BLASTX 2.2.25 [Feb-01-2011]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= Lithospermum22_contig00017044
         (2023 letters)

Database: ./nr 
           23,641,837 sequences; 8,123,359,852 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gb|ABE27875.1| hydroxymethylglutaryl-coenzyme A reductase [Arneb...   942   0.0  
gb|ADX31913.1| HMG CoA reductase [Bacopa monnieri]                    826   0.0  
gb|ADX31914.1| HMG CoA reductase [Bacopa monnieri]                    823   0.0  
sp|P48021.1|HMDH_CAMAC RecName: Full=3-hydroxy-3-methylglutaryl-...   820   0.0  
gb|AAL54878.1|AF004232_1 hydroxy-methyl-glutaryl-coenzyme A redu...   818   0.0  

>gb|ABE27875.1| hydroxymethylglutaryl-coenzyme A reductase [Arnebia euchroma]
          Length = 562

 Score =  942 bits (2434), Expect = 0.0
 Identities = 499/571 (87%), Positives = 514/571 (90%), Gaps = 13/571 (2%)
 Frame = +2

Query: 146  MEYSKSMNKDTTSLKKNNVELDFSRKASDAFSLPIRFANAIFFPLFFSVVYYLLTRWREK 325
            MEYSKSMNKDTTSLKK NVELDFSRKAS+AFSLP+RFANAIFFPLFFSVVYYLL RWREK
Sbjct: 1    MEYSKSMNKDTTSLKKQNVELDFSRKASEAFSLPLRFANAIFFPLFFSVVYYLLMRWREK 60

Query: 326  IRNSTPLHVVSLHEILAIVALVASSIYLHGFLSIGLIQLS-----EEEEEAHIYGTKEVN 490
            IRNSTPLHVVS HEILAIVALVASSIYL GFLSIGL+QLS     EEEEE  +Y TK+VN
Sbjct: 61   IRNSTPLHVVSFHEILAIVALVASSIYLLGFLSIGLVQLSGEDEEEEEEEVPLYDTKDVN 120

Query: 491  KDIQV------EEKCDVACTTAASASPKEMIKCCPEEDEEIVQSVVQGKTPSYSLESKLG 652
            KDIQV      EEKC VAC +  +ASPK M K CPEEDEEIVQSVVQG TPSYSLESKLG
Sbjct: 121  KDIQVDRVTLMEEKCHVACIS--TASPKPMAKYCPEEDEEIVQSVVQGNTPSYSLESKLG 178

Query: 653  DCFRAAAIRREALQRVTGKSLEGLPLEHFDYDSILGQCCEMPIGYVQLPVGIAGPLLLDV 832
            DCFRAAAIRREALQR+TGKSLEGLPLEHFDYDSILGQCCEMPIGYVQLPVGIAGPLLLD 
Sbjct: 179  DCFRAAAIRREALQRLTGKSLEGLPLEHFDYDSILGQCCEMPIGYVQLPVGIAGPLLLDD 238

Query: 833  KEYSVPMATTEGCLVASTNRGCKAIYASGGATSVVLRDAMTRAPVVRFGTAKRAAEVKFF 1012
            KEYSVPMATTEGCLVASTNRGCKAIYASGGATSVVLRD MTRAPVVRFGTAKRAAE+KFF
Sbjct: 239  KEYSVPMATTEGCLVASTNRGCKAIYASGGATSVVLRDGMTRAPVVRFGTAKRAAELKFF 298

Query: 1013 LEDPLNFETLSAVFNQSSRFGRLQSIKCAIAGKNLYMRFSCSTGDAMGMNMVSKGTQHVI 1192
            LEDPLNFETLSAVFNQSSRFGRLQSIKCAIAGKNLYMRFSCSTGDAMGMNMVSKGTQHVI
Sbjct: 299  LEDPLNFETLSAVFNQSSRFGRLQSIKCAIAGKNLYMRFSCSTGDAMGMNMVSKGTQHVI 358

Query: 1193 EFLEKEFPDMDVIGISGNYCSDKKPAAVNWIEGRSKSVVCEAIIPEEVVKNVLKT--DVA 1366
            EFLEKEFPDMDVIGISGNYCSDKKPAAVNWIEGR KSVVCEAII E+VVK VLKT     
Sbjct: 359  EFLEKEFPDMDVIGISGNYCSDKKPAAVNWIEGRGKSVVCEAII-EDVVKKVLKTMCSCG 417

Query: 1367 SLVELNMLKNLTGSAMAGALGGFNAHASNIVSAIFIATGQDPAQNIESSHCITMMEAVND 1546
            +L    +L    G      L   NAHASNIVSAIFIATGQDPAQNIESSHCITMMEAVN+
Sbjct: 418  ALHAQELLSQWRG------LWWINAHASNIVSAIFIATGQDPAQNIESSHCITMMEAVNE 471

Query: 1547 GKDLHVSVTMPSIEVGTVGGGTQLASQAACLNLLGVKGANRGSPGANARRLATIVAGSVL 1726
            GKDLHVSVTMPSIEVGTVGGGTQLASQAACLNLLGVKGANR  PGANAR+LA IVAGSVL
Sbjct: 472  GKDLHVSVTMPSIEVGTVGGGTQLASQAACLNLLGVKGANRECPGANARQLAAIVAGSVL 531

Query: 1727 AGELSLMSAISAGQLVKSHMKYNRSTKDVSK 1819
            AGELSLMSAI+AGQLVKSHMKYNRS KDVSK
Sbjct: 532  AGELSLMSAIAAGQLVKSHMKYNRSNKDVSK 562


>gb|ADX31913.1| HMG CoA reductase [Bacopa monnieri]
          Length = 589

 Score =  826 bits (2133), Expect = 0.0
 Identities = 426/556 (76%), Positives = 478/556 (85%), Gaps = 23/556 (4%)
 Frame = +2

Query: 221  KASDAFSLPIRFANAIFFPLFFSVVYYLLTRWREKIRNSTPLHVVSLHEILAIVALVASS 400
            KASDA  LP+ F NA+F  LFFSVVYYLL RWREKIRNSTPLHVV+L EI AIV  VAS 
Sbjct: 30   KASDALPLPLAFTNAVFITLFFSVVYYLLRRWREKIRNSTPLHVVTLSEIAAIVTFVASF 89

Query: 401  IYLHGFLSIGLIQ------------LSEEEEEAHIYGTKEVNKDIQVEEKCDVACTTAAS 544
            IYL GF  +G +Q            L E++E       +++ K+      C  A  +  S
Sbjct: 90   IYLIGFFGVGFVQSLIIPRASHDDILGEDDEIVDGDLDRQMLKEDSRSAPCAAALPSVDS 149

Query: 545  ---ASPK------EMIKCCP--EEDEEIVQSVVQGKTPSYSLESKLGDCFRAAAIRREAL 691
               ASP+      ++I   P  EEDEEI++SVV+GKTPSYSLESKLGDC RAAAIRREAL
Sbjct: 150  GKLASPRSKVHGGDLIVTPPASEEDEEIIKSVVEGKTPSYSLESKLGDCRRAAAIRREAL 209

Query: 692  QRVTGKSLEGLPLEHFDYDSILGQCCEMPIGYVQLPVGIAGPLLLDVKEYSVPMATTEGC 871
            QR TGKSL+GLPL+ F+YDSILGQCCEMP+GYVQ+PVGIAGPLLL+ KEYSVPMATTEGC
Sbjct: 210  QRTTGKSLDGLPLDGFNYDSILGQCCEMPVGYVQIPVGIAGPLLLNGKEYSVPMATTEGC 269

Query: 872  LVASTNRGCKAIYASGGATSVVLRDAMTRAPVVRFGTAKRAAEVKFFLEDPLNFETLSAV 1051
            LVASTNRGCKAI+ASGGA+SV+L+D MTRAPVVRFGTAKRAAE+KFFLEDPLNFE LS +
Sbjct: 270  LVASTNRGCKAIFASGGASSVILKDGMTRAPVVRFGTAKRAAELKFFLEDPLNFEPLSLI 329

Query: 1052 FNQSSRFGRLQSIKCAIAGKNLYMRFSCSTGDAMGMNMVSKGTQHVIEFLEKEFPDMDVI 1231
            FN SSRFGRLQSIKCA+AGKNLYMRF+CSTGDAMGMNMVSKG Q+V++FL KEFPDMDVI
Sbjct: 330  FNSSSRFGRLQSIKCAVAGKNLYMRFTCSTGDAMGMNMVSKGVQNVMDFLNKEFPDMDVI 389

Query: 1232 GISGNYCSDKKPAAVNWIEGRSKSVVCEAIIPEEVVKNVLKTDVASLVELNMLKNLTGSA 1411
            GISGNYCSDKKPAAVNWIEG  KSVVCEAII E+VVK VLKTDVASLVELNMLKNLTGSA
Sbjct: 390  GISGNYCSDKKPAAVNWIEGTGKSVVCEAIIKEDVVKKVLKTDVASLVELNMLKNLTGSA 449

Query: 1412 MAGALGGFNAHASNIVSAIFIATGQDPAQNIESSHCITMMEAVNDGKDLHVSVTMPSIEV 1591
            MAGALGGFNAHASNIVSA++IATGQDPAQN+ESSHCITMMEAVNDGKDLH+SVTMPSIE+
Sbjct: 450  MAGALGGFNAHASNIVSAVYIATGQDPAQNVESSHCITMMEAVNDGKDLHISVTMPSIEI 509

Query: 1592 GTVGGGTQLASQAACLNLLGVKGANRGSPGANARRLATIVAGSVLAGELSLMSAISAGQL 1771
            GTVGGGTQLASQ+ACLNLLGVKGA++ +PG+N+R+LATIVAG+VLAGELSLMSA++AGQL
Sbjct: 510  GTVGGGTQLASQSACLNLLGVKGASKDAPGSNSRQLATIVAGAVLAGELSLMSALAAGQL 569

Query: 1772 VKSHMKYNRSTKDVSK 1819
            VKSHMKYNRS+KDVSK
Sbjct: 570  VKSHMKYNRSSKDVSK 585


>gb|ADX31914.1| HMG CoA reductase [Bacopa monnieri]
          Length = 589

 Score =  823 bits (2125), Expect = 0.0
 Identities = 422/556 (75%), Positives = 476/556 (85%), Gaps = 23/556 (4%)
 Frame = +2

Query: 221  KASDAFSLPIRFANAIFFPLFFSVVYYLLTRWREKIRNSTPLHVVSLHEILAIVALVASS 400
            KASDA  LP+ F NA+F  LFFSVVYYLL RWREKIRNSTPLHVV+L EI AIV  VAS 
Sbjct: 30   KASDALPLPLAFTNAVFITLFFSVVYYLLRRWREKIRNSTPLHVVTLSEIAAIVTFVASF 89

Query: 401  IYLHGFLSIGLIQ------------LSEEEEEAHIYGTKEVNKDIQVEEKCDVACTTAAS 544
            IYL GF  +G +Q            L E++E        ++ K+      C  A  +  S
Sbjct: 90   IYLIGFFGVGFVQSLIIPRASHDDILGEDDEIVDGDLDHQMLKEDSRSAPCAAALPSVDS 149

Query: 545  ---ASPKEMIK--------CCPEEDEEIVQSVVQGKTPSYSLESKLGDCFRAAAIRREAL 691
               ASP+  +            EEDEEI++SVV+GKTPSYSLESKLGDC RAAAIRREAL
Sbjct: 150  GKLASPRSKVHGGDLIVTPSVSEEDEEIIKSVVEGKTPSYSLESKLGDCRRAAAIRREAL 209

Query: 692  QRVTGKSLEGLPLEHFDYDSILGQCCEMPIGYVQLPVGIAGPLLLDVKEYSVPMATTEGC 871
            QR TGKSL+GLPL+ F+YDSILGQCCEMP+GYVQ+PVGIAGPLLL+ KE+SVPMATT+GC
Sbjct: 210  QRTTGKSLDGLPLDGFNYDSILGQCCEMPVGYVQIPVGIAGPLLLNGKEFSVPMATTKGC 269

Query: 872  LVASTNRGCKAIYASGGATSVVLRDAMTRAPVVRFGTAKRAAEVKFFLEDPLNFETLSAV 1051
            LVASTNRGCKAI+ASGGA+SV+L+D MTRAPVVRFGTAKRAAE+KFFLEDPLNFE+LS +
Sbjct: 270  LVASTNRGCKAIFASGGASSVILKDGMTRAPVVRFGTAKRAAELKFFLEDPLNFESLSLI 329

Query: 1052 FNQSSRFGRLQSIKCAIAGKNLYMRFSCSTGDAMGMNMVSKGTQHVIEFLEKEFPDMDVI 1231
            FN SSRFGRLQSIKCA+AGKNLYMRF+CSTGDAMGMNMVSKG Q+V++FL KEFPDMD+I
Sbjct: 330  FNSSSRFGRLQSIKCAVAGKNLYMRFTCSTGDAMGMNMVSKGVQNVMDFLNKEFPDMDII 389

Query: 1232 GISGNYCSDKKPAAVNWIEGRSKSVVCEAIIPEEVVKNVLKTDVASLVELNMLKNLTGSA 1411
            GISGNYCSDKKPAAVNWIEGR KSVVCEAII E+VVK VLKTDVASLVELNMLKNLTGSA
Sbjct: 390  GISGNYCSDKKPAAVNWIEGRGKSVVCEAIIKEDVVKKVLKTDVASLVELNMLKNLTGSA 449

Query: 1412 MAGALGGFNAHASNIVSAIFIATGQDPAQNIESSHCITMMEAVNDGKDLHVSVTMPSIEV 1591
            MAGALGGFNAHAS+IVSA++IATGQDPAQN+ESSHCITMMEAVNDGKDLH+SVTMPSIEV
Sbjct: 450  MAGALGGFNAHASSIVSAVYIATGQDPAQNVESSHCITMMEAVNDGKDLHISVTMPSIEV 509

Query: 1592 GTVGGGTQLASQAACLNLLGVKGANRGSPGANARRLATIVAGSVLAGELSLMSAISAGQL 1771
            GTVGGGTQLASQ+ACLNLLGVKGA++ +PG+N+R+LATIVAG+VLAGELSLMSA++AGQL
Sbjct: 510  GTVGGGTQLASQSACLNLLGVKGASKDAPGSNSRQLATIVAGAVLAGELSLMSALAAGQL 569

Query: 1772 VKSHMKYNRSTKDVSK 1819
            VKSHMKYNRS+KDVSK
Sbjct: 570  VKSHMKYNRSSKDVSK 585


>sp|P48021.1|HMDH_CAMAC RecName: Full=3-hydroxy-3-methylglutaryl-coenzyme A reductase;
            Short=HMG-CoA reductase gi|289881|gb|AAA33040.1|
            3-hydroxy-3-methylglutaryl coA reductase [Camptotheca
            acuminata]
          Length = 593

 Score =  820 bits (2118), Expect = 0.0
 Identities = 424/568 (74%), Positives = 479/568 (84%), Gaps = 15/568 (2%)
 Frame = +2

Query: 164  MNKDTTSLKKNNVELDFSRKASDAFSLPIRFANAIFFPLFFSVVYYLLTRWREKIRNSTP 343
            M K     K + V+L  S KASDA  LP+   N +FF LFF+VVYYLL RWREKIRNSTP
Sbjct: 24   MLKPKQPTKVDAVDLPDSPKASDALPLPLYITNGVFFTLFFTVVYYLLVRWREKIRNSTP 83

Query: 344  LHVVSLHEILAIVALVASSIYLHGFLSIGLIQ-LSEEEEEAHIYGT---KEVNKDIQVEE 511
            LHVV+L EI AI   VAS IYL GF  IGL+Q  +       ++G    ++V++ +  E+
Sbjct: 84   LHVVTLSEIAAIFTFVASFIYLLGFFGIGLVQPFTSRSSHDDVWGVDDDEDVDEIVLKED 143

Query: 512  KCDVACTTAASASPKEMIKC-----------CPEEDEEIVQSVVQGKTPSYSLESKLGDC 658
               V C  A    P   IK              EEDEEI++SVV+G TPSY+LESKLGD 
Sbjct: 144  TRTVPCAAAPVDCPLPPIKPKVVDPVPISPPSSEEDEEIIKSVVEGTTPSYALESKLGDS 203

Query: 659  FRAAAIRREALQRVTGKSLEGLPLEHFDYDSILGQCCEMPIGYVQLPVGIAGPLLLDVKE 838
             RAAAIRREALQR+T KSL GLPL+ FDYDSILGQCCEMP+GYVQ+PVGIAGPLLLD +E
Sbjct: 204  HRAAAIRREALQRMTKKSLAGLPLDGFDYDSILGQCCEMPVGYVQIPVGIAGPLLLDGRE 263

Query: 839  YSVPMATTEGCLVASTNRGCKAIYASGGATSVVLRDAMTRAPVVRFGTAKRAAEVKFFLE 1018
            YSVPMATTEGCLVASTNRGCKAI+A GGATSV+LRDAMTRAPVVRFG+AKRAA++KFFLE
Sbjct: 264  YSVPMATTEGCLVASTNRGCKAIFACGGATSVLLRDAMTRAPVVRFGSAKRAADLKFFLE 323

Query: 1019 DPLNFETLSAVFNQSSRFGRLQSIKCAIAGKNLYMRFSCSTGDAMGMNMVSKGTQHVIEF 1198
            +PLNFETL+AVFN SSRFG+LQ+IKCAIAGKNLYMR+SCSTGDAMGMNM+SKG Q+V++F
Sbjct: 324  NPLNFETLAAVFNSSSRFGKLQNIKCAIAGKNLYMRYSCSTGDAMGMNMISKGVQNVLDF 383

Query: 1199 LEKEFPDMDVIGISGNYCSDKKPAAVNWIEGRSKSVVCEAIIPEEVVKNVLKTDVASLVE 1378
            L+ +FPDMDVIGISGNYCSDKKPAAVNWIEGR KSVVCEA+I EEVVK VLKT+VASLVE
Sbjct: 384  LQDDFPDMDVIGISGNYCSDKKPAAVNWIEGRGKSVVCEAVIKEEVVKKVLKTNVASLVE 443

Query: 1379 LNMLKNLTGSAMAGALGGFNAHASNIVSAIFIATGQDPAQNIESSHCITMMEAVNDGKDL 1558
            LNMLKNLTGSAMAGALGGFNAHASNIVSA+++ATGQDPAQN+ESSHCITMMEA+NDGKDL
Sbjct: 444  LNMLKNLTGSAMAGALGGFNAHASNIVSAVYLATGQDPAQNVESSHCITMMEAINDGKDL 503

Query: 1559 HVSVTMPSIEVGTVGGGTQLASQAACLNLLGVKGANRGSPGANARRLATIVAGSVLAGEL 1738
            HVSVTMPSIEVGTVGGGTQLASQ+ACLNLLGVKGA++ +PG+NAR LATIVAGSVLAGEL
Sbjct: 504  HVSVTMPSIEVGTVGGGTQLASQSACLNLLGVKGASKEAPGSNARLLATIVAGSVLAGEL 563

Query: 1739 SLMSAISAGQLVKSHMKYNRSTKDVSKA 1822
            SLMSAI+AGQLV SHMKYNRS KDV+KA
Sbjct: 564  SLMSAIAAGQLVNSHMKYNRSNKDVTKA 591


>gb|AAL54878.1|AF004232_1 hydroxy-methyl-glutaryl-coenzyme A reductase [Nicotiana tabacum]
          Length = 604

 Score =  818 bits (2112), Expect = 0.0
 Identities = 423/563 (75%), Positives = 473/563 (84%), Gaps = 30/563 (5%)
 Frame = +2

Query: 224  ASDAFSLPIRFANAIFFPLFFSVVYYLLTRWREKIRNSTPLHVVSLHEILAIVALVASSI 403
            ASDA  LP+   N +FF +FFSV+YYLL+RWREKIRNSTPLHVV+  E++AIV+L+AS I
Sbjct: 40   ASDALPLPLYLTNGLFFTMFFSVMYYLLSRWREKIRNSTPLHVVTFSELVAIVSLIASVI 99

Query: 404  YLHGFLSIGLIQ--LSEEEEEAHIYGTKEVNKDIQVEE------KCDVACTTAASASPKE 559
            YL GF  IG +Q  +S +  +       E ++   +EE         + CT       ++
Sbjct: 100  YLLGFFGIGFVQSFVSRDNNDDSWDVEDENDEQFLLEEDSRRGPATTLGCTAVPPPPARQ 159

Query: 560  MIKCCP----------------------EEDEEIVQSVVQGKTPSYSLESKLGDCFRAAA 673
            ++   P                      EEDEEI++SVVQGK PSYSLESKLGDC RAA+
Sbjct: 160  VVPMVPPQPAKVAAMSEKPAPLVTPAASEEDEEIIKSVVQGKMPSYSLESKLGDCKRAAS 219

Query: 674  IRREALQRVTGKSLEGLPLEHFDYDSILGQCCEMPIGYVQLPVGIAGPLLLDVKEYSVPM 853
            IR+EALQR+TGKSLEGLPLE FDY+SILGQCCEMPIGYVQ+PVGIAGPLLLD +EYSVPM
Sbjct: 220  IRKEALQRITGKSLEGLPLEGFDYESILGQCCEMPIGYVQIPVGIAGPLLLDGREYSVPM 279

Query: 854  ATTEGCLVASTNRGCKAIYASGGATSVVLRDAMTRAPVVRFGTAKRAAEVKFFLEDPLNF 1033
            ATTEGCLVASTNRGCKAIYASGGATSV+LRD MTRAP VRFGTAKRAAE+KFF+EDP+ F
Sbjct: 280  ATTEGCLVASTNRGCKAIYASGGATSVLLRDGMTRAPCVRFGTAKRAAELKFFVEDPVKF 339

Query: 1034 ETLSAVFNQSSRFGRLQSIKCAIAGKNLYMRFSCSTGDAMGMNMVSKGTQHVIEFLEKEF 1213
            ETL+AVFNQSSRF RLQ I+CAIAGKNLYMRF CSTGDAMGMNMVSKG Q+V+++L+ E+
Sbjct: 340  ETLAAVFNQSSRFARLQRIQCAIAGKNLYMRFVCSTGDAMGMNMVSKGVQNVLDYLQNEY 399

Query: 1214 PDMDVIGISGNYCSDKKPAAVNWIEGRSKSVVCEAIIPEEVVKNVLKTDVASLVELNMLK 1393
            PDMDVIGISGN+CSDKKPAAVNWIEGR KSVVCEAII EEVVK VLKT+VA+LVE NMLK
Sbjct: 400  PDMDVIGISGNFCSDKKPAAVNWIEGRGKSVVCEAIITEEVVKKVLKTEVAALVEPNMLK 459

Query: 1394 NLTGSAMAGALGGFNAHASNIVSAIFIATGQDPAQNIESSHCITMMEAVNDGKDLHVSVT 1573
            NLTGSAMAGALGGFNAHASNIVSA+FIATGQDPAQNIESSHCITMMEAVNDGKDLHVSVT
Sbjct: 460  NLTGSAMAGALGGFNAHASNIVSAVFIATGQDPAQNIESSHCITMMEAVNDGKDLHVSVT 519

Query: 1574 MPSIEVGTVGGGTQLASQAACLNLLGVKGANRGSPGANARRLATIVAGSVLAGELSLMSA 1753
            MPSIEVGTVGGGTQLASQ+ACLNLLGVKGANR +PG+NAR LATIVAGSVLAGELSLMSA
Sbjct: 520  MPSIEVGTVGGGTQLASQSACLNLLGVKGANREAPGSNARLLATIVAGSVLAGELSLMSA 579

Query: 1754 ISAGQLVKSHMKYNRSTKDVSKA 1822
            ISAGQLVKSHMKYNRSTKDV+KA
Sbjct: 580  ISAGQLVKSHMKYNRSTKDVTKA 602