BLASTX 2.2.25 [Feb-01-2011]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= Forsythia23_contig00035284
         (3439 letters)

Database: ./nr 
           69,698,275 sequences; 24,982,196,650 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

emb|CDP07797.1| unnamed protein product [Coffea canephora]           1828   0.0  
ref|XP_010241214.1| PREDICTED: DNA topoisomerase 2-like isoform ...  1809   0.0  
ref|XP_010241213.1| PREDICTED: DNA topoisomerase 2-like isoform ...  1809   0.0  
ref|XP_002274267.1| PREDICTED: DNA topoisomerase 2 [Vitis vinifera]  1803   0.0  
ref|XP_012849677.1| PREDICTED: DNA topoisomerase 2 [Erythranthe ...  1784   0.0  
ref|XP_011087923.1| PREDICTED: DNA topoisomerase 2 isoform X2 [S...  1782   0.0  
ref|XP_011087914.1| PREDICTED: DNA topoisomerase 2 isoform X1 [S...  1782   0.0  
ref|XP_007009329.1| Topoisomerase II isoform 3 [Theobroma cacao]...  1778   0.0  
ref|XP_007009327.1| DNA topoisomerase 2 isoform 1 [Theobroma cac...  1778   0.0  
ref|XP_010257162.1| PREDICTED: LOW QUALITY PROTEIN: DNA topoisom...  1773   0.0  
ref|XP_010920068.1| PREDICTED: DNA topoisomerase 2 [Elaeis guine...  1759   0.0  
ref|XP_011621441.1| PREDICTED: DNA topoisomerase 2 [Amborella tr...  1748   0.0  
gb|ERN00852.1| hypothetical protein AMTR_s00103p00101630 [Ambore...  1748   0.0  
ref|XP_010023678.1| PREDICTED: DNA topoisomerase 2-like [Eucalyp...  1746   0.0  
ref|XP_010023597.1| PREDICTED: DNA topoisomerase 2-like [Eucalyp...  1746   0.0  
ref|XP_009800897.1| PREDICTED: LOW QUALITY PROTEIN: DNA topoisom...  1739   0.0  
emb|CBI24922.3| unnamed protein product [Vitis vinifera]             1737   0.0  
ref|XP_008231458.1| PREDICTED: DNA topoisomerase 2 isoform X2 [P...  1736   0.0  
ref|XP_008231457.1| PREDICTED: DNA topoisomerase 2 isoform X1 [P...  1736   0.0  
ref|XP_009630917.1| PREDICTED: LOW QUALITY PROTEIN: DNA topoisom...  1735   0.0  

>emb|CDP07797.1| unnamed protein product [Coffea canephora]
          Length = 1486

 Score = 1828 bits (4736), Expect = 0.0
 Identities = 898/1135 (79%), Positives = 1010/1135 (88%), Gaps = 17/1135 (1%)
 Frame = -1

Query: 3355 KAPLTSSNNANIPPEXXXXXXXXXAKTIEQTYQKKTQLEHILLRPDTYIGSIEKHNQTLW 3176
            K PL SSNNANI             KTIE+TYQKK+QLEHILLRPDTYIGSIEKH+QTLW
Sbjct: 8    KLPLQSSNNANI--------VLPTGKTIEETYQKKSQLEHILLRPDTYIGSIEKHSQTLW 59

Query: 3175 VYEEKQMVQKPITYVPGLYKIFDEILVNAADNKQRDPKMNSLKVTIDAEANCISVYNNGD 2996
            V+E   MV + I+YVPGLYKIFDEILVNAADNKQRDP+M+S+K+ I+ E N ISVYNNGD
Sbjct: 60   VFENDAMVHRQISYVPGLYKIFDEILVNAADNKQRDPRMDSVKIVINVEENFISVYNNGD 119

Query: 2995 GVPVEIHQEEGVYVPELIFGHLLTSSNYDDHEKKTTGGRNGYGAKLTNIFSTEFVIETAD 2816
            GVPVE+HQEEGVYVPELIFGHLLTSSNYDD  KKTTGGRNGYGAKLTNIFSTEFVIE+AD
Sbjct: 120  GVPVEVHQEEGVYVPELIFGHLLTSSNYDDTVKKTTGGRNGYGAKLTNIFSTEFVIESAD 179

Query: 2815 GRRQRKYKQVFTCNMGNKSQPVISKCKESENWTKVTFKPDLSKFNMTHLEDDVVALMKKR 2636
            GRRQ+KYKQVF+ NMGNKSQP+ISKCKESENWTKVT+KPDL+KFNMTHLEDDVVALMKKR
Sbjct: 180  GRRQKKYKQVFSNNMGNKSQPIISKCKESENWTKVTYKPDLAKFNMTHLEDDVVALMKKR 239

Query: 2635 VIDMAGCLGKNVKVELNGEDIRVRSFGDYCNLYLKSAF--------RIEEKV-DRWEVCV 2483
            V+D+AGCLGK VKVELNG+ + V+SF DYC+LYL+SA         RI EKV +RWEVC 
Sbjct: 240  VVDLAGCLGKTVKVELNGQRVPVKSFSDYCDLYLQSAAKTRPDPLPRIVEKVNERWEVCA 299

Query: 2482 SLSDGQFQQVSFVNSISTIKGGTHVDYVTNQIATHLAEYVNKKRKNANLKPHSVRNHLWV 2303
            SLS+GQFQQVSFVN I+TIKGGTHVDYVTNQI  H+   VNKK KNANLK HSV+NHLWV
Sbjct: 300  SLSEGQFQQVSFVNGIATIKGGTHVDYVTNQITNHIIGIVNKKNKNANLKAHSVKNHLWV 359

Query: 2302 FVNCLIDNPAFDSQTKETLTLRQKSFGSECKLSDKFLSKVANSEIVNNILEWAEFKEKKD 2123
            FVN LIDNPAFDSQTKETLTLRQ SFGS+C+LS +FL KVA S +V N+L WA+FK+ KD
Sbjct: 360  FVNALIDNPAFDSQTKETLTLRQSSFGSKCELSQEFLKKVAKSGVVENLLSWADFKQSKD 419

Query: 2122 LKKTDGTKSKRITGLTKLADANNAGGRNSEKCTLILTEGDSAATLAIAGLSVVGRDHYGV 1943
            LKKTDGTK +RITG+TKL DAN+AGG+NS++CTLILTEGDSA  LA+AG+SVVGR+ YGV
Sbjct: 420  LKKTDGTKRQRITGITKLEDANDAGGKNSDRCTLILTEGDSAKALAMAGISVVGRNFYGV 479

Query: 1942 FPLRGKLLNVRDASTKQINDNAEIQNIKKILGLQHGKQYDSIKSLRYGHLMIMTDQDHDG 1763
            FPLRGKLLNVR+AS KQI DNAEIQ IK+ILGLQHGK YDS+KSLRYGHLMIMTDQDHDG
Sbjct: 480  FPLRGKLLNVREASHKQIMDNAEIQYIKQILGLQHGKVYDSVKSLRYGHLMIMTDQDHDG 539

Query: 1762 SHIKGLLINFIHSFWPSLLRIPSFLVEFITPIVKATHKNGEKRSFYTMPEYESWKESLGD 1583
            SHIKGLLINFIHSFWPSLL+IPSFLVEFITPIVKATHKNG   SFYTMPEYESWKESL  
Sbjct: 540  SHIKGLLINFIHSFWPSLLKIPSFLVEFITPIVKATHKNGRVLSFYTMPEYESWKESLSG 599

Query: 1582 KARSWSIKYYKGLGTSTDKEGKEYFKDLGKHKKDFVWADDHDGEAIELAFSKKKIEARKN 1403
             A  WSIKYYKGLGTST KEGKEYFKDLGKHKKDF+W DD+DGEAIELAFSKKKIEARKN
Sbjct: 600  NATGWSIKYYKGLGTSTSKEGKEYFKDLGKHKKDFIWVDDNDGEAIELAFSKKKIEARKN 659

Query: 1402 WLRQFEPGTYLDQEDKLIKYRDFVNKELILFSIADLQRSIPSMVDGLKPGQRKILFCAFK 1223
            WLRQFEPGTYLDQ++KLIKY DF+NKELILFS+ADLQRSIPSMVDGLKPGQRKILFC+FK
Sbjct: 660  WLRQFEPGTYLDQKEKLIKYSDFINKELILFSLADLQRSIPSMVDGLKPGQRKILFCSFK 719

Query: 1222 RNFVHEAKVGQFAGYVSEHSAYHHGEQSLASTIIGMAQQYVGSNNINILKPNGQFGTRNQ 1043
            RNFV EAKV QF+GYVSEHSAYHHGEQSLAS IIGMAQ +VGSNNIN+L+PNGQFGTRNQ
Sbjct: 720  RNFVKEAKVAQFSGYVSEHSAYHHGEQSLASAIIGMAQDFVGSNNINLLQPNGQFGTRNQ 779

Query: 1042 GGKDHASARYIFTQLSAITRFLFPKDDDILLDYQNEDGQTIEPTWYVPIIPVVLVNGSEG 863
            GGKDHASARY++T+LS ITR LFPKDDDILLDY NEDGQ+IEPTWY+PIIP+VLVNGSEG
Sbjct: 780  GGKDHASARYVYTRLSPITRSLFPKDDDILLDYLNEDGQSIEPTWYMPIIPMVLVNGSEG 839

Query: 862  IGTGWSSFVPNYNPRDIIANVRHMLRDEPMEPMDPWYKGFRGTIEKTATKEAGATYTVTG 683
            IGTGWSS++PNYNPRDII N+R +L +EPMEPM+PWYKGFRGTIEKTATKEAGA+YTV+G
Sbjct: 840  IGTGWSSYIPNYNPRDIIGNIRRLLNNEPMEPMEPWYKGFRGTIEKTATKEAGASYTVSG 899

Query: 682  IIEEVSDTTLRVTELPVRKWTQDYKDFLESLY--------PFIEDVREYHTTDSVNFEID 527
            I+EEV +TT+RVTELPVRKWTQDYK+FLES+         PFI++ R++    +V  +I 
Sbjct: 900  IVEEVDETTIRVTELPVRKWTQDYKEFLESIMMGNEKVKDPFIKEFRDHTDDTTVYLDII 959

Query: 526  LSEENMRIAKQEGLLKKFKLTTTISTSNMHLFDSKGVIKKYDTPEKILEDFFSIRFEFYE 347
            +SEEN+ +AKQEGLLKKFKLTTTISTSNMHLFDS+G+IKK+D PE+ILE+FF +R EFYE
Sbjct: 960  MSEENLLMAKQEGLLKKFKLTTTISTSNMHLFDSQGIIKKFDNPEQILEEFFHLRLEFYE 1019

Query: 346  KRKKALMDNLERELLILENKVRFIMDVVEGKIVVSNRRRADLVLELKEKGFTPFPKKAKT 167
            KRKK L+DNL+ ELL L+NKVRFI+ VVEG I+VSNR+RADL LELKEKGFTPFPKK K+
Sbjct: 1020 KRKKVLLDNLQLELLKLDNKVRFILAVVEGSIIVSNRKRADLFLELKEKGFTPFPKK-KS 1078

Query: 166  TEISVAGSTDVPEETEENSDMATSQGVRASDYEYLLSMSIGSLTIEKVQELCNNR 2
             E +VAGS +  EETEE+S++ATS+GVRASDYEYL+SM+IGSLT+EKVQELC +R
Sbjct: 1079 VEAAVAGSIEDAEETEESSEVATSKGVRASDYEYLISMAIGSLTLEKVQELCADR 1133


>ref|XP_010241214.1| PREDICTED: DNA topoisomerase 2-like isoform X2 [Nelumbo nucifera]
          Length = 1503

 Score = 1809 bits (4685), Expect = 0.0
 Identities = 884/1136 (77%), Positives = 1003/1136 (88%), Gaps = 17/1136 (1%)
 Frame = -1

Query: 3358 KKAPLTSSNNANIPPEXXXXXXXXXAKTIEQTYQKKTQLEHILLRPDTYIGSIEKHNQTL 3179
            +K PL +SN AN+P            KTIE+TYQKK+QLEHILLRPDTY+GSIEKH QTL
Sbjct: 5    RKLPLQTSNIANVPSSRPLVGSG---KTIEETYQKKSQLEHILLRPDTYVGSIEKHTQTL 61

Query: 3178 WVYEEKQMVQKPITYVPGLYKIFDEILVNAADNKQRDPKMNSLKVTIDAEANCISVYNNG 2999
            WVY+  +MV +P+TYVPGLYKIFDEILVNAADNKQRDP M+S+KV IDAE NCISVYNNG
Sbjct: 62   WVYDGGEMVHRPVTYVPGLYKIFDEILVNAADNKQRDPSMDSVKVVIDAEQNCISVYNNG 121

Query: 2998 DGVPVEIHQEEGVYVPELIFGHLLTSSNYDDHEKKTTGGRNGYGAKLTNIFSTEFVIETA 2819
            DGVPVEIHQEEGVYVPELIFGHLLTSSNYDD  KKTTGGRNGYGAKLTNIFSTEF+IETA
Sbjct: 122  DGVPVEIHQEEGVYVPELIFGHLLTSSNYDDTVKKTTGGRNGYGAKLTNIFSTEFIIETA 181

Query: 2818 DGRRQRKYKQVFTCNMGNKSQPVISKCKESENWTKVTFKPDLSKFNMTHLEDDVVALMKK 2639
            DG+RQ+KYKQVF+ NMG KS+P I+KCK SENWTKVTFKPDL+KFN+THLEDDVVALMKK
Sbjct: 182  DGKRQKKYKQVFSNNMGKKSEPAITKCKGSENWTKVTFKPDLAKFNLTHLEDDVVALMKK 241

Query: 2638 RVIDMAGCLGKNVKVELNGEDIRVRSFGDYCNLYLKSAF--------RIEEKV-DRWEVC 2486
            RVID+AGCLGK VKVELNG+ + V+SF DY NLYL+SA         RI EKV +RWEVC
Sbjct: 242  RVIDLAGCLGKTVKVELNGQRVPVKSFLDYVNLYLQSASKSRPEPLPRITEKVSERWEVC 301

Query: 2485 VSLSDGQFQQVSFVNSISTIKGGTHVDYVTNQIATHLAEYVNKKRKNANLKPHSVRNHLW 2306
            VSLS+GQFQQVSFVN I+TIKGGTHVDYVTNQI  H+   VNKK KNANLK H+V+NHLW
Sbjct: 302  VSLSEGQFQQVSFVNGIATIKGGTHVDYVTNQITNHVMTIVNKKNKNANLKAHTVKNHLW 361

Query: 2305 VFVNCLIDNPAFDSQTKETLTLRQKSFGSECKLSDKFLSKVANSEIVNNILEWAEFKEKK 2126
            VFVN LIDNPAFDSQTKETLT RQ SFGS+C+LS +FL KVA S +V N+L WA+FK+ K
Sbjct: 362  VFVNSLIDNPAFDSQTKETLTTRQSSFGSKCELSQEFLKKVAKSGVVENLLSWADFKQSK 421

Query: 2125 DLKKTDGTKSKRITGLTKLADANNAGGRNSEKCTLILTEGDSAATLAIAGLSVVGRDHYG 1946
            DLKKTDG K +RITG+TKL DAN+AGGRNSEKCTLILTEGDSA  LA+AG+SVVGR++YG
Sbjct: 422  DLKKTDGAKRQRITGITKLEDANDAGGRNSEKCTLILTEGDSAKALAMAGISVVGRNNYG 481

Query: 1945 VFPLRGKLLNVRDASTKQINDNAEIQNIKKILGLQHGKQYDSIKSLRYGHLMIMTDQDHD 1766
            VFPLRGKLLNVR+A+ KQI DNAEIQNIK+ILGLQHGK+YDS+KSLRYGHLMIMTDQDHD
Sbjct: 482  VFPLRGKLLNVREATHKQIMDNAEIQNIKQILGLQHGKEYDSVKSLRYGHLMIMTDQDHD 541

Query: 1765 GSHIKGLLINFIHSFWPSLLRIPSFLVEFITPIVKATHKNGEKRSFYTMPEYESWKESLG 1586
            GSHIKGLLINFIHSFWPSLL+IPSFLVEFITPIVKATHKNG+  SFY+MPEYESWK  LG
Sbjct: 542  GSHIKGLLINFIHSFWPSLLKIPSFLVEFITPIVKATHKNGKVLSFYSMPEYESWKX-LG 600

Query: 1585 DKARSWSIKYYKGLGTSTDKEGKEYFKDLGKHKKDFVWADDHDGEAIELAFSKKKIEARK 1406
              A  WSIKYYKGLGTST KEGKEYFKDL KHKKDF+W DD DG+AIELAFSKKKIEARK
Sbjct: 601  GNASGWSIKYYKGLGTSTSKEGKEYFKDLHKHKKDFLWVDDRDGDAIELAFSKKKIEARK 660

Query: 1405 NWLRQFEPGTYLDQEDKLIKYRDFVNKELILFSIADLQRSIPSMVDGLKPGQRKILFCAF 1226
            NWLRQFEPGT LDQ++KLIKY DFVNKELILFS+ADLQRSIPSMVDGLKPGQRKILFCAF
Sbjct: 661  NWLRQFEPGTCLDQKEKLIKYSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKILFCAF 720

Query: 1225 KRNFVHEAKVGQFAGYVSEHSAYHHGEQSLASTIIGMAQQYVGSNNINILKPNGQFGTRN 1046
            KRN + EAKV QF+GYVSEHSAYHHGEQSL STIIGMAQ YVGSNNIN+ +PNGQFGTR+
Sbjct: 721  KRNLIKEAKVAQFSGYVSEHSAYHHGEQSLMSTIIGMAQDYVGSNNINLFQPNGQFGTRH 780

Query: 1045 QGGKDHASARYIFTQLSAITRFLFPKDDDILLDYQNEDGQTIEPTWYVPIIPVVLVNGSE 866
            QGGKDHASARYI+T+LS ITRFLFPK DDILLDY NEDGQ+IEPTWY+PIIP VLVNGSE
Sbjct: 781  QGGKDHASARYIYTRLSPITRFLFPKGDDILLDYLNEDGQSIEPTWYMPIIPTVLVNGSE 840

Query: 865  GIGTGWSSFVPNYNPRDIIANVRHMLRDEPMEPMDPWYKGFRGTIEKTATKEAGATYTVT 686
            GIGTGWSS++PNYNPRDI+AN++ +L  EPMEPMDPWYKGF+G IEKTATKEAG++YTV+
Sbjct: 841  GIGTGWSSYIPNYNPRDIVANIKRLLNGEPMEPMDPWYKGFKGLIEKTATKEAGSSYTVS 900

Query: 685  GIIEEVSDTTLRVTELPVRKWTQDYKDFLESLY--------PFIEDVREYHTTDSVNFEI 530
            GIIEE+++TTLR+TELP+R+WTQDYK+FLES+         PFI+D +E++   +V+FEI
Sbjct: 901  GIIEEINETTLRITELPIRRWTQDYKEFLESIMTGNDKIKEPFIKDYKEHNDDTTVHFEI 960

Query: 529  DLSEENMRIAKQEGLLKKFKLTTTISTSNMHLFDSKGVIKKYDTPEKILEDFFSIRFEFY 350
             LSEEN+ +AKQEGL+KKFKLTTTISTSNMHLFD KG IKKYD PE+ILE+FF +R EFY
Sbjct: 961  ILSEENLMMAKQEGLMKKFKLTTTISTSNMHLFDPKGTIKKYDNPEQILEEFFHLRLEFY 1020

Query: 349  EKRKKALMDNLERELLILENKVRFIMDVVEGKIVVSNRRRADLVLELKEKGFTPFPKKAK 170
            EKRKK  +DNLE +LL L+NKVRFI+ VV+G+I+VSNR+R DL LEL++KGFTPFPKK K
Sbjct: 1021 EKRKKTQLDNLELDLLKLDNKVRFILGVVKGEIIVSNRKRVDLFLELQQKGFTPFPKKTK 1080

Query: 169  TTEISVAGSTDVPEETEENSDMATSQGVRASDYEYLLSMSIGSLTIEKVQELCNNR 2
              E +VAG+ +  EE EENS++ +S+GVRASDYEYLLSM+IG+LT+EKVQELC++R
Sbjct: 1081 ALEAAVAGANEDGEENEENSEVVSSRGVRASDYEYLLSMAIGTLTLEKVQELCSDR 1136


>ref|XP_010241213.1| PREDICTED: DNA topoisomerase 2-like isoform X1 [Nelumbo nucifera]
          Length = 1504

 Score = 1809 bits (4685), Expect = 0.0
 Identities = 884/1136 (77%), Positives = 1003/1136 (88%), Gaps = 17/1136 (1%)
 Frame = -1

Query: 3358 KKAPLTSSNNANIPPEXXXXXXXXXAKTIEQTYQKKTQLEHILLRPDTYIGSIEKHNQTL 3179
            +K PL +SN AN+P            KTIE+TYQKK+QLEHILLRPDTY+GSIEKH QTL
Sbjct: 5    RKLPLQTSNIANVPSSRPLVGSG---KTIEETYQKKSQLEHILLRPDTYVGSIEKHTQTL 61

Query: 3178 WVYEEKQMVQKPITYVPGLYKIFDEILVNAADNKQRDPKMNSLKVTIDAEANCISVYNNG 2999
            WVY+  +MV +P+TYVPGLYKIFDEILVNAADNKQRDP M+S+KV IDAE NCISVYNNG
Sbjct: 62   WVYDGGEMVHRPVTYVPGLYKIFDEILVNAADNKQRDPSMDSVKVVIDAEQNCISVYNNG 121

Query: 2998 DGVPVEIHQEEGVYVPELIFGHLLTSSNYDDHEKKTTGGRNGYGAKLTNIFSTEFVIETA 2819
            DGVPVEIHQEEGVYVPELIFGHLLTSSNYDD  KKTTGGRNGYGAKLTNIFSTEF+IETA
Sbjct: 122  DGVPVEIHQEEGVYVPELIFGHLLTSSNYDDTVKKTTGGRNGYGAKLTNIFSTEFIIETA 181

Query: 2818 DGRRQRKYKQVFTCNMGNKSQPVISKCKESENWTKVTFKPDLSKFNMTHLEDDVVALMKK 2639
            DG+RQ+KYKQVF+ NMG KS+P I+KCK SENWTKVTFKPDL+KFN+THLEDDVVALMKK
Sbjct: 182  DGKRQKKYKQVFSNNMGKKSEPAITKCKGSENWTKVTFKPDLAKFNLTHLEDDVVALMKK 241

Query: 2638 RVIDMAGCLGKNVKVELNGEDIRVRSFGDYCNLYLKSAF--------RIEEKV-DRWEVC 2486
            RVID+AGCLGK VKVELNG+ + V+SF DY NLYL+SA         RI EKV +RWEVC
Sbjct: 242  RVIDLAGCLGKTVKVELNGQRVPVKSFLDYVNLYLQSASKSRPEPLPRITEKVSERWEVC 301

Query: 2485 VSLSDGQFQQVSFVNSISTIKGGTHVDYVTNQIATHLAEYVNKKRKNANLKPHSVRNHLW 2306
            VSLS+GQFQQVSFVN I+TIKGGTHVDYVTNQI  H+   VNKK KNANLK H+V+NHLW
Sbjct: 302  VSLSEGQFQQVSFVNGIATIKGGTHVDYVTNQITNHVMTIVNKKNKNANLKAHTVKNHLW 361

Query: 2305 VFVNCLIDNPAFDSQTKETLTLRQKSFGSECKLSDKFLSKVANSEIVNNILEWAEFKEKK 2126
            VFVN LIDNPAFDSQTKETLT RQ SFGS+C+LS +FL KVA S +V N+L WA+FK+ K
Sbjct: 362  VFVNSLIDNPAFDSQTKETLTTRQSSFGSKCELSQEFLKKVAKSGVVENLLSWADFKQSK 421

Query: 2125 DLKKTDGTKSKRITGLTKLADANNAGGRNSEKCTLILTEGDSAATLAIAGLSVVGRDHYG 1946
            DLKKTDG K +RITG+TKL DAN+AGGRNSEKCTLILTEGDSA  LA+AG+SVVGR++YG
Sbjct: 422  DLKKTDGAKRQRITGITKLEDANDAGGRNSEKCTLILTEGDSAKALAMAGISVVGRNNYG 481

Query: 1945 VFPLRGKLLNVRDASTKQINDNAEIQNIKKILGLQHGKQYDSIKSLRYGHLMIMTDQDHD 1766
            VFPLRGKLLNVR+A+ KQI DNAEIQNIK+ILGLQHGK+YDS+KSLRYGHLMIMTDQDHD
Sbjct: 482  VFPLRGKLLNVREATHKQIMDNAEIQNIKQILGLQHGKEYDSVKSLRYGHLMIMTDQDHD 541

Query: 1765 GSHIKGLLINFIHSFWPSLLRIPSFLVEFITPIVKATHKNGEKRSFYTMPEYESWKESLG 1586
            GSHIKGLLINFIHSFWPSLL+IPSFLVEFITPIVKATHKNG+  SFY+MPEYESWK  LG
Sbjct: 542  GSHIKGLLINFIHSFWPSLLKIPSFLVEFITPIVKATHKNGKVLSFYSMPEYESWKX-LG 600

Query: 1585 DKARSWSIKYYKGLGTSTDKEGKEYFKDLGKHKKDFVWADDHDGEAIELAFSKKKIEARK 1406
              A  WSIKYYKGLGTST KEGKEYFKDL KHKKDF+W DD DG+AIELAFSKKKIEARK
Sbjct: 601  GNASGWSIKYYKGLGTSTSKEGKEYFKDLHKHKKDFLWVDDRDGDAIELAFSKKKIEARK 660

Query: 1405 NWLRQFEPGTYLDQEDKLIKYRDFVNKELILFSIADLQRSIPSMVDGLKPGQRKILFCAF 1226
            NWLRQFEPGT LDQ++KLIKY DFVNKELILFS+ADLQRSIPSMVDGLKPGQRKILFCAF
Sbjct: 661  NWLRQFEPGTCLDQKEKLIKYSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKILFCAF 720

Query: 1225 KRNFVHEAKVGQFAGYVSEHSAYHHGEQSLASTIIGMAQQYVGSNNINILKPNGQFGTRN 1046
            KRN + EAKV QF+GYVSEHSAYHHGEQSL STIIGMAQ YVGSNNIN+ +PNGQFGTR+
Sbjct: 721  KRNLIKEAKVAQFSGYVSEHSAYHHGEQSLMSTIIGMAQDYVGSNNINLFQPNGQFGTRH 780

Query: 1045 QGGKDHASARYIFTQLSAITRFLFPKDDDILLDYQNEDGQTIEPTWYVPIIPVVLVNGSE 866
            QGGKDHASARYI+T+LS ITRFLFPK DDILLDY NEDGQ+IEPTWY+PIIP VLVNGSE
Sbjct: 781  QGGKDHASARYIYTRLSPITRFLFPKGDDILLDYLNEDGQSIEPTWYMPIIPTVLVNGSE 840

Query: 865  GIGTGWSSFVPNYNPRDIIANVRHMLRDEPMEPMDPWYKGFRGTIEKTATKEAGATYTVT 686
            GIGTGWSS++PNYNPRDI+AN++ +L  EPMEPMDPWYKGF+G IEKTATKEAG++YTV+
Sbjct: 841  GIGTGWSSYIPNYNPRDIVANIKRLLNGEPMEPMDPWYKGFKGLIEKTATKEAGSSYTVS 900

Query: 685  GIIEEVSDTTLRVTELPVRKWTQDYKDFLESLY--------PFIEDVREYHTTDSVNFEI 530
            GIIEE+++TTLR+TELP+R+WTQDYK+FLES+         PFI+D +E++   +V+FEI
Sbjct: 901  GIIEEINETTLRITELPIRRWTQDYKEFLESIMTGNDKIKEPFIKDYKEHNDDTTVHFEI 960

Query: 529  DLSEENMRIAKQEGLLKKFKLTTTISTSNMHLFDSKGVIKKYDTPEKILEDFFSIRFEFY 350
             LSEEN+ +AKQEGL+KKFKLTTTISTSNMHLFD KG IKKYD PE+ILE+FF +R EFY
Sbjct: 961  ILSEENLMMAKQEGLMKKFKLTTTISTSNMHLFDPKGTIKKYDNPEQILEEFFHLRLEFY 1020

Query: 349  EKRKKALMDNLERELLILENKVRFIMDVVEGKIVVSNRRRADLVLELKEKGFTPFPKKAK 170
            EKRKK  +DNLE +LL L+NKVRFI+ VV+G+I+VSNR+R DL LEL++KGFTPFPKK K
Sbjct: 1021 EKRKKTQLDNLELDLLKLDNKVRFILGVVKGEIIVSNRKRVDLFLELQQKGFTPFPKKTK 1080

Query: 169  TTEISVAGSTDVPEETEENSDMATSQGVRASDYEYLLSMSIGSLTIEKVQELCNNR 2
              E +VAG+ +  EE EENS++ +S+GVRASDYEYLLSM+IG+LT+EKVQELC++R
Sbjct: 1081 ALEAAVAGANEDGEENEENSEVVSSRGVRASDYEYLLSMAIGTLTLEKVQELCSDR 1136


>ref|XP_002274267.1| PREDICTED: DNA topoisomerase 2 [Vitis vinifera]
          Length = 1489

 Score = 1803 bits (4669), Expect = 0.0
 Identities = 884/1136 (77%), Positives = 1000/1136 (88%), Gaps = 18/1136 (1%)
 Frame = -1

Query: 3355 KAPLTSSNNANIPPEXXXXXXXXXAKTIEQTYQKKTQLEHILLRPDTYIGSIEKHNQTLW 3176
            K PL SSNNAN+P +          KTIE+TYQKK+QLEHILLRPDTYIGSIEKH Q LW
Sbjct: 6    KLPLQSSNNANMPAKPAG-------KTIEETYQKKSQLEHILLRPDTYIGSIEKHTQALW 58

Query: 3175 VYEEKQMVQKPITYVPGLYKIFDEILVNAADNKQRDPKMNSLKVTIDAEANCISVYNNGD 2996
            V+E  +MV + ++YVPGLYKIFDEILVNAADNKQRDP M+S+KV ID E NCISVYNNGD
Sbjct: 59   VFENNEMVHRSVSYVPGLYKIFDEILVNAADNKQRDPSMDSVKVVIDVEKNCISVYNNGD 118

Query: 2995 GVPVEIHQEEGVYVPELIFGHLLTSSNYDDHEKKTTGGRNGYGAKLTNIFSTEFVIETAD 2816
            GVPVEIHQEEGVYVPE+IFGHLLTSSNYDD  KKTTGGRNGYGAKLTNIFSTEFVIETAD
Sbjct: 119  GVPVEIHQEEGVYVPEMIFGHLLTSSNYDDDVKKTTGGRNGYGAKLTNIFSTEFVIETAD 178

Query: 2815 GRRQRKYKQVFTCNMGNKSQPVISKCKESENWTKVTFKPDLSKFNMTHLEDDVVALMKKR 2636
            GRRQ+KYKQVF+ NMG KS+PVI+KCKE ENWTKV+FKPDL+KFNMTHLEDDVVALMKKR
Sbjct: 179  GRRQKKYKQVFSNNMGKKSEPVITKCKERENWTKVSFKPDLAKFNMTHLEDDVVALMKKR 238

Query: 2635 VIDMAGCLGKNVKVELNGEDIRVRSFGDYCNLYLKSAF--------RIEEKV-DRWEVCV 2483
            V+D+AGCLGK VKVELNG+ I V+SF DY NLYL+SA         RI EKV +RWE+CV
Sbjct: 239  VVDIAGCLGKTVKVELNGQRIPVKSFNDYVNLYLQSAAKSRPESLPRIAEKVNERWEICV 298

Query: 2482 SLSDGQFQQVSFVNSISTIKGGTHVDYVTNQIATHLAEYVNKKRKNANLKPHSVRNHLWV 2303
            SLS+GQFQQVSFVNSI+TIKGGTHVDYVTNQIA  +   VNKK KNAN+K H+V+NHLWV
Sbjct: 299  SLSEGQFQQVSFVNSIATIKGGTHVDYVTNQIANFVMSIVNKKNKNANIKAHTVKNHLWV 358

Query: 2302 FVNCLIDNPAFDSQTKETLTLRQKSFGSECKLSDKFLSKVANSEIVNNILEWAEFKEKKD 2123
            FVN LIDNPAFDSQTKETLT+RQ SFGS+C+LS +FL KV+ S +V ++L WA++K+ KD
Sbjct: 359  FVNALIDNPAFDSQTKETLTIRQSSFGSKCELSQEFLKKVSKSGVVESLLSWADYKQNKD 418

Query: 2122 LKKTDGTKSKRITGLTKLADANNAGGRNSEKCTLILTEGDSAATLAIAGLSVVGRDHYGV 1943
            LKKTDGTK +R+TG+TKL DAN+AGGRNSEKCTLILTEGDSA  LA+AG+SVVGR+HYGV
Sbjct: 419  LKKTDGTKRQRLTGITKLEDANDAGGRNSEKCTLILTEGDSAKALAMAGISVVGRNHYGV 478

Query: 1942 FPLRGKLLNVRDASTKQINDNAEIQNIKKILGLQHGKQYDSIKSLRYGHLMIMTDQDHDG 1763
            FPLRGKLLNVRDA  KQI +NAEIQNIK+ILGLQ GK+YDSIKSLRYGHLMIMTDQDHDG
Sbjct: 479  FPLRGKLLNVRDAQKKQILENAEIQNIKQILGLQQGKEYDSIKSLRYGHLMIMTDQDHDG 538

Query: 1762 SHIKGLLINFIHSFWPSLLRIPSFLVEFITPIVKATHKNGEKRSFYTMPEYESWKESLGD 1583
            SHIKGLLINFIHSFWPSLL+IPSFLVEFITPIVKATH+NG   SFY+MPEYESWKESLG 
Sbjct: 539  SHIKGLLINFIHSFWPSLLKIPSFLVEFITPIVKATHRNGRVLSFYSMPEYESWKESLGG 598

Query: 1582 KARSWSIKYYKGLGTSTDKEGKEYFKDLGKHKKDFVWADDHDGEAIELAFSKKKIEARKN 1403
             A  WSIKYYKGLGTST KEGKEYFKDLGKHKKDF+W D+ DG+AIELAFSKKKIE RKN
Sbjct: 599  NASGWSIKYYKGLGTSTSKEGKEYFKDLGKHKKDFMWVDEKDGDAIELAFSKKKIEERKN 658

Query: 1402 WLRQFEPGTYLDQEDKLIKYRDFVNKELILFSIADLQRSIPSMVDGLKPGQRKILFCAFK 1223
            WLRQF+PGTYLDQ++KLIKY DFVNKELILFS+ADLQRSIPSMVDGLKPGQRKILFC+FK
Sbjct: 659  WLRQFQPGTYLDQKEKLIKYSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKILFCSFK 718

Query: 1222 RNFVHEAKVGQFAGYVSEHSAYHHGEQSLASTIIGMAQQYVGSNNINILKPNGQFGTRNQ 1043
            RNF+ EAK+ QF+GYVSEHSAYHHGEQSLASTIIGMAQ +VGSNNIN+L PNGQFGTR+Q
Sbjct: 719  RNFIKEAKIAQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRHQ 778

Query: 1042 GGKDHASARYIFTQLSAITRFLFPKDDDILLDYQNEDGQTIEPTWYVPIIPVVLVNGSEG 863
            GGKDHASARYI+T+LS ITRFLFPKDDDILLDY NEDGQ+IEPTWYVP IP+VLVNGSEG
Sbjct: 779  GGKDHASARYIYTRLSPITRFLFPKDDDILLDYLNEDGQSIEPTWYVPTIPMVLVNGSEG 838

Query: 862  IGTGWSSFVPNYNPRDIIANVRHMLRDEPMEPMDPWYKGFRGTIEKT-ATKEAGATYTVT 686
            IGTGWSS +PNYNPRDIIANVR +L  E MEPMDPWY+GFRGTIEKT  TK+    YTV 
Sbjct: 839  IGTGWSSSIPNYNPRDIIANVRRLLNGEMMEPMDPWYRGFRGTIEKTDPTKQESVGYTVK 898

Query: 685  GIIEEVSDTTLRVTELPVRKWTQDYKDFLESLY--------PFIEDVREYHTTDSVNFEI 530
            GIIEEV++TTLR++ELPVRKWTQDYK+FLES+         PFI+D +E++   +V+FE+
Sbjct: 899  GIIEEVNETTLRISELPVRKWTQDYKEFLESIMTGNDKIKDPFIKDYKEHNDDTTVHFEV 958

Query: 529  DLSEENMRIAKQEGLLKKFKLTTTISTSNMHLFDSKGVIKKYDTPEKILEDFFSIRFEFY 350
             +SEEN+ +AKQEGLL+KFKLTT ISTSNMHLFDS G IKKY+TPE+ILE+FF +R EFY
Sbjct: 959  IMSEENLLMAKQEGLLQKFKLTTKISTSNMHLFDSNGTIKKYETPEQILEEFFHLRLEFY 1018

Query: 349  EKRKKALMDNLERELLILENKVRFIMDVVEGKIVVSNRRRADLVLELKEKGFTPFPKKAK 170
            EKRK+ L+DNLE ELL LENKVRFI+ VV G+I+VSNR+RADL  EL +KGFTPFPKK+K
Sbjct: 1019 EKRKRVLLDNLELELLKLENKVRFILGVVRGEIIVSNRKRADLFHELHQKGFTPFPKKSK 1078

Query: 169  TTEISVAGSTDVPEETEENSDMATSQGVRASDYEYLLSMSIGSLTIEKVQELCNNR 2
            + EI+VAG+TD  EE EEN+D  +  GVRA+DYEYLLSM+IG+LT+EKVQELC +R
Sbjct: 1079 SVEIAVAGATDDTEEAEENTDAVSKGGVRATDYEYLLSMAIGTLTLEKVQELCADR 1134


>ref|XP_012849677.1| PREDICTED: DNA topoisomerase 2 [Erythranthe guttatus]
            gi|604314150|gb|EYU27037.1| hypothetical protein
            MIMGU_mgv1a000169mg [Erythranthe guttata]
          Length = 1503

 Score = 1784 bits (4620), Expect = 0.0
 Identities = 883/1143 (77%), Positives = 993/1143 (86%), Gaps = 24/1143 (2%)
 Frame = -1

Query: 3358 KKAPLTSSNNANIPPEXXXXXXXXXA---KTIEQTYQKKTQLEHILLRPDTYIGSIEKHN 3188
            KK PLT+SNNANIPP              KTIEQTYQKKTQLEHILLRPDTYIGSIEKH 
Sbjct: 5    KKPPLTTSNNANIPPSETTAAAAAAGGGKKTIEQTYQKKTQLEHILLRPDTYIGSIEKHT 64

Query: 3187 QTLWVYEEKQMVQKPITYVPGLYKIFDEILVNAADNKQRDPKMNSLKVTIDAEANCISVY 3008
            QTLW+YE + MVQK ITYVPGLYKIFDEILVNAADNKQRDP+M+S+KVTID E+N ISVY
Sbjct: 65   QTLWIYENENMVQKSITYVPGLYKIFDEILVNAADNKQRDPRMDSVKVTIDVESNYISVY 124

Query: 3007 NNGDGVPVEIHQEEGVYVPELIFGHLLTSSNYDDHEKKTTGGRNGYGAKLTNIFSTEFVI 2828
            NNGDGVPVEIHQEEGVYVPELIFGHLLTSSNYDD+EKKTTGGRNGYGAKLTNIFSTEFVI
Sbjct: 125  NNGDGVPVEIHQEEGVYVPELIFGHLLTSSNYDDNEKKTTGGRNGYGAKLTNIFSTEFVI 184

Query: 2827 ETADGRRQRKYKQVFTCNMGNKSQPVISKCKESENWTKVTFKPDLSKFNMTHLEDDVVAL 2648
            ETADG+R +KYKQVF+ NMG KS+PVISKCK  ENWTK+TFKPDL+KF+M+ LE+DVVAL
Sbjct: 185  ETADGKRLKKYKQVFSNNMGTKSEPVISKCKSGENWTKITFKPDLTKFSMSCLEEDVVAL 244

Query: 2647 MKKRVIDMAGCLGKNVKVELNGEDIRVRSFGDYCNLYLKSAF--------RIEEKV-DRW 2495
            MKKRVID+AGCLGK VKVELNG+    +SF +YC+LYLKSA         R EE+V DRW
Sbjct: 245  MKKRVIDIAGCLGKTVKVELNGQQFHFKSFSNYCDLYLKSASLASSEPLPRFEEEVHDRW 304

Query: 2494 EVCVSLSDGQFQQVSFVNSISTIKGGTHVDYVTNQIATHLAEYV---NKKRKNANLKPHS 2324
            +VCVS S+GQFQQVSFVN I+TIKGGTHVDYVTN+I +HL   +   NKK K  +LKPH+
Sbjct: 305  QVCVSRSEGQFQQVSFVNGIATIKGGTHVDYVTNKITSHLVAVIKNKNKKNKKFDLKPHT 364

Query: 2323 VRNHLWVFVNCLIDNPAFDSQTKETLTLRQKSFGSECKLSDKFLSKVANSEIVNNILEWA 2144
            V+NHLWVFVN LIDNPAFDSQTKETLTLR  SFGS    S KFL KV+ S+I+ NI EWA
Sbjct: 365  VKNHLWVFVNALIDNPAFDSQTKETLTLRAGSFGSSWDFSSKFLDKVSKSDIMKNIEEWA 424

Query: 2143 EFKEKKDLKKTDGTKSKRITGLTKLADANNAGGRNSEKCTLILTEGDSAATLAIAGLSVV 1964
            EFK+KKDLKKTDG K +RI GLTKLADAN AGG+NSEKCTLILTEGDSA  LAIAG+SVV
Sbjct: 425  EFKQKKDLKKTDGAKDRRIYGLTKLADANEAGGKNSEKCTLILTEGDSAKALAIAGISVV 484

Query: 1963 GRDHYGVFPLRGKLLNVRDASTKQINDNAEIQNIKKILGLQHGKQYDSIKSLRYGHLMIM 1784
            GRDHYGVFPLRGKLLNVR+AS  Q+  N EIQ+IK+ILGLQHGKQYDS+KSLRYGHLMIM
Sbjct: 485  GRDHYGVFPLRGKLLNVREASHTQLMQNVEIQHIKQILGLQHGKQYDSVKSLRYGHLMIM 544

Query: 1783 TDQDHDGSHIKGLLINFIHSFWPSLLRIPSFLVEFITPIVKATHKNGE-KRSFYTMPEYE 1607
            TDQDHDGSHIKGLLINFIHSFWPSLL++PSF++EFITPIVKAT+K G+ K+SFYTMP+YE
Sbjct: 545  TDQDHDGSHIKGLLINFIHSFWPSLLKVPSFMLEFITPIVKATNKYGKNKKSFYTMPQYE 604

Query: 1606 SWKESLGDKARSWSIKYYKGLGTSTDKEGKEYFKDLGKHKKDFVWADDHDGEAIELAFSK 1427
            +WKES+G  A++W+IKYYKGLGTSTDKEGKEYF+DLGKHKKDFVW D+ DG+AIELAFSK
Sbjct: 605  AWKESIGSDAKNWTIKYYKGLGTSTDKEGKEYFEDLGKHKKDFVWVDEQDGDAIELAFSK 664

Query: 1426 KKIEARKNWLRQFEPGTYLDQEDKLIKYRDFVNKELILFSIADLQRSIPSMVDGLKPGQR 1247
            KKIEARK+WLRQFEPGTYLD  D  IKYRDFV+KELILFSIADLQRSIPSMVDGLKPGQR
Sbjct: 665  KKIEARKSWLRQFEPGTYLDDRDSHIKYRDFVHKELILFSIADLQRSIPSMVDGLKPGQR 724

Query: 1246 KILFCAFKRNFVHEAKVGQFAGYVSEHSAYHHGEQSLASTIIGMAQQYVGSNNINILKPN 1067
            KIL+C+FKRNFV EAKV QF+GYVSEHSAYHHGEQSLASTIIGMAQ YVGSNNIN+L PN
Sbjct: 725  KILYCSFKRNFVKEAKVAQFSGYVSEHSAYHHGEQSLASTIIGMAQDYVGSNNINLLLPN 784

Query: 1066 GQFGTRNQGGKDHASARYIFTQLSAITRFLFPKDDDILLDYQNEDGQTIEPTWYVPIIPV 887
            GQFGTR QGGKDHASARY++TQLS +TRFLFPK DDILLDY NEDGQ IEPTWYVPIIP 
Sbjct: 785  GQFGTRGQGGKDHASARYVYTQLSPVTRFLFPKADDILLDYLNEDGQMIEPTWYVPIIPT 844

Query: 886  VLVNGSEGIGTGWSSFVPNYNPRDIIANVRHMLRDEPMEPMDPWYKGFRGTIEKTATKEA 707
            VLVNGSEGIGTGWSSFVPNYNP DIIANVRH+L  EPME M PWYKGF+GTIEKTATKEA
Sbjct: 845  VLVNGSEGIGTGWSSFVPNYNPLDIIANVRHLLNGEPMEAMHPWYKGFKGTIEKTATKEA 904

Query: 706  GATYTVTGIIEEVSDTTLRVTELPVRKWTQDYKDFLESLY--------PFIEDVREYHTT 551
            G +YTVTGIIEEV +TTL +TELP+R+WTQDYK+FLES+         PFIE  R+    
Sbjct: 905  GFSYTVTGIIEEVDETTLTITELPIRRWTQDYKEFLESISAENDKSKDPFIEGCRDNSGG 964

Query: 550  DSVNFEIDLSEENMRIAKQEGLLKKFKLTTTISTSNMHLFDSKGVIKKYDTPEKILEDFF 371
            + ++F + LSE N+ +AKQEGLLKKFKLTTT+STSNMHLFDSKGVIKKYD+PE+ILE+FF
Sbjct: 965  EIIHFAVYLSETNLLVAKQEGLLKKFKLTTTMSTSNMHLFDSKGVIKKYDSPEQILEEFF 1024

Query: 370  SIRFEFYEKRKKALMDNLERELLILENKVRFIMDVVEGKIVVSNRRRADLVLELKEKGFT 191
             IR EFYEKRKKAL+ NLE ++L  +NK RFI  VVEG IVVSNR++ADL LELK KGFT
Sbjct: 1025 YIRLEFYEKRKKALLANLELDMLKCDNKYRFIRGVVEGTIVVSNRKKADLFLELKAKGFT 1084

Query: 190  PFPKKAKTTEISVAGSTDVPEETEENSDMATSQGVRASDYEYLLSMSIGSLTIEKVQELC 11
            PFPKK  T E++VAG+TD  EETE+N+++  ++GV ASDY+YLLS++IG+LT EK+QEL 
Sbjct: 1085 PFPKKKNTPEVAVAGATDDTEETEDNTEVEIAKGVSASDYDYLLSLAIGTLTAEKLQELR 1144

Query: 10   NNR 2
            + R
Sbjct: 1145 DER 1147


>ref|XP_011087923.1| PREDICTED: DNA topoisomerase 2 isoform X2 [Sesamum indicum]
          Length = 1483

 Score = 1782 bits (4616), Expect = 0.0
 Identities = 884/1137 (77%), Positives = 990/1137 (87%), Gaps = 22/1137 (1%)
 Frame = -1

Query: 3358 KKAPLTSSNNANIPP-EXXXXXXXXXAKTIEQTYQKKTQLEHILLRPDTYIGSIEKHNQT 3182
            KKAPLT+SNNANIPP E          KTIEQTYQKKTQLEHILLRPDTYIGSIEKH QT
Sbjct: 5    KKAPLTTSNNANIPPPETTIAGGGAGKKTIEQTYQKKTQLEHILLRPDTYIGSIEKHTQT 64

Query: 3181 LWVYEEKQMVQKPITYVPGLYKIFDEILVNAADNKQRDPKMNSLKVTIDAEANCISVYNN 3002
            LWVYE++QMVQK ITYVPGLYKIFDEILVNAADNKQRDPKM+S+KVTID E+N ISVYNN
Sbjct: 65   LWVYEDEQMVQKSITYVPGLYKIFDEILVNAADNKQRDPKMDSVKVTIDVESNSISVYNN 124

Query: 3001 GDGVPVEIHQEEGVYVPELIFGHLLTSSNYDDHEKKTTGGRNGYGAKLTNIFSTEFVIET 2822
            GDGVPVEIHQEEGVYVPELIFGHLLTSSNYDD+EKKTTGGRNGYGAKLTNIFSTEFVIET
Sbjct: 125  GDGVPVEIHQEEGVYVPELIFGHLLTSSNYDDNEKKTTGGRNGYGAKLTNIFSTEFVIET 184

Query: 2821 ADGRRQRKYKQVFTCNMGNKSQPVISKCKESENWTKVTFKPDLSKFNMTHLEDDVVALMK 2642
            ADG+RQRKYKQVF+ NMG KS+P+ISKCK  ENWTK+TFKPDL+KF+M++LE+DVVALMK
Sbjct: 185  ADGKRQRKYKQVFSNNMGTKSEPIISKCKAGENWTKITFKPDLAKFSMSYLEEDVVALMK 244

Query: 2641 KRVIDMAGCLGKNVKVELNGEDIRVRSFGDYCNLYLKSAF--------RIEEKV-DRWEV 2489
            KRVID+AGCLGK VKVELNG     +SF +YC+LYLK A         R EE+V DRW++
Sbjct: 245  KRVIDVAGCLGKTVKVELNGRLFHFKSFSNYCDLYLKPASASSSDPLPRFEEEVHDRWQI 304

Query: 2488 CVSLSDGQFQQVSFVNSISTIKGGTHVDYVTNQIATHLAEYV---NKKRKNANLKPHSVR 2318
            C+S S+GQFQQVSFVN I+T+KGGTHVDYVTN+I +HL   +   NKK K  +LKPH+V+
Sbjct: 305  CISRSEGQFQQVSFVNGIATVKGGTHVDYVTNKITSHLVTVIKNKNKKNKKFDLKPHAVK 364

Query: 2317 NHLWVFVNCLIDNPAFDSQTKETLTLRQKSFGSECKLSDKFLSKVANSEIVNNILEWAEF 2138
            NHLWVFVN LIDNPAFDSQTKETLTLR  SFGS    S KFL KVA S+I+ NI EWAEF
Sbjct: 365  NHLWVFVNALIDNPAFDSQTKETLTLRAASFGSSWDFSSKFLDKVAKSDIMKNIEEWAEF 424

Query: 2137 KEKKDLKKTDGTKSKRITGLTKLADANNAGGRNSEKCTLILTEGDSAATLAIAGLSVVGR 1958
            K+KKDLKKTDG+K +RI GLTKLADAN AGG+NSEKCTLILTEGDSA  LAIAGLSVVGR
Sbjct: 425  KQKKDLKKTDGSKDRRIYGLTKLADANEAGGKNSEKCTLILTEGDSAKALAIAGLSVVGR 484

Query: 1957 DHYGVFPLRGKLLNVRDASTKQINDNAEIQNIKKILGLQHGKQYDSIKSLRYGHLMIMTD 1778
            DHYGVFPLRGKLLNVR+AS  Q+  N EIQ+IK+ILGLQHGKQYDS+KSLRYGHLMIMTD
Sbjct: 485  DHYGVFPLRGKLLNVREASHNQLMQNVEIQHIKQILGLQHGKQYDSVKSLRYGHLMIMTD 544

Query: 1777 QDHDGSHIKGLLINFIHSFWPSLLRIPSFLVEFITPIVKATHKNGEKR-SFYTMPEYESW 1601
            QDHDGSHIKGLLINFIHSFWPSLL++P+FL+EFITPIVKA+ K+G+K+ SFYTMP+YE+W
Sbjct: 545  QDHDGSHIKGLLINFIHSFWPSLLKVPTFLLEFITPIVKASRKDGKKKESFYTMPQYEAW 604

Query: 1600 KESLGDKARSWSIKYYKGLGTSTDKEGKEYFKDLGKHKKDFVWADDHDGEAIELAFSKKK 1421
            KE LG  A++WSIKYYKGLGTSTD+EGKEYF+DLGKHKKDFVW D+ DGEAIELAFSKKK
Sbjct: 605  KEKLGADAKNWSIKYYKGLGTSTDQEGKEYFEDLGKHKKDFVWVDEQDGEAIELAFSKKK 664

Query: 1420 IEARKNWLRQFEPGTYLDQEDKLIKYRDFVNKELILFSIADLQRSIPSMVDGLKPGQRKI 1241
            IEARKNW+RQFEPGTYL ++DK IKYRDFV+KELILFSIADLQRSIPSMVDGLKPGQRKI
Sbjct: 665  IEARKNWIRQFEPGTYLSEQDKHIKYRDFVHKELILFSIADLQRSIPSMVDGLKPGQRKI 724

Query: 1240 LFCAFKRNFVHEAKVGQFAGYVSEHSAYHHGEQSLASTIIGMAQQYVGSNNINILKPNGQ 1061
            LFC+FKRNF+ EAKV QF+GYVSEHSAYHHGEQSLASTIIGMAQ YVGSNNIN+L PNGQ
Sbjct: 725  LFCSFKRNFIKEAKVAQFSGYVSEHSAYHHGEQSLASTIIGMAQDYVGSNNINLLLPNGQ 784

Query: 1060 FGTRNQGGKDHASARYIFTQLSAITRFLFPKDDDILLDYQNEDGQTIEPTWYVPIIPVVL 881
            FGTR QGGKDHASARYIFTQLS ITR+LFPK DDILL+Y NEDGQ+IEP+WYVPIIP+VL
Sbjct: 785  FGTRGQGGKDHASARYIFTQLSPITRYLFPKADDILLNYLNEDGQSIEPSWYVPIIPMVL 844

Query: 880  VNGSEGIGTGWSSFVPNYNPRDIIANVRHMLRDEPMEPMDPWYKGFRGTIEKTATKEAGA 701
            VNGSEGIGTGWSSF+PNYNP DIIAN+RH+L DEPM PM PWYKGFRG+IEKTATKEAG 
Sbjct: 845  VNGSEGIGTGWSSFIPNYNPLDIIANLRHLLNDEPMVPMHPWYKGFRGSIEKTATKEAGN 904

Query: 700  TYTVTGIIEEVSDTTLRVTELPVRKWTQDYKDFLESLY--------PFIEDVREYHTTDS 545
            +YTV+GIIEE+ + TL +TELPVRKWTQDYK+FLES+         PFIE  R+    + 
Sbjct: 905  SYTVSGIIEELDERTLSITELPVRKWTQDYKEFLESISAENEKSKDPFIEGCRDNSGGEI 964

Query: 544  VNFEIDLSEENMRIAKQEGLLKKFKLTTTISTSNMHLFDSKGVIKKYDTPEKILEDFFSI 365
            VNF + LS EN+ IAKQEGLLKKFKLTT+ISTSNMHLFD+KGVIKKYDTPE+ILE+FF I
Sbjct: 965  VNFLVYLSAENLLIAKQEGLLKKFKLTTSISTSNMHLFDAKGVIKKYDTPEQILEEFFHI 1024

Query: 364  RFEFYEKRKKALMDNLERELLILENKVRFIMDVVEGKIVVSNRRRADLVLELKEKGFTPF 185
            R EFYEKRK+ L+ NLE ++L  ENK RFI  VVE  I+VSNRRRADL LELKEKGFTPF
Sbjct: 1025 RLEFYEKRKRVLLANLENDMLKCENKCRFIQCVVESSIIVSNRRRADLFLELKEKGFTPF 1084

Query: 184  PKKAKTTEISVAGSTDVPEETEENSDMATSQGVRASDYEYLLSMSIGSLTIEKVQEL 14
            PKK    E+++AGS D  EETEEN+         ASDY+YLLS++IG+LT EK+QEL
Sbjct: 1085 PKKKTAAEVAIAGSLDEAEETEENTS--------ASDYDYLLSLAIGTLTAEKIQEL 1133


>ref|XP_011087914.1| PREDICTED: DNA topoisomerase 2 isoform X1 [Sesamum indicum]
          Length = 1484

 Score = 1782 bits (4616), Expect = 0.0
 Identities = 884/1137 (77%), Positives = 990/1137 (87%), Gaps = 22/1137 (1%)
 Frame = -1

Query: 3358 KKAPLTSSNNANIPP-EXXXXXXXXXAKTIEQTYQKKTQLEHILLRPDTYIGSIEKHNQT 3182
            KKAPLT+SNNANIPP E          KTIEQTYQKKTQLEHILLRPDTYIGSIEKH QT
Sbjct: 5    KKAPLTTSNNANIPPPETTIAGGGAGKKTIEQTYQKKTQLEHILLRPDTYIGSIEKHTQT 64

Query: 3181 LWVYEEKQMVQKPITYVPGLYKIFDEILVNAADNKQRDPKMNSLKVTIDAEANCISVYNN 3002
            LWVYE++QMVQK ITYVPGLYKIFDEILVNAADNKQRDPKM+S+KVTID E+N ISVYNN
Sbjct: 65   LWVYEDEQMVQKSITYVPGLYKIFDEILVNAADNKQRDPKMDSVKVTIDVESNSISVYNN 124

Query: 3001 GDGVPVEIHQEEGVYVPELIFGHLLTSSNYDDHEKKTTGGRNGYGAKLTNIFSTEFVIET 2822
            GDGVPVEIHQEEGVYVPELIFGHLLTSSNYDD+EKKTTGGRNGYGAKLTNIFSTEFVIET
Sbjct: 125  GDGVPVEIHQEEGVYVPELIFGHLLTSSNYDDNEKKTTGGRNGYGAKLTNIFSTEFVIET 184

Query: 2821 ADGRRQRKYKQVFTCNMGNKSQPVISKCKESENWTKVTFKPDLSKFNMTHLEDDVVALMK 2642
            ADG+RQRKYKQVF+ NMG KS+P+ISKCK  ENWTK+TFKPDL+KF+M++LE+DVVALMK
Sbjct: 185  ADGKRQRKYKQVFSNNMGTKSEPIISKCKAGENWTKITFKPDLAKFSMSYLEEDVVALMK 244

Query: 2641 KRVIDMAGCLGKNVKVELNGEDIRVRSFGDYCNLYLKSAF--------RIEEKV-DRWEV 2489
            KRVID+AGCLGK VKVELNG     +SF +YC+LYLK A         R EE+V DRW++
Sbjct: 245  KRVIDVAGCLGKTVKVELNGRLFHFKSFSNYCDLYLKPASASSSDPLPRFEEEVHDRWQI 304

Query: 2488 CVSLSDGQFQQVSFVNSISTIKGGTHVDYVTNQIATHLAEYV---NKKRKNANLKPHSVR 2318
            C+S S+GQFQQVSFVN I+T+KGGTHVDYVTN+I +HL   +   NKK K  +LKPH+V+
Sbjct: 305  CISRSEGQFQQVSFVNGIATVKGGTHVDYVTNKITSHLVTVIKNKNKKNKKFDLKPHAVK 364

Query: 2317 NHLWVFVNCLIDNPAFDSQTKETLTLRQKSFGSECKLSDKFLSKVANSEIVNNILEWAEF 2138
            NHLWVFVN LIDNPAFDSQTKETLTLR  SFGS    S KFL KVA S+I+ NI EWAEF
Sbjct: 365  NHLWVFVNALIDNPAFDSQTKETLTLRAASFGSSWDFSSKFLDKVAKSDIMKNIEEWAEF 424

Query: 2137 KEKKDLKKTDGTKSKRITGLTKLADANNAGGRNSEKCTLILTEGDSAATLAIAGLSVVGR 1958
            K+KKDLKKTDG+K +RI GLTKLADAN AGG+NSEKCTLILTEGDSA  LAIAGLSVVGR
Sbjct: 425  KQKKDLKKTDGSKDRRIYGLTKLADANEAGGKNSEKCTLILTEGDSAKALAIAGLSVVGR 484

Query: 1957 DHYGVFPLRGKLLNVRDASTKQINDNAEIQNIKKILGLQHGKQYDSIKSLRYGHLMIMTD 1778
            DHYGVFPLRGKLLNVR+AS  Q+  N EIQ+IK+ILGLQHGKQYDS+KSLRYGHLMIMTD
Sbjct: 485  DHYGVFPLRGKLLNVREASHNQLMQNVEIQHIKQILGLQHGKQYDSVKSLRYGHLMIMTD 544

Query: 1777 QDHDGSHIKGLLINFIHSFWPSLLRIPSFLVEFITPIVKATHKNGEKR-SFYTMPEYESW 1601
            QDHDGSHIKGLLINFIHSFWPSLL++P+FL+EFITPIVKA+ K+G+K+ SFYTMP+YE+W
Sbjct: 545  QDHDGSHIKGLLINFIHSFWPSLLKVPTFLLEFITPIVKASRKDGKKKESFYTMPQYEAW 604

Query: 1600 KESLGDKARSWSIKYYKGLGTSTDKEGKEYFKDLGKHKKDFVWADDHDGEAIELAFSKKK 1421
            KE LG  A++WSIKYYKGLGTSTD+EGKEYF+DLGKHKKDFVW D+ DGEAIELAFSKKK
Sbjct: 605  KEKLGADAKNWSIKYYKGLGTSTDQEGKEYFEDLGKHKKDFVWVDEQDGEAIELAFSKKK 664

Query: 1420 IEARKNWLRQFEPGTYLDQEDKLIKYRDFVNKELILFSIADLQRSIPSMVDGLKPGQRKI 1241
            IEARKNW+RQFEPGTYL ++DK IKYRDFV+KELILFSIADLQRSIPSMVDGLKPGQRKI
Sbjct: 665  IEARKNWIRQFEPGTYLSEQDKHIKYRDFVHKELILFSIADLQRSIPSMVDGLKPGQRKI 724

Query: 1240 LFCAFKRNFVHEAKVGQFAGYVSEHSAYHHGEQSLASTIIGMAQQYVGSNNINILKPNGQ 1061
            LFC+FKRNF+ EAKV QF+GYVSEHSAYHHGEQSLASTIIGMAQ YVGSNNIN+L PNGQ
Sbjct: 725  LFCSFKRNFIKEAKVAQFSGYVSEHSAYHHGEQSLASTIIGMAQDYVGSNNINLLLPNGQ 784

Query: 1060 FGTRNQGGKDHASARYIFTQLSAITRFLFPKDDDILLDYQNEDGQTIEPTWYVPIIPVVL 881
            FGTR QGGKDHASARYIFTQLS ITR+LFPK DDILL+Y NEDGQ+IEP+WYVPIIP+VL
Sbjct: 785  FGTRGQGGKDHASARYIFTQLSPITRYLFPKADDILLNYLNEDGQSIEPSWYVPIIPMVL 844

Query: 880  VNGSEGIGTGWSSFVPNYNPRDIIANVRHMLRDEPMEPMDPWYKGFRGTIEKTATKEAGA 701
            VNGSEGIGTGWSSF+PNYNP DIIAN+RH+L DEPM PM PWYKGFRG+IEKTATKEAG 
Sbjct: 845  VNGSEGIGTGWSSFIPNYNPLDIIANLRHLLNDEPMVPMHPWYKGFRGSIEKTATKEAGN 904

Query: 700  TYTVTGIIEEVSDTTLRVTELPVRKWTQDYKDFLESLY--------PFIEDVREYHTTDS 545
            +YTV+GIIEE+ + TL +TELPVRKWTQDYK+FLES+         PFIE  R+    + 
Sbjct: 905  SYTVSGIIEELDERTLSITELPVRKWTQDYKEFLESISAENEKSKDPFIEGCRDNSGGEI 964

Query: 544  VNFEIDLSEENMRIAKQEGLLKKFKLTTTISTSNMHLFDSKGVIKKYDTPEKILEDFFSI 365
            VNF + LS EN+ IAKQEGLLKKFKLTT+ISTSNMHLFD+KGVIKKYDTPE+ILE+FF I
Sbjct: 965  VNFLVYLSAENLLIAKQEGLLKKFKLTTSISTSNMHLFDAKGVIKKYDTPEQILEEFFHI 1024

Query: 364  RFEFYEKRKKALMDNLERELLILENKVRFIMDVVEGKIVVSNRRRADLVLELKEKGFTPF 185
            R EFYEKRK+ L+ NLE ++L  ENK RFI  VVE  I+VSNRRRADL LELKEKGFTPF
Sbjct: 1025 RLEFYEKRKRVLLANLENDMLKCENKCRFIQCVVESSIIVSNRRRADLFLELKEKGFTPF 1084

Query: 184  PKKAKTTEISVAGSTDVPEETEENSDMATSQGVRASDYEYLLSMSIGSLTIEKVQEL 14
            PKK    E+++AGS D  EETEEN+         ASDY+YLLS++IG+LT EK+QEL
Sbjct: 1085 PKKKTAAEVAIAGSLDEAEETEENTS--------ASDYDYLLSLAIGTLTAEKIQEL 1133


>ref|XP_007009329.1| Topoisomerase II isoform 3 [Theobroma cacao]
            gi|508726242|gb|EOY18139.1| Topoisomerase II isoform 3
            [Theobroma cacao]
          Length = 1244

 Score = 1778 bits (4606), Expect = 0.0
 Identities = 872/1135 (76%), Positives = 994/1135 (87%), Gaps = 13/1135 (1%)
 Frame = -1

Query: 3367 MAPKKAPLTSSNNANIPPEXXXXXXXXXAKTIEQTYQKKTQLEHILLRPDTYIGSIEKHN 3188
            +A  K PL SSNNAN+             KTIE+TYQKKTQLEHILLRPDTYIGSIE+H 
Sbjct: 2    VADSKLPLQSSNNANMKAS----------KTIEETYQKKTQLEHILLRPDTYIGSIEQHT 51

Query: 3187 QTLWVYEEKQMVQKPITYVPGLYKIFDEILVNAADNKQRDPKMNSLKVTIDAEANCISVY 3008
            Q LWVYE  +MV + I YVPGLYKIFDEILVNAADNKQRDP M+S+KV IDAE N ISVY
Sbjct: 52   QRLWVYENDEMVHRDIKYVPGLYKIFDEILVNAADNKQRDPSMDSVKVVIDAEQNLISVY 111

Query: 3007 NNGDGVPVEIHQEEGVYVPELIFGHLLTSSNYDDHEKKTTGGRNGYGAKLTNIFSTEFVI 2828
            NNGDGVPVE+HQEEGVYVPELIFGHLLTSSNYDD  KKTTGGRNGYGAKLTNIFSTEF+I
Sbjct: 112  NNGDGVPVEVHQEEGVYVPELIFGHLLTSSNYDDTVKKTTGGRNGYGAKLTNIFSTEFII 171

Query: 2827 ETADGRRQRKYKQVFTCNMGNKSQPVISKCKESENWTKVTFKPDLSKFNMTHLEDDVVAL 2648
            ETADG+RQ+KYKQVF+ NMG KS+PVISKCKE+ENWTKVTFKPDL+KFNMTHLE+DVVAL
Sbjct: 172  ETADGKRQKKYKQVFSNNMGKKSEPVISKCKEAENWTKVTFKPDLAKFNMTHLEEDVVAL 231

Query: 2647 MKKRVIDMAGCLGKNVKVELNGEDIRVRSFGDYCNLYLKSAF--------RIEEKV-DRW 2495
            MKKRV D+AGCLGK VKVELNG+ + V+SF DY +LYL +A         R+ EKV +RW
Sbjct: 232  MKKRVFDVAGCLGKTVKVELNGKRVPVKSFLDYVSLYLSAASKTKTEPLPRLLEKVNERW 291

Query: 2494 EVCVSLSDGQFQQVSFVNSISTIKGGTHVDYVTNQIATHLAEYVNKKRKNANLKPHSVRN 2315
            EV VSLSDGQFQQVSFVN I+TIKGGTHVDYVTNQI+ ++   VNKK KNAN+K H+V+N
Sbjct: 292  EVGVSLSDGQFQQVSFVNGIATIKGGTHVDYVTNQISNYVMNIVNKKNKNANVKAHNVKN 351

Query: 2314 HLWVFVNCLIDNPAFDSQTKETLTLRQKSFGSECKLSDKFLSKVANSEIVNNILEWAEFK 2135
            HLWVFVN LIDNPAFDSQTKETLTLRQ SFGS+C+LS+ FL KVA   +V+N+L WAEFK
Sbjct: 352  HLWVFVNALIDNPAFDSQTKETLTLRQSSFGSKCELSEDFLKKVAKCGVVDNLLSWAEFK 411

Query: 2134 EKKDLKKTDGTKSKRITGLTKLADANNAGGRNSEKCTLILTEGDSAATLAIAGLSVVGRD 1955
              KDLKKTDG K+  I G+ KL DAN AGGRNS+KCTLILTEGDSA  LA+AGL+VVGR+
Sbjct: 412  HSKDLKKTDGAKTGSIRGIPKLDDANEAGGRNSDKCTLILTEGDSAKALAVAGLAVVGRN 471

Query: 1954 HYGVFPLRGKLLNVRDASTKQINDNAEIQNIKKILGLQHGKQYDSIKSLRYGHLMIMTDQ 1775
            HYGVFPLRGKLLNVR+AS KQ+ DNAEIQN+K+ILGLQ GK+Y ++KSLRYGHLMIMTDQ
Sbjct: 472  HYGVFPLRGKLLNVREASHKQLMDNAEIQNLKRILGLQQGKEYSNVKSLRYGHLMIMTDQ 531

Query: 1774 DHDGSHIKGLLINFIHSFWPSLLRIPSFLVEFITPIVKATHKNGEKRSFYTMPEYESWKE 1595
            DHDGSHIKGLLINFIHSFWPSLL++PSF+VEFITPIVKATHK     SFY+MPEYE WKE
Sbjct: 532  DHDGSHIKGLLINFIHSFWPSLLKVPSFMVEFITPIVKATHKTKGVLSFYSMPEYEFWKE 591

Query: 1594 SLGDKARSWSIKYYKGLGTSTDKEGKEYFKDLGKHKKDFVWADDHDGEAIELAFSKKKIE 1415
            SLG  A+ WSIKYYKGLGTST KEGK+YFK+L KH+K+FVW D+ DGEAIELAFSKKKIE
Sbjct: 592  SLGGNAKGWSIKYYKGLGTSTSKEGKDYFKNLDKHRKEFVWQDEQDGEAIELAFSKKKIE 651

Query: 1414 ARKNWLRQFEPGTYLDQEDKLIKYRDFVNKELILFSIADLQRSIPSMVDGLKPGQRKILF 1235
            ARKNWLRQFEPGT+LDQ  KLIKY +F+NKELILFS+ADLQRSIPSM+DGLKPGQRKILF
Sbjct: 652  ARKNWLRQFEPGTHLDQSQKLIKYSEFINKELILFSMADLQRSIPSMIDGLKPGQRKILF 711

Query: 1234 CAFKRNFVHEAKVGQFAGYVSEHSAYHHGEQSLASTIIGMAQQYVGSNNINILKPNGQFG 1055
            C+FKRNFV EAKV QF+GYVSEHSAYHHGEQSLASTI+GMAQ +VGSNNIN+L P GQFG
Sbjct: 712  CSFKRNFVKEAKVAQFSGYVSEHSAYHHGEQSLASTIVGMAQDFVGSNNINLLNPGGQFG 771

Query: 1054 TRNQGGKDHASARYIFTQLSAITRFLFPKDDDILLDYQNEDGQTIEPTWYVPIIPVVLVN 875
            TRNQGGKD ASARYIFT LS ITR+LFPKDDD LLDY NEDGQ+IEP WYVPIIP+VLVN
Sbjct: 772  TRNQGGKDAASARYIFTNLSPITRYLFPKDDDGLLDYLNEDGQSIEPIWYVPIIPMVLVN 831

Query: 874  GSEGIGTGWSSFVPNYNPRDIIANVRHMLRDEPMEPMDPWYKGFRGTIEKTATKEAGATY 695
            GSEGIGTGWSS++PNYNPRDI+ANVR +L  E MEPM PWY+GF+G IEKTA+KEAG TY
Sbjct: 832  GSEGIGTGWSSYIPNYNPRDIVANVRRLLNGEQMEPMHPWYRGFKGNIEKTASKEAGVTY 891

Query: 694  TVTGIIEEVSDTTLRVTELPVRKWTQDYKDFLESLY----PFIEDVREYHTTDSVNFEID 527
            T+TGIIEEV +TTLR+TELPVR+WTQDY++FLES+     PFI++ R+Y    +V FE+ 
Sbjct: 892  TITGIIEEVDETTLRITELPVRRWTQDYREFLESIITGNDPFIKEFRQYSDDTTVEFEVI 951

Query: 526  LSEENMRIAKQEGLLKKFKLTTTISTSNMHLFDSKGVIKKYDTPEKILEDFFSIRFEFYE 347
            L+EENM +AKQEGLLKKFKLTTTISTSNMHLFDSKG+IKKYDTPE+ILE+FF +RFEFYE
Sbjct: 952  LTEENMMVAKQEGLLKKFKLTTTISTSNMHLFDSKGMIKKYDTPEQILEEFFHLRFEFYE 1011

Query: 346  KRKKALMDNLERELLILENKVRFIMDVVEGKIVVSNRRRADLVLELKEKGFTPFPKKAKT 167
            KRKK L+DNLE ELL +ENKVRFI+ VV+G+I+V+NR+RADL LEL+ KGFTPFPKKAKT
Sbjct: 1012 KRKKLLLDNLEMELLKMENKVRFILGVVKGEIIVNNRKRADLFLELQTKGFTPFPKKAKT 1071

Query: 166  TEISVAGSTDVPEETEENSDMATSQGVRASDYEYLLSMSIGSLTIEKVQELCNNR 2
             E++VAG+TD  EETEENS++ +++G++ASDY+YLLSM+IGSLT+EKVQELC +R
Sbjct: 1072 VEVAVAGATDDTEETEENSEV-SAKGLQASDYDYLLSMAIGSLTLEKVQELCADR 1125


>ref|XP_007009327.1| DNA topoisomerase 2 isoform 1 [Theobroma cacao]
            gi|508726240|gb|EOY18137.1| DNA topoisomerase 2 isoform 1
            [Theobroma cacao]
          Length = 1473

 Score = 1778 bits (4606), Expect = 0.0
 Identities = 872/1135 (76%), Positives = 994/1135 (87%), Gaps = 13/1135 (1%)
 Frame = -1

Query: 3367 MAPKKAPLTSSNNANIPPEXXXXXXXXXAKTIEQTYQKKTQLEHILLRPDTYIGSIEKHN 3188
            +A  K PL SSNNAN+             KTIE+TYQKKTQLEHILLRPDTYIGSIE+H 
Sbjct: 2    VADSKLPLQSSNNANMKAS----------KTIEETYQKKTQLEHILLRPDTYIGSIEQHT 51

Query: 3187 QTLWVYEEKQMVQKPITYVPGLYKIFDEILVNAADNKQRDPKMNSLKVTIDAEANCISVY 3008
            Q LWVYE  +MV + I YVPGLYKIFDEILVNAADNKQRDP M+S+KV IDAE N ISVY
Sbjct: 52   QRLWVYENDEMVHRDIKYVPGLYKIFDEILVNAADNKQRDPSMDSVKVVIDAEQNLISVY 111

Query: 3007 NNGDGVPVEIHQEEGVYVPELIFGHLLTSSNYDDHEKKTTGGRNGYGAKLTNIFSTEFVI 2828
            NNGDGVPVE+HQEEGVYVPELIFGHLLTSSNYDD  KKTTGGRNGYGAKLTNIFSTEF+I
Sbjct: 112  NNGDGVPVEVHQEEGVYVPELIFGHLLTSSNYDDTVKKTTGGRNGYGAKLTNIFSTEFII 171

Query: 2827 ETADGRRQRKYKQVFTCNMGNKSQPVISKCKESENWTKVTFKPDLSKFNMTHLEDDVVAL 2648
            ETADG+RQ+KYKQVF+ NMG KS+PVISKCKE+ENWTKVTFKPDL+KFNMTHLE+DVVAL
Sbjct: 172  ETADGKRQKKYKQVFSNNMGKKSEPVISKCKEAENWTKVTFKPDLAKFNMTHLEEDVVAL 231

Query: 2647 MKKRVIDMAGCLGKNVKVELNGEDIRVRSFGDYCNLYLKSAF--------RIEEKV-DRW 2495
            MKKRV D+AGCLGK VKVELNG+ + V+SF DY +LYL +A         R+ EKV +RW
Sbjct: 232  MKKRVFDVAGCLGKTVKVELNGKRVPVKSFLDYVSLYLSAASKTKTEPLPRLLEKVNERW 291

Query: 2494 EVCVSLSDGQFQQVSFVNSISTIKGGTHVDYVTNQIATHLAEYVNKKRKNANLKPHSVRN 2315
            EV VSLSDGQFQQVSFVN I+TIKGGTHVDYVTNQI+ ++   VNKK KNAN+K H+V+N
Sbjct: 292  EVGVSLSDGQFQQVSFVNGIATIKGGTHVDYVTNQISNYVMNIVNKKNKNANVKAHNVKN 351

Query: 2314 HLWVFVNCLIDNPAFDSQTKETLTLRQKSFGSECKLSDKFLSKVANSEIVNNILEWAEFK 2135
            HLWVFVN LIDNPAFDSQTKETLTLRQ SFGS+C+LS+ FL KVA   +V+N+L WAEFK
Sbjct: 352  HLWVFVNALIDNPAFDSQTKETLTLRQSSFGSKCELSEDFLKKVAKCGVVDNLLSWAEFK 411

Query: 2134 EKKDLKKTDGTKSKRITGLTKLADANNAGGRNSEKCTLILTEGDSAATLAIAGLSVVGRD 1955
              KDLKKTDG K+  I G+ KL DAN AGGRNS+KCTLILTEGDSA  LA+AGL+VVGR+
Sbjct: 412  HSKDLKKTDGAKTGSIRGIPKLDDANEAGGRNSDKCTLILTEGDSAKALAVAGLAVVGRN 471

Query: 1954 HYGVFPLRGKLLNVRDASTKQINDNAEIQNIKKILGLQHGKQYDSIKSLRYGHLMIMTDQ 1775
            HYGVFPLRGKLLNVR+AS KQ+ DNAEIQN+K+ILGLQ GK+Y ++KSLRYGHLMIMTDQ
Sbjct: 472  HYGVFPLRGKLLNVREASHKQLMDNAEIQNLKRILGLQQGKEYSNVKSLRYGHLMIMTDQ 531

Query: 1774 DHDGSHIKGLLINFIHSFWPSLLRIPSFLVEFITPIVKATHKNGEKRSFYTMPEYESWKE 1595
            DHDGSHIKGLLINFIHSFWPSLL++PSF+VEFITPIVKATHK     SFY+MPEYE WKE
Sbjct: 532  DHDGSHIKGLLINFIHSFWPSLLKVPSFMVEFITPIVKATHKTKGVLSFYSMPEYEFWKE 591

Query: 1594 SLGDKARSWSIKYYKGLGTSTDKEGKEYFKDLGKHKKDFVWADDHDGEAIELAFSKKKIE 1415
            SLG  A+ WSIKYYKGLGTST KEGK+YFK+L KH+K+FVW D+ DGEAIELAFSKKKIE
Sbjct: 592  SLGGNAKGWSIKYYKGLGTSTSKEGKDYFKNLDKHRKEFVWQDEQDGEAIELAFSKKKIE 651

Query: 1414 ARKNWLRQFEPGTYLDQEDKLIKYRDFVNKELILFSIADLQRSIPSMVDGLKPGQRKILF 1235
            ARKNWLRQFEPGT+LDQ  KLIKY +F+NKELILFS+ADLQRSIPSM+DGLKPGQRKILF
Sbjct: 652  ARKNWLRQFEPGTHLDQSQKLIKYSEFINKELILFSMADLQRSIPSMIDGLKPGQRKILF 711

Query: 1234 CAFKRNFVHEAKVGQFAGYVSEHSAYHHGEQSLASTIIGMAQQYVGSNNINILKPNGQFG 1055
            C+FKRNFV EAKV QF+GYVSEHSAYHHGEQSLASTI+GMAQ +VGSNNIN+L P GQFG
Sbjct: 712  CSFKRNFVKEAKVAQFSGYVSEHSAYHHGEQSLASTIVGMAQDFVGSNNINLLNPGGQFG 771

Query: 1054 TRNQGGKDHASARYIFTQLSAITRFLFPKDDDILLDYQNEDGQTIEPTWYVPIIPVVLVN 875
            TRNQGGKD ASARYIFT LS ITR+LFPKDDD LLDY NEDGQ+IEP WYVPIIP+VLVN
Sbjct: 772  TRNQGGKDAASARYIFTNLSPITRYLFPKDDDGLLDYLNEDGQSIEPIWYVPIIPMVLVN 831

Query: 874  GSEGIGTGWSSFVPNYNPRDIIANVRHMLRDEPMEPMDPWYKGFRGTIEKTATKEAGATY 695
            GSEGIGTGWSS++PNYNPRDI+ANVR +L  E MEPM PWY+GF+G IEKTA+KEAG TY
Sbjct: 832  GSEGIGTGWSSYIPNYNPRDIVANVRRLLNGEQMEPMHPWYRGFKGNIEKTASKEAGVTY 891

Query: 694  TVTGIIEEVSDTTLRVTELPVRKWTQDYKDFLESLY----PFIEDVREYHTTDSVNFEID 527
            T+TGIIEEV +TTLR+TELPVR+WTQDY++FLES+     PFI++ R+Y    +V FE+ 
Sbjct: 892  TITGIIEEVDETTLRITELPVRRWTQDYREFLESIITGNDPFIKEFRQYSDDTTVEFEVI 951

Query: 526  LSEENMRIAKQEGLLKKFKLTTTISTSNMHLFDSKGVIKKYDTPEKILEDFFSIRFEFYE 347
            L+EENM +AKQEGLLKKFKLTTTISTSNMHLFDSKG+IKKYDTPE+ILE+FF +RFEFYE
Sbjct: 952  LTEENMMVAKQEGLLKKFKLTTTISTSNMHLFDSKGMIKKYDTPEQILEEFFHLRFEFYE 1011

Query: 346  KRKKALMDNLERELLILENKVRFIMDVVEGKIVVSNRRRADLVLELKEKGFTPFPKKAKT 167
            KRKK L+DNLE ELL +ENKVRFI+ VV+G+I+V+NR+RADL LEL+ KGFTPFPKKAKT
Sbjct: 1012 KRKKLLLDNLEMELLKMENKVRFILGVVKGEIIVNNRKRADLFLELQTKGFTPFPKKAKT 1071

Query: 166  TEISVAGSTDVPEETEENSDMATSQGVRASDYEYLLSMSIGSLTIEKVQELCNNR 2
             E++VAG+TD  EETEENS++ +++G++ASDY+YLLSM+IGSLT+EKVQELC +R
Sbjct: 1072 VEVAVAGATDDTEETEENSEV-SAKGLQASDYDYLLSMAIGSLTLEKVQELCADR 1125


>ref|XP_010257162.1| PREDICTED: LOW QUALITY PROTEIN: DNA topoisomerase 2-like [Nelumbo
            nucifera]
          Length = 1489

 Score = 1773 bits (4593), Expect = 0.0
 Identities = 868/1133 (76%), Positives = 984/1133 (86%), Gaps = 17/1133 (1%)
 Frame = -1

Query: 3358 KKAPLTSSNNANIPPEXXXXXXXXXAKTIEQTYQKKTQLEHILLRPDTYIGSIEKHNQTL 3179
            KK PL +SNN N+             KTIE+TYQKK+QLEHILLRPDTYIGSIEKH QTL
Sbjct: 5    KKFPLQTSNNVNVASSRPPVAPG---KTIEETYQKKSQLEHILLRPDTYIGSIEKHTQTL 61

Query: 3178 WVYEEKQMVQKPITYVPGLYKIFDEILVNAADNKQRDPKMNSLKVTIDAEANCISVYNNG 2999
            WVYE  +MV +P+TYVPGLYKIFDEILVNAADNKQRDP M+S+KV ID E NCISVYNNG
Sbjct: 62   WVYEGGEMVHRPVTYVPGLYKIFDEILVNAADNKQRDPSMDSVKVDIDVEQNCISVYNNG 121

Query: 2998 DGVPVEIHQEEGVYVPELIFGHLLTSSNYDDHEKKTTGGRNGYGAKLTNIFSTEFVIETA 2819
            DGVPVEIHQEEGVYVPE+IFGHLLTSSNYDD  KKTTGGRNGYGAKLTNIFSTEF+I+TA
Sbjct: 122  DGVPVEIHQEEGVYVPEMIFGHLLTSSNYDDTVKKTTGGRNGYGAKLTNIFSTEFIIQTA 181

Query: 2818 DGRRQRKYKQVFTCNMGNKSQPVISKCKESENWTKVTFKPDLSKFNMTHLEDDVVALMKK 2639
            DGRRQ+KYKQVF+ NMG KS+P I+KCKE ENWTKVTFKPDL+KFNMTHLEDDV+ALMKK
Sbjct: 182  DGRRQKKYKQVFSNNMGKKSEPTITKCKEGENWTKVTFKPDLAKFNMTHLEDDVLALMKK 241

Query: 2638 RVIDMAGCLGKNVKVELNGEDIRVRSFGDYCNLYLKSAF--------RIEEKV-DRWEVC 2486
            RVID+AGCLGK VKVELNG+ + V+SF DY NLYL+SA         RI EKV +RWE+C
Sbjct: 242  RVIDLAGCLGKTVKVELNGQRVPVKSFLDYVNLYLQSASKTRPESLPRITEKVNERWEIC 301

Query: 2485 VSLSDGQFQQVSFVNSISTIKGGTHVDYVTNQIATHLAEYVNKKRKNANLKPHSVRNHLW 2306
            VSLS+GQFQQVSFVN I+TIKGGTHVDYVTNQI  H+   VNKK KNANLK H+V+NHLW
Sbjct: 302  VSLSEGQFQQVSFVNGIATIKGGTHVDYVTNQITNHVMTIVNKKNKNANLKAHTVKNHLW 361

Query: 2305 VFVNCLIDNPAFDSQTKETLTLRQKSFGSECKLSDKFLSKVANSEIVNNILEWAEFKEKK 2126
            VFVN LIDNPAFDSQTKETLT RQ SFGS+C+LS +FL KVA S +V N+L WA+FK+ K
Sbjct: 362  VFVNALIDNPAFDSQTKETLTTRQNSFGSKCELSQEFLKKVAKSGVVENLLSWADFKQSK 421

Query: 2125 DLKKTDGTKSKRITGLTKLADANNAGGRNSEKCTLILTEGDSAATLAIAGLSVVGRDHYG 1946
            DLKKTDG K +RITG+TKL DAN+AGG+NSEKCTLILTEGDSA  LA+AG+SVVGR+HYG
Sbjct: 422  DLKKTDGAKRQRITGITKLEDANDAGGKNSEKCTLILTEGDSAKALAMAGISVVGRNHYG 481

Query: 1945 VFPLRGKLLNVRDASTKQINDNAEIQNIKKILGLQHGKQYDSIKSLRYGHLMIMTDQDHD 1766
            VFPLRGKLLNVR+A+ KQI +NAEIQNIK+ILGLQHGK+YDS+KSLRYGHLMIMTDQDHD
Sbjct: 482  VFPLRGKLLNVREANHKQIMENAEIQNIKQILGLQHGKEYDSVKSLRYGHLMIMTDQDHD 541

Query: 1765 GSHIKGLLINFIHSFWPSLLRIPSFLVEFITPIVKATHKNGEKRSFYTMPEYESWKESLG 1586
            GSHIKGLLINFIH+FWPSLL+IPSFLVEFITP+VKA HKNG   SFY+MPEYESWKESL 
Sbjct: 542  GSHIKGLLINFIHTFWPSLLKIPSFLVEFITPVVKAIHKNGRVLSFYSMPEYESWKESLA 601

Query: 1585 DKARSWSIKYYKGLGTSTDKEGKEYFKDLGKHKKDFVWADDHDGEAIELAFSKKKIEARK 1406
              A  WSIKYYKGLGTST KEGKEYFKDL  HKKDF+W ++ DG+AIELAFSKKKIEARK
Sbjct: 602  GNASGWSIKYYKGLGTSTSKEGKEYFKDLDMHKKDFIWINEQDGDAIELAFSKKKIEARK 661

Query: 1405 NWLRQFEPGTYLDQEDKLIKYRDFVNKELILFSIADLQRSIPSMVDGLKPGQRKILFCAF 1226
            NWLR FEPGTYLDQ++K IKY DFVNKELILFS+ADLQRSIPSMVDGLKPGQRKILFCAF
Sbjct: 662  NWLRNFEPGTYLDQKEKFIKYSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKILFCAF 721

Query: 1225 KRNFVHEAKVGQFAGYVSEHSAYHHGEQSLASTIIGMAQQYVGSNNINILKPNGQFGTRN 1046
            KRNF+ EAKV QF+GYVSEHSAYHHGEQSL STIIGMAQ YVGSNNIN+ +PNGQFGTR+
Sbjct: 722  KRNFIKEAKVAQFSGYVSEHSAYHHGEQSLMSTIIGMAQDYVGSNNINLFQPNGQFGTRH 781

Query: 1045 QGGKDHASARYIFTQLSAITRFLFPKDDDILLDYQNEDGQTIEPTWYVPIIPVVLVNGSE 866
            QGGKDHASARYI+T+LS ITRFLFPKDDDILLDY NEDGQ+IEPTWY+PI+P+VLVNGSE
Sbjct: 782  QGGKDHASARYIYTRLSPITRFLFPKDDDILLDYLNEDGQSIEPTWYMPIVPMVLVNGSE 841

Query: 865  GIGTGWSSFVPNYNPRDIIANVRHMLRDEPMEPMDPWYKGFRGTIEKTATKEAGATYTVT 686
            GIGTGWSS++PNYNPRDI+AN+R +L  EPME MDPWYKGFRG IEKTATKEAG++YTV+
Sbjct: 842  GIGTGWSSYIPNYNPRDIVANIRRLLNGEPMEAMDPWYKGFRGLIEKTATKEAGSSYTVS 901

Query: 685  GIIEEVSDTTLRVTELPVRKWTQDYKDFLESLY--------PFIEDVREYHTTDSVNFEI 530
            GIIE+  D                 K+FLES+         PFI+D RE++   +V+FE+
Sbjct: 902  GIIEDXDD-----------------KEFLESIMTGNDKIKEPFIKDYREHNDDTTVHFEV 944

Query: 529  DLSEENMRIAKQEGLLKKFKLTTTISTSNMHLFDSKGVIKKYDTPEKILEDFFSIRFEFY 350
             LSEEN++ AKQEGL+KKFKLTTTISTSNMHLFD KGVIKKYD PE+ILE+FF +R EFY
Sbjct: 945  ILSEENLQAAKQEGLMKKFKLTTTISTSNMHLFDPKGVIKKYDNPEQILEEFFHLRLEFY 1004

Query: 349  EKRKKALMDNLERELLILENKVRFIMDVVEGKIVVSNRRRADLVLELKEKGFTPFPKKAK 170
            EKRKK L+DNLE +LL L+NKVRFI+ VV+G+I+VSNR+RADL LEL++KGFTPFPKK K
Sbjct: 1005 EKRKKVLLDNLELDLLKLDNKVRFILGVVKGEIIVSNRKRADLFLELQQKGFTPFPKKTK 1064

Query: 169  TTEISVAGSTDVPEETEENSDMATSQGVRASDYEYLLSMSIGSLTIEKVQELC 11
            T E++VAG+T+  EE EENS++ +S+GVRASDYEYLLSM+IG+LT+EKVQELC
Sbjct: 1065 TVEVAVAGATEDAEENEENSEVVSSKGVRASDYEYLLSMAIGTLTLEKVQELC 1117


>ref|XP_010920068.1| PREDICTED: DNA topoisomerase 2 [Elaeis guineensis]
          Length = 1486

 Score = 1759 bits (4556), Expect = 0.0
 Identities = 862/1137 (75%), Positives = 985/1137 (86%), Gaps = 18/1137 (1%)
 Frame = -1

Query: 3358 KKAPLTSSNNANIPPEXXXXXXXXXAKTIEQTYQKKTQLEHILLRPDTYIGSIEKHNQTL 3179
            KK PL SS   N              KTIE+ YQKKTQLEHILLRPDTYIGS+EKH QTL
Sbjct: 5    KKQPLQSSTAYN-SAAGGGATANGPNKTIEEMYQKKTQLEHILLRPDTYIGSVEKHTQTL 63

Query: 3178 WVYEEKQMVQKPITYVPGLYKIFDEILVNAADNKQRDPKMNSLKVTIDAEANCISVYNNG 2999
            WVYE  +MV +P+TYVPGLYKIFDEILVNAADNKQRDP M+S+KV ID   NCISVYN+G
Sbjct: 64   WVYENGEMVHRPVTYVPGLYKIFDEILVNAADNKQRDPSMDSVKVEIDVAGNCISVYNSG 123

Query: 2998 DGVPVEIHQEEGVYVPELIFGHLLTSSNYDDHEKKTTGGRNGYGAKLTNIFSTEFVIETA 2819
            DG+PVEIHQEEGVYVPE+IFGHLLTSSNYDD+ KKTTGGRNGYGAKLTNIFSTEFVI+TA
Sbjct: 124  DGIPVEIHQEEGVYVPEMIFGHLLTSSNYDDNVKKTTGGRNGYGAKLTNIFSTEFVIQTA 183

Query: 2818 DGRRQRKYKQVFTCNMGNKSQPVISKCKESENWTKVTFKPDLSKFNMTHLEDDVVALMKK 2639
            DGRRQ+KYKQVF+ NMG KS+P I KCKE ENWTKVTFKPDL+KFNMTHLEDDVVALMKK
Sbjct: 184  DGRRQKKYKQVFSENMGKKSEPSIVKCKEGENWTKVTFKPDLAKFNMTHLEDDVVALMKK 243

Query: 2638 RVIDMAGCLGKNVKVELNGEDIRVRSFGDYCNLYLKSAF--------RIEEKV-DRWEVC 2486
            RV+D+AG LGK+VKVELNG+ I V+SFGDY NLYL+SA         RI EKV DRWE+C
Sbjct: 244  RVVDLAGILGKSVKVELNGQRIPVKSFGDYVNLYLQSASKSRPEPLPRISEKVNDRWEIC 303

Query: 2485 VSLSDGQFQQVSFVNSISTIKGGTHVDYVTNQIATHLAEYVNKKRKNANLKPHSVRNHLW 2306
             SLS+GQFQQVSFVN I+T+KGGTHV+YVTNQI +H+   VNKK KNANLK H+VR+HLW
Sbjct: 304  ASLSEGQFQQVSFVNGIATVKGGTHVEYVTNQITSHVMSIVNKKNKNANLKAHNVRSHLW 363

Query: 2305 VFVNCLIDNPAFDSQTKETLTLRQKSFGSECKLSDKFLSKVANSEIVNNILEWAEFKEKK 2126
            VFVN LIDNPAFDSQTKETLT RQ SFGS+C+LS +FL KVA S +VN++L WA+FK+ K
Sbjct: 364  VFVNALIDNPAFDSQTKETLTTRQGSFGSKCELSQEFLKKVAKSGVVNSLLSWADFKQSK 423

Query: 2125 DLKKTDGTKSKRITGLTKLADANNAGGRNSEKCTLILTEGDSAATLAIAGLSVVGRDHYG 1946
            +LKKTDGTK +RI G+ KL DAN+AGGRNSEKCTLILTEGDSA  LA+AG+SVVGR+HYG
Sbjct: 424  ELKKTDGTKRQRIVGIPKLEDANDAGGRNSEKCTLILTEGDSAKALAMAGISVVGRNHYG 483

Query: 1945 VFPLRGKLLNVRDASTKQINDNAEIQNIKKILGLQHGKQYDSIKSLRYGHLMIMTDQDHD 1766
            VFPLRGKLLNVR+AS KQI DNAEIQ+IK+ILGLQ GK+Y+S K LRYGHLMIMTDQDHD
Sbjct: 484  VFPLRGKLLNVREASHKQIMDNAEIQSIKQILGLQQGKEYESTKGLRYGHLMIMTDQDHD 543

Query: 1765 GSHIKGLLINFIHSFWPSLLRIPSFLVEFITPIVKATH-KNGEKRSFYTMPEYESWKESL 1589
            GSHIKGLLINFIHSFWPSLL+IPSF+VEFITPIVKATH +N     FY+MPEYE+WKESL
Sbjct: 544  GSHIKGLLINFIHSFWPSLLKIPSFMVEFITPIVKATHNRNKNVLPFYSMPEYEAWKESL 603

Query: 1588 GDKARSWSIKYYKGLGTSTDKEGKEYFKDLGKHKKDFVWADDHDGEAIELAFSKKKIEAR 1409
            G  A  WSIKYYKGLGTST KEGKEYF+D+ KHKKDF+W D+ DG+AIELAFSKKKIEAR
Sbjct: 604  GGNASGWSIKYYKGLGTSTSKEGKEYFQDIVKHKKDFMWVDNQDGDAIELAFSKKKIEAR 663

Query: 1408 KNWLRQFEPGTYLDQEDKLIKYRDFVNKELILFSIADLQRSIPSMVDGLKPGQRKILFCA 1229
            KNWLRQFEPGTYLDQ +KLIKY DFVNKELILFS+ADLQRSIPSMVDGLKPGQRKILFC+
Sbjct: 664  KNWLRQFEPGTYLDQREKLIKYSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKILFCS 723

Query: 1228 FKRNFVHEAKVGQFAGYVSEHSAYHHGEQSLASTIIGMAQQYVGSNNINILKPNGQFGTR 1049
            FKRNFV EAKV QFAGYVSEHSAYHHGEQSLASTIIGMAQ +VGSNNIN+L+PNGQFGTR
Sbjct: 724  FKRNFVKEAKVAQFAGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLQPNGQFGTR 783

Query: 1048 NQGGKDHASARYIFTQLSAITRFLFPKDDDILLDYQNEDGQTIEPTWYVPIIPVVLVNGS 869
            +QGGKDHASARYI+T+LS +TRFLFPKDDDILLDY NEDGQ IEPTWY+PIIP+VLVNGS
Sbjct: 784  HQGGKDHASARYIYTRLSPLTRFLFPKDDDILLDYLNEDGQLIEPTWYMPIIPMVLVNGS 843

Query: 868  EGIGTGWSSFVPNYNPRDIIANVRHMLRDEPMEPMDPWYKGFRGTIEKTATKEAGATYTV 689
            EGIGTGWS+FVPNYNPRDI+ANVR +L +EPM+PMDPWY+ F+G IEK+A+KEAG TYT+
Sbjct: 844  EGIGTGWSTFVPNYNPRDIVANVRRLLNNEPMQPMDPWYRSFKGLIEKSASKEAGVTYTI 903

Query: 688  TGIIEEVSDTTLRVTELPVRKWTQDYKDFLESLY--------PFIEDVREYHTTDSVNFE 533
            TG+ EEV  TTL++TELP+R+WTQDYK+FLESL         PFI+D RE +   +V+FE
Sbjct: 904  TGLAEEVDSTTLKITELPIRRWTQDYKEFLESLMTGNDKIKEPFIKDYREQNDDVNVHFE 963

Query: 532  IDLSEENMRIAKQEGLLKKFKLTTTISTSNMHLFDSKGVIKKYDTPEKILEDFFSIRFEF 353
            I L+EE + +A++EGL KKFKLTTTIST+NMHLFDSKGVIKKYDTPE+ILEDFF +R EF
Sbjct: 964  IILTEEKLNMAREEGLEKKFKLTTTISTTNMHLFDSKGVIKKYDTPEQILEDFFHLRLEF 1023

Query: 352  YEKRKKALMDNLERELLILENKVRFIMDVVEGKIVVSNRRRADLVLELKEKGFTPFPKKA 173
            Y KRKKAL+DNLE +LL L+NKVRFI+ VV G+I+V+NR+RADL LEL++KGF PFPKK+
Sbjct: 1024 YAKRKKALLDNLELDLLKLDNKVRFILGVVRGEIIVNNRKRADLFLELQQKGFAPFPKKS 1083

Query: 172  KTTEISVAGSTDVPEETEENSDMATSQGVRASDYEYLLSMSIGSLTIEKVQELCNNR 2
            K  + ++AG+T   +  EE+ ++    G RA+DYEYLLSM+IG+LT EKVQELC  R
Sbjct: 1084 KGIDAAIAGATVEEDGNEESPEVVNGGGARAADYEYLLSMAIGTLTWEKVQELCAER 1140


>ref|XP_011621441.1| PREDICTED: DNA topoisomerase 2 [Amborella trichopoda]
          Length = 1504

 Score = 1748 bits (4528), Expect = 0.0
 Identities = 853/1134 (75%), Positives = 985/1134 (86%), Gaps = 18/1134 (1%)
 Frame = -1

Query: 3358 KKAPLTSSNNANI-PPEXXXXXXXXXAKTIEQTYQKKTQLEHILLRPDTYIGSIEKHNQT 3182
            KK PL +S+N N               KTIE+TYQKKTQLEHILLRPDTYIGS+EKH Q 
Sbjct: 6    KKKPLETSSNFNSNAANLTTINGSKPGKTIEETYQKKTQLEHILLRPDTYIGSVEKHTQN 65

Query: 3181 LWVYEEKQMVQKPITYVPGLYKIFDEILVNAADNKQRDPKMNSLKVTIDAEANCISVYNN 3002
            LWVYEE +MV + I+YVPGLYKIFDEILVNAADNKQRDP M+SLKV ID E N +SVYNN
Sbjct: 66   LWVYEENKMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMDSLKVDIDVEQNTVSVYNN 125

Query: 3001 GDGVPVEIHQEEGVYVPELIFGHLLTSSNYDDHEKKTTGGRNGYGAKLTNIFSTEFVIET 2822
            GDGVPVEIHQEEGVYVPE+IFGHLLTSSNY+D  KKTTGGRNGYGAKLTNIFST+FVIET
Sbjct: 126  GDGVPVEIHQEEGVYVPEMIFGHLLTSSNYNDEVKKTTGGRNGYGAKLTNIFSTQFVIET 185

Query: 2821 ADGRRQRKYKQVFTCNMGNKSQPVISKCKESENWTKVTFKPDLSKFNMTHLEDDVVALMK 2642
            ADG+RQ+KYKQVFT NMG+KS+P I+KCK  ENWTKVTFKPDL+KFNMT+LE+DVVALMK
Sbjct: 186  ADGKRQKKYKQVFTSNMGSKSEPAITKCKAGENWTKVTFKPDLAKFNMTYLEEDVVALMK 245

Query: 2641 KRVIDMAGCLGKNVKVELNGEDIRVRSFGDYCNLYLKSAF--------RIEEKVD-RWEV 2489
            KRV+D+AGCLGK VKVELNG+ + V+SF DY +LY+KSA         RI EKV+ RWE+
Sbjct: 246  KRVVDLAGCLGKTVKVELNGKRLPVKSFVDYVDLYVKSASEARPEPLPRIVEKVNNRWEI 305

Query: 2488 CVSLSDGQFQQVSFVNSISTIKGGTHVDYVTNQIATHLAEYVNKKRKNANLKPHSVRNHL 2309
            CVSLS+GQFQQVSFVN I+TIKGGTHV+YVT QIA H+    NKK KNA +K H+VRNHL
Sbjct: 306  CVSLSEGQFQQVSFVNGIATIKGGTHVEYVTGQIANHIMNIANKKNKNAGIKAHTVRNHL 365

Query: 2308 WVFVNCLIDNPAFDSQTKETLTLRQKSFGSECKLSDKFLSKVANSEIVNNILEWAEFKEK 2129
            WVFVN LIDNPAFDSQTKETLT RQ SFGS+C+LS++FL K ANS IV ++L WA+FK+ 
Sbjct: 366  WVFVNALIDNPAFDSQTKETLTTRQGSFGSKCELSEEFLKKAANSGIVESLLSWADFKQS 425

Query: 2128 KDLKKTDGTKSKRITGLTKLADANNAGGRNSEKCTLILTEGDSAATLAIAGLSVVGRDHY 1949
            KDLKKTDGTK +RITGL KL DAN AGGRNSEKCTLILTEGDSA  LA+AG+SVVGRDH+
Sbjct: 426  KDLKKTDGTKCQRITGLPKLEDANQAGGRNSEKCTLILTEGDSAKALAMAGISVVGRDHF 485

Query: 1948 GVFPLRGKLLNVRDASTKQINDNAEIQNIKKILGLQHGKQYDSIKSLRYGHLMIMTDQDH 1769
            GVFPLRGKLLNVR+A+  QI DN EIQNIK+ILGLQHGK YDS+KSLRYGHLMIMTDQDH
Sbjct: 486  GVFPLRGKLLNVREATKTQIKDNKEIQNIKQILGLQHGKVYDSVKSLRYGHLMIMTDQDH 545

Query: 1768 DGSHIKGLLINFIHSFWPSLLRIPSFLVEFITPIVKATHKNGEKRSFYTMPEYESWKESL 1589
            DGSHIKGLLINFIHSFWPSLL++PSFLVEFITPIVKA +KNG+  SFYT+PEYESWKESL
Sbjct: 546  DGSHIKGLLINFIHSFWPSLLKVPSFLVEFITPIVKARNKNGKVLSFYTLPEYESWKESL 605

Query: 1588 GDKARSWSIKYYKGLGTSTDKEGKEYFKDLGKHKKDFVWADDHDGEAIELAFSKKKIEAR 1409
            G  AR W+IKYYKGLGTST +EGKEYFK++ KHKKDF+W DD DG+AIELAFSKKKIEAR
Sbjct: 606  GGNARGWTIKYYKGLGTSTSQEGKEYFKEINKHKKDFIWVDDQDGDAIELAFSKKKIEAR 665

Query: 1408 KNWLRQFEPGTYLDQEDKLIKYRDFVNKELILFSIADLQRSIPSMVDGLKPGQRKILFCA 1229
            KNWLR FEPGTYLDQ++KLIKY DFVNKELILFS+ADLQRSIPSMVDGLKPGQRKILFC+
Sbjct: 666  KNWLRHFEPGTYLDQKEKLIKYSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKILFCS 725

Query: 1228 FKRNFVHEAKVGQFAGYVSEHSAYHHGEQSLASTIIGMAQQYVGSNNINILKPNGQFGTR 1049
            FKRNFV +AKV QF+GYVSEHSAYHHGEQSLA+TI+GMAQ +VG+NNIN+L+P GQFGTR
Sbjct: 726  FKRNFVSQAKVVQFSGYVSEHSAYHHGEQSLAATIVGMAQDFVGTNNINLLQPLGQFGTR 785

Query: 1048 NQGGKDHASARYIFTQLSAITRFLFPKDDDILLDYQNEDGQTIEPTWYVPIIPVVLVNGS 869
            N+GGKD ASARYIFT LS ITRFLFPKDDD+LLDYQNEDGQ IEP WY+PIIP+VL+NGS
Sbjct: 786  NRGGKDAASARYIFTCLSPITRFLFPKDDDVLLDYQNEDGQCIEPNWYMPIIPLVLINGS 845

Query: 868  EGIGTGWSSFVPNYNPRDIIANVRHMLRDEPMEPMDPWYKGFRGTIEKTATKEAGATYTV 689
            EGIGTGWSS+VPNYNPRD+ ANV+ +L  E M PM+PWYKGF+GTIEK+ATKE G  YTV
Sbjct: 846  EGIGTGWSSYVPNYNPRDVAANVKRLLNGESMLPMEPWYKGFKGTIEKSATKEGGVGYTV 905

Query: 688  TGIIEEVSDTTLRVTELPVRKWTQDYKDFLESL--------YPFIEDVREYHTTDSVNFE 533
            +GI+EE+++TTLR+TELP+R+WT+DYK +LESL         PFI D +E++T   V+F+
Sbjct: 906  SGIVEEINETTLRITELPIRRWTEDYKVYLESLRTGSEKTKEPFIVDYKEHNTDTRVHFD 965

Query: 532  IDLSEENMRIAKQEGLLKKFKLTTTISTSNMHLFDSKGVIKKYDTPEKILEDFFSIRFEF 353
            + L EENM+I++QEGL+K FKLTTTISTSNMHLF++KGVIKKYDTPE+ILE+FF +R ++
Sbjct: 966  VLLPEENMKISQQEGLMKMFKLTTTISTSNMHLFNAKGVIKKYDTPEQILEEFFHLRLDY 1025

Query: 352  YEKRKKALMDNLERELLILENKVRFIMDVVEGKIVVSNRRRADLVLELKEKGFTPFPKKA 173
            Y KRKK L+DNLE ELL L+NK RFI+ VV G+IVVS R+RADLVLEL++KGFTPFPKK+
Sbjct: 1026 YGKRKKVLLDNLELELLKLDNKARFILGVVNGEIVVSKRKRADLVLELRDKGFTPFPKKS 1085

Query: 172  KTTEISVAGSTDVPEETEENSDMATSQGVRASDYEYLLSMSIGSLTIEKVQELC 11
            K  E ++AG+T V EE EE+ ++   +G+ ASDY+YLLSM+IG+LTIEKVQELC
Sbjct: 1086 KNVEAALAGATPVDEEGEESPEV-DDRGINASDYDYLLSMAIGTLTIEKVQELC 1138


>gb|ERN00852.1| hypothetical protein AMTR_s00103p00101630 [Amborella trichopoda]
          Length = 1505

 Score = 1748 bits (4528), Expect = 0.0
 Identities = 853/1134 (75%), Positives = 985/1134 (86%), Gaps = 18/1134 (1%)
 Frame = -1

Query: 3358 KKAPLTSSNNANI-PPEXXXXXXXXXAKTIEQTYQKKTQLEHILLRPDTYIGSIEKHNQT 3182
            KK PL +S+N N               KTIE+TYQKKTQLEHILLRPDTYIGS+EKH Q 
Sbjct: 6    KKKPLETSSNFNSNAANLTTINGSKPGKTIEETYQKKTQLEHILLRPDTYIGSVEKHTQN 65

Query: 3181 LWVYEEKQMVQKPITYVPGLYKIFDEILVNAADNKQRDPKMNSLKVTIDAEANCISVYNN 3002
            LWVYEE +MV + I+YVPGLYKIFDEILVNAADNKQRDP M+SLKV ID E N +SVYNN
Sbjct: 66   LWVYEENKMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMDSLKVDIDVEQNTVSVYNN 125

Query: 3001 GDGVPVEIHQEEGVYVPELIFGHLLTSSNYDDHEKKTTGGRNGYGAKLTNIFSTEFVIET 2822
            GDGVPVEIHQEEGVYVPE+IFGHLLTSSNY+D  KKTTGGRNGYGAKLTNIFST+FVIET
Sbjct: 126  GDGVPVEIHQEEGVYVPEMIFGHLLTSSNYNDEVKKTTGGRNGYGAKLTNIFSTQFVIET 185

Query: 2821 ADGRRQRKYKQVFTCNMGNKSQPVISKCKESENWTKVTFKPDLSKFNMTHLEDDVVALMK 2642
            ADG+RQ+KYKQVFT NMG+KS+P I+KCK  ENWTKVTFKPDL+KFNMT+LE+DVVALMK
Sbjct: 186  ADGKRQKKYKQVFTSNMGSKSEPAITKCKAGENWTKVTFKPDLAKFNMTYLEEDVVALMK 245

Query: 2641 KRVIDMAGCLGKNVKVELNGEDIRVRSFGDYCNLYLKSAF--------RIEEKVD-RWEV 2489
            KRV+D+AGCLGK VKVELNG+ + V+SF DY +LY+KSA         RI EKV+ RWE+
Sbjct: 246  KRVVDLAGCLGKTVKVELNGKRLPVKSFVDYVDLYVKSASEARPEPLPRIVEKVNNRWEI 305

Query: 2488 CVSLSDGQFQQVSFVNSISTIKGGTHVDYVTNQIATHLAEYVNKKRKNANLKPHSVRNHL 2309
            CVSLS+GQFQQVSFVN I+TIKGGTHV+YVT QIA H+    NKK KNA +K H+VRNHL
Sbjct: 306  CVSLSEGQFQQVSFVNGIATIKGGTHVEYVTGQIANHIMNIANKKNKNAGIKAHTVRNHL 365

Query: 2308 WVFVNCLIDNPAFDSQTKETLTLRQKSFGSECKLSDKFLSKVANSEIVNNILEWAEFKEK 2129
            WVFVN LIDNPAFDSQTKETLT RQ SFGS+C+LS++FL K ANS IV ++L WA+FK+ 
Sbjct: 366  WVFVNALIDNPAFDSQTKETLTTRQGSFGSKCELSEEFLKKAANSGIVESLLSWADFKQS 425

Query: 2128 KDLKKTDGTKSKRITGLTKLADANNAGGRNSEKCTLILTEGDSAATLAIAGLSVVGRDHY 1949
            KDLKKTDGTK +RITGL KL DAN AGGRNSEKCTLILTEGDSA  LA+AG+SVVGRDH+
Sbjct: 426  KDLKKTDGTKCQRITGLPKLEDANQAGGRNSEKCTLILTEGDSAKALAMAGISVVGRDHF 485

Query: 1948 GVFPLRGKLLNVRDASTKQINDNAEIQNIKKILGLQHGKQYDSIKSLRYGHLMIMTDQDH 1769
            GVFPLRGKLLNVR+A+  QI DN EIQNIK+ILGLQHGK YDS+KSLRYGHLMIMTDQDH
Sbjct: 486  GVFPLRGKLLNVREATKTQIKDNKEIQNIKQILGLQHGKVYDSVKSLRYGHLMIMTDQDH 545

Query: 1768 DGSHIKGLLINFIHSFWPSLLRIPSFLVEFITPIVKATHKNGEKRSFYTMPEYESWKESL 1589
            DGSHIKGLLINFIHSFWPSLL++PSFLVEFITPIVKA +KNG+  SFYT+PEYESWKESL
Sbjct: 546  DGSHIKGLLINFIHSFWPSLLKVPSFLVEFITPIVKARNKNGKVLSFYTLPEYESWKESL 605

Query: 1588 GDKARSWSIKYYKGLGTSTDKEGKEYFKDLGKHKKDFVWADDHDGEAIELAFSKKKIEAR 1409
            G  AR W+IKYYKGLGTST +EGKEYFK++ KHKKDF+W DD DG+AIELAFSKKKIEAR
Sbjct: 606  GGNARGWTIKYYKGLGTSTSQEGKEYFKEINKHKKDFIWVDDQDGDAIELAFSKKKIEAR 665

Query: 1408 KNWLRQFEPGTYLDQEDKLIKYRDFVNKELILFSIADLQRSIPSMVDGLKPGQRKILFCA 1229
            KNWLR FEPGTYLDQ++KLIKY DFVNKELILFS+ADLQRSIPSMVDGLKPGQRKILFC+
Sbjct: 666  KNWLRHFEPGTYLDQKEKLIKYSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKILFCS 725

Query: 1228 FKRNFVHEAKVGQFAGYVSEHSAYHHGEQSLASTIIGMAQQYVGSNNINILKPNGQFGTR 1049
            FKRNFV +AKV QF+GYVSEHSAYHHGEQSLA+TI+GMAQ +VG+NNIN+L+P GQFGTR
Sbjct: 726  FKRNFVSQAKVVQFSGYVSEHSAYHHGEQSLAATIVGMAQDFVGTNNINLLQPLGQFGTR 785

Query: 1048 NQGGKDHASARYIFTQLSAITRFLFPKDDDILLDYQNEDGQTIEPTWYVPIIPVVLVNGS 869
            N+GGKD ASARYIFT LS ITRFLFPKDDD+LLDYQNEDGQ IEP WY+PIIP+VL+NGS
Sbjct: 786  NRGGKDAASARYIFTCLSPITRFLFPKDDDVLLDYQNEDGQCIEPNWYMPIIPLVLINGS 845

Query: 868  EGIGTGWSSFVPNYNPRDIIANVRHMLRDEPMEPMDPWYKGFRGTIEKTATKEAGATYTV 689
            EGIGTGWSS+VPNYNPRD+ ANV+ +L  E M PM+PWYKGF+GTIEK+ATKE G  YTV
Sbjct: 846  EGIGTGWSSYVPNYNPRDVAANVKRLLNGESMLPMEPWYKGFKGTIEKSATKEGGVGYTV 905

Query: 688  TGIIEEVSDTTLRVTELPVRKWTQDYKDFLESL--------YPFIEDVREYHTTDSVNFE 533
            +GI+EE+++TTLR+TELP+R+WT+DYK +LESL         PFI D +E++T   V+F+
Sbjct: 906  SGIVEEINETTLRITELPIRRWTEDYKVYLESLRTGSEKTKEPFIVDYKEHNTDTRVHFD 965

Query: 532  IDLSEENMRIAKQEGLLKKFKLTTTISTSNMHLFDSKGVIKKYDTPEKILEDFFSIRFEF 353
            + L EENM+I++QEGL+K FKLTTTISTSNMHLF++KGVIKKYDTPE+ILE+FF +R ++
Sbjct: 966  VLLPEENMKISQQEGLMKMFKLTTTISTSNMHLFNAKGVIKKYDTPEQILEEFFHLRLDY 1025

Query: 352  YEKRKKALMDNLERELLILENKVRFIMDVVEGKIVVSNRRRADLVLELKEKGFTPFPKKA 173
            Y KRKK L+DNLE ELL L+NK RFI+ VV G+IVVS R+RADLVLEL++KGFTPFPKK+
Sbjct: 1026 YGKRKKVLLDNLELELLKLDNKARFILGVVNGEIVVSKRKRADLVLELRDKGFTPFPKKS 1085

Query: 172  KTTEISVAGSTDVPEETEENSDMATSQGVRASDYEYLLSMSIGSLTIEKVQELC 11
            K  E ++AG+T V EE EE+ ++   +G+ ASDY+YLLSM+IG+LTIEKVQELC
Sbjct: 1086 KNVEAALAGATPVDEEGEESPEV-DDRGINASDYDYLLSMAIGTLTIEKVQELC 1138


>ref|XP_010023678.1| PREDICTED: DNA topoisomerase 2-like [Eucalyptus grandis]
            gi|629094018|gb|KCW60013.1| hypothetical protein
            EUGRSUZ_H02748 [Eucalyptus grandis]
          Length = 1496

 Score = 1746 bits (4523), Expect = 0.0
 Identities = 864/1146 (75%), Positives = 978/1146 (85%), Gaps = 30/1146 (2%)
 Frame = -1

Query: 3349 PLTSSNNANIPPEXXXXXXXXXAKTIEQTYQKKTQLEHILLRPDTYIGSIEKHNQTLWVY 3170
            PL +SN AN              KT+E+TYQKK+QLEHILLRPDTYIGS+EKH Q+LW+Y
Sbjct: 6    PLQTSNIANTAAAAAAPAAGRKGKTVEETYQKKSQLEHILLRPDTYIGSVEKHTQSLWIY 65

Query: 3169 EEK-----------QMVQKPITYVPGLYKIFDEILVNAADNKQRDPKMNSLKVTIDAEAN 3023
            +             +MV +PITYVPGLYKIFDEILVNAADNKQRDP+M+SLKVTIDA+ N
Sbjct: 66   DVGGDGGDGGGGGGEMVHRPITYVPGLYKIFDEILVNAADNKQRDPRMDSLKVTIDADRN 125

Query: 3022 CISVYNNGDGVPVEIHQEEGVYVPELIFGHLLTSSNYDDHEKKTTGGRNGYGAKLTNIFS 2843
             ISVYNNGDGVPVE+H+EE VYVPELIFGHLLTSSNYDD+ KKTTGGRNGYGAKLTNIFS
Sbjct: 126  LISVYNNGDGVPVEMHREEHVYVPELIFGHLLTSSNYDDNVKKTTGGRNGYGAKLTNIFS 185

Query: 2842 TEFVIETADGRRQRKYKQVFTCNMGNKSQPVISKCKESENWTKVTFKPDLSKFNMTHLED 2663
            TEFVIETADG+   KYKQVF+ NMG K  P I  CK SENWTKV+FKPDL+KFNMTHLED
Sbjct: 186  TEFVIETADGKNGLKYKQVFSKNMGVKGAPDIKACKASENWTKVSFKPDLAKFNMTHLED 245

Query: 2662 DVVALMKKRVIDMAGCLGKNVKVELNGEDIRVRSFGDYCNLYLKSAF---------RIEE 2510
            DVVALMKKRVIDMAGCLGK VKVELNG+ + V++F +Y  LYLKSA          RIEE
Sbjct: 246  DVVALMKKRVIDMAGCLGKTVKVELNGKRVPVKTFAEYVGLYLKSASKNRPECPLPRIEE 305

Query: 2509 KV-DRWEVCVSLSDGQFQQVSFVNSISTIKGGTHVDYVTNQIATHLAEYVNKKRKNANLK 2333
             V DRWEVCVSLSDGQFQQVSF N+I+TIKGGTHVDYVTNQIA H+   VNKK KNANLK
Sbjct: 306  TVNDRWEVCVSLSDGQFQQVSFANAIATIKGGTHVDYVTNQIANHVMSVVNKKNKNANLK 365

Query: 2332 PHSVRNHLWVFVNCLIDNPAFDSQTKETLTLRQKSFGSECKLSDKFLSKVANSEIVNNIL 2153
             H+V++HLWVFVN LIDNPAFDSQTKETLTLRQ SFGS+C+LSDKFL KV  S IV ++L
Sbjct: 366  AHNVKSHLWVFVNALIDNPAFDSQTKETLTLRQSSFGSKCELSDKFLQKVVKSGIVESLL 425

Query: 2152 EWAEFKEKKDLKKTDGTKSKRITGLTKLADANNAGGRNSEKCTLILTEGDSAATLAIAGL 1973
             WA FK  KDLKKTDG+K + + G+ KL DAN+AGGRNS+KCTLILTEGDSA  LA+AGL
Sbjct: 426  SWANFKLSKDLKKTDGSKRENLRGIPKLEDANDAGGRNSDKCTLILTEGDSAKALAMAGL 485

Query: 1972 SVVGRDHYGVFPLRGKLLNVRDASTKQINDNAEIQNIKKILGLQHGKQYDSIKSLRYGHL 1793
            SVVGRD YGVFPLRGKLLNVR+AS  QI +N EIQ IK+ILGLQ  K YDS+KSLRYGHL
Sbjct: 486  SVVGRDRYGVFPLRGKLLNVREASHSQIMENKEIQYIKQILGLQQNKDYDSVKSLRYGHL 545

Query: 1792 MIMTDQDHDGSHIKGLLINFIHSFWPSLLRIPSFLVEFITPIVKATHKNGEKRSFYTMPE 1613
            MIMTDQDHDGSHIKGLLINF+HSFWPSLL++PSFLVEFITPIVKATHKNG + SFYTMPE
Sbjct: 546  MIMTDQDHDGSHIKGLLINFVHSFWPSLLKVPSFLVEFITPIVKATHKNGRELSFYTMPE 605

Query: 1612 YESWKESLGDKARSWSIKYYKGLGTSTDKEGKEYFKDLGKHKKDFVWADDHDGEAIELAF 1433
            YESWKESLG     WSIKYYKGLGTST KEGK+YF++L  HKKDFVW DD DG+AIELAF
Sbjct: 606  YESWKESLGGSGSGWSIKYYKGLGTSTSKEGKQYFQNLDMHKKDFVWVDDQDGDAIELAF 665

Query: 1432 SKKKIEARKNWLRQFEPGTYLDQEDKLIKYRDFVNKELILFSIADLQRSIPSMVDGLKPG 1253
            SKKKIEARK WLRQFEPGTYLDQ++KLIKY DFVNKELILFS+ADLQRSIPSMVDGLKPG
Sbjct: 666  SKKKIEARKTWLRQFEPGTYLDQKEKLIKYSDFVNKELILFSMADLQRSIPSMVDGLKPG 725

Query: 1252 QRKILFCAFKRNFVHEAKVGQFAGYVSEHSAYHHGEQSLASTIIGMAQQYVGSNNINILK 1073
            QRKILFC+FKRNF+ EAKV QF+GYVSEHSAYHHGEQSLASTIIGMAQ YVGSNNIN+L 
Sbjct: 726  QRKILFCSFKRNFIKEAKVAQFSGYVSEHSAYHHGEQSLASTIIGMAQDYVGSNNINLLM 785

Query: 1072 PNGQFGTRNQGGKDHASARYIFTQLSAITRFLFPKDDDILLDYQNEDGQTIEPTWYVPII 893
            PNGQFGTRN GGKDHAS RY++T+LS  TRFLFPKDDD LL Y NEDGQ+IEPTWY+PI+
Sbjct: 786  PNGQFGTRNMGGKDHASPRYVYTKLSPTTRFLFPKDDDNLLSYLNEDGQSIEPTWYMPIL 845

Query: 892  PVVLVNGSEGIGTGWSSFVPNYNPRDIIANVRHMLRDEPMEPMDPWYKGFRGTIEKTATK 713
            P+VLVNGSEGIGTGWSS++PNYNPRDIIAN+R +L  E MEPMDPWY+GFRGTIEKTATK
Sbjct: 846  PMVLVNGSEGIGTGWSSYIPNYNPRDIIANLRRLLNGEMMEPMDPWYRGFRGTIEKTATK 905

Query: 712  EAGATYTVTGIIEEVSDTTLRVTELPVRKWTQDYKDFLESLY---------PFIEDVREY 560
            EAG TYTV GIIEEV DTTLR+TELP+R+WTQDY++FLESL          PF+++ R+Y
Sbjct: 906  EAGVTYTVCGIIEEVDDTTLRITELPIRRWTQDYREFLESLSTGEKDKAKDPFVKEFRQY 965

Query: 559  HTTDSVNFEIDLSEENMRIAKQEGLLKKFKLTTTISTSNMHLFDSKGVIKKYDTPEKILE 380
                +V+FE+ L+EENM IAKQEGLLKKFKLT++ISTSNMHLFD  GVIKKYD+PE+ILE
Sbjct: 966  SDDVTVHFEVMLTEENMMIAKQEGLLKKFKLTSSISTSNMHLFDPNGVIKKYDSPEQILE 1025

Query: 379  DFFSIRFEFYEKRKKALMDNLERELLILENKVRFIMDVVEGKIVVSNRRRADLVLELKEK 200
            +FF +R E YEKRKK L++NLE +L++L+NKVRFI+ VV G+I+VSNR+RADL  EL+ K
Sbjct: 1026 EFFHLRLECYEKRKKILLENLELKLVMLDNKVRFILGVVHGEIIVSNRKRADLFQELQAK 1085

Query: 199  GFTPFPKKAKTTEISVAGSTDVPEETEENSDMATSQGVRASDYEYLLSMSIGSLTIEKVQ 20
            GFTPF K+ KT E +VAGSTD  EETEENS+  T++GV+ASDYEYLLSM+IG+LT+EKVQ
Sbjct: 1086 GFTPFRKETKTIETAVAGSTDDAEETEENSE-PTTKGVKASDYEYLLSMAIGALTLEKVQ 1144

Query: 19   ELCNNR 2
            ELC ++
Sbjct: 1145 ELCADK 1150


>ref|XP_010023597.1| PREDICTED: DNA topoisomerase 2-like [Eucalyptus grandis]
            gi|629093914|gb|KCW59909.1| hypothetical protein
            EUGRSUZ_H02633 [Eucalyptus grandis]
          Length = 1438

 Score = 1746 bits (4522), Expect = 0.0
 Identities = 864/1139 (75%), Positives = 980/1139 (86%), Gaps = 23/1139 (2%)
 Frame = -1

Query: 3349 PLTSSNNANIP---PEXXXXXXXXXAKTIEQTYQKKTQLEHILLRPDTYIGSIEKHNQTL 3179
            PL +SN AN     P           KT+E+TYQKK+QLEHILLRPDTYIGS+EKH Q+L
Sbjct: 6    PLQTSNIANTAAAAPPAPAAAAPRKGKTVEETYQKKSQLEHILLRPDTYIGSVEKHTQSL 65

Query: 3178 WVYE-EKQMVQKPITYVPGLYKIFDEILVNAADNKQRDPKMNSLKVTIDAEANCISVYNN 3002
            WVYE + +MV +P+TYVPGLYKIFDEILVNAADNKQRDP+M+SLKVTIDA+ N ISVYNN
Sbjct: 66   WVYEGDGEMVHRPVTYVPGLYKIFDEILVNAADNKQRDPRMDSLKVTIDADRNLISVYNN 125

Query: 3001 GDGVPVEIHQEEGVYVPELIFGHLLTSSNYDDHEKKTTGGRNGYGAKLTNIFSTEFVIET 2822
            GDGVPVE+H+EE VYVPELIFGHLLTSSNY+D+EKKTTGGRNGYGAKLTNIFSTEFVIET
Sbjct: 126  GDGVPVEMHREEKVYVPELIFGHLLTSSNYNDNEKKTTGGRNGYGAKLTNIFSTEFVIET 185

Query: 2821 ADGRRQRKYKQVFTCNMGNKSQPVISKCKESENWTKVTFKPDLSKFNMTHLEDDVVALMK 2642
            ADG+   KYKQVF+ NMG K  P I  CK  ENWTKV+FKPDL+KFNMTHLEDDVVALMK
Sbjct: 186  ADGKNGLKYKQVFSKNMGVKGAPEIKACKAGENWTKVSFKPDLAKFNMTHLEDDVVALMK 245

Query: 2641 KRVIDMAGCLGKNVKVELNGEDIRVRSFGDYCNLYLKSAF---------RIEEKV-DRWE 2492
            KRVIDMAGCLGK VKVELNG+ + V++F +Y  LYLKSA          RIEE V +RWE
Sbjct: 246  KRVIDMAGCLGKTVKVELNGKRVPVKTFAEYVGLYLKSASKNRPEASLPRIEETVNERWE 305

Query: 2491 VCVSLSDGQFQQVSFVNSISTIKGGTHVDYVTNQIATHLAEYVNKKRKNANLKPHSVRNH 2312
            VCVSLS+GQFQQVSFVN I+TIKGGTHVDYVTNQIA H+   VNKK KNANLK H V++H
Sbjct: 306  VCVSLSEGQFQQVSFVNGIATIKGGTHVDYVTNQIANHVMSVVNKKNKNANLKAHHVKSH 365

Query: 2311 LWVFVNCLIDNPAFDSQTKETLTLRQKSFGSECKLSDKFLSKVANSEIVNNILEWAEFKE 2132
            LWVFVN LIDNPAFDSQTKETLTLRQ SFGS+C+LSDKFL KVA S IV ++L WA FK+
Sbjct: 366  LWVFVNALIDNPAFDSQTKETLTLRQSSFGSKCELSDKFLQKVAKSGIVESLLSWANFKQ 425

Query: 2131 KKDLKKTDGTKSKRITGLTKLADANNAGGRNSEKCTLILTEGDSAATLAIAGLSVVGRDH 1952
             KDLKKTDG+K + + G+ KL DAN+AGGRNS+KCTLILTEGDSA  LA+AGLSVVGRD 
Sbjct: 426  SKDLKKTDGSKRENLRGIPKLEDANDAGGRNSDKCTLILTEGDSAKALAMAGLSVVGRDR 485

Query: 1951 YGVFPLRGKLLNVRDASTKQINDNAEIQNIKKILGLQHGKQYDSIKSLRYGHLMIMTDQD 1772
            YGVFPLRGKLLNVR+AS  QI +N EIQ +K+ILGLQ  K YDS+KSLRYGHLMIMTDQD
Sbjct: 486  YGVFPLRGKLLNVREASHSQIMENKEIQYMKQILGLQQNKDYDSVKSLRYGHLMIMTDQD 545

Query: 1771 HDGSHIKGLLINFIHSFWPSLLRIPSFLVEFITPIVKATHKNGEKRSFYTMPEYESWKES 1592
            HDGSHIKGLLINFIHSFWPSLL++PSFLVEFITPIVKATHKNG + SFYTMPEYESWKES
Sbjct: 546  HDGSHIKGLLINFIHSFWPSLLKVPSFLVEFITPIVKATHKNGRELSFYTMPEYESWKES 605

Query: 1591 LGDKARSWSIKYYKGLGTSTDKEGKEYFKDLGKHKKDFVWADDHDGEAIELAFSKKKIEA 1412
            LG  A  WSIKYYKGLGTST KEGK+YF++L  HKKDFVW DD DG+AIELAFSKKKIEA
Sbjct: 606  LGGNASGWSIKYYKGLGTSTSKEGKQYFQNLQLHKKDFVWVDDQDGDAIELAFSKKKIEA 665

Query: 1411 RKNWLRQFEPGTYLDQEDKLIKYRDFVNKELILFSIADLQRSIPSMVDGLKPGQRKILFC 1232
            RK WLRQ+EPGTYLDQ++KLIKY DFVNKELILFS+ADLQRSIPSMVDGLKPGQRKILFC
Sbjct: 666  RKTWLRQYEPGTYLDQKEKLIKYSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKILFC 725

Query: 1231 AFKRNFVHEAKVGQFAGYVSEHSAYHHGEQSLASTIIGMAQQYVGSNNINILKPNGQFGT 1052
            +FKRNF+ EAKV QF+GYVSEHSAYHHGEQSLASTIIGMAQ +VGSNNIN+L PNGQFGT
Sbjct: 726  SFKRNFIKEAKVAQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLMPNGQFGT 785

Query: 1051 RNQGGKDHASARYIFTQLSAITRFLFPKDDDILLDYQNEDGQTIEPTWYVPIIPVVLVNG 872
            RN GGKDHAS+RYI+T+LS ITRFLFPKDDD LL+Y NEDGQ+IEPTWY+PI+P VLVNG
Sbjct: 786  RNLGGKDHASSRYIYTKLSPITRFLFPKDDDNLLNYLNEDGQSIEPTWYMPILPTVLVNG 845

Query: 871  SEGIGTGWSSFVPNYNPRDIIANVRHMLRDEPMEPMDPWYKGFRGTIEKTATKEAGATYT 692
            SEGIGTGWSS++PNYNPRDIIAN+R +L  E MEPMDPWY+GFRGTIEKTATKEAG +YT
Sbjct: 846  SEGIGTGWSSYIPNYNPRDIIANLRRLLNGEMMEPMDPWYRGFRGTIEKTATKEAGVSYT 905

Query: 691  VTGIIEEVSDTTLRVTELPVRKWTQDYKDFLESLY---------PFIEDVREYHTTDSVN 539
            V GI+EEV DTTLR+TELP+R+WTQDY++FLESL          PF+++ R+Y    +V+
Sbjct: 906  VCGIVEEVDDTTLRITELPIRRWTQDYREFLESLSTGERDKTKDPFVKEFRQYSDDVTVH 965

Query: 538  FEIDLSEENMRIAKQEGLLKKFKLTTTISTSNMHLFDSKGVIKKYDTPEKILEDFFSIRF 359
            FE+ L+EENM IAKQEGLLKKFKLT+TISTSNMHLFDS GVIKKYD+PE+ILE+FF +R 
Sbjct: 966  FEVMLTEENMMIAKQEGLLKKFKLTSTISTSNMHLFDSNGVIKKYDSPEQILEEFFHLRL 1025

Query: 358  EFYEKRKKALMDNLERELLILENKVRFIMDVVEGKIVVSNRRRADLVLELKEKGFTPFPK 179
            E YEKRKK L++NLE +L++L+NKVRFI+ VV G+I+VSNR+RADL  EL+ KGF PF K
Sbjct: 1026 ECYEKRKKILLENLELKLVMLDNKVRFILGVVHGEIIVSNRKRADLFQELQAKGFAPFRK 1085

Query: 178  KAKTTEISVAGSTDVPEETEENSDMATSQGVRASDYEYLLSMSIGSLTIEKVQELCNNR 2
            + KT E  VAGSTD  EE EENS    ++GVRASDYEYLLSM+IG+LT+EKVQELC ++
Sbjct: 1086 ETKTIETGVAGSTDDSEEIEENS--GATKGVRASDYEYLLSMAIGTLTLEKVQELCADK 1142


>ref|XP_009800897.1| PREDICTED: LOW QUALITY PROTEIN: DNA topoisomerase 2-like [Nicotiana
            sylvestris]
          Length = 1474

 Score = 1739 bits (4505), Expect = 0.0
 Identities = 852/1139 (74%), Positives = 986/1139 (86%), Gaps = 17/1139 (1%)
 Frame = -1

Query: 3367 MAPKKAPLTSSNNANIPPEXXXXXXXXXAKTIEQTYQKKTQLEHILLRPDTYIGSIEKHN 3188
            MA KK PL SS+NANI             KTIEQTYQKKTQLEHILLRPDTYIGS+EKH 
Sbjct: 1    MASKKLPLQSSSNANIATNG---------KTIEQTYQKKTQLEHILLRPDTYIGSVEKHT 51

Query: 3187 QTLWVYEEKQMVQKPITYVPGLYKIFDEILVNAADNKQRDPKMNSLKVTIDAEANCISVY 3008
            QTLWV+E  +M  +P+TYVPGLYKIFDEILVNAADNKQRDPKM++++V ID E N ISVY
Sbjct: 52   QTLWVWENDKMTHRPVTYVPGLYKIFDEILVNAADNKQRDPKMDAVEVVIDPEQNFISVY 111

Query: 3007 NNGDGVPVEIHQEEGVYVPELIFGHLLTSSNYDDHEKKTTGGRNGYGAKLTNIFSTEFVI 2828
            NNGDG+PVEIHQEEGVYVPELIFGHLLTSSNYDD EKKTTGGRNGYGAKLTNIFSTEFVI
Sbjct: 112  NNGDGIPVEIHQEEGVYVPELIFGHLLTSSNYDDAEKKTTGGRNGYGAKLTNIFSTEFVI 171

Query: 2827 ETADGRRQRKYKQVFTCNMGNKSQPVISKCKESENWTKVTFKPDLSKFNMTHLEDDVVAL 2648
            ETADG+RQ+KYKQVF+ NMG K +P+I+KCK SENWTKV+FKPDL+KFNM HLE+DVVAL
Sbjct: 172  ETADGKRQKKYKQVFSSNMGKKGEPIITKCKASENWTKVSFKPDLAKFNMEHLEEDVVAL 231

Query: 2647 MKKRVIDMAGCLGKNVKVELNGEDIRVRSFGDYCNLYLKSAFRIEEKVD--------RWE 2492
            M+KRVID+ GCLGK VKV+LN + I V+SF +YC L+L S     E +         RWE
Sbjct: 232  MRKRVIDLGGCLGKTVKVKLNEQRIPVKSFEEYCKLFLDSTDAKREFLKVTDADGLLRWE 291

Query: 2491 VCVSLSDGQFQQVSFVNSISTIKGGTHVDYVTNQIATHLAEYVNKKRKNANLKPHSVRNH 2312
            +CVSLS+GQFQQVSFVNSI+TIKGGTHVDYV NQIA H+   VNKK KNAN+K H+V+NH
Sbjct: 292  ICVSLSEGQFQQVSFVNSIATIKGGTHVDYVANQIANHIMGVVNKKNKNANIKAHAVKNH 351

Query: 2311 LWVFVNCLIDNPAFDSQTKETLTLRQKSFGSECKLSDKFLSKVA-NSEIVNNILEWAEFK 2135
            LW+FVN LIDNPAFDSQTKETLTLRQ SFGS+C+L   FL KV  N  IV  +L WA+FK
Sbjct: 352  LWMFVNALIDNPAFDSQTKETLTLRQSSFGSKCELQPDFLKKVEKNIGIVETLLSWADFK 411

Query: 2134 EKKDLKKTDGTKSKRITGLTKLADANNAGGRNSEKCTLILTEGDSAATLAIAGLSVVGRD 1955
              KDLKKTDG KS+++  + KL DAN+AGGRNSEKCTLILTEGDSA  LA+AG+SVVGRD
Sbjct: 412  NSKDLKKTDGKKSEKVK-VEKLEDANDAGGRNSEKCTLILTEGDSAKALAMAGISVVGRD 470

Query: 1954 HYGVFPLRGKLLNVRDASTKQINDNAEIQNIKKILGLQHGKQYDSIKSLRYGHLMIMTDQ 1775
            HYGVFPLRGKLLNVR+AS KQ+++N EI+ IKKILGLQ GK+YDS+KSLRYGHLMIMTDQ
Sbjct: 471  HYGVFPLRGKLLNVREASHKQVSENKEIEAIKKILGLQTGKEYDSVKSLRYGHLMIMTDQ 530

Query: 1774 DHDGSHIKGLLINFIHSFWPSLLRIPSFLVEFITPIVKATHKNGEKRSFYTMPEYESWKE 1595
            DHDGSHIKGLLINFIH+FWPSLL++PSFL+EFITPIVKATHK+G+  SFYTMPEYESW++
Sbjct: 531  DHDGSHIKGLLINFIHTFWPSLLKVPSFLIEFITPIVKATHKSGKILSFYTMPEYESWRK 590

Query: 1594 SLGDKARSWSIKYYKGLGTSTDKEGKEYFKDLGKHKKDFVWADDHDGEAIELAFSKKKIE 1415
            SLG  +  WSIKYYKGLGTST KEGKEYF+DL KH+KDF+WAD+ DGE+IELAFSKKKIE
Sbjct: 591  SLGANSSGWSIKYYKGLGTSTSKEGKEYFQDLQKHRKDFIWADNQDGESIELAFSKKKIE 650

Query: 1414 ARKNWLRQFEPGTYLDQEDKLIKYRDFVNKELILFSIADLQRSIPSMVDGLKPGQRKILF 1235
            ARKNWLRQFEPGT+LDQ++K I Y +FVNKELILFS+ADLQRSIPSM+DGLKPGQRKILF
Sbjct: 651  ARKNWLRQFEPGTHLDQKEKYISYTEFVNKELILFSMADLQRSIPSMLDGLKPGQRKILF 710

Query: 1234 CAFKRNFVHEAKVGQFAGYVSEHSAYHHGEQSLASTIIGMAQQYVGSNNINILKPNGQFG 1055
            CAFKRNFV EAKV QF+GYVSEHSAYHHGEQSL+STIIGMAQ YVGSNN+N+L+PNGQFG
Sbjct: 711  CAFKRNFVKEAKVSQFSGYVSEHSAYHHGEQSLSSTIIGMAQDYVGSNNVNLLQPNGQFG 770

Query: 1054 TRNQGGKDHASARYIFTQLSAITRFLFPKDDDILLDYQNEDGQTIEPTWYVPIIPVVLVN 875
            TRN GGKDHAS+RYI+T+LS I RFLFPK+DD +LDY NEDGQ+IEPTWYVPI+P+VL+N
Sbjct: 771  TRNMGGKDHASSRYIYTRLSPIARFLFPKEDDTILDYLNEDGQSIEPTWYVPIVPMVLIN 830

Query: 874  GSEGIGTGWSSFVPNYNPRDIIANVRHMLRDEPMEPMDPWYKGFRGTIEKTATKEAGATY 695
            GSEGIGTGWSS+VPNYNPRD++ANVR +L DEPMEPMDPWYKGF+GTIEKTATKEAGATY
Sbjct: 831  GSEGIGTGWSSYVPNYNPRDLVANVRRLLNDEPMEPMDPWYKGFKGTIEKTATKEAGATY 890

Query: 694  TVTGIIEEVSDTTLRVTELPVRKWTQDYKDFLESLY--------PFIEDVREYHTTDSVN 539
            TVTGIIEE+++TTLR++ELPVR+WT+DYK FLES+         PFI++VR Y   +SV 
Sbjct: 891  TVTGIIEELNETTLRISELPVRRWTEDYKQFLESMTVSNDKAKDPFIKEVRAYGDENSVC 950

Query: 538  FEIDLSEENMRIAKQEGLLKKFKLTTTISTSNMHLFDSKGVIKKYDTPEKILEDFFSIRF 359
            FE+ LSEEN+ +A+QEGLLKKFKL TTISTSNMHLFDSKG IKKYD PE ILE+F+ +R 
Sbjct: 951  FEVILSEENLILAQQEGLLKKFKLATTISTSNMHLFDSKGKIKKYDNPEDILEEFYHVRL 1010

Query: 358  EFYEKRKKALMDNLERELLILENKVRFIMDVVEGKIVVSNRRRADLVLELKEKGFTPFPK 179
            E+YEKRK+AL++ LE ELL +ENKV+FI+ VV+G+I+V+NR+RADL+LELKEKGFTPFPK
Sbjct: 1011 EYYEKRKRALLEILELELLRIENKVKFILGVVKGEIIVNNRKRADLLLELKEKGFTPFPK 1070

Query: 178  KAKTTEISVAGSTDVPEETEENSDMATSQGVRASDYEYLLSMSIGSLTIEKVQELCNNR 2
            K K  E  VA ++D  E++EE      ++GVRA DY+YLLSM+IG+LT+EKVQELC  R
Sbjct: 1071 K-KAVEAVVADTSDDAEDSEEE----LNRGVRAGDYDYLLSMAIGTLTLEKVQELCAER 1124


>emb|CBI24922.3| unnamed protein product [Vitis vinifera]
          Length = 1452

 Score = 1737 bits (4498), Expect = 0.0
 Identities = 861/1136 (75%), Positives = 971/1136 (85%), Gaps = 18/1136 (1%)
 Frame = -1

Query: 3355 KAPLTSSNNANIPPEXXXXXXXXXAKTIEQTYQKKTQLEHILLRPDTYIGSIEKHNQTLW 3176
            K PL SSNNAN+P +          KTIE+TYQKK+QLEHILLRPDTYIGSIEKH Q LW
Sbjct: 6    KLPLQSSNNANMPAKPAG-------KTIEETYQKKSQLEHILLRPDTYIGSIEKHTQALW 58

Query: 3175 VYEEKQMVQKPITYVPGLYKIFDEILVNAADNKQRDPKMNSLKVTIDAEANCISVYNNGD 2996
            V+E  +MV + ++YVPGLYKIFDEILVNAADNKQRDP M+S+KV ID E NCISVYNNGD
Sbjct: 59   VFENNEMVHRSVSYVPGLYKIFDEILVNAADNKQRDPSMDSVKVVIDVEKNCISVYNNGD 118

Query: 2995 GVPVEIHQEEGVYVPELIFGHLLTSSNYDDHEKKTTGGRNGYGAKLTNIFSTEFVIETAD 2816
            GVPVEIHQEEGVYVPE+IFGHLLTSSNYDD  KKTTGGRNGYGAKLTNIFSTEFVIETAD
Sbjct: 119  GVPVEIHQEEGVYVPEMIFGHLLTSSNYDDDVKKTTGGRNGYGAKLTNIFSTEFVIETAD 178

Query: 2815 GRRQRKYKQVFTCNMGNKSQPVISKCKESENWTKVTFKPDLSKFNMTHLEDDVVALMKKR 2636
            GRRQ+KYKQVF+ NMG KS+PVI+KCKE ENWTKV+FKPDL+KFNMTHLEDDVVALMKKR
Sbjct: 179  GRRQKKYKQVFSNNMGKKSEPVITKCKERENWTKVSFKPDLAKFNMTHLEDDVVALMKKR 238

Query: 2635 VIDMAGCLGKNVKVELNGEDIRVRSFGDYCNLYLKSAF--------RIEEKV-DRWEVCV 2483
            V+D+AGCLGK VKVELNG+ I V+SF DY NLYL+SA         RI EKV +RWE+CV
Sbjct: 239  VVDIAGCLGKTVKVELNGQRIPVKSFNDYVNLYLQSAAKSRPESLPRIAEKVNERWEICV 298

Query: 2482 SLSDGQFQQVSFVNSISTIKGGTHVDYVTNQIATHLAEYVNKKRKNANLKPHSVRNHLWV 2303
            SLS+GQFQQVSFVNSI+TIKGGTHVDYVTNQIA  +   VNKK KNAN+K H+V+NHLWV
Sbjct: 299  SLSEGQFQQVSFVNSIATIKGGTHVDYVTNQIANFVMSIVNKKNKNANIKAHTVKNHLWV 358

Query: 2302 FVNCLIDNPAFDSQTKETLTLRQKSFGSECKLSDKFLSKVANSEIVNNILEWAEFKEKKD 2123
            FVN LIDNPAFDSQTKETLT+RQ SFGS+C+LS +FL KV+ S +V ++L WA++K+ KD
Sbjct: 359  FVNALIDNPAFDSQTKETLTIRQSSFGSKCELSQEFLKKVSKSGVVESLLSWADYKQNKD 418

Query: 2122 LKKTDGTKSKRITGLTKLADANNAGGRNSEKCTLILTEGDSAATLAIAGLSVVGRDHYGV 1943
            LKKTDGTK +R+TG+TKL DAN+AGGRNSEKCTLILTEGDSA  LA+AG+SVVGR+HYGV
Sbjct: 419  LKKTDGTKRQRLTGITKLEDANDAGGRNSEKCTLILTEGDSAKALAMAGISVVGRNHYGV 478

Query: 1942 FPLRGKLLNVRDASTKQINDNAEIQNIKKILGLQHGKQYDSIKSLRYGHLMIMTDQDHDG 1763
            FPLRGKLLNVRDA  KQI +NAEIQNIK+ILGLQ GK+YDSIKSLRYGHLMIMTDQDHDG
Sbjct: 479  FPLRGKLLNVRDAQKKQILENAEIQNIKQILGLQQGKEYDSIKSLRYGHLMIMTDQDHDG 538

Query: 1762 SHIKGLLINFIHSFWPSLLRIPSFLVEFITPIVKATHKNGEKRSFYTMPEYESWKESLGD 1583
            SHIKGLLINFIHSFWPSLL+IPSFLVEFITPIVKATH+NG   SFY+MPEYESWKESLG 
Sbjct: 539  SHIKGLLINFIHSFWPSLLKIPSFLVEFITPIVKATHRNGRVLSFYSMPEYESWKESLGG 598

Query: 1582 KARSWSIKYYKGLGTSTDKEGKEYFKDLGKHKKDFVWADDHDGEAIELAFSKKKIEARKN 1403
             A  WSIKYYKGLGTST KEGKEYFKDLGKHKKDF+W D+ DG+AIELAFSKKKIE RKN
Sbjct: 599  NASGWSIKYYKGLGTSTSKEGKEYFKDLGKHKKDFMWVDEKDGDAIELAFSKKKIEERKN 658

Query: 1402 WLRQFEPGTYLDQEDKLIKYRDFVNKELILFSIADLQRSIPSMVDGLKPGQRKILFCAFK 1223
            WLRQF+PGTYLDQ++KLIKY DFVNKELILFS+ADLQRSIPSMVDGLKPGQRKILFC+FK
Sbjct: 659  WLRQFQPGTYLDQKEKLIKYSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKILFCSFK 718

Query: 1222 RNFVHEAKVGQFAGYVSEHSAYHHGEQSLASTIIGMAQQYVGSNNINILKPNGQFGTRNQ 1043
            RNF+ EAK+ QF+GYVSEHSAYHHGEQSLASTIIGMAQ +VGSNNIN+L PNGQFGTR+Q
Sbjct: 719  RNFIKEAKIAQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRHQ 778

Query: 1042 GGKDHASARYIFTQLSAITRFLFPKDDDILLDYQNEDGQTIEPTWYVPIIPVVLVNGSEG 863
            GGKDHASARYI+T+LS ITRFLFPKDDDILLDY NEDGQ+IEPTWYVP IP+VLVNGSEG
Sbjct: 779  GGKDHASARYIYTRLSPITRFLFPKDDDILLDYLNEDGQSIEPTWYVPTIPMVLVNGSEG 838

Query: 862  IGTGWSSFVPNYNPRDIIANVRHMLRDEPMEPMDPWYKGFRGTIEKT-ATKEAGATYTVT 686
            IGTGWSS +PNYNPRDIIANVR +L  E MEPMDPWY+GFRGTIEKT  TK+    YTV 
Sbjct: 839  IGTGWSSSIPNYNPRDIIANVRRLLNGEMMEPMDPWYRGFRGTIEKTDPTKQESVGYTVK 898

Query: 685  GIIEEVSDTTLRVTELPVRKWTQDYKDFLESLY--------PFIEDVREYHTTDSVNFEI 530
            GIIEEV++TTLR++ELPVRKWTQDYK+FLES+         PFI+D +E++   +V+FE+
Sbjct: 899  GIIEEVNETTLRISELPVRKWTQDYKEFLESIMTGNDKIKDPFIKDYKEHNDDTTVHFEV 958

Query: 529  DLSEENMRIAKQEGLLKKFKLTTTISTSNMHLFDSKGVIKKYDTPEKILEDFFSIRFEFY 350
             +SEEN+ +AKQEGLL+KFKLTT ISTSNMHLFDS G IKKY+TPE+ILE+FF +R EFY
Sbjct: 959  IMSEENLLMAKQEGLLQKFKLTTKISTSNMHLFDSNGTIKKYETPEQILEEFFHLRLEFY 1018

Query: 349  EKRKKALMDNLERELLILENKVRFIMDVVEGKIVVSNRRRADLVLELKEKGFTPFPKKAK 170
            EKRK+ L+DNLE ELL LENKVRFI+ VV G+I+VSNR+RADL  EL +K          
Sbjct: 1019 EKRKRVLLDNLELELLKLENKVRFILGVVRGEIIVSNRKRADLFHELHQK---------- 1068

Query: 169  TTEISVAGSTDVPEETEENSDMATSQGVRASDYEYLLSMSIGSLTIEKVQELCNNR 2
                                       VRA+DYEYLLSM+IG+LT+EKVQELC +R
Sbjct: 1069 ---------------------------VRATDYEYLLSMAIGTLTLEKVQELCADR 1097


>ref|XP_008231458.1| PREDICTED: DNA topoisomerase 2 isoform X2 [Prunus mume]
          Length = 1470

 Score = 1736 bits (4497), Expect = 0.0
 Identities = 855/1136 (75%), Positives = 975/1136 (85%), Gaps = 17/1136 (1%)
 Frame = -1

Query: 3358 KKAPLTSSNNANIPPEXXXXXXXXXAKTIEQTYQKKTQLEHILLRPDTYIGSIEKHNQTL 3179
            KK PL +SN+ANI P           KTIE+ YQKK+QLEHILLRPDTYIGSIEKH Q L
Sbjct: 5    KKRPLQTSNSANIAPAPTDGQG----KTIEEMYQKKSQLEHILLRPDTYIGSIEKHTQIL 60

Query: 3178 WVYEEKQMVQKPITYVPGLYKIFDEILVNAADNKQRDPKMNSLKVTIDAEANCISVYNNG 2999
            WVY+  +MV + I+YVPGLYKIFDEILVNAADNKQRD  M+++KVTID E NCISVYNNG
Sbjct: 61   WVYQNDEMVNRSISYVPGLYKIFDEILVNAADNKQRDSSMDAVKVTIDVEQNCISVYNNG 120

Query: 2998 DGVPVEIHQEEGVYVPELIFGHLLTSSNYDDHEKKTTGGRNGYGAKLTNIFSTEFVIETA 2819
             GVPVEIHQEE VYVPELIFGHLLTSSNYDD EKKTTGGRNGYGAKLTNIFSTEF+IETA
Sbjct: 121  AGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFIIETA 180

Query: 2818 DGRRQRKYKQVFTCNMGNKSQPVISKCKESENWTKVTFKPDLSKFNMTHLEDDVVALMKK 2639
            DG+RQ+KYKQVFT NMG K++PVI+KCKESENWT+VT+KPDLSKFNMTHLEDDVVALMKK
Sbjct: 181  DGKRQKKYKQVFTNNMGKKTEPVITKCKESENWTRVTYKPDLSKFNMTHLEDDVVALMKK 240

Query: 2638 RVIDMAGCLGKNVKVELNGEDIRVRSFGDYCNLYLKSAF--------RIEEKV-DRWEVC 2486
            RVID+AGCLGK VKVELNG+ + V+SF DY +LYL+SA         R+ EKV DRWE+C
Sbjct: 241  RVIDLAGCLGKTVKVELNGKRVPVKSFLDYVDLYLQSACKSRDTPLPRMTEKVNDRWEIC 300

Query: 2485 VSLSDGQFQQVSFVNSISTIKGGTHVDYVTNQIATHLAEYVNKKRKNANLKPHSVRNHLW 2306
            VSLSDGQFQQVSFVN I+TIKGGTHVDYVTNQI  H+   VNKK KNANLK H+V+N+LW
Sbjct: 301  VSLSDGQFQQVSFVNGIATIKGGTHVDYVTNQITNHVMNIVNKKNKNANLKAHNVKNYLW 360

Query: 2305 VFVNCLIDNPAFDSQTKETLTLRQKSFGSECKLSDKFLSKVANSEIVNNILEWAEFKEKK 2126
            VFVN LIDNPAFDSQTKETLT+R  SFGS+C+L+  FL+KVA S IV+++L WA FK+ K
Sbjct: 361  VFVNALIDNPAFDSQTKETLTIRPNSFGSKCELTPAFLTKVAKSGIVDSLLSWANFKQNK 420

Query: 2125 DLKKTDGTKSKRITGLTKLADANNAGGRNSEKCTLILTEGDSAATLAIAGLSVVGRDHYG 1946
            DLKKTDGTK++R+  + KL DAN AGG+NSEKCTLILTEGDSA  LA+AGL+VVGRDHYG
Sbjct: 421  DLKKTDGTKTERVHNINKLEDANLAGGKNSEKCTLILTEGDSAKALAMAGLAVVGRDHYG 480

Query: 1945 VFPLRGKLLNVRDASTKQINDNAEIQNIKKILGLQHGKQYDSIKSLRYGHLMIMTDQDHD 1766
            VFPLRGKLLNVR+AS  Q+ DN EI+NIK+ILGLQ  K+Y S+KSLRYG LMIMTDQDHD
Sbjct: 481  VFPLRGKLLNVREASATQVRDNEEIKNIKRILGLQQDKEYTSLKSLRYGSLMIMTDQDHD 540

Query: 1765 GSHIKGLLINFIHSFWPSLLRIPSFLVEFITPIVKATHKNGEKRSFYTMPEYESWKESLG 1586
            GSHIKGLLINFIHSFWPSLL+IPSFLVEFITPIVKATHKNG+  +FY+MPEYE+WKESL 
Sbjct: 541  GSHIKGLLINFIHSFWPSLLKIPSFLVEFITPIVKATHKNGKSLAFYSMPEYEAWKESLR 600

Query: 1585 DKARSWSIKYYKGLGTSTDKEGKEYFKDLGKHKKDFVWADDHDGEAIELAFSKKKIEARK 1406
              A  WSIKYYKGLGTST KEG++YF++L  HKKDF+W D+ DGEAIELAFSKKKIE RK
Sbjct: 601  GNASGWSIKYYKGLGTSTSKEGRDYFQNLAMHKKDFIWIDERDGEAIELAFSKKKIEERK 660

Query: 1405 NWLRQFEPGTYLDQEDKLIKYRDFVNKELILFSIADLQRSIPSMVDGLKPGQRKILFCAF 1226
            NWLRQFEP  +LDQ++KLIKY DFV+KELI FS+ADLQRSIPSMVDGLKPGQRKILFC+F
Sbjct: 661  NWLRQFEPSVHLDQKEKLIKYSDFVHKELIQFSMADLQRSIPSMVDGLKPGQRKILFCSF 720

Query: 1225 KRNFVHEAKVGQFAGYVSEHSAYHHGEQSLASTIIGMAQQYVGSNNINILKPNGQFGTRN 1046
            KRNFV EAKV QF+GYVSEHSAYHHGEQSLASTIIGMAQ YVGSNNIN+L+PNGQFGTRN
Sbjct: 721  KRNFVKEAKVAQFSGYVSEHSAYHHGEQSLASTIIGMAQDYVGSNNINLLQPNGQFGTRN 780

Query: 1045 QGGKDHASARYIFTQLSAITRFLFPKDDDILLDYQNEDGQTIEPTWYVPIIPVVLVNGSE 866
             GGKDHASARYI+T+LS ITRFLFPKDDD LLDY NEDGQ+IEPTWYVPIIP VLVNGSE
Sbjct: 781  LGGKDHASARYIYTRLSPITRFLFPKDDDRLLDYLNEDGQSIEPTWYVPIIPTVLVNGSE 840

Query: 865  GIGTGWSSFVPNYNPRDIIANVRHMLRDEPMEPMDPWYKGFRGTIEKTATKEAGATYTVT 686
            GIGTGWSS++PNYNPRDI+ANVR +L  E M PMDPWY+GF GTIEKT  KE+G +YTV 
Sbjct: 841  GIGTGWSSYIPNYNPRDIVANVRRLLNGEAMVPMDPWYRGFAGTIEKT-VKESGVSYTVC 899

Query: 685  GIIEEVSDTTLRVTELPVRKWTQDYKDFLESLY--------PFIEDVREYHTTDSVNFEI 530
            G+IEE ++TT+R++ELP+R+WTQDYK+FLES+         PFIE   ++    +V+  +
Sbjct: 900  GVIEEGNETTVRISELPIRRWTQDYKEFLESISQGNDKAKDPFIEGFTQHSDHSTVDIIV 959

Query: 529  DLSEENMRIAKQEGLLKKFKLTTTISTSNMHLFDSKGVIKKYDTPEKILEDFFSIRFEFY 350
             L EEN+  A+QEGLLKKFKLTT+ISTSNMHLFD KGVIKKYDTPE+ILE+FF +R EFY
Sbjct: 960  HLPEENLMAARQEGLLKKFKLTTSISTSNMHLFDPKGVIKKYDTPEQILEEFFHLRLEFY 1019

Query: 349  EKRKKALMDNLERELLILENKVRFIMDVVEGKIVVSNRRRADLVLELKEKGFTPFPKKAK 170
            EKRKK L+DNLE ELL LENKVRFI+ VV G+I+VSNRRRADL LEL++KGFTPFPKK K
Sbjct: 1020 EKRKKVLLDNLEMELLKLENKVRFILAVVNGEIIVSNRRRADLFLELQQKGFTPFPKKTK 1079

Query: 169  TTEISVAGSTDVPEETEENSDMATSQGVRASDYEYLLSMSIGSLTIEKVQELCNNR 2
              E  VAG+ +  EETEENS+ A+  G R SDYEYL+SM+IG+LTIE+VQ LC +R
Sbjct: 1080 AQEPEVAGAIEDTEETEENSESASGNGARISDYEYLISMAIGTLTIERVQALCADR 1135


>ref|XP_008231457.1| PREDICTED: DNA topoisomerase 2 isoform X1 [Prunus mume]
          Length = 1471

 Score = 1736 bits (4497), Expect = 0.0
 Identities = 855/1136 (75%), Positives = 975/1136 (85%), Gaps = 17/1136 (1%)
 Frame = -1

Query: 3358 KKAPLTSSNNANIPPEXXXXXXXXXAKTIEQTYQKKTQLEHILLRPDTYIGSIEKHNQTL 3179
            KK PL +SN+ANI P           KTIE+ YQKK+QLEHILLRPDTYIGSIEKH Q L
Sbjct: 5    KKRPLQTSNSANIAPAPTDGQG----KTIEEMYQKKSQLEHILLRPDTYIGSIEKHTQIL 60

Query: 3178 WVYEEKQMVQKPITYVPGLYKIFDEILVNAADNKQRDPKMNSLKVTIDAEANCISVYNNG 2999
            WVY+  +MV + I+YVPGLYKIFDEILVNAADNKQRD  M+++KVTID E NCISVYNNG
Sbjct: 61   WVYQNDEMVNRSISYVPGLYKIFDEILVNAADNKQRDSSMDAVKVTIDVEQNCISVYNNG 120

Query: 2998 DGVPVEIHQEEGVYVPELIFGHLLTSSNYDDHEKKTTGGRNGYGAKLTNIFSTEFVIETA 2819
             GVPVEIHQEE VYVPELIFGHLLTSSNYDD EKKTTGGRNGYGAKLTNIFSTEF+IETA
Sbjct: 121  AGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFIIETA 180

Query: 2818 DGRRQRKYKQVFTCNMGNKSQPVISKCKESENWTKVTFKPDLSKFNMTHLEDDVVALMKK 2639
            DG+RQ+KYKQVFT NMG K++PVI+KCKESENWT+VT+KPDLSKFNMTHLEDDVVALMKK
Sbjct: 181  DGKRQKKYKQVFTNNMGKKTEPVITKCKESENWTRVTYKPDLSKFNMTHLEDDVVALMKK 240

Query: 2638 RVIDMAGCLGKNVKVELNGEDIRVRSFGDYCNLYLKSAF--------RIEEKV-DRWEVC 2486
            RVID+AGCLGK VKVELNG+ + V+SF DY +LYL+SA         R+ EKV DRWE+C
Sbjct: 241  RVIDLAGCLGKTVKVELNGKRVPVKSFLDYVDLYLQSACKSRDTPLPRMTEKVNDRWEIC 300

Query: 2485 VSLSDGQFQQVSFVNSISTIKGGTHVDYVTNQIATHLAEYVNKKRKNANLKPHSVRNHLW 2306
            VSLSDGQFQQVSFVN I+TIKGGTHVDYVTNQI  H+   VNKK KNANLK H+V+N+LW
Sbjct: 301  VSLSDGQFQQVSFVNGIATIKGGTHVDYVTNQITNHVMNIVNKKNKNANLKAHNVKNYLW 360

Query: 2305 VFVNCLIDNPAFDSQTKETLTLRQKSFGSECKLSDKFLSKVANSEIVNNILEWAEFKEKK 2126
            VFVN LIDNPAFDSQTKETLT+R  SFGS+C+L+  FL+KVA S IV+++L WA FK+ K
Sbjct: 361  VFVNALIDNPAFDSQTKETLTIRPNSFGSKCELTPAFLTKVAKSGIVDSLLSWANFKQNK 420

Query: 2125 DLKKTDGTKSKRITGLTKLADANNAGGRNSEKCTLILTEGDSAATLAIAGLSVVGRDHYG 1946
            DLKKTDGTK++R+  + KL DAN AGG+NSEKCTLILTEGDSA  LA+AGL+VVGRDHYG
Sbjct: 421  DLKKTDGTKTERVHNINKLEDANLAGGKNSEKCTLILTEGDSAKALAMAGLAVVGRDHYG 480

Query: 1945 VFPLRGKLLNVRDASTKQINDNAEIQNIKKILGLQHGKQYDSIKSLRYGHLMIMTDQDHD 1766
            VFPLRGKLLNVR+AS  Q+ DN EI+NIK+ILGLQ  K+Y S+KSLRYG LMIMTDQDHD
Sbjct: 481  VFPLRGKLLNVREASATQVRDNEEIKNIKRILGLQQDKEYTSLKSLRYGSLMIMTDQDHD 540

Query: 1765 GSHIKGLLINFIHSFWPSLLRIPSFLVEFITPIVKATHKNGEKRSFYTMPEYESWKESLG 1586
            GSHIKGLLINFIHSFWPSLL+IPSFLVEFITPIVKATHKNG+  +FY+MPEYE+WKESL 
Sbjct: 541  GSHIKGLLINFIHSFWPSLLKIPSFLVEFITPIVKATHKNGKSLAFYSMPEYEAWKESLR 600

Query: 1585 DKARSWSIKYYKGLGTSTDKEGKEYFKDLGKHKKDFVWADDHDGEAIELAFSKKKIEARK 1406
              A  WSIKYYKGLGTST KEG++YF++L  HKKDF+W D+ DGEAIELAFSKKKIE RK
Sbjct: 601  GNASGWSIKYYKGLGTSTSKEGRDYFQNLAMHKKDFIWIDERDGEAIELAFSKKKIEERK 660

Query: 1405 NWLRQFEPGTYLDQEDKLIKYRDFVNKELILFSIADLQRSIPSMVDGLKPGQRKILFCAF 1226
            NWLRQFEP  +LDQ++KLIKY DFV+KELI FS+ADLQRSIPSMVDGLKPGQRKILFC+F
Sbjct: 661  NWLRQFEPSVHLDQKEKLIKYSDFVHKELIQFSMADLQRSIPSMVDGLKPGQRKILFCSF 720

Query: 1225 KRNFVHEAKVGQFAGYVSEHSAYHHGEQSLASTIIGMAQQYVGSNNINILKPNGQFGTRN 1046
            KRNFV EAKV QF+GYVSEHSAYHHGEQSLASTIIGMAQ YVGSNNIN+L+PNGQFGTRN
Sbjct: 721  KRNFVKEAKVAQFSGYVSEHSAYHHGEQSLASTIIGMAQDYVGSNNINLLQPNGQFGTRN 780

Query: 1045 QGGKDHASARYIFTQLSAITRFLFPKDDDILLDYQNEDGQTIEPTWYVPIIPVVLVNGSE 866
             GGKDHASARYI+T+LS ITRFLFPKDDD LLDY NEDGQ+IEPTWYVPIIP VLVNGSE
Sbjct: 781  LGGKDHASARYIYTRLSPITRFLFPKDDDRLLDYLNEDGQSIEPTWYVPIIPTVLVNGSE 840

Query: 865  GIGTGWSSFVPNYNPRDIIANVRHMLRDEPMEPMDPWYKGFRGTIEKTATKEAGATYTVT 686
            GIGTGWSS++PNYNPRDI+ANVR +L  E M PMDPWY+GF GTIEKT  KE+G +YTV 
Sbjct: 841  GIGTGWSSYIPNYNPRDIVANVRRLLNGEAMVPMDPWYRGFAGTIEKT-VKESGVSYTVC 899

Query: 685  GIIEEVSDTTLRVTELPVRKWTQDYKDFLESLY--------PFIEDVREYHTTDSVNFEI 530
            G+IEE ++TT+R++ELP+R+WTQDYK+FLES+         PFIE   ++    +V+  +
Sbjct: 900  GVIEEGNETTVRISELPIRRWTQDYKEFLESISQGNDKAKDPFIEGFTQHSDHSTVDIIV 959

Query: 529  DLSEENMRIAKQEGLLKKFKLTTTISTSNMHLFDSKGVIKKYDTPEKILEDFFSIRFEFY 350
             L EEN+  A+QEGLLKKFKLTT+ISTSNMHLFD KGVIKKYDTPE+ILE+FF +R EFY
Sbjct: 960  HLPEENLMAARQEGLLKKFKLTTSISTSNMHLFDPKGVIKKYDTPEQILEEFFHLRLEFY 1019

Query: 349  EKRKKALMDNLERELLILENKVRFIMDVVEGKIVVSNRRRADLVLELKEKGFTPFPKKAK 170
            EKRKK L+DNLE ELL LENKVRFI+ VV G+I+VSNRRRADL LEL++KGFTPFPKK K
Sbjct: 1020 EKRKKVLLDNLEMELLKLENKVRFILAVVNGEIIVSNRRRADLFLELQQKGFTPFPKKTK 1079

Query: 169  TTEISVAGSTDVPEETEENSDMATSQGVRASDYEYLLSMSIGSLTIEKVQELCNNR 2
              E  VAG+ +  EETEENS+ A+  G R SDYEYL+SM+IG+LTIE+VQ LC +R
Sbjct: 1080 AQEPEVAGAIEDTEETEENSESASGNGARISDYEYLISMAIGTLTIERVQALCADR 1135


>ref|XP_009630917.1| PREDICTED: LOW QUALITY PROTEIN: DNA topoisomerase 2-like [Nicotiana
            tomentosiformis]
          Length = 1486

 Score = 1735 bits (4494), Expect = 0.0
 Identities = 850/1139 (74%), Positives = 985/1139 (86%), Gaps = 17/1139 (1%)
 Frame = -1

Query: 3367 MAPKKAPLTSSNNANIPPEXXXXXXXXXAKTIEQTYQKKTQLEHILLRPDTYIGSIEKHN 3188
            MA KK PL SS+NANI             KTIEQTYQKKTQLEHILLRPDTYIGS+EKH 
Sbjct: 1    MASKKLPLQSSSNANIVTNG---------KTIEQTYQKKTQLEHILLRPDTYIGSVEKHT 51

Query: 3187 QTLWVYEEKQMVQKPITYVPGLYKIFDEILVNAADNKQRDPKMNSLKVTIDAEANCISVY 3008
            QTLWV+E  +M+ +P+TYVPGLYKIFDEILVNAADNKQRDPKM++++V ID E N ISVY
Sbjct: 52   QTLWVWENDKMIHRPVTYVPGLYKIFDEILVNAADNKQRDPKMDAVEVVIDPEQNFISVY 111

Query: 3007 NNGDGVPVEIHQEEGVYVPELIFGHLLTSSNYDDHEKKTTGGRNGYGAKLTNIFSTEFVI 2828
            NNGDG+PVEIHQEEGVYVPELIFGHLLTSSNYDD EKKTTGGRNGYGAKLTNIFSTEFVI
Sbjct: 112  NNGDGIPVEIHQEEGVYVPELIFGHLLTSSNYDDAEKKTTGGRNGYGAKLTNIFSTEFVI 171

Query: 2827 ETADGRRQRKYKQVFTCNMGNKSQPVISKCKESENWTKVTFKPDLSKFNMTHLEDDVVAL 2648
            ETADG+RQ+KYKQVF+ NMG K +P+I+KCK SENWTKV+FKPDL+KFNM HLE+DVVAL
Sbjct: 172  ETADGKRQKKYKQVFSNNMGKKGEPIITKCKASENWTKVSFKPDLAKFNMEHLEEDVVAL 231

Query: 2647 MKKRVIDMAGCLGKNVKVELNGEDIRVRSFGDYCNLYLKSAFRIEEKVD--------RWE 2492
            M+KRVID+ GCLGK VKV+LN + I V+SF +YC L+L S     E +         RWE
Sbjct: 232  MRKRVIDLGGCLGKTVKVKLNEQRIPVKSFEEYCKLFLDSTDAKREFLKVTDADGLLRWE 291

Query: 2491 VCVSLSDGQFQQVSFVNSISTIKGGTHVDYVTNQIATHLAEYVNKKRKNANLKPHSVRNH 2312
            +CVSLS+GQFQQVSFVNSI+TIKGGTHVDYV NQIA+H+   VNKK KNAN+K H+V+NH
Sbjct: 292  ICVSLSEGQFQQVSFVNSIATIKGGTHVDYVANQIASHIMGVVNKKNKNANIKAHAVKNH 351

Query: 2311 LWVFVNCLIDNPAFDSQTKETLTLRQKSFGSECKLSDKFLSKVA-NSEIVNNILEWAEFK 2135
            LW+FVN LIDNPAFDSQTKETLTLRQ SFGS+C+L   FL KV  N  IV  +L WA+FK
Sbjct: 352  LWMFVNALIDNPAFDSQTKETLTLRQSSFGSKCELQQDFLKKVEKNIGIVETLLSWADFK 411

Query: 2134 EKKDLKKTDGTKSKRITGLTKLADANNAGGRNSEKCTLILTEGDSAATLAIAGLSVVGRD 1955
              KDLKKTDG KS+++  + KL DAN+AGGRNS+KCTLILTEGDSA  LA+AG+SVVGRD
Sbjct: 412  NSKDLKKTDGKKSEKVK-VEKLEDANDAGGRNSDKCTLILTEGDSAKALAMAGISVVGRD 470

Query: 1954 HYGVFPLRGKLLNVRDASTKQINDNAEIQNIKKILGLQHGKQYDSIKSLRYGHLMIMTDQ 1775
            HYGVFPLRGKLLNVR+AS KQ+++N EI+ IKKILGLQ GK+Y+S+KSLRYGHLMIMTDQ
Sbjct: 471  HYGVFPLRGKLLNVREASHKQVSENKEIEAIKKILGLQTGKEYESVKSLRYGHLMIMTDQ 530

Query: 1774 DHDGSHIKGLLINFIHSFWPSLLRIPSFLVEFITPIVKATHKNGEKRSFYTMPEYESWKE 1595
            DHDGSHIKGLLINFIH+FWPSLL++PSFL+EFITPIVKATHK+G+  SFYTMPEYESW++
Sbjct: 531  DHDGSHIKGLLINFIHTFWPSLLKVPSFLIEFITPIVKATHKSGKILSFYTMPEYESWRK 590

Query: 1594 SLGDKARSWSIKYYKGLGTSTDKEGKEYFKDLGKHKKDFVWADDHDGEAIELAFSKKKIE 1415
            SLG  +  WSIKYYKGLGTST KEGKEYF+DL KH+KDF+WAD+ DGE+IELAFSKKKIE
Sbjct: 591  SLGANSSGWSIKYYKGLGTSTSKEGKEYFQDLQKHRKDFIWADNQDGESIELAFSKKKIE 650

Query: 1414 ARKNWLRQFEPGTYLDQEDKLIKYRDFVNKELILFSIADLQRSIPSMVDGLKPGQRKILF 1235
            ARKNWLRQFEPGT+LDQ++K I Y +FVNKELILFS+ADLQRSIPSM+DGLKPGQRKILF
Sbjct: 651  ARKNWLRQFEPGTHLDQKEKYISYTEFVNKELILFSMADLQRSIPSMLDGLKPGQRKILF 710

Query: 1234 CAFKRNFVHEAKVGQFAGYVSEHSAYHHGEQSLASTIIGMAQQYVGSNNINILKPNGQFG 1055
            CAFKRNFV EAKV QF+GYVSEHSAYHHGEQSL+STIIGMAQ YVGSNN+N+L+PNGQFG
Sbjct: 711  CAFKRNFVKEAKVSQFSGYVSEHSAYHHGEQSLSSTIIGMAQDYVGSNNVNLLQPNGQFG 770

Query: 1054 TRNQGGKDHASARYIFTQLSAITRFLFPKDDDILLDYQNEDGQTIEPTWYVPIIPVVLVN 875
            TRN GGKDHAS+RYI+T+LS I RFLFPK+DD +LDY NEDGQ IEPTWYVPI+P+VL+N
Sbjct: 771  TRNMGGKDHASSRYIYTRLSPIARFLFPKEDDTILDYLNEDGQYIEPTWYVPIVPMVLIN 830

Query: 874  GSEGIGTGWSSFVPNYNPRDIIANVRHMLRDEPMEPMDPWYKGFRGTIEKTATKEAGATY 695
            GSEGIGTGWSS+VPNYNPRD++ANVR +L DEPMEPMDPWYKGF+GTIEKTATKEAGATY
Sbjct: 831  GSEGIGTGWSSYVPNYNPRDLVANVRRLLNDEPMEPMDPWYKGFKGTIEKTATKEAGATY 890

Query: 694  TVTGIIEEVSDTTLRVTELPVRKWTQDYKDFLESLY--------PFIEDVREYHTTDSVN 539
            TVTGIIEEV++TTLR++ELPVR+WT+DYK FLES+         PFI++VR Y   +SV 
Sbjct: 891  TVTGIIEEVNETTLRISELPVRRWTEDYKQFLESMTVSNDKAKDPFIKEVRAYGDENSVC 950

Query: 538  FEIDLSEENMRIAKQEGLLKKFKLTTTISTSNMHLFDSKGVIKKYDTPEKILEDFFSIRF 359
            FE+ +SEEN+ +A+QEGLLKKFKL TTISTSNMHLFDS G IKKYD PE ILE+F+ +R 
Sbjct: 951  FEVIMSEENLILAQQEGLLKKFKLATTISTSNMHLFDSNGKIKKYDNPEDILEEFYHVRL 1010

Query: 358  EFYEKRKKALMDNLERELLILENKVRFIMDVVEGKIVVSNRRRADLVLELKEKGFTPFPK 179
            E+YEKRKKAL++ LE ELL +ENKV+FI+ VV+G+I+V+NR+RADL+LELKEKGFTPFPK
Sbjct: 1011 EYYEKRKKALLEILELELLRIENKVKFILGVVKGEIIVNNRKRADLLLELKEKGFTPFPK 1070

Query: 178  KAKTTEISVAGSTDVPEETEENSDMATSQGVRASDYEYLLSMSIGSLTIEKVQELCNNR 2
            K K  E  VA ++D  E++EE      ++GVRA DY+YLLSM IG+LT+EKVQELC  R
Sbjct: 1071 K-KAVEAVVADTSDDAEDSEEE----LNRGVRAGDYDYLLSMPIGTLTLEKVQELCAER 1124