BLASTX 2.2.26 [Sep-21-2011]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= Lithospermum23_contig00001606
         (2419 letters)

Database: ./nr 
           115,041,592 sequences; 42,171,959,267 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

XP_012830709.1 PREDICTED: DNA topoisomerase 2-binding protein 1-...   364   e-154
XP_012830710.1 PREDICTED: DNA topoisomerase 2-binding protein 1-...   364   e-153
EYU42965.1 hypothetical protein MIMGU_mgv1a001282mg [Erythranthe...   349   e-148
CDP16447.1 unnamed protein product [Coffea canephora]                 421   e-130
XP_016440871.1 PREDICTED: uncharacterized protein LOC107766582 [...   396   e-126
XP_015063139.1 PREDICTED: DNA topoisomerase 2-binding protein 1 ...   400   e-123
XP_010320796.1 PREDICTED: DNA topoisomerase 2-binding protein 1 ...   399   e-122
EEF42097.1 topbp1, putative [Ricinus communis]                        400   e-122
XP_015063138.1 PREDICTED: DNA topoisomerase 2-binding protein 1 ...   400   e-122
XP_010320793.1 PREDICTED: DNA topoisomerase 2-binding protein 1 ...   399   e-121
XP_019167495.1 PREDICTED: DNA topoisomerase 2-binding protein 1-...   398   e-121
XP_009788829.1 PREDICTED: DNA topoisomerase 2-binding protein 1 ...   397   e-121
XP_009788828.1 PREDICTED: DNA topoisomerase 2-binding protein 1 ...   397   e-121
XP_009788827.1 PREDICTED: DNA topoisomerase 2-binding protein 1 ...   397   e-121
XP_015575415.1 PREDICTED: DNA topoisomerase 2-binding protein 1-...   394   e-120
XP_010664171.1 PREDICTED: DNA topoisomerase 2-binding protein 1-...   394   e-120
CBI18968.3 unnamed protein product, partial [Vitis vinifera]          394   e-120
XP_010664170.1 PREDICTED: DNA topoisomerase 2-binding protein 1-...   394   e-119
XP_019246538.1 PREDICTED: DNA topoisomerase 2-binding protein 1 ...   390   e-118
XP_016472763.1 PREDICTED: DNA topoisomerase 2-binding protein 1 ...   390   e-118

>XP_012830709.1 PREDICTED: DNA topoisomerase 2-binding protein 1-A isoform X1
            [Erythranthe guttata]
          Length = 842

 Score =  364 bits (934), Expect(2) = e-154
 Identities = 216/489 (44%), Positives = 282/489 (57%), Gaps = 13/489 (2%)
 Frame = +2

Query: 743  VREGKPSAVSFSAEPEIFVNKEIPIRATSNYIEQPTMSSLNGKGPLKVQPSSGIEIDERK 922
            V++GKP A S   +  I  NK+          E+           +K+Q      I   K
Sbjct: 387  VKQGKP-ATSQPVDDNILENKKSQYEGLFGLKEE-----------IKLQSGVSNGIKHVK 434

Query: 923  SSNVFKGRLFRFSPSFPAARRGEIIQWINEGGGQIFGDCIDIDSDFTVECHGV--VPSDA 1096
            S  VFKG+LFRFS SFP  ++ EI+ W+N GGG +  D  + +  F VE HGV  +    
Sbjct: 435  SPTVFKGKLFRFSSSFPEEQKPEIVLWVNGGGG-VVADRNETNVHFIVERHGVPCLTKTI 493

Query: 1097 GSVYVSSHWVKSSLEDGRLLDVGSHILYSPLPCQIPFVSLEKFKICISQYNEKERSLLKN 1276
             S YV+ HW+ S LEDG LLDV SHILYSPL C+IP    E +++C+S+Y+ KE+ LL+N
Sbjct: 494  RSTYVTPHWIHSCLEDGCLLDVSSHILYSPLSCEIPLPGFEGYRVCVSRYDTKEKQLLRN 553

Query: 1277 LCFVLGTKFTEKLTKSVTHLLCKFASGPKYEASCKWGMQSVTAEWLYECIKQNKVIDPDP 1456
            LC+VLG KFTEKL K VTHLLCKFA G KYEA+ +WG+  VTAEW+YEC  QNKV+D   
Sbjct: 554  LCYVLGGKFTEKLNKKVTHLLCKFADGDKYEAASRWGVHIVTAEWIYECAMQNKVVDLKR 613

Query: 1457 FHPKQATSQEREAGLCTMSQYPTQAFQMTSGDNASQLPIQSEELKNVQNESHPRKVVGFE 1636
            F+PK+ TSQER++GL ++SQYPT++F M SG++ SQ P Q + LKN+Q +   R +    
Sbjct: 614  FYPKELTSQERQSGLNSLSQYPTESFSMPSGNDVSQYPDQWQHLKNMQTDPSTRCMARDN 673

Query: 1637 ETVPPSSCRKREASIAENPTSMLSSVSKQFDHGLTVLSTKNMEESAKVVSEFH------- 1795
            +  P  S +K  A ++EN     SS++ Q     T   + N+++S   +   +       
Sbjct: 674  KEFPNGSIKK--ARLSEN-----SSINHQLSDDATTPCSVNVKDSTDAIVNGNTTEATPV 726

Query: 1796 --DDVAAIEDLLEQTSTISDHMSTEISLFPFDGSLRGQASDCTIRDQATDFSIRGLDDVD 1969
              D  AAIED LEQTS I +  S E              SDC      ++ S+ G    D
Sbjct: 727  VPDVAAAIEDFLEQTSKIQEWKSQE-------------KSDCHENFMPSNSSMLGQRHAD 773

Query: 1970 PSSYTKVQMDCINRPARNFDKINLPRTVATEAYDNFSETQTDSQIVGYAEDLSGRQMIID 2149
            P S+       +NR  R  D        A   YDNFSETQTDSQ+VGY EDLSGRQMIID
Sbjct: 774  PQSFPGPSKQWMNRVDRKDDSPPADAAAAKGLYDNFSETQTDSQVVGYEEDLSGRQMIID 833

Query: 2150 RV--RSSMT 2170
            RV  RSSMT
Sbjct: 834  RVRTRSSMT 842



 Score =  213 bits (543), Expect(2) = e-154
 Identities = 119/240 (49%), Positives = 155/240 (64%), Gaps = 4/240 (1%)
 Frame = +1

Query: 4   PEGDKYVVAKQWGHILIVTRKWFDQSLSRRVCLNEESYPVQSTPASSLSISRKKARHSQE 183
           PEGDKY VAK+WG I IV++KWF QS++RR CLNEESYPVQS  ASS  +S  K      
Sbjct: 133 PEGDKYKVAKRWGCIHIVSKKWFHQSIARRACLNEESYPVQSNLASS--VSSLKTVEKNI 190

Query: 184 TSSGISQCAKPSAGMASSSE----LCGPTISQDPEVTVSHNIFTVVSEVSMFNNDGEXXX 351
              GI      S+ MAS+S+       P +  D E+ +  N+     EV     +G    
Sbjct: 191 NGKGIRSSHFTSSYMASASDSETNFSAPDMEYDLEIPLP-NVHPTCLEVPPLPAEGSEPP 249

Query: 352 XXXXXXXXXXNASEPNVDIPLNNCIANDSQTEDNDLYLSECRITIVGFEASELRKLVSIV 531
                      A +   D    +CIA+DSQ+E+++LYLSECRI +VGFE SELRK+V +V
Sbjct: 250 -----------AEKLKNDSDFAHCIADDSQSENDNLYLSECRIMLVGFETSELRKVVDMV 298

Query: 532 RRGGGSRYMHFNEKLTHIVVGSPSEIEIRETRTLASRGIIHVVKKEWLEDCDREKKEFPV 711
           R+GGGSRYM F+EKLTH+VVG+PS+IEI+E R LAS G+I++VK  WL++C R+KKE PV
Sbjct: 299 RQGGGSRYMSFSEKLTHVVVGNPSDIEIKEARNLASFGVIYIVKTAWLDECTRKKKEVPV 358


>XP_012830710.1 PREDICTED: DNA topoisomerase 2-binding protein 1-B isoform X2
            [Erythranthe guttata]
          Length = 725

 Score =  364 bits (934), Expect(2) = e-153
 Identities = 216/489 (44%), Positives = 282/489 (57%), Gaps = 13/489 (2%)
 Frame = +2

Query: 743  VREGKPSAVSFSAEPEIFVNKEIPIRATSNYIEQPTMSSLNGKGPLKVQPSSGIEIDERK 922
            V++GKP A S   +  I  NK+          E+           +K+Q      I   K
Sbjct: 270  VKQGKP-ATSQPVDDNILENKKSQYEGLFGLKEE-----------IKLQSGVSNGIKHVK 317

Query: 923  SSNVFKGRLFRFSPSFPAARRGEIIQWINEGGGQIFGDCIDIDSDFTVECHGV--VPSDA 1096
            S  VFKG+LFRFS SFP  ++ EI+ W+N GGG +  D  + +  F VE HGV  +    
Sbjct: 318  SPTVFKGKLFRFSSSFPEEQKPEIVLWVNGGGG-VVADRNETNVHFIVERHGVPCLTKTI 376

Query: 1097 GSVYVSSHWVKSSLEDGRLLDVGSHILYSPLPCQIPFVSLEKFKICISQYNEKERSLLKN 1276
             S YV+ HW+ S LEDG LLDV SHILYSPL C+IP    E +++C+S+Y+ KE+ LL+N
Sbjct: 377  RSTYVTPHWIHSCLEDGCLLDVSSHILYSPLSCEIPLPGFEGYRVCVSRYDTKEKQLLRN 436

Query: 1277 LCFVLGTKFTEKLTKSVTHLLCKFASGPKYEASCKWGMQSVTAEWLYECIKQNKVIDPDP 1456
            LC+VLG KFTEKL K VTHLLCKFA G KYEA+ +WG+  VTAEW+YEC  QNKV+D   
Sbjct: 437  LCYVLGGKFTEKLNKKVTHLLCKFADGDKYEAASRWGVHIVTAEWIYECAMQNKVVDLKR 496

Query: 1457 FHPKQATSQEREAGLCTMSQYPTQAFQMTSGDNASQLPIQSEELKNVQNESHPRKVVGFE 1636
            F+PK+ TSQER++GL ++SQYPT++F M SG++ SQ P Q + LKN+Q +   R +    
Sbjct: 497  FYPKELTSQERQSGLNSLSQYPTESFSMPSGNDVSQYPDQWQHLKNMQTDPSTRCMARDN 556

Query: 1637 ETVPPSSCRKREASIAENPTSMLSSVSKQFDHGLTVLSTKNMEESAKVVSEFH------- 1795
            +  P  S +K  A ++EN     SS++ Q     T   + N+++S   +   +       
Sbjct: 557  KEFPNGSIKK--ARLSEN-----SSINHQLSDDATTPCSVNVKDSTDAIVNGNTTEATPV 609

Query: 1796 --DDVAAIEDLLEQTSTISDHMSTEISLFPFDGSLRGQASDCTIRDQATDFSIRGLDDVD 1969
              D  AAIED LEQTS I +  S E              SDC      ++ S+ G    D
Sbjct: 610  VPDVAAAIEDFLEQTSKIQEWKSQE-------------KSDCHENFMPSNSSMLGQRHAD 656

Query: 1970 PSSYTKVQMDCINRPARNFDKINLPRTVATEAYDNFSETQTDSQIVGYAEDLSGRQMIID 2149
            P S+       +NR  R  D        A   YDNFSETQTDSQ+VGY EDLSGRQMIID
Sbjct: 657  PQSFPGPSKQWMNRVDRKDDSPPADAAAAKGLYDNFSETQTDSQVVGYEEDLSGRQMIID 716

Query: 2150 RV--RSSMT 2170
            RV  RSSMT
Sbjct: 717  RVRTRSSMT 725



 Score =  209 bits (531), Expect(2) = e-153
 Identities = 117/238 (49%), Positives = 153/238 (64%), Gaps = 4/238 (1%)
 Frame = +1

Query: 10  GDKYVVAKQWGHILIVTRKWFDQSLSRRVCLNEESYPVQSTPASSLSISRKKARHSQETS 189
           GDKY VAK+WG I IV++KWF QS++RR CLNEESYPVQS  ASS  +S  K        
Sbjct: 18  GDKYKVAKRWGCIHIVSKKWFHQSIARRACLNEESYPVQSNLASS--VSSLKTVEKNING 75

Query: 190 SGISQCAKPSAGMASSSE----LCGPTISQDPEVTVSHNIFTVVSEVSMFNNDGEXXXXX 357
            GI      S+ MAS+S+       P +  D E+ +  N+     EV     +G      
Sbjct: 76  KGIRSSHFTSSYMASASDSETNFSAPDMEYDLEIPLP-NVHPTCLEVPPLPAEGSEPP-- 132

Query: 358 XXXXXXXXNASEPNVDIPLNNCIANDSQTEDNDLYLSECRITIVGFEASELRKLVSIVRR 537
                    A +   D    +CIA+DSQ+E+++LYLSECRI +VGFE SELRK+V +VR+
Sbjct: 133 ---------AEKLKNDSDFAHCIADDSQSENDNLYLSECRIMLVGFETSELRKVVDMVRQ 183

Query: 538 GGGSRYMHFNEKLTHIVVGSPSEIEIRETRTLASRGIIHVVKKEWLEDCDREKKEFPV 711
           GGGSRYM F+EKLTH+VVG+PS+IEI+E R LAS G+I++VK  WL++C R+KKE PV
Sbjct: 184 GGGSRYMSFSEKLTHVVVGNPSDIEIKEARNLASFGVIYIVKTAWLDECTRKKKEVPV 241


>EYU42965.1 hypothetical protein MIMGU_mgv1a001282mg [Erythranthe guttata]
          Length = 847

 Score =  349 bits (895), Expect(2) = e-148
 Identities = 212/493 (43%), Positives = 278/493 (56%), Gaps = 17/493 (3%)
 Frame = +2

Query: 743  VREGKPSAVSFSAEPEIFVNKEIPIRATSNYIEQPTMSSLNGKGPLKVQPSSGIEIDERK 922
            V++GKP A S   +  I  NK+          E+           +K+Q      I   K
Sbjct: 387  VKQGKP-ATSQPVDDNILENKKSQYEGLFGLKEE-----------IKLQSGVSNGIKHVK 434

Query: 923  SSNVFKGRLFRFSPSFPAARRGEIIQWINE----GGGQIFGDCIDIDSDFTVECHGV--V 1084
            S  VFKG+LFRFS SFP  +    +Q+I +      G +  D  + +  F VE HGV  +
Sbjct: 435  SPTVFKGKLFRFSSSFPEEQVSSSVQFIFKVALLSSGGVVADRNETNVHFIVERHGVPCL 494

Query: 1085 PSDAGSVYVSSHWVKSSLEDGRLLDVGSHILYSPLPCQIPFVSLEKFKICISQYNEKERS 1264
                 S YV+ HW+ S LEDG LLDV SHILYSPL C+IP    E +++C+S+Y+ KE+ 
Sbjct: 495  TKTIRSTYVTPHWIHSCLEDGCLLDVSSHILYSPLSCEIPLPGFEGYRVCVSRYDTKEKQ 554

Query: 1265 LLKNLCFVLGTKFTEKLTKSVTHLLCKFASGPKYEASCKWGMQSVTAEWLYECIKQNKVI 1444
            LL+NLC+VLG KFTEKL K VTHLLCKFA G KYEA+ +WG+  VTAEW+YEC  QNKV+
Sbjct: 555  LLRNLCYVLGGKFTEKLNKKVTHLLCKFADGDKYEAASRWGVHIVTAEWIYECAMQNKVV 614

Query: 1445 DPDPFHPKQATSQEREAGLCTMSQYPTQAFQMTSGDNASQLPIQSEELKNVQNESHPRKV 1624
            D   F+PK+ TSQER++GL ++SQYPT++F M SG++ SQ P Q + LKN+Q +   R +
Sbjct: 615  DLKRFYPKELTSQERQSGLNSLSQYPTESFSMPSGNDVSQYPDQWQHLKNMQTDPSTRCM 674

Query: 1625 VGFEETVPPSSCRKREASIAENPTSMLSSVSKQFDHGLTVLSTKNMEESAKVVSEFH--- 1795
                +  P  S +K  A ++EN     SS++ Q     T   + N+++S   +   +   
Sbjct: 675  ARDNKEFPNGSIKK--ARLSEN-----SSINHQLSDDATTPCSVNVKDSTDAIVNGNTTE 727

Query: 1796 ------DDVAAIEDLLEQTSTISDHMSTEISLFPFDGSLRGQASDCTIRDQATDFSIRGL 1957
                  D  AAIED LEQTS I +  S E              SDC      ++ S+ G 
Sbjct: 728  ATPVVPDVAAAIEDFLEQTSKIQEWKSQE-------------KSDCHENFMPSNSSMLGQ 774

Query: 1958 DDVDPSSYTKVQMDCINRPARNFDKINLPRTVATEAYDNFSETQTDSQIVGYAEDLSGRQ 2137
               DP S+       +NR  R  D        A   YDNFSETQTDSQ+VGY EDLSGRQ
Sbjct: 775  RHADPQSFPGPSKQWMNRVDRKDDSPPADAAAAKGLYDNFSETQTDSQVVGYEEDLSGRQ 834

Query: 2138 MIIDRV--RSSMT 2170
            MIIDRV  RSSMT
Sbjct: 835  MIIDRVRTRSSMT 847



 Score =  206 bits (525), Expect(2) = e-148
 Identities = 116/237 (48%), Positives = 152/237 (64%), Gaps = 4/237 (1%)
 Frame = +1

Query: 13  DKYVVAKQWGHILIVTRKWFDQSLSRRVCLNEESYPVQSTPASSLSISRKKARHSQETSS 192
           DKY VAK+WG I IV++KWF QS++RR CLNEESYPVQS  ASS  +S  K         
Sbjct: 136 DKYKVAKRWGCIHIVSKKWFHQSIARRACLNEESYPVQSNLASS--VSSLKTVEKNINGK 193

Query: 193 GISQCAKPSAGMASSSE----LCGPTISQDPEVTVSHNIFTVVSEVSMFNNDGEXXXXXX 360
           GI      S+ MAS+S+       P +  D E+ +  N+     EV     +G       
Sbjct: 194 GIRSSHFTSSYMASASDSETNFSAPDMEYDLEIPLP-NVHPTCLEVPPLPAEGSEPP--- 249

Query: 361 XXXXXXXNASEPNVDIPLNNCIANDSQTEDNDLYLSECRITIVGFEASELRKLVSIVRRG 540
                   A +   D    +CIA+DSQ+E+++LYLSECRI +VGFE SELRK+V +VR+G
Sbjct: 250 --------AEKLKNDSDFAHCIADDSQSENDNLYLSECRIMLVGFETSELRKVVDMVRQG 301

Query: 541 GGSRYMHFNEKLTHIVVGSPSEIEIRETRTLASRGIIHVVKKEWLEDCDREKKEFPV 711
           GGSRYM F+EKLTH+VVG+PS+IEI+E R LAS G+I++VK  WL++C R+KKE PV
Sbjct: 302 GGSRYMSFSEKLTHVVVGNPSDIEIKEARNLASFGVIYIVKTAWLDECTRKKKEVPV 358


>CDP16447.1 unnamed protein product [Coffea canephora]
          Length = 962

 Score =  421 bits (1083), Expect = e-130
 Identities = 233/480 (48%), Positives = 304/480 (63%), Gaps = 10/480 (2%)
 Frame = +2

Query: 761  SAVSFSAEPEIFV--NKEIPIRATSNYIEQPTMSSLNGKGPLKVQPSSGIEIDERKSSNV 934
            S VSF    E++   N+E+    T N  +Q   +          Q S+  + D R S+NV
Sbjct: 510  SGVSFEKRKEVYSIRNEEMSWVNTGNLAKQQQST----------QKSASHDRDNRISANV 559

Query: 935  FKGRLFRFSPSFPAARRGEIIQWINEGGGQIFGDCIDIDSDFTVECHGVVPSD---AGSV 1105
            F G+LF FS SFPA +R EI++W+N+GGG++  + ++ ++ F VECHGVVPS+   +GS 
Sbjct: 560  FAGKLFCFSGSFPADQRAEIVEWVNQGGGEVVENLVEGNTYFIVECHGVVPSETDFSGSK 619

Query: 1106 YVSSHWVKSSLEDGRLLDVGSHILYSPLPCQIPFVSLEKFKICISQYNEKERSLLKNLCF 1285
            YVSSHW++SSL DG LLDV SHILYSPLPCQ+PF+S + F+ C+SQY+EKER LL+NLCF
Sbjct: 620  YVSSHWIRSSLMDGHLLDVSSHILYSPLPCQVPFMSFKCFRFCVSQYDEKERLLLRNLCF 679

Query: 1286 VLGTKFTEKLTKSVTHLLCKFASGPKYEASCKWGMQSVTAEWLYECIKQNKVIDPDPFHP 1465
            +LG +F EKLTK VTHLLCKFASGPKYEA+CKWG+Q VT+EW+YEC+KQNKV+ P PF P
Sbjct: 680  ILGVQFVEKLTKKVTHLLCKFASGPKYEAACKWGIQPVTSEWIYECVKQNKVVSPGPFCP 739

Query: 1466 KQATSQEREAGLCTMSQYPTQAFQMTSGDNASQLPIQSEELKNVQNESHPRKVVGFEETV 1645
            K+ATSQ+RE G+CTM+QYPTQ   + SGD+ASQLP  S+E K+V+ E+  +K    EE  
Sbjct: 740  KEATSQDRETGVCTMTQYPTQGIGIISGDDASQLPRHSQECKSVETEAFTKK---SEEIN 796

Query: 1646 PPSSCRKREASIAENPTSMLSSVSKQFDHGLTVLSTKN---MEESAKVVSEFHDDVAAIE 1816
             P  C K+  +   + T   S       H +  +S       E ++KV +   D  AAIE
Sbjct: 797  YPIGCLKKARTFEADKTK-CSFSEANLTHSICRVSPMEEDVTENASKVTTMVPDVAAAIE 855

Query: 1817 DLLEQTSTISDHMSTEISLFPFDGSLRGQASDCTIRDQATDFSIRGLDDVDPSSYTKVQM 1996
            DLLEQTS I D  S                S C      +D ++ G D  +P S   +  
Sbjct: 856  DLLEQTSKIHDQQSP-------------VRSTCGTSIFTSDCTVLGQDRGEPQSALGLPK 902

Query: 1997 DCINRPARNFDKINLPRTVATEAYDNFSETQTDSQIVGYAEDLSGRQMIIDRV--RSSMT 2170
               NR  +  D  N      T  YD F+ET T+SQ+VGYA+DLSGRQMIIDRV  R+SMT
Sbjct: 903  HWKNRFDKKDDSHNPQEDARTNDYDGFTETPTESQVVGYADDLSGRQMIIDRVRTRNSMT 962



 Score =  242 bits (617), Expect = 4e-64
 Identities = 129/239 (53%), Positives = 162/239 (67%), Gaps = 2/239 (0%)
 Frame = +1

Query: 1   APEGDKYVVAKQWGHILIVTRKWFDQSLSRRVCLNEESYPVQSTPASSLSISRKKARHSQ 180
           APEGDKY VAK+WGHI I++RKWFDQS++RR CLNEESYPVQ    SS+   RK A  SQ
Sbjct: 234 APEGDKYKVAKRWGHIHIISRKWFDQSVARRACLNEESYPVQG---SSMKTVRKMAMPSQ 290

Query: 181 ETSSGISQCAKPSAGMASSSELCGPTISQDP--EVTVSHNIFTVVSEVSMFNNDGEXXXX 354
           + S G SQC   SAG AS   +       +P  E  +SH++ +   +   F  + +    
Sbjct: 291 DKSLGNSQCEASSAGTASDPHVRQYAQKPEPSSEANISHDMSSAFCDAPTFTREEDNGQ- 349

Query: 355 XXXXXXXXXNASEPNVDIPLNNCIANDSQTEDNDLYLSECRITIVGFEASELRKLVSIVR 534
                    +A +   +  ++ C+A+DSQTED DLYLS CRI +VGF A  +RKLVS+VR
Sbjct: 350 ---------SAEQLKNNSNVDGCVADDSQTED-DLYLSVCRIMLVGFNADNMRKLVSMVR 399

Query: 535 RGGGSRYMHFNEKLTHIVVGSPSEIEIRETRTLASRGIIHVVKKEWLEDCDREKKEFPV 711
           RGGGSRYM FNEKLTHI+VG+PSE EI+E R LA+ G+I+VVK EWLEDCDR+KKE PV
Sbjct: 400 RGGGSRYMSFNEKLTHIIVGTPSESEIKEVRNLAALGVIYVVKSEWLEDCDRQKKEVPV 458


>XP_016440871.1 PREDICTED: uncharacterized protein LOC107766582 [Nicotiana tabacum]
          Length = 489

 Score =  396 bits (1018), Expect = e-126
 Identities = 219/433 (50%), Positives = 276/433 (63%), Gaps = 6/433 (1%)
 Frame = +2

Query: 881  KVQPSSGIEIDERKSSNVFKGRLFRFSPSFPAARRGEIIQWINEGGGQIFGDCIDIDSDF 1060
            K+   SG  ++ RK S+VF+GR F FS SFP  RR EI++W+++GGG +  D  + +  F
Sbjct: 64   KLLNESGCAVNGRKPSSVFEGRRFCFSASFPVDRRAEIVEWVSQGGGVVVEDQTETNVHF 123

Query: 1061 TVECHGVVPSD---AGSVYVSSHWVKSSLEDGRLLDVGSHILYSPLPCQIPFVSLEKFKI 1231
            TVECHG + S+   A + +VSSHW+KS LEDG LLDVGSHILYSPLPC++PF + + F+ 
Sbjct: 124  TVECHGTLCSEKDGAAATFVSSHWIKSCLEDGCLLDVGSHILYSPLPCRVPFPAFQSFRF 183

Query: 1232 CISQYNEKERSLLKNLCFVLGTKFTEKLTKSVTHLLCKFASGPKYEASCKWGMQSVTAEW 1411
            C+SQY+EKER LL+NLCF +G KF EKLTK VTHLLCKF SGPKYE +CKWG+Q VT EW
Sbjct: 184  CVSQYDEKERQLLRNLCFTIGAKFAEKLTKRVTHLLCKFISGPKYEVACKWGIQPVTCEW 243

Query: 1412 LYECIKQNKVIDPDPFHPKQATSQEREAGLCTMSQYPTQAFQMTSGDNASQLPIQSEELK 1591
            +YECIK NK++ PDPF+PK+ TS++REAG+CT SQ+PTQA +MTSGD +SQ   Q +EL 
Sbjct: 244  IYECIKLNKIVSPDPFYPKEVTSEDREAGVCTTSQFPTQAVRMTSGDTSSQPQSQPQELI 303

Query: 1592 NVQNESHPRKVVGFEETVPPSSCRKR-EASIAENPTSMLSSVSKQFDHGL-TVLSTKNME 1765
            N++ E+   + +  EE    S   K+    + E     L+ VS + +    T    KNM 
Sbjct: 304  NLRTEAFAGRSIANEEMKHSSRWNKKARLMVVEETNCSLTCVSNENNAFCGTNPPEKNMI 363

Query: 1766 ESAKVVSEFHDDV-AAIEDLLEQTSTISDHMSTEISLFPFDGSLRGQASDCTIRDQATDF 1942
             S K  S    DV AAIEDLLEQTS I D  S   S    D  L    S C I  Q    
Sbjct: 364  GSTKEDSSAVPDVAAAIEDLLEQTSKIHDQKSP--SRIECDKEL--FTSGCNILAQGHG- 418

Query: 1943 SIRGLDDVDPSSYTKVQMDCINRPARNFDKINLPRTVATEAYDNFSETQTDSQIVGYAED 2122
                    D  +   +  D  NR  +  D            YD+FSETQTDSQ+VGYAED
Sbjct: 419  --------DHHTTLGLSNDWTNRFEKKDDSHGHSGDATANVYDHFSETQTDSQVVGYAED 470

Query: 2123 LSGRQMIIDRVRS 2161
            LSGRQMIIDRVR+
Sbjct: 471  LSGRQMIIDRVRT 483


>XP_015063139.1 PREDICTED: DNA topoisomerase 2-binding protein 1 isoform X2 [Solanum
            pennellii]
          Length = 894

 Score =  400 bits (1027), Expect = e-123
 Identities = 220/443 (49%), Positives = 279/443 (62%), Gaps = 10/443 (2%)
 Frame = +2

Query: 863  NGKGPLKVQPSSGIEIDERKSSNVFKGRLFRFSPSFPAARRGEIIQWINEGGGQIFGDCI 1042
            NGK   K+   S   ++ RK S+VF+GR F FS SFPA RR EI++W+N+GGG +  D  
Sbjct: 463  NGKEEFKIPNESSCAVNGRKPSSVFEGRRFCFSASFPADRRAEIVEWVNQGGGVVVKDQY 522

Query: 1043 DIDSDFTVECHGVVPSD---AGSVYVSSHWVKSSLEDGRLLDVGSHILYSPLPCQIPFVS 1213
            + +  FTVECHG++ S+   A + +VSSHW+KS LEDG LLDVG HILYSPLPCQ+PF +
Sbjct: 523  ETNLHFTVECHGLLHSEKDGAATTFVSSHWIKSCLEDGCLLDVGDHILYSPLPCQVPFPA 582

Query: 1214 LEKFKICISQYNEKERSLLKNLCFVLGTKFTEKLTKSVTHLLCKFASGPKYEASCKWGMQ 1393
             + F++C+SQY+EKER LL+NLCF +G KF EKLTK VTHLLCKF  GPKYEA+CKWG+Q
Sbjct: 583  FKSFRLCVSQYDEKERQLLRNLCFTIGAKFVEKLTKKVTHLLCKFTDGPKYEAACKWGIQ 642

Query: 1394 SVTAEWLYECIKQNKVIDPDPFHPKQATSQEREAGLCTMSQYPTQAFQMTSGDNASQLPI 1573
             VT EW+YECIKQNK++  DPF+PK+ TS++REAG CT+SQ+PTQAF M SGD  SQ   
Sbjct: 643  PVTCEWIYECIKQNKIVSADPFYPKEVTSEDREAGACTVSQFPTQAFGMISGDTTSQPQT 702

Query: 1574 QSEELKNVQNESHPRKVVGFEETVPPSSCRKR-EASIAENPTSMLSSVSKQFDHGLTVL- 1747
            Q++EL NV+ E+   +    EE    S   K+    + E P   LS   K+ +       
Sbjct: 703  QTQELVNVRTEAFADRNTAKEEKKYSSRWNKKARLLVVEEPKCSLSCSPKESNAFCGASP 762

Query: 1748 STKNMEESAKVVSEFHDDV-AAIEDLLEQTSTISDHMSTEISLFPFDGSLRGQASDCTIR 1924
              KN+  S    S    DV AAIEDLLEQTS I D  S   S    D  L     +   +
Sbjct: 763  PEKNLTGSTNEGSSAVPDVAAAIEDLLEQTSKIHDQKSPSRS--ECDKELFTSGCNNLAQ 820

Query: 1925 DQATDFSIRGLDDVDPSSYTKVQMDCINRPARNFDKINLPRTVATEA----YDNFSETQT 2092
                + +  GL                N     F+K +   T + +A    YD+FSETQT
Sbjct: 821  GHGDNHATLGLS---------------NHWTNRFEKEDETHTHSGDATANVYDHFSETQT 865

Query: 2093 DSQIVGYAEDLSGRQMIIDRVRS 2161
            DSQ+VGYAEDLSGRQMIIDRVR+
Sbjct: 866  DSQVVGYAEDLSGRQMIIDRVRT 888



 Score =  217 bits (553), Expect = 7e-56
 Identities = 121/247 (48%), Positives = 156/247 (63%), Gaps = 11/247 (4%)
 Frame = +1

Query: 4   PEGDKYVVAKQWGHILIVTRKWFDQSLSRRVCLNEESYPVQSTPASSLSISRKKARHSQE 183
           PEGDK+ VAK+WG I  VT++WF+QS++RR CLNEESYPVQ+  +++LS  R   +HS E
Sbjct: 133 PEGDKFKVAKRWGCIHTVTKRWFEQSVARRACLNEESYPVQAV-SNTLSTVRMTNQHSLE 191

Query: 184 TSSGISQCAKPSAGMASSSE--LCGPTISQDPEVTVSHNIFTVVSEVSMFNNDGEXXXXX 357
                 Q   PS   AS++E   C      D E T+S N+    S V +   + E     
Sbjct: 192 KGIRNLQ-GLPSLATASNAEPVFCSRVADSDLEATLSQNMSATSSYVPVVTKEEENSPAE 250

Query: 358 XXXXXXXXNASEP------NVDIPLNNC---IANDSQTEDNDLYLSECRITIVGFEASEL 510
                     S        + +   N C   +A+DS+T+DNDLYL++CRI IVGF ASE+
Sbjct: 251 FPKSDYSAPVSTKGEKSGASTEHEKNGCDVVVADDSETDDNDLYLADCRILIVGFNASEM 310

Query: 511 RKLVSIVRRGGGSRYMHFNEKLTHIVVGSPSEIEIRETRTLASRGIIHVVKKEWLEDCDR 690
           RKLV++VR+GGGSRYM F EKLTHI+ G+PSE EI+E R LA+ G+IHVVK  WLEDCDR
Sbjct: 311 RKLVNLVRKGGGSRYMSFGEKLTHIIAGNPSENEIKELRNLAALGVIHVVKSGWLEDCDR 370

Query: 691 EKKEFPV 711
           E KE PV
Sbjct: 371 ENKEVPV 377


>XP_010320796.1 PREDICTED: DNA topoisomerase 2-binding protein 1 isoform X2 [Solanum
            lycopersicum]
          Length = 892

 Score =  399 bits (1026), Expect = e-122
 Identities = 219/443 (49%), Positives = 279/443 (62%), Gaps = 10/443 (2%)
 Frame = +2

Query: 863  NGKGPLKVQPSSGIEIDERKSSNVFKGRLFRFSPSFPAARRGEIIQWINEGGGQIFGDCI 1042
            NGK   K+   S   ++ RK S+VF+GR F FS SFPA RR EI++W+N+GGG +  D  
Sbjct: 461  NGKEEFKIPNESSCAVNGRKPSSVFEGRRFCFSASFPADRRAEIVEWVNQGGGVVVKDQN 520

Query: 1043 DIDSDFTVECHGVVPSD---AGSVYVSSHWVKSSLEDGRLLDVGSHILYSPLPCQIPFVS 1213
            + +  FT+ECHG++ S+   A + +VSSHW+KS LEDG LLDVG HILYSPLPC++PF +
Sbjct: 521  ETNLHFTIECHGMLRSEKDGAATTFVSSHWIKSCLEDGCLLDVGDHILYSPLPCRVPFPA 580

Query: 1214 LEKFKICISQYNEKERSLLKNLCFVLGTKFTEKLTKSVTHLLCKFASGPKYEASCKWGMQ 1393
             + F++C+SQY+EKER LL+NLCF +G KF EKLTK VTHLLCKF  GPKYEA+CKWG+Q
Sbjct: 581  FKSFRLCVSQYDEKERQLLRNLCFTIGAKFVEKLTKKVTHLLCKFTDGPKYEAACKWGIQ 640

Query: 1394 SVTAEWLYECIKQNKVIDPDPFHPKQATSQEREAGLCTMSQYPTQAFQMTSGDNASQLPI 1573
             VT EW+YECIKQNK++  DPF+PK+ TS++REAG CT+SQ+PTQAF M SGD  SQ   
Sbjct: 641  PVTCEWIYECIKQNKIVSADPFYPKEVTSEDREAGACTVSQFPTQAFGMISGDTTSQPQT 700

Query: 1574 QSEELKNVQNESHPRKVVGFEETVPPSSCRKR-EASIAENPTSMLSSVSKQFDHGLTVL- 1747
            Q +EL NV+ E+   +    EE   PS   K+    + E P   LS   K+ +       
Sbjct: 701  QPQELVNVRTEAFAGRNTAKEEKKYPSRWNKKARLFVVEEPKCSLSCSPKESNAFCGASP 760

Query: 1748 STKNMEESAKVVSEFHDDV-AAIEDLLEQTSTISDHMSTEISLFPFDGSLRGQASDCTIR 1924
              KN+  S    S    DV AAIEDLLEQTS I D  S   S    D  L     +   +
Sbjct: 761  PEKNLTGSTNEGSSAVPDVAAAIEDLLEQTSKIHDQKSPSRS--ECDKELFTSGCNNLAQ 818

Query: 1925 DQATDFSIRGLDDVDPSSYTKVQMDCINRPARNFDKINLPRTVATEA----YDNFSETQT 2092
                + +  GL                N     F+K +   T + +A    YD+FSETQT
Sbjct: 819  GHGDNHATLGLS---------------NHWTNRFEKEDETHTHSGDATANVYDHFSETQT 863

Query: 2093 DSQIVGYAEDLSGRQMIIDRVRS 2161
            DSQ+VGYAEDLSGRQMIIDRVR+
Sbjct: 864  DSQVVGYAEDLSGRQMIIDRVRT 886



 Score =  214 bits (546), Expect = 5e-55
 Identities = 121/245 (49%), Positives = 155/245 (63%), Gaps = 9/245 (3%)
 Frame = +1

Query: 4   PEGDKYVVAKQWGHILIVTRKWFDQSLSRRVCLNEESYPVQSTPASSLSISRKKARHSQE 183
           PEGDK+ VAK+WG I  VT++WF+QS++RR CLNEESYPVQS  +++LSI R   +HS E
Sbjct: 133 PEGDKFKVAKRWGCIHTVTKRWFEQSVARRACLNEESYPVQSG-SNTLSIVRMTNQHSLE 191

Query: 184 TSSGISQCAKPSAGMASSSE--LCGPTISQDPEVTVSHNIFTVVSEVSMFNNDGEXXXXX 357
                 Q    S   AS++E   C      D E T+S N+    S V +   + E     
Sbjct: 192 KGIRNLQ-GLSSLATASNAEPVFCSRVADSDLEATLSQNMSGTSSYVPVVTKEEENSPAE 250

Query: 358 XXXXXXXXNAS----EPNVDIPLNNC---IANDSQTEDNDLYLSECRITIVGFEASELRK 516
                     S    +       + C   +A+DS+T+DNDLYL++CRI IVGF ASE+RK
Sbjct: 251 YPKSDYSAPVSTKGEKSGASTEHDGCDGVVADDSETDDNDLYLADCRILIVGFNASEMRK 310

Query: 517 LVSIVRRGGGSRYMHFNEKLTHIVVGSPSEIEIRETRTLASRGIIHVVKKEWLEDCDREK 696
           LV++VR+GGGSRYM F EKLTHI+ G+PSE EI+E R LA+ G+IHVVK  WLEDCDRE 
Sbjct: 311 LVNLVRKGGGSRYMSFGEKLTHIIAGNPSENEIKELRNLAALGVIHVVKSGWLEDCDREN 370

Query: 697 KEFPV 711
           KE PV
Sbjct: 371 KEVPV 375


>EEF42097.1 topbp1, putative [Ricinus communis]
          Length = 950

 Score =  400 bits (1027), Expect = e-122
 Identities = 222/480 (46%), Positives = 297/480 (61%), Gaps = 10/480 (2%)
 Frame = +2

Query: 752  GKPSAVSFSAE--PEIFVNKEIPIRATSNYIEQPTMSSLNG--KGPLKVQPSSGIEIDER 919
            GK S++  S E  PEI++++ I + AT    +Q   S +N   K   K QP+S  +   +
Sbjct: 473  GKTSSLENSREEKPEIYMSRSISLEATVRQSQQNIFSIVNDEKKSGKKTQPNSSCQ--NQ 530

Query: 920  KSSNVFKGRLFRFSPSFPAARRGEIIQWINEGGGQIFGDCIDIDSDFTVECHGVVPSDAG 1099
            K   VFKG++F FS SFPA RR EII+W+++GGG++  D    + +FT+ECHG +P   G
Sbjct: 531  KPLTVFKGKIFCFSNSFPADRRAEIIEWVSQGGGKMVEDHTKKNVNFTIECHGTIPRCMG 590

Query: 1100 ---SVYVSSHWVKSSLEDGRLLDVGSHILYSPLPCQIPFVSLEKFKICISQYNEKERSLL 1270
               + YVSSHWV+S LED  LLDVG HI+YSPLPCQIP    E F+ CISQY EK+R LL
Sbjct: 591  GSQTTYVSSHWVRSCLEDESLLDVGGHIIYSPLPCQIPLPGFENFRFCISQYEEKDRLLL 650

Query: 1271 KNLCFVLGTKFTEKLTKSVTHLLCKFASGPKYEASCKWGMQSVTAEWLYECIKQNKVIDP 1450
            +NLCFVLG KF EKLT+ VTHLLCKF +GPKYEA+CKWG+ S+T+EW+YEC++QN+V+  
Sbjct: 651  RNLCFVLGAKFVEKLTRKVTHLLCKFTNGPKYEAACKWGICSITSEWIYECVRQNEVVAL 710

Query: 1451 DPFHPKQATSQEREAGLCTMSQYPTQAFQMTSGDNASQLPIQSEELKNVQNESHPRKVVG 1630
            D F PK+ TSQ++EAGLCT+SQ+PTQA +M SG+N SQL  QS +L++   ++    +  
Sbjct: 711  DRFRPKEVTSQDQEAGLCTVSQFPTQAARMISGENPSQLISQSRDLRSAPTQTGSIGIFS 770

Query: 1631 FEETVPPSSCRKREASIAENPTSMLSSVSKQFDHGLTVLSTKNMEESAKVVSEFH---DD 1801
            F E    S+   ++A + ++     + +S   D  +  +++    +S       H   D 
Sbjct: 771  FGEDAQKSTKYSKKARLLKS-DDQEAQLSFHLDDPVYTINSTRGNDSKDTAGSSHGVPDV 829

Query: 1802 VAAIEDLLEQTSTISDHMSTEISLFPFDGSLRGQASDCTIRDQATDFSIRGLDDVDPSSY 1981
             AAIEDLLEQTS I D  S   S +    S+       TI        I G D     S 
Sbjct: 830  AAAIEDLLEQTSKIHDQKSLGKSEY----SMFASVESLTIEQLYPSDPILGEDHGGSHSV 885

Query: 1982 TKVQMDCINRPARNFDKINLPRTVATEAYDNFSETQTDSQIVGYAEDLSGRQMIIDRVRS 2161
              V    +NR  +  D  N  R V    YDNF+ETQT+SQ+V Y EDLSGRQMIIDRVR+
Sbjct: 886  IGVPNHWLNRTGKRDDLSNPSREVNRGVYDNFTETQTESQVVLYEEDLSGRQMIIDRVRT 945



 Score =  233 bits (595), Expect = 3e-61
 Identities = 131/241 (54%), Positives = 165/241 (68%), Gaps = 5/241 (2%)
 Frame = +1

Query: 4   PEGDKYVVAKQWGHILIVTRKWFDQSLSRRVCLNEESYPVQSTPASSLSISRKKARHSQE 183
           P GDKY VA++WGHI IV RKWFDQS++RR CLNEESYPVQ   ASS+  S   A+H   
Sbjct: 198 PAGDKYKVAQRWGHIHIVMRKWFDQSVARRACLNEESYPVQGGSASSIKKSSSMAQHIIG 257

Query: 184 TSSGISQCAKPSAGMASSS--ELCGPTISQ-DPEVTVSHNIFTVVSE--VSMFNNDGEXX 348
            S  +     PSA  A S+   L G  +S  D E T+S N+ ++ S+  VS+   D E  
Sbjct: 258 NSISV-----PSAAPAESNLPGLPGAGVSDLDLEPTLSQNMSSMFSDPPVSVKEWDNEVP 312

Query: 349 XXXXXXXXXXXNASEPNVDIPLNNCIANDSQTEDNDLYLSECRITIVGFEASELRKLVSI 528
                       A  P  +  L+ C+ANDSQ+ED+DLYLSECRI++VGFEASELRKLV++
Sbjct: 313 ------------AVHPTNETNLDGCVANDSQSEDSDLYLSECRISLVGFEASELRKLVNM 360

Query: 529 VRRGGGSRYMHFNEKLTHIVVGSPSEIEIRETRTLASRGIIHVVKKEWLEDCDREKKEFP 708
           VRRGGGSRY+ FN+KLTHIVVG+P+E+E +E R LA+ G+I VV+  WLEDCDR+KKE P
Sbjct: 361 VRRGGGSRYLSFNDKLTHIVVGAPTEVEKKELRGLAALGVIDVVRPTWLEDCDRQKKEVP 420

Query: 709 V 711
           V
Sbjct: 421 V 421


>XP_015063138.1 PREDICTED: DNA topoisomerase 2-binding protein 1 isoform X1 [Solanum
            pennellii]
          Length = 993

 Score =  400 bits (1027), Expect = e-122
 Identities = 220/443 (49%), Positives = 279/443 (62%), Gaps = 10/443 (2%)
 Frame = +2

Query: 863  NGKGPLKVQPSSGIEIDERKSSNVFKGRLFRFSPSFPAARRGEIIQWINEGGGQIFGDCI 1042
            NGK   K+   S   ++ RK S+VF+GR F FS SFPA RR EI++W+N+GGG +  D  
Sbjct: 562  NGKEEFKIPNESSCAVNGRKPSSVFEGRRFCFSASFPADRRAEIVEWVNQGGGVVVKDQY 621

Query: 1043 DIDSDFTVECHGVVPSD---AGSVYVSSHWVKSSLEDGRLLDVGSHILYSPLPCQIPFVS 1213
            + +  FTVECHG++ S+   A + +VSSHW+KS LEDG LLDVG HILYSPLPCQ+PF +
Sbjct: 622  ETNLHFTVECHGLLHSEKDGAATTFVSSHWIKSCLEDGCLLDVGDHILYSPLPCQVPFPA 681

Query: 1214 LEKFKICISQYNEKERSLLKNLCFVLGTKFTEKLTKSVTHLLCKFASGPKYEASCKWGMQ 1393
             + F++C+SQY+EKER LL+NLCF +G KF EKLTK VTHLLCKF  GPKYEA+CKWG+Q
Sbjct: 682  FKSFRLCVSQYDEKERQLLRNLCFTIGAKFVEKLTKKVTHLLCKFTDGPKYEAACKWGIQ 741

Query: 1394 SVTAEWLYECIKQNKVIDPDPFHPKQATSQEREAGLCTMSQYPTQAFQMTSGDNASQLPI 1573
             VT EW+YECIKQNK++  DPF+PK+ TS++REAG CT+SQ+PTQAF M SGD  SQ   
Sbjct: 742  PVTCEWIYECIKQNKIVSADPFYPKEVTSEDREAGACTVSQFPTQAFGMISGDTTSQPQT 801

Query: 1574 QSEELKNVQNESHPRKVVGFEETVPPSSCRKR-EASIAENPTSMLSSVSKQFDHGLTVL- 1747
            Q++EL NV+ E+   +    EE    S   K+    + E P   LS   K+ +       
Sbjct: 802  QTQELVNVRTEAFADRNTAKEEKKYSSRWNKKARLLVVEEPKCSLSCSPKESNAFCGASP 861

Query: 1748 STKNMEESAKVVSEFHDDV-AAIEDLLEQTSTISDHMSTEISLFPFDGSLRGQASDCTIR 1924
              KN+  S    S    DV AAIEDLLEQTS I D  S   S    D  L     +   +
Sbjct: 862  PEKNLTGSTNEGSSAVPDVAAAIEDLLEQTSKIHDQKSPSRS--ECDKELFTSGCNNLAQ 919

Query: 1925 DQATDFSIRGLDDVDPSSYTKVQMDCINRPARNFDKINLPRTVATEA----YDNFSETQT 2092
                + +  GL                N     F+K +   T + +A    YD+FSETQT
Sbjct: 920  GHGDNHATLGLS---------------NHWTNRFEKEDETHTHSGDATANVYDHFSETQT 964

Query: 2093 DSQIVGYAEDLSGRQMIIDRVRS 2161
            DSQ+VGYAEDLSGRQMIIDRVR+
Sbjct: 965  DSQVVGYAEDLSGRQMIIDRVRT 987



 Score =  217 bits (553), Expect = 1e-55
 Identities = 121/247 (48%), Positives = 156/247 (63%), Gaps = 11/247 (4%)
 Frame = +1

Query: 4   PEGDKYVVAKQWGHILIVTRKWFDQSLSRRVCLNEESYPVQSTPASSLSISRKKARHSQE 183
           PEGDK+ VAK+WG I  VT++WF+QS++RR CLNEESYPVQ+  +++LS  R   +HS E
Sbjct: 232 PEGDKFKVAKRWGCIHTVTKRWFEQSVARRACLNEESYPVQAV-SNTLSTVRMTNQHSLE 290

Query: 184 TSSGISQCAKPSAGMASSSE--LCGPTISQDPEVTVSHNIFTVVSEVSMFNNDGEXXXXX 357
                 Q   PS   AS++E   C      D E T+S N+    S V +   + E     
Sbjct: 291 KGIRNLQ-GLPSLATASNAEPVFCSRVADSDLEATLSQNMSATSSYVPVVTKEEENSPAE 349

Query: 358 XXXXXXXXNASEP------NVDIPLNNC---IANDSQTEDNDLYLSECRITIVGFEASEL 510
                     S        + +   N C   +A+DS+T+DNDLYL++CRI IVGF ASE+
Sbjct: 350 FPKSDYSAPVSTKGEKSGASTEHEKNGCDVVVADDSETDDNDLYLADCRILIVGFNASEM 409

Query: 511 RKLVSIVRRGGGSRYMHFNEKLTHIVVGSPSEIEIRETRTLASRGIIHVVKKEWLEDCDR 690
           RKLV++VR+GGGSRYM F EKLTHI+ G+PSE EI+E R LA+ G+IHVVK  WLEDCDR
Sbjct: 410 RKLVNLVRKGGGSRYMSFGEKLTHIIAGNPSENEIKELRNLAALGVIHVVKSGWLEDCDR 469

Query: 691 EKKEFPV 711
           E KE PV
Sbjct: 470 ENKEVPV 476


>XP_010320793.1 PREDICTED: DNA topoisomerase 2-binding protein 1 isoform X1 [Solanum
            lycopersicum]
          Length = 991

 Score =  399 bits (1026), Expect = e-121
 Identities = 219/443 (49%), Positives = 279/443 (62%), Gaps = 10/443 (2%)
 Frame = +2

Query: 863  NGKGPLKVQPSSGIEIDERKSSNVFKGRLFRFSPSFPAARRGEIIQWINEGGGQIFGDCI 1042
            NGK   K+   S   ++ RK S+VF+GR F FS SFPA RR EI++W+N+GGG +  D  
Sbjct: 560  NGKEEFKIPNESSCAVNGRKPSSVFEGRRFCFSASFPADRRAEIVEWVNQGGGVVVKDQN 619

Query: 1043 DIDSDFTVECHGVVPSD---AGSVYVSSHWVKSSLEDGRLLDVGSHILYSPLPCQIPFVS 1213
            + +  FT+ECHG++ S+   A + +VSSHW+KS LEDG LLDVG HILYSPLPC++PF +
Sbjct: 620  ETNLHFTIECHGMLRSEKDGAATTFVSSHWIKSCLEDGCLLDVGDHILYSPLPCRVPFPA 679

Query: 1214 LEKFKICISQYNEKERSLLKNLCFVLGTKFTEKLTKSVTHLLCKFASGPKYEASCKWGMQ 1393
             + F++C+SQY+EKER LL+NLCF +G KF EKLTK VTHLLCKF  GPKYEA+CKWG+Q
Sbjct: 680  FKSFRLCVSQYDEKERQLLRNLCFTIGAKFVEKLTKKVTHLLCKFTDGPKYEAACKWGIQ 739

Query: 1394 SVTAEWLYECIKQNKVIDPDPFHPKQATSQEREAGLCTMSQYPTQAFQMTSGDNASQLPI 1573
             VT EW+YECIKQNK++  DPF+PK+ TS++REAG CT+SQ+PTQAF M SGD  SQ   
Sbjct: 740  PVTCEWIYECIKQNKIVSADPFYPKEVTSEDREAGACTVSQFPTQAFGMISGDTTSQPQT 799

Query: 1574 QSEELKNVQNESHPRKVVGFEETVPPSSCRKR-EASIAENPTSMLSSVSKQFDHGLTVL- 1747
            Q +EL NV+ E+   +    EE   PS   K+    + E P   LS   K+ +       
Sbjct: 800  QPQELVNVRTEAFAGRNTAKEEKKYPSRWNKKARLFVVEEPKCSLSCSPKESNAFCGASP 859

Query: 1748 STKNMEESAKVVSEFHDDV-AAIEDLLEQTSTISDHMSTEISLFPFDGSLRGQASDCTIR 1924
              KN+  S    S    DV AAIEDLLEQTS I D  S   S    D  L     +   +
Sbjct: 860  PEKNLTGSTNEGSSAVPDVAAAIEDLLEQTSKIHDQKSPSRS--ECDKELFTSGCNNLAQ 917

Query: 1925 DQATDFSIRGLDDVDPSSYTKVQMDCINRPARNFDKINLPRTVATEA----YDNFSETQT 2092
                + +  GL                N     F+K +   T + +A    YD+FSETQT
Sbjct: 918  GHGDNHATLGLS---------------NHWTNRFEKEDETHTHSGDATANVYDHFSETQT 962

Query: 2093 DSQIVGYAEDLSGRQMIIDRVRS 2161
            DSQ+VGYAEDLSGRQMIIDRVR+
Sbjct: 963  DSQVVGYAEDLSGRQMIIDRVRT 985



 Score =  214 bits (546), Expect = 1e-54
 Identities = 121/245 (49%), Positives = 155/245 (63%), Gaps = 9/245 (3%)
 Frame = +1

Query: 4   PEGDKYVVAKQWGHILIVTRKWFDQSLSRRVCLNEESYPVQSTPASSLSISRKKARHSQE 183
           PEGDK+ VAK+WG I  VT++WF+QS++RR CLNEESYPVQS  +++LSI R   +HS E
Sbjct: 232 PEGDKFKVAKRWGCIHTVTKRWFEQSVARRACLNEESYPVQSG-SNTLSIVRMTNQHSLE 290

Query: 184 TSSGISQCAKPSAGMASSSE--LCGPTISQDPEVTVSHNIFTVVSEVSMFNNDGEXXXXX 357
                 Q    S   AS++E   C      D E T+S N+    S V +   + E     
Sbjct: 291 KGIRNLQ-GLSSLATASNAEPVFCSRVADSDLEATLSQNMSGTSSYVPVVTKEEENSPAE 349

Query: 358 XXXXXXXXNAS----EPNVDIPLNNC---IANDSQTEDNDLYLSECRITIVGFEASELRK 516
                     S    +       + C   +A+DS+T+DNDLYL++CRI IVGF ASE+RK
Sbjct: 350 YPKSDYSAPVSTKGEKSGASTEHDGCDGVVADDSETDDNDLYLADCRILIVGFNASEMRK 409

Query: 517 LVSIVRRGGGSRYMHFNEKLTHIVVGSPSEIEIRETRTLASRGIIHVVKKEWLEDCDREK 696
           LV++VR+GGGSRYM F EKLTHI+ G+PSE EI+E R LA+ G+IHVVK  WLEDCDRE 
Sbjct: 410 LVNLVRKGGGSRYMSFGEKLTHIIAGNPSENEIKELRNLAALGVIHVVKSGWLEDCDREN 469

Query: 697 KEFPV 711
           KE PV
Sbjct: 470 KEVPV 474


>XP_019167495.1 PREDICTED: DNA topoisomerase 2-binding protein 1-A isoform X2
            [Ipomoea nil]
          Length = 960

 Score =  398 bits (1022), Expect = e-121
 Identities = 227/448 (50%), Positives = 285/448 (63%), Gaps = 7/448 (1%)
 Frame = +2

Query: 842  QPTMSSLNGKGPLKVQPSSGIEIDERKSSNVFKGRLFRFSPSFPAARRGEIIQWINEGGG 1021
            QP   +LN K   K+Q SS    +++KSS VFKG+ F FS SFPA +R +II W+N+GGG
Sbjct: 515  QPQFCTLNSKEERKMQASSSTAAEDKKSSIVFKGKRFCFSSSFPANQRADIIGWVNQGGG 574

Query: 1022 QIFGDCIDIDSDFTVECHGVVPS--DAGSV-YVSSHWVKSSLEDGRLLDVGSHILYSPLP 1192
            ++  D I  D  FT+ECHG VPS  DA  V YVSSHW+KS LEDG LLDVGSHI+YSPLP
Sbjct: 575  ELVEDQIQRDVHFTIECHGAVPSQTDAARVTYVSSHWIKSCLEDGHLLDVGSHIIYSPLP 634

Query: 1193 CQIPFVSLEKFKICISQYNEKERSLLKNLCFVLGTKFTEKLTKSVTHLLCKFASGPKYEA 1372
            CQ+PF + + F++C+SQY+ KER LL+NLC VLG KF EKLT  VTHLLCKF SGPKY+A
Sbjct: 635  CQVPFPAFKGFRLCVSQYDVKERQLLRNLCVVLGAKFVEKLTTRVTHLLCKFTSGPKYDA 694

Query: 1373 SCKWGMQSVTAEWLYECIKQNKVIDPDPFHPKQATSQEREAGLCTMSQYPTQAFQMTSGD 1552
            +CK  +Q VT EW+YECIKQN ++ PDPF+PK+ T+++REAG+CT SQ+PTQA QM S D
Sbjct: 695  ACKLRIQPVTCEWIYECIKQNTIVAPDPFYPKEVTTEDREAGICTTSQFPTQAVQMISED 754

Query: 1553 NASQLPIQSEELKNVQNESHPRKVVGFEE-TVPPSSCRKREASIAENPTSMLSSVSKQFD 1729
            N SQL  QS+E+ +V +E+   +    EE    PSS +K      E     LSS+S Q D
Sbjct: 755  NVSQLQNQSKEINSVNSEAFTARSSAREEMKYLPSSSKKARLLADEKLKCPLSSLSNQSD 814

Query: 1730 --HGLTVLSTKNMEESAKVVSEFHDDVAAIEDLLEQTSTISDHMSTEISLFPFDGSLRGQ 1903
               G    + + M ES K  +   D    IED LEQTS   +H     S    D  L   
Sbjct: 815  AISGANPPNNRRM-ESTKDCAIMTDVANLIEDCLEQTS--KNHNPKSPSRNGCDKDL--F 869

Query: 1904 ASDCTIRDQATDFSIRGLDDVDPSSYTKVQMDCINRPARNFDKINLPRTV-ATEAYDNFS 2080
             S+CT         I G D  +P S  ++     NR  +  D   L   V AT  YD FS
Sbjct: 870  TSECT---------ILGQDHAEPQSALRLSEHWTNRFDKKDDSQPLHEDVPATAFYDGFS 920

Query: 2081 ETQTDSQIVGYAEDLSGRQMIIDRVRSS 2164
            + QT+SQ+V YA+DLSG QMIIDRVR+S
Sbjct: 921  DPQTESQVVSYAQDLSGMQMIIDRVRTS 948



 Score =  205 bits (522), Expect = 1e-51
 Identities = 115/237 (48%), Positives = 145/237 (61%)
 Frame = +1

Query: 1   APEGDKYVVAKQWGHILIVTRKWFDQSLSRRVCLNEESYPVQSTPASSLSISRKKARHSQ 180
           AP GDKY VAK WGHI IVT++W DQS++R  CLNEESY +Q + AS  S+ R K RHS 
Sbjct: 231 APVGDKYNVAKSWGHIRIVTKRWLDQSVARGACLNEESYRIQGSSASMNSV-RIKNRHSL 289

Query: 181 ETSSGISQCAKPSAGMASSSELCGPTISQDPEVTVSHNIFTVVSEVSMFNNDGEXXXXXX 360
           E    I      S    S+S      +  D   T   N  +  S    F+   E      
Sbjct: 290 ENV--IESVQSMSTATVSNSH----AVDSDMGATDCQNTSSF-SGAPFFSKGDESDAP-- 340

Query: 361 XXXXXXXNASEPNVDIPLNNCIANDSQTEDNDLYLSECRITIVGFEASELRKLVSIVRRG 540
                     +   +   + C+A DSQT+DNDLYLS+CR+ I+GF A E+RKLV++VR+G
Sbjct: 341 --------TEQQKNNTNFDGCVAGDSQTDDNDLYLSDCRLLILGFSAPEMRKLVNMVRKG 392

Query: 541 GGSRYMHFNEKLTHIVVGSPSEIEIRETRTLASRGIIHVVKKEWLEDCDREKKEFPV 711
           GGSRYM F++KLTHI+VGSPSEIE +E R LA+ G+IHVVK +WL DC  EKKE PV
Sbjct: 393 GGSRYMSFSDKLTHIIVGSPSEIETKEIRNLAALGVIHVVKPDWLADCISEKKEVPV 449


>XP_009788829.1 PREDICTED: DNA topoisomerase 2-binding protein 1 isoform X3
            [Nicotiana sylvestris]
          Length = 985

 Score =  397 bits (1021), Expect = e-121
 Identities = 219/433 (50%), Positives = 277/433 (63%), Gaps = 6/433 (1%)
 Frame = +2

Query: 881  KVQPSSGIEIDERKSSNVFKGRLFRFSPSFPAARRGEIIQWINEGGGQIFGDCIDIDSDF 1060
            K+   SG  ++ RK S+VF+GR F FS SFP  RR EI++W+++GGG +  D  + +  F
Sbjct: 560  KLLNESGCAVNGRKPSSVFEGRRFCFSASFPVDRRAEIVEWVSQGGGVVVEDQTETNVHF 619

Query: 1061 TVECHGVVPSD---AGSVYVSSHWVKSSLEDGRLLDVGSHILYSPLPCQIPFVSLEKFKI 1231
            TVECHG + S+   A + +VSSHW+KS LEDG LLDVGSHILYSPLPC++PF + + F+ 
Sbjct: 620  TVECHGTLCSEKDGAAATFVSSHWIKSCLEDGCLLDVGSHILYSPLPCRVPFPAFQSFRF 679

Query: 1232 CISQYNEKERSLLKNLCFVLGTKFTEKLTKSVTHLLCKFASGPKYEASCKWGMQSVTAEW 1411
            C+SQY+EKER LL+NLCF +G KF EKLTK VTHLLCKF SGPKYE +CKWG+Q VT EW
Sbjct: 680  CVSQYDEKERQLLRNLCFTIGAKFAEKLTKRVTHLLCKFISGPKYEVACKWGIQPVTCEW 739

Query: 1412 LYECIKQNKVIDPDPFHPKQATSQEREAGLCTMSQYPTQAFQMTSGDNASQLPIQSEELK 1591
            +YECIK NK++ PDPF+PK+ TS++REAG+CT SQ+PTQA +MTSGD +SQ   Q +EL 
Sbjct: 740  IYECIKLNKIVSPDPFYPKEVTSEDREAGVCTTSQFPTQAVRMTSGDTSSQPQSQPQELI 799

Query: 1592 NVQNESHPRKVVGFEETVPPSSCRKR-EASIAENPTSMLSSVSKQFDHGL-TVLSTKNME 1765
            N++ E+   + +  EE    S   K+    + E     L+ VS + +    T    KNM 
Sbjct: 800  NLRTEAFAGRSIAKEEMKHSSRWNKKARLMVVEETNCSLTCVSNENNAFCGTNPPEKNMI 859

Query: 1766 ESAKVVSEFHDDV-AAIEDLLEQTSTISDHMSTEISLFPFDGSLRGQASDCTIRDQATDF 1942
             S K  S    DV AAIEDLLEQTS I D  S   S    D  L    S C I  Q  + 
Sbjct: 860  GSTKEGSSAVPDVAAAIEDLLEQTSKIHDQKSP--SRIECDKEL--FTSGCNILAQGHE- 914

Query: 1943 SIRGLDDVDPSSYTKVQMDCINRPARNFDKINLPRTVATEAYDNFSETQTDSQIVGYAED 2122
                    D  +   +  D  NR  +  D            YD+FSETQTDSQ+VGYAED
Sbjct: 915  --------DHHTTLGLSNDWTNRFEKKDDSHGHSGDATANVYDHFSETQTDSQVVGYAED 966

Query: 2123 LSGRQMIIDRVRS 2161
            LSGRQMIIDRVR+
Sbjct: 967  LSGRQMIIDRVRT 979



 Score =  212 bits (539), Expect = 9e-54
 Identities = 118/255 (46%), Positives = 159/255 (62%), Gaps = 18/255 (7%)
 Frame = +1

Query: 1   APEGDKYVVAKQWGHILIVTRKWFDQSLSRRVCLNEESYPVQSTPASSLSISRKKARHSQ 180
           APEG+KY VAK+WGHI  VT++WFDQS++RR CL+EESYPVQ+   ++++  R   +HS 
Sbjct: 221 APEGEKYKVAKRWGHIHTVTKRWFDQSVARRACLDEESYPVQAGSPNTMTTLRMTNQHSL 280

Query: 181 ETS----SGISQCAKPSAG-----MASSSELCGPTISQD-PEVTVSHNIFTVVSEVSMFN 330
           E       G+S  A PS         +S      T+SQD P+  V         EV++  
Sbjct: 281 EKGMRNLQGLSSLATPSNAEPVLCSGASDSYVEATLSQDMPDTPV-----LTKKEVNLAP 335

Query: 331 NDGEXXXXXXXXXXXXXNASEPNVDIPLNNC---IANDSQTEDNDLYLSECRITIVGFEA 501
            +                +  P ++   N+C   +A+D+Q +DND YL++CRI IVGF A
Sbjct: 336 AENPKSDYSAPVSTKNEQSGAP-IEQEQNDCDGGVADDTQADDNDFYLADCRILIVGFNA 394

Query: 502 SELRKLVSIVRRGGGSRYMHFNEKLTHIVVGSPSE-----IEIRETRTLASRGIIHVVKK 666
           SE+RKLV++VR+GGGSRYM F EKLTHI+ G+PSE      EI+E R LA+ G++HVVK 
Sbjct: 395 SEMRKLVNLVRKGGGSRYMSFGEKLTHIIAGNPSEKLLSCSEIKELRNLAALGVVHVVKS 454

Query: 667 EWLEDCDREKKEFPV 711
           EWL+DCDREKKE PV
Sbjct: 455 EWLQDCDREKKEVPV 469


>XP_009788828.1 PREDICTED: DNA topoisomerase 2-binding protein 1 isoform X2
            [Nicotiana sylvestris]
          Length = 990

 Score =  397 bits (1021), Expect = e-121
 Identities = 219/433 (50%), Positives = 277/433 (63%), Gaps = 6/433 (1%)
 Frame = +2

Query: 881  KVQPSSGIEIDERKSSNVFKGRLFRFSPSFPAARRGEIIQWINEGGGQIFGDCIDIDSDF 1060
            K+   SG  ++ RK S+VF+GR F FS SFP  RR EI++W+++GGG +  D  + +  F
Sbjct: 565  KLLNESGCAVNGRKPSSVFEGRRFCFSASFPVDRRAEIVEWVSQGGGVVVEDQTETNVHF 624

Query: 1061 TVECHGVVPSD---AGSVYVSSHWVKSSLEDGRLLDVGSHILYSPLPCQIPFVSLEKFKI 1231
            TVECHG + S+   A + +VSSHW+KS LEDG LLDVGSHILYSPLPC++PF + + F+ 
Sbjct: 625  TVECHGTLCSEKDGAAATFVSSHWIKSCLEDGCLLDVGSHILYSPLPCRVPFPAFQSFRF 684

Query: 1232 CISQYNEKERSLLKNLCFVLGTKFTEKLTKSVTHLLCKFASGPKYEASCKWGMQSVTAEW 1411
            C+SQY+EKER LL+NLCF +G KF EKLTK VTHLLCKF SGPKYE +CKWG+Q VT EW
Sbjct: 685  CVSQYDEKERQLLRNLCFTIGAKFAEKLTKRVTHLLCKFISGPKYEVACKWGIQPVTCEW 744

Query: 1412 LYECIKQNKVIDPDPFHPKQATSQEREAGLCTMSQYPTQAFQMTSGDNASQLPIQSEELK 1591
            +YECIK NK++ PDPF+PK+ TS++REAG+CT SQ+PTQA +MTSGD +SQ   Q +EL 
Sbjct: 745  IYECIKLNKIVSPDPFYPKEVTSEDREAGVCTTSQFPTQAVRMTSGDTSSQPQSQPQELI 804

Query: 1592 NVQNESHPRKVVGFEETVPPSSCRKR-EASIAENPTSMLSSVSKQFDHGL-TVLSTKNME 1765
            N++ E+   + +  EE    S   K+    + E     L+ VS + +    T    KNM 
Sbjct: 805  NLRTEAFAGRSIAKEEMKHSSRWNKKARLMVVEETNCSLTCVSNENNAFCGTNPPEKNMI 864

Query: 1766 ESAKVVSEFHDDV-AAIEDLLEQTSTISDHMSTEISLFPFDGSLRGQASDCTIRDQATDF 1942
             S K  S    DV AAIEDLLEQTS I D  S   S    D  L    S C I  Q  + 
Sbjct: 865  GSTKEGSSAVPDVAAAIEDLLEQTSKIHDQKSP--SRIECDKEL--FTSGCNILAQGHE- 919

Query: 1943 SIRGLDDVDPSSYTKVQMDCINRPARNFDKINLPRTVATEAYDNFSETQTDSQIVGYAED 2122
                    D  +   +  D  NR  +  D            YD+FSETQTDSQ+VGYAED
Sbjct: 920  --------DHHTTLGLSNDWTNRFEKKDDSHGHSGDATANVYDHFSETQTDSQVVGYAED 971

Query: 2123 LSGRQMIIDRVRS 2161
            LSGRQMIIDRVR+
Sbjct: 972  LSGRQMIIDRVRT 984



 Score =  218 bits (554), Expect = 1e-55
 Identities = 118/250 (47%), Positives = 159/250 (63%), Gaps = 13/250 (5%)
 Frame = +1

Query: 1   APEGDKYVVAKQWGHILIVTRKWFDQSLSRRVCLNEESYPVQSTPASSLSISRKKARHSQ 180
           APEG+KY VAK+WGHI  VT++WFDQS++RR CL+EESYPVQ+   ++++  R   +HS 
Sbjct: 231 APEGEKYKVAKRWGHIHTVTKRWFDQSVARRACLDEESYPVQAGSPNTMTTLRMTNQHSL 290

Query: 181 ETS----SGISQCAKPSAG-----MASSSELCGPTISQD-PEVTVSHNIFTVVSEVSMFN 330
           E       G+S  A PS         +S      T+SQD P+  V         EV++  
Sbjct: 291 EKGMRNLQGLSSLATPSNAEPVLCSGASDSYVEATLSQDMPDTPV-----LTKKEVNLAP 345

Query: 331 NDGEXXXXXXXXXXXXXNASEPNVDIPLNNC---IANDSQTEDNDLYLSECRITIVGFEA 501
            +                +  P ++   N+C   +A+D+Q +DND YL++CRI IVGF A
Sbjct: 346 AENPKSDYSAPVSTKNEQSGAP-IEQEQNDCDGGVADDTQADDNDFYLADCRILIVGFNA 404

Query: 502 SELRKLVSIVRRGGGSRYMHFNEKLTHIVVGSPSEIEIRETRTLASRGIIHVVKKEWLED 681
           SE+RKLV++VR+GGGSRYM F EKLTHI+ G+PSE EI+E R LA+ G++HVVK EWL+D
Sbjct: 405 SEMRKLVNLVRKGGGSRYMSFGEKLTHIIAGNPSENEIKELRNLAALGVVHVVKSEWLQD 464

Query: 682 CDREKKEFPV 711
           CDREKKE PV
Sbjct: 465 CDREKKEVPV 474


>XP_009788827.1 PREDICTED: DNA topoisomerase 2-binding protein 1 isoform X1
            [Nicotiana sylvestris]
          Length = 995

 Score =  397 bits (1021), Expect = e-121
 Identities = 219/433 (50%), Positives = 277/433 (63%), Gaps = 6/433 (1%)
 Frame = +2

Query: 881  KVQPSSGIEIDERKSSNVFKGRLFRFSPSFPAARRGEIIQWINEGGGQIFGDCIDIDSDF 1060
            K+   SG  ++ RK S+VF+GR F FS SFP  RR EI++W+++GGG +  D  + +  F
Sbjct: 570  KLLNESGCAVNGRKPSSVFEGRRFCFSASFPVDRRAEIVEWVSQGGGVVVEDQTETNVHF 629

Query: 1061 TVECHGVVPSD---AGSVYVSSHWVKSSLEDGRLLDVGSHILYSPLPCQIPFVSLEKFKI 1231
            TVECHG + S+   A + +VSSHW+KS LEDG LLDVGSHILYSPLPC++PF + + F+ 
Sbjct: 630  TVECHGTLCSEKDGAAATFVSSHWIKSCLEDGCLLDVGSHILYSPLPCRVPFPAFQSFRF 689

Query: 1232 CISQYNEKERSLLKNLCFVLGTKFTEKLTKSVTHLLCKFASGPKYEASCKWGMQSVTAEW 1411
            C+SQY+EKER LL+NLCF +G KF EKLTK VTHLLCKF SGPKYE +CKWG+Q VT EW
Sbjct: 690  CVSQYDEKERQLLRNLCFTIGAKFAEKLTKRVTHLLCKFISGPKYEVACKWGIQPVTCEW 749

Query: 1412 LYECIKQNKVIDPDPFHPKQATSQEREAGLCTMSQYPTQAFQMTSGDNASQLPIQSEELK 1591
            +YECIK NK++ PDPF+PK+ TS++REAG+CT SQ+PTQA +MTSGD +SQ   Q +EL 
Sbjct: 750  IYECIKLNKIVSPDPFYPKEVTSEDREAGVCTTSQFPTQAVRMTSGDTSSQPQSQPQELI 809

Query: 1592 NVQNESHPRKVVGFEETVPPSSCRKR-EASIAENPTSMLSSVSKQFDHGL-TVLSTKNME 1765
            N++ E+   + +  EE    S   K+    + E     L+ VS + +    T    KNM 
Sbjct: 810  NLRTEAFAGRSIAKEEMKHSSRWNKKARLMVVEETNCSLTCVSNENNAFCGTNPPEKNMI 869

Query: 1766 ESAKVVSEFHDDV-AAIEDLLEQTSTISDHMSTEISLFPFDGSLRGQASDCTIRDQATDF 1942
             S K  S    DV AAIEDLLEQTS I D  S   S    D  L    S C I  Q  + 
Sbjct: 870  GSTKEGSSAVPDVAAAIEDLLEQTSKIHDQKSP--SRIECDKEL--FTSGCNILAQGHE- 924

Query: 1943 SIRGLDDVDPSSYTKVQMDCINRPARNFDKINLPRTVATEAYDNFSETQTDSQIVGYAED 2122
                    D  +   +  D  NR  +  D            YD+FSETQTDSQ+VGYAED
Sbjct: 925  --------DHHTTLGLSNDWTNRFEKKDDSHGHSGDATANVYDHFSETQTDSQVVGYAED 976

Query: 2123 LSGRQMIIDRVRS 2161
            LSGRQMIIDRVR+
Sbjct: 977  LSGRQMIIDRVRT 989



 Score =  212 bits (539), Expect = 9e-54
 Identities = 118/255 (46%), Positives = 159/255 (62%), Gaps = 18/255 (7%)
 Frame = +1

Query: 1   APEGDKYVVAKQWGHILIVTRKWFDQSLSRRVCLNEESYPVQSTPASSLSISRKKARHSQ 180
           APEG+KY VAK+WGHI  VT++WFDQS++RR CL+EESYPVQ+   ++++  R   +HS 
Sbjct: 231 APEGEKYKVAKRWGHIHTVTKRWFDQSVARRACLDEESYPVQAGSPNTMTTLRMTNQHSL 290

Query: 181 ETS----SGISQCAKPSAG-----MASSSELCGPTISQD-PEVTVSHNIFTVVSEVSMFN 330
           E       G+S  A PS         +S      T+SQD P+  V         EV++  
Sbjct: 291 EKGMRNLQGLSSLATPSNAEPVLCSGASDSYVEATLSQDMPDTPV-----LTKKEVNLAP 345

Query: 331 NDGEXXXXXXXXXXXXXNASEPNVDIPLNNC---IANDSQTEDNDLYLSECRITIVGFEA 501
            +                +  P ++   N+C   +A+D+Q +DND YL++CRI IVGF A
Sbjct: 346 AENPKSDYSAPVSTKNEQSGAP-IEQEQNDCDGGVADDTQADDNDFYLADCRILIVGFNA 404

Query: 502 SELRKLVSIVRRGGGSRYMHFNEKLTHIVVGSPSE-----IEIRETRTLASRGIIHVVKK 666
           SE+RKLV++VR+GGGSRYM F EKLTHI+ G+PSE      EI+E R LA+ G++HVVK 
Sbjct: 405 SEMRKLVNLVRKGGGSRYMSFGEKLTHIIAGNPSEKLLSCSEIKELRNLAALGVVHVVKS 464

Query: 667 EWLEDCDREKKEFPV 711
           EWL+DCDREKKE PV
Sbjct: 465 EWLQDCDREKKEVPV 479


>XP_015575415.1 PREDICTED: DNA topoisomerase 2-binding protein 1-A [Ricinus communis]
          Length = 974

 Score =  394 bits (1013), Expect = e-120
 Identities = 221/480 (46%), Positives = 296/480 (61%), Gaps = 10/480 (2%)
 Frame = +2

Query: 752  GKPSAVSFSAE--PEIFVNKEIPIRATSNYIEQPTMSSLNG--KGPLKVQPSSGIEIDER 919
            GK S++  S E  PEI++++ I + AT    +Q   S +N   K   K QP+S  +   +
Sbjct: 507  GKTSSLENSREEKPEIYMSRSISLEATVRQSQQNIFSIVNDEKKSGKKTQPNSSCQ--NQ 564

Query: 920  KSSNVFKGRLFRFSPSFPAARRGEIIQWINEGGGQIFGDCIDIDSDFTVECHGVVPSDAG 1099
            K   VFKG++F FS SFPA RR EII+W+++GGG++  D    + +FT+ECHG +P   G
Sbjct: 565  KPLTVFKGKIFCFSNSFPADRRAEIIEWVSQGGGKMVEDHTKKNVNFTIECHGTIPRCMG 624

Query: 1100 ---SVYVSSHWVKSSLEDGRLLDVGSHILYSPLPCQIPFVSLEKFKICISQYNEKERSLL 1270
               + YVSSHWV+S LED  LLDVG HI+YSPLPCQIP    E F+ CISQY EK+R LL
Sbjct: 625  GSQTTYVSSHWVRSCLEDESLLDVGGHIIYSPLPCQIPLPGFENFRFCISQYEEKDRLLL 684

Query: 1271 KNLCFVLGTKFTEKLTKSVTHLLCKFASGPKYEASCKWGMQSVTAEWLYECIKQNKVIDP 1450
            +NLCFVLG KF EKLT+ VTHLLCKF +GPKYEA+CKWG+ S+T+EW+YEC++QN+V+  
Sbjct: 685  RNLCFVLGAKFVEKLTRKVTHLLCKFTNGPKYEAACKWGICSITSEWIYECVRQNEVVAL 744

Query: 1451 DPFHPKQATSQEREAGLCTMSQYPTQAFQMTSGDNASQLPIQSEELKNVQNESHPRKVVG 1630
            D F PK+ TSQ++EAGLCT+SQ+PTQA +M SG+N SQL  QS +L++   ++    +  
Sbjct: 745  DRFRPKEVTSQDQEAGLCTVSQFPTQAARMISGENPSQLISQSRDLRSAPTQTGSIGIFS 804

Query: 1631 FEETVPPSSCRKREASIAENPTSMLSSVSKQFDHGLTVLSTKNMEESAKVVSEFH---DD 1801
            F E    S+   ++A + ++     + +S   D  +  +++    +S       H   D 
Sbjct: 805  FGEDAQKSTKYSKKARLLKS-DDQEAQLSFHLDDPVYTINSTRGNDSKDTAGSSHGVPDV 863

Query: 1802 VAAIEDLLEQTSTISDHMSTEISLFPFDGSLRGQASDCTIRDQATDFSIRGLDDVDPSSY 1981
             AAIEDLLEQTS I D  S                S+C      +D  I G D     S 
Sbjct: 864  AAAIEDLLEQTSKIHDQKSL-------------GKSECDKNLYPSD-PILGEDHGGSHSV 909

Query: 1982 TKVQMDCINRPARNFDKINLPRTVATEAYDNFSETQTDSQIVGYAEDLSGRQMIIDRVRS 2161
              V    +NR  +  D  N  R V    YDNF+ETQT+SQ+V Y EDLSGRQMIIDRVR+
Sbjct: 910  IGVPNHWLNRTGKRDDLSNPSREVNRGVYDNFTETQTESQVVLYEEDLSGRQMIIDRVRT 969



 Score =  237 bits (605), Expect = 2e-62
 Identities = 133/242 (54%), Positives = 167/242 (69%), Gaps = 5/242 (2%)
 Frame = +1

Query: 1   APEGDKYVVAKQWGHILIVTRKWFDQSLSRRVCLNEESYPVQSTPASSLSISRKKARHSQ 180
           APEGDKY VA++WGHI IV RKWFDQS++RR CLNEESYPVQ   ASS+  S   A+H  
Sbjct: 231 APEGDKYKVAQRWGHIHIVMRKWFDQSVARRACLNEESYPVQGGSASSIKKSSSMAQHII 290

Query: 181 ETSSGISQCAKPSAGMASSS--ELCGPTISQ-DPEVTVSHNIFTVVSE--VSMFNNDGEX 345
             S  +     PSA  A S+   L G  +S  D E T+S N+ ++ S+  VS+   D E 
Sbjct: 291 GNSISV-----PSAAPAESNLPGLPGAGVSDLDLEPTLSQNMSSMFSDPPVSVKEWDNEV 345

Query: 346 XXXXXXXXXXXXNASEPNVDIPLNNCIANDSQTEDNDLYLSECRITIVGFEASELRKLVS 525
                        A  P  +  L+ C+ANDSQ+ED+DLYLSECRI++VGFEASELRKLV+
Sbjct: 346 P------------AVHPTNETNLDGCVANDSQSEDSDLYLSECRISLVGFEASELRKLVN 393

Query: 526 IVRRGGGSRYMHFNEKLTHIVVGSPSEIEIRETRTLASRGIIHVVKKEWLEDCDREKKEF 705
           +VRRGGGSRY+ FN+KLTHIVVG+P+E+E +E R LA+ G+I VV+  WLEDCDR+KKE 
Sbjct: 394 MVRRGGGSRYLSFNDKLTHIVVGAPTEVEKKELRGLAALGVIDVVRPTWLEDCDRQKKEV 453

Query: 706 PV 711
           PV
Sbjct: 454 PV 455


>XP_010664171.1 PREDICTED: DNA topoisomerase 2-binding protein 1-A isoform X2 [Vitis
            vinifera]
          Length = 948

 Score =  394 bits (1011), Expect = e-120
 Identities = 225/476 (47%), Positives = 286/476 (60%), Gaps = 17/476 (3%)
 Frame = +2

Query: 785  PEIFVNKEIPIRATSNYIEQPTMSSLNGKGPLKVQP----SSGIEIDERKSSNVFKGRLF 952
            PE+ VN +  +  T+   +Q +M S+N K     Q     S+ + + + K S VFKG+ F
Sbjct: 487  PEVNVNWDNFLEETARSAQQ-SMPSINDKYKKTQQKMEQYSNTLNVKDGKESRVFKGKQF 545

Query: 953  RFSPSFPAARRGEIIQWINEGGGQIFGDCIDIDSDFTVECHG-VVPSDAGS---VYVSSH 1120
            RFS SFP  RR EI+QW+N+GGG +  D    +  F VECHG ++P    +    +VSSH
Sbjct: 546  RFSHSFPEDRRAEIVQWVNQGGGDVVDDWCKQNVHFVVECHGALLPKSVNASQTTHVSSH 605

Query: 1121 WVKSSLEDGRLLDVGSHILYSPLPCQIPFVSLEKFKICISQYNEKERSLLKNLCFVLGTK 1300
            W++S LEDG LLDV SHILYSPLPCQIP    EK + C+SQY EK+R LL+NLCFVLG K
Sbjct: 606  WIRSCLEDGCLLDVSSHILYSPLPCQIPLPGFEKLRFCVSQYEEKDRLLLRNLCFVLGAK 665

Query: 1301 FTEKLTKSVTHLLCKFASGPKYEASCKWGMQSVTAEWLYECIKQNKVIDPDPFHPKQATS 1480
            F EKLTK VTHLLCKF  GPKYEA+CKWG+++VT+EW+YECIKQN V+  D F PK+ T+
Sbjct: 666  FVEKLTKKVTHLLCKFTGGPKYEAACKWGIKAVTSEWIYECIKQNGVVYVDSFCPKEITA 725

Query: 1481 QEREAGLCTMSQYPTQAFQMTSGDNASQLPIQSEELKNVQNESHPRKVVGFEETVPPSSC 1660
             +R+AGLC MSQYPTQA QM S D  SQLP QS +L ++  +S   +   F E    SS 
Sbjct: 726  HDRQAGLCIMSQYPTQAAQMISADKGSQLPTQSHDLGDIPTQSICNRSDRFNEEARHSSV 785

Query: 1661 RKREASIAENPTSM---------LSSVSKQFDHGLTVLSTKNMEESAKVVSEFHDDVAAI 1813
              + A + E+ +           +  +SK    G T+  T   EE++ VV    D  AAI
Sbjct: 786  HAKRARLLEDESQKTVPPSGAQDMDFISKMNSSGTTI--TAVTEETSHVVP---DVAAAI 840

Query: 1814 EDLLEQTSTISDHMSTEISLFPFDGSLRGQASDCTIRDQATDFSIRGLDDVDPSSYTKVQ 1993
            EDLLEQTS I D  S                + C     ++D S  G D  D  S   + 
Sbjct: 841  EDLLEQTSKIHDLKSP-------------GRTGCEKHLFSSDCSPLGQDHADSHSSFDLS 887

Query: 1994 MDCINRPARNFDKINLPRTVATEAYDNFSETQTDSQIVGYAEDLSGRQMIIDRVRS 2161
               +NR  +  D  N P  V    YD FSETQT+SQ+VGY EDLSGRQMIIDRVR+
Sbjct: 888  KHWLNRIEKKDDICNPPGDVKASTYDGFSETQTESQVVGYEEDLSGRQMIIDRVRT 943



 Score =  189 bits (479), Expect = 4e-46
 Identities = 108/240 (45%), Positives = 140/240 (58%), Gaps = 3/240 (1%)
 Frame = +1

Query: 1   APEGDKYVVAKQWGHILIVTRKWFDQSLSRR--VCLNEESYP-VQSTPASSLSISRKKAR 171
           APEGDKY VA++WGHI IVTRKWFDQS++R+   C+  + Y  +Q+ P S +        
Sbjct: 231 APEGDKYKVARRWGHIHIVTRKWFDQSIARKGWYCIFNQLYSNLQAVPCSGIG------- 283

Query: 172 HSQETSSGISQCAKPSAGMASSSELCGPTISQDPEVTVSHNIFTVVSEVSMFNNDGEXXX 351
                                           D E T+S N  +   +  +F  +GE   
Sbjct: 284 ------------------------------DPDLEATLSQNTCSTFLDAPIFIKEGETRE 313

Query: 352 XXXXXXXXXXNASEPNVDIPLNNCIANDSQTEDNDLYLSECRITIVGFEASELRKLVSIV 531
                      A +   +  L+  +A+DSQTED+DLYLS+CRI +VGFEASE+RKLV++V
Sbjct: 314 P----------AMQDKDENKLDGLVADDSQTEDSDLYLSDCRILLVGFEASEMRKLVNMV 363

Query: 532 RRGGGSRYMHFNEKLTHIVVGSPSEIEIRETRTLASRGIIHVVKKEWLEDCDREKKEFPV 711
           RRGGGSRYM FNEKLTHIVVG+PSE+E +  R LA+ G+I VV+  WLEDCD EKKE  V
Sbjct: 364 RRGGGSRYMSFNEKLTHIVVGTPSEVEKKVVRGLAATGVISVVRTIWLEDCDHEKKEVSV 423


>CBI18968.3 unnamed protein product, partial [Vitis vinifera]
          Length = 952

 Score =  394 bits (1011), Expect = e-120
 Identities = 225/476 (47%), Positives = 286/476 (60%), Gaps = 17/476 (3%)
 Frame = +2

Query: 785  PEIFVNKEIPIRATSNYIEQPTMSSLNGKGPLKVQP----SSGIEIDERKSSNVFKGRLF 952
            PE+ VN +  +  T+   +Q +M S+N K     Q     S+ + + + K S VFKG+ F
Sbjct: 491  PEVNVNWDNFLEETARSAQQ-SMPSINDKYKKTQQKMEQYSNTLNVKDGKESRVFKGKQF 549

Query: 953  RFSPSFPAARRGEIIQWINEGGGQIFGDCIDIDSDFTVECHG-VVPSDAGS---VYVSSH 1120
            RFS SFP  RR EI+QW+N+GGG +  D    +  F VECHG ++P    +    +VSSH
Sbjct: 550  RFSHSFPEDRRAEIVQWVNQGGGDVVDDWCKQNVHFVVECHGALLPKSVNASQTTHVSSH 609

Query: 1121 WVKSSLEDGRLLDVGSHILYSPLPCQIPFVSLEKFKICISQYNEKERSLLKNLCFVLGTK 1300
            W++S LEDG LLDV SHILYSPLPCQIP    EK + C+SQY EK+R LL+NLCFVLG K
Sbjct: 610  WIRSCLEDGCLLDVSSHILYSPLPCQIPLPGFEKLRFCVSQYEEKDRLLLRNLCFVLGAK 669

Query: 1301 FTEKLTKSVTHLLCKFASGPKYEASCKWGMQSVTAEWLYECIKQNKVIDPDPFHPKQATS 1480
            F EKLTK VTHLLCKF  GPKYEA+CKWG+++VT+EW+YECIKQN V+  D F PK+ T+
Sbjct: 670  FVEKLTKKVTHLLCKFTGGPKYEAACKWGIKAVTSEWIYECIKQNGVVYVDSFCPKEITA 729

Query: 1481 QEREAGLCTMSQYPTQAFQMTSGDNASQLPIQSEELKNVQNESHPRKVVGFEETVPPSSC 1660
             +R+AGLC MSQYPTQA QM S D  SQLP QS +L ++  +S   +   F E    SS 
Sbjct: 730  HDRQAGLCIMSQYPTQAAQMISADKGSQLPTQSHDLGDIPTQSICNRSDRFNEEARHSSV 789

Query: 1661 RKREASIAENPTSM---------LSSVSKQFDHGLTVLSTKNMEESAKVVSEFHDDVAAI 1813
              + A + E+ +           +  +SK    G T+  T   EE++ VV    D  AAI
Sbjct: 790  HAKRARLLEDESQKTVPPSGAQDMDFISKMNSSGTTI--TAVTEETSHVVP---DVAAAI 844

Query: 1814 EDLLEQTSTISDHMSTEISLFPFDGSLRGQASDCTIRDQATDFSIRGLDDVDPSSYTKVQ 1993
            EDLLEQTS I D  S                + C     ++D S  G D  D  S   + 
Sbjct: 845  EDLLEQTSKIHDLKSP-------------GRTGCEKHLFSSDCSPLGQDHADSHSSFDLS 891

Query: 1994 MDCINRPARNFDKINLPRTVATEAYDNFSETQTDSQIVGYAEDLSGRQMIIDRVRS 2161
               +NR  +  D  N P  V    YD FSETQT+SQ+VGY EDLSGRQMIIDRVR+
Sbjct: 892  KHWLNRIEKKDDICNPPGDVKASTYDGFSETQTESQVVGYEEDLSGRQMIIDRVRT 947



 Score =  207 bits (527), Expect = 3e-52
 Identities = 113/237 (47%), Positives = 141/237 (59%)
 Frame = +1

Query: 1   APEGDKYVVAKQWGHILIVTRKWFDQSLSRRVCLNEESYPVQSTPASSLSISRKKARHSQ 180
           +PEGDKY VA++WGHI IVTRKWFDQS++R+ C+NEESY VQ   ASS++  R     SQ
Sbjct: 234 SPEGDKYKVARRWGHIHIVTRKWFDQSIARKACVNEESYTVQGGTASSINSVRTHLTASQ 293

Query: 181 ETSSGISQCAKPSAGMASSSELCGPTISQDPEVTVSHNIFTVVSEVSMFNNDGEXXXXXX 360
                       S+ +A+ S L  P +    E                            
Sbjct: 294 SQDKSNVNFQSASSSLAADSNLQAPAMQDKDENK-------------------------- 327

Query: 361 XXXXXXXNASEPNVDIPLNNCIANDSQTEDNDLYLSECRITIVGFEASELRKLVSIVRRG 540
                            L+  +A+DSQTED+DLYLS+CRI +VGFEASE+RKLV++VRRG
Sbjct: 328 -----------------LDGLVADDSQTEDSDLYLSDCRILLVGFEASEMRKLVNMVRRG 370

Query: 541 GGSRYMHFNEKLTHIVVGSPSEIEIRETRTLASRGIIHVVKKEWLEDCDREKKEFPV 711
           GGSRYM FNEKLTHIVVG+PSE+E +  R LA+ G+I VV+  WLEDCD EKKE  V
Sbjct: 371 GGSRYMSFNEKLTHIVVGTPSEVEKKVVRGLAATGVISVVRTIWLEDCDHEKKEVSV 427


>XP_010664170.1 PREDICTED: DNA topoisomerase 2-binding protein 1-A isoform X1 [Vitis
            vinifera]
          Length = 986

 Score =  394 bits (1011), Expect = e-119
 Identities = 225/476 (47%), Positives = 286/476 (60%), Gaps = 17/476 (3%)
 Frame = +2

Query: 785  PEIFVNKEIPIRATSNYIEQPTMSSLNGKGPLKVQP----SSGIEIDERKSSNVFKGRLF 952
            PE+ VN +  +  T+   +Q +M S+N K     Q     S+ + + + K S VFKG+ F
Sbjct: 525  PEVNVNWDNFLEETARSAQQ-SMPSINDKYKKTQQKMEQYSNTLNVKDGKESRVFKGKQF 583

Query: 953  RFSPSFPAARRGEIIQWINEGGGQIFGDCIDIDSDFTVECHG-VVPSDAGS---VYVSSH 1120
            RFS SFP  RR EI+QW+N+GGG +  D    +  F VECHG ++P    +    +VSSH
Sbjct: 584  RFSHSFPEDRRAEIVQWVNQGGGDVVDDWCKQNVHFVVECHGALLPKSVNASQTTHVSSH 643

Query: 1121 WVKSSLEDGRLLDVGSHILYSPLPCQIPFVSLEKFKICISQYNEKERSLLKNLCFVLGTK 1300
            W++S LEDG LLDV SHILYSPLPCQIP    EK + C+SQY EK+R LL+NLCFVLG K
Sbjct: 644  WIRSCLEDGCLLDVSSHILYSPLPCQIPLPGFEKLRFCVSQYEEKDRLLLRNLCFVLGAK 703

Query: 1301 FTEKLTKSVTHLLCKFASGPKYEASCKWGMQSVTAEWLYECIKQNKVIDPDPFHPKQATS 1480
            F EKLTK VTHLLCKF  GPKYEA+CKWG+++VT+EW+YECIKQN V+  D F PK+ T+
Sbjct: 704  FVEKLTKKVTHLLCKFTGGPKYEAACKWGIKAVTSEWIYECIKQNGVVYVDSFCPKEITA 763

Query: 1481 QEREAGLCTMSQYPTQAFQMTSGDNASQLPIQSEELKNVQNESHPRKVVGFEETVPPSSC 1660
             +R+AGLC MSQYPTQA QM S D  SQLP QS +L ++  +S   +   F E    SS 
Sbjct: 764  HDRQAGLCIMSQYPTQAAQMISADKGSQLPTQSHDLGDIPTQSICNRSDRFNEEARHSSV 823

Query: 1661 RKREASIAENPTSM---------LSSVSKQFDHGLTVLSTKNMEESAKVVSEFHDDVAAI 1813
              + A + E+ +           +  +SK    G T+  T   EE++ VV    D  AAI
Sbjct: 824  HAKRARLLEDESQKTVPPSGAQDMDFISKMNSSGTTI--TAVTEETSHVVP---DVAAAI 878

Query: 1814 EDLLEQTSTISDHMSTEISLFPFDGSLRGQASDCTIRDQATDFSIRGLDDVDPSSYTKVQ 1993
            EDLLEQTS I D  S                + C     ++D S  G D  D  S   + 
Sbjct: 879  EDLLEQTSKIHDLKSP-------------GRTGCEKHLFSSDCSPLGQDHADSHSSFDLS 925

Query: 1994 MDCINRPARNFDKINLPRTVATEAYDNFSETQTDSQIVGYAEDLSGRQMIIDRVRS 2161
               +NR  +  D  N P  V    YD FSETQT+SQ+VGY EDLSGRQMIIDRVR+
Sbjct: 926  KHWLNRIEKKDDICNPPGDVKASTYDGFSETQTESQVVGYEEDLSGRQMIIDRVRT 981



 Score =  226 bits (577), Expect = 9e-59
 Identities = 122/241 (50%), Positives = 155/241 (64%), Gaps = 4/241 (1%)
 Frame = +1

Query: 1   APEGDKYVVAKQWGHILIVTRKWFDQSLSRRVCLNEESYPVQSTPASSLSISRKKARHSQ 180
           APEGDKY VA++WGHI IVTRKWFDQS++R+ C+NEESY VQ   ASS++  R     SQ
Sbjct: 231 APEGDKYKVARRWGHIHIVTRKWFDQSIARKACVNEESYTVQGGTASSINSVRTHLTASQ 290

Query: 181 ETSSGISQCAKPSAGMASSSEL----CGPTISQDPEVTVSHNIFTVVSEVSMFNNDGEXX 348
                       S+ +A+ S L    C      D E T+S N  +   +  +F  +GE  
Sbjct: 291 SQDKSNVNFQSASSSLAADSNLQAVPCSGIGDPDLEATLSQNTCSTFLDAPIFIKEGETR 350

Query: 349 XXXXXXXXXXXNASEPNVDIPLNNCIANDSQTEDNDLYLSECRITIVGFEASELRKLVSI 528
                       A +   +  L+  +A+DSQTED+DLYLS+CRI +VGFEASE+RKLV++
Sbjct: 351 EP----------AMQDKDENKLDGLVADDSQTEDSDLYLSDCRILLVGFEASEMRKLVNM 400

Query: 529 VRRGGGSRYMHFNEKLTHIVVGSPSEIEIRETRTLASRGIIHVVKKEWLEDCDREKKEFP 708
           VRRGGGSRYM FNEKLTHIVVG+PSE+E +  R LA+ G+I VV+  WLEDCD EKKE  
Sbjct: 401 VRRGGGSRYMSFNEKLTHIVVGTPSEVEKKVVRGLAATGVISVVRTIWLEDCDHEKKEVS 460

Query: 709 V 711
           V
Sbjct: 461 V 461


>XP_019246538.1 PREDICTED: DNA topoisomerase 2-binding protein 1 [Nicotiana
            attenuata]
          Length = 990

 Score =  390 bits (1003), Expect = e-118
 Identities = 214/433 (49%), Positives = 272/433 (62%), Gaps = 6/433 (1%)
 Frame = +2

Query: 881  KVQPSSGIEIDERKSSNVFKGRLFRFSPSFPAARRGEIIQWINEGGGQIFGDCIDIDSDF 1060
            K+   SG  ++ RK S+VF+GR F FS SFP  RR EI++W+++GGG +  D  + +  F
Sbjct: 565  KLLNESGCAVNGRKPSSVFEGRRFCFSASFPVDRRAEIVEWVSQGGGVVVEDQTETNVHF 624

Query: 1061 TVECHGVVPSD---AGSVYVSSHWVKSSLEDGRLLDVGSHILYSPLPCQIPFVSLEKFKI 1231
            TVECHG + S+   A + +VSSHW+KS LEDG LLDVGSHILYSPLPC++PF + + F  
Sbjct: 625  TVECHGTLRSEKDGAAATFVSSHWIKSCLEDGCLLDVGSHILYSPLPCRVPFPAFQSFHF 684

Query: 1232 CISQYNEKERSLLKNLCFVLGTKFTEKLTKSVTHLLCKFASGPKYEASCKWGMQSVTAEW 1411
            C+SQY+EKER LL+NLCF +G KF EKLTK VTHLLCKF SGPKYE +CKWG+Q VT EW
Sbjct: 685  CVSQYDEKERQLLRNLCFTIGAKFAEKLTKRVTHLLCKFISGPKYEVACKWGIQPVTCEW 744

Query: 1412 LYECIKQNKVIDPDPFHPKQATSQEREAGLCTMSQYPTQAFQMTSGDNASQLPIQSEELK 1591
            +YECIK NK++ PDPF+PK+ TS++REAG+CT SQ+PTQA +M SGD +SQ   Q +EL 
Sbjct: 745  IYECIKLNKIVSPDPFYPKEVTSEDREAGVCTTSQFPTQAVRMISGDTSSQPQSQPQELI 804

Query: 1592 NVQNESHPRKVVGFEETVPPSSCRKR-EASIAENPTSMLSSVSKQFDHGL-TVLSTKNME 1765
            N++ E+   + +  EE    S   K+    + E     L+ VS + +    T    KNM 
Sbjct: 805  NLRTEAFAGRSIAKEEMKHSSRWNKKARLLVVEETNCSLTCVSNENNAFCGTNPPEKNMI 864

Query: 1766 ESAKVVSEFHDDV-AAIEDLLEQTSTISDHMSTEISLFPFDGSLRGQASDCTIRDQATDF 1942
             S K  S    DV AAIEDLLEQTS I D  S   S    D  L     +   +      
Sbjct: 865  GSTKEGSSAVPDVAAAIEDLLEQTSKIHDQKSP--SRIECDKELFTSGCNTLAQGHGDHH 922

Query: 1943 SIRGLDDVDPSSYTKVQMDCINRPARNFDKINLPRTVATEAYDNFSETQTDSQIVGYAED 2122
            +  GL +           D   R  +  D            YD+FSETQTDSQ+VGYAED
Sbjct: 923  TTLGLSN-----------DWTTRFEKKDDSHGHSGDATANVYDHFSETQTDSQVVGYAED 971

Query: 2123 LSGRQMIIDRVRS 2161
            LSGRQMIIDRVR+
Sbjct: 972  LSGRQMIIDRVRT 984



 Score =  214 bits (545), Expect = 1e-54
 Identities = 115/247 (46%), Positives = 155/247 (62%), Gaps = 10/247 (4%)
 Frame = +1

Query: 1   APEGDKYVVAKQWGHILIVTRKWFDQSLSRRVCLNEESYPVQSTPASSLSISRKKARHSQ 180
           APEG+KY VAK+WGHI  VT++WFDQS++RR CL+EESYPVQ+   ++++  R   +HS 
Sbjct: 231 APEGEKYKVAKRWGHIHTVTKRWFDQSVARRACLDEESYPVQAGSPNTMTTLRMTNQHSL 290

Query: 181 ETS----SGISQCAKPSAGMASSSELCGPTISQDPEVTVSHNIFTVVSEVSMFNNDGEXX 348
           +       G+S  A PS    +   LC        E T+S ++           N     
Sbjct: 291 KKGMRNLQGLSSLATPSN---AEPVLCSGASDSYVEATLSQDMSDAPVLTKEEENLAPAE 347

Query: 349 XXXXXXXXXXXNASEPN---VDIPLNNC---IANDSQTEDNDLYLSECRITIVGFEASEL 510
                        +E +   ++   N+C   +A+DSQT+DND YL++CRI IVGF ASE+
Sbjct: 348 NPKSDYSAPVSTKNEQSGAPIEQEKNDCDGGVADDSQTDDNDFYLADCRILIVGFNASEM 407

Query: 511 RKLVSIVRRGGGSRYMHFNEKLTHIVVGSPSEIEIRETRTLASRGIIHVVKKEWLEDCDR 690
           RKLV++VR+GGGSRYM F EKLTHI+ G+PSE EI+E R LA+ G++HVVK  WL+DCDR
Sbjct: 408 RKLVNLVRKGGGSRYMSFGEKLTHIIAGNPSENEIKELRNLAALGVVHVVKSGWLQDCDR 467

Query: 691 EKKEFPV 711
           EKKE PV
Sbjct: 468 EKKEVPV 474


>XP_016472763.1 PREDICTED: DNA topoisomerase 2-binding protein 1 [Nicotiana tabacum]
          Length = 990

 Score =  390 bits (1001), Expect = e-118
 Identities = 213/433 (49%), Positives = 276/433 (63%), Gaps = 6/433 (1%)
 Frame = +2

Query: 881  KVQPSSGIEIDERKSSNVFKGRLFRFSPSFPAARRGEIIQWINEGGGQIFGDCIDIDSDF 1060
            K+   SG  ++ RK S+VF+GR F FS SFP  RR EI++W+++GGG +  D  + +  F
Sbjct: 565  KLVNESGCAVNGRKPSSVFEGRRFCFSASFPVDRRTEIVEWVSQGGGVVVEDQTETNVHF 624

Query: 1061 TVECHGVVPSD---AGSVYVSSHWVKSSLEDGRLLDVGSHILYSPLPCQIPFVSLEKFKI 1231
            TVECHG++ S+   A + +VSSHW+KS LEDG LLDVGSHILYSPLPC++PF + + F++
Sbjct: 625  TVECHGMLRSEKDGAVATFVSSHWIKSCLEDGCLLDVGSHILYSPLPCRVPFPAFQSFRL 684

Query: 1232 CISQYNEKERSLLKNLCFVLGTKFTEKLTKSVTHLLCKFASGPKYEASCKWGMQSVTAEW 1411
            C+SQY+EKE+ LL+NLCF +G KF EKLTK VTHLLCKF SGPKYEA+CKWG+Q VT EW
Sbjct: 685  CVSQYDEKEKQLLRNLCFTIGAKFVEKLTKRVTHLLCKFTSGPKYEAACKWGIQPVTCEW 744

Query: 1412 LYECIKQNKVIDPDPFHPKQATSQEREAGLCTMSQYPTQAFQMTSGDNASQLPIQSEELK 1591
            +YECIKQNK++ PD F+PK+ T+++REAG+CTMSQ+PTQA +M S D +SQ   Q +EL 
Sbjct: 745  IYECIKQNKIVSPDQFYPKEVTAEDREAGVCTMSQFPTQAVRMISSDTSSQPQSQPQELI 804

Query: 1592 NVQNESHPRKVVGFEETVPPSSCRKR-EASIAENPTSMLSSVSKQFDHGL-TVLSTKNME 1765
            N++ E+   + +  EE    S   K+    + E     L+ VS + +    T    KNM 
Sbjct: 805  NLRTEAFAGRSIAKEEMKHSSRWNKKARLLVVEETNCSLTCVSNENNAFCGTNPPEKNMI 864

Query: 1766 ESAKVVSEFHDDV-AAIEDLLEQTSTISDHMSTEISLFPFDGSLRGQASDCTIRDQATDF 1942
             S K  S    DV AAIEDLLEQTS I D  S   S    D  L     +   +      
Sbjct: 865  GSTKEDSSAVPDVAAAIEDLLEQTSKIHDQKSP--SRIECDKELFTSGCNTLAQGHGDHH 922

Query: 1943 SIRGLDDVDPSSYTKVQMDCINRPARNFDKINLPRTVATEAYDNFSETQTDSQIVGYAED 2122
            +  GL +              NR  +  D            YD+FSETQTDSQ+VGYAED
Sbjct: 923  ATLGLSN-----------HWTNRFEKKDDSHGHSGDATANVYDHFSETQTDSQVVGYAED 971

Query: 2123 LSGRQMIIDRVRS 2161
            LSGRQMIIDRVR+
Sbjct: 972  LSGRQMIIDRVRT 984



 Score =  215 bits (547), Expect = 8e-55
 Identities = 116/248 (46%), Positives = 156/248 (62%), Gaps = 11/248 (4%)
 Frame = +1

Query: 1   APEGDKYVVAKQWGHILIVTRKWFDQSLSRRVCLNEESYPVQSTPASSLSISRKKARHSQ 180
           APEG+KY VAK+WGHI  VT++WFDQS++RR CL+EESYPVQ+   ++++  R   +HS 
Sbjct: 231 APEGEKYKVAKRWGHIHTVTKRWFDQSVARRACLDEESYPVQAGSPNTMTTLRMPNQHSL 290

Query: 181 ETS----SGISQCAKPSAGMASSSELCGPTISQDPEVTVSHNI----FTVVSEVSMFNND 336
           E       G+S  A PS    +   LC        E T+S ++         E ++   +
Sbjct: 291 EKGMRNLQGLSSLATPSN---AEPVLCSGATDSYVEATLSQDMPDAPVLTKEEENLAPAE 347

Query: 337 GEXXXXXXXXXXXXXNASEPNVDIPLNNC---IANDSQTEDNDLYLSECRITIVGFEASE 507
                           +  P ++   N+C   +A+DSQT+DND YL++CRI IVGF ASE
Sbjct: 348 NPKSDYSAPVSTKDEQSGAP-IEQEKNDCDGGVADDSQTDDNDFYLADCRILIVGFNASE 406

Query: 508 LRKLVSIVRRGGGSRYMHFNEKLTHIVVGSPSEIEIRETRTLASRGIIHVVKKEWLEDCD 687
           +RKLV++VR+GGGSRYM F EKLTHI+ G+PSE EI+E R LA+ G+IHVVK  WL+DCD
Sbjct: 407 MRKLVNLVRKGGGSRYMSFGEKLTHIIAGNPSEFEIKELRNLAALGVIHVVKSGWLQDCD 466

Query: 688 REKKEFPV 711
            EKKE PV
Sbjct: 467 LEKKEVPV 474