BLASTX 2.2.25 [Feb-01-2011]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= Forsythia23_contig00026553
         (2193 letters)

Database: ./nr 
           69,698,275 sequences; 24,982,196,650 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

ref|XP_011073926.1| PREDICTED: DNA topoisomerase 3-beta isoform ...   909   0.0  
ref|XP_011073927.1| PREDICTED: DNA topoisomerase 3-beta isoform ...   902   0.0  
ref|XP_011073925.1| PREDICTED: DNA topoisomerase 3-beta isoform ...   902   0.0  
ref|XP_009619602.1| PREDICTED: DNA topoisomerase 3-beta isoform ...   885   0.0  
ref|XP_009619600.1| PREDICTED: DNA topoisomerase 3-beta isoform ...   885   0.0  
ref|XP_009619599.1| PREDICTED: DNA topoisomerase 3-beta isoform ...   885   0.0  
ref|XP_009765589.1| PREDICTED: DNA topoisomerase 3-beta isoform ...   884   0.0  
ref|XP_009765588.1| PREDICTED: DNA topoisomerase 3-beta isoform ...   884   0.0  
ref|XP_009765587.1| PREDICTED: DNA topoisomerase 3-beta isoform ...   884   0.0  
ref|XP_006358794.1| PREDICTED: DNA topoisomerase 3-beta-1-like i...   883   0.0  
ref|XP_006358793.1| PREDICTED: DNA topoisomerase 3-beta-1-like i...   883   0.0  
ref|XP_010650402.1| PREDICTED: DNA topoisomerase 3-beta isoform ...   879   0.0  
ref|XP_010650401.1| PREDICTED: DNA topoisomerase 3-beta isoform ...   879   0.0  
ref|XP_010326952.1| PREDICTED: DNA topoisomerase 3-beta isoform ...   878   0.0  
ref|XP_004248022.1| PREDICTED: DNA topoisomerase 3-beta isoform ...   878   0.0  
ref|XP_002321105.1| DNA topoisomerase family protein [Populus tr...   875   0.0  
ref|XP_012455605.1| PREDICTED: DNA topoisomerase 3-beta isoform ...   874   0.0  
ref|XP_012455604.1| PREDICTED: DNA topoisomerase 3-beta isoform ...   874   0.0  
ref|XP_012455603.1| PREDICTED: DNA topoisomerase 3-beta isoform ...   874   0.0  
ref|XP_007034151.1| DNA topoisomerase, type IA, core [Theobroma ...   870   0.0  

>ref|XP_011073926.1| PREDICTED: DNA topoisomerase 3-beta isoform X2 [Sesamum indicum]
          Length = 865

 Score =  909 bits (2348), Expect(2) = 0.0
 Identities = 429/505 (84%), Positives = 461/505 (91%), Gaps = 11/505 (2%)
 Frame = -2

Query: 1484 ESTAYPPSFDFRGTLRALDNNPEWREYVQELLADGYVKPRSGNDAGDHPPITPMRSATQD 1305
            ESTAYP SFD++GTL AL  NP W +YVQ+LL+DGY KPRSG DAGDHPPITPM SAT++
Sbjct: 332  ESTAYPASFDYKGTLGALARNPVWGDYVQQLLSDGYHKPRSGTDAGDHPPITPMSSATEN 391

Query: 1304 MLGHDAWKLYQYVCQHFLGTLSPDTKYSRVKIEFAVAGELFQCIGQHVTVKGFASIMPWL 1125
            +LGHDAWKLYQY+CQHFLGTLSPD KY+R+KIEF   GE F C+GQHV VKGF SIMPWL
Sbjct: 392  ILGHDAWKLYQYICQHFLGTLSPDCKYTRIKIEFESGGESFYCVGQHVLVKGFTSIMPWL 451

Query: 1124 AVSEKSLPQFTQGEKIEISRIEVDEGNTAPPDYLTESELISLMEKNGIGTDASIPVHINN 945
            AV+E ++PQFT+G+KI+ISRIEVDEG+T PPDYL+ESELISLME+NGIGTDASIPVHINN
Sbjct: 452  AVTEINIPQFTEGQKIDISRIEVDEGSTQPPDYLSESELISLMEENGIGTDASIPVHINN 511

Query: 944  ICERNYVQVQAGRRLVPTALGVSLIRGYQCIDPDLCLPDIRSFIEHQITLVAKGQADHSL 765
            ICERNYVQVQAGRRLVPTALG+SLIRGYQ IDPDLCLPDIRSFIEHQI LVAKGQADHSL
Sbjct: 512  ICERNYVQVQAGRRLVPTALGISLIRGYQLIDPDLCLPDIRSFIEHQIALVAKGQADHSL 571

Query: 764  VVEHVIKQFKMKFSYFVKQIENMDALFEAEFSPLSDSGRFLSKCGKCLRYMRYISTQPSR 585
            VVEHVI+QFK KF YFVKQIENMDALFEAEFSPLSDSGR LSKCGKCLRYM++I TQPSR
Sbjct: 572  VVEHVIEQFKRKFIYFVKQIENMDALFEAEFSPLSDSGRVLSKCGKCLRYMKHIPTQPSR 631

Query: 584  LYCGTCEEIYYIPQKGTIKLYKELTCPLDNFELLIFSMPGPEGKSFPLCPYCYNCPPFEG 405
            LYCGTCEEIYY P KGTIKLYKELTCPLDNFELLIFSMPGPEGKSFP CPYCYN PPFEG
Sbjct: 632  LYCGTCEEIYYTPPKGTIKLYKELTCPLDNFELLIFSMPGPEGKSFPFCPYCYNNPPFEG 691

Query: 404  IDTLF--------VKSGKGAGMPCFLCPHPTCQHSMISQGVCACPECNGTLVLDPVSAPK 249
            ID LF        VK GKGAGMPCFLCPHPTCQHSMISQGVCACPEC+GTLVLDPVSAP+
Sbjct: 692  IDNLFGASKSSGSVKLGKGAGMPCFLCPHPTCQHSMISQGVCACPECDGTLVLDPVSAPR 751

Query: 248  WRLYCNMCNCLVFLPEGAHRISTTRDHCPECDSTIIEVDFNKKTTPLKDGATLHVGCVLC 69
            WRLYCNMCNCLV LPEGAHRISTTRDHCPECDSTIIEVDFNKKTTPLKDGATLH+GC+LC
Sbjct: 752  WRLYCNMCNCLVSLPEGAHRISTTRDHCPECDSTIIEVDFNKKTTPLKDGATLHIGCILC 811

Query: 68   DELLHSLVVMKYGRSFS---RHRGR 3
            DELL+SLV MK+G+SFS   RHRGR
Sbjct: 812  DELLYSLVEMKHGKSFSRKARHRGR 836



 Score =  431 bits (1108), Expect(2) = 0.0
 Identities = 209/243 (86%), Positives = 224/243 (92%)
 Frame = -1

Query: 2193 KAHICRHLNQEARGFGHLVLWLDCDREGENICFEVIECTGFHAKDGKRVYRARFSSVTEK 2014
            KAHICRHL+QEARG GHLVLWLDCDREGENICFEVIECTGF +  GK+V+RARFS+VTEK
Sbjct: 92   KAHICRHLSQEARGCGHLVLWLDCDREGENICFEVIECTGFQSTPGKKVHRARFSAVTEK 151

Query: 2013 DILKAMNNLVEPNKNEALAVDARQEIDLKVGVSFTRFQTSYFNGKYGNLDSRVISYGPCQ 1834
            DILKAMN+LVEPNKNEA AVDARQEIDLKVGV+FTRFQTSYFNGKYGNLDSRVISYGPCQ
Sbjct: 152  DILKAMNSLVEPNKNEAQAVDARQEIDLKVGVAFTRFQTSYFNGKYGNLDSRVISYGPCQ 211

Query: 1833 TPTLGFCVQRHLQIITFKPEKFWKLHPYILHKGYELKLEWNRNRLFDLDVTEMFRNIIKE 1654
            TPTLGFCV+RHLQI TFKPEKFW LHPYI++KGYELKL+W R+RLFD DVT+MFRN +KE
Sbjct: 212  TPTLGFCVRRHLQINTFKPEKFWTLHPYIMYKGYELKLDWQRHRLFDSDVTQMFRNFVKE 271

Query: 1653 DGILKVIAISEKQESKSRPAGLNTVNLLKVASSALGFGPQLAMQLAERLYTQGFISREYS 1474
            DG LKVI ISEKQ SK RP GLNTVNLLKVASSALGFGPQLAMQLAERLYTQGFIS   +
Sbjct: 272  DGFLKVIGISEKQVSKGRPTGLNTVNLLKVASSALGFGPQLAMQLAERLYTQGFISYPRT 331

Query: 1473 IST 1465
             ST
Sbjct: 332  EST 334


>ref|XP_011073927.1| PREDICTED: DNA topoisomerase 3-beta isoform X3 [Sesamum indicum]
          Length = 813

 Score =  902 bits (2330), Expect(2) = 0.0
 Identities = 429/512 (83%), Positives = 461/512 (90%), Gaps = 18/512 (3%)
 Frame = -2

Query: 1484 ESTAYPPSFDFRGTLRALDNNPEWREYVQELLADGYVKPRSGNDAGDHPPITPMRSATQD 1305
            ESTAYP SFD++GTL AL  NP W +YVQ+LL+DGY KPRSG DAGDHPPITPM SAT++
Sbjct: 273  ESTAYPASFDYKGTLGALARNPVWGDYVQQLLSDGYHKPRSGTDAGDHPPITPMSSATEN 332

Query: 1304 MLGHDAWKLYQYVCQHFLGTLSPDTKYSRVKIEFAVAGELFQCIGQHVTVKGFASIMPWL 1125
            +LGHDAWKLYQY+CQHFLGTLSPD KY+R+KIEF   GE F C+GQHV VKGF SIMPWL
Sbjct: 333  ILGHDAWKLYQYICQHFLGTLSPDCKYTRIKIEFESGGESFYCVGQHVLVKGFTSIMPWL 392

Query: 1124 AVSEKSLPQFTQGEKIEISRIEVDEGNTAPPDYLTESELISLMEKNGIGTDASIPVHINN 945
            AV+E ++PQFT+G+KI+ISRIEVDEG+T PPDYL+ESELISLME+NGIGTDASIPVHINN
Sbjct: 393  AVTEINIPQFTEGQKIDISRIEVDEGSTQPPDYLSESELISLMEENGIGTDASIPVHINN 452

Query: 944  ICERNYVQVQAGRRLVPTALGVSLIRGYQCIDPDLCLPDIRSFIEHQITLVAKGQADHSL 765
            ICERNYVQVQAGRRLVPTALG+SLIRGYQ IDPDLCLPDIRSFIEHQI LVAKGQADHSL
Sbjct: 453  ICERNYVQVQAGRRLVPTALGISLIRGYQLIDPDLCLPDIRSFIEHQIALVAKGQADHSL 512

Query: 764  VVEHVIKQFKMKFSYFVKQIENMDALFEAEFSPLSDSGRFLSKCGKCLRYMRYISTQPSR 585
            VVEHVI+QFK KF YFVKQIENMDALFEAEFSPLSDSGR LSKCGKCLRYM++I TQPSR
Sbjct: 513  VVEHVIEQFKRKFIYFVKQIENMDALFEAEFSPLSDSGRVLSKCGKCLRYMKHIPTQPSR 572

Query: 584  LYCGTCEEIYYIPQKGTIK-------LYKELTCPLDNFELLIFSMPGPEGKSFPLCPYCY 426
            LYCGTCEEIYY P KGTIK       LYKELTCPLDNFELLIFSMPGPEGKSFP CPYCY
Sbjct: 573  LYCGTCEEIYYTPPKGTIKVSHISPELYKELTCPLDNFELLIFSMPGPEGKSFPFCPYCY 632

Query: 425  NCPPFEGIDTLF--------VKSGKGAGMPCFLCPHPTCQHSMISQGVCACPECNGTLVL 270
            N PPFEGID LF        VK GKGAGMPCFLCPHPTCQHSMISQGVCACPEC+GTLVL
Sbjct: 633  NNPPFEGIDNLFGASKSSGSVKLGKGAGMPCFLCPHPTCQHSMISQGVCACPECDGTLVL 692

Query: 269  DPVSAPKWRLYCNMCNCLVFLPEGAHRISTTRDHCPECDSTIIEVDFNKKTTPLKDGATL 90
            DPVSAP+WRLYCNMCNCLV LPEGAHRISTTRDHCPECDSTIIEVDFNKKTTPLKDGATL
Sbjct: 693  DPVSAPRWRLYCNMCNCLVSLPEGAHRISTTRDHCPECDSTIIEVDFNKKTTPLKDGATL 752

Query: 89   HVGCVLCDELLHSLVVMKYGRSFS---RHRGR 3
            H+GC+LCDELL+SLV MK+G+SFS   RHRGR
Sbjct: 753  HIGCILCDELLYSLVEMKHGKSFSRKARHRGR 784



 Score =  431 bits (1108), Expect(2) = 0.0
 Identities = 209/243 (86%), Positives = 224/243 (92%)
 Frame = -1

Query: 2193 KAHICRHLNQEARGFGHLVLWLDCDREGENICFEVIECTGFHAKDGKRVYRARFSSVTEK 2014
            KAHICRHL+QEARG GHLVLWLDCDREGENICFEVIECTGF +  GK+V+RARFS+VTEK
Sbjct: 33   KAHICRHLSQEARGCGHLVLWLDCDREGENICFEVIECTGFQSTPGKKVHRARFSAVTEK 92

Query: 2013 DILKAMNNLVEPNKNEALAVDARQEIDLKVGVSFTRFQTSYFNGKYGNLDSRVISYGPCQ 1834
            DILKAMN+LVEPNKNEA AVDARQEIDLKVGV+FTRFQTSYFNGKYGNLDSRVISYGPCQ
Sbjct: 93   DILKAMNSLVEPNKNEAQAVDARQEIDLKVGVAFTRFQTSYFNGKYGNLDSRVISYGPCQ 152

Query: 1833 TPTLGFCVQRHLQIITFKPEKFWKLHPYILHKGYELKLEWNRNRLFDLDVTEMFRNIIKE 1654
            TPTLGFCV+RHLQI TFKPEKFW LHPYI++KGYELKL+W R+RLFD DVT+MFRN +KE
Sbjct: 153  TPTLGFCVRRHLQINTFKPEKFWTLHPYIMYKGYELKLDWQRHRLFDSDVTQMFRNFVKE 212

Query: 1653 DGILKVIAISEKQESKSRPAGLNTVNLLKVASSALGFGPQLAMQLAERLYTQGFISREYS 1474
            DG LKVI ISEKQ SK RP GLNTVNLLKVASSALGFGPQLAMQLAERLYTQGFIS   +
Sbjct: 213  DGFLKVIGISEKQVSKGRPTGLNTVNLLKVASSALGFGPQLAMQLAERLYTQGFISYPRT 272

Query: 1473 IST 1465
             ST
Sbjct: 273  EST 275


>ref|XP_011073925.1| PREDICTED: DNA topoisomerase 3-beta isoform X1 [Sesamum indicum]
          Length = 872

 Score =  902 bits (2330), Expect(2) = 0.0
 Identities = 429/512 (83%), Positives = 461/512 (90%), Gaps = 18/512 (3%)
 Frame = -2

Query: 1484 ESTAYPPSFDFRGTLRALDNNPEWREYVQELLADGYVKPRSGNDAGDHPPITPMRSATQD 1305
            ESTAYP SFD++GTL AL  NP W +YVQ+LL+DGY KPRSG DAGDHPPITPM SAT++
Sbjct: 332  ESTAYPASFDYKGTLGALARNPVWGDYVQQLLSDGYHKPRSGTDAGDHPPITPMSSATEN 391

Query: 1304 MLGHDAWKLYQYVCQHFLGTLSPDTKYSRVKIEFAVAGELFQCIGQHVTVKGFASIMPWL 1125
            +LGHDAWKLYQY+CQHFLGTLSPD KY+R+KIEF   GE F C+GQHV VKGF SIMPWL
Sbjct: 392  ILGHDAWKLYQYICQHFLGTLSPDCKYTRIKIEFESGGESFYCVGQHVLVKGFTSIMPWL 451

Query: 1124 AVSEKSLPQFTQGEKIEISRIEVDEGNTAPPDYLTESELISLMEKNGIGTDASIPVHINN 945
            AV+E ++PQFT+G+KI+ISRIEVDEG+T PPDYL+ESELISLME+NGIGTDASIPVHINN
Sbjct: 452  AVTEINIPQFTEGQKIDISRIEVDEGSTQPPDYLSESELISLMEENGIGTDASIPVHINN 511

Query: 944  ICERNYVQVQAGRRLVPTALGVSLIRGYQCIDPDLCLPDIRSFIEHQITLVAKGQADHSL 765
            ICERNYVQVQAGRRLVPTALG+SLIRGYQ IDPDLCLPDIRSFIEHQI LVAKGQADHSL
Sbjct: 512  ICERNYVQVQAGRRLVPTALGISLIRGYQLIDPDLCLPDIRSFIEHQIALVAKGQADHSL 571

Query: 764  VVEHVIKQFKMKFSYFVKQIENMDALFEAEFSPLSDSGRFLSKCGKCLRYMRYISTQPSR 585
            VVEHVI+QFK KF YFVKQIENMDALFEAEFSPLSDSGR LSKCGKCLRYM++I TQPSR
Sbjct: 572  VVEHVIEQFKRKFIYFVKQIENMDALFEAEFSPLSDSGRVLSKCGKCLRYMKHIPTQPSR 631

Query: 584  LYCGTCEEIYYIPQKGTIK-------LYKELTCPLDNFELLIFSMPGPEGKSFPLCPYCY 426
            LYCGTCEEIYY P KGTIK       LYKELTCPLDNFELLIFSMPGPEGKSFP CPYCY
Sbjct: 632  LYCGTCEEIYYTPPKGTIKVSHISPELYKELTCPLDNFELLIFSMPGPEGKSFPFCPYCY 691

Query: 425  NCPPFEGIDTLF--------VKSGKGAGMPCFLCPHPTCQHSMISQGVCACPECNGTLVL 270
            N PPFEGID LF        VK GKGAGMPCFLCPHPTCQHSMISQGVCACPEC+GTLVL
Sbjct: 692  NNPPFEGIDNLFGASKSSGSVKLGKGAGMPCFLCPHPTCQHSMISQGVCACPECDGTLVL 751

Query: 269  DPVSAPKWRLYCNMCNCLVFLPEGAHRISTTRDHCPECDSTIIEVDFNKKTTPLKDGATL 90
            DPVSAP+WRLYCNMCNCLV LPEGAHRISTTRDHCPECDSTIIEVDFNKKTTPLKDGATL
Sbjct: 752  DPVSAPRWRLYCNMCNCLVSLPEGAHRISTTRDHCPECDSTIIEVDFNKKTTPLKDGATL 811

Query: 89   HVGCVLCDELLHSLVVMKYGRSFS---RHRGR 3
            H+GC+LCDELL+SLV MK+G+SFS   RHRGR
Sbjct: 812  HIGCILCDELLYSLVEMKHGKSFSRKARHRGR 843



 Score =  431 bits (1108), Expect(2) = 0.0
 Identities = 209/243 (86%), Positives = 224/243 (92%)
 Frame = -1

Query: 2193 KAHICRHLNQEARGFGHLVLWLDCDREGENICFEVIECTGFHAKDGKRVYRARFSSVTEK 2014
            KAHICRHL+QEARG GHLVLWLDCDREGENICFEVIECTGF +  GK+V+RARFS+VTEK
Sbjct: 92   KAHICRHLSQEARGCGHLVLWLDCDREGENICFEVIECTGFQSTPGKKVHRARFSAVTEK 151

Query: 2013 DILKAMNNLVEPNKNEALAVDARQEIDLKVGVSFTRFQTSYFNGKYGNLDSRVISYGPCQ 1834
            DILKAMN+LVEPNKNEA AVDARQEIDLKVGV+FTRFQTSYFNGKYGNLDSRVISYGPCQ
Sbjct: 152  DILKAMNSLVEPNKNEAQAVDARQEIDLKVGVAFTRFQTSYFNGKYGNLDSRVISYGPCQ 211

Query: 1833 TPTLGFCVQRHLQIITFKPEKFWKLHPYILHKGYELKLEWNRNRLFDLDVTEMFRNIIKE 1654
            TPTLGFCV+RHLQI TFKPEKFW LHPYI++KGYELKL+W R+RLFD DVT+MFRN +KE
Sbjct: 212  TPTLGFCVRRHLQINTFKPEKFWTLHPYIMYKGYELKLDWQRHRLFDSDVTQMFRNFVKE 271

Query: 1653 DGILKVIAISEKQESKSRPAGLNTVNLLKVASSALGFGPQLAMQLAERLYTQGFISREYS 1474
            DG LKVI ISEKQ SK RP GLNTVNLLKVASSALGFGPQLAMQLAERLYTQGFIS   +
Sbjct: 272  DGFLKVIGISEKQVSKGRPTGLNTVNLLKVASSALGFGPQLAMQLAERLYTQGFISYPRT 331

Query: 1473 IST 1465
             ST
Sbjct: 332  EST 334


>ref|XP_009619602.1| PREDICTED: DNA topoisomerase 3-beta isoform X3 [Nicotiana
            tomentosiformis]
          Length = 805

 Score =  885 bits (2286), Expect(2) = 0.0
 Identities = 415/504 (82%), Positives = 452/504 (89%), Gaps = 10/504 (1%)
 Frame = -2

Query: 1484 ESTAYPPSFDFRGTLRALDNNPEWREYVQELLADGYVKPRSGNDAGDHPPITPMRSATQD 1305
            ESTAYP SFDF+GTL AL +NP +  Y Q+LL + Y KPR+G DAGDHPPITPMRSA++D
Sbjct: 273  ESTAYPSSFDFKGTLVALVHNPAFGGYAQKLLTESYNKPRAGTDAGDHPPITPMRSASED 332

Query: 1304 MLGHDAWKLYQYVCQHFLGTLSPDTKYSRVKIEFAVAGELFQCIGQHVTVKGFASIMPWL 1125
             LG+DAWKLYQY+CQHFLGTLSPD KY R+ +EF   GE FQCIGQ VTVKGF SIMPWL
Sbjct: 333  SLGNDAWKLYQYICQHFLGTLSPDCKYRRINVEFESGGEQFQCIGQLVTVKGFTSIMPWL 392

Query: 1124 AVSEKSLPQFTQGEKIEISRIEVDEGNTAPPDYLTESELISLMEKNGIGTDASIPVHINN 945
            AVSEK+LP F +GEKIEIS++++DEGNT+PPDYL ESELISLMEK+GIGTDASI VHINN
Sbjct: 393  AVSEKNLPDFAEGEKIEISKVDLDEGNTSPPDYLNESELISLMEKHGIGTDASISVHINN 452

Query: 944  ICERNYVQVQAGRRLVPTALGVSLIRGYQCIDPDLCLPDIRSFIEHQITLVAKGQADHSL 765
            ICERNYVQVQAGRRLVPT LG+SLIRGYQCID DLCLPDIRSFIEHQITLVAKGQADHS+
Sbjct: 453  ICERNYVQVQAGRRLVPTPLGISLIRGYQCIDSDLCLPDIRSFIEHQITLVAKGQADHSM 512

Query: 764  VVEHVIKQFKMKFSYFVKQIENMDALFEAEFSPLSDSGRFLSKCGKCLRYMRYISTQPSR 585
            VV+HV+ QF+ KFSYFVKQIENMDALFEA+FSPLSDSGR LSKCGKCLRYM+YISTQP R
Sbjct: 513  VVQHVLDQFRRKFSYFVKQIENMDALFEAQFSPLSDSGRLLSKCGKCLRYMKYISTQPPR 572

Query: 584  LYCGTCEEIYYIPQKGTIKLYKELTCPLDNFELLIFSMPGPEGKSFPLCPYCYNCPPFEG 405
            LYCGTCEE+YY+PQKGT+KLYKELTCPLDNFELL+  MPGPEGKSFPLCPYCYNCPPFEG
Sbjct: 573  LYCGTCEEVYYVPQKGTVKLYKELTCPLDNFELLLCIMPGPEGKSFPLCPYCYNCPPFEG 632

Query: 404  IDTLF--------VKSGKGAGMPCFLCPHPTCQHSMISQGVCACPECNGTLVLDPVSAPK 249
            IDT F         K GKG GMPCFLCPHPTC HS+I+QGVCACPEC+GTLVLDPVSAPK
Sbjct: 633  IDTFFGAPKTGDSSKLGKGVGMPCFLCPHPTCPHSVIAQGVCACPECSGTLVLDPVSAPK 692

Query: 248  WRLYCNMCNCLVFLPEGAHRISTTRDHCPECDSTIIEVDFNKKTTPLKDGATLHVGCVLC 69
            WRLYCNMCNCLV LPEGAHRISTT+D CPECDSTIIEVDFNKKTTPLKDGATLH GC+LC
Sbjct: 693  WRLYCNMCNCLVSLPEGAHRISTTQDKCPECDSTIIEVDFNKKTTPLKDGATLHKGCILC 752

Query: 68   DELLHSLVVMKYGRSFSRH--RGR 3
            DELLHSLV MK+GRSFSRH  RGR
Sbjct: 753  DELLHSLVEMKHGRSFSRHGRRGR 776



 Score =  418 bits (1075), Expect(2) = 0.0
 Identities = 199/243 (81%), Positives = 219/243 (90%)
 Frame = -1

Query: 2193 KAHICRHLNQEARGFGHLVLWLDCDREGENICFEVIECTGFHAKDGKRVYRARFSSVTEK 2014
            KAHICRHL+QEARG  HLVLWLDCDREGENICFEVIECTGFH  DG+R+YRARFSSVTEK
Sbjct: 33   KAHICRHLSQEARGCSHLVLWLDCDREGENICFEVIECTGFHTNDGRRIYRARFSSVTEK 92

Query: 2013 DILKAMNNLVEPNKNEALAVDARQEIDLKVGVSFTRFQTSYFNGKYGNLDSRVISYGPCQ 1834
            DILKAM++LVEPN++EALAVDARQEIDLKVGV+FTRFQTSYFNGKYGNLD+RVISYGPCQ
Sbjct: 93   DILKAMSSLVEPNRDEALAVDARQEIDLKVGVAFTRFQTSYFNGKYGNLDARVISYGPCQ 152

Query: 1833 TPTLGFCVQRHLQIITFKPEKFWKLHPYILHKGYELKLEWNRNRLFDLDVTEMFRNIIKE 1654
            TPTLGFCV R+LQI  FKPEKFW LHPYI++KGYELKLEW R RLFD DV  MFRN + E
Sbjct: 153  TPTLGFCVDRYLQIAMFKPEKFWMLHPYIMYKGYELKLEWERGRLFDADVAAMFRNRLME 212

Query: 1653 DGILKVIAISEKQESKSRPAGLNTVNLLKVASSALGFGPQLAMQLAERLYTQGFISREYS 1474
            DG ++V+ +SEK ESK RP+GLNTVNLLKVASSALGFGPQL MQLAERLYTQGF+S   +
Sbjct: 213  DGTMRVVRVSEKLESKGRPSGLNTVNLLKVASSALGFGPQLTMQLAERLYTQGFVSYPRT 272

Query: 1473 IST 1465
             ST
Sbjct: 273  EST 275


>ref|XP_009619600.1| PREDICTED: DNA topoisomerase 3-beta isoform X2 [Nicotiana
            tomentosiformis] gi|697131091|ref|XP_009619601.1|
            PREDICTED: DNA topoisomerase 3-beta isoform X2 [Nicotiana
            tomentosiformis]
          Length = 823

 Score =  885 bits (2286), Expect(2) = 0.0
 Identities = 415/504 (82%), Positives = 452/504 (89%), Gaps = 10/504 (1%)
 Frame = -2

Query: 1484 ESTAYPPSFDFRGTLRALDNNPEWREYVQELLADGYVKPRSGNDAGDHPPITPMRSATQD 1305
            ESTAYP SFDF+GTL AL +NP +  Y Q+LL + Y KPR+G DAGDHPPITPMRSA++D
Sbjct: 291  ESTAYPSSFDFKGTLVALVHNPAFGGYAQKLLTESYNKPRAGTDAGDHPPITPMRSASED 350

Query: 1304 MLGHDAWKLYQYVCQHFLGTLSPDTKYSRVKIEFAVAGELFQCIGQHVTVKGFASIMPWL 1125
             LG+DAWKLYQY+CQHFLGTLSPD KY R+ +EF   GE FQCIGQ VTVKGF SIMPWL
Sbjct: 351  SLGNDAWKLYQYICQHFLGTLSPDCKYRRINVEFESGGEQFQCIGQLVTVKGFTSIMPWL 410

Query: 1124 AVSEKSLPQFTQGEKIEISRIEVDEGNTAPPDYLTESELISLMEKNGIGTDASIPVHINN 945
            AVSEK+LP F +GEKIEIS++++DEGNT+PPDYL ESELISLMEK+GIGTDASI VHINN
Sbjct: 411  AVSEKNLPDFAEGEKIEISKVDLDEGNTSPPDYLNESELISLMEKHGIGTDASISVHINN 470

Query: 944  ICERNYVQVQAGRRLVPTALGVSLIRGYQCIDPDLCLPDIRSFIEHQITLVAKGQADHSL 765
            ICERNYVQVQAGRRLVPT LG+SLIRGYQCID DLCLPDIRSFIEHQITLVAKGQADHS+
Sbjct: 471  ICERNYVQVQAGRRLVPTPLGISLIRGYQCIDSDLCLPDIRSFIEHQITLVAKGQADHSM 530

Query: 764  VVEHVIKQFKMKFSYFVKQIENMDALFEAEFSPLSDSGRFLSKCGKCLRYMRYISTQPSR 585
            VV+HV+ QF+ KFSYFVKQIENMDALFEA+FSPLSDSGR LSKCGKCLRYM+YISTQP R
Sbjct: 531  VVQHVLDQFRRKFSYFVKQIENMDALFEAQFSPLSDSGRLLSKCGKCLRYMKYISTQPPR 590

Query: 584  LYCGTCEEIYYIPQKGTIKLYKELTCPLDNFELLIFSMPGPEGKSFPLCPYCYNCPPFEG 405
            LYCGTCEE+YY+PQKGT+KLYKELTCPLDNFELL+  MPGPEGKSFPLCPYCYNCPPFEG
Sbjct: 591  LYCGTCEEVYYVPQKGTVKLYKELTCPLDNFELLLCIMPGPEGKSFPLCPYCYNCPPFEG 650

Query: 404  IDTLF--------VKSGKGAGMPCFLCPHPTCQHSMISQGVCACPECNGTLVLDPVSAPK 249
            IDT F         K GKG GMPCFLCPHPTC HS+I+QGVCACPEC+GTLVLDPVSAPK
Sbjct: 651  IDTFFGAPKTGDSSKLGKGVGMPCFLCPHPTCPHSVIAQGVCACPECSGTLVLDPVSAPK 710

Query: 248  WRLYCNMCNCLVFLPEGAHRISTTRDHCPECDSTIIEVDFNKKTTPLKDGATLHVGCVLC 69
            WRLYCNMCNCLV LPEGAHRISTT+D CPECDSTIIEVDFNKKTTPLKDGATLH GC+LC
Sbjct: 711  WRLYCNMCNCLVSLPEGAHRISTTQDKCPECDSTIIEVDFNKKTTPLKDGATLHKGCILC 770

Query: 68   DELLHSLVVMKYGRSFSRH--RGR 3
            DELLHSLV MK+GRSFSRH  RGR
Sbjct: 771  DELLHSLVEMKHGRSFSRHGRRGR 794



 Score =  418 bits (1075), Expect(2) = 0.0
 Identities = 199/243 (81%), Positives = 219/243 (90%)
 Frame = -1

Query: 2193 KAHICRHLNQEARGFGHLVLWLDCDREGENICFEVIECTGFHAKDGKRVYRARFSSVTEK 2014
            KAHICRHL+QEARG  HLVLWLDCDREGENICFEVIECTGFH  DG+R+YRARFSSVTEK
Sbjct: 51   KAHICRHLSQEARGCSHLVLWLDCDREGENICFEVIECTGFHTNDGRRIYRARFSSVTEK 110

Query: 2013 DILKAMNNLVEPNKNEALAVDARQEIDLKVGVSFTRFQTSYFNGKYGNLDSRVISYGPCQ 1834
            DILKAM++LVEPN++EALAVDARQEIDLKVGV+FTRFQTSYFNGKYGNLD+RVISYGPCQ
Sbjct: 111  DILKAMSSLVEPNRDEALAVDARQEIDLKVGVAFTRFQTSYFNGKYGNLDARVISYGPCQ 170

Query: 1833 TPTLGFCVQRHLQIITFKPEKFWKLHPYILHKGYELKLEWNRNRLFDLDVTEMFRNIIKE 1654
            TPTLGFCV R+LQI  FKPEKFW LHPYI++KGYELKLEW R RLFD DV  MFRN + E
Sbjct: 171  TPTLGFCVDRYLQIAMFKPEKFWMLHPYIMYKGYELKLEWERGRLFDADVAAMFRNRLME 230

Query: 1653 DGILKVIAISEKQESKSRPAGLNTVNLLKVASSALGFGPQLAMQLAERLYTQGFISREYS 1474
            DG ++V+ +SEK ESK RP+GLNTVNLLKVASSALGFGPQL MQLAERLYTQGF+S   +
Sbjct: 231  DGTMRVVRVSEKLESKGRPSGLNTVNLLKVASSALGFGPQLTMQLAERLYTQGFVSYPRT 290

Query: 1473 IST 1465
             ST
Sbjct: 291  EST 293


>ref|XP_009619599.1| PREDICTED: DNA topoisomerase 3-beta isoform X1 [Nicotiana
            tomentosiformis]
          Length = 864

 Score =  885 bits (2286), Expect(2) = 0.0
 Identities = 415/504 (82%), Positives = 452/504 (89%), Gaps = 10/504 (1%)
 Frame = -2

Query: 1484 ESTAYPPSFDFRGTLRALDNNPEWREYVQELLADGYVKPRSGNDAGDHPPITPMRSATQD 1305
            ESTAYP SFDF+GTL AL +NP +  Y Q+LL + Y KPR+G DAGDHPPITPMRSA++D
Sbjct: 332  ESTAYPSSFDFKGTLVALVHNPAFGGYAQKLLTESYNKPRAGTDAGDHPPITPMRSASED 391

Query: 1304 MLGHDAWKLYQYVCQHFLGTLSPDTKYSRVKIEFAVAGELFQCIGQHVTVKGFASIMPWL 1125
             LG+DAWKLYQY+CQHFLGTLSPD KY R+ +EF   GE FQCIGQ VTVKGF SIMPWL
Sbjct: 392  SLGNDAWKLYQYICQHFLGTLSPDCKYRRINVEFESGGEQFQCIGQLVTVKGFTSIMPWL 451

Query: 1124 AVSEKSLPQFTQGEKIEISRIEVDEGNTAPPDYLTESELISLMEKNGIGTDASIPVHINN 945
            AVSEK+LP F +GEKIEIS++++DEGNT+PPDYL ESELISLMEK+GIGTDASI VHINN
Sbjct: 452  AVSEKNLPDFAEGEKIEISKVDLDEGNTSPPDYLNESELISLMEKHGIGTDASISVHINN 511

Query: 944  ICERNYVQVQAGRRLVPTALGVSLIRGYQCIDPDLCLPDIRSFIEHQITLVAKGQADHSL 765
            ICERNYVQVQAGRRLVPT LG+SLIRGYQCID DLCLPDIRSFIEHQITLVAKGQADHS+
Sbjct: 512  ICERNYVQVQAGRRLVPTPLGISLIRGYQCIDSDLCLPDIRSFIEHQITLVAKGQADHSM 571

Query: 764  VVEHVIKQFKMKFSYFVKQIENMDALFEAEFSPLSDSGRFLSKCGKCLRYMRYISTQPSR 585
            VV+HV+ QF+ KFSYFVKQIENMDALFEA+FSPLSDSGR LSKCGKCLRYM+YISTQP R
Sbjct: 572  VVQHVLDQFRRKFSYFVKQIENMDALFEAQFSPLSDSGRLLSKCGKCLRYMKYISTQPPR 631

Query: 584  LYCGTCEEIYYIPQKGTIKLYKELTCPLDNFELLIFSMPGPEGKSFPLCPYCYNCPPFEG 405
            LYCGTCEE+YY+PQKGT+KLYKELTCPLDNFELL+  MPGPEGKSFPLCPYCYNCPPFEG
Sbjct: 632  LYCGTCEEVYYVPQKGTVKLYKELTCPLDNFELLLCIMPGPEGKSFPLCPYCYNCPPFEG 691

Query: 404  IDTLF--------VKSGKGAGMPCFLCPHPTCQHSMISQGVCACPECNGTLVLDPVSAPK 249
            IDT F         K GKG GMPCFLCPHPTC HS+I+QGVCACPEC+GTLVLDPVSAPK
Sbjct: 692  IDTFFGAPKTGDSSKLGKGVGMPCFLCPHPTCPHSVIAQGVCACPECSGTLVLDPVSAPK 751

Query: 248  WRLYCNMCNCLVFLPEGAHRISTTRDHCPECDSTIIEVDFNKKTTPLKDGATLHVGCVLC 69
            WRLYCNMCNCLV LPEGAHRISTT+D CPECDSTIIEVDFNKKTTPLKDGATLH GC+LC
Sbjct: 752  WRLYCNMCNCLVSLPEGAHRISTTQDKCPECDSTIIEVDFNKKTTPLKDGATLHKGCILC 811

Query: 68   DELLHSLVVMKYGRSFSRH--RGR 3
            DELLHSLV MK+GRSFSRH  RGR
Sbjct: 812  DELLHSLVEMKHGRSFSRHGRRGR 835



 Score =  418 bits (1075), Expect(2) = 0.0
 Identities = 199/243 (81%), Positives = 219/243 (90%)
 Frame = -1

Query: 2193 KAHICRHLNQEARGFGHLVLWLDCDREGENICFEVIECTGFHAKDGKRVYRARFSSVTEK 2014
            KAHICRHL+QEARG  HLVLWLDCDREGENICFEVIECTGFH  DG+R+YRARFSSVTEK
Sbjct: 92   KAHICRHLSQEARGCSHLVLWLDCDREGENICFEVIECTGFHTNDGRRIYRARFSSVTEK 151

Query: 2013 DILKAMNNLVEPNKNEALAVDARQEIDLKVGVSFTRFQTSYFNGKYGNLDSRVISYGPCQ 1834
            DILKAM++LVEPN++EALAVDARQEIDLKVGV+FTRFQTSYFNGKYGNLD+RVISYGPCQ
Sbjct: 152  DILKAMSSLVEPNRDEALAVDARQEIDLKVGVAFTRFQTSYFNGKYGNLDARVISYGPCQ 211

Query: 1833 TPTLGFCVQRHLQIITFKPEKFWKLHPYILHKGYELKLEWNRNRLFDLDVTEMFRNIIKE 1654
            TPTLGFCV R+LQI  FKPEKFW LHPYI++KGYELKLEW R RLFD DV  MFRN + E
Sbjct: 212  TPTLGFCVDRYLQIAMFKPEKFWMLHPYIMYKGYELKLEWERGRLFDADVAAMFRNRLME 271

Query: 1653 DGILKVIAISEKQESKSRPAGLNTVNLLKVASSALGFGPQLAMQLAERLYTQGFISREYS 1474
            DG ++V+ +SEK ESK RP+GLNTVNLLKVASSALGFGPQL MQLAERLYTQGF+S   +
Sbjct: 272  DGTMRVVRVSEKLESKGRPSGLNTVNLLKVASSALGFGPQLTMQLAERLYTQGFVSYPRT 331

Query: 1473 IST 1465
             ST
Sbjct: 332  EST 334


>ref|XP_009765589.1| PREDICTED: DNA topoisomerase 3-beta isoform X3 [Nicotiana sylvestris]
          Length = 805

 Score =  884 bits (2283), Expect(2) = 0.0
 Identities = 415/506 (82%), Positives = 453/506 (89%), Gaps = 12/506 (2%)
 Frame = -2

Query: 1484 ESTAYPPSFDFRGTLRALDNNPEWREYVQELLADGYVKPRSGNDAGDHPPITPMRSATQD 1305
            ESTAYP SFDFRGTL AL +NP +  Y Q+LL + Y KPR+G DAGDHPPITPMRSA +D
Sbjct: 273  ESTAYPSSFDFRGTLVALVHNPVFGGYAQKLLTESYNKPRAGTDAGDHPPITPMRSAIED 332

Query: 1304 MLGHDAWKLYQYVCQHFLGTLSPDTKYSRVKIEFAVAGELFQCIGQHVTVKGFASIMPWL 1125
             LG+DAWKLYQY+CQHFLGTLSPD +Y R+K+EF   GE FQCIGQ VTVKGF SIMPWL
Sbjct: 333  SLGNDAWKLYQYICQHFLGTLSPDCRYRRIKVEFESGGEQFQCIGQLVTVKGFTSIMPWL 392

Query: 1124 AVSEKSLPQFTQGEKIEISRIEVDEGNTAPPDYLTESELISLMEKNGIGTDASIPVHINN 945
            A+SEK+LP F +GEKIEIS++++DEGNT+PPDYL ESELISLMEK+GIGTDASI VHINN
Sbjct: 393  AISEKNLPDFAEGEKIEISKVDLDEGNTSPPDYLNESELISLMEKHGIGTDASISVHINN 452

Query: 944  ICERNYVQVQAGRRLVPTALGVSLIRGYQCIDPDLCLPDIRSFIEHQITLVAKGQADHSL 765
            ICERNYVQVQAGRRLVPT LG+SLIRGYQCID DLCLPDIRSFIEHQITLVAKGQADHS+
Sbjct: 453  ICERNYVQVQAGRRLVPTPLGISLIRGYQCIDSDLCLPDIRSFIEHQITLVAKGQADHSM 512

Query: 764  VVEHVIKQFKMKFSYFVKQIENMDALFEAEFSPLSDSGRFLSKCGKCLRYMRYISTQPSR 585
            VV+HV+ QF+ KFSYFVKQIENMDALFEA+FSPLSDSGR LSKCGKCLRYM+YISTQPSR
Sbjct: 513  VVQHVLDQFRRKFSYFVKQIENMDALFEAQFSPLSDSGRLLSKCGKCLRYMKYISTQPSR 572

Query: 584  LYCGTCEEIYYIPQKGTIKLYKELTCPLDNFELLIFSMPGPEGKSFPLCPYCYNCPPFEG 405
            LYCGTCEE+YY+PQKGT+KLYKELTCPLDNFELL+ SMPGPEGKSFPLCPYCYNCPPFEG
Sbjct: 573  LYCGTCEEVYYVPQKGTVKLYKELTCPLDNFELLLCSMPGPEGKSFPLCPYCYNCPPFEG 632

Query: 404  IDTLF--------VKSGKGAGMPCFLCPHPTCQHSMISQGVCACPECNGTLVLDPVSAPK 249
            IDT F         K GKG GMPCFLCPHPTC HS+I+QGVCACPEC+GTLVLDPVSAPK
Sbjct: 633  IDTFFGAPKTGDSSKLGKGVGMPCFLCPHPTCPHSVIAQGVCACPECSGTLVLDPVSAPK 692

Query: 248  WRLYCNMCNCLVFLPEGAHRISTTRDHCPECDSTIIEVDFNKKTTPLKDGATLHVGCVLC 69
            WRL CNMCNCLV LPEGAHRISTT+D CPEC+STIIEVDFNKKTTPLKDGATLH GC+LC
Sbjct: 693  WRLCCNMCNCLVSLPEGAHRISTTQDKCPECESTIIEVDFNKKTTPLKDGATLHKGCILC 752

Query: 68   DELLHSLVVMKYGRSFSRH----RGR 3
            DELLHSLV MK+GRSFSRH    RGR
Sbjct: 753  DELLHSLVEMKHGRSFSRHGRSGRGR 778



 Score =  419 bits (1078), Expect(2) = 0.0
 Identities = 200/243 (82%), Positives = 219/243 (90%)
 Frame = -1

Query: 2193 KAHICRHLNQEARGFGHLVLWLDCDREGENICFEVIECTGFHAKDGKRVYRARFSSVTEK 2014
            KAHICRHL+QEARG  HLVLWLDCDREGENICFEVIECTGFH  DG+R+YRARFSSVTEK
Sbjct: 33   KAHICRHLSQEARGCSHLVLWLDCDREGENICFEVIECTGFHTSDGRRIYRARFSSVTEK 92

Query: 2013 DILKAMNNLVEPNKNEALAVDARQEIDLKVGVSFTRFQTSYFNGKYGNLDSRVISYGPCQ 1834
            DILKAMN+LV+PN++EALAVDARQEIDLKVGV+FTRFQTSYFNGKYGNLD+RVISYGPCQ
Sbjct: 93   DILKAMNSLVDPNRDEALAVDARQEIDLKVGVAFTRFQTSYFNGKYGNLDARVISYGPCQ 152

Query: 1833 TPTLGFCVQRHLQIITFKPEKFWKLHPYILHKGYELKLEWNRNRLFDLDVTEMFRNIIKE 1654
            TPTLGFCV R+LQI  FKPEKFW LHPYI++KGYELKLEW R RLFD DV  MFRN + E
Sbjct: 153  TPTLGFCVDRYLQITMFKPEKFWMLHPYIMYKGYELKLEWERGRLFDADVAAMFRNRLME 212

Query: 1653 DGILKVIAISEKQESKSRPAGLNTVNLLKVASSALGFGPQLAMQLAERLYTQGFISREYS 1474
            DG ++V+ +SEK ESK RP+GLNTVNLLKVASSALGFGPQL MQLAERLYTQGFIS   +
Sbjct: 213  DGTMRVVRVSEKLESKGRPSGLNTVNLLKVASSALGFGPQLTMQLAERLYTQGFISYPRT 272

Query: 1473 IST 1465
             ST
Sbjct: 273  EST 275


>ref|XP_009765588.1| PREDICTED: DNA topoisomerase 3-beta isoform X2 [Nicotiana sylvestris]
          Length = 815

 Score =  884 bits (2283), Expect(2) = 0.0
 Identities = 415/506 (82%), Positives = 453/506 (89%), Gaps = 12/506 (2%)
 Frame = -2

Query: 1484 ESTAYPPSFDFRGTLRALDNNPEWREYVQELLADGYVKPRSGNDAGDHPPITPMRSATQD 1305
            ESTAYP SFDFRGTL AL +NP +  Y Q+LL + Y KPR+G DAGDHPPITPMRSA +D
Sbjct: 283  ESTAYPSSFDFRGTLVALVHNPVFGGYAQKLLTESYNKPRAGTDAGDHPPITPMRSAIED 342

Query: 1304 MLGHDAWKLYQYVCQHFLGTLSPDTKYSRVKIEFAVAGELFQCIGQHVTVKGFASIMPWL 1125
             LG+DAWKLYQY+CQHFLGTLSPD +Y R+K+EF   GE FQCIGQ VTVKGF SIMPWL
Sbjct: 343  SLGNDAWKLYQYICQHFLGTLSPDCRYRRIKVEFESGGEQFQCIGQLVTVKGFTSIMPWL 402

Query: 1124 AVSEKSLPQFTQGEKIEISRIEVDEGNTAPPDYLTESELISLMEKNGIGTDASIPVHINN 945
            A+SEK+LP F +GEKIEIS++++DEGNT+PPDYL ESELISLMEK+GIGTDASI VHINN
Sbjct: 403  AISEKNLPDFAEGEKIEISKVDLDEGNTSPPDYLNESELISLMEKHGIGTDASISVHINN 462

Query: 944  ICERNYVQVQAGRRLVPTALGVSLIRGYQCIDPDLCLPDIRSFIEHQITLVAKGQADHSL 765
            ICERNYVQVQAGRRLVPT LG+SLIRGYQCID DLCLPDIRSFIEHQITLVAKGQADHS+
Sbjct: 463  ICERNYVQVQAGRRLVPTPLGISLIRGYQCIDSDLCLPDIRSFIEHQITLVAKGQADHSM 522

Query: 764  VVEHVIKQFKMKFSYFVKQIENMDALFEAEFSPLSDSGRFLSKCGKCLRYMRYISTQPSR 585
            VV+HV+ QF+ KFSYFVKQIENMDALFEA+FSPLSDSGR LSKCGKCLRYM+YISTQPSR
Sbjct: 523  VVQHVLDQFRRKFSYFVKQIENMDALFEAQFSPLSDSGRLLSKCGKCLRYMKYISTQPSR 582

Query: 584  LYCGTCEEIYYIPQKGTIKLYKELTCPLDNFELLIFSMPGPEGKSFPLCPYCYNCPPFEG 405
            LYCGTCEE+YY+PQKGT+KLYKELTCPLDNFELL+ SMPGPEGKSFPLCPYCYNCPPFEG
Sbjct: 583  LYCGTCEEVYYVPQKGTVKLYKELTCPLDNFELLLCSMPGPEGKSFPLCPYCYNCPPFEG 642

Query: 404  IDTLF--------VKSGKGAGMPCFLCPHPTCQHSMISQGVCACPECNGTLVLDPVSAPK 249
            IDT F         K GKG GMPCFLCPHPTC HS+I+QGVCACPEC+GTLVLDPVSAPK
Sbjct: 643  IDTFFGAPKTGDSSKLGKGVGMPCFLCPHPTCPHSVIAQGVCACPECSGTLVLDPVSAPK 702

Query: 248  WRLYCNMCNCLVFLPEGAHRISTTRDHCPECDSTIIEVDFNKKTTPLKDGATLHVGCVLC 69
            WRL CNMCNCLV LPEGAHRISTT+D CPEC+STIIEVDFNKKTTPLKDGATLH GC+LC
Sbjct: 703  WRLCCNMCNCLVSLPEGAHRISTTQDKCPECESTIIEVDFNKKTTPLKDGATLHKGCILC 762

Query: 68   DELLHSLVVMKYGRSFSRH----RGR 3
            DELLHSLV MK+GRSFSRH    RGR
Sbjct: 763  DELLHSLVEMKHGRSFSRHGRSGRGR 788



 Score =  419 bits (1078), Expect(2) = 0.0
 Identities = 200/243 (82%), Positives = 219/243 (90%)
 Frame = -1

Query: 2193 KAHICRHLNQEARGFGHLVLWLDCDREGENICFEVIECTGFHAKDGKRVYRARFSSVTEK 2014
            KAHICRHL+QEARG  HLVLWLDCDREGENICFEVIECTGFH  DG+R+YRARFSSVTEK
Sbjct: 43   KAHICRHLSQEARGCSHLVLWLDCDREGENICFEVIECTGFHTSDGRRIYRARFSSVTEK 102

Query: 2013 DILKAMNNLVEPNKNEALAVDARQEIDLKVGVSFTRFQTSYFNGKYGNLDSRVISYGPCQ 1834
            DILKAMN+LV+PN++EALAVDARQEIDLKVGV+FTRFQTSYFNGKYGNLD+RVISYGPCQ
Sbjct: 103  DILKAMNSLVDPNRDEALAVDARQEIDLKVGVAFTRFQTSYFNGKYGNLDARVISYGPCQ 162

Query: 1833 TPTLGFCVQRHLQIITFKPEKFWKLHPYILHKGYELKLEWNRNRLFDLDVTEMFRNIIKE 1654
            TPTLGFCV R+LQI  FKPEKFW LHPYI++KGYELKLEW R RLFD DV  MFRN + E
Sbjct: 163  TPTLGFCVDRYLQITMFKPEKFWMLHPYIMYKGYELKLEWERGRLFDADVAAMFRNRLME 222

Query: 1653 DGILKVIAISEKQESKSRPAGLNTVNLLKVASSALGFGPQLAMQLAERLYTQGFISREYS 1474
            DG ++V+ +SEK ESK RP+GLNTVNLLKVASSALGFGPQL MQLAERLYTQGFIS   +
Sbjct: 223  DGTMRVVRVSEKLESKGRPSGLNTVNLLKVASSALGFGPQLTMQLAERLYTQGFISYPRT 282

Query: 1473 IST 1465
             ST
Sbjct: 283  EST 285


>ref|XP_009765587.1| PREDICTED: DNA topoisomerase 3-beta isoform X1 [Nicotiana sylvestris]
          Length = 864

 Score =  884 bits (2283), Expect(2) = 0.0
 Identities = 415/506 (82%), Positives = 453/506 (89%), Gaps = 12/506 (2%)
 Frame = -2

Query: 1484 ESTAYPPSFDFRGTLRALDNNPEWREYVQELLADGYVKPRSGNDAGDHPPITPMRSATQD 1305
            ESTAYP SFDFRGTL AL +NP +  Y Q+LL + Y KPR+G DAGDHPPITPMRSA +D
Sbjct: 332  ESTAYPSSFDFRGTLVALVHNPVFGGYAQKLLTESYNKPRAGTDAGDHPPITPMRSAIED 391

Query: 1304 MLGHDAWKLYQYVCQHFLGTLSPDTKYSRVKIEFAVAGELFQCIGQHVTVKGFASIMPWL 1125
             LG+DAWKLYQY+CQHFLGTLSPD +Y R+K+EF   GE FQCIGQ VTVKGF SIMPWL
Sbjct: 392  SLGNDAWKLYQYICQHFLGTLSPDCRYRRIKVEFESGGEQFQCIGQLVTVKGFTSIMPWL 451

Query: 1124 AVSEKSLPQFTQGEKIEISRIEVDEGNTAPPDYLTESELISLMEKNGIGTDASIPVHINN 945
            A+SEK+LP F +GEKIEIS++++DEGNT+PPDYL ESELISLMEK+GIGTDASI VHINN
Sbjct: 452  AISEKNLPDFAEGEKIEISKVDLDEGNTSPPDYLNESELISLMEKHGIGTDASISVHINN 511

Query: 944  ICERNYVQVQAGRRLVPTALGVSLIRGYQCIDPDLCLPDIRSFIEHQITLVAKGQADHSL 765
            ICERNYVQVQAGRRLVPT LG+SLIRGYQCID DLCLPDIRSFIEHQITLVAKGQADHS+
Sbjct: 512  ICERNYVQVQAGRRLVPTPLGISLIRGYQCIDSDLCLPDIRSFIEHQITLVAKGQADHSM 571

Query: 764  VVEHVIKQFKMKFSYFVKQIENMDALFEAEFSPLSDSGRFLSKCGKCLRYMRYISTQPSR 585
            VV+HV+ QF+ KFSYFVKQIENMDALFEA+FSPLSDSGR LSKCGKCLRYM+YISTQPSR
Sbjct: 572  VVQHVLDQFRRKFSYFVKQIENMDALFEAQFSPLSDSGRLLSKCGKCLRYMKYISTQPSR 631

Query: 584  LYCGTCEEIYYIPQKGTIKLYKELTCPLDNFELLIFSMPGPEGKSFPLCPYCYNCPPFEG 405
            LYCGTCEE+YY+PQKGT+KLYKELTCPLDNFELL+ SMPGPEGKSFPLCPYCYNCPPFEG
Sbjct: 632  LYCGTCEEVYYVPQKGTVKLYKELTCPLDNFELLLCSMPGPEGKSFPLCPYCYNCPPFEG 691

Query: 404  IDTLF--------VKSGKGAGMPCFLCPHPTCQHSMISQGVCACPECNGTLVLDPVSAPK 249
            IDT F         K GKG GMPCFLCPHPTC HS+I+QGVCACPEC+GTLVLDPVSAPK
Sbjct: 692  IDTFFGAPKTGDSSKLGKGVGMPCFLCPHPTCPHSVIAQGVCACPECSGTLVLDPVSAPK 751

Query: 248  WRLYCNMCNCLVFLPEGAHRISTTRDHCPECDSTIIEVDFNKKTTPLKDGATLHVGCVLC 69
            WRL CNMCNCLV LPEGAHRISTT+D CPEC+STIIEVDFNKKTTPLKDGATLH GC+LC
Sbjct: 752  WRLCCNMCNCLVSLPEGAHRISTTQDKCPECESTIIEVDFNKKTTPLKDGATLHKGCILC 811

Query: 68   DELLHSLVVMKYGRSFSRH----RGR 3
            DELLHSLV MK+GRSFSRH    RGR
Sbjct: 812  DELLHSLVEMKHGRSFSRHGRSGRGR 837



 Score =  419 bits (1078), Expect(2) = 0.0
 Identities = 200/243 (82%), Positives = 219/243 (90%)
 Frame = -1

Query: 2193 KAHICRHLNQEARGFGHLVLWLDCDREGENICFEVIECTGFHAKDGKRVYRARFSSVTEK 2014
            KAHICRHL+QEARG  HLVLWLDCDREGENICFEVIECTGFH  DG+R+YRARFSSVTEK
Sbjct: 92   KAHICRHLSQEARGCSHLVLWLDCDREGENICFEVIECTGFHTSDGRRIYRARFSSVTEK 151

Query: 2013 DILKAMNNLVEPNKNEALAVDARQEIDLKVGVSFTRFQTSYFNGKYGNLDSRVISYGPCQ 1834
            DILKAMN+LV+PN++EALAVDARQEIDLKVGV+FTRFQTSYFNGKYGNLD+RVISYGPCQ
Sbjct: 152  DILKAMNSLVDPNRDEALAVDARQEIDLKVGVAFTRFQTSYFNGKYGNLDARVISYGPCQ 211

Query: 1833 TPTLGFCVQRHLQIITFKPEKFWKLHPYILHKGYELKLEWNRNRLFDLDVTEMFRNIIKE 1654
            TPTLGFCV R+LQI  FKPEKFW LHPYI++KGYELKLEW R RLFD DV  MFRN + E
Sbjct: 212  TPTLGFCVDRYLQITMFKPEKFWMLHPYIMYKGYELKLEWERGRLFDADVAAMFRNRLME 271

Query: 1653 DGILKVIAISEKQESKSRPAGLNTVNLLKVASSALGFGPQLAMQLAERLYTQGFISREYS 1474
            DG ++V+ +SEK ESK RP+GLNTVNLLKVASSALGFGPQL MQLAERLYTQGFIS   +
Sbjct: 272  DGTMRVVRVSEKLESKGRPSGLNTVNLLKVASSALGFGPQLTMQLAERLYTQGFISYPRT 331

Query: 1473 IST 1465
             ST
Sbjct: 332  EST 334


>ref|XP_006358794.1| PREDICTED: DNA topoisomerase 3-beta-1-like isoform X2 [Solanum
            tuberosum]
          Length = 801

 Score =  883 bits (2281), Expect(2) = 0.0
 Identities = 412/504 (81%), Positives = 453/504 (89%), Gaps = 10/504 (1%)
 Frame = -2

Query: 1484 ESTAYPPSFDFRGTLRALDNNPEWREYVQELLADGYVKPRSGNDAGDHPPITPMRSATQD 1305
            ESTAYP SFDF+GTL AL +NP +  Y Q+LL + Y KPR+G DAGDHPPITPMRSA++D
Sbjct: 273  ESTAYPSSFDFKGTLGALVHNPVFGAYAQKLLTESYNKPRAGTDAGDHPPITPMRSASED 332

Query: 1304 MLGHDAWKLYQYVCQHFLGTLSPDTKYSRVKIEFAVAGELFQCIGQHVTVKGFASIMPWL 1125
             LG+DAWKLYQY+CQHFLGTLSPD KY R+K+EF   GE FQC+GQ  TVKGF SIMPWL
Sbjct: 333  SLGNDAWKLYQYICQHFLGTLSPDCKYRRIKVEFESGGEQFQCVGQLATVKGFTSIMPWL 392

Query: 1124 AVSEKSLPQFTQGEKIEISRIEVDEGNTAPPDYLTESELISLMEKNGIGTDASIPVHINN 945
            A+SEK+LP+F  GEKIEIS+ E+DEGNT+PPDYLTESELISLMEK+GIGTDASI VHINN
Sbjct: 393  AISEKNLPEFAVGEKIEISKAELDEGNTSPPDYLTESELISLMEKHGIGTDASISVHINN 452

Query: 944  ICERNYVQVQAGRRLVPTALGVSLIRGYQCIDPDLCLPDIRSFIEHQITLVAKGQADHSL 765
            ICERNYVQVQAGRRL PT LG+SLIRGYQCID DLCLPDIRSFIEHQITLVAKGQADHS+
Sbjct: 453  ICERNYVQVQAGRRLAPTPLGISLIRGYQCIDSDLCLPDIRSFIEHQITLVAKGQADHSM 512

Query: 764  VVEHVIKQFKMKFSYFVKQIENMDALFEAEFSPLSDSGRFLSKCGKCLRYMRYISTQPSR 585
            VV+HV++QF+ KFSYFVKQI+NMDALFEA+FSPLSDSGR LSKCGKCLRYM+YISTQP+R
Sbjct: 513  VVQHVLEQFRRKFSYFVKQIDNMDALFEAQFSPLSDSGRLLSKCGKCLRYMKYISTQPAR 572

Query: 584  LYCGTCEEIYYIPQKGTIKLYKELTCPLDNFELLIFSMPGPEGKSFPLCPYCYNCPPFEG 405
            LYCGTCEE+YY+PQKGT+KLYKELTCPLDNFELL+ SMPGPEGKSFPLCPYC+NCPPFEG
Sbjct: 573  LYCGTCEEVYYVPQKGTVKLYKELTCPLDNFELLLCSMPGPEGKSFPLCPYCFNCPPFEG 632

Query: 404  IDTLF--------VKSGKGAGMPCFLCPHPTCQHSMISQGVCACPECNGTLVLDPVSAPK 249
            IDT F         K GKG GMPCFLCPH TC HS+I+QGVCACPEC+GTLVLDPVSAPK
Sbjct: 633  IDTFFGAPKTGDSTKLGKGVGMPCFLCPHTTCPHSVIAQGVCACPECSGTLVLDPVSAPK 692

Query: 248  WRLYCNMCNCLVFLPEGAHRISTTRDHCPECDSTIIEVDFNKKTTPLKDGATLHVGCVLC 69
            WRLYCNMCNCLV LPEGAHRISTT+D CPECDSTIIEVDFNKKTTPLKDGATLH GC+LC
Sbjct: 693  WRLYCNMCNCLVSLPEGAHRISTTQDKCPECDSTIIEVDFNKKTTPLKDGATLHKGCILC 752

Query: 68   DELLHSLVVMKYGRSFSRH--RGR 3
            DELLHSLV MK+GRSFSRH  RGR
Sbjct: 753  DELLHSLVEMKHGRSFSRHGRRGR 776



 Score =  422 bits (1085), Expect(2) = 0.0
 Identities = 204/243 (83%), Positives = 222/243 (91%)
 Frame = -1

Query: 2193 KAHICRHLNQEARGFGHLVLWLDCDREGENICFEVIECTGFHAKDGKRVYRARFSSVTEK 2014
            KAHICRHL+QEARG  HLVLWLDCDREGENI FEVIECTGFH  DG+R+YRARFSSVTEK
Sbjct: 33   KAHICRHLSQEARGCTHLVLWLDCDREGENISFEVIECTGFHTSDGRRIYRARFSSVTEK 92

Query: 2013 DILKAMNNLVEPNKNEALAVDARQEIDLKVGVSFTRFQTSYFNGKYGNLDSRVISYGPCQ 1834
            DILKAMNNLVEPN++EAL+VDARQEIDLKVGVSFTRFQTSYFNGKYGNLD+RVISYGPCQ
Sbjct: 93   DILKAMNNLVEPNRDEALSVDARQEIDLKVGVSFTRFQTSYFNGKYGNLDARVISYGPCQ 152

Query: 1833 TPTLGFCVQRHLQIITFKPEKFWKLHPYILHKGYELKLEWNRNRLFDLDVTEMFRNIIKE 1654
            TPTLGFCV R+LQI  FKPEKFW LHPYI++KGYELKLEW R+RLFD DV+ MFRN I E
Sbjct: 153  TPTLGFCVDRYLQITMFKPEKFWMLHPYIMYKGYELKLEWERSRLFDADVSAMFRNRIIE 212

Query: 1653 DGILKVIAISEKQESKSRPAGLNTVNLLKVASSALGFGPQLAMQLAERLYTQGFISREYS 1474
            DGI+KV+ +SEK ESK+RP+GLNTVNLLKVASSALGFGPQL MQLAERLYTQGFIS   +
Sbjct: 213  DGIMKVVRVSEKLESKARPSGLNTVNLLKVASSALGFGPQLTMQLAERLYTQGFISYPRT 272

Query: 1473 IST 1465
             ST
Sbjct: 273  EST 275


>ref|XP_006358793.1| PREDICTED: DNA topoisomerase 3-beta-1-like isoform X1 [Solanum
            tuberosum]
          Length = 860

 Score =  883 bits (2281), Expect(2) = 0.0
 Identities = 412/504 (81%), Positives = 453/504 (89%), Gaps = 10/504 (1%)
 Frame = -2

Query: 1484 ESTAYPPSFDFRGTLRALDNNPEWREYVQELLADGYVKPRSGNDAGDHPPITPMRSATQD 1305
            ESTAYP SFDF+GTL AL +NP +  Y Q+LL + Y KPR+G DAGDHPPITPMRSA++D
Sbjct: 332  ESTAYPSSFDFKGTLGALVHNPVFGAYAQKLLTESYNKPRAGTDAGDHPPITPMRSASED 391

Query: 1304 MLGHDAWKLYQYVCQHFLGTLSPDTKYSRVKIEFAVAGELFQCIGQHVTVKGFASIMPWL 1125
             LG+DAWKLYQY+CQHFLGTLSPD KY R+K+EF   GE FQC+GQ  TVKGF SIMPWL
Sbjct: 392  SLGNDAWKLYQYICQHFLGTLSPDCKYRRIKVEFESGGEQFQCVGQLATVKGFTSIMPWL 451

Query: 1124 AVSEKSLPQFTQGEKIEISRIEVDEGNTAPPDYLTESELISLMEKNGIGTDASIPVHINN 945
            A+SEK+LP+F  GEKIEIS+ E+DEGNT+PPDYLTESELISLMEK+GIGTDASI VHINN
Sbjct: 452  AISEKNLPEFAVGEKIEISKAELDEGNTSPPDYLTESELISLMEKHGIGTDASISVHINN 511

Query: 944  ICERNYVQVQAGRRLVPTALGVSLIRGYQCIDPDLCLPDIRSFIEHQITLVAKGQADHSL 765
            ICERNYVQVQAGRRL PT LG+SLIRGYQCID DLCLPDIRSFIEHQITLVAKGQADHS+
Sbjct: 512  ICERNYVQVQAGRRLAPTPLGISLIRGYQCIDSDLCLPDIRSFIEHQITLVAKGQADHSM 571

Query: 764  VVEHVIKQFKMKFSYFVKQIENMDALFEAEFSPLSDSGRFLSKCGKCLRYMRYISTQPSR 585
            VV+HV++QF+ KFSYFVKQI+NMDALFEA+FSPLSDSGR LSKCGKCLRYM+YISTQP+R
Sbjct: 572  VVQHVLEQFRRKFSYFVKQIDNMDALFEAQFSPLSDSGRLLSKCGKCLRYMKYISTQPAR 631

Query: 584  LYCGTCEEIYYIPQKGTIKLYKELTCPLDNFELLIFSMPGPEGKSFPLCPYCYNCPPFEG 405
            LYCGTCEE+YY+PQKGT+KLYKELTCPLDNFELL+ SMPGPEGKSFPLCPYC+NCPPFEG
Sbjct: 632  LYCGTCEEVYYVPQKGTVKLYKELTCPLDNFELLLCSMPGPEGKSFPLCPYCFNCPPFEG 691

Query: 404  IDTLF--------VKSGKGAGMPCFLCPHPTCQHSMISQGVCACPECNGTLVLDPVSAPK 249
            IDT F         K GKG GMPCFLCPH TC HS+I+QGVCACPEC+GTLVLDPVSAPK
Sbjct: 692  IDTFFGAPKTGDSTKLGKGVGMPCFLCPHTTCPHSVIAQGVCACPECSGTLVLDPVSAPK 751

Query: 248  WRLYCNMCNCLVFLPEGAHRISTTRDHCPECDSTIIEVDFNKKTTPLKDGATLHVGCVLC 69
            WRLYCNMCNCLV LPEGAHRISTT+D CPECDSTIIEVDFNKKTTPLKDGATLH GC+LC
Sbjct: 752  WRLYCNMCNCLVSLPEGAHRISTTQDKCPECDSTIIEVDFNKKTTPLKDGATLHKGCILC 811

Query: 68   DELLHSLVVMKYGRSFSRH--RGR 3
            DELLHSLV MK+GRSFSRH  RGR
Sbjct: 812  DELLHSLVEMKHGRSFSRHGRRGR 835



 Score =  422 bits (1085), Expect(2) = 0.0
 Identities = 204/243 (83%), Positives = 222/243 (91%)
 Frame = -1

Query: 2193 KAHICRHLNQEARGFGHLVLWLDCDREGENICFEVIECTGFHAKDGKRVYRARFSSVTEK 2014
            KAHICRHL+QEARG  HLVLWLDCDREGENI FEVIECTGFH  DG+R+YRARFSSVTEK
Sbjct: 92   KAHICRHLSQEARGCTHLVLWLDCDREGENISFEVIECTGFHTSDGRRIYRARFSSVTEK 151

Query: 2013 DILKAMNNLVEPNKNEALAVDARQEIDLKVGVSFTRFQTSYFNGKYGNLDSRVISYGPCQ 1834
            DILKAMNNLVEPN++EAL+VDARQEIDLKVGVSFTRFQTSYFNGKYGNLD+RVISYGPCQ
Sbjct: 152  DILKAMNNLVEPNRDEALSVDARQEIDLKVGVSFTRFQTSYFNGKYGNLDARVISYGPCQ 211

Query: 1833 TPTLGFCVQRHLQIITFKPEKFWKLHPYILHKGYELKLEWNRNRLFDLDVTEMFRNIIKE 1654
            TPTLGFCV R+LQI  FKPEKFW LHPYI++KGYELKLEW R+RLFD DV+ MFRN I E
Sbjct: 212  TPTLGFCVDRYLQITMFKPEKFWMLHPYIMYKGYELKLEWERSRLFDADVSAMFRNRIIE 271

Query: 1653 DGILKVIAISEKQESKSRPAGLNTVNLLKVASSALGFGPQLAMQLAERLYTQGFISREYS 1474
            DGI+KV+ +SEK ESK+RP+GLNTVNLLKVASSALGFGPQL MQLAERLYTQGFIS   +
Sbjct: 272  DGIMKVVRVSEKLESKARPSGLNTVNLLKVASSALGFGPQLTMQLAERLYTQGFISYPRT 331

Query: 1473 IST 1465
             ST
Sbjct: 332  EST 334


>ref|XP_010650402.1| PREDICTED: DNA topoisomerase 3-beta isoform X2 [Vitis vinifera]
          Length = 806

 Score =  879 bits (2270), Expect(2) = 0.0
 Identities = 408/507 (80%), Positives = 457/507 (90%), Gaps = 13/507 (2%)
 Frame = -2

Query: 1484 ESTAYPPSFDFRGTLRALDNNPEWREYVQELLADGYVKPRSGNDAGDHPPITPMRSATQD 1305
            ESTAYP SFDF+ TL    NNP W +YVQ+LL DG+ +PRSG DAGDHPPITPMR+A +D
Sbjct: 274  ESTAYPSSFDFKSTLGMQTNNPTWGDYVQKLLDDGFHRPRSGTDAGDHPPITPMRAANED 333

Query: 1304 MLGHDAWKLYQYVCQHFLGTLSPDTKYSRVKIEFAVAGELFQCIGQHVTVKGFASIMPWL 1125
            MLG+DAWKLYQYVCQHF+GT+SPD KY R K+EF++ GE+F+CIGQHV VKGF SIMPWL
Sbjct: 334  MLGNDAWKLYQYVCQHFIGTVSPDCKYVRNKVEFSIGGEIFRCIGQHVIVKGFTSIMPWL 393

Query: 1124 AVSEKSLPQFTQGEKIEISRIEVDEGNTAPPDYLTESELISLMEKNGIGTDASIPVHINN 945
            AV+EK+LPQF +GEKIE+S++E+ EG T+PPDYL+ESELISLMEKNGIGTDASIPVHINN
Sbjct: 394  AVNEKNLPQFKKGEKIEVSKVELYEGETSPPDYLSESELISLMEKNGIGTDASIPVHINN 453

Query: 944  ICERNYVQVQAGRRLVPTALGVSLIRGYQCIDPDLCLPDIRSFIEHQITLVAKGQADHSL 765
            ICERN+VQVQAGR+LVPTALG+SLIRGYQCIDPDLCLPDIRSFIE QITLVAKGQ DHS 
Sbjct: 454  ICERNFVQVQAGRKLVPTALGISLIRGYQCIDPDLCLPDIRSFIEQQITLVAKGQVDHSR 513

Query: 764  VVEHVIKQFKMKFSYFVKQIENMDALFEAEFSPLSDSGRFLSKCGKCLRYMRYISTQPSR 585
            VVEHV++QFK KF YFVKQIENMDALFEA+FSPL+DSGR LSKCGKCLRYM+YISTQPSR
Sbjct: 514  VVEHVLQQFKQKFIYFVKQIENMDALFEAQFSPLADSGRALSKCGKCLRYMKYISTQPSR 573

Query: 584  LYCGTCEEIYYIPQKGTIKLYKELTCPLDNFELLIFSMPGPEGKSFPLCPYCYNCPPFEG 405
            +YCGTCEE+YY+PQKGTIKLYKELTCPLDNFELLIFS+ GPEGKSFPLCPYCYN PPFEG
Sbjct: 574  MYCGTCEEVYYLPQKGTIKLYKELTCPLDNFELLIFSLAGPEGKSFPLCPYCYNSPPFEG 633

Query: 404  IDTLF--------VKSGKGAGMPCFLCPHPTCQHSMISQGVCACPECNGTLVLDPVSAPK 249
            IDTLF         K GKGAGMPCFLCPHPTC HS+I+QGVCACPEC+GTLVLDPVSAPK
Sbjct: 634  IDTLFGATKTSSTGKLGKGAGMPCFLCPHPTCPHSLIAQGVCACPECSGTLVLDPVSAPK 693

Query: 248  WRLYCNMCNCLVFLPEGAHRISTTRDHCPECDSTIIEVDFNKKTTPLKDGATLHVGCVLC 69
            WRLYCNMCNCLV+LP+GAH+ISTTRD CPEC+STI+EVDFNKKTTPL DG+TL+ GC+LC
Sbjct: 694  WRLYCNMCNCLVYLPQGAHKISTTRDRCPECESTILEVDFNKKTTPLLDGSTLYTGCILC 753

Query: 68   DELLHSLVVMKYGRSF-----SRHRGR 3
            DELLHSLV MK+G+SF     SR RGR
Sbjct: 754  DELLHSLVEMKHGKSFFKRMGSRGRGR 780



 Score =  412 bits (1060), Expect(2) = 0.0
 Identities = 202/244 (82%), Positives = 221/244 (90%), Gaps = 1/244 (0%)
 Frame = -1

Query: 2193 KAHICRHLNQEARGFGHLVLWLDCDREGENICFEVIECTGFHAKDGKR-VYRARFSSVTE 2017
            KAHI RHL+QEAR  GHLVLWLDCDREGENICFEV+ECTGFH  + +R VYRARFSSVTE
Sbjct: 33   KAHIRRHLSQEARDCGHLVLWLDCDREGENICFEVVECTGFHGNEARRRVYRARFSSVTE 92

Query: 2016 KDILKAMNNLVEPNKNEALAVDARQEIDLKVGVSFTRFQTSYFNGKYGNLDSRVISYGPC 1837
            KDILKAM+NLVEPN++EA AVDARQEIDLKVGV+FTRFQTSYF GKYGNLDSRVISYGPC
Sbjct: 93   KDILKAMDNLVEPNEDEARAVDARQEIDLKVGVAFTRFQTSYFQGKYGNLDSRVISYGPC 152

Query: 1836 QTPTLGFCVQRHLQIITFKPEKFWKLHPYILHKGYELKLEWNRNRLFDLDVTEMFRNIIK 1657
            QTPTLGFCVQR+LQI TFKPEKFW LHPYI H GYEL+LEW RN+LFDLDV  MF+N++ 
Sbjct: 153  QTPTLGFCVQRYLQINTFKPEKFWALHPYITHNGYELQLEWERNKLFDLDVAVMFQNLVM 212

Query: 1656 EDGILKVIAISEKQESKSRPAGLNTVNLLKVASSALGFGPQLAMQLAERLYTQGFISREY 1477
            EDGI++V  ISEKQESKSRP+GLNTVNLLKVASSALGFGPQ+AMQLAERLYTQGFIS   
Sbjct: 213  EDGIVEVTDISEKQESKSRPSGLNTVNLLKVASSALGFGPQMAMQLAERLYTQGFISYPR 272

Query: 1476 SIST 1465
            + ST
Sbjct: 273  TEST 276


>ref|XP_010650401.1| PREDICTED: DNA topoisomerase 3-beta isoform X1 [Vitis vinifera]
          Length = 871

 Score =  879 bits (2270), Expect(2) = 0.0
 Identities = 408/507 (80%), Positives = 457/507 (90%), Gaps = 13/507 (2%)
 Frame = -2

Query: 1484 ESTAYPPSFDFRGTLRALDNNPEWREYVQELLADGYVKPRSGNDAGDHPPITPMRSATQD 1305
            ESTAYP SFDF+ TL    NNP W +YVQ+LL DG+ +PRSG DAGDHPPITPMR+A +D
Sbjct: 339  ESTAYPSSFDFKSTLGMQTNNPTWGDYVQKLLDDGFHRPRSGTDAGDHPPITPMRAANED 398

Query: 1304 MLGHDAWKLYQYVCQHFLGTLSPDTKYSRVKIEFAVAGELFQCIGQHVTVKGFASIMPWL 1125
            MLG+DAWKLYQYVCQHF+GT+SPD KY R K+EF++ GE+F+CIGQHV VKGF SIMPWL
Sbjct: 399  MLGNDAWKLYQYVCQHFIGTVSPDCKYVRNKVEFSIGGEIFRCIGQHVIVKGFTSIMPWL 458

Query: 1124 AVSEKSLPQFTQGEKIEISRIEVDEGNTAPPDYLTESELISLMEKNGIGTDASIPVHINN 945
            AV+EK+LPQF +GEKIE+S++E+ EG T+PPDYL+ESELISLMEKNGIGTDASIPVHINN
Sbjct: 459  AVNEKNLPQFKKGEKIEVSKVELYEGETSPPDYLSESELISLMEKNGIGTDASIPVHINN 518

Query: 944  ICERNYVQVQAGRRLVPTALGVSLIRGYQCIDPDLCLPDIRSFIEHQITLVAKGQADHSL 765
            ICERN+VQVQAGR+LVPTALG+SLIRGYQCIDPDLCLPDIRSFIE QITLVAKGQ DHS 
Sbjct: 519  ICERNFVQVQAGRKLVPTALGISLIRGYQCIDPDLCLPDIRSFIEQQITLVAKGQVDHSR 578

Query: 764  VVEHVIKQFKMKFSYFVKQIENMDALFEAEFSPLSDSGRFLSKCGKCLRYMRYISTQPSR 585
            VVEHV++QFK KF YFVKQIENMDALFEA+FSPL+DSGR LSKCGKCLRYM+YISTQPSR
Sbjct: 579  VVEHVLQQFKQKFIYFVKQIENMDALFEAQFSPLADSGRALSKCGKCLRYMKYISTQPSR 638

Query: 584  LYCGTCEEIYYIPQKGTIKLYKELTCPLDNFELLIFSMPGPEGKSFPLCPYCYNCPPFEG 405
            +YCGTCEE+YY+PQKGTIKLYKELTCPLDNFELLIFS+ GPEGKSFPLCPYCYN PPFEG
Sbjct: 639  MYCGTCEEVYYLPQKGTIKLYKELTCPLDNFELLIFSLAGPEGKSFPLCPYCYNSPPFEG 698

Query: 404  IDTLF--------VKSGKGAGMPCFLCPHPTCQHSMISQGVCACPECNGTLVLDPVSAPK 249
            IDTLF         K GKGAGMPCFLCPHPTC HS+I+QGVCACPEC+GTLVLDPVSAPK
Sbjct: 699  IDTLFGATKTSSTGKLGKGAGMPCFLCPHPTCPHSLIAQGVCACPECSGTLVLDPVSAPK 758

Query: 248  WRLYCNMCNCLVFLPEGAHRISTTRDHCPECDSTIIEVDFNKKTTPLKDGATLHVGCVLC 69
            WRLYCNMCNCLV+LP+GAH+ISTTRD CPEC+STI+EVDFNKKTTPL DG+TL+ GC+LC
Sbjct: 759  WRLYCNMCNCLVYLPQGAHKISTTRDRCPECESTILEVDFNKKTTPLLDGSTLYTGCILC 818

Query: 68   DELLHSLVVMKYGRSF-----SRHRGR 3
            DELLHSLV MK+G+SF     SR RGR
Sbjct: 819  DELLHSLVEMKHGKSFFKRMGSRGRGR 845



 Score =  412 bits (1060), Expect(2) = 0.0
 Identities = 202/244 (82%), Positives = 221/244 (90%), Gaps = 1/244 (0%)
 Frame = -1

Query: 2193 KAHICRHLNQEARGFGHLVLWLDCDREGENICFEVIECTGFHAKDGKR-VYRARFSSVTE 2017
            KAHI RHL+QEAR  GHLVLWLDCDREGENICFEV+ECTGFH  + +R VYRARFSSVTE
Sbjct: 98   KAHIRRHLSQEARDCGHLVLWLDCDREGENICFEVVECTGFHGNEARRRVYRARFSSVTE 157

Query: 2016 KDILKAMNNLVEPNKNEALAVDARQEIDLKVGVSFTRFQTSYFNGKYGNLDSRVISYGPC 1837
            KDILKAM+NLVEPN++EA AVDARQEIDLKVGV+FTRFQTSYF GKYGNLDSRVISYGPC
Sbjct: 158  KDILKAMDNLVEPNEDEARAVDARQEIDLKVGVAFTRFQTSYFQGKYGNLDSRVISYGPC 217

Query: 1836 QTPTLGFCVQRHLQIITFKPEKFWKLHPYILHKGYELKLEWNRNRLFDLDVTEMFRNIIK 1657
            QTPTLGFCVQR+LQI TFKPEKFW LHPYI H GYEL+LEW RN+LFDLDV  MF+N++ 
Sbjct: 218  QTPTLGFCVQRYLQINTFKPEKFWALHPYITHNGYELQLEWERNKLFDLDVAVMFQNLVM 277

Query: 1656 EDGILKVIAISEKQESKSRPAGLNTVNLLKVASSALGFGPQLAMQLAERLYTQGFISREY 1477
            EDGI++V  ISEKQESKSRP+GLNTVNLLKVASSALGFGPQ+AMQLAERLYTQGFIS   
Sbjct: 278  EDGIVEVTDISEKQESKSRPSGLNTVNLLKVASSALGFGPQMAMQLAERLYTQGFISYPR 337

Query: 1476 SIST 1465
            + ST
Sbjct: 338  TEST 341


>ref|XP_010326952.1| PREDICTED: DNA topoisomerase 3-beta isoform X2 [Solanum lycopersicum]
          Length = 805

 Score =  878 bits (2268), Expect(2) = 0.0
 Identities = 407/504 (80%), Positives = 453/504 (89%), Gaps = 10/504 (1%)
 Frame = -2

Query: 1484 ESTAYPPSFDFRGTLRALDNNPEWREYVQELLADGYVKPRSGNDAGDHPPITPMRSATQD 1305
            ESTAYP SFDF+GTL AL +NP +  Y Q+LL D Y+KPR+G DAGDHPPITPMRSA++D
Sbjct: 273  ESTAYPSSFDFKGTLGALVHNPVFGAYAQKLLTDNYIKPRAGTDAGDHPPITPMRSASED 332

Query: 1304 MLGHDAWKLYQYVCQHFLGTLSPDTKYSRVKIEFAVAGELFQCIGQHVTVKGFASIMPWL 1125
             LG+DAWKLYQY+CQHFLGTLSPD KY R+K+EF   GE FQC+GQ  TVKGF SIMPWL
Sbjct: 333  SLGNDAWKLYQYICQHFLGTLSPDCKYRRIKVEFESGGEQFQCVGQLATVKGFTSIMPWL 392

Query: 1124 AVSEKSLPQFTQGEKIEISRIEVDEGNTAPPDYLTESELISLMEKNGIGTDASIPVHINN 945
            A+SEK+LP+F  GEKIE+S++E+DEG+T+PP YL+ESELISLMEK+GIGTDASI VHINN
Sbjct: 393  AISEKNLPEFAVGEKIEVSKVELDEGDTSPPGYLSESELISLMEKHGIGTDASISVHINN 452

Query: 944  ICERNYVQVQAGRRLVPTALGVSLIRGYQCIDPDLCLPDIRSFIEHQITLVAKGQADHSL 765
            ICERNYVQVQAGRRL PT LG+SLIRGYQCID DLCLPDIRSFIEHQITLVAKGQADHS+
Sbjct: 453  ICERNYVQVQAGRRLAPTPLGISLIRGYQCIDSDLCLPDIRSFIEHQITLVAKGQADHSM 512

Query: 764  VVEHVIKQFKMKFSYFVKQIENMDALFEAEFSPLSDSGRFLSKCGKCLRYMRYISTQPSR 585
            VV+HV++QF+ KFSYFVKQI+NMDALFEA+FSPLSDSGR LSKCGKCLRYM+YISTQP+R
Sbjct: 513  VVQHVLEQFRRKFSYFVKQIDNMDALFEAQFSPLSDSGRLLSKCGKCLRYMKYISTQPAR 572

Query: 584  LYCGTCEEIYYIPQKGTIKLYKELTCPLDNFELLIFSMPGPEGKSFPLCPYCYNCPPFEG 405
            LYCGTCEE+YY+PQKGT+KLYKELTCPLDNFELL+ SMPGPEGKSFPLCPYC+NCPPFEG
Sbjct: 573  LYCGTCEEVYYVPQKGTVKLYKELTCPLDNFELLLCSMPGPEGKSFPLCPYCFNCPPFEG 632

Query: 404  IDTLF--------VKSGKGAGMPCFLCPHPTCQHSMISQGVCACPECNGTLVLDPVSAPK 249
            IDT F         K GKG GMPCFLCPH TC HS+I+QGVCACPEC+GTLVLDPVSAPK
Sbjct: 633  IDTFFGAPKTGDSTKLGKGVGMPCFLCPHTTCPHSVIAQGVCACPECSGTLVLDPVSAPK 692

Query: 248  WRLYCNMCNCLVFLPEGAHRISTTRDHCPECDSTIIEVDFNKKTTPLKDGATLHVGCVLC 69
            WRLYCN CNCLV LPEGAHRISTT++ CPECDSTIIEVDFNKKTTPLKDGATLH GC+LC
Sbjct: 693  WRLYCNTCNCLVSLPEGAHRISTTQEKCPECDSTIIEVDFNKKTTPLKDGATLHKGCILC 752

Query: 68   DELLHSLVVMKYGRSFSRH--RGR 3
            DELLHSLV MK+GRSFSRH  RGR
Sbjct: 753  DELLHSLVEMKHGRSFSRHGRRGR 776



 Score =  417 bits (1072), Expect(2) = 0.0
 Identities = 201/243 (82%), Positives = 220/243 (90%)
 Frame = -1

Query: 2193 KAHICRHLNQEARGFGHLVLWLDCDREGENICFEVIECTGFHAKDGKRVYRARFSSVTEK 2014
            KAHICRHL+QEARG  HLVLWLDCDREGENICFEVIECTGFH  DG+R+YRARFSSVTEK
Sbjct: 33   KAHICRHLSQEARGCTHLVLWLDCDREGENICFEVIECTGFHTSDGRRIYRARFSSVTEK 92

Query: 2013 DILKAMNNLVEPNKNEALAVDARQEIDLKVGVSFTRFQTSYFNGKYGNLDSRVISYGPCQ 1834
            DILKAMN+L EPN++EAL+VDARQEIDLKVGV+FTRFQTSYFNGKYGNLD+RVISYGPCQ
Sbjct: 93   DILKAMNSLAEPNRDEALSVDARQEIDLKVGVAFTRFQTSYFNGKYGNLDARVISYGPCQ 152

Query: 1833 TPTLGFCVQRHLQIITFKPEKFWKLHPYILHKGYELKLEWNRNRLFDLDVTEMFRNIIKE 1654
            TPTLGFCV R LQI  FKPEKFW LHPYI++KGYELKLEW R+RLFD DV+ MFRN I E
Sbjct: 153  TPTLGFCVDRFLQITMFKPEKFWMLHPYIMYKGYELKLEWERSRLFDADVSAMFRNRIIE 212

Query: 1653 DGILKVIAISEKQESKSRPAGLNTVNLLKVASSALGFGPQLAMQLAERLYTQGFISREYS 1474
            D I+KV+ +SEK ESK+RP+GLNTVNLLKVASSALGFGPQL MQLAERLYTQGFIS   +
Sbjct: 213  DRIMKVVRVSEKLESKARPSGLNTVNLLKVASSALGFGPQLTMQLAERLYTQGFISYPRT 272

Query: 1473 IST 1465
             ST
Sbjct: 273  EST 275


>ref|XP_004248022.1| PREDICTED: DNA topoisomerase 3-beta isoform X1 [Solanum lycopersicum]
          Length = 864

 Score =  878 bits (2268), Expect(2) = 0.0
 Identities = 407/504 (80%), Positives = 453/504 (89%), Gaps = 10/504 (1%)
 Frame = -2

Query: 1484 ESTAYPPSFDFRGTLRALDNNPEWREYVQELLADGYVKPRSGNDAGDHPPITPMRSATQD 1305
            ESTAYP SFDF+GTL AL +NP +  Y Q+LL D Y+KPR+G DAGDHPPITPMRSA++D
Sbjct: 332  ESTAYPSSFDFKGTLGALVHNPVFGAYAQKLLTDNYIKPRAGTDAGDHPPITPMRSASED 391

Query: 1304 MLGHDAWKLYQYVCQHFLGTLSPDTKYSRVKIEFAVAGELFQCIGQHVTVKGFASIMPWL 1125
             LG+DAWKLYQY+CQHFLGTLSPD KY R+K+EF   GE FQC+GQ  TVKGF SIMPWL
Sbjct: 392  SLGNDAWKLYQYICQHFLGTLSPDCKYRRIKVEFESGGEQFQCVGQLATVKGFTSIMPWL 451

Query: 1124 AVSEKSLPQFTQGEKIEISRIEVDEGNTAPPDYLTESELISLMEKNGIGTDASIPVHINN 945
            A+SEK+LP+F  GEKIE+S++E+DEG+T+PP YL+ESELISLMEK+GIGTDASI VHINN
Sbjct: 452  AISEKNLPEFAVGEKIEVSKVELDEGDTSPPGYLSESELISLMEKHGIGTDASISVHINN 511

Query: 944  ICERNYVQVQAGRRLVPTALGVSLIRGYQCIDPDLCLPDIRSFIEHQITLVAKGQADHSL 765
            ICERNYVQVQAGRRL PT LG+SLIRGYQCID DLCLPDIRSFIEHQITLVAKGQADHS+
Sbjct: 512  ICERNYVQVQAGRRLAPTPLGISLIRGYQCIDSDLCLPDIRSFIEHQITLVAKGQADHSM 571

Query: 764  VVEHVIKQFKMKFSYFVKQIENMDALFEAEFSPLSDSGRFLSKCGKCLRYMRYISTQPSR 585
            VV+HV++QF+ KFSYFVKQI+NMDALFEA+FSPLSDSGR LSKCGKCLRYM+YISTQP+R
Sbjct: 572  VVQHVLEQFRRKFSYFVKQIDNMDALFEAQFSPLSDSGRLLSKCGKCLRYMKYISTQPAR 631

Query: 584  LYCGTCEEIYYIPQKGTIKLYKELTCPLDNFELLIFSMPGPEGKSFPLCPYCYNCPPFEG 405
            LYCGTCEE+YY+PQKGT+KLYKELTCPLDNFELL+ SMPGPEGKSFPLCPYC+NCPPFEG
Sbjct: 632  LYCGTCEEVYYVPQKGTVKLYKELTCPLDNFELLLCSMPGPEGKSFPLCPYCFNCPPFEG 691

Query: 404  IDTLF--------VKSGKGAGMPCFLCPHPTCQHSMISQGVCACPECNGTLVLDPVSAPK 249
            IDT F         K GKG GMPCFLCPH TC HS+I+QGVCACPEC+GTLVLDPVSAPK
Sbjct: 692  IDTFFGAPKTGDSTKLGKGVGMPCFLCPHTTCPHSVIAQGVCACPECSGTLVLDPVSAPK 751

Query: 248  WRLYCNMCNCLVFLPEGAHRISTTRDHCPECDSTIIEVDFNKKTTPLKDGATLHVGCVLC 69
            WRLYCN CNCLV LPEGAHRISTT++ CPECDSTIIEVDFNKKTTPLKDGATLH GC+LC
Sbjct: 752  WRLYCNTCNCLVSLPEGAHRISTTQEKCPECDSTIIEVDFNKKTTPLKDGATLHKGCILC 811

Query: 68   DELLHSLVVMKYGRSFSRH--RGR 3
            DELLHSLV MK+GRSFSRH  RGR
Sbjct: 812  DELLHSLVEMKHGRSFSRHGRRGR 835



 Score =  417 bits (1072), Expect(2) = 0.0
 Identities = 201/243 (82%), Positives = 220/243 (90%)
 Frame = -1

Query: 2193 KAHICRHLNQEARGFGHLVLWLDCDREGENICFEVIECTGFHAKDGKRVYRARFSSVTEK 2014
            KAHICRHL+QEARG  HLVLWLDCDREGENICFEVIECTGFH  DG+R+YRARFSSVTEK
Sbjct: 92   KAHICRHLSQEARGCTHLVLWLDCDREGENICFEVIECTGFHTSDGRRIYRARFSSVTEK 151

Query: 2013 DILKAMNNLVEPNKNEALAVDARQEIDLKVGVSFTRFQTSYFNGKYGNLDSRVISYGPCQ 1834
            DILKAMN+L EPN++EAL+VDARQEIDLKVGV+FTRFQTSYFNGKYGNLD+RVISYGPCQ
Sbjct: 152  DILKAMNSLAEPNRDEALSVDARQEIDLKVGVAFTRFQTSYFNGKYGNLDARVISYGPCQ 211

Query: 1833 TPTLGFCVQRHLQIITFKPEKFWKLHPYILHKGYELKLEWNRNRLFDLDVTEMFRNIIKE 1654
            TPTLGFCV R LQI  FKPEKFW LHPYI++KGYELKLEW R+RLFD DV+ MFRN I E
Sbjct: 212  TPTLGFCVDRFLQITMFKPEKFWMLHPYIMYKGYELKLEWERSRLFDADVSAMFRNRIIE 271

Query: 1653 DGILKVIAISEKQESKSRPAGLNTVNLLKVASSALGFGPQLAMQLAERLYTQGFISREYS 1474
            D I+KV+ +SEK ESK+RP+GLNTVNLLKVASSALGFGPQL MQLAERLYTQGFIS   +
Sbjct: 272  DRIMKVVRVSEKLESKARPSGLNTVNLLKVASSALGFGPQLTMQLAERLYTQGFISYPRT 331

Query: 1473 IST 1465
             ST
Sbjct: 332  EST 334


>ref|XP_002321105.1| DNA topoisomerase family protein [Populus trichocarpa]
            gi|222861878|gb|EEE99420.1| DNA topoisomerase family
            protein [Populus trichocarpa]
          Length = 837

 Score =  875 bits (2262), Expect(2) = 0.0
 Identities = 403/502 (80%), Positives = 451/502 (89%), Gaps = 8/502 (1%)
 Frame = -2

Query: 1484 ESTAYPPSFDFRGTLRALDNNPEWREYVQELLADGYVKPRSGNDAGDHPPITPMRSATQD 1305
            ESTAYP SFDF+GTL AL NNP W +YVQ LL+ GY KP+SG DAGDHPPITPMRSA +D
Sbjct: 307  ESTAYPSSFDFKGTLGALANNPMWGDYVQGLLSGGYHKPQSGKDAGDHPPITPMRSANED 366

Query: 1304 MLGHDAWKLYQYVCQHFLGTLSPDTKYSRVKIEFAVAGELFQCIGQHVTVKGFASIMPWL 1125
            MLG DAW+LYQYVCQHFLGT+SPD KY+R K+EF++ GE F CIG HVTVKGF SIMPWL
Sbjct: 367  MLGRDAWRLYQYVCQHFLGTVSPDCKYTRTKVEFSIGGEFFHCIGLHVTVKGFTSIMPWL 426

Query: 1124 AVSEKSLPQFTQGEKIEISRIEVDEGNTAPPDYLTESELISLMEKNGIGTDASIPVHINN 945
            AVSEK+LPQF +G+KIE+S++E+ EG T PPDYL+ESELISLMEKNGIGTDASI VHINN
Sbjct: 427  AVSEKNLPQFAKGDKIEVSKVELFEGQTVPPDYLSESELISLMEKNGIGTDASISVHINN 486

Query: 944  ICERNYVQVQAGRRLVPTALGVSLIRGYQCIDPDLCLPDIRSFIEHQITLVAKGQADHSL 765
            ICERNYVQVQAGR+LVPTALG++LIRGYQCIDPDLCLPDIR FIE QITLVAKG+ADHS 
Sbjct: 487  ICERNYVQVQAGRKLVPTALGITLIRGYQCIDPDLCLPDIRGFIEQQITLVAKGEADHSC 546

Query: 764  VVEHVIKQFKMKFSYFVKQIENMDALFEAEFSPLSDSGRFLSKCGKCLRYMRYISTQPSR 585
            VV+HV++QFK K+SYFVKQI+NMDALFEA+FSPL+DSGR  SKCGKCLRYM+YIS+QPSR
Sbjct: 547  VVQHVLEQFKRKYSYFVKQIDNMDALFEAQFSPLADSGRAFSKCGKCLRYMKYISSQPSR 606

Query: 584  LYCGTCEEIYYIPQKGTIKLYKELTCPLDNFELLIFSMPGPEGKSFPLCPYCYNCPPFEG 405
            LYCGTCEE+YY+PQKGTIKLYKELTCPLDNFELLIF+M GPEGKSFPLCP CYN PPFEG
Sbjct: 607  LYCGTCEEVYYLPQKGTIKLYKELTCPLDNFELLIFAMAGPEGKSFPLCPLCYNSPPFEG 666

Query: 404  IDTLFVKS--------GKGAGMPCFLCPHPTCQHSMISQGVCACPECNGTLVLDPVSAPK 249
            ID LF  S        GKGAGMPCFLCPHPTC+HS+I+QGVCACPECNGTLVLDP+SAPK
Sbjct: 667  IDALFGASKTGSSGMLGKGAGMPCFLCPHPTCRHSLIAQGVCACPECNGTLVLDPISAPK 726

Query: 248  WRLYCNMCNCLVFLPEGAHRISTTRDHCPECDSTIIEVDFNKKTTPLKDGATLHVGCVLC 69
            WRLYCNMCNCLV LP+GAHRISTTR+ CPECDSTIIEVDFNK TTPL+DGATLHVGC+LC
Sbjct: 727  WRLYCNMCNCLVLLPQGAHRISTTREQCPECDSTIIEVDFNKNTTPLEDGATLHVGCILC 786

Query: 68   DELLHSLVVMKYGRSFSRHRGR 3
            D LLHSLV +K+G+SF +  G+
Sbjct: 787  DNLLHSLVEVKHGKSFFKRAGK 808



 Score =  390 bits (1002), Expect(2) = 0.0
 Identities = 192/244 (78%), Positives = 214/244 (87%), Gaps = 1/244 (0%)
 Frame = -1

Query: 2193 KAHICRHLNQEARGFGHLVLWLDCDREGENICFEVIECTGFHAKDGKR-VYRARFSSVTE 2017
            KAHICRHL+QEARG  HLVLWLDCDREGENICFEVI+CTGF A D +R VYRARFSSVTE
Sbjct: 66   KAHICRHLSQEARGCNHLVLWLDCDREGENICFEVIQCTGFQANDDRRKVYRARFSSVTE 125

Query: 2016 KDILKAMNNLVEPNKNEALAVDARQEIDLKVGVSFTRFQTSYFNGKYGNLDSRVISYGPC 1837
            KDILKAMN LVEPN+ EALAVDARQEIDLKVGV+FTRFQTS+F GKYGNLDSRVISYGPC
Sbjct: 126  KDILKAMNCLVEPNEYEALAVDARQEIDLKVGVAFTRFQTSFFQGKYGNLDSRVISYGPC 185

Query: 1836 QTPTLGFCVQRHLQIITFKPEKFWKLHPYILHKGYELKLEWNRNRLFDLDVTEMFRNIIK 1657
            QTPTLGFCVQR+LQI TFKPEKFW L P+++  GYEL+LEW R++LFDLDV  MF+ ++ 
Sbjct: 186  QTPTLGFCVQRYLQITTFKPEKFWALRPHVMVDGYELQLEWERHKLFDLDVALMFQKLVL 245

Query: 1656 EDGILKVIAISEKQESKSRPAGLNTVNLLKVASSALGFGPQLAMQLAERLYTQGFISREY 1477
            +D IL+V  +SEKQESK RP GLNTVNLLK+ASSALGFGPQ+ MQLAERLY QGFIS   
Sbjct: 246  QDRILEVTDMSEKQESKGRPPGLNTVNLLKIASSALGFGPQVTMQLAERLYIQGFISYPR 305

Query: 1476 SIST 1465
            + ST
Sbjct: 306  TEST 309


>ref|XP_012455605.1| PREDICTED: DNA topoisomerase 3-beta isoform X3 [Gossypium raimondii]
          Length = 781

 Score =  874 bits (2258), Expect(2) = 0.0
 Identities = 400/501 (79%), Positives = 452/501 (90%), Gaps = 8/501 (1%)
 Frame = -2

Query: 1484 ESTAYPPSFDFRGTLRALDNNPEWREYVQELLADGYVKPRSGNDAGDHPPITPMRSATQD 1305
            ESTAYP SFDF+GTL+ L+NNP W + VQ LLA+GY KPR+G DAGDHPPITPMR AT+D
Sbjct: 244  ESTAYPSSFDFKGTLKVLENNPSWSDCVQRLLAEGYHKPRTGTDAGDHPPITPMRPATED 303

Query: 1304 MLGHDAWKLYQYVCQHFLGTLSPDTKYSRVKIEFAVAGELFQCIGQHVTVKGFASIMPWL 1125
            +LG+DAW+LYQY+CQHF+GT+SPD KY R K+EF++ GE F CIGQ VTV+GF  IMPWL
Sbjct: 304  VLGNDAWRLYQYICQHFMGTVSPDCKYVRTKVEFSIGGEFFHCIGQRVTVQGFTYIMPWL 363

Query: 1124 AVSEKSLPQFTQGEKIEISRIEVDEGNTAPPDYLTESELISLMEKNGIGTDASIPVHINN 945
            A++EK+LPQFT+GEKIE+SR+E+ EG T+PPDYL+ESELISLMEKNGIGTDASIPVHINN
Sbjct: 364  AINEKNLPQFTKGEKIEVSRVELYEGETSPPDYLSESELISLMEKNGIGTDASIPVHINN 423

Query: 944  ICERNYVQVQAGRRLVPTALGVSLIRGYQCIDPDLCLPDIRSFIEHQITLVAKGQADHSL 765
            ICERNYVQVQAGRRLVPT LG++LIRGYQCIDPDLCLPDIRSFIEHQITLVAKGQA+H  
Sbjct: 424  ICERNYVQVQAGRRLVPTTLGITLIRGYQCIDPDLCLPDIRSFIEHQITLVAKGQANHFR 483

Query: 764  VVEHVIKQFKMKFSYFVKQIENMDALFEAEFSPLSDSGRFLSKCGKCLRYMRYISTQPSR 585
            VV+HV++QFK KF YF++QIENMDALFEA+FSPL+DSGR LSKCGKCLRYM+YIS QP R
Sbjct: 484  VVQHVLQQFKQKFCYFLQQIENMDALFEAQFSPLADSGRALSKCGKCLRYMKYISAQPQR 543

Query: 584  LYCGTCEEIYYIPQKGTIKLYKELTCPLDNFELLIFSMPGPEGKSFPLCPYCYNCPPFEG 405
            ++CGTCEE+YY+PQKGTIKLYKELTCPLDNFELLIFSMPGPEGKSFPLCPYCYN PPFEG
Sbjct: 544  MFCGTCEEVYYLPQKGTIKLYKELTCPLDNFELLIFSMPGPEGKSFPLCPYCYNSPPFEG 603

Query: 404  IDTLF--------VKSGKGAGMPCFLCPHPTCQHSMISQGVCACPECNGTLVLDPVSAPK 249
            IDTLF         K GKGAGMPCFLC HPTC+HS+++QGVCACPEC+GTLVLDPVSAPK
Sbjct: 604  IDTLFGSAKIGSTGKLGKGAGMPCFLCLHPTCRHSVVAQGVCACPECSGTLVLDPVSAPK 663

Query: 248  WRLYCNMCNCLVFLPEGAHRISTTRDHCPECDSTIIEVDFNKKTTPLKDGATLHVGCVLC 69
            WRLYCN CNCLV LPEGAHRI+TTRD C ECDSTIIEVDFNKKTTPL+DGATLH GC+LC
Sbjct: 664  WRLYCNKCNCLVLLPEGAHRIATTRDRCAECDSTIIEVDFNKKTTPLEDGATLHTGCILC 723

Query: 68   DELLHSLVVMKYGRSFSRHRG 6
            DELLHSLV +K+G+SF R  G
Sbjct: 724  DELLHSLVEVKHGKSFGRGFG 744



 Score =  394 bits (1012), Expect(2) = 0.0
 Identities = 193/243 (79%), Positives = 216/243 (88%), Gaps = 1/243 (0%)
 Frame = -1

Query: 2190 AHICRHLNQEARGFGHLVLWLDCDREGENICFEVIECTGFHAKDGK-RVYRARFSSVTEK 2014
            AHI +HL+QEARG G+LVLWLDCDREGENICFEVIECT F   + K RVYRARFSSVTEK
Sbjct: 4    AHISKHLSQEARGCGYLVLWLDCDREGENICFEVIECTRFPMNEAKKRVYRARFSSVTEK 63

Query: 2013 DILKAMNNLVEPNKNEALAVDARQEIDLKVGVSFTRFQTSYFNGKYGNLDSRVISYGPCQ 1834
            DILKAM+NLVEPN++EALAVDARQEIDLKVGV+FTRFQTSYF GKYGNLDSRVISYGPCQ
Sbjct: 64   DILKAMDNLVEPNRHEALAVDARQEIDLKVGVAFTRFQTSYFQGKYGNLDSRVISYGPCQ 123

Query: 1833 TPTLGFCVQRHLQIITFKPEKFWKLHPYILHKGYELKLEWNRNRLFDLDVTEMFRNIIKE 1654
            TPTLGFCVQR+LQI TFKPEKFW L PYI+  GYEL+LEW R +LFD+DV  MF+ ++ E
Sbjct: 124  TPTLGFCVQRYLQINTFKPEKFWALRPYIIQNGYELQLEWKRQKLFDIDVAMMFQKLVTE 183

Query: 1653 DGILKVIAISEKQESKSRPAGLNTVNLLKVASSALGFGPQLAMQLAERLYTQGFISREYS 1474
            DGIL+VI +SEKQE+K RP+GLNTVNLLKVASSALG+GPQ AMQ+AERLYTQGFIS   +
Sbjct: 184  DGILEVIDVSEKQETKGRPSGLNTVNLLKVASSALGYGPQTAMQIAERLYTQGFISYPRT 243

Query: 1473 IST 1465
             ST
Sbjct: 244  EST 246


>ref|XP_012455604.1| PREDICTED: DNA topoisomerase 3-beta isoform X2 [Gossypium raimondii]
          Length = 829

 Score =  874 bits (2258), Expect(2) = 0.0
 Identities = 400/501 (79%), Positives = 452/501 (90%), Gaps = 8/501 (1%)
 Frame = -2

Query: 1484 ESTAYPPSFDFRGTLRALDNNPEWREYVQELLADGYVKPRSGNDAGDHPPITPMRSATQD 1305
            ESTAYP SFDF+GTL+ L+NNP W + VQ LLA+GY KPR+G DAGDHPPITPMR AT+D
Sbjct: 292  ESTAYPSSFDFKGTLKVLENNPSWSDCVQRLLAEGYHKPRTGTDAGDHPPITPMRPATED 351

Query: 1304 MLGHDAWKLYQYVCQHFLGTLSPDTKYSRVKIEFAVAGELFQCIGQHVTVKGFASIMPWL 1125
            +LG+DAW+LYQY+CQHF+GT+SPD KY R K+EF++ GE F CIGQ VTV+GF  IMPWL
Sbjct: 352  VLGNDAWRLYQYICQHFMGTVSPDCKYVRTKVEFSIGGEFFHCIGQRVTVQGFTYIMPWL 411

Query: 1124 AVSEKSLPQFTQGEKIEISRIEVDEGNTAPPDYLTESELISLMEKNGIGTDASIPVHINN 945
            A++EK+LPQFT+GEKIE+SR+E+ EG T+PPDYL+ESELISLMEKNGIGTDASIPVHINN
Sbjct: 412  AINEKNLPQFTKGEKIEVSRVELYEGETSPPDYLSESELISLMEKNGIGTDASIPVHINN 471

Query: 944  ICERNYVQVQAGRRLVPTALGVSLIRGYQCIDPDLCLPDIRSFIEHQITLVAKGQADHSL 765
            ICERNYVQVQAGRRLVPT LG++LIRGYQCIDPDLCLPDIRSFIEHQITLVAKGQA+H  
Sbjct: 472  ICERNYVQVQAGRRLVPTTLGITLIRGYQCIDPDLCLPDIRSFIEHQITLVAKGQANHFR 531

Query: 764  VVEHVIKQFKMKFSYFVKQIENMDALFEAEFSPLSDSGRFLSKCGKCLRYMRYISTQPSR 585
            VV+HV++QFK KF YF++QIENMDALFEA+FSPL+DSGR LSKCGKCLRYM+YIS QP R
Sbjct: 532  VVQHVLQQFKQKFCYFLQQIENMDALFEAQFSPLADSGRALSKCGKCLRYMKYISAQPQR 591

Query: 584  LYCGTCEEIYYIPQKGTIKLYKELTCPLDNFELLIFSMPGPEGKSFPLCPYCYNCPPFEG 405
            ++CGTCEE+YY+PQKGTIKLYKELTCPLDNFELLIFSMPGPEGKSFPLCPYCYN PPFEG
Sbjct: 592  MFCGTCEEVYYLPQKGTIKLYKELTCPLDNFELLIFSMPGPEGKSFPLCPYCYNSPPFEG 651

Query: 404  IDTLF--------VKSGKGAGMPCFLCPHPTCQHSMISQGVCACPECNGTLVLDPVSAPK 249
            IDTLF         K GKGAGMPCFLC HPTC+HS+++QGVCACPEC+GTLVLDPVSAPK
Sbjct: 652  IDTLFGSAKIGSTGKLGKGAGMPCFLCLHPTCRHSVVAQGVCACPECSGTLVLDPVSAPK 711

Query: 248  WRLYCNMCNCLVFLPEGAHRISTTRDHCPECDSTIIEVDFNKKTTPLKDGATLHVGCVLC 69
            WRLYCN CNCLV LPEGAHRI+TTRD C ECDSTIIEVDFNKKTTPL+DGATLH GC+LC
Sbjct: 712  WRLYCNKCNCLVLLPEGAHRIATTRDRCAECDSTIIEVDFNKKTTPLEDGATLHTGCILC 771

Query: 68   DELLHSLVVMKYGRSFSRHRG 6
            DELLHSLV +K+G+SF R  G
Sbjct: 772  DELLHSLVEVKHGKSFGRGFG 792



 Score =  395 bits (1014), Expect(2) = 0.0
 Identities = 193/244 (79%), Positives = 217/244 (88%), Gaps = 1/244 (0%)
 Frame = -1

Query: 2193 KAHICRHLNQEARGFGHLVLWLDCDREGENICFEVIECTGFHAKDGK-RVYRARFSSVTE 2017
            +AHI +HL+QEARG G+LVLWLDCDREGENICFEVIECT F   + K RVYRARFSSVTE
Sbjct: 51   RAHISKHLSQEARGCGYLVLWLDCDREGENICFEVIECTRFPMNEAKKRVYRARFSSVTE 110

Query: 2016 KDILKAMNNLVEPNKNEALAVDARQEIDLKVGVSFTRFQTSYFNGKYGNLDSRVISYGPC 1837
            KDILKAM+NLVEPN++EALAVDARQEIDLKVGV+FTRFQTSYF GKYGNLDSRVISYGPC
Sbjct: 111  KDILKAMDNLVEPNRHEALAVDARQEIDLKVGVAFTRFQTSYFQGKYGNLDSRVISYGPC 170

Query: 1836 QTPTLGFCVQRHLQIITFKPEKFWKLHPYILHKGYELKLEWNRNRLFDLDVTEMFRNIIK 1657
            QTPTLGFCVQR+LQI TFKPEKFW L PYI+  GYEL+LEW R +LFD+DV  MF+ ++ 
Sbjct: 171  QTPTLGFCVQRYLQINTFKPEKFWALRPYIIQNGYELQLEWKRQKLFDIDVAMMFQKLVT 230

Query: 1656 EDGILKVIAISEKQESKSRPAGLNTVNLLKVASSALGFGPQLAMQLAERLYTQGFISREY 1477
            EDGIL+VI +SEKQE+K RP+GLNTVNLLKVASSALG+GPQ AMQ+AERLYTQGFIS   
Sbjct: 231  EDGILEVIDVSEKQETKGRPSGLNTVNLLKVASSALGYGPQTAMQIAERLYTQGFISYPR 290

Query: 1476 SIST 1465
            + ST
Sbjct: 291  TEST 294


>ref|XP_012455603.1| PREDICTED: DNA topoisomerase 3-beta isoform X1 [Gossypium raimondii]
            gi|763805010|gb|KJB71948.1| hypothetical protein
            B456_011G150100 [Gossypium raimondii]
          Length = 872

 Score =  874 bits (2258), Expect(2) = 0.0
 Identities = 400/501 (79%), Positives = 452/501 (90%), Gaps = 8/501 (1%)
 Frame = -2

Query: 1484 ESTAYPPSFDFRGTLRALDNNPEWREYVQELLADGYVKPRSGNDAGDHPPITPMRSATQD 1305
            ESTAYP SFDF+GTL+ L+NNP W + VQ LLA+GY KPR+G DAGDHPPITPMR AT+D
Sbjct: 335  ESTAYPSSFDFKGTLKVLENNPSWSDCVQRLLAEGYHKPRTGTDAGDHPPITPMRPATED 394

Query: 1304 MLGHDAWKLYQYVCQHFLGTLSPDTKYSRVKIEFAVAGELFQCIGQHVTVKGFASIMPWL 1125
            +LG+DAW+LYQY+CQHF+GT+SPD KY R K+EF++ GE F CIGQ VTV+GF  IMPWL
Sbjct: 395  VLGNDAWRLYQYICQHFMGTVSPDCKYVRTKVEFSIGGEFFHCIGQRVTVQGFTYIMPWL 454

Query: 1124 AVSEKSLPQFTQGEKIEISRIEVDEGNTAPPDYLTESELISLMEKNGIGTDASIPVHINN 945
            A++EK+LPQFT+GEKIE+SR+E+ EG T+PPDYL+ESELISLMEKNGIGTDASIPVHINN
Sbjct: 455  AINEKNLPQFTKGEKIEVSRVELYEGETSPPDYLSESELISLMEKNGIGTDASIPVHINN 514

Query: 944  ICERNYVQVQAGRRLVPTALGVSLIRGYQCIDPDLCLPDIRSFIEHQITLVAKGQADHSL 765
            ICERNYVQVQAGRRLVPT LG++LIRGYQCIDPDLCLPDIRSFIEHQITLVAKGQA+H  
Sbjct: 515  ICERNYVQVQAGRRLVPTTLGITLIRGYQCIDPDLCLPDIRSFIEHQITLVAKGQANHFR 574

Query: 764  VVEHVIKQFKMKFSYFVKQIENMDALFEAEFSPLSDSGRFLSKCGKCLRYMRYISTQPSR 585
            VV+HV++QFK KF YF++QIENMDALFEA+FSPL+DSGR LSKCGKCLRYM+YIS QP R
Sbjct: 575  VVQHVLQQFKQKFCYFLQQIENMDALFEAQFSPLADSGRALSKCGKCLRYMKYISAQPQR 634

Query: 584  LYCGTCEEIYYIPQKGTIKLYKELTCPLDNFELLIFSMPGPEGKSFPLCPYCYNCPPFEG 405
            ++CGTCEE+YY+PQKGTIKLYKELTCPLDNFELLIFSMPGPEGKSFPLCPYCYN PPFEG
Sbjct: 635  MFCGTCEEVYYLPQKGTIKLYKELTCPLDNFELLIFSMPGPEGKSFPLCPYCYNSPPFEG 694

Query: 404  IDTLF--------VKSGKGAGMPCFLCPHPTCQHSMISQGVCACPECNGTLVLDPVSAPK 249
            IDTLF         K GKGAGMPCFLC HPTC+HS+++QGVCACPEC+GTLVLDPVSAPK
Sbjct: 695  IDTLFGSAKIGSTGKLGKGAGMPCFLCLHPTCRHSVVAQGVCACPECSGTLVLDPVSAPK 754

Query: 248  WRLYCNMCNCLVFLPEGAHRISTTRDHCPECDSTIIEVDFNKKTTPLKDGATLHVGCVLC 69
            WRLYCN CNCLV LPEGAHRI+TTRD C ECDSTIIEVDFNKKTTPL+DGATLH GC+LC
Sbjct: 755  WRLYCNKCNCLVLLPEGAHRIATTRDRCAECDSTIIEVDFNKKTTPLEDGATLHTGCILC 814

Query: 68   DELLHSLVVMKYGRSFSRHRG 6
            DELLHSLV +K+G+SF R  G
Sbjct: 815  DELLHSLVEVKHGKSFGRGFG 835



 Score =  395 bits (1014), Expect(2) = 0.0
 Identities = 193/244 (79%), Positives = 217/244 (88%), Gaps = 1/244 (0%)
 Frame = -1

Query: 2193 KAHICRHLNQEARGFGHLVLWLDCDREGENICFEVIECTGFHAKDGK-RVYRARFSSVTE 2017
            +AHI +HL+QEARG G+LVLWLDCDREGENICFEVIECT F   + K RVYRARFSSVTE
Sbjct: 94   RAHISKHLSQEARGCGYLVLWLDCDREGENICFEVIECTRFPMNEAKKRVYRARFSSVTE 153

Query: 2016 KDILKAMNNLVEPNKNEALAVDARQEIDLKVGVSFTRFQTSYFNGKYGNLDSRVISYGPC 1837
            KDILKAM+NLVEPN++EALAVDARQEIDLKVGV+FTRFQTSYF GKYGNLDSRVISYGPC
Sbjct: 154  KDILKAMDNLVEPNRHEALAVDARQEIDLKVGVAFTRFQTSYFQGKYGNLDSRVISYGPC 213

Query: 1836 QTPTLGFCVQRHLQIITFKPEKFWKLHPYILHKGYELKLEWNRNRLFDLDVTEMFRNIIK 1657
            QTPTLGFCVQR+LQI TFKPEKFW L PYI+  GYEL+LEW R +LFD+DV  MF+ ++ 
Sbjct: 214  QTPTLGFCVQRYLQINTFKPEKFWALRPYIIQNGYELQLEWKRQKLFDIDVAMMFQKLVT 273

Query: 1656 EDGILKVIAISEKQESKSRPAGLNTVNLLKVASSALGFGPQLAMQLAERLYTQGFISREY 1477
            EDGIL+VI +SEKQE+K RP+GLNTVNLLKVASSALG+GPQ AMQ+AERLYTQGFIS   
Sbjct: 274  EDGILEVIDVSEKQETKGRPSGLNTVNLLKVASSALGYGPQTAMQIAERLYTQGFISYPR 333

Query: 1476 SIST 1465
            + ST
Sbjct: 334  TEST 337


>ref|XP_007034151.1| DNA topoisomerase, type IA, core [Theobroma cacao]
            gi|508713180|gb|EOY05077.1| DNA topoisomerase, type IA,
            core [Theobroma cacao]
          Length = 868

 Score =  870 bits (2247), Expect(2) = 0.0
 Identities = 401/501 (80%), Positives = 450/501 (89%), Gaps = 8/501 (1%)
 Frame = -2

Query: 1484 ESTAYPPSFDFRGTLRALDNNPEWREYVQELLADGYVKPRSGNDAGDHPPITPMRSATQD 1305
            ESTAYP SFDF+GTL  + NN  W +YVQ LLA+GY KPRSG DAGDHPPITPM SAT+D
Sbjct: 335  ESTAYPASFDFKGTLNVIANNSLWGDYVQRLLAEGYHKPRSGTDAGDHPPITPMHSATED 394

Query: 1304 MLGHDAWKLYQYVCQHFLGTLSPDTKYSRVKIEFAVAGELFQCIGQHVTVKGFASIMPWL 1125
            +LG DAW LYQYVCQHF+GT+SPD KY R K+EF V GE F CIGQHVT +GF  IMPWL
Sbjct: 395  ILGKDAWSLYQYVCQHFIGTVSPDCKYVRRKVEFLVGGEYFHCIGQHVTAQGFTYIMPWL 454

Query: 1124 AVSEKSLPQFTQGEKIEISRIEVDEGNTAPPDYLTESELISLMEKNGIGTDASIPVHINN 945
            A++EK+LPQFT+GEKIE+S++E+ EG T+PPDYL+ESELISLME+N IGTDASIPVHINN
Sbjct: 455  AINEKNLPQFTKGEKIEVSKVELYEGETSPPDYLSESELISLMERNRIGTDASIPVHINN 514

Query: 944  ICERNYVQVQAGRRLVPTALGVSLIRGYQCIDPDLCLPDIRSFIEHQITLVAKGQADHSL 765
            ICERNYVQVQ GR+LVPTALG++LIRGYQCIDPDLCLPDIRSFIEHQITLVAKGQA+HS 
Sbjct: 515  ICERNYVQVQGGRKLVPTALGITLIRGYQCIDPDLCLPDIRSFIEHQITLVAKGQANHSH 574

Query: 764  VVEHVIKQFKMKFSYFVKQIENMDALFEAEFSPLSDSGRFLSKCGKCLRYMRYISTQPSR 585
            VV+HV++QFK KFSYFV+QIENMDALFEA+FSPL+DSGR LSKCGKCLRYM+YISTQP R
Sbjct: 575  VVQHVLQQFKQKFSYFVQQIENMDALFEAQFSPLADSGRALSKCGKCLRYMKYISTQPPR 634

Query: 584  LYCGTCEEIYYIPQKGTIKLYKELTCPLDNFELLIFSMPGPEGKSFPLCPYCYNCPPFEG 405
            L+CGTCEE+Y++PQKGTIKLYKELTCPLDNFELLIFSMPGPEGKSFPLCPYCYN PPFEG
Sbjct: 635  LFCGTCEEVYHLPQKGTIKLYKELTCPLDNFELLIFSMPGPEGKSFPLCPYCYNSPPFEG 694

Query: 404  IDTLF--------VKSGKGAGMPCFLCPHPTCQHSMISQGVCACPECNGTLVLDPVSAPK 249
            +DTLF         K GKGAGMPCFLCPHPTC+HS+++QGVCACPEC+GTLVLDPVSAPK
Sbjct: 695  MDTLFGATRIGSSGKLGKGAGMPCFLCPHPTCRHSVVAQGVCACPECSGTLVLDPVSAPK 754

Query: 248  WRLYCNMCNCLVFLPEGAHRISTTRDHCPECDSTIIEVDFNKKTTPLKDGATLHVGCVLC 69
            WRLYCN CNCLV LPEGAHRI+TTR+ C ECDSTIIEVDFNKKTTPL+DGATLH GC+LC
Sbjct: 755  WRLYCNKCNCLVLLPEGAHRIATTRERCAECDSTIIEVDFNKKTTPLEDGATLHTGCILC 814

Query: 68   DELLHSLVVMKYGRSFSRHRG 6
            DELLHS V +K+G+SFSR  G
Sbjct: 815  DELLHSFVEVKHGKSFSRGLG 835



 Score =  401 bits (1031), Expect(2) = 0.0
 Identities = 197/244 (80%), Positives = 217/244 (88%), Gaps = 1/244 (0%)
 Frame = -1

Query: 2193 KAHICRHLNQEARGFGHLVLWLDCDREGENICFEVIECTGFHAKDGK-RVYRARFSSVTE 2017
            KAHI RHL+QEARG G+LVLWLDCDREGENICFEVIECTGFH  + K RVYRARFSSVTE
Sbjct: 94   KAHISRHLSQEARGCGYLVLWLDCDREGENICFEVIECTGFHMNEAKKRVYRARFSSVTE 153

Query: 2016 KDILKAMNNLVEPNKNEALAVDARQEIDLKVGVSFTRFQTSYFNGKYGNLDSRVISYGPC 1837
            KDI KAM+NLVEPN++EALAVDARQEIDLKVGV+FTRFQT YF GKYGNLDSRVISYGPC
Sbjct: 154  KDISKAMDNLVEPNRHEALAVDARQEIDLKVGVAFTRFQTRYFQGKYGNLDSRVISYGPC 213

Query: 1836 QTPTLGFCVQRHLQIITFKPEKFWKLHPYILHKGYELKLEWNRNRLFDLDVTEMFRNIIK 1657
            QTPTLGFCVQR+LQI TFKPEKFW L PYI+  GY+L+LEW R +LFD+DV  MF+ ++ 
Sbjct: 214  QTPTLGFCVQRYLQINTFKPEKFWALRPYIIQNGYDLQLEWKRQKLFDIDVAIMFQKLVT 273

Query: 1656 EDGILKVIAISEKQESKSRPAGLNTVNLLKVASSALGFGPQLAMQLAERLYTQGFISREY 1477
            EDGIL+VI +SEKQESK RP+GLNTVNLLKVASSALGFGPQ AMQLAERLYTQGFIS   
Sbjct: 274  EDGILEVIDVSEKQESKGRPSGLNTVNLLKVASSALGFGPQTAMQLAERLYTQGFISYPR 333

Query: 1476 SIST 1465
            + ST
Sbjct: 334  TEST 337