BLASTX 2.2.26 [Sep-21-2011]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= Lithospermum23_contig00004158
         (1711 letters)

Database: ./nr 
           115,041,592 sequences; 42,171,959,267 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

XP_015158492.1 PREDICTED: probable (S)-N-methylcoclaurine 3'-hyd...   519   e-177
XP_019262407.1 PREDICTED: (S)-N-methylcoclaurine 3'-hydroxylase ...   509   e-173
XP_011081970.1 PREDICTED: (S)-N-methylcoclaurine 3'-hydroxylase ...   495   e-167
XP_016477156.1 PREDICTED: (S)-N-methylcoclaurine 3'-hydroxylase ...   425   e-142
XP_011041604.1 PREDICTED: probable (S)-N-methylcoclaurine 3'-hyd...   425   e-140
XP_009623731.1 PREDICTED: (S)-N-methylcoclaurine 3'-hydroxylase ...   421   e-140
XP_012076022.1 PREDICTED: probable (S)-N-methylcoclaurine 3'-hyd...   410   e-134
KVI04737.1 hypothetical protein Ccrd_016945 [Cynara cardunculus ...   409   e-134
XP_002513347.1 PREDICTED: probable (S)-N-methylcoclaurine 3'-hyd...   406   e-133
XP_006353352.1 PREDICTED: probable (S)-N-methylcoclaurine 3'-hyd...   404   e-132
XP_012076024.1 PREDICTED: probable (S)-N-methylcoclaurine 3'-hyd...   403   e-132
XP_019223612.1 PREDICTED: probable (S)-N-methylcoclaurine 3'-hyd...   401   e-131
XP_002510830.1 PREDICTED: (S)-N-methylcoclaurine 3'-hydroxylase ...   400   e-131
XP_002274562.1 PREDICTED: probable (S)-N-methylcoclaurine 3'-hyd...   398   e-130
CAN62647.1 hypothetical protein VITISV_013219 [Vitis vinifera]        398   e-130
XP_009610421.1 PREDICTED: (S)-N-methylcoclaurine 3'-hydroxylase ...   396   e-129
XP_009757123.1 PREDICTED: probable (S)-N-methylcoclaurine 3'-hyd...   394   e-128
XP_016461059.1 PREDICTED: probable (S)-N-methylcoclaurine 3'-hyd...   394   e-128
XP_002318833.1 hypothetical protein POPTR_0012s13580g [Populus t...   394   e-128
XP_016564639.1 PREDICTED: probable (S)-N-methylcoclaurine 3'-hyd...   394   e-128

>XP_015158492.1 PREDICTED: probable (S)-N-methylcoclaurine 3'-hydroxylase isozyme 2
            [Solanum tuberosum]
          Length = 505

 Score =  519 bits (1337), Expect = e-177
 Identities = 264/472 (55%), Positives = 340/472 (72%), Gaps = 7/472 (1%)
 Frame = -1

Query: 1453 ENLPPGPWPWPIVGNIPHVLMSVIINIPPPQTVANLSKIYGPLLSLKLGSRLVILASSPE 1274
            +NLPP P+ WPI+GNIP+     II+  P   V  +S+  GPL+SLKLG++LV+  SSPE
Sbjct: 33   QNLPPSPFQWPIIGNIPNF----IISKKPHIIVTKISQTLGPLISLKLGNQLVVFGSSPE 88

Query: 1273 AAHAILNTHDRHLSGRYIAKATPIEAGELQRFSLLWSTERNSHSWKAIRDQWN-DLFSSK 1097
            +A  IL  HD+ LS RY  KATPI+  +L+R+SLLWSTE NSH WK+IR  W  +LFSSK
Sbjct: 89   SAIEILKNHDKQLSARYAPKATPIKESDLKRYSLLWSTECNSH-WKSIRVLWKTELFSSK 147

Query: 1096 AMDDYVKMREAKVAEMLHFLKRERLGQMVNIRDVVFTMVYNTLGNICFSKNMVNLDDDGE 917
            AM+ Y + R   V EM++FL  ++ G++V I D+VF  V+N LG ICFS NMV L+D  E
Sbjct: 148  AMESYAEKRGKGVVEMMNFLNFKQ-GKVVKIGDLVFGNVFNVLGEICFSINMVKLED--E 204

Query: 916  KKSSEVKKTIWGLMESGTTPILADFFPVFEGF-DVQGARRRTKGCIDRLYKVWEGIIQTR 740
            +  SE+K  IW  ME GTTPILADFFP+F+G  D+QG +++ K C+D L+K+WEGII+ R
Sbjct: 205  RVISEMKGNIWRFMEYGTTPILADFFPIFDGVVDIQGKKKKAKKCLDNLFKIWEGIIKER 264

Query: 739  RRGESTNNDGATKHGDFLHFMLANGWSDLQIKHMLLEVFPAATGNIPTTVEWAVAELIKN 560
            R           K+GDFL  MLANG+SD QI +MLLE+FPA TG + +T+EWA+AEL++N
Sbjct: 265  RESY------VEKNGDFLDLMLANGFSDDQINYMLLEIFPAGTGTLTSTIEWAMAELVRN 318

Query: 559  EEAMKKVRQEL-----STVTLSEGAILELPYLNACIKETLRLHPPIGFLPHCAQETCQVM 395
            +E MKK+  EL     ++ T+ E  I +LPYLNACIKE LRLHPPI FLPH A ETCQVM
Sbjct: 319  KEVMKKLNSELQNGSINSNTIQESTIFQLPYLNACIKEVLRLHPPIAFLPHYASETCQVM 378

Query: 394  GYTIPKDSLVIVNVWGMGHDKNIWGQDAVAFKPERFLDTNVDFKGQDYGYLPFGAGRRMC 215
             YTIPK  LV VN+W +GHD N+W  D  +FKPERFL+TN+D+KGQD+ +LPFGAGRRMC
Sbjct: 379  NYTIPKSCLVFVNLWAIGHDPNLW-DDPFSFKPERFLNTNIDYKGQDFEFLPFGAGRRMC 437

Query: 214  PGFPFAAKQVHLIVAALVSSFEWSVAGNRNGGEFHHTQLDMKEAYSVPIRKE 59
            PG PFA KQ+HLI+A LV  FEWS+  N +        LDM E Y+VP++++
Sbjct: 438  PGLPFATKQMHLILAYLVYHFEWSLPNNGD-----PLMLDMNEKYAVPLQRQ 484


>XP_019262407.1 PREDICTED: (S)-N-methylcoclaurine 3'-hydroxylase isozyme 1-like
            [Nicotiana attenuata] OIT37830.1 cytochrome p450 76c2
            [Nicotiana attenuata]
          Length = 499

 Score =  509 bits (1311), Expect = e-173
 Identities = 255/471 (54%), Positives = 343/471 (72%), Gaps = 5/471 (1%)
 Frame = -1

Query: 1453 ENLPPGPWPWPIVGNIPHVLMSVIINIPPPQTVANLSKIYGPLLSLKLGSRLVILASSPE 1274
            +NLPP P+ WP++GN+P+      I   P   V  +S+  GPL+SLKLG+++VI+ SSP+
Sbjct: 35   QNLPPAPFQWPLIGNMPN-----FIGKNPHIIVTKISQKLGPLISLKLGNQIVIIGSSPQ 89

Query: 1273 AAHAILNTHDRHLSGRYIAKATPIEAGELQRFSLLWSTERNSHSWKAIRDQWN-DLFSSK 1097
            +A  IL THD+ LS RY  KATPI+  +L+++SLLWSTE NSH WK+IR  W  +LFS+K
Sbjct: 90   SAVEILKTHDKQLSARYAPKATPIKESDLKKYSLLWSTECNSH-WKSIRVLWRTELFSNK 148

Query: 1096 AMDDYVKMREAKVAEMLHFLKRERLGQMVNIRDVVFTMVYNTLGNICFSKNMVNLDDDGE 917
            +M+ +   RE  V +M+ FL  ++ G++V I DVVF++V+N LGN CFSK+M+ L+D  E
Sbjct: 149  SMELFADKREKGVLDMVDFLVFKQ-GKVVKIGDVVFSVVFNILGNSCFSKDMIKLED--E 205

Query: 916  KKSSEVKKTIWGLMESGTTPILADFFPVFEGFDVQGARRRTKGCIDRLYKVWEGIIQTRR 737
            +   ++K+ IW  ME  TTPILADFFP F G D+ G +++ K C+D L+KVWEGI++ RR
Sbjct: 206  RVGCQMKENIWRFMEYSTTPILADFFPSFNGVDILGQKKKAKKCLDNLFKVWEGIVKERR 265

Query: 736  RGESTNNDGATKHGDFLHFMLANGWSDLQIKHMLLEVFPAATGNIPTTVEWAVAELIKNE 557
              ES +     K  DFL  ML+NG+SD QI +MLLE+FPA TG + +T+EWA+AEL++N+
Sbjct: 266  EEESLSGFDVKKQEDFLDLMLSNGFSDDQINYMLLEIFPAGTGTLTSTIEWAMAELLRNK 325

Query: 556  EAMKK----VRQELSTVTLSEGAILELPYLNACIKETLRLHPPIGFLPHCAQETCQVMGY 389
            E MKK    ++ E+++  + E  I +LPYLNACIKE LRLHPPI FLPH A ETCQVM Y
Sbjct: 326  EVMKKLYSELQNEINSNPIKESTIFQLPYLNACIKEVLRLHPPIAFLPHYASETCQVMNY 385

Query: 388  TIPKDSLVIVNVWGMGHDKNIWGQDAVAFKPERFLDTNVDFKGQDYGYLPFGAGRRMCPG 209
            TIPK+SLV VN+W +GHD   W +D  +FKPERFL++N+DFKGQD+ +LPFGAGRRMCPG
Sbjct: 386  TIPKNSLVFVNLWAIGHDPKHW-EDPFSFKPERFLNSNLDFKGQDFEFLPFGAGRRMCPG 444

Query: 208  FPFAAKQVHLIVAALVSSFEWSVAGNRNGGEFHHTQLDMKEAYSVPIRKEK 56
             PFA KQVHLI+A+LV  FEWS+    N G+     LDM E Y+VP+++EK
Sbjct: 445  LPFATKQVHLILASLVYHFEWSLP---NDGD--PLLLDMNEKYAVPLQREK 490


>XP_011081970.1 PREDICTED: (S)-N-methylcoclaurine 3'-hydroxylase isozyme 1-like
            [Sesamum indicum]
          Length = 509

 Score =  495 bits (1274), Expect = e-167
 Identities = 249/474 (52%), Positives = 340/474 (71%), Gaps = 9/474 (1%)
 Frame = -1

Query: 1450 NLPPGPWPWPIVGNIPHVLMSVIINIPPPQTVANLSKIYGPLLSLKLGSRLVILASSPEA 1271
            NLPPGP  WP++GNIP     + I   P   V+NL++I+GPL+SL+LG++++IL SSP+A
Sbjct: 45   NLPPGPRRWPVIGNIP-----LFIWKNPHVIVSNLARIHGPLMSLRLGTQVIILGSSPDA 99

Query: 1270 AHAILNTHDRHLSGRYIAKATPIEAGELQRFSLLWSTERNSHSWKAIRDQWN-DLFSSKA 1094
            A  IL THDR LSGR   KATPI+  +L++FSLLW+T+  S  WK+IR  W  +LFS+KA
Sbjct: 100  AKEILKTHDRDLSGRCAPKATPIKESDLKKFSLLWATDC-SPKWKSIRVLWKGELFSNKA 158

Query: 1093 MDDYVKMREAKVAEMLHFLKRERLGQMVNIRDVVFTMVYNTLGNICFSKNMVNLDDDGEK 914
            ++    +RE KVAEM+ +L R+  G++V I +VVF  VYNTLGN+CFS++++ L D  EK
Sbjct: 159  LEAQACLREKKVAEMVEYLGRKE-GEVVKIGEVVFAAVYNTLGNLCFSRDLIGLGD--EK 215

Query: 913  KSSEVKKTIWGLMESGTTPILADFFPVFEGF--DVQGARRRTKGCIDRLYKVWEGIIQTR 740
             + + K+  W  ME  TTP++ADFFPV +G   D QG +++   C+ +++ VW+ +I+ R
Sbjct: 216  MARDWKEVFWRFMECATTPLIADFFPVLDGLGLDFQGKKKQAAKCMKKMFGVWQELIRQR 275

Query: 739  RRGESTNNDGATKHGDFLHFMLANGWSDLQIKHMLLEVFPAATGNIPTTVEWAVAELIKN 560
            R       D + KHGDFL FML NG+ D+QI  MLLE+ PA  G +  T+EWA+AELIKN
Sbjct: 276  RESA----DDSKKHGDFLDFMLENGFLDIQILFMLLEILPAGAGTLVATIEWAMAELIKN 331

Query: 559  EEAMKKVRQELSTV------TLSEGAILELPYLNACIKETLRLHPPIGFLPHCAQETCQV 398
            +EAM K+ +EL T       ++ E  I +LPYLNAC+KETLRLHPPI FLPH AQ TC+V
Sbjct: 332  KEAMIKLEEELQTHKIVDSNSIRESHISQLPYLNACVKETLRLHPPIAFLPHSAQSTCEV 391

Query: 397  MGYTIPKDSLVIVNVWGMGHDKNIWGQDAVAFKPERFLDTNVDFKGQDYGYLPFGAGRRM 218
            M YT+P++SLV VN+W +GHD  +W +D  +F+PERFL++N+D+KGQD+  LPFGAGRRM
Sbjct: 392  MSYTVPENSLVFVNLWAIGHDPTVW-EDPFSFRPERFLNSNLDYKGQDFELLPFGAGRRM 450

Query: 217  CPGFPFAAKQVHLIVAALVSSFEWSVAGNRNGGEFHHTQLDMKEAYSVPIRKEK 56
            CPG PFA K+VHLI+A LV  F+WS+  NR+  +     LDM E Y+VP++KEK
Sbjct: 451  CPGLPFANKKVHLILAVLVGCFDWSLPDNRDPSD-----LDMNEKYAVPLQKEK 499


>XP_016477156.1 PREDICTED: (S)-N-methylcoclaurine 3'-hydroxylase isozyme 1-like
            [Nicotiana tabacum]
          Length = 403

 Score =  425 bits (1092), Expect = e-142
 Identities = 216/393 (54%), Positives = 286/393 (72%), Gaps = 6/393 (1%)
 Frame = -1

Query: 1216 KATPIEAGELQRFSLLWSTERNSHSWKAIRDQWN-DLFSSKAMDDYVKMREAKVAEMLHF 1040
            K   I+  +L+++SLLWSTE N+H WK+IR  W  +LFS KAM+ +   RE  V +M++F
Sbjct: 12   KLHQIKESDLKKYSLLWSTECNTH-WKSIRVLWRTELFSYKAMELFADEREKGVLDMVYF 70

Query: 1039 LKRERLGQMVNIRDVVFTMVYNTLGNICFSKNMVNLDDDGEKKSSEVKKTIWGLMESGTT 860
            L  ++ G +V I +VVF+ V+N LGNICFSK+M+ L+D  EK   ++K+ IW  ME  TT
Sbjct: 71   LGFKQ-GTVVKIGEVVFSTVFNVLGNICFSKDMIRLED--EKVGIKMKENIWRFMEYSTT 127

Query: 859  PILADFFPVFEGFDVQGARRR-TKGCIDRLYKVWEGIIQTRRRGESTNNDGATKHGDFLH 683
            PILAD F +F G D+QG +++  K C+D L+KVWEGI++ RR  ES +     K GDFL 
Sbjct: 128  PILADLFSIFNGVDIQGQKKKKAKECLDNLFKVWEGIVKERREEESLSGSDVKKQGDFLD 187

Query: 682  FMLANGWSDLQIKHMLLEVFPAATGNIPTTVEWAVAELIKNEEAMKKVRQEL----STVT 515
             MLANG+SD QI +MLLE+FPA TG + +T+EWA+AEL++N+E MK +  EL    ++  
Sbjct: 188  LMLANGFSDDQINYMLLEIFPAGTGTLTSTIEWAMAELLRNKEVMKVLYSELQNWINSNP 247

Query: 514  LSEGAILELPYLNACIKETLRLHPPIGFLPHCAQETCQVMGYTIPKDSLVIVNVWGMGHD 335
            + E  I +LPYLNACIKE LRLHPPI FLPH A ETCQVM YTIPK+SLV VN+W +G+D
Sbjct: 248  IKESTIFQLPYLNACIKEVLRLHPPIAFLPHYASETCQVMNYTIPKNSLVFVNLWAIGYD 307

Query: 334  KNIWGQDAVAFKPERFLDTNVDFKGQDYGYLPFGAGRRMCPGFPFAAKQVHLIVAALVSS 155
              +W +D  +FKPERFL++N+DFKGQD+ +LPFGAGRRMCPG PFA KQVHLI+A+LV  
Sbjct: 308  PKLW-EDPFSFKPERFLNSNLDFKGQDFEFLPFGAGRRMCPGLPFATKQVHLILASLVYH 366

Query: 154  FEWSVAGNRNGGEFHHTQLDMKEAYSVPIRKEK 56
            FEWS+    N G+     LDM E Y+VP+++EK
Sbjct: 367  FEWSLP---NDGD--PLILDMNETYAVPLQREK 394


>XP_011041604.1 PREDICTED: probable (S)-N-methylcoclaurine 3'-hydroxylase isozyme 2
            [Populus euphratica]
          Length = 492

 Score =  425 bits (1093), Expect = e-140
 Identities = 223/479 (46%), Positives = 318/479 (66%), Gaps = 6/479 (1%)
 Frame = -1

Query: 1474 SVPSRGGENLPPGPWPWPIVGNIPHVLMSVIINIPPPQTVANLSKIYGPLLSLKLGSRLV 1295
            S PS   ++LPPGP PWPI+GNI H          P  + AN +K +GPL+SLKLG +L+
Sbjct: 24   SSPSSKNQSLPPGPKPWPIIGNILH------FGKKPHISTANFAKTHGPLISLKLGKQLL 77

Query: 1294 ILASSPEAAHAILNTHDRHLSGRYIAKATPIEAGELQRFSLLWSTERNSHSWKAIRDQW- 1118
            I+ SS  AA  IL +HDR LS RY+ KA   E   L R S++W+T+  S  WK++R    
Sbjct: 78   IVGSSKRAATEILKSHDRLLSARYVFKAALFENHVLDRISIVWATQC-SDGWKSLRALCR 136

Query: 1117 NDLFSSKAMDDYVKMREAKVAEMLHFLKRERLGQMVNIRDVVFTMVYNTLGNICFSKNMV 938
            N+LFS+KA++    +RE K+ EM+ F+ R R G++V I +VV  +V+NT+ N+ FS +++
Sbjct: 137  NELFSAKAIESQAVLREKKMGEMVEFIGR-RKGEVVGIGEVVLAIVFNTIANLLFSVDLI 195

Query: 937  NLDDDGEKKSSEVKKTIWGLMESGTTPILADFFPVFEGFDVQGARRRTKGCIDRLYKVWE 758
             L+DDG   ++ +K  +W +M+ G TP ++DF+P+  G D QG +R+   C+++++ +W 
Sbjct: 196  GLEDDGA--ATGLKSLMWRMMKLGATPNISDFYPILGGIDPQGLKRKMAVCVNQMFGIWG 253

Query: 757  GIIQTRRRGESTNNDGATKHGDFLHFMLANGWSDLQIKHMLLEVFPAATGNIPTTVEWAV 578
              I+ RR  E   +DG     DFL   LANG+ DLQI  + LE+  A T    TTVEWA+
Sbjct: 254  KYIKERR--EKHVHDGP--RSDFLDVFLANGFEDLQINWLALELLSAGTDTTATTVEWAI 309

Query: 577  AELIKNEEAMKKVRQELS----TVTLSEGAILELPYLNACIKETLRLHPPIGFL-PHCAQ 413
            AEL+KN+E +KKV +E+     T +L E  + +LPYLNAC+ ETLRLHPP+ FL P  A 
Sbjct: 310  AELLKNKEVLKKVSEEIKRETDTNSLKESHVSQLPYLNACVNETLRLHPPVPFLIPRRAL 369

Query: 412  ETCQVMGYTIPKDSLVIVNVWGMGHDKNIWGQDAVAFKPERFLDTNVDFKGQDYGYLPFG 233
            ETC+VM YTIP+DS VIVNVW +G D ++W +D ++FKPERFL +++DFKG D+ +LPFG
Sbjct: 370  ETCKVMDYTIPRDSEVIVNVWAVGRDPSLW-EDPLSFKPERFLGSDLDFKGHDFEFLPFG 428

Query: 232  AGRRMCPGFPFAAKQVHLIVAALVSSFEWSVAGNRNGGEFHHTQLDMKEAYSVPIRKEK 56
            AGRR+CPG P AAKQVHLI+A L+  F+WS+    +        LDM E + + ++KE+
Sbjct: 429  AGRRICPGLPMAAKQVHLIIATLLYYFDWSLPNGED-----PATLDMSEKFGITLQKEQ 482


>XP_009623731.1 PREDICTED: (S)-N-methylcoclaurine 3'-hydroxylase isozyme 1-like
            [Nicotiana tomentosiformis]
          Length = 403

 Score =  421 bits (1083), Expect = e-140
 Identities = 213/393 (54%), Positives = 286/393 (72%), Gaps = 6/393 (1%)
 Frame = -1

Query: 1216 KATPIEAGELQRFSLLWSTERNSHSWKAIRDQWN-DLFSSKAMDDYVKMREAKVAEMLHF 1040
            K   I+  +L+++SLLWSTE N+H WK+IR  W  +LFS KAM+ +   RE  V +M++F
Sbjct: 12   KLHQIKESDLKKYSLLWSTECNTH-WKSIRVLWRTELFSYKAMELFADKREKGVLDMVYF 70

Query: 1039 LKRERLGQMVNIRDVVFTMVYNTLGNICFSKNMVNLDDDGEKKSSEVKKTIWGLMESGTT 860
            L  ++ G +V I +VVF+ V+N LGNICFSK+M+ L+D  EK   ++K+ IW  ME  TT
Sbjct: 71   LGFKQ-GTVVKIGEVVFSTVFNVLGNICFSKDMIRLED--EKVGIKMKENIWRFMEYSTT 127

Query: 859  PILADFFPVFEGFDVQGARRR-TKGCIDRLYKVWEGIIQTRRRGESTNNDGATKHGDFLH 683
            PILAD F +F G D+QG +++  K C+D L+KVWEGI++ RR  ES +     K GDFL 
Sbjct: 128  PILADLFSIFNGVDIQGQKKKKAKECLDNLFKVWEGIVKERREEESLSGSDVKKQGDFLD 187

Query: 682  FMLANGWSDLQIKHMLLEVFPAATGNIPTTVEWAVAELIKNEEAMK----KVRQELSTVT 515
             MLANG+SD QI +MLLE+FPA TG + +T+EWA+AEL++N+E MK    +++ E+++  
Sbjct: 188  LMLANGFSDDQINYMLLEIFPAGTGTLTSTIEWAMAELLRNKEVMKVLYSELQNEINSNP 247

Query: 514  LSEGAILELPYLNACIKETLRLHPPIGFLPHCAQETCQVMGYTIPKDSLVIVNVWGMGHD 335
            + E  I + PYLNACIKE L LHPPI FLPH A ETCQVM YTIPK+SLV VN+W +G+D
Sbjct: 248  IKESTIFQPPYLNACIKEVLGLHPPIAFLPHYASETCQVMNYTIPKNSLVFVNLWAIGYD 307

Query: 334  KNIWGQDAVAFKPERFLDTNVDFKGQDYGYLPFGAGRRMCPGFPFAAKQVHLIVAALVSS 155
              +W +D  +FKPERFL++N+DFKGQD+ +LPFGAGRRMCPG PFA KQVHLI+A+LV  
Sbjct: 308  PKLW-EDPFSFKPERFLNSNLDFKGQDFEFLPFGAGRRMCPGLPFATKQVHLILASLVYH 366

Query: 154  FEWSVAGNRNGGEFHHTQLDMKEAYSVPIRKEK 56
            FEWS+    N G+     LDM E Y+VP+++EK
Sbjct: 367  FEWSLP---NDGD--PLILDMNETYAVPLQREK 394


>XP_012076022.1 PREDICTED: probable (S)-N-methylcoclaurine 3'-hydroxylase isozyme 2
            [Jatropha curcas] XP_012092884.1 PREDICTED: probable
            (S)-N-methylcoclaurine 3'-hydroxylase isozyme 2 [Jatropha
            curcas]
          Length = 502

 Score =  410 bits (1054), Expect = e-134
 Identities = 213/468 (45%), Positives = 305/468 (65%), Gaps = 5/468 (1%)
 Frame = -1

Query: 1444 PPGPWPWPIVGNIPHVLMSVIINIPPPQTVANLSKIYGPLLSLKLGSRLVILASSPEAAH 1265
            PPGP PWPI+GNIPHV         P  ++A L+K++GP+ SL+LG +LV++ SSP  A 
Sbjct: 44   PPGPRPWPIIGNIPHVREK------PHISMAKLAKLHGPIFSLRLGYQLVVVGSSPAVAA 97

Query: 1264 AILNTHDRHLSGRYIAKATPIEAGELQRFSLLWSTERNSHSWKAIRD-QWNDLFSSKAMD 1088
             IL   DR LSGR++ KA P  + EL R +L+W+    S  WK++R     +LFS+KA++
Sbjct: 98   EILRKKDRFLSGRFVPKAIPRPSHELDRIALVWNPSC-SDQWKSLRALSRTELFSAKAIE 156

Query: 1087 DYVKMREAKVAEMLHFLKRERLGQMVNIRDVVFTMVYNTLGNICFSKNMVNLDDDGEKKS 908
                +RE KV+EM+ FL  ++ GQ+VN+ +VVF  V+N++ N+ FSK+ ++ +D  E+  
Sbjct: 157  SKAALREQKVSEMIEFLGIKQ-GQVVNVGEVVFATVFNSISNLLFSKDFISFED--EESV 213

Query: 907  SEVKKTIWGLMESGTTPILADFFPVFEGFDVQGARRRTKGCIDRLYKVWEGIIQTRRRGE 728
            S +K  +W LME G+ P LADF+P+F G D+QG R++   C+  ++ +WE  I+ RR   
Sbjct: 214  SGLKGLMWKLMELGSAPNLADFYPIFSGLDLQGLRKKMSKCLKEMFDIWEIFIKERRERH 273

Query: 727  STNNDGATKHGDFLHFMLANGWSDLQIKHMLLEVFPAATGNIPTTVEWAVAELIKNEEAM 548
            + N  G  K  DFL   ++NG+ D QI  ++ E+F A T    TTVEWA+AEL+KN+EAM
Sbjct: 274  ARN--GVVKE-DFLDVFISNGFDDEQINWLIHELFSAGTDTTTTTVEWAMAELLKNKEAM 330

Query: 547  KKVRQELSTV----TLSEGAILELPYLNACIKETLRLHPPIGFLPHCAQETCQVMGYTIP 380
             KV QEL       +++E  + + PYL ACIKET RLHPP  FL H   ETC+VM YTIP
Sbjct: 331  NKVCQELEREINKNSINESQVSQFPYLYACIKETFRLHPPAPFLGHQPLETCEVMNYTIP 390

Query: 379  KDSLVIVNVWGMGHDKNIWGQDAVAFKPERFLDTNVDFKGQDYGYLPFGAGRRMCPGFPF 200
            KDS +IVN+W +G D   W +D + FKPERFL++++D KG D+  LPF +GRRMCPG P 
Sbjct: 391  KDSQIIVNIWAVGRDPLAW-EDPLLFKPERFLESSLDLKGHDFELLPFSSGRRMCPGLPM 449

Query: 199  AAKQVHLIVAALVSSFEWSVAGNRNGGEFHHTQLDMKEAYSVPIRKEK 56
            A + + LI+A+L+  F+WS+ G  +        LDM + Y + ++KEK
Sbjct: 450  AIRFLPLILASLIHYFDWSLPGGED-----PAMLDMNDKYGITLQKEK 492


>KVI04737.1 hypothetical protein Ccrd_016945 [Cynara cardunculus var. scolymus]
          Length = 497

 Score =  409 bits (1052), Expect = e-134
 Identities = 211/476 (44%), Positives = 312/476 (65%), Gaps = 10/476 (2%)
 Frame = -1

Query: 1453 ENLPPGPWPWPIVGNIPHVLMSVIINIPPPQTVANLSKIYGPLLSLKLGSRLVILASSPE 1274
            +NLPPGP+ WPI+GN+PH+L        P   +  L++ YGPL S+KLG+ L ++ SSP 
Sbjct: 30   QNLPPGPYSWPIIGNLPHMLKG------PHIYLTQLARSYGPLCSVKLGTHLFVIGSSPM 83

Query: 1273 AAHAILNTHDRHLSGRYIAKATPIEAGELQRFSLLWSTERNSHSWKAIRDQWN-DLFSSK 1097
            AA  I+  HDR  + R++ KA       LQ +SL+W+TE + H WK +R     +LFS+K
Sbjct: 84   AATEIMRAHDRLPTYRWVPKAGQ---DGLQEYSLIWATECSQH-WKLLRCLCRTELFSAK 139

Query: 1096 AMDDYVKMREAKVAEMLHFLKRERLGQMVNIRDVVFTMVYNTLGNICFSKNMVNL---DD 926
             ++    +RE  V  M+ FLKR++ G +VN+R++VF +  N LG ICFSK+ + L   DD
Sbjct: 140  GLESQSSLREKNVDSMVGFLKRKQ-GNLVNVREMVFAVTVNILGTICFSKDFIELELSDD 198

Query: 925  DGEKKSSEVKKTIWGLMESGTTPILADFFPVFEGFDVQGARRRTKGCIDRLYKVWEGIIQ 746
            +   +S  +K  ++ LM+ GTTP +ADF+P FEG D QG +++T   +D  + VW  II+
Sbjct: 199  EKGTRSRGLKGALYRLMKLGTTPNVADFYPKFEGLDPQGLKKKTSEAMDEAFNVWADIIK 258

Query: 745  TRRRGESTNNDGATKHGDFLHFMLANGWSDLQIKHMLLEVFPAATGNIPTTVEWAVAELI 566
             RR  +   N       DFL  M+  G+SDLQI  + +E+F   T +  +T+EWA+AEL+
Sbjct: 259  ERR--DIRENQKGLIEQDFLDTMIKCGFSDLQINQLTVELFSGGTHSTASTIEWALAELL 316

Query: 565  KNEEAMKKVRQEL-----STVTLSEGAILELPYLNACIKETLRLHPPIGFL-PHCAQETC 404
            KN++AM  +R+EL     ST  + E  + +LPYL+AC+KETLRLHPP   L P    ++C
Sbjct: 317  KNKQAMFAMREELVNKLGSTTCIKESQVSQLPYLHACVKETLRLHPPAPLLHPQAILQSC 376

Query: 403  QVMGYTIPKDSLVIVNVWGMGHDKNIWGQDAVAFKPERFLDTNVDFKGQDYGYLPFGAGR 224
            ++M YT+PK+S +I+NVW MG D N+W  D +AFKPERFL++NVDFKGQD+ +LPFG GR
Sbjct: 377  EIMNYTVPKNSQLIINVWAMGRDPNLW-DDPLAFKPERFLNSNVDFKGQDFKFLPFGVGR 435

Query: 223  RMCPGFPFAAKQVHLIVAALVSSFEWSVAGNRNGGEFHHTQLDMKEAYSVPIRKEK 56
            RMCPG+P+A KQ+HL++A+LV +F+W +  N        ++LDM E + +  ++++
Sbjct: 436  RMCPGYPYAIKQIHLMLASLVQNFDWFLPSNIE----DLSKLDMSENFGIISQRKR 487


>XP_002513347.1 PREDICTED: probable (S)-N-methylcoclaurine 3'-hydroxylase isozyme 2
            [Ricinus communis] EEF48750.1 (S)-N-methylcoclaurine
            3'-hydroxylase isozyme, putative [Ricinus communis]
          Length = 496

 Score =  406 bits (1043), Expect = e-133
 Identities = 218/470 (46%), Positives = 310/470 (65%), Gaps = 6/470 (1%)
 Frame = -1

Query: 1447 LPPGPWPWPIVGNIPHVLMSVIINIPPPQTVANLSKIYGPLLSLKLGSRLVILASSPEAA 1268
            LPPGP  WPI+GNI  V  +      P  ++AN +K++GPL+SL+LG+R+V++ASSP AA
Sbjct: 37   LPPGPRQWPILGNILQVGKN------PHISMANYAKVHGPLISLRLGTRVVVVASSPTAA 90

Query: 1267 HAILNTHDRHLSGRYIAKATPIEAGELQRFSLLWSTERNSHSWKAIRDQW-NDLFSSKAM 1091
              IL THDR LSGRYI   TP E   L R +L+W+    S  WK +R    ++LFS+KA+
Sbjct: 91   AEILKTHDRLLSGRYIPATTPYEDNVLDRIALVWNPSC-SDQWKFLRAMCRSELFSAKAI 149

Query: 1090 DDYVKMREAKVAEMLHFLKRERLGQMVNIRDVVFTMVYNTLGNICFSKNMVNLDDDGEKK 911
            +    +RE K+ EML FL  ++ GQ+VNI +VVFT  +NT+ N+ FSK++++ +D G   
Sbjct: 150  ESQATLREKKLTEMLDFLTSKQ-GQIVNIGEVVFTTAFNTISNLLFSKDLLSFEDQGN-- 206

Query: 910  SSEVKKTIWGLMESGTTPILADFFPVFEGFDVQGARRRTKGCIDRLYKVWEGIIQTRRRG 731
            + E+K  I  LME  T P +ADF+PV    D QG +R+ K C++R++ VW+  I+ RR  
Sbjct: 207  AGELKTLISTLMELATCPNIADFYPVLTKLDPQGIKRKMKNCLERMFGVWDIYIKERRER 266

Query: 730  ESTNNDGATKHGDFLHFMLANGWSDLQIKHMLLEVFPAATGNIPTTVEWAVAELIKNEEA 551
               +     +  DFL   L+NG+ D QI  +LLE+F A      TTVEWA+AEL+K    
Sbjct: 267  HVKD----ARKTDFLDVFLSNGFDDHQINWLLLELFSAGADTTTTTVEWAMAELLKEITV 322

Query: 550  MKKVRQELSTVT----LSEGAILELPYLNACIKETLRLHPPIGFL-PHCAQETCQVMGYT 386
            ++KVR+EL T      + E  I +L YLNAC+KETLRLHPP+ FL P  A E C+VM YT
Sbjct: 323  LEKVREELETEIGKDMIRESHIPQLKYLNACVKETLRLHPPVPFLIPRRAPEACEVMNYT 382

Query: 385  IPKDSLVIVNVWGMGHDKNIWGQDAVAFKPERFLDTNVDFKGQDYGYLPFGAGRRMCPGF 206
            IPK S +IVNVW +G D + W +D ++++PERFLD+N+DFKG ++ +LPFG+GRR+CPG 
Sbjct: 383  IPKHSQIIVNVWAIGRDPSAW-EDPLSYRPERFLDSNLDFKGHNFEFLPFGSGRRICPGL 441

Query: 205  PFAAKQVHLIVAALVSSFEWSVAGNRNGGEFHHTQLDMKEAYSVPIRKEK 56
            P   +Q+ LI+A+LV  F+WS+   +NG +     LDM + +S+ + KE+
Sbjct: 442  PMGTRQLPLILASLVHCFDWSL---QNGDD--PAMLDMNDKFSITLEKEQ 486


>XP_006353352.1 PREDICTED: probable (S)-N-methylcoclaurine 3'-hydroxylase isozyme 2
            [Solanum tuberosum]
          Length = 486

 Score =  404 bits (1037), Expect = e-132
 Identities = 210/472 (44%), Positives = 320/472 (67%), Gaps = 7/472 (1%)
 Frame = -1

Query: 1450 NLPPGPWPWPIVGNIPHVLMSVIINIPPPQTVANLSKIYGPLLSLKLGSRLVILASSPEA 1271
            NLPPGP PWP++GNI  +  S      P  ++A  +KIYGPL+S+KLG++LV++ASSP++
Sbjct: 30   NLPPGPRPWPLLGNILQIGKS------PHISLAQFAKIYGPLISVKLGTQLVVVASSPDS 83

Query: 1270 AHAILNTHDRHLSGRYIAKATPIEAGELQRFSLLWSTERNSHSWKAIRDQWND-LFSSKA 1094
            A  IL T DR LS R + K    E   + + S+++S++ ++H WK +R      LFS KA
Sbjct: 84   AAEILKTQDRLLSVRSVPKVATYELSVIDQHSIVFSSDLSNH-WKFLRAFCRTHLFSPKA 142

Query: 1093 MDDYVKMREAKVAEMLHFLKRERLGQMVNIRDVVFTMVYNTLGNICFSKNMVNLDDDGEK 914
            ++    +RE KV+EM+HFL R R G+ V I +++F  + NTLGN+ FSK++ +LD   E 
Sbjct: 143  VESQAALREKKVSEMIHFL-RSRKGETVKISEIMFATILNTLGNLFFSKDLCDLDY--ET 199

Query: 913  KSSEVKKTIWGLMESGTTPILADFFPVFEGFDVQGARRRTKGCIDRLYKVWEGIIQTRRR 734
             +S +K  I   +E G  P +++F+P+F+  D+QG R++T+   ++L+ +W  I++ +R+
Sbjct: 200  NTSGIKHVIRKFVELGAMPNISEFYPLFDALDLQGLRKQTEIYQNQLFNIWSDIVKEKRQ 259

Query: 733  GESTNNDGATKHGDFLHFMLANGWSDLQIKHMLLEVFPAATGNIPTTVEWAVAELIKNEE 554
              S ++       DFL  M+ +G+SDLQ+  +L+E+  A +    +T+EWA+AEL++N+ 
Sbjct: 260  AISRSSS------DFLDVMIDSGFSDLQVDILLMELISAGSDTTTSTIEWAMAELLRNKG 313

Query: 553  AMKKVRQELSTVT-----LSEGAILELPYLNACIKETLRLHPPIGFL-PHCAQETCQVMG 392
            AM K++ EL++       L+E  I ELPYL AC+KETLR+HPP  FL P  A ETC++M 
Sbjct: 314  AMHKLQAELTSKIGENDILTESNITELPYLAACVKETLRIHPPTPFLIPRRAPETCKIMD 373

Query: 391  YTIPKDSLVIVNVWGMGHDKNIWGQDAVAFKPERFLDTNVDFKGQDYGYLPFGAGRRMCP 212
            YTIPK+S + VNVW +G + N W +DA++F+PERFLD+NVDF+GQD+ ++PFGAGRR+CP
Sbjct: 374  YTIPKNSRLFVNVWAIGRNSNTW-EDALSFRPERFLDSNVDFRGQDFEFIPFGAGRRICP 432

Query: 211  GFPFAAKQVHLIVAALVSSFEWSVAGNRNGGEFHHTQLDMKEAYSVPIRKEK 56
            G PFA ++VHLI+A+L+  FEWS+    +       Q+DMKE + V ++KEK
Sbjct: 433  GLPFARQEVHLILASLIHHFEWSLPNGED-----PMQIDMKEKFGVTLQKEK 479


>XP_012076024.1 PREDICTED: probable (S)-N-methylcoclaurine 3'-hydroxylase isozyme 2
            [Jatropha curcas]
          Length = 502

 Score =  403 bits (1036), Expect = e-132
 Identities = 206/469 (43%), Positives = 308/469 (65%), Gaps = 6/469 (1%)
 Frame = -1

Query: 1444 PPGPWPWPIVGNIPHVLMSVIINIPPPQTVANLSKIYGPLLSLKLGSRLVILASSPEAAH 1265
            PPGP PWPI+GNIPHV         P  ++A L+K++GP+ SL+LG +LV++ SSP  A 
Sbjct: 44   PPGPRPWPIIGNIPHVREK------PHISMAKLAKLHGPIFSLRLGYQLVVVGSSPAVAA 97

Query: 1264 AILNTHDRHLSGRYIAKATPIEAGELQRFSLLWSTERNSHSWKAIRD-QWNDLFSSKAMD 1088
             IL   DR LSGR++ KA P  + EL R +L+W+    S  WK++R     +LFS+KA++
Sbjct: 98   EILRKKDRFLSGRFVPKAIPRPSHELDRIALVWNPSC-SDQWKSLRALSRTELFSAKAIE 156

Query: 1087 DYVKMREAKVAEMLHFLKRERLGQMVNIRDVVFTMVYNTLGNICFSKNMVNLDDDGEKKS 908
                +RE KV+EM+ FL  ++ GQ+VN+ +VVF  V+N++ N+ FSK+ ++ +D  E+  
Sbjct: 157  SKAALREQKVSEMIEFLGIKQ-GQVVNVGEVVFATVFNSISNLLFSKDFISFED--EESV 213

Query: 907  SEVKKTIWGLMESGTTPILADFFPVFEGFDVQGARRRTKGCIDRLYKVWEGIIQTRRRGE 728
            S +K  +W LME G+ P LADF+P+F G D+QG R++   C+  ++ +WE  I+ RR   
Sbjct: 214  SGLKGLMWKLMELGSAPNLADFYPIFSGLDLQGLRKKMSKCLKEMFDIWEIFIKERRERH 273

Query: 727  STNNDGATKHGDFLHFMLANGWSDLQIKHMLLEVFPAATGNIPTTVEWAVAELIKNEEAM 548
            + N  G  K  DFL   ++NG+ D QI  ++ E+F A      TTVEWA+AEL+KN++AM
Sbjct: 274  ARN--GVVKE-DFLDVFISNGFDDEQINWLIHELFSAGVDTTTTTVEWAIAELLKNKQAM 330

Query: 547  KKVRQELSTVT----LSEGAILELPYLNACIKETLRLHPPIGFL-PHCAQETCQVMGYTI 383
            K ++QEL T      + E  + +L YLNAC+KETLRLHPP  FL PHCA E C++M + +
Sbjct: 331  KTLQQELETEINRNPIQESQVSQLLYLNACVKETLRLHPPAPFLLPHCATEACELMNFVV 390

Query: 382  PKDSLVIVNVWGMGHDKNIWGQDAVAFKPERFLDTNVDFKGQDYGYLPFGAGRRMCPGFP 203
            PK++ V+VNVW +  D  IW +D+  FKPERFL + +DFK Q++ +LPFG+GRR+CPG P
Sbjct: 391  PKNTRVLVNVWAIARDPLIW-EDSELFKPERFLHSGLDFKSQNFDFLPFGSGRRICPGLP 449

Query: 202  FAAKQVHLIVAALVSSFEWSVAGNRNGGEFHHTQLDMKEAYSVPIRKEK 56
             A +Q+ +I+A+L+  F+WS+    +        LDM + + + ++KE+
Sbjct: 450  MAIRQLPMILASLIHHFDWSLPNGED-----PALLDMTDKFGITLQKEQ 493


>XP_019223612.1 PREDICTED: probable (S)-N-methylcoclaurine 3'-hydroxylase isozyme 2
            [Nicotiana attenuata] OIT33933.1 cytochrome p450 76c2
            [Nicotiana attenuata]
          Length = 489

 Score =  401 bits (1031), Expect = e-131
 Identities = 210/479 (43%), Positives = 316/479 (65%), Gaps = 7/479 (1%)
 Frame = -1

Query: 1471 VPSRGGENLPPGPWPWPIVGNIPHVLMSVIINIPPPQTVANLSKIYGPLLSLKLGSRLVI 1292
            +P  G  NLPPGP PWPI+GNI      + +   P  ++   +KI GPL+SL+LG++LV+
Sbjct: 24   IPKSG--NLPPGPRPWPILGNI------LQLGKNPHISMTKFAKINGPLISLRLGTQLVV 75

Query: 1291 LASSPEAAHAILNTHDRHLSGRYIAKATPIEAGELQRFSLLWSTERNSHSWKAIRDQWND 1112
            +ASSP++A  IL T DR LS R + +  P +   + + SL+WS++ ++H WK++R     
Sbjct: 76   IASSPDSAAEILKTQDRLLSARSVPRVAPYKLSVVDQHSLIWSSDLSNH-WKSLRAFCRT 134

Query: 1111 -LFSSKAMDDYVKMREAKVAEMLHFLKRERLGQMVNIRDVVFTMVYNTLGNICFSKNMVN 935
             LFS+KA++    +RE KV EM+ FL R + G+ V I +++F  + NTLGN+ F+K++ +
Sbjct: 135  HLFSAKAVESQADLREKKVFEMIEFL-RSKKGKTVKISEIMFATILNTLGNLFFTKDLCD 193

Query: 934  LDDDGEKKSSEVKKTIWGLMESGTTPILADFFPVFEGFDVQGARRRTKGCIDRLYKVWEG 755
            LD +G   +S +K  I   +E G  P +++F+P  +  D+QG R++TK   D+L+ +W  
Sbjct: 194  LDYEGN--TSGIKHVIRKFVELGAMPNISEFYPFLDALDLQGLRKQTKIYQDQLFNIWAE 251

Query: 754  IIQTRRRGESTNNDGATKHGDFLHFMLANGWSDLQIKHMLLEVFPAATGNIPTTVEWAVA 575
            I+  +R+  S  +    +  DFL  M+ +G+SDLQI  +L+E+  A T    +T+EWA+A
Sbjct: 252  IVNEKRQAISRGSSNNIQ--DFLDIMIDSGFSDLQINIILMELIAAGTDTTTSTIEWAMA 309

Query: 574  ELIKNEEAMKKVRQEL-----STVTLSEGAILELPYLNACIKETLRLHPPIGFL-PHCAQ 413
            EL++N+E M K++ EL     S   + E  I ELPYL AC+KETLR+HPP  FL P  A 
Sbjct: 310  ELLRNKEVMHKLQAELRSKIGSNANIRESNISELPYLAACVKETLRIHPPTPFLIPRRAP 369

Query: 412  ETCQVMGYTIPKDSLVIVNVWGMGHDKNIWGQDAVAFKPERFLDTNVDFKGQDYGYLPFG 233
            ETC++M YTIPK+S + VNVW +G D   W +DA++F+PERFLD++VDF+GQD+ ++PFG
Sbjct: 370  ETCKLMNYTIPKNSRLFVNVWAIGRDSKTW-EDALSFRPERFLDSSVDFRGQDFEFIPFG 428

Query: 232  AGRRMCPGFPFAAKQVHLIVAALVSSFEWSVAGNRNGGEFHHTQLDMKEAYSVPIRKEK 56
            AGRR CPG PFA ++VHLI+A+L+  FEWS+    +       QLDM+E + V ++KEK
Sbjct: 429  AGRRTCPGLPFARQEVHLILASLIHHFEWSIPNGED-----PMQLDMEEKFGVTLQKEK 482


>XP_002510830.1 PREDICTED: (S)-N-methylcoclaurine 3'-hydroxylase isozyme 1 [Ricinus
            communis] EEF51432.1 (S)-N-methylcoclaurine
            3'-hydroxylase isozyme, putative [Ricinus communis]
          Length = 496

 Score =  400 bits (1028), Expect = e-131
 Identities = 207/469 (44%), Positives = 310/469 (66%), Gaps = 6/469 (1%)
 Frame = -1

Query: 1447 LPPGPWPWPIVGNIPHVLMSVIINIPPPQTVANLSKIYGPLLSLKLGSRLVILASSPEAA 1268
            LPPGP PWPI+GNI  V   + I       +AN +K+YGPL+SL+LG++++++AS+P +A
Sbjct: 36   LPPGPKPWPILGNILQVDKKLHI------CIANFAKVYGPLISLRLGNQVLVVASTPSSA 89

Query: 1267 HAILNTHDRHLSGRYIAKATPIEAGELQRFSLLWSTERNSHSWKAIRDQWN-DLFSSKAM 1091
              +L  HDR LS R+I KA P E+  L+R +++W+   N H WK++R     +LFS KA+
Sbjct: 90   AEVLKNHDRLLSARFILKAIPSESHILERVAIVWNPACNDH-WKSLRALCRTELFSPKAI 148

Query: 1090 DDYVKMREAKVAEMLHFLKRERLGQMVNIRDVVFTMVYNTLGNICFSKNMVNLDDDGEKK 911
            +    +RE K+AEML FL  ++ GQ VN+ +VVF  ++NT+ ++ FS +++      E +
Sbjct: 149  ESQAILREKKLAEMLEFLITKQ-GQAVNVAEVVFGTIFNTISHLLFSTDLIGF----ENQ 203

Query: 910  SSEVKKTIWGLMESGTTPILADFFPVFEGFDVQGARRRTKGCIDRLYKVWEGIIQTRRRG 731
               VK  +W +ME  T+P +A+F+P+    D QG +R+   C+  ++ VWE  I+ RRR 
Sbjct: 204  IGGVKSLLWSMMEMATSPNIAEFYPILAPLDPQGLKRKMTKCLKEMFGVWEIYIKERRR- 262

Query: 730  ESTNNDGATKHGDFLHFMLANGWSDLQIKHMLLEVFPAATGNIPTTVEWAVAELIKNEEA 551
             + ++D A    DFL   L+NG+ D QI  +++E+  A T    T+VEWA+AEL+KN+EA
Sbjct: 263  -THDHDHAAPKTDFLDIFLSNGFDDDQINWLVMELLSAGTDTTSTSVEWAMAELLKNKEA 321

Query: 550  MKKVRQELSTVT----LSEGAILELPYLNACIKETLRLHPPIGFL-PHCAQETCQVMGYT 386
            MKKVR+EL        + E  + +LPYLNAC+KETLRLHPP  FL P  A E C+VM YT
Sbjct: 322  MKKVREELDREINKNPIKESHVSQLPYLNACVKETLRLHPPAPFLIPRRATENCEVMNYT 381

Query: 385  IPKDSLVIVNVWGMGHDKNIWGQDAVAFKPERFLDTNVDFKGQDYGYLPFGAGRRMCPGF 206
            IPKDS V+VNVW +G D ++W +D  +FKPERFL +++D KG D+  +PFG+GRR+CPG 
Sbjct: 382  IPKDSQVLVNVWAIGRDPSVW-EDPSSFKPERFLGSSLDVKGHDFELIPFGSGRRICPGL 440

Query: 205  PFAAKQVHLIVAALVSSFEWSVAGNRNGGEFHHTQLDMKEAYSVPIRKE 59
            P A +Q+ L++A+L+  F+WS+    NGG+    ++DM E + + ++ E
Sbjct: 441  PMATRQLSLVLASLIHCFDWSLP---NGGD--PAKVDMTEKFGITLQME 484


>XP_002274562.1 PREDICTED: probable (S)-N-methylcoclaurine 3'-hydroxylase isozyme 2
            [Vitis vinifera]
          Length = 498

 Score =  398 bits (1023), Expect = e-130
 Identities = 209/470 (44%), Positives = 301/470 (64%), Gaps = 6/470 (1%)
 Frame = -1

Query: 1447 LPPGPWPWPIVGNIPHVLMSVIINIPPPQTVANLSKIYGPLLSLKLGSRLVILASSPEAA 1268
            LPPGP+PWPI+GN+  +  +      P   +ANL+K++GPL+SL+LG++L+++ASSP AA
Sbjct: 38   LPPGPYPWPIIGNLLQMGKN------PHAKLANLAKLHGPLMSLRLGTQLMVVASSPAAA 91

Query: 1267 HAILNTHDRHLSGRYIAKATPIEAGELQRFSLLWSTERNSHSWKAIRDQWN-DLFSSKAM 1091
              +L THDR LSGRY++ + P++  +L   S++++ + N++ WK +R     +LFS KAM
Sbjct: 92   MEVLKTHDRALSGRYLSSSVPVKNPKLNHLSIVFAKDCNTN-WKNLRAICRMELFSGKAM 150

Query: 1090 DDYVKMREAKVAEMLHFLKRERLGQMVNIRDVVFTMVYNTLGNICFSKNMVNLDDDGEKK 911
            +  V++RE KV E++ FL  +  G++V + D+VFT + N L N  FS ++ + +D+G + 
Sbjct: 151  ESQVELRERKVTELVEFLATKE-GEVVKVMDLVFTTICNILSNKFFSMDLCDFEDEG-RV 208

Query: 910  SSEVKKTIWGLMESGTTPILADFFPVFEGFDVQGARRRTKGCIDRLYKVWEGIIQTRRRG 731
               +K  I    E G TP L+D++P+  G D+QG  R+ K   +R+   WE I++ RR  
Sbjct: 209  GGALKDLIHKNAEFGATPNLSDYYPILGGLDIQGINRKAKEMFERIPTTWEDILKERR-- 266

Query: 730  ESTNNDGATKHGDFLHFMLANGWSDLQIKHMLLEVFPAATGNIPTTVEWAVAELIKNEEA 551
              T     + H DFL  +L  G+ D QI  ++LE+F A       TVEWA+AELI+N++A
Sbjct: 267  --TQRSNRSSHRDFLEALLEIGFEDDQINQVILELFSAGAETSSLTVEWAMAELIRNQDA 324

Query: 550  MKKVRQELSTVT----LSEGAILELPYLNACIKETLRLHPPIGFL-PHCAQETCQVMGYT 386
            M K+R EL  +     + E  +  LPYL AC+KE LRLHPP   L PH A ETCQVMGYT
Sbjct: 325  MDKLRGELRQIVGESPVRESHLPRLPYLQACVKEALRLHPPAPLLLPHLAAETCQVMGYT 384

Query: 385  IPKDSLVIVNVWGMGHDKNIWGQDAVAFKPERFLDTNVDFKGQDYGYLPFGAGRRMCPGF 206
            IPKDS + VN+W M  D  IW  D ++FKPERFLD+ +DFKG D+ Y+PFGAGRR+CPG 
Sbjct: 385  IPKDSQIFVNIWAMARDPKIW-DDPLSFKPERFLDSKLDFKGNDFEYIPFGAGRRICPGL 443

Query: 205  PFAAKQVHLIVAALVSSFEWSVAGNRNGGEFHHTQLDMKEAYSVPIRKEK 56
                +QV LI+A  V  F WS+ GN +       QLDM+E   + +RKE+
Sbjct: 444  ALGGRQVPLILATFVHLFGWSLPGNMDS-----AQLDMEEWLVITLRKEQ 488


>CAN62647.1 hypothetical protein VITISV_013219 [Vitis vinifera]
          Length = 498

 Score =  398 bits (1022), Expect = e-130
 Identities = 209/470 (44%), Positives = 301/470 (64%), Gaps = 6/470 (1%)
 Frame = -1

Query: 1447 LPPGPWPWPIVGNIPHVLMSVIINIPPPQTVANLSKIYGPLLSLKLGSRLVILASSPEAA 1268
            LPPGP+PWPI+GN+  +  +      P   +ANL+K++GPL+SL+LG++L+++ASSP AA
Sbjct: 38   LPPGPYPWPIIGNLLQMGKN------PHAKLANLAKLHGPLMSLRLGTQLMVVASSPAAA 91

Query: 1267 HAILNTHDRHLSGRYIAKATPIEAGELQRFSLLWSTERNSHSWKAIRDQWN-DLFSSKAM 1091
              +L THDR LSGRY++ + P++  +L   S++++ + N++ WK +R     +LFS KAM
Sbjct: 92   MEVLKTHDRALSGRYLSXSVPVKNPKLNHLSIVFAKDCNTN-WKNLRAICRMELFSGKAM 150

Query: 1090 DDYVKMREAKVAEMLHFLKRERLGQMVNIRDVVFTMVYNTLGNICFSKNMVNLDDDGEKK 911
            +  V++RE KV E++ FL  +  G++V + D+VFT + N L N  FS ++ + +D+G + 
Sbjct: 151  ESQVELRERKVTELVEFLATKE-GEVVKVMDLVFTTICNILSNKFFSMDLCDFEDEG-RV 208

Query: 910  SSEVKKTIWGLMESGTTPILADFFPVFEGFDVQGARRRTKGCIDRLYKVWEGIIQTRRRG 731
               +K  I    E G TP L+D++P+  G D+QG  R+ K   +R+   WE I++ RR  
Sbjct: 209  GGALKDLIHKNAEFGATPNLSDYYPILGGLDIQGINRKAKEMFERIPTTWEDILKERR-- 266

Query: 730  ESTNNDGATKHGDFLHFMLANGWSDLQIKHMLLEVFPAATGNIPTTVEWAVAELIKNEEA 551
              T     + H DFL  +L  G+ D QI  ++LE+F A       TVEWA+AELI+N++A
Sbjct: 267  --TQRSNRSSHRDFLEALLEIGFEDDQINQVILELFSAGAETSSLTVEWAMAELIRNQDA 324

Query: 550  MKKVRQELSTVT----LSEGAILELPYLNACIKETLRLHPPIGFL-PHCAQETCQVMGYT 386
            M K+R EL  +     + E  +  LPYL AC+KE LRLHPP   L PH A ETCQVMGYT
Sbjct: 325  MDKLRGELRQIVGESPVRESHLPRLPYLQACVKEALRLHPPAPLLLPHLAAETCQVMGYT 384

Query: 385  IPKDSLVIVNVWGMGHDKNIWGQDAVAFKPERFLDTNVDFKGQDYGYLPFGAGRRMCPGF 206
            IPKDS + VN+W M  D  IW  D ++FKPERFLD+ +DFKG D+ Y+PFGAGRR+CPG 
Sbjct: 385  IPKDSQIFVNIWAMARDPKIW-DDPLSFKPERFLDSKLDFKGNDFEYIPFGAGRRICPGL 443

Query: 205  PFAAKQVHLIVAALVSSFEWSVAGNRNGGEFHHTQLDMKEAYSVPIRKEK 56
                +QV LI+A  V  F WS+ GN +       QLDM+E   + +RKE+
Sbjct: 444  ALGGRQVPLILATFVHLFGWSLPGNMDS-----AQLDMEEWLVITLRKEQ 488


>XP_009610421.1 PREDICTED: (S)-N-methylcoclaurine 3'-hydroxylase isozyme 1-like
            [Nicotiana tomentosiformis]
          Length = 489

 Score =  396 bits (1018), Expect = e-129
 Identities = 205/479 (42%), Positives = 315/479 (65%), Gaps = 7/479 (1%)
 Frame = -1

Query: 1471 VPSRGGENLPPGPWPWPIVGNIPHVLMSVIINIPPPQTVANLSKIYGPLLSLKLGSRLVI 1292
            +P  G  NLPPGP PWPI+GNI      + +   P  ++   +KI+GPL+ L+LG++LV+
Sbjct: 24   IPKSG--NLPPGPRPWPILGNI------LQLGKNPHISMTQFAKIHGPLICLRLGTQLVV 75

Query: 1291 LASSPEAAHAILNTHDRHLSGRYIAKATPIEAGELQRFSLLWSTERNSHSWKAIRDQWND 1112
            +ASSP++A  IL T DR LS R + +  P +   + + S++WS++  +H WK++R     
Sbjct: 76   IASSPDSAAEILKTQDRLLSARSVPRVAPYKLSVIDQHSIVWSSDLTNH-WKSLRAFCRT 134

Query: 1111 -LFSSKAMDDYVKMREAKVAEMLHFLKRERLGQMVNIRDVVFTMVYNTLGNICFSKNMVN 935
             LFS+KA++    +RE KV EM+ FL+  + G+ V I +++F  + NTLGN+ F+KN+ +
Sbjct: 135  HLFSAKAVESQADLREKKVFEMIEFLRSNK-GKTVKISEILFATILNTLGNLFFTKNLCD 193

Query: 934  LDDDGEKKSSEVKKTIWGLMESGTTPILADFFPVFEGFDVQGARRRTKGCIDRLYKVWEG 755
            LD +G   +S +K  I   +E G  P +++F+P  +  D+QG R+ T    D+L  +W  
Sbjct: 194  LDSEGN--TSGIKHVIRRFVELGAMPNISEFYPFLDALDLQGLRKLTNIYQDQLISIWAE 251

Query: 754  IIQTRRRGESTNNDGATKHGDFLHFMLANGWSDLQIKHMLLEVFPAATGNIPTTVEWAVA 575
            +++ +R+  S  +  + K+ DFL  M+ +G+SDLQI  +L+E+  A T    +T+EWA+A
Sbjct: 252  VVKEKRQAISCGS--SNKNQDFLDIMIDSGFSDLQINIILMELIAAGTDTTTSTIEWAMA 309

Query: 574  ELIKNEEAMKKVRQEL-----STVTLSEGAILELPYLNACIKETLRLHPPIGFL-PHCAQ 413
            EL++N++ M K++ E+     S   + E  I ELPYL AC+KETLR+HPP  FL P  A 
Sbjct: 310  ELLRNKKVMHKLQAEIRSKIGSNANIRESNISELPYLAACVKETLRIHPPTPFLVPRRAP 369

Query: 412  ETCQVMGYTIPKDSLVIVNVWGMGHDKNIWGQDAVAFKPERFLDTNVDFKGQDYGYLPFG 233
            ETC++M +TIPK+S + VNVW +G D   W +DA++F+PERFLD++VDF+GQD+ ++PFG
Sbjct: 370  ETCKLMNFTIPKNSRLFVNVWAIGRDSKTW-EDALSFRPERFLDSSVDFRGQDFEFIPFG 428

Query: 232  AGRRMCPGFPFAAKQVHLIVAALVSSFEWSVAGNRNGGEFHHTQLDMKEAYSVPIRKEK 56
            AGRR+CPG PFA ++VHLI+A+L+  FEWSV    +       QLDM E + V ++KEK
Sbjct: 429  AGRRICPGLPFARQEVHLILASLIHHFEWSVPNGED-----PMQLDMGEKFGVTLQKEK 482


>XP_009757123.1 PREDICTED: probable (S)-N-methylcoclaurine 3'-hydroxylase isozyme 2
            isoform X1 [Nicotiana sylvestris] XP_009757124.1
            PREDICTED: probable (S)-N-methylcoclaurine 3'-hydroxylase
            isozyme 2 isoform X2 [Nicotiana sylvestris]
          Length = 489

 Score =  394 bits (1012), Expect = e-128
 Identities = 207/479 (43%), Positives = 318/479 (66%), Gaps = 7/479 (1%)
 Frame = -1

Query: 1471 VPSRGGENLPPGPWPWPIVGNIPHVLMSVIINIPPPQTVANLSKIYGPLLSLKLGSRLVI 1292
            +P  G  NLPPGP PWPI+GNI      + +   P  ++   +KI+GPL+SL+LG++LV+
Sbjct: 24   IPKSG--NLPPGPRPWPILGNI------LQLGKNPHISMTQFAKIHGPLISLRLGTQLVV 75

Query: 1291 LASSPEAAHAILNTHDRHLSGRYIAKATPIEAGELQRFSLLWSTERNSHSWKAIRDQWND 1112
            +ASSP++A  IL T DR LS R + +  P +   + + SL+WS++ ++H WK++R     
Sbjct: 76   IASSPDSAAEILKTQDRLLSARSVPRVAPYKLSVVDQHSLVWSSDLSNH-WKSLRAFCRT 134

Query: 1111 -LFSSKAMDDYVKMREAKVAEMLHFLKRERLGQMVNIRDVVFTMVYNTLGNICFSKNMVN 935
             LFS+KA++    +RE KV EM+ FL R + G+ V I +++F  + NTLGN+ F+K++ +
Sbjct: 135  HLFSAKAVESQAALREKKVFEMIEFL-RSKKGKTVKISEIMFATILNTLGNLFFTKDLCD 193

Query: 934  LDDDGEKKSSEVKKTIWGLMESGTTPILADFFPVFEGFDVQGARRRTKGCIDRLYKVWEG 755
            LD +G   +S +K  I   +E G  P +++F+P  +  D+QG R++TK    +L+ +W  
Sbjct: 194  LDYEGN--TSGIKHVIRKFVELGAMPNISEFYPFLDALDLQGLRKQTKIYQGQLFNIWAE 251

Query: 754  IIQTRRRGESTNNDGATKHGDFLHFMLANGWSDLQIKHMLLEVFPAATGNIPTTVEWAVA 575
            I++ +R+  S  +  + K  DFL  M+ +G++DLQI  +L+E+  A T    +T+EWA+A
Sbjct: 252  IVKEKRQAISRGS--SNKIQDFLDIMIYSGFTDLQINIILMELIAAGTDTTTSTIEWAMA 309

Query: 574  ELIKNEEAMKKVRQEL-----STVTLSEGAILELPYLNACIKETLRLHPPIGFL-PHCAQ 413
            EL++N+E M K++ EL     S   + E  I ELPYL AC+KETLR+HPP  FL P  A 
Sbjct: 310  ELLRNKEVMHKLQAELRSKIGSNAIIRESNISELPYLAACVKETLRIHPPTPFLIPRRAP 369

Query: 412  ETCQVMGYTIPKDSLVIVNVWGMGHDKNIWGQDAVAFKPERFLDTNVDFKGQDYGYLPFG 233
            ETC++M YTIPK+S + VNVW +G D   W +DA++F+PERF+D++VDF+GQD+ ++PFG
Sbjct: 370  ETCKLMNYTIPKNSRLFVNVWAIGCDSKTW-EDALSFRPERFIDSSVDFRGQDFEFIPFG 428

Query: 232  AGRRMCPGFPFAAKQVHLIVAALVSSFEWSVAGNRNGGEFHHTQLDMKEAYSVPIRKEK 56
            AGRR+CPG PFA ++VHLI+A+L+  FEWS+    +        LDM+E + V ++KEK
Sbjct: 429  AGRRICPGLPFARQEVHLILASLIHHFEWSLPYGED-----PMLLDMEEKFGVTLQKEK 482


>XP_016461059.1 PREDICTED: probable (S)-N-methylcoclaurine 3'-hydroxylase isozyme 2
            [Nicotiana tabacum]
          Length = 489

 Score =  394 bits (1011), Expect = e-128
 Identities = 207/479 (43%), Positives = 317/479 (66%), Gaps = 7/479 (1%)
 Frame = -1

Query: 1471 VPSRGGENLPPGPWPWPIVGNIPHVLMSVIINIPPPQTVANLSKIYGPLLSLKLGSRLVI 1292
            +P  G  NLPPGP PWPI+GNI      + +   P  ++   +KI+GPL+SL+LG++LV+
Sbjct: 24   IPKSG--NLPPGPRPWPILGNI------LQLGKNPHISMTQFAKIHGPLISLRLGTQLVV 75

Query: 1291 LASSPEAAHAILNTHDRHLSGRYIAKATPIEAGELQRFSLLWSTERNSHSWKAIRDQWND 1112
            +ASSP++A  IL T DR LS R + +  P +   + + SL+WS++ ++H WK++R     
Sbjct: 76   IASSPDSAAEILKTQDRLLSARSVPRVAPYKLSVVDQHSLVWSSDLSNH-WKSLRAFCRT 134

Query: 1111 -LFSSKAMDDYVKMREAKVAEMLHFLKRERLGQMVNIRDVVFTMVYNTLGNICFSKNMVN 935
             LFS+KA++    +RE KV EM+ FL R + G+ V I +++F  + NTLGN+ F+K++ +
Sbjct: 135  HLFSAKAVESQAALREKKVFEMIEFL-RSKKGKTVKISEIMFATILNTLGNLFFTKDLCD 193

Query: 934  LDDDGEKKSSEVKKTIWGLMESGTTPILADFFPVFEGFDVQGARRRTKGCIDRLYKVWEG 755
            LD +G   +S +K  I   +E G  P +++F+P  +  D+QG R++TK    +L+ +W  
Sbjct: 194  LDYEGN--TSGIKHVIRKFVELGAMPNISEFYPFLDALDLQGLRKQTKIYQGQLFNIWAE 251

Query: 754  IIQTRRRGESTNNDGATKHGDFLHFMLANGWSDLQIKHMLLEVFPAATGNIPTTVEWAVA 575
            I++ +R+  S  +  + K  DFL  M+ +G++DLQI  +L+E+  A T    +T+EWA A
Sbjct: 252  IVKEKRQAISRGS--SNKIQDFLDIMIYSGFTDLQINIILMELIAAGTDTTTSTIEWATA 309

Query: 574  ELIKNEEAMKKVRQEL-----STVTLSEGAILELPYLNACIKETLRLHPPIGFL-PHCAQ 413
            EL++N+E M K++ EL     S   + E  I ELPYL AC+KETLR+HPP  FL P  A 
Sbjct: 310  ELLRNKEVMHKLQAELRSKIGSNAIIRESNISELPYLAACVKETLRIHPPTPFLIPRRAP 369

Query: 412  ETCQVMGYTIPKDSLVIVNVWGMGHDKNIWGQDAVAFKPERFLDTNVDFKGQDYGYLPFG 233
            ETC++M YTIPK+S + VNVW +G D   W +DA++F+PERF+D++VDF+GQD+ ++PFG
Sbjct: 370  ETCKLMNYTIPKNSRLFVNVWAIGCDSKTW-EDALSFRPERFIDSSVDFRGQDFEFIPFG 428

Query: 232  AGRRMCPGFPFAAKQVHLIVAALVSSFEWSVAGNRNGGEFHHTQLDMKEAYSVPIRKEK 56
            AGRR+CPG PFA ++VHLI+A+L+  FEWS+    +        LDM+E + V ++KEK
Sbjct: 429  AGRRICPGLPFARQEVHLILASLIHHFEWSLPYGED-----PMLLDMEEKFGVTLQKEK 482


>XP_002318833.1 hypothetical protein POPTR_0012s13580g [Populus trichocarpa]
            EEE97053.1 hypothetical protein POPTR_0012s13580g
            [Populus trichocarpa]
          Length = 503

 Score =  394 bits (1012), Expect = e-128
 Identities = 215/470 (45%), Positives = 309/470 (65%), Gaps = 6/470 (1%)
 Frame = -1

Query: 1447 LPPGPWPWPIVGNIPHVLMSVIINIPPPQTVANLSKIYGPLLSLKLGSRLVILASSPEAA 1268
            LPPGP PWPI+GN+ HV         P  ++A ++KI+GPL+SL+LG++L+++ SS +AA
Sbjct: 44   LPPGPKPWPIIGNLLHV------GNQPHVSLAEIAKIHGPLISLRLGTQLLVVGSSAKAA 97

Query: 1267 HAILNTHDRHLSGRYIAKATPIEAGELQRFSLLWSTERNSHSWKAIRDQWN-DLFSSKAM 1091
              IL THDR LS R++ +  P E+  L+R +L+W  E +  +WK +R     +LFS+KA+
Sbjct: 98   AEILKTHDRFLSARHVPQVIPRESHVLRRVALVWCPE-SIDTWKLLRGLCRTELFSAKAI 156

Query: 1090 DDYVKMREAKVAEMLHFLKRERLGQMVNIRDVVFTMVYNTLGNICFSKNMVNLDDDGEKK 911
            +    +RE KV E++ FL   R G++V+I +VVF+ V+NT+ N+ FS ++  L++ G   
Sbjct: 157  ESSATLREKKVGELMDFLVA-REGKVVSIGEVVFSTVFNTISNLLFSNDLAGLEEKG--M 213

Query: 910  SSEVKKTIWGLMESGTTPILADFFPVFEGFDVQGARRRTKGCIDRLYKVWEGIIQTRRRG 731
            SS +K  +  LM    TP +ADF+P+F G D QG RR+    ++  + +W   I  + R 
Sbjct: 214  SSGLKSHVRKLMLLVATPNIADFYPIFAGLDPQGLRRKLSKLVEETFAIWA--INIKERR 271

Query: 730  ESTNNDGATKHGDFLHFMLANGWSDLQIKHMLLEVFPAATGNIPTTVEWAVAELIKNEEA 551
             S  +D   +  DFL   LANG+ D QI  +  E+F A T    TT+EWAVAE++KN+E 
Sbjct: 272  NSYVHDSPKR--DFLDVFLANGFDDDQINWLAAELFSAGTDTTATTIEWAVAEILKNKEV 329

Query: 550  MKKVRQELSTV----TLSEGAILELPYLNACIKETLRLHPPIGFL-PHCAQETCQVMGYT 386
            MKKV +EL       T+SE  +  LPYLNACIKETLRLHPP+  L PH A ETC+VM YT
Sbjct: 330  MKKVDEELEREITKNTISESDVSGLPYLNACIKETLRLHPPVPLLVPHRATETCEVMKYT 389

Query: 385  IPKDSLVIVNVWGMGHDKNIWGQDAVAFKPERFLDTNVDFKGQDYGYLPFGAGRRMCPGF 206
            IPKDS V+VNVW +  D + W +D ++FKP+RFL +N++FKG +Y +LPFGAGRR+CPG 
Sbjct: 390  IPKDSQVLVNVWAISRDPSTW-EDPLSFKPDRFLGSNLEFKGGNYEFLPFGAGRRICPGL 448

Query: 205  PFAAKQVHLIVAALVSSFEWSVAGNRNGGEFHHTQLDMKEAYSVPIRKEK 56
            P A K V LI+A+L+  F+WS+    NG +    +LDMK+ + V ++KE+
Sbjct: 449  PMANKLVPLILASLIRCFDWSLP---NGEDL--AKLDMKDKFGVVLQKEQ 493


>XP_016564639.1 PREDICTED: probable (S)-N-methylcoclaurine 3'-hydroxylase isozyme 2
            [Capsicum annuum]
          Length = 494

 Score =  394 bits (1011), Expect = e-128
 Identities = 203/472 (43%), Positives = 318/472 (67%), Gaps = 7/472 (1%)
 Frame = -1

Query: 1450 NLPPGPWPWPIVGNIPHVLMSVIINIPPPQTVANLSKIYGPLLSLKLGSRLVILASSPEA 1271
            NLPPGP PWP++GNI      ++I   P  ++A  +KI+G L+S++LGS+LV++ASSP+ 
Sbjct: 34   NLPPGPRPWPVLGNI------LLIGKKPHISLAQFAKIHGSLISVRLGSQLVVVASSPDT 87

Query: 1270 AHAILNTHDRHLSGRYIAKATPIEAGELQRFSLLWSTERNSHSWKAIRDQWND-LFSSKA 1094
            A  IL T DR LS R + K    +   + + S++WS++ ++H WK +R      LFS KA
Sbjct: 88   AAEILKTQDRLLSARSVPKVATYDLSVIDQHSIVWSSDLSNH-WKILRAFCRTHLFSPKA 146

Query: 1093 MDDYVKMREAKVAEMLHFLKRERLGQMVNIRDVVFTMVYNTLGNICFSKNMVNLDDDGEK 914
            ++    +RE KV+EM+ FL+  + G+ V I +++F  + N LGN+ FSK++  LD +G  
Sbjct: 147  IESQAALREKKVSEMIDFLRSNK-GETVKISEILFGTILNMLGNLFFSKDLCQLDYEGN- 204

Query: 913  KSSEVKKTIWGLMESGTTPILADFFPVFEGFDVQGARRRTKGCIDRLYKVWEGIIQTRRR 734
             +S +K  I   +E G  P +++F+P+F+  D+QG R++T+   ++L  +W  I++ +R+
Sbjct: 205  -TSGIKHVIRKFVELGAMPNISEFYPIFDALDIQGLRKQTEIYQNQLIDIWNEIVKEKRQ 263

Query: 733  GESTNNDGATKHGDFLHFMLANGWSDLQIKHMLLEVFPAATGNIPTTVEWAVAELIKNEE 554
              S  +  +TK+ DFL  M+ +G+SDLQI  +L+E+  A +    +T+EWA+AEL++N++
Sbjct: 264  AISLGS--STKNLDFLDVMIHSGFSDLQINILLMELIAAGSDTTTSTIEWAMAELLRNKD 321

Query: 553  AMKKVRQELSTVT-----LSEGAILELPYLNACIKETLRLHPPIGFL-PHCAQETCQVMG 392
            +M K++ EL +       ++E  I ELPYL AC+KETLR+HPP  FL P  A ET ++M 
Sbjct: 322  SMHKLQAELRSKMGENDIITESNISELPYLAACVKETLRIHPPTPFLIPRRAPETFKIMD 381

Query: 391  YTIPKDSLVIVNVWGMGHDKNIWGQDAVAFKPERFLDTNVDFKGQDYGYLPFGAGRRMCP 212
            YTIPK+S + VNVW +G D N W +D ++F+PERFLD+N+DF+GQD+ ++PFGAGRR+CP
Sbjct: 382  YTIPKNSRLFVNVWAIGRDSNTW-EDPLSFRPERFLDSNLDFRGQDFEFIPFGAGRRICP 440

Query: 211  GFPFAAKQVHLIVAALVSSFEWSVAGNRNGGEFHHTQLDMKEAYSVPIRKEK 56
            G PFA ++VHLI+A+L+  FEWS+  + +       QLDM+E + V ++KEK
Sbjct: 441  GLPFARQEVHLILASLIHYFEWSLPNDED-----PMQLDMEEKFGVTLQKEK 487