVKERRA-SNDQ 778
K + +L+ + + N AD +PI+G+ DL G R+A A ++++ D W +KERR +
Sbjct: 201 KEHLWKLLEMGNSTNPADYFPIMGKYDLFGQRRAVADVLQQIYDVWGINLKERRGMKGSE 260
Query: 779 SKNDFLQVLIDAGFTDAQIDAMLLETFGPGSDTSTSTIEWAMAELLRNPTKLIKVREELD 958
S NDF+ VL++AG D +I+A+L+E FG G++TS STIEWA+ EL + P + K+R EL
Sbjct: 261 SNNDFVDVLLNAGLEDQKINALLMELFGTGTETSASTIEWAITELTKKPLVVSKIRLELV 320
Query: 959 KVIGPNRAVKESDLPHLPYLHACVKETLRLHPPVTFLLPHRAIETCEVMNYTVPKGCQLM 1138
V+G N VKESDLPHLPYL A VKETLRLHPP LLP RA+ETC VMNYT+PK CQ+M
Sbjct: 321 NVVGDN-TVKESDLPHLPYLQAFVKETLRLHPPTPLLLPRRALETCTVMNYTIPKECQIM 379
Query: 1139 VNTYAIGRDPKTWPNPLSFTPERFLESDVDYQGNDFHYIPFGAGRRICPGLSLATRVVRL 1318
VN +AIGRDPKTW +PL+F PERFL SDVDY+GNDF IPFG GRRICPGL LA++ + L
Sbjct: 380 VNAWAIGRDPKTWDDPLNFKPERFLSSDVDYKGNDFELIPFGGGRRICPGLPLASQFISL 439
Query: 1319 ILGSLIHTFEWSLPNGMNPDELDMTDKFGLALLKDEPLLVIPKAR 1453
I+ +L+ FEWSLP GM+ EL M +KFGL L KD PLL++ KAR
Sbjct: 440 IVATLVQNFEWSLPQGMSTSELSMDEKFGLTLQKDPPLLIVLKAR 484
>BAF80448.1 corytuberine synthase [Coptis japonica var. dissecta]
Length = 486
Score = 517 bits (1332), Expect = e-177
Identities = 245/467 (52%), Positives = 339/467 (72%), Gaps = 3/467 (0%)
Frame = +2
Query: 65 KPSTKNLPPGPFAWPIIGTL---LPKLKKQPHIELSKLAKTYGPLMLLKFGVEPVVVASS 235
KP KNLPPGP WP+IG L + HI L+ +A+T+GP+M+L G +P V+AS+
Sbjct: 22 KPKYKNLPPGPHPWPLIGNLPILFTNTEVPLHITLANMARTHGPIMILWLGTQPTVMAST 81
Query: 236 HTAAMEVLKDQDRVLSGRFAPHSTRIKGYIEHSMVWADCTDYWKMIRKICRTELFSTKML 415
AAME+LK DR+ S R S R+K +I++S+VW+DCTDYWK++RKI RTE+FS KML
Sbjct: 82 AEAAMEILKTHDRIFSARHIRMSFRLKHHIKYSLVWSDCTDYWKLLRKIVRTEIFSPKML 141
Query: 416 DAQASAREAKVVELIEFLRRKDGEIVKFADVIFGAILNVLGALIFNKDVFDFEDKTDNNL 595
AQ+ RE KV ELI+FLR K+G++VK + +FG +LN+LG ++F+KDVF + D+TD
Sbjct: 142 QAQSHVREQKVAELIDFLRSKEGQVVKISQFVFGTLLNILGNVVFSKDVFVYGDETDKG- 200
Query: 596 GMKGMIRQLMILASIPNLADLYPILGRSDLQGLRKASAVCVKRMNDSWAGIVKERRASND 775
G++ +IR+++++ + PN+A+ YP L DLQGL+K R+ W G VKER+A+ +
Sbjct: 201 GIQNLIREMLMIGAEPNVAEFYPSLEELDLQGLKKKCDERFIRVMKMWEGTVKERKANRN 260
Query: 776 QSKNDFLQVLIDAGFTDAQIDAMLLETFGPGSDTSTSTIEWAMAELLRNPTKLIKVREEL 955
+ D L VL+ F DAQI+A+ LETFGPGS+TS++TIEW +AEL+++P ++ KVR+EL
Sbjct: 261 EESKDMLDVLLANDFNDAQINALFLETFGPGSETSSATIEWVIAELIKSPKEMAKVRKEL 320
Query: 956 DKVIGPNRAVKESDLPHLPYLHACVKETLRLHPPVTFLLPHRAIETCEVMNYTVPKGCQL 1135
++V+G + +KESDLP LPYL AC+KE +RLHP FLLP RA ETCEVM YT+PK Q+
Sbjct: 321 NEVVGTS-TIKESDLPQLPYLQACIKEAMRLHPAAPFLLPRRAAETCEVMGYTIPKNSQV 379
Query: 1136 MVNTYAIGRDPKTWPNPLSFTPERFLESDVDYQGNDFHYIPFGAGRRICPGLSLATRVVR 1315
+VN YAIGRDPK+W +P +F PERFLESDVD+ G + +IPFG+GRR C G+ LATR +
Sbjct: 380 LVNAYAIGRDPKSWKDPSTFWPERFLESDVDFHGAHYQFIPFGSGRRTCVGMPLATRTIP 439
Query: 1316 LILGSLIHTFEWSLPNGMNPDELDMTDKFGLALLKDEPLLVIPKARA 1456
LI+GSL+H +++ LP G P++L M + L L D L V+PKARA
Sbjct: 440 LIVGSLVHNYDFGLPGGNRPEDLKMNEMLSLTLAIDPSLCVVPKARA 486
>AKH61487.1 NMCH CYP80B1 P450 N-methylcoclaurine hydroxylase from Eschscholzia
californica [Expression vector pWCD2353]
Length = 490
Score = 509 bits (1312), Expect = e-174
Identities = 240/463 (51%), Positives = 335/463 (72%), Gaps = 4/463 (0%)
Frame = +2
Query: 77 KNLPPGPFAWPIIGTLLPKLKKQPHIELSKLAKTYGPLMLLKFGVEPVVVASSHTAAMEV 256
KNLPPGP WPI+G LL +L ++PH + ++LA+TYG + LK G E VVVAS+ +AA E+
Sbjct: 27 KNLPPGPKPWPIVGNLL-QLGEKPHAQFAELAQTYGDIFTLKMGTETVVVASTSSAASEI 85
Query: 257 LKDQDRVLSGRFAPHSTRIKGYIEHSMVWADCTDYWKMIRKICRTELFSTKMLDAQASAR 436
LK DR+LS R+ S R+KG++E+S+VW+DCT+ WK +RK+CRTELF+ KM+++QA R
Sbjct: 86 LKTHDRILSARYVFQSFRVKGHVENSIVWSDCTETWKNLRKVCRTELFTQKMIESQAHVR 145
Query: 437 EAKVVELIEFLRRKDGEIVKFADVIFGAILNVLGALIFNKDVFDFEDKTDNNLGMKGMIR 616
E K E++E+L +K GE VK +VIFG ++N+ G LIF++++F+ D + K +
Sbjct: 146 EKKCEEMVEYLMKKQGEEVKIVEVIFGTLVNIFGNLIFSQNIFELGDPNSGSSEFKEYLW 205
Query: 617 QLMILASIPNLADLYPILGRSDLQGLRKASAVCVKRMNDSWAGIVKERRASND----QSK 784
+++ L + N AD +P+LG+ DL G RK A C+K + W +++ER+ + QSK
Sbjct: 206 RMLELGNSTNPADYFPMLGKFDLFGQRKEVAECLKGIYAIWGAMLQERKLAKKVDGYQSK 265
Query: 785 NDFLQVLIDAGFTDAQIDAMLLETFGPGSDTSTSTIEWAMAELLRNPTKLIKVREELDKV 964
NDF+ V +D+G D QI+A+L+E FG G++TS STIEWAM EL +NP K+R EL V
Sbjct: 266 NDFVDVCLDSGLNDYQINALLMELFGAGTETSASTIEWAMTELTKNPKITAKLRSELQTV 325
Query: 965 IGPNRAVKESDLPHLPYLHACVKETLRLHPPVTFLLPHRAIETCEVMNYTVPKGCQLMVN 1144
+G R+VKESD P+LPYL A VKETLRLHPP LLP RA+ETC ++NYT+PK CQ+MVN
Sbjct: 326 VG-ERSVKESDFPNLPYLEATVKETLRLHPPTPLLLPRRALETCTILNYTIPKDCQIMVN 384
Query: 1145 TYAIGRDPKTWPNPLSFTPERFLESDVDYQGNDFHYIPFGAGRRICPGLSLATRVVRLIL 1324
+ IGRDPKTW +PL+F+PERFL S VD++GNDF IPFGAGRRICPGL +A + + L++
Sbjct: 385 AWGIGRDPKTWIDPLTFSPERFLNSSVDFRGNDFSLIPFGAGRRICPGLPIANQFIALLV 444
Query: 1325 GSLIHTFEWSLPNGMNPDELDMTDKFGLALLKDEPLLVIPKAR 1453
+ + +W LPNGM+ D L + +KFGL L K+ PL ++PK+R
Sbjct: 445 ATFVQNLDWCLPNGMSVDHLIVEEKFGLTLQKEPPLFIVPKSR 487
>AJD20229.1 corytuberine synthase [Sinopodophyllum hexandrum]
Length = 483
Score = 509 bits (1311), Expect = e-174
Identities = 247/466 (53%), Positives = 332/466 (71%), Gaps = 3/466 (0%)
Frame = +2
Query: 65 KPSTKNLPPGPFAWPIIGTLLPKLKKQP---HIELSKLAKTYGPLMLLKFGVEPVVVASS 235
KP +KNLPPGP WPIIG + P L H+ L+ +A+T+GP+M+L G +P VAS+
Sbjct: 21 KPRSKNLPPGPKPWPIIGNI-PALFSSAYPMHVALTNMARTHGPIMILWLGTQPTAVAST 79
Query: 236 HTAAMEVLKDQDRVLSGRFAPHSTRIKGYIEHSMVWADCTDYWKMIRKICRTELFSTKML 415
AAME+LK DR SGR S R+K +I++S+VWADC++YWK++RKI RTE+FS KML
Sbjct: 80 TEAAMEILKTHDRSFSGRAVRMSFRLKHHIKYSLVWADCSEYWKLLRKIVRTEIFSPKML 139
Query: 416 DAQASAREAKVVELIEFLRRKDGEIVKFADVIFGAILNVLGALIFNKDVFDFEDKTDNNL 595
Q RE KV EL+EFL+ K+G++VK + ++FG +LN+LG +IF+KDVF + +
Sbjct: 140 QVQEHVREQKVAELVEFLKGKEGQVVKISQLVFGTLLNILGNVIFSKDVFRYVGADGDK- 198
Query: 596 GMKGMIRQLMILASIPNLADLYPILGRSDLQGLRKASAVCVKRMNDSWAGIVKERRASND 775
M+ +I++++++ + PNLA+ +PI DLQGL+K + W G V+ER+ +
Sbjct: 199 -MQTLIKEMLMIGAAPNLAEFWPIFEEFDLQGLKKRCNQRFSEVMKMWKGTVEERKVKRN 257
Query: 776 QSKNDFLQVLIDAGFTDAQIDAMLLETFGPGSDTSTSTIEWAMAELLRNPTKLIKVREEL 955
+ D L VL+ F DAQI+A+ LETFGPGS+TS++T EWA+AEL++NP L KVR+EL
Sbjct: 258 EEPKDMLDVLLLNDFNDAQINAVFLETFGPGSETSSATSEWALAELIKNPHILAKVRQEL 317
Query: 956 DKVIGPNRAVKESDLPHLPYLHACVKETLRLHPPVTFLLPHRAIETCEVMNYTVPKGCQL 1135
D+V+G + VKESDLPHLPYL AC+KET+RLHP FLLPHRA+ETC VM YT+PK Q+
Sbjct: 318 DQVVGKS-TVKESDLPHLPYLQACIKETMRLHPAAPFLLPHRAVETCPVMGYTIPKDTQV 376
Query: 1136 MVNTYAIGRDPKTWPNPLSFTPERFLESDVDYQGNDFHYIPFGAGRRICPGLSLATRVVR 1315
+VN YAIGRDPKTW P +F PERFLESDVDY G F +IPFGAGRR C G+ LATR +
Sbjct: 377 LVNIYAIGRDPKTWKEPTTFKPERFLESDVDYYGKHFEFIPFGAGRRQCVGMPLATRTIP 436
Query: 1316 LILGSLIHTFEWSLPNGMNPDELDMTDKFGLALLKDEPLLVIPKAR 1453
LI+ +L+ T +WSLP+G P +L M + L+L D L VIPK+R
Sbjct: 437 LIVSNLVQTLDWSLPDGKLPQDLVMNESLSLSLALDPTLTVIPKSR 482
>O64899.1 RecName: Full=(S)-N-methylcoclaurine 3'-hydroxylase isozyme 1;
AltName: Full=Cytochrome P450 80B1 AAC39452.1
(S)-N-methylcoclaurine 3'-hydroxylase, partial
[Eschscholzia californica]
Length = 487
Score = 509 bits (1310), Expect = e-174
Identities = 238/463 (51%), Positives = 335/463 (72%), Gaps = 4/463 (0%)
Frame = +2
Query: 77 KNLPPGPFAWPIIGTLLPKLKKQPHIELSKLAKTYGPLMLLKFGVEPVVVASSHTAAMEV 256
KNLPPGP WPI+G LL +L ++PH + ++LA+TYG + LK G E VVVAS+ +AA E+
Sbjct: 26 KNLPPGPKPWPIVGNLL-QLGEKPHAQFAELAQTYGDIFTLKMGTETVVVASTSSAASEI 84
Query: 257 LKDQDRVLSGRFAPHSTRIKGYIEHSMVWADCTDYWKMIRKICRTELFSTKMLDAQASAR 436
LK DR+LS R+ S R+KG++E+S+VW+DCT+ WK +RK+CRTELF+ KM+++QA R
Sbjct: 85 LKTHDRILSARYVFQSFRVKGHVENSIVWSDCTETWKNLRKVCRTELFTQKMIESQAHVR 144
Query: 437 EAKVVELIEFLRRKDGEIVKFADVIFGAILNVLGALIFNKDVFDFEDKTDNNLGMKGMIR 616
E K E++E+L +K GE VK +VIFG ++N+ G LIF++++F+ D + K +
Sbjct: 145 EKKCEEMVEYLMKKQGEEVKIVEVIFGTLVNIFGNLIFSQNIFELGDPNSGSSEFKEYLW 204
Query: 617 QLMILASIPNLADLYPILGRSDLQGLRKASAVCVKRMNDSWAGIVKERRASND----QSK 784
+++ L + N AD +P+LG+ DL G RK A C+K + W +++ER+ + +SK
Sbjct: 205 RMLELGNSTNPADYFPMLGKFDLFGQRKEVAECLKGIYAIWGAMLQERKLAKKVDGYKSK 264
Query: 785 NDFLQVLIDAGFTDAQIDAMLLETFGPGSDTSTSTIEWAMAELLRNPTKLIKVREELDKV 964
NDF+ V +D+G D QI+A+L+E FG G++TS STIEWAM EL +NP K+R E+ V
Sbjct: 265 NDFVDVCLDSGLNDYQINALLMELFGAGTETSASTIEWAMTELTKNPKITAKIRSEIQTV 324
Query: 965 IGPNRAVKESDLPHLPYLHACVKETLRLHPPVTFLLPHRAIETCEVMNYTVPKGCQLMVN 1144
+G R+VKESD P+LPYL A VKETLRLHPP LLP RA+ETC ++NYT+PK CQ+MVN
Sbjct: 325 VG-ERSVKESDFPNLPYLEATVKETLRLHPPTPLLLPRRALETCTILNYTIPKDCQIMVN 383
Query: 1145 TYAIGRDPKTWPNPLSFTPERFLESDVDYQGNDFHYIPFGAGRRICPGLSLATRVVRLIL 1324
+ IGRDPKTW +PL+F+PERFL S VD++GNDF IPFGAGRRICPGL +A + + L++
Sbjct: 384 AWGIGRDPKTWTDPLTFSPERFLNSSVDFRGNDFSLIPFGAGRRICPGLPIANQFIALLV 443
Query: 1325 GSLIHTFEWSLPNGMNPDELDMTDKFGLALLKDEPLLVIPKAR 1453
+ + +W LPNGM+ D L + +KFGL L K+ PL ++PK+R
Sbjct: 444 ATFVQNLDWCLPNGMSVDHLIVEEKFGLTLQKEPPLFIVPKSR 486
>ACO90224.1 putative (S)-N-methylcoclaurine 3'-hydroxylase, partial [Papaver
bracteatum]
Length = 486
Score = 508 bits (1307), Expect = e-173
Identities = 240/467 (51%), Positives = 337/467 (72%), Gaps = 3/467 (0%)
Frame = +2
Query: 62 RKPSTKNLPPGPFAWPIIGTLLPKLKKQPHIELSKLAKTYGPLMLLKFGVEPVVVASSHT 241
R S K LPPGP WPI+G LL +L ++PH + ++LAKTYG L LK G E VVVAS+
Sbjct: 21 RDSSPKGLPPGPKPWPIVGNLL-QLGEKPHSQFAELAKTYGDLFTLKLGSETVVVASTPL 79
Query: 242 AAMEVLKDQDRVLSGRFAPHSTRIKGYIEHSMVWADCTDYWKMIRKICRTELFSTKMLDA 421
AA E+LK DRVLSGR+ S R+K ++E+S+VW++C + WK +RK+CR ELF+ KM+++
Sbjct: 80 AASEILKTHDRVLSGRYVFQSFRVKEHVENSIVWSECNETWKKLRKVCRAELFTQKMIES 139
Query: 422 QASAREAKVVELIEFLRRKDGEIVKFADVIFGAILNVLGALIFNKDVFDFEDKTDNNLGM 601
QA RE+K +E++EFL+R G VK +V+FG ++N+ G LIF++++F D++ ++ M
Sbjct: 140 QAEIRESKAMEMVEFLKRNQGSEVKIVEVVFGTLVNIFGNLIFSQNIFKLGDESSGSVEM 199
Query: 602 KGMIRQLMILASIPNLADLYPILGRSDLQGLRKASAVCVKRMNDSWAGIVKERRAS---N 772
K + +++ L + N AD +P LGR DL G RK A C++ + W ++KER+ + N
Sbjct: 200 KEHLWRMLELGNSTNPADYFPFLGRFDLFGQRKDVADCLQGIYSVWGAMLKERKIAKLHN 259
Query: 773 DQSKNDFLQVLIDAGFTDAQIDAMLLETFGPGSDTSTSTIEWAMAELLRNPTKLIKVREE 952
+ KNDF+++L+D+G D QI+A+L+E FG G++TS STIEWA++EL +NP +R E
Sbjct: 260 NSKKNDFVEILLDSGLDDQQINALLMEIFGAGTETSASTIEWALSELTKNPEVTANMRSE 319
Query: 953 LDKVIGPNRAVKESDLPHLPYLHACVKETLRLHPPVTFLLPHRAIETCEVMNYTVPKGCQ 1132
L V+G R VKESD+P++PYL A VKETLRLHP LLP RA+ETC+V+NYT+PK CQ
Sbjct: 320 LLSVVG-KRPVKESDIPNMPYLQAFVKETLRLHPATPLLLPRRALETCKVLNYTIPKECQ 378
Query: 1133 LMVNTYAIGRDPKTWPNPLSFTPERFLESDVDYQGNDFHYIPFGAGRRICPGLSLATRVV 1312
+MVN + IGRDPK W +PL F PERFL S +D++GNDF IPFGAGRRICPG+ LAT+ +
Sbjct: 379 IMVNAWGIGRDPKRWTDPLKFAPERFLNSSIDFKGNDFELIPFGAGRRICPGVPLATQFI 438
Query: 1313 RLILGSLIHTFEWSLPNGMNPDELDMTDKFGLALLKDEPLLVIPKAR 1453
LI+ +L+ F+W LP GM+P +L M +KFGL L K+ PL ++PK R
Sbjct: 439 SLIVPTLVQNFDWGLPKGMDPSQLIMEEKFGLTLQKEPPLYIVPKNR 485
>O64900.1 RecName: Full=(S)-N-methylcoclaurine 3'-hydroxylase isozyme 2;
AltName: Full=Cytochrome P450 80B2 AAC39453.1
(S)-N-methylcoclaurine 3'-hydroxylase [Eschscholzia
californica]
Length = 488
Score = 507 bits (1305), Expect = e-173
Identities = 239/463 (51%), Positives = 334/463 (72%), Gaps = 4/463 (0%)
Frame = +2
Query: 77 KNLPPGPFAWPIIGTLLPKLKKQPHIELSKLAKTYGPLMLLKFGVEPVVVASSHTAAMEV 256
KNLPPGP WPI+G LL +L ++PH + ++LA+TYG + LK G E VVVAS+ +AA E+
Sbjct: 27 KNLPPGPKPWPIVGNLL-QLGEKPHAQFAELAQTYGDIFTLKMGTETVVVASTSSAASEI 85
Query: 257 LKDQDRVLSGRFAPHSTRIKGYIEHSMVWADCTDYWKMIRKICRTELFSTKMLDAQASAR 436
LK DR+LS R+ S R+KG++E+S+VW+DCT+ WK +RK+CRTELF+ KM+++QA R
Sbjct: 86 LKTHDRILSARYVFQSFRVKGHVENSIVWSDCTETWKNLRKVCRTELFTQKMIESQAHVR 145
Query: 437 EAKVVELIEFLRRKDGEIVKFADVIFGAILNVLGALIFNKDVFDFEDKTDNNLGMKGMIR 616
E K E++E+L +K GE VK +VIFG ++N+ G LIF++++F+ + K +
Sbjct: 146 EKKCEEMVEYLMKKQGEEVKIVEVIFGTLVNIFGNLIFSQNIFELGXPNSGSSEFKEYLW 205
Query: 617 QLMILASIPNLADLYPILGRSDLQGLRKASAVCVKRMNDSWAGIVKERRASND----QSK 784
+++ L + N AD +P+LG+ DL G RK A C+K + W +++ER+ + QSK
Sbjct: 206 RMLELGNSTNPADYFPMLGKFDLFGQRKEVAECLKGIYAIWGAMLQERKLAKKVDGYQSK 265
Query: 785 NDFLQVLIDAGFTDAQIDAMLLETFGPGSDTSTSTIEWAMAELLRNPTKLIKVREELDKV 964
NDF+ V +D+G D QI+A+L+E FG G++TS STIEWAM EL +NP K+R EL V
Sbjct: 266 NDFVDVCLDSGLNDYQINALLMELFGAGTETSASTIEWAMTELTKNPKITAKLRSELQTV 325
Query: 965 IGPNRAVKESDLPHLPYLHACVKETLRLHPPVTFLLPHRAIETCEVMNYTVPKGCQLMVN 1144
+G R+VKESD P+LPYL A VKETLRLHPP LLP RA+ETC ++NYT+PK CQ+MVN
Sbjct: 326 VG-ERSVKESDFPNLPYLEATVKETLRLHPPTPLLLPRRALETCTILNYTIPKDCQIMVN 384
Query: 1145 TYAIGRDPKTWPNPLSFTPERFLESDVDYQGNDFHYIPFGAGRRICPGLSLATRVVRLIL 1324
+ IGRDPKTW +PL+F+PERFL S VD++GNDF IPFGAGRRICPGL +A + + L++
Sbjct: 385 AWGIGRDPKTWIDPLTFSPERFLNSSVDFRGNDFSLIPFGAGRRICPGLPIANQFIALLV 444
Query: 1325 GSLIHTFEWSLPNGMNPDELDMTDKFGLALLKDEPLLVIPKAR 1453
+ + +W LPNGM+ D L + +KFGL L K+ PL ++PK+R
Sbjct: 445 ATFVQNLDWCLPNGMSVDHLIVEEKFGLTLQKEPPLFIVPKSR 487
>AAU20767.1 (S)-N-methylcoclaurine 3'-hydroxylase [Thalictrum flavum subsp.
glaucum]
Length = 491
Score = 505 bits (1300), Expect = e-172
Identities = 241/459 (52%), Positives = 337/459 (73%)
Frame = +2
Query: 77 KNLPPGPFAWPIIGTLLPKLKKQPHIELSKLAKTYGPLMLLKFGVEPVVVASSHTAAMEV 256
K+LPPGP PI+G LL +L ++PH E +KLA+ YG L LK G + VVVASS AA E+
Sbjct: 28 KDLPPGPRPSPIVGNLL-QLGEKPHAEFAKLAEKYGELFTLKLGSQTVVVASSPAAAAEI 86
Query: 257 LKDQDRVLSGRFAPHSTRIKGYIEHSMVWADCTDYWKMIRKICRTELFSTKMLDAQASAR 436
LK +D++LSGR+ S R+ ++ +S+VW++C + WK++RK+CRTELFS KM+++QA R
Sbjct: 87 LKTRDKILSGRYVFQSFRVYEHVLNSIVWSECNENWKLLRKVCRTELFSPKMIESQAYIR 146
Query: 437 EAKVVELIEFLRRKDGEIVKFADVIFGAILNVLGALIFNKDVFDFEDKTDNNLGMKGMIR 616
EAK ++++ FLR+K+ + VK +V+F ++N+ G LIF+KDVFD ED T + +K +
Sbjct: 147 EAKALDMVRFLRKKENQEVKIVEVVFNTLVNIFGNLIFSKDVFDLEDPTGGSAELKEHLW 206
Query: 617 QLMILASIPNLADLYPILGRSDLQGLRKASAVCVKRMNDSWAGIVKERRASNDQSKNDFL 796
+L+ + + N AD +PI+G+ DL G R+ A +K++ D W ++KERR+ +NDF
Sbjct: 207 KLLDMGNSTNPADYFPIMGKFDLFGQRREVAKVLKQIYDVWGVMLKERRSITGHRENDFA 266
Query: 797 QVLIDAGFTDAQIDAMLLETFGPGSDTSTSTIEWAMAELLRNPTKLIKVREELDKVIGPN 976
VL++AG D +I+A+L+E FG G++T+ STIEWA+ EL N + K+R EL V+G +
Sbjct: 267 NVLLNAGLDDQKINALLMELFGAGTETTASTIEWAITELTNNLRVISKLRAELINVVG-H 325
Query: 977 RAVKESDLPHLPYLHACVKETLRLHPPVTFLLPHRAIETCEVMNYTVPKGCQLMVNTYAI 1156
+ VKES++PHLPYL A VKETLRLHPP LLP RA+ETC+VMNYT+PK CQ+MVN +AI
Sbjct: 326 KTVKESNIPHLPYLQAIVKETLRLHPPTPLLLPRRALETCKVMNYTIPKECQIMVNAWAI 385
Query: 1157 GRDPKTWPNPLSFTPERFLESDVDYQGNDFHYIPFGAGRRICPGLSLATRVVRLILGSLI 1336
GRDPKTW +PL+F PERF+ S VDY+GNDF IPFG GRRICPGL LA++ + LI+ +L+
Sbjct: 386 GRDPKTWDDPLTFKPERFMNSTVDYKGNDFELIPFGGGRRICPGLPLASQFLSLIVATLV 445
Query: 1337 HTFEWSLPNGMNPDELDMTDKFGLALLKDEPLLVIPKAR 1453
F+WS P GM P+E+ M +KFGL L KD PLL++ KAR
Sbjct: 446 QNFDWSFPQGMTPNEVPMDEKFGLPLQKDPPLLIVLKAR 484
>Q9SP06.1 RecName: Full=(S)-N-methylcoclaurine 3'-hydroxylase isozyme 1;
AltName: Full=Cytochrome P450 80B1; AltName:
Full=Cytochrome P450 80B3 AAF05621.1
(S)-N-methylcoclaurine 3'-hydroxylase, partial [Papaver
somniferum]
Length = 481
Score = 503 bits (1295), Expect = e-172
Identities = 237/467 (50%), Positives = 338/467 (72%), Gaps = 3/467 (0%)
Frame = +2
Query: 62 RKPSTKNLPPGPFAWPIIGTLLPKLKKQPHIELSKLAKTYGPLMLLKFGVEPVVVASSHT 241
R S K LPPGP WPI+G LL +L ++PH + ++LA+TYG L LK G E VVVAS+
Sbjct: 16 RDSSPKGLPPGPKPWPIVGNLL-QLGEKPHSQFAQLAETYGDLFSLKLGSETVVVASTPL 74
Query: 242 AAMEVLKDQDRVLSGRFAPHSTRIKGYIEHSMVWADCTDYWKMIRKICRTELFSTKMLDA 421
AA E+LK DRVLSGR+ S R+K ++E+S+VW++C + WK +RK+CRTELF+ KM+++
Sbjct: 75 AASEILKTHDRVLSGRYVFQSFRVKEHVENSIVWSECNETWKKLRKVCRTELFTQKMIES 134
Query: 422 QASAREAKVVELIEFLRRKDGEIVKFADVIFGAILNVLGALIFNKDVFDFEDKTDNNLGM 601
QA RE+K +E++E+L++ G VK A+V+FG ++N+ G LIF++++F D++ ++ M
Sbjct: 135 QAEVRESKAMEMVEYLKKNVGNEVKIAEVVFGTLVNIFGNLIFSQNIFKLGDESSGSVEM 194
Query: 602 KGMIRQLMILASIPNLADLYPILGRSDLQGLRKASAVCVKRMNDSWAGIVKERRAS---N 772
K + +++ L + N AD +P LG+ DL G K A C++ + W ++KER+ + N
Sbjct: 195 KEHLWRMLELGNSTNPADYFPFLGKFDLFGQSKDVADCLQGIYSVWGAMLKERKIAKQHN 254
Query: 773 DQSKNDFLQVLIDAGFTDAQIDAMLLETFGPGSDTSTSTIEWAMAELLRNPTKLIKVREE 952
+ KNDF+++L+D+G D QI+A+L+E FG G++TS STIEWA++EL +NP +R E
Sbjct: 255 NSKKNDFVEILLDSGLDDQQINALLMEIFGAGTETSASTIEWALSELTKNPQVTANMRLE 314
Query: 953 LDKVIGPNRAVKESDLPHLPYLHACVKETLRLHPPVTFLLPHRAIETCEVMNYTVPKGCQ 1132
L V+G R VKESD+P++PYL A VKETLRLHP LLP RA+ETC+V+NYT+PK CQ
Sbjct: 315 LLSVVG-KRPVKESDIPNMPYLQAFVKETLRLHPATPLLLPRRALETCKVLNYTIPKECQ 373
Query: 1133 LMVNTYAIGRDPKTWPNPLSFTPERFLESDVDYQGNDFHYIPFGAGRRICPGLSLATRVV 1312
+MVN + IGRDPK W +PL F+PERFL S +D++GNDF IPFGAGRRICPG+ LAT+ +
Sbjct: 374 IMVNAWGIGRDPKRWTDPLKFSPERFLNSSIDFKGNDFELIPFGAGRRICPGVPLATQFI 433
Query: 1313 RLILGSLIHTFEWSLPNGMNPDELDMTDKFGLALLKDEPLLVIPKAR 1453
LI+ SL+ F+W P GM+P +L M +KFGL L K+ PL ++PK R
Sbjct: 434 SLIVSSLVQNFDWGFPKGMDPSQLIMEEKFGLTLQKEPPLYIVPKTR 480
>AAF61400.1 (S)-N-methylcoclaurine 3'-hydroxylase, partial [Papaver somniferum]
Length = 481
Score = 501 bits (1290), Expect = e-171
Identities = 236/467 (50%), Positives = 338/467 (72%), Gaps = 3/467 (0%)
Frame = +2
Query: 62 RKPSTKNLPPGPFAWPIIGTLLPKLKKQPHIELSKLAKTYGPLMLLKFGVEPVVVASSHT 241
R S K LPPGP WPI+G LL +L ++PH + ++LA+TYG L LK G E VVVAS+
Sbjct: 16 RDSSPKGLPPGPKPWPIVGNLL-QLGEKPHSQFAQLAETYGDLFSLKLGSETVVVASTPL 74
Query: 242 AAMEVLKDQDRVLSGRFAPHSTRIKGYIEHSMVWADCTDYWKMIRKICRTELFSTKMLDA 421
AA E+LK DRVLSGR+ S R+K ++E+S+VW++C + WK +RK+CRT+LF+ KM+++
Sbjct: 75 AASEILKTHDRVLSGRYVFQSFRVKEHVENSIVWSECNETWKKLRKVCRTDLFTQKMIES 134
Query: 422 QASAREAKVVELIEFLRRKDGEIVKFADVIFGAILNVLGALIFNKDVFDFEDKTDNNLGM 601
QA RE+K +E++E+L++ G VK A+V+FG ++N+ G LIF++++F D++ ++ M
Sbjct: 135 QAEVRESKAMEMVEYLKKNVGNEVKIAEVVFGTLVNIFGNLIFSQNIFKLGDESSGSVEM 194
Query: 602 KGMIRQLMILASIPNLADLYPILGRSDLQGLRKASAVCVKRMNDSWAGIVKERRAS---N 772
K + +++ L + N AD +P LG+ DL G K A C++ + W ++KE + + N
Sbjct: 195 KEHLWRMLELGNSTNPADYFPFLGKFDLFGQSKDVADCLQGIYSVWGAMLKESKIAKQHN 254
Query: 773 DQSKNDFLQVLIDAGFTDAQIDAMLLETFGPGSDTSTSTIEWAMAELLRNPTKLIKVREE 952
+ KNDF+++L+D+G D QI+A+L+E FG G++TS STIEWA++EL +NP +R E
Sbjct: 255 NSKKNDFVEILLDSGLDDQQINALLMEIFGAGTETSASTIEWALSELTKNPQVTANMRLE 314
Query: 953 LDKVIGPNRAVKESDLPHLPYLHACVKETLRLHPPVTFLLPHRAIETCEVMNYTVPKGCQ 1132
L V+G R VKESD+P++PYL A VKETLRLHP LLP RA+ETC+V+NYT+PK CQ
Sbjct: 315 LLSVVG-KRPVKESDIPNMPYLQAFVKETLRLHPATPLLLPRRALETCKVLNYTIPKECQ 373
Query: 1133 LMVNTYAIGRDPKTWPNPLSFTPERFLESDVDYQGNDFHYIPFGAGRRICPGLSLATRVV 1312
+MVN + IGRDPK W +PL F+PERFL S +D++GNDF IPFGAGRRICPG+ LAT+ +
Sbjct: 374 IMVNAWGIGRDPKRWTDPLKFSPERFLNSSIDFKGNDFELIPFGAGRRICPGVPLATQFI 433
Query: 1313 RLILGSLIHTFEWSLPNGMNPDELDMTDKFGLALLKDEPLLVIPKAR 1453
LI+ SL+ F+W LP GM+P +L M +KFGL L K+ PL ++PK R
Sbjct: 434 SLIVSSLVQNFDWGLPKGMDPSQLIMEEKFGLTLQKEPPLYIVPKTR 480
>XP_002283461.2 PREDICTED: probable (S)-N-methylcoclaurine 3'-hydroxylase isozyme 2
isoform X2 [Vitis vinifera]
Length = 540
Score = 493 bits (1268), Expect = e-167
Identities = 243/462 (52%), Positives = 326/462 (70%), Gaps = 5/462 (1%)
Frame = +2
Query: 83 LPPGPFAWPIIGTLLPKLKKQPHIELSKLAKTYGPLMLLKFGVEPVVVASSHTAAMEVLK 262
LPPGP WPI+G LL L PHI L++ +++YGPL+ L+ G + +VVAS+ +AAME+LK
Sbjct: 81 LPPGPSPWPILGNLL-HLGNMPHISLARFSQSYGPLISLRLGSQILVVASTSSAAMEILK 139
Query: 263 DQDRVLSGRFAPHSTRIKG--YIEHSMVWA-DCTDYWKMIRKICRTELFSTKMLDAQASA 433
DRVLSGR+ PH+ K S+ WA +C D WK +R +CR ELFSTK++++QA
Sbjct: 140 THDRVLSGRYVPHAVPAKNSEINRMSLGWAVECNDAWKNLRTVCRAELFSTKVMESQAWV 199
Query: 434 REAKVVELIEFLRRKDGEIVKFADVIFGAILNVLGALIFNKDVFDFEDKTDNNLGMKGMI 613
E KV+E++ F+ K+GE++K +V+F +LN L ++ ++D FED + GMKG++
Sbjct: 200 GEKKVMEMVRFVSTKEGEVMKVGEVVFATVLNTLTTVLMSRDFISFEDDYKDG-GMKGLV 258
Query: 614 RQLMILASIPNLADLYPILGRSDLQGLRKASAVCVKRMNDSWAGIVKERR--ASNDQSKN 787
R++M+ + PNL D Y I DLQGL K + + R+ W +++ERR AS+D SK
Sbjct: 259 RKMMMAMAAPNLDDFYLIFSGLDLQGLNKKTKELIARICSMWESVIRERREGASDDPSKQ 318
Query: 788 DFLQVLIDAGFTDAQIDAMLLETFGPGSDTSTSTIEWAMAELLRNPTKLIKVREELDKVI 967
DFL +LI +G++D QI+ + +E G+DTS+ST+EWAMAEL+++P + KV EEL + I
Sbjct: 319 DFLNILIRSGYSDDQINQLFMELLTAGADTSSSTLEWAMAELIKSPESMKKVHEELAREI 378
Query: 968 GPNRAVKESDLPHLPYLHACVKETLRLHPPVTFLLPHRAIETCEVMNYTVPKGCQLMVNT 1147
N K SDLPHLPYL ACVKETLRLHP LLP RA +CEVMNYT+PK Q+ VN
Sbjct: 379 SDNLP-KASDLPHLPYLQACVKETLRLHPSAPLLLPRRASVSCEVMNYTIPKDSQIWVNA 437
Query: 1148 YAIGRDPKTWPNPLSFTPERFLESDVDYQGNDFHYIPFGAGRRICPGLSLATRVVRLILG 1327
+AIGRDP W +PL F PERFL S VD++GN+ +IPFGAGRRICPGL +A R++ LIL
Sbjct: 438 WAIGRDPMNWEDPLVFKPERFLNSAVDFKGNNLEFIPFGAGRRICPGLPMAARLLPLILA 497
Query: 1328 SLIHTFEWSLPNGMNPDELDMTDKFGLALLKDEPLLVIPKAR 1453
SL H F+WSLPNG PDELDM DKFG+AL K++PLL+IPK R
Sbjct: 498 SLTHFFDWSLPNGTTPDELDMNDKFGIALQKEQPLLIIPKVR 539
>XP_019072647.1 PREDICTED: probable (S)-N-methylcoclaurine 3'-hydroxylase isozyme 2
isoform X1 [Vitis vinifera]
Length = 541
Score = 488 bits (1256), Expect = e-165
Identities = 243/463 (52%), Positives = 326/463 (70%), Gaps = 6/463 (1%)
Frame = +2
Query: 83 LPPGPFAWPIIGTLLPKLKKQPHIELSKLAKTYGPLMLLKFGVEPVVVASSHTAAMEVLK 262
LPPGP WPI+G LL L PHI L++ +++YGPL+ L+ G + +VVAS+ +AAME+LK
Sbjct: 81 LPPGPSPWPILGNLL-HLGNMPHISLARFSQSYGPLISLRLGSQILVVASTSSAAMEILK 139
Query: 263 DQDRVLSGRFAPHSTRIKG--YIEHSMVWA-DCTDYWKMIRKICRTELFSTKMLDAQASA 433
DRVLSGR+ PH+ K S+ WA +C D WK +R +CR ELFSTK++++QA
Sbjct: 140 THDRVLSGRYVPHAVPAKNSEINRMSLGWAVECNDAWKNLRTVCRAELFSTKVMESQAWV 199
Query: 434 REAKVVELIEFLRRKDGEIVKFADVIFGAILNVLGALIFNKDVFDFEDKTDNNLGMKGMI 613
E KV+E++ F+ K+GE++K +V+F +LN L ++ ++D FED + GMKG++
Sbjct: 200 GEKKVMEMVRFVSTKEGEVMKVGEVVFATVLNTLTTVLMSRDFISFEDDYKDG-GMKGLV 258
Query: 614 RQLMILASIPNLADLYPILGRSDLQGLRKASAVCVKRMNDSWAGIVKERR--ASNDQSKN 787
R++M+ + PNL D Y I DLQGL K + + R+ W +++ERR AS+D SK
Sbjct: 259 RKMMMAMAAPNLDDFYLIFSGLDLQGLNKKTKELIARICSMWESVIRERREGASDDPSKQ 318
Query: 788 DFLQVLIDAGFTDAQIDAMLL-ETFGPGSDTSTSTIEWAMAELLRNPTKLIKVREELDKV 964
DFL +LI +G++D QI+ + + E G+DTS+ST+EWAMAEL+++P + KV EEL +
Sbjct: 319 DFLNILIRSGYSDDQINQLFMQELLTAGADTSSSTLEWAMAELIKSPESMKKVHEELARE 378
Query: 965 IGPNRAVKESDLPHLPYLHACVKETLRLHPPVTFLLPHRAIETCEVMNYTVPKGCQLMVN 1144
I N K SDLPHLPYL ACVKETLRLHP LLP RA +CEVMNYT+PK Q+ VN
Sbjct: 379 ISDNLP-KASDLPHLPYLQACVKETLRLHPSAPLLLPRRASVSCEVMNYTIPKDSQIWVN 437
Query: 1145 TYAIGRDPKTWPNPLSFTPERFLESDVDYQGNDFHYIPFGAGRRICPGLSLATRVVRLIL 1324
+AIGRDP W +PL F PERFL S VD++GN+ +IPFGAGRRICPGL +A R++ LIL
Sbjct: 438 AWAIGRDPMNWEDPLVFKPERFLNSAVDFKGNNLEFIPFGAGRRICPGLPMAARLLPLIL 497
Query: 1325 GSLIHTFEWSLPNGMNPDELDMTDKFGLALLKDEPLLVIPKAR 1453
SL H F+WSLPNG PDELDM DKFG+AL K++PLL+IPK R
Sbjct: 498 ASLTHFFDWSLPNGTTPDELDMNDKFGIALQKEQPLLIIPKVR 540
>XP_002283415.2 PREDICTED: probable (S)-N-methylcoclaurine 3'-hydroxylase isozyme 2
[Vitis vinifera]
Length = 540
Score = 487 bits (1253), Expect = e-164
Identities = 240/462 (51%), Positives = 325/462 (70%), Gaps = 5/462 (1%)
Frame = +2
Query: 83 LPPGPFAWPIIGTLLPKLKKQPHIELSKLAKTYGPLMLLKFGVEPVVVASSHTAAMEVLK 262
LPPGP WPI+G LL L PHI L++ +++YGPL+ L+ G + +VVAS+ +AAME+LK
Sbjct: 81 LPPGPSPWPILGNLL-HLGNMPHISLARFSQSYGPLISLRLGSQILVVASTSSAAMEILK 139
Query: 263 DQDRVLSGRFAPHSTRIKGYIEH--SMVWA-DCTDYWKMIRKICRTELFSTKMLDAQASA 433
DRVLSGR+ PH+ K + S+ WA +C WK +R +CR ELFSTK++++QA
Sbjct: 140 THDRVLSGRYVPHAVPAKNSEINPMSLGWAVECNGAWKNLRTVCRAELFSTKVMESQAWV 199
Query: 434 REAKVVELIEFLRRKDGEIVKFADVIFGAILNVLGALIFNKDVFDFEDKTDNNLGMKGMI 613
E KV+E++ F+ K+GE++K +V+F +LN L ++ ++D FED + GMKG++
Sbjct: 200 GEKKVMEMVRFVSTKEGEVMKVGEVVFATVLNTLTTVLMSRDFISFEDDNKDG-GMKGLV 258
Query: 614 RQLMILASIPNLADLYPILGRSDLQGLRKASAVCVKRMNDSWAGIVKERR--ASNDQSKN 787
R++++ + PNL D Y I DLQGL K + + R+ W +++ERR AS+D SK
Sbjct: 259 RKMVMAMAAPNLDDFYLIFSGLDLQGLNKKTKELIARICSMWESVIRERREGASDDPSKQ 318
Query: 788 DFLQVLIDAGFTDAQIDAMLLETFGPGSDTSTSTIEWAMAELLRNPTKLIKVREELDKVI 967
DFL +LI +G++D QI+ + +E G+DTS+ST+EWAMAEL+++P + KV EEL + I
Sbjct: 319 DFLNILIRSGYSDDQINQLFMELLTAGADTSSSTLEWAMAELIKSPESMKKVHEELAREI 378
Query: 968 GPNRAVKESDLPHLPYLHACVKETLRLHPPVTFLLPHRAIETCEVMNYTVPKGCQLMVNT 1147
N K SDLPHLPYL ACVKETLRLHP LLP RA +CEVMNYT+PK Q+ VN
Sbjct: 379 SDNLP-KASDLPHLPYLQACVKETLRLHPSAPLLLPRRASVSCEVMNYTIPKDSQIWVNA 437
Query: 1148 YAIGRDPKTWPNPLSFTPERFLESDVDYQGNDFHYIPFGAGRRICPGLSLATRVVRLILG 1327
+AIGRDP W +PL F PERFL S VD++GN+ +IPFGAGRRICPGL +A R++ LIL
Sbjct: 438 WAIGRDPMNWEDPLVFKPERFLNSAVDFKGNNLEFIPFGAGRRICPGLPMAARLLPLILA 497
Query: 1328 SLIHTFEWSLPNGMNPDELDMTDKFGLALLKDEPLLVIPKAR 1453
SL H F+WSLPNG PDELDM DKFG+ L K++PLL+IPK R
Sbjct: 498 SLTHFFDWSLPNGTTPDELDMNDKFGVTLQKEQPLLIIPKVR 539
>XP_019223612.1 PREDICTED: probable (S)-N-methylcoclaurine 3'-hydroxylase isozyme 2
[Nicotiana attenuata] OIT33933.1 cytochrome p450 76c2
[Nicotiana attenuata]
Length = 489
Score = 485 bits (1248), Expect = e-164
Identities = 244/467 (52%), Positives = 329/467 (70%), Gaps = 7/467 (1%)
Frame = +2
Query: 68 PSTKNLPPGPFAWPIIGTLLPKLKKQPHIELSKLAKTYGPLMLLKFGVEPVVVASSHTAA 247
P + NLPPGP WPI+G +L +L K PHI ++K AK GPL+ L+ G + VV+ASS +A
Sbjct: 25 PKSGNLPPGPRPWPILGNIL-QLGKNPHISMTKFAKINGPLISLRLGTQLVVIASSPDSA 83
Query: 248 MEVLKDQDRVLSGRFAPHSTRIKGYI--EHSMVWA-DCTDYWKMIRKICRTELFSTKMLD 418
E+LK QDR+LS R P K + +HS++W+ D +++WK +R CRT LFS K ++
Sbjct: 84 AEILKTQDRLLSARSVPRVAPYKLSVVDQHSLIWSSDLSNHWKSLRAFCRTHLFSAKAVE 143
Query: 419 AQASAREAKVVELIEFLRRKDGEIVKFADVIFGAILNVLGALIFNKDVFDFEDKTDNNLG 598
+QA RE KV E+IEFLR K G+ VK ++++F ILN LG L F KD+ D D N G
Sbjct: 144 SQADLREKKVFEMIEFLRSKKGKTVKISEIMFATILNTLGNLFFTKDLCDL-DYEGNTSG 202
Query: 599 MKGMIRQLMILASIPNLADLYPILGRSDLQGLRKASAVCVKRMNDSWAGIVKERRA--SN 772
+K +IR+ + L ++PN+++ YP L DLQGLRK + + ++ + WA IV E+R S
Sbjct: 203 IKHVIRKFVELGAMPNISEFYPFLDALDLQGLRKQTKIYQDQLFNIWAEIVNEKRQAISR 262
Query: 773 DQSKN--DFLQVLIDAGFTDAQIDAMLLETFGPGSDTSTSTIEWAMAELLRNPTKLIKVR 946
S N DFL ++ID+GF+D QI+ +L+E G+DT+TSTIEWAMAELLRN + K++
Sbjct: 263 GSSNNIQDFLDIMIDSGFSDLQINIILMELIAAGTDTTTSTIEWAMAELLRNKEVMHKLQ 322
Query: 947 EELDKVIGPNRAVKESDLPHLPYLHACVKETLRLHPPVTFLLPHRAIETCEVMNYTVPKG 1126
EL IG N ++ES++ LPYL ACVKETLR+HPP FL+P RA ETC++MNYT+PK
Sbjct: 323 AELRSKIGSNANIRESNISELPYLAACVKETLRIHPPTPFLIPRRAPETCKLMNYTIPKN 382
Query: 1127 CQLMVNTYAIGRDPKTWPNPLSFTPERFLESDVDYQGNDFHYIPFGAGRRICPGLSLATR 1306
+L VN +AIGRD KTW + LSF PERFL+S VD++G DF +IPFGAGRR CPGL A +
Sbjct: 383 SRLFVNVWAIGRDSKTWEDALSFRPERFLDSSVDFRGQDFEFIPFGAGRRTCPGLPFARQ 442
Query: 1307 VVRLILGSLIHTFEWSLPNGMNPDELDMTDKFGLALLKDEPLLVIPK 1447
V LIL SLIH FEWS+PNG +P +LDM +KFG+ L K++PLLV+P+
Sbjct: 443 EVHLILASLIHHFEWSIPNGEDPMQLDMEEKFGVTLQKEKPLLVVPR 489
>XP_009610421.1 PREDICTED: (S)-N-methylcoclaurine 3'-hydroxylase isozyme 1-like
[Nicotiana tomentosiformis]
Length = 489
Score = 483 bits (1244), Expect = e-164
Identities = 239/467 (51%), Positives = 329/467 (70%), Gaps = 7/467 (1%)
Frame = +2
Query: 68 PSTKNLPPGPFAWPIIGTLLPKLKKQPHIELSKLAKTYGPLMLLKFGVEPVVVASSHTAA 247
P + NLPPGP WPI+G +L +L K PHI +++ AK +GPL+ L+ G + VV+ASS +A
Sbjct: 25 PKSGNLPPGPRPWPILGNIL-QLGKNPHISMTQFAKIHGPLICLRLGTQLVVIASSPDSA 83
Query: 248 MEVLKDQDRVLSGRFAPHSTRIKGYI--EHSMVWA-DCTDYWKMIRKICRTELFSTKMLD 418
E+LK QDR+LS R P K + +HS+VW+ D T++WK +R CRT LFS K ++
Sbjct: 84 AEILKTQDRLLSARSVPRVAPYKLSVIDQHSIVWSSDLTNHWKSLRAFCRTHLFSAKAVE 143
Query: 419 AQASAREAKVVELIEFLRRKDGEIVKFADVIFGAILNVLGALIFNKDVFDFEDKTDNNLG 598
+QA RE KV E+IEFLR G+ VK ++++F ILN LG L F K++ D D N G
Sbjct: 144 SQADLREKKVFEMIEFLRSNKGKTVKISEILFATILNTLGNLFFTKNLCDL-DSEGNTSG 202
Query: 599 MKGMIRQLMILASIPNLADLYPILGRSDLQGLRKASAVCVKRMNDSWAGIVKERRAS--- 769
+K +IR+ + L ++PN+++ YP L DLQGLRK + + ++ WA +VKE+R +
Sbjct: 203 IKHVIRRFVELGAMPNISEFYPFLDALDLQGLRKLTNIYQDQLISIWAEVVKEKRQAISC 262
Query: 770 -NDQSKNDFLQVLIDAGFTDAQIDAMLLETFGPGSDTSTSTIEWAMAELLRNPTKLIKVR 946
+ DFL ++ID+GF+D QI+ +L+E G+DT+TSTIEWAMAELLRN + K++
Sbjct: 263 GSSNKNQDFLDIMIDSGFSDLQINIILMELIAAGTDTTTSTIEWAMAELLRNKKVMHKLQ 322
Query: 947 EELDKVIGPNRAVKESDLPHLPYLHACVKETLRLHPPVTFLLPHRAIETCEVMNYTVPKG 1126
E+ IG N ++ES++ LPYL ACVKETLR+HPP FL+P RA ETC++MN+T+PK
Sbjct: 323 AEIRSKIGSNANIRESNISELPYLAACVKETLRIHPPTPFLVPRRAPETCKLMNFTIPKN 382
Query: 1127 CQLMVNTYAIGRDPKTWPNPLSFTPERFLESDVDYQGNDFHYIPFGAGRRICPGLSLATR 1306
+L VN +AIGRD KTW + LSF PERFL+S VD++G DF +IPFGAGRRICPGL A +
Sbjct: 383 SRLFVNVWAIGRDSKTWEDALSFRPERFLDSSVDFRGQDFEFIPFGAGRRICPGLPFARQ 442
Query: 1307 VVRLILGSLIHTFEWSLPNGMNPDELDMTDKFGLALLKDEPLLVIPK 1447
V LIL SLIH FEWS+PNG +P +LDM +KFG+ L K++PLLV+P+
Sbjct: 443 EVHLILASLIHHFEWSVPNGEDPMQLDMGEKFGVTLQKEKPLLVVPR 489
>XP_006353352.1 PREDICTED: probable (S)-N-methylcoclaurine 3'-hydroxylase isozyme 2
[Solanum tuberosum]
Length = 486
Score = 483 bits (1243), Expect = e-164
Identities = 238/462 (51%), Positives = 333/462 (72%), Gaps = 3/462 (0%)
Frame = +2
Query: 68 PSTKNLPPGPFAWPIIGTLLPKLKKQPHIELSKLAKTYGPLMLLKFGVEPVVVASSHTAA 247
P + NLPPGP WP++G +L ++ K PHI L++ AK YGPL+ +K G + VVVASS +A
Sbjct: 26 PKSPNLPPGPRPWPLLGNIL-QIGKSPHISLAQFAKIYGPLISVKLGTQLVVVASSPDSA 84
Query: 248 MEVLKDQDRVLSGRFAPHSTRIKGYI--EHSMVWA-DCTDYWKMIRKICRTELFSTKMLD 418
E+LK QDR+LS R P + + +HS+V++ D +++WK +R CRT LFS K ++
Sbjct: 85 AEILKTQDRLLSVRSVPKVATYELSVIDQHSIVFSSDLSNHWKFLRAFCRTHLFSPKAVE 144
Query: 419 AQASAREAKVVELIEFLRRKDGEIVKFADVIFGAILNVLGALIFNKDVFDFEDKTDNNLG 598
+QA+ RE KV E+I FLR + GE VK ++++F ILN LG L F+KD+ D + +T N G
Sbjct: 145 SQAALREKKVSEMIHFLRSRKGETVKISEIMFATILNTLGNLFFSKDLCDLDYET-NTSG 203
Query: 599 MKGMIRQLMILASIPNLADLYPILGRSDLQGLRKASAVCVKRMNDSWAGIVKERRASNDQ 778
+K +IR+ + L ++PN+++ YP+ DLQGLRK + + ++ + W+ IVKE+R + +
Sbjct: 204 IKHVIRKFVELGAMPNISEFYPLFDALDLQGLRKQTEIYQNQLFNIWSDIVKEKRQAISR 263
Query: 779 SKNDFLQVLIDAGFTDAQIDAMLLETFGPGSDTSTSTIEWAMAELLRNPTKLIKVREELD 958
S +DFL V+ID+GF+D Q+D +L+E GSDT+TSTIEWAMAELLRN + K++ EL
Sbjct: 264 SSSDFLDVMIDSGFSDLQVDILLMELISAGSDTTTSTIEWAMAELLRNKGAMHKLQAELT 323
Query: 959 KVIGPNRAVKESDLPHLPYLHACVKETLRLHPPVTFLLPHRAIETCEVMNYTVPKGCQLM 1138
IG N + ES++ LPYL ACVKETLR+HPP FL+P RA ETC++M+YT+PK +L
Sbjct: 324 SKIGENDILTESNITELPYLAACVKETLRIHPPTPFLIPRRAPETCKIMDYTIPKNSRLF 383
Query: 1139 VNTYAIGRDPKTWPNPLSFTPERFLESDVDYQGNDFHYIPFGAGRRICPGLSLATRVVRL 1318
VN +AIGR+ TW + LSF PERFL+S+VD++G DF +IPFGAGRRICPGL A + V L
Sbjct: 384 VNVWAIGRNSNTWEDALSFRPERFLDSNVDFRGQDFEFIPFGAGRRICPGLPFARQEVHL 443
Query: 1319 ILGSLIHTFEWSLPNGMNPDELDMTDKFGLALLKDEPLLVIP 1444
IL SLIH FEWSLPNG +P ++DM +KFG+ L K++ LLV+P
Sbjct: 444 ILASLIHHFEWSLPNGEDPMQIDMKEKFGVTLQKEKSLLVVP 485
>XP_004234364.1 PREDICTED: probable (S)-N-methylcoclaurine 3'-hydroxylase isozyme 2
[Solanum lycopersicum]
Length = 486
Score = 479 bits (1232), Expect = e-162
Identities = 235/463 (50%), Positives = 330/463 (71%), Gaps = 3/463 (0%)
Frame = +2
Query: 68 PSTKNLPPGPFAWPIIGTLLPKLKKQPHIELSKLAKTYGPLMLLKFGVEPVVVASSHTAA 247
P + NLPPGP W ++G LL ++ K PH+ L+K A+ +GPL+ +K G + VVVASS +A
Sbjct: 26 PKSTNLPPGPRPWHLLGNLL-QIGKTPHVSLAKFAQIHGPLISVKLGTQLVVVASSPASA 84
Query: 248 MEVLKDQDRVLSGRFAPHSTRIKGYI--EHSMVWA-DCTDYWKMIRKICRTELFSTKMLD 418
E+LK QDR+LS R P + + +HS+V++ D ++ WK +R CRT LFS K ++
Sbjct: 85 AEILKSQDRLLSVRSVPKVATYELSVIDQHSIVFSSDLSNQWKFLRAFCRTHLFSPKAVE 144
Query: 419 AQASAREAKVVELIEFLRRKDGEIVKFADVIFGAILNVLGALIFNKDVFDFEDKTDNNLG 598
+QA+ RE KV E++ FLR + GE VK ++++FG ILN LG L F+KD+ D + +T N G
Sbjct: 145 SQAALREKKVSEMMNFLRSRKGETVKISEILFGTILNTLGNLFFSKDLCDLDYET-NTSG 203
Query: 599 MKGMIRQLMILASIPNLADLYPILGRSDLQGLRKASAVCVKRMNDSWAGIVKERRASNDQ 778
+K +IR+ + L ++PN+++ YP+ DLQGLRK + + R+ + W+ IVKE+R + +
Sbjct: 204 IKHVIRKFVELGAMPNISEFYPLFDALDLQGLRKQTEIYQNRLVNIWSEIVKEKRQAISR 263
Query: 779 SKNDFLQVLIDAGFTDAQIDAMLLETFGPGSDTSTSTIEWAMAELLRNPTKLIKVREELD 958
S +DFL +ID GF+D Q+D +L+E GSDT+TSTIEWAMAELLRN + K++ EL
Sbjct: 264 SSSDFLDAMIDNGFSDLQVDILLMELISAGSDTTTSTIEWAMAELLRNKGAMRKLKAELA 323
Query: 959 KVIGPNRAVKESDLPHLPYLHACVKETLRLHPPVTFLLPHRAIETCEVMNYTVPKGCQLM 1138
+G N + ES++ LPYL ACVKETLR+HPP FL+P RA ETC++M+YT+PK +L
Sbjct: 324 SKLGENDIITESNVSELPYLAACVKETLRIHPPTPFLIPRRAPETCKIMDYTIPKNSKLF 383
Query: 1139 VNTYAIGRDPKTWPNPLSFTPERFLESDVDYQGNDFHYIPFGAGRRICPGLSLATRVVRL 1318
VN +AIGRD TW + LSF PERFL S+VD++G DF +IPFGAGRRICPGL A + ++L
Sbjct: 384 VNAWAIGRDSNTWEDALSFRPERFLNSNVDFRGQDFEFIPFGAGRRICPGLGFARQEIQL 443
Query: 1319 ILGSLIHTFEWSLPNGMNPDELDMTDKFGLALLKDEPLLVIPK 1447
IL SLIH FEWSLPNG +P ++DM +KFG+ L K++ LL +PK
Sbjct: 444 ILASLIHYFEWSLPNGEDPMQIDMKEKFGVTLQKEKSLLAVPK 486