BLASTX 2.2.25 [Feb-01-2011]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= Lithospermum22_contig00018312
         (3956 letters)

Database: ./nr 
           23,641,837 sequences; 8,123,359,852 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

ref|XP_002272383.2| PREDICTED: niemann-Pick C1 protein-like [Vit...  1541   0.0  
emb|CBI40718.3| unnamed protein product [Vitis vinifera]             1541   0.0  
ref|XP_002510680.1| hedgehog receptor, putative [Ricinus communi...  1506   0.0  
ref|XP_002307793.1| cholesterol transport protein [Populus trich...  1462   0.0  
ref|XP_004145542.1| PREDICTED: niemann-Pick C1 protein-like [Cuc...  1461   0.0  

>ref|XP_002272383.2| PREDICTED: niemann-Pick C1 protein-like [Vitis vinifera]
          Length = 1309

 Score = 1541 bits (3991), Expect = 0.0
 Identities = 772/1091 (70%), Positives = 868/1091 (79%)
 Frame = +2

Query: 317  WFDFIGRQAPPGVPGSPYAINFKPTSPESSGMVPMNVTTYSCTDTSLGCSCGDCPASPVX 496
            WF FIG +A P VPGSPYAINF+P+  ESSGM PMNV+TYSC D SLGCSCGDCP++ V 
Sbjct: 218  WFAFIGTRAAPSVPGSPYAINFQPSIAESSGMKPMNVSTYSCGDNSLGCSCGDCPSASVC 277

Query: 497  XXXXXXXXXXXXXXXVRIGSLKVKCVEVAVTVLYIVLTSMFLGWGFYHRKGGRIPVSRTR 676
                           VRIGSLK KC+E ++ +LYI+L ++F GWG +HR   R P  R +
Sbjct: 278  SGYAPPSLHKEGSCSVRIGSLKAKCIEFSLAILYIILVTIFFGWGLFHRTRERNPAPRMK 337

Query: 677  PLVNVGESGVVRQMSKHKDENVPMQMLEDGPQIAHGVQLSIVQGYMSKFYRRYGTWVARN 856
            P++NV +   +  M++ KDEN+  QMLED PQI +GVQLSIVQGYMS FYRRYGTWVAR+
Sbjct: 338  PMLNVMDGSELHSMNRPKDENLSSQMLEDVPQIRNGVQLSIVQGYMSNFYRRYGTWVARH 397

Query: 857  PILVLCSSLAFVFVLCLGLIRFEVETRPEKLWVGPGSRAAKEKEFFDHHLAPFYRIEQLI 1036
            P ++LCSSLA V VLCLGLIRF+VETRPEKLWVGPGS+AA+EK+FFD HLAPFYRIEQL+
Sbjct: 398  PTIMLCSSLAIVLVLCLGLIRFKVETRPEKLWVGPGSKAAEEKQFFDSHLAPFYRIEQLV 457

Query: 1037 IATLPDTVQGKPPSIITEDNIKLLFDIQKKVDALRANYSGSMISLTDICMKPLGQDCATQ 1216
            +AT+PD   G  PSI+TE+NIKLLF+IQKKVD LRAN+SGSMISLTDICMKPLGQDCATQ
Sbjct: 458  LATIPDA-NGISPSIVTENNIKLLFEIQKKVDGLRANFSGSMISLTDICMKPLGQDCATQ 516

Query: 1217 SIIQYFKMDPKNYDGLGGIEHVEYCFQHFTSADTCMSAFKAPLDPSTSLGGFSGNNFSEA 1396
            S++QYFKMD +NYD  GG++HVEYCFQH+TSADTCMSAFKAPLDPST+LGGFSGNN+SEA
Sbjct: 517  SVLQYFKMDSRNYDDYGGVQHVEYCFQHYTSADTCMSAFKAPLDPSTALGGFSGNNYSEA 576

Query: 1397 SAFIVTYPVNNAVDKESNDTKKAVAWEKAFIQLAKDELMSMALSKNLSLAFSSESSIEEE 1576
            SAFIVTYPVNNA+DKE N+T KAVAWEKAFIQ+ KD+L+ M  SKNL+L+FSSESSIEEE
Sbjct: 577  SAFIVTYPVNNAIDKEGNETGKAVAWEKAFIQIVKDDLLPMMQSKNLTLSFSSESSIEEE 636

Query: 1577 LKRESTADAITIVVSYLVMFAYISLTLGDTPRFSSIYIXXXXXXXXXXXXXXXXXXXXXX 1756
            LKRESTADAITI +SYLVMFAYISLTLGDTPR SS YI                      
Sbjct: 637  LKRESTADAITISISYLVMFAYISLTLGDTPRLSSFYISSKIFLGLAGVMLVMLSVLGSV 696

Query: 1757 XXXXXXXXKSTLIIMEVIPFLVLAVGVDNMCILVHAVKRQPAELPLEGRISNALVEVGPS 1936
                    KSTLIIMEVIPFLVLAVGVDNMCILVHAVKRQP ELPLEGRISNALVEVGPS
Sbjct: 697  GFFSAIGVKSTLIIMEVIPFLVLAVGVDNMCILVHAVKRQPLELPLEGRISNALVEVGPS 756

Query: 1937 ITLASLSEVLAFAVGSFIPMPACRVFSMXXXXXXXXXXXXQVTAFVALIAYDFLRAEDNR 2116
            ITLASL+EVLAFAVG+FIPMPACRVFSM            QVTAFVALI +DFLRAED R
Sbjct: 757  ITLASLAEVLAFAVGTFIPMPACRVFSMFAALAVLLDFLLQVTAFVALIVFDFLRAEDRR 816

Query: 2117 VDCFPCVKISGADADPDKGASQKKLGLLARYMKDIHAPILNIWGVKXXXXXXXXXXXXXX 2296
            +DCFPC+KIS + AD DKG  Q+K GLLARYMK++HAPIL++WGVK              
Sbjct: 817  IDCFPCIKISSSYADSDKGIGQRKPGLLARYMKEVHAPILSLWGVKLVVISVFVAFALAS 876

Query: 2297 XXLCTRIERGLEQQIVLPRNSYLQGYFDDISKYLRIGPPLYFVVKNYNYSSESMHTNQLC 2476
              LCTRIE GLEQ+IVLPR+SYLQGYF+++S+YLRIGPPLYFVVKNYNYSSES HTNQLC
Sbjct: 877  IALCTRIEPGLEQKIVLPRDSYLQGYFNNVSEYLRIGPPLYFVVKNYNYSSESRHTNQLC 936

Query: 2477 SISQCNSDSLLNEITRASLVPETSYIAKPAASWLDDFLVWLSPEAFGCCRKFLNGSYXXX 2656
            SISQCNSDSLLNEI RASL+PE+SYIAKPAASWLDDFLVW+SPEAFGCCRKF NGSY   
Sbjct: 937  SISQCNSDSLLNEIARASLIPESSYIAKPAASWLDDFLVWISPEAFGCCRKFTNGSYCPP 996

Query: 2657 XXXXXXXXXXXXXXXXXXXXKDCTTCFRHSDLQSDRPSTEQFREKLPWFLDSLPSSDCAK 2836
                                KDCTTCFRHSDL +DRPST QFREKLPWFL +LPS+DC+K
Sbjct: 997  NDQPPCCASEDGSCYLNGLCKDCTTCFRHSDLYNDRPSTAQFREKLPWFLAALPSADCSK 1056

Query: 2837 GGKGAYTSSVELKSLEEGIVSASSFRTYHTPLNKQADYVDSMKAARDFSLKVSRSLKMEI 3016
            GG GAYTSSVELK  E GI+ ASSFRTYHTPLNKQ DYV+SM+AAR+F+ +VS SLK++I
Sbjct: 1057 GGHGAYTSSVELKGFESGIIQASSFRTYHTPLNKQIDYVNSMRAAREFTSRVSDSLKIQI 1116

Query: 3017 FPYAVYYMFFEQYLTIWRTALVNLSIAIGAVFIVCFVITCSLWTSAXXXXXXXXXXXXXX 3196
            FPY+V+YMFFEQYL IWRTAL+NL+IAIGAVFIVC VITCSLW+SA              
Sbjct: 1117 FPYSVFYMFFEQYLDIWRTALINLAIAIGAVFIVCLVITCSLWSSAIILLVLAMIVVDLM 1176

Query: 3197 XXXAILGIQLNAVSVVNLVMAVGIGVEFVVHITHAFLVSSGDRNQRMKDSLTTMGASVFS 3376
               AIL IQLNA+SVVNLVMAVGI VEF VHITHAF VSSGDRNQRMK++L TMGASVFS
Sbjct: 1177 GVMAILNIQLNALSVVNLVMAVGIAVEFCVHITHAFSVSSGDRNQRMKEALGTMGASVFS 1236

Query: 3377 GITLTKLVGVIVLCFSRTEVFVVYYFQMYXXXXXXXXXXXXXXXXXXXSMFGPPSRCVLI 3556
            GITLTKLVGVIVLCFSRTEVFVVYYFQMY                   SM GPPSRCVLI
Sbjct: 1237 GITLTKLVGVIVLCFSRTEVFVVYYFQMYLALVLLGFLHGLVFLPVVLSMCGPPSRCVLI 1296

Query: 3557 EKQEDRPSTSS 3589
            +K+ED+PS SS
Sbjct: 1297 DKREDQPSPSS 1307



 Score =  115 bits (289), Expect = 7e-23
 Identities = 52/67 (77%), Positives = 60/67 (89%)
 Frame = +3

Query: 3   FCELTCSPNQSQFINVTSIAKAGNKSTVDGIDYFITDSFGEGLYESCKEVKFGTMNTRAM 182
           FCELTCSPNQS FINVTS++K  N  TVDGI++ ITD+FGEGLY SCK+VKFGTMNTRA+
Sbjct: 146 FCELTCSPNQSLFINVTSVSKVNNNLTVDGIEFIITDAFGEGLYNSCKDVKFGTMNTRAI 205

Query: 183 DFIGSGA 203
           DFIG+GA
Sbjct: 206 DFIGAGA 212


>emb|CBI40718.3| unnamed protein product [Vitis vinifera]
          Length = 1242

 Score = 1541 bits (3991), Expect = 0.0
 Identities = 772/1091 (70%), Positives = 868/1091 (79%)
 Frame = +2

Query: 317  WFDFIGRQAPPGVPGSPYAINFKPTSPESSGMVPMNVTTYSCTDTSLGCSCGDCPASPVX 496
            WF FIG +A P VPGSPYAINF+P+  ESSGM PMNV+TYSC D SLGCSCGDCP++ V 
Sbjct: 151  WFAFIGTRAAPSVPGSPYAINFQPSIAESSGMKPMNVSTYSCGDNSLGCSCGDCPSASVC 210

Query: 497  XXXXXXXXXXXXXXXVRIGSLKVKCVEVAVTVLYIVLTSMFLGWGFYHRKGGRIPVSRTR 676
                           VRIGSLK KC+E ++ +LYI+L ++F GWG +HR   R P  R +
Sbjct: 211  SGYAPPSLHKEGSCSVRIGSLKAKCIEFSLAILYIILVTIFFGWGLFHRTRERNPAPRMK 270

Query: 677  PLVNVGESGVVRQMSKHKDENVPMQMLEDGPQIAHGVQLSIVQGYMSKFYRRYGTWVARN 856
            P++NV +   +  M++ KDEN+  QMLED PQI +GVQLSIVQGYMS FYRRYGTWVAR+
Sbjct: 271  PMLNVMDGSELHSMNRPKDENLSSQMLEDVPQIRNGVQLSIVQGYMSNFYRRYGTWVARH 330

Query: 857  PILVLCSSLAFVFVLCLGLIRFEVETRPEKLWVGPGSRAAKEKEFFDHHLAPFYRIEQLI 1036
            P ++LCSSLA V VLCLGLIRF+VETRPEKLWVGPGS+AA+EK+FFD HLAPFYRIEQL+
Sbjct: 331  PTIMLCSSLAIVLVLCLGLIRFKVETRPEKLWVGPGSKAAEEKQFFDSHLAPFYRIEQLV 390

Query: 1037 IATLPDTVQGKPPSIITEDNIKLLFDIQKKVDALRANYSGSMISLTDICMKPLGQDCATQ 1216
            +AT+PD   G  PSI+TE+NIKLLF+IQKKVD LRAN+SGSMISLTDICMKPLGQDCATQ
Sbjct: 391  LATIPDA-NGISPSIVTENNIKLLFEIQKKVDGLRANFSGSMISLTDICMKPLGQDCATQ 449

Query: 1217 SIIQYFKMDPKNYDGLGGIEHVEYCFQHFTSADTCMSAFKAPLDPSTSLGGFSGNNFSEA 1396
            S++QYFKMD +NYD  GG++HVEYCFQH+TSADTCMSAFKAPLDPST+LGGFSGNN+SEA
Sbjct: 450  SVLQYFKMDSRNYDDYGGVQHVEYCFQHYTSADTCMSAFKAPLDPSTALGGFSGNNYSEA 509

Query: 1397 SAFIVTYPVNNAVDKESNDTKKAVAWEKAFIQLAKDELMSMALSKNLSLAFSSESSIEEE 1576
            SAFIVTYPVNNA+DKE N+T KAVAWEKAFIQ+ KD+L+ M  SKNL+L+FSSESSIEEE
Sbjct: 510  SAFIVTYPVNNAIDKEGNETGKAVAWEKAFIQIVKDDLLPMMQSKNLTLSFSSESSIEEE 569

Query: 1577 LKRESTADAITIVVSYLVMFAYISLTLGDTPRFSSIYIXXXXXXXXXXXXXXXXXXXXXX 1756
            LKRESTADAITI +SYLVMFAYISLTLGDTPR SS YI                      
Sbjct: 570  LKRESTADAITISISYLVMFAYISLTLGDTPRLSSFYISSKIFLGLAGVMLVMLSVLGSV 629

Query: 1757 XXXXXXXXKSTLIIMEVIPFLVLAVGVDNMCILVHAVKRQPAELPLEGRISNALVEVGPS 1936
                    KSTLIIMEVIPFLVLAVGVDNMCILVHAVKRQP ELPLEGRISNALVEVGPS
Sbjct: 630  GFFSAIGVKSTLIIMEVIPFLVLAVGVDNMCILVHAVKRQPLELPLEGRISNALVEVGPS 689

Query: 1937 ITLASLSEVLAFAVGSFIPMPACRVFSMXXXXXXXXXXXXQVTAFVALIAYDFLRAEDNR 2116
            ITLASL+EVLAFAVG+FIPMPACRVFSM            QVTAFVALI +DFLRAED R
Sbjct: 690  ITLASLAEVLAFAVGTFIPMPACRVFSMFAALAVLLDFLLQVTAFVALIVFDFLRAEDRR 749

Query: 2117 VDCFPCVKISGADADPDKGASQKKLGLLARYMKDIHAPILNIWGVKXXXXXXXXXXXXXX 2296
            +DCFPC+KIS + AD DKG  Q+K GLLARYMK++HAPIL++WGVK              
Sbjct: 750  IDCFPCIKISSSYADSDKGIGQRKPGLLARYMKEVHAPILSLWGVKLVVISVFVAFALAS 809

Query: 2297 XXLCTRIERGLEQQIVLPRNSYLQGYFDDISKYLRIGPPLYFVVKNYNYSSESMHTNQLC 2476
              LCTRIE GLEQ+IVLPR+SYLQGYF+++S+YLRIGPPLYFVVKNYNYSSES HTNQLC
Sbjct: 810  IALCTRIEPGLEQKIVLPRDSYLQGYFNNVSEYLRIGPPLYFVVKNYNYSSESRHTNQLC 869

Query: 2477 SISQCNSDSLLNEITRASLVPETSYIAKPAASWLDDFLVWLSPEAFGCCRKFLNGSYXXX 2656
            SISQCNSDSLLNEI RASL+PE+SYIAKPAASWLDDFLVW+SPEAFGCCRKF NGSY   
Sbjct: 870  SISQCNSDSLLNEIARASLIPESSYIAKPAASWLDDFLVWISPEAFGCCRKFTNGSYCPP 929

Query: 2657 XXXXXXXXXXXXXXXXXXXXKDCTTCFRHSDLQSDRPSTEQFREKLPWFLDSLPSSDCAK 2836
                                KDCTTCFRHSDL +DRPST QFREKLPWFL +LPS+DC+K
Sbjct: 930  NDQPPCCASEDGSCYLNGLCKDCTTCFRHSDLYNDRPSTAQFREKLPWFLAALPSADCSK 989

Query: 2837 GGKGAYTSSVELKSLEEGIVSASSFRTYHTPLNKQADYVDSMKAARDFSLKVSRSLKMEI 3016
            GG GAYTSSVELK  E GI+ ASSFRTYHTPLNKQ DYV+SM+AAR+F+ +VS SLK++I
Sbjct: 990  GGHGAYTSSVELKGFESGIIQASSFRTYHTPLNKQIDYVNSMRAAREFTSRVSDSLKIQI 1049

Query: 3017 FPYAVYYMFFEQYLTIWRTALVNLSIAIGAVFIVCFVITCSLWTSAXXXXXXXXXXXXXX 3196
            FPY+V+YMFFEQYL IWRTAL+NL+IAIGAVFIVC VITCSLW+SA              
Sbjct: 1050 FPYSVFYMFFEQYLDIWRTALINLAIAIGAVFIVCLVITCSLWSSAIILLVLAMIVVDLM 1109

Query: 3197 XXXAILGIQLNAVSVVNLVMAVGIGVEFVVHITHAFLVSSGDRNQRMKDSLTTMGASVFS 3376
               AIL IQLNA+SVVNLVMAVGI VEF VHITHAF VSSGDRNQRMK++L TMGASVFS
Sbjct: 1110 GVMAILNIQLNALSVVNLVMAVGIAVEFCVHITHAFSVSSGDRNQRMKEALGTMGASVFS 1169

Query: 3377 GITLTKLVGVIVLCFSRTEVFVVYYFQMYXXXXXXXXXXXXXXXXXXXSMFGPPSRCVLI 3556
            GITLTKLVGVIVLCFSRTEVFVVYYFQMY                   SM GPPSRCVLI
Sbjct: 1170 GITLTKLVGVIVLCFSRTEVFVVYYFQMYLALVLLGFLHGLVFLPVVLSMCGPPSRCVLI 1229

Query: 3557 EKQEDRPSTSS 3589
            +K+ED+PS SS
Sbjct: 1230 DKREDQPSPSS 1240



 Score =  115 bits (289), Expect = 7e-23
 Identities = 52/67 (77%), Positives = 60/67 (89%)
 Frame = +3

Query: 3   FCELTCSPNQSQFINVTSIAKAGNKSTVDGIDYFITDSFGEGLYESCKEVKFGTMNTRAM 182
           FCELTCSPNQS FINVTS++K  N  TVDGI++ ITD+FGEGLY SCK+VKFGTMNTRA+
Sbjct: 79  FCELTCSPNQSLFINVTSVSKVNNNLTVDGIEFIITDAFGEGLYNSCKDVKFGTMNTRAI 138

Query: 183 DFIGSGA 203
           DFIG+GA
Sbjct: 139 DFIGAGA 145


>ref|XP_002510680.1| hedgehog receptor, putative [Ricinus communis]
            gi|223551381|gb|EEF52867.1| hedgehog receptor, putative
            [Ricinus communis]
          Length = 1235

 Score = 1506 bits (3898), Expect = 0.0
 Identities = 755/1092 (69%), Positives = 856/1092 (78%)
 Frame = +2

Query: 317  WFDFIGRQAPPGVPGSPYAINFKPTSPESSGMVPMNVTTYSCTDTSLGCSCGDCPASPVX 496
            WF FIGR+A P +PGSPYAI FK  +P SSGM PMNV+TYSC D SLGCSCGDCP +P+ 
Sbjct: 151  WFTFIGRRAAPNLPGSPYAITFKSAAPASSGMKPMNVSTYSCGDVSLGCSCGDCPTAPIC 210

Query: 497  XXXXXXXXXXXXXXXVRIGSLKVKCVEVAVTVLYIVLTSMFLGWGFYHRKGGRIPVSRTR 676
                           VR GSLK KC++ A+T+LYI+L SM LGWG +HRK  R   S  +
Sbjct: 211  ANTAPHSQHERASCSVRFGSLKAKCIDFALTILYILLVSMLLGWGLFHRKRERDQTSTMK 270

Query: 677  PLVNVGESGVVRQMSKHKDENVPMQMLEDGPQIAHGVQLSIVQGYMSKFYRRYGTWVARN 856
            PL NV + G +  + + KDEN+PMQM E  PQ  + VQLSIVQGYM+KFYRRYGTWVAR+
Sbjct: 271  PLPNVMDGGEIHSVIRRKDENLPMQMGEYSPQTGNRVQLSIVQGYMAKFYRRYGTWVARH 330

Query: 857  PILVLCSSLAFVFVLCLGLIRFEVETRPEKLWVGPGSRAAKEKEFFDHHLAPFYRIEQLI 1036
            PILVL  S+A V +LCLGLIRF+VETRPEKLWVGPGSRAA+EK FFD HLAPFYRIEQLI
Sbjct: 331  PILVLSVSVALVLLLCLGLIRFKVETRPEKLWVGPGSRAAEEKRFFDSHLAPFYRIEQLI 390

Query: 1037 IATLPDTVQGKPPSIITEDNIKLLFDIQKKVDALRANYSGSMISLTDICMKPLGQDCATQ 1216
            IAT P    GK P+I+TE+NIKLLF++QKKVD +RANYSGSMI+L DICMKPL QDCATQ
Sbjct: 391  IATTPKAEDGKLPNIVTENNIKLLFELQKKVDGIRANYSGSMIALNDICMKPLDQDCATQ 450

Query: 1217 SIIQYFKMDPKNYDGLGGIEHVEYCFQHFTSADTCMSAFKAPLDPSTSLGGFSGNNFSEA 1396
            S++QYF+MDP+NY+  GG++H+ YCFQH+TSADTCMSAFKAPLDPST+LGGFSG+N+SEA
Sbjct: 451  SVLQYFQMDPQNYENSGGVDHINYCFQHYTSADTCMSAFKAPLDPSTALGGFSGSNYSEA 510

Query: 1397 SAFIVTYPVNNAVDKESNDTKKAVAWEKAFIQLAKDELMSMALSKNLSLAFSSESSIEEE 1576
            SAFIVTYPVNNA+DKE N+TKKAVAWEKAFIQL KDEL+ M  +KNL+L+FSSESSIEEE
Sbjct: 511  SAFIVTYPVNNAIDKEGNETKKAVAWEKAFIQLVKDELLPMVQAKNLTLSFSSESSIEEE 570

Query: 1577 LKRESTADAITIVVSYLVMFAYISLTLGDTPRFSSIYIXXXXXXXXXXXXXXXXXXXXXX 1756
            LKRESTADAITI++SYLVMFAYISLTLGDTPRFS  Y                       
Sbjct: 571  LKRESTADAITILISYLVMFAYISLTLGDTPRFSFFYFSSKVLLGLSGVMLVVLSVLGSV 630

Query: 1757 XXXXXXXXKSTLIIMEVIPFLVLAVGVDNMCILVHAVKRQPAELPLEGRISNALVEVGPS 1936
                    KSTLIIMEVIPFLVLAVGVDNMCILVHAVKRQP ELPLEGRISNALVEVGPS
Sbjct: 631  GFFSAVGVKSTLIIMEVIPFLVLAVGVDNMCILVHAVKRQPLELPLEGRISNALVEVGPS 690

Query: 1937 ITLASLSEVLAFAVGSFIPMPACRVFSMXXXXXXXXXXXXQVTAFVALIAYDFLRAEDNR 2116
            ITLASLSEVLAFAVGSFIPMPACRVFSM            QVTAFVALI +DFLRAED R
Sbjct: 691  ITLASLSEVLAFAVGSFIPMPACRVFSMFAALAVLLDFLLQVTAFVALIVFDFLRAEDKR 750

Query: 2117 VDCFPCVKISGADADPDKGASQKKLGLLARYMKDIHAPILNIWGVKXXXXXXXXXXXXXX 2296
            VDCFPC+K S + AD DKG   ++ GLLARYMK++HAP+L++WGVK              
Sbjct: 751  VDCFPCLKTSSSYADSDKGIGGRRPGLLARYMKEVHAPVLSLWGVKIVVISIFIAFALAS 810

Query: 2297 XXLCTRIERGLEQQIVLPRNSYLQGYFDDISKYLRIGPPLYFVVKNYNYSSESMHTNQLC 2476
              L TR+E GLEQ+IVLPR+SYLQGYF+++S+YLRIGPPLYFVVKNYNYSSES HTNQLC
Sbjct: 811  VALSTRVEPGLEQKIVLPRDSYLQGYFNNVSEYLRIGPPLYFVVKNYNYSSESRHTNQLC 870

Query: 2477 SISQCNSDSLLNEITRASLVPETSYIAKPAASWLDDFLVWLSPEAFGCCRKFLNGSYXXX 2656
            SISQC+SDSLLNEI RASL P++SYIAKPAASWLDDFLVW+SPEAFGCCRKF NGSY   
Sbjct: 871  SISQCDSDSLLNEIARASLTPKSSYIAKPAASWLDDFLVWISPEAFGCCRKFTNGSY--- 927

Query: 2657 XXXXXXXXXXXXXXXXXXXXKDCTTCFRHSDLQSDRPSTEQFREKLPWFLDSLPSSDCAK 2836
                                KDCTTCFRHSD  +DRPST QFR+KLP FL++LPS+DCAK
Sbjct: 928  -----CPPDDQPPCDVGGVCKDCTTCFRHSDFNNDRPSTTQFRDKLPLFLNALPSADCAK 982

Query: 2837 GGKGAYTSSVELKSLEEGIVSASSFRTYHTPLNKQADYVDSMKAARDFSLKVSRSLKMEI 3016
            GG GAYTSSVEL+  E+G++ ASSFRTYH PLNKQ+DYV+SM+AAR+FS ++S SLK+EI
Sbjct: 983  GGHGAYTSSVELEGYEKGVIQASSFRTYHMPLNKQSDYVNSMRAAREFSSRMSDSLKLEI 1042

Query: 3017 FPYAVYYMFFEQYLTIWRTALVNLSIAIGAVFIVCFVITCSLWTSAXXXXXXXXXXXXXX 3196
            FPY+V+YMFFEQYL IWRTAL+NL+IAIGAVF+VC VITCSLW+SA              
Sbjct: 1043 FPYSVFYMFFEQYLDIWRTALINLAIAIGAVFLVCLVITCSLWSSAIILLVLAMIVIDLM 1102

Query: 3197 XXXAILGIQLNAVSVVNLVMAVGIGVEFVVHITHAFLVSSGDRNQRMKDSLTTMGASVFS 3376
               AIL IQLNAVSVVNLVMAVGI VEF VHITHAF VSSGDR+QR+K++L TMGASVFS
Sbjct: 1103 GVMAILNIQLNAVSVVNLVMAVGIAVEFCVHITHAFSVSSGDRDQRVKEALGTMGASVFS 1162

Query: 3377 GITLTKLVGVIVLCFSRTEVFVVYYFQMYXXXXXXXXXXXXXXXXXXXSMFGPPSRCVLI 3556
            GITLTKLVGV+VLCFSRTEVFVVYYFQMY                   SMFGPPSRC L+
Sbjct: 1163 GITLTKLVGVLVLCFSRTEVFVVYYFQMYLALVLLGFLHGLVFLPVVLSMFGPPSRCKLV 1222

Query: 3557 EKQEDRPSTSSQ 3592
            EK EDRPS S Q
Sbjct: 1223 EKPEDRPSVSLQ 1234



 Score =  115 bits (288), Expect = 1e-22
 Identities = 52/67 (77%), Positives = 62/67 (92%)
 Frame = +3

Query: 3   FCELTCSPNQSQFINVTSIAKAGNKSTVDGIDYFITDSFGEGLYESCKEVKFGTMNTRAM 182
           FCELTCSP+QS FINVTSI+K  N  TVDGID++ITD+FGEGLY+SCK+VKFGTMNTRA+
Sbjct: 79  FCELTCSPHQSLFINVTSISKVKNNLTVDGIDFYITDAFGEGLYDSCKDVKFGTMNTRAL 138

Query: 183 DFIGSGA 203
           +FIG+GA
Sbjct: 139 NFIGAGA 145


>ref|XP_002307793.1| cholesterol transport protein [Populus trichocarpa]
            gi|222857242|gb|EEE94789.1| cholesterol transport protein
            [Populus trichocarpa]
          Length = 1274

 Score = 1462 bits (3786), Expect = 0.0
 Identities = 747/1100 (67%), Positives = 841/1100 (76%), Gaps = 10/1100 (0%)
 Frame = +2

Query: 317  WFDFIGRQAPPGVPGSPYAINFKPTSPESSGMVPMNVTTYSCTDTSLGCSCGDCPASPVX 496
            W+ FIGR+AP  VPGSPYA+ FKPT+PESSG+ PMNV+TYSC D SLGCSCGDCP SPV 
Sbjct: 189  WYAFIGRRAPLDVPGSPYAMTFKPTAPESSGIKPMNVSTYSCGDISLGCSCGDCPQSPVC 248

Query: 497  XXXXXXXXXXXXXXXVRIGSLKVKCVEVAVTVLYIVLTSMFLGWGFYHRKGGRIPVSRTR 676
                              GS   KCV+ A+T+LYI+L SMFLGWG +HRK  R   SR  
Sbjct: 249  ANTAPPPHHEG-------GSCAAKCVDFALTILYIILISMFLGWGLFHRKRERNQTSRMN 301

Query: 677  PLVNVGESGVVRQMSKHKDENVPMQMLEDGPQIAHGVQLSIVQGYMSKFYRRYGTWVARN 856
            PL ++ +SG   ++ + KDEN+P QM+ED PQ    VQLSIVQGYMSKFYRRYGTWVARN
Sbjct: 302  PLSDIKDSG---EVIRKKDENLPAQMVEDSPQTGSRVQLSIVQGYMSKFYRRYGTWVARN 358

Query: 857  PILVLCSSLAFVFVLCLGLIRFEVETRPEKLWVGPGSRAAKEKEFFDHHLAPFYRIEQLI 1036
            PILVL  SLA + +LC+GLIRF+VETRPEKLWVGPGS+ A+EK FFD HLAPFYRIEQLI
Sbjct: 359  PILVLSLSLAVILLLCVGLIRFKVETRPEKLWVGPGSKVAEEKRFFDTHLAPFYRIEQLI 418

Query: 1037 IATLPDTVQGKPPSIITEDNIKLLFDIQKKVDALRANYSGSMISLTDICMKPLGQDCATQ 1216
            +AT+PD    K PSI+TEDNIKLLF+IQKKVD +RANYSGSM+SLTDICMKPL +DCATQ
Sbjct: 419  LATVPDAGAQKLPSIVTEDNIKLLFEIQKKVDGIRANYSGSMVSLTDICMKPLDKDCATQ 478

Query: 1217 SIIQYFKMDPKNYDGLGGIEHVEYCFQHFTSADTCMSAFKAPLDPSTSLGGFSGNNFSEA 1396
            S++QYF+MDP+N +  GG+EHV YC QH+TSADTC SAFKAPLDPSTSLGGFSGNN+SEA
Sbjct: 479  SVLQYFQMDPQNLENYGGVEHVNYCLQHYTSADTCRSAFKAPLDPSTSLGGFSGNNYSEA 538

Query: 1397 SAFIVTYPVNNAVDKESNDTKKAVAWEKAFIQLAKDELMSMALSKNLSLAFSSESSIEEE 1576
            SAFIVTYPVNN +DKE N+T KAVAWEKAFIQL K+EL+ M  SKNL+L+FSSESSIEEE
Sbjct: 539  SAFIVTYPVNNVIDKEGNETDKAVAWEKAFIQLVKNELLPMVQSKNLTLSFSSESSIEEE 598

Query: 1577 LKRESTADAITIVVSYLVMFAYISLTLGDTPRFSSIYIXXXXXXXXXXXXXXXXXXXXXX 1756
            LKRESTAD ITI++SYLVMFAYISLTLGD P  SS YI                      
Sbjct: 599  LKRESTADVITILISYLVMFAYISLTLGDAPHLSSFYISSKVLLGLSGVMLVMLSVLGSV 658

Query: 1757 XXXXXXXXKSTLIIMEVIPFLVLAVGVDNMCILVHAVKRQPAELPLEGRISNALVEVGPS 1936
                    KSTLIIMEVIPFLVLAVGVDNMCILVHAVKRQP ELPLEGRISNALVEVGPS
Sbjct: 659  GFFSAIGVKSTLIIMEVIPFLVLAVGVDNMCILVHAVKRQPLELPLEGRISNALVEVGPS 718

Query: 1937 ITLASLSEVLAFAVGSFIPMPACRVFSMXXXXXXXXXXXXQVTAFVALIAYDFLRAEDNR 2116
            ITLASLSEVLAFA GSFIPMPAC +  +            QVTAFVALI +DFLRAED R
Sbjct: 719  ITLASLSEVLAFAAGSFIPMPACPLAVL-------LDFLLQVTAFVALIVFDFLRAEDKR 771

Query: 2117 VDCFPCVKISGADADPDKGASQKKLGLLARYMKDIHAPILNIWGVKXXXXXXXXXXXXXX 2296
            VDC PC+KIS + AD  KG   ++ GLLARYM++IHAPIL++WGVK              
Sbjct: 772  VDCIPCMKISSSYADTPKGIGGRRPGLLARYMREIHAPILSLWGVKIAVISIFAAFTLAC 831

Query: 2297 XXLCTRIERGLEQQIVLPRNSYLQGYFDDISKYLRIGPPLYFVVKNYNYSSESMHTNQLC 2476
              L TR+E GLEQQIVLP++SYLQGYF+++S+YLRIGPPLYFVVKNYNYSSES HTNQLC
Sbjct: 832  IALTTRVEPGLEQQIVLPQDSYLQGYFNNVSEYLRIGPPLYFVVKNYNYSSESSHTNQLC 891

Query: 2477 SISQCNSDSLLNEITRASLVPETSYIAKPAASWLDDFLVWLSPEAFGCCRKFLNGSYXXX 2656
            SISQC S SLLNEI RASL PE++YIA PAASWLDDFLVW+SPEAFGCCRKF NGSY   
Sbjct: 892  SISQCGSKSLLNEIARASLTPESTYIAMPAASWLDDFLVWISPEAFGCCRKFTNGSYCPP 951

Query: 2657 XXXXXXXXXXXXXXXXXXXXKDCTTCFRHSDLQSDRPSTEQFREKLPWFLDSLPSSDCAK 2836
                                KDCTTCFRHSDL +DRPST QF+EKLP FL++LPS+DCAK
Sbjct: 952  DDQFPCCSSDTGSCGLGGVCKDCTTCFRHSDLNNDRPSTSQFKEKLPLFLNALPSADCAK 1011

Query: 2837 GGKGAYTSSVELKSLEEGIVSASSFRTYHTPLNKQADYVDSMKAARDFSLKVSRSLK--- 3007
            GG GAYTSS++L+  E G++ ASSFRTYHTPLNKQ DYV+SM+AAR+FS +VS SLK   
Sbjct: 1012 GGHGAYTSSIDLQGYENGVIQASSFRTYHTPLNKQIDYVNSMRAAREFSSRVSDSLKKTC 1071

Query: 3008 -------MEIFPYAVYYMFFEQYLTIWRTALVNLSIAIGAVFIVCFVITCSLWTSAXXXX 3166
                   MEIFPY+V+YMFFEQYL IWRTAL+NL+IAIGAVF+VC VITCSLW SA    
Sbjct: 1072 LIVGCMLMEIFPYSVFYMFFEQYLDIWRTALINLAIAIGAVFVVCLVITCSLWNSAIILL 1131

Query: 3167 XXXXXXXXXXXXXAILGIQLNAVSVVNLVMAVGIGVEFVVHITHAFLVSSGDRNQRMKDS 3346
                         AIL IQLNAVSVVNLVM+VGIGVEF VHITHAF VS GDR+QR++D+
Sbjct: 1132 VLAMIVVDLMGVMAILNIQLNAVSVVNLVMSVGIGVEFCVHITHAFSVSCGDRDQRVRDA 1191

Query: 3347 LTTMGASVFSGITLTKLVGVIVLCFSRTEVFVVYYFQMYXXXXXXXXXXXXXXXXXXXSM 3526
            L TMGASVFSGITLTKLVGVIVLCFSRTEVFVVYYFQMY                   SM
Sbjct: 1192 LGTMGASVFSGITLTKLVGVIVLCFSRTEVFVVYYFQMYLALVLLGFLHGLVFLPVVLSM 1251

Query: 3527 FGPPSRCVLIEKQEDRPSTS 3586
            FGPPSRC L+EKQEDR S S
Sbjct: 1252 FGPPSRCKLVEKQEDRLSVS 1271



 Score =  107 bits (266), Expect = 3e-20
 Identities = 48/67 (71%), Positives = 58/67 (86%)
 Frame = +3

Query: 3   FCELTCSPNQSQFINVTSIAKAGNKSTVDGIDYFITDSFGEGLYESCKEVKFGTMNTRAM 182
           FCELTCSP+QS FINVT+ AK     TV GID++ +D+FGEGLYESCK+VKFGTMNTRA+
Sbjct: 117 FCELTCSPHQSTFINVTTTAKVKGNLTVSGIDFYASDAFGEGLYESCKDVKFGTMNTRAL 176

Query: 183 DFIGSGA 203
           +FIG+GA
Sbjct: 177 NFIGAGA 183


>ref|XP_004145542.1| PREDICTED: niemann-Pick C1 protein-like [Cucumis sativus]
          Length = 1244

 Score = 1461 bits (3781), Expect = 0.0
 Identities = 724/1094 (66%), Positives = 850/1094 (77%), Gaps = 2/1094 (0%)
 Frame = +2

Query: 317  WFDFIGRQAPPGVPGSPYAINFKPTSPESSGMVPMNVTTYSCTDTSLGCSCGDCPASPVX 496
            WF FIG+QA PG+PGSPYAI F PT   SSGM  MN + YSC DTSLGCSCGDCP++PV 
Sbjct: 151  WFAFIGKQAGPGLPGSPYAIGFPPTMSVSSGMKHMNASAYSCGDTSLGCSCGDCPSAPVC 210

Query: 497  XXXXXXXXXXXXXXXVRIGSLKVKCVEVAVTVLYIVLTSMFLGWGFYHRKGGRIPVSRTR 676
                           V+IGSLKVKCV+  + +LYI++ S FLGW  ++RK  + P S T+
Sbjct: 211  SSTATPVFHRKNSCSVKIGSLKVKCVDFTLCILYIIIASAFLGWSLFYRKSQKSPSSGTK 270

Query: 677  PLVNVGESGVVRQMSKHKDENVPMQMLEDGPQIAHGVQLSIVQGYMSKFYRRYGTWVARN 856
             + N+ + G +   ++ KDE++PMQMLED PQI   +QLS+VQGYMS FYR+YGTWVARN
Sbjct: 271  TMPNIMDGGSLHSATRKKDESLPMQMLEDAPQIRSRIQLSVVQGYMSNFYRKYGTWVARN 330

Query: 857  PILVLCSSLAFVFVLCLGLIRFEVETRPEKLWVGPGSRAAKEKEFFDHHLAPFYRIEQLI 1036
            P LVL SSLA V +LC+GL+RF+VETRP+KLWVGPGS+A++EKEFFD HLAPFYRIEQ+I
Sbjct: 331  PTLVLISSLAIVLLLCIGLLRFKVETRPDKLWVGPGSKASQEKEFFDSHLAPFYRIEQII 390

Query: 1037 IATLPDTVQGKPPSIITEDNIKLLFDIQKKVDALRANYSGSMISLTDICMKPLGQDCATQ 1216
            IAT+PD+V GKPPSI+ ++N+KLLFDIQKK+D +RANYSG  ISL+DICMKPL Q+CATQ
Sbjct: 391  IATVPDSVHGKPPSILNDNNVKLLFDIQKKIDGIRANYSGRSISLSDICMKPLDQECATQ 450

Query: 1217 SIIQYFKMDPKNYDGLGGIEHVEYCFQHFTSADTCMSAFKAPLDPSTSLGGFSGNNFSEA 1396
            S++QYF+M+P+N D  GG++H+EYCFQH++SAD+C SAF+APLDPST+LGGFSGNN+SEA
Sbjct: 451  SVLQYFQMNPENVDNYGGVDHLEYCFQHYSSADSCRSAFEAPLDPSTALGGFSGNNYSEA 510

Query: 1397 SAFIVTYPVNNAVDKESNDTKKAVAWEKAFIQLAKDELMSMALSKNLSLAFSSESSIEEE 1576
            SAF++TYPVNNA++KE N++  AVAWEKAFIQLAK EL++M  S+NL+L+FSSESSIEEE
Sbjct: 511  SAFLITYPVNNAINKEGNESGPAVAWEKAFIQLAKAELLTMTQSQNLTLSFSSESSIEEE 570

Query: 1577 LKRESTADAITIVVSYLVMFAYISLTLGDTPRFSSIYIXXXXXXXXXXXXXXXXXXXXXX 1756
            LKRESTAD ITI++SYLVMFAYISLTLGD P  S+ Y+                      
Sbjct: 571  LKRESTADVITILISYLVMFAYISLTLGDRPHLSTFYVSSKVLLGLSGVVLVMLSVLASV 630

Query: 1757 XXXXXXXXKSTLIIMEVIPFLVLAVGVDNMCILVHAVKRQPAELPLEGRISNALVEVGPS 1936
                    KSTLIIMEVIPFLVLAVGVDNMCILVHAVKRQ  ELPLEGRISNALVEVGPS
Sbjct: 631  GFFSAIGVKSTLIIMEVIPFLVLAVGVDNMCILVHAVKRQSVELPLEGRISNALVEVGPS 690

Query: 1937 ITLASLSEVLAFAVGSFIPMPACRVFSMXXXXXXXXXXXXQVTAFVALIAYDFLRAEDNR 2116
            ITLASLSEVLAFAVGSFIPMPACRVFSM            QVTAFVALI +DFLR ED R
Sbjct: 691  ITLASLSEVLAFAVGSFIPMPACRVFSMFAALAVLLDFLLQVTAFVALIVFDFLRTEDKR 750

Query: 2117 VDCFPCVKISGADADPDKGASQKKLGLLARYMKDIHAPILNIWGVKXXXXXXXXXXXXXX 2296
            VDCFPC+K S   A  DKG +QK  GLLARYMK+IHAP L+IW VK              
Sbjct: 751  VDCFPCIK-SSRYAGSDKGITQKNPGLLARYMKEIHAPALSIWIVKIIVISIFVGFTLAS 809

Query: 2297 XXLCTRIERGLEQQIVLPRNSYLQGYFDDISKYLRIGPPLYFVVKNYNYSSESMHTNQLC 2476
              LCTRIE GLEQ+IVLP++SYLQGYF++IS++LRIGPP+YFVVKNYNYSSES  TNQLC
Sbjct: 810  IALCTRIEAGLEQKIVLPKDSYLQGYFNNISEHLRIGPPVYFVVKNYNYSSESRQTNQLC 869

Query: 2477 SISQCNSDSLLNEITRASLVPETSYIAKPAASWLDDFLVWLSPEAFGCCRKFLNGSY--X 2650
            SISQC+SDSLLNEI +ASL+PE+S+IAKPAASWLDD+LVW+SPEAFGCCRKF NGSY   
Sbjct: 870  SISQCDSDSLLNEIAKASLIPESSFIAKPAASWLDDYLVWISPEAFGCCRKFTNGSYCPP 929

Query: 2651 XXXXXXXXXXXXXXXXXXXXXXKDCTTCFRHSDLQSDRPSTEQFREKLPWFLDSLPSSDC 2830
                                  KDCTTCF HSDL   RPST QF+EKLPWFL +LPS+DC
Sbjct: 930  DDQPPCCTSSGGGGSCGLNGVCKDCTTCFLHSDLNGGRPSTAQFKEKLPWFLSALPSADC 989

Query: 2831 AKGGKGAYTSSVELKSLEEGIVSASSFRTYHTPLNKQADYVDSMKAARDFSLKVSRSLKM 3010
            AKGG GAYTSSV+LK  E G++ ASSFRTYHTPLNKQ DY++SM+AA++ S ++S SLK+
Sbjct: 990  AKGGHGAYTSSVDLKDYENGVIQASSFRTYHTPLNKQVDYINSMRAAQELSSRLSDSLKI 1049

Query: 3011 EIFPYAVYYMFFEQYLTIWRTALVNLSIAIGAVFIVCFVITCSLWTSAXXXXXXXXXXXX 3190
            EIFPY+V+YMFFEQYL IWRTAL+NL+IAIGAVFIVC +ITCSLWTSA            
Sbjct: 1050 EIFPYSVFYMFFEQYLNIWRTALINLAIAIGAVFIVCLIITCSLWTSAIILLVLAMIIVD 1109

Query: 3191 XXXXXAILGIQLNAVSVVNLVMAVGIGVEFVVHITHAFLVSSGDRNQRMKDSLTTMGASV 3370
                 AIL IQLNA+SVVNLVM+VGI VEF VH+THAF VSSGDRNQRMK++L+TMGASV
Sbjct: 1110 LMGVMAILNIQLNAISVVNLVMSVGIAVEFCVHLTHAFSVSSGDRNQRMKEALSTMGASV 1169

Query: 3371 FSGITLTKLVGVIVLCFSRTEVFVVYYFQMYXXXXXXXXXXXXXXXXXXXSMFGPPSRCV 3550
             SGITLTKLVGV+VLCFSRTEVFVVYYF +Y                   S+FGPPSRCV
Sbjct: 1170 LSGITLTKLVGVLVLCFSRTEVFVVYYFHVYLALVLLGFLHGLVFLPVVLSLFGPPSRCV 1229

Query: 3551 LIEKQEDRPSTSSQ 3592
             +E+Q++RPSTSSQ
Sbjct: 1230 FVEQQDNRPSTSSQ 1243



 Score =  112 bits (279), Expect = 1e-21
 Identities = 50/67 (74%), Positives = 57/67 (85%)
 Frame = +3

Query: 3   FCELTCSPNQSQFINVTSIAKAGNKSTVDGIDYFITDSFGEGLYESCKEVKFGTMNTRAM 182
           FCELTCSPNQS FINVTS+ K  N  TVD IDY++ D+FGEGLYESCK+VK+GTMNTRAM
Sbjct: 79  FCELTCSPNQSLFINVTSVLKVNNSLTVDAIDYYVADAFGEGLYESCKDVKYGTMNTRAM 138

Query: 183 DFIGSGA 203
            FIG+ A
Sbjct: 139 QFIGADA 145