BLASTX 2.2.25 [Feb-01-2011]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= Forsythia23_contig00007470
         (2249 letters)

Database: ./nr 
           69,698,275 sequences; 24,982,196,650 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

ref|XP_011074562.1| PREDICTED: putative bifunctional dihydrofola...   894   0.0  
ref|XP_011074564.1| PREDICTED: putative bifunctional dihydrofola...   886   0.0  
ref|XP_012843023.1| PREDICTED: bifunctional dihydrofolate reduct...   861   0.0  
ref|XP_012843024.1| PREDICTED: bifunctional dihydrofolate reduct...   842   0.0  
ref|XP_010254749.1| PREDICTED: putative bifunctional dihydrofola...   842   0.0  
ref|XP_010254750.1| PREDICTED: putative bifunctional dihydrofola...   838   0.0  
ref|XP_010664716.1| PREDICTED: putative bifunctional dihydrofola...   833   0.0  
ref|XP_010254751.1| PREDICTED: putative bifunctional dihydrofola...   830   0.0  
ref|XP_011037491.1| PREDICTED: bifunctional dihydrofolate reduct...   826   0.0  
ref|XP_006384511.1| hypothetical protein POPTR_0004s16470g [Popu...   825   0.0  
ref|XP_008377275.1| PREDICTED: bifunctional dihydrofolate reduct...   824   0.0  
emb|CDP07483.1| unnamed protein product [Coffea canephora]            823   0.0  
ref|XP_012480346.1| PREDICTED: bifunctional dihydrofolate reduct...   823   0.0  
ref|XP_010664719.1| PREDICTED: putative bifunctional dihydrofola...   823   0.0  
gb|KDO47901.1| hypothetical protein CISIN_1g009747mg [Citrus sin...   823   0.0  
ref|XP_012067239.1| PREDICTED: bifunctional dihydrofolate reduct...   822   0.0  
ref|XP_009378649.1| PREDICTED: bifunctional dihydrofolate reduct...   822   0.0  
ref|XP_009378647.1| PREDICTED: bifunctional dihydrofolate reduct...   822   0.0  
ref|XP_008236926.1| PREDICTED: bifunctional dihydrofolate reduct...   822   0.0  
ref|XP_010664720.1| PREDICTED: putative bifunctional dihydrofola...   821   0.0  

>ref|XP_011074562.1| PREDICTED: putative bifunctional dihydrofolate reductase-thymidylate
            synthase isoform X1 [Sesamum indicum]
            gi|747056600|ref|XP_011074563.1| PREDICTED: putative
            bifunctional dihydrofolate reductase-thymidylate synthase
            isoform X1 [Sesamum indicum]
          Length = 584

 Score =  894 bits (2310), Expect = 0.0
 Identities = 435/575 (75%), Positives = 483/575 (84%)
 Frame = -1

Query: 2069 LVQAKGKGTLGTCQINFFSSASVTPFTRSFRVPNIFSKQRSYCEYSVMSENSIACHSNGN 1890
            +  +  K TLG+   N  S+   +   ++      F+ QR    Y VM  ++I C SNGN
Sbjct: 11   IAMSNRKVTLGSFGSNILSAWG-SSLPQAPETLKAFNTQRFCRRYLVMGGDAIECFSNGN 69

Query: 1889 ADTQPPLHRTYQVVVAATRDMGIGKDGKFPWKLPSDLKFFKEITMTTSDPEKKNAVIMGR 1710
              T+P   RTYQVVVAAT DMGIGKDGK PW+LP DLKFFKEIT TTSDP KKNAV+MGR
Sbjct: 70   TTTEPISQRTYQVVVAATPDMGIGKDGKLPWRLPGDLKFFKEITATTSDPNKKNAVMMGR 129

Query: 1709 KTWESIPPQFQPLPGRLNVILTRSGSFDMATAENVITCGSIPSALKLLAEPPYNILIEKV 1530
            +TWESIPPQF+PLPGRLNV+LTRS S D+A AENVI+C S+ SALKLLAEPPY++ +EKV
Sbjct: 130  RTWESIPPQFRPLPGRLNVVLTRSASSDVAAAENVISCRSMSSALKLLAEPPYSLSVEKV 189

Query: 1529 FMIGGGQILGEALNAPECDAIHMTEIESHMECDTFIPPVDLSVYQPWYSSTPEVENNIRY 1350
            F+IGGGQIL EALNA ECDAIH+TEI++ +ECDTFIPP+D+S+YQPWYSSTP  EN I+Y
Sbjct: 190  FLIGGGQILREALNAAECDAIHITEIKTSVECDTFIPPIDMSIYQPWYSSTPVEENGIQY 249

Query: 1349 CFVTFVRLKTSIGGPTNSSPEVRCNGSILDFKKFKVLNFTFLPRMIFEKHEEFLYLKLVQ 1170
            CF T+VRL+TS  GP NS  E+ CNGS    K+ K+ +FT+LP+ IFEKHEEF YL+LVQ
Sbjct: 250  CFATYVRLRTSTSGPVNSGHELSCNGSTSRSKRPKLSDFTYLPKFIFEKHEEFQYLRLVQ 309

Query: 1169 DIISNGNDKGDRTGTGTLSKFGCQMRFNLRKSFPLLTTKRVFWRGVVEELLWFISGSPNA 990
            DIISNGN K DRTGTGTLS FGCQM FNLRKSFPLLTTKRVFWRGVVEELLWFISGS NA
Sbjct: 310  DIISNGNSKDDRTGTGTLSNFGCQMHFNLRKSFPLLTTKRVFWRGVVEELLWFISGSTNA 369

Query: 989  KVLQEKGIHIWDGNASREYLDSIGLADREEGDLGPVYGFQWRHFGARYTNMHADYTGQGF 810
            K+LQEKGIHIWDGNASRE+LDSIGL DREEGDLGP+YGFQWRHFGARYTNMHADYTGQGF
Sbjct: 370  KILQEKGIHIWDGNASREFLDSIGLTDREEGDLGPIYGFQWRHFGARYTNMHADYTGQGF 429

Query: 809  DQLLDAIDKIKNKPDDRRIILSAWNPSDLKLMALPPCHMFAQFYVANGELSCQMYQRSAD 630
            DQLLD IDKIKNKPDDRRIILSAWNPSDLKLMALPPCHMFAQFYVANGELSCQMYQRSAD
Sbjct: 430  DQLLDVIDKIKNKPDDRRIILSAWNPSDLKLMALPPCHMFAQFYVANGELSCQMYQRSAD 489

Query: 629  MGLGVPFNIASYALLTCMIAHVCGLVPGDLIHVIGDAHVYKTHISPLQEQLXXXXXXXXX 450
            MGLGVPFNIASYALLTCMIAHVCGL+PG+ +HVIGDAHVYKTHISPLQEQL         
Sbjct: 490  MGLGVPFNIASYALLTCMIAHVCGLIPGEFVHVIGDAHVYKTHISPLQEQLKKLPRPFPI 549

Query: 449  XXXXPQTKDIDSFVAADFELINYEPHQKLEMKLAV 345
                P+ KDIDSFVAADFEL NYEPHQKLEMK+AV
Sbjct: 550  LKINPEKKDIDSFVAADFELRNYEPHQKLEMKMAV 584


>ref|XP_011074564.1| PREDICTED: putative bifunctional dihydrofolate reductase-thymidylate
            synthase isoform X2 [Sesamum indicum]
            gi|747056604|ref|XP_011074565.1| PREDICTED: putative
            bifunctional dihydrofolate reductase-thymidylate synthase
            isoform X2 [Sesamum indicum]
            gi|747056606|ref|XP_011074566.1| PREDICTED: putative
            bifunctional dihydrofolate reductase-thymidylate synthase
            isoform X2 [Sesamum indicum]
          Length = 528

 Score =  886 bits (2290), Expect = 0.0
 Identities = 424/528 (80%), Positives = 464/528 (87%)
 Frame = -1

Query: 1928 MSENSIACHSNGNADTQPPLHRTYQVVVAATRDMGIGKDGKFPWKLPSDLKFFKEITMTT 1749
            M  ++I C SNGN  T+P   RTYQVVVAAT DMGIGKDGK PW+LP DLKFFKEIT TT
Sbjct: 1    MGGDAIECFSNGNTTTEPISQRTYQVVVAATPDMGIGKDGKLPWRLPGDLKFFKEITATT 60

Query: 1748 SDPEKKNAVIMGRKTWESIPPQFQPLPGRLNVILTRSGSFDMATAENVITCGSIPSALKL 1569
            SDP KKNAV+MGR+TWESIPPQF+PLPGRLNV+LTRS S D+A AENVI+C S+ SALKL
Sbjct: 61   SDPNKKNAVMMGRRTWESIPPQFRPLPGRLNVVLTRSASSDVAAAENVISCRSMSSALKL 120

Query: 1568 LAEPPYNILIEKVFMIGGGQILGEALNAPECDAIHMTEIESHMECDTFIPPVDLSVYQPW 1389
            LAEPPY++ +EKVF+IGGGQIL EALNA ECDAIH+TEI++ +ECDTFIPP+D+S+YQPW
Sbjct: 121  LAEPPYSLSVEKVFLIGGGQILREALNAAECDAIHITEIKTSVECDTFIPPIDMSIYQPW 180

Query: 1388 YSSTPEVENNIRYCFVTFVRLKTSIGGPTNSSPEVRCNGSILDFKKFKVLNFTFLPRMIF 1209
            YSSTP  EN I+YCF T+VRL+TS  GP NS  E+ CNGS    K+ K+ +FT+LP+ IF
Sbjct: 181  YSSTPVEENGIQYCFATYVRLRTSTSGPVNSGHELSCNGSTSRSKRPKLSDFTYLPKFIF 240

Query: 1208 EKHEEFLYLKLVQDIISNGNDKGDRTGTGTLSKFGCQMRFNLRKSFPLLTTKRVFWRGVV 1029
            EKHEEF YL+LVQDIISNGN K DRTGTGTLS FGCQM FNLRKSFPLLTTKRVFWRGVV
Sbjct: 241  EKHEEFQYLRLVQDIISNGNSKDDRTGTGTLSNFGCQMHFNLRKSFPLLTTKRVFWRGVV 300

Query: 1028 EELLWFISGSPNAKVLQEKGIHIWDGNASREYLDSIGLADREEGDLGPVYGFQWRHFGAR 849
            EELLWFISGS NAK+LQEKGIHIWDGNASRE+LDSIGL DREEGDLGP+YGFQWRHFGAR
Sbjct: 301  EELLWFISGSTNAKILQEKGIHIWDGNASREFLDSIGLTDREEGDLGPIYGFQWRHFGAR 360

Query: 848  YTNMHADYTGQGFDQLLDAIDKIKNKPDDRRIILSAWNPSDLKLMALPPCHMFAQFYVAN 669
            YTNMHADYTGQGFDQLLD IDKIKNKPDDRRIILSAWNPSDLKLMALPPCHMFAQFYVAN
Sbjct: 361  YTNMHADYTGQGFDQLLDVIDKIKNKPDDRRIILSAWNPSDLKLMALPPCHMFAQFYVAN 420

Query: 668  GELSCQMYQRSADMGLGVPFNIASYALLTCMIAHVCGLVPGDLIHVIGDAHVYKTHISPL 489
            GELSCQMYQRSADMGLGVPFNIASYALLTCMIAHVCGL+PG+ +HVIGDAHVYKTHISPL
Sbjct: 421  GELSCQMYQRSADMGLGVPFNIASYALLTCMIAHVCGLIPGEFVHVIGDAHVYKTHISPL 480

Query: 488  QEQLXXXXXXXXXXXXXPQTKDIDSFVAADFELINYEPHQKLEMKLAV 345
            QEQL             P+ KDIDSFVAADFEL NYEPHQKLEMK+AV
Sbjct: 481  QEQLKKLPRPFPILKINPEKKDIDSFVAADFELRNYEPHQKLEMKMAV 528


>ref|XP_012843023.1| PREDICTED: bifunctional dihydrofolate reductase-thymidylate synthase
            1-like isoform X1 [Erythranthe guttatus]
          Length = 584

 Score =  861 bits (2225), Expect = 0.0
 Identities = 425/581 (73%), Positives = 477/581 (82%)
 Frame = -1

Query: 2087 NANFDCLVQAKGKGTLGTCQINFFSSASVTPFTRSFRVPNIFSKQRSYCEYSVMSENSIA 1908
            N N   L+ A G  TLG+ + + F ++S + F  SF+    F+ QR    Y  M+ +SI 
Sbjct: 15   NLNLAALLMA-GTVTLGSFRNSIFRASSQSSFILSFKSLKPFAAQRFCRRYLSMASDSIQ 73

Query: 1907 CHSNGNADTQPPLHRTYQVVVAATRDMGIGKDGKFPWKLPSDLKFFKEITMTTSDPEKKN 1728
            C SNGN + Q    R+YQVVVAAT DMGIGK+GK PW+LP DLKFFKEIT TTSDP KKN
Sbjct: 74   CVSNGNDNAQSIPERSYQVVVAATPDMGIGKEGKLPWRLPGDLKFFKEITATTSDPNKKN 133

Query: 1727 AVIMGRKTWESIPPQFQPLPGRLNVILTRSGSFDMATAENVITCGSIPSALKLLAEPPYN 1548
            AV+MGRKTWESIPPQF+PLPGRLNV+LTRSGS D  + E+V+ CGS+ SALKLLA PPY+
Sbjct: 134  AVLMGRKTWESIPPQFRPLPGRLNVVLTRSGSSDSNSDESVVFCGSMSSALKLLAGPPYS 193

Query: 1547 ILIEKVFMIGGGQILGEALNAPECDAIHMTEIESHMECDTFIPPVDLSVYQPWYSSTPEV 1368
              IEKVF+IGGGQIL EA NA +CDAIH+TE++S +ECDTFIPP+D+SVYQPWYSS+   
Sbjct: 194  FNIEKVFLIGGGQILREAFNALQCDAIHITELKSFIECDTFIPPIDMSVYQPWYSSSVIE 253

Query: 1367 ENNIRYCFVTFVRLKTSIGGPTNSSPEVRCNGSILDFKKFKVLNFTFLPRMIFEKHEEFL 1188
            EN I+YCF T+VRLK SI GP ++S   R           K+ +FTFLP+ IF+KHEEFL
Sbjct: 254  ENGIKYCFATYVRLKNSIKGPVSTSHSNR----------LKLSDFTFLPKHIFDKHEEFL 303

Query: 1187 YLKLVQDIISNGNDKGDRTGTGTLSKFGCQMRFNLRKSFPLLTTKRVFWRGVVEELLWFI 1008
            YL+LVQDIISNGN+K DRTGTGTLSKFGCQ+RFNLRKSFPLLTTKRVFWRGVVEELLWFI
Sbjct: 304  YLRLVQDIISNGNNKDDRTGTGTLSKFGCQIRFNLRKSFPLLTTKRVFWRGVVEELLWFI 363

Query: 1007 SGSPNAKVLQEKGIHIWDGNASREYLDSIGLADREEGDLGPVYGFQWRHFGARYTNMHAD 828
            SGS NAK+LQEKGIHIWDGNASR++LDSIGL +REEGDLGPVYGFQWRHFGARYTNMH D
Sbjct: 364  SGSTNAKILQEKGIHIWDGNASRDFLDSIGLTEREEGDLGPVYGFQWRHFGARYTNMHDD 423

Query: 827  YTGQGFDQLLDAIDKIKNKPDDRRIILSAWNPSDLKLMALPPCHMFAQFYVANGELSCQM 648
            YTGQG DQL+D IDKIKNKPDDRRIILSAWNPSDLKLMALPPCHM AQFYVANGELSCQM
Sbjct: 424  YTGQGIDQLMDVIDKIKNKPDDRRIILSAWNPSDLKLMALPPCHMSAQFYVANGELSCQM 483

Query: 647  YQRSADMGLGVPFNIASYALLTCMIAHVCGLVPGDLIHVIGDAHVYKTHISPLQEQLXXX 468
            YQRSADMGLGVPFNIASYALLTCMIAHVCGLVPGD IHV GDAHVYKTH+ PLQEQL   
Sbjct: 484  YQRSADMGLGVPFNIASYALLTCMIAHVCGLVPGDFIHVFGDAHVYKTHVGPLQEQLKKL 543

Query: 467  XXXXXXXXXXPQTKDIDSFVAADFELINYEPHQKLEMKLAV 345
                       + KDIDSFVA DFEL+NYEPHQKLEMK+AV
Sbjct: 544  PRPFPILRINTEKKDIDSFVAGDFELVNYEPHQKLEMKMAV 584


>ref|XP_012843024.1| PREDICTED: bifunctional dihydrofolate reductase-thymidylate synthase
            1-like isoform X2 [Erythranthe guttatus]
            gi|848885554|ref|XP_012843025.1| PREDICTED: bifunctional
            dihydrofolate reductase-thymidylate synthase 1-like
            isoform X2 [Erythranthe guttatus]
            gi|604322384|gb|EYU32770.1| hypothetical protein
            MIMGU_mgv1a004601mg [Erythranthe guttata]
          Length = 518

 Score =  842 bits (2176), Expect = 0.0
 Identities = 408/528 (77%), Positives = 451/528 (85%)
 Frame = -1

Query: 1928 MSENSIACHSNGNADTQPPLHRTYQVVVAATRDMGIGKDGKFPWKLPSDLKFFKEITMTT 1749
            M+ +SI C SNGN + Q    R+YQVVVAAT DMGIGK+GK PW+LP DLKFFKEIT TT
Sbjct: 1    MASDSIQCVSNGNDNAQSIPERSYQVVVAATPDMGIGKEGKLPWRLPGDLKFFKEITATT 60

Query: 1748 SDPEKKNAVIMGRKTWESIPPQFQPLPGRLNVILTRSGSFDMATAENVITCGSIPSALKL 1569
            SDP KKNAV+MGRKTWESIPPQF+PLPGRLNV+LTRSGS D  + E+V+ CGS+ SALKL
Sbjct: 61   SDPNKKNAVLMGRKTWESIPPQFRPLPGRLNVVLTRSGSSDSNSDESVVFCGSMSSALKL 120

Query: 1568 LAEPPYNILIEKVFMIGGGQILGEALNAPECDAIHMTEIESHMECDTFIPPVDLSVYQPW 1389
            LA PPY+  IEKVF+IGGGQIL EA NA +CDAIH+TE++S +ECDTFIPP+D+SVYQPW
Sbjct: 121  LAGPPYSFNIEKVFLIGGGQILREAFNALQCDAIHITELKSFIECDTFIPPIDMSVYQPW 180

Query: 1388 YSSTPEVENNIRYCFVTFVRLKTSIGGPTNSSPEVRCNGSILDFKKFKVLNFTFLPRMIF 1209
            YSS+   EN I+YCF T+VRLK SI GP ++S   R           K+ +FTFLP+ IF
Sbjct: 181  YSSSVIEENGIKYCFATYVRLKNSIKGPVSTSHSNR----------LKLSDFTFLPKHIF 230

Query: 1208 EKHEEFLYLKLVQDIISNGNDKGDRTGTGTLSKFGCQMRFNLRKSFPLLTTKRVFWRGVV 1029
            +KHEEFLYL+LVQDIISNGN+K DRTGTGTLSKFGCQ+RFNLRKSFPLLTTKRVFWRGVV
Sbjct: 231  DKHEEFLYLRLVQDIISNGNNKDDRTGTGTLSKFGCQIRFNLRKSFPLLTTKRVFWRGVV 290

Query: 1028 EELLWFISGSPNAKVLQEKGIHIWDGNASREYLDSIGLADREEGDLGPVYGFQWRHFGAR 849
            EELLWFISGS NAK+LQEKGIHIWDGNASR++LDSIGL +REEGDLGPVYGFQWRHFGAR
Sbjct: 291  EELLWFISGSTNAKILQEKGIHIWDGNASRDFLDSIGLTEREEGDLGPVYGFQWRHFGAR 350

Query: 848  YTNMHADYTGQGFDQLLDAIDKIKNKPDDRRIILSAWNPSDLKLMALPPCHMFAQFYVAN 669
            YTNMH DYTGQG DQL+D IDKIKNKPDDRRIILSAWNPSDLKLMALPPCHM AQFYVAN
Sbjct: 351  YTNMHDDYTGQGIDQLMDVIDKIKNKPDDRRIILSAWNPSDLKLMALPPCHMSAQFYVAN 410

Query: 668  GELSCQMYQRSADMGLGVPFNIASYALLTCMIAHVCGLVPGDLIHVIGDAHVYKTHISPL 489
            GELSCQMYQRSADMGLGVPFNIASYALLTCMIAHVCGLVPGD IHV GDAHVYKTH+ PL
Sbjct: 411  GELSCQMYQRSADMGLGVPFNIASYALLTCMIAHVCGLVPGDFIHVFGDAHVYKTHVGPL 470

Query: 488  QEQLXXXXXXXXXXXXXPQTKDIDSFVAADFELINYEPHQKLEMKLAV 345
            QEQL              + KDIDSFVA DFEL+NYEPHQKLEMK+AV
Sbjct: 471  QEQLKKLPRPFPILRINTEKKDIDSFVAGDFELVNYEPHQKLEMKMAV 518


>ref|XP_010254749.1| PREDICTED: putative bifunctional dihydrofolate reductase-thymidylate
            synthase isoform X1 [Nelumbo nucifera]
          Length = 578

 Score =  842 bits (2174), Expect = 0.0
 Identities = 415/580 (71%), Positives = 474/580 (81%), Gaps = 17/580 (2%)
 Frame = -1

Query: 2033 CQIN--FFSSASVTPFTRSFRVPNIFSKQ-----------RSYCEYSVMSENSIACHSNG 1893
            C+++  F +S +++ F RS  V ++ S Q           RS  ++SVM+  +I    NG
Sbjct: 4    CKVSPTFSTSCALSRFRRSSFVSDLSSSQLFGALYSIANYRSCLKFSVMAGETIMNVPNG 63

Query: 1892 NADTQPPLHRTYQVVVAATRDMGIGKDGKFPWKLPSDLKFFKEITMTTSDPEKKNAVIMG 1713
            NA  QP   RT+QVVVAAT+ MGIGKDGK PW+LPSDLKFF+E+TM TSDP KKNAVIMG
Sbjct: 64   NASIQPDPKRTFQVVVAATKSMGIGKDGKLPWRLPSDLKFFREVTMGTSDPAKKNAVIMG 123

Query: 1712 RKTWESIPPQFQPLPGRLNVILTRSGSFDMATAENVITCGSIPSALKLLAEPPYNILIEK 1533
            RKTWE IPP+ +PLPGRLNV+LTRSGSFD+ATAENV+ CGS+ SAL+LLA  PY + IEK
Sbjct: 124  RKTWEGIPPEHRPLPGRLNVVLTRSGSFDIATAENVVICGSMSSALELLASSPYCLSIEK 183

Query: 1532 VFMIGGGQILGEALNAPECDAIHMTEIESHMECDTFIPPVDLSVYQPWYSSTPEVENNIR 1353
            VF+IGGGQIL E+LNAPECDAIH+TEIE+  ECDTFIPP++LSV+QPWYSS P +ENNIR
Sbjct: 184  VFVIGGGQILRESLNAPECDAIHITEIETSFECDTFIPPIELSVFQPWYSSFPLIENNIR 243

Query: 1352 YCFVTFVRLKTSIGGPTNSSPEVRCNGSILDFK----KFKVLNFTFLPRMIFEKHEEFLY 1185
              FVT+VR++ S             NG + D      KF++  F+FLP+MIFE+HEE++Y
Sbjct: 244  CSFVTYVRVRRSAAEYLYQD-----NGGMFDGNSNNTKFEIEKFSFLPKMIFERHEEYMY 298

Query: 1184 LKLVQDIISNGNDKGDRTGTGTLSKFGCQMRFNLRKSFPLLTTKRVFWRGVVEELLWFIS 1005
            L+LV+DIISNGN K DRTGTGTLSKFGCQM FNLRKSFPLLTTK+VFWRGVVEELLWFIS
Sbjct: 299  LRLVEDIISNGNQKDDRTGTGTLSKFGCQMHFNLRKSFPLLTTKKVFWRGVVEELLWFIS 358

Query: 1004 GSPNAKVLQEKGIHIWDGNASREYLDSIGLADREEGDLGPVYGFQWRHFGARYTNMHADY 825
            GS NAKVLQEKGIHIWDGNASR+YLDSIGL DREEGDLGP+YGFQWRH GARYTNMHADY
Sbjct: 359  GSTNAKVLQEKGIHIWDGNASRDYLDSIGLTDREEGDLGPIYGFQWRHHGARYTNMHADY 418

Query: 824  TGQGFDQLLDAIDKIKNKPDDRRIILSAWNPSDLKLMALPPCHMFAQFYVANGELSCQMY 645
            +GQGFDQLLD IDKIKNKPDDRRIILSAWNPSDLKLMALPPCHMFAQFYV NGELSCQMY
Sbjct: 419  SGQGFDQLLDVIDKIKNKPDDRRIILSAWNPSDLKLMALPPCHMFAQFYVVNGELSCQMY 478

Query: 644  QRSADMGLGVPFNIASYALLTCMIAHVCGLVPGDLIHVIGDAHVYKTHISPLQEQLXXXX 465
            QRSADMGLGVPFNIASYALLTCMIAHVC L+PGD IHVIGDAHVY+TH+ PLQEQL    
Sbjct: 479  QRSADMGLGVPFNIASYALLTCMIAHVCDLIPGDFIHVIGDAHVYRTHVRPLQEQLQKLP 538

Query: 464  XXXXXXXXXPQTKDIDSFVAADFELINYEPHQKLEMKLAV 345
                     P  KDIDSFVA DF+L+ Y+PHQK+EMK+AV
Sbjct: 539  KPFPILKINPHKKDIDSFVATDFKLVGYDPHQKIEMKMAV 578


>ref|XP_010254750.1| PREDICTED: putative bifunctional dihydrofolate reductase-thymidylate
            synthase isoform X2 [Nelumbo nucifera]
          Length = 569

 Score =  838 bits (2164), Expect = 0.0
 Identities = 412/569 (72%), Positives = 467/569 (82%), Gaps = 15/569 (2%)
 Frame = -1

Query: 2006 SVTPFTRSFRVPNIFSKQ-----------RSYCEYSVMSENSIACHSNGNADTQPPLHRT 1860
            +++ F RS  V ++ S Q           RS  ++SVM+  +I    NGNA  QP   RT
Sbjct: 6    ALSRFRRSSFVSDLSSSQLFGALYSIANYRSCLKFSVMAGETIMNVPNGNASIQPDPKRT 65

Query: 1859 YQVVVAATRDMGIGKDGKFPWKLPSDLKFFKEITMTTSDPEKKNAVIMGRKTWESIPPQF 1680
            +QVVVAAT+ MGIGKDGK PW+LPSDLKFF+E+TM TSDP KKNAVIMGRKTWE IPP+ 
Sbjct: 66   FQVVVAATKSMGIGKDGKLPWRLPSDLKFFREVTMGTSDPAKKNAVIMGRKTWEGIPPEH 125

Query: 1679 QPLPGRLNVILTRSGSFDMATAENVITCGSIPSALKLLAEPPYNILIEKVFMIGGGQILG 1500
            +PLPGRLNV+LTRSGSFD+ATAENV+ CGS+ SAL+LLA  PY + IEKVF+IGGGQIL 
Sbjct: 126  RPLPGRLNVVLTRSGSFDIATAENVVICGSMSSALELLASSPYCLSIEKVFVIGGGQILR 185

Query: 1499 EALNAPECDAIHMTEIESHMECDTFIPPVDLSVYQPWYSSTPEVENNIRYCFVTFVRLKT 1320
            E+LNAPECDAIH+TEIE+  ECDTFIPP++LSV+QPWYSS P +ENNIR  FVT+VR++ 
Sbjct: 186  ESLNAPECDAIHITEIETSFECDTFIPPIELSVFQPWYSSFPLIENNIRCSFVTYVRVRR 245

Query: 1319 SIGGPTNSSPEVRCNGSILDFK----KFKVLNFTFLPRMIFEKHEEFLYLKLVQDIISNG 1152
            S             NG + D      KF++  F+FLP+MIFE+HEE++YL+LV+DIISNG
Sbjct: 246  SAAEYLYQD-----NGGMFDGNSNNTKFEIEKFSFLPKMIFERHEEYMYLRLVEDIISNG 300

Query: 1151 NDKGDRTGTGTLSKFGCQMRFNLRKSFPLLTTKRVFWRGVVEELLWFISGSPNAKVLQEK 972
            N K DRTGTGTLSKFGCQM FNLRKSFPLLTTK+VFWRGVVEELLWFISGS NAKVLQEK
Sbjct: 301  NQKDDRTGTGTLSKFGCQMHFNLRKSFPLLTTKKVFWRGVVEELLWFISGSTNAKVLQEK 360

Query: 971  GIHIWDGNASREYLDSIGLADREEGDLGPVYGFQWRHFGARYTNMHADYTGQGFDQLLDA 792
            GIHIWDGNASR+YLDSIGL DREEGDLGP+YGFQWRH GARYTNMHADY+GQGFDQLLD 
Sbjct: 361  GIHIWDGNASRDYLDSIGLTDREEGDLGPIYGFQWRHHGARYTNMHADYSGQGFDQLLDV 420

Query: 791  IDKIKNKPDDRRIILSAWNPSDLKLMALPPCHMFAQFYVANGELSCQMYQRSADMGLGVP 612
            IDKIKNKPDDRRIILSAWNPSDLKLMALPPCHMFAQFYV NGELSCQMYQRSADMGLGVP
Sbjct: 421  IDKIKNKPDDRRIILSAWNPSDLKLMALPPCHMFAQFYVVNGELSCQMYQRSADMGLGVP 480

Query: 611  FNIASYALLTCMIAHVCGLVPGDLIHVIGDAHVYKTHISPLQEQLXXXXXXXXXXXXXPQ 432
            FNIASYALLTCMIAHVC L+PGD IHVIGDAHVY+TH+ PLQEQL             P 
Sbjct: 481  FNIASYALLTCMIAHVCDLIPGDFIHVIGDAHVYRTHVRPLQEQLQKLPKPFPILKINPH 540

Query: 431  TKDIDSFVAADFELINYEPHQKLEMKLAV 345
             KDIDSFVA DF+L+ Y+PHQK+EMK+AV
Sbjct: 541  KKDIDSFVATDFKLVGYDPHQKIEMKMAV 569


>ref|XP_010664716.1| PREDICTED: putative bifunctional dihydrofolate reductase-thymidylate
            synthase isoform X1 [Vitis vinifera]
            gi|731429640|ref|XP_010664717.1| PREDICTED: putative
            bifunctional dihydrofolate reductase-thymidylate synthase
            isoform X1 [Vitis vinifera]
            gi|731429642|ref|XP_010664718.1| PREDICTED: putative
            bifunctional dihydrofolate reductase-thymidylate synthase
            isoform X1 [Vitis vinifera]
          Length = 570

 Score =  833 bits (2152), Expect = 0.0
 Identities = 406/559 (72%), Positives = 462/559 (82%)
 Frame = -1

Query: 2021 FFSSASVTPFTRSFRVPNIFSKQRSYCEYSVMSENSIACHSNGNADTQPPLHRTYQVVVA 1842
            F    S +  +R F V N+ +K+R    YSV+S +S   + NG+A   P   RTYQVVVA
Sbjct: 13   FARPGSASALSRLFTVLNVIAKRRVQTSYSVLSGDSAMSYPNGDARVHPVPQRTYQVVVA 72

Query: 1841 ATRDMGIGKDGKFPWKLPSDLKFFKEITMTTSDPEKKNAVIMGRKTWESIPPQFQPLPGR 1662
            AT  MGIGKDGK PW LPSDLKFFKE+TMTTSDP KKNAV+MGRKTWESIP  ++PLPGR
Sbjct: 73   ATHKMGIGKDGKLPWNLPSDLKFFKELTMTTSDPGKKNAVVMGRKTWESIPLNYRPLPGR 132

Query: 1661 LNVILTRSGSFDMATAENVITCGSIPSALKLLAEPPYNILIEKVFMIGGGQILGEALNAP 1482
            LNV+LTRSGSFD AT ENV+ CGS+PSALKLLAE PY + I+KVF+IGGGQIL EALNAP
Sbjct: 133  LNVVLTRSGSFDNATVENVVICGSMPSALKLLAESPYCLSIDKVFVIGGGQILREALNAP 192

Query: 1481 ECDAIHMTEIESHMECDTFIPPVDLSVYQPWYSSTPEVENNIRYCFVTFVRLKTSIGGPT 1302
             CDAIH+T+IE+ +ECDTFIP +D SV+ PWYSS P +ENNI Y FVT+VR+++S     
Sbjct: 193  GCDAIHITKIETSIECDTFIPTIDTSVFHPWYSSVPLLENNILYSFVTYVRVRSSALESF 252

Query: 1301 NSSPEVRCNGSILDFKKFKVLNFTFLPRMIFEKHEEFLYLKLVQDIISNGNDKGDRTGTG 1122
              S  V  NG  +   K K+  FTFLP+MIFE+H+EF+YL+ +++IIS+G  K D+TGTG
Sbjct: 253  ALSSGVNFNGGSVP-NKLKIQGFTFLPKMIFERHDEFMYLRQLKEIISSGAHKADKTGTG 311

Query: 1121 TLSKFGCQMRFNLRKSFPLLTTKRVFWRGVVEELLWFISGSPNAKVLQEKGIHIWDGNAS 942
            T+SKFGCQMRFNLR SFPLLTTKRVFWRGVVEELLWFISGS NAKVLQ+K IHIWDGNAS
Sbjct: 312  TVSKFGCQMRFNLRLSFPLLTTKRVFWRGVVEELLWFISGSTNAKVLQKKDIHIWDGNAS 371

Query: 941  REYLDSIGLADREEGDLGPVYGFQWRHFGARYTNMHADYTGQGFDQLLDAIDKIKNKPDD 762
            REYLDSIGL DREEGDLGP+YGFQWRHFGARYTNMHADY G+GFDQLLD IDKIKNKPDD
Sbjct: 372  REYLDSIGLTDREEGDLGPIYGFQWRHFGARYTNMHADYMGKGFDQLLDVIDKIKNKPDD 431

Query: 761  RRIILSAWNPSDLKLMALPPCHMFAQFYVANGELSCQMYQRSADMGLGVPFNIASYALLT 582
            RRIILS+WNPSDLKLMALPPCHMFAQFYVANGELSCQMYQRSADMGLGVPFNIASYALLT
Sbjct: 432  RRIILSSWNPSDLKLMALPPCHMFAQFYVANGELSCQMYQRSADMGLGVPFNIASYALLT 491

Query: 581  CMIAHVCGLVPGDLIHVIGDAHVYKTHISPLQEQLXXXXXXXXXXXXXPQTKDIDSFVAA 402
            CMIAHVCG++PGD I +IGDAH+YKTHI PL+EQL             PQ KDI+SFVAA
Sbjct: 492  CMIAHVCGILPGDFILIIGDAHIYKTHIRPLEEQLQKLPKPFPILKINPQKKDIESFVAA 551

Query: 401  DFELINYEPHQKLEMKLAV 345
            DFELI Y PHQK+EMK++V
Sbjct: 552  DFELIGYNPHQKIEMKMSV 570


>ref|XP_010254751.1| PREDICTED: putative bifunctional dihydrofolate reductase-thymidylate
            synthase isoform X3 [Nelumbo nucifera]
            gi|719996210|ref|XP_010254752.1| PREDICTED: putative
            bifunctional dihydrofolate reductase-thymidylate synthase
            isoform X3 [Nelumbo nucifera]
          Length = 527

 Score =  830 bits (2145), Expect = 0.0
 Identities = 402/532 (75%), Positives = 450/532 (84%), Gaps = 4/532 (0%)
 Frame = -1

Query: 1928 MSENSIACHSNGNADTQPPLHRTYQVVVAATRDMGIGKDGKFPWKLPSDLKFFKEITMTT 1749
            M+  +I    NGNA  QP   RT+QVVVAAT+ MGIGKDGK PW+LPSDLKFF+E+TM T
Sbjct: 1    MAGETIMNVPNGNASIQPDPKRTFQVVVAATKSMGIGKDGKLPWRLPSDLKFFREVTMGT 60

Query: 1748 SDPEKKNAVIMGRKTWESIPPQFQPLPGRLNVILTRSGSFDMATAENVITCGSIPSALKL 1569
            SDP KKNAVIMGRKTWE IPP+ +PLPGRLNV+LTRSGSFD+ATAENV+ CGS+ SAL+L
Sbjct: 61   SDPAKKNAVIMGRKTWEGIPPEHRPLPGRLNVVLTRSGSFDIATAENVVICGSMSSALEL 120

Query: 1568 LAEPPYNILIEKVFMIGGGQILGEALNAPECDAIHMTEIESHMECDTFIPPVDLSVYQPW 1389
            LA  PY + IEKVF+IGGGQIL E+LNAPECDAIH+TEIE+  ECDTFIPP++LSV+QPW
Sbjct: 121  LASSPYCLSIEKVFVIGGGQILRESLNAPECDAIHITEIETSFECDTFIPPIELSVFQPW 180

Query: 1388 YSSTPEVENNIRYCFVTFVRLKTSIGGPTNSSPEVRCNGSILDFK----KFKVLNFTFLP 1221
            YSS P +ENNIR  FVT+VR++ S             NG + D      KF++  F+FLP
Sbjct: 181  YSSFPLIENNIRCSFVTYVRVRRSAAEYLYQD-----NGGMFDGNSNNTKFEIEKFSFLP 235

Query: 1220 RMIFEKHEEFLYLKLVQDIISNGNDKGDRTGTGTLSKFGCQMRFNLRKSFPLLTTKRVFW 1041
            +MIFE+HEE++YL+LV+DIISNGN K DRTGTGTLSKFGCQM FNLRKSFPLLTTK+VFW
Sbjct: 236  KMIFERHEEYMYLRLVEDIISNGNQKDDRTGTGTLSKFGCQMHFNLRKSFPLLTTKKVFW 295

Query: 1040 RGVVEELLWFISGSPNAKVLQEKGIHIWDGNASREYLDSIGLADREEGDLGPVYGFQWRH 861
            RGVVEELLWFISGS NAKVLQEKGIHIWDGNASR+YLDSIGL DREEGDLGP+YGFQWRH
Sbjct: 296  RGVVEELLWFISGSTNAKVLQEKGIHIWDGNASRDYLDSIGLTDREEGDLGPIYGFQWRH 355

Query: 860  FGARYTNMHADYTGQGFDQLLDAIDKIKNKPDDRRIILSAWNPSDLKLMALPPCHMFAQF 681
             GARYTNMHADY+GQGFDQLLD IDKIKNKPDDRRIILSAWNPSDLKLMALPPCHMFAQF
Sbjct: 356  HGARYTNMHADYSGQGFDQLLDVIDKIKNKPDDRRIILSAWNPSDLKLMALPPCHMFAQF 415

Query: 680  YVANGELSCQMYQRSADMGLGVPFNIASYALLTCMIAHVCGLVPGDLIHVIGDAHVYKTH 501
            YV NGELSCQMYQRSADMGLGVPFNIASYALLTCMIAHVC L+PGD IHVIGDAHVY+TH
Sbjct: 416  YVVNGELSCQMYQRSADMGLGVPFNIASYALLTCMIAHVCDLIPGDFIHVIGDAHVYRTH 475

Query: 500  ISPLQEQLXXXXXXXXXXXXXPQTKDIDSFVAADFELINYEPHQKLEMKLAV 345
            + PLQEQL             P  KDIDSFVA DF+L+ Y+PHQK+EMK+AV
Sbjct: 476  VRPLQEQLQKLPKPFPILKINPHKKDIDSFVATDFKLVGYDPHQKIEMKMAV 527


>ref|XP_011037491.1| PREDICTED: bifunctional dihydrofolate reductase-thymidylate synthase
            1-like [Populus euphratica]
            gi|743885202|ref|XP_011037492.1| PREDICTED: bifunctional
            dihydrofolate reductase-thymidylate synthase 1-like
            [Populus euphratica]
          Length = 528

 Score =  826 bits (2134), Expect = 0.0
 Identities = 399/529 (75%), Positives = 458/529 (86%), Gaps = 1/529 (0%)
 Frame = -1

Query: 1928 MSENSIACHSNGNADTQPPL-HRTYQVVVAATRDMGIGKDGKFPWKLPSDLKFFKEITMT 1752
            MS +S+A  SNGNA+TQ P   +TYQVVVAAT+DMGIGKDGK PWKLPSDLKFFK++T+T
Sbjct: 1    MSGDSVANLSNGNANTQQPAPQKTYQVVVAATKDMGIGKDGKLPWKLPSDLKFFKDLTLT 60

Query: 1751 TSDPEKKNAVIMGRKTWESIPPQFQPLPGRLNVILTRSGSFDMATAENVITCGSIPSALK 1572
            T D  KKNAVIMGRKTWESIP + +PLPGRLNV+LTRSGSFD+ATAENV+ CGS+ SAL+
Sbjct: 61   TMDSGKKNAVIMGRKTWESIPLEHRPLPGRLNVVLTRSGSFDIATAENVVICGSMSSALE 120

Query: 1571 LLAEPPYNILIEKVFMIGGGQILGEALNAPECDAIHMTEIESHMECDTFIPPVDLSVYQP 1392
            LLA  PY + IEKVF+IGGGQIL E+LNAP CDAIH+TEIE   +CDTFIP +D SV+QP
Sbjct: 121  LLAASPYCLSIEKVFVIGGGQILRESLNAPGCDAIHITEIEMDFDCDTFIPAIDTSVFQP 180

Query: 1391 WYSSTPEVENNIRYCFVTFVRLKTSIGGPTNSSPEVRCNGSILDFKKFKVLNFTFLPRMI 1212
            WYSS P VEN+IR+CF T+VR+++S     + +     +G+  +  KF+V+ F+FLP+M+
Sbjct: 181  WYSSFPNVENDIRHCFTTYVRVRSSTIESHSQNNGENSDGNS-ENSKFEVMKFSFLPKMV 239

Query: 1211 FEKHEEFLYLKLVQDIISNGNDKGDRTGTGTLSKFGCQMRFNLRKSFPLLTTKRVFWRGV 1032
            FE+HEE+LYL++VQDIIS+GN K DRTGTGTLSKFGCQMRFNLRK+FPLLTTK+VFWRGV
Sbjct: 240  FERHEEYLYLRMVQDIISDGNLKDDRTGTGTLSKFGCQMRFNLRKNFPLLTTKKVFWRGV 299

Query: 1031 VEELLWFISGSPNAKVLQEKGIHIWDGNASREYLDSIGLADREEGDLGPVYGFQWRHFGA 852
            VEELLWFISGS +AKVLQEKGIHIWDGNASR+YLDSIGL DREEGDLGPVYGFQWRHFGA
Sbjct: 300  VEELLWFISGSTSAKVLQEKGIHIWDGNASRDYLDSIGLKDREEGDLGPVYGFQWRHFGA 359

Query: 851  RYTNMHADYTGQGFDQLLDAIDKIKNKPDDRRIILSAWNPSDLKLMALPPCHMFAQFYVA 672
            RYT+MHADYTGQGFDQLLD IDKIKN P+DRRII+SAWNPSDLKLMALPPCHMFAQFYVA
Sbjct: 360  RYTDMHADYTGQGFDQLLDVIDKIKNNPNDRRIIISAWNPSDLKLMALPPCHMFAQFYVA 419

Query: 671  NGELSCQMYQRSADMGLGVPFNIASYALLTCMIAHVCGLVPGDLIHVIGDAHVYKTHISP 492
            NGELSCQMYQRSADMGLGVPFNIASYALLTC+IAHVC L+PGD +HVIGDAHVY THI P
Sbjct: 420  NGELSCQMYQRSADMGLGVPFNIASYALLTCIIAHVCDLIPGDFVHVIGDAHVYHTHIRP 479

Query: 491  LQEQLXXXXXXXXXXXXXPQTKDIDSFVAADFELINYEPHQKLEMKLAV 345
            LQEQL              + KDID+FVAADF+LI Y+PHQK+EMK+AV
Sbjct: 480  LQEQLRKLPKPFPILKINSEKKDIDTFVAADFKLIGYDPHQKIEMKMAV 528


>ref|XP_006384511.1| hypothetical protein POPTR_0004s16470g [Populus trichocarpa]
            gi|566166865|ref|XP_002306118.2| hypothetical protein
            POPTR_0004s16470g [Populus trichocarpa]
            gi|566166867|ref|XP_006384512.1| dihydrofolate
            reductase-thymidylate synthase family protein [Populus
            trichocarpa] gi|550341164|gb|ERP62308.1| hypothetical
            protein POPTR_0004s16470g [Populus trichocarpa]
            gi|550341165|gb|EEE86629.2| hypothetical protein
            POPTR_0004s16470g [Populus trichocarpa]
            gi|550341166|gb|ERP62309.1| dihydrofolate
            reductase-thymidylate synthase family protein [Populus
            trichocarpa]
          Length = 528

 Score =  825 bits (2132), Expect = 0.0
 Identities = 401/529 (75%), Positives = 459/529 (86%), Gaps = 1/529 (0%)
 Frame = -1

Query: 1928 MSENSIACHSNGNADTQPPLHR-TYQVVVAATRDMGIGKDGKFPWKLPSDLKFFKEITMT 1752
            MS +S+A  SNGNA+TQ    R TYQVVVAAT+DMGIGKDGK PWKLPSDLKFFK++T+T
Sbjct: 1    MSGDSVANLSNGNANTQQSDPRKTYQVVVAATKDMGIGKDGKLPWKLPSDLKFFKDLTLT 60

Query: 1751 TSDPEKKNAVIMGRKTWESIPPQFQPLPGRLNVILTRSGSFDMATAENVITCGSIPSALK 1572
            T D  KKNAVIMGRKTWESIP + +PLPGRLNV+LTRSGSFD+ATAENV+ CGS+ SAL+
Sbjct: 61   TMDSGKKNAVIMGRKTWESIPLEHRPLPGRLNVVLTRSGSFDIATAENVVICGSMGSALE 120

Query: 1571 LLAEPPYNILIEKVFMIGGGQILGEALNAPECDAIHMTEIESHMECDTFIPPVDLSVYQP 1392
            LLA  PY + IEKVF+IGGGQIL E+LNAP CDAIH+TEIE+  +CDTFIP +D SV+QP
Sbjct: 121  LLAASPYCLSIEKVFVIGGGQILRESLNAPGCDAIHITEIETDFDCDTFIPAIDTSVFQP 180

Query: 1391 WYSSTPEVENNIRYCFVTFVRLKTSIGGPTNSSPEVRCNGSILDFKKFKVLNFTFLPRMI 1212
            WYSS P+VEN+IR+CF T+VR+++S     + +     +G+  +  KF+V  F+FLP+M+
Sbjct: 181  WYSSFPKVENDIRHCFTTYVRVRSSTIESHSQNNGENSDGNS-ENSKFEVKKFSFLPKMV 239

Query: 1211 FEKHEEFLYLKLVQDIISNGNDKGDRTGTGTLSKFGCQMRFNLRKSFPLLTTKRVFWRGV 1032
            FE+HEE+LYL++VQDIIS+GN KGDRTGTGTLSKFGCQMRFNLRK+FPLLTTK+VFWRGV
Sbjct: 240  FERHEEYLYLRMVQDIISDGNLKGDRTGTGTLSKFGCQMRFNLRKNFPLLTTKKVFWRGV 299

Query: 1031 VEELLWFISGSPNAKVLQEKGIHIWDGNASREYLDSIGLADREEGDLGPVYGFQWRHFGA 852
            VEELLWFISGS +AKVLQEKGIHIWDGNASREYLDSIGL DREEGDLGPVYGFQWRHFGA
Sbjct: 300  VEELLWFISGSTSAKVLQEKGIHIWDGNASREYLDSIGLKDREEGDLGPVYGFQWRHFGA 359

Query: 851  RYTNMHADYTGQGFDQLLDAIDKIKNKPDDRRIILSAWNPSDLKLMALPPCHMFAQFYVA 672
            RYT+MHADYTGQGFDQLLD IDKIKN P+DRRII+SAWNPSDLKLMALPPCHMFAQFYVA
Sbjct: 360  RYTDMHADYTGQGFDQLLDVIDKIKNNPNDRRIIISAWNPSDLKLMALPPCHMFAQFYVA 419

Query: 671  NGELSCQMYQRSADMGLGVPFNIASYALLTCMIAHVCGLVPGDLIHVIGDAHVYKTHISP 492
            NGELSCQMYQRSADMGLGVPFNIASYALLTC+IAHVC L+PGD +HVIGDAHVY THI P
Sbjct: 420  NGELSCQMYQRSADMGLGVPFNIASYALLTCIIAHVCDLIPGDFVHVIGDAHVYHTHIRP 479

Query: 491  LQEQLXXXXXXXXXXXXXPQTKDIDSFVAADFELINYEPHQKLEMKLAV 345
            LQEQL              + KDID+FVAADF+LI Y+PHQK+EMK+AV
Sbjct: 480  LQEQLRKLPKPFPILKINSEKKDIDTFVAADFKLIGYDPHQKIEMKMAV 528


>ref|XP_008377275.1| PREDICTED: bifunctional dihydrofolate reductase-thymidylate
            synthase-like [Malus domestica]
          Length = 526

 Score =  824 bits (2129), Expect = 0.0
 Identities = 396/522 (75%), Positives = 457/522 (87%), Gaps = 3/522 (0%)
 Frame = -1

Query: 1901 SNGNADTQPPLHRTYQVVVAATRDMGIGKDGKFPWKLPSDLKFFKEITMTTSDPEKKNAV 1722
            +NGN +TQP   RTYQVVVAATR+MGIGKDGK PW+LPSDLKFFK++T+TTSDP KKNA+
Sbjct: 9    ANGNGNTQPNPQRTYQVVVAATREMGIGKDGKLPWRLPSDLKFFKDVTVTTSDPAKKNAI 68

Query: 1721 IMGRKTWESIPPQFQPLPGRLNVILTRSGSFDMATAENVITCGSIPSALKLLAEPPYNIL 1542
            IMGRKTWESIP + QPLPGRLNV+LTRSGSFD+ATAENV+ CGS+ SAL+LLA  PY + 
Sbjct: 69   IMGRKTWESIPSEHQPLPGRLNVVLTRSGSFDIATAENVVICGSMASALELLAASPYCLS 128

Query: 1541 IEKVFMIGGGQILGEALNAPECDAIHMTEIESHMECDTFIPPVDLSVYQPWYSSTPEVEN 1362
            IE+VF+IGGGQIL EALNAP C+AIH+TEIE+++ECDTFIP +D SV+QPWYSS P+VEN
Sbjct: 129  IERVFLIGGGQILREALNAPGCEAIHITEIETNIECDTFIPAIDSSVFQPWYSSFPKVEN 188

Query: 1361 NIRYCFVTFVRLKTSIGGPTNSSPEVRCN---GSILDFKKFKVLNFTFLPRMIFEKHEEF 1191
            +IR+ F T+VR+++S       + ++  N   GSI    K +V NF+FLP+MIFEKHEE 
Sbjct: 189  SIRHSFTTYVRVRSSAVESLCENNDLISNSKSGSI----KCEVKNFSFLPKMIFEKHEEH 244

Query: 1190 LYLKLVQDIISNGNDKGDRTGTGTLSKFGCQMRFNLRKSFPLLTTKRVFWRGVVEELLWF 1011
            +YL+LV++++S+G  K DRTGTGTLSKFGCQMRFNLR++FPLLTTK+VFWRGVVEELLWF
Sbjct: 245  MYLRLVREVLSDGTSKDDRTGTGTLSKFGCQMRFNLRRTFPLLTTKKVFWRGVVEELLWF 304

Query: 1010 ISGSPNAKVLQEKGIHIWDGNASREYLDSIGLADREEGDLGPVYGFQWRHFGARYTNMHA 831
            ISGS NAKVLQEKGIHIWDGNASR+YLDS+GL D+EEGDLGPVYGFQWRHFGARYT+MHA
Sbjct: 305  ISGSTNAKVLQEKGIHIWDGNASRDYLDSVGLTDKEEGDLGPVYGFQWRHFGARYTDMHA 364

Query: 830  DYTGQGFDQLLDAIDKIKNKPDDRRIILSAWNPSDLKLMALPPCHMFAQFYVANGELSCQ 651
            DYTGQGFDQLLD IDKIKNKPDDRRIILSAWNPSDLKLMALPPCHMFAQFYVANGELSCQ
Sbjct: 365  DYTGQGFDQLLDVIDKIKNKPDDRRIILSAWNPSDLKLMALPPCHMFAQFYVANGELSCQ 424

Query: 650  MYQRSADMGLGVPFNIASYALLTCMIAHVCGLVPGDLIHVIGDAHVYKTHISPLQEQLXX 471
            MYQRSAD+GLGVPFNIASYALLTCMIAHVCGLVPGD IH +GDAHVY+THI PL+EQL  
Sbjct: 425  MYQRSADLGLGVPFNIASYALLTCMIAHVCGLVPGDFIHALGDAHVYRTHIRPLKEQLEK 484

Query: 470  XXXXXXXXXXXPQTKDIDSFVAADFELINYEPHQKLEMKLAV 345
                       P+ K+IDSFVAADF+LI Y+PHQK+EMK+AV
Sbjct: 485  LPKPFPILKINPEKKNIDSFVAADFKLIGYDPHQKIEMKMAV 526


>emb|CDP07483.1| unnamed protein product [Coffea canephora]
          Length = 527

 Score =  823 bits (2126), Expect = 0.0
 Identities = 395/528 (74%), Positives = 451/528 (85%)
 Frame = -1

Query: 1928 MSENSIACHSNGNADTQPPLHRTYQVVVAATRDMGIGKDGKFPWKLPSDLKFFKEITMTT 1749
            MS +S  C S+G+A  +P   R+YQVVVAATRD+GIGKDGK PW+LPSDLKFFKEIT+TT
Sbjct: 1    MSADSHMCRSDGDARIKPLSLRSYQVVVAATRDLGIGKDGKLPWRLPSDLKFFKEITVTT 60

Query: 1748 SDPEKKNAVIMGRKTWESIPPQFQPLPGRLNVILTRSGSFDMATAENVITCGSIPSALKL 1569
            +DP K+NAV+MGRKTWESIPPQF+PLPGRLN++LTRSGS   A  +NV+ CGSI SAL+L
Sbjct: 61   TDPVKRNAVVMGRKTWESIPPQFRPLPGRLNIVLTRSGSLGPAIDDNVVCCGSISSALEL 120

Query: 1568 LAEPPYNILIEKVFMIGGGQILGEALNAPECDAIHMTEIESHMECDTFIPPVDLSVYQPW 1389
            LAE PY   +EKVF+IGGGQIL EALNAPEC+AIHMT IE+ +ECD FIPPVD S++QPW
Sbjct: 121  LAESPYCSSVEKVFVIGGGQILREALNAPECEAIHMTVIEADIECDAFIPPVDGSLFQPW 180

Query: 1388 YSSTPEVENNIRYCFVTFVRLKTSIGGPTNSSPEVRCNGSILDFKKFKVLNFTFLPRMIF 1209
            YSS P VENNIR+CFVT+VR+ +S   P +   + + N S  D K+F V +F+FLP+ +F
Sbjct: 181  YSSPPTVENNIRHCFVTYVRVMSSAVEPVDLHQQAKSNRSS-DSKRFNVSSFSFLPKTVF 239

Query: 1208 EKHEEFLYLKLVQDIISNGNDKGDRTGTGTLSKFGCQMRFNLRKSFPLLTTKRVFWRGVV 1029
            +KH+EFLYL+LVQDII+ GN K DRTGTGTLSKFGCQMRFNLR+SFPLLTTKR+FW+GVV
Sbjct: 240  DKHDEFLYLRLVQDIIATGNHKDDRTGTGTLSKFGCQMRFNLRRSFPLLTTKRIFWQGVV 299

Query: 1028 EELLWFISGSPNAKVLQEKGIHIWDGNASREYLDSIGLADREEGDLGPVYGFQWRHFGAR 849
            EELLWFISGS NAKVLQEKGIHIWDGNASREYLDSI L DRE GDLGP+YGFQWRHFGAR
Sbjct: 300  EELLWFISGSTNAKVLQEKGIHIWDGNASREYLDSIDLEDREVGDLGPIYGFQWRHFGAR 359

Query: 848  YTNMHADYTGQGFDQLLDAIDKIKNKPDDRRIILSAWNPSDLKLMALPPCHMFAQFYVAN 669
            YT MHADY GQGFDQLLD ID+IK  P+DRRI+LSAWNPSDLKL ALPPCH FAQFYVAN
Sbjct: 360  YTGMHADYKGQGFDQLLDVIDRIKRNPNDRRIVLSAWNPSDLKLTALPPCHTFAQFYVAN 419

Query: 668  GELSCQMYQRSADMGLGVPFNIASYALLTCMIAHVCGLVPGDLIHVIGDAHVYKTHISPL 489
            GELSCQMYQRSADMGLGVPFNIASYALLTCMIAHVCGLVPGD IH++GDAHVYKTH+ PL
Sbjct: 420  GELSCQMYQRSADMGLGVPFNIASYALLTCMIAHVCGLVPGDFIHILGDAHVYKTHVVPL 479

Query: 488  QEQLXXXXXXXXXXXXXPQTKDIDSFVAADFELINYEPHQKLEMKLAV 345
            QEQL             P+ KDIDSFVA+DFELI Y+PHQK+EM++AV
Sbjct: 480  QEQLQKFPKPFPILKINPEKKDIDSFVASDFELIGYDPHQKIEMRMAV 527


>ref|XP_012480346.1| PREDICTED: bifunctional dihydrofolate reductase-thymidylate
            synthase-like isoform X1 [Gossypium raimondii]
            gi|823160980|ref|XP_012480347.1| PREDICTED: bifunctional
            dihydrofolate reductase-thymidylate synthase-like isoform
            X1 [Gossypium raimondii] gi|823160982|ref|XP_012480348.1|
            PREDICTED: bifunctional dihydrofolate
            reductase-thymidylate synthase-like isoform X1 [Gossypium
            raimondii] gi|823160984|ref|XP_012480349.1| PREDICTED:
            bifunctional dihydrofolate reductase-thymidylate
            synthase-like isoform X1 [Gossypium raimondii]
            gi|763765277|gb|KJB32531.1| hypothetical protein
            B456_005G245400 [Gossypium raimondii]
            gi|763765278|gb|KJB32532.1| hypothetical protein
            B456_005G245400 [Gossypium raimondii]
            gi|763765279|gb|KJB32533.1| hypothetical protein
            B456_005G245400 [Gossypium raimondii]
          Length = 531

 Score =  823 bits (2125), Expect = 0.0
 Identities = 397/521 (76%), Positives = 448/521 (85%), Gaps = 1/521 (0%)
 Frame = -1

Query: 1904 HSNGNADTQPPLHRTYQVVVAATRDMGIGKDGKFPWKLPSDLKFFKEITMTTSDPEKKNA 1725
            +SNGN + QP   RTYQ VVAAT+D GIGKDGK PWKLPSDLKFFK++T+TTSD  KKNA
Sbjct: 13   NSNGNGNVQPEPRRTYQTVVAATKDWGIGKDGKLPWKLPSDLKFFKDVTLTTSDSGKKNA 72

Query: 1724 VIMGRKTWESIPPQFQPLPGRLNVILTRSGSFDMATAENVITCGSIPSALKLLAEPPYNI 1545
            VIMGRKTWESIP Q++PLPGRLNV+LTRSGSFD+ATAENV+ CGS+ SAL+LLA  PY +
Sbjct: 73   VIMGRKTWESIPLQYRPLPGRLNVVLTRSGSFDIATAENVVICGSMTSALELLAASPYCL 132

Query: 1544 LIEKVFMIGGGQILGEALNAPECDAIHMTEIESHMECDTFIPPVDLSVYQPWYSSTPEVE 1365
             IEKVF+IGGGQI  E+LNA  CDAIH+TEIE+ +ECDTF+P +D SV+QPWYSS P VE
Sbjct: 133  SIEKVFVIGGGQIFRESLNAAGCDAIHITEIETSIECDTFMPAIDSSVFQPWYSSFPVVE 192

Query: 1364 NNIRYCFVTFVRLKTS-IGGPTNSSPEVRCNGSILDFKKFKVLNFTFLPRMIFEKHEEFL 1188
            NNIRYCF T+VR++TS +   +    +V  N   LD  KF++ NF+FLP+MIFEKHEE+L
Sbjct: 193  NNIRYCFTTYVRVRTSAVEHFSQDCDQVLDNK--LDSSKFEIQNFSFLPKMIFEKHEEYL 250

Query: 1187 YLKLVQDIISNGNDKGDRTGTGTLSKFGCQMRFNLRKSFPLLTTKRVFWRGVVEELLWFI 1008
            YL ++QDIIS GN KGDRTGTGTLSKFGCQMRFNLRK+FPLLTTK+VFWRGVVEELLWFI
Sbjct: 251  YLNMIQDIISEGNLKGDRTGTGTLSKFGCQMRFNLRKTFPLLTTKKVFWRGVVEELLWFI 310

Query: 1007 SGSPNAKVLQEKGIHIWDGNASREYLDSIGLADREEGDLGPVYGFQWRHFGARYTNMHAD 828
            SGS NAKVLQEKGIHIWDGNASRE+LDSIGL DREEGDLGPVYGFQWRHFGARYT+MHAD
Sbjct: 311  SGSTNAKVLQEKGIHIWDGNASREFLDSIGLTDREEGDLGPVYGFQWRHFGARYTDMHAD 370

Query: 827  YTGQGFDQLLDAIDKIKNKPDDRRIILSAWNPSDLKLMALPPCHMFAQFYVANGELSCQM 648
            YTGQGFDQLLD IDKIKN P+DRRIILSAWNPSDLKLMALPPCHMFAQFYVANGELSCQM
Sbjct: 371  YTGQGFDQLLDVIDKIKNNPNDRRIILSAWNPSDLKLMALPPCHMFAQFYVANGELSCQM 430

Query: 647  YQRSADMGLGVPFNIASYALLTCMIAHVCGLVPGDLIHVIGDAHVYKTHISPLQEQLXXX 468
            YQRS DMGLGVPFNIASYALLTCMIAHVC LVPGD +HV+GD HVY TH+ PLQEQL   
Sbjct: 431  YQRSCDMGLGVPFNIASYALLTCMIAHVCDLVPGDFVHVLGDTHVYSTHVRPLQEQLQKL 490

Query: 467  XXXXXXXXXXPQTKDIDSFVAADFELINYEPHQKLEMKLAV 345
                      P+  +IDSFVA+DF+LI Y+PH+K+EM +AV
Sbjct: 491  PKPFPILKINPEKNNIDSFVASDFKLIGYDPHKKIEMTMAV 531


>ref|XP_010664719.1| PREDICTED: putative bifunctional dihydrofolate reductase-thymidylate
            synthase isoform X2 [Vitis vinifera]
          Length = 567

 Score =  823 bits (2125), Expect = 0.0
 Identities = 403/559 (72%), Positives = 459/559 (82%)
 Frame = -1

Query: 2021 FFSSASVTPFTRSFRVPNIFSKQRSYCEYSVMSENSIACHSNGNADTQPPLHRTYQVVVA 1842
            F    S +  +R F V N+ +K+R    YSV+S +S   + NG+A   P   RTYQVVVA
Sbjct: 13   FARPGSASALSRLFTVLNVIAKRRVQTSYSVLSGDSAMSYPNGDARVHPVPQRTYQVVVA 72

Query: 1841 ATRDMGIGKDGKFPWKLPSDLKFFKEITMTTSDPEKKNAVIMGRKTWESIPPQFQPLPGR 1662
            AT  MGIGKDGK PW LPSDLKFFKE+TMTTSDP KKNAV+MGRKTWESIP  ++PLPGR
Sbjct: 73   ATHKMGIGKDGKLPWNLPSDLKFFKELTMTTSDPGKKNAVVMGRKTWESIPLNYRPLPGR 132

Query: 1661 LNVILTRSGSFDMATAENVITCGSIPSALKLLAEPPYNILIEKVFMIGGGQILGEALNAP 1482
            LNV+LTRSGSFD AT ENV+ CGS+PSALKLLAE PY + I+KVF+IGGGQIL EALNAP
Sbjct: 133  LNVVLTRSGSFDNATVENVVICGSMPSALKLLAESPYCLSIDKVFVIGGGQILREALNAP 192

Query: 1481 ECDAIHMTEIESHMECDTFIPPVDLSVYQPWYSSTPEVENNIRYCFVTFVRLKTSIGGPT 1302
             CDAIH+T+IE+ +ECDTFIP +D SV+ PWYSS P +ENNI Y FVT+VR+++S     
Sbjct: 193  GCDAIHITKIETSIECDTFIPTIDTSVFHPWYSSVPLLENNILYSFVTYVRVRSSALESF 252

Query: 1301 NSSPEVRCNGSILDFKKFKVLNFTFLPRMIFEKHEEFLYLKLVQDIISNGNDKGDRTGTG 1122
              S  V  NG  +   K K+  FTFLP+MIFE+H+EF+YL+ +++IIS+G  K D+TGTG
Sbjct: 253  ALSSGVNFNGGSVP-NKLKIQGFTFLPKMIFERHDEFMYLRQLKEIISSGAHKADKTGTG 311

Query: 1121 TLSKFGCQMRFNLRKSFPLLTTKRVFWRGVVEELLWFISGSPNAKVLQEKGIHIWDGNAS 942
            T+SKFGCQMRFNLR SFPLLTTKRVFWRGVVEELLWFISGS NAK   +K IHIWDGNAS
Sbjct: 312  TVSKFGCQMRFNLRLSFPLLTTKRVFWRGVVEELLWFISGSTNAK---KKDIHIWDGNAS 368

Query: 941  REYLDSIGLADREEGDLGPVYGFQWRHFGARYTNMHADYTGQGFDQLLDAIDKIKNKPDD 762
            REYLDSIGL DREEGDLGP+YGFQWRHFGARYTNMHADY G+GFDQLLD IDKIKNKPDD
Sbjct: 369  REYLDSIGLTDREEGDLGPIYGFQWRHFGARYTNMHADYMGKGFDQLLDVIDKIKNKPDD 428

Query: 761  RRIILSAWNPSDLKLMALPPCHMFAQFYVANGELSCQMYQRSADMGLGVPFNIASYALLT 582
            RRIILS+WNPSDLKLMALPPCHMFAQFYVANGELSCQMYQRSADMGLGVPFNIASYALLT
Sbjct: 429  RRIILSSWNPSDLKLMALPPCHMFAQFYVANGELSCQMYQRSADMGLGVPFNIASYALLT 488

Query: 581  CMIAHVCGLVPGDLIHVIGDAHVYKTHISPLQEQLXXXXXXXXXXXXXPQTKDIDSFVAA 402
            CMIAHVCG++PGD I +IGDAH+YKTHI PL+EQL             PQ KDI+SFVAA
Sbjct: 489  CMIAHVCGILPGDFILIIGDAHIYKTHIRPLEEQLQKLPKPFPILKINPQKKDIESFVAA 548

Query: 401  DFELINYEPHQKLEMKLAV 345
            DFELI Y PHQK+EMK++V
Sbjct: 549  DFELIGYNPHQKIEMKMSV 567


>gb|KDO47901.1| hypothetical protein CISIN_1g009747mg [Citrus sinensis]
            gi|641828763|gb|KDO47902.1| hypothetical protein
            CISIN_1g009747mg [Citrus sinensis]
          Length = 527

 Score =  823 bits (2125), Expect = 0.0
 Identities = 401/532 (75%), Positives = 452/532 (84%), Gaps = 4/532 (0%)
 Frame = -1

Query: 1928 MSENSIACHSNGNADTQPPLHRTYQVVVAATRDMGIGKDGKFPWKLPSDLKFFKEITMTT 1749
            M+ +S    SNGN  TQP   R+YQVVVAATRDMGIGKDGK PWKLPSDLKFFKEIT  T
Sbjct: 1    MAADSKTSLSNGNVSTQPNPKRSYQVVVAATRDMGIGKDGKLPWKLPSDLKFFKEITQIT 60

Query: 1748 SDPEKKNAVIMGRKTWESIPPQFQPLPGRLNVILTRSGSFDMATAENVITCGSIPSALKL 1569
            SD  K+NAVIMGRKTWESIP + +PLPGRLNV+LTRSGSFD+AT ENV+ CGSI SAL+L
Sbjct: 61   SDAGKRNAVIMGRKTWESIPLEHRPLPGRLNVVLTRSGSFDIATVENVVICGSIGSALEL 120

Query: 1568 LAEPPYNILIEKVFMIGGGQILGEALNAPECDAIHMTEIESHMECDTFIPPVDLSVYQPW 1389
            LA  PY + IEKVF+IGGGQIL EALNAPECDAIH+TEIE+ +ECDTFIP +D SV+QPW
Sbjct: 121  LAASPYCLSIEKVFVIGGGQILSEALNAPECDAIHITEIETRIECDTFIPSIDSSVFQPW 180

Query: 1388 YSSTPEVENNIRYCFVTFVRLKTSIGGPTNSSPEVRCNGSILDFK----KFKVLNFTFLP 1221
            YSS P VENNIRYC  T+VR++++     + + ++     +LD K    KF+V  F+FLP
Sbjct: 181  YSSFPIVENNIRYCLSTYVRVRSAAVESLSQNNDI-----VLDSKTNSDKFEVKQFSFLP 235

Query: 1220 RMIFEKHEEFLYLKLVQDIISNGNDKGDRTGTGTLSKFGCQMRFNLRKSFPLLTTKRVFW 1041
            +M+FEKHEE+LYL+LVQDIIS+GN K DRTGTGTLSKFGCQMR+NLR +FPLLTTK+VFW
Sbjct: 236  KMVFEKHEEYLYLRLVQDIISDGNLKDDRTGTGTLSKFGCQMRYNLRTTFPLLTTKKVFW 295

Query: 1040 RGVVEELLWFISGSPNAKVLQEKGIHIWDGNASREYLDSIGLADREEGDLGPVYGFQWRH 861
            RGVVEELLWFISGS NAKVLQEK IHIWDGNASREYLDS+GL DREEGDLGPVYGFQWRH
Sbjct: 296  RGVVEELLWFISGSTNAKVLQEKDIHIWDGNASREYLDSVGLTDREEGDLGPVYGFQWRH 355

Query: 860  FGARYTNMHADYTGQGFDQLLDAIDKIKNKPDDRRIILSAWNPSDLKLMALPPCHMFAQF 681
            FGARYTNMHADY+GQGFDQLLD I+KIKN P+DRRI+LSAWNPSDLKLMALPPCHMFAQF
Sbjct: 356  FGARYTNMHADYSGQGFDQLLDVINKIKNNPNDRRIVLSAWNPSDLKLMALPPCHMFAQF 415

Query: 680  YVANGELSCQMYQRSADMGLGVPFNIASYALLTCMIAHVCGLVPGDLIHVIGDAHVYKTH 501
            Y+ANGELSCQMYQRSADMGLGVPFNIASYALLTCMIAHVC L PGD IHVIGDAHVY+ H
Sbjct: 416  YMANGELSCQMYQRSADMGLGVPFNIASYALLTCMIAHVCDLAPGDFIHVIGDAHVYRNH 475

Query: 500  ISPLQEQLXXXXXXXXXXXXXPQTKDIDSFVAADFELINYEPHQKLEMKLAV 345
            + PL+EQL             P+ KDIDSFVA DF+LI Y+PHQK+EMK+AV
Sbjct: 476  VRPLEEQLQKLPKPFPILKINPEKKDIDSFVAEDFKLIGYDPHQKIEMKMAV 527


>ref|XP_012067239.1| PREDICTED: bifunctional dihydrofolate reductase-thymidylate synthase
            1 [Jatropha curcas] gi|643735124|gb|KDP41765.1|
            hypothetical protein JCGZ_26783 [Jatropha curcas]
          Length = 525

 Score =  822 bits (2123), Expect = 0.0
 Identities = 395/528 (74%), Positives = 453/528 (85%)
 Frame = -1

Query: 1928 MSENSIACHSNGNADTQPPLHRTYQVVVAATRDMGIGKDGKFPWKLPSDLKFFKEITMTT 1749
            M+ +S A  SNG A+ Q    RTYQVVVAATRDMGIGK+GK PW+LPSDLKFFK++T+TT
Sbjct: 1    MAGDSKASLSNGTANIQSDPRRTYQVVVAATRDMGIGKEGKLPWRLPSDLKFFKDVTLTT 60

Query: 1748 SDPEKKNAVIMGRKTWESIPPQFQPLPGRLNVILTRSGSFDMATAENVITCGSIPSALKL 1569
            SD  +KNAVIMGRKTWESIP + +PLPGRLNV+LTRSGSFD+ATAENV+ CGS+ SAL+L
Sbjct: 61   SDSGRKNAVIMGRKTWESIPLEHRPLPGRLNVVLTRSGSFDIATAENVVICGSLTSALEL 120

Query: 1568 LAEPPYNILIEKVFMIGGGQILGEALNAPECDAIHMTEIESHMECDTFIPPVDLSVYQPW 1389
            LA  PY + IEKVF+IGGGQIL E+LNAP CDAIH+TEIE+ ++CDTFIP +D SV+QPW
Sbjct: 121  LAASPYCLSIEKVFIIGGGQILRESLNAPGCDAIHITEIETSIDCDTFIPKIDSSVFQPW 180

Query: 1388 YSSTPEVENNIRYCFVTFVRLKTSIGGPTNSSPEVRCNGSILDFKKFKVLNFTFLPRMIF 1209
            YSS P VENN+RYCF T+VR++ S          +  + S +   KF+V  F+FLP+M+F
Sbjct: 181  YSSFPIVENNVRYCFATYVRVRVSAVESHGQDNGLSSDNSYI---KFEVKKFSFLPKMVF 237

Query: 1208 EKHEEFLYLKLVQDIISNGNDKGDRTGTGTLSKFGCQMRFNLRKSFPLLTTKRVFWRGVV 1029
            E+HEEFLYL+LVQDIIS+GN K DRTGTGTLSKFGCQMRFNLR++FPLLTTK+VFWRGVV
Sbjct: 238  ERHEEFLYLRLVQDIISDGNLKDDRTGTGTLSKFGCQMRFNLRRTFPLLTTKKVFWRGVV 297

Query: 1028 EELLWFISGSPNAKVLQEKGIHIWDGNASREYLDSIGLADREEGDLGPVYGFQWRHFGAR 849
            EELLWFISGS N KVLQEKGIHIWDGNASR+YLD IGL DREEGDLGPVYGFQWRHFGAR
Sbjct: 298  EELLWFISGSTNCKVLQEKGIHIWDGNASRDYLDGIGLKDREEGDLGPVYGFQWRHFGAR 357

Query: 848  YTNMHADYTGQGFDQLLDAIDKIKNKPDDRRIILSAWNPSDLKLMALPPCHMFAQFYVAN 669
            YT+MHADYTGQGFDQLLD IDKIKN PDDRRIILSAWNPSDLKLMALPPCHMFAQFYVAN
Sbjct: 358  YTDMHADYTGQGFDQLLDVIDKIKNNPDDRRIILSAWNPSDLKLMALPPCHMFAQFYVAN 417

Query: 668  GELSCQMYQRSADMGLGVPFNIASYALLTCMIAHVCGLVPGDLIHVIGDAHVYKTHISPL 489
            GELSCQMYQRSADMGLGVPFNIASYALLTC+++HVC LVPGD +HV+GDAHVY+TH+ PL
Sbjct: 418  GELSCQMYQRSADMGLGVPFNIASYALLTCIVSHVCDLVPGDFVHVLGDAHVYRTHVRPL 477

Query: 488  QEQLXXXXXXXXXXXXXPQTKDIDSFVAADFELINYEPHQKLEMKLAV 345
            QEQL             P+ K+IDSFVAADF+LI Y+PHQK+EMK+A+
Sbjct: 478  QEQLQKPPKPFPILKINPEKKNIDSFVAADFKLIGYDPHQKIEMKMAI 525


>ref|XP_009378649.1| PREDICTED: bifunctional dihydrofolate reductase-thymidylate
            synthase-like isoform X2 [Pyrus x bretschneideri]
            gi|694407862|ref|XP_009378650.1| PREDICTED: bifunctional
            dihydrofolate reductase-thymidylate synthase-like isoform
            X2 [Pyrus x bretschneideri]
          Length = 526

 Score =  822 bits (2122), Expect = 0.0
 Identities = 395/522 (75%), Positives = 456/522 (87%), Gaps = 3/522 (0%)
 Frame = -1

Query: 1901 SNGNADTQPPLHRTYQVVVAATRDMGIGKDGKFPWKLPSDLKFFKEITMTTSDPEKKNAV 1722
            +NGN +TQP   RTYQVVVAATR+MGIGKDGK PW+LPSDLKFFK++T+TTSDP KKNA+
Sbjct: 9    ANGNGNTQPNPQRTYQVVVAATREMGIGKDGKLPWRLPSDLKFFKDVTVTTSDPAKKNAI 68

Query: 1721 IMGRKTWESIPPQFQPLPGRLNVILTRSGSFDMATAENVITCGSIPSALKLLAEPPYNIL 1542
            IMGRKTWESIP + QPLPGRLNV+LTRSGSFD+ATAENV+ CGS+ SAL+LLA  PY + 
Sbjct: 69   IMGRKTWESIPSEHQPLPGRLNVVLTRSGSFDIATAENVVICGSMASALELLAASPYCLS 128

Query: 1541 IEKVFMIGGGQILGEALNAPECDAIHMTEIESHMECDTFIPPVDLSVYQPWYSSTPEVEN 1362
            IE+VF+IGGGQIL EALNAP C+AIH+TEIE+++ECDTFIP +D SV+QPWYSS P+VEN
Sbjct: 129  IERVFLIGGGQILREALNAPGCEAIHITEIETNIECDTFIPAIDSSVFQPWYSSFPKVEN 188

Query: 1361 NIRYCFVTFVRLKTSIGGPTNSSPEVRCN---GSILDFKKFKVLNFTFLPRMIFEKHEEF 1191
            +IR+ F T+VR+++S       + ++  N   GSI    K +V NF+FLP+MIFEKHEE 
Sbjct: 189  SIRHSFTTYVRVRSSAVESLCENSDLISNSKSGSI----KCEVKNFSFLPKMIFEKHEEH 244

Query: 1190 LYLKLVQDIISNGNDKGDRTGTGTLSKFGCQMRFNLRKSFPLLTTKRVFWRGVVEELLWF 1011
            +YL+LV++I+S+G  K DRTGTGTLSKFGCQMRFNLR++FPLLTTK+VFWRGVVEELLWF
Sbjct: 245  MYLRLVREILSDGTSKDDRTGTGTLSKFGCQMRFNLRRTFPLLTTKKVFWRGVVEELLWF 304

Query: 1010 ISGSPNAKVLQEKGIHIWDGNASREYLDSIGLADREEGDLGPVYGFQWRHFGARYTNMHA 831
            ISGS NAKVLQEKGIHIWDGNAS++YLDS+GL D+EEGDLGPVYGFQWRHFGARYT+MHA
Sbjct: 305  ISGSTNAKVLQEKGIHIWDGNASKDYLDSVGLTDKEEGDLGPVYGFQWRHFGARYTDMHA 364

Query: 830  DYTGQGFDQLLDAIDKIKNKPDDRRIILSAWNPSDLKLMALPPCHMFAQFYVANGELSCQ 651
            DYTGQGFDQLLD IDKIKN PDDRRIILSAWNPSDLKLMALPPCHMFAQFYVANGELSCQ
Sbjct: 365  DYTGQGFDQLLDVIDKIKNNPDDRRIILSAWNPSDLKLMALPPCHMFAQFYVANGELSCQ 424

Query: 650  MYQRSADMGLGVPFNIASYALLTCMIAHVCGLVPGDLIHVIGDAHVYKTHISPLQEQLXX 471
            MYQRSAD+GLGVPFNIASYALLTCMIAHVCGLVPGD IH +GDAHVY+THI PL+EQL  
Sbjct: 425  MYQRSADIGLGVPFNIASYALLTCMIAHVCGLVPGDFIHALGDAHVYRTHIRPLKEQLEK 484

Query: 470  XXXXXXXXXXXPQTKDIDSFVAADFELINYEPHQKLEMKLAV 345
                       P+ K+IDSFVAADF+LI Y+PHQK+EMK+AV
Sbjct: 485  LPKPFPILKINPEKKNIDSFVAADFKLIGYDPHQKIEMKMAV 526


>ref|XP_009378647.1| PREDICTED: bifunctional dihydrofolate reductase-thymidylate
            synthase-like isoform X1 [Pyrus x bretschneideri]
            gi|694407858|ref|XP_009378648.1| PREDICTED: bifunctional
            dihydrofolate reductase-thymidylate synthase-like isoform
            X1 [Pyrus x bretschneideri]
          Length = 558

 Score =  822 bits (2122), Expect = 0.0
 Identities = 395/522 (75%), Positives = 456/522 (87%), Gaps = 3/522 (0%)
 Frame = -1

Query: 1901 SNGNADTQPPLHRTYQVVVAATRDMGIGKDGKFPWKLPSDLKFFKEITMTTSDPEKKNAV 1722
            +NGN +TQP   RTYQVVVAATR+MGIGKDGK PW+LPSDLKFFK++T+TTSDP KKNA+
Sbjct: 41   ANGNGNTQPNPQRTYQVVVAATREMGIGKDGKLPWRLPSDLKFFKDVTVTTSDPAKKNAI 100

Query: 1721 IMGRKTWESIPPQFQPLPGRLNVILTRSGSFDMATAENVITCGSIPSALKLLAEPPYNIL 1542
            IMGRKTWESIP + QPLPGRLNV+LTRSGSFD+ATAENV+ CGS+ SAL+LLA  PY + 
Sbjct: 101  IMGRKTWESIPSEHQPLPGRLNVVLTRSGSFDIATAENVVICGSMASALELLAASPYCLS 160

Query: 1541 IEKVFMIGGGQILGEALNAPECDAIHMTEIESHMECDTFIPPVDLSVYQPWYSSTPEVEN 1362
            IE+VF+IGGGQIL EALNAP C+AIH+TEIE+++ECDTFIP +D SV+QPWYSS P+VEN
Sbjct: 161  IERVFLIGGGQILREALNAPGCEAIHITEIETNIECDTFIPAIDSSVFQPWYSSFPKVEN 220

Query: 1361 NIRYCFVTFVRLKTSIGGPTNSSPEVRCN---GSILDFKKFKVLNFTFLPRMIFEKHEEF 1191
            +IR+ F T+VR+++S       + ++  N   GSI    K +V NF+FLP+MIFEKHEE 
Sbjct: 221  SIRHSFTTYVRVRSSAVESLCENSDLISNSKSGSI----KCEVKNFSFLPKMIFEKHEEH 276

Query: 1190 LYLKLVQDIISNGNDKGDRTGTGTLSKFGCQMRFNLRKSFPLLTTKRVFWRGVVEELLWF 1011
            +YL+LV++I+S+G  K DRTGTGTLSKFGCQMRFNLR++FPLLTTK+VFWRGVVEELLWF
Sbjct: 277  MYLRLVREILSDGTSKDDRTGTGTLSKFGCQMRFNLRRTFPLLTTKKVFWRGVVEELLWF 336

Query: 1010 ISGSPNAKVLQEKGIHIWDGNASREYLDSIGLADREEGDLGPVYGFQWRHFGARYTNMHA 831
            ISGS NAKVLQEKGIHIWDGNAS++YLDS+GL D+EEGDLGPVYGFQWRHFGARYT+MHA
Sbjct: 337  ISGSTNAKVLQEKGIHIWDGNASKDYLDSVGLTDKEEGDLGPVYGFQWRHFGARYTDMHA 396

Query: 830  DYTGQGFDQLLDAIDKIKNKPDDRRIILSAWNPSDLKLMALPPCHMFAQFYVANGELSCQ 651
            DYTGQGFDQLLD IDKIKN PDDRRIILSAWNPSDLKLMALPPCHMFAQFYVANGELSCQ
Sbjct: 397  DYTGQGFDQLLDVIDKIKNNPDDRRIILSAWNPSDLKLMALPPCHMFAQFYVANGELSCQ 456

Query: 650  MYQRSADMGLGVPFNIASYALLTCMIAHVCGLVPGDLIHVIGDAHVYKTHISPLQEQLXX 471
            MYQRSAD+GLGVPFNIASYALLTCMIAHVCGLVPGD IH +GDAHVY+THI PL+EQL  
Sbjct: 457  MYQRSADIGLGVPFNIASYALLTCMIAHVCGLVPGDFIHALGDAHVYRTHIRPLKEQLEK 516

Query: 470  XXXXXXXXXXXPQTKDIDSFVAADFELINYEPHQKLEMKLAV 345
                       P+ K+IDSFVAADF+LI Y+PHQK+EMK+AV
Sbjct: 517  LPKPFPILKINPEKKNIDSFVAADFKLIGYDPHQKIEMKMAV 558


>ref|XP_008236926.1| PREDICTED: bifunctional dihydrofolate reductase-thymidylate
            synthase-like [Prunus mume]
          Length = 530

 Score =  822 bits (2122), Expect = 0.0
 Identities = 395/519 (76%), Positives = 454/519 (87%)
 Frame = -1

Query: 1901 SNGNADTQPPLHRTYQVVVAATRDMGIGKDGKFPWKLPSDLKFFKEITMTTSDPEKKNAV 1722
            +NGN +TQP   RTYQVVVAATR+MGIGKDGK PW+LPSDLKFFKE+T+TTSDP KKNAV
Sbjct: 13   ANGNGNTQPNPQRTYQVVVAATREMGIGKDGKLPWRLPSDLKFFKEVTVTTSDPGKKNAV 72

Query: 1721 IMGRKTWESIPPQFQPLPGRLNVILTRSGSFDMATAENVITCGSIPSALKLLAEPPYNIL 1542
            +MGRKTWESIPP+ +PLPGRLNV+LTRSGSFD+ATAENV+ CGS+ SAL+LLA  PY + 
Sbjct: 73   VMGRKTWESIPPEHRPLPGRLNVVLTRSGSFDIATAENVVICGSVASALELLAASPYCLS 132

Query: 1541 IEKVFMIGGGQILGEALNAPECDAIHMTEIESHMECDTFIPPVDLSVYQPWYSSTPEVEN 1362
            I+KVF+IGGGQIL EALNAP CDAIH+TEIE+++ECDTFIP +D SV+QPWYSS P+VEN
Sbjct: 133  IDKVFIIGGGQILREALNAPGCDAIHITEIETNIECDTFIPAIDSSVFQPWYSSFPKVEN 192

Query: 1361 NIRYCFVTFVRLKTSIGGPTNSSPEVRCNGSILDFKKFKVLNFTFLPRMIFEKHEEFLYL 1182
            +IR+ F T+VR+++S       + ++  + S  D  K +V NF+FLP+MIFEKHEE +YL
Sbjct: 193  SIRHSFTTYVRVRSSAVESLCQNNDL-ISSSKSDSVKCEVKNFSFLPKMIFEKHEEHIYL 251

Query: 1181 KLVQDIISNGNDKGDRTGTGTLSKFGCQMRFNLRKSFPLLTTKRVFWRGVVEELLWFISG 1002
             LV++I+S+G  K DRTGTGTLSKFGCQMRFNLRK+FPLLTTK+VFWRGVVEELLWFISG
Sbjct: 252  SLVREILSDGTSKDDRTGTGTLSKFGCQMRFNLRKTFPLLTTKKVFWRGVVEELLWFISG 311

Query: 1001 SPNAKVLQEKGIHIWDGNASREYLDSIGLADREEGDLGPVYGFQWRHFGARYTNMHADYT 822
            S NAKVLQEKGIHIWDGNASR+YLDS+GL D+EEGDLGPVYGFQWRHFGARYT+M+ADYT
Sbjct: 312  STNAKVLQEKGIHIWDGNASRDYLDSVGLTDKEEGDLGPVYGFQWRHFGARYTDMNADYT 371

Query: 821  GQGFDQLLDAIDKIKNKPDDRRIILSAWNPSDLKLMALPPCHMFAQFYVANGELSCQMYQ 642
            GQGFDQLLD IDKIK  PDDRRIILSAWNPSDLKLMALPPCHMFAQFYVANGELSCQMYQ
Sbjct: 372  GQGFDQLLDVIDKIKINPDDRRIILSAWNPSDLKLMALPPCHMFAQFYVANGELSCQMYQ 431

Query: 641  RSADMGLGVPFNIASYALLTCMIAHVCGLVPGDLIHVIGDAHVYKTHISPLQEQLXXXXX 462
            RSAD+GLGVPFNIASYALLTCMIAHVC LVPGD IH++GDAHVY+THI PLQEQL     
Sbjct: 432  RSADIGLGVPFNIASYALLTCMIAHVCDLVPGDFIHILGDAHVYRTHIRPLQEQLEKLPK 491

Query: 461  XXXXXXXXPQTKDIDSFVAADFELINYEPHQKLEMKLAV 345
                    P+ K+IDSFVAADF+LI Y+PHQK+EMK+AV
Sbjct: 492  PFPILKINPEKKNIDSFVAADFKLIGYDPHQKIEMKMAV 530


>ref|XP_010664720.1| PREDICTED: putative bifunctional dihydrofolate reductase-thymidylate
            synthase isoform X3 [Vitis vinifera]
          Length = 549

 Score =  821 bits (2120), Expect = 0.0
 Identities = 399/536 (74%), Positives = 450/536 (83%)
 Frame = -1

Query: 1952 RSYCEYSVMSENSIACHSNGNADTQPPLHRTYQVVVAATRDMGIGKDGKFPWKLPSDLKF 1773
            R    YSV+S +S   + NG+A   P   RTYQVVVAAT  MGIGKDGK PW LPSDLKF
Sbjct: 15   RVQTSYSVLSGDSAMSYPNGDARVHPVPQRTYQVVVAATHKMGIGKDGKLPWNLPSDLKF 74

Query: 1772 FKEITMTTSDPEKKNAVIMGRKTWESIPPQFQPLPGRLNVILTRSGSFDMATAENVITCG 1593
            FKE+TMTTSDP KKNAV+MGRKTWESIP  ++PLPGRLNV+LTRSGSFD AT ENV+ CG
Sbjct: 75   FKELTMTTSDPGKKNAVVMGRKTWESIPLNYRPLPGRLNVVLTRSGSFDNATVENVVICG 134

Query: 1592 SIPSALKLLAEPPYNILIEKVFMIGGGQILGEALNAPECDAIHMTEIESHMECDTFIPPV 1413
            S+PSALKLLAE PY + I+KVF+IGGGQIL EALNAP CDAIH+T+IE+ +ECDTFIP +
Sbjct: 135  SMPSALKLLAESPYCLSIDKVFVIGGGQILREALNAPGCDAIHITKIETSIECDTFIPTI 194

Query: 1412 DLSVYQPWYSSTPEVENNIRYCFVTFVRLKTSIGGPTNSSPEVRCNGSILDFKKFKVLNF 1233
            D SV+ PWYSS P +ENNI Y FVT+VR+++S       S  V  NG  +   K K+  F
Sbjct: 195  DTSVFHPWYSSVPLLENNILYSFVTYVRVRSSALESFALSSGVNFNGGSVP-NKLKIQGF 253

Query: 1232 TFLPRMIFEKHEEFLYLKLVQDIISNGNDKGDRTGTGTLSKFGCQMRFNLRKSFPLLTTK 1053
            TFLP+MIFE+H+EF+YL+ +++IIS+G  K D+TGTGT+SKFGCQMRFNLR SFPLLTTK
Sbjct: 254  TFLPKMIFERHDEFMYLRQLKEIISSGAHKADKTGTGTVSKFGCQMRFNLRLSFPLLTTK 313

Query: 1052 RVFWRGVVEELLWFISGSPNAKVLQEKGIHIWDGNASREYLDSIGLADREEGDLGPVYGF 873
            RVFWRGVVEELLWFISGS NAKVLQ+K IHIWDGNASREYLDSIGL DREEGDLGP+YGF
Sbjct: 314  RVFWRGVVEELLWFISGSTNAKVLQKKDIHIWDGNASREYLDSIGLTDREEGDLGPIYGF 373

Query: 872  QWRHFGARYTNMHADYTGQGFDQLLDAIDKIKNKPDDRRIILSAWNPSDLKLMALPPCHM 693
            QWRHFGARYTNMHADY G+GFDQLLD IDKIKNKPDDRRIILS+WNPSDLKLMALPPCHM
Sbjct: 374  QWRHFGARYTNMHADYMGKGFDQLLDVIDKIKNKPDDRRIILSSWNPSDLKLMALPPCHM 433

Query: 692  FAQFYVANGELSCQMYQRSADMGLGVPFNIASYALLTCMIAHVCGLVPGDLIHVIGDAHV 513
            FAQFYVANGELSCQMYQRSADMGLGVPFNIASYALLTCMIAHVCG++PGD I +IGDAH+
Sbjct: 434  FAQFYVANGELSCQMYQRSADMGLGVPFNIASYALLTCMIAHVCGILPGDFILIIGDAHI 493

Query: 512  YKTHISPLQEQLXXXXXXXXXXXXXPQTKDIDSFVAADFELINYEPHQKLEMKLAV 345
            YKTHI PL+EQL             PQ KDI+SFVAADFELI Y PHQK+EMK++V
Sbjct: 494  YKTHIRPLEEQLQKLPKPFPILKINPQKKDIESFVAADFELIGYNPHQKIEMKMSV 549