BLASTX 2.2.25 [Feb-01-2011]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= Lithospermum22_contig00001506
         (2425 letters)

Database: ./nr 
           23,641,837 sequences; 8,123,359,852 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

ref|XP_002528078.1| Myosin heavy chain, putative [Ricinus commun...   383   e-103
ref|XP_003551836.1| PREDICTED: protein PLASTID MOVEMENT IMPAIRED...   371   e-100
ref|XP_002281016.2| PREDICTED: protein PLASTID MOVEMENT IMPAIRED...   370   1e-99
ref|XP_003520017.1| PREDICTED: protein PLASTID MOVEMENT IMPAIRED...   366   1e-98
ref|XP_002303000.1| predicted protein [Populus trichocarpa] gi|2...   366   2e-98

>ref|XP_002528078.1| Myosin heavy chain, putative [Ricinus communis]
            gi|223532539|gb|EEF34328.1| Myosin heavy chain, putative
            [Ricinus communis]
          Length = 650

 Score =  383 bits (983), Expect = e-103
 Identities = 246/646 (38%), Positives = 367/646 (56%), Gaps = 37/646 (5%)
 Frame = -2

Query: 2130 MSTGGYEERQEIGSVKAAIDFY-----KGKMPMKQQSNYSEKQPPSKTGELHRARRKSGL 1966
            M    +++R+ IG+VKAAI+ Y     +G   +++      +Q  S+  ELH A+R    
Sbjct: 1    MDRRAFDDRRRIGTVKAAINMYGERILEGSSSLRKSQKDLPEQSSSRAKELHLAKRNMAR 60

Query: 1965 LQDARGVADSVKSQAERELLSAXXXXXXXXXXXXESNLSAKAQIEAMEKLQKTKRGARRN 1786
             +++R +A+SVK+QAE EL  A            ESN   KA++  +E L+K+ +  R  
Sbjct: 61   YKESRKIAESVKNQAESELSKARKTVKDLALQIEESNSQVKARVRDVETLKKSSK--REG 118

Query: 1785 HPIALKGDEDP-LYNEVMRELEKEKHELSNLKTNMASLLXXXXXXXXXXETLDGKAQYHM 1609
              + +K  E    Y E+ +ELE  K ELS LK +MAS+L          E+   K   ++
Sbjct: 119  KGLDIKSSESHHQYAEMKKELELVKEELSKLKLDMASVLEEKSRAEKEIESSSSKLLPNL 178

Query: 1608 NLVKALTNEVEKCNEEHVLVELARLEAAKERKDIESQRQEAEQKHSARMEETRKKINSMI 1429
            + V AL  E+E+ NEEHVL ELAR+EA KE ++I++QR+E   + S  ME+TR+K+    
Sbjct: 179  SSVDALRKEIEEVNEEHVLAELARIEALKEFEEIQAQREEEASEFSIEMEKTREKMKVAN 238

Query: 1428 KETRHIEELQRLLGLTSSEANVLGKELNEFREIDKRIQRVQP--------------SYXX 1291
            +E  H +ELQ  L +T ++ +VL  EL   +EI+K++ R                     
Sbjct: 239  EEIDHSKELQSKLAVTLTDVDVLQNELKVVKEIEKKVLRNDSLKHSGGSFQRSNELEDSR 298

Query: 1290 XXXXXXXXXEAAKKKLDSRKAESIQLMDSMDSLRNKIKAIMEESERLSKKEAKTELTMQN 1111
                     EAAK++L S K E  Q M SMD +RN++K + EE+  L KKE K ELT+QN
Sbjct: 299  PLSSIAEELEAAKEELSSVKEEGFQFMASMDIIRNELKHVTEETAELEKKEQKAELTVQN 358

Query: 1110 LNSKLLRGKAKIEAVSASREKAELIVSNLSTTLEKYESEAEAFENDRIVTTEKAAAYKSE 931
            L SKLLR K+K+E  + + EKA+ IVSNLS T ++ ++EAE    ++ + +E+ A  K+E
Sbjct: 359  LKSKLLRAKSKLENATEAEEKAKSIVSNLSVTRDQLKTEAEVAGKEKKLISEETANVKAE 418

Query: 930  VESIESEIDLAEEKFQAALEELKSVRSSEAKSLQNLKSLTQKTMQDRASASLHSSTITIS 751
            ++  ESEID  EE+ QAA++EL++V++SEA +L +L++LT+  M+ R  AS  +S+ITIS
Sbjct: 419  IQKTESEIDATEERLQAAMQELEAVKASEASALDSLQNLTENAMRIRDFASQQTSSITIS 478

Query: 750  AFEYEYLTGSAERXXXXXXXXXXXXXAWVEALKTSEKEILMKTKSAQNGI-ESREKENQG 574
             FEYEYLTG A R             AWVEALK SEKE+LM+ + A   I E+R +E Q 
Sbjct: 479  KFEYEYLTGRAVRAEEIADKKVAAAQAWVEALKASEKEVLMRIEMAHREIRETRVEEEQE 538

Query: 573  VTRTDQLLSGNNNFEPHIEN------SRPNAENME--------EFNNQLTMSRKSITGKM 436
            V RT++ +S     E  I N       +   EN++        + NN  +  RKS+ G  
Sbjct: 539  VYRTERSMSAKRAVEGEIRNWRQKQQKKTQTENLQSQTPRKSIQNNNGNSSPRKSMKGNS 598

Query: 435  KLIQARQGNLQKSISPAVRARP--ASFSIKRRPKVMPNLAKFLSGK 304
                +++G ++ S SPA+R  P   SF I+++ KVMP+L K   GK
Sbjct: 599  NWTPSKRGRVRNSASPAIRTTPGSTSFIIRKKKKVMPDLVKLFGGK 644


>ref|XP_003551836.1| PREDICTED: protein PLASTID MOVEMENT IMPAIRED 2-like [Glycine max]
          Length = 615

 Score =  371 bits (953), Expect = e-100
 Identities = 235/615 (38%), Positives = 348/615 (56%), Gaps = 15/615 (2%)
 Frame = -2

Query: 2103 QEIGSVKAAIDFYKGKMPMKQQSNYSEKQPPSKTGELHRARRKSGLLQDARGVADSVKSQ 1924
            + +GSV AA++FY             +K+P S+T ELHRARR  G  ++++  A+S K+Q
Sbjct: 9    KRVGSVNAAVNFY------------DDKKPSSRTKELHRARRDIGRYKESKWTAESAKAQ 56

Query: 1923 AERELLSAXXXXXXXXXXXXESNLSAKAQIEAMEKLQKTKRGARRNHPIALKGDEDPLYN 1744
            AE EL +A            ESN  AK Q+  +E+L+K  +G      +A K +E+  Y 
Sbjct: 57   AESELSNAKKTANHLSSMLEESNYKAKTQMRDVERLEKWGKGQHGTIVVA-KRNENFEYA 115

Query: 1743 EVMRELEKEKHELSNLKTNMASLLXXXXXXXXXXETLDGKAQYHMNLVKALTNEVEKCNE 1564
            +VMRELE  K EL  LK ++A ++          E  + K    +   + L  E+E+ NE
Sbjct: 116  QVMRELEYLKKELFKLKLDVAYVMEQKSRAEKEIEASNSKMLSCLTTAEELRREIEEANE 175

Query: 1563 EHVLVELARLEAAKERKDIESQRQEAEQKHSARMEETRKKINSMIKETRHIEELQRLLGL 1384
            E VL ELAR+EA+KE  DIE+QR++   + S ++E TR+K+   I+E    +EL+  L +
Sbjct: 176  EQVLAELARIEASKELTDIETQRKQEANEFSFKLESTRRKLKEAIEEIDESKELEMKLAV 235

Query: 1383 TSSEANVLGKELNEFREIDKRIQR--------------VQPSYXXXXXXXXXXXEAAKKK 1246
            T S+ + L  EL   +E+DKR+Q                +              EAA+K+
Sbjct: 236  TISDVDFLQNELKSVKEMDKRVQGDGSAKQLEGRFKKGEESEDSIVLQTITEELEAARKE 295

Query: 1245 LDSRKAESIQLMDSMDSLRNKIKAIMEESERLSKKEAKTELTMQNLNSKLLRGKAKIEAV 1066
            L   + E  Q M S+D +RN++K +  E++RL KKE K + T+QNLN K+LR K+K+EAV
Sbjct: 296  LALVREEGFQFMASLDVIRNELKHVTAETDRLKKKEGKVDSTVQNLNFKILRAKSKLEAV 355

Query: 1065 SASREKAELIVSNLSTTLEKYESEAEAFENDRIVTTEKAAAYKSEVESIESEIDLAEEKF 886
            SA+ EKA  IV +LS TLEK ++E E  + +    +++ AA K E++ +E +ID  EE+ 
Sbjct: 356  SAAEEKARSIVMSLSHTLEKLKTETEEAKKENEDVSQEVAATKEEIQKVELDIDTTEERL 415

Query: 885  QAALEELKSVRSSEAKSLQNLKSLTQKTMQDRASASLHSSTITISAFEYEYLTGSAERXX 706
            Q  ++EL+  ++SEA +L+ LK+LT++TM++RA  + HSS ITIS FEYEYLT  A    
Sbjct: 416  QGVMQELEVAKASEALALEKLKTLTERTMRERALTAQHSSMITISKFEYEYLTNHAASAE 475

Query: 705  XXXXXXXXXXXAWVEALKTSEKEILMKTKSAQNGI-ESREKENQGVTRTDQLLSGNNNFE 529
                       AW+EALK SEKEILM+TK AQ  + ES+ ++   V   +++LS   +  
Sbjct: 476  EIADKKVAAAEAWIEALKASEKEILMETKIAQRELKESKLEQELEVYTKEKMLSRRVSSS 535

Query: 528  PHIENSRPNAENMEEFNNQLTMSRKSITGKMKLIQARQGNLQKSISPAVRARPASFSIKR 349
              ++N     E     N Q  +SRKSI     +  AR    QK+ SPA R   + F+IK+
Sbjct: 536  EELDNWPRKREKTSSKNFQRALSRKSIKLNGTITPARGAKFQKTASPAAR-HISPFTIKK 594

Query: 348  RPKVMPNLAKFLSGK 304
            R KV+PNL K   GK
Sbjct: 595  RKKVIPNLTKLFRGK 609


>ref|XP_002281016.2| PREDICTED: protein PLASTID MOVEMENT IMPAIRED 2-like [Vitis vinifera]
          Length = 639

 Score =  370 bits (949), Expect = 1e-99
 Identities = 248/637 (38%), Positives = 363/637 (56%), Gaps = 28/637 (4%)
 Frame = -2

Query: 2130 MSTGGYEERQEIGSVKAAIDFY-----KGKMPMKQQSNYSEKQPPSKTGELHRARRKSGL 1966
            M  G    R+ IGS KA I+ Y     +G   +++      ++P S   EL  ARR  G 
Sbjct: 1    MERGENNSRRRIGSFKADINMYGERNLEGSAALRKPHLEILEKPSSIARELLLARRDIGR 60

Query: 1965 LQDARGVADSVKSQAERELLSAXXXXXXXXXXXXESNLSAKAQ-IEAMEKLQKTKRGARR 1789
              ++R  ADS+K +AE EL +A            ES   AK Q +E ++K +K + G   
Sbjct: 61   FSESRRAADSMKIEAESELFNAKKTVRTLSSLINESKAKAKMQDLEDIKKPEKREEGRAS 120

Query: 1788 NHPIALKGDEDPLYNEVMRELEKEKHELSNLKTNMASLLXXXXXXXXXXETLDGKAQYHM 1609
            +   A    E+  Y EVM+E+E  K ELS LK +MAS+L          E    K   + 
Sbjct: 121  DVGKA----ENYQYAEVMKEVELMKQELSKLKLDMASVLEEKSRAEKEIEAASSKIWSYG 176

Query: 1608 NLVKALTNEVEKCNEEHVLVELARLEAAKERKDIESQRQEAEQKHSARMEETRKKINSMI 1429
            +   +L  E+E+ NE+ VLVELAR+EA KE   IE+QR++   + S+ ME+TRKK++ +I
Sbjct: 177  SSANSLKKEIEEANEDQVLVELARIEAVKELVAIEAQREKEANEFSSAMEKTRKKMSDII 236

Query: 1428 KETRHIEELQRLLGLTSSEANVLGKELNEFREIDKRIQR------VQPSYXXXXXXXXXX 1267
            +E    ++L+  L +T+S+ +VL  EL   ++IDK +Q        + S+          
Sbjct: 237  QEIEQSKDLETKLSVTTSDIDVLQNELKLAKKIDKSVQNNDSLKHTKGSFRRQEGSETSA 296

Query: 1266 XE--------AAKKKLDSRKAESIQLMDSMDSLRNKIKAIMEESERLSKKEAKTELTMQN 1111
                      AAKK+L S K E    M SMD +R ++K + EE+ RL K E K++LT++N
Sbjct: 297  LLQSVTEELKAAKKELASIKEEGFDFMSSMDVIREELKHVTEETARLKKTEEKSDLTVKN 356

Query: 1110 LNSKLLRGKAKIEAVSASREKAELIVSNLSTTLEKYESEAEAFENDRIVTTEKAAAYKSE 931
            LN KLLR ++K+EA S + E A  I SNL+ TLE+ +++AEA + +R + +E+ A   +E
Sbjct: 357  LNLKLLRAQSKLEATSKAEENARSIASNLTLTLEQLKTDAEAVKKERELISEETATINAE 416

Query: 930  VESIESEIDLAEEKFQAALEELKSVRSSEAKSLQNLKSLTQKTMQDRASASLHSSTITIS 751
            ++  +SEIDL EE+ Q+A++EL++V+SSEA +L+ L+++T+ TM+ RASAS  +S+I IS
Sbjct: 417  IQKTDSEIDLNEERLQSAMQELEAVKSSEAIALEKLQTVTEITMRARASASQQNSSIFIS 476

Query: 750  AFEYEYLTGSAERXXXXXXXXXXXXXAWVEALKTSEKEILMKTKSAQNGI-ESREKENQG 574
             FEYEYLTG A               AW+EALK SEKEILM+T+ AQ  I E R +E + 
Sbjct: 477  KFEYEYLTGHAVGAEEVADKMVAAAQAWIEALKASEKEILMQTEVAQREIRELRMEEEKQ 536

Query: 573  VTRTDQLLSGNNNFEPHIENSR-----PNAENMEEFNNQLTMSRKSITGKMKLIQARQGN 409
            V R ++ LS     E  I+NSR           E    QL + +KSI  K  L  AR+  
Sbjct: 537  VLRMERSLSATKAVEGEIQNSRLKRQMSRGRRTENMQLQLALPKKSIKDKGNLTPARRAK 596

Query: 408  LQKSISPAVR--ARPASFSIKRRPKVMPNLAKFLSGK 304
            L+KS SPA+R   R +S ++K+R KVMP+LAKF   K
Sbjct: 597  LRKSDSPAIRHFPRSSSVNLKKRKKVMPSLAKFFRSK 633


>ref|XP_003520017.1| PREDICTED: protein PLASTID MOVEMENT IMPAIRED 2-like [Glycine max]
          Length = 620

 Score =  366 bits (940), Expect = 1e-98
 Identities = 238/629 (37%), Positives = 354/629 (56%), Gaps = 22/629 (3%)
 Frame = -2

Query: 2103 QEIGSVKAAIDFYKGKMPMKQQSNYSEKQPPSKTGELHRARRKSGLLQDARGVADSVKSQ 1924
            + +GSVKAA++FY             +K+P S+T ELHRARR  G  ++++  A+SV +Q
Sbjct: 9    KRVGSVKAAVNFY------------DDKKPSSRTRELHRARRDIGRYKESKWTAESVTAQ 56

Query: 1923 AERELLSAXXXXXXXXXXXXESNLSAKAQ---IEAMEKLQKTKRGARRNHPIALKGDEDP 1753
            AE EL +A            ES+  AK Q   +E++EK  K++ GA     +  K +E+ 
Sbjct: 57   AEPELSNAKKTAEHLSSMIEESSYKAKTQMIDVESLEKRGKSQHGAI----VVAKRNENY 112

Query: 1752 LYNEVMRELEKEKHELSNLKTNMASLLXXXXXXXXXXETLDGKAQYHMNLVKALTNEVEK 1573
             Y +VMRELE  K EL  LK ++AS++          E  + K    +   + L  E+E+
Sbjct: 113  EYAQVMRELEYLKKELFKLKLDVASVMDQKSRAEKEIEASNSKMLSCLTTAEELRREIEE 172

Query: 1572 CNEEHVLVELARLEAAKERKDIESQRQEAEQKHSARMEETRKKINSMIKETRHIEELQRL 1393
             NEE VL ELAR+EA+KE  DIE+QR++   + S  +E  R+K+   I+E    +EL+  
Sbjct: 173  ANEEQVLAELARIEASKELADIEAQREKEANQFSFNLEIARRKLKEAIEEIDESKELEMK 232

Query: 1392 LGLTSSEANVLGKELNEFREIDKRIQR--------------VQPSYXXXXXXXXXXXEAA 1255
            L +T S+ + L  EL   ++++KR+Q                +  Y           EAA
Sbjct: 233  LAVTISDVDFLQNELKSVKDMNKRVQGDGSVKQLEGIFRKGEESEYSIVLQTITEELEAA 292

Query: 1254 KKKLDSRKAESIQLMDSMDSLRNKIKAIMEESERLSKKEAKTELTMQNLNSKLLRGKAKI 1075
            +K+L   + E  Q M SMD +RN++K +  E++RL KKE K + T+QNLNSK+LR K+K+
Sbjct: 293  RKELALVREEGFQFMASMDVIRNELKHVTAETDRLKKKEGKVDSTVQNLNSKILRAKSKL 352

Query: 1074 EAVSASREKAELIVSNLSTTLEKYESEAEAFENDRIVTTEKAAAYKSEVESIESEIDLAE 895
            EAVSA+ EK   IV +LS TLEK ++E    + +    +++ AA K E++ +E EID+ E
Sbjct: 353  EAVSAAEEKVRSIVMSLSHTLEKLKTETADAKKENEDVSQEVAASKEEIQKVEFEIDMTE 412

Query: 894  EKFQAALEELKSVRSSEAKSLQNLKSLTQKTMQDRASASLHSSTITISAFEYEYLTGSAE 715
            E+ Q  ++EL+  ++SEA +L+ LK+LT+ TM++RA  + HSS ITIS FEYEYLT  A 
Sbjct: 413  ERLQGIMQELEVAKASEALALEKLKTLTETTMRERALTTQHSSMITISKFEYEYLTNHAA 472

Query: 714  RXXXXXXXXXXXXXAWVEALKTSEKEILMKTKSAQNGI-ESREKENQGVTRTDQLLSGN- 541
                          AW+EALK SEKEILM+TK AQ  + E++ ++ Q V   +++LS   
Sbjct: 473  SAQEIADKKVAAAEAWIEALKASEKEILMETKIAQRELKETKLEQEQEVYTKEKMLSRRV 532

Query: 540  NNFEPHIENSRPNAENMEEFNNQLTMSRKSITGKMKLIQARQGNLQKSISPAVRARPASF 361
             +     +N     E     N Q  MSRKSI     +  AR    QK+ SPA R   + F
Sbjct: 533  VSSSEEFDNWPRKREKSSSKNFQRAMSRKSIKLNGTITPARGAKFQKTASPAAR-HISPF 591

Query: 360  SIKRRPKVMPNLAKFLSGK---GVHENLQ 283
            +IK+R KV+PNL K   G+   G+H  ++
Sbjct: 592  TIKKRKKVIPNLTKLFRGRKTLGIHSEIK 620


>ref|XP_002303000.1| predicted protein [Populus trichocarpa] gi|222844726|gb|EEE82273.1|
            predicted protein [Populus trichocarpa]
          Length = 642

 Score =  366 bits (939), Expect = 2e-98
 Identities = 236/640 (36%), Positives = 360/640 (56%), Gaps = 31/640 (4%)
 Frame = -2

Query: 2115 YEERQEIGSVKAAIDFYKGKMPMKQQSNYSEKQPP---------SKTGELHRARRKSGLL 1963
            +++R+ IG+VKAA++ Y  ++   + S+ S K P          S+  ELH A+R     
Sbjct: 6    FDDRRRIGTVKAAVNMYGERI--LESSSSSLKTPAQMDLPEKSSSRAKELHMAKRDLVRY 63

Query: 1962 QDARGVADSVKSQAERELLSAXXXXXXXXXXXXESNLSAKAQIEAMEKLQKTKRGARRNH 1783
            ++ R  A+S K +AE EL  A            +SNL  KAQ+  ME+L K  +  R++ 
Sbjct: 64   KENRRAAESAKVKAESELSEAKRTVKELVLQIEKSNLKVKAQVRDMERLNKLSK--RQDM 121

Query: 1782 PIALKGDEDPLYNEVMRELEKEKHELSNLKTNMASLLXXXXXXXXXXETLDGKAQYHMNL 1603
             + +  DE   Y EV+RELE  K ELS LK  MAS+L           T   K   +M+ 
Sbjct: 122  ALIVGSDESHQYAEVIRELEGVKQELSKLKLEMASVLEAKTRAEKEIATSISKLSSNMSH 181

Query: 1602 VKALTNEVEKCNEEHVLVELARLEAAKERKDIESQRQEAEQKHSARMEETRKKINSMIKE 1423
             +AL  ++++ NEE VLVELA++EA KE  +I++QR++  ++ S+ M+ET+ K  ++ +E
Sbjct: 182  AEALRKKIDEANEEQVLVELAQIEALKEFGEIQAQREKEAREFSSAMQETKNKRKNVKEE 241

Query: 1422 TRHIEELQRLLGLTSSEANVLGKELNEFREIDKRIQR--------------VQPSYXXXX 1285
                 +L+  L +T  + N++  EL   ++ D ++QR               Q       
Sbjct: 242  ISSSTDLESKLAVTLYDVNLIQHELKLAKDKDAKVQRNDSMKHLGGSFREGKQLEDSSLL 301

Query: 1284 XXXXXXXEAAKKKLDSRKAESIQLMDSMDSLRNKIKAIMEESERLSKKEAKTELTMQNLN 1105
                   +AAKK+L S + E  Q M SMD +RN++K + EE+ +L K + K ++T QNLN
Sbjct: 302  KSITEELQAAKKELASTREEGFQFMTSMDIVRNELKHVTEETVQLKKVKEKADITAQNLN 361

Query: 1104 SKLLRGKAKIEAVSASREKAELIVSNLSTTLEKYESEAEAFENDRIVTTEKAAAYKSEVE 925
            SKLLR K+K+E  +A  EKA   +S+LS TLE+ ++EAE    ++ +  E+ A  K+E+ 
Sbjct: 362  SKLLRAKSKLETATAVEEKARSTLSSLSVTLEQLKTEAEVARKEKKLICEETAKIKAEIR 421

Query: 924  SIESEIDLAEEKFQAALEELKSVRSSEAKSLQNLKSLTQKTMQDRASASLHSSTITISAF 745
            + +S+IDL EEK Q A++EL +V+ SE+ +LQNLK++ + TM+ RASAS HSS+ITIS F
Sbjct: 422  NTDSQIDLTEEKLQYAIQELDAVKKSESSALQNLKNVIENTMRSRASASQHSSSITISKF 481

Query: 744  EYEYLTGSAERXXXXXXXXXXXXXAWVEALKTSEKEILMKTKSAQNGI-ESREKENQGVT 568
            EYEYLTG A               AW+EALK SEKEILMK + A   I E+R +E + + 
Sbjct: 482  EYEYLTGHAAMAEEIADKKVAAAHAWIEALKASEKEILMKIELAHGDIRETRVEEEKEIY 541

Query: 567  RTDQLLSGNNNFEPHIENSRP-NAENMEEFNNQLTMSRKSITGKMKLIQARQGNLQKSIS 391
            RT+  LS     E  +   R  + +N E  N Q  + RKS+     L  +R+  L+ + S
Sbjct: 542  RTESSLSAKRMVEGELPKWRQVSKKNTEAENQQQPLPRKSMKANGNLTLSRRSKLRNAGS 601

Query: 390  PAVRARP------ASFSIKRRPKVMPNLAKFLSGKGVHEN 289
            P+VR  P       S +I+++  ++PNLAK   GK V ++
Sbjct: 602  PSVRMTPRITPRSTSIAIRKKRTIVPNLAKLFIGKKVDKD 641