BLASTX 2.2.25 [Feb-01-2011]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= Lithospermum22_contig00018548
         (2055 letters)

Database: ./nr 
           23,641,837 sequences; 8,123,359,852 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gb|ACD37361.1| 3-hydroxy-3-methylglutaryl-coenzyme A reductase [...   705   0.0  
gb|ABC74565.1| 3-hydroxy-3-methylglutaryl-CoA reductase [Picrorh...   701   0.0  
gb|AAV54051.1| 3-hydroxy-3-methylglutaryl coenzyme A reductase [...   689   0.0  
gb|AFN89600.1| 3-hydro-3-methylglutary CoA reductase [Gentiana m...   689   0.0  
gb|AAD03789.1| 3-hydroxy-3-methylglutaryl-coenzyme A reductase [...   684   0.0  

>gb|ACD37361.1| 3-hydroxy-3-methylglutaryl-coenzyme A reductase [Salvia miltiorrhiza]
          Length = 565

 Score =  705 bits (1819), Expect(2) = 0.0
 Identities = 356/469 (75%), Positives = 404/469 (86%), Gaps = 9/469 (1%)
 Frame = -3

Query: 1687 FFGIDFVQSFVVDSPPRERRRRL----DKSV-----PSKPILRMSQGSVVALNCEEEEEL 1535
            FFGIDFVQSF+      E  +R     D+ +     P  P++  ++ +V     +++EE+
Sbjct: 97   FFGIDFVQSFISKPESDEDHQRFILHEDRKIHCGLPPPAPVVAKAKAAVELP--QDDEEV 154

Query: 1534 VKDVVSGQIPSYSLEARIGDCYKAAFVRREAVQRLTGKSLEGLPLAGFDYDSILGQCCEM 1355
            V  VVSG+IPSYSLE+R+GDC +AA +RREAVQRLTG+ ++GLPL GFDYDSILGQCCEM
Sbjct: 155  VDRVVSGEIPSYSLESRLGDCLRAAKIRREAVQRLTGRGVDGLPLEGFDYDSILGQCCEM 214

Query: 1354 PVGYVQIPVGVVGPLLLNGCEYTVPMATTEGCLVASTNRGCKAIYASGGATCVLLRDAMT 1175
            PVGYVQIPVG+ GPLLLNGCEY+VPMATTEGCLVASTNRGCKAIYASGGATCVLLRDAMT
Sbjct: 215  PVGYVQIPVGIAGPLLLNGCEYSVPMATTEGCLVASTNRGCKAIYASGGATCVLLRDAMT 274

Query: 1174 RAPVVRFSTAKRASELKFFLEDPLNFDTLAVVFNKSSRFGRLQSIQCSIAGKNLYIRFSC 995
            RAPVVRFS+AKRA+ELKFFLEDPLNFDTL+VVFNKSSRF RLQ++QC+IAGKNLYIRFSC
Sbjct: 275  RAPVVRFSSAKRATELKFFLEDPLNFDTLSVVFNKSSRFARLQNVQCAIAGKNLYIRFSC 334

Query: 994  STGDAMGMNMVSKGVQNVLDYLQTDFPDMDVIGISGNFCSDKKPAAVNWIEGRGKSVVCE 815
            STGDAMGMNMVSKGVQNVLD+LQ DFPDMDVIGISGN+CSDKKP+AVNWIEGRGKSVVCE
Sbjct: 335  STGDAMGMNMVSKGVQNVLDFLQNDFPDMDVIGISGNYCSDKKPSAVNWIEGRGKSVVCE 394

Query: 814  AIISEEXXXXXXXXXXXXXXXLNMLKNXXXXXXXXXXXGFNAHASNIVSAIFLATGQDPA 635
            A+I+ +               LNMLKN           GFNAHA+NIVSAIF+ATGQDPA
Sbjct: 395  AVITADVVSKVLKTTVPSLVELNMLKNLTGSAIAGALGGFNAHAANIVSAIFIATGQDPA 454

Query: 634  QNVESSHCITMMEAVNDGKDLHVSVTMPSIEVGTIGGGTQLASQSACLNLLGVKGANKES 455
            QN+ESSHCITMMEA+NDGKDLH+SVTMPSIEVGT+GGGTQLASQSACLNLLGVKGANKES
Sbjct: 455  QNIESSHCITMMEAINDGKDLHISVTMPSIEVGTVGGGTQLASQSACLNLLGVKGANKES 514

Query: 454  PGTNSRLLATIVAGSVLAGELSLMSAISAGQLVKSHMKYNRSSKDVSQI 308
            PG+N+RLLATIVAG+VLAGELSLMSAISAGQLVKSHMKYNRSS+D+++I
Sbjct: 515  PGSNARLLATIVAGAVLAGELSLMSAISAGQLVKSHMKYNRSSRDITKI 563



 Score = 95.9 bits (237), Expect(2) = 0.0
 Identities = 46/55 (83%), Positives = 50/55 (90%)
 Frame = -2

Query: 1853 YLTNTIFFTLFFSVAYFLLIRWREKIHNSTPLHVLTFSELAGLVSLIASFIYLLG 1689
            YLTN IFFTLFFSVAYFLL RWR+KI NSTPLH+LT SELAG++ LIASFIYLLG
Sbjct: 42   YLTNGIFFTLFFSVAYFLLHRWRDKIRNSTPLHILTLSELAGILCLIASFIYLLG 96


>gb|ABC74565.1| 3-hydroxy-3-methylglutaryl-CoA reductase [Picrorhiza kurrooa]
          Length = 561

 Score =  701 bits (1810), Expect(2) = 0.0
 Identities = 357/463 (77%), Positives = 400/463 (86%), Gaps = 2/463 (0%)
 Frame = -3

Query: 1687 FFGIDFVQSFVVDSPPRERR-RRLDKSVPSKPILRMSQGSVVALNC-EEEEELVKDVVSG 1514
            FFGIDFVQSF   S   +      D+S+   PI   +   +V ++  +++EE+V  VVSG
Sbjct: 101  FFGIDFVQSFTSKSENEDGFILHQDRSIHCPPI---APKPIVKMDLPQDDEEVVMSVVSG 157

Query: 1513 QIPSYSLEARIGDCYKAAFVRREAVQRLTGKSLEGLPLAGFDYDSILGQCCEMPVGYVQI 1334
            ++PSYSLE+R+GDC++AA +RREA+QR+TG+S+EGLPL GFDY+SILGQCCEMPVGY QI
Sbjct: 158  EVPSYSLESRLGDCFRAAKIRREALQRVTGRSVEGLPLEGFDYESILGQCCEMPVGYAQI 217

Query: 1333 PVGVVGPLLLNGCEYTVPMATTEGCLVASTNRGCKAIYASGGATCVLLRDAMTRAPVVRF 1154
            PVG+ GPLLLNGCEY+VPMATTEGCLVASTNRGCKAIYASGGATCVLLRDAMTRAPVVRF
Sbjct: 218  PVGIAGPLLLNGCEYSVPMATTEGCLVASTNRGCKAIYASGGATCVLLRDAMTRAPVVRF 277

Query: 1153 STAKRASELKFFLEDPLNFDTLAVVFNKSSRFGRLQSIQCSIAGKNLYIRFSCSTGDAMG 974
            S+ KRA++LKFFLEDPLNFDTL+VVFNKSSRF RLQSIQC IAGKNLYIRFSCSTGDAMG
Sbjct: 278  SSVKRATDLKFFLEDPLNFDTLSVVFNKSSRFARLQSIQCGIAGKNLYIRFSCSTGDAMG 337

Query: 973  MNMVSKGVQNVLDYLQTDFPDMDVIGISGNFCSDKKPAAVNWIEGRGKSVVCEAIISEEX 794
            MNMVSKGVQNVLD+LQ DFPDMDVIGISGNFCSDKKPAAVNWIEGRGKSVVCEA+IS + 
Sbjct: 338  MNMVSKGVQNVLDFLQNDFPDMDVIGISGNFCSDKKPAAVNWIEGRGKSVVCEAVISGDI 397

Query: 793  XXXXXXXXXXXXXXLNMLKNXXXXXXXXXXXGFNAHASNIVSAIFLATGQDPAQNVESSH 614
                          LNMLKN           GFNAHA+NIVSAIF+ATGQDPAQN+ESSH
Sbjct: 398  VTKVLKTNVASLVELNMLKNLAGSAIAGALGGFNAHAANIVSAIFIATGQDPAQNIESSH 457

Query: 613  CITMMEAVNDGKDLHVSVTMPSIEVGTIGGGTQLASQSACLNLLGVKGANKESPGTNSRL 434
            CITMMEAVNDGKDLHVSVTMPSIEVGT+GGGTQLASQSACLNLLGVKGA+KESPG+NS+L
Sbjct: 458  CITMMEAVNDGKDLHVSVTMPSIEVGTVGGGTQLASQSACLNLLGVKGASKESPGSNSQL 517

Query: 433  LATIVAGSVLAGELSLMSAISAGQLVKSHMKYNRSSKDVSQIA 305
            LATIVAGSVLAGELSLMSAISAGQLVKSHMKYNRSS+D++  +
Sbjct: 518  LATIVAGSVLAGELSLMSAISAGQLVKSHMKYNRSSRDITNFS 560



 Score = 92.0 bits (227), Expect(2) = 0.0
 Identities = 45/55 (81%), Positives = 48/55 (87%)
 Frame = -2

Query: 1853 YLTNTIFFTLFFSVAYFLLIRWREKIHNSTPLHVLTFSELAGLVSLIASFIYLLG 1689
            YLTN IFFTLFFSVAYFLL RWR+KI NS PLHVLT SELA ++ LIASFIYLLG
Sbjct: 46   YLTNGIFFTLFFSVAYFLLHRWRDKIRNSIPLHVLTVSELAAIICLIASFIYLLG 100


>gb|AAV54051.1| 3-hydroxy-3-methylglutaryl coenzyme A reductase [Eucommia ulmoides]
          Length = 590

 Score =  689 bits (1777), Expect(2) = 0.0
 Identities = 354/483 (73%), Positives = 399/483 (82%), Gaps = 23/483 (4%)
 Frame = -3

Query: 1687 FFGIDFVQSFV---------VDSPPR----ERRRR------LDKSV----PSKPILRMSQ 1577
            FFGIDFVQSF+         VD   R    E RRR      LD  V    PS   +R   
Sbjct: 105  FFGIDFVQSFIARASHDPWDVDDDERFILEEDRRRGPCTAALDCLVGPVAPSISDVRKLM 164

Query: 1576 GSVVALNCEEEEELVKDVVSGQIPSYSLEARIGDCYKAAFVRREAVQRLTGKSLEGLPLA 1397
                 L   E+E++VK V+SG +PSYSLE+++GDCY+AA +RREA+QR+TGKSL GLPL 
Sbjct: 165  DPPAPLPSVEDEQMVKSVISGTVPSYSLESKLGDCYRAASIRREAIQRITGKSLSGLPLE 224

Query: 1396 GFDYDSILGQCCEMPVGYVQIPVGVVGPLLLNGCEYTVPMATTEGCLVASTNRGCKAIYA 1217
            GFDY++ILGQCCEMP+G++QIPVG+ GPLLLNGCEY+VPMATTEGCLVASTNRGCKAIYA
Sbjct: 225  GFDYEAILGQCCEMPIGFLQIPVGIAGPLLLNGCEYSVPMATTEGCLVASTNRGCKAIYA 284

Query: 1216 SGGATCVLLRDAMTRAPVVRFSTAKRASELKFFLEDPLNFDTLAVVFNKSSRFGRLQSIQ 1037
            SGGAT +LLRD MTRAPVVRF +AKRASELKFFLEDPLNF+TL++VFNKSSRF RLQ IQ
Sbjct: 285  SGGATSILLRDGMTRAPVVRFPSAKRASELKFFLEDPLNFETLSMVFNKSSRFARLQGIQ 344

Query: 1036 CSIAGKNLYIRFSCSTGDAMGMNMVSKGVQNVLDYLQTDFPDMDVIGISGNFCSDKKPAA 857
            CSIAGKNLY+RF+CSTGDAMGMNMVSKGVQN+L++LQ DFPDMDVIGISGNFCSDKKPAA
Sbjct: 345  CSIAGKNLYMRFTCSTGDAMGMNMVSKGVQNILEFLQNDFPDMDVIGISGNFCSDKKPAA 404

Query: 856  VNWIEGRGKSVVCEAIISEEXXXXXXXXXXXXXXXLNMLKNXXXXXXXXXXXGFNAHASN 677
            VNWIEGRGKSVVCEAIISE+               LNMLKN           GFNAHA+N
Sbjct: 405  VNWIEGRGKSVVCEAIISEDIVRKVLKTTVPALVELNMLKNLAGSAVAGALGGFNAHAAN 464

Query: 676  IVSAIFLATGQDPAQNVESSHCITMMEAVNDGKDLHVSVTMPSIEVGTIGGGTQLASQSA 497
            IVSA+F+ATGQDPAQN+ESSHCITMMEAVNDGKDLH+SVTMPSIEVGT+GGGTQLASQSA
Sbjct: 465  IVSAVFIATGQDPAQNIESSHCITMMEAVNDGKDLHISVTMPSIEVGTVGGGTQLASQSA 524

Query: 496  CLNLLGVKGANKESPGTNSRLLATIVAGSVLAGELSLMSAISAGQLVKSHMKYNRSSKDV 317
            CLNLLGVKGANKESPG+NSRLLA IVAGSVLAGELSLMSAI+AGQLV SHMKYNRS++D 
Sbjct: 525  CLNLLGVKGANKESPGSNSRLLAAIVAGSVLAGELSLMSAIAAGQLVNSHMKYNRSNRDF 584

Query: 316  SQI 308
            +++
Sbjct: 585  TKV 587



 Score = 95.9 bits (237), Expect(2) = 0.0
 Identities = 47/55 (85%), Positives = 50/55 (90%)
 Frame = -2

Query: 1853 YLTNTIFFTLFFSVAYFLLIRWREKIHNSTPLHVLTFSELAGLVSLIASFIYLLG 1689
            YLTN IFFTLFFSVAY+LL RWR+KI NSTPLHVLT SELA +VSLIASFIYLLG
Sbjct: 50   YLTNGIFFTLFFSVAYYLLHRWRDKIRNSTPLHVLTLSELAAIVSLIASFIYLLG 104


>gb|AFN89600.1| 3-hydro-3-methylglutary CoA reductase [Gentiana macrophylla]
          Length = 580

 Score =  689 bits (1778), Expect(2) = 0.0
 Identities = 356/477 (74%), Positives = 395/477 (82%), Gaps = 16/477 (3%)
 Frame = -3

Query: 1687 FFGIDFVQSFVVDSPP----------------RERRRRLDKSVPSKPILRMSQGSVVALN 1556
            FFGIDFVQS +  + P                 ++R R     P     ++    +    
Sbjct: 105  FFGIDFVQSVITRASPDSWDVEEEEDHHHHHHHQQRFRCPPPAPISASPKLMDHHLT--- 161

Query: 1555 CEEEEELVKDVVSGQIPSYSLEARIGDCYKAAFVRREAVQRLTGKSLEGLPLAGFDYDSI 1376
             EE+E+LVK VVSG+IPS+SLE+++ DCYKAA +RREAVQRLTG+SL G+PL GFDY+SI
Sbjct: 162  -EEDEDLVKSVVSGEIPSHSLESKLEDCYKAASIRREAVQRLTGRSLSGMPLDGFDYESI 220

Query: 1375 LGQCCEMPVGYVQIPVGVVGPLLLNGCEYTVPMATTEGCLVASTNRGCKAIYASGGATCV 1196
            LGQCCEMPVGYVQIPVG+ GPLLLN  EY+VPMATTEGCLVASTNRGCKAIYASGGAT +
Sbjct: 221  LGQCCEMPVGYVQIPVGIAGPLLLNDREYSVPMATTEGCLVASTNRGCKAIYASGGATAI 280

Query: 1195 LLRDAMTRAPVVRFSTAKRASELKFFLEDPLNFDTLAVVFNKSSRFGRLQSIQCSIAGKN 1016
            LLRD MTRAPVVRF TAKRASELKFFLEDPLNFDTLAVVFNKSSRF +LQ +QCSIAGKN
Sbjct: 281  LLRDGMTRAPVVRFPTAKRASELKFFLEDPLNFDTLAVVFNKSSRFAKLQGMQCSIAGKN 340

Query: 1015 LYIRFSCSTGDAMGMNMVSKGVQNVLDYLQTDFPDMDVIGISGNFCSDKKPAAVNWIEGR 836
            LYIRF+CSTGDAMGMNMVSKGVQNVLD+LQ+DFPDM+ IG+SGNFCSDKKPAAVNWIEGR
Sbjct: 341  LYIRFNCSTGDAMGMNMVSKGVQNVLDFLQSDFPDMETIGLSGNFCSDKKPAAVNWIEGR 400

Query: 835  GKSVVCEAIISEEXXXXXXXXXXXXXXXLNMLKNXXXXXXXXXXXGFNAHASNIVSAIFL 656
            GKSVVCEAII+EE               LNMLKN           GFNAHASNIVSAIF+
Sbjct: 401  GKSVVCEAIITEEVVNKVLKTTVPALVELNMLKNLTGSAIAGSLGGFNAHASNIVSAIFI 460

Query: 655  ATGQDPAQNVESSHCITMMEAVNDGKDLHVSVTMPSIEVGTIGGGTQLASQSACLNLLGV 476
            ATGQDPAQNVESSHCITMMEAVNDGKDLHVSVTMPSIEVGT+GGGTQLASQSACLNLLGV
Sbjct: 461  ATGQDPAQNVESSHCITMMEAVNDGKDLHVSVTMPSIEVGTVGGGTQLASQSACLNLLGV 520

Query: 475  KGANKESPGTNSRLLATIVAGSVLAGELSLMSAISAGQLVKSHMKYNRSSKDVSQIA 305
            KGA+KE PG+N+R+LATIVAGSVLAGELSLMSAI+AGQLVKSHMKYNRS++D+SQIA
Sbjct: 521  KGASKELPGSNARMLATIVAGSVLAGELSLMSAIAAGQLVKSHMKYNRSTRDMSQIA 577



 Score = 91.3 bits (225), Expect(2) = 0.0
 Identities = 44/55 (80%), Positives = 49/55 (89%)
 Frame = -2

Query: 1853 YLTNTIFFTLFFSVAYFLLIRWREKIHNSTPLHVLTFSELAGLVSLIASFIYLLG 1689
            YLTN IFFTLFFSVAY+LL RWR+KI  STPLHV+T SELA ++SLIASFIYLLG
Sbjct: 50   YLTNGIFFTLFFSVAYYLLHRWRDKIRTSTPLHVVTLSELAAILSLIASFIYLLG 104


>gb|AAD03789.1| 3-hydroxy-3-methylglutaryl-coenzyme A reductase [Morus alba]
          Length = 548

 Score =  684 bits (1766), Expect(2) = 0.0
 Identities = 346/462 (74%), Positives = 391/462 (84%), Gaps = 1/462 (0%)
 Frame = -3

Query: 1687 FFGIDFVQSFVVDSPPRERRRRLDKSVPSKP-ILRMSQGSVVALNCEEEEELVKDVVSGQ 1511
            FFGIDFVQSF++     +     D  V  +    R     V  L  EE+EE+++ VV G 
Sbjct: 86   FFGIDFVQSFIISPRASDDEEDDDLHVVVRDNACRPPPLVVPTLASEEDEEIIRSVVDGT 145

Query: 1510 IPSYSLEARIGDCYKAAFVRREAVQRLTGKSLEGLPLAGFDYDSILGQCCEMPVGYVQIP 1331
            IPSYSLE+R+GDC + A +RREA+QR+TG+S+EGLP+ GFDY+SILGQCCEMPVGYVQIP
Sbjct: 146  IPSYSLESRLGDCKRGAAIRREALQRMTGRSIEGLPIEGFDYESILGQCCEMPVGYVQIP 205

Query: 1330 VGVVGPLLLNGCEYTVPMATTEGCLVASTNRGCKAIYASGGATCVLLRDAMTRAPVVRFS 1151
            VG+ GPLLL+  EY+VPMATTEGCLVASTNRGCKAIY SGGAT VLLRD MTRAPVVRF+
Sbjct: 206  VGIAGPLLLDEFEYSVPMATTEGCLVASTNRGCKAIYMSGGATSVLLRDGMTRAPVVRFN 265

Query: 1150 TAKRASELKFFLEDPLNFDTLAVVFNKSSRFGRLQSIQCSIAGKNLYIRFSCSTGDAMGM 971
            +AKRASELKFF+EDP+NFDTLAVVFN+SSRF RLQ IQC+IAGKN+Y+RFSCSTGDAMGM
Sbjct: 266  SAKRASELKFFVEDPVNFDTLAVVFNRSSRFARLQGIQCAIAGKNVYMRFSCSTGDAMGM 325

Query: 970  NMVSKGVQNVLDYLQTDFPDMDVIGISGNFCSDKKPAAVNWIEGRGKSVVCEAIISEEXX 791
            NMVSKGVQN LDYLQ+DFPDMD+IGISGNFCSDKKPAAVNWIEGRGKSVVCEA+I EE  
Sbjct: 326  NMVSKGVQNALDYLQSDFPDMDIIGISGNFCSDKKPAAVNWIEGRGKSVVCEAVIKEEVV 385

Query: 790  XXXXXXXXXXXXXLNMLKNXXXXXXXXXXXGFNAHASNIVSAIFLATGQDPAQNVESSHC 611
                         LNMLKN           G+NAHASNIVSA+F+ATGQDPAQN+ESSHC
Sbjct: 386  KKVLKTNVDALVELNMLKNLAGSAVAGALGGYNAHASNIVSAVFIATGQDPAQNIESSHC 445

Query: 610  ITMMEAVNDGKDLHVSVTMPSIEVGTIGGGTQLASQSACLNLLGVKGANKESPGTNSRLL 431
            ITMMEAVN+GKDLH+SVTMPSIEVGT+GGGTQLASQSACLNLLGVKGANKES G+N+RLL
Sbjct: 446  ITMMEAVNNGKDLHISVTMPSIEVGTVGGGTQLASQSACLNLLGVKGANKESAGSNARLL 505

Query: 430  ATIVAGSVLAGELSLMSAISAGQLVKSHMKYNRSSKDVSQIA 305
            ATIVAGSVLAGELSLMSAI+AGQLVKSHMKYNRSSKDV+++A
Sbjct: 506  ATIVAGSVLAGELSLMSAIAAGQLVKSHMKYNRSSKDVTKVA 547



 Score = 94.7 bits (234), Expect(2) = 0.0
 Identities = 44/55 (80%), Positives = 50/55 (90%)
 Frame = -2

Query: 1853 YLTNTIFFTLFFSVAYFLLIRWREKIHNSTPLHVLTFSELAGLVSLIASFIYLLG 1689
            YLTN +FFTLFFSVAY+LL RWR+KI NSTPLHV+TF E+A +VSLIASFIYLLG
Sbjct: 31   YLTNAVFFTLFFSVAYYLLHRWRDKIRNSTPLHVVTFPEIAAIVSLIASFIYLLG 85